LOCUS       DARYSY010000001        75700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYSY010000001 DARYSY010000000
VERSION     DARYSY010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75700
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(318..611)
                     /locus_tag="TVR04_000001"
     CDS             complement(318..611)
                     /locus_tag="TVR04_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1268731.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASAPAKHRGLISIPFWLSNIFR"
     gene            1077..1548
                     /locus_tag="TVR04_000002"
                     /pseudo
     CDS             1077..1548
                     /locus_tag="TVR04_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1559..2917
                     /locus_tag="TVR04_000003"
                     /pseudo
     CDS             1559..2917
                     /locus_tag="TVR04_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            3011..3166
                     /locus_tag="TVR04_000004"
     CDS             3011..3166
                     /locus_tag="TVR04_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1268732.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(3348..3813)
                     /gene="tnpA"
                     /locus_tag="TVR04_000005"
                     /pseudo
     CDS             complement(3348..3813)
                     /gene="tnpA"
                     /locus_tag="TVR04_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(4100..4573)
                     /gene="tnpA"
                     /locus_tag="TVR04_000006"
     CDS             complement(4100..4573)
                     /gene="tnpA"
                     /locus_tag="TVR04_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1268733.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNEKTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            4628..4807
                     /locus_tag="TVR04_000007"
     CDS             4628..4807
                     /locus_tag="TVR04_000007"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268734.1"
                     /translation="MEAQSLVSHQLCWWFSCFSLREKLARSHNKNKNPAKKSLVGFLA
                     GNQINLSVSSNRSSL"
     gene            complement(4851..5216)
                     /gene="rplL"
                     /locus_tag="TVR04_000008"
     CDS             complement(4851..5216)
                     /gene="rplL"
                     /locus_tag="TVR04_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1268735.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(5281..5781)
                     /locus_tag="TVR04_000009"
     CDS             complement(5281..5781)
                     /locus_tag="TVR04_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1268736.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(5810..5945)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(6077..6718)
                     /locus_tag="TVR04_000010"
     CDS             complement(6077..6718)
                     /locus_tag="TVR04_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1268737.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MSKKSILHNYNILLTYLTNPFVSELKLASFSASGAGLKHFADVKMLFHMTQLIFGLLM
                     LPAIIYFYHRIKAHRLLLIRKELIAAALLPIVIACFALMIGFERFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQAAYH"
     gene            complement(6715..7482)
                     /locus_tag="TVR04_000011"
     CDS             complement(6715..7482)
                     /locus_tag="TVR04_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1268738.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(7482..8234)
                     /locus_tag="TVR04_000012"
     CDS             complement(7482..8234)
                     /locus_tag="TVR04_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1268739.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLTVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPKTRKVAMIPDDLVAPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGHEFLLHHRPCHLTLTYIKEVKPSTQITSGYHLEQ
                     LTSYHEIRSLGQLNAQAVIKWQPITTKESETN"
     gene            complement(8245..9375)
                     /locus_tag="TVR04_000013"
     CDS             complement(8245..9375)
                     /locus_tag="TVR04_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1268740.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQINSLKTLYIGGGTPTAITAKQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTIQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLQLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQAQGLLVKDKDFVRMTKKGLFLGDSVAEKFILD"
     gene            complement(9442..10095)
                     /locus_tag="TVR04_000014"
     CDS             complement(9442..10095)
                     /locus_tag="TVR04_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1268741.1"
                     /translation="MIKHRVDRIASQLDELTQKLYLTMIPEYQEGYANYIYQTDQPDV
                     QRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECYSMTADPEDYQS
                     ILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQEDGVSFLGSIEA
                     FASTTYPQKIYVLNIASFNKGAQSLCQKMGYQPISTFEQYTNGSNHAFVRMVKKKQS"
     gene            complement(10162..11514)
                     /locus_tag="TVR04_000015"
     CDS             complement(10162..11514)
                     /locus_tag="TVR04_000015"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1268742.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQELVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(11566..12522)
                     /locus_tag="TVR04_000016"
     CDS             complement(11566..12522)
                     /locus_tag="TVR04_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1268743.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTTKK"
     gene            complement(12519..13370)
                     /locus_tag="TVR04_000017"
     CDS             complement(12519..13370)
                     /locus_tag="TVR04_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1268744.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            13472..14815
                     /locus_tag="TVR04_000018"
     CDS             13472..14815
                     /locus_tag="TVR04_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1268745.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILATL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMITGITSTFLSAKKNKS
                     GKNIAVLEIDEASLSRVTAYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKKLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLSCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            14815..15603
                     /locus_tag="TVR04_000019"
     CDS             14815..15603
                     /locus_tag="TVR04_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1268746.1"
                     /translation="MTYTSLQSPENRDYQYDLRIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGDIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSIVSLAAYDDILQHETSEEYADIKSKANFDS"
     gene            complement(16061..17050)
                     /locus_tag="TVR04_000020"
     CDS             complement(16061..17050)
                     /locus_tag="TVR04_000020"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1268747.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDADMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILAKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(17285..19054)
                     /gene="lpdA"
                     /locus_tag="TVR04_000021"
     CDS             complement(17285..19054)
                     /gene="lpdA"
                     /locus_tag="TVR04_000021"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1268748.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDPVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQVGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPTQGAAPSAPKAALAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGAQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILTKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLEKLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     IHGSKTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(19263..20672)
                     /locus_tag="TVR04_000022"
     CDS             complement(19263..20672)
                     /locus_tag="TVR04_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1268749.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVSVTEVIGYIGAAGESVDNSTASSEKTTEILVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMGLSEFVLASKDVIKKAQGGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(20796..21794)
                     /locus_tag="TVR04_000023"
     CDS             complement(20796..21794)
                     /locus_tag="TVR04_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1268750.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(21874..22842)
                     /locus_tag="TVR04_000024"
     CDS             complement(21874..22842)
                     /locus_tag="TVR04_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1268751.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVIEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(23344..25254)
                     /locus_tag="TVR04_000025"
     CDS             complement(23344..25254)
                     /locus_tag="TVR04_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1268752.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVNRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRADEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLANYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIGLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLAKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEQEELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(25664..26449)
                     /locus_tag="TVR04_000026"
     CDS             complement(25664..26449)
                     /locus_tag="TVR04_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1268753.1"
                     /translation="MASISIEYHSEVLAMERHVKVIYPDQSELSPEEQGDQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     ISELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(26555..28216)
                     /locus_tag="TVR04_000027"
     CDS             complement(26555..28216)
                     /locus_tag="TVR04_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1268754.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGMLPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(28426..29184)
                     /locus_tag="TVR04_000028"
     CDS             complement(28426..29184)
                     /locus_tag="TVR04_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1268755.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLFLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRAGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(29181..30050)
                     /locus_tag="TVR04_000029"
     CDS             complement(29181..30050)
                     /locus_tag="TVR04_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268756.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGLATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDLKRIQDYLPFAADTNVLVAGLIVVVLVISLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRLELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISAVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(30064..31059)
                     /locus_tag="TVR04_000030"
     CDS             complement(30064..31059)
                     /locus_tag="TVR04_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1268757.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVVAASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVKVVDNGKPFLNVKVARDLGLVLSKDLLKRSDLTGKQ"
     gene            31410..33080
                     /locus_tag="TVR04_000031"
     CDS             31410..33080
                     /locus_tag="TVR04_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1268758.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTISDIALFEILQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEIKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(33169..34407)
                     /locus_tag="TVR04_000032"
     CDS             complement(33169..34407)
                     /locus_tag="TVR04_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1268759.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNAMEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALVIEYDDETVFELAAILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDAQLLLLASQ
                     LAFELHDSAGSEQYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(34397..35578)
                     /locus_tag="TVR04_000033"
     CDS             complement(34397..35578)
                     /locus_tag="TVR04_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1268760.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSDHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(35641..36117)
                     /locus_tag="TVR04_000034"
     CDS             complement(35641..36117)
                     /locus_tag="TVR04_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1268761.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(36295..37341)
                     /gene="rfbB"
                     /locus_tag="TVR04_000035"
     CDS             complement(36295..37341)
                     /gene="rfbB"
                     /locus_tag="TVR04_000035"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1268762.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHITVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(37531..38127)
                     /locus_tag="TVR04_000036"
     CDS             complement(37531..38127)
                     /locus_tag="TVR04_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1268763.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKPKYAFVNYA
                     DPSLGIAWESLEKAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(38127..38996)
                     /gene="rfbA"
                     /locus_tag="TVR04_000037"
     CDS             complement(38127..38996)
                     /gene="rfbA"
                     /locus_tag="TVR04_000037"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1268764.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPKDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(39053..40162)
                     /locus_tag="TVR04_000038"
     CDS             complement(39053..40162)
                     /locus_tag="TVR04_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1268765.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNENKLE
                     ELYQLANKRKQESPLIGDLAIRCRSDIRADFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVSISIEKQGYLVDGIVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLMDYHIANVATDNYAVVMPEGELDIIPFEHGRISVGASHENDKGYDLEPDLAVLEAL
                     EQEALTYYPKLSAASDISYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTVGP
                     LIAQQLVALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(40217..41005)
                     /locus_tag="TVR04_000039"
     CDS             complement(40217..41005)
                     /locus_tag="TVR04_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1268766.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLNLVKHDISVYVSHTNID
                     IVPDGLNDWFCELLGIDQTDVLVETQDGYGIGRVGNVAEQSLEELGLTVKKAFGLDAV
                     RLVRYAGQDPLISRVAICGGSGDEFYQAALAKGAQVYITGDIYYHVAQEMITEGLLAI
                     DPGHHIESLFIDQLVAKMQTWKKEEGWQVTIMASKVSTNPFSHL"
     gene            complement(40995..41681)
                     /locus_tag="TVR04_000040"
     CDS             complement(40995..41681)
                     /locus_tag="TVR04_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1268767.1"
                     /translation="MESHLSKRLRHVAAYVPDGARLLDVGSDHAYLPIFLVEAGQIQK
                     AIAGEVVKGPFASALKNVSQYGLTEHIEVRLADGLAAFEVRDAVDCITICGMGGRLIA
                     DILAAGKEKLQGVGRLILQPNNREDELRAWLSANAFRIIAETIMTENGKYYEIIVAEP
                     GQQSLTDHEQRFGPFLSQERSSVFVAKWQRELDKLVYALSCVPEARAAERASISQKIK
                     AIEEVISHES"
     gene            complement(41755..42417)
                     /gene="nth"
                     /locus_tag="TVR04_000041"
     CDS             complement(41755..42417)
                     /gene="nth"
                     /locus_tag="TVR04_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1268768.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLIAVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLI
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDSCPVQGYCSYYKTTYGKK
                     KV"
     gene            complement(42417..43094)
                     /locus_tag="TVR04_000042"
     CDS             complement(42417..43094)
                     /locus_tag="TVR04_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1268769.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELVPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKSELEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTVHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(43161..43679)
                     /locus_tag="TVR04_000043"
     CDS             complement(43161..43679)
                     /locus_tag="TVR04_000043"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1268770.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIAQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(43759..44127)
                     /locus_tag="TVR04_000044"
     CDS             complement(43759..44127)
                     /locus_tag="TVR04_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268771.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSPYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(44136..46346)
                     /gene="recJ"
                     /locus_tag="TVR04_000045"
     CDS             complement(44136..46346)
                     /gene="recJ"
                     /locus_tag="TVR04_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1268772.1"
                     /translation="MITSKYQWTIADKEPNAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMQKAVHRIRQAIEGFERILIYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAIAFAQ
                     AQGVDVIVTDHHSLPAELPKAFAIIHPEHPTAAYPFQKLAGCGVAFKLASALLETVPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     IGFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISGKNEERKALVQEIFAQA
                     MAMVDLEKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLSSDRLEELSELLCQYVTDRGHDGQKKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAAEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKAVVIDEVPDDIEALKALFRHREFEAIYFKNHIKHPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(46343..47107)
                     /locus_tag="TVR04_000046"
     CDS             complement(46343..47107)
                     /locus_tag="TVR04_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1268773.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLERLYQ
                     AISSKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAI
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERRVYVTTVNPGPIATAFFEQADPSGQYLASVASFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(47107..48036)
                     /locus_tag="TVR04_000047"
     CDS             complement(47107..48036)
                     /locus_tag="TVR04_000047"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1268774.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAAGVPFGPLFGKVKNGQDIELEDGTRIFAKDFISEPKKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(48051..48689)
                     /locus_tag="TVR04_000048"
     CDS             complement(48051..48689)
                     /locus_tag="TVR04_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1268775.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEIYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGELEDITP
                     EHALLTTIYRLPNEVTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(48682..49920)
                     /gene="hflX"
                     /locus_tag="TVR04_000049"
     CDS             complement(48682..49920)
                     /gene="hflX"
                     /locus_tag="TVR04_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1268776.1"
                     /translation="MIETKARQERVILLGVVLEAADHAELSMTELASLAKTAGAEVVD
                     CYMQRRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEAALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(50003..50893)
                     /gene="miaA"
                     /locus_tag="TVR04_000050"
     CDS             complement(50003..50893)
                     /gene="miaA"
                     /locus_tag="TVR04_000050"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1268777.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLKNQEAPYNPLMIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            51026..51202
                     /locus_tag="TVR04_000051"
     CDS             51026..51202
                     /locus_tag="TVR04_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1268778.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(51358..52005)
                     /locus_tag="TVR04_000052"
     CDS             complement(51358..52005)
                     /locus_tag="TVR04_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEL1268779.1"
                     /translation="MEKLLQAIVTAAANREKMLIRISGHGASGKSTFAKRLQQLLPDG
                     QSQLLETDAYIIANDFSQAVLISYPYQGKEVLHSITACHPARHELASLRRDIMMFKQG
                     LDFLSIDTPWAPSRLVKGDVPILIVEGMSTTFLEPELFDLSLYFYTDDDTELQRRLDR
                     DTRSRGRNPEFIQQSHAHRRTQYVRYLEPYQKQFDIVVNQSQNRFTVETCHISEN"
     gene            complement(52173..54437)
                     /gene="glgP"
                     /locus_tag="TVR04_000053"
     CDS             complement(52173..54437)
                     /gene="glgP"
                     /locus_tag="TVR04_000053"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1268780.1"
                     /translation="MKRFTDYTEMTLGKSLAGASNEEIYLSLLSYVKEEASKKTKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEIEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPH
                     LVTIIEQLDALVRARVSDLAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(54463..55965)
                     /gene="malQ"
                     /locus_tag="TVR04_000054"
     CDS             complement(54463..55965)
                     /gene="malQ"
                     /locus_tag="TVR04_000054"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1268781.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKIYANQNGIAIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFTAVREAL
                     GDLPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHHYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAADESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLKDDLKEKHKTYLIHLTELYGRANNHH"
     gene            complement(56170..57192)
                     /locus_tag="TVR04_000055"
     CDS             complement(56170..57192)
                     /locus_tag="TVR04_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1268782.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDLEAEVASERYMGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            57441..58694
                     /locus_tag="TVR04_000056"
     CDS             57441..58694
                     /locus_tag="TVR04_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1268783.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDAKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            58994..60355
                     /locus_tag="TVR04_000057"
     CDS             58994..60355
                     /locus_tag="TVR04_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1268784.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIRHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            60355..61191
                     /locus_tag="TVR04_000058"
     CDS             60355..61191
                     /locus_tag="TVR04_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1268785.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
     gene            complement(61277..62095)
                     /locus_tag="TVR04_000059"
     CDS             complement(61277..62095)
                     /locus_tag="TVR04_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1268786.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFAHRSAFLWWQNVILVLFLNALVL
                     MPITLHYASLKSYPLEQIVRNGLGSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEE"
     gene            complement(62120..62980)
                     /locus_tag="TVR04_000060"
     CDS             complement(62120..62980)
                     /locus_tag="TVR04_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1268787.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQERYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            complement(62981..64285)
                     /locus_tag="TVR04_000061"
     CDS             complement(62981..64285)
                     /locus_tag="TVR04_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1268788.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQFYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFLERFVPFAE
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            complement(64361..66493)
                     /locus_tag="TVR04_000062"
     CDS             complement(64361..66493)
                     /locus_tag="TVR04_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1268789.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHSKNIKVVI
                     DFAPNHTSTAEYKGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGKNETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGYHDIKVTTSTGQESNVYKAFEVLTDKQIPVRLVVNDFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAKYPNWFYDVNLPINKTINCHLVKKD
                     SSGNVLWTSPETYTIKTDSKAQTISLKK"
     gene            complement(66522..68222)
                     /locus_tag="TVR04_000063"
     CDS             complement(66522..68222)
                     /locus_tag="TVR04_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1268790.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHDAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHRAVQDYLIAIGLYWITEYDIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQSGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            complement(68395..69654)
                     /locus_tag="TVR04_000064"
     CDS             complement(68395..69654)
                     /locus_tag="TVR04_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1268791.1"
                     /translation="MAWDWKKAGVVGVVSLASTMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPNVIETLVMYYNKDLVSEAPK
                     TFADIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGTIEGLEYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            complement(70196..71170)
                     /locus_tag="TVR04_000065"
     CDS             complement(70196..71170)
                     /locus_tag="TVR04_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1268792.1"
                     /translation="MLMSIIVILLILAIAVLVIEHGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIRLTNAKLVFPNFEKAPYATYKEVYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLTEQGHFNQLIIAEQMIHAYAIFPIREARQARKQIAELVLKKE"
     gene            complement(71204..72457)
                     /gene="dltD"
                     /locus_tag="TVR04_000066"
     CDS             complement(71204..72457)
                     /gene="dltD"
                     /locus_tag="TVR04_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1268793.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            complement(72450..72689)
                     /gene="dltC"
                     /locus_tag="TVR04_000067"
     CDS             complement(72450..72689)
                     /gene="dltC"
                     /locus_tag="TVR04_000067"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1268794.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            complement(72707..73966)
                     /gene="dltB"
                     /locus_tag="TVR04_000068"
     CDS             complement(72707..73966)
                     /gene="dltB"
                     /locus_tag="TVR04_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1268795.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSPFIAVSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMI
                     FFPTFSSGPIDRFRRFQEDYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLL
                     LPLAENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNK
                     PFLSPNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVM
                     GLWHGLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKAFHALSIV
                     VTFHVVLFSLLLFSGFLNELWFNRPLR"
     gene            complement(73963..75501)
                     /gene="dltA"
                     /locus_tag="TVR04_000069"
     CDS             complement(73963..75501)
                     /gene="dltA"
                     /locus_tag="TVR04_000069"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1268796.1"
                     /translation="MVNDMIETIEYFAQVQPDFPVYDCLGERRSYGQLKEDSDSIAGF
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLVLGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLSDDFCQEKMPKLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            complement(75513..75656)
                     /locus_tag="TVR04_000070"
     CDS             complement(75513..75656)
                     /locus_tag="TVR04_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1268797.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT        22465 a        17640 c        13985 g        21610 t
ORIGIN      
        1 taacctaacg ataaaatcat tccaatagcg tagcacatga caacaacatt aaggtaaaaa
       61 taaatcattg tttctaatgt acttgacaaa atctccttta caagaatgat tgtaactaaa
      121 attggaatca aaattgtact tttaaaatat agccaaaatt gttttgcaat ttgagagatt
      181 gaaagaactt cctttgactg tttatagact aatgtaaaag ttaggagttc aagcaaaaaa
      241 ctccaaaaaa tgtgtcttat tttatgagtg cattgccaat ctacaactcc ttctaaatcc
      301 tgatctgaaa atatttttta acgaaatata ttacttaacc agaatggtat agaaattaaa
      361 cctctatgtt tagctggggc tgatgcgata gattgagcaa gaactataat cgcttttggt
      421 gcctcataat gatttgtcat tagataggtt gaaatatgtc ctgctaacct ggtactaact
      481 aaatacacag gctttttgag tgataattgc tggagacttt cttccaaaag attcctataa
      541 gtgacattat tttgcacctc ttcatctttt agagtctgtt ctatcagctg tactaaatct
      601 ctttcattca tgatttcaca cctctctata taaattaaaa ttatggacga cttgcccaag
      661 gtccatggtt aacccaacca ttgacaatta tcttaccaac atatggtcct gccacactcc
      721 agtccatacc acattttgca ctattttttc ctgtattcca acaatataca ccggtccctc
      781 caggtaattt tacaactcca ttttttccac cctcaactga tttcaattac tcttcagtca
      841 acgctataaa ttttgtatcc atgacgaata tctcctttat atgtgttttt attttgtccg
      901 gttgcaacct tgacagactt agtataacac tttctattaa aatttgttct ccatttccta
      961 aacagtcatc gaaacgtcct aaatgggaaa aatttaccgc ttaagactta aattcaaccg
     1021 tttgagataa tttgatagat ttgtcagatt accatttagg acgtttcgat aaccaatatc
     1081 tgcctcaaca agcttatatt tttagtggat caattttaga aaatcttact ctcggtgcaa
     1141 accaagcgat tactcaagag gatattatca atgcctgtga tatggcagaa attagagaag
     1201 atattgaaca aatgcccatg ggatatcaga cagagctatc tgatggggca ggattgtctg
     1261 gtggacaaaa acagagaatc tcattagcta gagcattatt aaccaagtct cctattctaa
     1321 ttctcgatga ggcgacaagc ggactagatg tcttaacgga gaaaaaagtg attgataacc
     1381 taatgtcaat gaccgagaaa acgattattt tcgttgccca tcgtcttagt actgctgaac
     1441 atactaacca aattgttgta cttgataaag gaaaaataat cgagataggt tcgcataacg
     1501 aattaatgac gcaccaaagg cttctatcat catttattta gtaagtaagg agatattcat
     1561 gaatccaaat ctgtttagaa gtgctgaatt ttatcagcga cgctatcata attttacgat
     1621 aattcttatt ataccactaa cattactcgt catattttta ctttcatttt cttttcttgg
     1681 tcaaaaagaa gtaacggtat cgtcacgagg tgaaattatg cctacaaaag tcattgcatc
     1741 aatacagtca actagcaaca atgctatcgt taaaaataat cttaaagaaa accaactcgt
     1801 taaaaaagga aaacgtttaa tcaaatataa agaaaccatt gagagttctc aaaagaattc
     1861 tctagaatca caattaaata cgttgaataa acaaaaagtt ggtttagaga cattgaaaga
     1921 aagtctcaaa caaggaacga acctcttacc acaaaatgat gaatttggtc ttgctgacac
     1981 cttcaacaac tttataaatc agtctcaaga gattaaactt ggtatcgcta aaataaatac
     2041 agaagtatcc aatcaatcca cacttgcaaa taacaccctt gctgcaattg atactcaaat
     2101 caatactata aaccagcaga tttcagaata tgaagatctt cgtcaagcta tctcaaatca
     2161 taacacaatc ttaccaactg gtaatcctca tcaagatatt ctcaataatt atctgtctca
     2221 atcacaagaa gaacaaactt ccacgtctaa ccagtttatc tctcagatta accagactat
     2281 ttcaggttta gaatcatccc tctctgggct tagcattcaa agagcaggta ctggtagtag
     2341 tgcaacatac gataacagtt cagaaaccaa agttgaagtc ttgaggactc aatttctaca
     2401 gaatgcttca caacagctgt caaccatcga cagtcaaatc actgaactta aagctcagct
     2461 agaacaagca agtgtatagt tagacactaa tgttgtttta gcaccagaaa ccaggattat
     2521 tcatctaaat aatgaatacg aggggaaaag tcttatccca aatggtagtg atattgccaa
     2581 aatctatcct aatattactc aaactagaaa agctctgatt acatactttg taacttctga
     2641 ttatgtttct ctccttaaaa aaggtcaaac tgttcgtcta aatcttcaaa aagtgagaaa
     2701 acagtccatc actgttaatg gaaaaatttc tactattgat aaaacagcaa caaaaacaga
     2761 acaaggtaat cttttcaaga ttacaactct tgccaaactc ccttccaagg atagctactt
     2821 gataaaatat ggtgcacagg gtcgtgttac aagtgttatc gctaaaaaat cttacttcga
     2881 cttttataag aataaactgt tgtcaaatca tgattaaacc attccggacg tttcgatgac
     2941 catttaggat ttagagaaat aatatattga tcttaaatta taatattaga aaaaagaagg
     3001 aggtccacaa atggaaaaac aaaattcact cactcaattt caagaactaa attcatccga
     3061 actcaatcaa ataacaggtg gagattggtg gtcagagata ttaaatttta atcgctctca
     3121 aaaatataaa catacctccg tgggttctaa taatattatt gtctaacata tacttagtat
     3181 tgtaataata gtttttttag tagaaatcat aaccacccgt ccaacaggtg gtttgaatag
     3241 ggactataaa cccatataac tagccagcgc ctaaagacgc tggctttcac tttgttcaaa
     3301 ccacattgct attgactcgt cacttgcctc tcaaagaagt atttgtatca cttaccctta
     3361 tctctaaagg gatcctcata ttcttttaca ctcagtttat ctagtgctat gtcatgtttt
     3421 tcttgttctt gaatatattt ttttattgta gcttcattta atccaaccgt actaatataa
     3481 tagccttctg cccaaaagtg tcgattacca aatttgtatt tcagattggc gtgcttgtcg
     3541 aacatcataa gcgtactctt accttttaaa tatcctataa aacttgaaac acttattctg
     3601 ggtggaatgc ttactaacac gtgtacgtga tctggcatca gatgtccttc tatatatttc
     3661 tacaccttta tagctacata atctttgaaa aatttctccc aaactgcctc gatattgatt
     3721 atagattact tttcgtctat acttaggggt gaacacaatg tgatatttac aatgctactt
     3781 tgtgtgcgat aaactgtggg gcttttgtgc catattttta ctcctttcgc tttacaattg
     3841 gcttgaacac ctatattgta gcgcgtttgg agtttttttg tagtataacg ttcgatgcgc
     3901 acccgcatag cgggggattt ttgtttcaca cctacggagc gaaacggact aaagtcacta
     3961 agtcataacc acgcgtaaaa acgggtggct tgtacaccgg ctataagccg tttctctcca
     4021 gcgacgtcta aagacgttcg ctgaacttcg ttcaggttag tgctatgatt acttgactaa
     4081 tgcccgtaaa aacgggcttt tatcttgttt taaaactgcc atctgaaaat ggatcttcat
     4141 attctttaac actcaactta tcaagtgcaa tgtcattttt ctcctgctcg cgaatatatt
     4201 tcgctaccgt cttttcgttc agtccaacgg tactaacata gtagcctcta gcccaaaact
     4261 ttcgatttcc atacttatat tttaaattag cgtgtttatc aaatatcatg agagcacttt
     4321 tacttttcaa ataccccatg aaatcggaaa tcgaaagttt tggaggtagc aagacgagca
     4381 tatgaacatg atctggcatc atatgtccct caatgatttc cacgcccttg tattgacata
     4441 ggtgacggaa aatatcaatt aagtcctgtc taattttgta gtaaatggat tttctgcggt
     4501 actttggtgt gaaaactatg tgatatttgc acatccattt ggtatgtgat aaactgtaac
     4561 tggttttagc catctctttt tcctccttga tctaacctga acaattagat tataacagga
     4621 aaaagaaatg gaagctcaaa gccttgtcag ccaccagcta tgctggtggt tttcttgttt
     4681 ttctctacga gaaaaactgg ctcgaagcca taataaaaat aaaaaccctg ccaaaaaatc
     4741 tttggtaggg tttttagcag gaaaccaaat caatttatca gtttcttcaa atcgctcttc
     4801 gctttaaaag gctagtaaat tgggcttccg caatctcttg cgatactcta ttatttaaga
     4861 gtgatagttg ctccagcttc ttcaagctta gctttgattt cttctgcttc tgctgctgca
     4921 acaccttctt tgatgttagc aggtgcgccg tcaacaagac ctttagcttc tttaagtcca
     4981 agacctgtga tttcacgaac tgccttgata acaccaactt ttttgtcacc agcagatgtc
     5041 aactcaacgt caaatgaatc cttagtagct tcttcagcac caccagcagc agctacagct
     5101 acaggagcag ctgcagtcac accgaattct tcttcgatag cttttacaag atcgttaagc
     5161 tcaaggattg aagcttcttt aatttcagca ataatgtttt caatgtttaa tgccattgtc
     5221 atttcctcca aatagttata ttaaataatg atttgtagct ctaggctacc tctaaaggcc
     5281 ttacgcagcg ccttctttgc tttctgcaac agccttgaca gcgtatgcaa cgttgcggac
     5341 tggggcttga agtacagaaa gaagcataga aagcattcct tcgcggtttg gcaatgctgc
     5401 aagtgcttga atttcctctt ttgaagaaac aacaccttcg atagcaccac ctttaatctc
     5461 aagtgcttca gcagttttag caaagtcgtt gatgacttta gctggtgcga taacatcttc
     5521 atttgaaaat gctactgcag atggtcctac gaatatgtcc tttaattcgt cgagacctgc
     5581 tttttcagct gcacgagtca agattgagtt tttgataacc ttgaactcaa cgccactttc
     5641 acgaagtgaa cgacgaagaa cagtatcttg atcaactgta agaccacgtg aatctacaac
     5701 aacgatactt acagctgctt tcattttctc agcgataagc tcaacttgtt cagctttttt
     5761 agcgataatt gcttcactca ttagttttac ctccgttttt atttttgggc taggcacaaa
     5821 aaaatcgcac ctaaacctag acacgaaagt acaaatacgt tatcttcaat aattacgctt
     5881 tgtgcctcgg caggaatatt acgagcacgc tcccctgctg tcttaggtca gttttattca
     5941 aaaccatagt tagtatagcc tttttaaatg actttgtcaa cctatttttt agaaaatctt
     6001 aaataaaaaa ggaaagctct tggctttccg ctaaatagat ctgattagtg gctcaaaagc
     6061 gcctcctaac ttaagcctaa tgataagcag cttgtgacga ttgattgcta tagcttagcc
     6121 cgatcaagct ccacaatatc atctcgtaaa tgaagaagaa taaggcaaag caatgaccaa
     6181 aaaaggcctc tggcaatatc caaattacag gatctgtcag cggatcaaac aaccagcttg
     6241 aatctcctac aaagagaatt tgatgaaaaa gggtaaaaaa acgctcaaag ccaatcatca
     6301 aggcaaagca ggcaatcact attggtaaca gggccgctgc tatcagttct tttctgatca
     6361 gcagcaatct atgagctttg atcctgtgat aaaaatagat aatagctggc aacataagca
     6421 ggccaaagat gagctgtgtc atatgaaaca gcattttcac atctgcaaaa tgctttaagc
     6481 cagcacctga tgctgaaaag ctagctagct ttagttcact aacaaaagga ttggttaagt
     6541 aagtcagcaa tatattatag ttgtggagaa tggacttttt actcatcaaa actgcctgct
     6601 ctagttgcaa ataatcaacc tcaatcggat aaagcagcca agataaatag atagttatca
     6661 aaactgccag tgctagtagc caaagccaac tggcaatgaa cttgcctttt tcaatcataa
     6721 tagctcccac tcatctaagc tggccaagac atgatcaggc ttaattggaa ggcttggaac
     6781 ctcttttgcc tttgtaaagc cggttgttac tagaatagtt gccatatcat tttgaattcc
     6841 tgccatgata tctgtcaggt aattgtctcc aaccatagcc acctcagaac gtggtacctt
     6901 taagatctct agggctttat tcatgataat cgcatttggc tttcctataa atactggctt
     6961 cactctagtt gctgcctcaa ggagcgcatt taaagcgcca gcacctggca ttagcccacg
     7021 ctctgttgga atatttaagt caggattggt cccaataaac aaggctcctt tttgaatggc
     7081 aagtgttgca attgataaca tttcataggt aacctcagta tctaagccaa caacaacata
     7141 ggctggattt tctgtatcct cggtatagcc tgcctctgca atggcagact ttaagccagt
     7201 ctcgccaatc acataggctg ttttgcctcg attcatatca ttcatgtaat caacggttgc
     7261 cattgtagcg gtgtaaatgg tttcaagacc tgtatgaacg ttaaattgat tggctagcat
     7321 ttcctgaacc atttcaggtg ttcttgtggt attgttggta actaagagat aaggaatacc
     7381 tttttcctgt aaacgcttga taaagcgctc accagctgga atacgatttt tcccttgata
     7441 gatggttcca tctaaatcaa ttaaataagc tttatagggc actaatttgt ctcactttct
     7501 ttagtcgtta taggctgcca tttgataaca gcctgcgcat taagctggcc taatgaccta
     7561 atctcatggt aggaggtcag ctgctctaga tgatagcctg aggttatttg agtgctgggc
     7621 ttcacctctt tgatataggt caaggtaagg tggcaaggcc tgtggtgtaa taaaaattca
     7681 tgtcccaaaa cgtcatacat ccaatccaaa tacttactat tattggcatg accattcata
     7741 tcaatgtcaa aataacgaac ctgataagct tgaaccatag gatcctgaag ctcatctatt
     7801 ttgataggac gcttgatttt cttaacaaag tcagcctgat aaggcgccac taaatcatct
     7861 ggtatcatag ctaccttacg tgttttagga tttagcaggg caaaatgaga taaaatggtc
     7921 atgatggcat gacctgcctg atcataaatg tgaaattgcc ggtaacaaaa taatttattg
     7981 taagaaatag cttgcgtttc aatggttact gtttccccaa accttggcat acgatcaatc
     8041 gttacatcat aatccgtaac aacccaaatc aagccatatt gctgaagtaa cacctcattg
     8101 cctcgtccaa tttcagctga ttgtcttgct gataccgtta agcaatgtgc taataaaagg
     8161 ggcagcttga catcagcctt aacatcacaa aaatcaaaag acagcttaag gctttcacta
     8221 taccttaatc ccataacaca cctcctaatc taagataaat ttttcagcga cagaatcacc
     8281 taaaaagagc ccttttttag tcattctgac aaagtcctta tcctttacca gaagcccctg
     8341 agcctgaagc tctctcacaa cagggccata gcgtgactca aatgataggc caaatttttc
     8401 ttgaaaccga ctgactgata ctcctgattt ttttcgcaga ccaagaaaaa gctcctcctc
     8461 catcatctcc tccttggtga gcacttcctc acttaaccta gcatttccat ctgctactgc
     8521 ctttaggtaa tgctgaatag gaacccggtt gcggtaacga atcccatcaa gatagccaga
     8581 agctcctgca ccacagccaa agtattcatc attattccaa tacatcagat tgtgtctgct
     8641 ttcaaagcca ggcttggtaa aattggagat ttcgtaatgc tcaaagccac tggcttccat
     8701 ctcagaaata atatactcaa acatctctgc ttccaaatcc tcagtcggca actggagctt
     8761 gccacgacgc attttgttca taaaaacagt gtgatgctct aggataaggc tatacaggct
     8821 aaggtgagga atatctaaag caagtgcctt agccacattt tccttgacct gctgtatggt
     8881 ctgtccaggc aaagcataaa tgagatcgat agacatattt tgaaagcctg cctccttaag
     8941 gctagcaatg gtcgtataaa tctgagcctc agtatgactg cgtccaatct gctttaattg
     9001 cttgtcatta aaggtctgaa cacctaggga aatccgattg acagccgatt gccttaatac
     9061 tgcaatctta tcctcagtca aatctcctgg attggcctcg atggtaaatt cttcaagctg
     9121 gtctagctgt aggtgctgct gcaaatggct cagcaaataa tcaagctgct tggctgttat
     9181 ggctgttggt gttccaccgc caatataaag tgtcttcaag gagttgatct gataggattc
     9241 aaattccttg atcaatgcct ctaggtaggc atcgacaggc tgatttttga taaatacctt
     9301 agaaaaatca caataatagc aaatttgtgt gcaaaaagga atatgcacgt aggctgaggt
     9361 tggttttttt gacatggtaa tattatatca ttttagctca gaaattcatg ccaagtgatt
     9421 agctttttga catgcgctag cctaggattg cttctttttc accattctca caaaggcgtg
     9481 attgctccca ttagtatact gctcaaaggt tgagattggc tgatagccca ttttttggca
     9541 gagactttgt gcgcctttat taaagctagc gatatttaga acatagattt tttgcggata
     9601 agtggtgcta gcaaaggctt caatgctgcc caaaaaagaa acaccatctt cctgaccagt
     9661 agtatcaggg gccataccaa gaccaatctc aagctctgat tcctgttcaa aaaagctggc
     9721 aaagccaaaa agaacaccat tgcgaagcac ttgaaagtaa tgctctccac gcgccttggg
     9781 tgacaatatt gactgatagt cctcaggatc agcagtcatg ctatagcact cataagctgg
     9841 gctatagatc cagtcatgcg caatgatttc agcactatgc tgtgtcatcg gcatcaggta
     9901 aaaagaagac tcagacaata agcgatgaaa ggtcttgttg atatgcttta tgcgacgccg
     9961 ctgcacatca ggctgatctg tttgataaat gtaattagca tagccctcct gatattctgg
    10021 aatcattgtc aaatacagct tttgggtcaa ctcatcaagc tgactagcaa tcctatccac
    10081 tctatgcttt atcatattac ctccaattct aatactgctt gatagcataa aaagtgccga
    10141 agcaacgaca ctttttctag attaatcaag gccaatttcc gcacgaacaa ccgctgcaat
    10201 ggtatcaaca taatagtcaa cctcttcatt gcttggtgcc tctgccatca cacgcaacaa
    10261 tggctctgtg ccgctaggtc ttaccaaaat gcgaccatta ccagccattt ctccttccat
    10321 ctgagcaatg acctcagcaa tggcaggcac ctccatagca cgctccttca tgctgttgtc
    10381 aacacgaata ttaacaagct tttgtgggta aatagtgacc tcactggcca attcggagag
    10441 agttttacct gtctccttca tgattttggt gagctgaaca gctgtcagtt gaccatcacc
    10501 agttgtattg taatccatga taatgacatg ccctgattgc tcaccgccaa gattgtagcc
    10561 gaactgacgc atctcctcaa caacgtagcg atcaccaaca gctgttacct tcttatgaat
    10621 gccacagcta tctaatgcct tgtgaaaacc aaggttagac atcactgttg tcacaatcgt
    10681 atttttagct agcaagccct tctcagaaag atacttgcct atgataaaca tgatcttgtc
    10741 gccatcaaca atagcaccat tttcatcaac agcaattaag cgatcactat cgccatcaaa
    10801 ggccagccca atatcagagg ccgtttctgt caccaattcc tgaagctttt cagggtgtgt
    10861 ggagccgata ccatcattaa tgtttagtcc atttggattc tcaccaataa ctgtaatgtc
    10921 tgcatttaaa tctaaaaaga cattacgagc tgaaacagaa gctgcaccgt tagcagtatc
    10981 aagagctatc tttaaaccgt ctaaatctgc tccagtagta accaagaatc tctcgtactt
    11041 gcgcaagcct tctggataat caaccaaggc tcctaagccc tccgcacttg gacgtggtag
    11101 gaggtcctct ttggcgtcta agagcgcttc gatttctagc tcttgctcat cagccaattt
    11161 aaagccatca ctcccaaaaa acttaatgcc attgtcaaga gcaggattgt gactagctga
    11221 aatcatgaca ccagcactag ccttttctgt acggaccaaa taggacacac caggagttgc
    11281 aagaacacca agcttataga cctctatccc aacagaaagc aagccagcaa tcagggctgc
    11341 ctctagcatt tcaccagaga tacgggtgtc acgagcgaca aaaactctag gcctttcagt
    11401 ctcgtgctga cttagcacat aaccaccgaa ccgaccaagc ttaaaagcaa gctctggggt
    11461 caactccaca ttagcctcgc ctcgaacacc atccgttcca aaatattttc ccataattat
    11521 atcagctaaa cgcttcctcc attccatttt cctagctatt atgctttatt ttttagttgt
    11581 tgtcaactga acggttacca ccgaaggctc tatagaaacc tgatttgaaa ccaagctgac
    11641 cgttttgctc gtgtttttgg tgacatcaga aatattgacc tctgccacca cctcatcaat
    11701 agtttcaagg acctcccgac taccagaaat aacagcggtc tgcttggaga gcttatactg
    11761 gatatctgac agactgtcat ccattagtcc aactgcctcg actcgaatag gaactgattt
    11821 ggtgattttt ttgacagaaa ctgacaaatt agccttggct ggatcgatcg cactagctaa
    11881 gatggtacca tcggcagcta ctgcctgcag ggttactcgg ctgctataat tagcatctag
    11941 cacctgatca tcaggtaatt tagcgacaac atgatctatc aaggcaatag tagactcatc
    12001 acttgtgacc tcaaccttgt caatacctgt ttcaattttg ctaatctcat agcccttagc
    12061 cagctgctta ctatcgacgc tgccacgcac cggaaaggtc tttgttttct tatttccaat
    12121 cgttaccgaa atcttatcag gagaaacagt tgctgtcaca ccagtaggta gattgataac
    12181 ctttagggtc accgttgcag tacctggctt actctttgtt agatcagcta cgatcttaaa
    12241 gcttctagtg tcactgttta cctctgaatc cagctttatg cggttggtag aggtcagata
    12301 aacctctgca ccgtaagaat agccgctgat gaagtactga tcactatcat acttgatatc
    12361 aataggaacg tcctttaagc tatgggtgta ggtttcaata gggctataaa tttgagaatt
    12421 agaatgatta tgactgctag aagcagcggt caaaaaaaga ataatcgcaa aaaagattga
    12481 cactaagccc agcccaagac gactatttaa aaacctcttc atttagcttt gcctcctaag
    12541 atttttttat accaaggtaa tgtcgcaccg ggctcattca tcaaatgagt cttgagaacc
    12601 gcctcaagct cttctgttga aaggtcgtgt aaaaattgac ccttacgagc gatagagaca
    12661 gctcctgtct cctcagagac aattatcgtt acagcatcag aattttctga aagtccaatt
    12721 gctgctctgt gacgtgttcc aaattctttg gaaatcgaca ttgattcaga caaggggaga
    12781 taagcacagg ctgcagcgat tttattgtta gccacaatga ccgcaccatc atgcagcggt
    12841 gtgtttggga taaagatatt gatcaatagc tgactagaaa tatcagcatt taggggaatt
    12901 cctgttgcga tatattcctg caaggtctgc gtttgctcaa tagcaatcag agcaccaatc
    12961 ttccgcggtc ccatataagc aactgatttt aagagcgcat caaccagcat ctcctcatca
    13021 ctcaagcttt gcttttgcaa aaatacctgt gttgatcggc caaatttttc aagccccgct
    13081 cgaatttccg gagcaaagat caccacacct gcaatcactc cataggtgat gacctgattc
    13141 atcagatagg ttatagtcgt aaaccctatc cactcggcaa tcacacgaat gatgataaaa
    13201 aatataaccc cttgtaccaa ggacatgatt ttagttcctg ccaaggattt aataaaacgg
    13261 taaatcaaat aggctactat taaaatatcc agcaaatgaa ccaccaacat caaggggtca
    13321 tcaatcaggc ttagtaaaaa ttttgtgtca atacttgata aattactcat acaattctca
    13381 tttctatgtc agatagatac ctctaacatt atatcacgtt tcaagatgtt ttccctatct
    13441 aaaatttaag aacttatgtt aaaatattaa catgaaacta aagacactac tcgctatagc
    13501 agccggaagg actgcgcagc tcattttaaa taaaatcgga agaggctcaa cctaccccgg
    13561 acgattggcc ttgatgtggg ataaggacat cttagccaca cttgccaagg actatgagat
    13621 tgttgttgtg acaggaacaa atgggaaaac cttaactaca gctctaactg ttggtatctt
    13681 aaaagaggct tttggtgagg ttttgaccaa tccaagcggt gccaatatga taacagggat
    13741 tacctctacc tttttgtctg cgaaaaagaa caaatcaggc aagaacattg ctgtcctaga
    13801 gattgatgag gcaagcctgt caagggtaac agcatacatt aagccaagtc tttttgttta
    13861 cactaatatc tttcgagacc agatggatcg ctatggtgag atttacacca cctatcagat
    13921 gattgttgat ggtgctagtc aagcgccgaa ggcaaccatt ctagctaacg gtgacagtcc
    13981 tatctttgcc tcaaaaaaat tggttaatcc tgttaaatat tatggctttg acacacctaa
    14041 gcatgagcca cgcctagctc actacaacac tgaaggcatt ttgtgcccaa aatgtgaaca
    14101 gattctccgt taccgtctca acacctatgc taacctagga gattacacct gcttaagctg
    14161 tgatttccaa aggcctaagt tggattacaa gctaacgcaa ttaaccagca ttacccatca
    14221 cagctcagcc tttgtgattg acgatcagac ttatcgcata aatgtcggag ggctctataa
    14281 catctataat gccctcgcag ctgttgctgt tgctgagttt tttggcattt ctgctgatca
    14341 gattaaggct ggcttcaata aaagcaaggc tgtttttggt cgtcaggaaa ccttctccat
    14401 caacggtaaa gcctgtacgc tggttctcat taaaaaccct gtgggtgcca gtcaggcact
    14461 agaaatgctg cgcctagccg attacccctt tagcctatct gtgcttttaa atgcagatta
    14521 tgctgacggt attgacacta gctggatttg ggatgctgat tttgaattga ttaaccaaat
    14581 ggacattacc gaaatcaacg ccggtggggt tcgacattct gaaattgcaa gacgcctacg
    14641 agtgacaggc tttgatgagg ctaaaatcac atcattcgat aagcttgaag gtatcatgca
    14701 agccattgaa aaccaagagg ctgagcatgc ctatatccta gcgacctata ctgctatgct
    14761 agcatttcgt gagctgcttg ccagccgcca cattgtcgaa aaggagatga tctaatgacc
    14821 tatacctcac tacaatctcc ggaaaatcgc gattatcaat acgaccttcg tattgctcac
    14881 ctttatggta atttgatgaa tacctatggc gataacggca atgtcttgat gttgaagtat
    14941 gtcgctgaaa agctaggcgc tagggttaga gttgatattg tatccattgg ggataccttt
    15001 gaccaagatg attatgacat tgttttcttt ggtggtggtc aagattatga gcaagccatt
    15061 gttgctagag atttgccatc aaaaaaagag gccttagcag cctatattca ccaaaataag
    15121 gtactccttg ccatttgcgg tggctttcag ctactgggac agtactatat tcaagccaat
    15181 ggccttaaaa tcaatggcat tggggttatg ggacattata ccttaaacca agataataac
    15241 cgctttatcg gagacattaa aattcacaat gatgactttg acgaaaccta ctatggcttt
    15301 gaaaatcatc aaggacggac ctttttatct gacgatgaaa agcctcttgg acgtgtcatt
    15361 tatggaaatg gtaataataa agaggaccaa actgagggtg ttcactataa aaacgtttac
    15421 ggcagctact ttcatggacc aatcctttcg cgtaatgtca gcctggccta tcgcctagtc
    15481 acaactgctc tcaaagaaaa atatggctcg attgtttcct tagcagccta tgatgacatc
    15541 ttacagcatg agacctcaga ggaatacgct gatattaaaa gcaaggctaa ctttgacagt
    15601 taagtccttc tcatagcctg atcaagcgaa acaaccctca aaaaagtatc aggacaacaa
    15661 taaaatggct atgcccatat accaatgtag ccctcctcct ctcactgcac agacaggcta
    15721 ggagaggctt ttacgctagg tttgagctca gcgatctaga acagaccttg cttgtttgca
    15781 gtaagcctga tatactttcg gcagcaaaga ttgaatcctg ctataaggca ctgccaaaaa
    15841 gactagccca aaaatccttg cagtatttga catttttggg gataagtgcc gaggtaccag
    15901 ctacagagca ggaagtctat gtgaccggca ccaaaggaca caaaaaacta aagtcacaca
    15961 ctaaaagcca catgactccc cctatcaaaa ggataggtgt catgtggctt ttttctatct
    16021 cactgttcgt catagaaagc cagatcagct tctttttgaa ttaggcgaca atggcctttg
    16081 ccacctcttc tactgtcata cgtgagaaat attgtgttgt gtcaatggtt tgaagacgct
    16141 caagcacatc agcatactcg tatttgcaac caatgagtag gctttcaata tcctgcacgt
    16201 ccttaatacc aaagaaatca ccgtagatct taagattctt aataacagaa ttttcaacat
    16261 tagcaaaggt tgagatttta ccggcagggt agcgaacatt acgttcaatc gtgtattcag
    16321 gtgcctttcc ataggtccaa tcccagctcc caaattgctc ctcagccgat tgttgaatct
    16381 tagccagctc gtcctctgac aagacgtatt ctgtcatgtc tggataggtc tccttcattt
    16441 tagccaaaat cttgtctgaa aatgcttcaa cactgatctt ttctggcagc tcatttaaaa
    16501 tattggtcac gcgggcccgt acagacttga ctcccttgga ctcaatcttg tccttactta
    16561 ccttgagagc atcacccagg acagtcatat ccgcatcaaa caagaggcag ccatgatgca
    16621 tcatacgtcc cttgtaatag gcttgggcat tcccacagat ttttttgcca tcaatttcga
    16681 tatcattacg acctgtaaaa ttggccttga cccccaagtc agccaaggtt tcaatcactg
    16741 gctgtgaaaa ggttttaaaa tcaaaggctc cttctgctgt tttattggaa ataatggtat
    16801 agttcaaatt atttaaatca tggtaaactg caccaccgcc ggacaaacga cgaaccacgt
    16861 gaataccatg ctgatcaatg tattccttat tgatttcctg aatggtattt tggtgcttac
    16921 caataataat agccggctca ttgatccaga ggataaacaa ttcatcctca tcaaccaatt
    16981 ctctaaaggc ataagcctct agagcgatgt taaaggcagg gttgtggctc ttattaacaa
    17041 tgtatttcat ttctatctcc tatagcgata atcgttatca tgtcctattc tttattctaa
    17101 tggaaactct tacaaaagac aagctaaatg aggctaacag ggcaaggaag ctaacaaatg
    17161 cttctttgat caaaaaccat cagcaatgct agcagcaaaa cttgttctaa cttaaagagc
    17221 cttccttgta ccaaggaaag agctgagaaa ttttcccagc ccttttttat cgtagctata
    17281 tagcttattt tttacgcttt ggtgggttat gaatggcttc gccaaggaca tctgcaaagg
    17341 cttcgtacat tacttctgag aaggttgggt gtccatgaat tgacaatagc aactcatcaa
    17401 ccgttaactc agcctccatg attgtggctg cttcattgat catttcagcg gctgctggac
    17461 caatgatgtg aacaccaagt atttcatgat atttagcatc tgcaataacc tttacaaagc
    17521 catgagcctc atttgacgca atagcacgac catttcctgt aaagctattt ttcccgataa
    17581 gaacatcgcc atattgctca cgagcctgct cttctgttaa gccaaccatt gccacctcag
    17641 ggtgagtata taccgctgct ggagtgtatt taaggtttgc cttacgtgtc ttgctaccat
    17701 gtatcgcatt ttcagcagcc acctcaccca tacgataagc agcatgggca agcattttag
    17761 tgccgttaac atcacctggt gcataaattc ctgggattga cgtttcttga tagtcgttaa
    17821 ccttgatacg gttgcgatcc atctcaaggt tcagcttttc aaggccattc atttgtggca
    17881 cacgtccgat agaaagcaag gctttttcag ccacaacctc ttcgccatta ttaagcttca
    17941 aggtcaactg gttgttggct tcaacaatct cagagacacc aactgaggtc tttattgtca
    18001 tgcctttctt agtaaggatt ttttgaagct caagtgaaac ctccttgtcc attgctggta
    18061 taatacggtc agccatttca ataactgtaa cctctacacc ataagaggcc caaacaagac
    18121 caagctcaat accaacaaca ccaccgccca tgacagctaa tgattttggc atttcacgca
    18181 aatcaagaat atcatcagat gtcaagacaa gcttagaatc aattcccgga atattgatgc
    18241 gtgagacctt agagcctgtc gcaagaataa tattgcgccc tttaatggtt tgcgcaccaa
    18301 tggtaaccgt tttatcagga tttacctgac caaggccatt aaagatggtt accttgttgg
    18361 ctttaagaag cccttgaacc ccacctgtta gcgtcttaac aaccgtattt ttaaagtcaa
    18421 ccgtcttatc catgtcaata gtatagttgg ttgaagcaag gttaataccg cgtcctgctg
    18481 caatcttgat gccatcaagg atttcagcat ttttaaggta ggtctttgtt gggatacagc
    18541 caacattcaa gcaggtaccg ccaaattcag atttttcaac gatagcaatc ttgccgccca
    18601 gctgagcacc acgaatagca gcgtagtaac ccgcaggacc gccaccgaca acaataatgt
    18661 catattcatc agcagcaagt gctgctttag gtgctgatgg cgctgctcct tgagtcggtg
    18721 cctttggcac ctcaagacca gccgcctgta aatcctcggt tgtacgcgca acattgacat
    18781 cagccgctgc tgggcttgat acatcgatag cttcacctgc agctccaatg tagccgataa
    18841 cttcggttac agggactgtc tcacctacct ggcgagtgat ttttagaagc acacctgagt
    18901 cttctgcttc taattccata ttggtcttgt ctgacatgat ttcaagaaga atgtcacctt
    18961 cattaacagg atcaccctct tgctttttcc attcgataat ctcgccttct tgcatgtcaa
    19021 caccgagctt tggcataata atttcaacag ccataatgat attgtaagga acgttcaaat
    19081 gcaatcagat gccttaacaa tcagcactgg ctaacataag cctgctaaaa gccctgcatt
    19141 tagctcatag ctagtgacta cgagctcgtt ccagatcctt tctatagttt taaagaatta
    19201 tcttttcgtt actttgtttc tgaaatatgc tctctttgca tcgcaggcca taaggcctgt
    19261 catcagatta gcagttcaaa tggattttcc atcaattttt tgagatcaac catgaattta
    19321 gcaccattca tgccgtccac cagacggtgg tcaattgtca gacacattgc catgattgga
    19381 cgtgcaacaa tctcaccatc gaccactgtt ggggttggaa tggttgcccc aatacctaga
    19441 atagctgaat taggctgatt aataattgga ttgaaggttt tggtgccaaa catacccaga
    19501 tttgtgatgg agaaggttga gcctgacatt tcggcagcct ttagcttgcc tccttgagcc
    19561 tttttgataa cgtccttaga agcaaggaca aactctgaga gacccatctt atctgcacca
    19621 tgaacaaccg gcacaactag cccatcatca agtcctacag caataccaag gttgacaaag
    19681 cgatgaagct caatatcatt agcatcatta atcaatgacg cattcatgta ttcgtgctct
    19741 ggcttcatca aggtcttaac aacggctaaa ccaatcaaat cagtaaagct aacctttagc
    19801 cctgttttag ccatgattgg gtcaatcagc ttcttacgca aggcaatcat ttcggtcatg
    19861 tcaatgtcat aattaagcgt aaaggttggt gctgtaaggt aggaatgtgt catacccttt
    19921 gaaatagcct tacgcatagc agacatcttc ttaatttcaa caccctctgg aagctcctta
    19981 gcaggctttt cttcagcaat agatgctttt tccacagcag gtgctgctgc gccaagcaca
    20041 gccaaaatgt cctccttggt aatcttgcca ccaatacctg ttccgaccac cgctgcaagg
    20101 tcaactccct tgtcggcagc tatcttacga gcaagtggcg ttgccttagg ctgagctcct
    20161 ttgaagcctt caacatcttc tttgtggata cggccctttg gtcctgttcc tggcacttgg
    20221 ttaagctcaa ttcccatttc tgaagctgct ttacgagctg ctggcgttgc gcgtaccttt
    20281 tctccgaagg ctggagcgtt ggcaactgat gctacctgag gcgctgttga ggctgcttct
    20341 ttcggtacag ttgttgtatt agcttctgct gatgttggta ctagaatttc agttgttttc
    20401 tcacttgaag cagtactatt atcaacagat tcacctgcag caccaatata gccgataacc
    20461 tcagtgacag agactgtttc acctgcctgg cgagtgattt ttagaagcac acctgaatcc
    20521 tctgcttcaa gctccatatt tgtcttgtct gacatgattt ccagaagaat gtcaccctcg
    20581 ctaacagtgt caccctcctg ctttttccac tcgatgatct cgccttcttg catgtcaaca
    20641 ccgagctttg gcataataat ttcgacagcc atatatttcc tttcgtttaa tctcgcagct
    20701 catgatctta agaccagata cagctgctga aaaaagggat actgttttat cagcctgatg
    20761 aagaaagcct ctaagctaag acttccttta ccatgctaat ttcccttatt aaccattttt
    20821 acaatagcag ccttgatttt agcaacatct ggtaagatag cttgctcaag aacacgtgca
    20881 taaggcactg gtacgtcctc actagcaaga cgcacaattg ggtgatcaag gtaatcaaag
    20941 gcttcacttt cagtgaccat tgctgcaatc tcaccgataa agccaccagt cttataggca
    21001 tcattaacaa gcataagctt ccctgtcttc ttaacagaat taataattaa ttccttatcc
    21061 agcgggataa gagtacgtgg atcaacaacc tccacattaa tgccgtcagc tgcaagctcc
    21121 tcagctgcct gaaggacacg ctctagcata cgtccatagg aaacaatagt tacatcagtc
    21181 ccttcacgct ttatatcccc cttgccaagt gggatataaa aatctggatc ctgattgacc
    21241 tcttcttttt taccgtacaa ggccttaggc tccatgaaaa taacaatatt gttatcacga
    21301 atagctgact ttaaaagtcc ttttgcttcg ttagcatttc caggtgcaac caccttgatc
    21361 ccaggaatat gcgtcaacca agcctcaaga gattgcgaat gctgagctgc agatccaatt
    21421 cctgagccag aagcaacacg aaaggttgct ggtgtgatca agccaccacc aaacatgtag
    21481 ttgttttttg ccccattatt aacaatcgca tcaagtgcaa tggtaataaa gtccataaaa
    21541 gtaaggtcaa caatcggacg aagccctgta attgctgaac caatcgctgc acctgcaata
    21601 gcagcctctg aaatcggtgt atccttgaca cgtttggcac caaattcctc aatcatgcca
    21661 acagaagtac caaagtctcc tccgtaaaca cctacgtcct cacccataag gtaaatcgtg
    21721 tcatctttgc gcatctcctc tgtcatggca agattgatag cctcacgcaa agccattaat
    21781 tttgtttctg tcattattat ctcctaatgt ttacaaaata gaattgtcaa tgttactgtg
    21841 aatagatttt tgctcgatgt gctagcagat cagctagtct acccaaacgt cctcaaaggc
    21901 tacagaaatg tctggatctg gactattttg tgcaaactca taagcgtcat caatttcttg
    21961 cttgacctgt gcttgaagcg catctaattc ttcatctgta gcaatgcctt cacctgttag
    22021 gtaagcgcga tacttaagca ttgggtcctt ttccttccac tcatcaacct cttctttggt
    22081 gcggtatttg ccggcatcgg cagttgaatg accaaaccaa cggtaagact caacctcaat
    22141 aacagcagga ccattgccac cgcgaacatg ctcaacagcc ttgctcatgg tttcataaac
    22201 tgccatcaca tcgttgccgt cctcacaata aaagcctgga ataccataag cctcagcacg
    22261 cgtgtagagg tgaggtgtat ttgtggcatt gttaatgctc atggaaatcc catagcggtt
    22321 gttaatgata aagaaaatca caggaagctt ccaagttgct gccatattga cagactcatg
    22381 gaaggagccc tcatttgttg cgccatctcc agaaaaggcc acaacgatat tgttggtccc
    22441 cttgtattgc tgtgtcaagg cagcacctac agcaagggca tagccacctc caacgatacc
    22501 atttgttcca tagtttcctt tttcaaaatc agccaagtgc attgagccgc cgcgtccctt
    22561 tgacacacct gttaccttac cggctagctc agccatcatt ttattgaggt ccatatcttt
    22621 agcaatagat tgcccatgcc cgcggtggtt tgaaaaaata atatcatcat aggtcaaatg
    22681 tgctacagcg ccaacgtttg ctgcctcctc accaactgag aagtgagtca tgccctgcac
    22741 aaatccacga cggacaagct tattaatacg tgaatcaaat tcacgaatac gctccatttt
    22801 aaggaacata tctaaatgtt gttctttaga aactgttacc atttcggcct ccatattatc
    22861 atattacttc ctaatcataa aacttttctt cacaatttgc aaggatttta atcgctttct
    22921 ttgtgactat aaaagctttt ttaatgcgtt ttagtttgtg atttcacaaa ctatattgtt
    22981 atagcatctg ttacatttat atataacaga ttgaaaaatg agtcagtgat tattcaggaa
    23041 ggccaagcac ttattgactt tgatagtcag aaatatcatc actctttaag aggaaaatag
    23101 gatctaaatg acctgtttct tctagcacaa tcatgaccac ctgttaaatg agtgctttgc
    23161 ttggctccga taggtgcaaa acaaactaaa aatcgcatca ctaaaaatgc ctgatttcac
    23221 ctgaaaatca gacatttaaa agctttaaga cattagactc aggctctaat tataatcctc
    23281 taagaaaagc ctgctacctt gcactaccca agaatagcaa ggcaatttca ttatctcacc
    23341 aggctactcc agctgtcctg caatgtcctc ccactccagc agcaaggtct cctgtttctg
    23401 attaagctga tccaactctt tttgccagtc tatcagttga gtcgtatcat ttgatactag
    23461 catttgagct tctatagcct tagcctgtgc ttctagccct tctaaggtct gctcaatctc
    23521 ctcaaagcgc cttgttaagc gacggtattc cttttggctg gccttttgaa gctgataatc
    23581 agttacagca gcttctgcta catcagtctc tactacgtga tctgcagcag ctagacgggc
    23641 taattcctcc tgctctgcct ttttttctac ataatagtcg tagtccccca gatagagtgt
    23701 tgagcctgct tcagttattt ctaaaacctt agtggccact cggttgataa aatacctgtc
    23761 atgactaaca aacaacaagg ttccatcaaa gtcaatcaag gcattttcta gaacctcttt
    23821 gctatcaata tccaggtggt tggttggctc atctagaatc agaaaattgt cctttttcat
    23881 agataatttt gctaagagca gccgagcctt ttcgccccca gatagcatgg ccacagactt
    23941 tttgacgtcc tcaccagaaa agagaaaggc acctaagcgg ctgcggatct caagctcagc
    24001 tgtcgttggg aaatcacgcc aaagctcctc caatacagaa ttactaccag tcagatgaga
    24061 ttgcgtttgg tcataatagc ctgtttcaac attagtccca taatggcatg tccctttaat
    24121 caaaggaatc tctccaataa tggatttgag tagggttgac ttgccaatac catttggccc
    24181 aacaatagcg attgcatcta acctacggac atctagacca attggctcag ctaaaatgtg
    24241 gtcattgtag ccaatagctg cgtctgtcac ctgcaaaaca acatttcctg agggcttatc
    24301 aatctgaaaa gtcatactag ctgatttgcg agagctgctt ggcttgtcta agcgttctag
    24361 cttttctagc tgcttgcgtc ttgcctgagc acgcttggtc gttgacgctc gaacaatgtt
    24421 tttttggaca aaatcctcta gcttagcaat ctctttttgc tgcttgtcat aatgcttctc
    24481 ttctgctgca agcttttcag cctttaaatc aataaagcgt gagtaattac caacatagcg
    24541 gtctaagcta tttttagtca gatcaagtgt gatggttgcg accttatcca agaaatagcg
    24601 gtcatgactg acaatgatca aggctccctg ataatttgcc agataatgct ccagccaggc
    24661 aatggtttca atatctaaat ggttggtcgg ctcatcaagc accaatagct ctggcttttc
    24721 tagtagcatt tttgccaggg ccaaacgggt attttgccca ccagaaagct ctgagatttt
    24781 catttcccac atgctttcgt caaacttaaa gccatttaaa atagctcgaa tatctgactc
    24841 ataggtgaag ccatttcgca agcgaaagct ttctgacaac cggtcatagt ctgacatgag
    24901 ctggtccaga gcttgccctg atcgactggc catatcagcc tccatttgcc ttagtcgctg
    24961 ctcatcagcc ctcaattcag caaatacctt tagcatttcc tgataaatgg tcttgtcaga
    25021 ctcaaatcgg ctattttgtg ccaaataaga tagggttaag tccctttttc gattaacctc
    25081 accgctagtt ggctcttctt ctccaactaa aatcttaaga agggttgatt tgccagcacc
    25141 atttggccca accaaggcaa tgcgatcacg ttcaccaacc tgcagcgata ggttttgaaa
    25201 aagcacctct cctgaaaaag agcgctcaat gttatttcct tgtaatataa tcataccctt
    25261 attgtagcaa aaaaatgccc tttttggggg cacttttagt tattttcaca ggtaagataa
    25321 gactcatcaa caggctaaag acataagcct taggctaaca tcgcttatca cccttagtgg
    25381 tatttatctg atgagacaaa ctgctgcttg aaaaaccagt gggttgacct gttagcgtat
    25441 ccaacaatcg caccacctgc tcagttatgc ttgaaatact attagccagt gaggaatcac
    25501 tatggttcga ataataaatc aaaccaaaaa taagcaatac caatactatt agggccttca
    25561 agcaacctct gataagctgc cagacaagct tcagcagaag ctttgggagg cataagagga
    25621 tagtcagtag ttttttcatc ataataagtc taaattcttt cgtttaggat agcctttctt
    25681 ccttgtggta agcaatcggc agccaatcta atagggcctc tagctgctga ttccaataat
    25741 accattcgtg cctgccatga tccttacgat aatcaatagt caagccaagc cttctcaact
    25801 cagcaactgc cttttcattg gcttcaaaca aaaagtcctc atagccacac caagcgtata
    25861 gctgggtttg accatcactt tctgctgcta tacttgtcaa ataatgcttt ttgatatcag
    25921 gagcattcaa atctccaaaa acaccctgcc aataaggcag ctcacttata ccttgctgta
    25981 atagcatttc cggcgaaaaa tgcaaggccc cagaaaagga agcagcatag gaaaagcgat
    26041 tgctttttaa ggcccattta aaggcaccat agcctcccat tgacagccca gcaacaaatg
    26101 ttttttcacg cttagtggtc atattaggaa agaaagaagc taatagccga ggaagttcct
    26161 ctgcaatagc ttggtaataa ttcataccgt aggtggtatc ggtataccag cctaaatcag
    26221 tcgatggcat cactacgatt aaattggtat ggcgaagcag cctttcaata ttagtccgct
    26281 tttgccagga attttcattt cctcccatac catgtaacag ataaagaact ggaatatctt
    26341 ggtcgccttg ctcttctggg ctaagctcag actgatcagg gtagattacc ttgacatgcc
    26401 tttccatagc caagacctct gaatgatact caatgctaat acttgccatc agctcacctc
    26461 ctttttaata tcaccaaagc ataaggaaag cccactctta ggacctaaag gccagattct
    26521 atttgaccag cttttaggca gggctgtatc tgtattaacg gacctccatg acgaccggaa
    26581 gaatagctgg ccgacgcttg gtctgctcaa ataaaaatct tgagagctcc tctctaacag
    26641 agcctttcaa ttcactccaa tcaaaatgat ccccttgcag ataattacca actgttgtgt
    26701 tgaccaattc agcactttct cgtaaaatat ctctgctctt tttcacatag acaaatccgc
    26761 gagtgttgac cttagcctta gagataatac gtttttcttt tttagatact gtgatcgcaa
    26821 caataaaaat accgtcctct gataagacct tacggtctct caaaacaata ttgccaacat
    26881 caccaatggc atttccatca atcatcacat cactagcagg aaccgcaccc tcgtgtaaga
    26941 agccatcctc atcaagcacc atgatgtcac cacgcttcat aatatgaata ttctcaggta
    27001 gcataccagc ctcctcagct aaatgagcat gagcagctag atcgcggtat tcaccttgaa
    27061 tcgggaacag gtattttggt ttgacgagat taatcatcag ctgcaggtca cgcgcattgg
    27121 catgtccaga aacacgtaaa tgctgcgtga tgagcttaac agatccacct gctttataga
    27181 taaggttttc aacacgagca accattgctt ccttggcagc gcttggcgtt gtgacaatgt
    27241 aaaccagatc tccgtccttg atttgcacgt ggcgatgacg ccctattgcc attttctgta
    27301 ggctattaat cggctcaccc atacgtccag cctccagaac aatcaattcg tgatcctcaa
    27361 acttagacat atcctttggc ttgattaata gcttttcatc agcaatcact agctttttaa
    27421 gacgaagtgc tgttctgaca atattttcag cgtcagtacc tgtcagtacc actcgcctgc
    27481 tataggctgc tgcagaatca aagacctgct ggatacgaac aagatttgaa gcgacagctg
    27541 caatgataat ccgcccgtcg gcatgagcaa tcaccttatc catctcctcg ccaacctcag
    27601 cttcgctggc agtctgctca ttgcttgtgg cattggccga gtcagctaat agagctaaca
    27661 ccccttcttt tccaatgtct gccaagcgag ctaggtctgt ctgatagccc tcacgcgaag
    27721 cctggtcaaa cttgaaatca cctgtataga caatattccc cttatcggtt ccaataacca
    27781 cgcctaaact ttcaggaata gaatgtgttg tcttaaagaa ggaaaccaag ccatctttaa
    27841 attcaatttc tgtgtcactg tcgaccacat ggaaattctt aaatctcttg gtgctattat
    27901 tggccttgac aaacaatttt gctagctcga tggtcaattc tgaaccaaat actggcactg
    27961 gaacctccgc caacaggtaa ggcaaagctc cgatagcatc agcatgccca tgacttaaaa
    28021 agactccttg aaccttgtcc ttgttttcaa ttacataatc aagacttgga attaccaaat
    28081 ctacacctag ctgttctgtt tcagggtatt tcaagccagc atccaaaatg aacatggaat
    28141 cgttaatctc tactagatag aagtttttcc cgtactcacg tacgcctcct aatgcaataa
    28201 tgtttatatc agtcatgata ctcctttttt tatattagtt attacaaacg gtccttactg
    28261 ggtaagtcga attactgtct tgcagctaag ctgcactctt ttacagtata tcatatttta
    28321 gggcttatta cctcaaattg ccttgagact ttctcaatct tttcaatcga ttatcgaaaa
    28381 agccaatgga aggctttcat tccaatggct tttagggcgt ctattttagt caaaaagctg
    28441 gtaataatca gcaatagtca tttgagattt tctcttctga tcaaggtctt gaatgatttt
    28501 accatttttc atcacaatca agcgattacc gtagttaaga gcgtcctcca tgtgatgcgt
    28561 tatcattaag gctgtcaagc gatccttagc tacaaaatca tcagtcaagg ccatcaaggc
    28621 ttggctggtc ttagggtcta gcgctgcagt atgctcatct aatagtaaaa gctctggtct
    28681 ttttagggtt gccatgagta agctaagggc ctgtctttga ccgcctgaca agagaccagt
    28741 cggagtctcc agatgatttt ccaagccatt tccagctcgc ttgaccaagt cagcaaagtc
    28801 tgccatatag tggctaatcc tgcgtgatga caagcctcgc ctttcccctc tttgccttgc
    28861 aatcaaaagg ttttcagcta ctgtcattcg aggtgctgtt cccattttgg gatcctgaaa
    28921 aacacgtgat aggtagctag ctcttttttc tgctggcaga tgcgtcacat catgtcctaa
    28981 aagcttaatc tggcccttgc ttaaaaagag cgtcccggca atcacattaa aaagggttga
    29041 tttaccggca ccattcccac caagaatcgt caaaaaatca tgctcataaa tggtcaagga
    29101 aacatcatct aaaatagcct tagtctcatc aaaaccatta ttgacttcga cagtagcatg
    29161 gatcaattca ataatttttc tcatcgtgat aagctagcct ccttaataat tgcttttttt
    29221 agtacaggta ccatcaggca aagcgctaat ataatggcac taaatagctt aagataattc
    29281 gtattaaagc caagggcaat gactgctgag attaaaaatt gatacaggat agaaccaacc
    29341 acaatggcta tcaggcgctc aagcagggtt aatcctgtcg aatataaaac ctcaccaaca
    29401 ataatactcg caagaccaat cacaatcaca ccaatcccct ttgaaacgtc agcatagcca
    29461 tcttgctggc taaccaaagc tccagacaaa gctatcaagg cattagagat tgctaagccc
    29521 ataagctcca gacgatcagt atgaatccca aagctcttag ccatatcccg attatctcct
    29581 gtggcaatat aagcctgacc aatattggtg taaaggaaat acattaataa cgatatcacc
    29641 aaaaccacca caatcaagcc agctaccaac acattggtat cagctgcaaa gggaaggtag
    29701 tcctgaatac gcttaaggtc atgcaagccc aaattggccc ttcccataac cataagcata
    29761 atggaatggc aggaggtcat gactaatatg cctgcaagaa gcgtaggtat ctttcctttt
    29821 gtgtataaca ggcctgtcgc tagacctgcc aaagcacccg ccagcatagc agccagagta
    29881 gctaggatag gatttaaacc gagattgagc agggttactg ctacagcccc ccctagagga
    29941 aaggagcctt ctgttgtcat gtctgggaaa ttcaatattc taaaggtcag gtaaatcccc
    30001 aagccaagaa ttccccataa caagccttgt gatacagatg aaataatcat atgagctcct
    30061 tttctattgc ttacctgtaa ggtcagaacg cttcagcagg tcttttgaaa gaacaagacc
    30121 taaatccctt gccaccttta catttaaaaa tggcttaccg ttatcaacta ccttgacagg
    30181 aacctctgat acctcttttc cagccataag ctgcagcacc tgcctagctg tctcaacccc
    30241 taattggtat tgactttgtg aaatagaagc aaggctgcct tgttcaacca ttgtatcaac
    30301 acttgagtag accggaagct gtgctgcatt tgaagcagca accaccgctg aaaaggcact
    30361 ggcgatggta ttatcctgag ggataaaaac agcatctacc ttctcagtca tcacagacat
    30421 ggttgtggtc acctcatttg ttgagggaac agcgtaggct agaacctcca agccttgctt
    30481 ttctgcaagg gctgtaaagt ccttgacctg tgatattgaa ttgtcctcac tacttgcata
    30541 aaggacaccg acccttttga cctgaggagt catctccttg atcagatcaa ccgtttgtcg
    30601 aacaggaacc ttatttgata agccagtaac atttgcctca ggcctgtcta agtgcttaac
    30661 taatttagca ccaactggat cagaaatagc tgacatcaca accggaatag tcttggtcgc
    30721 tgctgctaat ccttgagctg caggcgttgc gatgccaaca acaatatcgt ttgttttgac
    30781 cagctgcttg ctcatggtct gaatcttact ttgatctcct tctgcattca taagggtaat
    30841 gctgaccttt tgctctggct gatgatgctt ctttagctcg tctttaatgc cctgtgcaat
    30901 ctggtcaagc gcctcatgag taaccagctg caatatacca accttaacca cacgcttgct
    30961 ggctaactgt ggctgttttt tgccctcttt tagcactagc gaagcagcaa ccattaaaaa
    31021 gagtgcaatg actgttacga taagaccttt atgtttcatg ttctacctct taatttccat
    31081 tcttattccg ttgctaacat ttagagtact cacaaaaaga aaaagcgctt agtaatcagc
    31141 tactaggcgc ttttttgaaa tccaatgtca gcgcatagat acctttttag aagtactcta
    31201 aaagtcgtat ctatgctaat ccataaacac aactttatct atgccagctt tgccaattta
    31261 tcatatgctg tgtttgcttc atcttggatt tcctttctcg tttttttaca ttataaccta
    31321 aaagctcaaa aatacaagag catttgaaca tatttttcca ttattttttg tggtataatg
    31381 aaagaattag aactcaggag ggagaaacca tgtcatttga cggctttttc ttacatcatt
    31441 taactcaaga gctcaaccat agtattgtta atgggcgcat tcaaaaagtc aatcaaccct
    31501 ttgataatga gttggttctg actatccgta accatcgcca aacttacaag ctcttgctct
    31561 cagctcatcc ggtttttgga cgcattcaac tgacccaaac agactttcaa aatcctcaat
    31621 ttcccaatac ctttaccatg atcatgcgca aataccttca aggagctatc attgaaggct
    31681 ttgagcagat tgataatgac cgcatcatcg aaatgaccgt ctctaacaaa aatgagattg
    31741 gcgatgccat aaagacgaca ttgatcatcg aaattatggg caagcacagc aatattattc
    31801 tggttgaccg tcatgaaaac aaaattatcg agtctatcaa gcacgtcggc ttttcccaaa
    31861 attcctaccg gactatttta ccaggctcga cctatatcga gcctccgaaa acagctgctg
    31921 tcaatccttt tacgatctca gatatcgctt tatttgaaat cttacaaaca caggagttat
    31981 ctgctaaaaa tcttcaaaag catttccaag gtcttggccg agataccgcg caagagctat
    32041 ccagcctctt gacaactgat aagctaaaac ggtttagaga cttttttcaa agacctagtc
    32101 agccaagtct aactcagacc tcctttgctc cagttgcctt ctcaaacaca ctgaagacct
    32161 tccagaatct atctcagctg ctagattatt attatcatga caaggctgag agagatcgta
    32221 tcaaccagca ggccagtgac ctgatccacc gcgttcaaaa cgaattggaa aaaaatcgca
    32281 gcaaactgat taagcaagag gctgagctac tagccactga aaatgcggag gactttcgcc
    32341 aaaagggtga gctcttaaca acctatctga gcctggtgcc aaatgaccag gattcagttg
    32401 agcttgataa ctactatacc ggccaaaaaa taaccattgc acttgataag gcgttgactc
    32461 ccaatcaaaa tgcccaacgc tattttaaaa aatatcaaaa attaaaagaa gctgtcaagc
    32521 acctctcagg tctcatcgct gacacgcaac aaaccatcgc ttattttgaa agcgttgatt
    32581 acaatctatc tcaggcaacg attgatgaaa ttgaggacat tcgagaagag cttattcagg
    32641 ctggctttgt gaaaagccgt aagcataaca agcaccacaa gcgaaaaaag ccagagcagt
    32701 acctggcttc agatggcaaa acaattatta tggtcggacg taacaatctg caaaatgagg
    32761 aattaacctt taaaatggcc aaaaaaggcg agctctggtt tcatgctaag gatattcccg
    32821 gcagccatgt gatcattaag gacaatctaa gcccaagcga cgagatcaaa actgatgctg
    32881 ctgaattggc ggcctattat tctaaagcaa gactttccaa tctcgttcag gtggacatga
    32941 ttgaagccaa aaagctgcac aagccaagtg gtgcaaagcc tggctttgtc acctatacag
    33001 gacaaaagac actaagagtg acacctatag aaagcaagat tcaagccatg aagtgctccc
    33061 cttcagcctc ttcctcatag gactacagca ataaagataa aaaaagctac agcctcacac
    33121 ttggagatag gtccagtctt aaagctgcgg cttttttatc attacttgtt aatcatctct
    33181 caaatcatct aagaagcctt gcatatgaat atcatctgga acctgctgca aatacctttt
    33241 tgcctgctta actgcttgat cagtatagcc gaattccctt aataaataag cataatcctg
    33301 taaaaagtca ggattttctt ttaggtctcc ttcgatatct ttatagatag tgagggcttt
    33361 ttcttgctgc tccagagcct gataggcctt ggcaaggttc catttagtta gcacatgatc
    33421 aatctcttcg tgctcaagag caatgacctc ctcaaaacgc tccatatcca agtacaggct
    33481 agataagcgc atgatgacct cttcatcatc aacagctact tccttggccc tgagcaaata
    33541 ctgctctgag ccagctgaat catgcaattc aaaggcaagc tgtgaagcaa gtagcagcaa
    33601 ttgagcgtca aaggcatttt tccgcagacc ctgctgaact aggcgtaagg cctcttctgt
    33661 ccgatgctcc tcacgcaagc tcatggcata ggggtactcg tagcctaaaa agtctgcatt
    33721 catcgtttct aattgcttga aatagagatt ggccttttgg taagcagcct gatcatataa
    33781 aatcgccgcc agctcaaaca ctgtctcatc gtcatactca atgacaaggg ccttttcaag
    33841 aaattctaca gcagcttcaa atttccctaa ataagcatag gcacgcccta tgcgctggta
    33901 ggttgagata cctgtcagct caagaatgtg acgattatca agcctagcat attgctcaat
    33961 agcctcgcta aagtgctcca gagacatctc gatttcggct aagccaaaga tcactatcgg
    34021 ctcctgactc aattcagctg cttgaagcag cttctcacgc gccacatcag ttagcccctc
    34081 caagtcataa aggtcagcca tgacgagcag agcagacaaa taatcagcac tatcctctgg
    34141 aatcctatca aggtacataa aagcctcttc catggcatta tcctcagctg caatctgagc
    34201 aagattaata ttgacctctg gataagcctc acagacctgc aaataaatcg tcttagcatg
    34261 cagtaaaaaa ccaatactct ctaggtattc tgccaaagcc agcaaggtct cagcatcgtc
    34321 ctcctgcaag gctctttgaa aatagctttc tgcctgctct aaatcctgtt gctctagtga
    34381 ggcaatcatt ttttcactat ttaacatctt cagcgaccct ctcagcttct gtaggctctt
    34441 cctcatacag gcctgtaata tccttgtacc aatcaaatag ctccttcaca acaaccttaa
    34501 cagaagcata aactggaatg acaagaaaga caccccagac cccaaacatt gaccctgctg
    34561 tcaataataa aaacataatc gtaatcgggt gaatgctcag cttgtttcca agcactagcg
    34621 gcgcgacaaa gcgtccttca atcgtttgtt caatgacaaa aataatcaac accttgatca
    34681 gcatcaaggg cccttgcacc attcccataa taaccacagg aatcatggct aaaaagctcc
    34741 ccagataagg aatcatatta agaaagcctg caataatacc aaaggtaata gaatagttca
    34801 aaccaacaag gctaaacatc actgaaaaca tgagaccaac cacaatcgca acggtcacct
    34861 gtccctgcac atagccagat aattgcttgt tgatttctcc taagacacgt gccataggct
    34921 ggcgcagctt aatcggaagc acattgacca aaccattttt catatggtca ctgtcacgca
    34981 gaaaataaaa gagaataaaa ggtgacatga tgattgcaac agtaatacgg gcaatagctc
    35041 cagcaaaatt tcctgcccaa tcaatagcat ttttagagaa gctttgcgca taatctagag
    35101 ccttttggct catgctagtc agcatatcct gcaggttgga cctgtagcta accagccatt
    35161 cgttttcaag tagcttatta gcctctagat tgaccttggc aacatatttg ggaaggtctt
    35221 cgacaaagct ccttagctgg tcttgaatca tagggataaa gccagaaata gcccagaaaa
    35281 ataggagaat tactaagcca aagacaataa aaatagaggc tgtacgattt ggacctagct
    35341 tctcaaccat atcaactaat ggcttggtca aataatacag gatggttgag ataaccagcg
    35401 gcagcataat aatggccaaa aatgacaaga tcggtgtgaa gaggaaggat atttttgtaa
    35461 agacaaaaat agtcagaaaa accagcagcg tgattaacaa aaccatcacc gcctgattat
    35521 ttaaaaacca tttgtaaaat agactatcat gatgattagg cttagaatgc aatgacatta
    35581 atggtatcgt cctttcttaa ttgtggcatc attctgatga gagcttttag gttagttgac
    35641 ttaataaaag gtgactgttt tttccaccag cttgttgtgg tcatcatacc taaatttagc
    35701 agaaaaaaac ggccggtctt ccaatatcca tttgaaaatg tcgtagtctc cctcccaagt
    35761 tggcttttcc agcacctgat catagggaac ccattctagg gtcccttctc tggactcctc
    35821 atcagcaatt aagtcacctt caaagtctgt caccttaaac acgtaagtat accaatcatg
    35881 ccctggtgta aaatcaggaa aggtaatcac tcccttaaag tccattgctt ttaccagcag
    35941 gtgagtttcc tctaaaattt cacgtctggc acagtcatca ggagattcgc ctggctctaa
    36001 tttgccacca actgaaatcc acttaccttg gtgaacatca ttttccttct tgttgcgatg
    36061 cagcagcaat aaagcctcac cgttatcaat ataacaaatc gttgctagct tagtcattca
    36121 tacccttcct ttgtttagtt gttactatta taccaatctc tgagaaatat gccatcattt
    36181 tatcatttaa gcacatcaaa caagaaaacc acaatcacta caactcttag ccctgtacta
    36241 gcaaaaaagc cttgataagg caacgtctgc tgactcatca agacttatca ctatttaacg
    36301 aatcacttcc tgtgtcttag cgtaattggc ttcaactgct tctttttcgg aacgccacca
    36361 atcctgatga tcagtatacc attggatcgt ttgctcaagt ccttctgaaa aatcagtaaa
    36421 ctgtggctcc cagccaagct cctgacgaag ctttgtcgaa tcaatagcgt agcgtaaatc
    36481 gtggcctgca cgatctgtca catggtcata agcgtcctta ggctgcccca ttttatccag
    36541 aattaattcc agcacttcct tattattttt ttcaccgtca gctccaataa ggtaggtctc
    36601 accaatacgt cccttggtca aaatagccca aacaccagtt gagtggtcat tggtgtgaat
    36661 ccagtcacga acgttctttc cttcaccata caattttggc ttgataccag acaagatatt
    36721 agtgatctga cgaggaataa atttctcgat atgctggtag ggaccataat tatttgaaca
    36781 gtttgaaatg gttgccttca cgccaaagga gcgaacccag gccttaacaa tcaaatcaga
    36841 ggctgccttg gttgatgaat aaggtgatga cggattatag ttagtctcag cggtgaattt
    36901 ttcacctggc ccctcaccat gacctggcaa atcctcacgc agtggcagat ccccataaac
    36961 ctcatcagtg gacacatgat ggaagcgaat atcatattta cgagccgcct ctaagagtgt
    37021 ataagtccca acgaagttcg tgtaaataaa tggacttggg tcattgagcg aattgtcatt
    37081 gtggctttca gcagcatagt gaacaatagc atctgcctta gcggccagct tatctaccaa
    37141 ttcagcatca gcaatgtcac cgacaaccag ctctacacga tcacccaaaa tctcctcaag
    37201 gttagcacga ttgccagcgt aggttagctt atccaaaaca gttatgtgaa cctctgggtg
    37261 atggttgtaa acatagtgta cgaagtttga accgataaag ccagcgccac cggtaacaat
    37321 aatgtttttg tattcagaca ttttttattt tcctttgttt tcagctatca gcactcaaaa
    37381 tgcagcttaa tcagacaggc aagctcagcg accagtaaaa acagcagtta agctgcctca
    37441 cttcattgct tctacaatcc gtaaggtccc tcctgtcagg aggacacaag gacagctcca
    37501 tcaagaatca tagcttattt caaatgctca ttatgataaa tcttcttgtc tcaaaggctt
    37561 aacggcctct aggaagggat ggcttttatc tgcttctgaa acctctgcct tttcaagact
    37621 ttcccacgca atcccaaggc ttgggtcagc ataattaaca aaggcatatt ttggcttgag
    37681 ctcaagcgcc caataatcat tgaccagata ggtataagcc accttatcag tcagtacttg
    37741 aaagccatta gcaacacctc gagggacaaa aatccccttt gaagcatcaa tgactgtttg
    37801 ataggtatgc ccaaagctat caccctcacg aagatcaacc caagctccaa gaaccttacc
    37861 ctcatcagca acagagatgt acttgtccca aggctctgca tgcaggcctc gaagcacatg
    37921 cttgcgcgaa aatgaaatat tgttttgcag cttacctgcg gcaaaaaact gctcaggaaa
    37981 gcctagagga atcatttttt ccttttgaaa attttcctta aaccagccac gattgtcccc
    38041 tcgaacaggg atatcaaact ccaaaagtcc aggaatggct tcaatttccc gacaggctaa
    38101 ggctttatca aaaaattgtt ctgtcatcaa gcttctccaa tcaaccgcag caggtactgc
    38161 ccgtattcgt ttttcttaag cgactgcgct agctggtaga catcttcttt agtgatataa
    38221 cccatgcggt aggcaatctc ctctaggttg gccacctgag cgttttgcaa gcgttgaact
    38281 gtctcgatgt attgggcagc ctccagcagg ctttcatgag tgccagtatc tagccaggca
    38341 aagccacgtc ccatcaactc aactgataga tcgccacgct ctaaataggc tttgttaaca
    38401 tcagtaattt caagctctcc acgagcactt ggtttaatgc ttttagcaat ctcaaccaca
    38461 tcattgtcgt aaaaataaag gcctgttaca gcaaaatgtg acttaggaac tgccggcttt
    38521 tcttcgatag aaatggcatt catctcatcg tcaaactcca caaccccaaa gcgctccgga
    38581 tccttgacct gataaccaaa aacagtggcc cctttttcct tagctgctgc cttttggagc
    38641 attttcgtaa ggccgtttcc atgatagatg ttgtcaccta aaatcaaggc aactcgatca
    38701 tcaccaataa actcctcacc aatgataaag gcctgagcta agccgtcagg acttggttgc
    38761 tccttgtagg acaagctaat cccaaactct gatccatcac ctaatagctc ttcaaatctt
    38821 ggaagatctt ttggagttga aataatcaaa atgtcccgaa tacctgccaa catcagtgtt
    38881 gataagggat aataaatcat tggcttatca taaattggca tcaattgctt tgaagctgca
    38941 cgagtaagag ggtacaagcg tgttcctgat cctcctgcca gaataatacc tttcatcgta
    39001 gctctcctca ttttataata cgtcactatt ttatcatttt ttaaaaacag tgtcactttt
    39061 tatcattaat ccgacgaata taatgatgaa tcgggtattg actagtatct aagctagctt
    39121 tttgccccaa aagcagggca accagctgct gagcaatcaa aggacctaca gtcaagccag
    39181 aagagcctag accgcttgca gcgtaaacac ctggtagctg aggtacctgc ccaaaaaatg
    39241 gggaaaaatc tctggtataa gcccgaatgc ctacgcggta agagatatca gaggcagcac
    39301 tcagcttagg gtaataggtc aaggcctcct gctccaaggc ttctaaaact gctaaatcag
    39361 gctcaagatc atagccctta tcattttcat gactcgctcc tacagatatc ctaccatgct
    39421 caaaggggat aatatccagc tccccttctg gcatgaccac tgcgtagtta tctgtagcca
    39481 cattcgcaat atgataatcc attaactgtc ctttttgcgg tcgaatatcc acttgatagc
    39541 caagcggctc aagcaattct ggcagccaag caccagcggc taaaatcaac cgatcaaaga
    39601 ctataccatc aacgagatag ccttgctttt ctatgcttat gctaacacgc tttttaacca
    39661 cctgatagcc actagcttca agcaagcact gacataggtc tgccccatca acacgtgcag
    39721 ccccagaagc ccataccagc tgctcaaaac cctgtaaatc aggaaaatca gccctaatgt
    39781 ccgaacgaca ccttatcgcc aaatctccaa tcaaaggtga ctcttgcttt cgtttattag
    39841 ccagctggta gagctcctct agcttgttct cattcttttt taataaataa acaccagtct
    39901 gcttataaaa atgtgtagaa agcccctctt tttgcagctc cttgattaag tcctgataac
    39961 aatctgctcc taaccgagcc agctgatacc aagccttatt ccttcttttt gaaaaccaag
    40021 ggcagataat gccagcggct gccttagttg cttgaccatt accatcatca aaaatagtga
    40081 cctgctgata cccttgtttt tttaaataat aagcggcgct tgaacctaca attccagctc
    40141 caataattgc tatagttgtc attgcctttt ccattctatc atactgctta ccaagcataa
    40201 gccatactca gtcatgctat agatgactaa agggatttgt tgacaccttg ctagccataa
    40261 tggttacttg ccagccttcc tcttttttcc aggtctgcat cttggcaact agctgatcaa
    40321 taaataagga ctcgatatgg tgtcccggat caatcgctaa caagccttct gttatcatct
    40381 cctgtgcaac atggtaataa atatcaccgg taatatagac ctgtgcccct ttagcaagcg
    40441 ctgcctgata aaattcatca ccactgcccc cacaaatagc cactcgcgaa atcaaagggt
    40501 cttgaccagc atatcgaaca agccgaaccg catcaagccc aaaggctttc ttgactgtaa
    40561 gtcctagctc ctccaaactt tgctctgcta catttccgac acgtccaata ccatacccat
    40621 cttgcgtctc aaccaataca tctgtctgat caatgcccaa cagctcacaa aaccaatcgt
    40681 tgagcccatc agggacaata tctatattgg tatgactgac atagacagaa atatcatgct
    40741 tcaccaggtt aaggacaata tctcgctgtg gcgaagagac caagtccttc aagcccttaa
    40801 aaataggagc gtgcttggtg ataatcaggt ctaccttggc cgcaatggct tcggcaacgg
    40861 tattttctct cacatcaagg gtgatcatta cccttttgac ctccttatcc aaggagccaa
    40921 tttggaggcc acacacatct cctgacatgg atagctcaag cggacaatag ctttcatatt
    40981 tttcgatgat tgttctagct ttcatggctg atgacctcct caattgcttt tattttttga
    41041 gaaatgctag cgcgttcagc agcccttgct tctggcacac aagatagggc atagactagc
    41101 ttatcaagct ctctttgcca tttagccaca aagactgatg acctttcctg agacaagaag
    41161 ggaccaaagc gctgctcatg atctgttaga ctttgttgac caggctctgc aacaatgatt
    41221 tcataatatt tgccattttc tgtcataatg gtctcagcaa taatcctaaa agcattggca
    41281 gatagccagg cacgcagctc atcctctcga ttattgggct gtaaaatcaa acgcccgacc
    41341 ccctgcagct tttccttacc agccgctaaa atatcagcta ttaagcgccc tcccatgcca
    41401 cagatggtta tgcagtctac agcatctctc acctcaaagg cagctaagcc atcagccagg
    41461 cgtacctcaa tatgctctgt caagccatat tgcgacacat tttttaaggc tgatgcaaac
    41521 gggcccttga ccacctcacc tgcaatcgcc ttttgaattt gcccagcttc aaccaaaaaa
    41581 ataggaagat aggcatgatc acttcccaca tctaacagcc tagcaccatc aggaacatag
    41641 gctgccacat ggcgtaaacg ctttgataaa tgactttcca ttttcttaat ccttctaaca
    41701 actaatcgta tcactattat agcaaaatac agaccaatta aaaagaaagc ctcatcagac
    41761 cttcttttta ccgtaggtag tcttgtaata gctgcaatag ccttgcaccg ggcagctatc
    41821 acacttagga tgtttagcca agcagtgata gcgtccaaaa aagatcaaac ggtggtgggt
    41881 gatgatccaa tccttcttag gaagcttggc catcaaatca gcttcaattt cagtaacatc
    41941 ggcatctggg gcagaaatgt tcaagcgctt ggcaatcctt gacacatgcg tatcaactgc
    42001 gattgcagga acaccgtaaa cctctgccaa aactacatta gcagtcttac ggcctactcc
    42061 tggtaaggat tcgagctcct tatgggtttt tggtacctga ccatcaaact gaatcagcag
    42121 ctgctgagct gtcttgatga tattttttgc cttattttta tacaagccaa ttgtccttag
    42181 atgatcctca acatctgaca catttgcctg agccaaatct gaaagctctg ggtagctttg
    42241 ccacagctta ggggtaacct tgttgactgc cttatcagtt gtctgagctg ataggataac
    42301 cgcaataaga agctgaaagg gcttttcttg gtcccaattc agctcgccct tagcctctgg
    42361 aaacatctca ccaatgattg atagaacctt ttttaaccgt tctcttccta tcctcattag
    42421 ttactccaaa ggttcatcgc cgcaagaaaa tcatctgaaa ccgtcacttc agacgccgtc
    42481 atatcctctc tggcacgctt tttttcctca agctgcctga ggcttgtaat cccctccttg
    42541 cgccagtttc ttagaatagc ctgaatatat ttccaattgg ttttcccatt aaagaccgct
    42601 tctctcagcg cctcacgtac taaatccaga tctgtttggt catcatgaac ggttttttct
    42661 aaatcctcta gctccatcgg actcaaaaaa cgccccagct cacgctcaaa ctcatcaaca
    42721 agaagcttca attgattggt attttgctgt tcaagctcgc tcttttcatc acgcgccagc
    42781 agctggtcta gagtgactag tacaggacta gcatcaaaga tgatctcaat ctctccagcc
    42841 agctctatgg tcttcatgtc taataacccc tgactggtca aggaagaaat agccttattc
    42901 acctctgcta cagacttacc caaggcatta gcaatctgac taggcaccaa ctcgtcaagc
    42961 ctagtcgtat tttggagata gaaaaactgc caaaccaaaa aatcgtctga gctcttaaaa
    43021 atatccttgt aatgaaacag taaggcagtt ggaaggacca aattgccaga ctgataatgc
    43081 tctaaaaaac tcataattcc cctgccaaac gaaatagccc aacccagctt ttgatcagtg
    43141 ctgtcattaa caagcactga ttaaccagga aaatgcatca ataccttgca atcgtaatca
    43201 ccaatagcct gacgaccatt caagccgtcc agctcaatca gaaaagcaca gccagcgaca
    43261 atgccgccca gcttttcaac cagatcaata gtagccttta cagtaccacc tgtcgctaat
    43321 aggtcgtcca caataaggac acgttggcct ggcttaatag catcagcatg catggtcaag
    43381 gtgtctagac catactcctt ttcatagcta gcagaaatca cctctcttgg caatttaccc
    43441 ggcttacgaa caggagcaaa gccaattcct agctcaactg cgaccggaca gccaataata
    43501 aagccacgag cctccggtcc aacaatcatg tcaatgtcct tatcgcaggc atattgcgca
    43561 atctcacgaa tagcatagct gtaggctttg ccactagcca ttagcggcga aatatcacga
    43621 aaggtaatcc cctcctttgg gtaattctca attgaagcaa tatattgtgt taaatccatc
    43681 gtaaaatagt ctttctaatg tcttttaaat taaaatcttt cctattatag catgaaagtc
    43741 taaaaaggta aatgattcct aatcatccag atcaatccct ttttccttta aattagtcag
    43801 gcattcctgt aaataggcct cttgatgctc aggataaatc ggtgaggtca gtgccacctc
    43861 ctctaaatcc tcataggcgg caaggctttt tcctcggtaa tttttatcct gccagctcac
    43921 atctggctgg tagcctcgcg cctgcatttc ctgcataatc aacaggtgat actggtaaag
    43981 cttataagga gaatgggcaa acacatagtc aaccgtcgca tgtggtctcc cccagcctgc
    44041 tcctcgcaag gccgcacatt cacgatgctg ccccaacaat tgctgccttg gtaggcgtgt
    44101 gattaaatcc tgatgccaaa gacgcataag ctctcctatt tctcttcact agtcattaaa
    44161 tactgataaa tctcctgcgg actgcccaag gccataagct cttgaaactt taccagctct
    44221 tttagctgtt ggtaaatgac actgtcagcg atgctacgtt ttggggcatc agtctttacc
    44281 ctcatcagcc catcttcgat tactacaaag cctaactcct caaaaatttg tatcattttg
    44341 accaggagga ttttttcaat cttgaggtaa tcacttagca gggtcagctt atggcgcagg
    44401 tcaaattctg ggtattgata gatggtctta tagagcttgg caaattgctc tcgactgcca
    44461 tagcctgtta agtaataagg gtgcttaata tgatttttaa aatagatcgc ttcaaattcc
    44521 cgatgtctaa aaagggcttt caaagcttca atatcatcag gaacttcatc tatcacaaca
    44581 gccttagcct gctggtcctc aacagctgta ggaatatgct caggtgccct agcagtcctt
    44641 gctcgaatat caaacagctg caccccagtc actctagcgt caaccagcat taattgcagg
    44701 ctagtatgac ctcgccagtg attgatcgca agactaaccg ctaattccaa gccctgtgat
    44761 tgctggtact cctgtatcag atgtccctga ccaaaggcca agacatcagc ctcagcagct
    44821 cctttactga ccttgaattt caagtgactt tgctgctgac caatggtcct tgcctgctta
    44881 atggtaaaat cctttaagta aaaaacaggc tttttattat ccatgccaaa gggtgctaga
    44941 agcagcagct tgttcagact atctatactc aatgcttcta aatccaattc accgttgatc
    45001 aataaagtgt ttttcttttg accatcgtgt cctctgtctg tcacatactg gcaaagcagc
    45061 tctgatagct cctctaagcg atcagatgac agagtcatgc ctgctgcccc ctcatgacca
    45121 ccaaaggctg taaataagct cctattgcta ttaagtgctt caaagatatt aatgctctct
    45181 aagcttctgg ctgatccctt tgctagcccc tcatcaatag tcaaaacaag aacagtctgc
    45241 ccaatctcct ccatgatccg accagctaca atccccaaaa ctcctgggtg ccagccagac
    45301 ttagctaaaa cctgcacagg cttttctaga tcaaccatag ccattgcttg agcaaaaatc
    45361 tcttgtacca aggcctttct ttcctcattt ttaccactaa tcatcagggc aagttcatga
    45421 agctcttcgt catcaaagcc tgtcaataga tcaatagccg gatttggatc atcgagacgc
    45481 cctagagcat tgagctgtgg ggcaagctta aagccaataa catcttcatc aaagtgcgct
    45541 aagtcaacct ctgaaagctt catcagctcc tgcaagccta atctttctgt ctcttttaga
    45601 acagctagcc cgtttttgac aaggatacgg ttttcacccc gtaggctgac catgtcagca
    45661 attgtcccaa tagcaaccaa atctaaaaag tctactggaa ccgtctctag cagagcagaa
    45721 gccaatttga aggcaacgcc acagccggct agcttttgaa agggataagc agcagtcggg
    45781 tgctcagggt gaataatggc aaaagcctta ggcagctctg ctggcaagct gtggtgatct
    45841 gttacaataa catctacccc ctgtgcttgc gcaaaggcaa ttgcttcatg acccgaaaca
    45901 ccattatcaa cagtaataat cagcgaaacc tgctcttgct cgatgaaata cttgtaaaca
    45961 ctttgattgg gaccatagcc atctgtaaag cgattaggca aataaacaag aggctctgct
    46021 cccatcattt ccagcgtttc cttgacaatg gacgctgctg tcatgccatc tgcatcataa
    46081 tctccgtaga tcaagatcct ctcaaaccct tcaatggcct gacgaatgcg atgaacagcc
    46141 ttttgcatat catttagcaa ataaggatca tggagctgtg ataggtccgc tgtcaaaaag
    46201 ctggtaagct cctcttcggt atgaacccct cggtcataga tgagctttgc ggctgtctga
    46261 ctaagtccct ttgcctgagc cagcttaaag aagccagcgt ttggctcctt atcagctatg
    46321 gtccactgat acttggacgt aatcatttat aattaaatac ctttcttgca agataatcag
    46381 atatagttgg aaacaaggta taacacttat gagcaagggc taggctaata ggcagattaa
    46441 tctctcgttt cttttttcct attgcagcaa tgattttttt agccacagta tctgcctgca
    46501 gcgtaaagct agcaacactg gctaaatact gcccgcttgg gtcagcctgc tcaaaaaagg
    46561 cggttgcaat cgggcctgga ttaacagtcg tcacataaac ccgcctttct gccaactcca
    46621 agcgaagggc attggaaaag ccaatgactg caaactttgt cgcagaatag atacttgact
    46681 tggcagaagc tattaagcct gccattgaga caatattcat aatatgtcca gagccctgct
    46741 ctgccatttt gtggccaagc aagcgtgcaa aatgaatgct ggctaagcta ttcacacgaa
    46801 atatagcctc aatctcctct gctgagaaat catcaaaagc cttaaaagca ccaaagcctg
    46861 cattgttaat caaaacatca atcctgccat ggcgctggta aagctcatca acaagagcct
    46921 caatagcagc agggtcttga atagcaatct cgtagcactc cttgctagag atagcctgat
    46981 acagacgttc tagcctgtct ttgctgcgtc ctaataaaat caggtaatcc tcccttggaa
    47041 gctgtctgat gatggcctgt gcgagcccgc cagaagcacc cgttatcaga ataattctct
    47101 gtgccattag atgatcactt cctctaaatc gcgaacaacc tttacatttt caaaaatggt
    47161 tgccgcgtcc ttttccattt gacgacagtc acgtcctaaa aagcgtgctg aaacatgatt
    47221 cagcaaaagc cgcttagcac ctgcatcacg cgcgatttga gcagcctgca tgtttgtcga
    47281 atgcccatga ttacgggcca ttctttcatc acccttcccg taggtggact catgcaccag
    47341 cacatcagca tcttttgcca atctaacact agcagatgtc ttgcgtgtat cgccaataat
    47401 ggtgatgatc tttccttttt taggctctga aataaagtcc ttggcaaaaa ttctggtgcc
    47461 gtcttctagc tcaatatcct ggccattttt aaccttgcca aaaagtggac caaagggcac
    47521 tcctgctgct ctaagagctt ctgcatcaag tgttccttct aaatcctttt gaaccacacg
    47581 ataccccata caaaagatgg tatgtgccaa tcgctcagca taaacaataa atttatctgt
    47641 ttctaaaatc ttgcccatag aggtgtcatc aaactcatga taatgaatct gataaggcaa
    47701 tttagagcct gatatcctga tgctgtttgt tacataggat tttatcccaa caggtccata
    47761 aatctcaagg tccgtctgct cctcactagc ttgaaaagcc cgactagata aaaagccagg
    47821 caagccaaaa atatgatcac catgcagatg cgtgataaaa atcttcttga tttttcgtgg
    47881 cttgattgtt gtttctaaaa tttgccgctg ggttccctcg ccacaatcaa acatccacac
    47941 ctcattgatt tcatctaata gctttaacac taagcttgaa acgttgcgat gcttggctgg
    48001 ctgcccagct ccagtaccta aaaattgtaa ttccatacag tctattcttt ctaatgcaca
    48061 aggtaaatca tgaattctct ttgtgcaaac tgataatatt tctttccttt gaatgcttgg
    48121 ctaagagcca acaattcatc actattaaag ccctttagca gggtcacttc atttggtaaa
    48181 cgatagatcg tggttaacaa ggcatgctca ggtgttatgt cttctagctc tccttgctca
    48241 aactggcagc tcttcatctt gatcctacca tcttccacat aaaccacgta ttgtggaaaa
    48301 atctgagcca gctccagcag cagcgattcc tcaggctgcc cctgctcttt ttcagcaaaa
    48361 acaatcgcct cctgtgcttc attttcaaag acaaagccat aggattgccc caacaaattt
    48421 aagcggacaa agggcttcac ctcatcaaat gacggctctg aagtaaacag cttcaaggcc
    48481 cttgatagct caaaataata atctgtcgct gcttttggtg attgcttctg atatatttct
    48541 gcaaaataag cattaatcac actcggaggt ggcgtgatgg tagctaattt ttgctggtct
    48601 gtcaagccct ttaagcaatt ttgcaaataa accgtatcta aactcgtaaa gcctccataa
    48661 gtctttgcca attgaatata gtcagtcata aaattcttct aatctccatt tatttttggg
    48721 agcaatgtag ccagaaatct cttcaatctc cttatcaaag ctataaggct ccaataacgc
    48781 caacctgttg aggtcatagc atttgtaggc ttgatcctga cagagcttga tcgaaaatgg
    48841 ctcaaacatg tcccgaatct gatcaataag cagctgtctt aagaggctac gactgttttt
    48901 atcacgtgct gacagcctga catttggaaa aacagttgca gtcaagctag ctgtcttatc
    48961 catcttgtta taaatagcca gccttggaat atccagcata tctaaatctt tcaagatgtc
    49021 tagaacaacc ctctcatgct ccaaatgatt agggtcactg gcatcaatca catgcaagag
    49081 caaatcaaca tgccgacttt cctctaatgt cgacttaaaa gcagccacga gctccgttgg
    49141 taaatcttgg ataaagccta cagtatctgt cagagttgcc tgaaactgat tttgcagata
    49201 aatttgcttg gtggtggcat caagtgttgc aaataattca tcagcctcat attgcttgtc
    49261 accagtcaaa atagtcataa tagtagactt acctgcattg gtatagccga tcaatccaat
    49321 attaaagaca tcagaggtca tgcggcgatc acgaatcgtt tgacggtttt tttcgacagc
    49381 agctagctgc cgctcaatat ctgcaatctg atgacgaatg gagcgccggt tcagctccag
    49441 ctggctctca cccggcccac gactcccaat gcccccggcc tgacgactaa gcataactcc
    49501 ctggccaacc agccttggca gcatgtattt gagctgcgcc aaatgcacct gcaattttcc
    49561 ttcatggctt ctcgctcgca tcgcaaaaat atcaagaatc agctgcatgc ggtcaatgac
    49621 cttaataccc aaggcagcct ccaaattggc attttgccga gccgttaagc gattgttcac
    49681 aatcactgta tcaatctcat tggcagcaac catttcttta atttcggcta gcttgccaga
    49741 gccaacgaag gtcttgctat catagcgctc ccgcctttgc atatagcaat caacaacctc
    49801 tgcacctgcg gtcttggcta gactagccag ctctgtcatt gatagctcag catggtcagc
    49861 tgcctctagg accacaccta gtaaaatgac tctttcctgc cttgcctttg tctctatcat
    49921 gaacgcgact aatcctccaa attccgtagt gtttattata gcatagtttt agctattttc
    49981 agctagtttg ccatcgatag ctctaaggct ccttcaaaaa gcgctccacc ctatcatata
    50041 ttgcctgcgg ataggacgac tcgctaatcg agtcaaatcg cactgccata cggttacgaa
    50101 accaagtcag ctgtcgttta gcaaagcggc gtgtttgctg ctttagtgtg gctgttgctt
    50161 cttctagact agcctgaccc tgaaagtaag gaaagagctc cttatagccg atccctcgac
    50221 tagcctgaac agctggatac tgctcaaaaa gccaccttgc ctcctccaat agacctgaag
    50281 ccatcatcag atccacccgc ttattaattc gctcataaat aacctcgcgc tcatcagtca
    50341 atccaatcat caaggggtta tagggagcct cctgattttt taaatcccta gcaaattgat
    50401 ttagctcaag tgagcgaatg gcacgcctgc ggttaacctg atcaaggtga atgcccttac
    50461 tagctaatag ctgataaagc tctgtatctg tcagtgtctc tagctgctgc cgataagcaa
    50521 gcagctcctt ttgatcaagg tctcctccta aatgatagcc ctctaacagg ctttgcaggt
    50581 acaagcccgt accaccgaca ataatcggca gcttaccgcg gctaacaata tcttcaatag
    50641 ctcgcttagc gtcctgcacg aaatcaaagg ctgagtaaga ctctgtcacc tcacgaatgt
    50701 caatcaaatg atgaaccgca agagcctgct ccctggcact agccttagct gtcccaatat
    50761 caaggtgacg ataaacctgc tgactatctc cagatataat ttcaccatta aaggcaccag
    50821 ccaaggcaat ccctagagct gtcttgccaa cagcagtcgg gcctacaatc acaattatct
    50881 tttcttttgt catttattgt ctttctactt aaaaagcagc tgaaaaagtc ttttacttga
    50941 attttctaat ctttttcgct accatatatt ataacataag attgagagac agttatggtc
    51001 ctcttaatag aaatggagaa tgattatggc taaaaaacat ggattcgcaa agggtcttgc
    51061 tacaggtgtt cttgctactg ctgctaccgt tgcaggtgca gtatttgctg ttaaaaagac
    51121 tattattgac cctgaggaag aaaaagcagc atttgtagag gaaaatcgta aaaaagcagc
    51181 acgtcgtcgt gttgctcgct aatcactaat agatgaaaga ttcgacaggc tttatcaata
    51241 gcctgtcgga ttttttattc cgtgagacta gacctttagc ttagtcacat atcaaaaata
    51301 gctcgtcaac gccacataca gcctactgcc ttgcccaaca aacagatcaa actaaggcta
    51361 attttcactt atatggcacg tttcgactgt aaaacgattt tgcgattgat tgaccacaat
    51421 atcaaactgc ttttgataag gctctaggta acgaacatac tgagttcgcc gatgagcatg
    51481 gctctgctga atgaactccg gattgcggcc tcttgatcta gtatctctat caagccgcct
    51541 ttggagctct gtgtcatcat ctgtataaaa gtaaagtgat aagtcaaaca gctctggctc
    51601 taaaaaggtt gttgacatgc cctcgacaat aaggatcggc acatcaccct taaccagacg
    51661 agagggcgcc caaggggtat caatactcaa aaaatccaat ccttgcttaa acatcatgat
    51721 gtcacgcctc agactggcca attcatgcct agcagggtga caggctgtta tactatgaag
    51781 cacctctttt ccctgataag ggtagctaat caaaacagcc tgactaaaat cattagcgat
    51841 gatataggca tctgtttcta acaattggct ttgtccatca ggcaaaagct gctgtaagcg
    51901 cttagcaaag gttgatttac cagatgcacc atgaccacta attctaataa gcattttctc
    51961 acgattggct gctgcagtta caatagcttg aagtagcttc tccattatct ctcctcatca
    52021 aataatattc taataatagg acatcattct accaaaaata gcatcgaaaa acaagccggt
    52081 ctcctgaaac agcctgactg gtagcaaaaa aaagattgaa gggcaatcca acaaggaaag
    52141 ctcctccaat ctgattaata gtctataatg acttaatatg agtgccaaat gtcttggtta
    52201 tattgttcaa tcgtacggtc tgatgagaag aaaccagcct tagcaatatt atgcacaacc
    52261 tttgtcagcc ataggtcctg attgtcataa tcagccagca tttgttcttt gactgcaatg
    52321 tattcctcaa ggtcaattaa ggtcataaac cagtccttag agattaactc cttatagaga
    52381 cggtcaagac gttcctcatt accaagctct aataattctg gactgataat aaagttaact
    52441 gcttccttga tagctgggtg ggcatcataa tagtctttag acacataacc acctgtggca
    52501 taaagatcaa taatggtatc tgaatcctta ccaaaggtgt agatattatc cataccagca
    52561 agctcagcga tttccacatt agccccgtcc atagtaccaa gcgtcaaggc accattgagc
    52621 atgaatttca tattaccagt acctgaagct tcctttgaag ctagagaaat ttgctctgaa
    52681 atatcagttg caggaatcaa atgctctgct actgtcacat tgtagttttc aacaaggtga
    52741 acattaaggt atggacttac ctccggatcg ttattgataa gctctgacaa gcaaagaatc
    52801 aaatgaataa tatcctgtgc aatgatataa gccggtgcag ccttaccacc aaagataact
    52861 gttattttac gcttcggcag gttgcctttt ttgatctcta agtatttatg aatcacataa
    52921 agggcattca tctgctggcg cttatattcg tggaagcgtt taatttgggt atcaataatt
    52981 gaatgctcat caagctcaat tcccttatta tccttgaggt agcgctttaa ggctacttta
    53041 ttatggtgct taatctcagc caatcttgca tgaacagctt gatcctcagc aaaggccatt
    53101 agtttttcaa gccttgtcgc atcagtcaag taagcatcac cgataagctc tttaatatag
    53161 tccgccaact cttggttggc gaattctagc caacgacgga aggtaatacc attggttttg
    53221 ttgttgaatt tttctggata cagctcatag aaggccttca attcactatt tttcaggatt
    53281 tcagtgtgaa gagcagcaac cccgttgaca cttgtggcaa aatgaatatc catatgtgcc
    53341 atatgcacac gacctgtctc atcaatgatc tgaacggcta gatctgatac ccttgcacga
    53401 acaagagcat ctagttgctc aataatcgtt accaaatgtg gcacaacctc attgaggaag
    53461 tcaagaggcc atttttccaa ggcttctgca aggatcgtgt gattggtgta gccaaccatc
    53521 ttttgcacca ctgaaacagc ctcatcaaaa tcaaagccat gcttttgtgt caatagacga
    53581 atcaattctg gaatgaccat tgatggatgg gtatcattga tttgcacata tgcgtaatca
    53641 gccaaatcat gcaggtttga gccacgctca atggcttcgt caatcaatag ctgagcggca
    53701 ttagatacca tgaaatattg ctggtaaatg cgaaggagct caccattttt atcagaatca
    53761 tcagggtaaa ggaacagggt caggtttttg gcaatgtcag tcttatcaaa tgaaatgcca
    53821 tccttaatca agccataatc aacaccttca atatcaaaaa gattaaggta atttttagtg
    53881 tcgcgcttgt agcctaaaac atcaatacgg tctaaacgag acttcagggt aaagttttta
    53941 aagggaacat catatgaaat atcagtcggt actagccaag agtcatcctc tatccaaaaa
    54001 ttaggctctg ctgtttgttc attgtgccta aagacctgct tgaacaaacc acaatggtaa
    54061 ttcaagccaa ccccttcacc attaatgcca aggcttgaga tagaatcaat aaagcacgat
    54121 gccaaacggc caagaccacc attaccaagc gatggctcca attcaacgtc ctctatctca
    54181 gcaattgatt tgccagcagc agccagctcc tctttgatgt ccttataaat acctagatta
    54241 atgagattat tagaaagcaa tttaccaatc aaaaattctg ctgagatgta ataaacctta
    54301 cgcttagctg tattttttgt ttttttgctt gcttcttctt tgacatagga aagcaatgaa
    54361 agatagattt cctcgttgct tgcacctgca agagattttc ctaatgtcat ttcagtataa
    54421 tctgtaaagc gtttcatgat atcctctttt caatatagta ttctagtgat gattattggc
    54481 tcgaccatat agctcagtca agtgtattaa gtaagtctta tgcttctctt taaggtcgtc
    54541 tttaagcatg cgccattgcc agttgccacc aacagtgttt ggcatattca tgcggctatc
    54601 agctgactta tccagcaaat cctgcataca caggatagca gtatcacaca cagtcgcaaa
    54661 gattgttctt agcatggcct tggtgatgct ttcatcagct gccttatgaa tgtaatgatt
    54721 aacaaactca acctgctctg cgctcaaatg ctcataccag ccattaacca cctcattgtc
    54781 atgcgtacca gtgtagacaa tgcaattgtg atcataatga tgcggcaaat caaagctttg
    54841 actcgtcaca tcaaacaagc caaactctaa aattttcatg cctggaaatc cagttgaggc
    54901 aagcagctgc tctgcctttt catcaatgta gccaagattt tctgcgataa ttggcaaatc
    54961 acccaaagcc tctctgacag ctgtgaacaa agcaattcca ggggctgact cccaatgacc
    55021 atttttagca gtcacatcac caccaggaat ttcccaaaaa tctgagaagc ccttgaaatg
    55081 gtcaattcta agcttatcgt atagcttgaa gctctctttg atccgatgaa tccaccatgc
    55141 aaagcctgtt tgctcatggc tctcccagtt gtaaatagga ttgccccaaa gctgcccgtc
    55201 ctcactaaag ccatcagcag gtacacctgc aatgtaaatc ggctttttat ctgcatccac
    55261 cttaaagagc tctggcatcg tccaaacctc aacactatca gcagaaacgt agattggcat
    55321 atcaccgatg atggcaatgc cattttgatt agcatagatc ttcagcgcta gccactgctg
    55381 ataaaagaaa tattggcaga ccttatgata ggtaatgcct ttggccaaca gcttgcggta
    55441 atgaagcaag gcagcctctt cacgcttaac aattgctcta tcgtcccatt cctggagggc
    55501 cttgtgatca aaatgctctt taatagccat aaattcagca aaatcattta gccagctcgc
    55561 agttgcttca aattcggcga gctgtcttaa gccttcctca gttgagacaa aagcctgaac
    55621 tgctttttct aataaagggc gtctggcttg aaagacttga gcgtaatcaa cagactccgg
    55681 atttgagcca aaatcaacag cagcataatc agcttcctgc aaataaccgt cctttgctag
    55741 caattcaagg tcaataaaat gcgtatttcc tgcaatagct gaaaaagatt gataaggaga
    55801 atctccaaag ctagttgttg ttaagggcaa aatctgccaa taggtctgct tggtttcctt
    55861 taaaaagtca acaaattcaa aggcctcttt accaaaactc ccaataccga agcgtcccgg
    55921 aagcgagctg atatgcatca gaataccact tgcacgttta gtcattcttt tttctccttg
    55981 taaaatcttt atgttgaaat tataacgcaa ccgtttgcgc aagtcaatat cttttcaaaa
    56041 aaaagagact ttttcggcat gctagagctg ctcaagcctt gataataatg aaggaagcag
    56101 ctaggacaaa aacaaaaaaa ggattggaga gacagcctaa gcagctgctc ttccatcctc
    56161 atctcactcc tatttggcat taatatccct gacactctcc cgctttttga ggctaaaggg
    56221 aaccaaaatt ttctgactca gggtttgttc attggcattg ataatgtcta agagctgcct
    56281 aaaggaggtt cttcccaaat tttcaacgtt aatatcaaat gttgttaaat aagggtgaat
    56341 caatttcgaa tagctagaat tattaaaggt aataatcgaa atatcatctg gcaccttaat
    56401 gtcataaaag gacaagagct ggaccattcg caccgacaaa acatcaccaa tcacgattaa
    56461 ggctgtggcc ttaaagctac gtattgtttc aataaccttt tcaatgctga ttggatcctt
    56521 tcgatcaaat aacagcatcg gtttgttttc caaagacaat ttcaagcagc ccttgagata
    56581 gcccatatag cgctcagaag ctacctctgc ttccaaatcg tctgtaataa acaatatctg
    56641 tctgtgaccc ttttgataga gatgatcaac tgcagtttta gccattagct ggttgtcatt
    56701 gtcaatatag gtgattttgt tctcatcacc ttctggtgcg ccaacaatga caaaaggaat
    56761 ctggttggtc atcaaatagc ctctaacagg gtcttcttgc tcagaataca atataataaa
    56821 gccatcaaca cgcttttgca ggtgcattaa cttaacctgg ctcaataaat cctcaacaga
    56881 catacctgtt gcaatggaaa cagtgaaatg atgtttctta gcttcattgg taatggtcga
    56941 tagaatttcc ataaaaaagg gatcactcaa acggtcattg gtgataatcg gcggaaaaac
    57001 cagaccgata ttatgtgtca gaccactagc aagcatttgc gcagctacat taggaacata
    57061 gccaagctcg ctcatagctc ttctgacctt ttcctttgtc ttttgagaga tggagcgatt
    57121 atcctttagc acacgactga cggtcgaagg attaacaccc gcttttaagg caacgtcttt
    57181 tattgtaacc atataaacct catttaatac ctgataatga cgctatgtca ggctttttca
    57241 catgtatttt gcttttatta tacaattatc tcctaaaaaa tcaactcttg ccctgcaaga
    57301 ggacagcata aaaaactgct gtcgtcatga tcgaaaaaat gttttaaaaa aatcaacttt
    57361 ttttaaaaaa agacttgact ttttctgcaa gcggttgcat aatattaagt gtaagaaata
    57421 tatcttagga ggaaatcgct atgaaatcat ggcaaaaagt tatcgtcagt ggggcaagct
    57481 tgacacttgc tagcgcctta ttagtagggt gtgcatctgg ttcaaaggac aaaacagaaa
    57541 ctgcatcagg tactgattca aaaacaatta agctttgggt accaacaggg gctaaaaagt
    57601 catacacaga tgttgttgct aaatttgaaa aggactctgg ctacaaggtt aaggtgatcg
    57661 agtcagagga tccaaaagca caagaaaaaa tcaaaaaaga tgcttctact gctgccgatg
    57721 tcttttcact tcctcatgac cagcttggtc agctcgtaga atctggtatt atccaagaag
    57781 ttccagagga atacactaaa gaaatcgctg acacagcaac tgatcaagct atccttggtg
    57841 ctcaatacaa gggtaaaacc tatgccttcc catttggtat tgagtcacag gttctcttct
    57901 acaacaaaac taagctagct gctgatgatg ttgcttcata cgatacaatc acgtctaagg
    57961 ctacctttgg tggtaccttc aagcaggcta atgcttatgc tactggtcca ttgttcatgt
    58021 ctgttggtaa cacgttgttt ggtgaaagcg gtgaagacgc taaaggaact aactggggca
    58081 acgaaaaagg tgttgctgtt cttaaatgga tttcagacca agcctcaaac aaaggatttg
    58141 ttaacttaga tgccaacaac gtcatgtctc agtttggcga cggttcagtt gcttcatttg
    58201 aatcaggtcc ttgggactac gaggcagcac aaaaggctat cggtaaagaa aatcttggtg
    58261 ttgctgttta tccaaaggta actattggtg gtgaaaccgt tcaacaaaag gccttcttag
    58321 gagtgaagct ctacgcggtt aaccaagctc ctgctaaggg agatactaag cgtatcgcag
    58381 ccagctacaa gcttgcttca tacctaacaa atgctgaaag ccaagaaaac caattcaaga
    58441 cacgtaacat cgtaccagct aacaagaccg ttcaagcttc agaggctgtt caatcaaacg
    58501 agcttgcaaa aacagttatc acaatgggat cttcttcaga ttatactgtt gttatgccta
    58561 agcttagtca aatgggtacc ttctggactg aaagtgctgc aatccttagc gatgccttca
    58621 atggtaaaat caaagaaggt gactaccttg ctaagctaca gcagtttgac aaggacattg
    58681 cagcaacaaa ataagctatc tcatttataa tactatccta aacaagtaca gaggtgggct
    58741 attttaacgc tatcctttct actcatctct aaaggggtgg agctaagcat cattattttt
    58801 tcagggctta gtccactcct acttgttttt gatatgacgt aaagcttggt gctacttaaa
    58861 tttttaattg cttaaaggtt taggtaacac ttagctatgt ggtcgttagc accaaacgct
    58921 tatgaccaca gcatctgaac aagagagtca ggtaatccta ctttcttgta tcctaacata
    58981 aaggagaaca tatatgactc aggcaggctt agcatctcag gttactgtaa aagaggcttt
    59041 aacaaaggga agcttcgata taaaactatc cgctatcatt atgggctttg ccaattttgc
    59101 taataaacaa ttcgtcaaag gaacactctt tttattgagt gaggtggtct ttttcatcgc
    59161 ctttgtttca caaatcattc ctgctattgg cggcctcatt accctaggaa cacaaacaca
    59221 gggcatgaca accaaaacta tcgacggtat cagcattcag gttgctgttg atggagacaa
    59281 ttcgatgcta atgctgattt ttggcttagc ctctctgatt ttttgtttgt tatttgccta
    59341 tatttattgg tgtaacctaa aaagcgcccg tcacctctac atgctaaagc aagaaggggc
    59401 aaaaatccca agctttaagg aggattttgt tagtctagca aatggtcgtt tccatatgac
    59461 cttgatgaca attccattga ttggtgtgct tctgtttacg gtacttcctt tgatctacat
    59521 gatttgctta gcatttacta actttgatca caatcacctc ccgccaaagt cactttttga
    59581 ttgggttggt ctttccaatt ttggtaacgt gttaagtggt cgtatggcag gaaccttctt
    59641 tcctgttttc tcatggacac tgatttgggc tgtctttgcc acagtgacta acttcttctt
    59701 tggtatcatt ttagcactct tgattaatac caaaggctta aaattgaaaa aaatgtggcg
    59761 gaccttcttt gtgattacca tcgcagttcc tcagtttatt tcactgctga ttatgcgaaa
    59821 tctgctaaat gaccaaggtc ccttaaatgc cctgcttagc aaattagggt taatccgcca
    59881 ttctctaccg tttttatctg atccaatttg ggctaaattc tctattatct ttgttaatat
    59941 gtggattggt attccattta ccatgttaat cgcaacaggt atcattatga atctgccaag
    60001 cgaacaaatt gaggctgcag agattgatgg ggcaagtaaa tttcaggtct tcaaatcaat
    60061 caccttccct caaatcctca ttatcatgac accaaacctg attcaacaat ttattggaaa
    60121 catcaataac ttcaatgtga tctatctctt aactggtggt gggccaacca attcagccta
    60181 ttaccaagct ggaaccaccg atctattggt gacttggctc tataaattga ctgttacagc
    60241 agcagattat aacctagcct ctgttattgg tatcttaatc tttaccgtat cagcaatctt
    60301 tagcttactg gcttacacaa gaactgcatc atacaaggaa ggagcagcga aataatgaaa
    60361 aacaaacgtc gatttcagct tggattagtt tacgccattt taaccgttct ctcaatcatt
    60421 tggcttttac cgatcgcttg ggttgttctg actagctttc gtgctgaagg cactgcttat
    60481 gtcgattatt ttcttcccaa gcacctcaca ttagaccatt atattaagct ctttacaaat
    60541 gaaacctttc cttttgggag atggtttgtc aatacctttg ttgttgctat ctttacctgt
    60601 atcatctcaa cctttattac agtggcgatg gcttactcgc ttagtcggat caaattcaag
    60661 tttcgcaatc gtttcttaaa gcttgcacta gtgctaaaca tgtttccagg ctttatgagc
    60721 atgattgcta tctactatat cctaaaagca cttggcctta cgcaaagtct taccgcccta
    60781 gtccttgttt attctgccgg tgctgcactt ggattttaca ttgctaaggg cttctttgat
    60841 accattcctt attcgcttga cgaatctgcc atgattgatg gggctactcg tatggatatt
    60901 ttctttaaga ttaccctacc gctatcaaag ccaatcattg tttacactgc actccttgcc
    60961 tttatgggac cttgggttga ctttatcttt gcccaagtga ttttaggaga tgcaaccagc
    61021 aaatatacgg tagctatcgg actcttttca atgctgcagc ctgacaccat caatgactgg
    61081 ttcatggcct ttaccgctgg atctgtgtta attgctattc caatcacatt gctctttatg
    61141 tttatgcaaa aatactatgt agagggcgtt acaggtggtt ctgtcaaata gcagtaatga
    61201 tcacgataac ccttactcaa aaaatccttc ccgcttggga gggatttttt gatgtcagca
    61261 agggctaagc tagtgcttac tcctcatctc taaactgagt tttgtaaaag actagaacca
    61321 gcatgagcag tgtgccaaag acctgactat tcatgataac aataggattg tgcacccaaa
    61381 agcttataag cactgctaaa agcgtaggaa gtccaaagca attcactagc aaacccaagc
    61441 attctgagta gctcttgagt gaaaataatc tagcagatct tgttaataac agtgataacg
    61501 agccaattcc gatcactaaa ccggctccta gatagaccac actgctagcc actagcagca
    61561 aaaaggcaag cacagcggca cgattgctat tgtaccattg ctgattaaca aaggccttga
    61621 cagcctctag agaggttaag cgcgttagcc tttccttgtt gcctttaacc ttagcagtta
    61681 gcctttgacc atcaggaaag cttaaaatcc atgaggtttc tgttaatatc agctggcttc
    61741 tttgatcttt ctttagctct tctactattt ctggtgttgg caatacagca acaacagcat
    61801 cagtatcctc tataaggact gtttttccat catagcgatc atgccaaata gtgccttgtg
    61861 tcaaggcgtg ataggttttt tctgtcaagg agcctaaacc attacggact atttgctcta
    61921 agggatagct cttcaagctt gcataatgca gcgtgatagg cattaacacc agagcattga
    61981 gaaagagcac taaaatcaca ttctgccacc acaaaaaggc actgcgatga gcaaatatca
    62041 ttttaggaga aaagataata gttgtgtaag aaataggaaa tcgatcattc gtcatgataa
    62101 aagccccttg agagataaat taaccctttg ttccaccatt agttaagcct gaaacaaaat
    62161 gcttttgtaa aaagaagaat agcactgaaa ttggcactgc gattaaaata gcccctgctg
    62221 caaacaacgt gaccttagga tttctagcgt cattagtgat gaatgactga agacctaccg
    62281 ctacggtgta acgctcctgc tcacgtaaga gaaatttcgc aagcataaag tcaccaaagg
    62341 gccccataaa ggcccacagg gcctgaacag caaccatcgg acgaaccaag ggaaatacaa
    62401 tttggtagaa ggtcctaaaa tgaccagagc catctagctt agctgactca tctaaatcat
    62461 aaggcacagt atcaaaatac cccttcatca accaagcatt catcggaatg cctcctccaa
    62521 cataaatcag aatgaggaac caatagtgat tcagagcatt aaacaaccaa gccatcacaa
    62581 aataagctgt taaggcagcc attgtcggaa ccatctgaac cactaagaaa aagaccaagc
    62641 tcttttgacg cccaaaaaag tgataacggc tgtaagcata gcctgtcagc gtaatgactg
    62701 tcacctggat cagcatcgtg aaaaaggcga caactaacgt gttccagtac catcttaagt
    62761 aataggtgtc ctgaaagagt gtctcaaagt ttgataaggt ccaaggccca tcaatatgaa
    62821 agctaaaggc agttgtattt cctggcctaa aggctgagct aacggtcacc aagattggaa
    62881 ataagatgat gatcgacagg attagcaaat agctgtaagt caacagctga gctaacaagc
    62941 gcttcttctt cactgactgt ggcaaataat tcctacccat ttagcgatcc tccatgtcaa
    63001 aggctttgaa ttttttaaag gttatcaatg atacagaaat aacaatcaag gaaatgatta
    63061 aggtcaccgc tgaagcaata gaaaactgtg gtgacgtttg tgtggtcagc ttgtaaatcc
    63121 aagaaatcaa aatatcggtc gatcctgcac cgccaccaac tgtaccagga cctccattat
    63181 taaagaggta aataatagag aagttgttaa aattaaaggt atactgcgaa atcaaggttg
    63241 gcgctgccac agcaaagatc attggcaggg taatttggcg aaacttctgc agggctgttg
    63301 ccccgtcaac tgttgctgcc tcgtataaat cagcaggaat tgactgtaaa ataccagaca
    63361 ccaaaatata aatataagga aagcccagcc agccctgaac cataatcacc gcaacctttg
    63421 tccaaaaagg atctgtcttc catgggataa tcccaaactc tgcaaatggc acaaaccttt
    63481 ctaaaaatgg taacacctga acattcatag cgccaataga atcattaaag aaattaccaa
    63541 agctcataat cgagataaag gcaggcactg cccaaggcaa caagaaaatc accccaaaaa
    63601 ggcgcctgca cttcacgaag gactgattgg caataatagc agtcgctatt cctatcacaa
    63661 tctggagact cgttgccgcc agggtccaaa tcaaggtcca tgacagcaca gagccaaagg
    63721 ctgacttaaa ggtgctaagc tctaaaatgc tcttgaaatt ctttatgcca acccaatcta
    63781 atagcttata aggaggaata tgcctaaaat cataattcgt aaatgcaatt aatagggtaa
    63841 caagcaccgg aaaaataatg gcaaaggcca tggccaagta agctggaata atcagcaaat
    63901 aaggaaagcc cttttcatag atggattgta ccatttcttt taaggttaat gaaatgctat
    63961 gacctgcatt gatctccctt gccactagcc tagcgtctcg catggcagcc aaatgaaaga
    64021 tcaaaaacaa ggcaaatagg ataagctgca tagctccctt aatcaataag aatagggaat
    64081 gatcctccat tggcacgcta ccaagactgt acaagccagc aagagccgga ataccaacaa
    64141 agaaagcctc tagcagctca cctaaaaaca caagaagcaa aataaagcct tttacctttt
    64201 gagtattata gaattgccct agaccaggga ttattgaaag ccacatggct ttttgtggat
    64261 tcttcatttt ttcattttta agcatttgtc attcctctct atcacccttt tatggttctc
    64321 ctccttcata gagtattaaa taacatcaca gataacgcaa ctattttttc aatgaaatgg
    64381 tttgagcctt gctatcagtt ttaatggtat aggtttctgg gctagtccac aacacattac
    64441 cagagctatc cttctttaca agatgacagt taatggtttt gttaataggg agattgacat
    64501 cataaaacca atttgggtat ttggcaattg actgtgttgc attaaaaata ggccctaaag
    64561 ctttatgatt atcatttgcc ccaagctcaa ccacatcacc aacgatataa agctgttctc
    64621 ctaataccgt attgaaatca ttaacaacta atcttactgg aatttgctta tctgttaaca
    64681 cttcaaaggc cttgtaaaca ttactttcct gccctgtaga tgtggtcacc ttaatgtcat
    64741 ggtatccagc agctacagcc ggtatcttaa attgaatcaa ggtatcgtcc catgacacaa
    64801 tatctgcttt gctatcacca aaatgaagct gaccttgagc actaccaaat ccttgccctg
    64861 aaatagaaac tgtatttcct gcgacgccaa acgaagcgtc tacgtctcct atctgtggtg
    64921 tctcattttt ccctttaaag gtccaaactg caacttgacc tgcacccaat tcaaacgcct
    64981 caacattacc atcagctgat accgttaatt cctttccacc aagtaagcca cctaattcat
    65041 cagcgtactt accagctggt aaagccgttt tagcgccact aatggtgtag ccatttgtct
    65101 gatccttatt gacagccact aaagcaacgt catttccaaa ttttctttca aagaccaaga
    65161 cctgatcatt aatccagcgc tgctgtgttg ttccataagc caaggcttga tttttcttac
    65221 gcagcggtgc taatttacta ataacctgat aagcagtgga attcttatca aatgttggca
    65281 tatcaccacg attttcaggg tcgttagcac ctgtagcata ctgctctgaa ccataataaa
    65341 gattcggaac accacgcgat gttagcagta aagcataggc ttgattaaca gctgtctgat
    65401 tatgattgac tagagtagca aagcgggtca tatcatggtt atcaatgaaa gtcacttgat
    65461 ctgaaacttc cttatactct ttttccgtag ctacaatcat attgtaaaaa tcttgcattt
    65521 tcgctgataa atcagaatac aggcgcctaa cagaattagc aaacctaaaa tcaagcaggc
    65581 tcatgccgct agtatcagca aatttagtca tcaatggatc attaaaagaa ccgtcagcaa
    65641 accattcccc aaaggcgaat acattatgct tctcatagat atgactcaac caattttttt
    65701 gccagccttg tgacatatgc ttgaccgcat ctacacgaat accatcaatg cccatttcta
    65761 accatttatc aatagcctct ttgagataat cgtcaactgt tggattcaga ttgttcaagt
    65821 ctgccaagcc atacatggaa tgataaatgc tattttcata agttgaaaaa tcagtccatg
    65881 actcatgatt aaaaatcttt tgatcatcat gactgaattt accaacaagc tgaccgtcct
    65941 tatacaaagc accatcttca gggaaggtta gtcctttata ttctgctgtt gaggtatgat
    66001 taggagcaaa atcaataact actttaatgt ttttgctatg tgccacctga atgagctttt
    66061 taaaatcctc cattgttcca aagtgactgt ttgctttgaa aaaatccttt gcccagtagc
    66121 catgataggc tgcactgcca tttgaagggt caatggtatc aatgttttca actggtgatg
    66181 aaatccagat agctgatact cctaaattgg ttaagtagcc atcttctagt ttcttaatga
    66241 tacctgccca atcaccccca tgatactttt tgggatcatt tttatcaaat acatctgtat
    66301 ttccattatt agcagcatta ccatcatgaa aacgatcggt gacaatttga taaatcgtgt
    66361 cagtagaaaa atcagcctta ttagacactg cagtattttc aatagcaaag acactgttag
    66421 ttgacattgc taaggtaacc gctgccatag ctactgttaa tgctttacga catgttaaag
    66481 taatacgctt catccttaac ctcctttgat aaaacgccat attaatagct aacaacaaac
    66541 ccgttctgga gtagctcaaa tgtctcttta tctacaccat tagaaacaag cacagaacct
    66601 cctttctcaa taggatatgg cttgacgcca ttattaacca gcaatcttat tgattgaccg
    66661 tttaattcac gctttacgca aaggcagtca tcatgggagg ttatcgaaat gcttccagat
    66721 tggataaccg catgacgacg caggctgata atgtccttaa cctgattcca aaagctcata
    66781 tcccaagtgc tgctgtccca attaaagcta cgtctagagt caggatcata acctccctcc
    66841 atcgcaagct ctgttccata gtaaatacat ggtatgccca taaaggtaac taaaagggct
    66901 aagccagcca ataatttgtc cttagagcca ttcacctgag tcaagaagcg atgcgtatca
    66961 tgggaatcca gtaaattcag attcatctgg ttgacctgcc aagtatttct cattaaaata
    67021 tgcgacaatc tttcagccat ttcctgtgaa ctaatcgcat caaatgcaaa ataatcgaga
    67081 caagccttgg taaaggcgta attcatgata ccatcatact ggtctccttg aaggtaggga
    67141 taagcatcat gccaattctc tccaataagt atcgcatctg atttaactgc cttaacagcc
    67201 tttcgaaagc gtctccaaaa atcatgcgat acctcatcag aaacatctag tcgccagcca
    67261 tcaatatcgt attctgtgat ccaataaaga ccaatagcaa tcaagtaatc ctgaacagcc
    67321 cgatgcgagg tattccactt aggcatgtag tgacaatcag cgaaggtttc gtaattagct
    67381 agctctacag aaggatgatc tccttgaatc ataaaccaat caaaaaatga agaagcacta
    67441 ccatgtgcca aaacgtcctg aaatggctcg caatcactgc tagcatgatt gaaaacagca
    67501 tctaaaataa ttctaatccc tctttggtgg gcctcgttta ttagttgctg gagatcaagc
    67561 gatgtcccaa acatcgggtc aatagcatag tagtcactaa tatcatattt gtgattactg
    67621 atggatttga aaatcggtgt caagtaaatg acattaatac caagatcttc aaggtattcc
    67681 agcttatctg taatcccctt caaatcccct ccggcaaagc tattaggagt tggcctatcc
    67741 agccaagcca tattaatata gctatcgtcc ttttcaaagt caccacgatg aaagcgatca
    67801 acaaagatct gataaaaaac agcatcatgc acccaaggga cagtctgatg aacgtctaca
    67861 gcattaatat aaggcatttg aaaaaagttg taaaagccat ttgaaaaatc atagcttgtg
    67921 gtcaagccat cctcactaaa gtaataggta tgaccagatt gctcaagctt aaaaatatag
    67981 gccaatctaa catcatcaag gcttaaggtg atttcataat aggtatgggt atgatcggta
    68041 taagcagcat acatcgccag ttctttttga tactcatgat aatgatactt aggtccataa
    68101 accagcgtca ccgctatatc gttatcctcc tttgcaaccc tcaaccgaat cacaagctcc
    68161 tttgttgata aggcaaagca atatctagaa tctggaatat gcagtattcc ggctgtgttc
    68221 attttttcct ccctaggttc atcagtctta tcagatactc ttattaggac aagatgggaa
    68281 acaagacaag ctagtcacta ctacttttta ttattatctc ctcatcgccc actctgatac
    68341 tataggtaac aagatggaga ctaggatacc tttatcccag cctccctttt tatgttattc
    68401 agtgtatttt tgtgcaatag cctcttgaat ggttttagct gcttccttag cagccttggc
    68461 aggagtcttc ttgcctgctg ctacctcaaa gaacatgttc gcacctggtc cccaaacttc
    68521 tgccatttct ggaatatttg gcattggctg agcatttgag aattgcccga taaccgcctt
    68581 tgtcaattca tttccttgtt ctgcagcata gctgcgagca gctagattgg cagggatctc
    68641 ttgtgtctta tcataaaagg ctttttggtt tttctcattt gtcacatagt caaggaattg
    68701 ctgtgccagc tttttattct tagaataatt tgaaatcacc catgctttac caccaccaaa
    68761 ggcttgatag ctaccgccat taggtaggct tggaatttgt gccactccaa agtttacacc
    68821 agcctcctta aatgaggctg cagcccaagg tccatcaata atcacaccag cctttttaga
    68881 ggtgaattgc tctgtaataa aatctccagc cttttgggta tcctgcatgc cttgaggcca
    68941 tacactatac cacttcttcg catactctaa gccttcaata gtaccagcat taccaatacc
    69001 caagtccttt ggatcagtcc ccttatctcc aaatacataa gccccatagc ctgcaatcaa
    69061 gccatagcca taatagaagt ctgtccactt agcaagaaag cctacagact tgccgtcttc
    69121 agaggcaaag gcaaacttag gatccttatt tagctcttca atgtcagcaa aggttttcgg
    69181 agcctctgat accaaatcct tgttataata catcaccaag gtttcaataa catttggtgc
    69241 cccataaacc tttccattta tggtaactaa ctttttaaca gtatcatcaa actggtcagc
    69301 attgcctaag ctcacttcag caatttgtcc ttcagagcca agtccaccaa cccggtcata
    69361 tggtgctaaa aagacgtctg gcgaagcacc tgtcggtcca tcagtagaca gcttatctag
    69421 cgtgtcaatc atgccttcct ttttgacttt gaccttaacc ttattgtcct tttcaaaggc
    69481 tgtcttaatc tctttgatgt agtctgcata gccctcatca actgaaacta caatggtatt
    69541 atcgtctttt tgcttagcct ctttttgatg acctccgcta caagcactta ataccatggt
    69601 cgaagccaat gacactactc caacaacacc tgcttttttc caatcccacg ccatagctat
    69661 ttacctccta aagggatgaa ctaaataaat attgtataac cgtaataaac tgcctcattg
    69721 attactagac tacaccaaat gctttgagat tattgattgc atttaggcag tgcatgatca
    69781 aatcagctta ttcaacttaa cttaaacgtt taagttaagt ttattataat gcaatcgctt
    69841 acagctgtca atagcaaatt tcatattttt taatctgatt tttctgccac taagtctagg
    69901 ataaaaaata gccgctcacg agatggccac atgattatca ccctagcaag taaactgtct
    69961 tgacatgttt actatcaaaa aaagattgag gaccataact aaaactagcc tttcctcaat
    70021 caagtctaaa ctaatattat tgaatagtaa aacagcaacc ctaagcccta gtataaagcc
    70081 tataatcctc ttcaatgagc attaacagcc caagtaaagg ccttaaagct tctctagaaa
    70141 tctcaagccc aagcctcatc agacaagcaa ggctaactga ctcctatagc aacaatcact
    70201 ccttctttaa aaccagctcg gcaatctgct tgcgcgcctg ccttgcctct cgtatcggga
    70261 agatcgcata agcatgaatc atctgctcag caatgatgag ctgattgaag tgcccctgct
    70321 ctgtcaagcg ctcatgcagg gtcataatat ctgggtaaaa aatctctttt gtcccgacaa
    70381 aggtgacaat ctttggcagg tcatgataat cgccatataa tgggctgaca tacggagacc
    70441 gcatctcttc tggactgcct gcccacaatt caccaatatc tcgaagccgc ctagcatcta
    70501 aataagcctc tactgcttca aaatgcttat aatcctgatt agcaaagcta acatctaacc
    70561 aaggagataa caggattaat tgctttggct gtggtgcagt ttgggtatct cttaggtatt
    70621 gcgccaaggc taaggccatg ccaccacctg aggagtcacc aataatgcta accttggcag
    70681 cgccattggc tagacaaagc tcctgataag ttttagcaag ctttgggtaa acctccttat
    70741 aggtggcata aggcgccttc tcaaaatttg ggaacaccag cttggcattg gttaaacgga
    70801 tcaaatgctt aatggtttta aagtgaaatg tctcagggcg acgcaaatag acactaccat
    70861 aaagatagta aatcactggc tgatcctgag aatcttggtc attgatcaca aaaacctgca
    70921 tgccatcaat cgtatattct gtggtgggaa tccccaatac cgcctctgga ttatccaagt
    70981 ggtagggaat gcgacgacgt ctttgcgtct caattccttc atagtcatca gcctttttag
    71041 agagcttata cttacgataa tcaaacatct tttcaagcag ccagctagaa aaggaccgct
    71101 tttgaccatg ctcaatcact aaaacagcaa tggctaaaat aagcaatatg acgatgatac
    71161 tcattaacaa ttctaatcct cattttctaa tggtctattg accctaaaat cctgctgttc
    71221 tatccgccca gtcctttgat aggaagtaag gatccagttg gtattcagat ggtggtgttt
    71281 gatcctctaa gaaaggaaca acctccttgt caaaggctag ccagccattc cagccaaggt
    71341 gaatggtatc ctccataaaa tacttgtctc cgccatttct ggaaaaatca gcaatgcgag
    71401 taaaaccctg cgaggttaac tgatgcttta tttttctgac tgccttttga tatctcctct
    71461 ggttcaagcc tgtataattt gcccacgctt gattaacagg tgtaataacg aaaagcacct
    71521 ctgttttacg ttttgcaaat tctgacaata ccagctgaaa atcattgtac tcaggtgaca
    71581 cagtgtaatt attacggcac tgaaaattct tataaagagg aaattgcggt gcaattcgct
    71641 tagaataaaa agcatttttg atgccaaagc gattatttga agttccttcc ttagcccgtc
    71701 tggctgctag ctcgctcaag cgctcataag aaaaggtttt aggcaaccct ttaacacgag
    71761 gcaaaatcct atcctcatag tttgttgaac gaccaaggaa gctaaacaag gactcctctc
    71821 ttaaggacag ctcctgctgc catttgagca gacgaatgtc ccatctactc aaggccttgc
    71881 cttgactaat tttccttaaa agctctgatt tagcaactcc cggattaatg tccagcattc
    71941 ttttagcggc aaattgtgat tccttatgac tagcctttgc ttttaagagg aaatcaatca
    72001 cctgactatt agatagatac aattgaaccg caccaggatc aatgccttgg ggggtaaacc
    72061 attgtgggga cacgacaaag actgcctttt ttccagttat ttcctgtgaa atctgctgca
    72121 tgccgtaata ttgtgataag gaagcagagc ctcttttccc aattaaaaac ggtctgtagg
    72181 agcgcttgta gcgttctgca agcactgatg ggtgcatgct atccatgcga ctccattcgc
    72241 tagagccaaa aaacggaaca aaacagtagt taggatctga caaggcctgc cttttaatca
    72301 agccattttt aaaggagcta tcattgattg ccactgcatt tgacttttcc tggcgcaatg
    72361 aatagctaag cttagtagga aagctgaata tggtaagaca aaccaagcca aaagcgatga
    72421 ttagaggacc taggattaac caaagccgtt taagcatgct gcaattcctc tatgccctga
    72481 ataattttat tggcagtgtt ccagtcctca cgtccaaact ctgaaattgg caccttaatg
    72541 ttaaagatag attcgatctc tacaatcagc tcaaccgttc ctaggctatc aagaacgcca
    72601 gcatcaaaca aatcctcgtc catcatatct gatacgtctt ccataaacaa gcgatcaaat
    72661 aagtcaatta cagtttcttt agtagacatt tttatactct ccttttttaa cgtaacggtc
    72721 tgttaaacca aagctcattt aagaagcctg aaaataacag aagtgagaac aagacaacgt
    72781 ggaaagtgac cacgattgat aaagcatgaa atgccttacc ctcaaacaaa ggcttaagcc
    72841 cttgcttttt ccgacgacga ttgatttcct ttttcttacg aagccaagcg tcgtttacaa
    72901 tcaagccaat accatgaaac agaccgtaag caatataata ccaggtcaag ccatgccaaa
    72961 gtcccatcac cagcatgttg atcaggtaag caaagcccga agtcacattt cgattcttaa
    73021 aggtcttgtg cttgattaag agatggacca atcgcatgaa gacaaagtct ctaaaccaga
    73081 aggataggct catgtgccac ctgttccaaa actcttttaa atttggtgat aagaagggct
    73141 tattgaaatt ttcaggtgtc ttaatcccca gtaaataaga caacccaatc gcaaacatcg
    73201 agtagccagc aaaatcaaaa aagagattaa gcccataaag gtacatgaca tagatcgtct
    73261 ctttattaaa gtagccacct acagtcagag ccttattttc agcaaggggc aatagcagcc
    73321 cacccaagca ataagagata atatgcttgt acagaaagcc cagcatgaga tacatgacag
    73381 ccttattgag catatcaagg taaacatcac gactaggaag cttggtgtaa tcctcttgaa
    73441 accttctgaa gcgatcaatc ggcccgcttg aaaaagtcgg aaagaaaatc ataaagcgta
    73501 gaaaatcctt tagactaaaa tctgtcaaaa ccccatcacg catttcaatg atcatcccaa
    73561 cgcttttgaa agttaaatag gaaataccta agaagctaaa gaaagacctc gttagactga
    73621 cagcgataaa tgggcttacc ttcacacaaa tcaaaggaaa tagactggct aaaatgctaa
    73681 gatagaaaac ccacgctgca tttgcctttt gacgatagtg cttgtaagcc aaaacactga
    73741 tggtttgcca aattagatag gctaaaaagg caagcaattg ctgatagtgt tccccaccaa
    73801 acatgagcaa aataaagatt aggctgacaa agctttcata cgtcgaaaaa cgcctttgct
    73861 taaaaatccc aataataact ggaagaaaag caatgatgag gtagacaaaa taaatcggat
    73921 tgccataagg ctccatataa ggtatgtgat gaaacaaggt cgtcattgat gattaacctc
    73981 gttaatcaag aatttgatat cgattttgcc atttggtgtc aatgggagct tttcacgata
    74041 aataaactta gacggcatca tataggccat catatgatcc ttaacagagg ctttaatggc
    74101 tttggtaata tccaaatctc tcgcaaattg ctccctcacc ccgtccttca agacaacata
    74161 agctaagaga ttttggacct tatgctcttt gttatacctt ggtactgcta ctgctgattc
    74221 aaccagcggt gattggttta gctgctgcga cacatcttct aattcgatgc ggtaacctgc
    74281 atatttgatt tgaaagtcta atcgtccacc ataaagtaac acattgtcct cagtaaatga
    74341 tcctaaatct cccgtatgat aagcaggcat gccattaaag gtaaagaagg cttcagctgt
    74401 cttttcagga ttgttgagat aacccttaga aactgctgga cccgttacaa taatctctcc
    74461 ctgttgcccc ggctccagag cattgccagc ttcatcaatg atataagtag gcgaatccgg
    74521 ctttggatag cctatcggca agcgtgtgta agtctctatc atatctttag tgattgaaat
    74581 cgctgataac gccaccgttg cctctgttgg accataggca ttgataatgc gtgcgtctgg
    74641 aaagcgttca aatagcttcc ttgcagttga tactgtcagc tcctccccat caaaataaaa
    74701 atgggtcagc tttggcatct tctcctgaca aaaatcatca ctaagcattg ccatgtcggc
    74761 aaaggacggt gttgaggtcc aaatccctat cggcagctcc gcaattgtgc taaacaagcg
    74821 cttaaaatct gacaccattt ccttgggtaa agcaaacaat gtcccaccta aaactaaggt
    74881 cggcgcccaa tacatcaccg acaaatcaaa ggaataagga ggctgagcca gcatctgtgg
    74941 tctctcagga atagcaaact cagcatcctc aatcatccaa ttagtaaagc tcaaaagatt
    75001 ggcatgcgaa atttgcactc cctttggctg tcctgtcgtt ccagaggtga agataatata
    75061 ataattgtca tctcccttga caggactggt catggtaaag gctgccttgg ctgctttagc
    75121 tgcctctatc tctgctaagc taaccaccct aattgcatca atactaaccg gcagctcctc
    75181 aatagcaatg ataagacttg gctgagcaat ctcaataata gacaaaacac gctctggcgc
    75241 cgaatgaaca tcaacaggaa tgtaagcatg acctgtcttt gtcaaggcga caaaagaagc
    75301 cagcatgtca tagctttgag ccccaaaaac taaaacgggt gatttttcac ctagctttaa
    75361 gctctcaata aagcctgcta tgctatctga gtcctccttt agctgcccat agctacggcg
    75421 ctctcccaag caatcataaa ctggaaaatc cggctgcact tgtgcaaaat actcaattgt
    75481 ttcaatcata tcgttaacca tcagacaatc tcctaaaatt cattataaat aaaattactt
    75541 tgaccatgcc ctaggtaacc aaaaaaataa acgagcagca tcaaaatcac gtaaaacaat
    75601 gctatcttcc caacaaaaac gaaaatagct cgcagtcttg acttgttttt taacatactt
    75661 accttcttgt attagtgaaa taatgtacta agaaattcta
//
LOCUS       DARYSY010000002        60893 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYSY010000002 DARYSY010000000
VERSION     DARYSY010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60893
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            277..513
                     /locus_tag="TVR04_000071"
                     /pseudo
     CDS             277..513
                     /locus_tag="TVR04_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679805.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            614..989
                     /locus_tag="TVR04_000072"
                     /pseudo
     CDS             614..989
                     /locus_tag="TVR04_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TNT domain-containing protein"
     gene            990..1583
                     /locus_tag="TVR04_000073"
     CDS             990..1583
                     /locus_tag="TVR04_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268798.1"
                     /translation="MIYKESYIHWLTDFLGASLVSKGDNVSVSDGVDIIYCMEKREDK
                     YDISISERGKVITQHRVLNSKLARLYYILLVKKALTTIKYPLLNSIGNVDSEELLRAQ
                     LNSEGLENYYSINKNGIGKVNFQNIGKDRLYYLDNKNNAYDIFFVSSKVLSVFYTSIV
                     RLKWYEKWIEQLSSIEDISSDLYPVLLGFSHEGIEIL"
     gene            2040..4493
                     /locus_tag="TVR04_000074"
     CDS             2040..4493
                     /locus_tag="TVR04_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEL1268799.1"
                     /translation="MILAHYQGKTDLEPAKEQSLEEHSFQVAELARTAATSIKQGDLV
                     FLLGLFHDLGKAEYRFQEKLLKKPNSHVDHAYAGARYLYDEIGKVLLGHVQQYPDSKS
                     LVLYFRDIVAYVISAHHGMYDLRMTEPTEEASRFAHNKLLHRIFQERPDYHYQKDVLP
                     FVEVLEKSLPRYGYDHLADLITRAFYNFQLAWDRLDMADASEQDYYSGCFVRLYLSLL
                     KNADVLDTINAYETVIEPLTEEKQEELRISYLEAVESLYASFGQSKLRLNAIRNKLAE
                     RVKGRGREDSTGIYRLNLPTGAGKTNLSLRYATHQMVYQQKKHFLYVTPFLSVLEQNA
                     LAMKQVIGEEGVLEHHSNVVREIDNTNQNNDDADEDRDSLRREYLIDSWDSPVVLTSM
                     VQFFQTLFKTRSAHLRRFSSLIDSVVILDEVQSLPIEVTTLFNLTMTFLSRVMQTTLV
                     LCTATQPAYDSESITHTLTYGGSKAEEADIVTVTDEEQLVFARTELCKLSDSDEKTSL
                     VELAQTILEQEMSTLVILNTKPAVERLYQLLRDQTERPLYQLSTNMCPKHRLDVIAEI
                     KSRLPNNVPLICVSTQLIEAGVDIDFERVIRSYAGIDSIVQAAGRCNREGRRPIGQVL
                     LVNLTDDEENLSYLKEIKHKKDATETILYQKTSPIDIAALNEAFFNCYYENNKKRLDY
                     PLGDNESVYQYLSSNAPSNIKKGKLRQAFKTAGQKMDLIQDQSIGVFVYYDDGVGRER
                     LEALEEQLLKSSYPSSEELKAIKAELKALQPYTITLRDNHELLKATRSYLSGQILILQ
                     EHYYNQTFGLTKEADSFIL"
     gene            5250..5969
                     /gene="cas5c"
                     /locus_tag="TVR04_000075"
     CDS             5250..5969
                     /gene="cas5c"
                     /locus_tag="TVR04_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEL1268800.1"
                     /translation="MRVRGDIALFTNPATKGSSERSSYPVPTRQALQGIVDAVYHKPT
                     ITNVVTEVKVINQIQTELHGTRALLKDYGADLSYVSYLSDVEYLIKYHFVWNENRPDL
                     VKDRLPNKHEAIMERSLRKGGRRDVFLGTRECLGLVEAISQEEYETAQIASEHANQEI
                     DLGIMFHSFAYPTDRKEPLRSYFTRTVMTNGTIHFKEQAECEIVNTLSSYTFKPAGPI
                     KPVEEEFEGYQLDTIREAGGQ"
     gene            5969..7852
                     /gene="cas8c"
                     /locus_tag="TVR04_000076"
     CDS             5969..7852
                     /gene="cas8c"
                     /locus_tag="TVR04_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEL1268801.1"
                     /translation="MDFFTSLLRAYEHAEDIGLVDNQEQSGTILLPIYHTNRRSNGKD
                     TIVVQLDKTGQFMKAEYLADGETIIFPVTAESVARSGKNPAPHPLVDKLTYFVSAHNQ
                     EQYETYHQQLEGWINACQDKQVMSYLSLIQQFILKEDFLDLICQSLFGKRLSRNGLKV
                     TYALSEEKEKTVDLSACFLTFQIAQFIGFKTVSVTNFTALHKDYIAYLMSKQTANTIC
                     NISGQKEVLATKHRGLLGNAKLISVSNHAEAYKGRFRERDDVFRVGNQTSEKLHLMAK
                     YFLEHEQTHVWLGSGQHMINWFSDDLANDSQLNITQALLLDPFDDEETFLSTPMISEE
                     NKSINRSFITGQRQFSDNASYYIAILNKTNDGRIALKYFRQLQASSLLKNLAVWQENY
                     SWELQRKGNQFVQKLPSFKEIILAAYGVDRDRSLELDNDNFRSDQYQRLVTSLIDGKP
                     LPDTIVKKLEANIKQRQKYRKHWHQVEHISLAILHKQNGEEFTPMLDRDNTNRSYLFG
                     RLLGIYELIEKSRNNSKGRAKDELKRITNAERYWTAYANRPASLMRNLEDKIYPYSEY
                     LKINEAGLWSKLEKEREEIIALLTSSLETTDFNKPLDYRFIFGYYAEKKYFYTPKDES
                     EDA"
     gene            7853..8701
                     /gene="cas7c"
                     /locus_tag="TVR04_000077"
     CDS             7853..8701
                     /gene="cas7c"
                     /locus_tag="TVR04_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEL1268802.1"
                     /translation="MLEHKIDFMVTVEVKEANANGDPLSGNMPRTNAKGYGLMSDVSI
                     KRKIRNRLQDMGQSIFVQANERIEDEFRSLENRFSAQFDKNDKDDDIERRANELWLDV
                     RSFGQVFTYLKKSIGVRGPVSISMAKSLEPVVISSLQITRSTNGMEPKGDSSRSSDTM
                     GTKHFVDYGIYVIKGSINAHFAEKTGFSEEDADIIKQALVSLFENDASSARPEGSMRV
                     REVFWFTHSSKLGNVSSARVFDLLVFDMETPDKDRYEAYGIHLDEEKLAAYQAKGLTV
                     EVLEGL"
     gene            8703..9374
                     /gene="cas4"
                     /locus_tag="TVR04_000078"
     CDS             8703..9374
                     /gene="cas4"
                     /locus_tag="TVR04_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEL1268803.1"
                     /translation="MVYVEDDYLMLSGIQHFQFCKRQWALIHIDQQWVDNEATAHGQI
                     LHTRADNPYIREKRKDFFLSRAMHISSARLGLYGVMDVVEFYKDDSGVTVKGKRGRWL
                     PRVVEYKRGKPKKDRRDIVQLVAQTMCLEETLNCQIAEGSLYYHSVNKKVQIAITDEL
                     RREVQELANQMHRFYGAKELPKAEYFKNCQLCSLVEVCKPRISKKVRNVDRYIAAAMV
                     SEEII"
     gene            9371..10396
                     /gene="cas1c"
                     /locus_tag="TVR04_000079"
     CDS             9371..10396
                     /gene="cas1c"
                     /locus_tag="TVR04_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEL1268804.1"
                     /translation="MKKLLNTLYLTQEDYYITKEGDNIVIKQDGKTVSRFPFRIIDGV
                     VCFSYLGASPALIKLCTENQINLSFHTPQGRFCGRYVGATNGNVLLRREHYRLADRDE
                     SLEYAKRFILAKISNARKYLLRFRRDHRDQIDGKLFEEVNGELIWALEMVQATDNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKAFTFGGRSKRPPLDRVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIIDRFVFSLINKGQLTKKHFDVK
                     ESGSILLTEKGRVTFIELWQKRKHMEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDID
                     SYPPFMI"
     gene            10407..10700
                     /gene="cas2"
                     /locus_tag="TVR04_000080"
     CDS             10407..10700
                     /gene="cas2"
                     /locus_tag="TVR04_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEL1268805.1"
                     /translation="MMVLVTYDVNTETASGRKRLRQVAKLCVDYGQRVQHSVFECSVT
                     PAEFVEIKHKLTTIIDTEVDSIRFYLLGKHWQNRVETLGRSDSYDPDIGVLLL"
     repeat_region   10849..12334
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=10849..10880
                     /rpt_unit_seq="gtctcgccccatacgggcgagtggattgaaat"
     gene            complement(12519..13824)
                     /locus_tag="TVR04_000081"
                     /pseudo
     CDS             complement(12519..13824)
                     /locus_tag="TVR04_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            14205..14915
                     /gene="ccdA2"
                     /locus_tag="TVR04_000082"
     CDS             14205..14915
                     /gene="ccdA2"
                     /locus_tag="TVR04_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1268806.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFVILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVV
                     MGLLLMTGNLNSLSGLFE"
     gene            14929..15579
                     /locus_tag="TVR04_000083"
     CDS             14929..15579
                     /locus_tag="TVR04_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HEL1268807.1"
                     /translation="MKKTTFLTTGLACLALLTACSSKDKMAMNDNKKDHMTMTDDKSK
                     MKKDQKDMMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGILAKKHIGYAKKSEIEKTLKEIK"
     gene            15597..16709
                     /gene="msrB"
                     /locus_tag="TVR04_000084"
     CDS             15597..16709
                     /gene="msrB"
                     /locus_tag="TVR04_000084"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1268808.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVKVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGVYYTDPS
                     DLTTIDMVFQETASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            16977..17717
                     /locus_tag="TVR04_000085"
     CDS             16977..17717
                     /locus_tag="TVR04_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1268809.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            17714..19432
                     /locus_tag="TVR04_000086"
     CDS             17714..19432
                     /locus_tag="TVR04_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1268810.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDQLSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVY
                     HPKNTVYSSAKEMAAMKPYLAVTDGYTRPKDYFVYQRVIPDSQWTLVGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMVSVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVSEADRHVILSVWDNGK
                     GISLADDSSQALLERGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            19471..20559
                     /locus_tag="TVR04_000087"
     CDS             19471..20559
                     /locus_tag="TVR04_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1268811.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            20574..21278
                     /locus_tag="TVR04_000088"
     CDS             20574..21278
                     /locus_tag="TVR04_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1268812.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNAASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            21538..22026
                     /locus_tag="TVR04_000089"
     CDS             21538..22026
                     /locus_tag="TVR04_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1268813.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLVIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(22536..23009)
                     /locus_tag="TVR04_000090"
     CDS             complement(22536..23009)
                     /locus_tag="TVR04_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1268814.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            23150..23830
                     /locus_tag="TVR04_000091"
     CDS             23150..23830
                     /locus_tag="TVR04_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1268815.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     SYFLQYTT"
     gene            24100..25335
                     /gene="arcA"
                     /locus_tag="TVR04_000092"
     CDS             24100..25335
                     /gene="arcA"
                     /locus_tag="TVR04_000092"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1268816.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEALRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            25345..25776
                     /locus_tag="TVR04_000093"
     CDS             25345..25776
                     /locus_tag="TVR04_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1268817.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSELSAQSFYEGIGYQAFGEPYDEDGEPCQSVEKYL"
     gene            25791..26804
                     /gene="argF"
                     /locus_tag="TVR04_000094"
     CDS             25791..26804
                     /gene="argF"
                     /locus_tag="TVR04_000094"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1268818.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            26967..28460
                     /locus_tag="TVR04_000095"
     CDS             26967..28460
                     /locus_tag="TVR04_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1268819.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKFLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFGIKLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLSTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            28477..29808
                     /locus_tag="TVR04_000096"
     CDS             28477..29808
                     /locus_tag="TVR04_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1268820.1"
                     /translation="METYIQSRHQEACVAAIKKIVSYPSVLNEGENGTPFGQAIQDVL
                     EATLALCQDLGFKTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHTDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSARLNLEVGQAYNVVPARASYQG
                     DKLEALGEELDRLGFEYVVKDGELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEVTEVRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYREKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENERIVLADAYRSMDIYAEAIYRLTR"
     gene            29826..30776
                     /gene="arcC"
                     /locus_tag="TVR04_000097"
     CDS             29826..30776
                     /gene="arcC"
                     /locus_tag="TVR04_000097"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1268821.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIVAG"
     gene            30996..31988
                     /locus_tag="TVR04_000098"
     CDS             30996..31988
                     /locus_tag="TVR04_000098"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1268822.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELSSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            32158..32697
                     /gene="rsmD"
                     /locus_tag="TVR04_000099"
     CDS             32158..32697
                     /gene="rsmD"
                     /locus_tag="TVR04_000099"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1268823.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIEMTKASQQFTLLKMDAER
                     AFDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDEVMIVCETDRSVALPEEIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            32687..33187
                     /gene="coaD"
                     /locus_tag="TVR04_000100"
     CDS             32687..33187
                     /gene="coaD"
                     /locus_tag="TVR04_000100"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1268824.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLREAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMANHDLQPISSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKI"
     gene            33165..34202
                     /locus_tag="TVR04_000101"
     CDS             33165..34202
                     /locus_tag="TVR04_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1268825.1"
                     /translation="MKTIKKFKWWLIGLVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TAQDAISYLKK"
     gene            34763..35377
                     /locus_tag="TVR04_000102"
     CDS             34763..35377
                     /locus_tag="TVR04_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1268826.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            35381..36463
                     /gene="rlmN"
                     /locus_tag="TVR04_000103"
     CDS             35381..36463
                     /gene="rlmN"
                     /locus_tag="TVR04_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1268827.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFLAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDQRGQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            37735..38265
                     /locus_tag="TVR04_000104"
     CDS             37735..38265
                     /locus_tag="TVR04_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1268828.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            38638..38871
                     /locus_tag="TVR04_000105"
     CDS             38638..38871
                     /locus_tag="TVR04_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1268829.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            38846..39817
                     /locus_tag="TVR04_000106"
     CDS             38846..39817
                     /locus_tag="TVR04_000106"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1268830.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMVVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            39827..40207
                     /locus_tag="TVR04_000107"
     CDS             39827..40207
                     /locus_tag="TVR04_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1268831.1"
                     /translation="MSPLTIIGWVLFAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPTQQFATSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            40613..42454
                     /gene="typA"
                     /locus_tag="TVR04_000108"
     CDS             40613..42454
                     /gene="typA"
                     /locus_tag="TVR04_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1268832.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLAELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            42539..42793
                     /locus_tag="TVR04_000109"
     CDS             42539..42793
                     /locus_tag="TVR04_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1268833.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            42939..44297
                     /locus_tag="TVR04_000110"
     CDS             42939..44297
                     /locus_tag="TVR04_000110"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1268834.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGAQSALLAGNIGFPASEVAQAATA
                     KDTLVMELSSFQLMGTEQFHPHIAVITNLVPTHLDYHGSFEDYVAAKWHIQYRMTDKD
                     YLVLNADQELVKPLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISKTLSHFSGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSRVILIAGGLDRGNEFDELVPDLVGLKKMILLGESVERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKPGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EA"
     gene            44297..45379
                     /locus_tag="TVR04_000111"
     CDS             44297..45379
                     /locus_tag="TVR04_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1268835.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDNGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDAFKVGFGIVQSLLIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLVKLKHVG
                     AVTKVTAPKSRSVASKQLTAVSEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSRHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMT
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            45380..46573
                     /locus_tag="TVR04_000112"
     CDS             45380..46573
                     /locus_tag="TVR04_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1268836.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGETVSKADQEEGTDEAEEKAEVDQVGADEGEQLPEASEQEVPSPKDKPLKV
                     PKEKSPRQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDS
                     GIKSSDYWITLLASPGSYENAILKANPWVKKVALRYGFPNHFRFDVTEFDIIAYARVA
                     EGFQPILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVS
                     SANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTT
                     AEIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTE
                     QANQQ"
     gene            46785..48149
                     /gene="ftsA"
                     /locus_tag="TVR04_000113"
     CDS             46785..48149
                     /gene="ftsA"
                     /locus_tag="TVR04_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1268837.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNEARGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            48173..49501
                     /gene="ftsZ"
                     /locus_tag="TVR04_000114"
     CDS             48173..49501
                     /gene="ftsZ"
                     /locus_tag="TVR04_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1268838.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRHSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            49504..50175
                     /locus_tag="TVR04_000115"
     CDS             49504..50175
                     /locus_tag="TVR04_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1268839.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            50188..50850
                     /locus_tag="TVR04_000116"
     CDS             50188..50850
                     /locus_tag="TVR04_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1268840.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            50855..51109
                     /locus_tag="TVR04_000117"
     CDS             50855..51109
                     /locus_tag="TVR04_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1268841.1"
                     /translation="MIFILLILLKLIKVYSYLLLAYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLI"
     gene            51109..51903
                     /locus_tag="TVR04_000118"
     CDS             51109..51903
                     /locus_tag="TVR04_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1268842.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIARARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            51913..52668
                     /locus_tag="TVR04_000119"
     CDS             51913..52668
                     /locus_tag="TVR04_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1268843.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            52939..55737
                     /locus_tag="TVR04_000120"
     CDS             52939..55737
                     /locus_tag="TVR04_000120"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1268844.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GLLDTDTYIVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYDKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQKYGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINDAYEHYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDIILE
                     EWEAFMTLRTQAQKALEEARYDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSATN"
     gene            complement(56396..56698)
                     /locus_tag="TVR04_000121"
     CDS             complement(56396..56698)
                     /locus_tag="TVR04_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1268845.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(56760..57206)
                     /locus_tag="TVR04_000122"
     CDS             complement(56760..57206)
                     /locus_tag="TVR04_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1268846.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIETGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(57353..59608)
                     /locus_tag="TVR04_000123"
     CDS             complement(57353..59608)
                     /locus_tag="TVR04_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1268847.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYTGNQKAQQQSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGQHGGGHNGGYRPN
                     HTQPAQETNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
                     EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLME
                     EIRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRII
                     EKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQSAIEAAANLSNRYI
                     QDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYF
                     RDQIAKYKEMQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADL
                     KKHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFG
                     SADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKA
                     HPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTN
                     SVLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQ
                     KVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDLRAVLTSNGHIIIK
                     PVVKSQAKQAD"
     gene            59890..60120
                     /locus_tag="TVR04_000124"
     CDS             59890..60120
                     /locus_tag="TVR04_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1268848.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(60564..60665)
                     /locus_tag="TVR04_000125"
                     /pseudo
     CDS             complement(60564..60665)
                     /locus_tag="TVR04_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        17496 a        11258 c        14328 g        17811 t
ORIGIN      
        1 cttattggaa ctaggttatt gacaaaaatt aaaaatgtca ggaatgatat ttattacatt
       61 ccatttcatg agaaatttga agcaattaga gagatacgtt atctatatag ccgtaaagat
      121 atcattcaaa taggagaagt tatccatcct gattttatat aaacgaacta gatttaacag
      181 gtggtgaaat aatagttgct gttaacttat ttcgacattt gttgttatta agtcttttac
      241 aaataaaaaa tagctattgt cgccagaaga ttcagcttga atgagccgat agcagttgag
      301 gtgacgaaac cgacctacaa ccgccagcag cttttgaaga accttgagaa cagcaggctg
      361 gcaacagaga gatcaaggtt taagagctat gtagcaagag aaaaattcac gataactctt
      421 gcggtcatga gtcctgagga tagccaacgc tacattcaat ggcacaaata cgcaaaggcg
      481 ggtattgagc ctgtggatag gttaaggtta atgggttggg atcgaccacc acactaggat
      541 ctgatttatg cttgaaaaat aaaagggtct atgataatcc taagtatttt gatcctaaaa
      601 taggaaatga atattggcca gagataatgg tgatcctaac ttagatagat ttttaaatgg
      661 tgaatttaat aatactaaat tacaatcagg caaaaaaata gatagatttg gttcgaatta
      721 tggatcgttc tttggttggt gaagtaggtg attctagggc attacgtgca atgtctccta
      781 attctgattt tagtaactat aatcaatatg aagtcttaga agaacttcct gttagagaag
      841 gaaagattgc accttggttt gatgagccag gtggagggag acaatataaa ttggattcgg
      901 actttgttaa tcagctacag tctttattgc aagatggtac accgttaatt gataaattaa
      961 ttgaattagg ttatttaagg agaatataaa tgatttacaa agaaagctat attcattggc
     1021 taacagattt tttaggagct tcacttgtat ccaaaggtga taatgtgagt gtaagtgatg
     1081 gagttgatat catttattgc atggagaaga gagaagataa atatgacatc tctatcagtg
     1141 aaagaggaaa agttattaca caacatagag tattgaactc aaagctagct cgattatatt
     1201 atattctctt agtgaaaaaa gcactgacga caattaaata ccctcttctt aatagtattg
     1261 gaaatgttga tagtgaggag cttttacgag ctcaattaaa ttcagaggga ttagaaaact
     1321 attactcaat aaataagaat ggcattggga aagtcaattt tcaaaatatt ggtaaagata
     1381 gactatatta tcttgataat aaaaataatg cgtatgatat attttttgtt tctagtaagg
     1441 tgttaagtgt attttataca tcaatagttc gattaaaatg gtatgaaaag tggattgagc
     1501 agttatcctc tattgaagac ataagttcag acttgtaccc ggtattatta gggtttagtc
     1561 atgagggaat tgaaattctg taataataag ctatttattt tcggttatag tcataaaact
     1621 gataagttaa actaattccc ccagtacaat tagttttgtg tcatttatga gaagaggtta
     1681 cataacttag aaaaggacag ccagcctatt tcaaagacca ataaggcgct atagggctga
     1741 cagtagtttt ctgtgacctg tcatacctaa gctctgagtc tagatgtaaa gtctccggtg
     1801 gtgaaagtta aaaaggttta gcaactgtta tgatggtgaa atatatggtt ttggattgac
     1861 gctgtttgct aatctatcct cctatttgtc agaccttaga aggtaatggt ataagcacta
     1921 agatttgttt acatttttat aggaaaatgt aatgtatgcg tttacatttt gtgagaaata
     1981 ggttaaacta ttattgtgaa aagattattt tgtattatgt gtcaaggaga aggtcatata
     2041 tgatattggc tcactatcaa ggcaaaacag atttggagcc tgcaaaagag caatcgctag
     2101 aggagcattc ttttcaagtg gctgaactag caaggactgc agcgacttct attaaacaag
     2161 gagatttagt atttttactg gggctttttc atgatttggg taaggccgag tacagatttc
     2221 aagaaaagct attgaaaaag cctaatagtc atgttgatca cgcttacgct ggtgcacgct
     2281 acctttatga tgagattggt aaggttttac taggccatgt tcagcaatat ccggatagta
     2341 agtcattagt gctttatttt agagatattg tagcttatgt tatttcagcg catcatggca
     2401 tgtatgactt gcgaatgaca gagccaactg aggaggccag ccgatttgct cataataagc
     2461 tattgcatcg tatatttcaa gaaaggcctg attatcacta ccaaaaggac gttcttcctt
     2521 ttgtagaagt ccttgagaaa tcattgcccc gttatggcta tgatcattta gcggatctga
     2581 taacacgcgc tttttacaat tttcagttgg cgtgggatag gctagatatg gcagatgcca
     2641 gtgaacagga ttactatagc ggctgttttg tccgactcta cttatctctt ctaaaaaacg
     2701 ctgatgtttt agatacgata aatgcttatg agacggtgat agagccttta acagaagaaa
     2761 agcaagaaga gctgcgcatc tcctatcttg aagctgttga aagtctatat gctagctttg
     2821 gccagtcaaa gctaagatta aatgctattc gcaataagct tgctgagcgt gtcaaaggtc
     2881 gtggcagaga ggattcgaca gggatctacc gtttgaattt accgacagga gcaggtaaaa
     2941 caaacttgag cctacgttat gcaactcatc agatggtcta tcagcaaaag aagcactttt
     3001 tgtacgtgac gcctttttta tcggttttgg agcaaaatgc tcttgcaatg aagcaggtta
     3061 ttggtgagga aggtgtctta gagcaccact caaacgtggt acgagaaata gacaatacca
     3121 atcaaaataa tgatgatgca gacgaggata gagacagctt acggcgagaa tatttgattg
     3181 acagctggga tagtccggtg gtattgacgt caatggtcca atttttccag accttgttta
     3241 aaacaagatc agctcatttg aggcgctttt caagcttaat agacagtgtt gtcattcttg
     3301 atgaggtcca atcgttgcca attgaagtga cgaccttatt taatttgacg atgacttttt
     3361 tgagtcgtgt aatgcagaca acgcttgtgt tatgtacggc gacacagcca gcctatgatt
     3421 cagaaagtat tactcatacc ttaacttatg gcggcagcaa ggcagaagag gctgatattg
     3481 tgacagtaac ggatgaagag caactggtct ttgctcggac agagctttgt aagctatcag
     3541 acagcgacga gaaaaccagt ctagtagagc tggcacagac tatcctagag caggagatgt
     3601 caaccttagt tattttgaat actaagccag ctgttgaaag gctctatcag cttctgaggg
     3661 atcaaacgga acgccctctc tatcagctat ccactaatat gtgtcctaag catcgactgg
     3721 atgtgattgc ggagattaag agtcgcttac ccaataacgt tcccttgatt tgtgtgagta
     3781 ctcaactgat tgaagcagga gtggacattg attttgaacg tgttattcgc tcttatgctg
     3841 gtattgattc tattgtgcag gcagctggtc gttgtaatcg agaaggcaga cgtcctattg
     3901 gtcaagtgct cttggttaac ctaactgatg atgaggaaaa cttatcttat ttaaaagaaa
     3961 taaagcataa aaaggatgcg acagagacaa tcttgtatca aaaaacatca cctattgata
     4021 ttgctgcttt aaatgaggct ttttttaatt gctattatga gaacaataag aagcgtcttg
     4081 attatcctct gggagacaac gaaagtgttt atcaatattt gagtagcaat gcgcccagca
     4141 atattaaaaa aggaaagctg cgacaggctt tcaagactgc aggtcagaaa atggatttga
     4201 ttcaggatca gagtattggt gtttttgtct attatgacga tggagttggg cgagaaagac
     4261 tagaagcact tgaagagcaa ttgctaaaaa gcagttaccc tagcagtgag gaattaaagg
     4321 ccattaaagc agagctgaaa gctctgcagc cttacactat tactctacgg gataatcatg
     4381 agctattgaa ggcaactcgc tcttacctca gtgggcaaat cctgatcctt caggagcatt
     4441 attataatca aacatttgga ttaacaaaag aagcagacag ctttatcttg taggagaaga
     4501 tatagctgcc tgccaagtcg actagatagt aactttaaca ttattgcaat ccacatagat
     4561 cagaacacct atgataacag tatgtgtata gtatagcaaa atagcattag tgaggcaaat
     4621 aatatataat atagttaatt tgacattgaa gaacgttata tagtgtgcta taatagccct
     4681 ataatctatt aaaggaggtg tgtattatca atagggtatt tgacttgctg attaaattag
     4741 tggagcattt atcaagtatt tttgtctctc tgtccatatt tttatccatt ttacgcagca
     4801 aaaagaaaga ataggagatt agtgagaaga gctgataggc tcttctcacc caatttctta
     4861 tctcagcctt ataatagcta tagtagaaac agcgtctctg actcgtttct aaaaagtaat
     4921 aaggctgtgg ttagagcctt tctgaactag tcaagtagct ttgcaggaca aatatacgaa
     4981 aaaacattag tgaaaaacga tattttttac cttttatttt cagatttttt aaaacaagca
     5041 ttgctttttt gatattcttg ttaaaagact gctatctgaa atcaactgtg actgtatcaa
     5101 tagttgaaaa aatttgtttt atatgcttgt cccagtcttt gaaagagtta atacacatgt
     5161 gatccgagta taatacttgg gctttggcag tagctaactg cacaaataat aaggaggaat
     5221 ggtcattgta cagatctcga catttttaca tgcgtgtccg aggcgatatc gccttattta
     5281 cgaaccctgc aaccaaaggc tctagtgagc gttctagcta ccctgtcccg acgcgacagg
     5341 ccttgcaggg cattgttgat gcagtctacc ataaaccgac tatcactaat gtggtcacag
     5401 aggtcaaggt aatcaatcag attcaaacag agctgcatgg tactagagcc ctgttaaagg
     5461 attatggcgc agatttgagc tatgtatctt atcttagtga tgtggaatat ctaataaaat
     5521 atcactttgt ctggaatgag aatagacctg atttggttaa ggatcgcttg ccgaataagc
     5581 atgaagcgat tatggagcgt tcactgcgta agggtggcag acgtgatgtc tttttaggta
     5641 ctcgtgagtg cctaggcttg gttgaagcga ttagtcagga ggaatatgag acagcacaaa
     5701 tagcttcaga gcatgctaat caagagattg atttgggaat tatgtttcat tcctttgctt
     5761 atccaacaga tagaaaagag cctttacgtt cctactttac acgaacagtg atgactaatg
     5821 gaacgattca ctttaaagag caggctgagt gtgaaattgt gaatacctta tcaagctata
     5881 cttttaagcc agcaggaccg atcaaaccgg ttgaggagga gtttgaaggg tatcagctag
     5941 acacaataag agaagcagga gggcagtaat ggattttttc acctcgcttt tgcgtgccta
     6001 tgagcatgct gaggatattg gattggttga taatcaagag cagtctggaa caatcctgtt
     6061 accgatttac cataccaatc gacgttcaaa tgggaaggat acgattgttg ttcagttgga
     6121 taaaacaggt cagtttatga aggcagagta tcttgctgat ggtgagacaa tcatatttcc
     6181 agtgaccgct gagtcggttg caaggtctgg gaaaaatcca gcccctcacc ccttagtaga
     6241 taagctgacc tactttgttt cagcgcacaa ccaagagcaa tatgagacct atcatcagca
     6301 actagagggc tggatcaatg cttgtcagga taagcaggtg atgtcctatc tgtccttgat
     6361 tcagcagttt atcttaaaag aggatttttt ggacctgatt tgccaatctc tttttggaaa
     6421 gcgacttagt cgtaatggct taaaagtaac ctatgctttg tcagaggaaa aggaaaaaac
     6481 agttgatctg tctgcttgct ttttaacatt tcagattgct cagttcatcg gctttaaaac
     6541 tgtatctgtg actaatttta cggccttaca taaggattat attgcttatc taatgtctaa
     6601 gcaaacagct aatacgattt gtaatattag cggtcaaaaa gaggtcctag caacaaagca
     6661 tcgcggctta cttggtaatg ccaaattgat ttctgttagt aaccatgcag aggcttataa
     6721 ggggcgcttt agagaaagag atgatgtttt tagagttggc aaccaaacat cggagaaact
     6781 gcatctcatg gccaaatatt ttttggagca tgagcagacg catgtttggt taggctctgg
     6841 gcagcatatg attaattggt ttagcgatga cttagcgaat gatagtcagt taaatattac
     6901 tcaggcttta ttgctggacc catttgatga tgaggaaact tttttgtcta ctccaatgat
     6961 tagcgaagaa aataaaagca ttaatcgttc ctttatcaca gggcaacgtc aatttagtga
     7021 taacgcttct tattacattg ccattttaaa taaaaccaat gatggacgta ttgccttgaa
     7081 atatttccgg caattgcagg cttctagtct tttaaaaaac ttagctgtct ggcaggaaaa
     7141 ttattcatgg gagctccagc gtaagggcaa tcaatttgtt cagaaattac ctagctttaa
     7201 agagattatt ttggctgctt atggggttga tcgtgatcgt tctttggagc tggataatga
     7261 caattttcgt agtgatcagt accaacgtct ggtaactagt cttattgatg gaaagccctt
     7321 accagacaca atcgtaaaga aattagaagc caatatcaag caacggcaaa aatataggaa
     7381 gcattggcat caagtcgagc acattagcct tgctatttta cataaacaaa acggagagga
     7441 gttcacacca atgttagaca gagacaatac taatcgttct tacttgtttg ggcgtttgct
     7501 aggaatttat gagttgattg aaaaatcacg taacaactct aaggggaggg ctaaagatga
     7561 gctgaagcgt attaccaatg cagagcggta ttggacagcc tatgctaatc gtccggctag
     7621 tttgatgaga aatttggagg ataagattta tccttatagc gaatacctca agattaatga
     7681 ggctggctta tggtctaaat tagaaaaaga acgtgaggaa attatagctt tgctgacttc
     7741 tagtttagag acaacagatt ttaataagcc tttggattat cgttttatct ttggctatta
     7801 tgccgagaaa aaatattttt acaccccaaa agatgaaagt gaggacgcat agatgttaga
     7861 acacaagatt gattttatgg taactgtaga ggtcaaagag gcaaatgcta atggagatcc
     7921 actttcaggt aatatgccac gtacaaatgc taaggggtat ggattgatga gtgatgtctc
     7981 tatcaaacgt aaaattcgaa atcgtcttca agatatggga caatcaatct ttgtacaggc
     8041 taacgagcgg attgaagatg agttccgttc gcttgaaaac cggttttctg ctcaatttga
     8101 taagaatgat aaggatgatg acattgagcg aagagccaat gagctatggt tagatgtgcg
     8161 ttcctttggt caggtcttta cttatctgaa aaagtcgatt ggtgttcgtg gccctgtgtc
     8221 catcagcatg gctaaatcct tggagccagt tgtcatctca agccttcaaa tcacacgtag
     8281 taccaatggt atggagccta aaggggatag tagccgttca tctgatacaa tgggaactaa
     8341 gcactttgtt gattatggta tttatgtgat taaaggatca atcaatgccc attttgcaga
     8401 aaaaactggc tttagtgagg aagatgctga cattattaag caagctcttg tcagtctttt
     8461 tgaaaatgat gcgtcttcag cacgtcctga agggtcaatg cgagtgcgtg aggtcttttg
     8521 gtttacccat tctagcaaat taggcaatgt ctccagtgcg cgtgtctttg acttgttggt
     8581 gtttgatatg gaaacaccag ataaagatcg ctacgaggct tatggtattc atttagatga
     8641 ggaaaaatta gcagcctatc aagcaaaagg attaacggtt gaggtcctag aaggattgta
     8701 gaatggttta tgtagaagat gactacctga tgttatcagg tatccagcat tttcaatttt
     8761 gtaagcgtca gtgggcattg attcacattg accagcagtg ggtagataat gaagcaacgg
     8821 ctcatggtca gattctgcat acaagggctg ataatcctta tattagagaa aaacgaaagg
     8881 acttcttttt gtcgcgtgcg atgcatattt cttctgctcg tttgggcttg tatggggtta
     8941 tggacgtggt tgagttctat aaggatgatt caggtgtaac ggtgaaaggc aagcgcggaa
     9001 gatggttgcc tagagtggtt gaatacaagc gaggcaagcc caaaaaggat aggcgtgata
     9061 ttgtgcaatt agttgcccaa accatgtgct tggaggagac cttgaattgt caaatcgcag
     9121 aaggtagcct ttattatcat agtgtcaata agaaggtcca aatagctatc acagatgagt
     9181 tgcgaaggga ggttcaggag ctagccaatc agatgcatag gttctatggg gctaaggagc
     9241 ttcctaaggc agaatatttt aagaattgtc agctatgttc tttagtagag gtgtgtaagc
     9301 cgcgtatcag caagaaggtg cgaaatgttg atcgttatat agcagctgct atggttagtg
     9361 aggaaatcat atgaaaaagc ttttaaacac cctctacctg actcaggaag attattatat
     9421 caccaaagag ggagacaata ttgttatcaa acaagatggg aaaacggtat cgcggtttcc
     9481 gtttcgtatc attgatgggg tggtgtgttt ttcttacctg ggtgcttcgc ctgccttgat
     9541 taagctctgt acggagaatc agattaattt gtcctttcat acgcctcagg gccgtttttg
     9601 tggtcgttat gttggtgcga caaatggtaa tgtgctgttg cgacgagagc actatcgttt
     9661 agcagatcgc gatgagtcct tggagtatgc caagcggttt attttagcaa aaatatcaaa
     9721 tgctaggaaa tacttgcttc gctttaggcg tgaccatcga gatcagattg atggcaagct
     9781 ttttgaagag gtcaatggtg agctgatctg ggcacttgag atggtgcagg caacagataa
     9841 taaggattct cttcgcggca ttgaaggtca agctgccaac cagtacttcc gtattttcaa
     9901 tgatttggtg ttaacggata agaaggcctt tacctttggt ggtcgcagta agagacctcc
     9961 cttagatcgt gtgaatgccc ttttatcttt tggctacagt ttgctgacct ttgaatgtca
    10021 gtcggcctta gaggcggtcg gcttggatag ctatgttggc ttttttcata cggataggcc
    10081 gggtcgcgct agtcttgcct tggatttggt agaggaattt cgttcctata ttattgatcg
    10141 ttttgtgttt tcattgatta ataaaggaca gctgacaaag aagcattttg atgttaagga
    10201 gagtggcagt attttgctaa cagaaaaggg acgtgtgaca tttattgagc tgtggcaaaa
    10261 gcgtaagcac atggaggtag agcacccgtt tacaaaagaa aaggtcaagc taatgctcct
    10321 gccttatgtg caagcccagc tccttgctaa ggctattcga ggggatattg atagctaccc
    10381 accttttatg atttaggaga ttactgatga tggtattggt tacctatgat gtgaatacag
    10441 aaacagcatc agggcgaaaa cggctacgtc aggtagcaaa attgtgtgtt gattatggcc
    10501 agcgcgtgca gcattcggtc ttcgaatgct cggtaacacc tgctgaattt gttgagatca
    10561 agcataagct gacgacgatt attgatacag aagtggatag tattcgtttt tacttgttag
    10621 gaaagcactg gcaaaatcgt gtcgagacgc tagggcgttc tgatagctat gatcctgata
    10681 taggtgtcct acttctgtaa aaggagtgag tgcgagcctg agtcactcat aaaatgctag
    10741 gagactcgcg ctaaaataag ctaaaaaaat agagaaatga gaggttatag ctaaatatgt
    10801 tattggctag cctatgtcag ttctctataa actgtgctat gctgcgcagt ctcgccccat
    10861 acgggcgagt ggattgaaat aaaaaaattg agaatggcaa acaacccaca aatgtctcgc
    10921 cccatacggg cgagtggatt gaaatttgat ggggttggtt ttgttggggt gtaccaagtg
    10981 gtctcgcccc atacgggcga gtggattgaa atgtctttgc gctgtaactc tgatatttta
    11041 tctttgtctc gccccatacg ggcgagtgga ttgaaatact aatacagact tacaatctca
    11101 aagtccacta ggtctcgccc catacgggcg agtggattga aattgtaatt cgacgagacc
    11161 aggcacccga agtttatagt ctcgccccat acgggcgagt ggattgaaat ttttttagca
    11221 gctttacaat aaagacatga ctttgtctcg ccccatacgg gcgagtggat tgaaatcagt
    11281 gatagtcttg gcggccgagg accattgcag tctcgcccca tacgggcgag tggattgaaa
    11341 tcatattttt cacctttttt aaaatccaca ctcggtctcg ccccatacgg gcgagtggat
    11401 tgaaataaaa attattaggc acaaaagaca ttacccaatg tctcgcccca tacgggcgag
    11461 tggattgaaa ttgctgaccc aagccaagtg ggacataata ctgggtctcg ccccatacgg
    11521 gcgagtggat tgaaattgat gagcgtgtat cttcgtttgc aacaccatct tgtctcgccc
    11581 catacgggcg agtggattga aataaaaaat caactagcca ctggtttcct ttacgaacgt
    11641 ctcgccccat acgggcgagt ggattgaaat atctttgtga tcagtcacta gtaagatcgt
    11701 taagtctcgc cctatacggg cgagtggatt gaaatcaatt tatcaagaga gcgctagact
    11761 agttactcgt ctcgccccat acgggcgagt ggattgaaat tggatttaac aagcacgaac
    11821 gggtgcacaa tctcgtctcg ccccatacgg gcgagtggat tgaaatcaca tatagcggaa
    11881 caatcggacg ctatcatgga ggtctcgccc catacgggcg agtggattga aatccttgcg
    11941 ggagcttctt tggcctcgtt aaacactcgg tctcgcccca tacgggcgag tggattgaaa
    12001 tatttagcaa tcctccgtta tttgcctaac ttaagtctcg ccccatacgg gcgagtggat
    12061 tgaaatttgc tagttatgga aaaggttatg aaaaagattg tctcgcccca tacgggcgag
    12121 tggattgaaa tcatatctcc ttgggttatc tgtgccatca aggttaggtc tcgccctttg
    12181 cgggcgagtg gattgaaatc atatctcctt gggttatctg tgccatcaag gttaggtctc
    12241 gccctttgcg ggcgagtgga ttgaaatttt ggcatgcctc acatcagact catgtctagc
    12301 atgtctcgcc ctttgcgggc gagtggattg aaattttgct gctatgcaag gagtgacact
    12361 gattgaagtc gctctcttct cgagggcgtg gtccgtatcc ctggtacttt tcatgaaggg
    12421 ataaatcata tcacattaat caagttgatt taagtttttt atggtactat gtcaaataga
    12481 taaaaatctc tgtgtcaagt gtagtgggtg actgataact aagcacgaga ggagacgaag
    12541 gtcgtcttct cttttatgat gttcaaagca aggtaaatac ttttcttgaa gttgtcaacg
    12601 tttctgaatc caaaagcatt gcgcttgata cctttgataa atttgttagt tgcttcaagc
    12661 ttggcgttag aataaggcag ttcaatggca ttgatgatat agtcgttata gcgtataaag
    12721 gtgtttaaag tcgttttgaa ggtgtgattg agatgaggca aagcatcttg acttaaccca
    12781 aagaagagct ctgtcttctt ttcttgcaag tgaaaaagaa gtcattggta cagatcataa
    12841 tagcctttta actcagggat tcgtttgaaa atcttattga gacattgtct aggagttaat
    12901 gtttctctaa aggtcctaga gtagaaagta ttaagagata gtttccagtt atcctttaga
    12961 ctaagcttcc aatagtattt aagagcccga tattcaagag ctttcttatc aaatggcttc
    13021 atgagttgaa tgcgagtttg attgagcgct ctactcatgt gctacacaat gtggaagcga
    13081 tcgagaacaa ttttagcttt tgggagtgaa ctagtccagt ggactaattc agcctgagct
    13141 taaaaataga agagcgaagg gtttaatgag aggaatgtaa cttcctgaca tatcgacagt
    13201 aacaactttg cccttatttc tagcttcttt ggagtactta aagaagtgat ttcgaatggt
    13261 tgtttgacat ctgttattgc gaatgataat gattttcttg gtgttgaaat cctgagcgat
    13321 aaaggctagt ttgccctttt gataagagaa ttcgttccag gaaagcacct caggtaaggt
    13381 ggtgtaatcc tctttaaagt gacattgctt gagcttatga tagacggtag aggtagagat
    13441 agcgagttta gcagcaatat gcgtaaaagc ttctttattg agcaatagct gagagatctt
    13501 ctgtctaact ggttcagaga tttggcaatt tttcttcacg agattggttt cagagacagc
    13561 taccttccga caggtttgac attgaaacct gctctttttc aatcgaataa ggctagggaa
    13621 gccaccgatt tcgatgaaag ggattttaga gggcttctgg aagtcatact taatctgagc
    13681 tctcttacag tgcttacact taggaggttg atagtccaat gtagcgatga cttcgatatg
    13741 tgtatcatgc tggatagcct tatcgaaggt gatattttga tctttaattc cgatgagtag
    13801 tgtggtatga tgaatctgtt ccataagaca ctttttaatg atggtctggt cgcttttcat
    13861 gataagcctt atgggacttt ttgtgtactc aaaagcccta taatctccat agtggactta
    13921 cccactacag aaattattaa gccctaaaaa ccaatctgag gttgttgcaa caggattggt
    13981 tttttcttgt gattgcagat cagacttttc aaaagaacaa gcacattatc tcagctagac
    14041 tggtgcttga tagctcctga gcccttgttt gctgtagctg ataggacttt gctgatggcc
    14101 tagtcaggca tatcgtatca aattcaagtt ttttcatgtc actgtctata gtttgtctgc
    14161 cctactttag gtagaataga ggtaacttaa gagaggagtt tattatggaa ttaacgatgc
    14221 ttttgatggt ttcagttttc attgcagggc tgttatcatt cttttcccct tgtatctttc
    14281 cagttctgcc ggtgtattta ggcattttgt tagattctga tgattctagg tctattacta
    14341 tttttggcaa gaaactatat tggtacggta ttgttaaaac ccttgctttt atttcaggtc
    14401 tatctaccat ttttgtcatt ttaggctatg gtgctgggtt actaggtaat attttatatg
    14461 ctgcttggtt tcgctatctg cttggtgcct ttgtgatttt gttaggtatt catcaaatgg
    14521 aaatcgtaac cattaagaag ctgcaatttc aaaagagcgt agcatttcaa aataagaagg
    14581 accgcaatgc tgttttaaat gcctttttgc tgggaattac ctttagcttt ggttggacgc
    14641 cctgtgttgg accagttctt agctcggtgc ttgccttagc ggcttcaggt ggtagtgggg
    14701 cttggcaggg tggcttcttg atgattattt ataccttggg cttaggccta ccatttttac
    14761 tgctatcttt tgcttctggt attgtgttga agcactttaa taaattaaaa ccacacattc
    14821 ctctattgaa gaagttaggt ggattactta ttgttgtaat gggcttactg ttgatgacag
    14881 gaaatctcaa tagcttatca ggtttatttg aataaaggag aagaaacaat gaaaaaaaca
    14941 acatttttaa caacaggctt agcatgtctt gctttattaa ctgcatgttc gtcgaaggat
    15001 aaaatggcca tgaatgataa taaaaaagac catatgacca tgaccgatga caaatcaaag
    15061 atgaaaaagg atcaaaaaga catgatgtca gacaagaagg atatgatgtc agatgacaag
    15121 cacatgtcag atgctgacaa ggctagcaag aatgatgggc aaatggctcc agattttgaa
    15181 ttaaagagca ttgatggcaa gacttatcgt ttgtcagatt ttaaaggtaa gaaggtttac
    15241 ttgaaatttt gggcctcatg gtgttctatc tgcttatcaa ccttaggtga tacacagtca
    15301 ttagctacga tgaaggataa ggattttgag gtcttaacca ttgtttcacc tggtcatcaa
    15361 ggtgaaaaat ccgaggctga tttcaaaaaa tggtttgaag gaacagactt taaggattta
    15421 ccagtcttgc tcgatccaga tggcaagctg ctagaggctt atggtgtgag atcttatcca
    15481 actgaaattt ttgttggcag tgatggcatt ttagctaaga agcatattgg ttatgcaaag
    15541 aaatcagaga ttgaaaaaac cttaaaggag attaaataag caaaggaggc tgtctcatgg
    15601 aacacaaatg gaagttattg ctactcgttt ttggagcctt agtattttta ggaggtgttt
    15661 tgatggtctt tcaaagaggc tacgctacta gctaccataa taatcaggtc aagctgcctg
    15721 ccaaagggac gtctcagctc aagaagactg ctaatgccaa gctgcctgag aagaaaaagg
    15781 agatttacct tgcaggaggc tgtttctggg gtgtggagga gtatttttca aatgttgatg
    15841 gtgttctaga tgctgtttct ggctatgcta atggtagagg cgacacaacc tcttatcaat
    15901 tgctgcacca gacagggcat gctgagacgg ttaaggttgt gtatgatgct aatcggatta
    15961 gcttaaagga gcttctttta cactacttta gaatcattga cccaacaagc cttaataagc
    16021 agggcaatga tcgtggcagc cagtaccgca caggcgttta ttatacggat ccatctgatt
    16081 tgactactat tgatatggtc tttcaggaaa cagcttcgga ttacaaaaag aaaattgttg
    16141 tggaaaaagc tcccctaaag agctttacca aggctgagga atatcatcag gattacctca
    16201 agaaaaatcc taatggctac tgccatatta atgtcaacga ggcttcttac ccagtgattg
    16261 ataagacaaa ataccctaag ccaagtaagg aagagattaa aaagaagcta tcaaaggatg
    16321 aatatcgtgt gacccaaaac aatgaaactg aaaaagcctt ttcaaacagg tactgggatt
    16381 cctttgaagc agggatttat gtagatgtgg tcactggtga gccgctgttt tcttccaagg
    16441 ataaatttga atcaggctgt ggctggccaa gctttagcag gcctattagc ccagatgtgc
    16501 tacgctataa gacagataag agcttcaata tgaaccgcac agaggtgaga agccgctcag
    16561 gcaattccca tttaggtcat gtctttaccg atggtcctaa ggatcagggt ggtctgcgtt
    16621 attgtattaa cagtttatcc attcgattta ttccaaaggc tgaaatggaa gctaaaggct
    16681 atggttacct tttaacagca gttgattaga agattatcct aagatttgtt ataataagat
    16741 gaggaagcac agatggttga ttatagttat taagacctga agattacttc agtcgatatt
    16801 gctaaatgtg atcaggctca tgccctttag tcttgcttaa gaggtagtag cttttaaaag
    16861 agtgattacg ataagaggca tttgctcaga gcttgtccta tttagttctt gtcgagctat
    16921 gtgcagagct tgtatgacta tggtcactaa gcattagaaa tagtaggaga aatggtgtgt
    16981 actcattact tattgttgaa gacgaatacc ttgtgcgtca gggtattcgt tctttggttg
    17041 attttgacca atttgccatc gatcgtatag cagaggctga gaatggtcag gtggcctggg
    17101 agttgttcca agaaaatcct tatgacattg ttttaacaga tattaatatg ccaaagctta
    17161 acggcattca actggcagag cttataaagg caagggctcc aaagactcat cttgtttttt
    17221 tgacaggtta tgatgatttc aattatgccc tatctgcctt aaagctaggg gctgatgact
    17281 acctgctaaa gccattttcc aaatcagatg ttgaagaaat gctcaaaaag ctaaagcaga
    17341 aattagaaaa gctcaaaaaa acagaggccc ttcaaaaact agttgataag ccgcagcaag
    17401 aaggctcaga aattaagcta gctatccaag agcgtttagc tgattcaagc ctaacgctaa
    17461 agagcctatc aagccagtta ggctttagcc ctaactatct aagtgtttta atcaaaaagg
    17521 atctaggttt gccttttcag gattacttga ttcaggagcg tctcaaaaag gctaagctct
    17581 tattattaac aacggatttg aaggtttatg agatagcaga gcaggttggc tttgaggata
    17641 ttaattattt ttcccagcgc tttaagcagt tggttggaat gacaccaagg caatataaaa
    17701 aaggagaagg ccaatgaagc gctaccctct tttagtacaa ttagtgagtt atttttttct
    17761 gattgtgatt tcactaatca ctattctggg agtgatttat tatcagacca gctctcataa
    17821 tatcaggcag ctcattgaac gcgaaaccag acagagcatt cggcagagct ctcaatttat
    17881 tgatgcctac attaagccat taaaggagac aacctcagct ttagctagcc atgctgagat
    17941 tcagagcttt gctaaggcag ctaacagtag tcatcaagag caggtgttgg cactgatgac
    18001 aactgtgctg tcgaccaatt cagaccagct ctcagcggtt ctggtgacaa aggatggtcg
    18061 tatggtcaca accaacccaa agctaatcat gactacctcg catgatatga tggcagagcc
    18121 ctggtacaag tcagctattg accgcaaggc catgccggtg ttgacccctg caaggcagct
    18181 gtcctcgcat tctaaaaagg attgggtggt ttcagttact caggaggtag ttgatgagac
    18241 agggaacaat ttaggggtgc tgcgattgga tattggctac aataccatca aatcctccct
    18301 agatcaattg cagcttgggc gtaagggctt tgcttttatt gttaatgata agcatgaatt
    18361 tgtctatcac cctaaaaata ctgtttatag ctcagcaaag gaaatggcag cgatgaagcc
    18421 ctatctggcg gtcactgatg gctatacaag gcctaaggat tattttgttt accagagggt
    18481 gattccagac agtcaatgga cactggtcgg agttgcctct ttagatcagc tctatcatgt
    18541 gcaaaggcag attttttggt cctttttagg gacagggctg cttgcaactg tcatctgtgg
    18601 tcttgggaca gtatttgttc tgagaagctg gattggtcct atcaggaggc ttcaggctct
    18661 cattttagct attcaaaagg gtaaccgtca gctgcgtgct gaggaaattg gctcgcctga
    18721 gttagctgat ttggcacgtc agtttaacgc catgctggat caaattgata gcctcatggt
    18781 atcagtggcc gacaaagaaa aagccattgg gcagtatcgt ctgcaagcct tagccagtca
    18841 aattaatcct cattttttgt acaacacctt agatactatt atttggatgg cagagtttaa
    18901 tgacagtcag cgtgtggttg atgtcaccaa gtctctggct aagtatttcc gcttggcctt
    18961 aaatcaggga aatgaattga ttagccttgc tgatgaattg gatcacgctc gtcagtattt
    19021 gtttatccaa aagcagcgct atggagacaa gctgcactat gagatcaagg ggcttgagaa
    19081 gtaccaagac tttatgattc ctaagctgat tcttcagccc ttagttgaaa acgccattta
    19141 tcatggtatt aaggaggttg atagacctgg aatgatcaga gtgactgtat cagaagctga
    19201 tcgtcatgtg atattatccg tttgggataa tggaaagggc ataagcttag ctgatgacag
    19261 cagtcaggcc ctgcttgagc gtggcggtgt tggtttaaaa aatgttgacc agcgcttgaa
    19321 attacagtat ggtcatctct atagaatggc aatcactagc gagcaggctg tttttactga
    19381 gattaagctt tatcttccca agccgcttga tggcctaaat gagctcccct aatcaatccg
    19441 cccttagtag aacaaggaaa agagaggttt atgtctttag aatccgatta ttttaagcga
    19501 aaaagtcctg tatttgaggc tcttatccct tatggcttta cccaagaggg tgacacttat
    19561 tgttatcagg agtcatttat ggaaggagat ttcaaggcct tgattacgat caagtcgtct
    19621 ggtcagctct cagctagagt gattgatact gaccttgggg aggactatct ccccttgaga
    19681 aatgatagac agcagggagt ttatgttggt caggttcgtc aagcttatct agagcttctt
    19741 ggacgtttat cagctgcctg ctttaggtct accccttttc agacaaggca ggccaaccaa
    19801 gtggcaacaa gcattagcca gcagtggaat gatccactag attacccctt tgaaaaattc
    19861 cctaatattg ccacttatcg tgtttctggc aagtggtatg cgatggtatt gcccctgcta
    19921 gccgataaat taggacaggt gccaaaggtc ttacaggggc aaatggttga ggtattgact
    19981 gttagaattg ctcctaatca gctaacacac ctcttgcagc aacgtggtgt ttacccagcc
    20041 tatcatatgt ctaaaaagac ctggattagc ctattactag atggtacact agcagatgat
    20101 cagctctggg agctagtcac gaaaagtcgt caattggcta atcctaatgg cctagctaac
    20161 ccagatggac cagattactg ggtgattcct gctaatctca gctattacga tattgacgcg
    20221 gaatttgcag ctaatcctga cattctctgg acgcaaaagg cttccataaa agctggagac
    20281 tatgttttta tttatatcac tgcaccgacc agatcgattc gctatgcctg tcaggtcttg
    20341 agatcagaca ttcctaatca aggctatcgg aaaaatgcga agattaagac cttaatgtcg
    20401 ctacgcttgt tgcattgcta cgaagatggt ttgatttccc ttgatttgat gaaacagtat
    20461 ggggttaatg ctgttcgcgg tccaagacgg ttaagcccac aattagttgc atttttgaag
    20521 gaaaaagagt attttaaaga tgtgaaacaa aaagaatgat aaggagagtg ggtatgactc
    20581 aatttatagc agatcagagc ttttgggaat tatttcctga tgctaagcta ggtgttttgt
    20641 tgctcaggaa ctatgacaat caggaagact ccccacaaga ggtcaagcaa ttattggcag
    20701 acagccatga catagctaag cagtatttga ctgaagagtc gtttagtgac aatgagatca
    20761 ttcaggtcta tcgtcaagcc tatcagcgtt ttaagacaaa aaagggagcc agatccagta
    20821 ttgaagctct cctaaagagg gtggcaaatg gtcaagtcct gtcctccatt aaccctctgg
    20881 tggatattta caatgcagcc agtctacggt ttggtctgcc agttggcgca gaagatagtg
    20941 attgctttgt aggtgactta cgcctgacgt taacagaggg aggcgatgag ttttacctca
    21001 ttggtgattc taaaaacagt ccaactctgc caaatgagct ctgctacaag gacgatgctg
    21061 gtgctgtttg ccgttgccta aactggcgcg atggtgaaag gacaatgatt accgatcgca
    21121 ctaaaaatgc ctttttagtc attgaagcat tagatagcaa gacccaagca agactacagg
    21181 acgcccttaa gtttatcgaa gacaaggcta agtgctacct gaaggcagaa acagcactat
    21241 atacgctgga tcaagcctca ccaagtatca cgttttaatc aaaaaaagct aggaagccag
    21301 tattcctagt tttttcagtt gttcaggtgc ttttatttgg tgttgttggg gggagatttc
    21361 cttatgctgc aggatatggt atgacaggga aacagttttt gcttgtttga tttaataaag
    21421 cgattaataa aagcttttaa gctgttgttc atgctaaagg gctttcttaa tcctatcaga
    21481 gaactttaaa aaatagtata atgtagttaa cttgtgagga taactaagga ggtcagcatg
    21541 gagttatttg acaaggttga tgatacgtta aaggctttag cgattgacta ccagctggtt
    21601 gagcatgagc cagctttaac cacagagcag gcagaccagt tcatagaggg cattgaaggg
    21661 gttagaacca agacaatgtt tttaacgacc aggaaaaaga accattttta tctggtcatt
    21721 atggatgata ctaagagact ggatatgaat cgcttcaagg aacttgttgg agaaaagcag
    21781 attaaaatgg catcagcaga atgcttgctt gccaagatgc agctgccacc aggagttgtt
    21841 tctccttttg gtctcttaaa caatgaggat aaggatattc aggtttatgt tgataaagcc
    21901 attgctcacg aagctagaat gagctttcac ccaaatacga atgacaaaac catctttatt
    21961 caaacagatg acctctttaa gtttctagcg gctataggtt acgcggtcaa tatcgtggat
    22021 ctatagctaa attcaaggtt cttctagcgg ttcttgctca catcagttca caaagctagt
    22081 ggcctagcca atccagggta aacaaaaagc acaatagcct ttcttgacta ctgagaatag
    22141 ccagtagacc cttgtgtcat atgcttatct ggtatttgag cttaaatctc aaggcttttg
    22201 aacagaggat caaacaaaga aaacgaccag cagaccttgc gtgatgactg attatcaagt
    22261 ctggtaggag ctaaaattag tcatggtctt gaggcctaaa acgtcccatt tgtcgcccct
    22321 gttgctgggg cattagttga tatgtatacc cacgactaac taattcgaga agggctgtcg
    22381 ctctctttgc aggagcgtgg gttaaattgc aaaagggacc tgatagacat ttctgctttt
    22441 aaagctagtc catcaaaaaa aggcatgaca ccactgtgat gggatatcat gcctttttgc
    22501 taagctaaag tgatttgtcg cttcctttga aagggttatt tattgctaaa gaagaagggt
    22561 ggtgtgtaat ggctcaggat ttcaaagcaa gctttggcct gctcattgtc ctcacagata
    22621 atcagacagg tatcatcacc acagatagtg gctacgattt ctgagatttg catagcatca
    22681 aggatagagc caaaggattg tgccagccct ggtaaggttt ttaaaataat ctgatgctga
    22741 acaaccctga gcatgacaag ggcgtcctcc atataaaagc gcaaacgatg ctcccaacgc
    22801 gtctgagaaa tggccagcgc ttcataatgc gtgtcattac cagttgtaac cttaacaagg
    22861 tttagctctt tcatatcgcg tgataaggtt gcctgtgtga tgcttatccc attttttcgt
    22921 aagcgttcct gtaattcctg ctgtgtgtga atagttgttt cagaaattag agatcgaatt
    22981 aattgatgac gtgtttcttt tttattcatt tcttataata ttcccctaat gattggtaac
    23041 attcagagta taacaaaaag atggcagtgt gtaaagtttt agatgaaccg cttacaaaaa
    23101 tagccttttt atgttaaaat aaaacaggtg cttagaaaag gagatttgcg tgattcgaag
    23161 agaagattat caatacctta gaaaacttga tgatttctgt catttttcaa ttgaacaatt
    23221 tgacaagatt gtcggccaaa tggaatttag acaagctaaa aaggatcata tgttattttt
    23281 tgaaggtgat aagagggaca gactcttttt agtgacctca ggttatttta agattgagca
    23341 gtcagatcga acaggaacct ttacctatac tgatttcata cgacatggga caatttttcc
    23401 ctacgggggt ctgtttacag atgactacta tcatttttcg gtggttgcga tgacagatgt
    23461 cacttacttt tatttcccga ctgatttgtt tgaggactat tccttgcaca atcagcagca
    23521 gatgaagcat ctctacagta aaatgtcgtc cttgctggag cttcatgagc tcaaggtgcg
    23581 caatctcatc acctccagtg caagctcacg tgtgattcaa tccttggcta ttttactggt
    23641 tgaaatggga aaggatagcg ataccctgcc ttttcagctg acgactactg acattgcaca
    23701 aatgagtgga acaaccagag aaaccgttag ccatgtcttt agagatttga aaaaggaagg
    23761 cttgattgca gtcaagggga aatacctcac ctacctagat aaaagctatt ttctgcagta
    23821 tacaacctaa ggtcaagtca aaaggcttcg cttaaaaagt tttttgactt ttttcaattt
    23881 ataaatataa gatttttcgt taaaatgtaa aaaaacaaac aagaaaacgt atacaaaaac
    23941 ataaacattc atttttgagc aagaaagtgt aatcgtttac acaaatcagc tatgagaaat
    24001 accctatttt tgaatgccgc ttggagtaaa ctaggggtgt aagcaaaagc taagagtctt
    24061 agcagtgaat tcacaaaaca ttagaaagag gtaattctta tgactgctca aacaccgatt
    24121 catgtttact ctgaaattgg caagctaaaa aaagttttgc tccataggcc tggcaaggaa
    24181 attgaaaacc tgatgccaga ctacttggaa cgtctattat ttgatgatat tccatttttg
    24241 gaggacgctc aaaaagagca tgatgctttt gcacaggcct tgagagatga aggcgtagag
    24301 gtgctatacc ttgaaacact ggctgcagag tcacttgtga caccagaaat tcgtgaagcc
    24361 ttcattgatg aatacctaag cgaagctaat attcgtggaa gggcaactaa aaaagctatt
    24421 cgtgagttgc tgatgtctat tgaagacaat caggaattga ttgaaaaaac aatggcaggt
    24481 gtgcaaaaat cagaattgcc tgagattcca gcagcagaaa aaggcttgac tgacttggtt
    24541 gaatcaagct atccttttgc gattgaccca atgccaaacc tttatttcac acgtgatccc
    24601 tttgcaacta ttggtacagg tgtttcgctt aaccacatgt tctcagaaac acgtaatcgt
    24661 gaaacaatct atggtaagta cattttcaca catcacccaa tctacggtgg cggcaaggta
    24721 cctatggttt atgaccgtaa tgaaaccact cgtatcgagg gtggagatga gctggttctt
    24781 tcaaaagatg tgcttgcagt aggtatctca cagcggacag acgcagcatc aattgaaaag
    24841 ctcttggtta acatctttaa acaaaatctt ggcttcaaga aggttttggc ctttgaattt
    24901 gctaacaatc gtaaattcat gcacctagat accgtcttta caatggtgga ttatgataag
    24961 ttcacgattc acccagaaat cgaaggagat cttcgcgttt actcagtgac ctatgaaaat
    25021 gaagcgcttc gtattgtaga agaaactggt gatttggctg agcttttagc tgctaatctg
    25081 ggagttgagc gtgttgagct tattcgctgt ggtggtgata accttgtggc agctggtcgt
    25141 gagcaatgga acgacggttc aaatacgcta acaatcgcac caggtgtcgt ggttgtttat
    25201 aaccgtaaca ctattacgaa tgccattctt gaatcaaagg gcttgaagct cattaagatt
    25261 catggaagtg aattggttcg cggtcgtggt ggacctcgtt gcatgtcaat gccgtttgaa
    25321 cgtgaagaca tctaggagag gcaaatgaca agggttattg ttggaaatca gccttttcaa
    25381 cgggcagcta gcttatatat tcgctatcag gtttttgtct tagagcggca gattgatcgg
    25441 caagatgaat ttgattgctt tgacgataac gatcgcgtgt atgcagtctt gtatgatggt
    25501 gatcagcctg tatccacagc tcgcttttta cccacagcta aagatcaggc tcgtctaaca
    25561 agagttgcta cgctgcgtca gtatcgtggt aggggctatg gtgcgcaggt gatagaagcg
    25621 cttgagcagt atgccagaga gcaagcttac gagcgattgg ttattcatag cgagctaagt
    25681 gctcaatcat tttatgaagg gattggctat caggcctttg gcgagcctta tgatgaagac
    25741 ggtgagcctt gtcaatcagt agaaaaatat ttataaaaag gagaatttaa atgacacaag
    25801 tatttcaagg acgtagcttc ttagcagaaa aagactttac acgtgaggaa tttgaatacc
    25861 tcattgattt tgcagcacac ttgaaagacc ttaaaaagcg tggtattcca catcactatt
    25921 tagaaggtaa aaatattgcc ctcttgtttg aaaaaacatc aacgcgcaca cgtgctgcct
    25981 ttacaactgc ggcgattgat ttaggagctc atcctgaata ccttggcgct aacgatattc
    26041 agcttggtaa aaaggaatca acagaggaca cagctaaggt attgggtcgt atgtttgatg
    26101 ggattgaatt ccgtggcttt agccaacgta tggttgaaga attggcagaa ttctcaggtg
    26161 ttccagtgtg gaatggcttg actgatgaat ggcacccaac ccaaatgctt gcggactacc
    26221 ttactgtcaa ggaaaacttt ggtaagcttg aaggcttgac cttggtttac tgtggtgatg
    26281 gacgcaacaa cgttgccaat tcactgttag tagcaggtac cttactaggt gtgaatgttc
    26341 atatcttctc accaaaagag ctcttcccag cagaagacat cgtgaagctg gctgagggct
    26401 atgctaaagc atcaggtgcg catgtgttag ttactgacaa tgctgatgag gctgttaagg
    26461 gcgcagatgt gctttacact gatgtgtggg tgtcaatggg tgaagaagac aagtttgaag
    26521 agcgtgtgaa gctcttgaag ccatatcaag tgaacatgga gcttgttaaa aaagcagaca
    26581 acgacaacct tatcttctta cattgcttgc cagcctttca tgacacaaat actgtttacg
    26641 gaaaagatgt tgctgagaag tttggtgtag aagaaatgga agtaacagat gaggtcttcc
    26701 gcagcaaata cgctcgccac tttgatcaag cagaaaaccg tatgcacact attaaagcgg
    26761 ttatggccgc aactcttggt aatcttttca ttccaaaagt gtaagctgtg attggtacct
    26821 tttaatttat tttagctcat ttcattaatt taacaattta actactaaaa aacgtacttt
    26881 aactacatga cgagtcgttc tggttctcgt gtccttgacc ggaactggga cggcttattt
    26941 ttatgaaaag gtaagaggta atcactatga cagaagaaaa aaaacgaggt tttaaaattc
    27001 cttcttctta cactgttttg tttatcatca ttgctattat ggcagtatta acctggttta
    27061 ttccagctgg tgcttatgag actgctaagg atggcggtgt gatttcaggg acctaccaaa
    27121 cggttaagtc aaaccctcag ggcttttttg acattttaat ggcacctgtt cgaggcatgc
    27181 taggtgtcaa agggactgaa ggggcaattc aggtttcttt ctttattttg atggttggtg
    27241 gctttttagg ggttgtcaac aagacaggtg cgcttgatac agggattgct tctgttgtcc
    27301 gtaaaaacaa gggcagagaa aaattcttga ttgcaatttt gattcctttg tttgcacttg
    27361 gtggcacaac ctacggaatg ggagaagaaa caatggcgtt ttaccctctt cttattccgg
    27421 taatgattgc ggttggcttt gatagcattg ttgcagtagc tattatcctg attggttcgc
    27481 agattggctg tttggcttca accatcaatc cctttgctac tggagtggca gcagatgcag
    27541 ctggtgttag tatcgcagat ggtatgattt ggcggattat ccaatgggtt gtccttgttg
    27601 gtatgtctat ctggtttgtt tacagttacg ctagcaagat tgaaaaagac ccaagcaagt
    27661 ccttggttgc tgacaaagct gaagaacata aggaattctt ccagctacaa aattccggcg
    27721 aggatttgac tagtcgtcaa cgaaaggttt tagctatctt taccttgaca tttgtcatca
    27781 tgattcttag cttgattcct tgggaagatt ttggcattaa gctgtttaca aatatcaata
    27841 cttggctaac aacaacacct gttttaggtg gtattattgg taaaacaatg ggagcctttg
    27901 gaacctggta tttcccagaa attaccatgc tctttatcat gatgggtgtt ttagtggcta
    27961 ttgtttatcg catgtctgag gacgatttct tctcagcctt tctaagtggt gcaggtgaat
    28021 tccttggtgt tgcgattatt tgtgcggtag cgcgtggtat ccaggtgatt atgaacggtg
    28081 gtatgattac tgcgaccatt cttcattggg gtgagacagg gctagcaggc ttgtcatcac
    28141 aggtctttgt tatcttagct tatattttct atttaccaat gtccttcttg attccatcaa
    28201 cctcagggct tgctggtgca actatgggaa tcatggcacc gcttggacaa ttctcaaatg
    28261 ttcctgctca cttggttatc acagccttcc aatcagcatc aggtatctta aacatgattt
    28321 caccaacctc tgctattgtt atgggggcgc ttgcgcttgg acgtattgat ctaagtactt
    28381 ggtggaaatt tatcggcaag tttatcgtta tggtaatgct tgttagtgtt ctgctattag
    28441 tagtagcgac attcttttaa gagataggag gcttctatgg aaacctatat ccaatcaaga
    28501 caccaagagg cttgtgtggc tgcgattaaa aaaatagtgt cttacccttc tgtgctgaat
    28561 gagggggaaa atggcacacc ctttggtcaa gctattcaag atgttcttga agcaacctta
    28621 gccttatgcc aagaccttgg ttttaaaacc tatattgatc ctaaaggcta ttatggctat
    28681 gctgaattag gtgatcaaac agaggtgctt gctattcttt gccacttaga tgtggtgcct
    28741 gctggtgatt tgaagctatg gcatacagat ccctttactt gtattgaaaa agatggctgc
    28801 ttgtacggac gtggcactca agatgacaag gggccttcga tgatggcact ctttgccact
    28861 aaagcactca tggacgctgg tgtggtcttt aacaaacgca ttcgctttat ctttggaaca
    28921 gacgaagaaa ccctctggcg ctgtatgaac cgttataatg aagtagaaga ggaggcaacc
    28981 tttggttttg ccccagactc aagctttcca ttgacctatg ctgaaaaagg gcttttacaa
    29041 gccaagctag ttggtaaggg gtcggctaga ctcaatcttg aggttggtca ggcctataat
    29101 gtcgttccag ccagagcttc ttatcaggga gacaagctag aggcattagg tgaagagctt
    29161 gataggcttg gctttgaata tgttgtcaaa gacggtgagc taaccgtcta tggacttgct
    29221 cagcatgcca aggacgctcc agatgggatt aatgccctta tcaggcttgc aaaggctctt
    29281 gtagtgcttg agccagagcc agtccttgac tttcttgctc atgtggttga cgaagatggc
    29341 agagcagtca atatttttgg tccagttcag gacgagccat caggggggct tagcttcaac
    29401 gtagctggtc ttaccttaac aaaagaggtg acagaggttc gcttggacat tcggattccg
    29461 gtcttagcag ataaagatac cttagtagac cagttaagtc aaaaagcgca ggactatggt
    29521 ctagcttacg aggaatttga ttacttggca cctttatatg tgcccttgga cagcgagcta
    29581 gtgactactc tgttagaggt atatcgtgaa aaaacagggg atcaatcacc agcccaatca
    29641 tcaggtggag caacctttgc tcgtacaatg gctaattgtg tggcctttgg agcattattc
    29701 cctgatgctg ttcaaacaga acaccaagaa aatgaacgta tcgtcttagc ggatgcctac
    29761 cgttcaatgg atatctacgc ggaagccatc taccgactaa cacgataaga tgaggagtat
    29821 catatatgac aaaacaaaaa attgttgtcg cacttggagg aaatgcaatc ctctcaacag
    29881 acgcgtcagc taaggcacaa caagaggcct tggtttcgac atcaaaatca ctagtgaagt
    29941 taatcaaaga aggccatgag gtgattatca cgcatggcaa tggtccgcag gttggtaatc
    30001 tcttattgca gcaggcagca gctgattctg agaaaaatcc agctatgcca ttagatacct
    30061 gcgttgctat gacagaaggt agcattggtt tttggctagt caacgcgcta gacaatgagc
    30121 tacaagccca aggcatcaca aaagaagtag cagcagttgt cactcaggtc attgttgatg
    30181 aaaatgaccc tgcctttaaa aacccgacta aaccaattgg tccttttttg accgaagaag
    30241 acgctaaaaa gcaaatggca gaatcaggtg ctagcttcaa ggaggacgct ggtcgtggct
    30301 ggcgtaaggt ggtgccatca ccaaagccaa ttggtatcaa agaagctaat gtgattagaa
    30361 gcttagttga ttctggtgtt gtggtggtca gtgctggtgg tggcggtgtg ccagttgtta
    30421 aagaccctgc aagtaaaacg cttaccggtg tggaagctgt tattgataaa gactttgcta
    30481 gccaaaccct ttcagaattg gttgacgctg atctctttat tgtcttgaca ggtgttgata
    30541 atgtctatgt taactttaac aagcctgatc aaagaaaatt ggaagaggta acggtttctc
    30601 aaatgaagga atacatcgct caggaccaat ttgctcccgg aagcatgctg cctaaggtgg
    30661 aggctgcaat tgcttttgtg gaaaacaaac caaatgccaa agctatcatc acatcgttag
    30721 aaaatattga caatgttctc tcagcaaatg ctggtacaca aatcgtcgca ggctaattca
    30781 gatgactgcg caatgagctt aggcttttgt gctttgatag gttttagctg attagcttga
    30841 aaaattgatt taaaaggtta aattaggtta atttagcctt ttcttttact tttaatcggt
    30901 gtataataag cgtaatattt ttttattttt actcatgatt agaatggtaa aaaataaagg
    30961 tgacttagtc gcgaaaatga tttaaaggag gagctatgaa aaaaagcttt attcatcaac
    31021 aagaggaaat ttcctttgtt aaaaatacat ttacgcagta tttgattgct aagcttgatg
    31081 ttgttgaggt gcagggtcct attttaagta gggtcggaga cggcatgcag gacaatttat
    31141 ctggggttga aaatccggta tctgtccatg tcttgaacat tcctaatgca acctttgagg
    31201 tggtgcattc gttagcaaaa tggaagcgtc ataccttagc acgttttggc tttaatgaag
    31261 gtgaaggtct tgtggtgaat atgaaagcgc tccgtcctga tgaagattcg ctagaccaga
    31321 cgcattcagt gtatgtggac cagtgggatt gggagaaggt tatccctgat ggccagcgta
    31381 acctagctta cctcaaagag actgtcgaaa cgatttataa ggtcattcgc ttgacagagc
    31441 tagctgttga ggcacgctat gatattgaag ctgtcttgcc aaagaaaatt accttcattc
    31501 acaccgagga gcttgttgcc agataccctg atttgacacc aaaggagcgt gaaaatgcta
    31561 tcacaaaaga gtttggtgcg gtatttttaa ttggtattgg cggtgtattg ccagatggca
    31621 agccacatga tggtcgtgcg ccagactatg atgactggac cagtgagtca gaaaatggct
    31681 accatggctt aaatggtgat attctcgttt ggaatgagca gctaggcaca gcctttgagc
    31741 tatcctcaat gggaattcgt gttgatgaag aggctctaaa gcgtcaggtg gacattactg
    31801 gagatcagga acgcctacaa tttgattggc acaaatcgct gctaaatggt ctgttccccc
    31861 taaccatcgg tggaggaatt ggtcaatcgc gtatggccat gtttttgctt cgtaaaaagc
    31921 acattggaga ggtccaaaca tcggtgtggc cacaagaggt tcgcgatacc tacgacaata
    31981 ttttatagat gatacagagg ctaggttttt acctatagcc tctattttta ataaggtgat
    32041 aattcactag agctaatttg atgctatgtg agctagtcag ttatataata ggtcagaaat
    32101 ttgaaaaaat gaagcatttt taaggcttga cactagattt ttgttataat aacagttatg
    32161 agaattgtat caggtgaatt tggagggcgt cccctaaaaa cgctcgaagg caagactact
    32221 cgccccacat cagataaggt acgtggcgcg atttttaata tgattggtcc ttattttaag
    32281 ggtggacgtg tcttagactt gtttgctgga tcaggtggtc tatcaataga ggctatttct
    32341 aggggcatgt cagaggcagt gctggttgag cgtgatcgta aggcgcaagc cattattcaa
    32401 gctaatattg agatgacaaa agctagccag caatttacgc tattaaaaat ggacgctgag
    32461 cgtgcgtttg atcacttatc cgggcagttt gatgtggtgt ttttggaccc accctatgct
    32521 aaggagacga tagtagctaa tattgaggcc ttggtggaga aaaatctttt gagcgatgag
    32581 gtgatgattg tttgtgagac ggatcggtca gtagctctgc cagaggaaat tgcctggcta
    32641 gggatatgga aagaaaaaca atatggaatt agcaaggtaa cagtatatgt caggtaagat
    32701 tggactttat acagggtcat ttgacccagt gacaaacgga cacatggata tgattaagcg
    32761 tgctagtcat ttgtttgagc atgtttatgt cgggattttt aacaatccaa ataagcagag
    32821 cttttttact tttgagctgc gagcgcaaat gctaagagaa gcggtctgtg ccttgccaaa
    32881 tgtgacagtg gtttctgccg agcatggtct tgcggttgat ctggctaggg agctgtctgt
    32941 gacccacctt atccgagggc ttcgcaatac agctgatttt gactatgaga taggcttaga
    33001 gtattttaat catagactag cccctgatat tgagaccatt tacctgatgg caaatcatga
    33061 cctgcagccc attagctcca gtcgtatcag agagttgatt gcatttagag cgccaattac
    33121 tggtttggtt ccgcaggctg ttattaatca agtggagaaa atgaatgaaa acaataaaaa
    33181 aatttaaatg gtggctgatt ggcttagttg ccttgctttt tctactgttg acactgtttt
    33241 tccccttgcc ttattatatt gaaatgccgg gtggagccta tgatattcgc tcggtattga
    33301 ctgtcaatgg caaagaggat aaggaaaagg gagcttatca gtttgttgta gtgagcctca
    33361 gtcgggccac cttggctaaa ttgctctatg cttggctaac gcctttcact gagattagca
    33421 ccatggaaga tactactggt ggctatagcg atgctgacta cctgcgaatt aatcgctttt
    33481 atatggaaac ctctcaaaac agcgctgttt atcaggccct tactctagca ggcaaggagg
    33541 taagctttga ttataagggt gtttatgtct tagacgtcag caaggattct agctttaaag
    33601 gtgtgctgca cctagcagat acagtgacag gtgtcaacgg taaaacattt acaacgtctg
    33661 ccgatctgat tgattatgtt tctcatttga ccttgggaga tgaggtgcag gtacaattta
    33721 caaccgctgg tgagtcaaag actgaaaaag gaaagattat taagcttaaa aacggtaaaa
    33781 atgggattgg cattaccctg acagaccaca cacaggtcat ttctggtgat gaggtcgact
    33841 ttagcaccgg aggtgtgggt ggaccaagtg caggcttgat gtttactctt gatatttatg
    33901 atcaaatcaa tcacgaagac ttgcgcaagg gacgtgtgat tgctggtaca ggaaccattg
    33961 gcaaggatgg aaaagttgga gatattggcg gggcgggcct aaaggtggct gccgccgccg
    34021 ctgctggtgc tgatattttc tttgttccaa ataatcctgt ggataaggac gtcaaaaaag
    34081 caaatcctaa ggctattagc aattacgagg aggctaaaaa agcagctaaa cgactaaaga
    34141 cagcaatgaa aattattcct gtaaaaactg ctcaagatgc tataagctac ctcaaaaaat
    34201 agaagcaatg cgaagcaggc taatagggca tgctctgtct tgcttctagt tgggagctta
    34261 gcgacctcaa aggttttgag acctaagcat aaggtctggg cagggcattc tagagctaga
    34321 ctggttgctt gatcctgcac aaggaagatc gccaaggaag aataacctcc tcaggctgaa
    34381 atagtctgta ggaaaatttt ccaccattta ttaagacttt ttgaagaaaa tcacttaaag
    34441 acagtaaggt attaggcttt actgtcttag tttttcttgc ctgcagttat ggctgctgct
    34501 gacaccgcat caagacttga tagccagcag agcacaagga gcagctttgg cttaggttta
    34561 ttttctctgc tgactagtaa agaaggttgc tgtcagtctg cttacaaaaa cctaaaaata
    34621 gtgtataata ggtaggctat gggctgtcag gagtcgctag cctgcttacc cagaccagcc
    34681 ctttgagaag agcaagcatg gctcttctca gaataaccca ggattaacag acatcaaaat
    34741 taatgctaag gaaaggagct atatgaaaag agatatttta ccagagatgt ataattacaa
    34801 taaatttccc ggtccggaat ttattcattt tgatcattat gtcaaggctg aaggcattga
    34861 gttattgctg ctgaaaaatg aaaaaaatgc ttttaacaca acgagctttg gtcagcgctt
    34921 cacagagata ttattaaagt atgactatat tgttggagat tggggcaatg aacagctgcg
    34981 tctcaagggc ttttacaagg atcatcatga tgtcaaaaaa gctagtcgta tttctcgcct
    35041 agaagactat atcaaagaat tttgtaactt tggctgtgcc tattttgttt tggaaaaccc
    35101 taatcccaag gacatgccaa aagaggagga aaggccatca aggcgcagga aatcgtctaa
    35161 agccaatcgc cgcagaaatc agcctcagca tagtcagcag gcacctgcta aagacaactt
    35221 caaaaagcta accaaggata ggtcagcgga caagccaagc tttaccagca aaaagcgccc
    35281 agctcctaat aagaccaagg gaaaccaaag gcgctctcgt actagtcaac tgaaccataa
    35341 aacggatcac tttatcatca gaaagaagga caattaatct atgaaaccat caatctatgg
    35401 cctaacgcgc gacgagctaa ttgcttgggc gattgacaat ggtcaaaagg cattcagagc
    35461 gacacagatt tgggactggc tttacagaaa acgggttcaa tcctttgatg aaatgactaa
    35521 tatttctaag gaatttcttg ccattctaaa ggacagcttt tgtattaatc ccttgaagca
    35581 gcgtgttgct caggaatcag ctgatggaac ggttaagtat ttgtttgaat tgccagatgg
    35641 tatgctgatt gaaacggttt tgatgcgtca gcactacggg cagtcggtct gtgtaaccac
    35701 acaggttggc tgtaatatag gctgcacctt ctgtgctagc ggcttgatta aaaagcaacg
    35761 ggatttaaac agtggtgaaa tcactgcaca aattatgatg gtgcaaaact attttgatca
    35821 gcgtggccaa gacgaacgcg ttagccatgt tgttgtgatg gggattggag agccctttga
    35881 taattatcaa aatgtgatga cctttcttcg gacgatcaat gatgatcatg ggcttgctat
    35941 tggtgctcgt cacattactg tttcaacctc aggcttggct cacaagattc gcgaatttgc
    36001 caatgaagga gtccaagtca atctagctgt gtcactgcat gcacctaata atgagctacg
    36061 ctcaagtatc atgaggatca atcgctcctt cccacttgat aagctctttt cagcaatcga
    36121 atattacatt gaaacaacta atcgtcgtgt gacctttgag tatatcatgc ttaataaggt
    36181 taatgatggg gtagagcagg cacaggaatt ggcagatttg accaaaagga ttcgcaagct
    36241 gtcttatgtt aacctgattc cctataatcc tgtctcagag catgaccaat acagtagaag
    36301 tcctaaggag cgtgtggcag ccttttatga cattctaaag aaaaatggag tgaactgtgt
    36361 cgttcgtcag gagcatggta cagatattga tgctgcctgc ggtcagctgc gctctaatac
    36421 catgaaaaag gaccggcaaa aagcggcagc tgcaaggaca tgatgacttg gtcaaggttg
    36481 ctgatttgat tgataggaga tggagataaa aatctgaccc caaataaagc aaacaaacag
    36541 gtctagtttt ctgagatccc gaaagcaggt cttgttcgtt ttttaatgaa tgagactagg
    36601 tcataaagta catgcgttaa gaatgtctaa agtgcagctc tttttatccc agctcctctc
    36661 tttgatcttg gtagcagttg tcaagtaatt gctaagcaac ggtgttttat ctttattggc
    36721 tgtaaaaaaa gatatagtgc ctttattcac accttttctg aaacacttga gcttttgatc
    36781 gttccttttg gtgcttctgg tttcctaagc ttttcagtac catgaatcga ggcaaaataa
    36841 taggtgttag ccctagctgc ttaatgtagc tagggctttt gtgacctagc tgccagtaag
    36901 cctttcaaat agcaatatgg tcataaggcc cagtgtcaga tagggaataa aagggatttt
    36961 cttagtttgt agaagtaggc aggctagaat tccgatcaga ctggcaattt ggacgatcca
    37021 taacaaagag ctaagcttga ccacaagagc aagattagct aggtaaagaa aatctccggc
    37081 accaatattg ataggaaaag ctacgcttag cagtgcaagc aaaagcaata gcactgttaa
    37141 caggttaatg ctataaaatg gcagcagcaa caaaaagctc atcagccaga tgagcaaagg
    37201 atactcttga ctgtctaaat caaaaaagca cagtagcaaa gagaagcata ggagataaag
    37261 ctgtgtccag gtcaagccgc aaagggcaga cagtccgaaa atgaggctgg tgattatttc
    37321 taaataagga agcataaccc agtgcttttg ttcatgttta gagttgtaag tgggctttgc
    37381 cataggaaaa aagaggcttg aaagatgaag ttgacctata tggagcttga cccaagcctt
    37441 tgcttgctgt tcagaaaaca ggttaagtat tagccgaaag aggtttccca caagaaaacc
    37501 acaatagcaa taaaaaatag tgttcatact tatttatccg aaaaacaatt taaattcttg
    37561 caatatttta aaaaacggtg tacaatgaaa ctataaaacg agaatgattc taaataagct
    37621 gttgatactt atctgaattg gctcgttatc gtcgaatgga gctgacaaga gagtgacttt
    37681 tcttgctgca taccattcat gcccttttat atctatcagt aaggagagtt tattatgaca
    37741 aacacactcg ttgaaaacat ttatgcatca gtaactcata atatttctaa aaaagaagca
    37801 tcaaaaaatg aaaaaaccaa ggctgtttta aatcaagcag tagcagatct atctgtagca
    37861 gcttcaattg ttcatcaggt tcattggtac atgcgtggtc ctggcttttt atacctgcac
    37921 cctaagatgg atgagctatt agaccgcttg aacgcgaacc tagatgagat gagtgagcgc
    37981 ttgattacta ttggtggggc accctactca accctagagg agttttcaca gcattctaag
    38041 ctagatgaaa caaagggaag ctatgataag tcagtagctc agcatttagc tcgtttggta
    38101 gaggtttacc tttaccttac cagtctttat caggttggtt tagacattac tgatgaagag
    38161 ggtgatgctg cttcaaatga tttgttcaca gcagcaaagg ctgacgctga aaagactatt
    38221 tggatgctac aggcagagcg tggtcaaggt cctgctattt tctaaagcgt catacaactg
    38281 atataacata aaaaaggcag agcgtggtat agccctgtct ttttaacgcc tttaaaggca
    38341 actattagtg ctagtgatgt caggtctcac agctttttta tgatagatga ccaacatttt
    38401 tagaccttgt caccacagca gagcatgtgg catttagtcc accttgggct cacgtcgatg
    38461 gtcttactta tgatatatca aggcttgtga cattaccgtt gccttttatc ttcagtctga
    38521 gctgctggtt cctactgctg atgctgcttg atagtgttat agtgattttc agaaatatgg
    38581 aaagcgattg cataattgtc ttgaaatctc atgcgtaatt tgctaaaatc tagttatatg
    38641 aaaacattat acgatgtaca gcagctgtta aaaggctttg gtattgttat ctacatggga
    38701 aagcggcttt atgatattga aatgatgaaa atagagctgc aaaggctata tgatggtggc
    38761 ttgttggata aacaggctta tttaactgct gagctgattt tacgacgtga gcatcgatta
    38821 gagctaaaaa gagaagggca agaaaatgag tcaaaaattg atagggattg atttgggcgg
    38881 aaccacgatt aaatttggta ttttaacctc agagggtgac gttcaggaaa aatgggcgat
    38941 tgagacaaat gttttagagg acggtaaaca tatcgttcca gatattgtcg cctcactcaa
    39001 gcatcgcctt gacctttatg gactgactaa ggacgatttt atcggtattg gtatgggctc
    39061 acctggagct gtcaatcgca cagatcatac tgttacgggg gcctttaacc tcaactggag
    39121 aggcacccaa gaggtgggat ctgttattga aagggagcta ggaattccct ttgctattga
    39181 taatgacgca aatgtcgcag cccttggtga gcgctgggtc ggtgcaggtg acaataatcc
    39241 tgatgtggtc tttatgacct tgggaacagg tgttggtggt ggtattatcg ctgatggcaa
    39301 cttgattcat ggtgtggctg gcgcaggtgg tgagattgga cacatggtag tagagccgct
    39361 taagggcttt gcctgcacct gtggttcaca gggctgcttg gagacagtgg cctctgctac
    39421 aggtgttgtt aaggttgctc gtctgttagc agaagcctac gaaggagatt cagctatcaa
    39481 ggcagctatt gataatggag aagcggtctc aagcaaggac atttttgttg cagcagaggc
    39541 tggtgatgct tttgccaact ctgttgttga aaaggtcagt tattatctag gactggcagc
    39601 ggctaatatc tcaaatattt tgaaccctga ttcagtcgtg attggtggcg gtgtgtccgc
    39661 tgcgggagag tttttacgct cacgtgttga aaagtacttt atgactttta cctttccgca
    39721 ggttagacag tccactaaga tcaaaatagc agagcttggt aatgatgctg ggatcattgg
    39781 tgcggccagc cttgcaagac aatttatcac agaataggag ttaatgatgt caccacttac
    39841 aattattggc tgggtattat ttgcgggagt gattgcctat tacctttgga attatgtttc
    39901 ctatagaaga atggcaaagc aggttgataa tgataccttt aaggagctga tgcgtcaggg
    39961 gcaagtgatt gacctgcgcg atccagcttc ttttagggca aggcatatcc taggcgctag
    40021 aaattttcct acccagcagt ttgctacctc tattaaggct ttgagaaagg acaagccaat
    40081 cttgctttat gaaaatgtaa gacctcaata tcgggtcaaa gcagtcaaaa cattacgtaa
    40141 ggctggctat acggaccttt atgtcctaaa agcgggacta gattattgga atggtaaggt
    40201 taaatagcct tatagtcctt tttgctgagc taacgtttgc tgctatgtgt cggaacgttg
    40261 caagcagcag cttatctaag tttgtcatgc tagtttcaat ttcacaatcc aaagctactg
    40321 accatatcaa caacgcagct gtttttaggt gtcggcagga gtttttgtta gcttctttag
    40381 ggattgtttt taagtgatgt agagaggccg ttctgagaga aagccttgta gttagaaaaa
    40441 gagatgagaa agctaaggct cttgctgctg ttgtaagagt tagctttctt tttctttttt
    40501 gtgtggcgca ttcaagggct tgaaaacatt tacaattccc tcaggtcggt tttttaaaaa
    40561 aatttgtgtt atactgtttt agttaaaact atttatgcta caagaggaaa aaatgacaaa
    40621 atttagagaa gatattcgta acgttgctat tattgctcac gttgaccatg ggaaaacaac
    40681 gctcgttgat gaattactaa agcaatccca tacactagat gagcgcaaag agcttcaaga
    40741 gcgtgcgatg gattcaaatg accttgaaaa agagcgtggt attactattc ttgccaaaaa
    40801 tactgcagta gcttataacg atgttcgtat taatatcatg gatactcctg ggcacgcaga
    40861 ctttggcggc gaggttgagc gtatcatgaa aatggttgat ggtgttgtcc ttgttgttga
    40921 tgcttacgag ggaaccatgc ctcaaacacg ctttgtgtta aagaaggcct tagaacaaaa
    40981 cctaacccca attgttgtgg ttaataagat cgataagcca tcagctcgtc cggctgaggt
    41041 tgttgatgag gttcttgagc ttttcattga gcttggtgca gacgatgatc agctggaatt
    41101 ccctgttgtt tacgcttcag cgatcaatgg cacgtcttcg ttgtcagacg atcctgctga
    41161 ccaggaaaaa acaatggctc cgatttttga taccattatc gatcacattc cagcacctgt
    41221 tgataactca gctgagcccc ttcaattcca ggtgtcactt cttgattaca atgattttgt
    41281 aggtcgtatt gggatcggtc gtgtctttcg tgggactgtt aaggttggag accaggtgac
    41341 gctttcaaag cttgatggca ccactaaaaa tttccgcgtc actaagcttt ttggcttctt
    41401 tgggcttgag cgcaaggaaa ttcaagaggc caaggctggt gatttgattg ctgtttctgg
    41461 tatggaggac attttcgttg gtgagacgat tacgccaacg gattgtgttg aggctttgcc
    41521 tgttcttcgt attgatgagc cgacacttca aatgaccttc ttggttaaca actctccctt
    41581 tgctggtcgt gaaggtaaat gggtaacttc tcgcaaggtt gaggagcgtt tgcttgcaga
    41641 gcttcaaacc gatgtgtctc ttcgtgttga accgacagaa tcaccagata aatggattgt
    41701 atcaggtcgt ggtgagctgc atctatctat tttaattgag accatgcgtc gtgagggcta
    41761 tgagcttcag gtatcgcgtc cagaggttat cattaaagaa attgacggtg tcaaatgtga
    41821 gccttttgag cgtgtacaga ttgacacacc agaggaatat caaggtgcta ttatccaatc
    41881 cttatcagag cgtaaggggg atatgcttga tatgcagatg gttggtaatg gtcaaacgcg
    41941 tcttattttt cttattcctg cccgcggctt gattggttat tcgactgaat ttttatcaat
    42001 gacacgtggc tatggtatca tgaatcatac ctttgatcag tatctgccag tggttgctgg
    42061 tgagattggt ggacgccatc gtggagcgct ggtttcgatt gaaaacggta aggcaacaac
    42121 ctactcaatc atgcgtattg aagagcgcgg aacaatcttt gttaacccag gaactgaggt
    42181 ttatgagggc atgattgttg gtgaaaattc tcgtgacaat gatcttgggg ttaatatcac
    42241 aactgctaag cagatgacca acgttcgttc agcaacaaag gatcagacag ctgttatcaa
    42301 aacaccacgt attctaaccc ttgaggagtc tcttgaattc ttgaatgatg acgaatacat
    42361 ggaggtaacg ccagaatcaa tccgcttgcg caagcaaatt ttaaacaaag cagcgcgtga
    42421 taaagctaat aaaaagaaaa aatcagcaga ataaaggctg ctgattgatt tgagcgttac
    42481 gctctcttgc cgctttaacg agtaagtttg gccggcagag agctgaaagg agctttctgt
    42541 gttttatctt attattgcag ccttgattac ctcttattac ctgtttatgg caccaaagag
    42601 cgtccgtaac acactaggta tgattggttt ggttggtttg gttgccctat tgattgtgct
    42661 agctggctta agctttatca aaatcatgca gacgcccaag gaaattttcg ttggtctagc
    42721 catgatagta ttgggctact atgccctaag agacattcaa aaaatcccta aaaaaccaaa
    42781 gagtaaacat tagcatcaag cattgagtca aatcttaata gggtttgact ttttctgtct
    42841 ttgtactggt cttatgcgct gctatctgta aaatcttgaa aaagcagtta aataagggta
    42901 aaatagtagt caaatagaca tagatagtgt ggataaaaat gaagacaata acggaattcc
    42961 aaaataaaaa ggtattgatt cttggcctgg ccaaatcagg cgaagcagca gctaggcttt
    43021 tagcccggtt gggagctatt gtgacagtta atgatagcaa gccctttgag gaaaatcccg
    43081 cagcacaggc tcttcttgag gagggcataa gggttatttg tggtagccac cccttggagc
    43141 tgttagatga agacttttat tgtatggtta aaaacccagg gattcgctat gacaacccga
    43201 tggtggtacg cgccttagat aaggcaattt ctattctaac agaggttgag ctggcttatt
    43261 tggtatctga agcacctatc attggtatta cgggctcaaa tggtaaaacc actacaacca
    43321 caatgattgc tgatgtgcta aatgctgggg ctcagtcggc tcttttggct ggaaatattg
    43381 gctttcctgc ctcagaggtg gctcaagccg ctacagcaaa ggatacacta gttatggaat
    43441 tgtcttcctt tcagctgatg ggaactgagc agtttcaccc acatattgca gtcattacta
    43501 atctagtgcc tactcatctt gattatcatg ggagttttga ggattatgtg gcagctaagt
    43561 ggcacattca atatcgaatg accgacaagg actatcttgt gttaaatgcc gatcaagagc
    43621 tggtaaaacc actggcccaa aagaccaaag caagtcctgt ctttttttcc accaaagaaa
    43681 aggttgatgg tgcttatttg gcagatgggt atctttattt caaagaggag aggctgatgt
    43741 cagcagctga gcttggtgtt cctgggaggc ataacattga aaatgctctt gccaccattg
    43801 ctgttgccaa gctaagaggc atttctaacc aagtgatttc aaagaccctg tcacacttta
    43861 gtggtgtgaa gcatcgcctt cagttagttg ggacactgaa tcaggtgacc ttctacaatg
    43921 acagtaagtc aaccaatatt ttggcttgtc aaaaagcctt gtcgggcttt gataatagca
    43981 gggttatcct gattgctggt ggcttggatc gcggtaatga atttgatgaa ctggtgccag
    44041 acctcgttgg ccttaaaaag atgattcttt taggggaatc cgtagagcgt atgaagcgag
    44101 ctgcagacaa ggcgggagtg tcctatcttg atgccaaaga tgttgcagct gccactaaaa
    44161 tagcctttga gcaggcgaag cctggtgata ttatcttgct gagtccagct aatgctagct
    44221 gggatatgta tccaagcttt gaaagccgcg gcgatgagtt tttagcagcc tatgatgcgt
    44281 taaaaggaga ggcctaatga ccaagaaaat catttttacc ggtggtggta cagctggtca
    44341 tgtcacctta aaccttatcc tcataccgaa gtttatcaag gatggctggg aggttcatta
    44401 tattggtgat gacaatggta ttgagcatca ggagatcaaa aaatcaggtc ttgatgtcac
    44461 ctttcatgcc attgcaactg gaaaattaag gcgttatttc tcttggcaaa acctgcttga
    44521 tgccttcaag gtaggctttg gtatcgtgca atcgctcctt atcatagcta gactgaggcc
    44581 taaggctctc ttttcaaagg gaggctttgt gtctgttccg cctgttattg ctgcaaggct
    44641 cttaggggtg cccgccttta ttcatgagtc ggatctttct atgggcttgg ctaataggat
    44701 tgcttatcgg tttgcaacga cgatgtatac aacctttgag caagagcaga cactggtaaa
    44761 gctcaagcat gtcggagcag ttactaaggt gacagctcct aagagtcgat cagtagcttc
    44821 taagcagctt acagctgttt cagagtattt tgatcctaat ttaaaaacac ttttgtttat
    44881 tggtggctcc gcaggggcta gggtgtttaa ccgctttatc actgaccatc ctgagctaaa
    44941 ggaagacttt aatatcatca atatctctgg cgatcctagc ttaaatgagc ttagccggca
    45001 tctttaccgc gtggactatg tgactgatct gtatcaaccg ctcatggaaa tggctgatct
    45061 ggtagtgact cgcggaggct ctaacacact ttttgaatta ttagcgatga gaaagcttca
    45121 gctcattatc ccacttggca aagaggccag tcgaggtgat cagcttgaaa atgctcatta
    45181 ttttacaaca aggggctatg ctgagcaatt attggaacag gaattgaccc tgcctcattt
    45241 tcaagagaag gtgagagaag tctttgctaa gcaatcggac tatttatctg caatgacgag
    45301 ctctagtgag ctccaatcac cagaaagctt ttaccagctt ttaagtgccg acattagctc
    45361 cgcgacaaag gaaaattaaa tggcagataa gacaaaacat tcagaagaaa aagctgcttt
    45421 gaccgaatgg caaaagcgta atattgaatt tctcaacaag aagcagcagc aggctgagaa
    45481 agacaaaaaa ctaaaagaaa aattattaaa tgaaaaaatt gcgcaagctc aaggagagac
    45541 agtttcaaag gctgaccaag aagaaggtac agatgaagct gaggagaaag ccgaggtaga
    45601 ccaagtcggc gctgatgagg gtgagcagct gccagaagca tcagagcagg aagtcccctc
    45661 cccaaaagac aagccattaa aggttccaaa agaaaaaagt ccaaggcagc aggctcttca
    45721 aaagggctgg ccagtgttac tggtgtcgtt tgtggttttg tgcctatcga tttttatgat
    45781 cacaccctat agtaaggtca aggatttctc cgtcaagggc aataaaaaaa caagcgttga
    45841 ggacttagtt agagacagtg ggatcaagtc atctgattac tggattactc tattagcctc
    45901 tccgggttct tatgaaaatg cgattttaaa agccaatccc tgggtgaaaa aggtggcttt
    45961 gcgttatggc tttcccaatc atttccgctt tgatgtgaca gagtttgata ttattgccta
    46021 cgctcgggta gctgaagggt ttcaaccgat cctagaaaat ggcaagcgag ttgctgctgt
    46081 caagcaggct gctttgccta aatccttttt gattttaaat cttgagcatg aaaaagagat
    46141 tcaagatgtc attaaccgct tgaccaaaat cccaagtgac ctagtcaagg ctatcaaatc
    46201 agtgtcatcg gccaattcac agacaactaa ggatttgctg cttcttgaaa tgcacgatgg
    46261 caaccttatc agggtacctc ggtcacagct tgagctaaag ctgccttatt accaaaaaat
    46321 caagaagaat cttgatactg ctagcattgt tgatatggag gttggtatct atacgaccac
    46381 tgctgaaatt gaaaacatgc ctgaggtgcc agcgtctgcc caagcttctc aggcagataa
    46441 gcctgctgag gcttcaccag agcagggtga agagcaggcc acacaggagc agcctagccc
    46501 tgaaacacct gctaatcctg aggccacaaa tccctcagtc gcccagccta ctgagcaggc
    46561 aaatcaacag taatcgttta gggtaagaga agggggcaaa aaagcattta aggctcttaa
    46621 attaggccct tgttgaacgg caaaaaaaca ttaagtttat ataacaaaaa acgtaaaatg
    46681 gtaacatttt acgttttttt atgatataat attccctgaa taattctgct ttttagcagt
    46741 gtttttgaat agtaaaagtt tggaaagtaa gtgaggtcga gtgaatggct agaaatggct
    46801 tttttactgg tttggacatt ggaacaagct cgataaaggt tttggtagca gaatttatct
    46861 ctggcgagat gaatgttatt ggtgtgagca atgttccgag tactggcgta aaagatggca
    46921 taatcattga tatagaggca gcagccgctg ctattaaaac tgcagtagaa caagctgaag
    46981 aaaaagcagg aatgacaatt gaaagggtca atgttgggct gccagcaaac ctccttcaaa
    47041 ttgagccgac acaaggcatg attcctgttc ctagcgaatc aaaagaaatc aaagatgaag
    47101 acgttgatag cgttgttaag tcagcactaa ccaagagcat tactccagag cgagaggtga
    47161 tttccttagt ccctgaagag tttattgtgg acggctttca gggcattcga gatcctcgtg
    47221 gcatgatggg gatcaggctt gaaatgcgcg gtctgattta cactggacca agcacaatcc
    47281 tgcataactt aagaaagaca gttgagcgtg ctgggattaa ggttgaaaac atcatcattt
    47341 ctcctttggc aatggctaag gcggtgttaa atgaaggtga acgtgaattt ggtgctacgg
    47401 tcattgacat gggtggagga caaaccaccg ttgcctcaat gcgagcacag gaattgcagt
    47461 acaccaatat ctatgcagag ggcggcgagt atatcacaaa ggatatctct aaggttctta
    47521 aaacatcaat gtcaattgca gaggccttga agtacaattt tgggcaggct gatatggcag
    47581 aggcgagtct gactgacact gttaaggttg atgttgttgg cagtgatgag cctgttgagg
    47641 taacagagcg ttacttatca gagattatct cggctcgtgt tcgccatatt ctagatcgcg
    47701 ttaagcagga tttagaaaga ggacgcctgc ttgatttacc tggtggcatt gtgctgatag
    47761 gtggcggcgc cattatgccg ggcgtggttg aggttgctca agagattttt ggaaccaatg
    47821 ttaagcttca tatcccaaat caggttggta ttcgtaaccc gatgtttgcc aatgtcatta
    47881 gcttggtcga gtacgttggt atgatgtcag aggtggacgt tttagcgcaa aatgctgtat
    47941 caggcgagga attgctaaga cgtaagccga ttgactttac tggccaagaa gcttacttac
    48001 cagactacaa tgaagctaga gggtttgagc cggctcctaa ttatgagcag caagtgcccc
    48061 aagcagacta cgagcctcaa gaacccgctg aaccaaagca aaagatttca gagcgtgttc
    48121 gtggcatttt tggaagtatg tttgattaaa agtaataaag tgaggaaata aaatggcatt
    48181 ttcatttgat acggcatcca ttcaaggtgc aatcattaag gtaatcggtg ttggtggagg
    48241 tggcggaaac gctattaacc gcatgattga tgagggggtt gcaggtgttg agtttatcgc
    48301 tgcaaacact gatattcagg cattaagctc atcaaaagca gaaacagttg ttcagcttgg
    48361 tcctaaatta actcgtggtc ttggtgctgg aggtcagcct gaggttggtc gtaaggcagc
    48421 agaggaaagt gaagaggttc tcacagaagc tctgactggc gctgatatgg tctttatcac
    48481 tgctggtatg ggtggaggct caggaacagg agcagctcca gtaattgctc gtattgctaa
    48541 gagcttaggc gctttgactg tggcagttgt gacacggcca tttggctttg agggcaacaa
    48601 gcgcagtaat tttgccattg aggggattca ggagctaaga gagcaggttg ataccttatt
    48661 gatcatctca aataataatc tgcttgaaat tgttgacaaa aagacaccat tgcttgaagc
    48721 gcttagcgaa gcagacaatg ttttgcgtca gggtgtacaa gggattactg atctgattac
    48781 aagccctggc ttgattaatc ttgactttgc cgatgttaag actgtgatgg caaataaagg
    48841 caatgcactt atggggatcg gtattggttc tggtgaggaa cgtattgtag aggcagctcg
    48901 taaggctatc tactcaccat tacttgaaac aacaattgac ggtgctgaag atgttatcgt
    48961 taacgtgaca ggtggacttg atatgaccct cacagaggct gaggaggcat ctgaaattgt
    49021 tggtcaagca gccggtcaag gcgttaacat ctggctagga acatctattg atgactctat
    49081 gagagatgaa attcgcgtaa cagttgttgc aacaggtgtt cgtcaggata aggcggagca
    49141 agcctcagga tttcgtcagc cacgcaccta cactcaatct aacgctcagc aggctgctgg
    49201 agcacaatat gcttcagagc aggtgagaca gactgcacag ccaagctttg atcgtcattc
    49261 atcaagcttt gattttgata tgggtgaaac acgtgagatg cctaagtctc agcaagctat
    49321 gccagctcat ggccacaatc ataatcaggg ctcagctttt ggaaattggg acttacgtcg
    49381 agacaatatt gctcgtccag cagaaggtga gcttgacaat caattgaaca tgtcaacctt
    49441 ctcatcaaat gatgacattg atgatgaatt agaaacacca ccatttttca aaaatcgtta
    49501 atgatggatt tacaaaaaaa taaggatatt gtttttgaaa atattcgctt agccactcag
    49561 gcagccaacc ggcctgaaaa cagtgtgtca gttatcgctg tcacaaaata tgtggacaag
    49621 gcagttgcag gtcagctgat tgatatgggg attgagcata tcgctgagaa ccgtattgat
    49681 aagtttctag ataaatatga agccttgaaa gataggcaag ttacttggca ttttatcggt
    49741 actttacagc gtcgaaaggt aaaggaagtg attaataagg ttgattattt tcatgcctta
    49801 gattcagtaa agctggcttt agaaattgaa aagagagctg accaccctgt gaagtgtttt
    49861 ctacaagtta atatttctga agaagaaagc aagcatggtt ttaagattgc tgagcttgat
    49921 gctgctattg aggaaatcag caagatggaa aagcttcatc ttgtcggtat catgacaatg
    49981 gcacctattg atgccagtca gcaagagctt agaagcattt tccaaaaagc aaatcaatta
    50041 agaaaaaact tgcagtcaaa aaagagaaag aatatgccgt ttacagaatt gagtatgggc
    50101 atgagtaacg attatccaat tgctattcaa gaaggctcaa cctttgttcg tattggaaca
    50161 tctttctttc actaaatgga gaataagatg gcaattaaag acgcatttaa taagatgatt
    50221 tcttattttg atactgatgg ggtcagtgaa gtagaagagg agctatcctc taaaaagcaa
    50281 gaagagcctg tgactaaatc acaacagacc agcagaccta atcagcagca acaagcagct
    50341 agagcgagtc agccccagca gcctaagcag gctagacctc agatgcaagc tcagcaaaga
    50401 ccacagtcac aatcaagagc tgcctatgct gagcgaccat atcaaggtca aagtcaagca
    50461 cgtgtttctc atgactacaa tgacagaagg gcgacgtcag ccccgtctgc ttctagtcgt
    50521 cgtgagcaat atcagcatgc tgctcatcaa gagcaaacaa ctattgcctt gaaatatcct
    50581 cgtaagtacg aggacgctca agaaattgtt gatctcttga tcgttaatga gtgtgtgctg
    50641 attgattttc agtacatgct agatgctcag gcaaggcgct gcctagattt tattgatggt
    50701 gctagtaagg tattgtatgg tactctgcaa agggttggct cttccatgta tctgttgacc
    50761 ccatcaaatg tatctgttaa tattgaagag atgaatatcc caaataatgg ccaagatatt
    50821 ggctttgatt ttgatatgaa gagacgctag tgtgatgatt tttatactgt tgatacttct
    50881 aaagctaatt aaggtttatt cctatttgct gctagcctat gccttactgt cttggtttcc
    50941 tggagcctac gactcttggc ttggcaggct ggtcagcgat atagtggagc ctatcttaaa
    51001 gccctttaga tcattgaacc tgcagtttgc gggcttggac tttactattt acctagtgat
    51061 gattggtcta aatgttttaa gtgagatctt gataagagtg ttgatctgat gactgttcaa
    51121 acaatgcttt atcagcattt tcagcctgat gaacacccat ttattgaaag aatgcttgac
    51181 ttgatcgctc gtgttgaggc taattatcta ttagaggtta ctgatttttt aaatccgcga
    51241 gaggtcacga ttttaaaagg cttagtcgca gcaaccaatc tgcagtgctt tagctctact
    51301 gattattatc ctagtgaata tggtcgtgtg attgttgctc ctgactatta ttgtctagat
    51361 aaggcagatt ttgatttggc tttgattgag gtgacctata atgctaagtt taatcagctg
    51421 acacatgcac agattttagg caccttaatt aatgaattgg gaatcaaaag agccttactt
    51481 ggcgatattt ttgttgagat aggtcatgct caggtcatga ttaatcgaca gctgttaagc
    51541 tattgtttag gaacgattgc taaaatagca agagctaggg tcaagctcaa agaaattgac
    51601 cttgatcagc tgttaaatct gacagctaat cagcaggttc tgactgatat aatggtatct
    51661 agcctacgcg ttgatcgctt gattgctact gtattaaagc aatctagaaa tcaggcgata
    51721 aggcttgttg aagcaggcaa ggtcaaggtt aactatcagc ttgtcactaa agcctctcag
    51781 cctgtagctg ttggtgattt aatcagcatt cgtggctatg gtaggtttag catactaaca
    51841 gacaatggct tcacaaaaaa tgggaaatat aagctaacac ttagcaaaat gatgcgtaaa
    51901 taaggagata taatggcact tacagcacta gaaattaaag ataaaacgtt taagacaaag
    51961 tttcgtggct acagtgaaga ggaagtaaat gaatttcttg agattgttgt agacgattat
    52021 gaggctttgg ttcgcaaaaa tcgtgataat gaagctaaga taagagagct tgaagaaaag
    52081 ctgtcttact ttgatgagat gaaggaatca ttgagtcaat ctgttatcct agcccaggaa
    52141 acagctgaaa aagtgaaatc ctcagcaaat gctgaagcaa ccaacttggt cagcaaggca
    52201 acctatgacg ctcagcattt gcttgatgag tcaaaagcaa aggctaacca actattgcgc
    52261 gacgcgacag atgaagcaaa gcgcgttgct attgagacag aggaattaaa gcgccagaca
    52321 cgcgttttcc atcagcgctt ggtttcagct attgagtcac agttaagctt atccaattcg
    52381 cctgagtggg acgaattgtt gcagccaaca gctgtctacc ttcaaaactc tgatgcagcc
    52441 tttaaagagg tggttaaaac tgtccttaat gaggatattc ctgaggctga tgacagcaat
    52501 tcctttgatg caacacgtca gtttacacca gaggagctag aggagctgca gcgtcgtgtt
    52561 gaagaaagca ataaggaact agaagcctac caggtgcagc gagaagagca agctagcgag
    52621 cctgaagtga acctaagcga gacacagacc tttaaattga atatttaatc ataagaaaaa
    52681 caggattgaa tgcccaaaat cacagcaagt aggagatgat gagagtccta tattccctga
    52741 gcataacaat tatcattttc ttcaatcgtt actgaatgat agtaagtgac gagggaggct
    52801 caccttacga gcaaagaggg aacagcaaaa gggattttgc tgttctgaat taaggtggta
    52861 ccacgagctt tcgtcctttt tgagacgggg ctttttttgt aattctgata agatattgac
    52921 taaaaggagt ttgacaagat gaaattaaaa gaaacactta acttaggcaa aactgccttt
    52981 ccaatgcgtg ccggtctacc caacaaggag ccacaatggc aaaaggcttg ggacgaggct
    53041 gagatttaca aaaaacgtca agccttaaat gaaggcaagc ctgcctttca cctgcacgat
    53101 gggcctccct atgcaaatgg taatatccat gtcggacatg cgctgaataa aatttcaaaa
    53161 gacattattg tacgtgccaa atctatgtca ggttatcaag cgccttttgt tccaggctgg
    53221 gatactcatg gccttccaat tgagcaggtc ttggctaagc agggggttaa gcgtaaagag
    53281 atggatctgg ctgactatct tgacatgtgt cgtcagtacg cgctaagtca ggttgataag
    53341 caaagagacg acttcaagcg tctcggtgta tctgctgatt gggacaatcc ttatgtgacc
    53401 ttagacccaa gctttgaagc cgatcaaatt cgtgtctttg gtgcgatggc tgataagggc
    53461 tacatttatc gtggggcaaa gccggtttat tggtcatggt cttctgagtc tgctcttgct
    53521 gaggcagaga tcgaatatca tgatattgat tctacatcac tttactatgc taatagggtt
    53581 aaagatggta agggccttct tgatactgac acctatatcg tggtttggac gaccacacca
    53641 tttacggtaa cagcttctcg tggtctaaca gttggacctg atatggatta tgtggttgtt
    53701 agacctgcag gctcagaccg taactatgtg gtggcagaag gactgctaga cagtctggct
    53761 gctaagtttg cttgggaatc atttgagatt ttggccaatc ataagggctc tgacttggaa
    53821 tacattgtaa ccgagcaccc ttgggacagt gaggttgatg agctggttat tcttggtgat
    53881 cacgtaacct tggattcggg tacaggtatc gtccatacag cacccggatt tggtgaagat
    53941 gactacaatg ttggtatgac atatggactt gaggttgctg ttacagttga tgagcgtggt
    54001 ttgatgatgg aaaatgcagg tcctgatttt catggtcaat tttatgacaa ggtgactccg
    54061 attgttattg aaaagcttgg agatctattg cttgcccaag aggtgatcaa tcactcctat
    54121 ccatttgatt ggcgcacgaa aaaaccaatt atttggcgtg ctgttcctca gtggtttgct
    54181 tctgtgtctg acttccgtca agatattcta gatgagattg acaaaacaac attccacccg
    54241 acatggggaa agacacgact ctacaatatg attcgtgatc gtggcgattg ggtgatctct
    54301 cgtcagcgtg cttggggtgt tccactgcct attttctatg cagaggacgg cacagccatt
    54361 atgactaagg aggtaactga tcacgtcgca gatctgttcc agaagtatgg atccattatt
    54421 tggtggcaaa aagaggctaa ggagctttta cctgaaggct tcacgcatcc aggctctcca
    54481 aatggggtat ttaccaaaga aacagatatc atggacgtat ggtttgactc agggtcttct
    54541 tggaacggtg tgatgaatgc tcgtgatcat cttgcttatc cagctgacct ctaccttgaa
    54601 ggctctgacc aatatcgtgg ctggttcaac tcatcactga ttacctcagt tgcagttaat
    54661 gggcatgcgc catataaggc tatcctatca cagggctttg tccttgatgg caagggtgaa
    54721 aaaatgtcta aatctaaagg aaatatcatc tcacctaatg atgttgctaa gcaatatggt
    54781 gctgatattc tccgtctctg ggtagcttct gttgatacag ataatgatgt gcgcgtgtca
    54841 atggatatcc taggacaggt ctctgaaacc tatcgtaaaa tccgtaacac gcttcgcttc
    54901 ttgcttgcta atacatcaga cttcaatcca catacagata aggtggccta tgctgagctt
    54961 gctgctgttg ataagtacat gactatcaag tttaacaagc tagtaggggc tatcaatgac
    55021 gcctatgagc attatgactt tatggcgatt tacaaggctg tggttaactt tgtgacggtt
    55081 gacttatctg ccttctacct tgattttgcc aaagatgtgg tttacattga ggcagctaac
    55141 agcctggcac gtcgtcgtat gcagaccgtc ttttatgata tcttggttaa tatcactaag
    55201 ctattgactc cgatccttcc gcatacggca gaggaaatct ggtcatattt agagcatgag
    55261 ccagaagact ttgtacagct atcagagctg ccacaggctc agacttttga taatcaagat
    55321 attattctag aggaatggga agcctttatg acgcttcgga cacaggcgca aaaggctttg
    55381 gaggaagcgc gttatgacaa gattattggt aagtccttag aagctcatct gacaatttat
    55441 gcaagtccag aggttaagac actgttgaca gctctagata gcgatattgc actgctattg
    55501 attgtctctc agctaaccat tagtgaggag ccagctcctg agaatgctgt cagctttgat
    55561 gatgttgcct ttacggtagc tcgtgcgcaa ggagaggttt gtgagcggtc acgtcgtatc
    55621 gatccaacaa ccagaatgcg gtcttataat gcctttgttt gcgaccacag tgcgaaaatt
    55681 atcgaagaaa acttcccaga agcagtagca gaaggctttg attctgccac taattaagca
    55741 gtcagaatta atagtaatca taagttttta ttgggagtct ggatgatgtt tatccaggct
    55801 cttttaatat tgtctcgtca agcacctgat tgtcagcttt atcaaaaaaa gaaagcatag
    55861 ataagcatga gacaggctgg tgtgataagc tttcctgaaa tctgggctca gttagtcgcc
    55921 acgacagccg catgaaagat gtttagcaag aaaagaaggc tttgctgtat ttcatgttcc
    55981 gctatttcaa gcatatgtct tattttgtat aggaaaaagg ttgaaaggat ctgctttact
    56041 ctatattatt attcggaaat aactgtttcg tgcatttggc atggcttacc tgctgacctt
    56101 tgttgacagg tgccctttag ccctatctaa tgtctagagc agtcttatga atccagcttc
    56161 aaaaaagaag caaagatagc ctcacattag ttctataatg tgaggctatc tttgcttgtg
    56221 gttgtttggt ttgaagcgtt agctatgctg tcaagagata aaaaagccca gaccgctctc
    56281 gtgtggtcta gacctcaggc tccgaaaaag gctgctttta tgggcttgta cagacagcaa
    56341 gagcagccag ctttgacata tgatatgaca gctaaggctt gatcgcaaca gaaggctaga
    56401 cagaggtctg gaaggaaatt tcgatcaaat tattggtgtg caaggttttt gagtgacctg
    56461 gaatcacaat agattggtca atcttacgtt ttaagaaaaa ttcgcgaatc acctcaagct
    56521 cgtcctcttt gatagcgcga tatttatttg agatgagtag ctcataatgc ttaggtgctt
    56581 gggtgaagat gacgtcagta ttgccagctg agtacacctc aacgaggtga gcatctgtat
    56641 tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata agtctcataa
    56701 atcttctcct gactattttt acttttatta tagcactatt tttaaattga ttacggattt
    56761 taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg ctttaagact
    56821 gttatggcgt ccgcaatagg aaaccaagcc agatggttaa agtcttccaa gggctttgag
    56881 atagcttgga atgatgtcac ctcgtacagg taggcaggat tatagtagta ggtatcgcgg
    56941 tgacgagaat agaagtattc gtctgcttga ccataataat aaccaatatc agcagcaaat
    57001 cccagctcct caacgagctc acgctccagt gcctgtagct ggctttcacc agtctctatt
    57061 tctcctcctg gcaaaaacca agcaccattt ggagcctgca ccaggataat ctctgtttta
    57121 gccgagttag gaatcactgc atagacaccg taacgtgcag tgtaatgctg gtcatctatc
    57181 ttgtcaccaa atattggaac ggtcatatcg cttctccttt attttattat actaaatttt
    57241 tggtcattat tctcataaaa ctgtagattt atcaaaaatg tttcataaaa aaatgctcgt
    57301 caaaaagaga gaaaatgctg tctgcttttc tctctgcttt tggtatcccc tgttagtccg
    57361 cctgcttcgc ctgagatttg actacaggct tgattataat gtgtccatta gaggtcagga
    57421 cagctcgcag gtctttttct gctgggtgct caaggtagaa gtcggtaatg gcatcctcaa
    57481 tgtagtcctg aatggtgcgg cgcaatggtc gtgctcccat cttaggatca tagcctagct
    57541 caacgagctt ttctttgacc ttttgggtga catcaaggcg aatgttattg tgagcaaggc
    57601 ggtggttaac atcatcgagc attaaatgaa cgatatgtaa aagattgtcc ttgcttagtg
    57661 gctgaaactc aataatgcca tcaaagcgat tcatgaactc ggggctaaag aaatgactga
    57721 gctctcctaa aacagagttt gtccgccctt ctctagcagc gccaaagcct actgaggcct
    57781 ctgttttgcc agtgccagca tttgatgtca tgatgataat agtgtcctta aagctaacgg
    57841 tacgtccttg tccgtcggtt aatcgtccgt catctaggac ctgtaaaaac atgtgcatga
    57901 catcagggtg agccttttcg atctcatcta acaaaatgag cgagtaaggg ttgcggcgca
    57961 cctgctccgt taactgacct gcctcctcgt agccgacgta gccgggaggg gcaccgacaa
    58021 gcttagccac agcgtgcttt tccatgtatt cagacatgtc aaagcgaatc atgttatcag
    58081 cagagccaaa aagctcaatg gctaattgct tggaaagctc tgttttaccg acaccggttg
    58141 gtccaacaaa gaggaaggag ccgataggac gatttggcgc tccaagtcca acacgattac
    58201 gacggatagc ttttgcaatt ttatcaacgg cgtcgtcttg accgataaca tgctttttga
    58261 gatcggcagc cagattgact agctgtgatt gttccttttc ctttaaatca ccaactggaa
    58321 tattggtttt ttgctcaacg attgcttcga tggtcttatc ggtaatgatt ggagtatcct
    58381 gctcatctag cttttgagcc tgcatttctt tgtatttggc gatttgatcg cggaagtagg
    58441 ctgctcgctc ataatcctca tcacgtgtgg cttgtgcctt aaggttttct gcctcaatca
    58501 aacgcttgtc gatgtctttt gggtcaacaa agttaagggt taggttcatt tttgagccag
    58561 cctcatctag taggtcaatg gccttatcag gcaagaagcg gtcttgaata tagcggttgg
    58621 ataggttggc ggctgcttcg atagctgact ggctatattt gacatggtga tagtcctcgt
    58681 atttggcttg gattcctttt aggatcgtga ttgtttcttc aaccgagggc tcatctacct
    58741 taaccggctg catgcgtcgt tcgagggctg cgtccttttc gataatgcgg tattcattga
    58801 gagtggtggc tcccactaat tgaagctcac cacgagcaag tgctggcttt aaaatatttc
    58861 ctgcgtccat actgccatca ccaactgccc cggctcccac aatttcatgg atttcatcaa
    58921 taaaaaggat aacgtcatgg cgcttgcgga tttcctccat gagcttttgc atgcgctctt
    58981 caaattggcc acgaatacct gtcccctgaa cgaggctaac cacatcaagg cgaatcacct
    59041 gcttactctg tagcttttgt ggcacatcac catcaacgat tttttgagca aggccttcaa
    59101 cgacagcagt cttaccaaca cctggttctc cgattaggac agggttattt ttggtacgac
    59161 ggttgagaat ctcgatcacg cggataatct catcgtcacg tccgatgaca ggatcaatat
    59221 caccacgctt agccatttca gtgatattaa tgccgaattc ctcaagcaaa cctttgttag
    59281 tctcttgtgc tggctgtgtg tgattgggac ggtagccacc gttgtgacct ccgccatgct
    59341 ggcctcctga ttgggtaggt ggtgtattgg ggagctgacc aaaggctcta aagttgttga
    59401 ggtcaccaaa aaagtcatca aagaaagggt tttgagactg ctgctgggcc ttttgattgc
    59461 cagtatagcc tcccaggata ggatttttag ggtctgtttt catgatttgg tagcaatttt
    59521 gacagaggtc aatctgcctt tgctttccgt taatgcttgt ataaagatga atggttgatt
    59581 catttaaatt acagttttga caaagcatat catacctcca aggggttatc taaaaagtca
    59641 aggtcattta gtcaaaaatg gtcaaacttt atagtcatat tatagcacct taggcttgga
    59701 aatcaagtaa aaagcttcat tattagcact ttcaggtata gagtgataat ctctataaat
    59761 cttgctgctc attggttcaa aaaagtcgtc aaaggggata aaataaagag aaaatggcta
    59821 cttttcttgt ttgtttgcga tgatttatgt taaaatatat agggacaata aacgaatagg
    59881 agaaacgaaa tggaatcaca tttagtgaga atcatcaacc gtctggagct gatggtgaca
    59941 gatggcggta atttaaagag aaattttgag cgagatggtg tcgttgttgc agaggttgca
    60001 tttgtcaacg atcctgaaaa tggtccagtc tttattttac gtgatattga agcgcgtgag
    60061 tcatactcat ttgacagcat tgacttgatt gcgatggaaa tttacgattt gttatattaa
    60121 gctattgatg atgacatggg cttgctggga ggcaggtcca acagaggaca agctggtgat
    60181 ttactggttt gtttttatta ttccttaaag ccctctttct cctatacctt gtctagctgt
    60241 agggtttgtg ggtgagcagt gctgccaaag gccctgtggc ttggttcttt ttcagggctt
    60301 gtgataatcc tgctgacagc aaaggctctt agctgagtga tttaaggtca gccgatcatt
    60361 tctgtgctgc tctaatgcag cttttttaac aatttggata gcttttgaga gcccttagaa
    60421 aagccattgc taagggcttt gttatgccta tctgttggtg tctaaaagag cagtgatacg
    60481 ataaagagag gtcagaaaag acctctctga tgtttgtgat tagctgttag ctattaccat
    60541 aggggaaaga tacaatggct agcttagctt ttctttctct ttaggtttag cagacctgcg
    60601 ctagcgatga cgctaagggc tgcaagggtg aagaatgggt gatttgtctc ccctgtagct
    60661 ggtagcgtgc tcttttgagc tgctgatttg cttggtgctg acttaggcgc tggtgcctta
    60721 ggctgagctg atttttctgg agcctttggt gtaggagcct tttcaggtgc ttttggagct
    60781 gatggtttgg tatcctttcc ttggtcaccc tttggctgtt gctcgccttt ttcaccgcgc
    60841 tgaccttgct cgcctttttc accacgttgg ccttgctcac ctttttcgcc acg
//
LOCUS       DARYSY010000003        58753 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYSY010000003 DARYSY010000000
VERSION     DARYSY010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58753
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..2507)
                     /locus_tag="TVR04_000126"
     CDS             complement(<1..2507)
                     /locus_tag="TVR04_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1268849.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKLVQTS
                     PSVSAIDALHYLSENSKKEFKEELSKVEKAQPEKLKEIVSKAQQADKQAKTLAEMKVP
                     EKIPMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSL
                     FWQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDAQKYPNTPEGNKALAKAI
                     VDEYVYKYNLDGLDVDIERDSIPKVNKEESKEGIERSIQVFEEIGKLIGPKGADKSRL
                     FIMDSTYMADKNPLIERGAPYIDLLLVQVYGTQGEKGGFDNANHKAVDTMEERWESYS
                     KYIRPEQYMVGFSFYEEKANSGNLWYDVNVEDDTNPNIGSEIKGTRAERYAKWQPKTG
                     GVKGGIFSYGIDRDGVAHPKKNGPKTPDLDKIVKSDYKVSKALKKVMENDKSYELIDE
                     TDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPAIQSLEGLNKLKKLAKLELIGLS
                     QITKLDSLVLPANAKPTKDTLVSGLETYKNDDRKEEAKAIPQVALTISGLTGLKELKL
                     AGFERETLAGIDAASLTSLEKVDLSKNKLDLAAGTENRQIFDTMLATVTKHGGVSEKT
                     FVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSEADYKAYQ
                     EQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETYKVEFFSP
                     TNSTKPVHEAKVVVGEEKTMMVNLSEGATVIGGDADPTNAKKVFDGQLGSPTDNIFLG
                     WDSKKSIIFKLKNSGIVKHWRFFNDSARNPKTTNKLV"
     gene            complement(2737..4620)
                     /locus_tag="TVR04_000127"
     CDS             complement(2737..4620)
                     /locus_tag="TVR04_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1268850.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYFVTLLVGLGLAFAIA
                     YIWGFKDKSDQAAPATQAKSEPAQKASAAEELLSPVAGELIDLSEVADPVFSSGSMGQ
                     GIAIKPEGRILYSPVDGRVEAALETGHAYAIKSDKGAEILLHIGIDTVSMAGDGFEAF
                     VKVGQTVKAGDALGSFDIAKIRQAGLDATTMLLVTNSADVHAVQVLAQGKVAVGSPVI
                     LVK"
     gene            4899..6338
                     /locus_tag="TVR04_000128"
     CDS             4899..6338
                     /locus_tag="TVR04_000128"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1268851.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKYEQVLIDKPDD
                     VTEHFRDPQIFTYQDQLYAIIGAQNLQNQGIIKLYKANNNDVTNWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRGKLLEGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPDLSKLRDKAQPFQNKKNSSNCYELALTVEAQQAAELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGVKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEEQSGIELLKGQVSGYYYEMRY"
     gene            6343..7308
                     /locus_tag="TVR04_000129"
     CDS             6343..7308
                     /locus_tag="TVR04_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1268852.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPNIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKSADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGASL"
     gene            complement(7666..8166)
                     /locus_tag="TVR04_000130"
     CDS             complement(7666..8166)
                     /locus_tag="TVR04_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268853.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDTWHENCGWTYKNMGDIGYRYSITERVIKK
                     YDSNTDNGIIVATGHKGATIDGDGLIVPLKGKRKYSVTEDHDYTITITNLSDKPVAFR
                     AIVADR"
     gene            complement(8163..9117)
                     /locus_tag="TVR04_000131"
                     /pseudo
     CDS             complement(8163..9117)
                     /locus_tag="TVR04_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9108..9467)
                     /locus_tag="TVR04_000132"
     CDS             complement(9108..9467)
                     /locus_tag="TVR04_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268854.1"
                     /translation="MIKEESEDKFLALTQQINQLEWLEEDLLSMKRQHEQAVSELQAD
                     CRHLSFALESLLNHMPEDYAGKYAEQEANDHLLRQMDRYVDEHLDHVSTYIMGVRRQL
                     ERDQEKLIGERSRLRWE"
     gene            complement(9464..9745)
                     /locus_tag="TVR04_000133"
     CDS             complement(9464..9745)
                     /locus_tag="TVR04_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1268855.1"
                     /translation="MSDNITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEVTRWGNQS"
     gene            complement(9944..10396)
                     /gene="nusB"
                     /locus_tag="TVR04_000134"
     CDS             complement(9944..10396)
                     /gene="nusB"
                     /locus_tag="TVR04_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1268856.1"
                     /translation="MTKRFQHSRRDLRERAFQALFTMEMGGDFLLASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTGWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTD"
     gene            complement(10389..10778)
                     /locus_tag="TVR04_000135"
     CDS             complement(10389..10778)
                     /locus_tag="TVR04_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1268857.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            complement(10821..11378)
                     /gene="efp"
                     /locus_tag="TVR04_000136"
     CDS             complement(10821..11378)
                     /gene="efp"
                     /locus_tag="TVR04_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1268858.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            complement(11472..11933)
                     /locus_tag="TVR04_000137"
     CDS             complement(11472..11933)
                     /locus_tag="TVR04_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1268859.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVGYVQHDVPQIILGGAVEP"
     gene            complement(11976..13052)
                     /locus_tag="TVR04_000138"
     CDS             complement(11976..13052)
                     /locus_tag="TVR04_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1268860.1"
                     /translation="MSSFLAQRLNNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRIFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFYQHLQAALAGVSLLPQSGFVEGLRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQL
                     IAEAGYGSYFTHGIGHGIGLDIHEDPFFAKTDQRILAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(13342..16164)
                     /gene="uvrA"
                     /locus_tag="TVR04_000139"
     CDS             complement(13342..16164)
                     /gene="uvrA"
                     /locus_tag="TVR04_000139"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1268861.1"
                     /translation="MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETSSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEHGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKSGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVAAGTPEEVAAVEESYTGQYLKLKL"
     gene            16360..17304
                     /locus_tag="TVR04_000140"
     CDS             16360..17304
                     /locus_tag="TVR04_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1268862.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLAALLSTFVVIYFIRKKWF"
     gene            17563..18213
                     /locus_tag="TVR04_000141"
     CDS             17563..18213
                     /locus_tag="TVR04_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEL1268863.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNATVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYAATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMTPQR"
     gene            complement(18472..18711)
                     /locus_tag="TVR04_000142"
     CDS             complement(18472..18711)
                     /locus_tag="TVR04_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1268864.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(18870..19358)
                     /locus_tag="TVR04_000143"
     CDS             complement(18870..19358)
                     /locus_tag="TVR04_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1268865.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDESPFGGSNPMDISDDDL
                     PF"
     gene            complement(19377..19667)
                     /locus_tag="TVR04_000144"
     CDS             complement(19377..19667)
                     /locus_tag="TVR04_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1268866.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            complement(20730..20928)
                     /locus_tag="TVR04_000145"
                     /pseudo
     CDS             complement(20730..20928)
                     /locus_tag="TVR04_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21044..22192
                     /gene="mutY"
                     /locus_tag="TVR04_000146"
     CDS             21044..22192
                     /gene="mutY"
                     /locus_tag="TVR04_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1268867.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEIDYDIGDPKNRKIFQAVMEVLIDPDRPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSQGRLLLEKNTQGRLLGGFWSFP
                     LIETDFVSQQLTLFEDKPVVLETMSQTALFEERYGLVPDWSQVAFPQVKHTFSHQKWT
                     IELCEGLVDQAPLPSDRELAWVTLEDMTAYPMATPQKKMLEAYLGKRS"
     gene            22470..22754
                     /locus_tag="TVR04_000147"
     CDS             22470..22754
                     /locus_tag="TVR04_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268868.1"
                     /translation="MKLTKTLCLVAATVTLALAPINTSTGQINTVLAMQQTKQNNYPK
                     NCKKIDSQYFECPDGKLYYNGYDPYSFSAWVGRFFYAFYSVWSTLNGIFK"
     gene            22972..23859
                     /locus_tag="TVR04_000148"
     CDS             22972..23859
                     /locus_tag="TVR04_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1268869.1"
                     /translation="MNKKSARRKRNDIIAKLAMTSALTLGVGAAATMTGQTEAKAEVL
                     YMENLDMRDKAAVEKFANELKELVKKKESDHNLAWRKLSLILNGYKNFTQKIETELQA
                     SQQKVQELNELISKEKEQLEALKKELETEKAKEAEDIAKLQKEITEKGETISNLQGQL
                     EAFGQKVKELEAEKAALQEKLAMQEQAHAEEKAKLQKEIEDLKAQLEKLKHCQDTPKP
                     EPKPEPKPEPKPEPKPEPKPEAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAA
                     IAIMIAAGTIAIPKRKEED"
     gene            complement(24105..24419)
                     /gene="trxA"
                     /locus_tag="TVR04_000149"
     CDS             complement(24105..24419)
                     /gene="trxA"
                     /locus_tag="TVR04_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1268870.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            24599..25918
                     /locus_tag="TVR04_000150"
     CDS             24599..25918
                     /locus_tag="TVR04_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1268871.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQEQILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEFANLYASLGSKVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGVYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETSEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(26262..28598)
                     /locus_tag="TVR04_000151"
     CDS             complement(26262..28598)
                     /locus_tag="TVR04_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1268872.1"
                     /translation="MEKKILEQLEFDKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQADERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILKQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKQAKK
                     WRAPRVGDDIIVTAYGQRGILLAQLKDKRWEAQVGLIKLTLKEEEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(28671..29216)
                     /locus_tag="TVR04_000152"
     CDS             complement(28671..29216)
                     /locus_tag="TVR04_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1268873.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALMSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGATTLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVLVSILFLSMALTILATIPMPFIQGLLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(29216..29527)
                     /locus_tag="TVR04_000153"
     CDS             complement(29216..29527)
                     /locus_tag="TVR04_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268874.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            29645..30553
                     /locus_tag="TVR04_000154"
     CDS             29645..30553
                     /locus_tag="TVR04_000154"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1268875.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNASPYVRLAAKKDGVTLM
                     LYSSGKLVLQGRQAAGLAQELGLQETAADQRPAPSSAQDMPLIGSDEVGNGSYFGGIA
                     VVASFVRPEDHALLRQLGVDDSKNLSDMSIVQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KNKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFCNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQVLAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            30578..31177
                     /gene="lepB"
                     /locus_tag="TVR04_000155"
     CDS             30578..31177
                     /gene="lepB"
                     /locus_tag="TVR04_000155"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1268876.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            31390..33798
                     /locus_tag="TVR04_000156"
     CDS             31390..33798
                     /locus_tag="TVR04_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1268877.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPSSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDDILKNPSRLNEISGLSKANREAFVAKLKANYGTEQVIAALAELG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKMADSLAEQLGIESDSPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEEGIQKHLTRLLQQPLTKELSQDTIDQDIQAIQEELAIAYDEI
                     QKQTISQALTSKVFILTGGPGTGKTTVIRGILQAYASLHQIDLKKKDIPIILAAPTGR
                     AARRMNEVTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AISSNTQLIIVGDSDQLPSVGPGQVLADLLRVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLADQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIVIDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPYNFLTIDPMIGLTEDDMLTFFKKK
                     NIIY"
     gene            33886..34371
                     /locus_tag="TVR04_000157"
     CDS             33886..34371
                     /locus_tag="TVR04_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268878.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDKPQSIE
                     E"
     gene            complement(34514..35617)
                     /gene="dinB"
                     /locus_tag="TVR04_000158"
     CDS             complement(34514..35617)
                     /gene="dinB"
                     /locus_tag="TVR04_000158"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1268879.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKD
                     PRESGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTSNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPQGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRIRKSISSERTYAKLLYQEADIKAEL
                     SKNASRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            35826..38150
                     /gene="pflB"
                     /locus_tag="TVR04_000159"
     CDS             35826..38150
                     /gene="pflB"
                     /locus_tag="TVR04_000159"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1268880.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKIIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            complement(38234..39489)
                     /locus_tag="TVR04_000160"
                     /pseudo
     CDS             complement(38234..39489)
                     /locus_tag="TVR04_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057303.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            39875..40153
                     /locus_tag="TVR04_000161"
     CDS             39875..40153
                     /locus_tag="TVR04_000161"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268881.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASENHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENYKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(40317..41258)
                     /locus_tag="TVR04_000162"
     CDS             complement(40317..41258)
                     /locus_tag="TVR04_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1268882.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSDALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGKAAGSAGLFSTLRDL
                     ELFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIYRAFDRNSPR"
     gene            complement(41255..42010)
                     /locus_tag="TVR04_000163"
     CDS             complement(41255..42010)
                     /locus_tag="TVR04_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1268883.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRAVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIAPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(42502..43350)
                     /locus_tag="TVR04_000164"
     CDS             complement(42502..43350)
                     /locus_tag="TVR04_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1268884.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGAKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVVAVAAF
                     KFLYIK"
     gene            complement(43452..43904)
                     /locus_tag="TVR04_000165"
     CDS             complement(43452..43904)
                     /locus_tag="TVR04_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1268885.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLSYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(43924..45123)
                     /locus_tag="TVR04_000166"
     CDS             complement(43924..45123)
                     /locus_tag="TVR04_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1268886.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVLGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYL
                     VRLLNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRLIIVLCSVLIAVVVAGAFAFPVTNISLNSEQLAKTKSWTVDSFIEQKALFITL
                     IAFLMGIAYASVLGFQKLYTTEIHLTTVGAYFFVVYALIITITRPAMGRLMDLKGNKW
                     VLYPSYLFLALGLFLLGSVTSSVPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFRQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            45292..45951
                     /locus_tag="TVR04_000167"
     CDS             45292..45951
                     /locus_tag="TVR04_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1268887.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQIQDQHIIITNLEKLKDNIV
                     F"
     gene            45971..48256
                     /locus_tag="TVR04_000168"
     CDS             45971..48256
                     /locus_tag="TVR04_000168"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1268888.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKESFAIFLRKL
                     FFHFQDTDYPLSHMIATKELDLLSFLASDEALTKEVFDLVALQVLGFIPAVDFTDTQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADHIKCEVVYTHGLQDWNVKPRQVYNIFNALPDGLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGEDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILSAQLLDYGKKKRFGDLPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSNLLTIEDIPNDQWISITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(48362..48754)
                     /locus_tag="TVR04_000169"
     CDS             complement(48362..48754)
                     /locus_tag="TVR04_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1268889.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTYSNIQANGKIEVAYVNREQLRGYRFVGHAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(48943..49164)
                     /locus_tag="TVR04_000170"
     CDS             complement(48943..49164)
                     /locus_tag="TVR04_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1268890.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFLGDDSDFMK"
     gene            49343..49717
                     /locus_tag="TVR04_000171"
     CDS             49343..49717
                     /locus_tag="TVR04_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1268891.1"
                     /translation="MSEKKTFFATNLKYLRLKRNMEQLELANLLGRKSSSSISEWERG
                     KYTPKSGLLSDIAAIFNVSLTDLMEKDLTLENKGVTYQLPQRDLVMISEQLSENNYNK
                     WLDFGQDLLSHQDKEENHKPSK"
     gene            complement(49975..50757)
                     /locus_tag="TVR04_000172"
     CDS             complement(49975..50757)
                     /locus_tag="TVR04_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1268892.1"
                     /translation="MSAYKALLLVTLKIKISQWQYSLANQRTVRIEEESLDIIKRHRA
                     AVLVMLYIIAVYLYRQVSNVIELPPLLNTFLFYGRHLLIFALGICWLYRADYQRDWQQ
                     FSTKWVKNTLWVLVIFAVLYAANILLSSLPLPEGSNAAVLANRYNASEGFETVIFILV
                     VSIIGPFNEELIFRKILIGEGQSGTGMLLARLLGSSLLFGLVHIYSFSKLSSIVVYGG
                     LGLLLGLVYVWKKNIYFSTAAHILNNGIGYVFILLELLGVLR"
     gene            complement(51115..52623)
                     /locus_tag="TVR04_000173"
     CDS             complement(51115..52623)
                     /locus_tag="TVR04_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1268893.1"
                     /translation="MLEKYLEPVINHQALLLTILLAKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPYYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRREFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSTLLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKPLANRIELMINSWAERVPGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVVQQVSPCVAKVYRFNILSEAELPCKTDFDLIVTTAEMT
                     AFIKERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILSR"
     gene            52869..54602
                     /locus_tag="TVR04_000174"
     CDS             52869..54602
                     /locus_tag="TVR04_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1268894.1"
                     /translation="MERRELKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQYYGWT
                     DINSRAESPFFLYVTPKNNPKRELKNAYVVYCFNRDKKWPANWEEVNNYRKPNELDLP
                     IYDKRIGTNQLFIKEASHPRLKIDMEKSLVAILSKGFPNNSTELISKYKLDNNSARVV
                     TQLAIWYFSDSVNDPESVLRQRLKENESQALKYLISVGEHPQLSQAEQKQTLDIYVYN
                     SGGYYGKDYQNLLGSSLVPKEEKPSSESVTQSNLILLEQNNHSDIISGGSGNTETEED
                     TPHLMGIGGGLAGESGETAPKPGETGGHSPIIEENYGGTEEFHGNSEIISETEDTNPG
                     IILGGSGNVETHEDTRNPHLMGIGGGLAGESGETTPKPGETGGHGPIIETTEDTQHGI
                     SGNSGGAIESEDTKKPEVLIGGQGQTIETTEDTQHGMSGNSGGAVESEDTKKPEILIG
                     GQGQIIDFSENTQSGMSGQSGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSG
                     GTTIVEDTKKPTPKPKPAPAPIVNDEKPNKGTQLPQTSDMKQLTLSIIGTMSMLLVLC
                     LSLFKRPSKKD"
     gene            complement(54973..56019)
                     /locus_tag="TVR04_000175"
     CDS             complement(54973..56019)
                     /locus_tag="TVR04_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1268895.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQENRS
                     VHIEVAKEVVKINSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVETSRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGA"
     gene            complement(56021..56707)
                     /locus_tag="TVR04_000176"
     CDS             complement(56021..56707)
                     /locus_tag="TVR04_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1268896.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIITDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYERVWEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKT
                     VWGLGYKLEG"
     gene            complement(56846..57433)
                     /locus_tag="TVR04_000177"
     CDS             complement(56846..57433)
                     /locus_tag="TVR04_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268897.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQQLELPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPVAPQLTDQDAQQLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLELPDYVRGSIYGILNQNSSITYPRDY"
     gene            complement(57999..58403)
                     /locus_tag="TVR04_000178"
     CDS             complement(57999..58403)
                     /locus_tag="TVR04_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000878125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1268898.1"
                     /translation="MKYTYLALFEADRENGGYTITFPDFPGAISEANTLNEAIYNARE
                     VLEIYAIMFEDEGKKFPKPSSFKALASNLASDEDVIQAISVDTELVRERERSKIVNKT
                     VTLPSWLVEVGKENKINFSQLLQKAIREELQV"
     gene            complement(58457..58645)
                     /locus_tag="TVR04_000179"
     CDS             complement(58457..58645)
                     /locus_tag="TVR04_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1268899.1"
                     /translation="MTTRRELEKLAKEKGFRPTDKGKGSHVLWEHEDGRTILISNPKQ
                     KDYKPKTLQSVLKVLNRK"
BASE COUNT        17299 a        13770 c        11547 g        16137 t
ORIGIN      
        1 tgaactaatt tatttgtcgt tttgggattt cttgcagaat cattaaagaa acgccagtgc
       61 ttaacaatac ctgaattttt taatttgaaa ataatagact ttttcgaatc ccagcctaaa
      121 aaaatgttat cagttggact tcccagttga ccatcaaaca ctttttttgc atttgttgga
      181 tctgcgtcac caccaatcac agttgctccc tctgataggt taaccatcat ggttttttct
      241 tcaccaacga caaccttagc ctcatgcaca ggcttagtgc tattagtagg gctaaagaat
      301 tcaaccttgt aggtttcctc cttgctagtg gataagtcct tgtgatcagt gacacctaag
      361 gttgagtcag tcaccttgat cttatagtcc ttgtaggtca ctgcaaaggc tttgtaatca
      421 tagcttgaat caacaaaacg gtgacctgct atttcctgct cctgataagc cttatagtca
      481 gcttcgctat tgattagcgt gccctgattg gtaactgttc caaataaaag cttagcctgc
      541 aaatcaattg tatcatttgc tactggtaac tgaaggctct tagtgccata agtatcagga
      601 taaagaccag taggcttttg atgatcaaat acaaacgtct tttcgctaac accaccatgc
      661 ttagtcactg ttgccagcat ggtatcaaaa atctgacgat tttccgtacc agctgctaag
      721 tccagcttat tcttagaaag atctaccttt tcaagagagg ttaggctagc tgcgtcaatt
      781 ccagccaagg tctcacgctc aaagccagca agttttaatt ccttcaagcc tgttaaccca
      841 gaaatggtta atgctacttg tggaatagcc ttagcctctt ctttcctatc atcattttta
      901 taggtttcta gaccgctgac tagcgtatcc tttgttggct tagcatttgc aggtaggact
      961 aagctatcca gctttgtgat ttgtgataga ccaattagct ctagcttagc tagtttttta
     1021 agcttattta gaccttctaa gctttgaata gctggattat ctaatcgcaa tgtgccattg
     1081 aaccgctcta aatcccctct tctgcttcca acctgtgcaa taactgcttc tcgcaaagcc
     1141 ttgtctggaa aatctgtttc atcaatcagc tcataggatt tgtcattttc cataaccttc
     1201 ttcaaggcct tagaaacctt ataatctgat ttaacaatct tatctaaatc aggggtttta
     1261 ggcccattct ttttaggatg cgctacacca tcacgatcta taccgtaaga aaaaattccc
     1321 cctttgacac cacctgtctt aggctgccat tttgcataac gctcagcacg tgtcccctta
     1381 atttcgctac caatatttgg attagtatca tcttctacat tgacatcgta ccacagattt
     1441 ccactatttg ccttttcttc atagaaagaa aaaccaacca tgtactgctc aggacgaatg
     1501 tatttgctat acgattccca gcgctcttcc atagtgtcta cagccttatg gttagcattg
     1561 tcaaagccgc ccttctcacc ctgggtgcca taaacctgca caagcagcaa atcaatatat
     1621 ggcgcaccgc gctcaatcaa tgggttcttg tcagccatgt aggtgctatc cataatgaac
     1681 aaacgtgact tgtcagcacc ctttggccca ataagcttac caatttcttc aaaaacctga
     1741 atggagcgtt ctatcccttc tttactttcc tctttattta cttttggaat gctatctcgc
     1801 tcaatatcaa catctaaacc atcaagatta tatttataga catattcatc tacaatagcc
     1861 ttggccaaag ctttatttcc ctctggagta tttgggtatt tttgcgcatc ttctgcaata
     1921 ccactatgat caccacctgc aaggaaccgc caaggaatcg tacgaatcac gcgcgtgccc
     1981 tgcttgttca gcgttggcac atgcttggtt gccaattcct gccaaaaaag gctgtaatcc
     2041 ttggtccaat catggaaaac aaaggctaag tcaacctcct tgggcaattc tcccatagaa
     2101 ttaaccttat ccttttcagc tgggtctgat gttttatcat gccaggtcct aaaataacca
     2161 ccataaagag gcccctttaa aggcttcatt ggtatttttt cgggaacctt catttctgca
     2221 agtgtttttg cctgcttgtc tgcctgctgt gccttagaca caatttcttt tagcttttca
     2281 ggctgcgcct tttctacctt tgataactcc tccttaaatt cttttttact gttttccgac
     2341 agataatgta gggcatcaat agcagagact gatgggctag tttgcacaag cttatcctcc
     2401 gccttgaccc ttatgagtga atcatgttgg gcagctaata tagccaccat taacgctgca
     2461 gcacaaacac atttcagtgt tttcttgact aacacctgtt tttccattgg gacactcctt
     2521 tattttgata ccaaagaatg gccaaatctt tgcttaacca aaaatgtaag cgcattctct
     2581 gtgttcatct aaagtatagt agacctcatg atcaaaagca atgcacaaag tataggtaaa
     2641 ataaaagaaa cttaaggtct tttaatttct gtaatttcat ggcgaatatt ttaatcttac
     2701 atgtaaaaag agctgaaatc atcaactctt ttcaagttat tttacaagga tcactggact
     2761 gccgacagcc accttaccct gtgccagcac ttgaacggca tgaacatctg cactgttggt
     2821 gacaagcagc atggttgtag cgtcaaggcc tgcctgccta atctttgcaa tatcaaagct
     2881 cccaagggca tcaccagcct tgactgtctg accaacctta acaaaggctt caaagccatc
     2941 acccgccatt gaaacagtgt caataccaat atgcagtagg atttctgctc ccttatctga
     3001 tttgatggcg taagcatgac ctgtctcaag ggcagcctct accctgccat ctaccggtga
     3061 gtagagaata cgcccttcag gcttgatggc aatgccttgg cccatgcttc ctgacgaaaa
     3121 gacaggatca gcaacttctg acaaatcaat cagctctcct gccactggac taagcagctc
     3181 ctcagcagca gaggcttttt gcgcaggctc tgattttgct tgggtagccg gtgctgcctg
     3241 gtcactcttg tccttgaatc cccaaatata ggcaatcgca aaggctaaac caagcccaac
     3301 cagcagcgtc acaaaatact gtagcagctg accattaaga tacagcagtg caccaggcaa
     3361 aacagtaatc ccaaagccgg taccagcaat gccaagaatc cctgcaaccc agcctccagc
     3421 tgcgcccccg ataagtcctg aaacaaatac ctttggatag cggagattaa caccaaagat
     3481 agccggctca gtaatcccta aaagagctga cagggctgat ggaaaggcta aaccctttaa
     3541 ttttgcagat ttggttttaa cagcaactgc tagggttgcc cctgcttgag cggctgtagc
     3601 agctgtcaaa taagcgttaa agggatcctt tcctgtattg gcaactagct gtgcctccaa
     3661 gaaattgaaa atatgatgga tacctgtcac aacaatcagc tgctgaacac ccccaataac
     3721 aaggccggca ataccaaaag gcagacctaa aactgcttgt gtccctgcaa gaacaaggtt
     3781 ttccaaggag tgaaagatag gcccaatcac aaagagtccc aaggcactca tgatagcaaa
     3841 ggtcaaaaac ggcgttgcca ataaatcaag cgcatcaggc acccgcttat gcagccactt
     3901 ttccagcttg gcaccaacca gaccaacaaa gaaggctggc aataccgtac cttgataacc
     3961 aacaactgga acaaaaccaa agaaggttaa gggcttaaca tcacctcctg aggctaccac
     4021 ccaagcattt ggcaattcat tggagacgag catcaagcca aggacaatcc caatgatagg
     4081 gttgccacca aataccctaa aggctgacca agcaaccaag gccggcaggt agacaaaggc
     4141 cgtatctgtt aagatccgag tgtacatgag gaaattgtcg ccatagtcat gaatgccaaa
     4201 gaactccata acagctggct gcgtcaagag acctcgtaca cccataaaca gcccagtcgc
     4261 cacaatagca ggaataatcg gaacaaagac atcaccaaag gtacgaatag cccgctgaaa
     4321 ggcatttcca gacttgacca cttgctcctt ttgctcacct gccaaagcag ctggaagccc
     4381 tagagccaca acctcatcat aaatgctatt aaccgtaccc gtcccaaaaa tcagctgata
     4441 ttggcctgag ttgaaaaaag cacccttaac cttatcaata gcctctgctt tttctttatt
     4501 gatcttaccc tcgtcatgaa ccataacacg caaccgcgtc gcacaatgag ccacacttct
     4561 gacattttca cgaccgccta aggcctcgat aacctctttt gcaatctgat gattatccat
     4621 accgatagca tctccttttt tgtctattat agtctatcga aatagctttt cttgagccta
     4681 gccaacatca actgacctat cctgctggct agctcaacat gacccttcaa tctactattg
     4741 tgaatccgct tcacttcttg ctatcatttt aacacgaata tttattatgt caagcgtttg
     4801 acatatattt tgtttaaaat aattaaaaaa gttgattttt agagagaaaa cgtttatcat
     4861 atgaataaaa taatgaccaa tacctaagga gacctcacat ggatttacca agatctattc
     4921 gctaccgacc atatcaagaa tggagcaagg aagcctatca agcaatccaa caaaaggtgg
     4981 cccagtcttt atggcgcagc catttccata tagaagctcg tacaggtctc ctcaatgacc
     5041 caaatggctt ttcttatttt gctggcagct ttcagctttt ctatcaaaat tggccctttg
     5101 gagcagctca tggtctaaag caatgggtac acaccacatc aactgacttg gtgcatttta
     5161 cagaaaccaa aactcggttg ctgccggatc atcaaaatga tagtcatggc gcttattccg
     5221 gctctgctta tcctattggt gacaaactct ttttatgcta tacaggaaat gtccgcagca
     5281 aggattgggt acgccaccca ctacaaattg gtgcctggat ggaccaatca ggccacatca
     5341 caaaatatga gcaggtgctt attgacaagc cagatgatgt cacagagcat tttcgtgacc
     5401 cccagatctt tacctaccaa gatcagcttt atgccatcat tggtgcgcaa aacctgcaaa
     5461 accaaggtat aatcaagctc tacaaggcta acaacaatga tgtcaccaac tggcagtttg
     5521 ttgctgactt agactttgat gactcaggca ctgcatacat gatcgaatgc cctaacctgg
     5581 ttttcatcga agataagcct gtgcttatct tctgtcctca ggggcttgcc aaatcagagc
     5641 ttgattacca aaacatttat cccaatacct ataaggtatt tcagaccttt gatcctaaaa
     5701 gaggcaagct ccttgaggga ggtccaatcc aaaaccttga ttttggattt gaagcttatg
     5761 cgacacaggc ctttaatagc cctgatggta gggtgctggc agtttcttgg attggcctgc
     5821 cggacatcga ctacccaacc gataaatatg cctaccaggg agcgcttagt ctagtcaagg
     5881 aattacgact caaaaatgga aggctacacc aagcaccagt ccctgatctc agtaagctac
     5941 gagacaaagc ccagcccttt cagaacaaaa aaaacagctc aaactgctat gagctggctt
     6001 tgaccgttga agcacagcaa gcagcagagc ttttgctctt tgccgataca cagcacaagg
     6061 ggctgaaact gaccgttgac acctgcaaag gacagctaac aattgatcgc agcaaggcag
     6121 gcgcccagta tgcccaagaa tttggagtaa agcggtcttg ccaaattcct gtcaatcgtg
     6181 ctacacttaa tatctacgta gacaagtcta ttctagagat ttttgtcaat caaggcgaag
     6241 cagtcctcac gagtcgtgtc tttcccaatg aggagcagtc tggcattgag ctgctaaagg
     6301 gccaggtgag tggctactat tatgaaatga ggtactagac aagtggtcgc aaagttaaca
     6361 gatgttgcag cattagccgg tgttagccca acaacagtct cacgtgtgat taacaaaaag
     6421 ggctatctgt cccagaaaac cattgataag gttaacaaag ccatgcgaga gcttggctac
     6481 aagccaaata acctcgcacg aagcctgcag ggcaaatccc ctcagctcat tgggctgatc
     6541 tttcctaaca ttagtaatat tttttacgcg gaattgattg agcatttaga aatcgagctc
     6601 ttcaagcaag gctataaagc catcatctgc aacagtgaaa acaacccgat caaagaacga
     6661 gattatctag aaatgctggc tgccaatcag gttgatggca ttatctcatc aagccataac
     6721 ctaggtattg atgattatga gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc
     6781 gctcccaata tccccatcat atcctctgat aattttgaag gaggaaaatt ggccgcaaaa
     6841 accctgcaaa agcatggctg ccaaaaaatg atcatgatta caggaaatga tcattctgac
     6901 tctccaacag gtcttagaca gttaggcttt aattaccagc tcaaaaaaag tgctgatatt
     6961 ataaaactac caaatgatct ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg
     7021 gcgacaagaa ggcctgacgg catttttgct tctgatgatt tgacagctat cctcatcatg
     7081 aaggttgctg gccagcttgg catagcaatt ccagataacc tgaagcttat cggctatgac
     7141 ggtacggctt ttattgagca ttatttccca cagctcacca ccatcaagca gccgatcaag
     7201 gaaattgcca gcttaaccgt agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc
     7261 aaagattatg ttctaccaat tactctcctg cctggagcaa gcctctaaga gcaatagctc
     7321 ttcttctgtg attggcggct ttcccctagc ttctccctta cttggggcac taaagtaaaa
     7381 accaaagcac gaggtgggaa accctagacc accaggataa accctgataa gtccctcaga
     7441 tgggtcttac cacctaacac acaagaaaag cttcctcaag ctgtccttta cccccttttc
     7501 ctaacaatgc caccaaaaac acatataaca gcaattgaca gactccccct atagcaaaca
     7561 gtgacccaag aaaccatcac tagaagctat aaagggagct tttctatgcc taacaaaaat
     7621 ctaaaatcaa taacagaaaa acctaaagca gttcatgcgc acatactacc tatctgctac
     7681 tattgctcta aaagcaaccg gcttatcgga taggttggta atggtgatag tataatcatg
     7741 atcttctgtc acactatatt ttctcttccc cttcaaggga acgatgaggc catctccatc
     7801 aatagtagct cccttgtgtc cagtggctac gattatgcca ttatctgtat tggagtcgta
     7861 ttttttaata acacgctctg ttatagaata ccgatatcct atatctccca tattcttata
     7921 tgtccaacca caattttcgt gccatgtatc acgaccttct agcttcagta gcactttttc
     7981 gtcgctttct aggtataggt cagaggaata ttctatttgt tcatactttg gtctcaccgc
     8041 aagctctata ctctcatttg gccttagata ttcttttcct tgaaaaaaat agtaaagctc
     8101 atagcgtttg gagaagatga aaacacctac cagcaacatc attaataaca ggatttttcg
     8161 cttcattttg acttcttcct tttcacataa ccatctatac cagcttggat catttgagta
     8221 tcgccctcat tgtctccata atttcccttt ttaatactat tcagccactt atcaaaatcc
     8281 ttatcagaaa agacctgggc aatcccagct acctgtgaaa ggtagggagc attgacatta
     8341 accgataaga tatcatctcc catcttgttg acaatcaaac gaaaattaat acccgacgat
     8401 tgtaattttt tccctaggtc ttcctcaatt tcctttgcat atttattatt tttaaggtcc
     8461 cactctccat cataattgct tctcgccttc caatagtcat caaaggctgg cttattgaga
     8521 aaatagaggt aatcctcata ggcagccaca agtcgctctg atttttgtag cggcctttca
     8581 gagctgcttt tgatggcttt aatggtttga gtcagtatgt tatgataatg attttgagtg
     8641 tactttgaag cattgacagg gctaatctct tgattcctca ggctagtcac ccagctcata
     8701 tctaggccgg cagtcgagta gctgccgtcg ctgctcatga agacctgact gagctgtgtt
     8761 gcgccctgaa tggctaaccg caaaataact aagctgtccc taaagcagtc tgaggtttga
     8821 gttagaaacc attcaaggct ttccaatttg gtcgcaacct ctcgaatccc tatttccagc
     8881 tggtttttgg catggtatag cgtagaggta tcagaccaaa gggtgccata gtctccggtt
     8941 aaaagactac tggcctgctg tataggctgc tccctgtagc tctcccgaat ccagactagc
     9001 aatgagatgg tcgcaaccac ttgataacct gtccgttatc tcattggcta tttggatatt
     9061 gtttgtcata gcttgaatca aggcctttga ctctgctgca ctgtaggtta ctcccatcgt
     9121 aaacggctcc tttcaccgat aagcttttct tggtccctct ctagttgacg acggactccc
     9181 atgatatagg tcgacacgtg atccagatgc tcatcaacat agcgatccat ttgtctgagc
     9241 aaatggtcat tggcctcttg ctctgcgtac tttccagcat agtcctcagg catatggttc
     9301 aatagggact caagggcaaa agagaggtgc cgacagtctg cttggagctc cgagactgct
     9361 tgttcatgct gccgtttcat tgacaaaaga tcctcctcta gccactccag ctggttgatc
     9421 tgttgggtta gggcaagaaa tttgtcttca gattcttcct tgatcatgac tgattccccc
     9481 atcttgttac ttcctctagg tctcttttct ctaatttggc cgcaagctga ggaaatttat
     9541 tggcctgaat aaggactgcc tgactaaagt cgctgacagc ctgcagcagt tgattagaga
     9601 cctgacgtcc cttttccata cctgcaatac ccttggtcac actaaatgca acggactgtt
     9661 ggtgaaccct actggtgtct acgcctacca attcgctaat agcggcagag gcagccacag
     9721 ggcttgatgt gatgttatca ctcatacaat ctctccttta taacccttat gtctgtcatt
     9781 ataccacagg ataatagcca ttgtgcttat agctcttacc taaataacag caactgacga
     9841 atttttttgg gaattcattg acatagccaa ccagatgaga cgtttttgag cattcaaaaa
     9901 gccctatagg gctttagtaa cttaagaagc tttcaccagc ttgttagtct gtcactgcag
     9961 ctgactcatc agaaacaaac tgactgagta agccattaat aaacttagct gaggtatcat
    10021 cagaatattt tttagcaatt tcgatgattt catttagggc tacacgatct ggtgtctcct
    10081 caaacaaggt catctcaaag agcccaagac gcagcattgt cttgtctacc actgtcaagc
    10141 gctcaatgga ccagcccgtt ttaaggtttt tcttgataac ctcatcaagc tcagccttat
    10201 gatccataac gccattgaca agatttaaca gaaaaacagg aagctcagaa ggctgcttgt
    10261 catcagctgc ttccttgtca tagtcatagg caaactgtga ggcaagcagg aaatctcccc
    10321 ccatctccat agtaaataaa gcttgaaaag cacgctcacg caaatctctt ctcgaatgtt
    10381 gaaaacgctt agtcatccaa aaaatcctca tcaaacaatg atttcatttc tggctttggt
    10441 gtcttttcag gaacgatccc ctcaacatgg atattgacat aagaaatggt aacctcagcc
    10501 atgtcataaa ccgctgactt aacagccctt tgaatagcca ttgacaccgc aggaaccttt
    10561 acaccgtatt gcaggtaaac gtagatgtct gcattgactg ttccattttc ctctgtctga
    10621 aggtaaacgc ccttaccaag actagcttta ttaaaggtat ctgccatgtt tttattgtga
    10681 agcgagtgaa caccctcaac ctgcatcgta gcaattccag taataacctc aagaactcgt
    10741 ggcgaaataa caatttcacc gatattttca gttgtcatag catttccttt ctttctctta
    10801 gactaattcc gtaaagcgaa ttaagcacga gaaacgtaag taccctcagc agtattgatg
    10861 attagctttt gccctacctc aataaagtct ggaacgttta ccacaagtcc tgtttcaagg
    10921 gttgcaggct taccagagcc tgtgacagtt gctcccttga ttgatggctg ggtctctgta
    10981 acagtcaact caacagtggt cggtacctga accccgatca cttctgttcc ataaaactgg
    11041 attttcacgt cagagttttc aaggatatac aataactctt gctcaacatt ggctactgga
    11101 atctcatact ggtcataggt ttcagtattc ataaagtaag cagtatcgtc catcttgtaa
    11161 aggtattggg ctggcactgt ttcgataata gcctgttcaa acttttcgtc tggacgatag
    11221 gttgtgtcga atgtagagcc agtacgaaca tcacgcaatt tcatacgcat gatagtgttt
    11281 cccttacctg gcttatgatg gcttgcttca agtacgcgaa ttagctttcc ttctgcttca
    11341 aacgtcatac ctgctctaag cttgcttgct tcaatcattt gttattacct cttactaaaa
    11401 tagttatcgt cttattttac cacaaaagag ctgtaggctc aaatgtttta tgaccattat
    11461 tggccttggg cctaaggctc aacagcgcca cccaagataa tctgaggcac atcatgctga
    11521 acatagccaa cccctttttt atccattagc tcaatggcaa aagggtgggg acgataatgg
    11581 gatttatagg taattttgca aataccagcc tgaaggaggg ccttggtgca attgatacaa
    11641 ggaaagtgtg tgacataaat ctctgttcca gcagttgaaa tgccctcctt agcacattga
    11701 atcaaagcat tcatctctgc atgaacagtc ctgatacaat gcccctcttc catataatgg
    11761 ccggcttcgt tacagttatc agtcgctgat acgccaccgt tatagcctgt cgcaataatg
    11821 cgattgtcct tgactaggac cgcaccgaca aatgctcgat cgcaggtcga gcgcttagat
    11881 atcagctctg catttgccat aaaataatct tgccatgata gcctatctgt catttttgtc
    11941 tcctaattcc tcctagctca cagcagctaa caagcctacg ttaaaacaat caattccttt
    12001 ggtgccttgg ttaagacctg acagcctgtc tctgtgatga caagatcgtc ctcaatacgc
    12061 acgccgtatt tgccatctaa atagatacct ggctcatctg tcaccaccat accagcaaga
    12121 atcctttggt ctgtcttagc aaaaaatgga tcctcatgaa tatcaagtcc gatcccatga
    12181 ccaataccat gtgtgaaata actgccatat cctgcctcag caatcagctg acggggaata
    12241 gcatcaaact cacgataggt catgcctgca ctagcctttg caatcaaggc ttgattagct
    12301 gcaagaacca gctcataaat ctcacgctcc tggtctgtca cctgtccgat atgaatagtc
    12361 cttgtcatat cactgacata gtgctggtaa taacagccaa agtcaagcgt caaagtctcg
    12421 ccctgctgaa tgattttgtc tgtagcacga ccatgaggca tggcagagcg atagcctgag
    12481 gctgcaatgg tgtcaaagga aatgcctgag gcgccgtatt gacgcatgcg aaaatccaag
    12541 aaattagcca cctcaagctc acttgtctgc cccggcttaa taaagtccaa gacatcacag
    12601 aaggccttgt ctgaaatcga gcaggcttta gcaataatgt caatctcaga agcgtcctta
    12661 atcagacgca gtccttcaac aaagcctgat tgcggcagca agctcacccc agcaagggca
    12721 gcttggagat gctgataaaa agaaaaggat acctgatcct caaaggctag actgctaagc
    12781 ttgtccgcct gtaggattgc agcaatttca gccagaggtg tgcgactctc aatgatatca
    12841 aagccctcaa tgctagcctt agcaatcaag gtataacgcg aatctgtaat aaaaatacgc
    12901 cgctttggac tgataaagac cgtagccgag gtccctgaaa agcctgtcag gtaataaata
    12961 ttcgtcagat tagtaattaa aatagcctcc aagccctttt tttccagtaa tgcttggcaa
    13021 ttgtttaagc gctgtgctaa aaatgatgac atggtaatct cctttatcga caaaactatc
    13081 ttaagtttac catgatttca acgcttttaa aagcaggacc cattagagaa agccaacaaa
    13141 aaagcatttc tgacagtgga tcaaaaggct aatcagctta tccgccacca ccaaaaatac
    13201 cttttaaata tcaccccgca ctcccgcgaa gagagctact ggctatctat tatttaaatt
    13261 aaaatcaccc ctcatttcaa tccatgccct atcatcgttc atacgaagat cactctgtca
    13321 attgatttca ggcctgcaac tttacaattt cagcttcagg tactgccctg tgtagctttc
    13381 ctcaacagcg gcaacctctt caggagtccc agctgcaacc agttgacctc caccaacacc
    13441 gccttctgga ccaaggtcaa taatatgatc tgccgacttg atgacatcta aattgtgctc
    13501 aatcactaaa accgtattgc catcatcaac aaaacgctct aaaaccttca gtaatcgcgc
    13561 aatgtcatct gtatgcagcc ccgtcgttgg ctcatctaaa atatacaagc ttttaccagt
    13621 tgagcgcttg tgcagctcac tagccagctt catgcgctgg gcctcaccac ctgatagggt
    13681 tgttgctggc tgccctagag taacatagcc aagcccaacg tccttaatcg tctgaatttt
    13741 acgagcaatc tttggaatcg ctgagaaaaa taccagagca tcatctaccg tcatatccaa
    13801 aatttcagca atgtttttac ccttataatg gacctccagc gtctctgaat tatagcgtct
    13861 gccatgacaa acatcacatg gaacgtagac atctggcaaa aaatgcatct caatcttgat
    13921 aataccatct ccagagcagg cctcacagcg cccacctttt acattaaagg agaagcgccc
    13981 ttttttgtag ccacgaatct tggcttcatt agtctgggca aaaagctctc gaatatcatc
    14041 aaacacaccg gtataggtag caggattaga gcgcggtgtc cgcccaattg ggctttgatc
    14101 aatatcaatc aaccgttcca aatggtcaat gccagtgata gacctatgct tgcctgactt
    14161 ttcagagtta cggtttagcc tttgagccac tgcttttttg agaatgctat taaccagcgt
    14221 tgattttcct gagccagaga ccccagtcac tgcaataaat ttccccagag gaaacctcac
    14281 atcaagattc tgcagattgt tttgggctgc tcccttgata tcaatatagc gaccattgcc
    14341 agcacgtcgc tctagaggaa caggtattga tttgcgtcca gataggtatt gaccagtgat
    14401 agacctttta tgccgagcga cctgttgagg cgttccagag gcaacaatct gcccgccaaa
    14461 atccccagca ccaggtccca catcaatcag ccaatccgcc tgcatcatgg tatcctcatc
    14521 gtgctcaacc acaatcaagg tatttcccaa gtcacgcatt tttttcaagc tatcaatcaa
    14581 gcgatcgtta tctcgctggt gcagaccaat agaaggctcg tccaaaacat aaaggacgcc
    14641 tgacagatta gagccaattt gcgttgccaa acggatacgc tgactctctc caccagacaa
    14701 ggtgcctgcc gagcgagaca aggtcagata attcagaccg acattattca aaaaggtcag
    14761 ccgatcatga atttccttga taattggctt tgcaatggtg ctttcgttgt ctgacagctc
    14821 aagccgatct agcagctgca gatggtctgc aatagatagc tctgacacct gaccgatcgt
    14881 caagccatgc tcaccaccaa cacgcacaca cagggcttga tcattgaggc gatagccatg
    14941 acagctcgca caggtcaatt cgttcatata gcctcgcatg acattgcggg tgtaatcact
    15001 gctggtttcg tgataacggc ggttaatatt tgtcacaacc ccttcaaagg gaatatcaat
    15061 gctgcgctcg ccaccaaaat cattgacata gtgaaaatgg aactcctgat cacctgagcc
    15121 atacaggatc agctcctttt cctgctcgct caattgctca aagggcttgt ccatatcaac
    15181 gccaaagctc tgcattgcct gctcaagcat ggttgggtaa taatttgacg agataggatt
    15241 ccaaggagca agagccccct ctctcaaggt cttactagga tcaggaacaa ctagatctaa
    15301 atccacctcc agcttgatcc ctaagccatc acaggtagga caagagccaa agggcgcgtt
    15361 aaatgaaaaa agacgaggct ctagctctgg cactgtaaaa ccacatacag gacaggaata
    15421 atactctgaa aacagcagct cattgccgtc catcgtatca atcatcagat aaccatctcc
    15481 caggcgaagc gcagcctcta tcgaatcaaa aagacgactg cggatcccgt ccttattgac
    15541 caagcgatca atgacgacct cgatattgtg cattttgctt ttggataatg ctggtacctc
    15601 tgacacatca aaaatctctc cgtcaacacg cacgcgcaca taaccgtcct tttgaatttt
    15661 ttcaaacact gtcttgtgct gacccttttt acgacggaca agaggcgcca aaatctgcat
    15721 acgcgtccgc tcaggcaact ctagcacctg ctcaacaatc tgctccactg aagaagccgt
    15781 aatagcccca tgcccattga tacaataggg agtccccaca cgcgcataaa gaagcctgag
    15841 gtaatcattg atttctgtca ccgtaccaac ggttgatcta ggattcttgc tggttgtttt
    15901 ttggtcaata gaaatagcag gactaagccc gtctatagag tccacatcag gcttttccat
    15961 gttgcctaaa aattgcctag cataggctga caaactctcc acataacgcc tttgtccctc
    16021 agcataaatg gtatcaaaag caaggctaga ttttccagac cctgataagc ctgtcaccac
    16081 aacgagctta tcacgtggaa tctccacatc aatatttttt aaattatggg cacgtgcccc
    16141 atgaataatc aatttatctt gcatgctctt gtgcccttag gcaccctcct catcgagatt
    16201 tattccatta taacaaaaat ttctaataat cagttgcccc aaacaccatg aatttgtagt
    16261 ataatagaca ggtattgagt gtttttcaaa aaggcttcgt ctacctgatg acaagaagct
    16321 cactctaata ctgactaatc acaaaaagga gggcttgtca tgaaacaaat gtttctttca
    16381 tcggcaattg aattcaaaga aatcgaaaca ttcgagccag gtgcttggat caaattggtc
    16441 aacccctccc aggaagagtc aatcgccatt gccgatcaat ttaacattga tatttctgac
    16501 ctgcgtgccc ctttggacgt tgaagaaacc tcacgtattg ctgtcgagga cgactacacc
    16561 ttgattatcg ttgacgttcc ggtctatgag gagcgcaaca acaaaagcta ctatgtgacc
    16621 atgcctttgg gaattatcgt cactgaaagc gcggtaatca ccacctgcct gcatgacatg
    16681 acactttttg atcagtttca taagcgtaag gttaaaaact tttatacctt tatgaagaca
    16741 cgttttgtct ttcaaattct ctatcgcaat gccgagcttt tcctaaccgc actgagaacg
    16801 attgaccgac aaagcgagcg cttggaggcc cagcttgagg cagcaacccg caacgaagaa
    16861 ttaattgaca tgatggagct tgaaaaatcc atcgtctacc taaaggcctc cctcaagttc
    16921 aacgagcgca ttgtcaagaa attatccagc tcaacaagct cgctcaaaaa atacatcgag
    16981 gacgaggatc tgcttgagga taccctgatt gagacccagc aggctattga gatggctggt
    17041 atttacgaaa atgtcctaaa tgccatgacc gaaacaaccg cctcaatcat caacaacaat
    17101 cagaatacca tcatgaaaac actggctctg atgacgatgg ctctagatat tccaacggtt
    17161 atcttctcag cctatggcat gaactttcag gataattggc tgccgctcaa tggccttagc
    17221 catgcctttt ggtacattgt gctgctggca gctctgctca gcacctttgt tgttatttat
    17281 tttattagaa aaaaatggtt ttaataaccc catttccaac tgaaaaagct actcctgagc
    17341 tctacctgta gacagctcat cagctaaaac aggcactact actgctaaag caaacaatcg
    17401 tcccagcaag taacggtagc tactactgct tgatcgtatg atcaagcgca acagatcagc
    17461 tgccatacta gctggcaaag caagccagca aggcgccctt gaggcattat cccaggctag
    17521 ctctgcttac aatcatcaca tcatatagga gaatcccctg tcatggactt acaacagctt
    17581 accaaaaaaa atcaagaatt tattcatatc gccaccaatc agctcatcaa agatggcaaa
    17641 actgatgacg acatcaaggc acttcttgag gaggtcattc cgaccatttt agaaaaccag
    17701 aaaaaaggca tcactgcaag aagcctatac ggggctccaa ctgcctgggc agcttccttt
    17761 agtaaagaag caaatcaaaa agaagccaca cccaaaaaca ccaatccatg gctgatgtgg
    17821 cttgatacct cgcttctatt tatcggtatt gttggccttt taaacagtat catgaccttc
    17881 tttaacacca acgctaccgt caccgggctt gtgtccttac ttgctcttgg ctttggaggg
    17941 ggagcttcca tgtatgccac ctactatttt gtttatcgcc atatgggcaa ggacaagagc
    18001 cttcgtccaa gctggtttaa ggttattggt gctctgacac ttgcaatgct ggcctggata
    18061 accctctatg ctgctacagc ctttttacca aaggcactca acccacaatt acctcctgta
    18121 gcacttctca ttaccggtgc cttagcgatc ggactgcgtt acctcttgca gcgcaaatac
    18181 aatatccaaa acactatgac accacagcgc tagcagcagc tccacgacgt gaggagacgc
    18241 ttccttgctc ccttaagggc agctagcctt tttataccat attgctgcaa caccagacac
    18301 tgatctacaa tcgacactcc tcaatccgtt agatgaggag tttttcttta gccctatgct
    18361 tcatcaaaca gtgccagtag ctctccaaat caaaccacaa gctaaggact tgattgctag
    18421 cagcatagct cagaccatac aaaaaacagc ccctaaggac tgtttcagat attagtcttc
    18481 gtttacgtaa ggcataagtg ccataacgcg agcacgtttg atagctgttg ttactttacg
    18541 ttggttttta gctgatgttc ctgttacacg acgaggaagg attttcccac gttctgaaac
    18601 gaaacggcta agaagctcag tatctttgta atcaacatat tcaattttgt tagctgcgat
    18661 aaagtcaact tttttacggc gcttaaagcc gccacgacgt tgttgagcca tgtgttatct
    18721 cctttatatt attcaaacga taaatttgcc gcctaataag caaaccgacg ccagaaagag
    18781 gcctcaatct tttgtgcttg aaagcaactc ctctgtctcc caagctacca gcaaatctat
    18841 gcaattcatg tcagtccact ttccattgtt tagaatggaa gatcgtcatc tgaaatatcc
    18901 attggatttg agccgccaaa tggactttca tctctgccaa agttaggtgt ttgctgagca
    18961 ggcgctgaat agctattggt tgccggtgag ctattaaaac caccaccata tgagccagac
    19021 gagttcgcct cacgtgtagc acgactttcc agcatttgga aattatctgc aacaacctcg
    19081 gttacataca cacgctgccc ctgttggttt tcgtagttac gagtctgaat acgtcccgta
    19141 atcccaatca aggcaccctt tttagcccag ttagctaaat tttcagcttg ctgacgccag
    19201 atcacacagt taatgaaatc cgcttcgcgc tcaccatttt ggctcttaaa ggcgcgatta
    19261 acagcaagtg taaacgtagc aactgccacc tgacttggag tgtatcgaag ctctgcgtcc
    19321 ttggtcatac gaccaactag tactacatta ttaatcataa actacctact ttgcaattaa
    19381 gcatcaagct taacgatcat gtgacgaaga atgtcaccgt tgatttttga cagacggtca
    19441 aactcattaa gagccacagc gtcagtcgct tcaaggttta cgatatggta aaggccttcg
    19501 cggaaatcat tgatttcgta tgcaagacga cgtttttccc aatcttttga ttcaacaata
    19561 gttgcaccat tgtcagtcaa gatagagtca aaacgtgcta ccaaagcgtt tttagcttct
    19621 tcttcaatgt ttggacgaat gatataaaga atttcgtatt tagccattga tagtttcctc
    19681 cttttggtct aatgacctag acgatcacat ctaggtaagt gaggtatgct cacagtctaa
    19741 cagtatacaa caaacaaagg taaaaagcaa gcaaaatgtt gacttttata ttgagaaaaa
    19801 atgccttctt agatcccttc gtagctccat aaaaagcaaa gccatctcta tagaaatgac
    19861 ctttagtcac ctgacttgca ggtcttagtg gcaaggtcaa atccagacac cagcaaaaag
    19921 gacacccaac cgggcgtcct tgtcatgtct tgagtgctat tctcccttct atctgccatt
    19981 tcataaggag tcacctgtca attgttcctc taaggaggaa cacatactta tctgtctaat
    20041 cagtcgtctc ctttctgttt aacaaaatga acggttatta aaagaatatg actgttcttg
    20101 agtttcgttt gttagcactg tgctatttca gcttacattg gactcactcc ttcagctatt
    20161 ttttgctgtc gtgctcaatg tctccgtttt tatatcttgc gatgtacata agaccctcct
    20221 attagaaaag ctcactagct atctgatgat agctaccttt caaataagct caatccttta
    20281 ccctgagtgc caataacaat atcaaggacg actagtgaca cagcaactag tctccatttt
    20341 tatagcgtcc tttattgaat cttagcatag catacgtcct ttcaataacg ggaatttcaa
    20401 gcttatactg tttagagcgc tcctttggcc aaagctggta atcttgataa gccttcacat
    20461 gtgatcacat attaaattgt aaaattggtt ttgcctaccg tttgttggag ctcttaatct
    20521 ccatttttgt accgcgcgac atgtcttgtt atcatcagat gtcctcctat aactccagtg
    20581 tcatcggtcg tccttatcta tatctttatt ataatgtaag cggttactga agtcaagctt
    20641 tttgctcctt ttttgataac atatcagcaa ctaaaactcc acgataggac acaagccttc
    20701 ggcaaagact gagaaccttt ttatacttgt catttacgtt caagtgcctt tgtcaatacc
    20761 tcagagtcat taaccttttc gcgatcagct aatctaacca accactctgg aacggcaaca
    20821 tttttacgaa cagctttatt atttttgata aatggtgttg aatcagcttg taggaactgg
    20881 caaatccaga ccataatcaa tataatcagc aagaacattt tctaacatgt catgagcagt
    20941 tgtcacaacc tcttcataag gtataaatca caaagcatgc tttaacaaat cctatcagac
    21001 gtggggttca accaattcag acaatctgtg ttacaatagg attatgatag atttaaatga
    21061 ttatggcatt accatgtggg atcaagatac cattgcctcc tttcgtcgta cgctgctagc
    21121 ttggtacgat caagaaaagc gagacctgcc ttggcgccga acaaaggacc catatcatat
    21181 ctgggtctca gagatcatgc tccagcaaac gcaggtcgtt accgttatcc cctattacga
    21241 gcgattcttg gattggtttc caacggtaga ggctctcgcc tgcgctgatg aagagcgcct
    21301 gctcaaagct tgggaagggc tgggctacta ctctcgtgta cgcaatatgc aaaaggctgc
    21361 gcagcaaatc atgactgact ttggcgggat tttcccaagc tcacacgctg atattactaa
    21421 gctaaagggc attggccctt atacagctgg cgctatctca agcattgcct ttgatctgcc
    21481 tgagcctgcg gttgatggca atgtcatgcg agttatggcc agactgtttg agattgatta
    21541 cgatattgga gacccaaaga accgaaagat ttttcaggct gttatggagg tgcttattga
    21601 tccggatcgg cccggagatt tcaatcaagc cttgatggat ctggggactg atattgaggc
    21661 agctaaaaat cccagacctg acgaatctcc tgttcgtttt ttctgcgcag cctaccgaca
    21721 tggcacctac gacaaatacc ccatcaagga gccaaagaaa aagccccgac ctattcaggt
    21781 gcaggccttt gtgattcgtg acagtcaggg gcggcttttg ctcgaaaaaa atacgcaagg
    21841 acgcttgcta ggtggctttt ggtcctttcc attgatagag actgactttg tcagccaaca
    21901 gctgaccctc tttgaggaca agcctgtcgt gcttgagacc atgtctcaaa cagccctttt
    21961 tgaggagcgt tacggacttg tgcctgactg gtctcaagtg gcctttcctc aggtcaagca
    22021 tacctttagt catcaaaaat ggaccattga gctttgcgag ggcttggtag atcaggcacc
    22081 gctaccctct gatagagagc ttgcttgggt cacgctggag gatatgacgg cctatcccat
    22141 ggcaacacca caaaagaaaa tgctggaggc ctacttaggc aagcgcagct aaatagctca
    22201 taaaagctag acaaagcctt taacagcgat gttagaggct tttttgcatt cctaaacagc
    22261 ggctggggta tactccatct gaccagcata aggcaggcta agcttgtaac aaaatcagac
    22321 gattgtcctg ttcattaaaa aaaaaacgaa actacggaga caaattggga cactgctatg
    22381 tcttgtcgtc agctgtcgtg ctacactggc cttagaaacc agtcacaaca aaaagctgtg
    22441 acaatgataa ctaaataagg agaaaaccaa tgaagctgac aaaaacccta tgtctagtag
    22501 cagctactgt aactctagcc ctagcaccaa tcaatacaag cacaggacaa attaatactg
    22561 tcttggcaat gcaacaaaca aagcaaaata attatccaaa aaattgtaaa aaaattgact
    22621 ctcaatactt tgaatgtcct gacggcaagt tatattacaa tggatacgat ccatactcat
    22681 tctcagcatg ggtcggccga ttcttttatg ccttttactc tgtatggagc actctgaatg
    22741 gaatattcaa atagctatca aagcaggtca agactgtagc gacctgcttt tttatcagcc
    22801 ctgctattgc ctcctggtct gctgagaaat cagacaatta gccttttcat taaaatcaaa
    22861 aaccaaacga atctaggaga gaaagtagcg gacaactgtt tctctatctc gacgactatg
    22921 ttagaatatc ttcagtcaaa attaatatgt ctatcatcaa aggagagaga gatgaacaaa
    22981 aaatcagcaa gacgcaagcg taacgatatc atcgcgaagc ttgcgatgac aagtgcctta
    23041 accctaggtg ttggcgcagc agctaccatg acaggacaaa cagaggcaaa agctgaagtc
    23101 ctatacatgg aaaatttgga tatgagagat aaagcggcag ttgaaaaatt tgccaatgaa
    23161 ctaaaggaat tagtgaaaaa aaaagagagt gatcataacc tagcttggcg taaactttcc
    23221 ctcatactta acggatataa aaattttacg caaaaaattg aaactgaatt acaagcaagt
    23281 cagcaaaaag ttcaagagct taatgagcta attagcaaag aaaaagaaca gttagaagcg
    23341 ttaaaaaaag agctcgaaac tgaaaaggct aaagaagctg aagacatagc taagcttcaa
    23401 aaggaaatta cagaaaaagg tgaaacaatt tccaatctac aagggcagct tgaagctttt
    23461 ggccaaaagg ttaaagagct tgaagctgaa aaagcagcgc tccaagaaaa attagctatg
    23521 caagagcaag ctcatgctga ggaaaaagct aagcttcaaa aagaaattga agacttaaag
    23581 gctcagcttg aaaagcttaa gcactgtcaa gatacaccta agccagagcc taagccagag
    23641 cctaagccag agcctaagcc agagcctaag ccagagccta agccagaagc taagaagcct
    23701 gaacaaccta aaccaatgac taaaccagga gctaagaagc ctgagcaatc acttccatca
    23761 actggtgaca tcagaaatcc attcttcacg cctgcagcta ttgctattat gatcgcagca
    23821 ggtaccattg caattccaaa acgcaaggaa gaagattaaa caaattaaca atccccatat
    23881 ttcaacaatg atacacaagc ccctacttgt gtccacctca aaagcagtag ccagtcgcgc
    23941 ggctactgct tttactatgc tttttttaca ccagctctga tagcagctaa taacaaaaaa
    24001 gattgaagac acagcttatt gggtccccaa tctttttttg gtcatacaac caacagcagc
    24061 tcttgaggct tgctgtcctt ctaagaggct gttggcttgt tgctttagct taattctgct
    24121 acgatagcct tgatttgatc cttggtatgg acgcctgcta cttgcttgac aaccttaccg
    24181 tcctttttga acagcagggt tgggatagac ataatgccaa attgttgagc agtattggga
    24241 ttgtcatcaa catctagctt gacaatctta agctcagctt cgtcaatttc tgctgctaat
    24301 tgatcaagga ttggcgcttg cattaagcaa gggccgcacc aggttgccca aaagtccaca
    24361 aggactaggc cttcattagt ttctgcttca aatgttgcat ctgttacgat atgtgccatt
    24421 gtaatctccg ttcttatagt ttataagcct attttagggg aaaacgactg ataatgcaag
    24481 aatctgatac gaagacctcg gtcttatgat ttaagaaaaa tctggcgtag ccattttaag
    24541 acaaatacgc tggcctttgc tacaatgacc ttatcttaac aactaaaagg aggctactat
    24601 ggaagcatac gagcttattg tgattggatt tggtaaggcc ggaaaaacct tggctgccaa
    24661 aatggcgcag ctaggaaaaa gagttgccct tattgagcag agccccacta tgtatggcgg
    24721 gacttgtatc aatatcggct gtattccaac aaaggcctta atcactgctg ctgagcacaa
    24781 tgctagcttt gcagacgcta tggcgcacaa ggatactgtt gttcatcgtc ttcgccaaaa
    24841 aaatgagcag ctgctagctc agtctggtgt gacactttac aacggtaagg caagctttgt
    24901 ctctaataag acgattcaag tagaagcagg gcaggagcag atcctcttag agggcaagca
    24961 tatcgtgatc aataccggag ctgtttcaaa tcgctttccg atacctggtc tagcagatag
    25021 tcagcatgtg gttgatagca cagggattct ggctctcact gagcagcctc agcgcttggc
    25081 tattatcggt gcgggcaata tcgggctaga gtttgccaat ctttatgcca gcttaggcag
    25141 caaggttact atgtatgagg ctgcccctgc tattttaggg cgctatgagc cggttgtcgc
    25201 tgagctggca caggattatc tggaaaaagc tggggttacc tttaagctct ctgcaactgt
    25261 tgagctgatt gctaatgatg aagcaggtag agttctagtg actgctaatg gcaagacaga
    25321 agcctttgat tgtctcctct atgctatggg acgtaagcct gccactcaag gccttggctt
    25381 ggaaaacact gacattaagc ttgatgatcg ctatgctgtc gtggtagatg attattgtca
    25441 aaccactgtc gaaggggtat atgcggttgg tgatgttaat ggcggacctc aatttaccta
    25501 tacgtcctta gatgatttca ggattgtgtt tgggcagcta acaggcacaa gccagtacaa
    25561 ccacaaagat cggggctatc tgccaacaac agtttttatc gagccgccac tttcacaaat
    25621 tggtctaaca gaaaaagaag caaaagagca gggactaccc tacaaggcta atgagctctt
    25681 ggttgccaat atgccacgcg cccatgtcaa taacgacctc agagggattt ttaaggtcat
    25741 tgtcaacaca gaaaccagtg agattctggg ggcaacctta tttgctaaca attctcacga
    25801 atacattaac ctgattaaga tggctatgga taaccagatt ccatatacct atctcaaaaa
    25861 ccagctcttt acccacccgt caatggctga aaatcttaat gatgtcttta acctttaaaa
    25921 gaacctcaac ctcacctgca tagcaggtac aacagccaaa ctattaaaaa aacaaactcc
    25981 tttttggctg cttatcacat ggataggcgg ctagcaaaag gagcttgttt tttcttgtat
    26041 ccagtaagca agtcagtagc tgctcatggc ctaaggaact agctaggcta ggacgtgttg
    26101 gcagcaaaag tccagcaaga ctcactagct gctgtcatga gctttgaaga gcagcaatta
    26161 gggaacacgc ccagtagctt tcttcgggac gcttgtgtca cctagggctc aatcagcttg
    26221 agtacagaaa agaggctttt gttttgactc aagaggagca attagcctag attagctatg
    26281 gtacagcctg agccgccagc attttgcggg gcatagccaa agcttttgac gtgcttgttg
    26341 cgtcgcaagt acttgccgac cgcctcacgt ataacacctg taccaatacc atgtatgatg
    26401 tcaacctgac tcatgttgtt cagcaaggct tggtcaataa aggcatctag ctcctgcatg
    26461 gcctcctcgt agcgcttgcc tcgaaggtcc aagcgagcgc gcggcccttt tcctgtagct
    26521 gcttttttga cgaccttgac agctctcttc ttaggctgct gcgcttcttc ttttagctta
    26581 accaagctga attcctcttc cttgagggtc agcttaatca ggccaacctg agcctcccac
    26641 ctcttgtcct taagctgagc aagcaagatc cctctttgac cataggcagt aacaatgata
    26701 tcatcaccca cacgaggagc tcgccatttt ttggcttgtt tcagtacctt gttttgtgat
    26761 aggctttgct ctggggcaag ctgctttaag cgatgcttgg cttcgatgat ttcgtgcggc
    26821 tttagctctg ccttttcatg cagctggctt aaaatgctat cactttctgc caaggctata
    26881 tccacaatct cacgcgcttc aagggctgcc ttttccaatt ccttgtcctt ggcgtgggag
    26941 aattcgttat agagcttttt aacagcacga ttgaatttga ggttatcctg ctcgacctcc
    27001 ttgatatgtt caaggcgctt gcggctctcc agcgtttgct gctccagctg ttcaataata
    27061 cgattgacat catgatcagt tgcggtcatc gcctgagctt ccttgacgat gtgctctgct
    27121 aagcccaatc gtctcgcaat gtcaaaagca tttgagcgac caggcactcc ttgcataaag
    27181 cggtaagtag gctttaggct gacattgtca aaggccatgc tggcattttc aacataggct
    27241 gtctcaatcc cataggcctt tagctctggg taatgggtgg tggccatcgt cttaatattg
    27301 gtcagacgca gctgctccaa gatggccata gcaaggctgg ctccttcctg cggatcagtc
    27361 cctgctccca actcgtcaaa gaggatcaag ctgtcactgt ctgcctgttt gagaatctca
    27421 acaatgtgag tcatatgact ggaaaaggta gacaggcttt gctcaataga ctgctcatct
    27481 ccaatatcag cataaatacc attaaaaact gccaccctag agcccttatc agctaaaata
    27541 ggcaggcctg actgggccat cacctgagca agccccaagg ttttgagcat gatggtctta
    27601 ccacctgtat taggaccggt gatcacaatt actgctaagt catttgcaaa atgcagatca
    27661 tttgccacag ggttttgaat caaggggtgg cgcgcattga gcagctgtaa gcttttatcg
    27721 tcagaaatca ctggcacagt tgcctgtttg gcttgcatat aaaggtattt tgctctcaca
    27781 agatctagat gtcctagtag ccaagcgtta ttcctaagag atcgactatg cggacgcagc
    27841 tgctctgaca gctcatgcaa gattcgtccg atctcatggc gttcatctgc ctgtagctga
    27901 gtcagctcct cattgagact tacaagcgct ctaggctcaa tgtagaccgt actgccagat
    27961 gctgacatgt catgcacaac tcctgctact ttatgacgat aggtgttttt gacaggcagg
    28021 acacttcggc cgttacgact agcaatcaag ctctctgaca ggtaagctgc ctgttttttt
    28081 aggatatcct gcaggagctg acgactggca tgctccttgt ttgatatctg acgacgaatg
    28141 ctctccaatt caggactagc aaagccttca acaaagcctg cgtcattaat ggcttggaga
    28201 ctcccctgta agctaggaaa gctctctatt ttttcgaaga gtgcttttag agcgactaaa
    28261 tcaacatttt ccaaatcagc gtaaaaacga cagacctctg ccgacacctg caggagcttt
    28321 ttaactgcta aaagctcttg aatgctcaga tctgcctcta aatccaaacg ctgcatgctt
    28381 tctgagacat ctgatagccc tcccaaggca aaatggtggt gctctacaaa aatagccgcc
    28441 atttcctcaa gctctgtaaa gtaagcctgt attttgtctt tattagcaat aggctccagc
    28501 aaatcaagct cgagctgccc ctgctctgtc tgtaaataag gccaaaattg ctccttaacc
    28561 ttgtcaaatt ctaactgttc taaaatcttt ttttccatag ttcttattat acctaaaaat
    28621 cacttaaaat gtgggacact aaacaaaaag agaccagaga gactctgacc tcaaagaata
    28681 gcagttaccc ataattgcct gagaatgctt gagataaagg gacaatgctc aaccaagagg
    28741 cgagacaaaa gactgccatg taggagccct tgaataaagg gcatgggaat ggtagcaaga
    28801 atggtcaacg ccatgcttaa aaacaaaatc gaaaccagca ccgccagcaa gccactggct
    28861 agcttagcct caaagccatc aaaataatcc accggcgcaa ggtgcactaa gacacccgcc
    28921 aatcgaacca cagcatagcc tacagtagac agtataaaaa atgctatccc tgcataataa
    28981 accttatcca attcaaaaat attaatatcc ttaaaaaata aggtggttgc tccctcagca
    29041 ggattggaat aaggcaccca tagagccagc ttgccagcca gagccttata gccatgatgg
    29101 gcaaacaaga gcgacattaa agctccaaaa caataaaagg tctgaaggat aagccctcta
    29161 ttgtagccaa tgtaaaagct ccaagaaagc agtaacaata taagcactga gagcatcatg
    29221 acacctcatc tgtatctgct tgactagcct tttcctgaat acctgccagt gccttctcac
    29281 gcagctcgac aatctcagct tcgatttttt caatctcaat ctctctactt agctgggctg
    29341 acagggtatt gatggtcatc aaaattgcaa cagtttcgtc gtctgcttct ggcagacgct
    29401 ccttgatggc ctgatatttt tcctttgcca cacgatcaac ctcttccata aagaggttgt
    29461 ctttgtccgt tgtcaatgtt aatgtcttct caccaaatgt taatttgtaa cgattaatat
    29521 tcttcatagg ctcacctctt tagcattata ccctaaaaat gacttttcgt aaaattgtga
    29581 aattaatctg agattgcagg gaatgatttc ccataatagg acattttatg ttaaaataat
    29641 gttcatggac accttagttt tcaaaatcaa ttcccaagtg agcagcagcc tgatcaagca
    29701 gctagcacca taccgcataa gcaatgccag cccctacgtt aggctagctg ccaaaaaaga
    29761 tggtgtcaca ctgatgctgt atagctcagg caagctggtg ctgcagggta gacaagcggc
    29821 aggactggct caggagcttg gattacaaga gactgctgct gatcaaagac ccgcaccctc
    29881 tagcgcacag gatatgcccc taattggcag tgatgaggtg ggaaatggct cttactttgg
    29941 aggcattgct gttgttgcca gctttgtgcg gccagaggat cacgccttgc tcagacagct
    30001 cggtgttgat gattctaaaa acctcagtga tatgagcatc gtccagatag ctcctgtcct
    30061 aaaaaagcat attcaacaca gggcactttt actatcgcct aaaaaataca atgaaatggt
    30121 gggcaagaat aagccctaca acgctgtttc tgtcaaggtt gctcttcata atcaagcgat
    30181 ttttctgctc ttaaacgacg gagcaagacc cgaaaaaatt gtcattgatg ccttcacaag
    30241 tcaggccaat tatgacaaat acctacagca agaaaaaaat cacttttgca atcccttgac
    30301 ctttgaggaa aaggccgaag gcaaatatct ggcagttgct gtcagctcta tcattgctag
    30361 acagctattt ttagacaatc ttgacaagct cagtcaagat ctgggctacc ggttgcctag
    30421 tggtgctggg cgtccatctg atcagattgc cagtcaagtc ttagccgcct atggtatggc
    30481 aggcttagag cattgcgcta agctgcactt tgcaaacacc aaaaaagccc aagcgctact
    30541 aaaaaaacaa taatcttaga aaaataaagg aaaagtcatg aaacaattta ttaaagaatg
    30601 gggagctttt acccttttta tcctactttt tggactctca cgtttgttcc tatggcagcc
    30661 tgtcaaggtt gatggccact caatggaccc aaccctagca catggcgaga ggctcattat
    30721 cttcaacaag gctaagattg atcgctttga tattgttgtt gccagtgagg aggacgagaa
    30781 cggacagaga aaagagattg ttaagcgtgt tgttggcatg ccaggtgata agctgtctta
    30841 tagaaatgac actctttata tcaacaacaa gaaaacaaaa gagccttatc ttgataccta
    30901 cctgacgagt tttaaaaagg acaaattaca atcaacctat gcttacagtg atctcttcca
    30961 agagctggct gaaaatgctg ctgcctttac cgtcaactcc gaaggaaaaa cagaatttga
    31021 catcactgtt ccaaagggcg aatatttcct actgggtgat gaccgcattg tatctcgtga
    31081 cagccgcgag gtcggctcct ttaaaaagca ggacatcgtt ggtgaggtta agttccgctt
    31141 ttggccactc aataaaatca atctcttccc tagatagcag gcaagctaaa gctattttct
    31201 agcagggctg atagaggctc tatgcctaca gcagcaatag cctctatctg tatctgctta
    31261 tctatccata ccaaaaggct tgatgtgcta tccaagcact cagctagctt tagagaagca
    31321 gctattgtta acgttctaga acctgccgct gtgcaggttt tcgactatct tgtacagaaa
    31381 ggtactgtca tggaacattt ttttacgggc actgttgacc ggattatctt tgacaatgcg
    31441 tcaaattttt tcaaaattct attactggct atagaggata ctgatagtga ttttgatgag
    31501 gctgacattg tcattacagg cactatggct gagatcatag agggcgaggc ctataccttt
    31561 tggggtgagc tgacccagca cccaaggtat ggtcagcagc tgcgcctaag ccgctatcaa
    31621 aaggctaagc cctcctcagc aggtcttgtt agttattttt cgagtgagca tttcaagggc
    31681 attggtcaaa aaacagctga aaaaatcatt gccctttacg gtaataaccc tattgatgac
    31741 attttaaaaa atcccagtcg gcttaatgag atctctggcc tttctaaggc taatcgtgaa
    31801 gcctttgtgg caaagctcaa agccaattat ggcactgagc aggtgattgc tgccttagct
    31861 gagctaggac tggccaatcg ctttgccttt cagctatttg acaaatacaa ggaagaggct
    31921 gttcatattg tcaaggacaa tccttatcag ctcattgagg acattcaagg ctttggcttt
    31981 aagatggctg atagcctagc tgagcagctg gggattgaga gtgactctcc caagcgcttt
    32041 cgtgcagccc tgcttcattg cctgttggag caatccatca aacgaggcga cacctatatc
    32101 caagcacgtg agcttttggc gctgaccatt agcctattgg aggatacaag accagtcgaa
    32161 tgcgacccgg ctattgtcgc caatcagcta acccagctca tcgacgaggg caaggttatg
    32221 accattggca cgcgtgtctt tgacagcagc ctttattatg ctgaagaggg cattcaaaag
    32281 cacctgacac gcttattgca gcagcccctg accaaggagc ttagccaaga caccattgac
    32341 caagacattc aagcaataca agaggagctt gctatagcct atgacgagat ccaaaagcag
    32401 accatcagcc aggcactgac cagtaaggtt tttattttaa caggaggccc aggcacagga
    32461 aaaacaaccg ttatcagggg cattttacag gcctatgcca gcctacatca gattgacctg
    32521 aaaaaaaagg atattcccat tatcctagca gctccaactg gtcgagctgc tcgtcgcatg
    32581 aatgaagtga ccggtctagc aagcgcgact atccaccgcc atcttgggtt aaacggagac
    32641 aatgattacc aggcaatgga ggattattta gattgtgatt tgctgattgt tgatgagttt
    32701 tccatggttg atacctggct ggccaatcag ctgctaacag cgatcagctc taacacccag
    32761 ctgatcatcg taggagatag cgaccagctg ccttctgtcg gtcctggaca ggtactagct
    32821 gacttgctaa gggttgatcg gatccctcac attacccttg ataagatttt tcgtcaatca
    32881 gaggagtcaa ccattgttga tttagccaat cacatacgtc aaggcattct tgcccctgac
    32941 ttttgtcaga aaaaggctga tcgctcctac tttgaagcgc aagcgccatt cattcccggc
    33001 atgatgacaa agatcgtaca ggctgcccta aaaagtggca ttccagccga ggaaattcaa
    33061 atcctagccc ctatgtataa agggctagca ggcatcaaca gcctcaatca gctcatgcaa
    33121 aatctcctga atcctctagc tgatcagaca gaatttctct ttaacgagac ggcctttcgt
    33181 aagggagaca aggtgcttca ccttgtcaat gacgcacagc ttaatgtctt caatggtgat
    33241 attggctata tcacagacct cattccagcc aaatataccg aatccaagca ggacgaaatc
    33301 gtcatagact ttgatggcac agagattgtc tacccaagaa atgaatggtt aaaaatcacc
    33361 cttgcctatg ccatgagcat tcacaaatct caaggcagtg aatttcaggt ggtaatcctg
    33421 cctgtcaccc gtcagagtgg tcgacttctg caaagaaacc tcatctacac tgccatcacc
    33481 agatcaaaaa gcaagctcat catgctcgga gaaatagccg cctttgaaga ggcaatcaaa
    33541 aaagaaggtg acaagcgaca cacctatctc gtacaaaggc ttcaagtggc tgaagctgat
    33601 gaccatacag cagctgcttc agtaaaggaa tcaaatcagt ctagcctatc tgtaatgcca
    33661 gctaccagcc cacaaaagga acaagagcag cctccttatc tgctcacccc ttataatttc
    33721 ctaactatag accccatgat tggtctaacc gaagatgata tgttaacctt ttttaagaaa
    33781 aaaaacataa tatattaaaa aagtaaggca caatccttat tcctgtgcta taatatccat
    33841 gtatcatctt aaaagtacaa taacataaca ttcaaggaga cttatatgat ttcatacgaa
    33901 caagtacgac aagcactcag aacatcaact attacgatca ttatcatcaa tgctatcagc
    33961 atggttatca ccttgtttgg acttgctggc attttctttt tgaagtctca attggataaa
    34021 cctgaatttc gtgcacaatt ttcagctgag cagctaaggc tatttgaggt tggcatatca
    34081 ccctttacta tttttatgtc agtgattagc cttggattgg ttgttttgac cactgtgctt
    34141 tgtggcttta acctctcaaa aatcaaacaa ggttccactg tcagctatgt tccttacatt
    34201 atagggattg tgctctatct tattagtatc gtaagccaac tatttagcca aattgagcct
    34261 gtctcaatga tcattgtcct agctgagctt gcgctttacg gctttgcctt ttacaaggct
    34321 aaaaccctta atgaaaaaga caaggacaag ccccaaagca ttgaagaata agcaggccat
    34381 aaaggtatga taacaagact tcctgtctac cttcaaatat ggctctttgt cagcccatta
    34441 cggttgacaa agagcctttt ttaaccacta aaaaagcaag aggaaaattg ataatgtcct
    34501 cttgcttttt ttgttagttg aatgacaggt ccaacaaaat atctgtcact ttatccttta
    34561 gtccggtcat tgtgactccc aataagcgga ttcctgcctg atgctcctcc aggctatcaa
    34621 aaagctctct agccacctga tcaatgatcc tagcatctct tgttaactca ggtaggctga
    34681 cccgcttggt caaggtcgta aagtcagcat accgaacctt caaaacaatg atccttccta
    34741 gttttttatt cgcctcaagc aaatcagcga cccggctggc atttttggaa agctccgcct
    34801 taatatcagc ctcttgatag aggagcttgg cataggttcg ctcactgctg atggatttgc
    34861 gaatacgatt aggcttgact ggcgaatggc taatgcctct ggcctttcga taaagctcat
    34921 agccaaagcg cccaaactga tcaatcaggg tcatctcagg aacacgcaag aggtcctgcc
    34981 cagtgtaaat ccccatctca tgcagccttt caactgttcg cttaccaacg ccatgaaact
    35041 tttcaatcgg aagcttttct aagaatggca gagcatcatc aggaagcact agagtcagac
    35101 cctgtggctt ttcaaaatca ctagctagct tggctaaaaa tttgttataa gaaacaccgg
    35161 cagagcaggt caactgtagg ctattccaaa tatcatgctg aatcagtctt gcaatcttta
    35221 aggcagactt gatgcccagc ttattgcttg tcacatctaa ataagcctca tcaatagaca
    35281 caggctccac ctgatccgta taacgtttga aaatctctct gatatcataa ccaatcctac
    35341 ggtacttagc atgatctcca gagataaaaa tagcctgagg acaacgctcg taggcctcct
    35401 ttgagctcat tgcagagtga atgccatact ttcttgcctc gtagttacag gttgatacaa
    35461 caccccgtcc accactttct ctagggtcct taccgatcac caccggcttg ccctttagct
    35521 caggattatc tctttcttcc accgcagcaa aaaaagcatc catgtcaatg tgtataatct
    35581 tgcgtgaggt gtcattaatc agcggaaaaa taagcattag ttcctccctc ctacattata
    35641 ctcctttagg ctcttaaagc caagacagag cattatatga cagttttcaa ctgtttcagc
    35701 aaactgtaat ataaaagaat cttgtatttg tcaagatttt tgcttgggaa aacgtttccc
    35761 ctatggtaaa cttagattgt aaatgtaaca gattggactt gttactagat tttaaggaga
    35821 aacttatggc aactgttaaa actaacgcag atgtttttga aaaagcttgg gaaggcttta
    35881 agggaactga ctggaaagaa aaagcgagta tatctcgttt tgtacaggct aactatacac
    35941 cttatgacgg tgatgagtca ttcctagcag gtgttactga gcgttcattg cacatcaaaa
    36001 agatcattga ggagactaaa gctcactatg aagcaacacg cttcccatac gatactcgtc
    36061 caacctcaat tgctgacatt cctgccggat ttattgacaa ggataaggaa ttaatctttg
    36121 gtatccaaaa tgatgagctg ttcaaattga actttatgcc aaagggtggt atccgtatgg
    36181 cggaaacaac gcttaaggaa aatggctatg agccagaccc agcagtgcat gaaatcttca
    36241 ctaagcatgt gacaacggtt aatgacggta ttttccgcgc ttacacttca aatattcgtc
    36301 gtgcacgtca tgcccacact gtaactggtc tgccagatgc ttactcacgc ggtcgtatca
    36361 tcggtgttta tgcacgtctt gccctttacg gagcagacta cttgatgcaa gagaaggtca
    36421 acgactggaa tgccatcact gagatcgacg aagaatcaat ccgtcttcgc gaagagatca
    36481 accttcaata ccaagcactt ggcgaagtgg ttaagctagg tgatctttac ggtgttgacg
    36541 ttcgtcgtcc tgctgaaaac gttaaagaag ctattcaatg ggttaatatc gcctttatgg
    36601 ctgtttgccg cgtgatcaat ggtgctgcta cttctcttgg acgtgtacca atcgttcttg
    36661 atatctttgc tgagcgtgac cttgcgcgtg gtaccttcac cgaatcagaa atccaagaat
    36721 tcgttgacga ttttgtcctt aagcttcgta ctgttaagtt tgctcgtaca aaagcctacg
    36781 acgctcttta ctcaggtgac ccaaccttta tcacaacctc tatggctggt atgggtaatg
    36841 acggtcgtca ccgcgttaca aagatggact atcgcttctt aaacacactt gacaatattg
    36901 gtaactctcc agagccaaac ctaactgttc tttggactga taaattacca tatgctttcc
    36961 gtcgctactg tatgcacatg agccacaagc actcttcaat ccaatacgag ggtgtcacaa
    37021 caatggctaa ggacggctac ggtgaaatgt catgtatctc atgctgtgtg tcaccacttg
    37081 acccagaaaa tgaagagcaa cgtcataaca ttcagtactt tggtgctcgt gtaaacgtgc
    37141 ttaaggctct tcttactgga cttaacggtg gttacgatga tgtgcacaag gactacaagg
    37201 tatttgacat cgaccctgtt actgatgatg tccttgattt tgatactgtt aaggctaact
    37261 ttgaaaaatc acttgattgg ttgactgata cttacgtaga tgcgcttaac atcattcact
    37321 acatgactga caagtacaac tacgaagctg ttcaaatggc attcttacca tcacatcaac
    37381 gtgctaacat gggatttggt atctgtggct tcgcaaatac tgttgatacc ctatcagcta
    37441 ttaagtatgc gactgttaag ccaattcgtg acgaagatgg ttacatctat gactacgaaa
    37501 caatcggcga ctacccacgt tggggtgaag acgaccctcg ctcaaacgag ctagctgagt
    37561 ggttgattga ggcttacact acacgcctac gtagccacaa gctttacaaa aacgctgaag
    37621 caactgtgtc actgcttacc attacttcaa acgttgctta ctctaagcaa actggtaact
    37681 ctccggttca ccgcggtgtt tacctcaacg aagatggtac aactaaccta tcacagcttg
    37741 aattcttctc accaggtgct aacccatcta acaaggctaa gggtggctgg ctgcaaaact
    37801 tgaactcact tgcaagcctt gacttctcat atgctgcaga tggtatctca ctaacaactc
    37861 aggtatcacc tcgcgcgctt ggtaagacac atgacgaaca ggttgaaaac cttgttacta
    37921 tccttgatgg ttactttgaa aatggtggtc aacacgttaa cctaaacgtt atggacctaa
    37981 atgacgttta cgataaaatt atggctggtg aagacgttat cgtccgtatc tctggatact
    38041 gtgtcaatac caaatacctt acaccagaac aaaaaactga attaactcaa cgtgtcttcc
    38101 acgaagtgct ttcaatggac gatgccgctg aagctatttc aggaaaataa gctaatctta
    38161 gctagctaag agcctgtccg ttgacaggtt ctttttttat ggctccatgt caactgtagt
    38221 gggtgactga taactaagca cgagaggaga cgaaggttgt cttctctttt gtgatgttca
    38281 aagcgaggaa gatgcgtttt ttaaagttgt caaagttccg aaatccgaac gcattgcgct
    38341 tgatatcttt gataagtttg ttagtggctt ctaacttagc gttagaataa ggcagttcaa
    38401 tggcattggt gatgtaatct tggtagcgac taaaggtatt tagagctgtt ttaaaagtct
    38461 gattaagatg tggtagtgtg tcatgaatta aaccaaagaa atgcttggca ttcttttctt
    38521 gcaggtgaaa aaggagcagc tggtacaggt cataataaga ttttaactca ggcactagtg
    38581 agaagatctt attgagacat tctctaggag ttaaggtttg tctgaaggtg cgagaataga
    38641 aaggcttaag agaccgtttt ctgctatcct tttgaataag cttccagtag tacttaagag
    38701 ctctatattt aagagacttc ttgtcaaatg gtttcatgat gtcactacgt gtttgcttga
    38761 gagctctact catgtgctga acaatgtgaa aacgatcgag aacaatttta gccttaggaa
    38821 atagaatttt aatgagagga atataacttc cagacatatc gacagtgacg actttcacct
    38881 tgtttctagc ctctttagag tacttaaaga aatgatttcg gatggttgtt tgacgtctat
    38941 tatcaagaat ggtaatgatt ttcttagtgt taaaatcctg agcaatgaag gctaatttgc
    39001 ctttctgata agagaactca tcctaagaga gaacttctgg taaattggcg taatcctctc
    39061 ggaaatgata ctgcttaagc ttgcgataga cggtagaagt ggagatagcg agcttagaag
    39121 cgatatgggt gagagcctct ctgttgagta aaagctgagc gattttctgt ctcaccatct
    39181 cagaaatttg gcaatttttc ttaaccaggg tagtttcaga tacagtgact tttcgacagg
    39241 atttgcattg aaaccttctt ttttcaaacg aatgaggcta ggaaagcctc caatttcgat
    39301 aaagggaatt ttagagagct tctggaagtc atacttaatt tgtttacccc tacagtgctt
    39361 acatttagga gggttatagt ctagtgtagc gatgacttcg atatgtgtat catgttggat
    39421 agctttagtc aaggtgatat gtttgtcttt gattccaatg agttgtgtgg tattattgag
    39481 gtgttccata agatactttc taatgagttg tttagtcgct tttcattata agtcttatgg
    39541 gactttttgg tactcaaaaa gccctataat ctccacagtg gagttaccca ctacagaaat
    39601 tatagagcct tttttatcac acatgcaata ggtacagctg tcctcagcag ctgaataacc
    39661 agcagagctg gttgaaacta ctagcaagcc tatcattatc attgtgaaaa tcagacgatt
    39721 aaccttttca ttaaaaaaaa aaaaaaacga aactacggag aaaagctgat gaggagctct
    39781 ttaaggctat cagtcaacat gttaaactct tcttaggaag cgttaacaat aactaactgc
    39841 taagctaaac aattatctat taaggagaat aacaatgaaa cgactaaaaa ccctatgctt
    39901 gttagctact gctataaccc taaccctagc tcctatcagc acaagccaga caacaacaca
    39961 gaccgtatat gctagtgaaa accatcaaaa tctttgtacg aacactggta acggatggtt
    40021 taaatgtccc gatggacatg gagggtggac ttggcatttt gacgaaaatt ataagtcaaa
    40081 tcagcagtcc tttttgggag gattgttggg ctttgctttg tctctatggg gagctattat
    40141 tagactcttt taagctctag cttaactaat cctcaaacaa caaaaataag ctcttagaga
    40201 actaagctct aagggctttt tgctgttctg ataagtaaaa accaagagac aaggacatca
    40261 aaaacaagca ggcctatcag atataccacc tgataggccc acttgtgctc tcattcttat
    40321 ctaggactat ttctgtcaaa ggccctataa atagcatccc gaagctgtcg tctctctttg
    40381 atccacaagg ccctatcatc cttgtcatag gttctattgg tgagaaaaat cgctgcctgc
    40441 tgctcttttt tgttgagcat gataaaaggc cctgtatagc ctgtatgact aatccaatca
    40501 ccctctaggc tccaacccaa agacctgggc ttttcctgtc tgctatagct ttgaaaaagt
    40561 ctatccgaaa agctttcctt caggtaatgc tcaataaata gctccaaatc tctcagcgtt
    40621 gaaaataggc ctgctgatcc tgcggctttc cctaaaacct tagccttggg atcatgtacc
    40681 tctccatcaa gcaccccctt gaccgttgga actgcttctg gccttgggcc aaaggaggtc
    40741 tcagtcattc caaagggagt aaaaaccatc tcctgaaaaa gctcatcaag agactttcca
    40801 tgaaggtgct ctagcatgaa gccaagcaat aaaaaattca catctgtgta atgaaaggtc
    40861 ttatcgtcct tgacctgaag ctggtgcatc gctgctctta attgctgggc attgagctga
    40921 tctcgattgg gaatataagg gtcaagtcca ctagtatggg tgagtagctg tcgcagtgta
    40981 acctccagct tttgagcgtc aggataataa tgccttaaag gagtatcaag agccaaggca
    41041 tcactattga tcatggctat acagacagtc gctactccga caaccttaga gacactggct
    41101 aaatcataaa ccaagccttt ggtaacaggt ctttgaccat caagggtacc gatataatgc
    41161 tcctgccaac cgccacagcg aaaaagggct aagctagccc catgatataa gccttcctga
    41221 atctgctggc ttaccttttc tatgacttct aatgtcattt gacaaaccaa atttcgatct
    41281 gacttgggtc tgaaagaaca agcacccttg cctttttatc taaataaacc tgacaccctt
    41341 tgtcctcaag gtaggtcttt agagcaagca agtcatagct atctgacacc tgaaattcta
    41401 aaatctccaa atcccatgtg acatgcgggg caatcgtcaa atcttgacca gcctccctat
    41461 taaactcaag cgtgaccggc aggcaatcac caaaaataga ctgataaaaa gctctggatt
    41521 gctcgtcatc taaaacattt aagacaatca gatcaaagct aaactgactc agccctctaa
    41581 agtcagcttc cttgtcaatt gcaggaacat catcaacaat gtcaagctcc ttgatatcgt
    41641 cctctgcatg gagtaagaag cgatctccct ctggtgaggt gacttcaaag gcatagcctt
    41701 ttttcccctt gaaaatcaga tcatagtcaa cgccatgagc taggagctgc tcaatgtcct
    41761 taggagcagt tgttttgata acaatcgtgt ttactttctt agggccatct acagcgcgtg
    41821 ttcttgctgc tggagattct tcaattacaa agcgttcttg tccttggccc caagatgaaa
    41881 aaattgatat cgcgttttcc tctgacacta gccttaagcc tagatttttt tggtaaaagg
    41941 caatattaag gtcgcgattg ttaacacgta atactggggt tttaaagaca atattgtcaa
    42001 ataaagtcat atattcctcc taatcctctg ctattataga caaaattcca atttttgaca
    42061 agaaattata tgctttttaa ccgcctgtca cgcgctacca aggcaatata gcactcacag
    42121 ccatcaccag acttactagg tccaatcttc cttcgtgcgc tctatcacaa gcacctttcc
    42181 ttagcgtaac tcatgcacat attggtaaat gcgacttttt caaaatagca catgaagtac
    42241 ctctttaatc tgacttttcc tgaaccaaaa gcgagaactt ttttagttct cacagcagca
    42301 atcacactct tgacaaatga tttcgctctc ctcaataaca gatgatagct ggaattgccc
    42361 ggtttttctt atccacgcgc aacttcacaa gcaccttatc ttcaatactg ataaggaggc
    42421 caccagctta gctcagttca gactcagctg gctcttgctg acaagcattt gtcacaaaaa
    42481 agaaggccta agccttctct tttacttgat ataaaggaat ttgaatgctg ctactgctac
    42541 tactgctgcc agtactggag cggcaactgg tacccatgag taccaccatt ttgaatcccc
    42601 cttggcttgt ccaaggactg attttggtaa gaaatggtga accaaacgag ggcctaagtc
    42661 acgcgctggg ttgagcgctg gaccagtagg accaccaaga gaggtcacaa gagtcatcac
    42721 caagaaacca atccccaagt gagctactgc aagtgagcct gtcacgtaag gagagatttg
    42781 cgttgcagct gttgtttggt catagccagc ctctaccagc ttaccaacaa gctccacacc
    42841 aaagtaattc ttggttaagg ccattgcgcc aaaaaaaagg acaaaggaac caacaaactc
    42901 gttcaaaaag ccattaatgt aggctgcctt acggctgctc ttggcaccat catcaactgc
    42961 tgaaatcgtt gagaaggagc ccaaaatatt attagggtta tctgtctgca caaaataagg
    43021 cttgtacact gcaacaacca ctaattgacc aaacatagcc cctagcaatt gagcaagaac
    43081 atattgtaaa acgtgtgccc aagggaacaa gcctgaaact gccaagccaa aggtaaaggc
    43141 tgggttaatg tgatttccag aaacgttacc aaacataagt gccggcatca tcacaccaag
    43201 gccatagcca aaggcaatca caagccagcc tgagcggtta ccctttgttc cctttaagtc
    43261 aacattggca actgctccat ttcccaaaat aatcaaaaat gcagtggcaa taaactctgt
    43321 gatgtatttc acagtccatg ttatttccat attctctagt ttcctccaaa tgataagtat
    43381 aacagatacc attttatcag ggatactagt tcttgtaaag cctattgtaa gatattgcct
    43441 gcttaatatg tttacagtgt tttttcacaa ttacggacaa ctaataagtc ttttttagca
    43501 tgtcgcagga tatactctga ggtcgatcca atcagcagac gctcaaaggt atttaagcca
    43561 gttgctccta ccatgatcaa atcagcctgc tccttttcag gtatgtcact agctaagagc
    43621 tttttagggt tacctctttc gatgattttt tttatgctgc taacgcctct gcctctagcc
    43681 attttctcgt aatagctcag cacctcctta gcatgctcct cttgtgtgtc aaagacataa
    43741 tcactaacca ttgcatcacc ctgataggcc ttaacatcaa taacatgagc cagcagtaag
    43801 accgcatcat tgcgaagggc aacattaatg gccttctcaa cagctaattc tgattcgtaa
    43861 gagccgtcca ccgcagccag aatccgttta tatttgctta tcatctttgt ctcctttcgt
    43921 tgattagcct ttatcaatag cctttgcttg tgtctttagg aaatacatga ctgcgcaggc
    43981 agctggaatg agccctgcca gccagaacaa ttggcgaaag gactgcacac cagacccaag
    44041 aagcatatcc ttgatgagtc ccaacagata aggtcccgca cccaagccca aatctagccc
    44101 aatcatataa gtagacatag ctgtattaaa gcgatgctct tcaaccccct taatggacgc
    44161 agcctgccca caggacataa aggtcccata gccaaagcct atcaaagcac ctgaaagcaa
    44221 ataagggaca ctgcttgtca cactaccaag caagaaaagc cccagcgcca aaaagagata
    44281 gctagggtat agcacccatt tgtttccctt taggtccatc aagcgtccca tagcaggacg
    44341 ggttatcgtg atgatcaagg cataaaccac aaagaaataa gcccctaccg tcgttaaatg
    44401 aatctctgtt gtgtataatt tttgaaagcc taggacagac gcataggcaa tccccatcaa
    44461 aaaggcaatg agggtaataa acagagcctt ctgttcaata aagctatcaa ccgtccagga
    44521 ttttgtttta gctagctgct ctgagttaag gctaatattt gtcacaggaa aggcaaaagc
    44581 ccccgccaca accactgcaa tcaagacact acacaagaca ataatcaatc gaaaatctat
    44641 gtgcagatta tccagcataa aggtacccac aaaaggacca atagctgctg ctagactagt
    44701 tgataagcca taaaaattaa tcccctctcc gcgcttgcta gctggaatat aggcagtcac
    44761 aatggtattg gttgctgttg agacaacacc gtagccaaag ccgtttagca gcctgacaag
    44821 atacatcatg ccaatcgttg gcatgaaaaa gtaggctagc gttgttagga gataaaaaat
    44881 ggcgcctcct cttagcacta atcgtcgccc caaaacctcc aattgcttgc caaagatcag
    44941 tcgcgcaagc agggttccta ggatataaat ccccgtcgcc agacctgcct cactggtctt
    45001 agctcctaat tccttagtcg caacaaaggc aatgatcacc gtaaacaagt aatagaccat
    45061 atacacaata aaatttaata ctgtgatccc tataaaatgc ttgttaaata atttgtcttc
    45121 cactgaaaat gagctcctct ctatttcatt aacattttac aaaaaaatca gataatgccc
    45181 catttcaatg gtataatata ggtgatacta ttaaacgaca ttagcaaatg ctaagcattg
    45241 ctgcagcaac aaattatata atgataccag aaacacctct aggagaaaag cgtgaaccat
    45301 caaatcttac agcgttatat tgacagtcat aactttccta ttatcgaaaa gggctaccac
    45361 aaatacctga cctttgaaag cttagaggag gattttacgt atatcctaaa ggagggcatt
    45421 gtcaagcaaa gcgttctgtc aaaatatggc atggaattta acctcaggta cgtcacaggc
    45481 cttgagatca cctctgtgct taatactggc tattccaagg acatgagaga gccctacaat
    45541 gttcgcatcg aatctgagac tgccagcttt tataaggttc gtcattccac ctttttaagg
    45601 gatattagcg aggatatcga gctgcagggc tatgtcaagg acttttatca ctaccgcctc
    45661 caaaaatcaa tgaaaaaaat gcagtgtatg ctgacaaatg gtcgtatcgg cgctatctct
    45721 acccagattt acgatttaat gacccttttt gggcgcccct tggctaacgg tcatatcctt
    45781 atcgatttta tcatcacaaa tgaggagctg ggcaaattct gcggcatttc gactgccagc
    45841 agtgtcagtc gtctcctaaa gcagctcaaa aaggagggca ttatccagat ccaggaccag
    45901 catattatca ttaccaattt agaaaagcta aaggataaca ttgtttttta aacattagaa
    45961 aggacatctt atgcgctaca accaattgtc ttacattccc accagtctag aaacagccgt
    46021 agctgagctt caggccttgg gctttgctgt ccagcaagaa caagcaccca aggagagctt
    46081 cgctatcttc cttagaaagc tattttttca ctttcaggat accgattatc ccttgagcca
    46141 tatgattgct actaaggagc tagatcttct atcctttcta gcatctgatg aagcgctgac
    46201 aaaagaggtt tttgatttag tggccttaca ggtccttggc tttattcctg ctgttgactt
    46261 tactgataca caggacttta tacaaaagat tggctttcca attgtttttg acagccagca
    46321 attactactc aatttacatc agctgcttgc gacccggcag aagtccggtg tgaccttgat
    46381 tgatagcctt gttagtcagg gcttgcttcc tatggataat tgctaccact acttcaacgg
    46441 aaaagcccta gcaacctttg ataccaccag cctcattcgc gaggtggttt atgtcgaggc
    46501 tccccttgat accgatcaag acggacagct tgacctcatc aaggtcaaca ttatccgccc
    46561 caaggccagc actgctatcc caagcatgat gacagccagc ccttatcacc aagggattaa
    46621 cgagaccgcc aacgataaaa agctccatcg catggaaggt gagcttagcc ctaaggctcc
    46681 tcgtaggatt accgttgagc caactgattt tcagccgctt gccaccaagc cctcaaggct
    46741 tcctgtcaat gagtgccaag agaccttcag ccatatcagc tcctacacac taaatgatta
    46801 tttcctagcg cgtggctttg ccaatctcta tgtctcagga gtgggaacag caggctcaac
    46861 tggctttatg acaagtggtg actacgccca gatcgaaagc tttaaggctg ttatcgattg
    46921 gctaaatggc agagctactg cttacacgag ccacaagcgt gactatcaaa tcaaggctga
    46981 ttggtcaaat ggcttagtcg caacaactgg aaaatcctat cttggtacca tgtcaacagg
    47041 actggccaca acaggtgttg atggcttagc agtcatcatt gctgaagctg ccatttcttc
    47101 ttggtacgat tattatcgtg aaaatgggct ggtatgcagt cctggtggct acccaggaga
    47161 ggatctcgat gtgctgacag agctcaccta ctcgcgtaac ctgctgccag gtgattactt
    47221 acgtcacaac gaccattatc agcagctgct gagccaacaa tctcaagctc tcgagcgcca
    47281 atcaggcaac tacaatcaat tttggcatga ccgcaactat ctgccacagg ctgatcacat
    47341 caagtgtgag gtcgtctaca cgcatggcct acaggactgg aatgtgaagc ctagacaggt
    47401 ctacaatatc ttcaatgccc tgcctgatgg ccttggaaag caccttttcc tacatcatgg
    47461 tgagcatgtc tatatgcaca actggcagtc catcgacttt cgtgaggcca tgaatgccct
    47521 gctctgtcaa aaaatgctag gacaaaataa tggctttacc ctaccaacaa tcatctggca
    47581 ggataaccaa aaagaacaaa cctggaaaga gctaacagcc tttggcggtc acagcaagcg
    47641 tcagattgcc ctaggcgagg atcatgtctt gattgacaat cactatggcg aagaggactt
    47701 taagcgctat agcaaggatt ttcgtgcctt taaagctgag ctttttgaag gcaaggcaaa
    47761 tcaagcagtc attgatattc tgttagaaga ggatctacca atcaacgggc aagcctgcct
    47821 taagcttaag ctaaaatcaa gtgaaaacaa ggggatttta tctgcacagc tcctagatta
    47881 tggcaagaaa aagcgctttg gtgatttacc tgccattctt gagctagaca gtattgacaa
    47941 cgggcaacaa tttgcgcgtg aagccctcaa ggagcttccc ttcaaggaca gtccctatcg
    48001 tgtggttacc aagggtgtcc taaacctaca gcatcgcagc aacctattga ccatcgagga
    48061 tattccaaat gaccaatgga taagcataac cttccacttg cagccaacca tctatcatat
    48121 ggccaaggga gacaccctaa gagtcgttct ttacacgact gattttgagc atacaatccg
    48181 cgacaatagc aactatgccc taaccctaga tttggagcaa tcctatctcc taatccctac
    48241 tgatgaggag gaataaatca aagcgcatca aaaaagcctg agatcacaat gagctgcacc
    48301 ccaatcgtta gatcctttgt ctaactgttg gagtacagct caaagctcta ggctttttta
    48361 actattttga aaccttttta ccagcctcag caccagaatg caggctgtaa actgattcga
    48421 tatgaatcag acctgctgcc tttggtgctc ccatcttacc ctctgcccat tccttggcag
    48481 cctcaaagac agggccttct gtaatgattt cagcatggcc tacaaagcgg taaccacgca
    48541 gctgctcacg attaacataa gcaacctcaa ttttaccatt ggcttggata tttgaatagg
    48601 tctggccacc agtgttttca ttgtaaacca aggtttcatc gtctaacagt ctcatcgaac
    48661 gcttagggcc aatattagga ttaccctcat tatctacagt tactaccatt gctaattgct
    48721 cagcaatcat ttctttcatt tcttctgtta acatataatc tcctcttaat tgtttctata
    48781 gtcagctgac tacgctttga ttatagcaca gttaagcaga aaagccgaca aaaataggtt
    48841 ggcttaaaaa agttttacag tttacttaat attagaatca ttctcgctat ctggcaagca
    48901 tcctcgaaca cagctacaag gtgattagtg agcaagtact tgttatttca taaaatccga
    48961 atcatcaccc aaaaaaatat catcgactga tatggtcaat gcctctgcaa tacctcttaa
    49021 tttctcatat ttagctcgcc taagcttttg cacatccttt tcatatctgg ctagtgtcct
    49081 aacagaaatc ccagttaacg ctgacaattc cttttgagtc tttttttgag caatcctcaa
    49141 ttcctttaac gttgcttttg acaatatttt ccctccgcct ctcatctcag gtaatattaa
    49201 tgacagatga taagtttatt atagacttcg gtttttatga agtcaagtct tttatcacac
    49261 tttccccact tctttttcta aatcttttga tttagcttga tttgtggtat catatcctat
    49321 atagaaataa aggagaatgg caatgtccga aaagaaaaca ttttttgcaa ctaatttaaa
    49381 atatcttcgg ttaaaaagga atatggaaca attagaactt gctaaccttt tgggacgaaa
    49441 aagctcttcc tcaatcagtg agtgggaaag aggaaagtac actccaaaat ctggtcttct
    49501 gagtgacatt gctgccatat ttaatgtcag cctgacagac ctcatggaaa aggatttaac
    49561 attagagaac aagggagtga cttatcagct tccacaaaga gacttagtga tgatttcaga
    49621 gcaattgtct gaaaataatt acaataaatg gctggatttt ggacaggatc tcttatctca
    49681 tcaggataaa gaagaaaatc ataagccaag caaataaaga gcctcacatg tcttgtttcc
    49741 accaggtctc gaaaaatcac ctaccactca agcacacaaa aagccttggc agggcttcta
    49801 agcataagaa agctgtatca tatcaatgcc tcagggacca tgatatgata cagctttttg
    49861 tatctcactt ttagacaagg tagccacata aggcttgcag atgacctacc tctgtattag
    49921 ctaccacaac caacagctag ctagactggc aggccctcta taagcctcag cggattatct
    49981 aagcactccc aacagctcca acaaaataaa gacataacca ataccattat ttaagatatg
    50041 ggctgctgtt gaaaaataga tattcttctt ccaaacataa actaagccga gcaaaagtcc
    50101 cagtccacca tacacaacga tggaagatag cttgctgaag gaatagatat gaaccaagcc
    50161 aaatagcaat gatgatccca acaatcgagc cagcagcata cctgtgcctg attggccctc
    50221 accgattaaa atcttgcgga aaataagctc ctcattgaag ggaccaataa tactcaccac
    50281 cagaataaag atcactgtct caaagccctc actagcatta tagcgattag ctaaaacagc
    50341 tgcgttgcta ccttctggta aaggaaggct actgagcaaa atatttgcag cataaagcac
    50401 tgcaaaaatg accaagaccc acaaggtatt tttgacccat tttgttgaaa actgctgcca
    50461 gtccctctga taatctgctc gataaagcca acagatccca agtgcaaaaa tcagcaggtg
    50521 tctcccgtaa aataaaaagg tattcaataa aggcggaagc tcaatcacat tgctaacttg
    50581 tctataaaga tacacagcaa tgatatatag catgactagt acagctgcac gatgacgttt
    50641 tatgatatcc aatgattctt cctcaattct aacagtcctc tgattagcta ggctgtattg
    50701 ccattggcta atcttgatct taagcgtgac taacaataag gctttataag cactcaactt
    50761 tttgaattgg tgaggctgac aaacagcgac accccactct caatgatgtt gccccctaat
    50821 ggcgcttgta ctcatcaaga ctagcaaact gaatcccaaa agccctaaca gcaaaatcac
    50881 acagaacaag ataatcttac catatcccta ctaactataa aagcccttaa cctgacctat
    50941 ttgagtgcta atagccaaaa aagcagcgaa aaaacaccaa tcagacacca ccaaggcagc
    51001 tttgatgagt gtagctacaa ctatgcctga gaaaaccctt aaaagcacct cagcagctga
    51061 gctagcccaa acaaggcacc gctcaccaaa tcctactatg ctttctggta gcccttatcg
    51121 actcaaaatt gtatccaacg cctcttgata ttgcttgtct cgcaattctc tgatcacctg
    51181 tgataaatac tctgcctgat acatcacaaa gtcaaaattg aaatccagaa ttttggtgtt
    51241 ctcattcaat gacaacctct ccttgataaa agcagtcatc tcagctgttg tcacaatcaa
    51301 atcaaaatcc gttttacaag gcaattcagc ctctgacaaa atattaaagc gatagacctt
    51361 tgcaacacaa ggactcacct gttgcacgac caagctatat aaaatatcaa tgtttttctt
    51421 attgatttcg attactgcta tggctaaagg tggcaggcct tctctaacaa gctgttccag
    51481 tcgcgtgcaa agcaaatgta aattagagcc tgtcagccga ccaacaccag gaacccgctc
    51541 tgcccagcta ttaatcatca gctcgatacg attggccaag ggcttactgc cttgatattc
    51601 ctccgcataa taatattttt gcgggataaa aagcgacaaa tcaaacaagg tcttacgaaa
    51661 ataaggaatc aaggtctgaa tacaagcctt gtcaaaggcg atatagtggc caaacaattg
    51721 acgcagctca cccagcagct cttggtaagc aggatcctcc tgaatgatcg tcaataaggt
    51781 cgaagaatcc tcctcagacc attgtgtgat cgaaaaagag ttgttaaccg tcaaataaac
    51841 aagaaaaata taatcaatct cgctactggg aaagtccata tcaagcaaca atttcccctc
    51901 acgcttgaaa aagtcctcca aatacccata aagcgccaaa gactttaagc gtttaaaaat
    51961 cccctcctga ggaatcgcaa cgtcaaactc tctacgcttc caagatagcg acaagagcac
    52021 atcaaaaaag cgaaacttct tatccagtaa cgggtgaggc gtttgttgct ttttgatcga
    52081 aaagataaag tcatgcacaa tatccagatc atggtcagtc agctcataga tgacaatccc
    52141 gtacttatca tgcaataaag caatcaaata gcggatacgc cactcctcac caacaacact
    52201 attatcctcc aaggccaagc cgcactcctc aacaaagggc ttcatgtgct gaatcagccg
    52261 ataagctgac ggtgtggaaa taaaatgctc cctagcaaag cctgagacag atttgacctt
    52321 gtagtaaggt gccttgatca agagaaattt aagaatgtgc agccgtaccg attggcggta
    52381 aatcgtcttc aaaaacggct tgcccctttt caaaacggtg cagcggacaa tagtgctatc
    52441 ccactcaaaa gcaatatctc cttggaaaag ctcctctaat tggtggatat agcgctttat
    52501 gttagctagg ctaaagcctg ttttttgctg aatggcgtgg aaactgatcc tttttttagc
    52561 aagtagtatg gtcagcagca aagcctgatg attaatcact ggttccaaat acttttcaag
    52621 caaaacactt ttccctcctc aaaccatttt gttagcgtca ttatcataac agttttcacc
    52681 ccccaaaaaa aaaaagcgac aaaaaatatt taatatcagg actatttttc tgatagcctt
    52741 tattataaca caaaaccttg agccaggtaa aacgataaag aaatcaactt aaaactatta
    52801 cacattctca tctcatatga tatagttatt caggtttcct aatgggaaac acattaacaa
    52861 cttaatacat ggagagaaga gagttgaaaa caaaatcatt tagaaaggta ctgacgacgt
    52921 cagctacctg tattgtgctg gcaacaagct ttgccggagg aaccctacgc gtctgggcag
    52981 agcagtatta tgggtggact gatataaata gcagggcaga atcaccattc tttttgtatg
    53041 taacacctaa aaacaatcca aagcgtgaat taaaaaatgc atatgttgtt tattgcttta
    53101 atcgggataa aaagtggcca gctaactggg aagaagttaa taactataga aaacctaatg
    53161 aactagattt acctatttac gataaaagaa taggaacaaa tcaattattc atcaaagaag
    53221 cttctcatcc aagacttaaa atagatatgg aaaaatcctt agtagcaatt ttaagtaaag
    53281 gcttccccaa taatagtaca gaactgattt ccaaatataa gcttgataat aattctgcta
    53341 gagtagttac acaactagca atctggtatt ttagtgatag tgtgaatgat cctgaaagcg
    53401 tactcaggca gagattaaaa gaaaatgaat cgcaagcatt aaagtatctt atttcagtcg
    53461 gagaacaccc tcaattaagt caagctgagc aaaagcagac attagatata tatgtttaca
    53521 attcaggagg atattatgga aaagattatc aaaatctcct tggctctagt ttggttccta
    53581 aagaagaaaa gccttcttct gaatctgtaa ctcagagtaa tcttattcta cttgaacaaa
    53641 ataaccattc tgatatcatt tcaggtggtt caggaaatac tgaaactgag gaagatactc
    53701 ctcatctaat ggggatcggc ggcggtctag ctggcgaatc aggagaaact gcacctaaac
    53761 caggagaaac tggcggacac tcccctataa ttgaagaaaa ctatggtggt actgaagaat
    53821 ttcatgggaa ttcagaaatt attagtgaaa ccgaagatac taatcctggt atcatactag
    53881 gcggctcagg aaatgtcgaa acgcatgaag atactaggaa tcctcatcta atggggatcg
    53941 gcggtggtct agctggcgaa tcaggagaaa cgacacctaa accaggagaa actggtggtc
    54001 atggaccaat catcgagaca acagaagaca ctcagcatgg catatctggt aactctggtg
    54061 gtgcaataga atcagaggac actaagaagc ctgaggtctt gatcggtggc caaggacaaa
    54121 ccatcgaaac aacagaagac actcagcatg gcatgtcggg taactctggt ggtgcagtag
    54181 agtcagaaga cactaagaag cctgagatct tgattggcgg acaaggacaa atcatcgact
    54241 tctctgaaaa cacacaatca ggtatgtcag gacagtctgg agacactacg gtcattgagg
    54301 ataccaagaa gtctgagata atcattggtg gacaaggaca aatcatcgac ttctctgagg
    54361 atactcagcc gggtatgtct gggcaatctg gaggcaccac aattgtcgaa gacaccaaga
    54421 agccgacacc taagcctaaa cctgcacctg cgccaattgt taatgacgaa aaacctaaca
    54481 aaggcactca gctcccacag acaagtgata tgaagcaact caccctaagc atcatcggta
    54541 caatgtcaat gctacttgtc ctatgtcttt cactgttcaa gcgaccatct aaaaaagact
    54601 aagctatact gacaaatgat cattattgta aggacgttta caggcgggca tcatgccctc
    54661 ttgaaacacc gtacaacagc aaaaggtcta aatcaaatat ccctcaaggg ttagacaatc
    54721 gctctagccc ttgggggctt tttttgatac ttataataga agagagcaag cagtgacact
    54781 ttctttttgc cttatatctg ctaacactag cggtatgtgc agttaccata ggctatcaac
    54841 tcgtcgtgca actctagaga aaagctgata caaaaaacaa gcaccagcct tgctgctgat
    54901 gcttgctccg gacttactga taagcctttg tgatgtccta gctttataac catatgccta
    54961 ttacttgaag gtctaggctc ctaatggtgg gctggctggt aaaagcaagg agaaacagct
    55021 cccctttcca agctggctct caacagcaat atccccacct agttggcgag ctaactgcct
    55081 agcaatagag agccccagcc catgaccacc agtcttcata ttgcgagagg tctcaacacg
    55141 atacaggcgc ttgaaaatca aaggcaggtc ctcttttttg atcccttgcc cctgatcaat
    55201 aacatcaatg cgaatggact gctcctgttg ataagcatga atagtcaaag ccgtattagc
    55261 ctttgaatat ttaagcgcat tgctgactaa attcagcata atccgagaca aagcatcgta
    55321 tcggctgttg attttaacca cctcttttgc cacctcaata tgaacggagc gattttcctg
    55381 ctctaaggtc aattgaaatt ctgatagcat atcaatcaat agcttttcaa gatagatgat
    55441 ttgaagttgc tgcttgtcgt cttgcttttg atcatttaag ctgaccatat gcaattcttc
    55501 aactaattga ttcaaacggt tggtctgtcg tgagatggtg tttagatagt gcctctcctc
    55561 ttcccttgga ataacgccat ctaaaatccc ttctacagtt gcttgaatag aggtcaaggg
    55621 tgtcttaata tcgtgcgaca gctgagcaat catcatggat ttctcatgct cactctcact
    55681 caatgactca aagctgacct tcagctctga ggacatctga ttaaaggctt cctccagatc
    55741 tttaaactcc aaaggacact tgatgagctg accactatca aagtttctct cagaaatagc
    55801 ctgtatcttt ttctttagcc ttttaagcga tgaaaaaaca ttactcaaaa ggatcatatt
    55861 cacaattcct cctgctactg aagcaattag agctattact aaaatatatg aaatatcctc
    55921 aatggtaatg agcatttggt ttaacccaac aatcaggcct gcaatagtaa tcagcataga
    55981 cattaaatag ccaatgacaa tgtacgttct taatcgcatg ctacccctct aatttataac
    56041 ctagtcccca aaccgtttta atggttggtg tttgctcggt actgtatttt gccaagtcat
    56101 tgcgtaggga atgaatgtga acatttaagg tattggtatc atctaaatac tcctcctccc
    56161 atacacgctc ataaagctct gtttttgaaa agacatgatt caaatgattg gccaaaatcc
    56221 acaacaaatc aaaagccttg ttggtcagat taaggtcttg attggctacc gtcaccctcc
    56281 gggtgctatg atccatgacc aaatccccaa taactaagga gtcagcttgg ttagccttgc
    56341 cataaatccg attcaaaata tttttgaccc gtaagactaa ttcccgtgga ctaaagggct
    56401 tagaaataaa atcatctgct cccaagctca aagaataaat cttgtcaggc tcagatgttt
    56461 ttgcggtgat aaagagaaag ggctgatctg gcttttccag taaaacctcc ccaataaaat
    56521 catagccatc catattgggc atcatgacat cagtgataat caaatcgtac tgatccttat
    56581 gaaaaagctc caaggcttga ctaccatcgc ttgcagtggt aacacgatac cctgcctgct
    56641 gcaaataacg ttcgttaata tcaataattt ccaattcatc atccaccaat aatatcttgt
    56701 aggtcatgct tcctccttga ttaaaaaatt agtgctacac tctctcaagt ataacactaa
    56761 ttcttaactt agccaaataa ttctaatctc attaactcat caatcatttt aatcgtcgat
    56821 tgtgcacctt aatcatctta gatgcttaat aatcgcgcgg ataagtaatg cttgagtttt
    56881 gattgagaat accgtagatt gagcctctca catagtctgg cagttctagc tgttgagcat
    56941 cttggtcagt gagctgtgga gctgcagggg gttgtggagc ttctgactgc tctaaaccgg
    57001 ctatatcctt tggataagta acacttgagt tttggttgag aataccgtag attgagcctc
    57061 tcacatagtc tggcaagtct agctgttgag catcttggtc agtgagctgt ggagctacag
    57121 ggggttgtgg agcttctgac tgctctaaac cggctatatc ctttggataa gtaacacttg
    57181 agttttggtt gagaataccg tagattgagc ctctcacata gtctggcagt tctagctgtt
    57241 gagcacgttc gtagatctcc tgatcagtta agcgttgagt cgctggctga tcattaccag
    57301 catgggtaga agcagagaca gccggtgctg agcctagagc tagaaaggct cctccagcaa
    57361 acattgctga agtaagacca agcttcaaat aacgagctgc tagagttgtc tttgattgtt
    57421 ttgttgtagt cattgttgtc ataacgatta cctctttctt tttgttattc atgttatgga
    57481 ctaagtatag caatcaaata taaagtaaga ttaatctaaa gttaaattaa ttcttaagtt
    57541 attattataa aaatgtaaac tgataacttt tttaatcgct cctgatgtca aaccacctaa
    57601 aacaacacta acgacagcct cacacaagct catcacaaaa acaagcacca tctataaagc
    57661 tcaacaagaa aactctattt aaaggaaacg acctgttcgt tagtcgctag cacatcaaaa
    57721 cattgcaggc tagcatgggc ttttcattaa ctttaaaagg tcacatgttt gaagtcttgt
    57781 ctgatatgtt ataatagtta agtatcaaaa cttaggagaa ttagaactta tctgaaatta
    57841 ttcaaataaa tttaaatcaa cgttcctaaa atctattttt taaataagct taaacaaatg
    57901 tcgattcctt acctcataac tgccccctga gacatctttt aatgcaactg attaaaatca
    57961 aaaatatccc ctttgacact gctcaaaggg gatatgtgct atacttgcaa ttcctcgcgg
    58021 atagcttttt gcaataattg gctaaaattg attttgttct cttttccgac ttccacaagc
    58081 cagcttggta gtgtgacagt cttattgaca atcttagatc gttcgcgctc acgaacaagt
    58141 tcagtatcaa ctgaaattgc ctgaatcaca tcttcatcac ttgctaggtt acttgcaagt
    58201 gctttgaatg atgatggctt aggaaatttt ttgccttcgt cttcaaacat gatggcatag
    58261 atttctagga cttcacgagc gttatatata gcctcattca aagtattagc ttcgctgatt
    58321 gctccgggaa agtctgggaa agtaatggta taaccgccgt tttctctgtc tgcttcaaaa
    58381 agcgctagat aagtgtactt cataatgcga tagttagcta atgactaccc taaaatggaa
    58441 gaggtaggtt ttatccctac tttctattta gaacttttag cactgattgc aaggttttag
    58501 gtttatagtc tttttgcttt gggttactaa ttaggattgt tcgaccatct tcatgttccc
    58561 aaagcacgtg cgagcctttg cctttatcag ttggcctaaa acctttttcc ttcgccagtt
    58621 tctcaagttc cctacgcgtg gtcaccagct tcctcctttc ctttatttaa ttatattata
    58681 cacttgtttt aaacacttgt cgacaaaaaa tacttatttt taaactattg aagtccatta
    58741 taaaaatcgt tca
//
LOCUS       DARYSY010000004        56833 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYSY010000004 DARYSY010000000
VERSION     DARYSY010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56833
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            468..683
                     /locus_tag="TVR04_000180"
     CDS             468..683
                     /locus_tag="TVR04_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1268900.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKISKVFNEPIEQVFSLVEDER"
     gene            680..1456
                     /locus_tag="TVR04_000181"
     CDS             680..1456
                     /locus_tag="TVR04_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1268901.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGVGLVLGGLVGFGLARFNILE
                     NGFPISEEDIITGIKWAMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVTIANNASYLGLTFPIYEAMLLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1525..2781)
                     /locus_tag="TVR04_000182"
     CDS             complement(1525..2781)
                     /locus_tag="TVR04_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1268902.1"
                     /translation="MMTRLITFLTWTLWLVVAGVIAGVVAYVLTQAIHFIQALSFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWS
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINTPAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIIEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLIPPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLKNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2866..3825)
                     /gene="nrdF"
                     /locus_tag="TVR04_000183"
     CDS             complement(2866..3825)
                     /gene="nrdF"
                     /locus_tag="TVR04_000183"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1268903.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNLFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSDSEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(3998..6157)
                     /gene="nrdE"
                     /locus_tag="TVR04_000184"
     CDS             complement(3998..6157)
                     /gene="nrdE"
                     /locus_tag="TVR04_000184"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1268904.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFAENVI
                     PNTMSFSSVNEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIEAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNDDMYLFSPYSVEKEYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIKAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGTYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQSVM
                     ADGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6178..6396)
                     /gene="nrdH"
                     /locus_tag="TVR04_000185"
     CDS             complement(6178..6396)
                     /gene="nrdH"
                     /locus_tag="TVR04_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1268905.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETDQVVFSGFQPAKLKDII"
     gene            6818..7081
                     /locus_tag="TVR04_000186"
     CDS             6818..7081
                     /locus_tag="TVR04_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1268906.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7086..8819
                     /gene="ptsP"
                     /locus_tag="TVR04_000187"
     CDS             7086..8819
                     /gene="ptsP"
                     /locus_tag="TVR04_000187"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1268907.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFEEEKASLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9021..10448
                     /locus_tag="TVR04_000188"
     CDS             9021..10448
                     /locus_tag="TVR04_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1268908.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERAAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAISEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDKVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTSNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11101..12315
                     /locus_tag="TVR04_000189"
     CDS             11101..12315
                     /locus_tag="TVR04_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1268909.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSMTLFQPSEFMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTRSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12411..12980
                     /locus_tag="TVR04_000190"
     CDS             12411..12980
                     /locus_tag="TVR04_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1268910.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKESTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKDKYLISQGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            12981..14933
                     /gene="gyrB"
                     /locus_tag="TVR04_000191"
     CDS             12981..14933
                     /gene="gyrB"
                     /locus_tag="TVR04_000191"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1268911.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASYIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15082..16806
                     /gene="ezrA"
                     /locus_tag="TVR04_000192"
     CDS             15082..16806
                     /gene="ezrA"
                     /locus_tag="TVR04_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1268912.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     RTRERIRF"
     gene            17175..17456
                     /locus_tag="TVR04_000193"
     CDS             17175..17456
                     /locus_tag="TVR04_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268913.1"
                     /translation="MKVTKALCALAAAATLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17639..18094)
                     /locus_tag="TVR04_000194"
     CDS             complement(17639..18094)
                     /locus_tag="TVR04_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1268914.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18085..18231
                     /locus_tag="TVR04_000195"
     CDS             18085..18231
                     /locus_tag="TVR04_000195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268915.1"
                     /translation="MSPYQSFQAYDTVIILLTAPNTNDKAFDRLLEEDEIKEKQHENN
                     SLIS"
     gene            18315..19622
                     /gene="eno"
                     /locus_tag="TVR04_000196"
     CDS             18315..19622
                     /gene="eno"
                     /locus_tag="TVR04_000196"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1268916.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19758..19994)
                     /locus_tag="TVR04_000197"
                     /pseudo
     CDS             complement(19758..19994)
                     /locus_tag="TVR04_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20204..20425
                     /locus_tag="TVR04_000198"
     CDS             20204..20425
                     /locus_tag="TVR04_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1268917.1"
                     /translation="MGTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKLYHQAYAEYKADPETISHADFKKELGL"
     gene            20427..20687
                     /locus_tag="TVR04_000199"
     CDS             20427..20687
                     /locus_tag="TVR04_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1268918.1"
                     /translation="MYHIEYSKKAQKQIKKLDKQIQRLLFAWIDKHLEGTDNPRANGK
                     GVAGNHANEWRYRIGDYRLICDIQDDKMVILALEFGHRRDVY"
     gene            21798..22403
                     /locus_tag="TVR04_000200"
     CDS             21798..22403
                     /locus_tag="TVR04_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1268919.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLASKGCQRPKWSHQLERLFADTKPCLQVLSKTYQLGIIANQAKGLK
                     ERLERFGISHYFALIVSSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKTLGMTAIRIHQGLAASSPDDRLYPSDVHISKLSDLLKCF"
     gene            22883..25663
                     /locus_tag="TVR04_000201"
     CDS             22883..25663
                     /locus_tag="TVR04_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1268920.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPAAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGNGFYIQDSQGTGLYIYPGSSLGYATGDVVQLTGTLTN
                     YKGELQLKDVTDHKKVEGDLPTPVAEVTIPDLKQAHPSTLVRLSNVTVGDISSDKHET
                     SSFKVTDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFNL
                     DQFEVVKKAVREEEITPRGQVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRMLTNSGGILLPETGYNTDLIPVLFKYGKQTIKAGD
                     SYKGRLTGPVSYSYGNYKVFVDDSSHMPVLTDGQLKPEKTQIKKDPSKLSIASYNIEN
                     FSANPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDARQSAQRLID
                     AIKALGGPTYQYVDIAPENNADGGQPGSNIRTGFLYQPERVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWKSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHDRSDRYSYFYRGNDQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSHQPGTRPAPAATAKPAKAARAQLLPKTGDKAGLVISILGLTAVFS
                     SFSLFRKRQERK"
     regulatory      26350..26469
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            26467..26973
                     /locus_tag="TVR04_000202"
     CDS             26467..26973
                     /locus_tag="TVR04_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1268921.1"
                     /translation="MTSFTVRDYVHIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            27070..29028
                     /gene="ligA"
                     /locus_tag="TVR04_000203"
     CDS             27070..29028
                     /gene="ligA"
                     /locus_tag="TVR04_000203"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1268922.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGGTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGILKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRKAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLEAADSQQRTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEATREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRSNQTPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLIQRSLEHFASRQAMAIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHVGA
                     KASRLILETYGDLETLLSVTAEELAQIDGLGLVIGQSLVQYFQQDQAAQLLAELKSAG
                     VNLAYLGQRPDRQAELFGLTVVLTGKLEKLNRTQAKEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIENEDWLLNL"
     gene            29041..30063
                     /locus_tag="TVR04_000204"
     CDS             29041..30063
                     /locus_tag="TVR04_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1268923.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGVFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPMTLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            30072..32372
                     /gene="pulA"
                     /locus_tag="TVR04_000205"
     CDS             30072..32372
                     /gene="pulA"
                     /locus_tag="TVR04_000205"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1268924.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWHYQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHYGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     FYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLKPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPIFDHHQ
                     FFDDNGGYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMIDSILYW
                     TNEFNIDGFRFDLMGLHDIETMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKE
                     NASQMPGIGFFNDDQRNAVKGAEVYGSFEKGFVSGAPTEGLVAKSILGSDELVSYGTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGVYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETIAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHADENTGFISFTVEDERKYRLIFSNFRNRLQSPANHVII
                     ETNDKRFHDSESMLDELTAMILDITQ"
     gene            32518..34398
                     /gene="glgB"
                     /locus_tag="TVR04_000206"
     CDS             32518..34398
                     /gene="glgB"
                     /locus_tag="TVR04_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEL1268925.1"
                     /translation="MDNDLALYTFGTGENFHIQDYLGVHRINNDTGTSYVFRVWAPNA
                     EAVSLIGDFTDWQSNPLEMTRNEAGVWEVTTSLPQEGDIYKYWVRRQGGQLVEKIDPV
                     AFLFEARPGTGAIVKTLPVKKWRDSLWLGRRKRFGFRQRPVNIYEVHAHSWKKDENAR
                     PYDFSKLKEELIPYLKSMHYTHIEFMPVMAHPLDMSWGYQLMGYFAFESTFGSPEAFQ
                     DFVEACHLNNIGVLIDWVPGHFTQNDDALAYFDGTATYEYQDHHRAHNYGWGALNFDL
                     GKTQVQSFLISSALFWLEAYHVDGIRVDAVSNMLYLDYDQGPWTPNQYGGNQNLEGIA
                     FLQKLTTVIKEKHPDVMMIAEEATSATPITSPVAEGGLGFDYKWNMGWMNDILRFYEE
                     DPYYRKYDFNLLTFSFMYCFKEHYILPFSHDEVVHGKKSLMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEFGQFLEWKYDHQLEWQNLEDELNAKMQHFTASLNQLYKDH
                     SMLWQNDETYDGIDIIDADNKDESVLSFCRQNNKGELLLCVFNMTPVERPGFTIGVPI
                     AGLYQEIFNTELEAFGGVWKEHNPLTSTVAKKWKTYPQTLSFTLPALGASIWKIKRRQ
                     KQ"
     gene            34465..35604
                     /locus_tag="TVR04_000207"
     CDS             34465..35604
                     /locus_tag="TVR04_000207"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1268926.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVVIDGSKDVQVVGYNEVVGVPNED"
     gene            35594..36727
                     /gene="glgD"
                     /locus_tag="TVR04_000208"
     CDS             35594..36727
                     /gene="glgD"
                     /locus_tag="TVR04_000208"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1268927.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYHQILTYLRRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVQRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRIASQARVANSILLPKAVIGE
                     GAVVEHAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            36724..38154
                     /gene="glgA"
                     /locus_tag="TVR04_000209"
     CDS             36724..38154
                     /gene="glgA"
                     /locus_tag="TVR04_000209"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1268928.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDAGMLGDLFGVGMERYEDGTLRWHDGLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGKGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPAPFSAKDLSGKAA
                     TKQALQERLGLAVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQHIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            38173..40569
                     /locus_tag="TVR04_000210"
     CDS             38173..40569
                     /locus_tag="TVR04_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1268929.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTDQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGLQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQTIENTRIVKDNQIYMAHLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIVKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDASLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFINGTIPNSQHEGMEIYEALITHNDEY
                     FLLEDFSSYVKAQAKIDQLYRQKDKWSKMSLINIAHSDKFTSDDTITQYAKDIWRLKR
                     "
     gene            40911..41108
                     /locus_tag="TVR04_000211"
     CDS             40911..41108
                     /locus_tag="TVR04_000211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1268930.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            41142..41858
                     /gene="atpB"
                     /locus_tag="TVR04_000212"
     CDS             41142..41858
                     /gene="atpB"
                     /locus_tag="TVR04_000212"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1268931.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            41876..42370
                     /gene="atpF"
                     /locus_tag="TVR04_000213"
     CDS             41876..42370
                     /gene="atpF"
                     /locus_tag="TVR04_000213"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1268932.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAILQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            42370..42906
                     /locus_tag="TVR04_000214"
     CDS             42370..42906
                     /locus_tag="TVR04_000214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1268933.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            42922..44427
                     /locus_tag="TVR04_000215"
     CDS             42922..44427
                     /locus_tag="TVR04_000215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1268934.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFEIIRTTKDLPQEAELDAAIQAFKAQSNFK"
     gene            44445..45320
                     /locus_tag="TVR04_000216"
     CDS             44445..45320
                     /locus_tag="TVR04_000216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1268935.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            45488..46894
                     /gene="atpD"
                     /locus_tag="TVR04_000217"
     CDS             45488..46894
                     /gene="atpD"
                     /locus_tag="TVR04_000217"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1268936.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            46907..47323
                     /locus_tag="TVR04_000218"
     CDS             46907..47323
                     /locus_tag="TVR04_000218"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1268937.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVGEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDINEVQRAKVALRRALNRINVSKK"
     gene            47457..47693
                     /locus_tag="TVR04_000219"
     CDS             47457..47693
                     /locus_tag="TVR04_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1268938.1"
                     /translation="MEVIRNLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            47757..49028
                     /gene="murA"
                     /locus_tag="TVR04_000220"
     CDS             47757..49028
                     /gene="murA"
                     /locus_tag="TVR04_000220"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1268939.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGKTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            49032..49220
                     /locus_tag="TVR04_000221"
     CDS             49032..49220
                     /locus_tag="TVR04_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1268940.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLVIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            49252..50130
                     /locus_tag="TVR04_000222"
     CDS             49252..50130
                     /locus_tag="TVR04_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1268941.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKLVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYNHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRRALDSNKRVRYRVTLLYDGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVAPSQH"
     gene            50144..50302
                     /locus_tag="TVR04_000223"
     CDS             50144..50302
                     /locus_tag="TVR04_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268942.1"
                     /translation="MVKADHSASHHGREALVLVAPQRKVLTIFGLVALAEKQIGPLVE
                     APSMSAPG"
     gene            51042..52085
                     /gene="pheS"
                     /locus_tag="TVR04_000224"
     CDS             51042..52085
                     /gene="pheS"
                     /locus_tag="TVR04_000224"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1268943.1"
                     /translation="MDLQAQLEELKTKTQEALQQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            52275..54680
                     /locus_tag="TVR04_000225"
     CDS             52275..54680
                     /locus_tag="TVR04_000225"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1268944.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHVVSCDAIPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKATEITTSS
                     KTVVLEAAVFNGKSIRKTSSRLNLRSESSSRFEKGINHDTLIEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSSSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKEALPTELNHFAFAITGLVADKDFQTPAQAVDFYHA
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGATIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            54915..55991
                     /locus_tag="TVR04_000226"
     CDS             54915..55991
                     /locus_tag="TVR04_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268945.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIVKGKLADYPKADL
                     QQLAIKDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILAAMV
                     IFAVLGTLFSVFTIVRIDPLEAIG"
     gene            56001..56690
                     /locus_tag="TVR04_000227"
     CDS             56001..56690
                     /locus_tag="TVR04_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1268946.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKQTDFSIEAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSRLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKNKQKAKRQQLFEDLGITKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDSHHTHPQN"
BASE COUNT        16088 a        11010 c        13381 g        16354 t
ORIGIN      
        1 cagtagattc tagctatatc acaggtgaga tagtaatgat cgtgcaaaac aataaactga
       61 tttttccacg tgggatattt gttatcagtg ggttaagtag aactagcagc tattgtttta
      121 ttgctagtca tatagtgttt tgaaggtgcc tattttctgt tacaatagtg atgacaacag
      181 gttaagctaa gttcggtgga gcttggtttt ttattgttac aagaaacctc atagattgta
      241 attatattct tttataatat gacaatatta atactttttg acaaatattg ttgtcaaaaa
      301 gtaaatgatc tgttacaatg aagttagact catgaaagaa aaaagtaatc agtaggataa
      361 caataacaaa gctattttaa gcttatacca ttgtgtcaat ggattgttgc tggaaatgac
      421 tggtgctttc tgttcaatca ggagacagca tttattagga gtgaagcatg gcttataggt
      481 tgagaaatcg gctcaaggag ctacgagcta gagatggcat taatcagacg cagatggcag
      541 cattagcagg tgtttccaga cagaccatta gtctcattga gcgaaatgaa tacacaccat
      601 ctattattat tgcaatgaaa atttctaaag tatttaatga accaattgaa caggtattta
      661 gcttagtgga ggacgagaga tgaaagcttt tatgacggaa aaggacagta cgttggtgag
      721 aatacttaag tcattactgc ttggatcagg ggttggctta gtgttaggtg gccttgttgg
      781 ttttggttta gctaggttta acatattaga aaatggcttt ccaatatcag aagaagacat
      841 cataactgga ataaagtggg caatgagacc ccttgttatc gtgcttatgc tactgagcat
      901 ttatgatatt tatcaagttg tcaaagaata tgccagatat gtcaagctaa gcgatgatga
      961 aacagaggag ctgtatcgtt acattaacct taagcatgcc tatgctttag gatttagtgc
     1021 tatggctatg gtcttgaata tagtcgtttt ttctttggga tatagggtga ctattgctaa
     1081 caatgctagc tatcttggtt tgacttttcc tatttacgag gctatgctgc ttgtggttat
     1141 tagtgttctc catgcttata ttttgaaggt ttatactcgg attcgcgggg tcaagatgac
     1201 gcttgctcct accttaaagg aattaaagca gaatatctta caacaggacg aggcagaatt
     1261 gcaggctaat tatcaaatgt cttttgaggt tgtcatgggc cttagtggct ttatattacc
     1321 aggcatttac gtaatattat tgcttttatc tatgattttt caaagggttg agctgaccgg
     1381 actaatcatt actgctagta ttcacctcta tattctggtg aaatccttta aatcagcaca
     1441 tgatttttat aggtaaggcg taaggtttta cctactcaag aattgttata cagcaaaaaa
     1501 gctttgataa gccattactg gcgatcaaag ctttttgtgt ttgttgaaaa agaggctttt
     1561 ttgaaagagc tgttggctga gatagcttgt caaacctaca attgcaagcg gcacaaggct
     1621 aatgagaggt tgtccggtaa tttcaatgag aaaaagagga gcagtaagag gtatctgatt
     1681 aatgattccc aaaaagaggg tcgctccaat gacaatggcc aagggaagtg gtacagagag
     1741 ataacctagc tgattgctaa ggcttgccag tagcaagcca ctagctcctc caagcatcat
     1801 agaaggagca attttgcctc ctttagctcc agaggcaaat actgcataga cagcagctgc
     1861 tttacttagt aagagcgagg cggtataaga taggctgaca tcatggtgta gcagcaggag
     1921 gagaccggcc ttgccattgc ctaaaatctc tgggaaataa aggcttaaac aagcactaaa
     1981 gccaaaagct cctaagacac gagggataaa ccatcggctc ttaggctttg cctttggtgc
     2041 gtttttgagc agctgctggt agcaaaaggc cagaaatgct aagatgggac tggcaatgat
     2101 agcccaaagg actgttgtca attgccaggc ttgcggggga atgagatact gtatgtcctg
     2161 atgtccgctt agaacaagca cactctgaac agcagtgaaa gcagttatag ctgctgcgta
     2221 gatgtgttta actgagcatt ttttgacaat agcctctatg ataaagacaa ttgtagctag
     2281 tggtgcctgg tagacagctc caagggcagc tcctgaagca caggctaaaa gcaacccttg
     2341 ctctgctgct ggggtattta tagctttatt gcatgcggca gtcagtgcca cagcaacctc
     2401 acgtgaagca ccttcacgac cgacaggtgc tcccatagag acggttatta attgcagcca
     2461 gccatgacaa aactgggacc aagggctgaa gtccttttgc tgactgagtg tttgttggat
     2521 aggttgaata ggcttggctt ttttagcaag cagctgccaa ccgagaccag caatagctcc
     2581 agccaacaat agagataaaa agcgcctttc tggagctacc gttgcaatca tggtgctaaa
     2641 ggagccagat tggtagccaa agctaagagc ctgtatgaaa tgaatggctt gagtgagcac
     2701 gtaagccacc acaccagcaa tcacaccagc taccactagc cagagcgtcc atgttaagaa
     2761 agtaatcaat cgagtcatca tatcttttat tatagcagat aaaaagaacc tgagactact
     2821 caggctccaa aatatagaca aatccaatct tcatgagaag ctggactata gtccataatt
     2881 gtaatcgtca tcagtcatag cttcaacggt gccaagaagg tagccgttac caacctgaga
     2941 gaagaaatcg tggtttgacg tgccagttga aatgccattc ataacgattg ggttgacatc
     3001 attggcagtg tctggaaata gagggtcctg accaaggttc atcaaggctt tgttagcatt
     3061 gtagcgtagg aaggtcatca cttcctcggt ccagccaacc tcatcataga gggtcttagt
     3121 gtattgctct tcattttcat atagctggta cagcaggtca tacatccagt cacgaaggct
     3181 ttcttgctca ctgtctgata gttcattaaa gcccagctga aacttgtagc cgatataagt
     3241 gccatgaacg gactcatcac gaatgatgag cttaataatt tcagcgacat tagccagctt
     3301 attgttgccc agataataga gtggtgtaaa aaagccagaa taaaagagaa aggtttcgag
     3361 ataagttgag gctaccttct tttgaagggc actgccattt tcataaatgt cgttgatgat
     3421 cttagcctta ttttgaagaa ataggttgtt gttggtccac tcaaaaatgt cttcaatttc
     3481 ttttttggtg tttagggtcg aaaagattga tgagtaggat ttagcatgga cagactccat
     3541 aaattggata ttgttaagaa ctgcctcttc atgcggggtg cgcacgtcct tgcggatggc
     3601 ttcgactcct gactcagact gcatcgtatc aagaagggtt agcccgccaa agaccttacc
     3661 tactaaatcc ttttcaacag cagataattt gcgccagtca tcaaggtcat ttgacagtgg
     3721 aatacgtgta tcaagccaga attgctccgt cagcttttcc caggttgact tgtcaatgac
     3781 atcttcgatt tcattccagt tgattgcttc atagtatgtg gtcatgggtt tctccgatag
     3841 attgtaatat agggttaggt agtgctagga ggagagcctt gagtgctggc tttagcgcca
     3901 gctattttgc tgtgctggtc tatccttagg acaggtgcac caacatcagc tggatactga
     3961 catcaaggac tggttcacct tactgcaact cacttggtta gatgacgcag ctttcacact
     4021 gattagctcc gacttcctca ccgtcatcgg taaaggttcg gatataatag attgatttta
     4081 tccctttgtt aaaggcgtaa tgtctcaaaa tcgataagtc acgagtggtt tgcttgcttt
     4141 ctgttttcca ttcgtagagc tcctttggca attcgctgcg caaaaagagt gttaacgata
     4201 gcccttgatc aacatgcttt gtagcagctg catagacatc aatcaccttt ctcatatcca
     4261 tatcataggc agatgtgtag taaggaatgg tatctgtaga taggccgttg gctgggtaat
     4321 aaatcttacc aattttcttt tcctgacgtt cttcgatccg ctgagtaatc gggtgaatcg
     4381 aagcagagca gtcgttgata taggaaatgg atccattagg agcaactgcc agacggtttt
     4441 gatgataaag cccatcagcc ataaccgatt gacgcagtgc tttccaatct gctgcttgcg
     4501 gaataaagtg atccttgaaa agacttttaa ccagctctga ttttggcaca cattctcctg
     4561 tgatgtattg gtcaaaataa gtgccgctag catacgttga tttttcaaag ccaacaaagg
     4621 ttgtctgccg ctcgcgagcg atctgattgg attcgacaag cgtccagtaa ttcatcagca
     4681 taaagtaaat atcagtaaat tcgatagatt ctggactgcc atattcgata tggtgctgag
     4741 ccaaatagga atgaagcccc atagccccaa ggccaaaggt atgtgcttga ctgttaccat
     4801 ttttaacggt tgggactgct tcgatattag aggagtcagt gacaaaagtc agggcacgtg
     4861 tcatagcttt gatggaacga ccaaagtcag gtgacgtcat catgtttaag atattagttg
     4921 atcccagatt gcaggaaata tcagttccca ttttgacgaa ctcctgcgca tcattaatga
     4981 gactaggcgt ttgaacctgt agaatttctg agcataggtt gctcatgatg attttaccgt
     5041 caatagggtt tgacctgttg gcagtgtcga tgttgataac atatggatag ccagattcct
     5101 gctggagctt ggaaatctcc gtctctaaat cacgtgcctt gattttcgtt ttggtgatat
     5161 tgggattggc aaccaattcg tcatacatgc tagtaatgtc aatgtagtta aatggtaggc
     5221 cgtattcttt ttcaacgcta taagggctaa aaaggtacat gtcatcattg tgacgggcaa
     5281 gctcatagaa tttgtctggt acagtaatac caagtgacaa tgtcttgacc cgcacctttt
     5341 catcagcatt ttcttttttg gttgacaaaa aagcgataat atcagggtga aagacgctta
     5401 aatacaccac accagcccct tggcgctgcc ctagctgatt cgaataagaa aagctatcct
     5461 caaatagctt cattacaggc acgacaccag aagcagctcc ggcatagccc ttgattggag
     5521 cgccagcctc acgaaggttg gataggctaa tgccaacacc acccccaata cgggataatt
     5581 gcaaggcaga attaatagag cggccaatgg cattcatgtc atctgtcacc tgaaggagaa
     5641 agcaagaaac cagctcacca cgacggcttc gtccagcatt taaaaaagaa ggagtagcag
     5701 gctggtaacg ctgattaatc atttcaatgg ctaagtcctt agctaatgtt tcatcaccat
     5761 cagcaaagta aagggcattg aacatgaccc gatcctctat gctctctagg tagaaattgc
     5821 catcgttggt ttttagggcg tactgctggt agaatttata ggccgccata aatgatttaa
     5881 agcgaaagcc ctctgcctca atgctcttgg ctaggtggct aataaattca ggagaatagt
     5941 tttggataaa ggctgattca atatagtcat tgtccacaag ataggcaatc ttttcgttga
     6001 cagaagaaaa tgacatggtg ttaggaataa cattttcagc aaaaaaagcc tccaaagctt
     6061 ctttgtcttt gtgaagcgga atgctaccat caacaggacg gttaatttca ttgttgaggc
     6121 gaaaataaga aatatcgcca agatctttga gactcatatc aattgttcct tgtctagtta
     6181 aataatatct tttagttttg ctggctgaaa ccctgagaat actacctggt ctgtctcaat
     6241 aacaggagca gcagtaaagc caaggctctt aacataatcc actttttctg gatgctcatc
     6301 aatattaatc tcttggaaag cagctccatg ctgttctaaa aatttcttag tcattttgca
     6361 ctgcatgcaa ttgtgctttg agtatactgt aatcattgct cgtccttcca actattagtc
     6421 tttcactcaa ttttaggaaa aatcaaatga ctctaatagg atataaaaaa tgttcctaaa
     6481 aagcaaacga tttatttcgg aatagcacaa gatattgtgg ttgtgtgtga gaatatttct
     6541 aaatattgtg ttatcctctc ttatcactga taattgctac aagaggctta tagttcttaa
     6601 atgcatacta atcaggttgg aaggttcatt tgatgccatg aaaattgtga tgtaagaatc
     6661 attgatagtc tatgaaaatt caagaaaact gtttcatgat tttttcttgt tagaacattt
     6721 aaccttgaaa ataaaaaagc attgtgctat aatcacttat tgtaagggtt atcatgtgat
     6781 agctcgaaaa tacacaattc aaaaggagaa ccatattatg gcttcaaaag actttcacat
     6841 tgttgcagaa acaggtattc atgcacgccc agctaccttg ctagttcaaa cagcaagcaa
     6901 atttgcttca gatattacac ttgactacaa aggtaaagca gtaaatctta aatcaatcat
     6961 gggtgttatg agccttggtg ttggtcaagg tgctgacgta acaatcacag cagaaggtgc
     7021 tgatgcagat gacgctattg cagcaatcga agaaactatg actaaagaag gattggcata
     7081 agactatgac agaaatgctt aaaggaatcg cagcctctga cggtgttgct gttgccaaag
     7141 catatctgct agttcagccg gatttgtcat ttgagactat cacagtcgag gatacaaatg
     7201 cagaagaagc tcgccttgat gttgcattac aagcttcaca agacgagctt tctgttatcc
     7261 gagaaaaagc agtagaaagc ttaggcgaag aagcggcagc agtttttgat gcccatttga
     7321 tggttcttgc tgatccggag atgatcagcc aaattaaaga gactattcgt gcgaagcaaa
     7381 cgaatgccga aacaggtcta aaagaagtga ctgacatgtt catcacaatc tttgaaggca
     7441 tggaagacaa tccttacatg caagagcgtg cagctgatat tcgagatgtt gctaagcgcg
     7501 tcttggctca tttattaggt gttaagcttc caaatccagc tacaatcgat gaagaagcca
     7561 ttgttattgc gcatgatttg acgccttcag atactgcaca gcttaacaaa caatttgtaa
     7621 aagcatttgt aacaaacatt ggcggacgta cgagtcactc agctatcatg gcccgtacac
     7681 ttgagattgc ggctgtgctt ggtacaaatg atattactaa gcgtgtcaaa gatggtgacc
     7741 ttattgctgt taacggtatc actggtgagg ttattattga cccaagtgag gagcagattc
     7801 ttgctttcaa ggaagctgga gaggcttatg cgaagcaaaa ggctgagtgg gctctgctta
     7861 aggacgcaca aactgtcaca gcagatggca agcactttga attagcagca aacatcggta
     7921 cccctaagga cgttgaaggt gtcaacgata atggtgctga ggcggtaggt ctttaccgta
     7981 ctgagtttct ttacatggat tctcaagatt tcccaactga agatgagcaa tatgaagcct
     8041 acaaggctgt tcttgaagga atgaatggca agcctgttgt tgttcgtaca atggatatcg
     8101 gtggggacaa ggagcttcct tactttgatt taccaaagga aatgaaccca ttccttggtt
     8161 ttcgtgcctt acgtatttca atctctgaaa caggtaatgc catgttccgc acacagattc
     8221 gtgctttgct gcgtgcttct gtgcatggtc aattgcgtat catgttcccg atggttgccc
     8281 ttctaaagga atttcgtgct gctaaagccg tatttgaaga agaaaaggct agcttgctgg
     8341 ctgagggtgt tgcggttgca gacgatattc aggttggtat catgattgag atcccagcag
     8401 cagcaatgct tgctgaccaa tttgccaagg aggttgactt cttctcaatt ggtacaaatg
     8461 accttatcca gtacacaatg gcagcagacc gcatgaacga gcaagtgtca tacctttacc
     8521 agccatataa cccatcaatc cttcgtttga ttaacaatgt tatcaaagca gctcatgctg
     8581 aaggtaagtg ggctggtatg tgtggtgaaa tggcaggtga ccaacaggct gtgccacttc
     8641 ttgttggtat ggggcttgat gaattttcaa tgtcagcaac atctgtgctt cgcacacgta
     8701 gcctgatgaa aaagcttgat tcagcgaaaa tggcagagta tgctcatcgt gcactgacag
     8761 aatgctcaac tgctgaagag gttcttgagc ttgccaaaga gtatattaca gaagcttaaa
     8821 tagaaataac gaggagctgg ttttgtccgg ctctttttta ctagaaaaat gactaatcag
     8881 atccagatga aagcttgctt tataaagtag tttgatgttt caagttttat cagaattttc
     8941 agactcttcc tgtagcgaat tgttgaaata tgctaaaaaa gtgatagaat aatagtacca
     9001 ttataaaagg agaaaaaagt ttggctaaac aatataaaaa tttagtgaat ggtgagtgga
     9061 agctctctga aaatgagatc aagatctatg caccagcaac cggcgaggag ttaggtagtg
     9121 taccagctat gtctcgtgaa gaggttgatc aggtttatgc gtcagctcgc gctgctcttg
     9181 cagattggag agcgctttct tatgttgagc gtgctgctta tttgcacaag gctgctgata
     9241 ttttggtgcg tgatgctgag aagattggtg ctgttctctc aaaagaggtc gcaaagggtt
     9301 ataaggctgc tattagtgag gttattcgta cagcagaaat tattaactat gcagcagaag
     9361 aaggccttcg tatggaaggt gaggtgcttg agggtggcag ctttgaagcc gctagcaaga
     9421 aaaagattgc gatcgtacgt cgtgagccag tgggacttgt gcttgcgatt tcacccttca
     9481 attacccgat taacctggca ggctcaaaga ttgctccagc ccttattgca ggaaatgtcg
     9541 tggctcttaa gccgccgaca cagggctcta tttctggctt gcttttagca gaggcatttg
     9601 cagaagcagg tcttcctgct ggagtcttta ataccatcac tggacgcggc tcagttattg
     9661 gtgattacat cgttgagcat gaggctgtaa actttatcaa ctttactggc tcaacgccaa
     9721 ttggagagcg aattggtaaa ttagccggca tgcgtccgat tatgcttgag cttggtggta
     9781 aggattcagc gattgtccta gaagatgctg atattgcctt agctgctaaa aacattgttg
     9841 caggtgcctt tggctactca ggtcaacgct gtacagcagt taagcgtgtg cttgttatgg
     9901 aaagcgttgc agatcagctg gtagcagaga ttaagggctt agttgagaaa ttacttatcg
     9961 gtatgccaga ggacaatgct gacatcacac cattgattga taccaaagca gcagattttg
    10021 ttgaaggtct ggttaatgat gcagcagaca agggagcaca ggcgcttact gaaatcaagc
    10081 gtgacggtaa tttaatttgt cctattttat ttgacaaggt aacaactgat atgcgtttgg
    10141 cttgggaaga gccatttggt ccggtgctgc cagtgattcg cgtaagctct gtagaagagg
    10201 caatcagcat ttcaaatcaa tctgaatatg gcttgcaggc ctctatcttt acgtctaatt
    10261 tcccacaagc ctttgctatt gctgaaaagc ttgaggttgg tacagtgcac attaacaaca
    10321 aaacccagcg tggtacagat aatttcccat ttttaggggc caagaaatca ggagctggtg
    10381 ttcaaggggt caaatactca atcgaggcaa tgacaagtct caaatcagtc gtatttgata
    10441 ttcaataata aaaaagctag ggcatcttag tttgaaagca gtcgtacatt tgtgcggctg
    10501 ttttatttgt gtctctagtt ttaacagcta gctatgcaag aaggtgagtt gtcccaactt
    10561 caaagatgag atctaaacgt ttaatgattt tgaggtcgta aaaaagtcta gagtgttttg
    10621 atctcgttaa gatgtgaagg gacaaagcct cgctaacagc cagcagcacc agccattgag
    10681 gtcaaggaag ctgctaaaat agctgatggt tcaaaagctt ggtgaaaggc ttaatatcta
    10741 tcattgctat tttgagggct ttccattata atatgaatac tagagctact tgtcggtctg
    10801 cctcttgagc tgtgagatag ctgttggatt tagttgtctc cttgtccaca aaaggcttag
    10861 aggcaaaggc tgtggctatg cttcttgctt cttttagtga agtgtatgag atcttatgaa
    10921 aactcatata ggctttggta tctttgcaag aggactaatg gcttgcttta cttgccttga
    10981 tagagggctg ggattgaggg gtgatgacct gcggtggtca tctctagagc tccttgcttc
    11041 tttttttatg tagactaatg gtttagactg ctagcttcct tgtttagaaa gtaggacatc
    11101 atgttaccca agagaaaatt aattgatcaa cgtcttgatt atgccattat ttttcccgtt
    11161 ttttgcttgc taatatttgg tctggtatct gtgtatgtgg cggcgagtca tgattttccg
    11221 caaagcctcg ccactgttat gcttcaacag gttctctgga tccttcttgg agctgtgatt
    11281 gcctttaccc taatgttttt tagcacagag attctgtgga aattaacacc tgtcttttat
    11341 cttttgggtg tgctattaat ggttctgcca ctcatctttt ttagccctcg tctggtagct
    11401 gctacaggag cgaaaaattg gattacgatt ggctcaatga ccttgtttca accatcagaa
    11461 tttatgaaaa tatcctacat tctggcaatg tctcggttaa cggtctggtt taagagaagg
    11521 caggagagaa gtcggttttt agatgattgg aagctcttgg gcttatacct tgtcttgacg
    11581 ttgccggtca tggtcctgct agcactgcaa aaggacttag gaacagctat ggttttttta
    11641 gccatcttag ctggaattat cttaatttca gggatttctt ggtggcttat tttaccagcc
    11701 ttggtactag tctttttact ggtttcagct tttttctttg tttttttgtt gccagaagga
    11761 aaagaattcc ttttaaaaat gggaatggat acctaccaat tgaatcgtat ttcagcttgg
    11821 ctgacaccgt ttgatttctc agataccatt gcctatcagc agacgcgaag tatgatttcg
    11881 attgggagtg gtggcttttt tggtaagggc tttaatcagc ttgagctgtc ggtgccagtc
    11941 agagaaagtg atatgatttt tacagtgatc gctgaaaatt ttggctttct tggtgcagct
    12001 agcttactga tcttgtattt aatactgatt taccgcatgc ttagggtgac ctttgcatcg
    12061 aataaccttt tttataccta catttcaacc ggctttatca tgatgatact atttcatatc
    12121 tttgaaaaca ttggcgcagc agttggtctg ctacctttga ccggtattcc ccttcccttt
    12181 atttctcagg gcggctcttc cttgatttca aatctgattg gggtcggcct gatcctatca
    12241 atgaactatc agcacgtcct tgctcatgaa aagcaaagcg agcatgagct tagcagaagc
    12301 tcacgttatg tttaagaggc atgtttggtc cttgttcggt tagaatgagc tgccaatcag
    12361 ccctttttta tttgcttaat cgctataaaa ataaagaaaa atatgttata attaaggtta
    12421 tgaattatca tgattatatt tgggatttgg gcggcactct cttggataac tatgaaattt
    12481 ctacccaggc ttttattgag acgctgcatt tttttaagct gtctgcaagc cacgatgccg
    12541 tttatcaaag gcttaaggaa tcaacagcaa ccgccattca agtatttgct cccaacgaac
    12601 cgcaattttt acaatattac aaagcgaatg aggctaagaa attagccaat cctatttggt
    12661 gcctaggtgc aaaggacatt ctaaagagga ttgtggcatc aggctcgcgt aattttttaa
    12721 tatcccatcg tgatcatcag gtcaatgatt tgctggagca ggctgggctt ttgggctatt
    12781 ttaccgaggt tgttaccgcc tcaaatggct ttgccagaaa gcctaaccct gagagcttac
    12841 tttatttgaa ggataagtac ctgatcagcc agggcttagt gattggtgat cgcagacttg
    12901 atatagaagc aggacaagca gcaggctttg atactctgct tgttgatggt agaaaaaacc
    12961 tattggagat agtagattag atggttgaag aaaataaaca attagaagac aaggctcaag
    13021 agtatgacgc tagccagatt caggtcttag aggggctaga ggctgttcgt atgcgtcctg
    13081 gaatgtatat cggctcaact gccaaggagg gcttacatca cctagtttgg gagattgttg
    13141 ataattctat cgatgaagcc ttggcaggct ttgccagtta tattcaggtt tttattgagg
    13201 cagacaattc gattaccgtt attgatgatg gacgtggtat cccagtcgat attcaagcta
    13261 agacaggccg gcctgctgta gagacagttt ttacagtttt gcatgccggt ggaaaatttg
    13321 gcggtggcgg ctataaggtt tccggaggac ttcatggtgt tggctcctca gttgttaatg
    13381 ccttatccac acagcttgat gttcgtgtct ataaaaatgg gcatatccac tatcaggagt
    13441 ttaggcgtgg tgctgtagta gatgatctag ccatcattgg aacgactgat gttacaggaa
    13501 caacagtgca ttttacacct gatccagaga tctttacaga aacaacagaa tttgattatc
    13561 aagtcctggc aaagcgtatt caagagctag cctttcttaa tcgtggctta aaaatctcaa
    13621 ttacagataa acgagctggt cttgaaagag aagagcattt ccattacgag ggtggtattg
    13681 gctcttatgt tgccttttta aatgacaaaa aggacgtcat cttcgatact ccgatttatt
    13741 ctgatggtga gctggagggg ataacagttg aggtggcgat gcagtacact acaggttacc
    13801 atgagactgt tatgagcttt gccaacaata ttcacacaca tgagggtggt acccatgagc
    13861 agggctttag aacagctctg acgcgcgtga ttaatgacta tgctaagaag gctaagattc
    13921 tcaaggaaaa cgaagacaat ctgacaggtg aggacgtccg cgagggcttg accgctgtta
    13981 tttctgtcaa gcacccaaat ccacagtttg aagggcaaac aaagacaaag ctaggaaatt
    14041 ctgaggttgt taagattacc aatcgcctct ttagcgaagc ccttcagcgc tttctattag
    14101 agaatccgca ggttgcccgt aagattgttg aaaaagggat tctagcctct aaggctcgca
    14161 ttgctgccaa gagagcgcgt gaagtaaccc gcaaaaaatc aggcctagag atttccaatt
    14221 taccaggaaa gctggctgat tgctcctcaa atgatgctag tcaaaatgag cttttcatcg
    14281 tggaggggga ttcggctggt ggatcagcga agtcaggccg caatcgtgag tttcaggcta
    14341 ttctgcccat tcgtggtaaa attttaaacg ttgaaaaagc aacaatggat aaaatccttg
    14401 ctaacgaaga aatcagaagc ctctttactg ctatggggac aggttttgga gcggagtttg
    14461 atgtttctag agctcgctat caaaagctgg tcattatgac tgatgcagat gtcgatggag
    14521 ctcatatcag gacgcttttg ttaacgttga tttatcgctt catgcgacca gtattagagg
    14581 ctggctatgt ttacattgct cagccaccga tttatggtgt taaggttggc agcgagatta
    14641 aggaatacat tcaaccggga gtcaaccaag aagaggagct aaaggctgct cttgaaagac
    14701 atagcacagg acgctcaagg ccgactattc aacgctataa gggcctagga gagatggacg
    14761 atcaccagct ttgggaaaca acaatggacc ctgataatcg tctaatggca cgtgtgaccg
    14821 tagatgatgc ggcagaggct gatcggattt ttgacatgct gatgggcgat cgtgttgagc
    14881 caaggcgtga atttattgag gaaaatgcgg tctatagtac gcttgacatt tagtcaaata
    14941 tattttgaaa agcacctaaa agtatgttat aatcgtaacg ttatagtgta tttttgataa
    15001 tataataaaa ggcgattctt gctagttgtt cctactgaac cggcagttga tcaatcgcat
    15061 ctaaataata aggagattaa gatgtcaagc ggaattatct tgctgattgt ggccatagtc
    15121 ttactagtga ttattgctta tttagtgggt gttattatac gcaagcgtaa tgacacatta
    15181 attaccagtc tagaagaacg aaaacaagct ttatttggcc ttcctgttaa tgacgaaatc
    15241 gaggaagtca agtctcttca cttgattggt caaagccaga cctcatttcg tgaatggaat
    15301 caaaagtggg ttgatttgac cctaaatacc tttaccgata ttgaaaagca tatctttgag
    15361 gctgagcact taaatgacac ctttaatttc attcgtgcca agcatgagat taatagcgtt
    15421 gagagtcaat tgaatctcgt tgaagaggat attaccgcta ttcgtgaagc acttggcata
    15481 ttaaaggagc aggaagaaaa aaacagcgcg cgtgttactc atgcactaga tttgtacgaa
    15541 aagttgcagg cttccgttgc tgaaaatgaa gataatttcg gatcaacaat ggccgaaatt
    15601 gaaaagcaaa tgaagaatat tgaagcagag ttttcacaat ttgttgccct taattcatca
    15661 ggtgaccctg ttgaagcagc ggaggttttg gataaggctg aggagcacac gattgccttg
    15721 gggcaaatta cagagcagat ccctgctatt gtagcaaagc ttgaagatga ttttccggat
    15781 caattggacg atctggagac aggctatcgt cgtttgctgg aggaaaatta tcacttccca
    15841 gaaaaaaata ttgaagcccg ctttcaagag attcgtgagt ctattcgtgc caattcatca
    15901 gagctggtta cccttgattt ggaccgagct agagatgaaa atactcacat tcaagagcgt
    15961 atcgactcac tgtatgagct ctttgagcgt gagattgcag cctacaaggt ggttgctaaa
    16021 aatagcaaaa tattaccaag atacctggct cacgccaagc acaacaacga gcagttgaag
    16081 catgagattg ctcgtctatc acgtaagtat atcttgagtg aaaatgaagg cttaaatatc
    16141 aaggcctttg acaaagacct caaagatatc gaagacaatg tccttgagat tgctgaagcc
    16201 tttgatcagc aggaaaagcc attttcagag ctacagctga ttcttgatcg tagtatcaag
    16261 acgttggctt ctgtagagtc tggtcagatg gacgtctttg ctgctgttaa agacattgaa
    16321 aagattgagt cacaggctcg ccagcactta gaaatctacg tcacacagct tcacatgatt
    16381 aagcgttata tggaaaagcg caatttaccg ggaattccgc aggattttct gagtaccttc
    16441 tttaccacta gttcgcagct agaagcattg atggacgagc taagcagagg acgcatcaac
    16501 attgaagcgg tgtcccgtct gtctgaggtg gcaacagctg ctattgctaa tctagaagag
    16561 ctaacctacc aagtggttca gcatgctacc ttgacagagc agctgctcca gtactctaac
    16621 cgttatcgtt cctttgaagc tggcgtgcaa aatagctttg agcatgcttt gaaattgttc
    16681 gaggtggaca atgactatca ggcatcgttt gatgagattt cttatgcctt ggagacagtc
    16741 gagccaggag tgacagagcg ttttgtcaat tcctatgaga ggacacgtga acgtatccgc
    16801 ttctaatgtg acaagggctg atactttata ttacgaaaaa gcttgaaaaa gcagtccatg
    16861 ctgggctatg ctttttcaag ctttttgaat ggtcaggcta tggcctcctt gagctatacc
    16921 caaaaagctg gttcaagcca gtcagtagag atagacaagg ccttagtgct attgggctgt
    16981 tgctacatga gatattttgt aagaaaatca gacgattatc catttaatta aaaaaaaaaa
    17041 aacgaaactg cggaggaaac ctgacgagta actatttatg gctatcaatc agcatgttac
    17101 actctttttg gaaggcctag cagtcactga ctgtgaggtt aaccaaagaa aataagatgt
    17161 taaggagaat atcaatgaaa gtaactaaag cattgtgcgc cttggctgct gcagccaccc
    17221 tagccttggc accaatcagc tcaagtcctg caccaacaca gactgtattt gctgctacac
    17281 gtggtactga agagtactgt cataatgggt ggtgcagttt tcttgatgaa catggtgagt
    17341 ggaacacgaa acgtgagggc gaatctaata gtcccctaca gcgaggttca tggtgggatt
    17401 ggatttctta ttggtctggt tatatatggt attctgtata taactggttt aggtaacctc
    17461 tcaacgccac tgctgccata ctgataaatc ccttagacta ttctaaggga tttttactgc
    17521 aaaaagcaca tagggacaag gcaatacaag ctccagcctg ttcttagttc cttatacagg
    17581 taaggatcat gacaccagag ctcccgaaga cgatcatagg agctattgga gagtgagact
    17641 agtgaaagag cctctgccag agggatttgc ccttagtctt tgtttgttca gcaggcttat
    17701 tgtcagaggg cttgtctagt atagccttga gattggtttc ctctttggtg atggcatgat
    17761 cgctatgaat gattagagca aaaggagaga cagctccttt ctcatctaca atagtggcag
    17821 atagagcgtt ttgttgggcc aatttcatat agtacatttg ataagcagag ccgaattcag
    17881 aggataattt gaatgacaag gggaaataag cctctttgag gtgaggcagc tgggctgtga
    17941 tgtagccttt agccttttca tgatcaacct ctgtcaaggg aagcgctaag acaatccttt
    18001 cagcataggt ccctaaataa tagcgttgtt ggtcggggtc aaatcggttt tctcctgaag
    18061 ctccctttaa gagtcttgta tctaatgagt ccataccagt cctttcaagc atatgatact
    18121 gtcattatac tattaactgc gccaaatacc aatgataaag catttgatcg gcttttggaa
    18181 gaagatgaaa tcaaagaaaa acagcatgaa aacaactctc ttatttcatg aaattagttt
    18241 ttaagttgct taagacccta gtttgtggta ttattaacat gtaaaatatt aaaactcata
    18301 aggagagtat tataatgtca attattactg atgtttacgc tcgcgaagtc cttgactcac
    18361 gcggtaaccc aacacttgaa gtggaagttt atactgaatc aggtgctttc ggacgtggta
    18421 tggttccttc aggagcttct actggtgagc atgaagcagt agaacttcgt gatggcgaca
    18481 aatctcgtta ccttggtctt ggtactcaaa aggcagttga caacgttaac aacattatcg
    18541 ctgaagcgat cattggttat gatgttcgcg atcaacaagc tattgacaga gccatgatcg
    18601 ctcttgacgg tactccaaac aaaggtaagc ttggtgctaa tgctattctt ggtgtgtcta
    18661 tcgctgtagc gcgtgctgct gctgactacc ttgaggtgcc actttacact taccttggag
    18721 gattcaatac taaggttctt ccaactccta tgatgaatat tatcaacggt ggttctcact
    18781 cagacgctcc aattgctttc caagagttca tgattatgcc agttggtgca cctaccttca
    18841 aagaaggtct tcgttggggt gctgaggtat tccatgctct taagaaaatc cttaaagcgc
    18901 gtggacttgt tactgctgtt ggtgacgaag gtggatttgc tcctaaattt gaaggaactg
    18961 aagatggtgt agaaacaatc cttaaggcta tcgaagctgc tggctatgaa gctggtgaaa
    19021 atggtatcat gattggtttt gactgtgcat catcagaatt ctacgataaa gagcgcaaag
    19081 tctacgacta cactaagttt gaaggtgaag gcgctgctgt tcgtacatct gcagagcaaa
    19141 ttgactacct tgaagaattg gttaacaaat acccaattat cacaatcgaa gacggtatgg
    19201 acgaaaatga ctgggaaggc tggaaagcac ttactgagcg cctaggcaaa cgtgttcaat
    19261 tggttggtga tgacttcttc gttacaaaca ctgaatacct tgctcgtggt atcaaagaag
    19321 gtgcagctaa ttcaatcctt atcaaggtta accaaatcgg tactttgact gaaacctttg
    19381 aagctatcga aatggctaag gaagctggct acactgctgt tgtatcacac cgctcaggtg
    19441 aaactgaaga ttcaacaatt gctgacatcg cagtggcaac aaacgctggc caaatcaaaa
    19501 caggttcatt gtcacgtact gaccgtatcg ctaaatacaa ccaattgctt cgcatcgaag
    19561 atcaacttgg tgaagttgca caatacaaag ggatcaaatc attctacaac cttaaaaaat
    19621 aatttgattt taaattaaaa ggttgacaag ctttgatttt aaagcattct aggactgtcc
    19681 tagaatgctt ttagttttgg cttcatgtca actgtagtgg gtgactgata gctaagcacg
    19741 agaggagacg aaggtcgcct tctctttttc aatcggataa ggctagggaa tccccaaatg
    19801 tcgatgaagg aaattttaga gggcttctag aagttgtact taatctgagt ttccttacag
    19861 cgcttacatt taggaggctg atggtcaagt gtagcaatga cttcgatatg agtatcatgc
    19921 tgaatggttt tatccaaggt gatatttttg tctttaattc caatgagtaa tgtagtattg
    19981 ttgatctgtt ccataagata ctttctaatg agttgtttga tcgcttttca tgataagcct
    20041 tatgggactt tttttgtatt caaaaagctc tataatttcc atggtgaatt tacccactac
    20101 agaaattata gagccaatat ttagaggatt ttagcctgtt ggcagattga cagcttctta
    20161 aagatgtgtt acaatgtaac acaaagaaac gaggtaaaca actatgggta cagttactat
    20221 cagattaaat caagaggaag aaatattttt caaaagttac gcccaactca cagggcaaag
    20281 tttatcaagt ctatttaaaa aagcccttga gcgggatatt gaagatgagt atgatttaaa
    20341 actctatcat caagcctatg ctgaatataa agcagaccct gagacaatta gccatgcgga
    20401 ttttaagaaa gagctaggct tataatatgt atcatataga gtattctaaa aaggctcaaa
    20461 agcagattaa gaaactagat aagcaaattc agaggttgct atttgcttgg attgataagc
    20521 atttagaggg aacagataac ccacgcgcaa atggtaaggg tgtggcagga aatcatgcta
    20581 atgaatggcg ttatcgtatt ggtgattatc ggcttatttg tgatattcaa gatgataaga
    20641 tggttatttt agcgcttgag tttgggcata ggcgagatgt ttattaaaca tataaaaaat
    20701 agcacccgtt aaggtgctat tttcttgcct gaactcatca attcaatacc ttttttactc
    20761 ctcctctagt atattatact ttacgtttta gagagaaaaa ggtaaaaagt gggttagtaa
    20821 ttaagcgtat tttattgaac tgtttgctat tgggataacc ttaaaaataa tctctttatg
    20881 gggttagggg cgtaaaagtc ctgatatcaa gaccttggga catcttccaa atgtgacccc
    20941 ttttatcaat tattgatggc tgtttcatca tttgagacag cttttttggc attttcttga
    21001 ttagtatgcc aataaacatt ttcagtcatc atcaagctag agtgtcctag tctgtactaa
    21061 agatctttag ggctagcttg atcgtagagc atcgtataga aatgtcaaca tgagcaagca
    21121 aacatgcgat tatagagatt tttaaccaga tagcttaaga gctagtagaa gctatcaaat
    21181 caatgaataa ctcatgaaag tgcatgataa gataatatat ctagaaaagg aagatgatga
    21241 gcacagtagc tattagattg tagcaaagat tgatttgcgg tatttaagat gataagatgg
    21301 tggtgctggc acttgtgttt ggatataaaa aagatttaca aaaagtaaac agcatagacc
    21361 atcactaggc atatcttttg tttactgaac ttatcatttt agttcctttt tgtgtctata
    21421 gtgtcataag cttataccag tttttggaat atgacagtaa aacggtttta tgatataggt
    21481 ctattctgta ttgttagatt tatagcaggt tatttgaaca gatcatctgt ttagcccttt
    21541 tgaaaaggca gaggtgttca atagtcgaag gacttagcag ctgctctctg ctatacaggt
    21601 aggagagggc tggtgcgggt ggctggtatt gatcaggctg atgataagac taaatggcta
    21661 atcttgtcag caattagcgg gagtagctgc tgtagttgaa ggaaatagca aggctttgaa
    21721 ggcttgatag tatcaggtat tcacgacgaa aggtaggaat aaggagggtg atgatggcta
    21781 aatggttatt ttttgatgtg ggctcaacct tgattgatga atcccttgct tttaatgcgt
    21841 ttatgaagca gtggcgtatc agtctagctc gttgtggaaa gcaattaact agagaagaat
    21901 tactatcctc aatcaatatg ctgacagccg cagggatttg tgagtttgat ttgctttggc
    21961 agcgtcttgc ttctaagggt tgtcagcgtc ccaaatggag tcatcagctg gagaggctct
    22021 ttgcagatac gaagccttgt ctacaggtct tgtctaagac ttatcagctg ggaattattg
    22081 ctaatcaggc aaagggtcta aaagagcgct tagagaggtt tgggattagt cattattttg
    22141 ctcttattgt atcatcttct gatgtggggc tacaaaagcc tgatcttgct ctgtttcgct
    22201 atgcacttga tcaagcaggc gtattagcgc gtgatgctgt ttatattggt gatcgtgttg
    22261 acaatgatat tattcctgct aagacactgg gaatgacagc tatcaggatt catcaaggac
    22321 ttgctgcgtc cagtccggac gataggcttt atcctagtga tgtccatatt agcaagctta
    22381 gtgacctgtt aaaatgcttt taaccagtct ttagcttgaa ctagcttttc tttgtggtct
    22441 ttctgggtga atggcagcaa gctttggagt catgttatgg ctagaccttg gatctaaggg
    22501 tgctgagcgt ctcatatgat gaggccgatc aagtagcctc cttgacaagt agattattgt
    22561 ttggtagctg ctatttttga ttataggtga ctttaggtga tgactggttt tgcttcaact
    22621 aaggctcgct attgctatct ggggtatctt ctgacttttt taatgtgctc ttatctggtt
    22681 ggattagacc tgctccttgc ttgaggaaag ctgtttttaa cgcttatgaa tctaggaaat
    22741 ggtgtgattg gtgttggctt tcactagttt tttgtgttta cttgggctag ctttatatga
    22801 gaaaaaaaga aaaatattta ttttatctgt tatttttgtt acaataagcg tgtaaactaa
    22861 gatgcattaa aaaggagttt ttatgtcgaa taagaaattt tttacttatg cttcattatt
    22921 ggcattaatc gctgttccta ctgtggttga agaggtgact gcacagcctt cagctcagct
    22981 tgtttacgca gatgagctaa ggctatcacc aagtaccgac tcatctccag taacaaagac
    23041 cgatgaggct gatcagccag ctgctcaatc tgtttctgcg acagaaccag tagaggctct
    23101 tgttattgcg gataaagaaa gcgctttaaa tcctgctgtt ctagctgatg ccgatggaag
    23161 tcagccgatt gcagtggtta gagctggtca agagggtcag ccttataccg ttactggcaa
    23221 aatcatcagt gctgtgaatg gttggggtgg taatggcttt tatatccaag acagtcaggg
    23281 gacaggtctt tacatttacc caggaagctc tttggggtat gcgactggtg atgtggttca
    23341 gttgacagga acactcacta actacaaggg tgagctccag cttaaagatg tcacagacca
    23401 taaaaaggta gaaggagacc taccgacgcc tgttgctgag gtaaccattc cagacttaaa
    23461 acaggcacac ccgtccactt tggtaaggct atcaaatgtg actgttggag atatttcatc
    23521 agataagcac gaaacctcct cttttaaggt taccgataca gctggcaata gtgttgcggt
    23581 gcgtcttgat aatcgtacag gtgttaagac ctctgattta ctgtctaaaa tcggtaaggg
    23641 tgatgtgatt aatctgacag ctattcattc tacctttgat ggcaagctgc aattgaagcc
    23701 ttttaatctt gaccaatttg aggtggtcaa aaaggctgtt agagaagagg agattacccc
    23761 tcgtggtcag gtggttaaga ttggccaaat tcaaggtgcc agccacacct caccgctctt
    23821 gaatcaggct gtaacagtaa aagaggtggt tgtgacctat cttgatgatg caactcattt
    23881 ctacgtgcaa gatattaatg gtgacaacga taaggcgacc tcagacggta ttcgtgtctt
    23941 tgctcaaaat gctcaggtgc aggctggcga tgtgctgact atttctggaa cagtggagga
    24001 gttctttggc aagggctatg atgaccgtaa gcagacggat ctgaccatta cgcaaatcaa
    24061 ggcatctaag gtcactaaaa cagggactgc tcaggtacca gctccgcttg tgctaggtaa
    24121 ggatcgtgtt gctccagcca atatcattga taatgatggc tttagtgttt ttgatccaga
    24181 agaggacgct atcgattttt gggaatcctt agagggaatg cttgttgcag ttgacaatgc
    24241 caagatttta ggtccaatgt ctcataaaga aatctatgtt ttgccaggct catcaacccg
    24301 catgctgacc aattcaggcg gtatcctgct gcctgaaaca ggctataata cagacctgat
    24361 tcctgttctc tttaaatatg gaaagcaaac cattaaggct ggtgactcct ataaaggacg
    24421 acttacaggt cccgtgtctt acagctatgg taactataag gtctttgtcg atgacagtag
    24481 tcatatgcca gttttgactg atggccagct caagcctgaa aagacacaga tcaaaaagga
    24541 ccctagcaag ctaagcattg cttcttacaa tattgaaaac ttctcagcaa atccatcatc
    24601 aaccaaggac gaaaaagtaa agcgcattgc agaatccttt attcatgatt tgaatgctcc
    24661 tgatattatt ggtcttattg aggttcaaga taataatgga cctactgatg atggcacaac
    24721 cgatgcaaga caaagtgctc aacgattgat tgatgcgatt aaagcattag gtgggccaac
    24781 ttatcaatat gtggatattg ctccagaaaa taatgctgat ggtgggcagc cgggcagtaa
    24841 tattcgcaca ggcttcttgt atcagccaga gcgtgtcagt ctttctgaca agcctagagg
    24901 tggtgtcaat gacgctgtga agtgggtaaa tggcgagcta agcctcagcg ttggacgaat
    24961 tgatccaacc aatcctgctt ggaagagtgt tagaaaatca ctggctgctg agtttatttt
    25021 ccaaggtcat aaggtggtag tggttgctaa tcatttgaat tccaaacgag gagacaattc
    25081 attatatgga cgtgttcagc cggtaacctt taaatcagag gaaagacgtc atgtcttagc
    25141 aaggcttttg agccaattta ctaaggaggg tgctagtcag caggctaata tcgttatgct
    25201 gggtgacttt aatgattatg agtttacgaa gaccattaag ctgattgaag aaggagatat
    25261 ggctaatttg gtaagcaggc atgaccgctc tgatcgctat tcttacttct atagaggaaa
    25321 tgaccaaacg cttgataaca tgctggtttc acgcaatctg cttggccgct atgaatttga
    25381 tatggttcat gtgaattcac catttatgga agcgcatggt cgtgcttctg accacgatcc
    25441 attgcttctt cagctgtcct ttggaaagga caagccagca gcgccatcac atcagccagg
    25501 gacaagacca gcaccagctg cgaccgctaa accagctaag gcagcgcgtg cacagctgtt
    25561 gccaaaaaca ggggataagg ctggccttgt gatcagcatt ctaggcttaa cagctgtctt
    25621 tagctccttt agcctgttta ggaaacgtca ggaaaggaag taaaggattt cttcggctat
    25681 atcatgaccg gtttagtggc tgagctaaag cttggttaag tcactatggc tagctcttga
    25741 tactagcagt tgctaaggca aggctggctc taagagggtc aagtgataga cctattgcta
    25801 aatagcaata ccaatacaat acttatacca aaaaacgaac gcgtaggctc tttatgatgg
    25861 tagggcgtct gcgttcgttt ttcttttggc tcttggttag ctagattagg cttgtcttta
    25921 ggctgactgc ttagcttatt ttggatcagg atagtaaggc tctagcttgg gcttaagagc
    25981 agtggtgcga ttgtcaaggc ttatttcttt cggagaggct aaaggacgat gagactgtgt
    26041 ttcttgtcat ctgatgtggc ctgcttgttt caaaggcttt aggctgcttg ctgttttttg
    26101 tgacaaacgc atgaaaaatc catgctatgg ggtttcaagc ttaaaagatc atgcttaggc
    26161 acacctagta ttgtagccat aatgcttcta aaacatgttt ttaactgtga tgcgtttatc
    26221 ttgagctatt taaaaaatgt aatctcttat ttttgcaagg atcttcagta gctggctgtg
    26281 cctggctttt agtggctgct tttcttttta tgactggatt tgctgctctt tttgtcaata
    26341 gcttagtttt atggtacaat gtaggcgttg cttagcaacc cttggtgctt agttcccttt
    26401 caccaagcat attacaaacg tggtagagct gtgtatagct ctagtctgac gtcaaaggag
    26461 aaacacatga caagttttac tgttcgtgac tatgttcaca ttgctctagt ggctgccctt
    26521 tatgtggttt tgacaatcac tccacctttg aatgctattt cctatggcat gtatcaattt
    26581 cgggttgccg agatgatgaa ttttttggct ttttaccata aaaagtatat cattgcggtg
    26641 accttgggct gtatgattgc taatttttat agctttggct tgattgatgt tttggtgggt
    26701 ggaggctcaa cgctcatttt tgttagctta ggtgtcgctt tatttaagca ataccaagag
    26761 gaatatctct taaatggctt gctgaataag gcctttgttt atttctcact attttttgcg
    26821 acttctatga tcaccgttgc gattgagctt tacttctttg gagcaccatt tttcctaact
    26881 tggtttacca ctgctgtagg ggaatttgct tcacttatca ttggctctat gatcattgat
    26941 cgcttatcaa aacgcattaa tttacgacaa taatagtaac atgtagcctt ccgtttttgg
    27001 gaggcttttt atgattttct tctagctagg caatagctta tttgctatgt tttgtgataa
    27061 aataagacta tgaaaaaacg aataagagaa ttgactgatc tgttaaatca ataccgtcag
    27121 gagtattaca ccaatgacgc tccttctgta tctgatagtg agtatgataa gctttatcgt
    27181 gagcttgtag agctggagca gacctatcca gcctatatcc taaaggacag ccccacacag
    27241 ctggtgggcg gtacgatttt gacaggattt cagaaatatc agcaccagta tccgctcttt
    27301 agtttgcagg atgctttttc acgtgaagag cttaacgcct ttgatcagcg gatcaaatca
    27361 gcctttcctg aggctgaata ccttgctgag ctaaaaattg atggcttatc catttcattg
    27421 gtttatgagg ctggtatttt aaaagttgga gcgacgcgtg gcgatgggac tattggcgag
    27481 aatatcactg aaaacattaa gaatattaag gatattccca aacggctaag tcaagcactt
    27541 gatgtgacga tacgaggaga ggcctatatg tcgcgcaagg cctttaagac gatcaatgaa
    27601 gagcgtcagg aaaatggtga gccagaattt gccaatccaa gaaatgcagc ggcaggaacg
    27661 ttgcggcagc tggatactag gattgttgcc aagcgacagc tagcgacctt tttgtatcag
    27721 gaggtaggct tagaggctgc tgatagccag caaaggacct tggagcgctt ggctgattta
    27781 ggcttttcgg tcaatagcca ctatctgctg tcctcatcga tgaatgacat ttgggacttt
    27841 atccagagca ttgaagccac tagagaagag ctaccttatg agattgatgg tgtggtggtc
    27901 aaggttaatc agttggcgat tcaagaggag cttggcttta ccgtcaaggc accacgctgg
    27961 gctattgctt ataagtttcc agcagaagaa aaggaagctg agattgtatc tgtggattgg
    28021 acggttggcc gaacaggtgt ggtcacacca acagctaatt tgacccctgt gcagctggca
    28081 ggcaccactg tcagtcgagc gaccttgcat aatgttgatt atatcgcaga aaaggatatt
    28141 cgcattgggg atacggtggt ggtgtataag gctggagata ttattccggc tgttttacga
    28201 gtggttgagg caaagcgcag caatcagact ccaatgccta ttcctacagc ctgtccttct
    28261 tgtcagagtc agctagtgca ttttgaggac gaggtagctc tgcgctgtat taatcctttg
    28321 tgcccaagcc ttattcagcg gagcttggag cattttgcca gtcgtcaggc gatggctatt
    28381 gctggacttg gtccggcagt tgttgaaaag ctttactctg ctggcttggt gcatgatgtg
    28441 gcggatattt accggctaag cttggaggac ttgctgacgc tagatggcat caaggaaaaa
    28501 tcagctgaaa agctcttggc agctattgaa caatcaaagg ctaactcagc tgaaaagctc
    28561 ttgtttgggc ttggtattcg tcacgttgga gcaaaagcca gtcgcttgat attagaaacc
    28621 tatggtgatt tggagacctt gttaagcgtg actgctgagg agctagcgca aattgacgga
    28681 cttggtcttg tcatcgggca atcgctggtg cagtatttcc agcaggatca agcagctcag
    28741 ctcttagctg aattaaagtc ggcaggtgtt aatctagctt atttgggcca aagacctgat
    28801 cggcaggctg agctttttgg actcacagta gtattgacag gaaaattaga aaagctaaac
    28861 cgtacccaag ccaaggaaaa gcttgagcag cttggtgcca aggtaacagg aagcgtttct
    28921 aaaaaaacag atttagtggt tgctggcagc gaggcaggct ctaagctggc aaaggctcag
    28981 caattgggca tcagaattga aaatgaggat tggttgctca atctttagtg aggtaataac
    29041 atgaaaaaac aaatgagggc tcgtctgatt tacaatccaa cctctggtca agaaatcatg
    29101 aaaaaaaacg ttgcagaggt gctggatatt ttggaaggct ttggctatga aacctctgcc
    29161 tttcaaacga cagcagctaa acactcagcc ttaaaggaag caagaagggc ggcaaaggca
    29221 ggctttgacc ttttaattgc tgctggtgga gatgggacga tcaatgaggt ggtcaatggc
    29281 attgctcccc tagagaaaag acctaagatg gcgattattc cagcaggaac caccaatgat
    29341 tttgctaggg ccttaaaggt accaagaggc aatcccgttg aggccgctaa gctgattggt
    29401 aaaaatcaaa ccatccgcat ggatatagga cgtgccaaaa aagacactta ttttatcaac
    29461 attgcagccg caggaagcct gacagagctg acctatagtg tccctagtca gctcaaaacc
    29521 atgtttggtt acctggctta tctggctaag ggggtggagc tcttgcctcg agtgagcaat
    29581 gttccggtga aaatcacaca tgatcatggc gtctttgaag gagaggtatc aatgattttt
    29641 gcagccatta ccaactctgt gggtggcttt gaaaagattg cacctgatgc taagctcgat
    29701 gatggcatgt ttacccttat tttgattaaa acagctaatt tgtttgaaat tgtgcacctg
    29761 ctgcggctca ttattgatgg cggaaagcat gttacggatc gccgggtgga gtatattaaa
    29821 accagtaaaa tcaccattga gccacaatca gataagcgca tgatgattaa tttagatggt
    29881 gaatatggcg gtgatgcacc aatgacccta gaaaacttaa aaaatcacat cacctttttt
    29941 gccaatactg acttgatttc agatgatgcc cttgtcctag accaggagga gctggaaatc
    30001 gaagagatgg tcaagaaatt tgcgcatgag gtagaggatt tagagcaggg attggaggaa
    30061 tagagctagt gatggataat gcagttattg ttcattatca tagttgcaag ggacactatt
    30121 ttcaattaag tctatggcaa tggcgagatg gtaagctggg caaggacgct tatttttcga
    30181 gatttgatag ctttggagca gttgcttatc tcacttatcc agcaccttat tttttgagcc
    30241 atgcttatgt gattgtaaag gatcagtttt ggcattatca aaccgttgat tttcggattg
    30301 agcgtgatta tggggttcca aagactgagg tatggcttgt tgatggtgat cctacggttt
    30361 attattcgag acaggctgct gtggctagtc gacattatgg tagatgtgat gtgcatgcct
    30421 ttgatatggc tgtcaatagt caggcctttg acaagcgctg gggctttagt ggctggctag
    30481 gctttcgcta tcagcctgag gagacgtctt ttcgtttgtg ggccccaaca gcagaaaagg
    30541 ttgagcttat tttctatgct tcaactgatg agagggctag tgttgccaag gttttgccca
    30601 tgcagcgtgg gcagcagtac tcgccagatc atcatgcaga aaacacctgt ggcgtgtggg
    30661 acattagcct aagaggtgat tataattacc atgcttattg ctaccgggtt tattatcgca
    30721 ggcgtacctt tagagacact agggatcctt atgcgattgc gacaacagca aatggtaaaa
    30781 ggtcaatcgt cattgcaccg gagcatttaa agccacaagg cttttcagtg aagcagggta
    30841 aggaggcaac ctggcgctta gacaatccta atcaggctgt gatctatgaa atgcatgtcc
    30901 gtgacttttc aaaatcagaa acctcaggcg ttagcttggc taatcgtggc aaatttaagg
    30961 ggctgattga gacaggcacg cgcaatgcct ttggagattc aacctgcttt gattatgtca
    31021 agtctcttgg cattacgcat attcagctcc agccaatctt tgaccatcat caattctttg
    31081 atgacaatgg tggttatgcc tacaactggg gctatgaccc tgaaaattac aatgttccag
    31141 cagccagctt taccagcaac cctcatgagc ctgcgacccg cattttggaa ttaaaggagg
    31201 tcattcaggc ttatcatgat gcaggcatca atgtgatcat ggatgtggtg tataatcata
    31261 cctactcttc aagagagtca gcctttcagc tgacggttcc ggattattat taccgtatga
    31321 atcctaatgg ctcctttcaa aatggctctg gctgtggcaa tgaaacggct agtgaaaagg
    31381 aaatgtatcg caaatacatg attgattcga ttttgtattg gaccaatgag tttaacattg
    31441 atggctttcg gtttgatctg atgggcctac atgatatcga aaccatgaat cttatcagac
    31501 aggagctaga taagattgac ccaaggatac ttgtttttgg tgagggctgg gacatgggag
    31561 ttggtctggc agctgagcag aaggctaaaa aagaaaatgc cagccaaatg cctggaatcg
    31621 gcttttttaa tgatgatcag cgtaatgcag ttaaaggggc agaggtctat gggagctttg
    31681 agaagggctt tgtatcaggt gcaccgacag aaggacttgt agccaagtct attttgggca
    31741 gtgatgagct ggtttcttat ggtacaccta gtcaggtgat taattatgtt gaagctcatg
    31801 acaactataa cctcaatgat ttgctgtggg tcttgaatcc agaggacagc aagcaggatc
    31861 atgtcaaacg ggttcagcta gcctcagcca tgacgattct catgcaaggg gtttacttta
    31921 tgcagctggg gcaggaattt ttacgaacaa agctttaccc aacaggtcag gataaggagc
    31981 tgacacaggc agaccgagaa agggcgatga attcttacaa tgcacctgac aatgtgaatc
    32041 aggttgactg gagacaggtt agcttggagc gcgaaacgat tgctattatg aaaaaactaa
    32101 tctatctgaa aactaaaaca gctttgtttt catacccatc gtttgagcaa atcagacagc
    32161 atgtttacat tgagcatgct gatgaaaata cgggcttcat tagctttaca gtagaagatg
    32221 aaagaaagta tcgattgatt ttctctaatt ttagaaaccg cttgcaatca cctgctaatc
    32281 atgttataat tgaaacaaat gataagcgct ttcacgatag tgagtccatg ctagatgagc
    32341 tgacagcgat gatccttgac atcacacaat agcctgagtg ttctcaggtt atttttgttt
    32401 gttgtcaagg ataaaaaggc tatagccaca cttagcagag gtctcttagg acctgcttat
    32461 catatcgctt agcgccttga aaaagggttt aggagtaggg aaagaagagg tgatgggatg
    32521 gataatgact tagcgcttta tacctttggc acaggtgaga attttcacat acaggattat
    32581 ctaggtgttc atcgtattaa caatgacaca ggcaccagct atgtctttag ggtatgggcg
    32641 cccaatgcag aggctgtcag cttgattgga gattttactg attggcagtc caatccactt
    32701 gagatgacac gaaatgaggc tggcgtgtgg gaggttacca ctagcttgcc gcaggaagga
    32761 gatatttata agtactgggt taggcgccaa ggtggtcagc ttgttgaaaa aattgatcca
    32821 gtggcctttc tatttgaagc tagaccagga acgggtgcta ttgtcaaaac ccttccggtt
    32881 aaaaaatggc gtgatagctt atggctggga cggcgaaagc gttttggctt taggcagcgt
    32941 ccagttaata tttacgaggt tcatgcccat tcatggaaaa aagacgaaaa cgcaaggcct
    33001 tatgacttta gcaagctaaa agaagagctc attccctatc tcaagagcat gcactacact
    33061 catattgaat ttatgccggt catggctcac cccttagaca tgagctgggg ctatcagctg
    33121 atgggttact ttgcctttga gtcaaccttt ggaagcccag aagcctttca ggattttgtt
    33181 gaggcctgcc atcttaataa tattggtgtc ttgatcgact gggtaccagg gcattttaca
    33241 caaaatgatg acgccttagc ttattttgac ggtacagcta cctatgaata tcaggatcac
    33301 catcgtgctc ataattatgg ctggggggcc ctaaattttg atttgggtaa aactcaggta
    33361 cagtcctttt tgatttcaag tgcccttttt tggctggagg cttatcatgt tgatggtatt
    33421 cgagtagatg ctgttagcaa tatgctttac ttggattatg atcagggtcc ttggactccc
    33481 aatcaatacg gaggcaatca aaaccttgag gggatagcct ttcttcaaaa attaaccaca
    33541 gttatcaagg aaaaacaccc tgatgtgatg atgattgcag aggaggcgac ctcagctacc
    33601 ccaataacca gccctgttgc agaaggggga ctaggctttg attataagtg gaatatgggc
    33661 tggatgaatg atattcttag gttttacgaa gaggatcctt attaccgaaa atacgatttc
    33721 aatctcttga cctttagctt tatgtattgc tttaaggagc attacatttt acccttttct
    33781 cacgatgagg ttgttcatgg caaaaaaagc ctcatgcata aaatgtgggg agaccgctac
    33841 aatcaatttg caggcttaag aaacctttac acttatcaaa tctgccatcc aggtaagaag
    33901 ctgcttttta tgggatctga gtttggacaa tttttagaat ggaaatacga ccatcaattg
    33961 gagtggcaaa atttagagga cgagctcaat gccaaaatgc agcatttcac agccagccta
    34021 aatcagctat ataaggacca tagcatgctg tggcaaaatg atgaaaccta tgacggcatt
    34081 gatattattg atgcagacaa taaggacgaa tcagtcttgt cgttttgtcg tcaaaacaat
    34141 aaaggagagc tcctgctttg tgtctttaac atgacacctg ttgaaagacc aggctttacc
    34201 ataggtgtgc cgatagcagg tctttatcaa gaaattttca atacagagct tgaggccttt
    34261 ggaggtgtct ggaaggagca caatccctta accagcacag tagccaagaa atggaagact
    34321 tatccgcaga ccttgagctt taccctgcct gcactaggag caagcatctg gaaaatcaag
    34381 cgtcgtcaga agcaataagc tattcactgc ttacttagct gtttcaacca aaagaagtca
    34441 ctacagtcat gaaaggataa cgaaatgaag aatggaatgt tagccctcat attagcaggg
    34501 ggacaaggaa ctcgcttagg aaaattgaca cagagcattg caaagcctgc tgtgcaattt
    34561 ggaggtcggt atcgtatcat tgattttgcc ctatccaatt gtgctaactc agggattcat
    34621 aatgtggggg ttatcaccca gtaccagcct ctcgccttaa ataatcatat tggcaatggt
    34681 tcgtcatggg gattagacgg tattaattct ggtgctacga ttttacagcc ctactctgca
    34741 acagagggaa atcgctggtt tcaaggaact agccatgcta tctatcaaaa tattgattat
    34801 attgatagca ttaaccctga atatgtgctg atcctgtctg gtgatcatat ttacaagatg
    34861 gattatgacg acatgcttca gacgcataag gctaatatgg ctagcttgac tgttgctgtg
    34921 attgatgttc ctctaaagga agccagtcga tttggtatta tgaatacaga taccaatgat
    34981 cgcattgtcg aatttgaaga aaagcctgcc aatccaaaat caaccaaggc ttcaatgggt
    35041 atttatatct ttaattggca gcgccttcgg accatgctgg ttgacgcaga aaaaaacaac
    35101 attgatatgt ctgactttgg tcagcatgtg attccgtcct atcttgagtc tggcgagcgt
    35161 gtctacacct ataactttaa aggctactgg aaggacgtcg gaacgattga gtctctttgg
    35221 gaagccaata tggaatatat cggtgaggaa aatgccctag acagtcgtga tcgttcttgg
    35281 aagatttact ctaaaaacca tatcgctcca ccaaacttta tcacagaaga cgctgaggtc
    35341 aaggactctc tggtagtaga tggcagcttt atctctggta aggtcaacca ttctatcttg
    35401 tctaccaatg tgcaggtaag aaagggagct gaggttaagg attcctttat catgagcgat
    35461 gttattattg gcgagggtgc aaggattaca cgagctatta ttggtgaggg agcagtcatt
    35521 ggcgatcatg tggttattga tggcagcaag gacgttcaag tcgtaggcta taatgaagta
    35581 gtgggggtac caaatgaaga ttgataaata ttctgccatt ctaggcagct caattggctt
    35641 tgctgaaatg aaggggctaa cagacacaag accattagcc aacctaccct ttgatgggaa
    35701 ataccggctc attgattttc aattgtccaa tcttgccaat gcaggtgtcc gtagtatcta
    35761 tggtattttt cgtgggcaaa atatccgctc agtgtttgat catatcagat caggtcgtga
    35821 atggggactt aattccttac taagtcatta tttccttggc ttttacaaca caaaagaaga
    35881 ctccaaggag gctgacaagg actattacca tcagatttta acctatctca ggcgttcagg
    35941 gtcagatcag accatttaca tgagctgtga tattctctgc aatattgagc ttgggcaggt
    36001 tattcatctg cataatgcca accatcgcaa cattaccgtt gtctacaaga aaatgccgac
    36061 caaggccatc tctaaggcca acgatatttt agatattgac gagacagata ccgttgttca
    36121 aaggcgaagt ctgtctgagg ggcaggaggt tgaaaaaatg tcagcaggca tttacatcgt
    36181 caatacccca tggttaattg agcagatgga aaaagaagcc gaaaaagaaa accctcaaaa
    36241 gctacgcttc ctcttacgtg atttgattgt gtcagagggc gctcttggtt ttgaatatac
    36301 tggctatctt gccaatatcc actctgttaa atcttatttt gatgctaata tggacatgct
    36361 ggatccgcat aagttttatt cactattata tgctaatcag aaggtctaca cgcgtgtcaa
    36421 aaatgaagag tcaacctatt ttgatgcggc atctgaggtg aacaatgctc aatttgcctc
    36481 aggaagcatt gtcaagggct atgtcgagca ctcaattgtc tctcgcaatt gtcgcattgc
    36541 ctcacaggcg cgtgttgcaa atagtatttt attgccaaag gcagtgattg gtgagggtgc
    36601 tgttgttgag catgctatta ttgataaatc cgtaagagtc gcaccgggtg taaccattag
    36661 aggaagcgct gaggagccaa tagttgttgc caaggggact gaggttgttg aggatatgat
    36721 aaaatgaaga taatgtttgt tgcagcagag ggagctccct ttgctaagac aggtggccta
    36781 ggcgatgtca ttggggcatt gcctaaatca cttgttaaaa atggtcatga ggtgtctgtg
    36841 atactgcctt attatgacgt ggttgatcaa gcctttggtc agcaggttga ggacgtcttg
    36901 tatttttata cgcaggttgg ctggagacgc caatacgtgg gcattaaaaa gcttgtcaag
    36961 gataaggtga ccttttactt tattgacaat caaggttatt tctttagagg caggatctat
    37021 ggtgattggg acgacggtga gcgctttgcc tatttccagc tggctgccat agaagcaatg
    37081 gagaaaatcg gagttattcc agatatttta catgtgcatg attaccatac tgctatgatt
    37141 cctttcctat tgaaggaaaa ataccattgg attcaggcct atcaagcgat tcggacagtt
    37201 tttaccattc ataatattgc atttcaaggg cagtttgatg ctggcatgct aggcgatttg
    37261 tttggtgttg gtatggagcg ctatgaggat ggcaccctgc gttggcatga tggcctgaac
    37321 tggatgaaag cagcagtcct atatgcagat cgggtaacca ctgtttcacc ttcttatgcg
    37381 catgaaattc agacaccagc ctttggaaag ggcttggatc aagtcatgcg aatggaggca
    37441 ggcaagctat caggcattgt gaatggcatt gacactgact tatttaaccc agcaagggat
    37501 cctcatttgc ctgctccgtt ttcagctaag gatctatcag gtaaggcggc tactaaacag
    37561 gccttgcagg aacggttagg gttagcagtc agggcagatg ttccattgat tggtatggtt
    37621 tcgcgcttga cggatcaaaa gggctttcag cttgttcttg aggaattacc gcatatcctg
    37681 cagcaggacg ttcagctggt cttgttagga acaggtgatc ctgattatga ggctgccttt
    37741 tcatggtttg ccaaggccta tccagaaaag ctatctgcta atattacctt tgatctgcca
    37801 ttagctcagc acatttatgg agcctgcgat ctctttttaa tgccaagtgc ttttgagccc
    37861 tgtggacttt cgcaaatgat ggctatgaga tatggcgcga taccgattgt ccatgagatc
    37921 ggcggcttga aggatactgt tgcctcctac aatgcttatg aaaagactgg aactggtttt
    37981 ggctttgatc agttttcagg attttggtta acgcagacgc tcttgtttgc ccttgatatt
    38041 taccataacc acaaggagga ttggcagact attcaacaac atgccatgac caaagatttt
    38101 tcatgggaca cagctagtct ggcctacctt gatttgtata aaagcttact ataacacaga
    38161 aaaggaatgg gaatgcacgt cacaaaagaa caatttattc gagattttaa agatacctta
    38221 catgaggaac aattgattaa ggttcctgct gcaacagctg ctgagctctt cacctcatta
    38281 gcaaagctaa ttcgtaaata ctatacagat acttggattg aaagaaatcg ttccttaacc
    38341 gatcagcagc aaaaaattgc ctattatttt tcgatcgaat ttttaccagg aagaatgcta
    38401 gaaacaaatc ttcttaattt aggcattctt gatacagtta aagaagcctt tgctgacttg
    38461 ggaattgatt ttcaagcagt gaagcatgca gagcacgaca tggctctagg caatggaggt
    38521 ctaggacgtt tggcagctgc ctttatggat tcgctagcga caacaggcta tccaggcttt
    38581 ggaaatgggc tgcgttatcg ttatgggctg tttaagcaac ggattgtgaa tggttatcag
    38641 gtagaattac cagattcttg gtttggctct attggtaatg tctgggagat cagaaaggat
    38701 catgacattg tagacgtcaa gctctttggg aatgtttacc taaaagccaa tcaggacggt
    38761 aagctagcgc caatctatga gggagctcag gttttgagag ctgttcccta cgatgttcct
    38821 cagattggct ttgaaaatga tgtgattaac aatcttcgcc tctgggacgt agaaatccca
    38881 gaagaacatg agcttgatta cccaaccatc gagtcaagac gggcagtcaa ggacattact
    38941 gccattttgt acccagacga cagcagctat gaaggcaaaa agcttagatt gatccaagaa
    39001 tatttcatga ccagcgcagg ccttcaaacc attatcaaat cctatttaaa gcagggcttg
    39061 ccactcactg agcttcatca aaaggtatct gttcatatca atgatactca cccagcagta
    39121 gctccagcag agcttatgag gctcttgatt gacgattatg gcttagaatg ggtagacgcc
    39181 tgggcgacaa ccgtcaaaac catgagctat accaatcata cgattttgtc agaggcctta
    39241 gaaaaatggg acgcagagct ctttaagaca gtgctgcccc gcgtttatca aatcatttta
    39301 gaaattgatc atcgctttgt tgctgaaatg gcgcaaaagg gtattgaccc tcaaaccatt
    39361 gaaaacacta gaatcgttaa ggacaaccag atttatatgg ctcatcttgc cattattggt
    39421 ggctattcgg tcaatggcgt tgccaagcta catacagagt tgttaaagac agataccctt
    39481 aaggactttt atgccttgta tcctgaaaaa ttcaacaaca aaaccaatgg tatcgtgcaa
    39541 agacgctgga cacagattgc tgcgccagag ctatcagcag ctattgaccg caccattggc
    39601 aagggctggc gcaaggatat tcaccagctt cgacaattga gtcaatttac cgaagatcca
    39661 gctgtgctaa atgattttta tcaggtaaaa caagcagcta agcagcgcct agccagatat
    39721 atcttggaaa aaacaggtct tgaggtttca acagaggcta tttttgatgt gcaggtcaaa
    39781 cgcctacatg cctacaagcg gcagctcctg aacgtcctgc atattgtgaa gctttacctt
    39841 gatttgaagg ctaatccgga tttagatatg gtgcctagag tctttatttt cggcgcaaag
    39901 gctgcaccag gctatcattt tgctaagtcc gtgatcaaaa tcatcaatga gctggctaat
    39961 ctcattaacc atgatgctag tctcaaagga aagctaaagg ttgtctttct tgaaaattat
    40021 aacgtgagcc tagcagagct tattatccct gcggcagata tttcagagca gatttcactg
    40081 gcctctaagg aagcttcagg aacatcaaac atgaaattta tgatgactgg tgctatcacc
    40141 ctagcgaccc ttgatggtgc aaacattgaa atcaaagacg aggtcggaga ggaaaacatt
    40201 gtgatctttg gtatggataa ggatcaggtc tatgaccact atgccaagca tgattattat
    40261 tcaagaggct tatatgagag cgaccctcag attaaagcag tagtcgacgc ttttatcaat
    40321 ggcaccattc caaatagtca acacgaaggt atggaaatct atgaggcctt aatcacgcat
    40381 aatgatgaat acttcttgct agaggacttt tcttcctatg taaaagcaca ggctaagatt
    40441 gatcagctct accgtcaaaa ggacaagtgg tcaaaaatgt cgctcatcaa cattgcccat
    40501 tctgacaagt ttacatcaga tgacacgatc acccagtatg ccaaggacat ttggcggctg
    40561 aaacgctaat ccatcaagga agaaaaagca ttagttacct tagattgaag agagtgtctt
    40621 gttggaccgt tttcttcaat ctttttttga tcgcaaaaaa tctgggagtc agatcagctg
    40681 cttgcctaat actttggatt atcaaggtat tttggaattt gttaatcttt ttgttataat
    40741 agtgatgtga agctattttt taaatgaaaa agccaacact tcaagatggt gttaaagtaa
    40801 ggttagtatt agtctaagaa agcgtaacca cattaaagaa acctgttgac attctcaatt
    40861 ttaaggaata gaataacaaa gtaaaaaatt tttaaaagga gtattctatt atgaatccta
    40921 ttttcgcatt ggctcttgcc tgctttggtg tatcacttgc cgaaggcttt ttgatggcta
    40981 atctctttaa atcagcgtca cgccaaccag aaattatcgg tcaattacgt tccttgatga
    41041 tcctaggtgt tgcctttatt gaaggtacct tcttcgttac ccttgttatg gccttcattc
    41101 taaaataaca gcctatttga tatagaaaag gagggtatta aatggaagaa gctaaagtac
    41161 cgatggtaga gcttggtcca ataaccttta atttgaccct acttgctgtt tgtattgtta
    41221 ctatcctact gatatttggc tttgtttttt gggcaagtcg tcagatgaca ttaaaaccaa
    41281 aaggcaagca aactgcgtta gaatatttaa tcagctttgt taatggtatt ggggaagagc
    41341 atttggatag tcatcttcag aagtcttatt cgcttttact ttttaccatt tttctttttg
    41401 tggcagttgc caacaacctg ggcttgttta caaagctaga aacaaccagt ggctacaacc
    41461 tatggacatc gccaacagct aatttggcct ttgacctagc cctatctctg tttgtgacac
    41521 ttcttgttca tatcgaaggc attagacgtc gtggttttgg tgcttattta aaacgctttg
    41581 cgacaccttg gccaatgacc ccgatgaacc tattagaaga atttaccaac ttcctatcgc
    41641 ttgctatcag gctgtttggt aatatctttg caggagaggt tgtgacaggc ttgattgttc
    41701 agctggccaa ttatcgcctg tattggtggc caattgcttt ccttgttaat atagcatgga
    41761 cagccttttc catatttatt tcctgcatac aagcctttgt attcacaaaa ttaacagcaa
    41821 cgtatttagg aaaaaaagtt aatgaatcag aagaataaga agggaggaca aacgaatgtc
    41881 agttacaatt ggtgagctca ttgggaattt tattctggta acaggctctg tcatcgtctt
    41941 gttgctcttg attaaagcct ttgcttgggg tgctatcgaa gctattttac aggcacgctc
    42001 acagcaaatt tcacaggata ttgaccaagc agagcaggcg cgtctcaacg cccagcagct
    42061 tgaaaaggaa ggtcaagcca acttagaagc cagcagatca gaggctagtc agattgttga
    42121 ggcagccaaa gaaactggta aagcacagga gacacgcatt gtagcagagg ctacagaaga
    42181 ggccgatcgc ctaaaagcag cagcgttgac agatatcgaa cacagcaagt cagaggctat
    42241 ttcagccgtt aagacagaaa tgtcagattt gacagtttta ctagcagaaa aaattatggg
    42301 agccaatctt gataaggcgg ctcaaagcca gcttattgat cgctatcttg atgatttagg
    42361 agaggcttaa tgaccaaaaa agaacaagct cttatcgagc aatatgcaaa aagtcttgtg
    42421 caggtctgtc aggagcgaga cactcttgaa gcactgcagg ctgatgtgct tgccatttta
    42481 gaggttttta aagctactaa tcttgctaag acattgtcaa gcttagcggt tccacgtgct
    42541 aaaaggcttg agctagtaag gcagcttcaa ggagataata tcgtttatct gaataacttg
    42601 ctagaagtta tgctgcaaaa tgagcgtgaa gcttatttat atcaagtgct tctaagggtt
    42661 ttatccgagc tggctagtgt ctcaaatcaa tatgacgtga cagttacatc agcagttcct
    42721 ttaagtgagg agcaaaagca gcgtgtgcgt acagtggttt caaagagact tgcagtaaag
    42781 acaggtcgct taatcgaaaa ggtagatcct tctttaattg gaggatttat gattagcgtc
    42841 aataataagg taattgatac aagcattcgt cgtcaattac aagcatttaa aatgaattta
    42901 aaatagaaag tggtgtgact tttggcaatt aatgcacaag aaattagcgc tttaattaaa
    42961 aagcaaattg agaacttcca gccaaatttc gatgtcacag aaactggagt tgttacctat
    43021 attggtgatg ggattgcacg tgctcgtggc ttagacaatg cgatgagtgg cgagcttctt
    43081 gaattttcaa atggtacctt cggtatggct caaaacctag agtcaaacga tgttggtatc
    43141 attattcttg gtgatttttc aacgattcgt gagggtgatg aggtaaaacg caccggtaaa
    43201 attatggaag tgccagtcgg tgaagctctc attggacgtg tggtcaatcc acttggtcag
    43261 cctgttgatg gcttaggtga cattgagaca actggcttta ggcctgttga gactccagct
    43321 cctggtgtta tgcagcgtaa gtctgttttt gagccattac aaaccggtct aaaggctatt
    43381 gatgctttgg ttccgattgg tcgtggccag cgcgagctga ttatcggtga ccgtcagaca
    43441 ggtaagacgt ctgtagccat tgatgccatc ttgaatcaaa aggggcagga catgatttgt
    43501 atctatgtcg ctattggtca aaaggaatca acagttcgga cacaggttga aacgctacgc
    43561 cgttatggtg ctttggatta taccattgtt gtaacggctt ctgcttcaca gccatcaccc
    43621 ttgctgttta ttgcacctta tgctggtgtt gcgatggcag aagagtttat gtacaatggc
    43681 aagcacgttc tgattgttta tgatgacctg tctaagcagg cggtagctta tcgtgaattg
    43741 tcgctcttgc ttcgtcgccc accaggtcgt gaggcctatc caggagatgt tttctacctg
    43801 catagccgct tgcttgagcg ctcagctaag gtgtctgatg acttaggtgg tggctcaatt
    43861 acagccttac catttattga gacgcaggct ggggatatct ctgcctacat tgcgacaaac
    43921 gtgatttcga ttacagatgg tcagattttc ttgcaagagg atctctttaa ctcaggaatc
    43981 cgcccagcta ttgatgctgg ctcgtcagta tctcgtgtcg gtggctctgc acagatcaag
    44041 gctatgaaaa gggttgcagg gactttgcgt cttgacctag cctcttatcg tgagttagaa
    44101 gcctttacac aatttggctc agatctagat gcagcgacgc aagcaaaatt aaatcgtggt
    44161 cgtcgtactg ttgaaattct aaagcagcca ttgcacaagc cattgcctgt tgaaaagcag
    44221 gtggtcattt tgtacgcttt gacgcatgga tttttagatg atgttcctgt agatgatatt
    44281 ttagcctttg aagaagcact ttatgactac tttgatgcgc actatgatca cttatttgag
    44341 ataatccgta caaccaaaga ccttccgcag gaggctgagc tggacgctgc tattcaggcc
    44401 ttcaaagcac agtcaaactt taaataaaag aggggggtac tagtatggca ggctctctaa
    44461 gtgaaattaa ggctaaaatc atttcaaccg aaaaaacaag caaaatcact agcgccatgc
    44521 gtatggtttc ttctgcaaag cttgttaaat ctgagcaagc agctcgtgat tttcaaatct
    44581 atgcttcaaa gattcgtcag attacaacag acttactgaa atcagacctg acaacaggct
    44641 cagataatcc catgctggtg tctcgtcctg tgaaaaagac aggctatatt gttattacct
    44701 ctgataaagg actggtcggt ggttacaatt caaaaatctt aaagtccatt atggacatga
    44761 ttcaggaata ccatgccgct ggcgattatg agattatctc aattggcagc atcggctcag
    44821 atttttttaa ggccagaggt atgaatgttg cctttgagct gcgcggccta gcagatcagc
    44881 caagctttga tcaggtcgga agaattatct cccagtctgt agatatgttt gtcaatgaga
    44941 tttttgatga gctgtacgtc tgctacaatc accatgtcaa tagcttgacg agccaggttc
    45001 gggttcagcg catgctgccg atttctgatt tggttgccga ggaggccgca gaagaaggtg
    45061 tcactggatt tgaattagag ccaaaccgtc atgtgatttt ggagcagctg ctgccgcaat
    45121 ttactgaaag cttaatttat ggtgcgatta ttgatgcaaa aacagcagag catgctgctg
    45181 gcatgactgc aatgcagact gccactgaca atgccaagca tgtgatcaat gatttgacca
    45241 tccagtacaa tcgtgctcgt caagcagcaa ttacacaaga aattacagaa attgtagctg
    45301 gtgctaatgc acttgaataa gcttattgta tgctgatagc gctctagcag agacctatta
    45361 gcacttaatg tcatcttcaa agctagatga catttgggat taatgagcta ggggcctttt
    45421 acccttagct actcgaattt agaaaaattc agcttaatcc cctactatcg aatataagga
    45481 gaaaaacatg agctcaggca aaattgctca ggttgttggt ccagttgtag acgttgtgtt
    45541 tgcgagtggg gacaaactac cagagattaa taatgcgttg atagtttata aagatggcga
    45601 taaaaagcaa aaaatcgttc tcgaggttgc cctagaactt ggagacggta tggtacgtac
    45661 aatcgctatg gaatcaaccg atgggcttac acgtggatta gaggttcttg atactggtcg
    45721 tgccattagt gtaccagttg gtaaagagac tctaggtcgt gttttcaacg ttcttggtga
    45781 aaccatcgac ctagaagcac catttgcaga tgatgttaat cgtgaaccga tccataaaaa
    45841 agcaccagcc tttgatgaat tgtcaacatc atcagaaatt cttgaaacag gtatcaaggt
    45901 tattgacctg cttgcccctt acttaaaggg tggtaaggtc ggtcttttcg gtggtgccgg
    45961 agttggtaaa accgttctta tccaagaatt aatccacaat atcgctcaag agcatggtgg
    46021 gatctcggta tttaccggtg ttggtgagcg tacgcgtgaa ggaaatgacc tttactggga
    46081 aatgaaggaa tcaggcgtta ttgaaaaaac agccatggtt tttggtcaga tgaatgaacc
    46141 accaggagcc cgcatgcgcg ttgccttgac tggcttgaca attgctgaat atttccgcga
    46201 tgttgaaggc caagacgtct tgctctttat tgacaatatc ttccgtttta ctcaggcagg
    46261 ctcagaggta tcagcccttc taggtcgtat gccttcagct gttggttatc agccaacact
    46321 tgccactgaa atgggacaat tacaagagcg tatcacgtca acgaaaaaag gctctgttac
    46381 ctctatccaa gccatctacg tgccagctga tgactacact gacccagcgc cagcaacagc
    46441 atttgctcac ttggattcaa caactaacct tgagcgtaag ctgacacaga tggggattta
    46501 cccggcggtt gatccactgg cttcaagttc acgcgcgctg tcaccagaaa ttgttggtga
    46561 ggagcactat gcagtagcca cagaggttca gcgtgtcttg cagcgctatc gtgaattgca
    46621 ggatatcatt gctatcttag gtatggacga gctgtcagaa gaggaaaaga cattggtagg
    46681 gcgtgcgcgt cggatccagt tcttcttatc gcaaaacttt aatgtcgcag aacagtttac
    46741 aggcctccct ggctcttatg ttccagttgc cgaaaccgtt cgtggcttca aggaaattct
    46801 tgaaggaaag catgaccacc ttccagaaga cgcctttcgt gctgttggac caattgagga
    46861 cgtgatcgaa aaagctaaga aaatgggctt ttagtgaggt gatgccatga cacaaatgac
    46921 tgttcaggtg gttacgccag atggtatcaa atacgatcat catgctaagt tcatctcagt
    46981 aacgacacca gatggtgaga tggggattct gcctaaccac atcaatgtga ttgctcctct
    47041 acaggtgcat gaaatgaaga ttcgtcgtgt cggtgaggac gatcgcgttg attgggttgc
    47101 tatcaatggt gggatcattg agatcaaaga caacgtggtt accattgttg cagattcagc
    47161 cgaacgtgat cgtgatattg atgttagccg ggcagagcgg gcaaaattac gagcagagcg
    47221 tgacattgca gaggctgaaa ccactcatga tattaatgag gtgcaacgcg ctaaggttgc
    47281 gctgcggcgc gctttgaatc gtatcaacgt gagtaaaaag taataacatg agtctagtct
    47341 accaatttga tcaagacaaa gcgattagcg atgcttagga gaaggtgtag ataggctctt
    47401 ttagtttttt cgtcaaaaaa tgtcctcttt tgttagactt ttgatataat aaagctatgg
    47461 aagtaattag aaatctttta atgtttttca gccatttatt atttattggc attagttatc
    47521 agttactcat cagcctagtt gattggtcaa aattcattca ttaccgacca gagaatatgg
    47581 gaaggcttcg cttgcttgtc ctttttttgg caattgcctc aggctatttg gttagtcgct
    47641 ttatgctgga attaattcag attagtcagt atctgctgta tgatttccac tagagtaggc
    47701 agtcaggaag tatgatataa tattagtacg atgaccagta ggaaatggag aagcttgtgg
    47761 ataaaataat catagaaggt gggagcacac gtttagaggg agaggtaacg atcgaaggcg
    47821 ctaaaaatgc cgttcttcct ttactagcag ctactatcct cccctcaact ggaaagactg
    47881 tcttgagaaa tgtgccgatt ctctcagatg tttttacgat gaactatgtt gtgcgtggcc
    47941 taaatattga cgtcgacttt gatgaggctg ccaaccagat tacggttgat gcctcagggg
    48001 acattttaga tgttgccccg tacgagtatg tcagccaaat gcgcgcctca attgtggttt
    48061 taggcccgat tttagctcgt aatgggcatg ccaaggtatc gatgcctgga ggctgtacga
    48121 ttggcagtag gccgatcgat ttgcatttaa agggcctaga ggctatgggc gctgagatca
    48181 ctcagcaggg tggtgacatc actgcaaagg cagatcgcct aaagggggcg atgatctata
    48241 tggacttccc atcagtgggg gctacgcaaa atttgatgat ggcagcgacc cttgctgatg
    48301 gtgtgacagt cattgaaaat gctgcccgag agcctgagat tgttgaccta gcccagctgc
    48361 tcaacaaaat gggggctaag gttcgtggtg caggaactga aaccctgacc ataacgggtg
    48421 tcaccagtct atgtggtgtt gagcatgatg ttgttcagga tcgtatcgaa gcaggtacct
    48481 ttatgattgc tgcagcaatg acctctggta atgtgctgat tagagatgct gtatgggagc
    48541 ataatcggcc cttgatttct aagctcatgg aaatgggagt gtctgttgtc gaagaggacg
    48601 caggcattag ggtgcaggct gatgtgacta aactaaggcc tgtcactgtt aaaacccttc
    48661 ctcacccagg ctttccaaca gatatgcagg ctcagtttac agcccttatg gccattgtta
    48721 agggagaatc tacgatggtg gaaacagtct ttgaaaatcg tttccagcac ttagaagaaa
    48781 tgcgacgcat gggcttacaa tctgaggtat tgcgtgatac agccatgatt catggtggtc
    48841 atgaattgca gggggcgcct gtgatgtcaa cagacctgcg agctagtgca gccctcatct
    48901 taacgggaat ggttgccaaa ggcaagacca ctgtgaataa gttgaaccat ttagatcgtg
    48961 gctattatca gtttcatgaa aagcttgcca agctaggtgc caacattcag cgaattagtg
    49021 aggagtagtc aatgactaat ggttggagat atgtcataaa tcagctaatg ctaatcatag
    49081 ctattggact gctcggactc ttttgtctgg cgctgggact agtgattggc tatagcctta
    49141 tcggtgatgg ccaaaatccc ttagcgattt tatcaccaga taagtgggct gagctgattc
    49201 ataaatttac gggaaagtag gcatggcctg ctttttatga taagaggaaa gatgatcaaa
    49261 aagaagaaag acattaggct gcttaatgcc tttttagcgc tgttgcttgt tcttggaaca
    49321 ggttatttgg caggacatga tgacctagca gctgataacc cgatcaagca ggtctaccaa
    49381 aggattcttg gctctgacac gcagcaagcc gggctaccaa aggcaagccg agactgggac
    49441 actccctcca aggccttggc agattcggtc atgacagcca ccatcaaaca gcaattaggt
    49501 gatgtgatta cttggaatgg cactggtgcc tatatcatta accataataa aacgacgcta
    49561 aatgcaaagg tagccagtct cccctacgcc aataataaaa caaaactggt acaagggcaa
    49621 agtgttccta ccgtagccaa cgccctgcta accaagtcaa ctcgacagta tcagaagcgc
    49681 aatgacactg gaaatggcta tagctcatgg aagcctgctg gctggcatca ggttcaagga
    49741 ttaaagggaa gatacaatca cgcagtagat agaggacacc ttctgggcta tgcacttgtt
    49801 ggcgggctaa agggctttga tgcctcaatg gctaatccca gtaatattgc tactcaaacc
    49861 gcatgggcca atcaagcagc caacgagcga tcaaccggac aaaactatta tgaaacaaag
    49921 attcgcagag ccctagatag caacaagcgt gtccgctatc gtgtaaccct actttatgat
    49981 ggaaataacc tcttagcaag cggcagtcac cttgaggcaa agtcatcaga cggtagctta
    50041 gaatttaacg tctttatccc taatgtacag gctggattgc agattgatta tcaaacaggt
    50101 cagatcactg tagccccttc acagcattag agaggcatat tgcatggtaa aggctgatca
    50161 ctcagccagc catcatggca gagaagcgtt agtccttgta gcccctcaaa gaaaggtgct
    50221 aacaatattt ggtcttgtgg ctttagcaga aaaacagata ggtcctttag ttgaagcacc
    50281 aagcatgtca gctcctggtt aggacaaatg ttaaggctaa gcggtggtaa gctaaaggct
    50341 cacaaaagac aagactagac tggttttttg gctatagtcc tttatgactg atgacagctg
    50401 ataatggatc aagatgattg aggtttctag caatgcttgg gctagcctat cgtcttagtt
    50461 agcgctgatt gatgagatgt tgaacagttc ttgactaaaa gcagccctgc ccttacgcct
    50521 acgtcctggt tagtgaagaa ataagcattg tcataaaggc atttttttgg tacaataaaa
    50581 gtaattgaat agcagtctat gagactagta ctaataggga agttaatagg gaatgagggt
    50641 cgtgactgga agccttctta atgaaacgat taggaattca ctcaatcaat gacgaggtaa
    50701 ttaaggtctg acttgctcag atgaaaacgg atggtaccgc gtgtcaacgc tccgctttag
    50761 ataggagtct tgatacgcct tttttgatga cgtgctgtta ccatcagcta tttaatcaca
    50821 agcaggcact agccagccaa atgcgagtga tcactgtaag catagaaaga taggggctac
    50881 agcttatcta aaaaagcaag ggcgatgatc cctgcctaaa agtctttctt agcttctgtg
    50941 atgtgactag ctgacctagc tgctcacagc tgagcctaag gcctattggc acaaggcctg
    51001 ccagcattaa tgcaatcatt ttccaaacag aagggaatat catggattta caagcacaat
    51061 tagaagaact gaaaaccaag acacaagaag cgctccagca gctaaacggt gatcacagca
    51121 aggaattaca ggagctgcgg gttgctgtcc ttgggaaaaa aggaacgctt accgaactgc
    51181 tcaagggact aaaggatctc tcaaatgatc tgcgtcccgt tgttggcaaa caggtcaatg
    51241 agcttcgtga ctttttgaca caggcctttg aagagcaggc taaggtggtt gaggcagcaa
    51301 agattcaggc caagctagat tctgaaagca ttgatgtgac tttgccgggg cgtcagatga
    51361 agcagggcta tcgacatgtg ctcactcaaa tcagtgaaga aattgaagac attttcttgg
    51421 gcatgggctt tcaaattgtt gatggctttg aggttgaaaa ggattattat aattttgaac
    51481 gcatgaacct tccaaaggat catccggctc gtgatatgca agacaccttc tatatcacag
    51541 aggatatttt gctgcgcacc cacaccagtc ctgtacaggc acgaacactg gaccagcatg
    51601 atttttcaaa ggggcctctc aagatgattt cacctggacg tgttttccgt cgtgacaccg
    51661 atgatgccac tcattctcat caatttcacc aaattgaagg cttagttgtt ggcaagtcta
    51721 tctctatggg agacttgaag gggacccttg agatgatcat taaaaagatg tttggtaagg
    51781 agcgtaagat tcgcctgcgc ccatcctatt tcccttttac tgagccatct gttgaggttg
    51841 atgtctcatg cttcaaatgt ggtggtaaag gctgcaatgt ctgcaaaaaa acaggctgga
    51901 ttgaaattct tggagctggt atggtgcacc caagcgtttt agaaatgtca ggtgtgaatg
    51961 cgcaggagta ttcaggcttt gcctttgggc ttggtcaaga gcgtatcgcc atgctgcgtt
    52021 atggtatcaa cgatattcga ggcttctacc aaggagatag tcgcttttct aagcagttta
    52081 agtaatagtg atcatgtggt caaaaaccaa atcaccagtt tgaaaaaaga actgacgctc
    52141 aatctggagc tgttctttgg gttagaatca gaaaggaaaa agatgggtaa agagcaaaga
    52201 agtgattggt tagcttacct caagcaggtg ctaggcagat ctcttatcag cgctcgctac
    52261 tctattgaag gcttatgtta gtatcttata aatggttgaa aaaattagtt gacattgatg
    52321 tctcaccggc cgagctagct gaaaaaatgt caacaacagg tatcgaagta gaaggcatca
    52381 caagcccctc tgaaggctta tcaaagctag ttgttgggca tgttgtttca tgtgacgcta
    52441 ttccagaaac acacctgcac ctttgtcagg tcaacacagg agatgatgag cttcgtcaaa
    52501 ttgtctgcgg tgcacctaat gtcaaagcag ggattaatgt gattgttgcg ctgcctgggg
    52561 ctcgcattgc agacaattac aagattaaaa agggtaaaat acgcggtatg gagtctcttg
    52621 gcatgatctg ctcacttcag gagcttggct taccagatgc aattattcca aaagattttt
    52681 cagaaggtat ccagatccta ccggaaacag cagcagcagg tgatagcatt ttcccttacc
    52741 ttgatttaga tgacaatatc attgagcttt ccatcacacc taatcgtgct gatgccttat
    52801 caatgcgtgg tgttgcccat gaggtggcag ctatctatgg caagtcagtg tcatttccag
    52861 aaaagcccct tatcgaatca gctaaagcag cagctgatag tctagaggtt gctattgact
    52921 ctgacaaggt gctaacctat gctagtcgta ttgttgaaaa tgttaccgtc aagccaagtc
    52981 cgcaatggct gcaaaatctt ctgatgaacg ctggcattcg tccaatcaac aatgttgttg
    53041 atgtgaccaa ttatgtcttg ctgtattttg gtcagccaat gcatgccttt gattatgata
    53101 cctttgctga tcataagctt ttagcgcgtg atgcgcgtga gggagaaagg cttgtcaccc
    53161 ttgatggaga agagcgtgtg ctgaccacag atgatattgt cattaccgta gcagaccagc
    53221 cagtcgccct ggctggtatt atgggtggta aagcaacaga aatcaccacc tcctcaaaga
    53281 cagtggtgct tgaagcagca gtctttaatg gcaaatcaat ccgcaaaaca agcagtcggc
    53341 taaaccttcg ttcagaaagc tcatcacgct ttgaaaaagg gattaaccat gacacgctta
    53401 tagaggcctt agattttgcg gcagccatgc tagaagagct agccggtggg accgttttag
    53461 cagggcgctt gcaggcaggc tcactgccta ccaatccggt agaggtttca agcagccttg
    53521 attacgtcaa tgtccgcttg ggaacagcct tgagctttac tgatattgag ggtatttttg
    53581 caaggcttgg ctttggtatt agcggaactg ctgaacactt taccgtttca gtgccacgac
    53641 gccggtggga tataacaatt ccggctgacc tagtcgaaga aattgcccgt atctatggct
    53701 atgaccgatt gccaaccaca ttaccagaag ctgctggcac agccgcagaa ttaaccaaaa
    53761 cacaggccct tcgtcgtcag ctgcgtggtc ttgcagaggg actgggttta acagaaatca
    53821 tttcctatgc tctaacaaca cctgaaaagg cccttgaatt tgcaatgaag ccaagccagt
    53881 taacagagct gatgtggcca atgtcagtcg agcgctctgt ccttcgtcaa agcatggtat
    53941 caggtatgct tgacaccctt gcctacaatg tggcacgtca gcagcataac cttgccgttt
    54001 atgagattgg taaggtcttt gagcaagagg gcaatcccaa ggaggcatta ccaacagagc
    54061 ttaatcactt tgcctttgct atcacaggct tagtagcaga caaggatttt cagacaccag
    54121 cccaagcggt tgatttttac catgctaagg ggatcctgga gtgtctcttt gataagctag
    54181 gactgtctgt ggattatatc ccaacaaagg agatggcgag catgcacccg ggacgtaccg
    54241 cacgcattca gctaggagat caagtgattg gctttgttgg tcaggtgcac ccacaggctg
    54301 ctaaggctta tcatatccca gagacctatg ttgcagagct tgacctgact gctatagagg
    54361 cagctctacc agctcatcat gcctttgtgg aaatcaccaa atacccagct atggtaaggg
    54421 atattgcctt attggttgat gcctcaacaa gtcatcaagc tattctttca gcgatcacgt
    54481 ctgccaaggt aaaacgtcta acagagatca agctctttga catttacgca ggagcaacta
    54541 ttgcggccgg taaaaaatca atggcctata gcctgacctt ccaaaatcca acagacaatc
    54601 tgactgatga ggaggttgcc ggctacatgg agaaaatcac caaggccttg gtagaaaagg
    54661 ttggtgcaga ggtgagataa ggacgcttct aatgactagc tacctaaaaa aagctcattt
    54721 caaaggctta gctgcaattg ttctgttgcg gctgagcttt ttttgatgct tagactgccc
    54781 ttatcctatg ctagttgcag caagggttta gagatggttt tatttaaatt atcagtcaaa
    54841 aatatttttt ctaatcaaat tcctagcttt atctgatctc ctctgctata ctgtgcaata
    54901 agtaaggaga ttatatgttt ttagccctaa atgaaataaa acaagctaag ctcagatatg
    54961 gcttgattat gggactgctc tgtttagtag cctatttgat gttcttttta tccggtttag
    55021 cctttggatt aatgcaggaa aatcgctcgg cagttgacag ctggcaggca gatacagttc
    55081 ttttgtcaaa ggacgctgac gccaatctca gcctatcctc tttaaagacc agtcagctta
    55141 aggagatcaa ggctgatgag gtcactcccc tagcccagct gaatacagtt gcttggtcaa
    55201 cccaagctcc aacagaagaa gacaaagaaa aaatcagctt ttttggcatt gagagagagt
    55261 cctttctcaa gcctacaatc acaaaaggaa ggctatttaa gtcagacaaa gaggtggtga
    55321 ttgatcaaag ccttgctgag aaaggaggct ttaagcttgg agatcagctg cgggtatcgg
    55381 cctctaacca gacctatacc atcgttggct ataccaagaa tgctagcttt aacgtgtcac
    55441 ctgttgctta cctcaacctg acagcctttc agggcttact gtatggtcaa gaagcaggcg
    55501 cacaagaccc aaatgttaat gcctttattg tcaagggcaa gctagctgac tatcccaagg
    55561 cagaccttca gcagctagca attaaagact ttattaataa gctgccgggc tacagtgcac
    55621 agctcttgac ctttggcttt atgattgggt ttttagtgtt aatctcagcc attatcattg
    55681 gtatttttat gtatgtgttg accattcaaa aggcgccaat ctttggtatc atgaaggcac
    55741 aaggcattgc taatcgtacc attgcaaatg ctgtgctatc gcaaaccttt gtcctaagcc
    55801 ttttgggcag cagtcttggc ctactaggta cttggctaag ctcgcttgtc ttaccagcaa
    55861 cagttccctt tcagagcaat tggtacctat atgcgcttat cttagctgct atggtaatct
    55921 ttgcagtatt aggcaccctc ttttcagtct ttacgattgt caggattgac cctctagagg
    55981 ctatcggtta ggagaagaac atgacagtat tagcatttaa acaggtcaca aagtccttta
    56041 aggacggtga tcagaccatt gaagccctaa aacagacgga tttttccatt gaagcaggcg
    56101 aatttgtagc cctcataggt ccctcaggct caggcaaatc aacctttctg accattgcag
    56161 gtggtctgca aacaccaagc tcaggacaat ttttagtcaa tggcaaggat tacaccaacc
    56221 tatctgaaaa ggaacgatca aggctacgtt ttaaggatat tggctttatc ctgcaggctt
    56281 ctaatttgat tccattttta accgtcaagc agcagctaga attggttgat aaattgacca
    56341 agaacaagca aaaagcaaag cgtcagcagc tctttgagga cttaggaatt actaaactgg
    56401 ccaataagct gccccaagat ttatccggtg gcgagcgcca gcgcgttgcg atcgccagag
    56461 ccctatacca tgatcctgtg atcattttag cagatgagcc gactgccagc ctggatactg
    56521 aaaaagcctt tgaggtcgtt gagcttctag ctaaggaaag caaggaaaaa aataaggcaa
    56581 tcatcatggt gacacatgat aaccgcatga ttgactattg tgataaggtc tatcgcatgc
    56641 aggacggcca attgagtcaa gacagtcatc atacccaccc tcaaaactaa tcagataaga
    56701 aagatcctgc tgtaagcgat atagcaggat tttttagctg ctctaagtca tctcaaaaat
    56761 gccttttatt ggaatttaat attttctgta tttttaattt atagaaaaaa taaagaaaca
    56821 tgctgatagc tga
//
LOCUS       DARYSY010000005        55689 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYSY010000005 DARYSY010000000
VERSION     DARYSY010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55689
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..364
                     /locus_tag="TVR04_000228"
     CDS             <1..364
                     /locus_tag="TVR04_000228"
                     /inference="COORDINATES: protein motif:HMM:NF037889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268947.1"
                     /translation="FSKTRFDDSTLEEISGTLNGALEKYLESKNHRRIVLALSSLVES
                     CENEETKKRLRKIDSSRIQHLVNIRNDIAHGNIVSININDLEEIEFLARQMISIYYFG
                     ENFERYSLSSKKFNIQLW"
     gene            497..1291
                     /locus_tag="TVR04_000229"
     CDS             497..1291
                     /locus_tag="TVR04_000229"
                     /inference="COORDINATES: protein motif:HMM:NF013964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1268948.1"
                     /translation="MDRISNPNLNVVMEYAYLVIRSSTDTDQSLDVAFWLQDYYEDVL
                     ECWIKPQKVTAIHKYIEYIIDFFIGYALDKHFPIPEIKSMTSILDNYDIDYSKIGELD
                     ISEFGDSDSTEELEEYANQLFQFFIESAFDRFVNDVFNTLFWNKNFLYEFNLQCAQFI
                     CELNEENYSDLLKEEGVLKRTKYVPSWLKNAIIYRDKNRCSLCGCDLSKSHTTVTKEN
                     YDHIIPLQNGGNNDPSNWQLTCEQCNKSKGHRSSNFTNIVMPFWER"
     gene            complement(2070..2714)
                     /locus_tag="TVR04_000230"
     CDS             complement(2070..2714)
                     /locus_tag="TVR04_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1268949.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELR
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYETTQRLYQLIKSLEDKTYQQVLMVGHGAHLTAS
                     IRALLGFEPAMLRAQGGLDNASLTIIETLDFKHFHCLRWNDTSFLQKKATRVTP"
     gene            complement(2733..3098)
                     /locus_tag="TVR04_000231"
     CDS             complement(2733..3098)
                     /locus_tag="TVR04_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1268950.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GAFGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIIHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            complement(3095..3574)
                     /locus_tag="TVR04_000232"
     CDS             complement(3095..3574)
                     /locus_tag="TVR04_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1268951.1"
                     /translation="MAKKAKVKKTLVEQILDKEAISYQALRINALKGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            complement(3735..4298)
                     /gene="thiT"
                     /locus_tag="TVR04_000233"
     CDS             complement(3735..4298)
                     /gene="thiT"
                     /locus_tag="TVR04_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1268952.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFVLAKVYYLSLSQVIIEYILAFTSMGLAGLFSKPLAN
                     SLDTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVVFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     regulatory      complement(4345..4441)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(4770..5636)
                     /locus_tag="TVR04_000234"
     CDS             complement(4770..5636)
                     /locus_tag="TVR04_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1268953.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKPDKGAKQ"
     gene            5853..6368
                     /locus_tag="TVR04_000235"
     CDS             5853..6368
                     /locus_tag="TVR04_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268954.1"
                     /translation="MSTKVISRLAIVSVCCFLLRLAFSGFLIGQPVMALLLIYLLYVN
                     VAEAILAMTGYVLLLACFFGFGPWLFWQMACYSMVLVLWRYFLNPLSDRLSQHRLINQ
                     VLMAGVCTFCYHILLDSCFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKR
                     LSGKKGPKLSA"
     gene            complement(6567..7760)
                     /locus_tag="TVR04_000236"
     CDS             complement(6567..7760)
                     /locus_tag="TVR04_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1268955.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYIIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYTTSNVLDIVSNFVGS
                     VLLSFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFASFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALVYTTNATLYAVFGVLFLLIPFVYSNIRIIGVLINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8256..8759)
                     /locus_tag="TVR04_000237"
     CDS             complement(8256..8759)
                     /locus_tag="TVR04_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1268956.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGNATEINTFCSLTYHTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKRIEWNFAKFLIDQKGQVVERYASKTDPKMIETALQRLLFQ
                     EPIDQSD"
     gene            complement(8752..10551)
                     /gene="pepF"
                     /locus_tag="TVR04_000238"
     CDS             complement(8752..10551)
                     /gene="pepF"
                     /locus_tag="TVR04_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1268957.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVSLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSAAIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            10749..13532
                     /gene="ppc"
                     /locus_tag="TVR04_000239"
     CDS             10749..13532
                     /gene="ppc"
                     /locus_tag="TVR04_000239"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1268958.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALIKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQTRLSQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLIDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIVTNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSKRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            13740..15020
                     /locus_tag="TVR04_000240"
     CDS             13740..15020
                     /locus_tag="TVR04_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1268959.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFSVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIIDINQFQ"
     gene            15367..15585
                     /locus_tag="TVR04_000241"
                     /pseudo
     CDS             15367..15585
                     /locus_tag="TVR04_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681385.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            15674..16573
                     /locus_tag="TVR04_000242"
     CDS             15674..16573
                     /locus_tag="TVR04_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1268960.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKASFDQLFPFLAYQVEDERLVVEVTDSQTKHHILEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            16563..17303
                     /locus_tag="TVR04_000243"
     CDS             16563..17303
                     /locus_tag="TVR04_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268961.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPTFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
     gene            17296..17874
                     /locus_tag="TVR04_000244"
     CDS             17296..17874
                     /locus_tag="TVR04_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1268962.1"
                     /translation="MFSEMKRYMTYRVRYLFDSICDVIYSFIFITGIIVIVDSKAPIN
                     ILYFFTYYLITNVILLANEELEYEIRTNQYMNIKTTKQTTLMIYIYRSGPYFIWSALI
                     FLTSVSLAQVFFKGKWLFPTLTVLEVTLMLIVNGVVALVLYILAIKLTERFKRVSVFL
                     HLMNTLMLFYSGLVFPVPFFTYANVLDFIVGI"
     gene            18146..19702
                     /locus_tag="TVR04_000245"
     CDS             18146..19702
                     /locus_tag="TVR04_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1268963.1"
                     /translation="MKKLLSYLGRFRYFALLVFMLGGFSSILQSLVIQRVIAIDTVSD
                     FRSLWKLFIVGLLTYLLFYGLEFGANVVYDVACKRIMLALRDKLTRKLLLSGQAIDQH
                     EATNFLSQDLEFFYDNYVTQVMRLPKDGMIFLVVAIYLITLNPLLAFLFIVGSLLRPL
                     PQLFLTQTTESLGKRQSDERERSMSLIMDYVNGSSTLLHHQAFESTYDQLANQVLTYE
                     TARRNYYYLSNFLFFCNGLTQFLGRVVPIGLYFLLPMVFGHIPVSSLIAMFMASNNLA
                     NPLQNMMYATFSMQAAVSVKARIDDMMDQVADEAETPYVPYFKALALEGITKSYGAKL
                     ILKDFSYTFEQGKKYLIKGASGRGKSTLLHIIKGAAVDSGKIAFITKDKQSFENYQAN
                     VGMVNQAPFLFNGTLEENVCLNQEFSKEDILAVLDQVHLLEELPAGLGFQIENNGTNI
                     SGGQRVRIELARFLLRQKDILLLDEVTAALDKDNARRVRELIFSLPITIIEVAHHVDQ
                     AIAYDDMIEL"
     gene            19712..21274
                     /locus_tag="TVR04_000246"
     CDS             19712..21274
                     /locus_tag="TVR04_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1268964.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTSLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNHREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGRSTLTQNQALFASLKQVKKQSEHYESS
                     RQGFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDIFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGPSGSGKSTLFKLILQEMSPDEGTLDMVLAGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNYQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVNNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            21657..22758
                     /gene="prfB"
                     /locus_tag="TVR04_000247"
     CDS             join(21657..21728,21730..22758)
                     /gene="prfB"
                     /locus_tag="TVR04_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1268965.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            22809..23501
                     /gene="ftsE"
                     /locus_tag="TVR04_000248"
     CDS             22809..23501
                     /gene="ftsE"
                     /locus_tag="TVR04_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1268966.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            23494..24423
                     /locus_tag="TVR04_000249"
     CDS             23494..24423
                     /locus_tag="TVR04_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268967.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENYHKIYDQIAGIKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(24939..25580)
                     /locus_tag="TVR04_000250"
     CDS             complement(24939..25580)
                     /locus_tag="TVR04_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1268968.1"
                     /translation="MIIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHANLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            25918..28383
                     /locus_tag="TVR04_000251"
     CDS             25918..28383
                     /locus_tag="TVR04_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1268969.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIIEGKEIVDSYQT
                     DVNPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLCETAMIVRQALAVSRPYASSDYIKINQIL
                     LKKSAQPAKPYQLSQSFEINAALLALEERPKQLSFAKIVEETLSQGGATFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNRFDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRYAAYFDQIKHDGSI
                     QQTSPFYAYDFWQKNYQKAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAAPNSLLEQRLLEGIAFELNQLSNHYHQEEQQAQG
                     SQHLLRLQEHVKELGAAASQSLKQLFQQQEMDYWVSSEQQADKRQTFLNGSSRAVLQF
                     SSLLPEVFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMPLI
                     KDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGKNG
                     TAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQRY
                     LQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILHSL
                     EEEFLISQQNFHDSLAEIGDFLI"
     gene            28495..28884
                     /locus_tag="TVR04_000252"
     CDS             28495..28884
                     /locus_tag="TVR04_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1268970.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            28881..30092
                     /locus_tag="TVR04_000253"
     CDS             28881..30092
                     /locus_tag="TVR04_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1268971.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYTPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            30105..31451
                     /gene="asnS"
                     /locus_tag="TVR04_000254"
     CDS             30105..31451
                     /gene="asnS"
                     /locus_tag="TVR04_000254"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1268972.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKKYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            31752..32756
                     /locus_tag="TVR04_000255"
     CDS             31752..32756
                     /locus_tag="TVR04_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1268973.1"
                     /translation="MMNRKKHTKLIRNYSICSAVAVLAAVSLGTGQQVQASDSVRFPN
                     VRDYIQEEYNGDVEKLSRSLQIYFGNLKEYIEFQFENRNQGPAGPAGPRGERGPQGET
                     GPAGPAGPQGPRGETGPAGPAGQQGQPGEAGPAGPQGPAGQPGVQGPKGDKGDKGDTG
                     ATGPQGPAGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKGD
                     RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKKEPEKDTKPSVPKAP
                     DNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGLIASAGLLVFKRKKN
                     "
     gene            33284..34174
                     /gene="rapZ"
                     /locus_tag="TVR04_000256"
     CDS             33284..34174
                     /gene="rapZ"
                     /locus_tag="TVR04_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1268974.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNSNLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            34171..35148
                     /locus_tag="TVR04_000257"
     CDS             34171..35148
                     /locus_tag="TVR04_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1268975.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            35145..36056
                     /gene="whiA"
                     /locus_tag="TVR04_000258"
     CDS             35145..36056
                     /gene="whiA"
                     /locus_tag="TVR04_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1268976.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIKYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            36423..37820
                     /locus_tag="TVR04_000259"
     CDS             36423..37820
                     /locus_tag="TVR04_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1268977.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVFRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETVGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HETDLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            38056..39606
                     /locus_tag="TVR04_000260"
     CDS             38056..39606
                     /locus_tag="TVR04_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1268978.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVAVIKGTGDMLLVAGSGHSHEHGHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKTAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGSWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGEKKTFTYKYAGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            39952..40680
                     /locus_tag="TVR04_000261"
     CDS             39952..40680
                     /locus_tag="TVR04_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1268979.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEGLTSDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEARLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPSKKI"
     gene            40692..41867
                     /locus_tag="TVR04_000262"
     CDS             40692..41867
                     /locus_tag="TVR04_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1268980.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWLEVFESFLKQKESLLA
                     FFDRIRESANGDKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLFYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     QRSYLFLMPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLETKKCYLDQIVAMVAAII
                     QQEADLQKLASLAFQRLVYLGSGVLAGLTQEAQLKILELTAGRIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFDL
                     DSSMLLPDAYLAFPLVFIAQTIALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            41877..42872
                     /gene="lacD"
                     /locus_tag="TVR04_000263"
     CDS             41877..42872
                     /gene="lacD"
                     /locus_tag="TVR04_000263"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1268981.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGALKRMMAAHQDTEP
                     APWQIESLKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRFKEAGADAVKFLLYYDVDGDEYINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSAKRFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQESASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEAAARQWLRTEGFQNIDRLNQVLEKTASPWTTKLTVDEA"
     gene            complement(42914..43633)
                     /locus_tag="TVR04_000264"
     CDS             complement(42914..43633)
                     /locus_tag="TVR04_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1268982.1"
                     /translation="MNIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLDTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDYHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            43773..45557
                     /locus_tag="TVR04_000265"
     CDS             43773..45557
                     /locus_tag="TVR04_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1268983.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDNVFVTGNFGSNASKQF
                     ASMQDFFQAYQKQWPLMCMEFWLGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKERYPQLS
                     FAEPMISSTMALESIKLSAKVSLFKTIKNVSAIKKSFYPCNMEELGQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDGVPGFY
                     AYDFDCQQPADTYLDLSQFGKGVALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYNDIKGENL"
     gene            45554..46039
                     /locus_tag="TVR04_000266"
     CDS             45554..46039
                     /locus_tag="TVR04_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1268984.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLGLIQKGVTISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            46085..46966
                     /locus_tag="TVR04_000267"
     CDS             46085..46966
                     /locus_tag="TVR04_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1268985.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLALATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            46953..47771
                     /locus_tag="TVR04_000268"
     CDS             46953..47771
                     /locus_tag="TVR04_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1268986.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGAIFWLLGRKGMSSTKAIVVIILFALVMSYFNILGV"
     gene            47775..48179
                     /locus_tag="TVR04_000269"
     CDS             47775..48179
                     /locus_tag="TVR04_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1268987.1"
                     /translation="MAQTLILISHGAFCRELKKSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEQLDFKAFACDNIHHVNTLISALADDDDD"
     gene            complement(48286..48546)
                     /locus_tag="TVR04_000270"
     CDS             complement(48286..48546)
                     /locus_tag="TVR04_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1268988.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(48671..49603)
                     /locus_tag="TVR04_000271"
     CDS             complement(48671..49603)
                     /locus_tag="TVR04_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1268989.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDIYGDLSYVDTKASSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYTFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDASGAARLL
                     LSQKVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(49613..50041)
                     /locus_tag="TVR04_000272"
     CDS             complement(49613..50041)
                     /locus_tag="TVR04_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1268990.1"
                     /translation="MWVVKAFDQLTRDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQKARRAGLGRDLVHQALAYCQQHFPK
                     IPIYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            50299..51324
                     /locus_tag="TVR04_000273"
     CDS             50299..51324
                     /locus_tag="TVR04_000273"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1268991.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSGTNLTKEYELFVKHFETSVSDFLEHNRDAIKASFASPAEKEALLARLDKA
                     YQSYIKK"
     gene            51385..51831
                     /locus_tag="TVR04_000274"
     CDS             51385..51831
                     /locus_tag="TVR04_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1268992.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            52159..52452
                     /locus_tag="TVR04_000275"
     CDS             52159..52452
                     /locus_tag="TVR04_000275"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1268993.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMALVDQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKAIMAVSRRYQAEQIAVGSNDDEAY"
     gene            52433..53665
                     /locus_tag="TVR04_000276"
     CDS             52433..53665
                     /locus_tag="TVR04_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1268994.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQITKQGMGLVFDVGHGEKAKLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFLGRLSHLKDRSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLVGNLFAFLLARAKPYIAARLSNPYYRVLLVGSILSLSLLLCH
                     YGRYSGLGTNLITAAFSHQTITNYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNAAAYFIVMAFAYMV
                     SRRYSIYTKQRVTTSIVS"
     gene            53811..54158
                     /gene="rplS"
                     /locus_tag="TVR04_000277"
     CDS             53811..54158
                     /gene="rplS"
                     /locus_tag="TVR04_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1268995.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKGQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            54673..54744
                     /locus_tag="TVR04_000278"
     tRNA            54673..54744
                     /locus_tag="TVR04_000278"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:54706..54708,aa:Arg,seq:cct)
     gene            complement(54871..55674)
                     /locus_tag="TVR04_000279"
     CDS             complement(54871..55674)
                     /locus_tag="TVR04_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1268996.1"
                     /translation="MSRSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDANQHIEEKNNLATEELDEAA"
BASE COUNT        15903 a        10642 c        12671 g        16473 t
ORIGIN      
        1 ttttagcaaa acaagatttg atgattcaac attagaggaa atttcaggca cactgaatgg
       61 tgcattagaa aagtatttag agagtaagaa ccataggcgg attgtgctgg cattgagtag
      121 tttggtagag tcctgtgaaa acgaagagac aaaaaaaagg ttacgaaaaa ttgacagttc
      181 tagaattcag cacctagtaa atataagaaa tgatattgct cacggcaata ttgtttcaat
      241 aaatataaac gacttagaag aaattgaatt tcttgcacgt cagatgatat cgatatatta
      301 ttttggagaa aactttgaaa gatattctct atcatcaaaa aaatttaata ttcaattatg
      361 gtaatactgc tgatggtgaa aggccatcat gttgatacga taacattgca tttgtgtttt
      421 ggaaattctt gacggattat aagcttgtgt gtttttgtgt taaaattatt gtaatattga
      481 agctatggag aaacatatgg atagaattag taatccaaat ttaaatgtgg taatggagta
      541 cgcttattta gttattagat caagtactga tactgatcag tctttagatg tagcattttg
      601 gttgcaagat tattatgaag atgtgttgga gtgttggata aagccacaaa aagttactgc
      661 gatacataaa tacattgaat atattattga cttttttata ggatacgctc ttgataaaca
      721 ctttccgata ccagaaatta aatcaatgac ttcaattctt gataattatg atattgatta
      781 ttcaaaaata ggcgaattag atatttctga gtttggtgat tcagactcaa cagaggaatt
      841 ggaagaatac gctaatcagt tgtttcaatt ttttatcgaa tcagcatttg atagattcgt
      901 taacgatgta tttaatacct tattttggaa caaaaatttc ttgtatgagt ttaatcttca
      961 atgtgctcaa tttatttgtg agctgaatga agaaaattat tccgatttac ttaaagaaga
     1021 aggggtcttg aagagaacga agtatgtacc cagttggtta aagaacgcta taatttatcg
     1081 agataaaaat aggtgctctc tttgtggttg tgacttatca aaatcccata cgacggtgac
     1141 aaaggaaaat tatgatcata ttattccgtt acaaaatgga ggtaacaatg atccatctaa
     1201 ttggcagcta acctgtgaac agtgtaataa gtctaaaggg cacaggagta gtaactttac
     1261 caatattgtt atgccatttt gggaaaggta gattcgttct ttaatataat cttgaattat
     1321 tccgaatcta tttcgttcca taatatgggt aagacctatc accacatgtg gagtgcgtag
     1381 tgttgctaca acgaagcaaa gggtaaaaat cctttatttt aagcactttt tcaagcattt
     1441 tgtctttatt gaaaagagtg attttgacat aaaaaaggtg caaaaaaagt acattgatgt
     1501 gaacgtctgt ttggatgtcg actgcgtgga caaaaaatag atatgtcagt aaatatttat
     1561 ggaactcgag agcatttgac tttttgtcaa ttgtgatgag tgactgataa ctagcaccta
     1621 gagagtacca gcttggtgct ctcttttatg atgttaaaag cattgggaat cttggtttta
     1681 aagtttttaa agcaaaatct tgctgtttca tgtccttata ttttaattgt gtgtattgtt
     1741 ttgtatagat gttactacaa gaaaatcatt gaaaatatct actgtaatcg ctactatcat
     1801 caggaaataa ctgttttgcg cgtttgtcgt ggttgaaagc cttaattagc ttgacaaatg
     1861 atagaaaagg actgagtcct gttcgataca gaattcagtc cttttttaaa atgaattgtc
     1921 aaacttttga ggttatccaa ttggtcctct tgtgtatcta gcttttcaca actttctaca
     1981 gctaataaag cgtccctcaa aaaatgggat gtgctctctg actaatggag tatagtttag
     2041 ctgtcttgga gctttgtgct taagagctac tagggtgtta ctctagtagc ctttttttgt
     2101 aaaaatgatg tatcattcca ccttagacaa tgaaagtgtt tgaagtccaa ggtttctatg
     2161 atggtcaggc tggcattatc cagtcctccc tgtgcccgaa gcatagctgg ctcaaagcct
     2221 aaaagggccc gaatggaagc tgtcaaatgg gcgccatgtc ctaccattaa aacctgctga
     2281 taggtcttat cttccaaact tttaatgagc tgataaagcc tttgtgtggt ttcataaagg
     2341 gattcagcct taaattgact gggcttgaat ttggctaaat tgtgataaaa ggctgacatc
     2401 tgactggggt agatggcgga tacagttgct attttggttc cttccagggt gcctaggttc
     2461 cattctctca gctgcttggt ataactaata tcagtcttgc agttagcttc gtccacaata
     2521 atgcgagcag tatcaacagc tcttttgagg tcgctggagt agatcgcatc aaaagaaatg
     2581 tcccgcagct ctcttgctag ctggcgcaaa tcgtccttag agctttcaag caagggcgaa
     2641 tctccgttag ctccctgaaa acggccctct aggttccaca aggttttacc atgtctgaca
     2701 aaatacaatt tcataagtct tttgcttcct aattaaatgt cataaatgat ggctccaaaa
     2761 ggaaagaggc taatcttggc taattttaga gattgccggg caaatggaat gccaacaatc
     2821 gtgaggcaca agagaagggc agaagtcaaa tgtatgatcg ctaagctcca gccacagcag
     2881 acaatccaga tgatattgag cagcaggctg cctgctcctt ggccaatttc gatggctttt
     2941 ccaaaaggaa aaagaccaaa agcgcctatc ttgaagcatt gtatcccaaa aggaatcccg
     3001 ataattgtta agcataggat aagcccaaca atagaccaag agatccaggc ccaaaagcct
     3061 gaaaaaataa accaaatcat atttccaata agtctcattt gttctccttt atgtcagcaa
     3121 agctagcccc aacaaaatct gctagggctt gactattgat ctgtatggat cgaccaagct
     3181 caccagctga tacaataatt tcttgcttgg ctagtgcaga ctggtcgatg taaataggat
     3241 aattgtgcct ttgtcgaata ccaactggat tgtttgcacc atgaacatag ccggttattt
     3301 tttgcagctc cttttgagga atcatggaga cctttttgtt tccagaaagg cctgctagct
     3361 tcttttcaga taaatgctct gtcaaaggaa taatcccaat caaggggcct gtcttatcgc
     3421 cagtcagtgc tagggtttta taaatatctg atgggttgat tgtgtctggg aaatcacctt
     3481 ttagggcatt gatcctaaga gcttgataag aaatagcttc cttatctagg atttgctcca
     3541 ccagcgtttt ctttactttt gcctttttag ccatttgtta acttccttat gtgtcaatat
     3601 caaaaacagt ctaacagtag tagtatacca ttagactgaa aaaaagtctt ttttgatcct
     3661 ttttctaagc ttagaaagag caggccttta cagacctacc tcagctttat gattttcaga
     3721 ttcgaactct tgtcttattt actaggctta aaaaattgtg gttgcgtcgg taggataatg
     3781 agcagggcaa taagggtcac gataaaagtt agaagacctg ctgtgccatt gacagtaaag
     3841 gaataccaaa tagcagaggt gcccttagga gcatagctcc cccagaaaac aacaccagcg
     3901 ataaaatgcc agatataacg aaccccaatt gctaaaaagg ccgctgcgct agcaattaga
     3961 aggctgaagg atcttttgtt ggtgtcaaga ctattagcca agggcttaga aaatagaccg
     4021 gccaagccca ttgaggtaaa agcgaggata tactcaataa taacctgaga cagactgagg
     4081 taatatacct tagctaaaac aaaatgcagc agtccccaaa tcaagccagt tagcaggcca
     4141 taccttaggc cacgcctaag cgaaaataaa acgagaggaa tagcaccata agaggggcta
     4201 aaccagccgg caaaatctgg tataaatgat aaagccatag caagagcagc aaaaatagca
     4261 gcctcaatca gaacggtaac agttgtcttg tttgacataa aaaaactcct tttgcacaca
     4321 aaaagagaat cgttttccaa tgctaatgat attggtcaca atccctacgc ttgtattaac
     4381 aagatcaggt ccttaggatt tcgcatgcgc gatctcagcc aaagcactcc tttgtgataa
     4441 ttatattttc tataattata aaatgagatt gcagcaatgt caagaatttg gcctggaaat
     4501 catgaaacca agttaacata gcggtattgc caaaaactga tcataccaaa aaaggccgat
     4561 ctcacagcca gcctctaaac caaaaacaag caataattga tgttatcaat atcagattct
     4621 agatacagtt gtccttaatg ctcaaattga cgtcagaagg ggtacaacat aaaggttaaa
     4681 gcgttttgct ttaaccttta tttattgtgt taatgcatat tgaaatgaca tgcagttatc
     4741 agggatgaca agtaatgctt agttactggt tattgttttg cgcctttgtc aggctttact
     4801 ttcccaaaaa gcttttcaaa ggttttttta gtgtcttttg tgacagcgat ttgatttaaa
     4861 tctaatggat tgttaaagcc attgaggtag ccttgcgagg tgtattgatg caggtcgtaa
     4921 tctaggctgg tgtctggggc tgcctcatag tagccggaat caccaccata ggtaggaatc
     4981 cagatagcgt caaagccttc tgttgaaatg tcctgctcag ccataaaata agtgccgata
     5041 tacaggccaa cattttctgc acctaaccgt tttagctcct ctctaaatgc cttgacccct
     5101 ttattcatgt ccgtcatggt agcttcttca acatcaatcc aataataggt tggattaaag
     5161 ggagaagcgt ttttgtaaaa ggttcttgct tcagcccgca tttccttagc actacgacca
     5221 agagcatagc tatagacagc aactgggata tgtcgttttt gaaattctgt aatgtgcttt
     5281 ttaaatgatt tatcaatccc agtagtaaag gcagcattat tatgggcagt aatttgtgat
     5341 ccgccataaa cacgaacaat tgctgcagaa atattagatg ctaaaaggtc atagtcaatg
     5401 tcacttggca gctgccagcc agaaacatca ataatggggt ttagtagaaa ttcagtagtt
     5461 tcagatgtgc ttgtagtcga cttattggac gtgctagtgt tagtgggaat gcttgccttg
     5521 gcaagcttta gctctttact tttgagatta tcagaatgag cctttccaat gattaacaaa
     5581 gtagcaatca gcgtaaagaa gaccacaaca acaataggtt ttattcttct tctcatcagt
     5641 cttattgtac cttaaatgct tcaaaaaatc aaagtggtct tacgattttc ttaggttttt
     5701 agctccttag gacagctttg gcagatcagg tcctatctat tttcgtttga ttttagtcta
     5761 cctgtcttgt aatcatctat caaaaagctg ttgaggctgg tcaagagatg caaaatctgt
     5821 cataatagat aaaaaacact caaagaggga ttatgtctac caaagttatt agtcgactag
     5881 ctatcgtttc tgtatgttgc ttcttgctgc gcctagcctt tagcggcttt ctcattggcc
     5941 agccagtcat ggctcttttg ttgatttacc tactctatgt taatgtagca gaggctattt
     6001 tagcgatgac gggctatgtg ctcttattag cgtgcttttt tggctttggt ccttggctct
     6061 tttggcaaat ggcttgttat tcaatggtat tggttttgtg gagatatttc ttgaatccct
     6121 tatcagacag gctatcgcag cacagattga tcaatcaagt cttaatggca ggagtctgta
     6181 ccttttgcta tcatatactg ctagatagtt gttttgctta cctctatagt atctcttggt
     6241 ggagctatat atgggcagga atgcttttta cagtgactaa tgccttagcc actatgggtt
     6301 atttcctggt agtgctttta ttgcttaaaa ggctatctgg caaaaaaggc cctaagctgt
     6361 cagcttaggg tcttaatgct ggctttgacg cagcaacccg gtagtagtgc agttgttgcc
     6421 gatcagtaat ctcttttttt tgcctcttaa atattctcat attgatggat aatttttgat
     6481 tatttaatag tgacttctga ttcttttttg taaggaagct tattttgttg aagggcttta
     6541 tccattttgc tggttttaga actaagctat tttctttctt gctgtaaatg gacgatgagt
     6601 aatccaaagc ctatcattat tgtcagacta ttgatcagga ctcctataat ccttatgttg
     6661 ctataaacaa agggaatcag taaaaatagg acaccaaaaa cagcgtataa ggttgcattg
     6721 gtcgtgtaga ccaaggcgag cttgttgtgg ttatactcac tataaatcat tttttcaaat
     6781 acattgcccg atatgccaat aatcgtgaag gtaatgaaaa acaaaagtaa ttttaccatc
     6841 ggatagggaa tcataaagca aagcaagaag ctgcttccag acaggatata atcaatgaaa
     6901 aagaagcttc gtggagatac cttaatgcga ggcgcaacca gagcccctaa taaatctgct
     6961 gctctgtgag ctgctaaaac aaggccaatg tattcgattg aaatgccttc agacagtaga
     7021 tacaagggaa ggagtgctag taataaatcg gttcctccgc tgagaaaggc ttctaccaag
     7081 atgataaagg aagcaaaggt agactctcta aatgcacgta gtgattctgt tacagaagca
     7141 ggtttttcaa tctcgtcgtt agtcgtggta ctaagcttag acgggctaag ctgaatccta
     7201 aaaataaaag ctatggctcc tataaagaaa ggcaggctca attgcagtaa aacgagatag
     7261 gaaacaaagc taagaagaac agagcccaca aaattgctaa caatatctag aacgtttgat
     7321 gtagtgtatt gaatatctac tgatttttca atgaggtctg aatcatcgtc tagtgttctg
     7381 ggaacgattt tcatttgaat ggtatttaat acggttgtga ccaagttaaa ggcaaggttg
     7441 agcacataca tgacaacaac cggtagctga tagcttaagc agatgataat actgatgatg
     7501 acaatgagct gtatcatctg aaagacaatt aaccattttt tatcattttt taagttatgg
     7561 attaaagaac cgtaagcaaa agacagcata tttggcaata aaccaaccaa tgtcaaaaaa
     7621 gaaagctctc ccgcgttaat gttgtaaacc ttaagtaaac caacagacaa agcaattatg
     7681 taaaaactgt ctgcgatatt gcgacttgac ctactaaaaa tgaggttata gaagttactt
     7741 gttaaccctt gaaatctcat gctgataaac tctccaatca gtacaatcta tttgaatgtc
     7801 atttgaaact cctgaggtca tttgcatgct gtccactgtg ataggattaa gggtaagggc
     7861 ttttggcagc acagcttaga ccattcaata gtcatgtgtt tttcttgatt ttataagatg
     7921 attttaacaa tcctaatcac atgccaatgc tttttactgt tgatgactga agtaaatgtc
     7981 cttaaatcat gtgaacaggt actttttgat aaagataaaa aggctagcat aagttatcat
     8041 tgctcaagtg caccagtcct tacaggaagc agcttgaatg atttgattga aaaaagtaag
     8101 cttaggtgtg aggacaagat ccccttcaaa aaagttcttt gaagaataga caagcaaata
     8161 gctgacttta gcagctcctt ggcaaagtaa gaagctttag atacaaaaac aagccaagaa
     8221 ataaggatct tggcttcttt tttgatagga tttagttagt ctgattggtc aattggctct
     8281 tggaagagca atcgctgtag ggctgtttca atcattttcg ggtctgtttt tgaggcatag
     8341 cgctcaacaa cctgcccctt ttgatcaatt aaaaattttg cgaagttcca ttcgatgcgc
     8401 ttgccgagtg ggccactttt ttgttccttg agccaagtga ataatggctc tgtctccttg
     8461 ccattaacct tgattttggc aaagcgtggg aaggtggtgt ggtaagttaa gctgcaaaag
     8521 gtattgattt ctgtagcatt acccggtgct tgatgtaaaa attgattgca ggggaaatca
     8581 aggatttcaa agccttgttc cctgtaggtg tcataaagct cttgtaatgc ttgatattga
     8641 ggagttaatc cgcatttagt ggcggtgttg accactaata ggacctttcc ttggtattgc
     8701 tccagtgaac aatcagtgcc atcttgtctt ttaacgctaa agtcataaat gctagtcatg
     8761 accaatttcc tctgtatagg caatgatctg atcaaccgta tcgctcaaga attgaatggt
     8821 atcgcgaagc ggcttgtctg ttgagatgtc agctccgatg agtagggctg tctcaagcgg
     8881 ggtacgactg ccaccagact ttaagaaatc aagccattcg ttggcaccat ttgggttatt
     8941 ctttagattg aggtagccgg cagtcgaaat cacaagccct gcagaatagg tatagctata
     9001 aagccccatg taataatgag cctgcctcat ccaggtaagg gcagcgtcat catcaatctc
     9061 aacagcatcg ccccagaact ctgttaaaac gtccttcatc atggcattaa gctgctctgc
     9121 accaaaggtg ccgccttctt cgatgagggt ataaacctta cgctgaaagg cagcctctaa
     9181 caaatgcgtg atgaagttgt ggaaataagt atctgtcagg cggtgcgcca gtgcaaagcg
     9241 tttttgacga ggcgtgtcaa attgtgcctc caaataatca cttagcatca gctcattgaa
     9301 ggttgaaggt gcttcaacgt aataggttga catgtgtgtg ttgaagtagc tttggtgatt
     9361 gtcagagaag ataaactgac cagaatggcc aatctcatgg atcagcgtgt aaacgtcaga
     9421 catacggcct gtccagctca tcagcacata agggtgaacc ttgtaagggt cagcagcgta
     9481 gccaccagaa tccttattgg catttgcagc aaagtccacc cagcgctctg tttggtagcg
     9541 ttcaacttct ttcgtatagg ctggaccaag tggtgctaat gatgccatca ccaagtcata
     9601 agctccatca atagagacct ctggattgag ggcgttatca atatctagct tccagtctgc
     9661 aaaagtcatc ttgtctaagc catttaccct tgccacatgc tttaagaatt tttgagcaac
     9721 tggaccaaat tcggtcatga tgaggtcgat ttgacggtca aacatgctgc ggtccacctc
     9781 ctgctcagcc agcaggtaat caaaaacaga cgcatagccc ttcatatcag ctaagagctt
     9841 ttctgatttg accttagcaa gataggctgc ggctgctgca ttttggtgct tacgcagtcc
     9901 gtttgagaag gaacgaaagg ccttgtcacg aatggcagca ttttcatggt tttgataaaa
     9961 gttttcatag gaaacaaagc tatttttgta gactttacca tcaacttcaa aatcctccat
    10021 ctcaaaatct ccagcccgca ttttggtgta aatgtcgtaa ggagcgttga tcacttctcg
    10081 tagattggtc agtgcctttt caacatcagg gcttagcaaa tgctcttttt ggattttcgc
    10141 catgcggata gctgcgctga aatagggatt tttttccaat tcatcaagaa cagcaaggtc
    10201 tgcattagct agggctgtat caaagaagct gagggctacg ctagccttgg tcatgaagtc
    10261 atcaccagcc tgggcaattt gagcaaatgc ttcatctgaa aaatcagtgg tctgtggcat
    10321 aaaggcatag gtgctaatat gactcatttg aatataaatc tgctcaatct ccatcaaggc
    10381 ctgtgtaaaa tcctgagcag ttgttaattt gccttcgtaa ttgcgttgga ataggctgac
    10441 atcttgtaag gctttttcaa tagccaatag aaaatcttcc ctgtctttgt agagggcagt
    10501 taggtcccaa agctcatttt cagggaattc tgaacgtttt tttaattcca taatgttctc
    10561 cttcatgagt aattacctat agtataacaa aaattagaag cgatagcctg taaaagcttt
    10621 acaaacattt ttgtaccaat gaatcttata tgtcaaggaa aacaaacatt cctagccaat
    10681 aggcttacat ttttagcaaa aagtggtatg ataggaggga aactagcata agaagggaag
    10741 tccgtcattt gtcagtcaaa aaattagaga gctataataa tcaggagatt attgctgaag
    10801 aggttgctat cctaaaggaa atacttgaga gcattacgcg tcgcatgatt ggtgatgagg
    10861 cctttgcaag gattgaggaa attatagacc tatctgaaaa acaggattat gtgcttctag
    10921 agcaattgat cgctaagatt agcaataaag atatggaatt tatttcacga tatttttcga
    10981 ttcttccgct gttgattaat atttcagagg acgttgattt ggcttatgaa atcaatcgtc
    11041 aaaacaatac aaatcaagac tatctgggaa agcttgctct gaccattgct tctgctgctg
    11101 aaaaggaaaa tgccaaggaa ctgttggaaa gggtgacggt ggttccagtc ttgacagctc
    11161 acccaacaca ggttcagcga aagacagttc tagagttgac caatagcatt cataaccttc
    11221 ttcgtcgcta tcgtgatgtc aaggcgggtg tcatgaatca aaacaaatgg tatagtgagc
    11281 tgtaccgtta cattgatatt ctcatgcaga cggatatcat tcgtgagaaa aagctcaagg
    11341 tcaaaaatga gattaccaat gtcatgcagt attacaatag ctctctgata caggcgatca
    11401 cagcgctaac aagcaagtat aagacgctgg ccaaggacaa ggggatcttg ctggacaatc
    11461 caaagccgat taacatgggc atgtggatcg gaggagaccg agatggcaat ccttttgtca
    11521 cagcagagac actgaggctg tctgcaacag ttcaaagtga ggttattctg cgcttttaca
    11581 ttgacaaatt gtcagctctt tatcaaacct tttcgctgtc atcagctttg ataaagacca
    11641 gtcctgaggt ggaacgcttg gctagcctat ccagtgatca gtccatttat cgtgagaatg
    11701 agccctaccg cagagctttt cactatattc agactcgtct aagccaaacc ctgcaggagc
    11761 taattggtca gccggcctca gaccagctag catctagaat gcctgctacg gtaggctcgc
    11821 ttcagtcggg cgttacaagc attgtgacca atagcagtga ccagcaagca ccagcctata
    11881 agacagcagc agcttttaag gctgatctgg tcatgattga gcaatctctc attgcagctg
    11941 gggattcctc cttggttgag ggggatttgc aagaggtcct acaagcggtt gatatttttg
    12001 gtttcttttt ggccagtatt gatctgcggc aggattctag tgtgcaggag gcctgtgttg
    12061 ctgagctttt gaaaaatgct ggtattgttg agaattacag tgctttgtca gaggagcaaa
    12121 aatgtgaggt cctcttaaag gagctgacag aagaccctcg caccctctca tcggcagctg
    12181 ttgaaaagtc agagctgtta gaaaaggagc ttgctatcta tacagcggca cgtgagctca
    12241 aggataagct tggtgaagag gtgattaaac agcacatcat ttcacataca gagagtgttt
    12301 ctgatatgtt tgagctggct atcatgctaa aggaggttgg tctcattgac caacgtcagg
    12361 cgcgcgtgca gattgtgcct ttatttgaaa cgattgagga tttggataat gctagagcga
    12421 tcatgacaca ataccttagc tatgatattg tcaagtcttg gattgttaca aatgctggct
    12481 atcaagagat tatgcttggg tattcagata gcaacaaaga cggtggctat ttggcgtctg
    12541 gctggacact ttacaaggcg caaaatgagc tgaccaaaat tggggaggac aatggtatca
    12601 gcatcacctt ctttcatgga cgtggtggga ctgttggacg tggtggcggt ccatcctatg
    12661 aggcgatcac ctcacagcca tttggctcta ttaaagaccg aatccgcttg acggaacagg
    12721 gtgagattat tgaaaacaaa tatggcaatc aagatgtggc ttactacaac ttggaaatgc
    12781 tgatttctgc ttctatcaat cgcatggtga ctcgcatgct gacaaatccc gatgagattg
    12841 atggctttag gaaaatcatg gacgaaattg ttgaagacag taagcgtatt tatcgagagc
    12901 tggtttttga caatccgcat ttctatgact atttctttga agccagtccg attaaggagg
    12961 tatcaagctt aaacattggt tctcgccctg ctgcccgaaa aaccattaca gacatctcag
    13021 gcctgcgtgc cattccttgg gtattttctt ggtcacaaaa ccggatcatg cttccaggct
    13081 ggtatgcagt aggctctgcc tttaagcgtt ttattgataa agaagaggga aatttagcca
    13141 aattacagca tatgtatgac aaatggccgt tctttcattc cttgctgtct aatgttgata
    13201 tggtattatc aaaatcaaac atgaacattg cctttcaata tgcgcagtta gcagaaagca
    13261 aggaggtctg tgaggtcttt cataccattc ttgatgagtg gcagctgact aagaacgtta
    13321 ttcttgctat tgcacagcat gatgagcttc ttgaggaaac cccgtccttg aagcaaagct
    13381 tggatttccg cctcccatat tttaatgtgt taaactacat tcagattgag ctgattaagc
    13441 gtctgcgtca tgagcagcta gatgaggact atgaaaagct gatccacaca accattaatg
    13501 gtattgctac aggacttcgt aattccggct aagccgttga agatcagtca gcagctcaca
    13561 cagacaggct actaggtcat agtggcttgt ctgtgttttt taggtggagt gattccaaga
    13621 atacagcaag ctttgtccag agccatgctt ggctaggtgc ttgcaatgta tttttccttt
    13681 gttttaccaa tgaaagatga tataatgcta atgattatct caagattata ggggaaatga
    13741 tgaaaattga taaaaggcat ttgctaaatt actccatatt actaccttat ctgattttat
    13801 ctgtgattgg gctgatcatg gtttattcca caaccagtgt tagcttgatt caggctcagg
    13861 ccaatccatt tcggtcagtt gccaatcaag ggctcttttg ggttgtcagc ttagttgcta
    13921 ttacctttat ttacaagcta aagttgaatt ttttgaccaa taccaaggtt ttaacaattg
    13981 ttatgctgct tgaaatactg ctgttgattg ctgctcgctt ttttacgaca gcgattaatg
    14041 gcgcgcatgg ctggattgtc cttgggcctc tgaggtttca gccagcagag tatctgaaga
    14101 tcatcatggt ttggtatctg gcactcacct tttcaaagat gcaggaaaag attcatcagt
    14161 atgattatca ggccttgacg cgtcgcaaat ggtggccaac agaatggggt gacctgcgtg
    14221 attggcgtgt ttattccttg attatgattg tgctggttgc tgcgcagcct gatttgggca
    14281 atgcctctat tatcgtgttg acagctatta tcatgttttc ggtcagtggt ataggctacc
    14341 gttggttttc tgccatttta gtgctaatta ctggtttgtc gactgctttt ttgggaatga
    14401 ttgctgtcat tggtgttgaa aaggtggcta agattccagt ttttggttac gttgccaagc
    14461 gctttagtgc ttttttcaat ccttttcgtg atttgacaga ttcgggacat cagctggcta
    14521 attcttatta cgccatgagc aatggtggct ggtttggcag agggcttgga aattcgattg
    14581 aaaagcgggg ctatctccca gaggcacaga cagattttgt cttttctgtc gtgattgagg
    14641 agttagggct gattggggca ggattgatcc ttgcgcttgt tttctttctt attttgagaa
    14701 tcatgaatgt cgggattaag gccaaaaatc cctttaacgc catgatggct cttggtgttg
    14761 gtggcatgat gctgatgcag gtatttgtta acattggtgg catttctggc ctcattcctt
    14821 caacaggggt tacctttcca tttttatcac agggaggaaa cagcctgctg gtcttgtctg
    14881 taggggttgg ctttgtcctc aatattgatg ccaatgagaa gaaagaggat attttaaaag
    14941 aagcagagct atcttaccgg aagtctgtcc gagaagaaaa tagtaatagt aagattattg
    15001 atattaatca atttcagtaa aaaagctcct tgtcaactgt tgcgggtggc ttatagctaa
    15061 tgtttagaga ggaccagatg ggtcttttct ttttgtcatc atagcacgaa attaaataaa
    15121 agaaaagcca gcgtttttac gcgctgacgg atagtgtggg cttatagttc taataccagc
    15181 cactcgttag acaaatggtt ataagtagcc tacaacgatg acaataattt cttctaatac
    15241 catcaaaaga agcattaaaa aatgacgttt gttcatgtga taatcctcac ttctgttttt
    15301 ctatagtgta tgttatgata gaactaatga taagtctttc ccgtatgtac aagtgaggtg
    15361 gtagttttga accattttgg aaaacttttt aagaaattta gagaatctcg tgggttgctc
    15421 ttgaaagatg tcgcaaaggc tggtatatca acatctcagt tgtcacgttt tgaaaatgga
    15481 gagactgatt taacgagttc taagtttatg agtgccttag atgagattaa tatgcctatt
    15541 gatgaattca tgtatgcggt acatgatttt catcgcgatg agttaatgga aaagtatgct
    15601 gtcaacgcag gggacgtgat tgacgtagaa gatacgattt taaaaaatct aatatcgcta
    15661 ggagtaatta ttaatgagtg acatcactat acggcatgtc aagaaaagct ttcatcatca
    15721 ggtagtctta gatgtgccta gttttgatgt aaagcgtgga gaaattgtgg ctattgttgg
    15781 tgcaaatggt gcaggtaaat caactttgat caaaatgatc tctggtttaa tgctgcaaga
    15841 cacaggatct gttttggttt atcatcataa aaatacttca gcagctattc atcgtgatgt
    15901 gaaatttgtc ttagaaagtg gtaggggcta ttacgagtat ctgacagcaa accaaaatat
    15961 tgattacttt ttacatttga ataacctgtc acgcagccaa gtcaaagaag aattggcaga
    16021 gttgtgccaa aaattggctt ttaatcccta tactgatcgg ttggtttctg aattatccca
    16081 aggcacaaga caaaaattgt ctttgattat tgctcttctt tgtcagccca aggttctgtg
    16141 cttagatgag ccaacaaatg gtctagatgt ggttgcaaaa aagcaatttg caaccttgtt
    16201 gcttgagctt agtcaaaaaa agcaaacgat tatcctgatg acgactcatg atatcttttt
    16261 tgtaaaagag ctatcagcaa gaatttgtgt catgagtaaa gggaagatca aaaaacaggg
    16321 gagtttttca gaaattttcg gagaaaacaa cacgtggatg aaatatagaa tcggtatccc
    16381 taagtttgag aaggctagtt ttgatcagtt atttcctttc ttagcttatc aggtagaaga
    16441 tgagagatta gtcgtcgagg tgacagatag tcagacaaaa catcatatcc ttgagcattt
    16501 tgagattata ttttttgaag aggttgaaaa aagcatcgaa gaactattat atgaggttat
    16561 tactgatgat taaagaaata caaagggagt tgaaaagaca attgcaggag atgatgcaat
    16621 tcaaattcaa tttatttttt gcaaactttg gtattttgat catggtgtca tcttatcttc
    16681 actattttga agatacgcag agtcagttct tgttattatg tctattattc acttggtatt
    16741 ttacgagtca tagcctcaca catccaacct tttttattga agatgacctt tatgatagaa
    16801 cgttgatcag tgttattcag agcagcaaga gtgtttttca tgtccttatg cttaaaatta
    16861 ttgttcaact attggtggat ttagttaagg caatacctat tgttattatg ttatcactcc
    16921 ttaataatat tgactttcca gaaagtagct tgagggtgat gggaagcttt gttgcctgtt
    16981 ttttgacagt cattagtaca tacggtcttg gcttttgctt atccagtctc tgttttgtgt
    17041 ttaatcgtac ctccagtgtt actgcgttaa tttcttattt catgctatac tttaccggca
    17101 tactaacgcc attagatggc tcacttggtc ttattggaaa aatgttccct tattatgctt
    17161 tgagaaatgc tattatgtct ccttcatatc agagcgtatg ttggattgtg gcttacggta
    17221 tgatatattg gtcggtcggt acattattgt tttctagggc attgacaatg gctaaaaaaa
    17281 gagggagtct ttttcatgtt tagtgaaatg aaacgatata tgacttatag ggtgcgctat
    17341 ttatttgata gtatttgtga tgtgatctat tcttttattt ttattaccgg cattattgtg
    17401 atcgttgata gtaaagcacc gatcaatatc ttgtatttct ttacatacta tttgatcact
    17461 aatgtgattt tgctagctaa tgaagagcta gagtatgaaa ttcgtaccaa tcaatacatg
    17521 aatatcaaaa caacaaaaca gacgaccttg atgatttata tctaccgatc aggaccctat
    17581 tttatctggt cagcgcttat ttttttgacg tcagtcagct tagcgcaagt ttttttcaag
    17641 ggtaaatggc tgtttcccac attaactgta ttggaagtga ctttaatgtt aatagttaat
    17701 ggtgttgtag ccttggtttt gtatattttg gcgattaaac taacagaacg ttttaaaagg
    17761 gtttctgttt tcttgcattt gatgaatacc ttaatgttat tttattctgg tttagtattt
    17821 cctgtcccct tttttactta tgcaaatgtg ttggatttta tagtaggtat atgaggcata
    17881 gaagcgaagt tcaatgagaa agtctttttc agtcttgggg caacatcaat ttgaaataca
    17941 gctaaagaaa aggttaggtg tagacaatac cgttgtcatg acaagtcatc aaaatgatga
    18001 tagcttacat ctgttttagc atctttggcc tgtttcagaa tgaaatactc tttgtcaagc
    18061 atatgcaaaa tagatgagca gtttgacaat atactggtga ttgccgaggt ttagaaagcc
    18121 attatagaat cttttgagga gtgctatgaa aaaattatta tcttatcttg ggagatttcg
    18181 ttattttgcc cttctggtgt ttatgctggg gggattttct agtattttac aatcacttgt
    18241 tattcaaaga gttattgcca ttgatacggt atcagatttt aggtctcttt ggaaactctt
    18301 tattgtgggg cttttgacct atctattatt ttatggattg gaatttggtg ccaatgtggt
    18361 ttatgatgtg gcttgtaagc ggatcatgtt agctttacga gataagctga cgagaaagct
    18421 gctactatcg ggtcaagcaa tagaccagca tgaggcaacg aattttctta gtcaggacct
    18481 agagtttttc tatgataact atgtcacaca agtcatgcgt ctgcctaagg atgggatgat
    18541 ttttcttgtc gtggcgatat acctgattac attgaacccg cttcttgcct ttctttttat
    18601 tgtaggttct ttgttacgtc ccttgcctca gttatttttg acccaaacaa cagaatccct
    18661 agggaaaagg cagagtgatg agcgcgaacg ttccatgtcc ttaataatgg attatgtgaa
    18721 tggtagtagt actctattac atcatcaggc ctttgaaagt acctatgatc aattagcaaa
    18781 tcaggtctta acctacgaga ctgctcgtcg taactattat tacctgtcca attttctttt
    18841 tttctgtaat ggtctgactc aatttttagg tagagtagtg ccgattggcc tttatttttt
    18901 attaccaatg gtttttggtc atatcccagt atcgtcactt atcgccatgt ttatggcatc
    18961 aaataattta gcgaatccct tgcaaaatat gatgtatgcc acttttagca tgcaggccgc
    19021 agtctctgta aaagctagga ttgatgatat gatggatcag gtagctgatg aagcagaaac
    19081 tccttatgta ccatatttta aagctctggc tttggaaggg atcacaaagt cctatggcgc
    19141 caagctgatc cttaaggatt tttcctatac ctttgaacag gggaaaaaat atttgataaa
    19201 gggtgccagt ggtagaggta agtcgactct gttacacatt attaagggag ctgctgttga
    19261 ctcaggtaaa atagcgttta tcaccaaaga caagcaatca tttgaaaact atcaagctaa
    19321 cgttggcatg gtgaatcagg ctccttttct ctttaatggc accttggaag aaaatgtctg
    19381 tctgaatcag gagttttcca aggaggatat ccttgctgtc ttggaccaag ttcacctgtt
    19441 ggaggaatta ccagctggtc taggctttca gatagaaaat aatggaacca acatttcggg
    19501 tggccagcga gtgcgcatag aattggctcg atttttgcta cgtcagaagg atattttatt
    19561 gcttgatgag gtcacagcag ccttggacaa ggacaatgct cggcgagtaa gggagctgat
    19621 tttttctctt cctattacca tcattgaggt ggctcatcat gtggatcaag ctatagctta
    19681 tgatgatatg atagaattgt aggtgattaa gatgtttaag tattttaata aatatctagt
    19741 gacactaacg cttgttgcat gtgccttaaa cagtcttgtc tttctgattg aacccttgat
    19801 cactagtaag atttttgatt taacgtcctt aaataatcat caagacacct tgtccttttt
    19861 aggctatggt ctgaccttat acgtggtctt atattctgtt atgttcattg ctaatcttct
    19921 gatcaaccat atcatgacga ttgggtgtgg tagaatcagg ctgcgtctct atcagaatct
    19981 aatcttaaat catcgggaga tgagtcatga caagaaaatt tctatgctga ctcaagatgt
    20041 agaatattat ctatggaatc acatcagccc tagcattctt ctcgtatcac acgtgagtaa
    20101 tgtcctcctg ctcagtgctt acctgttatc aaaaaacatg ctaattggtc ttatttttat
    20161 tgcatgtgct tttgtatttt tagtggttca gcatgtgatt ggtcaaaagg cagagcaaaa
    20221 aggtagtgag ctggcagtag cgagacaaaa gctgcttggc ttattaagtg atgtggttgc
    20281 ggggcgttcg acattgactc aaaatcaagc tctttttgct agcctcaaac aggtaaaaaa
    20341 acagtcagag cattatgaga gctcacgtca aggatttgag atatttaggt ctttctttac
    20401 cctattggca catctgatgc tgtttatttc tcaatttttg cccatttttt taggcttagc
    20461 cttaacctta ttaggtgtta agctgagaac aactgatctt attgccatgt ttattgcagc
    20521 aacacgctta gaacagccac tcaaaaatat tgttgatgat atttttaggc ttaatggtgc
    20581 aaaagccatt gccaagcatt ttgagacact tttagagcag cctattccaa aataccagtc
    20641 gcatgctatg acaggtgatc cttttgaatg tttagatggt catcatctgg cgaaatcatt
    20701 tgcaggtagg accttatttt ccgatctctc ttttcatttt gagaagggaa aaaaatactt
    20761 gattaaggga ccaagtggat ctggtaaatc cacactcttt aagcttatct tacaggagat
    20821 gagtcctgat gaggggacac tagatatggt attggctgga ggtcagacga ctgataatta
    20881 ccaccatcgc atagggctga ttgcgcagtc gccttatctt tttaacgata gcattcggta
    20941 taatttgacc ttgggggagg cgttttctga tgagttgctt ttagaaaagc tagaacaggt
    21001 tggtttgact gatgaatttg acgatatttt aaactaccaa attgttaata acggagaaaa
    21061 tatctcaggt ggtcaaaaga cacgtcttga aatcgcaaga agcctcatta gacaaaaaga
    21121 tgttcttcta gcagatgaag tgacggctcc acttgatgtc aacaatgcta aaactatccg
    21181 acagctacta tttagtttac cggtaacagt tattgaaatt gctcatcata ttgatgacac
    21241 ctttatctat gacggtgata ttgatttatc gtagaaaata tcatcacatt gcttagaaat
    21301 aataattaat gcttatgaaa ttgtcattca cctagtgaat ggctttttct tgtgataaat
    21361 gctccatgta aagctggata tgataggcaa tctgaagaaa aaagctaaca acagccatgt
    21421 tttttggggc tatgactgtt ctaatacgag ctgcctatag ctgctggttt ataataaatg
    21481 acataattgt cacaattcgt cattattttg tcgctaagtt tttacatagt tttcttatgc
    21541 tagttatagc agagctgctt ttcctaaaaa gaaaggaatt tagctgatgg gaaatagcaa
    21601 ttctaaagcc tttatgataa aatgaaaaaa gacactataa tagaagaggt aactgtatgg
    21661 aagtggcaga aatgcgccag caaatagtag aaaacaaaga gaagttgact agcttcagga
    21721 ggtctctttg acttagaacg cttggaggag gatatagctc ttttagaaaa taagatgaca
    21781 gagcctgatt tttggaatga taatatggcc gctcaaaaaa cctctcagga attaaacgag
    21841 ctcaagctca cctatcaaac ctttcatgat atgcaggaac tatctgatga gacagagctt
    21901 tatttagaaa tgcttgacga ggacgatagc gtcaaggaag agctagaagc aagcctgatt
    21961 aagctcagcc agatgctagc aagctatgaa atgacgttgc tcttgtctga gccctatgat
    22021 catagcaatg caatcctaga aattcaccca ggttcaggtg gcactgaggc acaggactgg
    22081 gcagatatgc tttttcgcat gtatactcgc tttggaaatg ccaagggctt taaggtagaa
    22141 actctggact atcaagcagg ggacgaagca ggaattaagt ctgtgaccct ttctattgaa
    22201 gggccaaatg cttatggctt cttaaaatca gaaatgggag tgcatcgtct ggtgcgtatt
    22261 tctccttttg actctgctaa gcgtcgccat acctcctttg tttcagttga ggtcatgcca
    22321 gagcttgatg atactattga ggtggagata cgtgatgatg acatcaagat ggataccttc
    22381 cgctcaggtg gtgctggtgg acaaaatgtc aataaggtct caaccggggt acgcttgact
    22441 catattccaa caggaatcgt agtggcctca acagttgacc gcacccaata tggcaaccgt
    22501 gatcgcgcta tgaaaatgct tcaagccaag ctttatcagt tagagcagga gaaaaaggca
    22561 gaagaggtca atgccctcaa gggagataaa aaggagatca cctggggcag tcagatcagg
    22621 tcctatgtct ttacgcctta tacgatggtg aaggatcatc gtaccaattt tgaggtggct
    22681 caggttgata aggtgatgga cggagatatt gagggtttta ttgacgctta tctcaaatgg
    22741 cgcatgggtg aggattaaag tgatccccac tcagataaac actaacagct tagagaagga
    22801 agaataagat ggcattaatt gaaatgaagg gtgtttctaa gaaataccgt cgctcgacaa
    22861 cagctctgag agacattaat gtctcagtca atcaagggga atttgtctat attgttggtc
    22921 catcaggagc tggtaaatca acctttatca agcttcttta tcgcgaagaa aagctaagct
    22981 caggcagcct aaaggtgggt gagtttgact taaccaagct aagaggacgt gaggttccaa
    23041 ttttacgtcg cagcattggt gttgtttttc aggattataa gttgctccct aaaaaaacgg
    23101 tctttgaaaa tgttgcctat gctatggagg ttatcggaga gagacgtcgc catatcaaaa
    23161 agcgtgttcc tgaggttcta gaccttgtcg ggttaaagca taagatgcgc tcctttccca
    23221 atcaattgtc aggtggtgag cagcagcgtg ttgcgattgc acgcgctatt gtgaacaatc
    23281 ccaagctcct cattgcagat gagcctacag gcaatttgga tccggaaatt tcttgggaaa
    23341 tcatgcacct gcttgagcgt atcaatctac aggggacaac gatattaatg gcaacgcata
    23401 acagtcatat cgttaatact cttcgccatc gcgtggttgc gattgaaaat gggcgtattg
    23461 tccgcgatga ggagaaagga gactatggtt acgatgatta gacatttttt ccgtcatatc
    23521 tgggaatcta tcaaaaattt aaggcgtaat ctcctcatga cctttgcgtc agtcagtatg
    23581 gtgaccgtca ccttaaccct gcttggggtc tttgctgcaa ccctgctgaa cattcaacgt
    23641 gtcgcttctg gcgtggaaaa caacattcaa atcaatgctt atttgcaggt tgattcgaca
    23701 gatgctgcca aggtggttca gtcgattaat ggagagcagg tgaataacga gaattaccat
    23761 aagatttatg atcagattgc agggataaag ggcgttgaga ggattatttt ctcaagcaag
    23821 gacgagcagc tgcaaaagct acaggatagt ctgggcgatg tctggggcat gtacaacgag
    23881 gatagcaatc ccctgcaaga catctatatc gtggaaacca agacccctaa gcaggtcaaa
    23941 tcagtcacta aggctatcaa aaagattcaa gggattgaag atgcggacta tggtggtatc
    24001 aattcggata agctctttaa gttttcaaag ctgatccaaa catggggcat tattggaaca
    24061 ctgttgctct tgtttatcgc aatctttctg atttccaata ccattcgcat gactatcatg
    24121 tctcgtcagc gcgatattgc gatcatgcgt ctggttggtg cgaaaaattc ctatattcgt
    24181 ggcccattct tttttgaagg ggcttgggtt ggtctgcttg gtgcgatatt gccatcgttg
    24241 attctttatt atggctacga gtttgcctac aagcatttta ccccggaatt gcagcataat
    24301 agcctgtcta tgtaccctat caatccatat gtttattact tgattggtct gctttttgtg
    24361 attggtatta tcattggatc actagggtca gtcttatcta tgagacgcta ccttaagttt
    24421 taatctaaaa gagccttttg cctgtgtgcc tcggctggca ccttgcagca agagctcttt
    24481 tttgtttgtc taggcaatac gtgctaggta aacaacaaca gaggctggga caaatgagct
    24541 gcactttagc aatcctcagc ggattcgtct cattcattaa aaagcgaaca agactagcct
    24601 tctgtatctc agaaaacttg tcttgttcgt ttgttttatt tgggatcagc cttttgcccc
    24661 agttttgatg ttatggctaa tgtagatgtg tttagatagc aaaagcagcc agcacttgag
    24721 gtgccctatc taggacttca gctacagcct ttctggcagg ctggcacacc ttcaaatagc
    24781 actgatttgt cggaccatga ggagatcctc tgcttgtggt agctggcttg tgttgagtga
    24841 taggtgctaa gtcagattag cagtctttat ggactgaagt catagctttt gctgctgcga
    24901 ctggttgggc atagactggg catctcggta gcttgagctt atcgctgcct cagaaaggga
    24961 ttgctatttt tttcatggct aatggtggta gctgagccat gccccggata aatctgataa
    25021 tggttaggaa gtgttagcag cttatcacga atgctagcaa gcagctgttc aagatttcca
    25081 gtcggcaaat ctgttctacc gatgctttct ctaaacagag catcgccagt aaacaccgcc
    25141 tcctcctgct caaagataaa ggaaacacca ccggcagagt gtcctggtgt tggcactact
    25201 gaaaagtgaa atccagccag ctgataaggt gtctgatact gaaagagctt ttctgctggt
    25261 ttgcagatga tatcaggcag attagcgtga cgtatcagcc ctgacaggtt catttctggt
    25321 ttataaagcc agtccgcctc ctccttggca acatagacag gagggtgctg gcagctctct
    25381 ctcaccagct ctaggctcat aatgtgatca taatgcgtat gagtcagtag aatagcagca
    25441 acaggcttgt tgatggcatg gatttgtgat aaaatagcct gccccttgct tcctgggtca
    25501 atgactaaaa tagcctcgtc attgacaaga aggtaagtgt tttcacccgc aacgggattc
    25561 atcagtgtca taataatcat acccttagtt taccaaaatc tgactcaaaa gacagctcaa
    25621 aaccacctct tttgataaaa gtgatctgtt taatggtttt gatggctaag ccaagatagc
    25681 tccagcttaa aggctgcttt ttttaattaa taggagcaaa aaggagctgc ctcagcgcta
    25741 acagctaatc agagtattag ctctctagtg tcatagcaag gaagtaggct ggggcgatta
    25801 aaaagcttga taactagccc tttatgatac tgactggccc tattgagctg agctaagggt
    25861 gggcattgtc agatttaggc aaagcctgtc acaaaacgtg ctataataga tagtactatg
    25921 atcaatgagt tttcacaaaa atatgctgtg attgacctcg aagccacaag cccaggtcca
    25981 acagcgtcta tcattcaggt tggcattgtg attattgagg gaaaagaaat agttgattcg
    26041 tatcaaactg atgttaatcc tcatgagccc ttgtcagacc atatcaaggc actcacaggt
    26101 attacagacc agcagctagc tcaggcaccg gacttctcac aggtagcaag aaccattttt
    26161 gagttgattg aggactgtgt ttttgttgct cataatgtca cctttgatgc caatttgttg
    26221 gcagaagctt tgtttttgga gggctatgac ctcctcactc ctagagtgga tactgttgag
    26281 ctggctcaga ttttttaccc cagcctagaa aaatacagcc ttagccacct atcagaggtg
    26341 ctagacctaa acctatctga tgctcatacc gctattgctg atgctcaggc gactgctaac
    26401 ttatttatca agctgcttca caagatagag agcttaccaa gagaatgctt ggagactctt
    26461 ttgctgtatg ctgatagtct gttatgtgag acagctatga ttgtgagaca agcccttgca
    26521 gtcagtcggc cttatgcttc aagtgactac atcaagatta atcagatctt gctaaaaaag
    26581 tcggctcagc cagcaaagcc ctatcaattg tcccagtcct ttgagattaa cgctgccctc
    26641 ttagcgcttg aggagcgccc taagcagctc agctttgcaa agatcgtcga agagaccctt
    26701 tctcagggag gggcaacctt tattgaggct caggcaggta ttggtaaaac ctatggctac
    26761 ttactgcccc tccttgcaca gaagcatcag acccaaatct tggttagtgt gccaaccaag
    26821 ctgctacagg accaaatcat ggctaatgag gtgagggcta ttcaggagca gtttcacatt
    26881 gattgccata gtatcaaggg gcctgctaat tacatcaagc tagacagctt tcaagagagc
    26941 cttaatcggt ttgatgacaa ccgcttggtt aatcgctata aaatgcaatt gctggtttgg
    27001 cttttggaaa caaggactgg tgatttagat gaaattaagc aaaagcaacg gtatgcagct
    27061 tattttgacc agatcaagca tgatggcagt atccagcaga cctcgccctt ttacgcttat
    27121 gatttttggc aaaaaaacta tcaaaaagct aagtcagctc gcctgctgat caccaatcat
    27181 gcctattttt tacaccgtat tcaggacgat aaggcctttg ctaagggcaa gatcttagtc
    27241 tttgatgaag cccaggcctt aatgctgcag ctagaggagc tagcccatca gcgactaaat
    27301 atagctgata cgctccaaga gcttcaagag cagctagctg cgccaaacag cttacttgaa
    27361 caacgcttgt tagaaggcat tgcctttgag ctcaatcaat taagcaatca ctatcatcag
    27421 gaagagcagc aagcccaagg ctcacagcat ttactgcggc tgcaagagca tgtcaaggag
    27481 ctaggtgctg cagcctctca gagcctcaaa cagcttttcc agcagcagga aatggattat
    27541 tgggttagca gtgagcagca ggctgacaag cgccaaacct ttttaaatgg cagcagcagg
    27601 gcggttcttc agtttagctc actgttgcct gaggtcttta aggcttactt tgtctcagct
    27661 actctacaga ttagccctag cattagcttg gctgatttat tgggctttga cacttattct
    27721 tatcatcagc tggctaagga gaagagcact cagcaattgg ttgtcattga tcaggacatg
    27781 cccttgatta aggacttgac tgatgaggcc tacacacaga ccatagcagc aaggctatta
    27841 gtgcttcatc agcaacagca ggtacctatc ttagtgctct ttaatgctaa aaagcacatg
    27901 ctcatggttt ctgactattt agaggctaat caggtgcagc acttgacaca aggcaaaaac
    27961 ggtacagcct atcacatcaa aaagcgcttt gatcgtggtg agcaatcaat gctgctgggg
    28021 cttgcagcct tttgggaggg agttgacttt gttcatgctg atcgcatgat agaggtcatt
    28081 acccgcctgc cctttgataa tccagaagat attgccactc aaaaaatgca gcgctaccta
    28141 caggcagcag gcaagcagcc ctttaatgat tattttctgc cgatgacgat cttaagatta
    28201 aagcaggcga ttggtcgaac cctgcgtcga aaagagcaga aatcagcagt tttgatctta
    28261 gatcgtcgca ttctgaccat gtcctatggt cagaccattt tgcacagcct agaagaggaa
    28321 ttcctgatat cacaacaaaa tttccatgat agtctagcag aaataggcga ttttttgata
    28381 taataggaaa gatcatatgc aaaggagctg aaattggaca agcacacaag gctcaaaaca
    28441 gttttatatc aatgtgccag cttggtcgta ctgctttgtc ttggagtgat gagcatgttt
    28501 tatcttgctg ttcatgatca atttgacaag aaatcaaggc tagccgagat tgcaaaatca
    28561 agagctggtg tcatctcaat tgatcatatt gattgctatc atggcactca gagttatctc
    28621 agtctttttg gaaaaaacaa ggcaggcaat accatcatcg tcacaataga ggagcaatca
    28681 gagcagctct tgcttagtcg ccctagcaat ggcattagtg ctaaggaagc acaggaaatt
    28741 gcctaccatg ccggagcaag gactattgaa gcagtgacat ttgggattga aaaccacaag
    28801 aggatttggg aggtggctgc tcaaaacggc tactatctga ttgatttcaa aaccgcaaaa
    28861 gtgatcaaaa aggaggtttt atgaccaagc tatcaaggcg cgtgttagca atggaagaaa
    28921 gcgtcaccct agcagcaggt gctagagcaa aggcattaaa ggctcaggga cgcgatattt
    28981 taagcctaac tctgggagag ccagatttta taacaccgca gcatatccaa gaaaaggcca
    29041 ttgaggccat caccactggt aaggcaagct tttacactgt tgcttcgggg ttgccagagc
    29101 tcaaggacgc cattgctgat tacatggcac gatcctatgg ttatactcct accagacagg
    29161 agattgtagt ggggacaggc gccaaatacg ttttgtatgc ctttttcatg gctgttttaa
    29221 atcctggtga tcaggtgttg attccgactc cttattgggt ctcttatgct gatcagataa
    29281 aaatggtgga cggggtgccg gtctttgtac agggcttgga ggaaaatcaa tttaaggtca
    29341 cagtagagca gctagaggct gccagaactg atcaaacaaa ggttgttttg atcaattctc
    29401 cgtccaatcc aactggcatg atttacagcc gacaggagct tgaagccatt ggcaattggg
    29461 ctgttcagca tgatattctg atcctggcag atgatatcta tggtgcattg gtctacaatg
    29521 gcaatcaatt tactccaata tcagccttat cagaggctat tcgtagacag accattactg
    29581 taaatggcgt tgccaagagc tatgcgatga caggctggcg tttgggcttt gcggtcggag
    29641 acactgatat tatcgctgct atgggtaaga ttatcgggca aaccacctct aatgtgacaa
    29701 cagcgtccca atatgcagcg attgaggcct ttggcggtga ccaaacgtca gttgaggaga
    29761 tgagacaggc ctttgaagag cgcctcaata ccatttatcc cctgctcaat caagttcctg
    29821 gctttgaggc tattaagccc caaggagcct tttatttctt tcccaatgtc aaaaaagcta
    29881 tggagatgaa gggctttacc gatgtgacag cctttactga tgcgatccta gaagaggtag
    29941 gactggctgt tgtcagcgga gctggctttg gtgctccaga aaatatcagg ctaagctatg
    30001 ccactgattt ggcaacccta aaagaagcta tcagacgact caatcagttc atgacaactg
    30061 acagcagcca tgacaacaaa gagaatgaat agaaaagaga cattatgacc aaaaaatacg
    30121 tttccattat tgatgttaaa gaccatgtag gacaagaagt gacagttggt gcttgggtcg
    30181 ccaacaagtc aggcaaaggg aaaatagcct ttttgcaatt gcgtgatggc tcagcctttt
    30241 tccaggcagt tgcctttaag ccaaacctga tccaagcctt tggtgaggaa gcaggagcag
    30301 ctaagtttga cacgattagg catctcagcc aagaaacctc tgtcttagta aagggcattg
    30361 tcaaagagga cgctagatca aaatttggct atgagctaga cattacggac ctagaggtta
    30421 ttggggattc caaggattat ccaattactc caaaggagca tgggacagac tttctcatgg
    30481 atcaccgtca cctttggctg cgctctcgca ggcaggcagc aatcatgcaa atccgtaatg
    30541 ccatcatcta tgcttcctat gagttttttg atcaaaatgg ctttatcaag tttgatagcc
    30601 cgattttatc aggcaatgct gctgaaaaca caacagagct atttgagaca gattattttg
    30661 gcaatccagc ctttctcagc caatcaggtc agctatacct tgaggctggt atgatggcgc
    30721 ttggtcgcgt ctttgacttt ggtccagtat ttcgtgccga aaaatcaaaa acgcgccgcc
    30781 atctgacaga gttttggatg atggacgcag aatacccttt cttatcccat gaggaatcct
    30841 tagacctaca ggaagcctat gttaaggcga tgattcaggg cgtgcttgat cgtgccccac
    30901 aggcattgga gcttttagag cgtgacacag agctgctgaa aaaatacatt gcagagccct
    30961 tcaagcgtgt ctcttatgat gatgcgatca gcctgctaca ggagcatagc acagatgacg
    31021 atgccgacta cgagccaatt cagcatggcg atgactttgg ctcaccgcat gaaacctgga
    31081 tttccaatta ttttggggtc ccaacctttg tcatcaacta cccagctagc tttaaggcct
    31141 tttacatgaa gccggttccc ggcaatgaag aacgcgtgct atgtgcggac ctgctagcac
    31201 cagagggcta cggtgagatt attggaggct ctgttcgtga ggataactat gacaaattgt
    31261 tggcgaaaat caaggctgaa ggcttaaatc ctgaggatta tgacttttac cttgaccttc
    31321 gcaaatatgg ttcagtgccg catgctggct ttggccttgg actagagcgc atggtgacct
    31381 ttgtcgccgg caccaagcac attcgtgaag ctattccatt cccacgcatg cttcatcgtt
    31441 taaaacccta atgaacccta tcagcgtcca atcttgggcg cttttttgtt ggactgagaa
    31501 gcacacttag tacctaagtc ttacagctag tcttggtaga gctgtggagc tttgcagagc
    31561 tattgtaggc ataggcagtg ctgtatttaa caaggttaaa atcagataat taatattaaa
    31621 attaaaaaaa aaaaaaacaa aaccaaggag gatcggtgag cttattagtt tggcactaat
    31681 catcatcatg ctataattgt cttcacaaat aatttagaaa tagatcatat ttctatcatt
    31741 aaaggagaga gatgatgaat cgtaaaaagc ataccaaact cattcgtaac tacagtatct
    31801 gctcagcagt ggctgtccta gcagcagtta gcttggggac aggtcagcaa gtacaggctt
    31861 cggattccgt tcgatttccg aatgtgagag attacattca ggaagagtat aatggagatg
    31921 ttgaaaaatt atctcgaagt ctgcaaattt attttggtaa tctaaaagag tacatagagt
    31981 tccaatttga gaatcgaaat caaggtcctg ctggcccagc cggtccaaga ggtgagcgtg
    32041 gtccgcaagg tgagacaggt cctgctggtc ctgccggccc tcaaggccca cgtggagaaa
    32101 caggccctgc tggtcccgca ggacaacaag gacaaccagg agaagctggt cccgccggtc
    32161 ctcaaggccc agcaggacaa cctggtgttc aaggacctaa aggagataaa ggtgacaagg
    32221 gtgatactgg cgcaacaggc cctcaaggcc ctgctggtcc aaagggtgaa cgcggtgagc
    32281 aaggaccaaa gggtgaacgc ggtgagcaag ggccaaaagg cgaccgtggc gaacaaggac
    32341 caaagggtga acgcggtgag caaggaccaa aaggtgatcg tggcgaacaa ggaccaaagg
    32401 gtgatcgtgg cgagcaagga ccaaaaggtg atcgtggcga acaaggacca aagggtgatc
    32461 gtggcgagca aggaccaaaa ggtgaacgcg gtgagcaagg accaaaaggc gatcgtggcg
    32521 agcaaggtcc aaagaaggag ccagaaaaag acaccaagcc atcagtgcca aaggcaccag
    32581 ataatatggc tgcaccaaag gctccggaga agaagaaccc taaagcaccg gctcctaagt
    32641 cagctccaaa ggcatcattg ccatcaacag gagacactag ccaatcattt gttgcagcag
    32701 cccttggcct tatcgctagc gcgggcttgc tagtcttcaa aagaaagaaa aattaagcta
    32761 gctaaagact gtaaacaagt ctcaactgtt acagcaagcc tctttgacat cttgcagata
    32821 aagagaacct cttagcgaat aaagtgaacc taaagtcaga gcttctgctg tgctagcagt
    32881 agcttatctc cctgaaacaa tcagtcatgc taaagcattg agccttagtt gcaaggctta
    32941 ggtgtgacct ttcaaaggaa gctgcttttg cctgtatcac tttaggaaga tatctaaaag
    33001 agacgcttgt ttcacactga agctaagcta gcttttccta tgacaactat cctataataa
    33061 taaactccaa acaaaagaga ggtcaaatga gatctctctt ttgcttagct ttaggatgga
    33121 taggcttaaa ggcagctctg tttcttgatt aagaagtcct tgctgataga gtctgtctta
    33181 gccgggctta tatggtataa tacctaatgg agataagaaa agcccttaag aaatagagtt
    33241 tcatctattg ttacaggagt gatcaagtga aaggagatgc taaatgtcag ataaacaaat
    33301 caatttggtt attgttacag gaatgagtgg tgccggcaaa acagttgcca ttcaatcatt
    33361 tgaggatttg gggtatttta ctgttgacaa catgccacca gctttagtgc ctaagttttt
    33421 agagctgctt gagaggacca atgaaaccca aaaggttgct ctggtggtgg atatgcgcag
    33481 cagacgcttt ttcaaggaga ttaattcgat cttagatcat attgagctaa attccaacct
    33541 caagctacgg atcctctttc ttgacgcgac tgatagtgag ctagtatcac gctataagga
    33601 aacaagaaga agtcaccctc tggctgctga tggtcgggtg cttgacggca ttaggcgaga
    33661 aagagagctg ttagtgccgc ttaagagcat gagtcagcat gtggtcaata ccaccgatct
    33721 aaccccaaga cagctgcgta aggtgatttc ggatcagttt tcaagcgagt cagaccaagc
    33781 ctcatttaga attgaggtga tgagctttgg ctttaaatat ggcctcccct tagatgcgga
    33841 ccttgtcttt gatgtgcgct ttttgcctaa tccttattat caggtggcgc taagagagca
    33901 gacagggctt gatcaggctg tttttgatta tgtgatgact catcaagagt cagaggcctt
    33961 ttataatcat ttgttaggct tgatcgttcc tattttgcct gcttatcaaa aggaaggcaa
    34021 atcagtgcta accattgcta ttggctgtac aggtggtcag catagaagcg tcgcctttgc
    34081 ccatcgcttg gcccaagact tgacagcaga ttggccgctg catgagagtc atcgggacat
    34141 caatcgtcgt aaggaaacgg taaatcgctc atgagaaatc ctaaaataac ggtgatagga
    34201 ggaggaacag gcattcctgt tatcctaaaa agccttcgca aggaggcagt tgacattact
    34261 gcggtggtca ctgttgctga tgatggcgga tcatctggta agctgcgcaa tgccatgcag
    34321 cttaccccac caggtgattt gcgcaacgtc ttgttggcca tgagtgacat gcctaagttt
    34381 tatgagcgtg tgtttcaata tcgttttaat gaggcagatg gtgctctagc tggtcatcct
    34441 ctaggcaatt taattatcgc aggtatttct gagatgcagg gatccaccta taacgctatt
    34501 cagattttga cgaaattttt ccatatcact ggcaagattt ttccctcaag cgagcagcct
    34561 ttgacactgc atgctgtctt taaggacggt catgaggtgt caggagaaag ctctattgcc
    34621 agctaccagg gcatgattga ccatgtctat gtgaccaata cctacaatga tgacttgcca
    34681 aaggccagtc gcaaggtggt tgaggccatt ctccaaagtg atatgattgt gcttggtcct
    34741 ggttccttgt ttacctctat tttgcccaat cttgtaattc cagagatcaa agaagccctg
    34801 agagtaacaa aggcagaggt ggtttatatt tgtaacatta tgacccagta cggtgagaca
    34861 gagcaatttt ccgatgcgga tcatgttgcg gttttaaatc agcatctggg cagggactta
    34921 attgacactg ttttggttaa tgttgagcag gtgccaaaaa gctatatgaa ttccaaccaa
    34981 tttgacgaat atctggtcca agtagagcat gactttgcag gtctgtgtaa gaccgcaaag
    35041 cgtatcatct cgtctaattt tctgcgtttg gagaatggcg gagcctttca tgacgggcac
    35101 ttggttgtag aagaattaat gaacctagtt aggataacca agctatgagt tttacgacaa
    35161 cagttaaaga ggaattgatt catttatctg cttctgatca aacggaatta tcagcaatca
    35221 tcaagctggc tggtagctta ggcttggcta atcagagcct gaatttgtct atcacgactg
    35281 aaaacgctaa gattgctcgc tacatctatg cgcttatcga agatacctat catatcattc
    35341 cagaaatcaa gtaccatcaa aaaaccaatt tgaaaaaaaa tcgtgtctat acggtttatt
    35401 tggataagca ggtggataag ctcttagcag atttaaagct ggcagattct ttttttggca
    35461 ttgaaacagg tattgagcag caggtcatgt cagatgatga tgctggtcgg gcctatctca
    35521 agggtgcttt tttagcggca gggactgtaa gggatccaga atccggcaag tatcagctag
    35581 agatctactc tgtctatcta gaccatgctc aggatttggc ccagctcatg cacaaattca
    35641 tgctagatgc caaggttatc gagagaaaaa atggtgcagt aacctatttg caaaaggctg
    35701 aggacatcat ggattttctc attattattg gtgccatgtc gtgtaaggag gagtttgagg
    35761 ctgttaagct tttgcgtgag gcgagaaatg acatcaatcg ggccaataat gcagagactg
    35821 ctaatattgc taaaaccatc accgccagca tgagaactat caataatatt atcaaaatca
    35881 tggatacgat tggcttggac agcctgccag ttgagctgca gcagattgcc cagatgagag
    35941 tagccaaccc agactattct cttcaacaaa tcgcagattc gcttgacttt gccatcacta
    36001 agagcggggt caaccatcgc ctgcgaaaaa tcaataaact ggcagaggat ttataaagac
    36061 agcttagcct ttttcaggct gataaaaaag ggggtaaggt gatacgaaca agccgccttt
    36121 taaggcatgc cttgttgagc tttctctagg ctgttgatgg agtgccctct aaggactgtt
    36181 gttattgtta ccacaatggg ctatctggtt tcgagactac ttggctgatt agtaagcttt
    36241 tctaatggct ggctctgccc aagattagtg acatagctgt taaggcttat cgtgattcaa
    36301 caagagacct tggcctcttt tttgcttgtc ggaattattt ttttaggctt ttcttacaaa
    36361 tgagaggata atgtgacaat ctgtggtatg atattagtaa tgaatgcaaa ggagaacaaa
    36421 tcatgtcatg cacaactatt cttgtcggta aaaaagcaac ctatgacgga tcaacaatcg
    36481 ttgctcgtac agaggattca caaaatgggg aatttacccc taaaaaaatg acagttgtta
    36541 gaccaaaaga ccaacctaga cactatcaat ctgtcttgtc tagctttagc atggagctgc
    36601 ctgatcagcc gatggcttat acctcggtgc ctgatgccct aggaaaggac ggtatctggg
    36661 gagaagcagg tgtcaatacc ctcaatgtcg ctatgtcagc aactgagacc attacctcaa
    36721 atgcccgcgt tcttggagca gaccctcttg tttcctctgg tattggagaa gaggacatgc
    36781 tgaccttggt gcttccttat attcgttctg caagagaggg tgtgtttcgt ctgggagcga
    36841 tcttagaagc atacggtacc tatgaggcta acggtgttgc cttttctgat gagcatgaga
    36901 tttggtggct ggagacagtg ggtggccatc attggattgc aaggcgcgtt cctgatgatg
    36961 cttatgtcac taatcccaat cagtttggca ttgatcactt tgaatttaac aatccagagg
    37021 aatacctgtg ctccaaggat ttaaaggact ttattgccaa ataccatctg gatttgacct
    37081 atagcaacga gcatttcaac cctcgctacg cctttggtag ccaaagagat aaggatcgcc
    37141 attacaatac accacgcgct tggattatgc agcaatactt taatccggag tttctgcagg
    37201 atccgcgcag ctttgagctt ccttggtgcc aaagacctga tcgcaaggtg accattgaag
    37261 acgttaagta cgtgcttagc aatcattatc aggacacccc ttatgatcct tatggcccag
    37321 aggggacgcc gactagtcga aaatccttta ggccgattgg tattaaccgt acgagtcaaa
    37381 ctgctatttt acatatccgt cccaacaagc ctaaggaaat tgctgccatt cagtggatgg
    37441 cctatggttc gatgcccttt aatacaatcg ttccgctatt cacccaggtc aagaccattc
    37501 cggattattt tgcaaacact gttgaaaatg tttccacaga taatttctac tggaccaatc
    37561 gcttgattgc agccctggct gatcctcact tcaagcacca tgaaacagat ttggaggact
    37621 acctcgaaaa aacaatggcc aagggtcatg ccatgctaca tgctgttgaa gcagcgctag
    37681 taaaaggtca gccggttgac ctagaagagg ccaaccaagg catgagtgat gacattcagg
    37741 cagatacaca ggctctgctc aataagatcc tctttgatgc cagcaatctc atgaccaacc
    37801 gctttagcct aagcgactaa gtaatctcaa tagtcaaacg agctcatatc attatagata
    37861 tgggctctca gcttaaaaag gatagtagag cagccttacc gccaggctaa tggtaatgat
    37921 gagtccagtt agggtaaaaa aggagcactc agctaatgca aaaaaagtaa aaaacttgca
    37981 aaagaatgat attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata
    38041 tatagaggag gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt
    38101 tttgcgggac agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt
    38161 accaccttct atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg
    38221 tctatgctga tgaaggcagg aacagagcct catgattttg agccgtcaac aaaggacatc
    38281 aaaaagatcc aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtt
    38341 cctgatatga agaaatcact gacttctaag aaggttgcgg tgattaaggg aacaggagac
    38401 atgctgctgg tagctggttc tggtcacagc cacgagcatg gccatgacga tgccgataaa
    38461 aagcatgatc atgaccacga cgaggaaggg cacagccatg cttttgaccc acacgtgtgg
    38521 ttgtcacctt atcgcagcat caccgttgtc gaaacaattc gtgatggtct gtctaaggct
    38581 tatcctgaca aggctgacca cttcaagtct aatgccgctg cttatattga aaagctcaag
    38641 gaattagata aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact
    38701 cagcacgcag cctttggcta tatggcgctt gattatggct tgaaccaaat ctcaatcaac
    38761 ggtgtcacac cagatacgga gccttcagca aagcgcattg cagagctatc aaaatacgtc
    38821 aaaaaatatg acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa
    38881 accctagcca aggaggctgg tgtcaaaaca gctgttctta gcccacttga aggcttaaca
    38941 gaaaaggaca tgaaggccgg caaggattac tttactgtta tgcgtgaaaa cctcaaaacc
    39001 ctacgcttaa caactgatgt agaaggaaaa gaaattcttc cagaagaaga cacgactaag
    39061 actgtttaca atggctactt caaggataag caggtcaaag accgcaaatt gtctgattgg
    39121 tctggtagct ggcagtctgt atacccattc cttcaagacg gtacattaga tcaagtctgg
    39181 gattataagg ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac
    39241 accactggct atcagacaga tgtcagccat atcaagatta atggtaagaa aaacaccatg
    39301 acctttgttc gtaacggtga aaagaaaacc tttacttata agtacgctgg taaaaagatt
    39361 ctaacctatc caaagggcaa tcgtggtgtg cgcttcatgt ttgaagctaa ggagccagac
    39421 gctggtgaat ttaagtatgt tcagttcagt gaccatgcca tcgcaccagg taaggcggag
    39481 catttccacc tatattgggg tggtgacagc caagaaaagc ttcacaagga gctagagcac
    39541 tggccaactt actatgatgc agacctatca ggtcgtgccg ttgcccaaga aatcaatgct
    39601 cattaatcac tcaaaagact aggcagttta atcggcctag tcttttcttg ttttagtgac
    39661 tttcagtccg tctcgctccg aaggtgcgag acaaataaac cacccgtttg acgagtggct
    39721 atgattttag tgctgtataa gacttaaatg atgaaaggtg gtctcaaaac tttattttta
    39781 atttttctga ccatattttg gttgtgttta tttattaata ccaaatccat tgttttaggg
    39841 attgtatagc attaatatgt gaaatatttt aatattttac caaaaaagta ttgactttca
    39901 gaccatatta taatattatt tgagtggtta taacaagtta ggggtattag tatgataaag
    39961 gagcagccac tctacttaca aattgttgat gtattagagg tcaaaattag aaataccatg
    40021 tcagctaatg ataaattgtt gtccgaacga gagctaagtg acttatttgg tgttagtcgg
    40081 ataactatca gattggcact taaggagcta gaactgcgtg ggcttattta caaacagcag
    40141 ggcaagggga cctatgtatc tggcataaag gagcctgcta cagacctgtc ctcagcctat
    40201 agctttaccg aggagatgaa aaagcaaggt cgtaagcctc aaacagtcat tctttcattt
    40261 gaaaagatca agaccacagc ttacttgtct ggtatgttag atttagatgt tgatactgat
    40321 gtttttgagc tagagcgtct aaggattgca gatggaaagc cattaatgtt tgagcgtact
    40381 tatatacctg aaaggggatt tgaggggcta accagtgatt tattggaaaa aaagccctta
    40441 tatgatgtgt ttgctgagga ttttcaggaa gctatccgat tagctgatga ggagttttat
    40501 gctagtatcg ccctagatta tgaagcaagg ctattaggga tcaaaaaggg agatcctgtg
    40561 ctgcatatta tgcgcaagac ctataatgag aaaaataggc taatcgaatt tacctttagc
    40621 attgctagag cagaccagtt taggtaccgt atccagcacc accctagcaa gaagatatag
    40681 gaggcaagag aatgtttaca aaaacacaag cagaattaga gctacttggc gcagctatca
    40741 ccactagaga aatcaagcag cagccagagc tatggttaga ggtctttgag tcctttctta
    40801 agcaaaaaga aagtctttta gccttttttg ataggattcg tgaaagcgct aacggcgata
    40861 aggtaaaaat tatttttaca ggagctggaa cctctgaata tattggcaat accatttgtc
    40921 attatttgga gatgactggt gatagggaaa attatttatt ttacagtatt gcttccacag
    40981 accttgttgc agctccaagt cagtatctct ttgaagagga cacagtcgtg cttgtttcct
    41041 ttgcaagaag tggcaatagt cctgaaagtg ttgctgctgt cagtcttgtt aatcagctgg
    41101 tgtcaaatcc ttatcatttg gtgataacct gtgccaaaga gggggcctta gctcaaaatg
    41161 ctaagaagga ccaaaggagc tatttgttct tgatgcctga ggcctcaaat gatgctggct
    41221 ttgctatgac gggaagcttt agctgcatga tgctagcggc cttgttgatt tttgatcaag
    41281 cgcactccct tgaaacgaaa aaatgctatt tagatcagat tgtagctatg gtagcagcta
    41341 ttattcagca ggaggctgat ttacaaaaac tggctagctt agcatttcag cgtttggttt
    41401 atttgggctc aggtgtccta gcaggtctta cgcaagaggc tcaattgaag attttagagt
    41461 taacagccgg taggattgca acggtttatg actcctctat gggctttaga catggtccaa
    41521 agtcatttat tgatgatcag acattggtta ttggttttgt tagcaatgat ccttatacga
    41581 gaaggtatga ccttgatgtt ttagaagaga taagagagga tgctattgct gttgatacgg
    41641 ttgcattaca gcagcaagga ggtgagggct ttagtgggca ttgctttgac ttagactcgt
    41701 caatgctttt gccagatgct tatttggcct ttccgcttgt ttttatcgct caaacaattg
    41761 ctttgctgtc gtctattaag gttaataatt taccagatac cccttcggcc acaggaacgg
    41821 ttaacagggt tgtccaaggt gttaagattt atcactattt taagtaggag aacaagatgt
    41881 accatttatc aaaagctaag tatcgtcttc ttgaaaaggt cagtcgtaag ggaatcattt
    41941 cggccttggc ctttgatcaa cgcggtgcct tgaagcgcat gatggcagcc caccaagaca
    42001 cagagcctgc cccttggcaa atcgaatccc taaaggctct ggtatcagag gagctaaccc
    42061 cctatgcctc ctctatcctg ctagaccctg aatatggcct accagccacc aaggtgcgtg
    42121 atgagaagtc tggcttatta ttagcctatg aacaaaccgg ctatgatacg acaaccacca
    42181 gccgcctgcc agattgtctg gtggattggt cagtcaagcg cttcaaggag gctggggctg
    42241 acgcagtgaa gttcttgctt tactatgatg ttgatggaga tgaatacatt aaccagcaaa
    42301 agcaggccta tattgagcgt atcggctcag aatgtcaggc agaggagata ccatttttcc
    42361 ttgagctatt gacctatgat gaggcgataa cagacaatca gagtgtagcc tttgccaagc
    42421 taaaggcaca taaggttaat gaggccatga aggtcttttc agctaagcgc tttggggttg
    42481 atgtcctaaa ggtagaggtt cctgtcaata tggcctatgt tgagggcttt gcagagggtg
    42541 aggttgttta cagcaaagag gaggctatgc aggcctttcg tgatcaagag tctgctagtc
    42601 atttgccata tatttatttg agtgcggggg tatcagctag tctgtttcaa gagaccttgg
    42661 tttttgcggc agaggcagga gctaggttta atggagtgct atgtggtcgg gctacctggt
    42721 caggagcagt agcggtgtac atgtcagagg gcgaggcggc agcgcgtcaa tggcttcgca
    42781 cagagggctt tcagaatatt gatcgcctaa accaggtgct tgagaaaaca gccagccctt
    42841 ggacaacaaa gcttactgtt gatgaagcct agtaaaggca tgataaaagc aatgctagga
    42901 cattgcttct gcattattgg taatcactgg aggacaaggc gtacttgaaa aattgccaat
    42961 gcttgtaaga ctcggtgtac tctaggatac ggccattatc tgtcgaccga gtgagcttgg
    43021 tttgaaggac acaaggagtg ttgtctatca tgtttaaaaa tgtagcgaca tctttaggca
    43081 tgtgatccgt cagctgtgtt tgctgggtga agctttgtga ccgcatttga atgtgataat
    43141 ccaaaaagaa gcgcttataa agcgactggt agtcagctaa atcacgctca gggcacagca
    43201 ggtaatcatg aggaatataa gatagttggt ataaataggg ctgctgatta atcgttcgtg
    43261 tacgggagat ggtgtagtaa aattccgttt tatgaagttt caagagattt agatagtagg
    43321 gatcatttcc cttaaccaca ctaaggacag tcacctcctc tttttgatcc ttaaaggtat
    43381 ctagatagga aaattggact agctgttctt ttctggtacg ggtaatgaag gttccaagtc
    43441 cctgccttct tctgataaag ccctcttttt ctaattcctt cagggctcga atgatggtta
    43501 tggagctaac atgaaagcgt ttaattagct cggcttcggt ataaaatttg tccccggtat
    43561 ggtagtggcc attcagaatt tggttttgta attcttcttt gattagtcgg tattttgggt
    43621 atttgatgtt catagttact cactcaataa ttgtttaata cgattatagc aaaaatagca
    43681 agctgatgtc atatcttacc agttattgct cagatagctt gtcaatcagc cattgatcaa
    43741 aggctgatgg ttaatgaata aaaggagata atatgaagca attttgcata aaggagcagt
    43801 tttaccttga tggcaagccg tttaagatat tatcaggtgc cattcattac tttaggatag
    43861 ctcctgatag ctggtctagg gtgctttatc agctgaaggc cttaggcttt aatacagtag
    43921 aaacctatat tccttggaat atgcatgagc caaggaaggg acagtttacc tttgagggga
    43981 ttgcagatgt tgaggcattt ttggatttgg cacaggaatg tggcctatat gctattgtca
    44041 gaccctctcc ttatatctgt gctgaatggg agtttggtgg tttaccggct tggctattaa
    44101 ctgaaaattg taggctcaga tcaagcgatg aggtctttct taagcatgta tcagattatt
    44161 atgatgtgtt actaccaaag ctggtgaagc gtcagttaga taatggcggc aatattctga
    44221 tgtttcagct tgaaaatgag tatggttctt atggtgaaga aaaggcttat ttaagaaaat
    44281 taaaagagct tatgcttgct aaaggcatta gtgcccctct ctttacctca gatgggcctt
    44341 ggccagccac gctagcatca gggagtctga ttgacgataa tgtttttgtg acaggcaact
    44401 ttgggtcaaa tgcttcaaag caatttgcca gcatgcagga ttttttccaa gcatatcaaa
    44461 agcaatggcc tctgatgtgt atggaattct ggttgggctg gtttaatcgc tggaatgagc
    44521 caatcattcg aagggacccc aaggaagctg ttgatgcaat catggaagct atagagctag
    44581 gcagcattaa cctttatatg ttttgtggtg gcactaattt tggctttatg aatggctcgt
    44641 cagctcgtct gcaaaaggat ttaccacaga taacctccta tgattacgac gcattactag
    44701 atgaggcagg aaacccaaca aagaaatata ccctgctgca agaacgtctc aaggagcgtt
    44761 acccccaatt atcctttgca gagccaatga tcagttctac gatggcctta gagtctatca
    44821 agctgtcagc aaaggttagt ctttttaaga caatcaaaaa tgttagcgct atcaagaaaa
    44881 gtttttatcc ttgtaatatg gaggagctag gtcagccaac gggctaccta ctgtatagga
    44941 cgcacctcgc tagacatagc aaggaggagc ggctcagggt cattgatgct agagaccgca
    45001 ttcagctctt tttagatgaa aagcacgtga aaacccagta tcaggaggaa atcggtcagg
    45061 atatactgat acatcaagag ggtgagacca cacagcttga tattttagtc gaaaatatgg
    45121 gacgtgtcag ctatgggtac aagctgacag caccaagcca acaaaaagga ttaggcagag
    45181 gcttaatggc tgacttgcat tttgtaggtg attgggagca ttttccgcta gattttcaag
    45241 agctggattg gattgatttt tctgcaggtt ggaccgatgg ggtgccagga ttttatgcct
    45301 atgattttga ttgtcagcag ccggcagata cctaccttga tttgagtcaa ttcggaaaag
    45361 gagttgctct tgtgaatggt gttaacctag ggcgtttttg gaaggttggt ccaacattgt
    45421 cgctttatat tcctaaaggg ctattaaagc aaggtcaaaa tagactgctg atatttgaaa
    45481 cagaagggca gtttagtgag tcaattcgtt taactaagga accaatttat aatgatataa
    45541 aaggagaaaa cttatgacaa ttgttgcagc acgtattgac ggccggttaa ttcatggtca
    45601 ggtagctaat ctatggacga caaagctaaa cattagccgt atcatggttg tcgataatga
    45661 ggtgattagc aatgaccttg aaaaaacagc actgaagcta gccacaccta gtggtgttaa
    45721 gttatctatc ttatccgttg aaaaagcagc caacaatatt ttggaggggc gctatgattc
    45781 tcaacgcttg ttgatagtag ccagaaagcc ggatagcttt ttagggctaa ttcaaaaagg
    45841 ggttactatt tcagagttaa atgtcggcaa tatgtcacag acgccagaga ctcgtccggt
    45901 aacgcgttcc attaatgttg tagatgagga tatagaggca ttcaaggcta tttcagccaa
    45961 ggggtgtcat ctcattgccc aaatggtgcc taatgatgcc ccagcagact ttatgccgct
    46021 gttggataag gttgattaag atgtgtcaaa tcaaaaacga atctgtttca ggaggtaaaa
    46081 gcgtatgatt caatggtggc aaatcctatt attaacactc tactcagctt atcaaatatt
    46141 agatgagcta acaattgtct cttctgcagg ctcacctgta tttgcaggat ttatttcagg
    46201 tatcattatg ggagatgtgc aaaccggtct ttggattggt ggtagccttc aattgatggt
    46261 gcttggtgtt gggacctttg gaggagcttc gcgtatcgat gcaacctctg gtgcggttat
    46321 tgcgacagcc ttctcggttg ctcaaggcat agagccagaa ttagcgattt caaccattgc
    46381 agttccggta gcggccttgc tggtttatac tgatattcta ggacgctttt caacgacctt
    46441 ctttgctcac cgtattgacc gccatgttga aaactttaac taccgaggca tcgagcgtga
    46501 ttaccttatg ggagctgtac cttgggccct atcacgtgct ctgccggtat ttttagcggt
    46561 ctctttaggt ggtggtgcgg ttgatacagt tgttaagttc attgaccatt atgaatggct
    46621 agcaaatggt ctaactcttg caggaaaaat gcttccaggc ttgggctttg cgatcttgct
    46681 tcactaccta ccagttaaac gtaatctcca ttatctggct ttaggttttg gcttgacagc
    46741 aatgctaaca accatttata ccaaccttca ggtagctgga ggcgcccttg caggagtagc
    46801 caaggatttc aatgccgcac cattcaaggg gctgccaatg attggtattg ctattattgg
    46861 acttgccttg gcaaccctcc attataaaaa tggtcaacaa gcacctgtag ctgaacaaaa
    46921 acctggggta tcagaaagtg gggaaattga agatgacgaa atctaattat aaattaacca
    46981 aacaggattt taatcaaatc aataagcgca gcctgttcac attccaatgg ggctggaact
    47041 acgagcgtat gcagggctct agctatcttt acatgatttt gccacagctt cgtaagattt
    47101 atggcgatgg aactccagag ctaaaagaaa tgatgaagac gcacacgcag ttttttaaca
    47161 catcaaattt ctttcatacc attatcacag gaattgactt ggcgttggag gaaaatgaag
    47221 gccttgcctc aaaagatgct gttaatggga tcaaaacagg cttaatgggg ccatttgctc
    47281 caattggtga ttcggtcttt ggctccttag taccagctat tatgggctct atagccgcag
    47341 gtcttgctaa agaaggggtt tggtcaggga ttactggcgt attgatgtgg gtatgtactc
    47401 agatgatcat caatgtgttt cgttggaagc agcttgagat tgcttataaa gaaggtacaa
    47461 agctcgtcac caccatgcgt gataagctaa ccgctgtagt agatgcagcc tcagtcatgg
    47521 gagtattcat ggtaggggcc ttaattgcaa cgatgattaa ttttcagttt accgcagcac
    47581 ccaaaattgg tgagaaggtt atcaatattc aagatttaat tgataccatt tttccacgtc
    47641 tagttccagc cttatttacc ggagccatct tctggctgct agggcgtaag ggcatgtcct
    47701 caactaaagc aattgttgtg attattttat ttgccttagt gatgtcttat ttcaatattt
    47761 taggagtata gctgatggca caaactttaa ttctcattag tcatggagcc ttttgtcgag
    47821 agctaaaaaa gagtacagaa atgattatgg ggccacagga caatatttta acagcagagc
    47881 tgcaaccaaa cgaaggtgcc gatgacttta aagaaaagct tttaaggcta attgcaggct
    47941 tagatgatgt tcttgtattt gcagatttga tgggtggaac accctgtaac gttgccagtc
    48001 gtttattaat ggaagggcat caatttgagc tgtatgcagg catgaatatg ccaatggtta
    48061 ttggcttcat taatgcttgt ttgatcggtg aacagcttga tttcaaagcc tttgcctgtg
    48121 acaatattca ccatgtcaat accctcatct cagccctagc agatgatgat gatgactaac
    48181 caagctcgtt tatttgtttc gcacctatcg gagtgaaacg gactgaaagt tgcataagca
    48241 aaaaagacac tgcctgaatt tggcagtgtc tttgctgtaa gcttattatt ttgctgcatt
    48301 cgcgtctttg agaccgtatt ttttgttgaa acgatccaca cgtccatcgg cttgcgtaaa
    48361 cttttgacga cctgtgtaga atggatgtga gtctgatgaa atttctacac gaacaagagg
    48421 ataagtttcc ccttcaaact caatggtttc tttagaggtc ttagttgaac cgctaaggaa
    48481 tttgtagcct gtagttgtat caaggaaaac aactggacga taatctggat gaatgtcttt
    48541 tctcatctta aaaaagttcc tttctgccat gatactgtcc gtatcatagt tattaactat
    48601 tctagtttaa caaaagttag taagcttgac aagctttttc tatcactatt catcaataag
    48661 atgataagtc ttatgttaag agatcaatca gctcttggta gatttgctca ttttcctcta
    48721 agcctgatga cgtggcaccg ctagcaagag ggtgcccgcc tccttgatga cgcttagcaa
    48781 taccattgat gaccttttct ttactgcgca tgcgtactcg gtactggcca tctggcagct
    48841 caacaaagat aacccaagcc tgcaccacgt ctatttttcc aggagcagag acaattgctg
    48901 agctttctgc caagctaata ccaaaggagt ttagaacctt ctggctaagc agtaggcggg
    48961 ctgcaccact ggcatctata tcaagctgct caaaaacata accttgtagc ttggcaattt
    49021 taagtggaaa ggaatccatc tgtctagaaa tggcagcaaa gtcaaaggta tagtttctta
    49081 attggcttgc aatggctagt gttttgctgc ttgttgaggc atagagaaag cgtcctgtat
    49141 ctcccacaat gccagtatat aatagtctgg ctgcctcatc agtcaaggcc aagccttggc
    49201 taaaggcaaa ttcggcaata atctcactag cacttgaggc cttggtgtca acgtaggaga
    49261 gatcaccata gatatcatcg ttagggtgat gatcaatttt aatgaggcaa gcgcccattg
    49321 tgtagcgctc atcatcaatg cgggggcgat tggcagtgtc tgtaacaatc actaaagctt
    49381 ccttataatc atcgtcggac acctgatcca tgagactaat ccaagccaga ctaggctcat
    49441 caaagcctgt tatcaggacc tttttgtcag ggaaattatg cctgataatc tctttaagtc
    49501 ctgcttggct ccctagagca tctggatcgg ggttttggtg ccgatgaatg atgatggttt
    49561 gatagtgctt aatgtgttct aaaatagttt gaaacgttgt cataggtatc ctttaatttt
    49621 tgatcatatc aatgtgagga atattgtctt ccagataaat ctcagagact gctttaaacc
    49681 caaatgagct gtaaaaaggc tcaagatagg cttgcgcttg agcgtagatg ggaatttttg
    49741 gaaagtgctg ttgacaatag gctaaggcct gatgaactaa gtcacgccct agtcctgccc
    49801 gccttgcctt ttgtgctacc agtactcgtc ccagctttat gctattgtca gttgggatta
    49861 agcgacaata ggccctaagc tctgaatcga cctgcttgaa aagatggata gctttttgat
    49921 ccaaatcgtc aatatcagga tagggacatt gctgctcaac cacaaaaact gccacacgct
    49981 ctttatagat ggcaaacaat tcatctcttg ttaactgatc aaatgcttta acaacccaca
    50041 ttaactagcc tccaaaatca ctggtacaat ttcctttatg ataacataat agcatatatc
    50101 agccataatg gaacgaaaaa aacctgtctc ttaatggatt atgtcgtaat gataattaca
    50161 tcttgtctca aaagctggta atcatcacag gcacagaaaa atgtgcccct tctgttgctt
    50221 tttgagaaaa agttcacttg ctttttggta gttttttggt atcatactaa aaaatagact
    50281 taattaagga gatacagctt ggaaacaaaa gatttaaaga agcttgctaa agctgagctg
    50341 cactgccatt tagacggttc tttgtcatta gacactattc gtcagttggc ggctttggcg
    50401 caggtagatg ttcctcaaga tgattctgag ttaaagcagc tggtaaccgc accggaaacc
    50461 tgtgaatcct tgatggatta tttaaaaacc tttgatgtta tcagaccatt attacaaacg
    50521 cctcaggctt taacattggc tgcttatgat gttgtgaagc aggctgccct tgaaaatgtc
    50581 atctacattg aaattcgatt tgctcctgag ctatcaatgg atcaggggct gaccgctact
    50641 caggtggtag aggcagtcct aaaagggctt gagcaaggac aaaaagagtt tggcattgtc
    50701 gctaaggcta ttgtgtgtgg catgcgtcag tcctcactag acattagcag agagattttt
    50761 gcaaatgtct tagagtgggc caacaaaggc ttggtaggct ttgattttgc aggcaacgag
    50821 ctggactttc ctccagctgt cttagcagat ttgatcaaag agacgcaggc ctatgggtta
    50881 ccatttacgc ttcacgctgg tgagtgtggc tgtccaaact atattgttga tgctattgat
    50941 ttaggtatca aacgcttagg gcatgtgacg gccattcata accaaaagga tttattggcc
    51001 aagtttatcg ccaatgatgt gacagcagag ctgtgcttca cgagtaatct acaaaccaag
    51061 gctgctagga ctgttgagga ctttccttat atgcagctaa ggcaggctgg cgctaaatta
    51121 tccattaaca cagacaatcg gacagtatca ggtactaacc tgacaaagga atacgaactg
    51181 tttgtcaagc attttgagac aagcgtctca gactttttgg aacacaatcg tgatgcaatt
    51241 aaggccagct ttgccagtcc agctgaaaaa gaagctttat tggctcgttt ggacaaggcc
    51301 tatcagtctt acatcaagaa atgatgcttt tcttggcaaa gtatgataaa atatactgac
    51361 atttagttat tttgggagga aattatggca ttagccaaaa tcgtttatgc cagcatgaca
    51421 ggaaatactg aggaaattgc tgatattgtt gctaataagt tgcaagagtt gggacatgat
    51481 gttgaggttg acgagtgtac aacagttgat gcttcagagc ttgaggctgc tgatatggca
    51541 atcgttgcga cctataccta tggtgatggg gacttaccag atgagattgt cgacttttat
    51601 gaggacttgc aggatttgga tttgtcaggc aagatctacg gtgtagtggg ctctggtgat
    51661 accttttatg attatttctg caaatcagtt gatgattttg acgagcagct cgctgccact
    51721 ggtgccacta agggagctga ctcggttaag gttgatttag ctgctgagga agaggatatt
    51781 gctcgcctag aatcctttgc tgagcaaatg tcacaggcat tagaggcata agtaagactt
    51841 ttgacacaga ttggtaaaac ggtcagtgga ggcttgcgtt ttttaccacc aaatgcatga
    51901 aaaactgata ttttctgatc gttttgtcat gaccatgtgc tctttttcaa gaaaagtcat
    51961 ggcattatta gcctgaatgc aaacaattga tagtgtcaaa atgctgacta tatagtaaaa
    52021 aatgcatgtg actagaaagc agtcacatgc attttcgtca tgcgtatgat gtgaggcatt
    52081 ttgggggtta cttgcttact gagctgaaat tcactataat gaaaaggtaa acaaagaaaa
    52141 gaagaaatta ggtgaatgat gggattagag accatacgac aagatattaa tgctgttgat
    52201 cgtcagttga tcgctttgct ggaaaagaga atggccttgg ttgaccaagt agcggcctat
    52261 aagcaggtac atgatgtgcc agtgcttgat caagagcgag aggctgaggt tttaaggagc
    52321 gtgtcacagc agattcggca taaggccttt gagcctgcca ttcttgagct atttaaggcg
    52381 attatggcag tatcaaggcg ttatcaggct gagcaaatag cggttggttc aaatgatgat
    52441 gaagcctatt aaaaacaatc aagacatcag tataggggat aatgtctatt tggcttttgc
    52501 agccctgctc gttggggtgg tggtaggtgt gatagatact gtttttggac aaggcttgtt
    52561 gctcttgtct gctgttcgtg acgctcatct catttacctg ttaccctgct tagctcttgc
    52621 tggacttgtg attgtgttct tatatgaaca gtatggccaa atcactaagc aaggaatggg
    52681 gttagtgttt gatgtggggc atggtgaaaa agcaaaactg ccactggtgt tgattccgtt
    52741 gattatcctc tcaacctggc taacgcattt atgtggaggc agtgctggtc gtgaaggcgt
    52801 agcggttcaa attggagcaa cagtgtcaca ttttttggga cgtcttagcc atcttaagga
    52861 cagatcccag ctgtttttag tcatgggcat ggccgcaggt tttgcaggct tatttcaaac
    52921 gccaatgaca gcggttgttt ttgccttaga ggtcttattg ctgggaaata taagctattt
    52981 agccttgctg ccttctctta tagcagcctt taccgcctct tggacctctc attgcctagg
    53041 cttagaaaaa ttttcagtcc cgatagccaa ggccttgaaa atcaccccga taacttttgg
    53101 gaaattagtg ctactggggc ttatttttgg cttggttggt aacctttttg ccttcttatt
    53161 ggcaagggct aagccatata ttgcagcaag gctgtcaaat ccctattatc gtgtgttgct
    53221 tgttggtagc attttatcgc ttagcctgct gctgtgccat tacgggcgct atagtggcct
    53281 aggcactaac ttaattacag cggcttttag tcaccaaact attactaatt atgattggtt
    53341 attaaagctc ttgtttacca ttattactct ctcggctggc tttcagggtg gtgaggtcac
    53401 gccacttttt gctattggtg cggctttagg aattgtctta gcaccatggc ttggcttgcc
    53461 agctcagctg gctgcagctc ttggctatgc tgcggtcttt ggcagtgcta ccaatacctt
    53521 tttagccccg atatttgttg gattagaagt ttttggtgca acaaacgcag ccgcttattt
    53581 tatcgtgatg gcctttgcct atatggtgag ccgcaggtat tcaatctaca ctaagcaaag
    53641 ggtgaccact agcatcgttt cctagtgcct tgatcagttt tttgggggaa atagctttac
    53701 aagtggggct tattttgtta gaatagactt cgtgtgtaat ggacacacaa aaattacggc
    53761 taatccgcta agactcgcac ttaagattag taagataagg agaataaaca atgaatccat
    53821 taattcaaag cttgacagaa ggtcaacttc gtactgatat ccctagcttc cgtcctggtg
    53881 acactgttcg tgtgcatgca aaggttgtcg aaggatctcg tgaacgtatc cagatctttg
    53941 agggagtagt catttcacgt aaaggtcaag ggatctcaga gatgtatact gttcgtaaga
    54001 tttctagtgg tatcggtgta gaacgtacct tcccaatcca cacaccacgt gttgaaaaga
    54061 ttgaggttgt gcgtcatggt aaggttcgtc gtgctaagct ttactaccta cgtgccttgc
    54121 aaggtaaggc agcgcgtatc aaggaaattc gtcgctaaaa agagcataag agaggttttt
    54181 tcagtacctt atgaaaagac tgctagagca gcagggtctt tgggacaagc ttcttttcgc
    54241 aggtatgtga acctacgctc gattcaagtc atatcaaagg ctcattctat aatagagtgg
    54301 gctttttgat tgtgattatg ctttagtgcc taaataaatg acagcagtct gattaatgaa
    54361 aggcttgctt gactttggaa atgctcaagg cttgcgctac cagatagaag ctgacatcat
    54421 gacatagcag tcaaggggaa gaaggactag attttttggc gaggtgttga tctgtgaccc
    54481 tgatgttgtt gggaatatga gagtaattaa aaatttcgtc ttgcattctg cctttttcta
    54541 ggttacaata gacaggtagc ctgattaatg gagctaaaga cgtagcgatg atttttgaga
    54601 aagaacggct ctagcgtttc tggctgatct aaattgatag ctttgctagg cagtgtccta
    54661 atcaccttgt cagtcctgct agtttaacgg ataaaacaag cgcctcctaa gcgctagctg
    54721 tgggttcgat tcccgcgcgg gacattaaaa acaaagtaaa aagagtctga gaaggtttga
    54781 cctgcacccc aattgttaga ttttttgtct aactcttgaa gtgtgggtca aagactattt
    54841 gtctcaggac tctttttaac tggttcttta ctaggctgct tcgtctaatt cttcagttgc
    54901 taggttgttt ttctcttcta tatgttggtt tgcatcaagc agcattcctg tgcggtaatc
    54961 taatgctgcc aaaggcgata cattatctag aacaactgag gttataccat aatgatcaac
    55021 ggattctttg ttgcctccca atttgatttg gaggagctct ccgttttgat caattccaac
    55081 gtactgtaac actacttgac gaggaactaa ttcatcattc tgataaatag gagttacctt
    55141 ataatctagc caaaagttag ggtgtatggc taaccaattg tctagtctat tttcataata
    55201 aagcattcct aaaggatttt tatcactaaa acctgtatta aggtattttg tcatagtaac
    55261 taaatttttg ggttcatcat ttaggccgct aaactgataa ccgactagat gtccgcgatc
    55321 cattaaccaa gtctttttcc ctctagaatt aatgacttga tagttatgcc agccgggagg
    55381 attaaatcta agcgcttttc ttttgagagt tggttcatct tgatctttga gttgtatgtg
    55441 tgcataggtg gctctttgta aatgatcaag atctcccaga gctatttggt attttccagt
    55501 aaacggtaaa attcctggta tttcggtagc ttttgttccc aatgatattt ccgttgtatc
    55561 tgggaaggtt ctaagttttc ttgcagattg aacagagtta gctgtgaaaa tagtcagaat
    55621 agttaacaaa acaattgtta gacttttcca gttacggcga cgtgatctag acatatcaat
    55681 gccctcctt
//
LOCUS       DARYSY010000006        53476 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYSY010000006 DARYSY010000000
VERSION     DARYSY010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53476
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            252..1592
                     /locus_tag="TVR04_000280"
     CDS             252..1592
                     /locus_tag="TVR04_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1268997.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDINSRT
                     ESPFFLYVTPKNETTRKVGKEGTVVYCFNRDLHWPENWEQGASKRPENLPLYNKLKGT
                     DDEFRKAASKFRTTISNITNSLVAVLSKDYPTVTSVEGLDETSSRKVTQLAIWYFSDS
                     FDKQWFKGNYKLNDKEDQALQHLIDLGEQASREKKEQSHTLDIYLHESSYTQYQNLLG
                     STLIPKVDPQPDPGPKPKPDPEPMPDPQPKPEPKPEPKPEPKPEPMPKPEPKPQPEPK
                     PEPKPQPEPKPEPKPKPEPKPDPEPMPDPQPKPEPKPDPEPKPDPQPKPEPKPKPEPK
                     PEPKPEPMPKPEPKPQPEPKPEPKPEPMPMPKPEPQPEPMPKPEPKPEPQPKPAPQPE
                     VKSQKPTKPSNTTSQSSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(1725..2843)
                     /locus_tag="TVR04_000281"
     CDS             complement(1725..2843)
                     /locus_tag="TVR04_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268998.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEERAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKLALRSIADSQITEWFKAQANYLLENYNIIGDAAAGSQEVFKKISVHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSRLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHLVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(2840..3967)
                     /locus_tag="TVR04_000282"
     CDS             complement(2840..3967)
                     /locus_tag="TVR04_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1268999.1"
                     /translation="MVLFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKNIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIASLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTLLYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPIFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(3976..4899)
                     /locus_tag="TVR04_000283"
     CDS             complement(3976..4899)
                     /locus_tag="TVR04_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269000.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGNKLKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNQQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYEADFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDARIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(4922..5608)
                     /locus_tag="TVR04_000284"
     CDS             complement(4922..5608)
                     /locus_tag="TVR04_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1269001.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYTLVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(5605..6276)
                     /locus_tag="TVR04_000285"
     CDS             complement(5605..6276)
                     /locus_tag="TVR04_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1269002.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(6251..7609)
                     /locus_tag="TVR04_000286"
     CDS             complement(6251..7609)
                     /locus_tag="TVR04_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1269003.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHLHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYRELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPKVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKYKEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWEAFEPLISGEVRLSDLTSHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(7622..8686)
                     /locus_tag="TVR04_000287"
     CDS             complement(7622..8686)
                     /locus_tag="TVR04_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1269004.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKAIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALAKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(8683..9633)
                     /locus_tag="TVR04_000288"
     CDS             complement(8683..9633)
                     /locus_tag="TVR04_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1269005.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYHYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(9861..10025)
                     /locus_tag="TVR04_000289"
     CDS             complement(9861..10025)
                     /locus_tag="TVR04_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1269006.1"
                     /translation="MLQFTSNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKP"
     gene            complement(10554..10811)
                     /locus_tag="TVR04_000290"
     CDS             complement(10554..10811)
                     /locus_tag="TVR04_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1269007.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(11349..13388)
                     /locus_tag="TVR04_000291"
     CDS             complement(11349..13388)
                     /locus_tag="TVR04_000291"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1269008.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVQRMADFLKANRLSYNAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLIEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSVEDLVAKLAHVTFHEKIGSLAEHMDRTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEAAAVATAIREHYLPDSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLAFICARVDKMMGSAIPKDIRKAVLASSSFVVPELLARAEALVA
                     ASQLDTYKPAVESLSRVFNLAKKAADAVPIDDSLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRCNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(13758..14669)
                     /gene="glyQ"
                     /locus_tag="TVR04_000292"
     CDS             complement(13758..14669)
                     /gene="glyQ"
                     /locus_tag="TVR04_000292"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1269009.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     TFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(15035..15568)
                     /locus_tag="TVR04_000293"
     CDS             complement(15035..15568)
                     /locus_tag="TVR04_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1269010.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(15834..16058)
                     /locus_tag="TVR04_000294"
                     /pseudo
     CDS             complement(15834..16058)
                     /locus_tag="TVR04_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(16088..16927)
                     /locus_tag="TVR04_000295"
     CDS             complement(16088..16927)
                     /locus_tag="TVR04_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1269011.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLGAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTV
                     AQLALAWSISEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(17014..18162)
                     /gene="nagA"
                     /locus_tag="TVR04_000296"
     CDS             complement(17014..18162)
                     /gene="nagA"
                     /locus_tag="TVR04_000296"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1269012.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGHWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIDDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(18279..19910)
                     /locus_tag="TVR04_000297"
     CDS             complement(18279..19910)
                     /locus_tag="TVR04_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEL1269013.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLTLQQAIGIVMGANIGTTVTS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNLGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQHYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHILFNVIGTIIFMILLMPFTSFMLWLQSVL
                     ALSPEMTIAFSHGTFNITNTLLLLPFISTLAKLVTTLIPGEDEIVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTAEDRFGEKVRRYEKAVNTIDEELT
                     TYLVDISNEALSPSENEVLAGLLDSSRDLERIGDHSESLATLIEGITAKQIDFSAAAR
                     GELTEMYHLTHCLTLDAIRAIVDSDKALAQSIVERHRTIEQKERQLRKTHIERLNRGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSGQL"
     gene            20101..20859
                     /locus_tag="TVR04_000298"
     CDS             20101..20859
                     /locus_tag="TVR04_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269014.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLMFSSLSPKPAAITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAVSLKHNQEDV
                     AIKVLKAAEDNPSSELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPATPHIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPSPSPAPETPEPTP
                     NPSPQPNPQPETNTPSPQPPATEQTENTAPAGQG"
     gene            complement(21473..22441)
                     /locus_tag="TVR04_000299"
     CDS             complement(21473..22441)
                     /locus_tag="TVR04_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1269015.1"
                     /translation="MTFGKKLGFLALILSMVLVLGACGKTGLGGSSSESTKETTKKEA
                     KDLKLGVSISTTNNPYFVAMKDGLDKAAKKTGVAIKVADAQDDAARQADDVQNFISQR
                     VDALLINPVDSDAIVPVIKAANTAHIPVILIDRGSNGGEVLTTVASDNVEAGKMAADF
                     IVKKLGDKAKTFELSGVPGASATVDRGNGFNSIAKEHLTVLSSQSAGFDRAKALNTAQ
                     NMIQANKDVQVIFAQNDEMALGAAQAVKAAGLKNVLIVGIDGQPDAHQAIEKGDLTAT
                     IAQQPAKMGEIAIQAAVDHYQGKAIDKETVSPIYLVTKENVDKYNW"
     gene            complement(22456..23397)
                     /gene="rbsC"
                     /locus_tag="TVR04_000300"
     CDS             complement(22456..23397)
                     /gene="rbsC"
                     /locus_tag="TVR04_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771495.1"
                     /note="functions to transport ribose at high affinity;
                     forms a complex with RbsA2C2B; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HEL1269016.1"
                     /translation="MKQAMKYMSELTTLIALVGLMIVITIINPSFLTTNNLLNLLLQV
                     TANGFIAFGMTFVILTGGIDLSVGSSLALSSALAAGLIGGGLPVPVAIVLAICLGGLF
                     GMLNGLLIAYGKLAPFIVTLATMTIFRGATLVYTNGNPVTKGLSDSFLFQFLGQGYIV
                     GIPFPVILMFLVFVILAILLHKTAFGKAVYALGGNEKAAYISGIKLNKVKIIIYTISG
                     MMASLSGLIITSRLSSAQPTAGASYEMDAIAAVVLGGTSLSGGKGRIWGTLIGALIIG
                     VLNNGLNIIGVSAFWQQVVKGIVILIAVLLDRFKVAK"
     gene            complement(23399..24877)
                     /locus_tag="TVR04_000301"
     CDS             complement(23399..24877)
                     /locus_tag="TVR04_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEL1269017.1"
                     /translation="MKIEMTAISKSFGTNKVLEKIDLVLHSGQVHALMGENGAGKSTL
                     MNILTGLFPASSGTIVIDGVEKQFSNPQEAEAFGISFIHQEMNTWPDMTVLDNLFLGR
                     EIKGAFGLLDQKAMKEKAKRAFDRLGISIPLDLPIGSLSVGQQQMIEIAKSLLSEVSL
                     LVMDEPTAALTDRETESLFQMIASLKKAGVGIVYISHRMEEIFRVTDLITVMRDGIVV
                     DTKPTAETNPAELVKKMVGRDIDDYYPAKAAELGELVFEVENLSGECFKDISFQVRRG
                     EILGFSGLMGAGRTEVMRAIFGLDKRTAGRIRLNGQDIQVTNPVQAIRAGIGFLTEDR
                     KEEGLILDFSIKDNMTLPSHKDFSKNGFFDDKTSRDFVQKMIDRLRIKSGRPEMVVGN
                     LSGGNQQKVVLAKWIGIAPKVLILDEPTRGVDVGAKREIYQLMNELAERGVPILLVSS
                     DLPEVLGVSDRIVVMHEGRITGELSRGEATQEKVMQLATGGK"
     gene            complement(24893..25291)
                     /gene="rbsD"
                     /locus_tag="TVR04_000302"
     CDS             complement(24893..25291)
                     /gene="rbsD"
                     /locus_tag="TVR04_000302"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEL1269018.1"
                     /translation="MKKHGILNSDVAKLAADLGHTDRVCIGDLGLPVPVGVPKIDLAL
                     KRGLPSFQDVLGMYLEHVVIEKVILAEEIKTANPDQLAAILTQLDDTVAVEYVSHEEL
                     KALNKSVKAVIRTGEDTPYSNIILQSGVTI"
     gene            complement(25266..26177)
                     /gene="rbsK"
                     /locus_tag="TVR04_000303"
     CDS             complement(25266..26177)
                     /gene="rbsK"
                     /locus_tag="TVR04_000303"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEL1269019.1"
                     /translation="MSNIVIIGSISMDLVMETKRIAKEGETVFGEAFSMVPGGKGANQ
                     AVAVGRLSLDSDRITMLGAVGQDSFGPLLLDNLKKNGVSVEYVGTVPLSSGIAQITIF
                     NHDNRIIYCPGANGQVDTRTWQAEWEVLAAADLVILQNEIPHEANLAIARYCHERGIK
                     VLYNPAPARETDLDLLTFVDYVTPNEHECQDLFPELSLEEALRTYPNKLIVTLGIRGA
                     AYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFGLAISHGLNTAAALRFATLASHLSVQ
                     QFGAQGGMPRLEEMKEHEAYEKAWDFK"
     gene            complement(26170..27153)
                     /locus_tag="TVR04_000304"
     CDS             complement(26170..27153)
                     /locus_tag="TVR04_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1269020.1"
                     /translation="MATIKQVAKEAGLSKSTVSRYISQKGYVSEEARDRIKAAIEKLH
                     YSPNLSAQSLKTKKNQLVGLLLPDISNPFFPRLARGAETFLKEKGYRVMLGNLSDNPV
                     LEEEYLNVMRQSNAAGIITTHDFTKTHPEIDIPIVVVDRVNQETQFGVFSDNEEGGRL
                     AAQKVCESGANHILLIRGPLDDAENLHERFEASLAYLQEAGVRTSICDSSSFDFEAIQ
                     DEAKQALTDFPDLDSVIAPSDIHAIAYIHELHSCGKRIPEDVQVMGYDDILMSQFIYP
                     SLSTIHQSSYLLGYKAAELVYQITNQLPIDEKRIKLPVHYVERETIRRKHE"
     gene            complement(27424..28266)
                     /locus_tag="TVR04_000305"
     CDS             complement(27424..28266)
                     /locus_tag="TVR04_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1269021.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLCFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            28398..28955
                     /locus_tag="TVR04_000306"
     CDS             28398..28955
                     /locus_tag="TVR04_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1269022.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(29368..30192)
                     /locus_tag="TVR04_000307"
     CDS             complement(29368..30192)
                     /locus_tag="TVR04_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1269023.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAREGIKVVLCTGR
                     PQSGTRPYFEQLGLSDDEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATSLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLRLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAIYQLALPKDS"
     gene            complement(30197..30811)
                     /locus_tag="TVR04_000308"
     CDS             complement(30197..30811)
                     /locus_tag="TVR04_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1269024.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPRLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(30967..31839)
                     /locus_tag="TVR04_000309"
     CDS             complement(30967..31839)
                     /locus_tag="TVR04_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1269025.1"
                     /translation="MKKVMISLLILATAALGACQASHQSDQPKQEQKEPQAKKRRLFL
                     SNMNSAESQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWLQKQGDFIGTNCRINTFMLLKDTIAIKPISSDDTLLFMDEDAITTRQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHLSAVTFNDQAKMLSVVIHDQLDGDYLF
                     IGHVGVLVEHKGKHLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVDLASYRS"
     gene            complement(32051..33460)
                     /gene="lacG"
                     /locus_tag="TVR04_000310"
     CDS             complement(32051..33460)
                     /gene="lacG"
                     /locus_tag="TVR04_000310"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEL1269026.1"
                     /translation="MIKRLPDDFIFGGATAAYQAEGATTIDGKGAVAWDRYLKDNYWY
                     TAEPASDFYHQYPVDLALAEQFGINGIRISIAWSRIFPEGFGEVNAKGVAFYHSLFAE
                     CHKHHVEPFVTLHHFDTPEALHSRGDFLNRENIDHFVAYAAYCFKEFPEVSYWTTFNE
                     IGPIGDGQYLVGKFPPGISYDLAKVFQSHHNMMLAHARALVHYKEQAYPGEIGIVHAL
                     PTKYPLDPTNPADVLAAELDDIIHNKFILDATYLGRYSEKTMAGVKHILAENGGSLDL
                     RPEDFELLQAAKDLNDFLGINYYMSDWLRAFDGETEIIHNGKGEKGGSKYQIKGVGQR
                     IFDVDVPRTDWDWMIYPQGLYDQIMRIKADYPGYKKIYITENGLGYKDTCIDGRIDDD
                     ARIDYIKQHLAVIADAIGAGANVKGYFIWSLMDVFSWSNGYDKRYGLFYVDFETQKRY
                     PKKSAYWYQQLAATKTISM"
     gene            complement(33470..35152)
                     /locus_tag="TVR04_000311"
     CDS             complement(33470..35152)
                     /locus_tag="TVR04_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1269027.1"
                     /translation="MNKLIEHIEKRKPLFERISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILLAYVPNAWGFHWSKSVEALLMLPYSYSMGILGFFVAGTTAKALTDSINRQLEATNQ
                     MNYLSTMLAAMVGFLLMAADPAKEGGLLTGFMGTKGLLTAFISAFVTVTIYKLCVKNH
                     VTIRMPDEVPPNISQVFKDLIPFTLSIVLLYLVQLIVKQTLGVNVAESIGALLAPLFQ
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQAGQHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILTPIVNVWIFKFFIDVLGMNSFTANLPWTTPAPLGLVLGTNLQVLSF
                     VLAAVLIAVDVLIYYPFLKVYDEQILAEEIAGNTSHQSLTDKVAASFDTKKAQAILQK
                     HQPITAEANILVLCAGGGTSGLLANALTKAAKKYQAPIKAAAGSYGAHREILSQYQLV
                     ILAPQVASNYEDIKLETDKLGIKLAKTEGAEYIRLTRDGQAALAFVQRELEN"
     gene            complement(35156..35467)
                     /locus_tag="TVR04_000312"
     CDS             complement(35156..35467)
                     /locus_tag="TVR04_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1269028.1"
                     /translation="MTKEEITMLGFEIVAYAGEARSKLIEALEAAKKGDYDKAEALCQ
                     SANQSILEAHKAQTSLLQEEATGSDIAFSVTLMHGQDHLMTTLLLQDMMKHLIELYKR
                     G"
     gene            complement(35478..36308)
                     /locus_tag="TVR04_000313"
     CDS             complement(35478..36308)
                     /locus_tag="TVR04_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1269029.1"
                     /translation="MFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEA
                     VEKTFLLKNDEARENLLLLLKDVPLDVITVTYDVIDWLVLTYHYPVQQYLYVTLTDHI
                     YAAYHMLQKGTYSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEVTKIALHF
                     INAKGEESSPQREHSSTKKLLNQVEAALLANGITRTSTNSHFYDRLMIHLTYFIQSLD
                     RKNQGYHAMGSLEEQIKKEYPRAYEIGSAIYQLMTDLTGQELVESEKIYIVIHIQRLL
                     "
     gene            complement(36606..37598)
                     /gene="lacD"
                     /locus_tag="TVR04_000314"
     CDS             complement(36606..37598)
                     /gene="lacD"
                     /locus_tag="TVR04_000314"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1269030.1"
                     /translation="MTLTRNKKAYLEKVSRKGIISALAFDQRGALKRMMAAHQDTEPA
                     PWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTSR
                     LPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDEYINQQKQAYIERIGSECQAEEIPFF
                     LELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSAERFGVDVLKVEVPVNMAYVEGFA
                     EGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLCG
                     RATWSGAVAVYMSEGEEAARQWLRTEGFQNIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(37600..38532)
                     /locus_tag="TVR04_000315"
     CDS             complement(37600..38532)
                     /locus_tag="TVR04_000315"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1269031.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARAYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(38542..39057)
                     /gene="lacB"
                     /locus_tag="TVR04_000316"
     CDS             complement(38542..39057)
                     /gene="lacB"
                     /locus_tag="TVR04_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1269032.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGRADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKAEYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(39073..39498)
                     /gene="lacA"
                     /locus_tag="TVR04_000317"
     CDS             complement(39073..39498)
                     /gene="lacA"
                     /locus_tag="TVR04_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1269033.1"
                     /translation="MAIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTL
                     AVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIAAEVSDERSAYMTRGHNNARMMT
                     LGARIVGEELAKNIAKAFVVGSYDGGRHQIRVDMLNKMA"
     gene            39702..40484
                     /locus_tag="TVR04_000318"
     CDS             39702..40484
                     /locus_tag="TVR04_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1269034.1"
                     /translation="MLKRERLLKIIEKVNANGIITVHDIIEQLKVSDMTARRDLDELE
                     KAGKLVRIHGGAQSIAMPQKLERSNTEKLTVQIEEKKEIARYASQLVNDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFNILHKSESVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(40900..41451)
                     /locus_tag="TVR04_000319"
     CDS             complement(40900..41451)
                     /locus_tag="TVR04_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1269035.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRAQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(41464..42414)
                     /locus_tag="TVR04_000320"
     CDS             complement(41464..42414)
                     /locus_tag="TVR04_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1269036.1"
                     /translation="MNENTKRLTDPIVLEKIRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLALSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(43284..45515)
                     /locus_tag="TVR04_000321"
     CDS             complement(43284..45515)
                     /locus_tag="TVR04_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1269037.1"
                     /translation="MAKETFMLEGMHCTSCALAIEQAVKQLPGVEDVVVNVTTEKLSV
                     TYLAARLTSAEIIQAVRDAGYKAELLDETDVRGQMDRLEEQAHQTWYRFVWSALFSLP
                     LVYLSMGPMLGLWLPDALSPRLHAISYGLVQLLLTLPVLFLNRQYYVNGFKALVKKHP
                     NMDSLVALATSFAFSYSAYSFFKIVTGMDSFVHQLYFESVVVILTLITLGSYLESRTK
                     GRASQAIQKLLSLTVNDVRVIRQGEIQLIPLEQVTSEDICFIQPGERVAIDGLILDGQ
                     SAVDESMLTGESLPVDKQAGDHVFAGTINGQGALKVQPSRLGQDTLLAQIIQLVERAQ
                     QTKAPIAAIADRVSGVFVPIVLGLSLLSFLFWFFVMRESLDFALTVATAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKTYQVQTIVFDKTGTLTQGKAQLQHIVP
                     LAADKEQALQEVASLEQYSQHPLGEAIVKAARDQDYDLLTVTDFQSFVGLGVTGSIDQ
                     HRLAVGNSQLMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADVGISIGSGTDIAIEAADIILMTSSLLDVVDCLELSLQTI
                     RVVKQNLFWAFIYNSLMIPIAMGALHIFGGPLLNPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(45515..45949)
                     /locus_tag="TVR04_000322"
     CDS             complement(45515..45949)
                     /locus_tag="TVR04_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1269038.1"
                     /translation="MDTISDAEWEVMRVVWANGDMKSSEIIAILHAKYHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRLELAILRERLDGMCQRHHSHLLLALLKET
                     PMTLEDIQNFQVLLEAKAAQAVPDVLCHCLPGQCYCQKKEEH"
     gene            46179..47201
                     /locus_tag="TVR04_000323"
     CDS             46179..47201
                     /locus_tag="TVR04_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1269039.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKTENITQPKDIILLS
                     PWLDVTLSNPDIPKYESSDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDIKKFDDMLAKSNHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTINKN"
     gene            complement(47273..47623)
                     /gene="rbfA"
                     /locus_tag="TVR04_000324"
     CDS             complement(47273..47623)
                     /gene="rbfA"
                     /locus_tag="TVR04_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1269040.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(47813..50689)
                     /gene="infB"
                     /locus_tag="TVR04_000325"
     CDS             complement(47813..50689)
                     /gene="infB"
                     /locus_tag="TVR04_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1269041.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKDVQAGSAKDKQVAEQKAKAAKATTPQPAAPQAAEKPAATQEAPQPV
                     AVKPKSRNFKAEREARAKEQAARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQN
                     QQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDFK
                     ARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAPA
                     KATEPAEPVASIAAAPVAKPVDKRRKKQNRPDKAHDRDHGLEDGQKKNKKSWNSQNQV
                     RNQKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIK
                     REPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDS
                     YLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGK
                     KITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVA
                     INKIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEV
                     EELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTND
                     LGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQ
                     RVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAI
                     NESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKL
                     DPEYQEKVLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLAS
                     LKHYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEIIRK"
     gene            complement(50709..51011)
                     /locus_tag="TVR04_000326"
     CDS             complement(50709..51011)
                     /locus_tag="TVR04_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1269042.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAAIGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(51004..51300)
                     /locus_tag="TVR04_000327"
     CDS             complement(51004..51300)
                     /locus_tag="TVR04_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1269043.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAYVDHKVKRRELGLE"
     gene            complement(51316..52470)
                     /gene="nusA"
                     /locus_tag="TVR04_000328"
     CDS             complement(51316..52470)
                     /gene="nusA"
                     /locus_tag="TVR04_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1269044.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTDEEV"
     gene            complement(52580..53062)
                     /gene="rimP"
                     /locus_tag="TVR04_000329"
     CDS             complement(52580..53062)
                     /gene="rimP"
                     /locus_tag="TVR04_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1269045.1"
                     /translation="MNIANTAIIDIVTQTVEPVIKAPYELVDIEYDKMGSDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
BASE COUNT        15522 a        12884 c        10229 g        14841 t
ORIGIN      
        1 tactcctaac gataagcttt ttcgtattct ctattacttg gtcccaatac tatttttcta
       61 gctttaggct ggctttgtta atctaaaata atatcagata atttccgttt taattaaaaa
      121 aaaaaaaaaa aaacgaaact acggaagcta attatcagaa aatgattcac agcttagagt
      181 caccatgtta agctattcta cggagaagaa aggtttagga atgactattt ctaaactcaa
      241 aggagagaaa catgagaaaa acaatgaaga agatgctggc agcctcgaca gtctgcatca
      301 tcatgtcggg cagcttcatc ggcggatcag ccagaatcct agccgagcag tattatggat
      361 ggaatgacat aaacagcaga acagaatccc ccttctttct atatgtaaca cctaaaaacg
      421 aaacaactag gaaagtcgga aaagaaggca ctgtagtata ttgctttaat agagatttac
      481 attggcctga aaattgggaa caaggtgcga gtaaaagacc agaaaatctt cccctataca
      541 ataagctaaa aggaactgac gatgaattta ggaaagcagc atctaagttt cgaacaacta
      601 taagtaatat aacaaattcc ttagttgcag tattaagcaa ggattatcct actgttacaa
      661 gtgttgaagg actagatgaa acttctagta gaaaagtaac acagttagct atttggtact
      721 ttagtgattc atttgataag cagtggttta aaggtaacta caaattaaat gataaagaag
      781 atcaagctct tcaacattta atagatcttg gggagcaagc atctagagaa aagaaggaac
      841 aaagccatac cttagatatc tatcttcacg agtcaagtta tacacaatat caaaaccttc
      901 ttggctcaac tctaatacct aaagttgatc ctcagccgga tcctggccct aagcctaagc
      961 cagatcctga gccaatgcca gatcctcagc ctaaacctga gcctaaacct gagcctaaac
     1021 cggaacctaa gccagaacca atgcctaagc ctgagcctaa gccacaacct gagcctaagc
     1081 cagaacctaa gccacaacct gagcctaagc cagaacctaa gcctaaaccg gaacctaagc
     1141 cagatcctga gcctatgcca gatcctcagc ctaaacctga gcctaagcca gatcctgagc
     1201 ctaagccaga tcctcagcct aaacctgagc ctaagcctaa acctgagcct aaaccggaac
     1261 ctaagccaga accaatgcct aagcctgagc ctaagccaca acctgagcct aaaccggaac
     1321 ctaagccaga accaatgcct atgcctaaac cggaacctca gccagaacca atgcctaaac
     1381 ctgagcctaa accggaacct cagcctaaac cagcgcctca accagaggtt aagtctcaaa
     1441 aaccaaccaa gccatcaaac actactagcc agtctagcgg caagggacta ccaagaacaa
     1501 atgaagcagg cagtctaatg acaggacttg gaacaggctt actctctctt ctcggattag
     1561 gcttcctaac aagacgcaaa agaaaagact aagacactaa aagattatct gtagtcgttt
     1621 agttgatcag tatctagtct aatacaacac aaaagcctta tcgtgccata aatggaacga
     1681 taaggctttt taagctttgt tcaaaaaggg gaagacaact tagtctaacg atgtaaaggc
     1741 ttcatcagca cgcttgctag taccattaag gtcatagctg ctacaaacaa ggccaagaaa
     1801 taaggccaag cctcacctag attaccgcca ttttgaaaag tgctgatgat ggttagcacc
     1861 aaatgttgtg ggagtagctt tccaatcgcc tgcatataag gcggcgtaat actaagcggc
     1921 cataaacacc ctgctaacat agaggttggc atcacaatca gattagccaa ttgactgctt
     1981 tgttgcgcat ttttagaaac cgcaccaatc attaagccaa agcctatagc taacaaacta
     2041 taaagaaaga aggtcaacaa aacaatggct gttggaatgt aaaagctgac atttgctacc
     2101 ctgagtaatc ccagcataat cactatttgt atcgcaaagg caacaatacc aacacagaca
     2161 tagctcagca tgtattgaag ccttgatagc cttgataaga ctaagcgatt gtagatttga
     2221 ctggacttat caagcaagat accaccgtac aagacactgg tactgcctag cattaggatc
     2281 aataaaaagc cagttgttgt cgaggaaaca gacttacttt gggaacgatc agctagggtg
     2341 atttctttga ccttgtagga tagcttcgtg ttatggactg aaatcttctt gaaaacctct
     2401 tgactgcctg ctgccgcatc accaatgata ttgtaattct ccaagagata attggcctgc
     2461 gccttgaacc attctgttat ttgactatca gcaatcgaac gcagtgcaag cttttgagta
     2521 tctcctttta gaaccttctc accaaagccc ggctcaatgg tcagcacagc ctctagtgtc
     2581 ttggccttta ggtattgatc aatagccctt tcctctagcc tagtatatat ctgatacttt
     2641 ttattgtgct ttaattgcga cacaaattgc ttggaaacct gactcttatc cttatctaag
     2701 atcccaatct tggcttgact tccccctgta aagctcaagg acaaggccag cattgttgtt
     2761 agcataggca acaggataaa ggtgatatag cttgtttttt tacgtctaat tttgataaat
     2821 agagctttaa taaaaggaat catgctgcca cctgctttct cattctgacc aaagcaaaga
     2881 ggataaaggc tgttcctata ccaagattaa ccattaaggt aaccggtatg ggattggatt
     2941 gcccaccaaa aataagataa aacaagctat cattgaccca ttttatcggg gaaatattag
     3001 acagctgatt aatcaaggca ctatttaagg ttgataaagg aatatagctc cctcccaaaa
     3061 aggcaaagat cggaatgact gcattagacg ctaccgtcaa aaaggattga tttctaatac
     3121 cagtcgcaag tccaataccg atggcaacag acagataaac taacgaggct gtcacaccga
     3181 taatctgcca gtcattggtc ccccaattaa cacgtaacac aaatcgggta aagacataaa
     3241 gaagggttag ctggactgct gttgccagca taccgccaat taattttcca agcaaaatag
     3301 cgctatttga aacccctgtc aaataaatgc ggcttgccac cccttgctga cgatctgata
     3361 gcaccagatt catcgccgac ataatgctat aaaaggtaat catggtaaac atggaaatag
     3421 catagtaatc cgctgagctc atgcccttac tggtttgcac agagctagag gcgatatagt
     3481 ctatctttct tttcttgatg ttgctaatgg cctctggata aaggctagca atcgaatcat
     3541 aggtcttggc gttatccaca taaatgttga caagcatatt aatcaaatca gcgttctgtt
     3601 gattaatact gttggtggtc acctcaatgt tttggtcact cttaacctct agagctgctg
     3661 ttaaggcgcc ctcgctgacc ttttgcttag ctttagcgat attcttggtt tctttagcct
     3721 ctaggtgaag ctctttgttt aacagcttta aaaacgtgat aaagttcttt tgatactctg
     3781 tttccttgcc ctcaagctgg taacgaaccg tcaatttagg aacagtagct gccgtattaa
     3841 agctggactt aaaagcaaag cttaaaatca gaatcatcaa gataggaaaa actaccatca
     3901 tcaacaaggc cgtccgatcc ctaaaaatct gtaagctttc ttttttgatt aaatgaaata
     3961 agaccataac aacccctaat ctcttagctt cttaccagtc aaatgcagga agatttcttc
     4021 taaattcaaa tgcttatgcc taatctcact aaaagcaata cgagcatctg tcagctgacg
     4081 gacaaccgag ccaatgtctt catgttcaat caagagaact gcttcaagct cattatccat
     4141 caatctccaa ttgggcttat tagagagatc gattgcttgg tcagctgcga ctgtcaccat
     4201 gatttgcttt gtgaaatcag cctcatagcg tctttctagc tcggcctgac tcccctcttc
     4261 aatcacctga ccatgatcca taatgtaaat gtaatcacat aaggcctcaa cctcttccat
     4321 gtagtgggtc gtgtagatga cagtggctcc ttgttggttt aacaagcgaa tagactctaa
     4381 aatatgatta cgagactgtg ggtcaattcc taccgtcggc tcatcaaaga tgattagctt
     4441 aggagaatgc accaaggcac aggcaatgtt taagcgtctt ttcatacctc ctgaaaactg
     4501 gcttggaaac tgacttgcct gcgactttaa ccctacgaac tccaagcttt ttaggacctg
     4561 ctccttgagc ttatttccct ttaagccata gagagagccg aaaagctcaa cattctcata
     4621 ggctgttaaa tcaggataaa cagcaatatc ctgagggaca tagccaatct tggaactaat
     4681 ttttcgaata gatttataag attgctgtaa aacagtcact tcgccagcat tcaaagggat
     4741 taatcctaaa atagcattga ttaaggttga cttaccagcg ccattaggtc ctaaaaggcc
     4801 atagattctc ccttcctcaa ttgtcagtga gacatgatct attgcctttt tgccgcctcg
     4861 atagaccttg acaacatctt ttaactctac aaaactcata tattattcct tctttccaac
     4921 tctaacgctg ctctttaaaa ctaattaaca gataagttaa ggtcaataaa agcgaaccaa
     4981 tcaaccaacc atataataag gctgctgtca cacaccagac accaatcaca ctaaagaggc
     5041 atagggctag tagctgctgt agccagcctg agtaacgaca ggccttgacc aaggtatagc
     5101 ccaaaaccac aagcgtaaga cctgccactg aatcttttcc taaaaagaga catagaccta
     5161 agtaacaaaa agcatcaacc agtgtgacaa gacttaacaa aagaaagcta gctgctgccc
     5221 tatctggttt aaaggctagc caagtcattt ttcctaagag caggcgactg tcctttttca
     5281 gcataagatc aaaaagcaag accaaaacca acagggttag ctctaccaag gctatgctat
     5341 acaatagcac ataacaaatg atttcccagc caaaggatac gcgacccaaa aaggtcagca
     5401 aaccatcaag agctaaagca tcagaaaata atagacaaac aagcactaga ccaagctgga
     5461 ttagaccaag caatagatca agccattgct gataggacat tgccctgatg tgccttaaat
     5521 gccatctgac taagcgccgt cttttatgac ttgttagaaa aagggtcact aggattaaaa
     5581 aggatagcaa tgctagtatt atgatcatcg taccaccttc ttatgcattg attgaagatg
     5641 actcaagcct tcaacccata aattgcctcc aacatgaaca agcaacacca gccataagct
     5701 ctgactaaca taataaatac ttccgtaaat aagaccagtc agtattttgg cgtaaaaaat
     5761 ggatctgccc atcaggaaat ggtttagggc atagcacagg ctggtgatca acaagacaag
     5821 agcaattggc aatcgccatt gaagccacaa gatgttaaac caaatcaaac gataggtgat
     5881 ttcctcacag caggccaaga ccaaaggata gcctatctgt ggccattttt gtgtcgttcc
     5941 gacaaatgat aggactaagg gaagccactc ttttttttgc cagcagcgac taagatgtaa
     6001 aaaagcaacc tcaacaaaga gcacaacaaa gctcaagata aaaccaatga tcaaaagacg
     6061 accatcacta tgacctaagg gcgctttaat aggaggtgac agcaggtaaa tccctgttaa
     6121 gacaagggca taataaacca gtacagctct taaaaagcct attagattaa agctatagct
     6181 atcacgaccc tggccaaaaa tagcctgcat cgcgatcgac ggacaaaagg tagccattaa
     6241 aaagcatagg ttaaggcatt gggtgtacaa aggcatttgt cacacctcca aactgtctca
     6301 tacgtggatg attagcaaat ggaaaggcag gaatacacat ctcaagaagc tccggagtga
     6361 ggacacgtgt cacgtaccag cctttttctg aggcctcagg aggagtaatg tctaaaaaga
     6421 cagcattggg acttactttt ttagtgtaag ctagtagtgt ctttaaatcc tcttttttat
     6481 ctttcccagc atgacttgtc aggtcgctaa gacgaacctc tcctgaaatc aagggctcaa
     6541 aggcctccca tttaagctcc tgatcctttg gatgagcata gtaaaaaaca ttactatcta
     6601 ggtctaagaa caagggagaa tcactctcag cattttgtgt tgacgttgga ttataaaaca
     6661 aattatagta atagctatag ctaatagctg aggcctccat gattcctctt aacagggtat
     6721 gcttaggatc caagcctgcc tgaaccccaa ataagagata aggaccttcc ttgtatttgt
     6781 ttttgaggat aataccaaag gtataaagcg gattatcctc tccaacagtc atgtcaatag
     6841 ggataatctc atagagactg tccttaccaa gtctagcttc ctccaaaaga gctagaattt
     6901 ccggatcatc aataatcacc ttgggacaag gctttttagt atgccagcta agcatcatag
     6961 agtcaatttg aatatactca atcaagctat tacacatggc tgcttctagt gttgtatgag
     7021 aggctgtccc cgttgaaaaa cctggaatga tgtgcttttc gcctacagcc tggttggtct
     7081 tatagccaac gcaaagcatt tgggcaggca catacatctc cttatcttca aaaaacatcg
     7141 gacacttaac ccagcccaag acatcgtctt gtgtcaccat tttatcacac atgatcatgt
     7201 gcaaatcatg acaacggtca atttgttcct gtgtaaaaac ctgcaaatac tctaagggca
     7261 tgacaggatc tgtctggctc aattctctat aagaagcata aacaatccgg tctgataata
     7321 attccccagc aataacagtg gcataacgct caatgctttc acccaagtat ttgatcaagg
     7381 cctcctcata atgactgcca taaccgatga tatgatagct cacctgactc agctcaccaa
     7441 taaactgctt gtggtaatca ggcatctgac ctgtcacact ctttaggtaa acatcatgaa
     7501 gatggttaca aataggaacc tgagactgat ttaagatacc agttcggtta ccactaagtc
     7561 cctttagctt atcaaggata tggttgaacg aagggtaata atgtagcatt gttagacctc
     7621 cttatgactc ttcttgaagg agttttttaa caatctcacg tgttgaaatc tgttgatcct
     7681 cataccttaa ttttgccaga gccccttgtg tctgagaatt agacattttc aaaatatcct
     7741 gcacctgaat ctcaagcgtt ggcaaataga cacttaacaa acgcccttca aattttgagc
     7801 ttcctgtttg agctataata aaggcctcac tgacaaccag attcattaac acatttaaca
     7861 aaggcacgta agaggagcta acaggctgcg ttggcggcag ctgctgactt gcaaagcgct
     7921 gataaagcgt atggtcctgt agacgtgcca gcacccttct ctccaagcta tcaaaatcag
     7981 cactatgagg aggatttaag gtacaagcat ggataaatgg cccatcaaca aagccaagca
     8041 ccaattgttt tttcaaggcc acactgattt cattaaggtg acgcagcatc ataatattca
     8101 accggccttg acaaataaca atactctgat agtctgcgag cttctcagat aagcacttca
     8161 tgttgcggtg gtgctccaga gcatctaaac gagaggtgac atctgtttct tgaatgagca
     8221 tttttagctc atcactggcc acctgaaggt ttaaattcag gtgcttggcc aatagctcag
     8281 cagattcgtt gacatagctt gaatcactga taaataagac aggtgcagta tccttagcct
     8341 gtcctgattc agctatgaaa tgataattac ctgttaagac cttcatgata ttttcttcaa
     8401 gagcataagc gtcctcaagc atcaataggt cgttgtaata caaggctgtg atgacctctg
     8461 acaattttgc aaataaatca gactctagtg ttttttcgta ggtatcagta tcaatagcct
     8521 tcccgttaaa ccaatcggag atgatactgt agtaggcttc ttttaaggct tgtggctctt
     8581 gtgcaatgtc taaaacagct tcattaaaat cccataggcc ttttctaaag caaaacgtat
     8641 cgtcaaattg cacaatgcga acattgctat ttaattgata tttcattgag actccttatt
     8701 tccaataatc gtcatgtgaa tcacatgctg ggtcagtcca tctaagccta gcttttcttg
     8761 gaggtattcc ttattgtatc ctccaatatc aacacttcca tataccaaag ctgttgagac
     8821 caattgaaca ttttgagcaa tctctccagc ctcaataaag gcataagcgg tagcttgatt
     8881 tccatattta cgtgtgtttt tgatgtaatg ataaacatag ataagaatga cattacagtt
     8941 ttcggcagtg atcggtccat attctgcaaa ggctctaata tcctcctgat cactaagatg
     9001 atgacacctc agcgcgtgct gataaggaag gtattcataa aaaccgtcct tgagtgtttc
     9061 tacgtttctt gcatagaaaa ataaggtgat ggggtacaga cccccaccag aagcacaatt
     9121 tcttaaggct actgtcttag tcatgccttc tttgatgatc gcctgagagc tgacaccaca
     9181 agcataataa agcaaatcag ccaaatcctg caaaggcatc tcctcatcta taaactgcct
     9241 atgacttctc cggttggtga tacaggttga tagggctgct gagaccttct tagctttagg
     9301 aagtgctatc gtgtttgccc tatcctcaaa atagtcacta tttgaaaagg tggtcactgc
     9361 agaatccgta aaaaactcag ccacactggt cttaaaccct aggtaattgt tattagcctt
     9421 gtaattcatc aaaaaccgtt ggctaagatt gtctgtttca tcaggcatca aatgctgtgc
     9481 cacaagctgt tttgatgttt ttaataccgt ttgatgatga taggttgata acgataagtg
     9541 attggtatta aattcaaata actgtcgtgc ttcttctctt gttaggtcac tttggttatc
     9601 cgaacgttgt ttttccttag aaaaaaatgg cataactgtc ttcctgtaat atattaataa
     9661 ataatagtaa ttagcaggta ccgactagta cctgctaatt actacaagac gttgacatca
     9721 agctgattgt cttcgtctct tgtcatgtaa cacccctatc caacaccagc taacaccatc
     9781 aattacaaac tgtaacctta gtcgctagca aactaatgat tgtgatctag ctattaacta
     9841 ttaaatagaa gtattaaagt ttacggtttt ggctcagctg caccataatt gttgtttatg
     9901 gtagtattgc cccatgaagc tgagacgcag caacaacaag aacagcaaca gcagcaacca
     9961 ccaggagcaa cttgagttgt ttctgctaca ctagtagcta agatatttga agtaaattgt
    10021 aacataatgc ttacctcctt atatcgcctg atcggtaaaa caaaacactg ataagagtta
    10081 aatgagaata cctctcaact gatagcaaaa gcaatcatga gccagtatcc agcaacacaa
    10141 ggctagctat tttgtatcgc ccttgttaaa gtgaccattc aattcttacc aactatatta
    10201 tattaaaatt caagacatat gtaaatgctt tctttaatat tttcttacaa aaatgtcatt
    10261 atttttgcag aaaggtcagc ttattgagct tgacaaagtc ttaagcctat ttccttaatg
    10321 gcattcagaa aatatcagtc tttttaatga aacgcattaa aataggcaga gataagaata
    10381 tctctaccta aactgtattg atgagacaga tggttagtgc ctcacaatta accatttcta
    10441 aaaataatga ctcttttgcc gaaagaccta atgattaaag ctatttgtct tcgtttatct
    10501 ttttctcatt agtaacatta aatcatggca aaatatttat attcatttaa taatcaagat
    10561 tccggatcat caagtgaccg tccatgcaga cctttttcgc gctgcacctg tcttaatttc
    10621 tcaggagtaa catcgtttcc gtcttcatca acaatcttaa tgccttcaat gtgatggcgc
    10681 actgagcggc gatagccctc aatgtattcc tcacgcagct tggcctgctc taccttttca
    10741 ggaccagtca agccaactgt ttttttcttt tttgcaagct cgttaatacg agcgattttt
    10801 ttaggatcca taaatcacat ataagggctg caccaaaagc agtgggcagc tgatgaggct
    10861 tgatgatggg ctagacagtc tctttaggac cgttactagg acctttcaag tcctttttca
    10921 ccagctttgc cagcaagggt ttcctgcaaa tggggctgcc tctaatcctt tctctttcgt
    10981 ttgtgacata gagtactgca ctctttttgt ctatatctaa ggctgtgcca gcagctgctt
    11041 agccttatgc ttctgctaag aaggctgtag ctaacttctt gtgaaaagct aaaatccatg
    11101 ctcactttac taacagcgat cctgatgctt ttattgacca ctgaccagca cagctattgc
    11161 tagcaaagct agcccaagac gatatctcct agcaagcaag agggactgat ttgactaagt
    11221 atcaattgct tgataagtct tgagtgctta gggaaggact tatcccaagg caggtaatca
    11281 gtcacctata tcatctaggg aatacgaaca gctaacacag ggcgatgtgc ttaatcttac
    11341 acagcgaatt atttagtgtt taatcggtca aaggccgcaa tggtctctac ctttttaacc
    11401 agctctgcta acagcgctaa gcggttacat ctaatggctt cgtcctctgt catgaccatc
    11461 gtatggtcaa agaagtcatc aataactgga ctaagggcaa agacctgagc tagctgttct
    11521 ttggctgagc cagataacac tagtgaatca acagcctgtg ccagagccct ttcgtagtca
    11581 ttttcaaaga gactgtcatc aatcggtaca gcgtcagctg cctttttcgc tagattaaag
    11641 acacgagaca gcgactcgac agcaggcttg taggtgtcta gctggcttgc cgcaaccaga
    11701 gcctccgctc ttgctaacag ttctggtaca acaaagcttg agctagccag aactgcttta
    11761 cgtatatcct ttggaatggc tgagcccatc attttatcca cacgtgcaca aataaaggcc
    11821 agcacctcag ccttatgctg ataggtcaag ctatcaaatg acagctcata taggctatca
    11881 atcagcttat ccataggaat gctccagccg aaatgctcaa gaattcggac gatcccctga
    11941 gttgcacgac gtagggcata agggtcattt gagcctgacg gtatcaaacc aacagagaaa
    12001 aaggacagca gggtgtctag cttatcagca agagcaagaa cagcaccaac ctttgtttca
    12061 ggtagctctc cttctgccga atccggcaaa taatgctcac gaatcgctgt tgcgacagca
    12121 gcagcttcgc cagctaaaag ggcgtatttc tctcccataa tgccttgtag ctcatcaaat
    12181 tccccaacca tgccagttag caggtcaaat ttataaatct gggcagcacg agcgacagca
    12241 cttttttctg cttctgagag tccagcctgg tcagcaagaa aggctgcaat aaccttggtc
    12301 cggtccatat gctcagccag agagcctatc ttttcatgga aggtcacatg agctagctta
    12361 gcaaccaaat cctcaacaga tagcttttgg tcctcacgcc agaaaaattc tccatcttca
    12421 agacgagcaa caagcacctt ttcattgccc ttaatcacat tttgaagatg cttagcatta
    12481 ccgttacgaa cagaaataaa attcggcatt agcttgccag cctgatcacg cacgacaaaa
    12541 taacgctgat ggttcttcat tgaggttact agaacctctt ctgggatttc caggtacttg
    12601 ggatcaaaac ttcccatgaa agcagttggg tattctatca ggttgagcac ctcatttaag
    12661 aggtcctcat caatatccac ctgaaccttt tgctctgctt cgatggctct gatttgtgct
    12721 atgatcatct cttgacgctc cttagcagag gcaatgacaa attggctgcg caggtcagcc
    12781 tcataggaat cagcacttgt aatgctagtc tcttctccaa ggaagcgatg tccgcgactg
    12841 atacgtcccg aatgaatgtc taaaaagtca agctccaaag gctcatcatc taacagtaca
    12901 atcaagctat gcaccggacg aatatagtca aagctattgt tagcccagtg catgctgact
    12961 gggaaggtca aggaagcaag aacctctggc accgctgcta agacgtcctt agcctgcttg
    13021 cccgcttcat gcttggtgac ataaacgtat tcctcacctt tgacctctcg gaattcgatg
    13081 tcatcaacag tcaagccctt tccacgaaca aagccctgag cggcttttga aaattgacca
    13141 tctgcgtcaa gagcaatttt tttagaaggg cccttaaaat cctctgtcag atcagtctgc
    13201 tgatcagcta agcccagcac acgcaccgct aaacgacgtg gcgttgaaaa gccttcgatt
    13261 gcgttatagc taagccgatt ggccttaaga aaatcagcca tacgctgcac aagctgcttt
    13321 tcactaggtg tgacaacgta ggcaggaagc tcttcaagac caagttctac aagtaaatct
    13381 tttgtcatca ttaaaatcct atgggtatca aatctaaaaa agtagatcaa accaattcta
    13441 gcatgccttg ggcaagcctg agcgatcctt tgtctacaag atttgtccca tctttctttc
    13501 ctttcttcaa gttatagggt aggtttagga tactaaatca ctagctccta atcctgcaag
    13561 cctgctaata agctgcctgc ctgttagaca agaggcctta gcagaaagac tgagcttgac
    13621 aggactagtt accaggcctt taagtctcat cgcttttaaa aagcacctac cagataggta
    13681 agctgctagc agcaactaga gcttacaaga tcatacaagc tgtattgact acaaggaact
    13741 agtttagatc cagctgctta gtcctctgcc agcaaggcta ctcggctagc atcatccaac
    13801 aatgggaagc caagcttttt acgctctgca acaaaggttt tagcaacgct acgagctaaa
    13861 tgacgaatcc gagcaatata gccagcacgc tctgtcacag agactgcacc acgagcgtca
    13921 agcaggttaa aggtatgaga gcatttcaaa acatagtcat aggctgggtg gacaagccct
    13981 tgtgctaaag cacgctctgc ttctttttca aaggtctcaa agttttcaag cagcatgtcc
    14041 tgattggata cctcaaagga atacttggaa tgctcatatt ctggctgaag aaaaatctcg
    14101 ccatacttaa caccaggtgc ccattcgata tcatagaccg aatccacctc ttgaatgtat
    14161 gaagctaagc gctctaggcc ataggttacc tctgctgtca ctggtgatgt tgctaggcct
    14221 cccacctgct ggaagtaggt aaattgtgtg atttccatac catcaagcca gacttcccag
    14281 ccaagtccag ctgagccggt tgaaggattt tcccagttgt cctcaacaaa gcgaatgtca
    14341 tgctcaagcg gatcaatgcc tagccgttcg agagattgca gataaagctc ctgaatattg
    14401 cttggagaag gcttcatgac cacctgaaat tgatggtgct gatacagacg attgggattt
    14461 tcgccgtatc ggccgtcagc aggacgacga gatggctcca cataggcagc attccaaggc
    14521 tctggaccaa tagcgcgaag gaaggtataa ggactcatgg ttcccgctcc tttttcattg
    14581 tcataggctt gcattagcat acaaccttga tcattccaat attgctgtag cgtcaaaata
    14641 atctcttgaa aggtaagttt gttactcatg atttcctctt tctatttttt atgtcttgtc
    14701 gcaggcgcta accaagagct ggctatggct tgactgctgg ttggctctta aacagctttt
    14761 caaagagaaa aaccgcgcct atagccacct acacctaaag gcataggggc gtcaaaacgc
    14821 ggttccaccc taatttattg cttcatttga tcttgttgat gaatagatgt caagcaggct
    14881 acaaacacct gagcctgccc tttagagaaa gcgccaacca gcagccccat cactcggctc
    14941 tcaccagccc cgagctcgct ttagatcaga aacctgctat tttctttccc actgattagt
    15001 ctatcacaaa atcctatgat tgtctaatca gctattatga ttttggacga gttccgtttg
    15061 gaataataac ctcagacaag agcctatttt cttcacgaat gcgcaaataa atcacaataa
    15121 tatagcaagg gaaaagcagc attgccgtaa tttgagcatg gcaaagcaaa gcaatcccaa
    15181 caagctctgg agcaatgttt aaaaagtaat tggggtgctt aacagtctta aagagccaat
    15241 gatcgacata tttatggtct tttgccagca tcagcttcac tgtccaaata tctcccaaga
    15301 tccgagttac ctcatatagc acagctatcg aaaaaatcat cagcagcaag ccaagaaagc
    15361 taatgccatc aaacttaatc tgcttgagca atgcctctgt cacagcaaag acataaatca
    15421 tgatatgcag cagggtcaaa aacttagtgt tttgcgcacc aaattccttg cccccattag
    15481 ccaggatagc cttctcgttt ttgatcgatt tttttaagaa tactaaacga atagcaaaca
    15541 tcaatagcat caataacagg ataatcaaag taagactcct ttattctagt ttaatctgtt
    15601 tctttcacga aacactaatt aagattatag ctaagttaca aagccttgtc aaaccgtttt
    15661 caaaaaaaga tgtctttctt tggtctctaa aaacaagagg tcgtcacaca gcaccatcaa
    15721 gagacctcat caaagcttta aggtcgtacc aaatcaccat caaaagacag ctcctagact
    15781 cagtcaattc acgagcagca agcagcaccc aagaggcatt ttgcaggcct gacctacttt
    15841 gcctgtcgta aacacaaatc ttcaatatgg taaatagcgt cacattgcgc tgcaacctca
    15901 tcgctgtgtg ttgccattaa gacaatcata tcctcagtct gacaagctct gatggcttgt
    15961 aagacctcct gctcagcctc aatatccagg gcgcctgttg gctcatctgc caataacagc
    16021 tgcggtgctt tgaccaaagc acgagcaaga gctactaagg caacccactt agtccctgca
    16081 gctcttgcta aaagtccttg gtatcaggat ctgggatagc tgacataccc ggcaggcaac
    16141 gaatgcgctc tgaatcctct gggctaatct cacaatcaaa aatagccata ttttctacta
    16201 tgcgttcctt gtgcactgac ttaggcagag gaataaagcc ttcggaaata gaccaagcaa
    16261 gggctagctg agccactgtt ttgttgtatt ttttagctaa ggcctgcatg gtatcatcgg
    16321 taaatatctc tccttgtcct agcggactcc aggcctccaa taaaatgtga tgcctgcggc
    16381 aataatcaac cgtctctttt tgatagcagc caggcgccaa gcgaatctga ttgactgctg
    16441 gtgtaatggt tgctgtctgt ttaagagcct ccagatggtg aaccataaag ttgctgacac
    16501 caatcgagcg aaccaagccc gcttcaacag cctcctccat ataagaccaa gctgctgcat
    16561 tggctgcttg ccagcaatcc ctaagagcct taggatttgg ccaatgaatc agataaaggt
    16621 ctacatactc tagtccaagg cgctcaagag aggctgctaa ggctgcctta gcgccatcat
    16681 agctatgagc atcattccag agcttagtgg taataaagag ctcttcacga ggaacgcccg
    16741 aatcccgaat ggcctgtcca acactttttt cattgtgata aatggcagct gtgtcaatat
    16801 gacgatagcc tgccttaatc gctcctaggg tggattggta ggcctcctca ccatcagcag
    16861 ccttaaaggt cccaaagcca agcactggaa tagcaagacc attagccatt gttactgttt
    16921 taatcatatc taaaacctcc ttttttattg tagcacaatg ataagcaaag caaaaagaat
    16981 tgagctgatc accagcccaa ttcctttgct gtatcaagcc tcaaaggcct tttgaccatt
    17041 taggtaggtt gctactaatt ctaagtcctt atcaagaaca ataaagtcag cagcatgacc
    17101 tgccttgatt tggccacaga catcatcaat accaaccgaa gcagctggga cgtaagagga
    17161 catgtgaatt gcttctgctg gacttgcaat tccccaggca acaacatttt taatgccgtc
    17221 ctttaatttt aagatagagc ctgctagatt accactatcc ttcaagcgag ctgtgccatt
    17281 ttccacaata accggaaact ctccaagcat gtaatcacca tctggtgaac cgcctgcacg
    17341 catacagtcc gtaatcaaag ccacatgctc atgacccttt tgctgcatca aaatatcgca
    17401 agcaacaggt gagacatgat gaccatcgca gatcagctct gcaaccgttc caggaatatt
    17461 ataaacagcc ccaaccatac caggctcacg atgagtcaag ccacgcatcc cattgtaggc
    17521 atgaacccaa acactagctc ctgctgctac tgccttttta gcctcagtat aggtaccatt
    17581 tgagtgacct aaagctactg tgacaccctg cttggtcacc tcagagacaa atgcttctac
    17641 accatcacgc tcaggagcca aagctatttt tttgatcaag cccttagctg ctttttgcca
    17701 agctgcaaat tcgtctaagc gaggattttt catatatatt gggttttggg ctcccttgta
    17761 ttcctcagtg aagtaaggcc cttcaaaata aatcccctga atctttgctc ctttgacctg
    17821 atcagcaaca gaagcaacgg ttgcagacac ctgctctaga tgctcaaagg ttgacgttag
    17881 ggtagtcggt aagaaggagg tcactcctgt tgataagaga ccctcactga tggcatggag
    17941 accttctgct gaattatcca tcacatcagc accagcatag ccatgaatat gagtatctac
    18001 aagtcctggt gctatttgat agcctgtata atcaataacc tctgcctgat catcaacagt
    18061 agccgtccaa tgaccaaatg tgccattatt tagctccaaa tagcctgctg gctttacctc
    18121 gttggggtaa taaaagcaat ctgctttaat atagcttgtc atcttttttc ctcccttttt
    18181 cgtttattat acgccttaat tcttattttg taaatggtat ataccagtcc ttctgttaaa
    18241 aagaaaaacc tgaatactat ttcaagtttt cccttttatt agagctgtcc tgaaagtact
    18301 ttctcagcta gatttagggc gtggtcagtg atacgtgtgt aatgagatat aatgtcaata
    18361 aaattaatcc ctgcctgtgc tgtgcattcg ccacgattga ggcgttcgat gtgtgtttta
    18421 cgcaattgac gctctttttg ctcaatcgtc ctatgacgct caacaataga ctgggctaga
    18481 gccttgtcac tatccacaat cgccctaatc gcatctaaag ttaaacagtg ggtcaggtga
    18541 tacatttctg ttaattcacc acgtgcagct gctgaaaagt caatctgctt tgctgtaatc
    18601 ccctcaatga gagtcgccaa cgactcagag tggtcaccaa ttcgctccaa atcacgagac
    18661 gaatccaaca gacctgctaa aacctcattt tcactaggac taagggcttc attggaaata
    18721 tcaacaaggt aagtggtcag ctcctcatca atcgtattga ccgccttctc atatcgcctc
    18781 accttttcgc caaacctgtc ctctgctgtc ataatgtagc tataagaggc ctcaaaggcc
    18841 tgaatagcat aggaagccag atgtaccaat tccttatggg catttcccaa ggcaatagaa
    18901 ggagcctgag tgatcaataa gcgatccaga tacaaggctt cgtatttgac gatttcgtct
    18961 tcacctggaa ttaaggttgt cacaagcttt gccagagtgc tgataaaagg aagcagcaac
    19021 agggtatttg tgatgttaaa ggtcccatgt gaaaaggcaa tggtcatctc aggtgacagg
    19081 gctaaaacag actgaagcca tagcataaag gaggtaaatg gcatcagcaa aatcataaag
    19141 atgattgttc caataacatt aaaaagaata tgagcagcag caacacgctt agctgcaata
    19201 ttagagccaa tagctgccaa aaccgctgtg atacaggtac caatgttaga gccaagcaaa
    19261 ataggaatag caccctgcag ggtcaataga ccgcccgaaa aaagcccctg taaaatacca
    19321 atgatggccg ctgaggattg aatcagcatg gtcaatgctg tcccgataaa aacaccctga
    19381 aagggcttgt ctccaagcgt cgctaggtaa tgctgaaagg ctgagactga tttcaaagga
    19441 tccatcgcat cacccatgag gttgagagaa aagaaaattc ctcctacacc aaaaatgata
    19501 cgacctaggt tattgagttt tttatttgac gtgaaaaaga gacaggctgc tccaataaaa
    19561 atcatgggca gggcgtaatc tcccagctta aaaccaatca aaaaggaggt cactgttgtt
    19621 ccaatgttgg cccccatgac aataccaatc gcctgctgta gggttaaaag gcctgcagat
    19681 actaggccaa ctgtaatcac cgtcacaccc gagctagact gaatcaaagc agacatagct
    19741 attccaacca agataccaaa gaaggggttg cttgtgtact tgtcaatgta atacctaagc
    19801 ttatcacctg cggcctgctg caagccgtct cccatgtatt tgatactgaa aagaaaaaga
    19861 cctagacccc caaaaaaatg aaacgcaatg tcttgccaat ttaccgacac aatattgtcc
    19921 tcactcgctt atttattctc ttctatttta atgtatttat tcagttatca caagggtttt
    19981 ttaatccttt taaatagtgc tcatttagaa cctattttag agccctagtc ctcttttcat
    20041 tttcctatat tcagggtata atagtgctac tcaagcgaca atgatttcaa aggagatacc
    20101 atgagaaaac cgacaaaaga gacccactac ctcatcatta gcttgcttac tattgccatt
    20161 gcaggagggg cctaccttat gtttagtagc ctctctccaa agccagctgc cattaccacc
    20221 caatctaagg gctatgagct gttaactaag gctcaagcat tagtcaagga ggccgaagac
    20281 aacccaacta aagaagctat cgcaaaggct caaaaggcaa ttaatcagct aaaaaagacc
    20341 cagtctaagg aggaattaca ggctcgacta acagctgtca gcttaaagca caatcaagaa
    20401 gacgttgcta tcaaggtcct aaaggcagcc gaggacaatc caagctctga gcttaaggag
    20461 gctgcacaaa aagccattag taagctctct gatgaggcta aaaaagctgc cttacaggct
    20521 agacttgacg ctattggact ttcaaagcct agcactgcac agcctgagac tgcaacacca
    20581 gcagcagaga aaaatatagc accagctcct gcgactccac acataaagca taccacaccg
    20641 tcttctgggg gaacgacacc agcacctaac cctaaaccta gtcctaagcc taaccctcag
    20701 cctagtccta gccctagtcc tagtccagct ccagagaccc cagagccaac acctaaccct
    20761 agccctcagc caaatcctca accagagacc aatacaccta gtcctcaacc acctgcaaca
    20821 gagcaaaccg aaaacactgc tccagcagga caaggctaag aaaggacagc tagagctgcg
    20881 gaagtcatgc tttcgtgcca ctagagaaaa taatagccat aaaaacagga cttgacatta
    20941 ctgcggtgat tccaaaaggt tagaccaaaa ttctaacgat tggggatcag tagatagggc
    21001 taatagccaa ttataccaag agcagttcca ataaaagagc agctcataaa ggttaaagcc
    21061 ctctaagctg caaaaaagct gggcccaagc ggctccagct ttttttactc ttttgagggg
    21121 gccattaatc aagcaagcag gcttgaacaa aaaaggggta gcaaaaaacg tcagaagatc
    21181 tctatcttac catctctact aatcaaacca cctcagtaag catcactacc agccgactag
    21241 cagtatgata tcttttaagc tagactgccc caaatgctta ggggcttctg tctatctttt
    21301 ttcacgatag ctagcttgaa atcagcttaa tagccattaa taggcaagag gtcgtagctc
    21361 tgaactaaca gctacctgtc caccagacaa gcagctattt ttgatgcttc tgctgaccag
    21421 ctaagttcgc aagccttctc taaaagggtc tgctagatag ctactagctc tattaccagt
    21481 tgtacttatc aacattttct tttgttacaa ggtagatagg agatactgtt tccttgtcaa
    21541 tagccttacc ctgatagtgg tcaacagctg cttgaatggc aatctcaccc atcttggccg
    21601 gctgttgagc aatagtggct gtgagatcac ctttttcaat agcctgatga gcatctggct
    21661 gaccatcaat accaacaata aggacatttt tcagaccagc agccttcaca gcctgagcag
    21721 ctcctagcgc catttcatca ttttgagcaa aaataacttg aacatcttta ttagcctgta
    21781 tcatgttttg agctgtatta agagcttttg cacgatcaaa gcctgctgac tgactagaca
    21841 aaactgtcaa gtgttctttt gcaatgctat taaagccatt gcctctatca acagtagctg
    21901 aagctcctgg aacacctgac aattcaaaag tcttggcctt atcaccaagc tttttgacaa
    21961 taaaatcagc tgccatttta cctgcttcta cgttgtcaga agcaacggtt gtcaagacct
    22021 caccgccatt gctgcctcgg tcaatcaaga tgactgggat atgagcagta tttgccgcct
    22081 taataacggg gacaatcgca tctgaatcaa ctggattgat gagaagggca tccacccgtt
    22141 gactgataaa gttttgcaca tcatctgctt gacgagcagc atcgtcttga gcgtctgcaa
    22201 ccttgatagc gacaccagtt ttcttggcag ccttatcaag accgtccttc atggccacaa
    22261 aataagggtt gttagttgtc gaaatggaaa ctccgagctt caaatccttg gcttcctttt
    22321 tagtggtctc tttggttgat tctgatgatg acccacctag accagtcttg ccacaagcac
    22381 caagtacaag caccattgag agaataaggg ctaaaaagcc tagtttttta ccaaatgtca
    22441 tttgttagcc tccttttatt ttgctacttt aaaacgatca agtaagacag caatcagaat
    22501 aacgatcccc ttgacaacct gctgccagaa tgcagacaca ccaataatat tcaaaccatt
    22561 gtttagcaca ccaatgatca aagcaccaat caaggttccc caaatacggc ccttacctcc
    22621 tgagagagag gtccctccca agacaaccgc agcaatagcg tccatttcat agctagcacc
    22681 cgctgttggc tgggctgagc taaggcgtga tgtgataatc aatccagata gcgatgccat
    22741 catgcctgaa atggtataaa taatgatttt gaccttattc agcttaatgc ctgagatata
    22801 cgctgctttt tcatttcctc ccagtgcgta gacagcttta ccaaaggctg ttttatgtag
    22861 caagatagcc aatatcacaa aaacaagaaa catgagaatc acaggaaagg gaatcccaac
    22921 aatatagccc tgtcccaaaa attggaaaag aaagctatca ctaagtccct ttgtcactgg
    22981 atttccattg gtataaacca aggtagctcc acgaaaaatc gtcatagtgg ccaaggtgac
    23041 aataaagggt gctaatttcc cataagcaat cagtaagcca tttagcatgc caaagagccc
    23101 acccaagcaa atggctagca caattgcgac aggaacagga aggccaccac caatcaagcc
    23161 tgctgcaagt gcacttgata aagccaaact tgatccgaca gacaggtcta tcccacctgt
    23221 tagaatcaca aaggtcatgc caaaggcaat aaacccatta gctgttacct gtagtaataa
    23281 attcaataaa ttgttagtgg ttaaaaagct tggattgata atggttatca cgatcatcaa
    23341 gcccaccagc gctatcagag ttgttaactc tgacatgtat ttcatagcct gcttcacctt
    23401 acttacctcc tgttgctagc tgcattacct tttcttgagt ggcttctcct cgactgagtt
    23461 ctccagtgat tctcccttca tgcataacta cgatccgatc actaactcca agaacctctg
    23521 gcaaatcaga ggagactagt aaaatcggaa cacctctctc agctaactca ttcattagct
    23581 gataaatctc acgtttggca ccaacatcaa cacctctggt tggctcatct aaaatcagca
    23641 ccttaggtgc aatgccaatc catttagcaa gaaccacctt ctgctgatta cctccagaga
    23701 ggttgccaac aaccatctct ggccttcctg atttgattcg caggcggtca atcatttttt
    23761 gaacaaaatc acgactggtc ttgtcatcaa aaaagccatt cttgctaaag tctttgtggc
    23821 ttggaagggt catattgtcc ttgatggaaa aatcaagaat taacccctcc tccttacgat
    23881 cctctgttaa aaagccaata cctgccctga ttgcctgtac cggattagtc acctgaatgt
    23941 cttgaccatt aagtctgatt cgtccagctg tcctcttatc tagaccaaag attgctctca
    24001 tcacttctgt ccgaccagca cccatcaagc ctgaaaaacc aagaatttca ccccttcgaa
    24061 cctgaaatga aatgtccttg aagcactcac cagataagtt ctccacttca aagaccagct
    24121 ctccaagctc agctgctttt gctgggtagt aatcatcaat gtcacgaccg accatttttt
    24181 tgaccagctc agctgggtta gtctcagctg ttggctttgt gtcaacaaca atgccatcac
    24241 gcatcacagt gatcagatct gtcaccctaa aaatctcctc catccggtga gagatataaa
    24301 caatgcctac ccctgctttt ttcaagctgg ctatcatttg aaaaagactt tctgtctcac
    24361 gatctgttaa ggcggctgtg ggctcgtcca tgaccaataa agacacctct gacaacaggc
    24421 tcttggcaat ctcaatcatc tgctgctgac caacagacaa gctcccaatc ggtaaatcaa
    24481 gtggaataga aatccccaag cggtcaaagg cacgctttgc cttttctttc attgcttttt
    24541 ggtctaaaag accaaaggct cccttgattt cacgtccaag aaagaggttg tcaagcaccg
    24601 tcatatcagg ccaggtgttc atctcctggt gaataaagct aatcccaaat gcctctgctt
    24661 cttgaggatt ggagaattgc ttttcaacac catcaatgac aatggttcct gagctagctg
    24721 gaaaaagccc agttagaata ttcatcagag tagattttcc tgcaccattt tctcccatta
    24781 gagcatgaac ttggcctgaa tgcagcacca gatctatttt ttctagcacc ttgttggtcc
    24841 caaaggattt agaaatggca gtcatttcaa ttttcatggt tctacctccc ttctaaatag
    24901 tgactcctga ttgtaaaatg atgtttgaat aaggtgtatc ctctcctgtt cggataactg
    24961 ccttaacgga tttattaagc gctttcaatt cttcgtgact gacatattca acagctactg
    25021 tatcatctaa ttgtgtcaaa atagctgcta gctgatctgg attggctgtc tttatttcct
    25081 cagcaagaat caccttctca atcaccacat gctcaagata catgcctaac acgtcctgaa
    25141 aacttggcag accacgctta agtgccagat caatcttcgg gactcctaca ggaaccggca
    25201 gccccaaatc tccaatgcag acacgatcag tatgtcctaa atcggcagcc agcttagcta
    25261 catcgctatt taaaatccca tgctttttca tatgcttcat gctccttcat ttcttctagc
    25321 cttggcatgc ccccttgggc accaaattgt tggacagata ggtgagaagc caaagtcgca
    25381 aagcgtaagg ctgccgctgt atttagccca tgtgagatcg caagaccaaa ggcaccatta
    25441 aaagtatcac ctgctccagt ggtatcaacc gcctctgcct tgatagctgg aatcacatga
    25501 atagccttac catcacaata agcagctccc ctaatcccga gtgtcacgat tagcttgttg
    25561 ggataggtcc ttagagcctc ttcaaggctc agctctggga atagatcctg acattcatgc
    25621 tcatttgggg taacgtagtc cacaaaagtc aacaggtcta agtctgtttc acgagctggt
    25681 gcaggattgt agaggacctt gatgccacgc tcatgacaat aacgagcaat agccagatta
    25741 gcctcatggg gaatctcatt ttgcagaatc accaggtctg ctgccgctaa cacctcccac
    25801 tccgcctgcc atgtcctggt atctacttga ccattagccc ccgggcaata aataatgcga
    25861 ttatcatgat tgaaaatggt aatctgggca attccactag ataatggtac cgttcccaca
    25921 tactccacag aaacaccatt ctttttgagg ttgtcaagca agagtggccc aaaggaatcc
    25981 tgcccaacag ctcctaacat ggtaattcta tcactgtcta agctcagccg tcctacagcg
    26041 acagcctgat tggctccttt accaccagga accatagaaa aggcttctcc aaagaccgtt
    26101 tctccctcct tagcaatccg cttagtttcc atgacaaggt ccatagaaat gctaccaata
    26161 atcacaatat tactcatgct ttctccttat tgtttcgcgt tccacatagt gaacgggtaa
    26221 ttttatgcgc ttttcatcaa tcggaagctg gttagtaatc tgataaacca attcagcggc
    26281 cttatagccc agcaagtaag aggattgatg aatggttgaa agtgatggat aaataaactg
    26341 actcatcaaa atatcatcgt agcccatcac ctgaacatct tctggaatcc ttttaccaca
    26401 ggaatgaagc tcatgaatgt aagcaatggc atggatatct gacggtgcaa tgacactatc
    26461 caaatctgga aaatcagtca gagcctgctt ggcttcgtct tgaatggctt caaagtcaaa
    26521 gctactacta tcgcaaatag acgtccgaac accagcctcc tgaaggtagg ctaggctagc
    26581 ttcaaaacgc tcgtgcaggt tttcagcatc atctagcggc cctcggataa gaaggatatg
    26641 attggcaccc gactcacaaa ccttctgggc agccagtcgc ccgccctctt cgttgtctga
    26701 aaagacacca aattgggttt cttgattgac ccggtcaacc accacaattg gaatgtcaat
    26761 ctccgggtga gtcttggtaa agtcatgtgt cgtaataatg ccagccgcat tactttgtcg
    26821 catgacatta agatactcct cctccaagac tggattgtct gagagatttc ccagcatgac
    26881 tcggtagccc ttttccttca aaaaggtctc agcccctcta gccaagcgag ggaaaaaagg
    26941 gttagaaata tccggcagaa gtaagcccac cagctggttt ttcttggttt ttaaggattg
    27001 agcagacaga tttggactgt agtgcagctt ttcaatagct gccttaatcc tatctcttgc
    27061 ctcctcactg acatagcctt tttgtgaaat gtagcgtgaa actgttgact ttgataaacc
    27121 agcttccttg gctacctgtt taattgtcgc cataagtctt atcaccttct ttttatggaa
    27181 ccgttctcat attgttattg taaccgtttt ctaaaacgct gtcaatacct tttacccatt
    27241 ttattttgtg actcttaaga acagttaaaa aatcaagcaa ccaaaatacc ccaagaatta
    27301 gacaagacct ctaaccttgg ggtgcaaagc tacacgagct aggttttaaa cactgacata
    27361 acaagcaact gcccagacag gctcagctac cagccacatt tgctgctttt ggattaatag
    27421 gccttaaacc tcatagccca tgagaagccc ttcagcttct gcatagaagc tgcataggcc
    27481 tgaggctggg cttgtttgaa tctctgcttc tgggtaaatc gctctaattt tttctgcaat
    27541 ctgttcacag atcttagggt ttttggcatg ggagataaag actcgccctc ctttatagcc
    27601 tgccttttga atctcttcta aaacagctga cactgccttt ttttgacctc tggccttttg
    27661 aagcagctca agcgttcctt ccttacttgc ctgtcctacc attctgatgt ttaataagcc
    27721 aatcacctta ccaatgagct tattcagacg gccattttta accagattat caaccttggc
    27781 caacacaaaa acaagcctgg ttttttcctg ataagctgta attttctcaa caacctcatc
    27841 aaaagaaagc ccctgattga tcaaccgctc tagctctaac acaatcaaat ccatctcacc
    27901 acctgctgac aaagagtcaa tcacatggat attggcattc ggattttcct caagcaagtc
    27961 attttgagcc aatctagcac tattgtgact gcctgagagc gtaccggtaa tggtaatggc
    28021 aatgacatta tctgcccccc tgtaggcttg taaaaaagca tcaggacttg ggcagcttga
    28081 ggttgctggc ttagaggact gatacatagt ctccatcatt tgatcaatat ctagaccatc
    28141 atcatctcta aaaatatctg aaccaatctg tagggttagc ggcacacgct caaagcacag
    28201 gtgattggat tggcttttta gggctctaat atcgcatcct gaatccgata caattttcca
    28261 ggtcattcgt tttcctcttt tccttcatag tctgttttgg ttgacaaagt aagcattttc
    28321 ccataaaatt atatcatcac tagctaggct tttgctagct aaaatacgtc agatgtaaca
    28381 cttgaaaggt atttgtaatg gctggtaaac caatttctaa acagtccctt caaaatttag
    28441 cccactgcaa tcaggagtcc agacggttaa cacgagaagc tattgaaatt gctctgctta
    28501 gcttactgga aaagaagccc ttgggacaca ttaccatttc agaattggta gctagagctg
    28561 gggtttcaag aaatgctttt taccgcaatt acagctcaaa ggaggatatt cttgagtgtc
    28621 tgttgacttc tgttatcaga cgtatctttc gtggactgaa ggcctttgac ttaaagacac
    28681 aagcctatca ggcatggctt tatctgttta cagaggccaa aaaagaagcg acgctgctta
    28741 gtattatctt taaccatcac ctgcagcagc tcttgactca gatggttact aagcgcttga
    28801 gggcctacca aaaatggcag gaaaaaaagc tgtctcatta cgcattgctc ttttggagca
    28861 acgctatcgt ctcagtcctc tccaattgga tttctgatga tatggttgtt cctgctgagg
    28921 agatggctgc tatggggctg cccttattag cctagttgtc tctagatcac ctatagctcc
    28981 tagacaactt cccaagaaac caagcttgca ccatcagaca ggacgcttgg ctggcttgac
    29041 ttaagcactg gcactgccta ccaagatatg tactagccct actacaggca aggtgtgact
    29101 tgtcgctcgc tgttgtgcag aggcttaaag gctcttactt ttagccaagc cataaaaaaa
    29161 agactgaaga gactgacgag attagcctgt tcttcaatcc agaacctcct ttgttggagg
    29221 ttttttcgtg ttttattttt cagtcgatct cacacaccta ggcttgtggt gttccaagac
    29281 agctcagctc tggtcaacac ctctaaaact gagcttatca tctctagctt ttggaggcct
    29341 ttttttgatg ggctggttta attgagctta tgagtccttt ggtaaggcca attgataaat
    29401 ggcatgggcc acacctgctt gatcattgga gaggcttacc ttgtcagcga cctttttaat
    29461 tgcctcatca gcgtttccca tagcgacacc taagccagca taggctaaca tttcaagatc
    29521 atttgctgca tctccaatag ccatcacttg gtctggacgc agcctcagat cagcggttaa
    29581 ttcttttagg gcagaggcct tggtcacaca ctccggcatt acctctagga ttgtctcttg
    29641 actgcggacc acactaaagc ttgcgctgag tttttctcta acaagagctt caaaagtatc
    29701 tagggcagcc ttttctccca tgtacatggc ctgaaatatg atttgactgc tgttggataa
    29761 ctgagatagg ctagtagcct ttacctttgt aaaaaccaaa tcaccatcag cctgaaccat
    29821 atctggaacc ttgctgtcta tcacaagata atcacgctct ccagtcaggg tgagataaat
    29881 atctgaaaaa ggctgtgaca gctggtaaag gtgctcaata gctgaaaagg tcaggctttg
    29941 ataatgcagt agctcccagc ttgggctcct ataggtgctg cagccattgt ttaaaataag
    30001 gtactcctca tcatcactca agcctaattg ctcaaaatac ggccttgtcc cagactgggg
    30061 gcggcctgtg cagagaacaa cctttatccc ctctcgtgca gctgcttgga tagccttgat
    30121 attctctttt ggaatgtgct ttttgctatc cagcagggta ccgtctaaat caattgctat
    30181 aagctgaatc atcgtatcag tcctctttcc attttatctt aggtaggtgc cattgtcttt
    30241 tgttgccaat catacgcatg actgtcaaca aaacaaccag caggtagcat tcaacatttg
    30301 aagtggccag cttaaaataa agcacaagtg ctgctatgat agaccagcca gcataaatct
    30361 cacttctaag aacagttggc ttacggcctg ccaggacatc tctgacaaca ccaccgcctg
    30421 ctcctgtaag aaccgctgct acaataacag cacttaaagg ctgggccagt cgaacagcat
    30481 gtaaagcccc ctgaacacta aaggctgcaa gcccaatagc atcagttagc accgctgctc
    30541 tgacccagcc cttagccacc agcctaggaa acagcatgat cagaataata gctataaaag
    30601 cgcaggcaaa ttctggtctt tgtccccata aggcttcaat aggcagtccg atcaaggtat
    30661 ttctaatagc cccaccacca aaggctgtga caaagcctag aataaaaatc cccagaacat
    30721 caaactcctc ctccatagcg acaatagcgc cggacaaggc aaaggctatc gttccaataa
    30781 tgcttaaaag ctcccacata tcaattgtca taactcacct aatgcttcct aatcccctat
    30841 tagtctacca tctttttaat caaaatataa gtcaaaataa gagcaaggtc ctcaaaaatc
    30901 ctactgatga cctgtttttg tttgcaccaa agatttagcc cctatatagg cttctggtag
    30961 caggatttag gagcgatagc ttgccaaatc cacagccttg ttattttcca tgagaaaggg
    31021 ttctgctgac gtcttggttt gataggtctt gtatttatga tagaggtatt ggtagcaatc
    31081 ctgtttttga tcgaagagaa ttgcctgata gggctcttgg aaggacaatt tctcaacaaa
    31141 cagatgcttg cccttgtgct ctactaaaac acccacgtga ccaataaaca aataatcacc
    31201 atctagctga tcgtgaatca caacagacag cattttagcc tgatcattga aggtaactgc
    31261 tgagagatgt tcctgcatat gcttagcatg cacctgaata tccttggtgg cttctgtttt
    31321 cacccttgaa aagagctgct taaagcgctc tgtctctgcc tgcgtaaaga gctgtcttgt
    31381 ggtaatagcg tcctcgtcca taaataaaag cgtgtcatca ctgctgattg gcttgatggc
    31441 tatcgtgtcc tttaacagca taaaggtgtt gatccggcaa ttcgtaccaa taaagtcacc
    31501 ttgcttttgc aaccacagct catcaattgc taccacatca tagtcaggct gcttctgata
    31561 ggtaaaggcc cctgtcaagc ctgttttgcc aactaggcta ttatattctt gtacaccagc
    31621 cataaaggca ttgacattag cttccttcag ctgatgtgat agggcagccc tgacctcctg
    31681 ctggctctct gcactgttca tgttagatag gaaaagacgt ctcttcttag cctgtggctc
    31741 tttttgctcc tgcttgggct gatcagactg gtgagaggcc tgacaagccc caagagctgc
    31801 tgtagcaagg attagcaaag atatcattac ttttttcatc ataacctcct ttttaatgag
    31861 tcattcaagc tggtactccc catcatcacc aaatgagatt atcagcagct ggcagctaat
    31921 acgaggttgc tacaacccac ttgctatctc tttatgtcat gacctcatcg ttaccagtat
    31981 agcataaaaa cgaaaagcac cagttcttga agccttgcag ctctttttgc cagtgctttt
    32041 cgttaggaga ttacattgaa atggtttttg tggcagctag ctgctgatac caataagcgc
    32101 tttttttagg gtaacgcttt tgggtttcaa aatcaacata gaagagccca taacgcttat
    32161 catagccatt tgaccaagaa aagacgtcca tcaaggacca gataaaatag cccttaacat
    32221 tagccccagc accgatagcg tctgcaatca ccgccaaatg ctgcttgatg taatcaattc
    32281 tagcgtcatc atcaatcctg ccatcaatac aggtatcctt gtagccaagg ccattttcag
    32341 tgatataaat ctttttatag cctggatagt ctgccttgat ccgcatgatt tgatcgtaaa
    32401 gcccctgtgg atagatcatc caatcccagt ctgtacgcgg cacatcaaca tcaaatatgc
    32461 gttgaccaac cccctttatc tgatatttgg agccgccttt ttctcccttg ccattatgaa
    32521 tgatttcggt ctcaccatca aaggcacgca gccaatcact catgtagtaa ttaatcccaa
    32581 gaaaatcgtt taaatccttg gctgcctgta atagctcaaa atcttctggt cttagatcaa
    32641 ggctgccgcc attttcagca agaatatgct taacaccagc cattgttttt tctgagtatc
    32701 gcccaagata agtggcatct aggataaatt tattgtgaat aatatcatct agctctgcag
    32761 ctaggacatc tgctggattg gtaggatcta gagggtattt cgttggcagc gcatgaacaa
    32821 taccaatttc cccaggataa gcctgttcct tgtagtgcac aagagcacgc gcgtgagcta
    32881 gcatcatgtt gtgatgtgat tgaaatacct tggccaagtc ataactaatg ccaggaggaa
    32941 atttcccgac caaatactgt ccatcaccaa tcggtccaat ctcattaaag gttgtccaat
    33001 agctcacctc tggaaattcc ttgaagcaat aagcagcata agcaacaaag tgatcaatat
    33061 tttctcgatt gagaaagtct cccctcgaat gaagcgcttc tggcgtgtca aaatgatgca
    33121 gggtcacaaa gggctcaaca tggtgcttgt gacattcagc aaaaaggctg tgataaaagg
    33181 cgacaccctt agcattaacc tcgccaaagc cctctggaaa aatccgcgac caagcaatgg
    33241 aaatgcgaat accattaatc ccaaattgct cagccaaggc caaatcaaca ggatactgat
    33301 gataaaaatc actcgctggc tctgctgtgt accaataatt gtccttcaaa taacgatccc
    33361 aagccactgc tcccttaccg tctattgttg tggcaccctc agcctgataa gctgctgtag
    33421 caccaccaaa aatgaaatcg tcaggtaatc gtttgatcat gatgacctcc tagttttcta
    33481 gctctcgttg cacaaaagcc aaggcagcct gaccatcacg cgtcagtctg atgtattctg
    33541 ctccttctgt cttggccagc ttaatgccta gcttgtctgt ctctagcttg atgtcctcat
    33601 aattagaagc aacctgcgga gctaggataa ccagctgata ttgcgacaat atctccctgt
    33661 gagcaccgta gctgcccgca gcagccttga ttggtgcttg atatttcttg gctgcctttg
    33721 tcaacgcatt ggctaagagg ccacttgttc caccacctgc acaaagcaca aggatattag
    33781 cttctgcggt gattggttgg tgcttttgaa gaatagcctg cgctttttta gtatcaaagc
    33841 tagccgctac cttatctgtt agggattgat gagaggtatt tccagctatc tcctcagcaa
    33901 ggatttgctc atcatagacc tttaagaaag gataataaat caaaacatca acagcaatca
    33961 acacagcagc aaggacaaag gatagcacct gaaggttcgt tcctaatacc aagccaagcg
    34021 gagctggcgt tgtccaaggc aggttggctg taaagctatt cattcccagg acatcaatga
    34081 agaacttgaa gatccaaaca ttaacaatcg gtgtcaaaat aaaaggaata aagaaaatcg
    34141 gatttaacac cagcggagca ccaaagagta tcggctcatt aaccccaaag aacgtaggca
    34201 caacagaagc acgtccaata gctcggttgc gttttgattt ggttagccac ataaacataa
    34261 atggcacaac aagagtggca cccgtaccgc ccattgtcac aataaacatt tgcgtaccag
    34321 aggtgagaat cttatcagca tgctggcctg cctgcaagag gttgagattg acctcagcat
    34381 tggcataggt aatcgctgca attgccggct caacaatgga tggaccatga atccccacaa
    34441 accaaaagaa ggcataggct ccaaaaataa gcgtgattcc caaataccca tctgcagcct
    34501 gaaacaatgg tgctaataag gcaccgatgg actcagcaac attaacccct aaggtctgct
    34561 tcactatcag ctgcacaaga taaagtaaaa caatagataa ggtaaatggg atcaagtcct
    34621 taaatacctg tgaaatgtta ggcggtacct catcaggcat gcgaatggtc acatgatttt
    34681 tgacacaaag cttataaatg gttaccgtca caaaggcaga aataaaggca gtcaaaagtc
    34741 cctttgttcc catgaagcct gttagaagac cgccttcttt tgcaggatca gcagccatta
    34801 gtagaaagcc aaccattgca gcaagcatgg ttgataaata attcatctga ttggtagctt
    34861 ctagctgacg attgatcgag tcagtcaagg ccttggctgt tgttccggca acaaaaaagc
    34921 caagaatacc cattgagtag ctataaggca gcatcagtaa ggcttcaaca gacttactcc
    34981 aatgaaagcc ccaagcattt gggacataag ccagtaaaat aaagatactt gaaaacaaaa
    35041 tgaccggcat acctgcaata aaaccatcac gaatggcacg taggtaaatg tttcgagaaa
    35101 tcctctcaaa taaaggcttt cttttttcaa tgtgttcaat tagcttgttc atatcttatc
    35161 ctctcttgta aagctcaata aggtgcttca tcatatcctg cagcagcaga gtcgtcatca
    35221 aatggtcctg cccatgcatc aaggtaacac taaaggcaat atctgagcct gttgcttcct
    35281 cctgcaatag actcgtttgc gccttatgcg cttctaaaat ggattgattg gctgattgac
    35341 aaagcgcctc tgccttgtca taatcgccct ttttagcggc ctctaaggcc tcaatcagct
    35401 tcgatctggc ctcaccagca taagcaacaa tttcaaagcc aagcatggtt atttcttctt
    35461 tggtcatttt gtctccttta tagtaagcgt tgaatatgga ttacaatgta gattttttca
    35521 gactctacca gctcttgacc tgttagatct gtcatcagct gatagatagc actgcctatc
    35581 tcataggctc ttgggtattc ctttttgatt tgctcctcca agctccccat agcatgatag
    35641 ccttgattct tacggtctag cgactggata aaataggtca agtggatcat cagtcgatca
    35701 taaaaatgac tgttagtgct tgttcgtgtg atcccattag ccagcagggc tgcttccacc
    35761 tgattaagga gctttttggt gctgctatgc tctcgttgag gactagattc ctcaccctta
    35821 gcattaataa aatgcagggc aatctttgtc acctcatcat ctggaaaggt tgtccttagc
    35881 ctctgccgaa acatctccag agcagcctgt gccatctcat attcctgacc aaattcttta
    35941 gaaatgtcag gcaagcgatt aaccgaatag gtcccctttt gcagcatatg ataagcagca
    36001 tagatatgat cggtcaacgt cacataaagg tactgctgga ccgggtaatg ataggtcaag
    36061 accaaccaat caatcacatc ataggtcact gtaatgacat ctaacggcac gtcttttagc
    36121 aagagcagta agttttccct tgcttcatca ttttttaata aaaatgtttt ttcaacggct
    36181 tcttctcgaa tcaagtctcc ttttttcttc tgaaaagcaa ttcctgcccc cataaccact
    36241 gcctgctcgt tggcagcatt cttaaccaag gcggcattgt tattcaatgg acgaatcagt
    36301 cggaacattc ctacctcctt ttttaacata aaaagaccac aaaccaatca gaaaaaagct
    36361 cccaattcgt ttgcggtctt gcctaaatca gctttagtca caatccacca tatacgtttg
    36421 tcattgtaat gctattataa ggcattatcc taaaaatgta aaccctttct ttagtgctgc
    36481 tatcacaact aaggcctcac ctagcgctaa tgcagcctca gcttcttgga aaagtcttac
    36541 catttgatta ggataggctg ttactgtcac agcaatgtcc tggcattgct tttatcatgc
    36601 ctttactagg cttcatcaag agtaagcttt gttgtccaag ggctggctgt tttctcaagc
    36661 acctgattga gacgatcaat attctgaaag ccctctgtgc gaagccattg acgcgctgcc
    36721 tcctcgccct ctgacatgta caccgctact gctcctgacc aggtagcccg accacatagc
    36781 actccattaa acctagctcc tgcctctgcc gcaaaaacca aggtctcttg aaacagacta
    36841 gctgatacac ccgcactcaa ataaatatat ggcaaatgac tagctgcctc ttggtcacga
    36901 aaggcctgca tagcctcctc tttgctgtaa acaacctcac cctctgcaaa gccctcaaca
    36961 taggccatat tgacaggaac ctctaccttt aggacatcaa ccccaaagcg ctcagctgaa
    37021 aagaccttca tggcctcatt aaccttgtgt gcctttagct tggcaaaggc tacactctga
    37081 ttgtctgtta tcgcctcatc ataggtcaac agctcaagga aaaatggtat ctcctctgcc
    37141 tgacattctg agccgatacg ctcaatatag gcctgctttt gctggttaat gtattcatct
    37201 ccatcaacat catagtaaag caagaacttc actgcgtcag ccccagcctc cttgaggcgc
    37261 ttgactgacc agtccaccag acaatctggc aggcggctag tggtggttgt gtcatagccg
    37321 gtttgttcat aggctaataa taaaccagac ttctcatcac gcaccttggt ggctggcagg
    37381 ccatattcag ggtctagcag gatagaggag gcataggggg ttagctcttc tgataccaga
    37441 gcctttagag cttcgatttg ccaaggcgca ggctctgtgt cttggtgggc tgccatcatg
    37501 cgcttcaagg caccgcgctg atcaaaggcc aaggccgaaa tgattccctt acgactgacc
    37561 ttttctaaat aagctttttt gtttcttgtt aatgtcatct tatacctcct ctacttgaat
    37621 acggtcaaat agctcatcaa aatgtgccat gttaacatga cctgttcttg tttcttgcgc
    37681 atttaacatg cctaaaacat tggctttttt cagaagcgtc tcatcgtcat ctccttctgc
    37741 caaagcccaa gcaatccctg ccacagtagc gtcaccagat ccaacaggat tgactacctc
    37801 aattttagga atggtaacac ggtaaaacct gttatgatgt ttggcaaaag ctccttgggc
    37861 accaagagaa acaataatcc attctatccc ttcaaataaa ggttgactca acagagagat
    37921 taaacgttcc tcatctaatg tgacaggttg gcctatcaaa tcctccaatt cttccaaatt
    37981 gggtttgata acagttggtt tatctttgcc agccagtacc gcttttaaag gagcaccaga
    38041 gcaatctaaa accactttgc tgccataggc tctcgccata gtaatcaagt cttgataata
    38101 gtgagcggcc agacccttag gcagactgcc tgaaaaggtt aagacatcaa actgcttagc
    38161 aataatactc atgtggttca aaaagccttc ggcctcgtcc atatcaatgt agggaccagc
    38221 ttccagaatt tccgtctgca tgccttcatg taaaacagca atacaatttc tcgtttcccc
    38281 tttgattttg aagaattggt tagaaatgcc ctgttcttgt aactgatgaa tgacaaagtc
    38341 acccagtttc ccaccaataa atcctgttgc cacaactgac tgaccagctt ctgctaacac
    38401 tctggtcaca ttcagcccct taccaccagc tgtttttgtc gttctgtcaa cacgattaac
    38461 cgtgtccaaa gtcagacgat ttagaggata ggaaatatca atggatgggt ttaaggttac
    38521 cgttaaaatc atcgcttctc cctaatcgtg gtactcgcca cgatcccatt tttccaaaaa
    38581 ctctgtaaag aagtcaggat cttcttggtt agcattatgg ctttccaaat gggctatctt
    38641 agcaattaac ttcttattct cttcggtttc cttgtattct gccttgataa aagcttcgat
    38701 aatatcacac atgagcagtt caccagtgat tttaccacca aagccaatca cattggcatt
    38761 caattcttct ttggcataaa gcgctgttgt catatcccta acaagcgctg agcgaatgcc
    38821 aggaaccttg ttgacagcat tattaatccc cacaccagtg ccacagatac agacaccaag
    38881 atcagctcgg ccattagcga cagcctcacc aacccttttc ccaaaaatcg ggtaatgggt
    38941 gcgggtatgg tcataggtcc cacagtcaat cacctcatag ccctttgatt tcaaaaaatc
    39001 tgaaacagcc attttttcat tcgtcacaat atggtcacag ccaatagcaa ttttcatgat
    39061 atcctccctt cgttaagcca ttttattgag catgtctaca cgtatttgat ggcgtccgcc
    39121 atcgtagcta ccgaccacaa aggccttagc aatgtttttt gccagctcct caccaacaat
    39181 ccttgcacca agggtcatca tacgagcatt attgtggcca cgtgtcatgt aggcagagcg
    39241 ctcatcagaa acctctgctg ctatcatgcc ttttagcttg gtcgccacca taaatgggcc
    39301 tgcaccataa gcatcgacca taataccaag attagtgtcc ttatcattga ccgcctgagc
    39361 aactgccaag gtattgtcaa taaaatcctt atctatgtct gtcacgtctg tcacatcaaa
    39421 gccttcctgc tgaagaaagc ttttaagaac ctcttttaac tcattgccat gtgcatctgc
    39481 acccaaaata atagccatca catctccttt acatttgatt ggtgtttttt gttcgatatt
    39541 gtttgttaat cgtttacaag attattttat attaaaaaca aacatttatc aacatatttt
    39601 ttgatatttt tgttttattt tttttaattt tgttgcttat tgaaaaaaac gatgctttgt
    39661 gctatcatta actaatcata ttccagagaa ggagagcggt catgcttaag cgtgagagac
    39721 tgttaaaaat cattgaaaag gtaaacgcca acggtattat tacggttcac gatatcattg
    39781 aacaactaaa ggtctcagat atgacagcca gacgagattt agatgagcta gaaaaagccg
    39841 gaaaattagt ccgcattcat ggtggtgccc aaagcattgc tatgcctcaa aagctcgagc
    39901 ggtcaaatac tgagaaatta accgtacaaa ttgaagaaaa aaaagaaatt gctaggtatg
    39961 ccagccagct cgttaacgat ggtgagacca tttttatagg ccctggaaca accttagaat
    40021 gcttggctga ggctctgatt aatcgtcata tacggattat caccaacagt ctgcctgtct
    40081 ttaatatcct tcataaaagt gaatccgttg atctcattct cattggtggt gagtaccgag
    40141 ccatcacagg tgcctttgtt ggtagtctag ccagtcaaac catcttatcc ttgaagtttg
    40201 ccaaggcctt catcagctgc aacggtattt ataaaaatga cattgccacc tacagtgaaa
    40261 acgaaggggt tattcagcgc ctagcctgtg acaatgccat cgaaaaatac ctgctcgctg
    40321 acaaccaaaa gtttaacgcc tatgactttt acagctttta tcaccttgac aatatcgacg
    40381 ccattatcac tgactccaag attagtgaca gcgttaagga gcgttaccgc caatttgcca
    40441 agctcttaat cgcaaggcca gctgacaatc aggtcagcag ctagacagcc tgcctctcta
    40501 tctgtttcca ccctgagtcc agcaggtaaa caaagctatc aaacgaaata gcatcataaa
    40561 agcgcatgaa gccactaata ttgcaatggg gcttcatgcc ttttttaacc tatcacacgt
    40621 taagcaaagc aaaaagaggc taggacaaaa atccttcctc ttttaaaatc gtcaaactat
    40681 agagttgatt ggagggctct tagccctcat ttttcaagcg atgtggcctt tttaatcagc
    40741 tgctcgaggg tggataacct aatcaacatc gccaggtcat gacgattgaa tggttattcc
    40801 actctttttc tacgctgagg gctgtgaaag ggctcatacg acagcttagc cgctttctaa
    40861 cagctattta cctacctcac ctcttaacga gcagacagcc taaatggtat agtccagctg
    40921 atcaagactc tttttatggt caaggtcaat atcaagaaag gtcatctgct tgatattgat
    40981 aaggctggct acaattgata ccggaaaagc aaccaccgct tgattgaaga gactaatatt
    41041 actattgaca atgcgttttg ctgctgccaa ggctgcattt tccttagcaa tctcattttg
    41101 taggctcaaa aactgctcag aggagcgcat ttccggataa gcctctccta cagcaaaaac
    41161 ctcattcaag gcctgctcct gtgccctcat cacatcattt gtttcctcca aggaaagtcc
    41221 ctgacgcagc ttcacgagtt cagtaaagac cttttcctca tgcttggcat aggacttagc
    41281 gatttttagc atttccgaaa tggtatcata ccttttctca agagcaatat cgacatttcg
    41341 tttagactcc tcaataacga ttcgatacct ttctaatttg tttctcactc caataagcca
    41401 tagtatagtc atgcaaagaa taagtgttaa catagatgac gtcactgaca taaaaaagcc
    41461 tccttaaagc tgatgattta gtgtatccaa caagcggtac atcttaacaa gcttgtcttg
    41521 aatgttttca tattcgctac ttaacgctag cttttcaata gcacctctag agctaggggt
    41581 tttcaagagc tgttgaccgg aatagaagga cacaacaaca gtatcaccat tcatataaac
    41641 tgctacaggc atctcctctc tccattcatc aagcactgcc agcatataag gatttaagag
    41701 cattctagcg cttaattcat ctgtgcagta cacattgtac gtttcattaa agcgaatgtc
    41761 ctccatttcc agctgcacct caccctttag cttagccttg tagccactat ggaccttttc
    41821 tctgcccaaa aagccctttt gagtcggcac aattctaata taacccttga tagctgtatg
    41881 atatttagcc agcagcacct gtccgttaaa atcagtgacc cgatgccagt tatcatcctc
    41941 attttcctca tggtaggcat aaagattgca aaattctgtc tgcatgtcat ctccaaaaat
    42001 aatatggcaa ttactgtcat accatctgga ggacggtgtt gcaagcttta gtaaggagag
    42061 ctcaatccct gaatagtaat ctatcttgac atctggcagg gcctcttgta aaacaggcag
    42121 caaaaagtga tccacatagg agagctcatt tgctgttttg aatgttttca gccgcggcca
    42181 aaccaagccc cccacaaaga taatgagaaa taaggcaaga gatcggtcaa ccatgccata
    42241 caagatgatt gcgcctatca ccattgccag ccagcccaga ttattctttc tagcatttcc
    42301 actcatctcg cttttaattt gctccagctt ttggtgatgc tcaggcgaag cttctatagc
    42361 tctaatcttc tccaaaacaa taggatctgt caatcgctta gtattttcgt tcatctcact
    42421 tactccagat acttctccat cagcagcgct cagctgctct tgataacacc agtcacttta
    42481 tgcttttgct taacctataa atgacaattg agttacagct aatttataat attataccat
    42541 ttttaaacta ttttttctat cattagattt aaatgacgct caataacaac cacataatgt
    42601 taatataggc atcattgtgc tcttttttac ctaatcatgt tgtgagcaat acccctgctt
    42661 atcagggaag ccataaaggc ctctatgaga tcaagactat cagcgccagc ccttcttttg
    42721 gagtcactat tcagcttgtt cttcgcatgc tgtctttgcc tgaccatgat tcagctgctc
    42781 tttttgattg cttgttatgc cctctttttc cgtctcatgc tgagcaagaa aaaatagcaa
    42841 acccttgctt ggtttactgc tcttctgttg atgttagtcc aaaaataagc tgggagctaa
    42901 tgacacccta ttaactcata aagcctgtta tcctttcttt gtcatagaac aattcactta
    42961 gtctattctc aaccaaaata cgaagcctgc ttaaaccgtc ttctcatatt aacagctaaa
    43021 aagtggtgtc aatatgaaga aacctatgat cggtaacaat aatagcacct ttaaatctct
    43081 cagcgataat gtaaggttat cctatacctg tcatattttt cggtgctatt tgccatatca
    43141 gcttgctata gcgcttggtg gcttctggta gccttaacca acaaacgatc tgctttttta
    43201 ttcctgctct ttgttttgct tatgcctttt gtcggcgcag gcctttagct ttactatact
    43261 gacggtaagg tcggtgagag cctttaccat tttttatgcc ttaatcgcaa agcatttaat
    43321 accactgata ttgagctaag gctcatggca aagccagcca gcattgggtt taatagaggg
    43381 ccgccaaata tgtgaagagc tcccatagca atagggatca ttaagctatt gtagataaag
    43441 gcccaaaata aattttgctt aactactctg atggtttgaa gactaagctc caagcagtca
    43501 accacatcta acaatgacga tgtcatcaga ataatatccg ctgcctcaat agcaatatcc
    43561 gtcccagagc caatcgagat accaacatcg gctaaggtca aggcaggtgc gtcattaatc
    43621 ccatcaccaa ccatcgcaac cagctgccca ctagccttca aatccgcgat aatctgggcc
    43681 ttttgagcag gcagcacctg actaaagacc tgatcaattc ccacctcatt agcaatcgct
    43741 tgagctgtga gggcattatc tcctgttagc ataaccgttt gaagacctaa atcctgcaag
    43801 gcccttatag ctgccttact gtcagccttt agcctatcag caatcagcaa taaagcacat
    43861 agctgattat ccttggcata atacactacg gtttgcccct ttaaggcagc ttgctcggca
    43921 taggtctgag cagcgcttat cgcaatcccc tgctgtgaca tcagctgact attgccaaca
    43981 gctaagcgat gctggtcaat ggatccagta acacctaagc caacaaacga ttgaaagtct
    44041 gtcaccgtta acaggtcata gtcctgatca cgtgctgcct taacaatcgc ctctcctaaa
    44101 gggtgctgcg aatactgttc taaggaagca acctcttgaa gagcctgctc tttatcagca
    44161 gcaagaggga cgatatgctg caattgagcc tttccttgcg tcaatgtgcc tgttttatca
    44221 aacacaatcg tctgcacctg ataagtcttt tctaaaatat ctcctccctt aaagagaatc
    44281 ccttgctcag ctgcacgacc tgagccaacc atgatggcag tgggagttgc tagccccaaa
    44341 gcacaaggac aagcaatgat caacacagca gtagccactg tcaaagcaaa atcaaggctt
    44401 tctctcataa caaagaacca aaaaagaaag ctcagcaggg ataagcctaa tacgataggg
    44461 acaaaaacac cagataccct atcagcaatc gcagcaatcg gagccttagt ctgctgtgca
    44521 cgctctacta gctgaatgat ttgcgctagc aacgtatcct gcccaagcct agatggctga
    44581 acctttagag ctccttggcc attgatggta ccagcaaata catgatcacc agcctgctta
    44641 tccactggta ggctctctcc tgtcagcatg gactcatcaa cagcagattg tccgtctagt
    44701 atcagcccat caatagcgac cctttcgcct ggttgaataa agcaaatatc ctcactcgtc
    44761 acctgctcta aaggaatcag ctggatctct ccttgacgaa taaccctgac atcattgacc
    44821 gttaaggaca gcagcttttg aatagcttgc gaggctcgcc cctttgtgcg gctctccaga
    44881 tagctgccaa gggtaatcag ggtcaaaata accacgacag attcaaaata aagctgatga
    44941 acaaacgagt ccattccagt cacaatctta aagaagctat aagcactgta gctaaaagca
    45001 aaactagtgg ctaatgccac aagcgaatcc atattagggt gtttctttac cagtgcctta
    45061 aagccattta catagtactg ccgattcaag aaaaggacag gcagggtcag caaaagctga
    45121 acaagaccat agcttatcgc atgcaaacga ggagataggg catcaggcag ccacaagcca
    45181 agcataggcc ccattgacag gtagaccagc ggcagactga acaaagcaga ccagacaaaa
    45241 cgataccaag tctgatgcgc ctgctcctct agacggtcca tttgtcccct cacatcagtc
    45301 tcatcaagca gctctgcctt atagcctgca tctcttacag cctgaataat ctctgctgag
    45361 gtcaacctag cagccaagta agttactgac agcttttcag ttgtcacatt aaccaccacg
    45421 tcctcaacac ctggtaattg cttaaccgcc tgttcaatcg ctagcgcaca ggaggtgcaa
    45481 tgcatgccct ctagcataaa ggtttcttta gccattaatg ttcctccttt ttctgacaat
    45541 aacattgccc cggtaagcaa tgacacaaaa catcaggtac cgcttgcgct gctttagctt
    45601 ccaataatac ttgaaagttc tgaatatcct ccaaggtcat cggggtttcc ttgagtaaag
    45661 ctagcagcag atgactatgg tgacgctgac acatgccatc aagcctctca cgtaagatcg
    45721 caagctctag cctatcctga tcaagcaagg actgataaat ataggaccgt ccctgcctat
    45781 cagcccttag ggcttttttc ttaaccagac gtccaatcaa ggtcttaacg gtggaatcag
    45841 accagtggta ttttgcatga agaatagcaa taatctcaga gctcttcatg tccccattag
    45901 cccaaacaac acgcataacc tcccattctg catcagatat cgtatccata ttgctacctc
    45961 tctttcatct acggttttat taagtatagc ttatttgttt acatttgtaa acaaataata
    46021 actaaaaaag gtctctttat gagaaacagc gtcaaaaaag gactgacagc taaagtcagc
    46081 agctagcttt taatagtctg aactttccag tcttatctga ttaactttat attgacaaaa
    46141 tgagtccttg tatattacta tatgacagta atactgtaat gattaaggag aaaacattga
    46201 cgtatcttaa aagacagcta attctactag cccttctact cacagctata ggtagccaaa
    46261 caatcgttca ggccagcacg cgatcctgga aaagctggtt tattgagcaa tatttttggc
    46321 ttaaacgaga caaaagctat tatgccgagc aggatgagaa taccttctac aactacgtca
    46381 agtcagctgg tgaaaagagc aatcaaggct ttaatctcac tcaaaatgag gtcaacggaa
    46441 cattaaagac agagtatcga gacaacatgc aggttcacag ctggaatgaa aactctacta
    46501 atccatcaaa tcaaaaggtc attctctatc tgcatggtgg ctcctaccta aacaacccga
    46561 cctcatacca tattgacatg ctcaaaacct tgtcaactag ccttgatgct aagattgtat
    46621 tgccgattta cccaaaggct ccgacctata cctatgatgt cgctatgcca agattagtta
    46681 gtctttatca ggatattcta aaaagcacta ataacaatgc taacaatatc accatcatgg
    46741 gagactctgc tggcggtggc ttggcgctgg gacttgccct agccttgaaa actgagaata
    46801 ttactcaacc taaggacatt atcctgcttt ctccttggct tgatgtcacc ttatctaatc
    46861 cagatattcc aaaatacgaa tcctctgacc ctatcttgtc tgcttggggg ctgcggatcg
    46921 tgggcgatat ctgggcacga cgtggtgaaa acaacactaa gcacccctat gttagcccta
    46981 tctatggaga tacaagcaac ctagcaccta tcaccatgtt tgttggaact cacgaaatct
    47041 tttacccaga catcaagaag ttcgacgata tgttagcaaa aagcaaccat aaacaccagc
    47101 tctttgttgg agaaaagatg aaccatgttt atcctattta cccgattgaa gaggccaaga
    47161 cagcacaata ccaaatcatt gataccataa ataaaaatta gcaatacaaa aatgcctacc
    47221 agacttgagc tttttgccaa agcctggtag gcattttctg atcacagcat gattactgtt
    47281 tcttttctaa ctcacgaagc aattgatcaa ttttattgcc ataggcgata gaattgtcct
    47341 tctcaaaaac caaatccggg attttataca tggttaattg cttaccaagc tcacgcttaa
    47401 tggttcctgt tgcctttttt agacctattt cagccttttg attgtctgaa gctaggtcac
    47461 tcataatggt atagtaaacc ttagcaactg acaaatctcc cagcatttgc acttctgtga
    47521 tcgtaacacc ctgcacacgt ggatcacgaa cctttttgtg taaaatctcg ttgacctcac
    47581 gcttgatttc cataccaaca cgatcaatac gatgatttgt catggccctt cctttctatt
    47641 gtcaaatagt acagactctt aatagctcaa taacaagaga aaagcttgat gactttcaag
    47701 cctttttctc tattaggctg atggctatac tattaatagt gattgttcaa atcaggtggt
    47761 gacattgtct attgtcttag gacaaggcta tttaagctac tagtcaccac gactatttac
    47821 ggataatttc ttccatgacg taggcttcaa tggtatcatc gaccttaatg tcattaaagc
    47881 cttcaatcat caaaccaccc tcttgggcat taccaatctc cttaacatcg tccttataat
    47941 gcttaagact ggctagctta ccatcaaaga taaccacact atcacgaatg acacgtacgc
    48001 ttgaatcacg cgttacctta ccattaacaa ccataaagcc tccgattgtc ccaaccttag
    48061 agaccttaaa ggtttcacga ataatagcct caccaagaac tttttcttga tactcagggt
    48121 caagcttacc tttcatggct tcctcaacct cttcgatcac cttataaata atgctatgca
    48181 agcgaatctc aacatcgtct gtatcagcct gctgacgcgc ctgtggtgtt ggacgcacat
    48241 tgaagcctat gataacagcg tttgaagcct ctgccaaggt cacatctgac tcattgatcg
    48301 caccgacagc agagtgaaca acatttactc gaacgccctc aacatcaatt ttaaggagtg
    48361 aggctgccaa agcttccaca gagccctgca cgtctgcctt gatgatcacg ttaacggttt
    48421 tgatttcccc tgccttgagg gtatcaaata ggttatcaag gctgacacgc tgcgtgtttt
    48481 gacgttgctt gagaagggca cgcttagcac gctcctcccc tgctgcacgc gctgcttttt
    48541 catcagcata gaccgcaaaa tgatcacccg ccataggggt ttcattgaga ccagtaatag
    48601 ataccggtgt ggacggctca gctgatttca cacgacgacc aaggtcattt gtcatggcac
    48661 gcacacgacc aaaggtgttt ccaacaacga ttgggtcttg tacgtgtagg gttccttgtt
    48721 ggaccagaag tgtcgcaacc gcacccttac ctttgtcaag tctagcctca ataaccgtac
    48781 caatcgcacg aaccgtaggg tcagccttta gctcctcaac ctcagctacc aaaagcactg
    48841 tttctagcag ctcatcaatg tttttattga atttggcaga gatttcaaca aactcacact
    48901 caccacccca agcagttgag atgataccat gctcagccaa ttctgaaata acacgctcag
    48961 gattagcccc tggcttgtca atcttgttga tggcaacgat aattggaaca ccagccgcct
    49021 tagaatggtt aatagcttca atggtttgtg gcattacccc gtcatcagca gctacaatca
    49081 aaatggtaat atctgtcact gacgctccac gtgcacgcat gcttgtgaag gcagcatgtc
    49141 ctggtgtatc taggaaggta atcttcttgc ctgcctcctc aatctggtaa gctccaatat
    49201 gctgggtgat ccctcctgct tctcctgttg caacacgaga atttctaagg gtatcaagca
    49261 gggtcgtctt accatgatcg acgtgtccca taatggtaac aaccggtgca cgctcaacaa
    49321 tattctcagg attaaggtag ctatcatcag taaagaagcg ctcaatatca gcttcatcaa
    49381 cctccacctt ggccttagct tcaatgccat aatccaccat taagagctca atggtatcac
    49441 catctaagga ttggttttgc gttgccatca cacccatcat aaataatttc ttgacaatct
    49501 cagctggctc acgcttgatc cgttttgcaa tttcagcaac ggtcattccc tctgaatatt
    49561 caaattcttt tggtagttca tggaatttac gctctgttac tggttttgga gctgtgttgc
    49621 tattcttatg atgcttacct tttttgtttt tcttgttgtt attccagtta ctattctttt
    49681 gatttctcac ttggttttga ctattccaac tcttcttatt tttcttttgt ccatcttcta
    49741 ggccatgatc cctatcatgc gctttgtctg gacgattttg tttttttcga cgcttatcaa
    49801 ccggttttgc taccggtgca gcagctatac tagctaccgg ctcagctggc tcagtagcct
    49861 tagctggggc ttcacgatgc tttttgtcct ctgtctgagc cttgagggcg gctgccttag
    49921 cctcttgcct tgcctgctgc tctaagcgct tcgcctcttc ttgttcacga aaacgtgatt
    49981 ccctttgtct ggcatactct gcgttttgtt cagcctttaa ggcagcagca cgcgccttaa
    50041 aatcaatctt aggagcaccg gcttgggtct gcccttgacg tcctgtatcc tgttgacgac
    50101 tattagcgtt aaaggaacgg tttttgtcac gattaccagc ttgtctatgc ccatcgtttc
    50161 ggttatttcc agatgatggc ctgttatcaa agcgtctatc tctttgctga ttttgtgact
    50221 tgtggccagc tcgctccgtc tgctgacctt gtgatcgtcc aagttgacga tagtctgact
    50281 tgcggtcatt agagcgattt tgcccagcct gccgtctcgc tgcctgctcc ttggcacgtg
    50341 cttcacgctc tgccttgaaa ttgcggctct ttggcttaac agcaaccggc tgtggggctt
    50401 cttgtgtcgc agctggcttt tctgctgctt gaggagctgc tggctgtggt gtagtggcct
    50461 tagctgcttt tgctttttgt tctgctactt gcttgtcttt tgctgaacct gcttgaacgt
    50521 cttttgtcac acctgctgaa aagctagagg caattttgtt agcatctgct tcttcaacgc
    50581 ttgacgcatg gcttttgaca tctaatccta aggatttggc acgctcaacg acttctttac
    50641 tacttttgcc aatttccttg gcaatttcat gtaatctttt ctttgacaat ttgtgtcctc
    50701 ctattcgtct atttcataag agtcctcatt ttctttgaaa atccagcgtc tgcaatggca
    50761 accaccttac gaggcttgcc aattgcagca cttaattcca gtgcactaaa cactgtggag
    50821 acttctacat tgtaataatt acttttatct gttacttttt tagtgatatt tgggccggca
    50881 tcattggcta aaaaaacaag attgacttcc tgatgtcgaa tggctttgat gaccagctcc
    50941 tcacctgaaa tcactttttt ggcccgctga gccagtccaa tcaaatgaga taatctattt
    51001 aaactattca aggcctagct ctcttctttt aactttgtga tcaacatatg caatcacttc
    51061 atcgtaaaag ctctctggca cctccattga gaagctacga ttaaacacct gttttttctt
    51121 tgccataagt gcttcttggt tatctagctt gatataagca ccacgcccat tttgcttgcc
    51181 ggttggatca ataaaaatct gtccctcctt atttttgaca atacgaagga ggtcacgctt
    51241 atcaatgatt tcaccagaaa caagcgactt acgtaaaggt atttttttta ctttaggcat
    51301 aaaacacctc ttttcttaca cttcctcgtc ggttaagagc tcctctgtag ctactgcttc
    51361 agtcattgct gcttcctttt ctgcttcaag gcgttcatat tcgctggctg acttgatgtc
    51421 aatgcgatag cctgtcaaat gagctgccaa acgaacgttt tgaccacgac gaccaatagc
    51481 aagcgatagc ttattatcag gcaccaccac agtcgcacgc ttaagatcgt catcatcaaa
    51541 gagaaccata tcaacctcag caggtgcaat ggcattgtag ataaattcag cagggtcatc
    51601 tacccattgg ataacgtcaa tgttttcttc tactgggatc tcaagtcctg tcttagcatc
    51661 atagcgcttt ggatggaatt tactgataac ctttttgatg ttgctgccgc cacgaccaac
    51721 aatcgtccca atcgcatcaa cattgggatt gtggctacgc acagcaacct tagtacggtc
    51781 acccgcctca cgagaaacac tcataatctc gacggtccca tcaaaaacct ctggaatttc
    51841 ctgttccata atgcgcttga tgaactcagg gtgactacga ctaacaaaga cgttaacccc
    51901 ctttggattg ttttccacct tgtagacata gacatcaatc cgatcatgtg atttgaaggt
    51961 ttctcctggg atttgatcct gatgtgagag ctgagcctct aaggaaccaa ggttaacata
    52021 aatgaaacgt tggtcaaaac gctcaaccgt acccgtcatg atttcacctt catgctgctt
    52081 gtactcattg aaggtgattt ctcgcatctg acgacgcatc ctttccataa tggtttgctt
    52141 tgcagactga gcagccacac gtccaaactc gctgactgac tcttcaaaac gaattttatc
    52201 tcctaactca taggctgagc taatggcaag agcatcattc aggctaattt ccagacggct
    52261 atcaaatacc tcttcaacaa cctcacgaac cgtaaaaacc tgaaaatctg ctgttttatc
    52321 attaaattca atgacgcagg attctgcttg accataacga cgtttataag ctgatttcag
    52381 tgattcagtg actgcctcaa tgatatctgc cttatcaatg tgtttttctt cttccaaaat
    52441 acggaaggct tctagcattt ctttgctcat aatgttgtct accttgctct caaagcttgg
    52501 taaaaatcct ttcttatctt ataaattaat ccatttaggg cttagccaac cgactaagac
    52561 agatcgctca gcaattgcct tataatttga cagctaagcg agccttagcc actgcttggt
    52621 aaggaatctc aactgttttg tgacgcgtct tatctagata atcaatggtt agggtatcgc
    52681 catcaaaagc cactaaatct ccttgaaaaa ccttcacctt atcaattgcc cgataaagac
    52741 tgacattaat atatgagcct accgcagcct tcaagctctc agcagtcttt aaaggacgct
    52801 ctagcccagg gctggaaacc tccagcatat actgatctgg aaaagggtct ggagaaatcg
    52861 tatctaagag tggactgatg agctctgtga gctcagcagt atcctcaaca gtaatcccag
    52921 aagccttatc aactaagata ctaaggacat aatcactgcc cattttgtcg tattcgatgt
    52981 cgaccaattc atagggtgct ttaattacag gttctacggt ttgggtaaca atatcaataa
    53041 tagctgtgtt tgcgatgtta ataacctcct ttactgatga ctgctatacc tctatagcct
    53101 tgtcctcttg ataatcaaca caaaagtggc gagatatttc tcaccaccct tctgtattat
    53161 tttaacctat tataccacaa tcaaaatgaa ttgcaagaaa atccctacta aaagtgtcaa
    53221 taaggcctca aaaatcctat tttttaaaag gagaggagat ctttaacctt gcttttttct
    53281 ctttccttat cccctctaac ctctgtattc atatgataaa ataaaatatt aaagggtaaa
    53341 aaagacaact aaaatattat ttgcggctgc ttcatggtca ttaccaaaac ggaaaaacct
    53401 cccatcagaa cagatctatg catatgcgag agaggccatt ggtaactcaa taacatcatt
    53461 tagtaaagct taaatt
//
LOCUS       DARYSY010000007        53342 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYSY010000007 DARYSY010000000
VERSION     DARYSY010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53342
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            13..1362
                     /gene="gdhA"
                     /locus_tag="TVR04_000330"
     CDS             13..1362
                     /gene="gdhA"
                     /locus_tag="TVR04_000330"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1269046.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGKVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDTDVPAGDIGVGSREIGYLFGQYKRLNAFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     GLIEHGVTAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            1494..1904
                     /locus_tag="TVR04_000331"
     CDS             1494..1904
                     /locus_tag="TVR04_000331"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1269047.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIVSMGFVDLVMFNPVLTAKREAFEAEESCLSLTGQRRTTRYQEIKV
                     DYLDTHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(2096..4102)
                     /locus_tag="TVR04_000332"
     CDS             complement(2096..4102)
                     /locus_tag="TVR04_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1269048.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTATQLAAYLDDAEADFKQTSPDGTSIRVQAGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTTNEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANATLPATGTSQHSAAAMTILGLLTLTGASLFKKKEGQ"
     gene            4550..6271
                     /locus_tag="TVR04_000333"
     CDS             4550..6271
                     /locus_tag="TVR04_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269049.1"
                     /translation="MLTLIVQHIRQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSAALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVKEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQHELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            6273..8024
                     /locus_tag="TVR04_000334"
     CDS             6273..8024
                     /locus_tag="TVR04_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269050.1"
                     /translation="MTLFIKLIKEIKAVTLAFSLAIGFLLVATAGGQMAPLLLQQTID
                     HYLTPIARGKEVPIEGFQRLLLLYLLLIVITAVLRYISYRMLVYSSNRIVANLRNRAF
                     NVMQRLPIAYFDHQPAGKIATRIVNDTETLKNQFYDNLLSQIIVSASQIVFIYVVMIY
                     LDVKSGLLLLLIMPLFYGMQWLYKSLTDQPMKDFYQARSAVNTQVNETMNGVSIIQLY
                     HQEDTILEEFEEQIHQMKTADDRIIFAESVASWTLTELVKYGMIAAILAVIGYQFLQG
                     RSGITVGKLFIYVNYLMRLFDLLSMLVRQLPNIQRSTATGTRLMKLLEAQTEPDKARA
                     IELTDGTVDFTKVYFAYENGKTVLSDITIHADKGETVALVGHTGSGKSSIMNLLYRFY
                     DVQSGLITVDGQNIQEYSRESLRSQMGIVLQDPYLFTGTIASNITMGNPAYSDQDILD
                     ALEKVGVSSMIARLEKGIHEPVYEKGSSYSSGERQLIAFARTLIADPKILILDEATSH
                     IDTETEDIIQQAMEVLKKGRTTFIIAHRLSTIQSANQILVLDKGRIVERGTHQELLDQ
                     QGIYAEMSKLQEEVAVQ"
     gene            8560..9438
                     /gene="mvk"
                     /locus_tag="TVR04_000335"
     CDS             8560..9438
                     /gene="mvk"
                     /locus_tag="TVR04_000335"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1269051.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIISQVPQKRGMGSSAAVSIAAVRA
                     VFSYFQQPLSGELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCLTEAVEQAIKTKDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVEAALEAGALGAKMTGGGLGGCMIALAERVTDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            9420..10364
                     /gene="mvaD"
                     /locus_tag="TVR04_000336"
     CDS             9420..10364
                     /gene="mvaD"
                     /locus_tag="TVR04_000336"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1269052.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEVKMIPSTSSISLTLEGMYT
                     TTSLSFLLPSAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQAFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGRLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQKGYPCYFTMD
                     AGPNVKVLCLEEDLERLSRLFEREYRIIASKTKELPDV"
     gene            10357..11355
                     /locus_tag="TVR04_000337"
     CDS             10357..11355
                     /locus_tag="TVR04_000337"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1269053.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYVDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVLLTLRALAAYYQVHLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRCKVSQWLTEMTLKELMAAHWGYTIETIEPALPCWFLVGWTKVPSISREM
                     IQLVNKNISYPFLEQSQKVTQEVMTALQLGQSERLKAGIEKASQLLQGLASVIYHPKL
                     MQLVQACQGLDAAAKSSGSGGGDCGIALVFDTKDIEPILARWQQAGIVLLYQEEWG"
     gene            11358..12350
                     /locus_tag="TVR04_000338"
     CDS             11358..12350
                     /locus_tag="TVR04_000338"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1269054.1"
                     /translation="MTNRKDDHITYALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVA
                     LELVETYPVEQVIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(12625..13908)
                     /locus_tag="TVR04_000339"
     CDS             complement(12625..13908)
                     /locus_tag="TVR04_000339"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1269055.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDIANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSARCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARNGAYRGLSSWHVDTSKNSLCGELTLPMPIASKGGSIGLNPT
                     VNVARSLLEQPNAKVLAQIITAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAKQLLIAIRLNQS"
     gene            complement(13895..15073)
                     /locus_tag="TVR04_000340"
     CDS             complement(13895..15073)
                     /locus_tag="TVR04_000340"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1269056.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAICFHIPFPKLALKGLHKIMTKSLLADNHKEKLYENFQASIAYSKQIG
                     NIYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQ
                     ALLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN
                     "
     gene            15258..16097
                     /locus_tag="TVR04_000341"
     CDS             15258..16097
                     /locus_tag="TVR04_000341"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1269057.1"
                     /translation="MTKADQIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWRAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACHPKLLLHVPDGTDFFDIRPEDFELQDYHPVKPQLTFD
                     LAI"
     gene            16178..16675
                     /locus_tag="TVR04_000342"
     CDS             16178..16675
                     /locus_tag="TVR04_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1269058.1"
                     /translation="MTKKIIAIWAEDEAGLIGTCGKLPWYLPKELQHFKETTLHQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTKNSHYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGHFDAIIKTVVHHRFEGDTYSPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            16695..16865
                     /locus_tag="TVR04_000343"
     CDS             16695..16865
                     /locus_tag="TVR04_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269059.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            16901..18130
                     /gene="clpX"
                     /locus_tag="TVR04_000344"
     CDS             16901..18130
                     /gene="clpX"
                     /locus_tag="TVR04_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1269060.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVR
                     ITKEAVEGQSKPVLEIA"
     gene            18140..18739
                     /locus_tag="TVR04_000345"
     CDS             18140..18739
                     /locus_tag="TVR04_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1269061.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHEPSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            19103..22114
                     /locus_tag="TVR04_000346"
     CDS             19103..22114
                     /locus_tag="TVR04_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1269062.1"
                     /translation="MTIKKCPQILALSLALAALASQAQAVHALEQQEISVKQAQESSD
                     WFNEDEDFRAVKSNTSTEIDSTVTDLFGDAESKTKAGKEELKAPSSKQEALPAEPQKE
                     KETSAKPTDHATAQVEEAQPEQDSDNPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLT
                     LPRIGADKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRNILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLADSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERAFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHVVLRTKSGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNKWLAEDFTYTGQMITGFSASGLRKVKRNKHLVLPKDYQGQPLTAIADNA
                     FRNVDFHDKALRKYDLERVTLPSTIQKIGAFAFQSNNLESFEASEDLVDIGQGAFMNN
                     RIEILTLNDKLRVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVVFMGDKLTS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDNLIRIQAEAFKANRLQ
                     GVTVPDTVISISFNAFDNNSDDKVILRTINHNKNLLADGDGFIVDPDLLSADQSSVQA
                     VLEDLQRLDLASLRADTAAHFTTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKSADIALSNHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKISRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKKLLPKTGA
                     FKEAWVTMIGMLVLLAAALLKGDSRYKKRSK"
     gene            complement(22298..24391)
                     /locus_tag="TVR04_000347"
     CDS             complement(22298..24391)
                     /locus_tag="TVR04_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1269063.1"
                     /translation="MATYYGKDPFGNMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAVAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEIAK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGANDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDSADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLAEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            24762..25181
                     /gene="ndk"
                     /locus_tag="TVR04_000348"
     CDS             24762..25181
                     /gene="ndk"
                     /locus_tag="TVR04_000348"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1269064.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDALINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            25682..26488
                     /locus_tag="TVR04_000349"
     CDS             25682..26488
                     /locus_tag="TVR04_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1269065.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVADTPVLNRSEKAVY
                     ANDFGSGNRASDYVPAAKAWSFEAYPDYYRVLGASHLNPAIFPEAGNMSYSPLDELGR
                     TQVARGTINYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     MPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTINYATGAFQSN"
     gene            complement(26785..27750)
                     /locus_tag="TVR04_000350"
     CDS             complement(26785..27750)
                     /locus_tag="TVR04_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1269066.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKANNKKASHTDSQQQKGAVSWTKQQAPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKHGIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            27921..29204
                     /locus_tag="TVR04_000351"
     CDS             27921..29204
                     /locus_tag="TVR04_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1269067.1"
                     /translation="MSVKIALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DEITKKHLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGDLLTLAAKHQVALYYEAAVAGGIPILRALADSFTSDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYEMALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGVT
                     IDFEAISYSGIDKIRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIVSPYYFAIQATNKFGQLLELTRLCDACGIKIEELLSNETGSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            29206..30066
                     /locus_tag="TVR04_000352"
     CDS             29206..30066
                     /locus_tag="TVR04_000352"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1269068.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTADRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNERKMAIYDAIDQLGLTGQLVSL
                     ELDRQGLCLV"
     gene            30231..31490
                     /locus_tag="TVR04_000353"
     CDS             30231..31490
                     /locus_tag="TVR04_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1269069.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIKGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANRI
                     RPLTDRLVSETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFNYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            31490..32113
                     /gene="folE"
                     /locus_tag="TVR04_000354"
     CDS             31490..32113
                     /gene="folE"
                     /locus_tag="TVR04_000354"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1269070.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSRRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            32121..32921
                     /gene="folP"
                     /locus_tag="TVR04_000355"
     CDS             32121..32921
                     /gene="folP"
                     /locus_tag="TVR04_000355"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1269071.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLATEYDVPIILMHNQTEEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLSEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            32928..33287
                     /gene="folB"
                     /locus_tag="TVR04_000356"
     CDS             32928..33287
                     /gene="folB"
                     /locus_tag="TVR04_000356"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1269072.1"
                     /translation="MDKIRLEACRFYGYHGAFEEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFDQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            33284..33790
                     /gene="folK"
                     /locus_tag="TVR04_000357"
     CDS             33284..33790
                     /gene="folK"
                     /locus_tag="TVR04_000357"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1269073.1"
                     /translation="MTLVYLGLGTNMGDRAGYLKAAVAALSKLPDTELLRQSSIYETA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DELYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            33886..34773
                     /gene="murB"
                     /locus_tag="TVR04_000358"
     CDS             33886..34773
                     /gene="murB"
                     /locus_tag="TVR04_000358"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1269074.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIKTV
                     EQTSGVRLEPEVRIIGESL"
     gene            34819..35973
                     /locus_tag="TVR04_000359"
     CDS             34819..35973
                     /locus_tag="TVR04_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269075.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGKRINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHEDGLINAIEEERNEENL"
     gene            35957..36751
                     /locus_tag="TVR04_000360"
     CDS             35957..36751
                     /locus_tag="TVR04_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269076.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            36748..37524
                     /locus_tag="TVR04_000361"
     CDS             36748..37524
                     /locus_tag="TVR04_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269077.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            37517..38590
                     /locus_tag="TVR04_000362"
     CDS             37517..38590
                     /locus_tag="TVR04_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1269078.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYRNSIMLVDGAREILGVGLTTFGCSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDVKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            38748..40280
                     /locus_tag="TVR04_000363"
     CDS             38748..40280
                     /locus_tag="TVR04_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1269079.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMIS
                     EKVIDYYHQAHSNLMLLVPIAGFSILAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWRSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALNQYWLLLILGLVLGCLGFLYEKVILHFHRVYDFLGKSLHLAPHFYGLI
                     VVAIILPIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLTFQQIGLLDHQLIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLRLPKNVLITTQIHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            40485..41099
                     /locus_tag="TVR04_000364"
     CDS             40485..41099
                     /locus_tag="TVR04_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1269080.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRVIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            41408..42535
                     /locus_tag="TVR04_000365"
     CDS             41408..42535
                     /locus_tag="TVR04_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1269081.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKAKRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKTVH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQPS"
     gene            42703..43380
                     /gene="radC"
                     /locus_tag="TVR04_000366"
     CDS             42703..43380
                     /gene="radC"
                     /locus_tag="TVR04_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1269082.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQELLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(43382..44077)
                     /locus_tag="TVR04_000367"
     CDS             complement(43382..44077)
                     /locus_tag="TVR04_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1269083.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTGFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDTFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQGIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGIIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(44089..44733)
                     /locus_tag="TVR04_000368"
     CDS             complement(44089..44733)
                     /locus_tag="TVR04_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1269084.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(45019..45366)
                     /locus_tag="TVR04_000369"
     CDS             complement(45019..45366)
                     /locus_tag="TVR04_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1269085.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(45356..46483)
                     /locus_tag="TVR04_000370"
     CDS             complement(45356..46483)
                     /locus_tag="TVR04_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1269086.1"
                     /translation="MIYFDNAATTPLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGTAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEVKNGIIDLDQLKAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLD
                     PLLHGGNQENKRRAGTENLINIIGMTQALDEAIARLPQHYQHAKELSQLLLDELADIS
                     YQLNHSDHHLPYIVNIGFPSYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRISFSEQNTQKDVIALATQLKHILGGSYGI"
     gene            complement(46486..47460)
                     /locus_tag="TVR04_000371"
     CDS             complement(46486..47460)
                     /locus_tag="TVR04_000371"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1269087.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILERAGATDIYAVASHGLFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(47602..48174)
                     /locus_tag="TVR04_000372"
     CDS             complement(47602..48174)
                     /locus_tag="TVR04_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1269088.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDIDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVKGKV
                     DFDHFLARHQITFKYAKSKVARFSKTLRKS"
     gene            48269..48940
                     /locus_tag="TVR04_000373"
     CDS             48269..48940
                     /locus_tag="TVR04_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1269089.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVIEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            48915..49751
                     /locus_tag="TVR04_000374"
     CDS             48915..49751
                     /locus_tag="TVR04_000374"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1269090.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPGFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDI
                     ES"
     gene            49748..50644
                     /locus_tag="TVR04_000375"
     CDS             49748..50644
                     /locus_tag="TVR04_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1269091.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEEPFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIEQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDIRLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKR"
     gene            50655..51656
                     /gene="pta"
                     /locus_tag="TVR04_000376"
     CDS             50655..51656
                     /gene="pta"
                     /locus_tag="TVR04_000376"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1269092.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFADQHYTIINPNDYADFEKMKAAFVELRKGKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENEPIN"
     gene            51756..52514
                     /locus_tag="TVR04_000377"
     CDS             51756..52514
                     /locus_tag="TVR04_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1269093.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSKPAAIDRALAALPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMVNTNIIGLIYLTRQVLPQMVSTNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLVGTKIRVTNIEPGLCEGTEFSHVRFNGDQARVEALYAGAHAIQPRDIANT
                     VSWIINQPEHVNINRVEMMPVSQSYGPQPVSRHD"
     gene            complement(52618..53304)
                     /locus_tag="TVR04_000378"
     CDS             complement(52618..53304)
                     /locus_tag="TVR04_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1269094.1"
                     /translation="MTKMIYTLALVDDKNSLQNTFFTTLSQRFSYLFHITIVRQLTAE
                     QLKKAQAIFTFQDLEASLPVLYFNQADKEQGFTVSDHTFTDGQQALGLAKYLTQFYQA
                     LTPHFLTYLPFQARIADHQGQIVFDNQRFNGSFFASDEHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDSKQFVGVYDTILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
BASE COUNT        14918 a        10213 c        12325 g        15886 t
ORIGIN      
        1 agaggatata taatggtatc agcaaaagac tatgtagcta gtgtttttga taaggtcaaa
       61 agggataatc cgcatgagac tgaatttctt caggcggtca aggaggtatt tgattccttg
      121 attcctgttt ttgaaaaata ccctaattat attgaggaaa atctattaga gcgcttggtt
      181 gagcctgagc gtgtgatttc ttttagggtt ccttgggttg atgatcaggg caaggttcaa
      241 gttaatcgtg gctaccgcgt gcaattttca tcagctattg gcccatataa gggagggctt
      301 cgctttcacc cttctgtcaa ccagtctata gttaaatttc ttggctttga gcagattttc
      361 aaaaatgctc tgactggtca gcctattgga ggaggaaaag gaggatcaaa ttttgatcct
      421 aaaggcaaat cagacctaga aatcatgcgc ttcacacaaa gctttatgac agagctacaa
      481 aggcatatcg gccctgatac tgatgtccct gccggtgata ttggtgtggg aagtcgtgaa
      541 attggttatt tgtttgggca atataagcgc cttaatgcct ttaagaatgg tgtgttgaca
      601 ggaaaaggtc tagcctacgg tggctcccta gctcgcacag aggccacagg ctatggcgtg
      661 gtttattttg ctcagcaaat gctggcggct aaggggcagg acttggctgg taaaacagct
      721 attgtatctg gatcaggaaa tgttgccatt tacgcaacgg aaaaattgca ggccttaggt
      781 gttaaggtat tagcagtgtc ggattcctct ggttacgttt atgatgataa gggcattgat
      841 cttgagaccc taaagcaaat caaggaagtg aagcgtgagc gtatcaagac ctatctagag
      901 agtcacccgg ctgctgtgtt tacaccggct ggtgagggat ccatctggac tattaaggca
      961 gaccttgcct ttccatgtgc gactcaaaat gagctacaag aggcagatgc taaaggcttg
     1021 attgagcatg gggttacagc tgttgtcgaa ggggctaaca tgccctcaac cttagaggct
     1081 attgagcaat ttcagcaggc tggggttctt tttggccctg ctaaagcagc aaatgctggc
     1141 ggtgtagcag tttctgcgct ggaaatggca caaaatagcg gacgtaccgc atggaccttt
     1201 gaagaggtgg atcatcgatt gtatgacatc atgaaggcta tttatcaaaa agcagccgca
     1261 gccgccaagg aatgtggtca agaaggcaac ctagtggtgg gagctaatat tgcaggcttt
     1321 ctcaaagttg ctcaggccat gtcagcacag ggaatcgttt aagagctgtg gctggtatat
     1381 gctgcatata tcagtagggt tagcacatta gtcttagctt aatgacgtta ggatacacga
     1441 tcggtcatct agacaatgca tgccgattag agcaataaat caaggagaag atgatgatca
     1501 aaaaaatcgt gaaggacacc tttttcttgc agcaaaaggc acagccagca acgaaaaagg
     1561 acctttggat tggtcaagac ctgcaggata ccttagctta ttatcgtgat agctgcctgg
     1621 ggctggctgc taatatgata ggggaaaaca agagggttat tattgttagc atgggctttg
     1681 tggatttggt gatgtttaat cccgtattaa ctgctaagcg tgaagccttt gaagcagagg
     1741 aatcctgcct atcactaaca ggccaacgta ggacaacgcg ttatcaggag atcaaggttg
     1801 attatcttga tacacattgg cacaagaaat ccctacgatt gacaggctta ccggcacaga
     1861 tctgccagca tgagctggat catctggagg gcatattaat ttaaatcatg accacccgtt
     1921 actgaagtgc ccccattcgt tagagtttct atctaacttt tggaagggca gtctatagat
     1981 gggtggttta tttgtctcgc tccacaggtg cgaggcgaac taaaagtcgt ataatcaaaa
     2041 aaccggctgt atgcttaaga tacagtcggt tattgctgtt atagctaagc cggttttatt
     2101 ggccttcctt tttcttgaaa aggctagcac cagttaaggt tagtagtcct aggattgtca
     2161 tggcagcagc agaatgctgg cttgttcctg ttgctggtaa ggtagcatta gcttgctttt
     2221 tagctgctag aggcttgatg cttgtggcag gattagcatt ttgagcaggc gtaaatagat
     2281 cagagacgag ctcagtagca agcaccttgc cctcacgatt cttaaagacg cggttgatga
     2341 tctcgtgctt gccggtatgg tcactttgag tagagccttc aagactggca gtgacatagg
     2401 ttttcacacc gttaatacca gcacttacag tctttccagc tgcttcaagg tccttgatgt
     2461 attcgataaa gacctcagta tcaggattaa tggctcctag tagcttagcg tccttaaaga
     2521 cggagaagcc atcaccaccg ccatatagga agtcgttgat gattagggtg tattgagctg
     2581 ctggatcaat ttcttcacca ttatctttat aagcctttac taccttaaac ggtgttgaag
     2641 gatcgttagc ctcattagtt gtataagtgt atttgagtcc agacatttga aggaagtatt
     2701 tttggtcttc atcgtattgt tggttcaaga catcataaat ttgttggcca gtcatttgaa
     2761 cgacctgaag aatattgcca aaaggttgaa cagcctgtgc agctccccag gtaatggttt
     2821 gatcctcttt gaccaccaag tcagcgcgaa taccgccatt atttgtcatg gcaaaatcaa
     2881 catgagggaa ggtttttcta ccaatggtta attgggcagt tgttatcaaa ttgccaacag
     2941 gagattcctt gtcttcgttt tctgttttag aaatcgttga agaggtagct gctgtaccga
     3001 tctttagctc ggtaacggtt ttgacaatgt cattggcttg atcaacaatg gcttgaatgt
     3061 cggcattgcc tgtttttatg ccaggagcaa cggcaatgac ctttgcttca ggagtggcta
     3121 caaaatcatt gaggtcagtg tctagtgttc cacgaacatc tgcataggct ttcccctgtg
     3181 aaacagcctg aacgacacgt gttgtgccaa tggtaccgtt ggtgtattgg tggttgtgac
     3241 cagcaaagac aatatccaca ctatgctcag gataaagctg gttaaccttt tccataactg
     3301 ctgccatctc atcatgaact accccgttat cacttgttgc tgggatatga gctaggacaa
     3361 caatcgcatt gacctgctgc tcttggagct ctttagcata tttaacgatg gtttctgcag
     3421 agtctaggta atcatattgt tcataatttt gttttaggac aaggtttgga atttctgttg
     3481 ttacaacacc gataaagccc accttgactg acttatcatt aactgggact tctttgacag
     3541 cataaggctt ccagccaaaa ggaatcgtgt tggtctcctt gtcaacgaca tttgcaatga
     3601 caagggtttg atttgaagct tcatgctcgt attgcttagt aatgtcgttg atagctgagt
     3661 cttcagcagg tgcagtgcct gtcatgatac ggttgaattc agctaagccc tcatcgaatt
     3721 cgtgattccc aagggttccg tattcaaagc ccatctggtt gaatacctta accgttggct
     3781 cgtcctgtaa tagtccagaa ttagcaggac tagctccgac catatctcct gcttgaacac
     3841 gaatgcttgt cccatctggg cttgtttgct taaagtcagc ctctgcatcg tccagatagg
     3901 cagctaattg tgtggcagta cctgcgttag atacctttcc ttctggcatg taggcagagc
     3961 cggttgtgtc taaggcacca tgaaagtcat tgactccaag aaattgcacg tctacctgat
     4021 cggcctgcac gccggttact agcatagaaa ctccggcaaa gacaccaaga acactacttt
     4081 ttaaaacaaa atgctttttc ataaacgctc ctaaaagttt aaagtattgt cacaagttaa
     4141 gtgtactatt atttaaatga gaattcaaca aaaattaata aaaaagctaa caaaaattca
     4201 acgatagcgt ttgctaatca ctgaaaacgt ttaaaatgca aacattggaa gcgttttttg
     4261 caaaaaatag aagaactatc caaaaaaggc tttacaagcc cagtattcta tgataagatg
     4321 ttaggcagat taaaagaaag gagaaattaa taatgaaccg tttcattcaa ctatttaacc
     4381 attattacga tagtctcctt tctaaccaaa acagttagtt tcttttagtt tcactaaata
     4441 gaaataataa agcccgcggt aggaaggata tcttattgcg ggctttttgt gtgcaaaaat
     4501 cctattttaa gacagcttga aataggttag ttcagaaatg gaggatatga tgctgacctt
     4561 aattgttcaa catattaggc aaaagaaatg gatttatatc cttattgcaa tgactttagt
     4621 gatatatgat gcctcacttg tgataccaac aagggttatt caagacttgg ttgatttgat
     4681 gtcaaggcat cagctaagct cagcggcatt ggtgaggcat gttatcattc ttttggctac
     4741 ggcagtggtg tcttatggag ttgcttattt gtggcatctt catttgtttc aggaggcagt
     4801 tcattttaag tttgatattc agcagcgtgc ctttcgaaag cttgttttta tgagaacgcc
     4861 tttttatgag aaatttcgct caggtgacat gatcacgcgt ttttcaacag atgtcgaagc
     4921 acttatggac cttatcggct atggcttgat gattatccta tatgctggtg gtatgattgc
     4981 ttttattatt ccgaccatgt ttttgatttc ttggaaaatg accttgatag gaatagtacc
     5041 gattttgctt atgatggtga tgatctatgg tgttacgaaa aagcaagagc atttggttaa
     5101 agaggcgcgt gaggcgattt caagccttag tgatgaggta ctagaaaccg ttgagggcat
     5161 tagagtgatg cgtgcttaca gtaaaaaaga ttatttggca cttcattttg ctcaaaagac
     5221 tcagaatttg gcagataaat ggaatcaggt ggccaagtat cgtgccttgt actttcctct
     5281 ttacagcgtc atgattgcca ttagtacagt aatcatttta atggtaggcc tacagctcat
     5341 agcaagctca gaggtaacac ttggtcaagt cattgcgctg cagctttatc tggtgtcttt
     5401 ggtggagccc tttggcatgc tgtcagactt tattttggtt tatcagacag gaaaaacctc
     5461 ttttggtaag attaatgagc tcattgaaac aagtgatgat atggagcctg atggccagca
     5521 tgagttagag agctttgatc agattgcttt tatagactat agctttacct atgccaatag
     5581 ttctaggcct agcttagaaa agatcaattt aaccctgaaa aagggacaaa ccttagggat
     5641 tgttggtaaa acaggctctg gtaaaacaac ccttgtcagg cagtttttga gacaataccc
     5701 tcttgggcag gggcagctga tgattaatca tcgtagtgtc ttggattata agcgtcaatc
     5761 acttgagcgt cagattggct atgtgccaca ggagcatatc ctgttttcaa aaacggttgc
     5821 tcaaaacatt gcgatgggga aaaaggcagc tacaactgag gaaatcttgg aggcgattga
     5881 aactgcggcc tttacgcgtg atgttcaagg aatggcaaag ggcttggata ctgagattgg
     5941 agagcgtggt ctgtctattt caggaggtca aaagcagcgt atttcgattg ccagagcctt
     6001 tttgtcccag ccagatttgc tgattttaga tgattccctg tcggcagttg atgctagaac
     6061 agagactgat attattcgac acattcaaga cgaaagaaag ggaaagacaa cacttattgt
     6121 tagccatcgc ttgtctgcga ttcagcatgc cgattgggtt attgttctgg atcaggggca
     6181 gatagtagag gaaggtcagc cccaacaact tttagctcag aagggctggt attatgaaca
     6241 gtaccagcgt cagcaggctc aggaggttta agatgaccct atttataaaa ttaataaaag
     6301 aaattaaagc tgtgaccttg gctttttccc tggcaatagg ctttttgcta gtggcaacag
     6361 ctggaggtca gatggctccc ttattgttgc aacaaacgat tgatcattac ttgactccga
     6421 tagctagagg aaaagaggta ccgattgaag gctttcagcg cttgctcctg ctgtatttgc
     6481 tgttaattgt gataacagca gttttgcgtt atatctctta tcgaatgctg gtttattcct
     6541 ctaataggat tgttgctaat cttcgtaatc gagcctttaa tgtgatgcag agactgccga
     6601 tagcttattt tgatcatcag cctgcaggaa agattgcaac taggattgtt aatgatactg
     6661 agaccctgaa gaatcaattt tatgataacc ttttgtctca aattattgtt agtgcttcac
     6721 agattgtgtt tatttatgtg gtgatgattt accttgatgt gaaatcaggc ttgctcttgc
     6781 tgcttattat gcccttgttt tatggcatgc aatggctgta taaaagcttg actgaccagc
     6841 caatgaagga tttttatcag gccaggagtg ctgtcaatac gcaagtcaat gaaaccatga
     6901 atggtgtttc tattattcag ctttatcatc aagaggatac gatcttagag gaatttgaag
     6961 agcagatcca ccagatgaaa acagctgatg ataggattat ttttgcagag tcagttgctt
     7021 catggacgct gacggaattg gtaaagtatg gcatgattgc cgctattttg gctgttattg
     7081 gttaccagtt cttgcagggg agatcaggca tcacagttgg taagctcttt atttacgtta
     7141 attatttgat gcgcttgttt gatttattaa gtatgctggt taggcagctg cctaatattc
     7201 agcgctcaac agcgacagga acgcgcctga tgaagctgct tgaggcgcag acagagccgg
     7261 ataaagcacg agcaattgag ctaacagatg gcactgtgga ttttaccaag gtatattttg
     7321 cttatgaaaa tggcaagaca gttttatctg atattaccat tcatgctgat aagggggaga
     7381 cggttgccct agtagggcat actgggtctg gtaagtcatc tatcatgaat ttgctgtatc
     7441 gcttttatga tgtacaatca ggcctcatta cagttgatgg gcaaaatatt caggagtatt
     7501 ctagagaaag tctgcgctca cagatgggta tcgtcttaca ggatccttat ttgtttacag
     7561 gaacgattgc ttctaatatc acgatgggaa atccagccta ttcggatcag gatattttag
     7621 atgctttgga aaaggtcgga gtctcttcga tgattgctcg tctggaaaag ggcattcatg
     7681 agcccgtcta tgaaaaaggc tcctcttatt cgagtggcga gagacagcta attgcttttg
     7741 ctaggacatt gattgccgac cctaaaattt tgatcttaga tgaagcgacc tcgcacattg
     7801 atactgagac agaggacatc attcaacagg ctatggaggt cttaaagaaa ggccgaacaa
     7861 cctttatcat tgcccatcgc ttgtctacca ttcaatctgc taatcaaatt ttagtattgg
     7921 ataaggggag gatcgtcgaa agaggaacac atcaggaatt gctagatcag caaggcattt
     7981 atgctgaaat gtccaagcta caagaagagg tggctgtaca gtaatgcttt ttagtgatag
     8041 ttatctaaac agctcctttt ccagattatg ttaagagtgg tagtctgtga agtaggaaca
     8101 acgtttaggc tttgtgtcta agcctctaag gcttttaaga ggctggatca gggctcagcg
     8161 tcaacaaaat cacatgtcac tttatcacag catgctgtga tgaagtgttt tttgtgtcgt
     8221 cctgctgagg agaaggctct cacagtcagc acttgtctga ctccttcatc gaagttaggt
     8281 gattgatacg atatctgagg tacagcactt gctccttgtt agcctaagct tgttttgaga
     8341 tcagcctgtc agcaatctat gctttgtgtc tgacctttag cagcttgtag atgaagtagg
     8401 gctaaaggac actttaattg atgaggaatt accttaaaaa tccatttccc agatgagata
     8461 agaacggtct aaaaggggat agataatcgc aatttttaac aatttagtgt aaaatagtaa
     8521 ggtgaatgtt ttgatgaagt agacgaaaag atttaggata tgaataagac aattggatat
     8581 ggcaaggcac acagcaaaat cattttaatg ggggagcatt ctgtggttta tggttaccct
     8641 gcgctggcct tgcccttaaa agacattgaa gtgacctgcc ggattttccc tgcagcaaaa
     8701 cctttagcct ttgattttta tgatccctta tcaacggcag tttatgcagc cttggagcat
     8761 ttggggtgct tggcagagcc cattcattat gatattattt ctcaggtacc acaaaagcgg
     8821 ggcatgggtt cctcagcagc tgtttcgatt gcagctgttc gagctgtttt ttcttatttt
     8881 cagcagccct tgtcaggtga gctcttggaa atcctggtga ataaggcgga aatcattgcc
     8941 cataccaatc ccagtggcct agatgctaag acctgcctta gtgataaggc catcaaattt
     9001 attagaaatg ttggctttga taccattgat attcagttaa atgcttattt ggtcattgct
     9061 gatacaggga ttcaggggca tacgcgtgag gctgtcaata aggtggctca atttgaggag
     9121 gaaaatcttc ctcatttagc caagcttggc tgcttaacag aggctgttga gcaagcgatt
     9181 aagacaaagg attgcctagc tattggacga ttcatgacac aggcacatga atcactaaag
     9241 gctattggtg tcagtgtggc aaaggccgat cagctggtag aagcagctct tgaggctggc
     9301 gctttaggcg ctaaaatgac tggtggcggc ttaggagggt gtatgatcgc attagctgaa
     9361 agggtaacag acgctcagca aatcagtaag aaactaaaag aagagggagc tgtaaatacg
     9421 tggattcaaa tactgtaacg gtaacttcct acgctaatat tgctattgtc aaatactggg
     9481 ggaaaaaaga tgaggttaag atgatcccat caacctctag tatttctttg accttggaag
     9541 gcatgtacac aacaacaagt ctttcttttt tacttccctc agcaaaggga gatcagttct
     9601 atatcaatgg tgtcttgcag gacgccaagg agcatgctaa gattactgcg attttggatc
     9661 agttccgtca gaaggaccag gcttttgtca aggttgaggc aagcaacagc atgccaactg
     9721 cggcaggttt atcctcaagc tctagtggct tatctgctct ggtaaaggcc tgtaatcagc
     9781 tttttcaagc taagctaagt caagaagagc ttgcccaaaa ggctaagttt gcctctggct
     9841 ctgcgtcgcg ttcttttttt ggccctgttg ctgcctggga taaggataca ggctctattt
     9901 ataaggtcaa aacagattta aagctggcca tgattatgct ggtcttgaac gatgctagaa
     9961 agcccatttc gagtcgagag gggatgaagc gctgcagtac aacctcaaca agctttgacc
    10021 agtggctggc ccagtcagaa agtgattatc aggccatgct gcgtgccctt agtgacaatg
    10081 attttgaaac ggttggtcgg ctgacagaag caaatgctct agccatgcac gcaacgacca
    10141 aaacagccag tccttccttc tcttacctaa cagaggcctc ctatcaggcc atgctaaggg
    10201 ttaaagagct tcgccaaaag ggctatcctt gctattttac aatggacgct ggcccaaatg
    10261 tcaaggtgct ttgtttagaa gaggacttag agcggctgtc gcgccttttt gaaagggagt
    10321 atcgtatcat tgcctcaaaa acaaaggaat taccagatgt ctaaatacca tgttcaagca
    10381 ggaggaaagc tgtatctgac aggcgaatat gcgattctaa ggccggggca aacggcgtta
    10441 atttgctata ttcccataat gctgacagct gtcattgaag cagcagaggc tgttagtatc
    10501 agctcagata tgtttgacca tgctgctgat ttgtcaccgg ataaggatta taggctgatt
    10561 caagcctcta ttgaagcctt tagtttatat gtagataagg atattaagga gctgccagcc
    10621 ttttctttgt ctattactgg taagcttgag cgtgacggta aaaagtttgg gattggctct
    10681 agcggtagtg ttgttctctt aacgctaaga gcgttggcgg cctattatca ggttcatttg
    10741 ctgccagagc agctctttaa gctggctgct tacaccctgc ttaaatcagg agataatggc
    10801 tccatggggg atattgcctg tattgcctat gagagtctgg ttgcttatac ctcctttgat
    10861 aggtgtaagg ttagtcaatg gttgacagag atgaccctaa aagagctaat ggcagcacat
    10921 tgggggtata cgattgagac tattgagcct gctctgccct gttggtttct tgttggctgg
    10981 acaaaggttc cttctatctc aagagagatg attcagctgg ttaacaagaa cattagctat
    11041 ccgtttttag agcaaagcca aaaagtcaca caggaggtga tgactgcctt gcagcttggt
    11101 caaagcgaga ggctcaaggc tggtattgaa aaagcgagtc agttgctgca agggttggct
    11161 tcagttattt atcaccctaa gcttatgcag cttgtccagg cttgtcaagg gcttgatgct
    11221 gctgccaaat catcaggctc agggggtggg gattgtggta ttgcactcgt ttttgatacc
    11281 aaggacattg agcctatcct tgccagatgg cagcaggcag ggatcgtatt actttatcag
    11341 gaggaatggg gatagacatg actaatcgta aggatgacca tatcacatat gctttgagct
    11401 atcattctcc ttacaatgca tttgacgaca tggagctcat tcactgttcc ttgccgagct
    11461 atgatttagc tgatattgat ctctcaaccc attttgctgg ctgtgatttt gagtttcctt
    11521 tttatatcaa tgcgatgaca ggtggtagca agaaaggtca agcagtcaat gaaaagctgg
    11581 ccaaagtggc tgcggctaca ggtattttaa tggtgacagg ctcttacagt gcagccttga
    11641 aaaatcctga ggacacttcc tttcaattgc gaggtgtagc accagattta cagttggcca
    11701 ccaacattgg tcttgataag gctgttgacc tagggattag agctgtcgag gaaatgaagc
    11761 ccttgttttt acaggtacat gtgaatgcca tgcaggagct gttaatgcca gagggagagc
    11821 gcagctttaa gcattggaag gatcatttag cggcctatgc caagcagctt ccagtccctt
    11881 tgattttaaa agaggttggc tttggcatgg atattaagac catcactata gcacgtgata
    11941 tgggagtaaa aacctttgat atttcaggaa gaggaggaac ctcctttgcc tacatcgaaa
    12001 atcaaagagg aagtaatcgc tcttacctag acgattgggg acagacaaca gtgcaatgtc
    12061 tattaaacgc caaaggtctg gttgatgaag tggagatctt agcctcaggt ggtgtcagac
    12121 accccttaga tatggttaaa tgcttggtgc tgggggcacg tgctgtgggc ctatcgcgag
    12181 tggcattgga gttagttgag acctatccag ttgagcaggt catcgctacg atcaacagct
    12241 ggaagaagga gcttaagctc atcatgtgtg ccttggattg tcgaaccttg agcgatttgc
    12301 gtcaggtgga ttatttatta tatggcagac tttatcaggc aaaccgctaa aggcttttta
    12361 gttctgagct agctttcctt agaaaatcat cacaagggtt aatcaactgc ctgcttggta
    12421 attcagctga ttatggctag taaggttctt agatgtctga atgaatgata ggacagatga
    12481 catagtatag cgctaacctt tagtgaaaat cagttcctgg tcaggttact gagactgagg
    12541 ttaagtctat gcttacatta acatctaaag aatatgaaaa cacttggtag ctgccattaa
    12601 agctgttacc aagtgttttt tagtctatga ttgatttagt cgtatggcta ttaagagctg
    12661 ctttgccttt tccagattca ttggcttatc ctttagtaaa gccttgacta gttgaggcac
    12721 ctcctgctca ctagcacctg ctaacagagc tagtgactta gcctgcagct tcatgtgacc
    12781 agcctgaata ccagttgagg tcaaggcctt tagagcagca aaattttgcg ccaacccaac
    12841 tgcggtgatg atttgggcga gtaccttggc atttggttgc tctaaaaggc tgcgagcaac
    12901 attgacagtt gggttgagac caatcgagcc ccctttactg gcaatgggca ttggcagtgt
    12961 taactctcca cataagctat ttttagatgt atcaacgtgc cagctactta gtcctctata
    13021 agcgccattc cttgcggcgt aggcatgtgc tccagcctca atagctctcc agtcatttcc
    13081 agtagctata gctactgcgt cgattccatt gaagattccc ttattatgcg ttgctgctcg
    13141 gtaagggtca atctgcgcta gtttacttgc cagttctatt tttttggcta attgctgggc
    13201 ttcttcctta tgtcgactta agtatctgag gtcaacctga cacctagcac taactaaagc
    13261 ttttgttgca tagtttgaga ggatagccat taagcattga ccaccgctta gggcctccaa
    13321 atcaggtact aaagcctcca tcatcgtatt aacgatgttg gctcccatag cctcttgggt
    13381 atcaacgctc agatagacaa tgaaaaaatc ctccttacgc tcaacagtaa ggctctttgc
    13441 accaccacca cgcttaacaa tagaagggta ggcattgttt gcaatatcaa tcaatgtatc
    13501 tgcgttagct agaatagcca gcctagcctg ctcgtcatct ttaacatcat aaagagctac
    13561 ctgcccaagc atttgacgac tgagtacctc agtctgaaag ccacctgatc gcttgatgat
    13621 tttggcagca aaggaagcag cagcaacaac agaaggctct tcagtcacaa aggggacctg
    13681 ataggtatgc ccattgatca gaaaatcagg ggctagacta aaaggcagag ccagtcgacc
    13741 gatgacattt tcagtcattt gattggcaat agcaatgggt aagagctggt ctgtctctaa
    13801 cagcttttgc tgctgcgggc caagcagctg gtcatctgcg agctgttgaa tgcgttctgc
    13861 aaggcttttt ttataaaagc cggcccaatt tggtttagtt tttgtcatca tcttgataaa
    13921 ttcgttggtg ttccttaatt tctttgaggg caaacctgcc agttagatat ggtgaaaagc
    13981 tggcattgcc atcttggtct agtctaggct cttcataaaa aagtgcttca taatcagcca
    14041 ctgaaatcac ctgacgttgg tctaataggg cttgtcgatt agtcagtagc atgtccttgt
    14101 aaccgtcaac aagctgccct gaaaacaact cactaacagc tcctgagcca tagctaaaca
    14161 atccaatcct atcaccagcc cttagcacct gactattctc taaaagtgat aataagccga
    14221 ggtagagtga gcctgtgtaa atgttgccga tttgcttgct gtaggcaata gaagcttgaa
    14281 agttttcgta gagtttttct ttgtggttat ctgctagtag cgattttgtc atgatcttat
    14341 gaagcccctt tagagcaagc tttggaaagg ggatatgaaa acagatagca gcaaggtctg
    14401 atagctcaat gccttctttt tcttgatatt tgtcccaggt tgtttttagg gaatcaaggt
    14461 actgcttggt cgaataaata ccattgacaa atggtgttga gctgtaattt ggacgccaaa
    14521 aatccatcac atcacgtgtc tgtgcgacat tgtcatgatt taactggaga atacgaggat
    14581 tagtagtaac tagcatagca atacttccag caccttgtgt tggctctccg gcggatccaa
    14641 tgccgtattt ggcgatgtca ctggcaatga ccaagacctt ggaggctggg tgtgcagcaa
    14701 catgtaattt ggcataatct aaagcagcag tagcgctgta gcaggcttcc tttatctcaa
    14761 aggagcgtgc aaagggctga atatcaagca gctgatgaac gtaaatactg gctgcctttg
    14821 attgatcaat gcttgattcg gttgctaaaa tgaccatgtc aatgcttgct ttatcgtctt
    14881 tggtaaggat ttggtcagca gctgatgcag caagcgttac aatatcctct gtaacaggtg
    14941 caatgcttag agcgtcaagc attagcccct gatgaaattt tgctggatca gtgctgcgag
    15001 caagtgccag gtcttccatt tttaagacgt attgactggt cgcaaagcca atcttatcaa
    15061 ttccgatgtt cataaatatc cttcttttat ccattttata gtcctatcca ttttatcata
    15121 ttttcttaga aaattagctg atttaatacg atagttttat ctttcaaacc aaaaacagca
    15181 gcatatagct ttcttctggt atttttgaag gaaattagat aaaataatat gaactgtgct
    15241 tacagaaagg ggtttccatg acaaaagcag atcagatttt taaagctaat atcaaaaaaa
    15301 ttatggagga gggagtcttt agcgagcagg ctcgcccaag gtataaaaat ggtcaaacag
    15361 ccaattccaa gtacattaca ggtgcttttg cagagtatga tttgtctaaa ggagaatttc
    15421 ctattacgac cctaagacca atccctatta agtcagctat taaagagcta ttttggattt
    15481 atcaggatca atcaaacagc cttgatgttt tagaaaacaa atacaacgtt cactattgga
    15541 atgagtggga ggtcggtcag acaagaacca tcggtcagcg ctacggtgca atcgttaaaa
    15601 agcatgatat catctcaaaa atcctcaagc agctagagga caacccttgg aatcgccgaa
    15661 atgtgatttc tctgtgggat tacgaagcct ttgaagaatc agaaggactg ctaccatgtg
    15721 cctttcaggt gatgtttgat gttaggcgag tagatggtga gctgtattta gatgccacac
    15781 tgacccagcg ttcaaatgat atgctagtgg ctcatcatat caatgccatg caatatgttg
    15841 ccctgcagct aatgattgcc aagcactttg gctggagagc tggtaagttc ttttattttg
    15901 tcaataattt gcacatctat gacaaccaat ttgcgcaagc caaggagcta ttggagcgtc
    15961 agccagcagc ctgtcatccc aagcttttgc tgcatgtgcc tgatgggaca gacttttttg
    16021 atataagacc agaggatttt gagctacagg attatcaccc agtgaagcct cagcttacct
    16081 ttgacttagc gatttaggcg aaaaagacga ttttttctga gcattttgcc aagaaatttg
    16141 atagaataaa agaagttcat attgaggaaa gctagtgatg acaaagaaga ttattgccat
    16201 ttgggcagag gacgaagcag gacttatcgg aacgtgtggc aagcttcctt ggtacctacc
    16261 aaaagagctg cagcatttca aggaaacgac actgcatcaa gctatcctga tgggacgagt
    16321 aacctttgag ggcatgaagg gccgcttgtt gccaaatcgt caaacgcttg ttatgaccaa
    16381 aaacagccat taccatgtgg agggcgcttt gaccataacc agtgtgcagg aggctttgga
    16441 ttggtatcat gcgcaggata agaccctata tgtgattggt ggcagcaagg ttttagaggc
    16501 ctttgatggt cattttgatg cgatcatcaa aacagtagta catcaccggt ttgagggtga
    16561 tacctacagt cctaggttag agctgagtga ttttgtagag gagacctctg tgttgtaccc
    16621 gagagacgat aacaatcctt acgatttcac tgttacagta ttgagacatc gctaatatag
    16681 ggagatgata gtctatgcag cgtagtattt ttggggtatt tacggccttt ttgtgtgcga
    16741 tttgtgtgtt atgtgctata ccagccttta gaaaaaatcg ctatggctta ggattgcttt
    16801 ttttattaaa tgcctttact aacctggtga ataccataca tgccttttat ggaacactgt
    16861 tttaagctta agagaatgaa aagagaaaga tagaggaatc atggcaggaa atcgtagtaa
    16921 cgatattaag gttcattgct cgttttgcgg caagagccaa gacgaagtga aaaaaattat
    16981 tgcaggcaat aacgtcttta tttgtaacga atgtgttgcc ttatcacaag aaatcatcaa
    17041 ggaagaattg gcagaagagg ttctcgctga tctgactgag gtaccaaagc caaaagagct
    17101 ccttgatatt ttaaaccaat acgtcattgg tcaggagcgt gctaagagag ccttatcagt
    17161 tgcagtttat aatcattaca agaggatttc atttactgag agtcgtgacg atgatgatgt
    17221 ggatttgcaa aagtcaaaca ttctgatgat tggaccaaca ggctcaggta agaccttttt
    17281 agcccagact ctggctaaga gccttaatgt tccatttgct attgctgatg caacctcttt
    17341 gactgaagca ggttatgtcg gagaggatgt ggaaaatatc cttctgaaat taattcaagc
    17401 cgctgattac aatgttgaac gtgcagagcg tggcattatt tatgttgatg aaattgataa
    17461 aatcgctaaa aaaggtgaga atgtctctat cactcgtgat gtatcaggag aaggtgtcca
    17521 acaagccttg ctaaaaatta ttgagggaac ggttgctagt gttccaccgc aaggtggtcg
    17581 taagcaccca aaccaagaga tgatacagat tgataccaaa aatatcttgt ttatcgtcgg
    17641 aggcgccttt gatggtatcg aagagattgt caagcagcgc ttgggggaaa agatcattgg
    17701 ctttgggcaa aatagtcgaa agattgatga caatgcctcc tatatgcagg agatcattgc
    17761 tgaggatatt caaaaatttg gtctgattcc cgaatttatt ggacgcttgc ctgttgtagc
    17821 agcgcttgag cagcttaata ctgaggattt gattcgtatt ttaacagagc ctagaaatgc
    17881 tcttgtgaag caatatcaag ccttattgtc atatgatggc gtagagcttg agtttgaaaa
    17941 gggtgctctg gaggctattg caggcagggc tattgagcgc aagactggtg cacgtggtct
    18001 gaggtctatt atcgaagaaa ccatgctgga tatcatgttt gaggtgccaa gccaagagga
    18061 agtaaccaag gtacgcatta ctaaggaagc tgtcgagggc caatcaaagc ccgttttaga
    18121 gatagcctag ggaggtatga tgtctgaaga gcaaatcctt aacacgcata atgcttcgat
    18181 attgcttagt gcggcaaata agtctcatta cccacaagac gaccttcctg agattgcttt
    18241 ggcaggtcgg tcaaatgttg gaaaatcaag ctttatcaat actatactag gacgtaaaag
    18301 ccttgctaga acctcaagca agcctggtaa aactcagctt cttaattttt ttaacgttga
    18361 tgataagcta aggcttgttg acgttcctgg ctatggttat gctaaggtat ctaaggcaga
    18421 gcgggctaga tggggaaaga tgatcgaaga gtacctgacc acacgacaaa atctcagagc
    18481 agttgttagt ctggttgatt ttcgccatga gccgtcacag gacgatattc agatgtatga
    18541 gtttttgaag tattatgaga ttccggtgat tattgtggct acaaaggcag acaaggttcc
    18601 tcgtggtcgc tggaataagc atgagtctat ggttaaaaag tccttaaact ttgatcaaac
    18661 agatgcgttt attatttttt catctgttga gcgtatcggt atcgatgagt cttgggatac
    18721 cattttagag tatttataag catatggtaa aaaatttaag tatcttttag acaggcactt
    18781 gtgtctggtc tgagaggtgc ttttttattg acaaaaaaac aatttgttga tgacgagctt
    18841 gtgttcaaaa atgtcagttt gctaaaaaat gatgataaca aacaagactt ttatgatata
    18901 atgcttagca ggataatatg gagacatgag aaaaaggtca gagacagcta atttgctatc
    18961 cctgattata actatgatga ccagcattat tataatactc atggtgctag ccattagtag
    19021 cagcacctaa cctatagcgt tgctttttag gttacaagca ctagcgctag gagtattata
    19081 atatatttag aaaggttttt ttatgacaat aaaaaaatgc cctcaaatac ttgccctatc
    19141 ccttgctctt gcagcgctag ctagtcaggc gcaagccgtc catgctctag agcagcagga
    19201 gatatcggtc aagcaggctc aggaatcgag cgattggttt aatgaggacg aagattttag
    19261 agctgtcaag tctaatacct ctacagagat agactcaaca gtgacagatt tatttggtga
    19321 cgctgagtct aagactaagg ctggaaaaga agagctaaaa gcaccaagct ctaagcaaga
    19381 agcactgccg gcagagcctc aaaaagaaaa ggagacatct gccaaaccga ctgaccatgc
    19441 gacagcacaa gtggaagagg cacagcctga gcaggactca gataatcctt ggctagcaga
    19501 tgactttgtt actaagggag ataccttggt tgggctgtct aaggcaggtc ttgctaagtt
    19561 atcaaagaca cctgtcctga cactaccaag gataggtgct gacaagacag tgttgacaag
    19621 gattgctagc tttgccttta ctccaaataa atcagtagct attgctgatt atacaggcag
    19681 agcaggtgaa catggcgaga tcaatcatct ggacgtcgaa ggcaggaata ttcttactga
    19741 gggagaggat tttggtgcct atgcgattaa aaagcttgtg attcctgaag gctatctttt
    19801 tatcggccaa gatgccttta atgacaataa acagctagaa gaaatcagtc tagctgacag
    19861 cttactcagt atttcagatt atgcctttgc tcacatgagc ctgtctaagc ttaagctgcc
    19921 aaaaagccta cagtccattg gagatcaagc cttttttgat aatcggattg caggcacttt
    19981 ggtattgcca aaagctctaa agcagctggg agaacgcgcc tttaagtcca atcgtctcac
    20041 tggacttgtc tttgaaggag aaggcttgtc tgtcctaaaa gaagcagcct ttcaagataa
    20101 tgctttcatt agtcttgtta tcccagatag cattcaagcc ttagaagagg acgtctttac
    20161 aggaaacctt ggcgatgaag aatacggtaa tcatgtcgtt ttacgaacca aaagtggtca
    20221 gaatccttac agacttcaca gtgccaatgt tcttgtcaat ccaagtgatc aggctagaac
    20281 accacagcca ccaattgatt acaacaagtg gctcgcagaa gattttacct atactggaca
    20341 gatgataact ggcttttcag ctagtgggct gcgtaaggtc aaacgaaata agcatctagt
    20401 tctgcctaag gactatcaag ggcagccctt gacagccatt gcagataatg cctttagaaa
    20461 tgtcgatttt catgataaag ccttgcgtaa atacgaccta gaaagagtga cgctaccatc
    20521 taccattcaa aagattggtg cctttgcctt tcagtcaaat aatctagaaa gctttgaggc
    20581 cagcgaggac ttagttgaca ttggtcaagg tgcttttatg aataatcgca ttgagatcct
    20641 gaccttgaat gataagctga gggtcattgg agatgcggcc tttcatatca atcgaattta
    20701 tgctattgtt atccctgaat cggtcgaagt aattggcatt tctgccttta ggcaaaatgg
    20761 tgctaaacat gtggtgttta tgggagataa gctaacaagc attggagaaa tggctttttt
    20821 aagcaatact ctagaggagg tggatttgag cagcttagca gggcttaaga ccatcgctgt
    20881 tcaagccttt gcagacaatc acttgagaga gcttaagctg ccagataatc tgattcgtat
    20941 tcaagcagaa gcctttaaag ctaataggct tcaaggagtg actgttccag acactgttat
    21001 tagcattagc tttaatgcct ttgataataa tagtgatgac aaggtgatcc taaggaccat
    21061 caaccacaat aaaaacctgc tagctgacgg ggatggcttt attgtggatc cagacctatt
    21121 aagtgcggat caatcatctg ttcaagcagt tttagaggac ctgcagcgct tagatctagc
    21181 tagtctacgt gctgatacag cagctcattt tacaacactc atcacaagag gtaagcagct
    21241 actaaaagaa tccgctgtac ggttaggtta tcagcttagg ttccttgcag agtcacgatt
    21301 tttcttaggg cgcgtgagac tggatcagct gattaaatct gctgatatag ccctgtctaa
    21361 ccatcaagac acacctaatg ctaagctgtt gatggctaag ctagacaagg ccaagctgca
    21421 ttacaataat agcgcaatga ctgctcctaa aataagtcgc ttggaaaaag agctcagcct
    21481 gttaattgat cttgtccaag gggtaggcgc tatctctaaa gcaacaatga ctcaaggtgt
    21541 ctataagctt cagacaaccc tacctattcc agagtattat attggggtta atctttatac
    21601 tgatgatcag gggaatattt tatttgtgct tgacatgagt gatacgattg ggcagggaca
    21661 acttgatgac tatggcaatc ctattttaaa tgttgatgag gataatgaag gctaccatgc
    21721 tttggccatt gagtccttag cagattacga aggccttacg attaaggata tattgaccaa
    21781 ggagctaaat caattgccta ttcgcgatgt caagcaagca agagagcatc gtgttggtct
    21841 ttttatggca atcagagatg ctgcaaggga agctcagctt ctactagaaa agcagagcaa
    21901 agccttatca gaatcagccg gcaaatctaa tggctcaaaa gtagctgact caggacttga
    21961 gccttctgtg acactatcaa ccaataagac taagaagctg ttaccaaaaa caggagcctt
    22021 caaagaagct tgggtgacaa tgatcggaat gcttgttctt ttggcggctg ccctacttaa
    22081 aggcgatagt cgctacaaaa aaagaagtaa ataggcttgc ttagcaagta cactccagca
    22141 ccagtgagac ttgatgcgct taaaaagcct atctaatcta gcgatagtat tttgccagtg
    22201 tgggctgggg cttgagcttc aaaaaccaaa aagcctgaaa tgacttttac tagcatttca
    22261 ggcttttttt agcttgtgat tcttttttgt gtgaagctta cttctcactt atcgtaatag
    22321 tatcttgatc aaggcttgct aataggtgtt tagcagtcgg gtgatccagg tagtaatccg
    22381 taatgcggtc acgaatttct tgttcgatga cacgtctaag tggacgaact cccattgcat
    22441 gatcatagcc cagatcaatc aaacgctctt taacatcgtc agtcacctca aggctaatcc
    22501 cttttttagc aagggtttgg ttcacctctg ctagcattaa agcaacgatt tcttgtagat
    22561 cctttttcgc taaatggttg aattcgatga caccgttgaa gcgattcaag aattctggtc
    22621 taaagtaagg tgcaatacgc tccatgatag caggctcttg atcagcacta tctcctgctt
    22681 gatggccaaa accagcatta gaggttgcga tgataaccgt atttttgaaa ttgatcgtgt
    22741 tgccttgtcc atctgtcaat cgcccatcat caagcacttg aagaagcagt gtaatgacct
    22801 gtgggtctgc tttttcgatt tcatcaagca agatgataga gtaaggactg cgacggacac
    22861 gttctgtaag ggtattttga ttatcatcat agccaacata gccagctgtt gttccgatta
    22921 atttggaaac agctgtgcgg tcactatatt cagacatatc taagcgaatg atagcgtcct
    22981 ttgagccgaa catatcaagg gctaactgct tagccagctc ggtcttacca acaccagttg
    23041 ggccaacaaa gaggaaggag ccaattgggc gattaccgtc atcaaagcct gcgcggttgc
    23101 gtcgaatcgc acgagcaaca gcctcaactg caccatcttg tccgataaca tggcctttaa
    23161 gacgattact gatttctttg agcctttcta aatcattagc ccccatattt gagactggga
    23221 caccagttag tcgttcaaca gattctgcaa tatcattgac ggtggcagtg accttttgcc
    23281 cttcactgtg atgattgatt tgcttttgaa gctcctcaat gcgtgtctta gcagttaagg
    23341 ccttttcaaa gtcttcttct gcaacagcct tttcctgtag ctccttttgc ttagcgattt
    23401 ctgcttcaag tgactttaga tcagtgacag ggtgctgagc tgctaggtgg gcagccgtca
    23461 tatcaacaag gtcaatggct ttatcaggca ggcttcgttg tggaatatat tggatagcat
    23521 aatcaatagc tgccttcaag acagagtctg gtaggatcac attgtggtgc tgctcgtaga
    23581 ggttgcgaat gcccattaaa atgtggaagg tatcctctgc tgaaggagca ttaaccttaa
    23641 cctcgttgaa acgacgagca agggcagcat tttttaaaat agtattgcga tactcatctt
    23701 gagttgtggc accaatcaag gtcaactcac cgcgtgagag agctggcttt agaatatcag
    23761 ccaagccctt agagcctgag tctgaaccag ctgaccctgc accaaggatt tgatgaattt
    23821 cgtcaaagaa gagaatgata ttgccagcct ccttaacctc tttaaccatg ttttgaatgt
    23881 tttcttcaaa agagccacga tactgtgtgc cagcctcaag gccagaaata tcaattgaga
    23941 taatctcttt atttttgatg gcagctggca catcaccgtt gacaatagcc tgggctaggc
    24001 cttcgacaac agcagtttta ccaacaccag cgtcaccgac aagaacaggg ttattcttgg
    24061 ttcgtcttgc tagaatttct gcggtcgctt gaatctcatc gtttcgtccg atcacaggat
    24121 ctaacctgcc ttgccgagct tcttcggtca ggtttgttcc gagcttggtt agaatgccgt
    24181 cttttttaag gctgctagcc tgtttttctt gtccctcagc tacagctagc ttaccggttt
    24241 tccggtattc ttgaaattcc tctggtgtca tctcacgtcc attgacaaga tagcgacgat
    24301 tttcgctgcg gtagccgccg atgtttccca ttaattgatt aaaaatatcg tccatatttc
    24361 caaaggggtc ttttccataa taggttgcca tatacactta cctcacttgt attatattta
    24421 ccagtcatta tgagctactg gtataggtag aaggtgatcg gtgttggctc atacagagat
    24481 catagagagg tcttatgaga gtctattgct caggcttatt actcaccttc taataatatt
    24541 atatccaaaa ggtcagtaaa ggtcaaataa aaagtatgaa taattaacct ttataatcag
    24601 gtgcttatag cccttgaaac atcagatgac tatgccataa gctgctggtg cttttttgct
    24661 agcaaggcta tctgtaaaga agagactttt gtcaaaaatg gttttacttt ttgttctaaa
    24721 ggctttcatg atataataaa agaaaagcac agaggtcaat tatggaacaa acatttttta
    24781 tggtgaagcc tgatggtgtg aaacgtggct tggttggaga gattctacgc cggattgagc
    24841 gtcgtggctt tacctttgat aggcttgaat tgcgacaggc aactccagaa ttgctagcca
    24901 agcattatga cgccttaatc aataagccct tttatccaga gctagaggcc tatatgacaa
    24961 gcggacctgt tttaatcggc attatctccg gtaatcgtgt ggtctcttcc tggcgaacca
    25021 tgatgggggt gactaatcct aaggacgctt taccggggac tattcgtggt gattttgctc
    25081 aagcccctgg tgatgatggc ggcattttta acgtggtgca tggttcggat tcgagagatt
    25141 cagctaagcg agaaattgcg atctggtttg gacatagctg acattgggct tgggtctatt
    25201 cttttaagaa ctgataaagc aattgcataa ggggttggta aagcccatca tcaatagtag
    25261 ctcagcatta gaagggtaac agccttgatg ttgggctatt tttttgcttg cctagggttt
    25321 atatgcttgt cctgatgagc aggtagacaa agcagcataa gtttaacaat cctttgcggc
    25381 agtgatcaat tgtagctcta accatagcat cagctatttg aaagccttga aaaagaaagc
    25441 taaggctaac aagctagtct aggtcattta ctacaagcga ctttttcaat tagctgctca
    25501 aggcaagtat tgaaaaaagt ccatttttca tgtcatttgt aataatatgg tatattttta
    25561 acgaaaagtc gttttagttg agaaaatata caaaaaaggc tatgatatag ttaataaagt
    25621 tgttataccc cctgtgtctt gtacactatg acttgtagag agtttatcaa aggaggataa
    25681 gatgaacaaa caaagcatga cccatttttc taagaagctg atgaagctag cccttttagg
    25741 cttggcattg ccattaagct tggtgtcggt ggcagatact ccggttctta accgatccga
    25801 aaaagctgtt tatgccaatg attttggatc tggaaatcga gccagtgatt atgtaccggc
    25861 ggctaaggct tggagctttg aggcttatcc agattactac cgcgttttag gggctagtca
    25921 tcttaatcct gcaatctttc cagaagctgg caacatgtcc tatagtccct tagatgaatt
    25981 gggacgtaca caggtcgcca gaggaacaat aaattatcac aatattgtga tgaactacaa
    26041 tgttagacag cgctttgcta aaaatcagaa cccttcaggc tggattggta accctagaaa
    26101 tgttcgctac actattgagt ggctagatgg cctatcctat cagggagatt tttggaatcg
    26161 gagtcatttg attgcagata gccttggtgg agcagcctta cgtgtcaatg cgattactgg
    26221 tacaagaaca caaaatgttg gcggcagaaa tcaaagaggc ggtatgcgct atattgagca
    26281 gaaggtgcag cagtggattg agcagcatac aagcgcagtt gtttattacg aagcgatgcc
    26341 aatttatcag gcaaatgagc tagttccaag agctgttgtt gtttcagcat tgtcatcaga
    26401 cggaggtctt gacgaaaagg tcatggtcta taataccgcc aacggctata ccatcaatta
    26461 tgctactgga gcatttcaaa gtaattaggc ttttgtacta agctgtagct gatcaaggtc
    26521 tgactaagac aagtgcatca gcaattgata tataaaaaga catgacagca gctgttttaa
    26581 atgccttgtc atgtcttttt agtcttgtca gcttttcatg ttgtcttaaa atgaccactc
    26641 aactaactac aagcattgac ccaaagaaga gttaaggata gctaggtgct aaagctagct
    26701 aggtgccttt tagtcagagg tatgggactg ctagctaata taatgcccgc agttgagcca
    26761 atttctcatc taggctaata caggctattg acttatagtg ttcattagaa tgtcagctgt
    26821 tgtagttggt agtattcgaa tacgattaag cgatagcagg ccattagcag cacttgctag
    26881 tccttcattt gttgtgaccc ctaacttgta atgcaggtcc tcagcaatct ttaatgtggt
    26941 atcagtatag cgacctgctg gataggcaat tgcaatcgta tcttggtgca gctctctatc
    27001 taggtattct ttagaatcct tcatttcagc ggtttgacta gcagcgcttg cctgagatag
    27061 atcagggtgg ttaaccgtat gatcttggaa agacatgcct gcctgcttca tttccttcat
    27121 ctggtctaat gtaagattgg ctgcattacc tgcctctgta aagccagtga tgacgttatt
    27181 ggtggccttg atgccatgct ttttcaggat tggaaaagca acgttgtaaa aatcaaccat
    27241 gctatcatca aaggttagcc agacaacctt ttcagcagga agttcgttag ctgataagac
    27301 tcggtaggct tcttcgggag ataaaaagta gtagccggcc tccttcattg cctttagctg
    27361 gctttcaaaa agatctggag caacgatgag attagcactt gctgcctctt ctggtgccat
    27421 aacgtgaata gcatgataca ttaaaatagg aagcttaaca ggggcttgct gcttggtcca
    27481 gctgacagct cctttttgct gctgactatc tgtatggcta gctttcttat tatttgcttt
    27541 tttgctgggc ttgggagctg gctttttatc agtttttgaa aataggctta tttttgggat
    27601 tgcctgcgat aattgagaga tgcttatctt tgaatggctc ttgtaaaggt agacaatagc
    27661 tgataagcct atgatacagg cgagtagtag catgagatta atcattttga aaatttttct
    27721 ttttttacgc cgtttgtttc tgttgttcat cacttgctcc ttgtttattt attagtctat
    27781 tgtaacattt ttttaagcaa gctgtctttc gttaacttaa ttttttgcta acattctatt
    27841 agtgttatgc tttgtaaaat aagactaaga tttgctataa taagacagag tatttaaggc
    27901 agtcaaaaaa ggaggataga atgtcagtta agattgcatt attaggcttt gggactgttg
    27961 ctagtggcat tcccttgcta ttagagaata atagtagcaa gattcgtgca gtggtaggtg
    28021 atgatttggt gattgcaaag gttctggtta gagatgagat cactaagaag catttgttgg
    28081 atcaaggcta ttcctaccaa tttgtgacct ccattgatga tattgttgac gatgagagca
    28141 ttgatatggt agtcgaatta atgggtcgta tcgagcctgc aaagaccttt atttcgcgcg
    28201 ctctatcagc tggaaagcct gttgtgactg ctaataagga tttgatagcc ttgtacggag
    28261 gagatctctt gactttggca gctaagcatc aggtagcttt gtactacgag gctgctgttg
    28321 ctggtggtat tccaatacta agagctttgg ctgattcctt tacctcagat aagctgacgc
    28381 gtctgctcgg tgtgctcaat ggaacaacta atttcatgtt aaccaagatg attgatgaag
    28441 gctggaccta tgaaatggct ctgcaaaaag cgcaggagct gggctatgct gagagtgatc
    28501 cgactaatga tgtgaaaggg atcgatgcag cttacaaggt tgctattctt agtcagtttg
    28561 cttttggagt gaccattgac tttgaggcta ttagctattc agggattgat aagattcgag
    28621 tagaagatgt gacagtagcg cagaagctgg gctatgtgat caaattagtt ggcctgcttg
    28681 aagagacggc ttctgggctt aacgcagagg tatccccagt ctttttacca aagacacacc
    28741 cgttggctgc tgtagacggt gtgatgaatg ctgtttatat cgaatcaatt ggggttgggc
    28801 aggctatgtt ttatggtcca ggtgccggtc aaatgccaac agccacagct gttgtggcag
    28861 atatgattca gactgcctgc accttacgtg accatacagt ctcagtcttt aatcgttttg
    28921 ctacaaaaac tagactagct aagtctgagg atattgtgag tccctattac tttgctattc
    28981 aagcaactaa taagtttggt cagctactag agctaacaag gctatgtgat gcttgtggca
    29041 ttaagattga ggagctgtta tcaaatgaga caggcagtga caggctagat tttgtgatga
    29101 ttactcatga gatgagcaaa aaggagcttg cttgctttac agcgctacta caggaccatc
    29161 aggatttccg tatgttaagt acatttaaga ttttaggaga ttgacatgaa gatacgcgta
    29221 cctgcaacct cggctaattt gggacctgga tttgactcaa tggggattgc tgtttcaaaa
    29281 tatctagaag ttgacatttt agaagaacgt gatcaatggt ttattgagca tgatttgggt
    29341 gatattccaa atgatgatag caacttactc atccaaacag cccttaggct agcaccaaat
    29401 attccagcac atcgtctaaa gatgacgtct gatattccat tggcacgtgg cttgggatcg
    29461 tcctcctcgg tgattgtcgc tggtattgaa ttagctaacc agctggggca tttaaaccta
    29521 acagctgatc gtaaattagc catagcaact cgtattgagg ggcaccctga taatgtagct
    29581 ccagcgattt ttggtcaatt ggtgattgct tcacagattg gtaaggacgt ggattatatc
    29641 attgcgcctt ttcctgacct ttctttggtt tgttttattc ctgattatga attgaaaacc
    29701 tctgattcca gagatgtatt gcccaagcag ctatcgtata agcaggcagt ggctgcttcc
    29761 tcagttgcta atcttgctat agctgcgcta ttgaccggta atttgaaaaa ggccggtcgg
    29821 gcgattgaaa atgaccaatt ccatgaaatc taccggcaaa gattagtcag agagttccag
    29881 ccgattaagc gagctgcagc agctaatggt gcttatgcaa cctacttatc cggtgcaggg
    29941 cctgctatta tggttatgtg ccccaatgag agaaaaatgg caatctatga cgcgatcgat
    30001 cagctaggtc taaccggtca gttggtgtct ctagagctgg atcgtcaagg gctatgtctt
    30061 gtctagactg gcaaggtact ggtatgcttg cctagtaggc ttattgttga tatcagatgg
    30121 acttaaagct tagtcattca aatacatcaa aaaagtgagg tctgatcgtt ttatcggctt
    30181 tcactttttt cttgatatgt tatactagag tagactttgt gaggtgtgtg atgaattatc
    30241 aagaaacatt agactggatt catggtcagg aaagatttgg gatcaagcca ggtgtaaaac
    30301 gcatgcgttg ggtgcttgag cagctaggta atcctcagga taggattaaa ggaatccatg
    30361 tggtcggtac aaatggtaag ggatcgacgg tcaatgacct acagcatatt tttactagag
    30421 caggctatga ggttggaacc tttacctcgc cttatatcat ggattttaag gaacgtatct
    30481 gtctcaatgg tgagatgatc tcagagactg accttgttaa ggctgctaat cgtattcgtc
    30541 cactaacgga tcgccttgtc agtgagacaa gcctgggtcc tgcaacagtc tttgagctga
    30601 tcactctgat catgtttctt tattttggtg agagtcaccc ggttgatatt gctattatcg
    30661 aggcaggatt aggggggctt tatgactcca ctaatgtgtt tcaggcgatg gctgtggttt
    30721 gcccgtctat tggtcttgat catcaagcta ttttaggtga tacctatgct gacattgcct
    30781 atcaaaaagc cggtgtgcta aaaggtggtg aagaccttat ttttgccatt gataacaaag
    30841 aggccagaca ggtttttcta aaaaaagcag agcagcttgg cgtgcctatt tgggaatggc
    30901 gtcgacagtt caacatgcta caaggtgaag gcggttatca atttaacagt cagcttggtc
    30961 agctgtctca tctagtgctt gcaatgcctg gtcagcatca ggtagccaat gcaggcctag
    31021 ccactatgac aagcttgata ttacaggatc ggtacccaaa ggtaactgag tctgttatta
    31081 gagaggctct ggcaagcagc ttttggttgg gacgaacaga attgttggca cccaacctga
    31141 tgattgatgg tgctcataat aatgaaagca ttgctgcttt gattgatgtg atatcatcag
    31201 actatcagga taagcagatt catattctat ttggtgccat tgataccaag cctgtctcag
    31261 atatgctaca gagtctggag cgtcttggag atgtgcaggt aacaagcttt aactatccca
    31321 atgcctatcc tttggaggct tatccagata ggctaacaaa agtagcagat tttagagcat
    31381 ttttagaccg gcttgagcaa gcagctgctg atgatttttt cctgattaca ggctctcttt
    31441 acttcatctc agaggtcagg cagtattgga aaaaggtatt aagcaagtaa tgctttctca
    31501 catcaactca tcaaacaaga ttaatcaact aaaaagggga aaaccattgc caatcaatca
    31561 aaaaaaagca gaagcagcta tctatcaatt attagaagct atcggtgagg atccaaaccg
    31621 agaagggcta cgagataccc caaagcgtgt tgccaagatg tatttggaga tgctctcagg
    31681 gctggaacag gacgctaagg atgaatttac agctgttttt acagagcatc acgacgattt
    31741 ggtgattgtt aaggatatta gcttttattc catgtgtgag caccatctgg tgccatttta
    31801 cggtaaggcg catattgctt atttgcctag tgatgggcgt gtgaccggct tgagtaagct
    31861 ggcaagggca gttgaggtga cgagcagaag acctcagctg caggagcgtc tgacagctca
    31921 gattgctaat gctcttgttg atgccttgca gcccaaaggg gtttttgtta tggtagaagc
    31981 agagcatatg tgcatgacca tgcgaggtgt caaaaagcca ggcagtaaga ccattacgac
    32041 aactgctaga gggatttaca aggacagtag agacgacagg cgtgaggtta tgcaattaat
    32101 catggagggc tagggtattt atgactattg gacattattc agccgctggt gaggcagcta
    32161 ttatggggat tttaaatgtg actccggatt cgttttcaga tggtggctcc tatactagtg
    32221 ttaatcaggc cttggcacag gccgaaaaaa tgctgtcaga aggagcgact gtcattgata
    32281 ttggaggcga gtcaacacga ccgggctgcc aatttgtgcc ggcagaagaa gagattgcac
    32341 gcgttgttcc aatcataaag gccattaaaa aacggtatga tgtccttatt agcattgata
    32401 cctacaagac agaaactgct agagcggccc ttgaagcagg agcagatatg ctcaatgatg
    32461 tctgggcagg actatatgac ggtcaaatgc taagtctagc taccgaatac gacgttccta
    32521 ttatactaat gcataatcag accgaagagg cttatgctga tgttacaaaa gaggtttgca
    32581 gctttttaca ggctagagca gctgcagccc tcaaagcagg tgtcaaaaaa gaacatatct
    32641 ggcttgatcc aggatttggc tttgctaaaa atgttgagca aaatatagcc ttattaaagg
    32701 ggctgagtga ggtttgtcag ctaggctatc ctgttctttt tgggatttcc agaaagcgcg
    32761 ttgtagacgc cctacttggt ggcggcacta aagccaagga tcgtgacggg gctactgccg
    32821 ccctatcagc ctacgctatt aataagggct gtcaaatggt gcgcgtgcat aatgttggtg
    32881 ctaacaggga tattgtctct gtattgagtc aattaaggtg aggaatgatg gataaaatca
    32941 gattagaggc ctgtcgcttt tacggttatc atggtgcctt tgaggaggag caggtcttag
    33001 gtcaaatttt tgtagtggat ttagaattat cagttgactt gatggctgcc tctctttcag
    33061 actgcctaga ggatactgtt cattatggtt tagtttttga aacggtacgt caaatcgttg
    33121 aggaaaagac ctttacgctt atcgaacgtc tggctggtgc catttgtcaa gagctatttg
    33181 accagttttt gcctattaaa gcgattaaaa tcgctattaa aaaagaaaat ccaccgattg
    33241 caggccatta tcaagctgtc ggtattgaat tggagagaaa gagatgacac ttgtttattt
    33301 aggcttggga acgaatatgg gagatagagc aggctaccta aaggcagcag ttgctgccct
    33361 atctaagcta ccagatactg agttactgag acaatcctct atctacgaaa ctgcagcctg
    33421 gggaaaaaca gatcaaaatg cctttttgaa tatggcttgc cagctagata ctaggctgac
    33481 atcagaagct cttttggcag ctacgcaggc tatcgagcag gctctgggac gagttcgtca
    33541 tgaaaaatgg ggcccaagga caattgatat tgacctcttg ctgtttggtg atgagttgta
    33601 tcaatcagag accttggtta ttcctcaccc ttacatgaca caaagagcct ttgttttgat
    33661 tcctttatta gagattgcac ccgatgtgac cttacctggt agccagaaaa gcctgaggtc
    33721 ttaccttgat gctttagagc aatcagatgt agccttgtgg tcacatgagt attcaaataa
    33781 gttttcttaa actgtcgtta tttttactaa aatttgatat aatagtgcta ctctttgctg
    33841 attttttgtc ttatattaag aaatgattga agaaagaaga agattatgat agctgaactt
    33901 gaaggcattg atattcgaga gaatgaagcc ttaaaacatt acacctatac ccaagtaggc
    33961 ggtccagcag atttcttggc ttttcctaga aatcattacg aactatcccg tattgttgat
    34021 tatgccaatc acaatcatat tccttggatg gtccttggaa atgccagtaa tctcattgtc
    34081 cgagacggtg gtattcgtgg ctttgttatc atgtttgata agctcaacgc tgtccgcctt
    34141 aatggttata ccttggaggc agaggcaggt gccaacctca ttgaaacaac aaaagttgcc
    34201 aaatttcata gcttaacagg ctttgaattt gcttgtggca ttcctggaag catagggggt
    34261 gctgttttta tgaatgcagg tgcttatggt ggagagattg ctcatatttt tttgtcggcc
    34321 aaggtcttga caccagaagg gaaaataaaa aagatctcag caagagagat ggcctttggc
    34381 tatcgtcact ctgtcattca agaaactggt gacattgtga tttcagccaa gtttgcttta
    34441 aaaccgggta atcatgacag tatttgtcag gagatgaatc gcctcaacca ccttcgaaag
    34501 ctcaagcagc ccttagaatt tccctcttgt gggtccgttt ttaaacgtcc tcctgggcat
    34561 tttgcagggc aattgattat ggacgctaac ctaaaagggc atcgtgttgg cggtgttgag
    34621 gtctctaaaa agcatgcagg ctttatgatt aatgttgctg atggctctgc caaggattat
    34681 gaggacttaa ttgctcatgt tattaagaca gttgagcaga cctctggtgt taggcttgag
    34741 ccagaggttc gtattattgg tgaaagcctt taatgattgt gttatcaaaa aagaaaaatt
    34801 gtggaggatt tatgacaatt gactaagcca attatcacat ttgacaatgt ctcaaagaca
    34861 tttgaggaca gcggaacaca ggttctaaag aacattaatt ttgagcttga ggagggaaaa
    34921 ttttacaccc tgcttggtgc ctcaggatct gggaaatcaa ccattttaaa tattatggct
    34981 gggctgcttg atgcgaccag tggcgatatt tatttagatg gtaagcgtat caatgatttg
    35041 ccgaccaata agcgtgatat tcacactgtt tttcagaatt atgctttgtt tcctcatatg
    35101 acggtttttg agaacgttgc ctttgcttta aagctgaaaa aggttgacaa acaggagata
    35161 gcaagacgtg tcaaggaaac cttaaaaatg gttcaattag aaggctacga aaagcgatcc
    35221 attcagaagc tttctggtgg ccagcgtcag cgcgtggcaa ttgctcgtgc gattatcaat
    35281 cagcctcgtc ttgtcctatt agatgagcca ctttctgccc ttgatttgaa attgagaaca
    35341 gaaatgcagt atgagctgcg tgagctgcag cagcgactgg gcattacctt tgtttttgtt
    35401 acccatgatc aggaagaagc actagccatg agtgattgga tttttgtcat gaatgatggt
    35461 gaaattgtgc aatcaggcac acctgtcgat atttacgatg agccgattaa ccattttgta
    35521 gccagcttta ttggtgaatc aaacatcatc aatggcacga tgattaaaga ctaccttgtc
    35581 tcctttaatg gaaaggaatt tgaatccgtt gatggcggta tgcgaccaaa tgagccagtt
    35641 gaggtggtta ttcgaccgga ggatttacaa atcaccttgc cagaggaagg aaagcttcag
    35701 gtaaaggtag atacacagct ctttcgtggt gttcactatg aaatcatcgc ctatgatgat
    35761 ttaggcaatg aatggatgat tcactcaacc cgtaaggcta ttgagggcga ggtgattggc
    35821 ttagacttca caccagagga cattcacatc atgcgtctca atgaaacaga agaagaattt
    35881 gatgctcgta tcgaagaata cgtcgaaata gatgagcatg aggatggcct aatcaatgct
    35941 attgaggagg agcgcaatga agaaaacctc tagcctcttt gcagttccct attttttatg
    36001 gattgtcctc tttgttatgg caccggttgc ccttttgctt tatcaatcct tttttgacat
    36061 cgaaggacga ttgacactag ccaattacga gacttttttt agctcatgga cttacctgag
    36121 aatgggctta aactctatct tatatgctgg tatcgttacc ttggtgacct ttttgatttc
    36181 atatcccaca gctttattgt taacgcgttt aaagcacaag cagctgtggt taatgcttat
    36241 tattttacca acctgggtca atctgctcct caaggcttat gcttttatgg ggatttttgg
    36301 gcagcagggt ggtatcaata gctttttaac ctttatgggc ttaggaccac agcaaattct
    36361 gtttactgat ttttcgttta tttttgtggc ctcttatatt gagctgccct ttatgatttt
    36421 gcctattttt aatgctttag atgatattga tgataatatt atcaatgcca gtaaggacct
    36481 gggtgccaat gactatcaga ccttttcaag ggttatcttt cctttgtcgc taaacggtgt
    36541 tagagcaggg gttcagtctg tttttattcc cagcttgagt ctctttatgc ttacgcgtct
    36601 catcggtgga aatcgtgtga ttacgctggg gacagctatt gaacagcatt tcctaacaac
    36661 agaaaactgg ggaatgggct caaccatagg tgttgtccta attatcgcga tgattgtgat
    36721 tatgtggcta acaaaggaga aaagtaaatg aaaaaatttg ccaatcttta cttagcgtgt
    36781 gtttttattt tgctctatat tccaatcttt tacttgattg tttattcttt taacaagggt
    36841 ggagacatga atggcttttc tggcttgacg ctagagcatt ataagacgat gtttgatgat
    36901 agtcgcttga tggcgatttt attgcagacc tttgtgttag cctttacaag tgccttgctt
    36961 gcaaccatta tcgggacctt tggggcgatt tttattcatc agagtaaaaa gaagtaccaa
    37021 aatgcgatac tgtctgcaaa taatgtgttg atggtttccc ctgatgtgat gataggtgcc
    37081 tctttcttga ttctctttac gtccttgaaa tttcaattag gaatcctctc ggttttgatg
    37141 agtcatattg ctttttccat tccgattgtg gttttaatgg tgcttcctcg gttgaaggaa
    37201 atgaatcaag atatgattaa tgcagcctat gatctaggag caaatcattt tcaaatgcta
    37261 aaggaggtta tgcttcctta tctgacaccg ggcattatcg caggctactt tatggccttt
    37321 acttattcct tagatgattt tgcggtgacc tttttcctca caggaaatgg ctttacaacc
    37381 ctgtctgttg agatctattc gcgtgctcga aggggcattt cgttagatat caatgcctta
    37441 tcaacgattg tctttttgtt ctcgattcta ttagtcattg gctattatta catttcacag
    37501 gacaaggagg aaaagcatgc gtaagctata ttctttttta gcaggaatta ttggggttat
    37561 cttgctgctt gcgaccctgt cctttatttt gcagaaaaaa acgagctctg ctagtcaatc
    37621 tgataagctg gtgatttata actggggaga ttacattgat cccgctttgc tgaaaaaatt
    37681 caccaaggaa accggtatcg aggttcagta tgagaccttt gattccaatg aagccatgta
    37741 cactaagatc aaacaaggtg gaacaaccta tgacattgct gttccgagtg attacacgat
    37801 tgacaagatg attaaggaaa agcttcttgt taagctagat aagtccaagc ttgttggtct
    37861 agataacatt ggtcaggagt ttttaggaaa aagctttgat ccgcataatg attattccat
    37921 tccttatttt tggggaactg taggcattgt ctataatgat cagctggtgg ataaggctcc
    37981 tatgcattgg gaggatttat ggcggccaga atatcgaaac agtattatgc tggttgatgg
    38041 tgcccgcgag atactaggcg ttggattgac cacatttggc tgtagcgtta actcaaaaca
    38101 cctaaagcag cttgaagcag ctgaaaaaaa actacaggcc ttaaccccta atgtaaaagc
    38161 aatcgttgct gatgagatga aggggtatat gattcaaggt gacgctgcta ttggtgtgac
    38221 cttctcagga gaggctagtg aaatgctgga caacaacgac cacttacact atgttgtacc
    38281 atcagagggc tcaaaccttt ggtttgataa tctggtgctt cccaaaacaa tgaagcatga
    38341 aaaggaagcc tatgccttca tcaactttat catgaagccg gaaaatgcag cacaaaatgc
    38401 tgaatatatc ggctatgcca cacccaatac aaaagcgaag gctttactgc cagatgatgt
    38461 taaaaatgat ccagcctttt acccaactga tgagaccgtt aagaaattag aggtttatga
    38521 taatttaggc tctaaatggc ttggtattta caacgacctt tacctacaat ttaaaatgta
    38581 tcgaaaataa gtcatgtaag actgaaggaa ctattcattt gaaggcttcc tcagtctttt
    38641 ttagcttggt ctggtctcaa tcatctcatg agattaaaaa gaactagaat cttgcttctg
    38701 tctttgatac aatagtagtg gtttatcaaa atgaaagaga tgacaaaatg gaaaatcata
    38761 aaaacgagtt taccttttcc aaacactcaa tcatagctta cgtttggcga ggcattttag
    38821 tcggaataat tgctggagcc attgtcagtt tgtttcgctt gttgattgag atgattagcg
    38881 agaaggttat tgactattac caccaagctc atagcaatct catgctcctt gttccgatag
    38941 caggctttag catattagct gtttttttag ttggtctttt ggtcaagtct gacgccaaca
    39001 ttaaaggttc tggtattcca cacgtcgaag gggagctaaa gggcttgatg tcacccaatt
    39061 ggcggagtgt gctttggaaa aaatacctag gtggaacaat tgccatttct atgggcttaa
    39121 tgctgggaag ggaaggccct tccatacaat taggggctat gtcagctaaa ggtttagcca
    39181 agtatctgaa atctagccgt ctagaaaaac gcgtcttgat cgctagtgga gcagctgctg
    39241 ggctatcagc tgcttttaat gcgcctattg cagggctgct gtttgttgtt gaggagattt
    39301 accatcattt ttcaagatta gtgtggatca ctgccttggt tgcaagcctt gttgcgaact
    39361 ttatttcgtt gaatattttt ggccttagac ctgttttggc catgcctaag gccatgccct
    39421 ttcttgcctt aaatcaatat tggctgctct taatcttagg tcttgtactt ggctgcctgg
    39481 gctttcttta tgaaaaggtc attttacatt ttcatagggt ttatgatttt cttggaaaga
    39541 gcttgcacct agcaccgcat ttttatggac tgattgttgt tgctattatc ctgccgattg
    39601 gctattattt gccacagcta ttgggcggag gtcatggctt gattatgtcc ttgtcagagc
    39661 aaaagctacc actgttgact gttcttgcct acttctttat tcgattttta gggagtatgt
    39721 ttagctatgg cagtggcttg cctggaggaa tttttttgcc tattctaacc ttaggtgcct
    39781 tgtctggaac tatttttgga ttgacctttc agcaaatagg actgttagat caccagttga
    39841 ttcctctctt tttagtattg ggaatggcag gctactttgc tgctgtatca aaggcccctt
    39901 tgacaggaat gatcttagtg actgaaatgg taggggactt gaagccttta atggccattg
    39961 ctgttgtgac cttcgtggct tacttggtga tggatttgtt aaatggtcag cctatttatg
    40021 aagcaatgct agaaaaaatg gccatcaaac acccaacaga tctggtggag ccgaccctga
    40081 ttgaattacc tgtgagtgag aaaattgcag gtagatacgt ccgagactta aggctgccta
    40141 aaaatgtttt aattacaacg cagatccatc ataagaaatc acaggtcgtc tcaggtgata
    40201 cgctattgat ttcaggtgct acgatctttt tggtggtcaa tgaagctgat acaggctttg
    40261 ttcgagaggt tttgatgtag agcaaggacg gttagccggt tagcagtagc tgtgctatcg
    40321 atcaaagaag cagatcagtg ctttttctcg tctgatgaaa gcattgattt gcttttttgt
    40381 gtcattgagt ccggttgtag caagagacat agccttagca gtcgtatctg atgaatacct
    40441 gctgtctttt tgttatactt aagtatcaat caaaggagct ttatatgcta gaagttattt
    40501 caaaagagct gcgccattac caaaagaata agcttgccgc ctatcaaaaa aagaaccaag
    40561 gcatagaagc tggtggaatt gtttttgctg gcgattcgtt aatcgaattt ttcccgttga
    40621 aaaaatattt caaacaggtc tcaaccattt ataatcgcgg aattgcaggg atagacagtc
    40681 agtggttgct agagcatatt gacagtcatg tgaatgatct ggagcccagt catgtgttta
    40741 tcctgattgg ctgtaatgat attgggcttg gctttgatca atcgcatatc gtatcgacca
    40801 ttgttgatct tattagtcgt attcgcagcc agtctattta tactaggatt agccttctgt
    40861 ccttattgcc ggtttctgaa aatcccgcct atcaggcgac tgtcaagcta aggacaaata
    40921 gggttattga tgagattaat caagcattag caatgatacc agcgattgaa tttattgatc
    40981 ttaacgcctg cttaaaggac gagactggtg gcttagcagc tgcttatacg gtagatggca
    41041 ttcatcttaa tgcccttggc tatgaacact tagctcaagc gattagtccc tacctgtaaa
    41101 ggtaaaggct gaagctgcta atttgtaagg gatctttaaa aaccaagcac tgatgaatca
    41161 tcattgaaac ccttcagagt gccgataggc tgcacaataa aagaagcatt aggtttatac
    41221 tgcgagaaaa tcagccattg ggctagaagt ctcaaagctt agctgtagta attgggtgcg
    41281 agctactgtt agcttgtgct gatcaagtag catcgtaagg aagggctgag cctttaagct
    41341 cagataatgt tagacttttt atcctatatt aaacgattta gtgtataata aacaggaagg
    41401 agttaaaatg aaatttgaaa aaaaacaagt cttttatgtt gtgcttgcct ttgttctttg
    41461 ctatgctatt caagctaatt gggataatgg ggctaatatt gtcacaaccg tttataagac
    41521 aagcctgccc tttctttatg gagcagcagt cgcctatatt gttaatattg tcatgagtgc
    41581 ctatgaaaga gcgtatactt ataccctaaa gccctttcct tttgccatga aggctaaaag
    41641 agggctctgt atgcttttgg catattttac ctttatcagc ttgatcgtat ggattatttc
    41701 tattgtaatt cccgatttga ttgcaagcat tagttcgtta acgcaatttg atacaagagc
    41761 tatcaaggag gtcatcagtg atttaggtca caataagctg attgcgcgtg ccattaatta
    41821 cattggtgga gatgctaagc tgacagaaac aattaccaat tatagccagc agctgctcaa
    41881 gcaatttata ggtgttctaa ccggtatttt aacatcggtt acagcagttg cctcagccat
    41941 tatcaatgta gttatcagct ttgtcttttc cctgtatgtg cttgctagca aggaagagct
    42001 ttgtcagcag gcaactacct taattgacac ctatactggt aaatacgcaa aaaccgttca
    42061 ttatttagta ggtctgctgc atagtcgctt tcgtggcttc tttgtgagtc agacgcttga
    42121 agcaatgatt ttaggctcct tgactgctat tggcatgttt atcctgcaat taccctttgc
    42181 aggaactatt ggagtcttgg ttgcttttac tgccttgatc cctgttgttg gtgcttcaat
    42241 cggtgctgcg ataggctttg ttttgattat gactcagtca atgtcgcagg cagtcgtctt
    42301 tattgtcttt cttgttatac tacagcaaat cgaagggaat tttatttatc ccagagtggt
    42361 tggtgggtct atcgggttac cagctatgtg ggtcttaatg gcaatcacca ttggtgctgc
    42421 tctcaaaggc attgttggta tgatcgttgc agtgccatta gcggcaacgc tttatcaggt
    42481 ggtaaaggat cacattcata aaaagcaggc cttacaaaat cgtcagccca gctaattaac
    42541 agcatcagat caaggaaaac gtctatcaca agaccgattc cttggctttt ttattaccct
    42601 gtcatcattt tgtctgattt attgtgtatg gccttatttt tatgctgtag taaggaaaaa
    42661 agccgtctta tttatcgaat aatcattagt ggaggtaata agatgtattc catcaaaact
    42721 gatcataaat taatgcctag agagcgtttg attcgactgg ggccagaaaa gctaagcaat
    42781 caagagctat tagcgatcct acttaggacg ggcaacaagg aaaagcatgt cttagagctg
    42841 tctgcttatt tattgtcaag cttagatagt ctagctgacc tgaagaaatt ttccttacaa
    42901 gaactacagc gcttatctgg gataggaaag gtcaaggcta ttgaaattaa ggccatgctg
    42961 gagctggcag accgtattca gatagcggga caagcagtag cagatcctgt cttatctagt
    43021 gctcaggtgg ctgaaaagat gatgattgaa ttaggagaca agcagcagga gcatttagtc
    43081 gctatttatc tcgatagtca aaataaaatc attgaagaaa agacgatatt tataggaacc
    43141 gtcagaaaat caattgcaga gcctagagaa attctttatt atgcgtgtaa aaatatggcg
    43201 actagcctta ttgttgttca caatcatccc tcaggcctga ccaagccaag cgcaaatgac
    43261 tatcacttca cagaaaaaat aaaacgatca tgtgattatt taggacttat ctgcctagat
    43321 cacattatcg ttagtaagta tgactactat agctttcggg aaaaatcaga tttattttga
    43381 gttagaaact atggataaac caatcaaaga gccttaggtc ttcttctcta atagcctgaa
    43441 gcagctctgg gtgccactgg acaccgagaa agggaatatc aggattgcag gagataacag
    43501 cctcgatgat gccatcgtta ggatcccttg caatcactct taagtcctct gcgacctgct
    43561 ttaggctctg gtggtgaaat gaattaatca gcgctcttgg accatagata gggtacaaag
    43621 gtgaagtctt ttcgatcact atcccctgtg ataaacagtc agaggcagtc ttttgccaat
    43681 ggccctcaat gtgctggttt agactgccac ctagagcaac atttattaac tgcataccgc
    43741 gacaaatccc taaaattggt tttttctgcg ctagggcttc tttaatgatg gctagctcaa
    43801 aggtgtcacg ctggggtgaa aaatcaccat caagtgcagc tcttttttca tgataatatt
    43861 taggatcaac atgctgacca ccaataagaa tgattttatc aaccattgcg acataggatt
    43921 tggcagccgc ctcatcccca atcggaagaa gtaagggtag gccaccagat cttgtcacag
    43981 cctcgatgaa gcctgttgga gcataggagc aaggcaggtt atctagagcc ttggtccccc
    44041 tttggttagc agttatccca ataattgttt tagacacgac cttctccatt aatcaagatg
    44101 attttggttc ataaagtata gcaaggtttg caactcgctg gtcaaatcaa cagattggac
    44161 gatcacacct tttggaacct gtaagtgaag tggagcaaag cttaaaatac cgcgaatgcc
    44221 agcttcaatc agttgatctg caacctcttg agcatagatg cttgggactg ttagaatagc
    44281 cgtttcaatg cctgaattat ccaggtgctc cttaatggta gaaatgccat aaataggaat
    44341 atcatcaggc gttttggtgc cgaccatagg attatcatca gtgtcaaatc ccataacaat
    44401 ctgcattttg tttcgatcgt ggaagcggta gtgaagaagt gcacgaccaa tattgccgca
    44461 gccaactaaa atcacatgcg ttgttgagtg atcatttagc aaatctgcaa aaaaattcat
    44521 taattttgtg acatcatagc caaatccacg tcggcctaat tcaccaaagt aagaaaaatc
    44581 acgtcgaaca gttgcagaat caattcccat agcatcagca atctgttttg agcttgcctt
    44641 ttcaacctga tcagcataaa agcgtttaaa aatacgataa tagagtgata agcgttttgc
    44701 agtcgctttt ggaatagatt tatcaataac cacctttgta gctccttcta ttattatttt
    44761 aatgttatct atcaccattg tagcagatag attgtgaaat atgcaactat ttgaccattc
    44821 tttttgtgtt tttcgttata aaatgacttg acagcacaag cattggtatt tttcaaagcc
    44881 agtcacctcg agtataaaaa agcagacaat gaagcacttg ccctttaggt cagctgcgat
    44941 ggctgggctt gtcttgttaa aggcaaatgt actgtcattg tctgatattt ctctgagatt
    45001 agaagagctc ttgtgtgctt agcattcttt tttaatgaaa atatcacgct caacaaggct
    45061 atccattaaa aagtaaaact tgtcctgtag tatgctatgc tcttcagatt taaaaatgtt
    45121 caccagtctt agaccggatt ggtctgttat agctagctta aagccatcta aatctttatt
    45181 aatcgtaatt tttaaaggga agccctcacc cgaattaggg actttttcca gtagtcgtgt
    45241 taactgatag tgaccaatct tggtctgact aaaggttgtg tctcttaggg tgtatttttt
    45301 aatctttggg ctaatcctgt agctgtattt gcagtcttta agggcaattt ctttttcaaa
    45361 tgccatatga tcctcctaaa atatgtttga gctgggttgc tagtgcgata acgtcttttt
    45421 gagtattttg ctctgaaaag ctaattcgaa tagcttctgt gagacgatgg gactgcttgc
    45481 cgaaataagc tgccaaaacg tgacttggtt caacagcacc agctgtacaa gcagaacctg
    45541 atgatacagc aaagcctgct aaatcaagct gagtcagtaa gacatgattt tggtaactgg
    45601 gaaagccgat attgacgata taaggcaaat gatgatcgct atgattgagc tgataagaaa
    45661 tatctgccag ctcatcaagc aagagctgtg atagctcttt agcatgctgg taatgctgtg
    45721 gcagccttgc gatagcctca tctaatgctt gggtcatgcc gatgatatta atcaggtttt
    45781 cagtgccggc tcttcgtttg ttttcctgat tgccgccatg taagagaggg tctagcttta
    45841 agcctttatt gtataaaaaa ccagtcccct ttggtccatg aaatttatgg gcagaggcag
    45901 agagcaaatc aatccccaaa tctgctggct gtattggaac cttgccaata gcttggacag
    45961 cgtcgacatg aaagacagcc tgatgctgct taagcatgct gccaacagcc tgaataggca
    46021 gcaaatctcc agtctcgttg ttggcaaaca tcatgctgac taagattgta tcctctctta
    46081 gggcagcttt gagctggtct agatcaatga ttccgttttt aacctcaagg taggtcacct
    46141 caaagccaaa tcgttcttcc agataggcca ttgtgcttaa cacggaatga tgctcaatag
    46201 cagttgtaat caagtgtttg cctttttcct gatgagctag ggcatagccc ttgatagccg
    46261 tattgttact ttcagtacca cctgaggtaa agataatgtg gttttctgca gttcctaggc
    46321 agttggcaat agcttttcgg cactctctta attgtttgtt tgcctgccgc ccataagcat
    46381 gaatactaga tgggttacca aaatcatcag ccatagcttc agtcatcgcc ttgatagcag
    46441 cctgactgag cggtgttgta gcagcattat caaaataaat catgattagt tagtgctttc
    46501 aggtttgtaa gaaaacagtg gacttagtgg ttttctttcg tgaatgcgaa tgatagcctc
    46561 tgcaattaaa tcactggcac taaggtaggt tactgtttta gggatacgat ttttagtctt
    46621 gacagagtcc gtgacaatga tctctttgat tggagcagtc tctaaaatat cagctgcacc
    46681 tcctgcaaaa agcccatgac tagccactgc ataaatgtca gttgcgcctg cacgttctag
    46741 gatcttagct gcctctgcaa aggtttttcc tgtgttgaga atgtcatcaa tcaagatagc
    46801 cttcttgcca gcaacatcac caatcacata gccttcttcg cgctcagcat cgtcttgtgc
    46861 ataatcgata atggcaattg gagagttaag atattctgct aagcttctag cacgcttgat
    46921 accagaattt ttagggctga caataaccgt atcaggtcct gagaggccca gtggataata
    46981 gtgctttgca aaaagaggca ctgtaaataa attatcaact ggaatgtcaa aaaagccttg
    47041 gacctgaacc gcatgcaaat caagggttac aacgcgatca atccctgctt tggtcagcat
    47101 gtttgcgacc agctttgctg taataggctc gcgagacttt gcaacacgat cctgacgcga
    47161 ataaccaaaa tatggcaaaa caatattgac tgtattagca cttgcacgct tacaagcatc
    47221 aatcatgatg agcagctccc atagattatc gttgacagga aagcttgttg attgaatgat
    47281 ataaatatca tcaccacgaa ctgtttcttc aatgttaatc atgatctcac catcagaaaa
    47341 ttgacgagat gagacctttc caagcggaat accggcagcc ttagaaattt tttcagcgat
    47401 tgcgagattt gaagtgagtg agaacagctt gatttgctta tcagcatatc gttcagtcat
    47461 gataaaatta gctccttata ttacattaac gatagaataa caggtaatag attaacagtt
    47521 attcaagatt acaaatagac agtattattt taacaaaaaa acagaaaaat ttcagtcttt
    47581 ctgttgattt tctatgctct cctaggattt tcttagggtc ttactaaagc gagccacctt
    47641 gcttttggca tatttaaagg tgatctgatg ccgggctaaa aagtggtcaa aatcaacctt
    47701 tccttttaca ggatcagtca cctctagctc aagctcataa tctttgatac cagcgtattg
    47761 attataatcc agtgctagct tgccgatagg agtatctgct tctcgacgaa tggttgtcag
    47821 attcccaaag gtttttatgg cagataggtc aatgtcaaga gtactgataa tatcaaggat
    47881 agctgatttt ggcagctgtc ctgtctgaat gatagctttt gcttgggtgt catcaagctc
    47941 taaattgtac tcgcgattac caaccttttc agggactttt agggttaatt ccgcaggagc
    48001 agcaacaaag gtgcgaatgc gaagggacat tttatgagcc ttgagatcaa aatgatcagt
    48061 atcaatgtaa tagttcgtct gggtaactgg tgggacatga gtcatttgag agaggaggcg
    48121 attgtattcg tcctttgtca gcaaggtctt gtattcgatt tctaggttag tcatgcgaac
    48181 gttcctttta actatatttt gtgctataat aaattgttat cttaatttta tattaatatc
    48241 cgaggtttga caagaaagga gagaaaggat ggctttagat tgggaagaat ttttggatcc
    48301 ctatatacaa acggttggcg aattaaaaat taagctgcgc ggtatccgaa agcagtttcg
    48361 caagcaaaac cgttattctc ctatcgagtt tgtgactgga cgtgtcaagt cggttgagag
    48421 catcaaggaa aaaatggcct tgcgtggtgt cttggaagaa aatatcgctc aagatattca
    48481 agacatcgct gggcttagga ttatggtgca gtttgtggac gatattgagg acgttttgtc
    48541 cttgcttaga caaagacagg acatgacaat tgtttatgag cgagactaca ttagaaacat
    48601 gaaatctagt ggctatcgct cgtatcatgt tgtcattgag taccctgttg ataccattga
    48661 gggtcaaaaa aaagtattgg cagaaattca aatccgtact ttagcaatga atttttgggc
    48721 aaccattgag cattccttga actacaagta cggtggtgat tttccagaag aaataaaaaa
    48781 acgattagag gttacagcaa aaattgcttt ggagcttgat gaagagatgc gaaaaattcg
    48841 cgaagacatt cgtgaggcac aattgctgtt tgatcctgta acacgtcatt tgagtgatgg
    48901 tgtaggaaat agtgatgaca cagatgaatt atacagataa agtaaagcgc gttgctatta
    48961 ttgcaaacgg caaataccag agtaagcgac ttgcctcaaa gctttttggc gtctttaagg
    49021 acgatccggg tttttatcta tccaaaaaaa atccggatat tgtgatttca attggcggag
    49081 atggcatgct tctatcagcc tttcatatgt atgaaaaaga attagacagg gtgcggtttg
    49141 taggcattca cactggacac cttggctttt atactgatta tcgtgatttt gaggttgatc
    49201 aattgatagc caatcttaga agggacaccg gtgagcaaat ttcttaccct attttaaagg
    49261 tagttattac gcttgatgac ggtcgcctgt ttaaggctag ggctctaaat gaagcgacta
    49321 ttaagcgtat cgagaaaacg atggttgcag atattatcat taacaatgtc aagtttgaaa
    49381 gctttcgtgg tgatggcatc tctgtatcca caccaactgg aagcacagcc tataacaaat
    49441 ccttaggtgg agctgtattg cacccaacga ttgaagccct tcagctaaca gaaatctcga
    49501 gcctgaacaa tcgtgtattt agaaccttgg ggtcctcagt gattattcct aaaaaagata
    49561 aaattgagct tgttccaaaa agactaggcg tttatactgt ctctgttgac aataaaacct
    49621 accatttaaa aaatgtggtt aaggtggaat attttatcgg caatgaaaag attcattttg
    49681 tgtcttcacc tagccacacc agcttttggg aaagggttaa ggacgctttt attggggata
    49741 ttgaatcatg aggtttgaat ttgttgcaac taaaaaaaca aaggtcaaga cccttttaaa
    49801 ggagcacgat gtgtcaaagg ggctgctcgc taagattaaa tacaagggtg gcaatatatg
    49861 ggtaaatggc gttgcgcaaa atgccattta tttattggat attggtgatg tggtggctat
    49921 tgatattccc aatgaggagc cctttgagca attgacagct atttcgcatg accttgatat
    49981 tgtgtatgag gacgagcatt ttctcattct caacaagcct gctggctacg ctagtattcc
    50041 aagtgctatc cattctaata ccatagctaa ttttatcaag gcttattata tcgagcagga
    50101 ctatcccaat aaacaggtcc atattgtgac gcgcttagat cgggatacca gtggcttgat
    50161 gctctttgcc aagcatggct atgctcatgc cagattagat aagcagctac agcaaagggc
    50221 tatcaataag cgctattatg ctcttgtgtg tggtcaggag aggcttccag atcaaggcga
    50281 gattatagct cctattggac gtacggacga cagcattatc acaagaactg tcacgccaaa
    50341 gggaaagtat gctaagacaa gctacaaggt cattgcccgt taccctgaaa atgtctctct
    50401 agtggatatt aggctgcaca ctggtcggac ccatcaaatt agggtacatt ttgctcatct
    50461 tggttttcca cttttgggag atgatctgta tggtggtcga ttggaccttg gcatgactag
    50521 acaggcgctg cattgtcacc atcttagctt tacgcaccca tttacagaaa gtagaagcga
    50581 tcatacaata tgcttgacag atgactttga gagcgttatc atagatttac agaaaaaaag
    50641 atagaggttg attaatgagt attcgtaatt tatttggtgg tttaagggaa aaaattgtcg
    50701 gtaaaaacat gaagattgtt tttcctgagg gaaatgatga gcgtgttgta cgtgcggcag
    50761 cacgtctaaa gtttgaagga cttgttgagc caattatcct tggtcaggca gatgatattc
    50821 gcagtcttct aacacaacta ggctttgctg atcagcatta caccatcatc aatccaaatg
    50881 attatgctga ttttgagaag atgaaagcag cttttgtaga gcttcgtaag ggcaaggcaa
    50941 cgcttgaaga tgctgataga ttgcttagag atgttaacta ttttggtgtg atgttagtta
    51001 agctgggctt agcagacggt atggtttcag gggctattca ttcaacagct gatacggtgc
    51061 gtccggcgct tcagatcatc aagacaaagc cgggcatttc tagaacatca ggtgtctttt
    51121 tgatgaatcg cgaaaataca gagcagcgtt tagtgtttgc tgattgtgcc attaatattg
    51181 acccaacggc tcaggagctc gcagaaattg cggtaaacac agcagatact gcgaaaattt
    51241 ttgatattga tcctaaggtt gccatgctta gcttttcaac aatgggctct gctaaagccc
    51301 cacaggttga aaaggttcaa gaggccgtcc gtattgctaa ggaattgagg ccagagcttg
    51361 ctttagacgg tgagcttcaa tttgacgcag cctttgtacc aagtacagca gcgatcaaag
    51421 cccctgattc atcagtggca ggccatgcga atgtttttgt cttcccagat ttacagtctg
    51481 gaaatattgg ctataagatt gctcagcgct taggcatgtt tgatgctatc ggaccaatcc
    51541 tgcaaggatt gaacaagcct gttaatgatt tatcacgtgg ctctagtgca gaggatattt
    51601 acaaactagc tattattaca gctgcgcaag cacttgaaaa tgagcctatc aattaactgc
    51661 taatagctgt tgagctcata atgcttggct atagtagatg ttgcttaaaa cgagttggat
    51721 aagccagctc gttttttcag aaagtgagga aggaaatgac aaagattgca ttagtaacag
    51781 gtgcctctgc tggctttggt aaagccattg ccgagcagtt aatagcccaa aacatcaagg
    51841 tgatcggagc agcccgtcgc atagaaaagc taagagagct agaaggtatt tttggttctg
    51901 agaggtttta cccgcttcaa atggacgtct caaagcccgc tgctattgat agagcacttg
    51961 cagcattacc taaagaatgg caggccattg atattttagt caataatgca ggactagcct
    52021 taggacttga caaggcctat gaggctgatg tagccaactg gctaaccatg gttaacacca
    52081 atatcatcgg gcttatctat ttaacacgtc aggtattacc gcagatggta agcaccaaca
    52141 atggcatgat catcaatatc ggctcaactg ctgggactat tccctatccg ggagctaatg
    52201 tttatggggc ttcaaaagcc tttgttaagc agttttcgct taatttaagg gcagatttag
    52261 taggaacaaa gatcagggtg accaatattg agcctggcct ttgtgaggga acagagttct
    52321 ctcatgttcg ctttaatggt gaccaagcgc gtgttgaagc actttatgca ggtgcacatg
    52381 ctatccagcc aagagatatc gcaaacaccg tctcatggat tattaatcag ccagagcatg
    52441 ttaacattaa tcgcgtggaa atgatgcctg tctcacaaag ctacggccct cagcctgtta
    52501 gtcgtcatga ctaagaactg caagtgcagc tgtaaaagga ttgtcgaagt gcagcccaaa
    52561 aagacttaaa gccaagctcc ttcatagcct gactttaagt cttttttcta gcttttctta
    52621 gaaatgatct gaaagagaag gtccagatgt gacatctgac cacccaacaa tggcctgccc
    52681 tgtttcttct aaatagtgct gaagcatagg cttgaagtcc aaaatcgtgt catagacccc
    52741 gacaaattgc ttgctatcat cgtacaaggc ctgatattgc tgcatataaa tatggtcctg
    52801 tgaagcagtc ggaataagat acagcttact gccagttgcc gccttgtgta aatcagtcaa
    52861 gatccaatcc tcaatgacat catgctcatc agaagcaaaa aagctgccat tgaagcgctg
    52921 attatcaaag acaatctgcc cctgatgatc agcaattcta gcctgaaatg gaagataggt
    52981 taaaaaatgt ggggttaagg cttggtaaaa ttgcgtgagg tatttagcga gccctaaagc
    53041 ctgctgcccg tcagtaaagg tatgatcact aacggtaaag ccttgctctt tgtctgcctg
    53101 attaaaataa agcacaggca gcgaggcttc aagatcctga aaggtgaaaa tagcctgagc
    53161 ctttttgagc tgctcagcag tcagctgacg gacaatggtg atatgaaaca gatagctaaa
    53221 cctttgtgat aaggtggtaa aaaaagtatt ttgcagacta tttttatcat caactaaagc
    53281 cagagtataa atcattttag tcataaggct atcatagctt tattttgctt aaatagcaat
    53341 ga
//
LOCUS       DARYSY010000008        52695 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYSY010000008 DARYSY010000000
VERSION     DARYSY010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52695
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..256
                     /locus_tag="TVR04_000379"
     CDS             <1..256
                     /locus_tag="TVR04_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269095.1"
                     /translation="SLHYVLFDEEKRLPWAFHLYQKNGKFYVEGRDERSYIIGHSREY
                     RKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPSPLWNE"
     gene            533..1143
                     /locus_tag="TVR04_000380"
                     /pseudo
     CDS             533..1143
                     /locus_tag="TVR04_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1125..1547
                     /locus_tag="TVR04_000381"
     CDS             1125..1547
                     /locus_tag="TVR04_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269096.1"
                     /translation="MARSKLEWEDVSQYEEIKGYGQQVWKHQGTYYLVTNEGGIAEQR
                     VVYELPRELFQLLEQGKQNLGEIAFKLRYDCWPPTEEEKNRIMKERAKDRPMVLISNP
                     KNQMLFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            2077..2787
                     /locus_tag="TVR04_000382"
     CDS             2077..2787
                     /locus_tag="TVR04_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1269097.1"
                     /translation="MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQSPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRAIRKKYPDQLFMADISTLEEGLAAYEAGVDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEE"
     gene            2792..4303
                     /locus_tag="TVR04_000383"
     CDS             2792..4303
                     /locus_tag="TVR04_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1269098.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTSAQGSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4305..4820
                     /locus_tag="TVR04_000384"
     CDS             4305..4820
                     /locus_tag="TVR04_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1269099.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAVMPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLVHIGVDTVELGETAF
                     SSDIVAGQEVVAGQLLAQVDLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAAKA
                     EVGQVRLKATL"
     gene            5223..5357
                     /gene="rpmH"
                     /locus_tag="TVR04_000385"
     CDS             5223..5357
                     /gene="rpmH"
                     /locus_tag="TVR04_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1269100.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            5645..6370
                     /locus_tag="TVR04_000386"
     CDS             5645..6370
                     /locus_tag="TVR04_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1269101.1"
                     /translation="MLEKPSKVELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQSPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALTSSLSIKNN"
     gene            6389..7702
                     /locus_tag="TVR04_000387"
     CDS             6389..7702
                     /locus_tag="TVR04_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1269102.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGSLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            7803..8690
                     /locus_tag="TVR04_000388"
     CDS             7803..8690
                     /locus_tag="TVR04_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1269103.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LIALISFAQFKFLGNDVEY"
     gene            8703..9533
                     /locus_tag="TVR04_000389"
     CDS             8703..9533
                     /locus_tag="TVR04_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1269104.1"
                     /translation="MKKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTIENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            9560..10015
                     /locus_tag="TVR04_000390"
     CDS             9560..10015
                     /locus_tag="TVR04_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1269105.1"
                     /translation="MLYDVLENIRRYKGIHHHLDLAIDFLMTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALLEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDGGDAVTKCLIKVLMED"
     gene            10040..10690
                     /locus_tag="TVR04_000391"
     CDS             10040..10690
                     /locus_tag="TVR04_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1269106.1"
                     /translation="MSSKKRKLVQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKIALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLH"
     gene            10719..11639
                     /locus_tag="TVR04_000392"
     CDS             10719..11639
                     /locus_tag="TVR04_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1269107.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLPELTEADLVICQQAAALIKQTKEQFCY"
     gene            11654..12538
                     /locus_tag="TVR04_000393"
     CDS             11654..12538
                     /locus_tag="TVR04_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1269108.1"
                     /translation="MKHYLAIDIGGTAIKYGLMTETGDLLEKHEMATEAHKGGPAILD
                     KVKDLVAAYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CEVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDPVSAWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQIRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            12538..13506
                     /locus_tag="TVR04_000394"
     CDS             12538..13506
                     /locus_tag="TVR04_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1269109.1"
                     /translation="MIETMSLEEMMSYRGRHEVPKDFDHFWETCIKENQAASYQLDQK
                     DFGLDFADCYELRFKGSNGSTIYAKCVFPKAKQLVPVVFYFHGYQGQSPDWSDQFNYL
                     AAGYAVVSMDVRGQAGYSQDLGQFDGITVKGQVIRGMTSGPEQLFYKDVYLDVYQLID
                     IVSAFARVDDSRLYSYGWSQGGALSLIAAALHPKIAKTVAVYPFLSDFKRVLELGNHS
                     EPYDELFRYFKYHDPFHDTEAEVLGNLAYIDVKNFAHLITCPVVMLTCMEDVICPPST
                     QFAIFNRLATADKCHKLIPDYGHDPMGVKVKDFIFDQLTGSHFTKA"
     gene            complement(13654..14478)
                     /locus_tag="TVR04_000395"
     CDS             complement(13654..14478)
                     /locus_tag="TVR04_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1269110.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFVFECQKSREAMDQKAPNLQNSNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            14707..15480
                     /locus_tag="TVR04_000396"
     CDS             14707..15480
                     /locus_tag="TVR04_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1269111.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDRLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRIG"
     gene            15452..16048
                     /gene="rnmV"
                     /locus_tag="TVR04_000397"
     CDS             15452..16048
                     /gene="rnmV"
                     /locus_tag="TVR04_000397"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1269112.1"
                     /translation="MQRGCLGLAEKLKIHEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYNGERIRKLIMGAVPTARHAFLHRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMSSYQTEQ"
     gene            16388..17260
                     /gene="rsmA"
                     /locus_tag="TVR04_000398"
     CDS             16388..17260
                     /gene="rsmA"
                     /locus_tag="TVR04_000398"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1269113.1"
                     /translation="MRIADYSVTKAILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSHPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKSSIRGEALSIQ
                     DFGRLADALKQVGL"
     gene            17421..18293
                     /gene="rsgA"
                     /locus_tag="TVR04_000399"
     CDS             17421..18293
                     /gene="rsgA"
                     /locus_tag="TVR04_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1269114.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNANLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIVPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRHLSHSCKFRSCTHTHEPKCAVKEALENGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            18302..18964
                     /locus_tag="TVR04_000400"
     CDS             18302..18964
                     /locus_tag="TVR04_000400"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1269115.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTNAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMRAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            18957..19589
                     /locus_tag="TVR04_000401"
     CDS             18957..19589
                     /locus_tag="TVR04_000401"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1269116.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIRVHVPKGYLVIIQSKDRS"
     gene            19591..20862
                     /locus_tag="TVR04_000402"
     CDS             19591..20862
                     /locus_tag="TVR04_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1269117.1"
                     /translation="MDLILLVLVLALIGLAAYSFVSIKHLQSRLEKALDNNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMDIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNRVLSNTKTRGILGELQLGQIIEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRTAIETSRKALLAAIKRFAKSIH
                     SKYLSPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEDYQDQSTQSLLHIPLLEEADDED"
     gene            20852..21790
                     /locus_tag="TVR04_000403"
     CDS             20852..21790
                     /locus_tag="TVR04_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1269118.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMRGRREVYNGTPQVNQITLRNVRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRVGEGEMTNRIFAMDNRSFYKPKY"
     gene            21890..22705
                     /gene="purR"
                     /locus_tag="TVR04_000404"
     CDS             21890..22705
                     /gene="purR"
                     /locus_tag="TVR04_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1269119.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            22742..25246
                     /locus_tag="TVR04_000405"
     CDS             22742..25246
                     /locus_tag="TVR04_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1269120.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSYQVKADDTSSGNT
                     NTSNANEGNLAKPETLEEAVLAVKATEETLSEQKKELAEVDTQATKAEAEIAALEATK
                     KEQAADLAKAEEILETYSSMSEEDLAKSIEKHEAELETVSSELEQVTADGQAQAEAVA
                     KQQEAIVTETATANQLSEQLAAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKDTVHSQLTSDLAANKAALAAKEAELQRLQDGTATAQLNVAGSNKLVL
                     PEGYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLPEDIQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKATHQNTR
                     PSFVYGQVDASGHRGVGPHDETIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTNPNAPVYLGFSTSNVGSLNEHFVIFP
                     ASDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRAKLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPISHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLATAGLATVKLKKGSKKR"
     gene            25429..25842
                     /gene="rpsL"
                     /locus_tag="TVR04_000406"
     CDS             25429..25842
                     /gene="rpsL"
                     /locus_tag="TVR04_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1269121.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            25863..26333
                     /gene="rpsG"
                     /locus_tag="TVR04_000407"
     CDS             25863..26333
                     /gene="rpsG"
                     /locus_tag="TVR04_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1269122.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            26661..28739
                     /gene="fusA"
                     /locus_tag="TVR04_000408"
     CDS             26661..28739
                     /gene="fusA"
                     /locus_tag="TVR04_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1269123.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            29119..30129
                     /gene="gap"
                     /locus_tag="TVR04_000409"
     CDS             29119..30129
                     /gene="gap"
                     /locus_tag="TVR04_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1269124.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDQFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKEVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            30685..31539
                     /locus_tag="TVR04_000410"
     CDS             30685..31539
                     /locus_tag="TVR04_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1269125.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            31749..32945
                     /locus_tag="TVR04_000411"
     CDS             31749..32945
                     /locus_tag="TVR04_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1269126.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLILPVDSKEANAF
                     ADYTEVKVTEGEAVDAGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            33368..33889
                     /locus_tag="TVR04_000412"
     CDS             33368..33889
                     /locus_tag="TVR04_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1269127.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQSAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            33965..34336
                     /locus_tag="TVR04_000413"
     CDS             33965..34336
                     /locus_tag="TVR04_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1269128.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLNEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            34373..35719
                     /locus_tag="TVR04_000414"
     CDS             34373..35719
                     /locus_tag="TVR04_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEL1269129.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKEGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            35952..37610
                     /locus_tag="TVR04_000415"
     CDS             35952..37610
                     /locus_tag="TVR04_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1269130.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRVDAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKGWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQLYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPEGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKATEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKE"
     gene            37777..38691
                     /locus_tag="TVR04_000416"
     CDS             37777..38691
                     /locus_tag="TVR04_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269131.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNNPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLVVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILVTDMIISIADPRVRLG"
     gene            38701..39732
                     /locus_tag="TVR04_000417"
     CDS             38701..39732
                     /locus_tag="TVR04_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269132.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYVDQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASLGSLITDAQENLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            39745..40791
                     /locus_tag="TVR04_000418"
     CDS             39745..40791
                     /locus_tag="TVR04_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269133.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRNISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGDICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMADRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            40791..41726
                     /locus_tag="TVR04_000419"
     CDS             40791..41726
                     /locus_tag="TVR04_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1269134.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQDHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERRRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEADQYRAERDL"
     gene            complement(42278..43960)
                     /locus_tag="TVR04_000420"
     CDS             complement(42278..43960)
                     /locus_tag="TVR04_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1269135.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(43962..44192)
                     /locus_tag="TVR04_000421"
     CDS             complement(43962..44192)
                     /locus_tag="TVR04_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1269136.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EYTDYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            44478..45176
                     /gene="tsaB"
                     /locus_tag="TVR04_000422"
     CDS             44478..45176
                     /gene="tsaB"
                     /locus_tag="TVR04_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1269137.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLADLVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            45179..45604
                     /gene="rimI"
                     /locus_tag="TVR04_000423"
     CDS             45179..45604
                     /gene="rimI"
                     /locus_tag="TVR04_000423"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1269138.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNR
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            45594..46610
                     /gene="tsaD"
                     /locus_tag="TVR04_000424"
     CDS             45594..46610
                     /gene="tsaD"
                     /locus_tag="TVR04_000424"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1269139.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAKEIKDLDVVMPPLRLCGDNAGMIALAAAVEYDKGHVAGLDLNAKPSLAFES
                     FHQQ"
     gene            46632..47660
                     /locus_tag="TVR04_000425"
     CDS             46632..47660
                     /locus_tag="TVR04_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1269140.1"
                     /translation="MFYLLLLPLICSVVFLAVYVKEPRTLWLGASFVATLGVSLLCAM
                     IYIFSIENRLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSLRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSAYTISSILNT
                     FYLRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQVYRKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILFSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRGYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            47817..48038
                     /locus_tag="TVR04_000426"
     CDS             47817..48038
                     /locus_tag="TVR04_000426"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269141.1"
                     /translation="MEPITIVTAKSRPLGTFALLVSPFTCRGWLHQPKAKASDLACDD
                     QGVLRRKKIARYLGIPSYHDKLASMITKS"
     gene            complement(48055..48324)
                     /gene="rpsN"
                     /locus_tag="TVR04_000427"
     CDS             complement(48055..48324)
                     /gene="rpsN"
                     /locus_tag="TVR04_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1269142.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(48521..49690)
                     /locus_tag="TVR04_000428"
     CDS             complement(48521..49690)
                     /locus_tag="TVR04_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1269143.1"
                     /translation="MIAYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNRRLGKKLAG
                     TGGGRCNVTNSGSLDELIAGIPGNGRFLYSVFSQFDNYDIIAFFRENGVPLKEEDHGR
                     MFPATDQSKTIINALEQKIKSLGAQVLTSTEIVSVKKRDNLFYLKSADQTFSCEKLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKALMPERVADFLTKGYPEKGKQLTPTQTQELVNKIKQLPIPITGKMSLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDINAHTGGFNITAALCSGWVAGSPH"
     gene            49816..50346
                     /locus_tag="TVR04_000429"
     CDS             49816..50346
                     /locus_tag="TVR04_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1269144.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            50391..50978
                     /locus_tag="TVR04_000430"
     CDS             50391..50978
                     /locus_tag="TVR04_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1269145.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAITDNPFAALGGLFD"
     gene            51082..51804
                     /locus_tag="TVR04_000431"
     CDS             51082..51804
                     /locus_tag="TVR04_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1269146.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDNRNLLSPSAITDGGRRQYT
                     SADLSQLKRILFLRELDFSIERIKRIFAEDNTDQVLELLLQEHIRQLRAEAADKKAKL
                     DRAVKLLKEVEKDACQSLDDLSDLALRIENQESWRQLQRRTWPQLILAIISYVLVMVL
                     AAWLRQIWLIWLGMSLFILAVNGLVWHYKKQVPYLCPNCHKIFEPTYKVFSLAGHTPK
                     TRRLRCPHCQQKSYCLELAKEK"
     gene            complement(51846..52145)
                     /locus_tag="TVR04_000432"
     CDS             complement(51846..52145)
                     /locus_tag="TVR04_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1269147.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAATSFSGKSAQELVTATFT
                     GDKRLVNITFKEAVVDPEDIETLQDMTTQAINDALTQIDEATKKSLGAFAGKLPF"
BASE COUNT        14785 a        10216 c        12517 g        15177 t
ORIGIN      
        1 gagtttacat tatgttttat ttgatgaaga aaagcgactt ccttgggcat ttcatcttta
       61 tcaaaaaaat ggaaaattct atgttgaagg aagagatgag cgatcatata tcattggtca
      121 tagcagggaa tatcgtaaat ttgatgatgc caagcatgaa ttgcttaaaa aattagaatt
      181 agttatagaa tctaatcggt taaaaaagca gttaggtgaa cctacagaat atccctcacc
      241 actatggaat gaatgagttt catgtattgt atgtcatggc accaagcttt taggaggcag
      301 ctagcaagac gcccagcgag ctaccttggt agggaatacc ctaggaggct atgccgcctc
      361 aagcgccgcc agaaggttca gcttgaatga gccgatagca gctagggtga cgaaaccagc
      421 ctacaaccgc cagcagcttt tgaagaacct tgaaagcagc agactggcaa gagaaagctc
      481 aaggtttaag aattatgtag caagagaaaa attcacgaca acccttgcag gcatgagtcc
      541 tgaggatagt cagcgctata ttcaatggca caaatacgca aaggctggac ttagtccgtc
      601 agatcgagta aggattctag aaatatctga gaaggcaccg aagatagagt atcttccagg
      661 taagaattct aaaactattc tagcacaggc aaaaggaaaa cgagatagtg ttgaactgta
      721 cctcgcttca gaatatattg aaacccatcg tcatttgttt gataatggag ttgctagatt
      781 ccaaaggttc caactagtga aagttggaac aatggggttg ttggtggtaa ggatggcatg
      841 agcttctggg ttagtaagga tcatgcggat gttattgagg atattgccaa gggtgataat
      901 cgtctctacg agacgctact tggtttcgat gaagggtatt tgggagatgg ccctctttac
      961 cgattagatg tttcaccaga ggttatttca gagaaaggta tttctattcc aagtggtaat
     1021 gaaaagagtg ctaatagctg gtggcgacct ggaggtcgta cctatccagg tgatatgcca
     1081 gagggagtta tgaaagatat cagtacaagt aaaggagatc acacatggca cgtagtaaat
     1141 tagagtggga agatgttagt caatatgagg aaatcaaggg ttatggccaa caagtgtgga
     1201 agcatcaggg gacttactat ctagtgacta atgaaggcgg tatagctgag cagcgagtag
     1261 tatatgagtt gcctagagag ctgttccaat tattggaaca aggaaaacag aacctagggg
     1321 agattgcttt taaattgcga tatgattgct ggccaccaac ggaagaagag aaaaatcgca
     1381 taatgaaaga aagagccaaa gatagaccaa tggtcctcat ttctaatcct aaaaatcaaa
     1441 tgctttttac ccaagaagag ctaagaaaac tgattccaat tgcggagcaa aaatggatag
     1501 attggaaggg aaagttacca gatgattatg tcagtccttt gaaataatgt ttaagatagc
     1561 ggatctgagg gcagctatgt tagaggcccg ttgttagctg tattaggtag gtgaaaagtg
     1621 gttagttttg ggtacaatca aaagttctat atataaccct tgcggtggag ttacccacta
     1681 cgggtattgt agagcctgaa aagttgggtg cgagagagga ctggactggt tctctctttt
     1741 ttgtctcttt gtcaagctta tcaagcaata ataggaccta aggtagttct tgttgagaca
     1801 tattgccgta tttggcctta actggctggc aaaaaggctt ttatggtaag aaggtatgtc
     1861 ttgtaaggtt ttgctgttgt tgtatcaatt agtaaatagc tcaataggct agctctttgc
     1921 catacttaag gctattgaat atgctttcag aaaacaagga tttttctctg aaaatgaaag
     1981 tacttcctaa aagtgggctg tctattgaaa gtgttttaat atctgctaca ataaagatgt
     2041 gaacgttctc taaaattaat aaaaggagta gaaagcatgc ttgaaaaacc aagcaaggca
     2101 gagctactgg cagctctgaa agacgggctg atcgtttcct gtcaagccct gccgggcgag
     2161 cctctctatt cagaggcagg aggtatcatg cctctgatgg caaaggcagc agaggaagca
     2221 ggggcagtag ggatacgagc caatggtgtt cgagatatta aggaaatcca agcggtgacg
     2281 gatctgccaa tcatagggat cattaaaaag gagtatcccc ctcaatctcc ctttatcacg
     2341 ccaaccatgg cagaggtaga cgccttagcg gccttagatg tagcggtgat agccttggat
     2401 tgtacgcaaa gggagcgtca tgatggctta gcgatagcgg actttattcg agcgataagg
     2461 aagaagtacc cagatcaatt gtttatggca gacatcagca cgcttgagga gggtctagca
     2521 gcctatgagg ctggtgtaga ttttgtaggg acgaccttat cagggtatac gccttatagt
     2581 cgtcagggga caggtccgga tatggagctg ataagtgcct tgtgtgatgc aggggtatca
     2641 gtgatagctg agggcaagat tcatagtcca gaggaggcca gggctgttca ggccttggga
     2701 gtagctggta ttgtggttgg tggtgctatt accagaccaa aggaaattgc agagcgcttt
     2761 gtagcggctc tcaagaagga ggagtaatca catggatttt aagaaatttt caaaattggg
     2821 tcaagccttt atgctgccga tctcaatctt accagtagct ggtttgttgt tggggattgg
     2881 tggggcccta tcaaatagca atgccattgc acaatttccg atattaaatc aagcatggct
     2941 acaggctatt tttaccatta tgagcacagc aggtaacgct gtttttgcta atattgcctt
     3001 gatttttgcg attggtgttg ctgttggctt agccaacgga gataaaggaa cagccggtct
     3061 ttcaggtgct gtggcttatt tggtctttac ggcaaccatt agcggctatc tgactctttt
     3121 ttcagcaaag gacgctcaga ttgatacggg tgttttaggg gctttgacgg ttggtttagt
     3181 tgttgtgagc cttcacaata agtaccgaaa gatcgaactg ccagcctttt taggcttctt
     3241 tggcggctct cgttttattc cgattgtttc ctcattggca gcgattgtga ttggtagtgt
     3301 tttctatgtc atttggccac ctattcaaaa tctcctagta gtgtttggtg aaaaaattgc
     3361 ggatatgggg agcatcggaa cattcttgta cggtttcttt ttacgtctga caggagcagt
     3421 agggctacac cacaccattt acccaatgtt ttggtataca tcacttggcg gcagtgaggt
     3481 tgtagcaggt gagactatcc aaggagcaca aaatatcttc tttgcgcaat tggctgatgc
     3541 taatcatact ggcttgttta cttacgggac acgctttttt gcaggacgtt ttgcaaccat
     3601 gatgtttgga ctacctgctg cctgtcttgc tatgtatcac gctattccaa aggctaatcg
     3661 taaaaaggtt ggtagctttt attcaagtag tgccttgact tcattactaa cagggatcac
     3721 agagcctatt gagtttgcct ttttattcgt agcaccttgg ctctatgtgg ttcacgcttt
     3781 cttagatggc tgttccttct tagttgctga tttattaaag attcgtatcg gtaattcctt
     3841 ctcaggtggt ttgatagact ttttaatctt tggtgtgttc caaggaaatg atcataccaa
     3901 ctggctactt gttatccctg ttggtatcgt gtggtttatg gtttattact ttgtctttaa
     3961 attctttgtg agcaaattcc aggttgctgt accgggaatg gtagctcagg tagaagcaga
     4021 aggacaagca gagactacta gtgctcaagg ctcatcactt cgtgaggtgt cattagctat
     4081 tattgaggct ttgggtggac aagctaacat cgaagatgta accgcttgcg cgactcgctt
     4141 gagagtgtct ctgtcagata gtagcttggt caacaagaat gtcttaacct cactgggagc
     4201 aacagctgta ttagatgtta aaaatggcat tcaggctatt tatggtggta aggctatctt
     4261 gtatagtcaa gaaatcaatc aactattagg tagagaagat taacatgata aagaagtgga
     4321 agcaattatt atcagcaaaa aaagctgatg cgttaagcga tcgtatttta tcagtggcta
     4381 agggacaatt agttcctatt accagtgtca gtgatcctgt cttttcagaa aggctaatgg
     4441 gcgatggttt tgctgtgatg cctcaagagg gtgctattta cgctcctgtg acaggaaggg
     4501 taatgacggt ttttccgacc aagcatgctt atggcatcgt tactccagct ggtcttgagg
     4561 tattggtgca tatcggtgtt gatactgttg aattaggaga gactgccttt agctctgata
     4621 ttgttgctgg tcaagaggta gtcgctgggc agctattggc tcaggttgac ttaccagtgc
     4681 ttgaggccgc tcaaaaggat agcactgtga tggttgtctt tacaaactca caggacattg
     4741 ctgatatgcg tcttgctgat gctggagcag ttgctgctaa ggcagaagtc ggccaagtta
     4801 ggctaaaggc tactctctag ctagaggcta tcgatccagt ccttgatgac aactaaaagg
     4861 tcatatgaaa aaactgcacc ccagcacttg gctaagccgg tcaatgcctt ggggtgcttt
     4921 tattattgtc agcaatcagc aggctttgat tgtcctatct tttaacctct atttaaatgt
     4981 taacagctgt cgtatgtgcc ttgtggcaaa taaaagaaaa gctcagcgac ctgtttttca
     5041 tattgcttcg cacattttat tttagggggc tattatatcc tccccagtat acaagggctg
     5101 aaaaaggaaa atagagcttg acaggggagt ttgattatta tagaatagta gggtatgttt
     5161 agtaactgat atcacaaata gccggctaaa cgaatacgaa aatctatgag gaggtattca
     5221 ctgtgaaacg tacttatcaa ccaagtaaga tccgtcgtca gcgcaagcat ggcttccgtc
     5281 accgtatgtc aactaaaaac ggccgtcgtg tgcttgctag ccgtcgtcgc aaaggacgca
     5341 aagtattatc agcataattg cagaatacat caattaaaca aatcaggagt gctcgaggct
     5401 cttggttttt ttaattgttc aaaagtgcta agagcagctt gatgagtgct tataaagcag
     5461 gagataggag ccaaaaagag gctgcttttt taattgctct tcctgaatac gttttcaaaa
     5521 atagcggaaa taagtctaaa aatgaaagta gtttctaaaa ccagaggagg tattgaaaac
     5581 gctttaatat ctgctacaat aaagatgtga acgttctcta aaattaataa aaggagtaga
     5641 aagcatgctt gaaaaaccaa gcaaggtaga gctactggca gctctgaagg acgggctgat
     5701 tgtttcctgt caagctctgc cgggcgagcc tctctattca gaggcaggag gtatcatgcc
     5761 tctgatggca aaggcagcag aggaagcagg agcagtaggg atacgagcca atggtgttcg
     5821 agatattaag gaaatccaag cggtgacgga tctgccaatc atagggatca tcaaaaagga
     5881 gtatccccct caatctccct ttatcacgcc aaccatggca gaggtagacg ccttagcggc
     5941 cttagatgta gcggtgatag ccttggattg tacgcaaagg gagcgtcatg atggcttagc
     6001 gatagcggac tttattcgag cgataaggaa gaagtaccca gagcagctgt ttatggcaga
     6061 catcagtacg cttgaagagg gtctagcagc ctatgaggct ggtatagatt ttgtagggac
     6121 gaccttatca gggtatacgc cttatagtcg tcaagggaca ggtccggata tggagctgat
     6181 aagtgccttg tgtgatgcag gggtatcagt gatagctgag ggcaagattc atagtccaga
     6241 ggaggctagg gctgttcagg ccttgggagt agctggtatt gtggttggtg gtgctattac
     6301 cagaccaaag gaaattgcag agcgctttgt agcggctttg acatcgtcat tgtctataaa
     6361 aaataattaa tataaaggag aatttacaat gaaaatgaag aaattagctt catttgtgat
     6421 gcttggagca tctgttttag ggttagcagc ctgtggcagt agcagcaagg aggctgacaa
     6481 atcagattca gctgctaaga cagagatcac ctggtgggcc tttccaacct tcactcaaga
     6541 aaaggctgat gatagcgtag gaacctacga aaagaaaatt attgcagcct ttgaaaaggc
     6601 caatccagat attaaggtca agctagaaac cattgatttc acctctggtc cagaaaaaat
     6661 cactactgcg attgaggcgg gtacagcacc ggatgtgctt tttgacgctc cgggtcgtat
     6721 cattgagtat ggtaaaaacg gtaaattggc tgacttaaat gacctgttta ctgatgagtt
     6781 tatcaaggac gtcaacaacg ataacattat ccaagcctct aaagcaggag atacagctta
     6841 tatgtatcct atcagctcag cgccgtttta tatggcctta aataaaaaaa tgctcaagga
     6901 cgctggtgtt cttgaccttg tcaaagaggg ctggacaacc gatgattttg aaaaggtctt
     6961 aaaagccttg aaggataagg gatacaatcc tggttcattc tttgccaatg gtcagggtgg
     7021 tgaccaaggt cctcgtgcct tctttgccaa cctctatagc agccgcatca caaatgacga
     7081 tgtgactaag tacaccactg atgatgctaa ttctgtcaag agcatggaga aaatcgcaag
     7141 ctggattaag gatggtcttc taatgaatgg ctctcaatat gatggctcag ctgatattca
     7201 aaactttgct aatggtcaaa cctcatttac aatcctatgg tcaccagcgc aagcaggaac
     7261 acaggctaaa ttgttggagg caagtaaggt tgattatgtt gaggttccat tcccatcaga
     7321 ggacggcaag cctgaattag aatacctagt gaacggcttt gcagtgttca acaacaagga
     7381 cgacaaaaag attgaagctt ctaagaaatt tatccagttt atcgcagatg ataaagaatg
     7441 gggacctaaa aatgttgtcc gtacaggcgc tttccctgta agaagctctt atggcagcct
     7501 ttatgatgat gaacgtatgg caatggtttc taagtggaca caatactatt caccatacta
     7561 caacactatt gatggctttg ctgagatgag aacactatgg ttcccaatgg ttcaggcagt
     7621 atcaaatgga gatgaaaagc ctgcagcagc cctaaaagca ttcactgaaa aagcaaataa
     7681 aaccatcgaa aaagcacaat agtgtgagat aaaagtggct ccttttcaat gcacatgtcc
     7741 aatggtcact ggtaaggagc ctttcctttt aggaagatta atagaaaaag aggtatcttt
     7801 gagtgaacgt caataagtta aaaatgagag agacactcgt ttcatatgct tttttggccc
     7861 cggtcttggt tttctttgtg gtatttgttt tagtaccaat gattatgggc tttgttacta
     7921 gcttttttaa ttatacgatg acagacttta cctttgtcgg gcttgataac tatgtgagaa
     7981 tgtttcagga tcctgtgttt ataaagtctt tgattaatac ccttattatt gtagttggtt
     8041 cagtaccaat tgttgttttc ttttcattat ttgtagcgac aaaaacctac aataagcatg
     8101 tgatttcgcg ttctttttat cgggcggttt tcttcctgcc tgttgtaaca ggtagtgttg
     8161 cggtaacagt tgtttggaaa tggatctatg atcctatgtc aggtattttg aactatgtgc
     8221 taaagtatgg gcatgttatt gagcaaaata ttagctggct tggggacaag cattgggctt
     8281 tgctggctat tattgtgatt ttattaacaa cctctgttgg gcagccgatt atcctataca
     8341 ttgctgcaat gggaaatatt gacaattcct tggtagaggc ggctcgtgtt gacggtgcga
     8401 ctgagttgca ggtcttttgg aagattaagt ggccgagttt attgccaacc actctctata
     8461 tcactgtcat cacaacgatc aattctttcc aatgctttgc cttgattcag ctgttgacct
     8521 ctggtggtcc caactattca accagcactc tgatgtacta tctttacgaa aaagccttca
     8581 agctatcgga atacggctat gctaacacga tgggggtttt cttggctatc ttgattgcac
     8641 tgatcagctt tgcccagttc aaattcttgg gtaatgatgt ggaatattaa aaggagcttg
     8701 acatgaagaa aaagaaatta acagcatcag atatcctaac aacagccatt ttgtgtttat
     8761 taacaatatt atttattttc cccttttatt ggatcatgac aggagccttc aaatctcagc
     8821 cagatactat tgttgttccg ccacaatggt ggccaaaggc accaacaatt gagaatttta
     8881 aagccttgat tattcaaaat ccggctctta aatggctctg gaacagtatc tatatttctg
     8941 ttgccaccat gcttttggtt tgtggcacct cttccttggc aggctatgct ttagcaaaaa
     9001 aacggtttta tgggcaacgc ttattgttct caatctttat tgccgctatg gctctgccga
     9061 agcaggtggt cttggtgcca ttggttcgta ttgtgaattt tatgggcatt cacgatacgc
     9121 tagcagcagt tattttgcct ttggtgggct ggccttttgg ggtattcctg atgaagcaat
     9181 tttcagaaaa tatcccaaca gagctattag aatctgctaa aattgatggc tgtggtgaaa
     9241 ttagaacctt ctttaacgtt gcctttccaa tcattaagcc aggctttgct gccttagcga
     9301 tttttacctt tattaatacc tggaatgact actttatgca gctcgtgatg ctcacatcac
     9361 gcgataacct gaccatctct ctaggggttg ccaccatgca ggctgagatg gcaacaaact
     9421 atggtttgat catggctggt gcagctcttg cagcagtacc gattgttaca gtctttcttg
     9481 tgttccaaaa atcctttacc caaggtatca ccatgggagc tgtgaagggc taatatagcc
     9541 ttagaaaggt caggagatta tgctctatga tgtcttggaa aacattcgtc gctataaggg
     9601 gatccatcat catttggatt tagccattga ctttttgatg acaagagatt taaggtcact
     9661 cacagatggc aagcatgtga ttttagagga taaggtggtt ctctttattc agcataattg
     9721 tctcaataaa gaggataatg ccttgcttga ataccataag cgctatgccg atttgcatct
     9781 actagtcgag gggaatgagc gagtacgcta tggcttaggc tacaagcagg aggctgttag
     9841 ctttgatgag gcatcagaca tcggctttgt gacctgcgag aggacttatg acttggactt
     9901 gggaaatgat tgtttttgct atttctttcc caatgaagct catcagccta atggctttaa
     9961 cgacggtggt gatgctgtca caaaatgctt gattaaggtg ttgatggaag attaactaga
    10021 aaggataggg agtaatgata tgagcagcaa aaaaagaaag ctagtgcagt ccatttttag
    10081 cttggatagc aaatggctga gggctagtgc tactatcttt gaccttatcg tgctcaattt
    10141 gctttttgtg ctgtcttgct tgcctgtggt aacgattggc attgccaaaa tcgccttgta
    10201 tgctagtctg cgagattacc ggcaaggaga tatcggctct gttgtaggcg tctacggctc
    10261 ttatctacgg cggtttgcca agagaggcct tcaattaggg atcctagaag tgctcttgac
    10321 gagctttatc ttggttgacc tttatctcat tcaggctcag gtgtcgcttt tctttcaact
    10381 atttaagatt agctgtatag cgatattatt tgtggctatt atggtctttt tgtatgctta
    10441 tcctttagct atgcgatatg atttgcctct tatgtcatta tttcagcgaa gctttatctt
    10501 gcttagtctt ttcttcccct ttagctttgc ttttttagct gttatgctgc tagtggtctt
    10561 tttgctgcag ctatctccgc taagtctatt aggagggctg tcgcttttag ccattattgg
    10621 cattagcagc ctaacctatc cttatgtcgt cattatggaa aaccttcttc aaaaggtaca
    10681 acttcattaa aaataagatt tagaaaaaga gtgtcattat gaaaacttta accaaatatc
    10741 aagggattat ccctgccttt tacgcctgct acgacgctga gggcaatatt agtccagagc
    10801 gtgttcgtgc tttgacacaa tattatattg ataagggtgt ccaagggctt tatgtcaatg
    10861 gctcatcagg cgagtgcatt taccaaagtg tggctgatcg taagttggtc ttagagcatg
    10921 tgatggcagt agccaagggc aagctaacca ttatcaatca cgttgcctgc aacaatacca
    10981 aggacagcat tgagctggct cagcatgctg aggccttggg ggttgacgct attgcagcga
    11041 ttccaccgat ttatttccgt ttgcctgagc atgctgtggc tgcttattgg aatgcgattt
    11101 cagctgctgc tccaaatact gattttgtga tttacaatat tccgcaattg gctggtattg
    11161 ccttgacccc aagtctctat caggaaatgc ttaaaaacga gcgggtcata ggggtcaaaa
    11221 actcctccat gcctgttcag gatattcaaa cattttgtgc tatcggaggt gatgatcacc
    11281 ttgtctttaa tggaccggac gagcaattct tagggggacg actcatggga gcctctgctg
    11341 gtattggtgg tacctatggg gcgatgccgg agctcttctt acgcttaaat caattgatca
    11401 aggacaagga cctagaaact gctaaggccc tacagtatgc tatcaatgat attatcgggc
    11461 tattggtttc tgctcatggc aatatgtatg gtgtcatcaa ggaggtgctg cgcattaatg
    11521 agggtctgga tattggttct gttcggtcac ctttaccaga gctaacagag gctgatttgg
    11581 tgatctgtca gcaggctgca gccttgatta agcagaccaa ggaacaattt tgctattaaa
    11641 atgaggtgat caaatgaagc attatcttgc tattgacatt ggcggtacag ccatcaagta
    11701 tggccttatg acagagacag gagatttgct tgaaaagcat gaaatggcta ctgaggctca
    11761 taagggcggt cctgctattt tagacaaggt caaggacctg gttgcagcct atcaggaggc
    11821 tggactagct ggtgttgcga tttcttcagc tggcatggtg gatcctgata agggcgaaat
    11881 cttttacgca gggccacaaa ttccgaacta cgcaggcacg cagtttaaaa gggtgattga
    11941 agagaccttt ggcattccct gtgaggttga aaatgatgtc aattgtgccg gtctagcaga
    12001 ggctatttct ggcagtgcca aggattgccc tgtagccctt tgcttaacca tagggacagg
    12061 aattggcggc tgcctgctga ttgattcgca ggtgtttcat ggcagcagct actctgcctg
    12121 tgaggtaggc tatattcatt tgccggacgg tgcgttccag gatttggcct ccacaacagc
    12181 tcttgttaga gatgttgcta ggcgtcatgg tgacccagtc agtgcttgga atggtcgtcg
    12241 tatttttgaa gaggctaagg caggcaatca ccattgtata gcagccattg accagttagt
    12301 tgactatcta gctcaagggc ttgccaatat ctgctatgtt gctaatccaa atgctattgt
    12361 cttaggcggt ggcattatgg ctcaaaagga ctatttgcag gataaaatcc tagctgccct
    12421 caataattat ctggtaccta gcattgcaga aaagacccag attcgatttg ccagccatga
    12481 aaacaatgct ggtatgattg gggcttacta ccatttcaag cataaggagc aagtctaatg
    12541 atagaaacca tgtcacttga agagatgatg tcctacaggg ggcgtcacga ggtgcccaag
    12601 gattttgatc atttttggga gacctgtatc aaggaaaatc aagctgcctc ttatcagctt
    12661 gatcaaaagg attttggcct tgattttgct gattgctatg agttgcgttt taaaggtagc
    12721 aatggctcaa ccatctatgc taaatgtgtc tttccaaaag ccaagcagct agtcccagtt
    12781 gtcttttatt ttcatggcta ccagggtcag agcccagact ggagtgatca gtttaattac
    12841 ctagcggctg gctatgctgt ggtctcaatg gatgttcgcg gacaggcagg ctattctcag
    12901 gatttaggtc agtttgatgg cattaccgtc aagggacagg tcattcgcgg catgacctca
    12961 gggccagagc agctttttta taaggacgtt tatttagatg tttaccagct gatcgatata
    13021 gtgtctgctt ttgctcgtgt tgacgatagt cgcttgtata gctatggctg gtcacaagga
    13081 ggtgcgctat cactcattgc agcagctctg caccccaaga ttgctaagac agttgctgtt
    13141 tatcccttct tgtcagattt taagcgtgtc ttagagctag gcaatcatag tgagccttat
    13201 gatgagctgt ttcgctattt caagtaccat gatccttttc atgatactga ggctgaagta
    13261 ttgggaaacc ttgcttacat tgatgtgaag aattttgctc acttgattac ctgtcctgtt
    13321 gtcatgctga cctgtatgga ggacgttatt tgtccaccgt ctacacaatt tgccatcttt
    13381 aatcgattgg caacagctga caaatgtcat aaacttattc ctgactacgg ccatgaccca
    13441 atgggagtca aggttaagga ctttattttt gaccagctga ccggcagcca ttttaccaag
    13501 gcatagctgg tatgctgctt attcttattt gttaaccatg aggctttaga aaagcttacc
    13561 cattcgcttt ttcactcctt gcctctaata tacaagcacc tcaatgacat tagccacagc
    13621 tagctagggt cattgaggtg cttttttgtg atgctattta tctgaaggat tgataatcgt
    13681 ctcttggaaa atttttgtct ttccttcctt attgatttct aaaaaataag cgtagataat
    13741 atccgttaca aagagcattg gaaattgtgg tgagatacga ttgccatagt taaggtgacg
    13801 agctgtagcg atatgcacaa tttcgtcaag ctggtaaggg atctcatcgg tctgggttgt
    13861 gagcagcact gtcttggcgc cacgtgtccc agcagtttgc agagcctcta agacggatgc
    13921 tgtttgagca gagagtgaaa aaccaataac caagcattta tctgtaatgc tgctgttaac
    13981 ccaggtgaag ctatcagtgt catctaaggc ctcgcaaata acaccaagtc gcatcagacg
    14041 gagcttgaat tctttggcgg caagagctga gctgccctta ccgtaaaaat aaatccgctc
    14101 ggcattttca atccattgtg caatgtcctg tagctgcttt tcgttgatca gctcggtagc
    14161 cttttcgatc aattcgcggt agttcataag gacttttttg gtgttggaat tttgcaggtt
    14221 gggtgccttt tgatccattg cctcacgact tttttgacat tcaaaaacaa attcgcgata
    14281 accggtaaag ccacattttt tggcaaagcg tgttaaggct gcctgcgaga cgtgaagcct
    14341 tttaatcatg tctgaagctg ttagctcttc gacctttagg tctgtttcca taaaaaattg
    14401 agcgatgctt ttttctaagc tagtcatgct gtctagtgca gcttccattt tgctgattaa
    14461 acggtgattg tgtatcatat gaactccctg atgtaaggct gtctattata atagtatatc
    14521 ataaaaagga aaaagataaa gaatacagat aatataataa tatagagctg atattacagt
    14581 tatgtcaagg ctgactgttt gagtaaacca agagctatgc taagaatgaa gtagctgatg
    14641 agatatggta taataatcaa gcaggtatcc cttttagggc aatacaagaa agaggaatga
    14701 ctaagaatga tagaaatttt tgatacccat acgcatttga atgtggatca ttttagtggt
    14761 aaagaggaag aggaattagc acttgctaag gagtttgggg ttagctacca taatgtcgtt
    14821 ggctttgatc aggagactat tgatcaagcc cttaccttag ctgatgctta tagggaggtc
    14881 tatgcaacga ttggctggca cccgactgag gctggctctt acacacaggc ggttgaagat
    14941 aggctgattg cttgcttgaa gcacccaaag gttgttgcct taggagagat tggcttggat
    15001 tattattgga tggaggaccc caaggaggta cagatagagg tttttaagcg tcagctgcag
    15061 cttgctaagg accatgacct tccttttgtg gtgcacacgc gtgatgccct tgaggatacc
    15121 tatcaggttt taaaggaggc tggagtaggg cctaggggtg gtatcatgca ttcctactca
    15181 ggctcgcttg agatggctca acggtttgta gatctgggta tgctgatttc cttttcaggg
    15241 gttgtcacct ttaaaaaggc ggttgatgtg caggaagcag caagacacct gccgctggat
    15301 aagctcttgg tggaaacaga tgccccctac ctcgccccag taccaaagag aggacgtgaa
    15361 aaccataccg cctatacgcg ttatgttgtt gagaaaatcg cggagctacg tggtttatca
    15421 gtagaagaga tagctgcagc aacgactgcc aatgcaaaga gggtgtttag gattggctga
    15481 gaagctaaaa attcacgagg ttattgtggt agagggtaag gacgacaccg ctaatttaca
    15541 gcgcttctat gatgtcgata cctatgaaac aaagggttct gccatcactg atgaggacct
    15601 agagcgcatt gatcggctta acaagctgcg tggcgtgatt gtctttacgg atccagatta
    15661 taatggcgag aggattcgta agctgattat gggagctgtc ccaacagctc gtcatgcctt
    15721 tttacatcga catgaggcta agccaaggtc caaaagtaag ggacgttcct taggtgtgga
    15781 gcacgctagc tttgaggacc tgcaaaaggc tctgtctcag gttacccagt cttttgatga
    15841 cgagagttat tttgatatta gtcagacaga tttgattcgt ctagggcttt tattggcagc
    15901 tgatagccgc aagcgcagag agtatctagg agaagtcctt cgtatcggct attccaacgg
    15961 aaagcagctc ctaaagcgcc taaagctatt tggcattacc ctatcagagg ttgaggacgt
    16021 gatgagctcc tatcagactg agcaatagat ggcgctagaa aggctgattg gatcaaaaga
    16081 gccctgagac ttcttgttct ggctccaaaa aattagataa gaaatggtaa caaggattga
    16141 attctgtatt gggcaggagt cagtcctttt aactttctta gataagcatt ctctgttcta
    16201 agacgttcat tctccttgaa gttgctctag ttctccagat gttctttgat tgatgtcctc
    16261 tcttgcttgg tctccctctt gttttatcaa gaatagtata accattttca tctctttttt
    16321 tgctgtggct ctgataaacc atagaaatat gctacaatag atataaaaca atgaatagga
    16381 catcaacatg agaattgcag attacagtgt gaccaaggct atccttgatc gctatggctt
    16441 tacctttaaa aaatcatttg gtcaaaattt tttgacggat actaatattt tacagaagat
    16501 tgttgatacg gctgagattg acaagtcagt caacgtcatt gagattggtc ctggtatcgg
    16561 ggccttgacc gagtttttgg cagaaagggc tgcagaggtt atggcctttg agattgatga
    16621 gcgcttggtg ccaatactgg ctgacacgct tcgtgatttt gacaatgttc aggtggtgaa
    16681 tcaggatatt ttaaaggcag atttacagac ccagttaaag caatttagcc atccggatct
    16741 tcccatcaag gtggtggcca atctgcccta ttacatcact acacccattt tgatgcacct
    16801 gattgaaagt aagattccct tccaagaatt tgtcgtcatg atgcagcgcg aggtggcaga
    16861 tcggatttca gctgagccca ataccaaggc ctatggctct ttgtctatag cagtccagta
    16921 ttatatgacc gctaagatag cctttgttgt tcctaggact gtttttgtgc cagcaccaaa
    16981 tgtggattcg gcaattctga agatgactcg tcgtgaccag cccttgattg aggttcaaga
    17041 tgaggatttc ttttttaggg tgtcacgagt aggctttgtg catcgcagaa agacgctttg
    17101 gaataacttg gttagccatt ttggcaaggc tgaggacaca aaggcaaggc ttgagcaggg
    17161 actagctcta gctggaatca agtcttctat ccgaggagaa gcgctgtcta ttcaagattt
    17221 tggacggtta gctgatgccc taaagcaagt aggcttatag tgccttagtt atgattgtag
    17281 cttgtcacag caatcctgct gtggcttttt tagatagtgg taggctgatc ttatctttgg
    17341 tgaaacttgg gctaaactgc tgaattcgaa tgatttttct gatataatgg cattattcta
    17401 ggatagaaaa aggagttcat ttgcaaggca aaatcattaa ggctctggct ggcttttact
    17461 atgttgagtc agaggggcag gtttatcaaa cgcgggcgcg tggcaatttt agaaagcgtg
    17521 gtcaaacacc ctatgtagga gatttagtag aattttctgc tgaggacaat tcagagggct
    17581 atattttagc cattgctgag cgaaaaaata gtctggtgcg tcctcccatt gtcaatattg
    17641 atcaagcagc tgtcattatg tcagccaagg agcctgactt taatgccaac cttttagatc
    17701 gctttctcat tttacttgag cacaaggcca tccaccctat tatttacatt tcaaaaatag
    17761 acctgcttga gcagccagag agtattgaag ccattggtca gcattatcgt gcgattggct
    17821 atgattttgt gacgagctta tcacatctcc tgccattatt agctggtaag acaacagtat
    17881 ttatgggaca gacaggggtt ggaaagtcca ctctgctaaa ccggatcgta ccagagctag
    17941 cccttgaaac gggtgatatt tcagacagtc tgggacgggg acgccatacc actagagctg
    18001 ttagctttta tgacgcttac aatggcaaaa tcgcagacac acccggcttt tcgtccttgg
    18061 actatggcat tgataatgct gaggacctca acgaagcctt tccagagctt agacacctta
    18121 gccatagctg caaatttcgc tcctgtaccc atactcatga gcccaagtgt gcggttaagg
    18181 aagccttgga aaatggtgag ctctggtctg ttcgctatca gaattacctt caatttctga
    18241 gtgaaatcga aaaccgtcgg gaaacatatc aaaaagttag taaaagaaag taggtttaac
    18301 catgtcatct ctgaaaattg cgccatctat tttagcagcc gactatgctt gctttgctgc
    18361 tgagctggcc cgtattgaaa aaacaaatgc tgaatacgtt catattgata tcatggacgg
    18421 tcagtttgtg ccaaatatca gctttggggc agatgttgtt gctagcatgc gtaagcacag
    18481 caagctagtc tttgattgcc atttgatggt tgtgaatcct gagagatatg ttgaggcctt
    18541 tgcccaagca ggagctgata tcatgaccat tcatgtggag agcactcttc atagtcatgg
    18601 tgccttgcaa aagatcaggg ctgctggtat gagggctggt gtggtgatta atcctgggac
    18661 acctgtctct gcggttgagc ccttattaag cctggtagat caggtgctga tcatgactgt
    18721 taatccaggc tttggaggac aggcctttat tccggaatgt ctggaaaagg ttgcagctat
    18781 tgctaaaatg agagatgaaa gaggcttgag ctttgatatt gaggttgacg gtggtgttga
    18841 tgataaaacc attcgtgctt gctatcaagc aggagctaat gtttttgtgg ctggctccta
    18901 tctgtttaag gcagcggatt tggcagctca agtgcaaaca ttgagggcgg ctcttaatgg
    18961 ttaaggtagc cctctttgca ggtggggatt tgtcctattt tacctgtgat tttgattatt
    19021 ttgttggaat tgatagagga agtctatttt tgttagaaaa tgggcttcct ttgaatatgg
    19081 ctgtaggcga ttttgattca attccccaag tagcctttga ggttgtcaag gagcaagcag
    19141 agcttcttgt tcaggctagt cctgaaaaaa atgatacgga cactgaatta gctctcaaag
    19201 aggtatttac ccgttttcca gaggcagagg ttacgatctt tggtgctttt ggcggtagat
    19261 tagaccactt gttgtccaat gtctttttac cagcggatcc agagcttgca ccgtttatgg
    19321 cacaaatttg cctgcgggat cagcaaaatg ccatcagcta tcgatcctct ggctggcaga
    19381 cgattaggca ggataaggac atgacttatg tggcctttat ggctgatggt gatgctgact
    19441 tgaccattac aggtgccaaa tttgatttga cgacgtccaa tttctttaag aaaaaggtat
    19501 acgctagcaa cgagttcatt gatcagccca tcagggttca tgtgccaaag ggctatttag
    19561 ttattattca gagcaaagat aggagttagt atggacctta ttcttttagt gttagtgctt
    19621 gcgttgatag gacttgctgc ctattcattt gttagcataa agcatttgca gagcaggcta
    19681 gaaaaagcct tagacaataa tgctgataat ctatcagatc agctaaccta ccagctggat
    19741 atggcaaata agagtcagct gctagagcta tcaacagtga tgaatcgtca gcaaaatgag
    19801 ctttttcagc agctgatgga tattcgtgat acgctgcatc agggcttggc tgaaaatcgc
    19861 gaccgctcag accagcgttt ggaaacgatg acgcaaagcc ttagccaagc tgtcaagaac
    19921 ctacaggatt ctaatgaaaa gcgactggag gaaatgcgtc acaccgtcga agaaaagcta
    19981 gaaaaaacac tgaaaaatcg gttgcagacc tcctttgaag ccgtttcaaa gcagctggaa
    20041 agtgttaatc agggtctagg agaaatgcgg accgtagcta aagatgtcgg taccctaaac
    20101 agggtcttat ccaataccaa aaccagagga attctagggg agctccagct tggtcagatt
    20161 attgaggaca tcatgacagc taaccagtat gaaagagagt ttgccacagt ttctggctca
    20221 agcgatcgtg tcgaatatgc tatcaagcta cctggaaatg ggcaaggaga ctatatttac
    20281 ctacctattg actccaagtt tcccttggag gactattaca ggctggagga tgcttacgag
    20341 gctggtgatc gaacggctat tgagactagc cgaaaggctc ttcttgcggc gatcaaacgt
    20401 tttgctaaga gtattcatag caaatacctg agtccacctg aaacaaccaa ttttgggatt
    20461 atgtttttac caaccgaggg gctctactca gaggtggtgc gcaatccggc tttctttgat
    20521 agccttcgtc gtgaggaaaa tattgttgtg gcaggcccat caaccttatc agccttgctt
    20581 aattccttat ctgttggctt taagaccctt aatctacaaa aaaacgcaga cgatattagc
    20641 aagattttag gcaatgttaa attagaattt gaaaaatttg gcggtctgct tgctaaggcg
    20701 caaaagcagc ttaacactgc taaccatacc ctagatcagt tgatgtcaac tagaaccaaa
    20761 gcgattgttc gtgctctggc tactgttgaa gactaccaag atcagtcaac ccaatcctta
    20821 ttacatatac ccttattaga agaggcagac gatgaagatt aaccaaatga aaaaagatca
    20881 gccctttgaa ggcttttacc tgataaaatc agcagaagtc agaaaaacaa gagctggcaa
    20941 ggattttatt gcttttacct ttcaagatga tactggtgaa atttcaggca atttgtggga
    21001 cgctcagcct tataatgttg aagaatttgt cgcaggtaag attgtcttta tgagaggccg
    21061 tcgtgaggtc tataatggta ctcctcaggt gaaccaaatt accctaagaa atgtccgacc
    21121 aggtgagcct aatgacccaa aggaatttaa agaaaaggca cctgtcagtg ttactgaggt
    21181 tcgtgactac cttgatcaga tgctctttaa gatcgaaaat gcgacctggc agaggattgt
    21241 tagagcactt taccgcaaat atgataagga gttcttcact tatccagcag ccaaaaccaa
    21301 tcaccatgcc tttgaatcgg gcttggccta tcatacagca acgatggtta ggctagcaga
    21361 cagcatagga gatatttacc cggagctgaa taaaagcctc ttatttgcag gcattatgct
    21421 gcatgatcta gccaaggtgc ttgagctgac aggaccagac aataccgaat acactatccg
    21481 aggcaatctg atcggacata tcgctcttat caacgaagaa atcaccaaga ccatcacaga
    21541 gctcaatatt gatgacaaca aagaagaggt cactgtttta cgtcacgtga tcttaagcca
    21601 tcatggtcaa ttagaatacg gcagccctgt tcgtccacga atcatggagg cagagattat
    21661 tcacatgatt gataacattg acgccaatat gatgatgatg tcaacggcgc ttagccgcgt
    21721 tggcgaggga gaaatgacca atcgtatttt cgctatggat aaccgatcct tttataagcc
    21781 taaatattag caaagattat aataaaaaac gaacattttg cagttgaatg ttcgtttttt
    21841 cgttatgtta tgatataata gtagagaata tacaaataat ggggaacata tgaaattaag
    21901 acgaagtgaa cgcatggttg ttatttcgaa ttacctgatt aacaaccctt acaaactaac
    21961 gagtttaaat acctttgcca caaagtacga ggcagctaaa tcatctattt cagaagatat
    22021 tgccattatc aaaaaagcct ttgaagaatc taatattgga gagattgaca ctctaacagg
    22081 ggcaagtggt ggtgtcattt tcacgccaag tatttcagag gcagaggctc gctcaatcgt
    22141 agaagagctg tgtcagcggc tttcagaaag caaccgcatt ttacctggtg gctatatcta
    22201 tctgtctgat ttgttaagca caccaaagct cttacagaat atcggtcgca ttatcgccaa
    22261 tgcttttaag gggcaaaaga ttgacgcggt gatgacagtt gcaactaagg gggttccctt
    22321 ggctaatgca gttgcgaaca ttctgaatgt gccatttgta attgtaagac gcgacttaaa
    22381 aattacagaa ggttcaaccg tctcagtcaa ctatgctagt gcttcaagtg atcgcattga
    22441 aaagatgttt ttatcaaagc gaagcttaaa gccaaacagt cgagtcttga ttgttgatga
    22501 ttttttaaag ggtggtggta cgatcacagg catgatgagc ctgttaacgg agtttgatag
    22561 tacattggtg ggtgtagctg tttttgcaga aaatgcacaa tcagagcgcg aacaaatgtc
    22621 cttcaagtca ctattaaagg tctccgaaat tgatgtcaaa aataataggg tcgttgttga
    22681 agtaggaaat attttcgata aataaatcga acgtaggtgg aaaaataaaa ggggattaat
    22741 catggaacaa gaaaactcaa gaacaaagca tgttaaaagt accattgctt tgacatcaac
    22801 cattgcccta ttagggacaa gcgttggtgt atcgtaccag gtaaaggcag atgatacgag
    22861 ttcaggcaat accaacacaa gcaatgccaa cgaaggcaat ctagctaagc cagaaacgct
    22921 tgaggaggcg gtccttgcgg taaaggctac agaagaaaca ctcagtgagc agaaaaaaga
    22981 attagctgag gttgatacac aggctacaaa agcagaagct gaaatagcag ctttagaagc
    23041 aactaaaaaa gagcaggcag ctgatcttgc caaggctgaa gagatacttg agacctactc
    23101 atccatgagt gaggaggact tagctaagtc cattgaaaag catgaggcag agcttgagac
    23161 agtcagctca gagctagagc aggtgactgc tgatggtcaa gctcaggcag aggcagtagc
    23221 taagcagcaa gaggcaatcg taacagagac cgctaccgct aatcagctat cagagcagct
    23281 ggcagcagca gagcaaaagg tctcagacct taacacaatg attagccagc cggaagctat
    23341 tgtctcagaa gctcaggctg caaaagaaga ggtcaagcgc atttctgatg acctagcaaa
    23401 ggctacagca aatctagcta ctgttaagga cacagtccac agccagctaa cctcagacct
    23461 agcagccaac aaagcagccc tggcagctaa agaggcagag ctgcaaaggc ttcaagatgg
    23521 aactgccact gctcaattga acgttgctgg cagcaataaa ttagtcttgc ctgaaggcta
    23581 cccaattgag gagattaaaa agctagcagc cagtggttat atcggaacag cagcatataa
    23641 tcaatattat caggcagtta aggatacaat gattgcaaag gcagagccgg gtgctgctat
    23701 gaatcagtat gttgatattc ctgaggacct caatcgtgtt gttgaccctg ataacctgcc
    23761 agaagatatt caaaatgagc tggctcagtt tgcagctcaa atgatcaatg atgtccgcaa
    23821 gcagctaggt cttgtccctg taacagtaac agtcggctca caggagtttg ctcgcctgct
    23881 aaccaagagc tacaaagcga cacatcaaaa tactcgacct tcctttgtct atggacaagt
    23941 agatgcttca ggtcatcgcg gtgtaggtcc gcatgatgaa acgattattg aagaatctgc
    24001 tgtaaaggta ggacttcgtc aaaaagatga caacatgtac gaaaaccttg gtgcctttaa
    24061 cgaggttcac actgtcaacg gtatcaagcg cggcatctat gacagcatta agtatatgct
    24121 gtttacagat cacctgcatg gaaacaccta tggccatgct gttaatttcc tgcgtgttga
    24181 taagactaac cctaatgcac ctgtttacct aggattttca acaagtaatg ttggctcctt
    24241 aaatgagcat tttgtgattt tcccagcgtc agatattgtg gacgctactc gttttagcac
    24301 gactgaaatt ccaaaatcag gtcaagtgat tgatcgctca gcaagcatac aggcattgac
    24361 aaatgatatt gcctctatca agggcaagat tgcgtctctt gaaagcagat tagctgatcc
    24421 ttcctcagaa gctgaggtca cagctgcgca ggcaaaaatc agtcagctgc aacatcagct
    24481 agaagcagcc caagccaaat ctcataaatt ggatcaacag gttgagcaat tagccaatac
    24541 aaaagattct ctacgcacac agttgcttgc tgccaaagaa gagcaggcac aattgaaggc
    24601 taatctagat aaggccttgg ccttgctagc ttcttcaaag gctacgcttc ataagcttga
    24661 agcagctatg gaggaggcta aggcaagagt ggctggctta gctagtcaga aggctcagct
    24721 tgaggatctg ctagcctttg agaaaaatcc taatcggatc gagcttgcac aggaaaaggt
    24781 agccgcagcc aaaaaggctt tagctgatac agaggataag ctcttagctg ctcaggccag
    24841 cctgtctgat ttgcaggctc aaagagcaaa actccagctt tctattgcga caattgaaca
    24901 acaattagta ctattgaaga atttagtcca agaaaagcaa aggctcagac ttgaggctga
    24961 aaggctaaat agcatgtcag aaacaagaca gcttctcaat cagctagcgc cgcaggctgc
    25021 aaaagcaggt gtcggctcag aattggttgc tacaggtctt cttgtctcca aggttgcctc
    25081 agctatcgct aagcaatcgc cgataagcca ttcctatgga gcaggagcag catcacatgc
    25141 ggctgttgat gacaacacac agcgtgctgt tcaggctggt atggtcatgc tggcaactgc
    25201 cggcttagca acggttaagc tcaaaaaagg cagcaaaaaa cgctaagcct agcttaaaaa
    25261 gcatttgaca caaggtatcg tctatgttat tatattagac ggtacttttt acttttggtc
    25321 tctcaagagt gtacagagac gtgctgacaa ttgttgcaaa aagtgcacca gatataggct
    25381 gtcaccaagt gctatatcaa ccaaaattaa aaaaacagga gaatgtagat gcctacaatt
    25441 aaccagttgg tacgtaaacc acgtaaatct aaaattgaga aatcagattc gccagctttg
    25501 aacattggct acaacagtca taaaaaagtt catacgaagc ttgctgctcc acaaaagcgt
    25561 ggtgttgcga ctcgtgttgg aacaatgaca cctaaaaaac ctaactctgc ccttcgtaaa
    25621 tttgcgcgtg tacgcttaag caaccttatc gaagtaacag cttatatccc aggtattggc
    25681 cacaatctac aagagcacag tgttgtgctt atccgcggtg gacgtgtaaa ggaccttcca
    25741 ggggtacgct atcatatcgt tcgtggagca cttgatactg caggtgttgc agaccgtaag
    25801 caaggccgtt ctaagtacgg tgctaaacgt ccaaaaggat aatagaggag ggataagaaa
    25861 caatgagtcg taaaaataga gcgccaaaac gcgaagtatt accagatcca ttatataact
    25921 caaagcttgt gacgcgtctt atcaatcgta ttatgcttga tggaaaacgc ggaactgcat
    25981 catcaatcgt ttatgatgct tttagcgaaa tcaaagaagc aacaggcaac gatgctcttg
    26041 aagtatttga aacagctatg gacaacatca tgcctgtgct tgaagtgcgt gcacgtcgtg
    26101 tcggtggttc aaactatcag gttccggttg aggttcgtcc agagcgtcgt acaacacttg
    26161 gtcttcgttg gttggtaact gcatcacgtg ctcgtggtga acacactatg aaagatcgtc
    26221 ttgcaaaaga aattatggac gctgcaaaca acaccggtgc gtcagtcaag aaacgtgagg
    26281 atactcataa gatggctgaa gctaaccgcg cctttgcaca cttccgttgg taatataagc
    26341 tgtgagcatg ttaagcagtg tcaagacagg atagaaaaac gaataaagaa gctacggctt
    26401 ctagacagct tttctatttg tcaggctctg tcatgcagac acgatgacgt cagacaagag
    26461 gctgtctaga gcactcagca aaaataagag gtatgccaaa gagtctttgg attttagatg
    26521 gaccttgcct ttttgcttgg cacttagact gagtttgatg acaactgaaa aaccattgaa
    26581 acgggtaggc ctctgcctat ccgtttttaa tgaatagtgt tataataaga tgtaaataaa
    26641 aatataggag aaaaaaccta atggctcgcg aattttcact agcaaaaact cgtaatatcg
    26701 gtatcatggc tcacgttgat gctggtaaga caactacaac agagcgtatc ctttactaca
    26761 ctggtaaaat ccataaaatc ggtgaaacac acgaaggtgc atcacaaatg gactggatgg
    26821 agcaagagca agagcgtggt atcacaatca cctctgctgc tacaacagcc caatgggatg
    26881 gacatcgtgt taacatcatt gatacaccag gacacgtgga cttcaccatc gaagtacaac
    26941 gttcgctccg cgttcttgac ggtgcagtaa ccgttcttga ctcacaatca ggtgttgagc
    27001 ctcaaacaga aactgtttgg cgtcaagcaa ctgaatacgg tgttccacgt attgtttttg
    27061 ccaacaagat ggataagatt ggtgctgact tcctttactc agtacaaacc cttcacgatc
    27121 gtcttcaagc aaatgctcac ccaattcaat taccaattgg ttcagaagat gattttcgtg
    27181 gtatcattga cctgatcaaa atgaaggctg aaatctacac caacgacctt ggtacagata
    27241 ttcttgaaga ggatattcct gaggaatacc tagagcaagc tcaagaatac cgtgaaaagc
    27301 ttatcgaagc agttgctgaa actgacgaag atttgatgat gaaatacctt gaaggtgaag
    27361 aaatcactaa cgaagagctt gttgctggta tccgcaaagc aacaatcaac gttgagttct
    27421 tcccagttct ttgtggctct gccttcaaaa acaaaggggt tcaattgatg cttgatgcgg
    27481 ttattgcata ccttccaagc ccacttgaca ttccagcaat taaaggggtt aatcctgata
    27541 ctgacgctga agaggagcgc ccagcatctg atgaagagcc atttgcagcc cttgccttca
    27601 agatcatgac tgacccattt gtaggtcgtt tgaccttctt ccgcgtttac tctggtgttc
    27661 ttaacagtgg ttcatacgtg atgaatacct caaaaggtaa gcgtgagcgt atcggacgta
    27721 tccttcaaat gcacgctaac agccgtcaag aaattgaaac agtttacgct ggtgacattg
    27781 ctgctgctgt tggtctgaaa gacactacaa ctggtgactc attgactgat gaaaaagcaa
    27841 aaatcattct tgagtctatt gaggttccag agccggttat ccaattgatg gtagagccta
    27901 agtctaaggc tgaccaagat aagatgggta ttgcccttca aaagcttgct gaagaagatc
    27961 caaccttccg cgttgagaca aacgttgaga ctggtgaaac agttatcgct ggtatgggtg
    28021 agcttcacct tgatgtcctt gtagaccgta tgcgtcgtga attcaaggtt gaagctaatg
    28081 taggtgctcc tcaggtatct tatcgtgaaa ccttccgcgc ttctacacag gctcgtggct
    28141 tcttcaagcg tcagtctggt ggtaaggggc aattcggtga cgtttggatt gaatttacgc
    28201 caaatgaaga aggtaaagga tttgagtttg agaatgccat tgttggtggt gtggttcctc
    28261 gtgaatttat cccagccgtt gaaaaaggct tgattgagtc tatggcaaac ggtgttcttg
    28321 caggctaccc aatggttgac gttaaagcta agctttacga tggttcatac catgatgtcg
    28381 actcatctga gactgccttc aagattgcgg cttcacttgc ccttaaagaa gcagctaaaa
    28441 cagcacagcc agctatcctt gagccaatga tgcttgttac aatcacagca ccagaggata
    28501 atcttggaga tgttatggga catgtgacag ctcgtcgtgg gcgtgttgat ggtatggaag
    28561 cacatggtac tagccaaatt gttcgtgctt atgtgccact tgctgaaatg tttggttatg
    28621 caactgttct tcgttctgca acacaaggac gtggtacatt catgatggta tttgaccact
    28681 atgaggacgt tcctaagtca gttcaagaag aaatcattaa gaaaaataaa ggtgaataat
    28741 caccactagg aggctgtgga tagtatccca gcctttttga tgtgctacaa cagatgggcg
    28801 gtgaagcaat tgatcaaagt aatgacagaa aaattaagcc ctatcagcta taagagctca
    28861 gaaaagatgc tcaggaagca ctttcaacca catcaagtga cacgtttagc tgtcctaaaa
    28921 agatctttgc aggctcacca ttgctggaga agcagtcttt tgaaaatggg taatatgttt
    28981 gcattttttc tgaaatagtt atataatagt tacgttgaag ggttgttgca ggaatctgca
    29041 agttaatctt ttcacaatag gtagggatta gtccctttaa taataattct tttgattttc
    29101 ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg tcgtatcggt
    29161 cgtcttgcgt tccgtcttat ccaaaatgta gaaggtgttg aagtaactcg catcaatgac
    29221 ttgacagatc cagcgatgtt agcacatctt ttgaaatatg attcaactca aggacgcttt
    29281 gatggcgacg ttgaagtagt agaaggtgga tttaacgtta acggtaaatt tgttaaggtt
    29341 tctgctgaag ctaaccctga aaacattgac tgggcttcac aagaagtaga tatcgttttg
    29401 gaagcaactg gtttcttcgc ttcaaaagct ggtgctgaaa agcacttaca tgctaatggt
    29461 gctaagaagg ttgttatcac tgctcctggt ggaaacgatg ttaaaactgt tgttttcaac
    29521 actaaccacg aaattcttga tggtactgaa acagttatct caggtgcttc atgtacaact
    29581 aactgtcttg caccaatggc taaagttctt caagaccaat ttggtgttgt tgaaggattg
    29641 atgacaacta tccatggtta cactggtgac caaatgactc ttgatgcacc acaccgtaag
    29701 ggtgatttcc gtcgcgcacg tgctgcagct gtgaacattg ttcctaactc aactggtgct
    29761 gcaaaagcta tcggtcttgt tattccagag cttaacggta agcttgacgg tgctgcacaa
    29821 cgtgttccag ttccaacagg atctgttact gagttagtat ctgtacttga aaaagaagtt
    29881 acagctgacg aagtgaatgc tgcaatgaag gctgctgcaa acgacagctt tggttacact
    29941 gaagatcaaa tcgtatcaag cgacgttgta ggtatccact atggttcatt gtttgatgca
    30001 actcaaacta aggtattgac agttgacggt aaacaattgg ttaaaactgt ttcatggtat
    30061 gacaacgaaa tgtcatacac tgctcagctt gttcgtacac ttgagtactt tgcaaaaatt
    30121 gctaaataat gactagaggg cctagtttac ctaggctctt ttttgtgtca tgataaaggt
    30181 tgcttatccc tcattggcta gcttattgct gaacttgcac ttaggcttaa gctgcacata
    30241 ggataagttt tttgctaacg ctttagtgat tagctgttct cagagagggt cattttagaa
    30301 accttcttaa ggtaatatgg ctatcaagct gccttctttg aactgctatg cttaggcttt
    30361 gagtttaggt cttaaaagct ttagctgggc ttttcgttgt aattactgca taaagcatgg
    30421 ctttaagctc atttccagcg caaatacttt ttttctttgc gagatgtcaa agaggagtgc
    30481 tgtaatggtc taggattatt tatattttta gctattttta gctgttttta gctgttttta
    30541 gctgttttta gctatggctc catgaaattg tgaagcgttt tcatttttat tgcttatagt
    30601 cttgacaatc tgaaatgatg gtaataaaat gagaggtgga taaataaccg tacttaataa
    30661 tgtatggaat attaggagga ttttatgaca tctaaaaaaa ttcttaacct tgtgtcttta
    30721 gggttatcgt tggttttaat ctctggctgt acgacaaatg gagagaaaaa agcagctcct
    30781 agtcaagaca aggataagca agaaaaggtt gtccgtctaa ccaatgatca gctaagggct
    30841 agggaaaata ctatggccac actctggtat cagcagtctg aagaggctaa ggctctctac
    30901 ctacaggggt accaagtggc taagcagcgc ttagatacat tattgagtca agcaactgat
    30961 aaaccatact ctattgtttt ggacattgat gagacagtgc tcgataatag tccttaccaa
    31021 gctaaaaata ttaaagaggg cacaggcttt acgccggatt cttgggataa atgggtccaa
    31081 aagaaatcag ccaaggcagt agcaggtgct aaggacttct tgcagtatgc aaatgacaag
    31141 ggcgttcaga tttactatgt ttctgacaga acgactaagc aagtagagcc gactatggaa
    31201 aatcttgaaa aagaaggtat tccagtgcaa ggcaaggatc atttcttgtt cttagaggag
    31261 ggtgtaaaat caaaagaggg ccgtcgtcaa aaagtgcaag aaacaacaaa tctagtgttg
    31321 ttatttggtg ataatttgct tgattttgca gaattttcta agacctctca tgaagataga
    31381 agaaagcttt tggatcagct gcatgcagaa tttggcagca agtttatcat cttccctaat
    31441 ccaatgtatg gatcatggga aagcagtgtc tataatggtc aaaaattaga cagtgaaggc
    31501 caaatcaaag cacgtgacaa agctttagag gcttattaaa agtcctgatt tgcgtgattg
    31561 ctatgactat gttgtggctt cctgcctgct taggtgattg tgatctgcta aaaagaggtt
    31621 tacccaaggg atttttcaag cgctttgaaa aattgtgaaa tagttaattt attgttttca
    31681 gattttatcc ttatcaaaag aattgtgtta taatagagtg tactaaaaaa tattaaggag
    31741 tctatgaaat ggctaaattg actgttaaag accttgacct aaagggtaaa aaagtgctcg
    31801 ttcgcgttga ctttaatgtc cctttgaaaa atggtgttat tacaaacgat aaccgtattt
    31861 ctgcagcact tccaacaatc aaatacatta ttgagcatgg tggtcgcgct atccttttct
    31921 cacacctagg acgtgtgaag gaagaggcag acaaggaagg caaatcattg gcgccagtag
    31981 cgaaaaactt ggctgaaaag cttggtcaag aggttatttt ccctggtagc actcgtgggg
    32041 cagagcttga agctgctatt gatgctcttg aggatggaca ggttcttttg gttgaaaaca
    32101 ctcgctttga ggatattgac ggtaaaaagg aatctaaaaa cgatccagag cttggtaaat
    32161 actgggcatc actaggagaa ggaatctttg ttaatgatgc ctttggtaca gctcaccgcg
    32221 ctcatgcgtc aaacgttggt atctctgcaa atgttgaaaa agcagtggct ggcttccttc
    32281 ttgaaaatga aattgcctat atcaaggaag ccgttgagac tccagagcgt ccatttgtcg
    32341 ctattcttgg tggttcaaag gtttctgaca agattggtgt gattgaaaat ctccttgaaa
    32401 aagctgataa ggtgcttatc ggtggtggta tgacctatac cttctacaaa gctcaaggca
    32461 ttgaaattgg aaactcactt tgtgaagagg acaagcttga tgtggcaaaa tcacttcttg
    32521 aaaaatcaaa cggcaagctt attttaccag ttgattctaa ggaagcaaac gcttttgccg
    32581 attacactga agtgaaggta actgagggtg aagcagttga tgcaggcttc cttggacttg
    32641 acattggtcc aaaatctatc gctaaatttg atgaagctct tacaggtgct aaaacagttg
    32701 tttggaatgg tcctatgggt gtctttgaaa atcctgattt ccaagaaggt acaattggtg
    32761 tgatggacgc tattgtgaag cagccaggcg ttaagtcaat catcggtgga ggtgattcag
    32821 cagcggcagc catcaacctt ggacgtgcag ataaattctc atggattagt acaggtggag
    32881 gtgcttcaat ggagcttctt gaaggtaagg agcttccagg cttagcagct cttacagaaa
    32941 aataagctga taccatttcg gtgctgtcag tcgcaggctg ctatatggtc tgttaagggc
    33001 taagacagct gaaggctcac aaaggtggct tatgttgctg gcggtgctta tgctaattgt
    33061 tatgattaac aagctgtcaa aggataggct agagcctgct gtaccagtct atcaggcctt
    33121 gctgtcagct actaaatgaa tgagtcagaa aaaggtgcta tgtaggtgcc tttttctgcg
    33181 ttttgcttta ggctgatagt gagcttgctt gaagtcaaga ctggcttcat gcaggcttca
    33241 gagtctttgc taggaatgct ataaggtggg ttctgagctt atctatttag gatatgtgac
    33301 aaatgctgtt aaaatatgtt acactaacat tagctttaat ttcaatagaa agtatctgat
    33361 ataggttatg aattatcatt ttgatgcctc taagttaaag ttgggcatgc gtacgtttaa
    33421 aactggctta gctgtgtttt ttgttttgct tttgtttcat ttttttgatt ttcagggcct
    33481 gcagataggg gccttgacag ctgtttttag cttgagagag agctttgata agacgatctc
    33541 ctttggcacc tctcgtattt taggaaattc gattggtggt ttttttgcga ttatatttta
    33601 cctgcttgat actctttttc agagcgcatt ttgggttacc ttggtttttg ttccgatatt
    33661 gacgatgcta accattatgt ttaatgtggc ttttaataat caatctggca tcatcggtgc
    33721 agttgctgct cttttaatta tcaccttgtc tattcctact ggcgaagctt ttatgtatgt
    33781 tattgctcgg gtttttgaaa ccttttgtgg ggtttttatt gccattcttg tcaatacaga
    33841 cgtggagctg attagaaata agtggttgag caggaagctc aaaaaatgat gtcaggaaat
    33901 ataacatgtg accttgacag tttattaaaa tcaacctata ataggggtgt gaaaggaagt
    33961 tttcatgaaa gaaaaagaac tcagacgctc aatggcagtc tttccgatcg gtgcagttat
    34021 gaccttgaca gatctatctg ctcggcaaat tcgctattat gaggaccagg agctgataaa
    34081 gcctgagaga acagagggca accggcgctt gttttcctta aacgatatgg atagacttct
    34141 tgaaatcaag gactttttga acgaaggatt aaatattgcg gcaattaagc gagaatatgc
    34201 tgaacgccag gataaattaa tgcaaaagca aaaggtattg actgatgcag atgtgagacg
    34261 gatcttacat gatgagcttc ttaatcaagg tggcttttcc accccttcac agcatattgg
    34321 gaattttcgt atctagcata cgactggcat gaaagaaaaa ggagattgat taatggcaat
    34381 cacagcagct gatgttcgtc gcgaggtcaa agaaaagcat gtgacctttc ttcggttgat
    34441 gtttacggac attatgggtg ttatgaaaaa cgttgagata cctgcaactg aggagcaatt
    34501 agataaagtc ctatctaata aggtcatgtt tgatggctcc tcgattgaag gctttgtgcg
    34561 tatcaatgaa tcagatatgt atctctatcc tgatttagac acttggatcg tctttccttg
    34621 gggagatgaa aatggagctg ttggtggctt gatttgtgat atttacactg ctgaaggcaa
    34681 gccctttgct ggtgacccac gtggcaacct aaaaagagcc ttgaagcata tggatgaggt
    34741 tggctatcag tcctttaacc ttggtccaga gccagaattt ttcttgttta agatagatga
    34801 agctggagag ccaacgcttg aggtcaatga caagggaggc tattttgacc tcgctccgat
    34861 tgatctggca gacaataccc gtcgtgaaat tgttaatgtc ttgaccaaaa tgggctttga
    34921 ggtcgaagcc agccaccatg aggtagctgt cggtcagcat gaaattgact ttaaatatgc
    34981 agatgccttg aaggcctgtg ataatattca gatctttaag cttgtggtca aaaccattgc
    35041 gcgtgagcac gggctctacg ccacctttat ggcaaagccg aaatttggta ttgccggctc
    35101 aggtatgcac tgtaacatgt ccttgtttga caaggagggc aacaatgcct tttacgatga
    35161 aaatgataag cgtggcatga agctatcaga tgatgcttat tatttcttag gtgggttgat
    35221 gaagcatgct tacaattaca ccgctatcac aaatccaacg gttaattcct acaagcgctt
    35281 ggttcctggt tatgaggctc ctgtttatgt tgcttgggca ggaagcaatc gttcacctct
    35341 tattcgtgtt cctgcttctc gtggtatggg gactcgttta gaattgcgtt cggttgatcc
    35401 aacagccaat ccttatttag cacttgccgt tttactagag gcaggcttag atggtatcat
    35461 taataaaatt gaagcgccgg caccgattga ggctaatatt tacatgatga cagcagagga
    35521 gcgcaatgct gctggcattg ttgatttacc gtcaacactc cataatgctc taaaggcgct
    35581 tcaaaaggat gaggtcattc aaaaggcttt aggtgatcat atttacacca actttttaga
    35641 ggcaaaacgg attgaatggt cttcctatgc gacctttgtt tcgcaatggg agattgataa
    35701 ttacttacac aactattaga aaatcaaaac tcgctcagct ttttgagtga gttttttatg
    35761 cttttattca gcagatatgg ttatttatac ttatcattat ttttgtacgt tataatgaca
    35821 gaaatggcaa ggtcgtctgt ttataaaaat aaaatcaaaa attttcagat aaatctattt
    35881 ccttttttca gaattatggt ataatctaat ttaattattt taaataacta ttttgttagg
    35941 aggaaggtta tatgacagta ctaggaacaa aagcatgtaa gcgtctgggc ttagcggcag
    36001 ttacgctagc ctctgttgct gccttgatgg cttgtggaaa taagcaatca gcgtcaacag
    36061 acaaaaagag tgagattaat tggtatacgc caactgagat catcacactt gatatctcaa
    36121 aaaatacaga tacctattct gctttggcta ttggtaattc tggcagtaac cttttgcgtg
    36181 ttgatgctaa ggggaaatta cagcctgatt tagctgaaaa ggttgatgtg tcagaggacg
    36241 gcttgaccta tacagcaacc ctgcgagacg gcttgaaatg gtctgatggt agtgatctaa
    36301 ctgcagagga ctttgtgtac agctggcagc gaatggtcga tcctaagaca gcctcagagt
    36361 acgcttactt ggcaactgag tcacatctga aaaacgcaga ggacattaat agcgggaaaa
    36421 atcctgatct agactctcta ggggtaaagg ctgatgggaa taaggttatt tttaccttaa
    36481 cggagccagc accacaattt aagagcttgc tgtccttctc taactttgtt cctcaaaaag
    36541 aatcctttgt caaggacgct ggcaaggact atgggacaac atcagaaaag caaatttact
    36601 ctggtcctta tattgtcaag ggctggaatg gcactagcgg aacctttaag ctagtaaaaa
    36661 ataaaaacta ttgggacgcc aaaaacgtca aaactgagac agttaatgtt caaacggtta
    36721 aaaagccaga tacagctgtt caactataca agcaaggtaa gctagacttt gcgaatattt
    36781 ctggtacgtc agctatttac aatgctaaca aaaagcataa ggacgttgtt ccagttcttg
    36841 aggcaacaac agcctatatc gtgtataacc agacaggagc tattgaaggg ttgaatagtc
    36901 ttaaaattcg tcaagccttg aatttggcaa cagaccgtaa gggaattgta tctgcggctg
    36961 ttgatacagg atcaaagccg gctacagcgc ttgttcctac aggtcttgct aaattgtctg
    37021 acggaacaga tctaacagag catgtagcac ctggctataa atacgatgac aaggaagctg
    37081 caaagctctt caaggaaggc ttggcagagc tgggcaagga tgccttgaca atcaccatca
    37141 cagctgatgc tgatgcgccg gctgccaagt ctgcagtgga ttacatcaag gaaacctggg
    37201 aaacagctct tcctggcttg accgttgaag agaaatttgt tcctttcaag caacgtcttg
    37261 aggatactaa aaaccaaaac tttgaggttg cagttgttct ttggggtggt gattatccag
    37321 aagggtctac cttctatggc ttgtttaaat cagggtctgc ttataactat ggcaaattta
    37381 cgaatgcaga ctatgatgcg gcctacaaca aggctctaac aacagatgcc ttgaatacag
    37441 atgcggctgc tgatgattat aaggcgacag aaaaagccct ttatgacaat gctctttaca
    37501 atccccttta cttccgtagt ggtgagggct tgcaaaatcc aagcatcaaa ggtcttatcc
    37561 gtaattcaac tggtctaaat gttgacttta cttacgctta taaggaataa caataatatt
    37621 atcgtaagct tatactgacc tagcaaggac agctccttgg tgggaagtgt ttaagagaag
    37681 cttagggcta gctaggagcg tctatcctat aagccttggc aagcatattg caagaattgg
    37741 tcttaaccag ttcttgcttt tggttagagg aaaaatatga ttaaatatct tttaaagcga
    37801 gtggctattt tagtagtgac actctgggtg gtgattaccc tgtccttctt tttgatgcag
    37861 gtgatgcctg gaacacccta taacaatcct aaattaactg atgacatgat tgctatgctg
    37921 aatcagcagt acggcttaga taagcctctt tggcagcaat atttgaagta tttgtttgat
    37981 attcttcatg gtgactttgg caccagctat cagtcgatta accaatcagt gacaaccctg
    38041 atctcgcagc gtctgggggt atctgtacac ttaggggtac aggcgcttat tgttggtatt
    38101 agctctggct tagttgttgg tgctgtctca gcgcggaata aaaataatag cattgatgcc
    38161 attttaagtg ttatctcaac gcttggtatt tctatgccgt cctttatcat tggtttgctg
    38221 ctgttggatt atttgggctt taaatggaat ttgcttccct tgtctggctg gggaagcttt
    38281 ggacaaacga ttttaccgac gcttgcttta gctattccag tctttgctca ggtgacccgt
    38341 tttttccgca gcgagatgat cgagacctta tcgacagatt atattcagct agctagagct
    38401 aagggcttga ccaagcgtca ggtgacgcgt cggcatgctt accgcaattc gatgattcct
    38461 gtgttaacct tggttggtcc gatggctgct ggtattttga cgggatcagc cctgattgag
    38521 cagatttttt ccattccggg gattgggcag cagtttgtga cctctattcc caccaaggat
    38581 tacccggtga ttatgggaac aacgattgtc tatgcgctaa tgctgatggt tgctattttg
    38641 gtaactgata tgatcattag tatcgcagat ccacgtgttc gtttgggata ggagagtgct
    38701 atgctagaag aaacaaaatc atttaagctt gttggagcag ggagcttagc gacacaagaa
    38761 aaaattgaaa agccggcgct ttcctttctt caggacgctt ggcgtaggct aaagcacaat
    38821 aaactagctg ttatagcgat ggggttttta gctgtgctgc ttttgttttc tattggttct
    38881 ttatttgttg tgtctacaga tgatgccaat agctttaaca gtaaggaggt aagcatatac
    38941 cgtaacctgc cgccaaagct aagcagcagc ttgccatttt ggaatgggac cattacctac
    39001 gctggtaata cagagcccaa tgatgcttat gtggatcaag gggtcccaga ggacaaggcc
    39061 ttcttactcg ggacggataa tctggggcgc agtattggaa aacgtattac agtagggatt
    39121 cgaatttctc ttttgattgc tattgtcgca accctgattg atctagtgat tggggtaacc
    39181 tatggcttgg tctcaggctt tgttggtggc aagactgaca tggtgatgca gcggatcatt
    39241 gagattatct cctctattcc aaatcttgtt attgtgacga tgcttgggct tttgcttggc
    39301 aatggtgtga cttcaattat tatttcaatt gcgattgtag gctggacctc aatggctagg
    39361 caggtccgca acttaaccct gtcttatcga gagcgtgatt tcgtccttgc ttctcgtgcc
    39421 ttgggagaaa gtaatatcag gattgccttt aagcatgtat tgccaaatat ttcagggatt
    39481 atcattgttc aaatcatgat gactgttccg agtgctatca tgtatgagtc agttttatct
    39541 gcgattaatt taggcgttaa gccaccgaca gcttcgcttg gttcattgat tactgatgca
    39601 caagaaaacc tgcaatatta tccttatcag gtgctgctgc cggcttttgc cttggtgcta
    39661 atttcgttgg cctttattct gttgggtgat ggcctacgtg acgcttttga cccaaaatca
    39721 agtgatgagt agaggggaga taaaatgacg aatgaaacca ttttaagtgt caaaaacctc
    39781 catgttgatt ttaaaaccta tgctggagat gttaaggcga ttcgtaatat cagctttgag
    39841 ctaaaaaagg gagagactct tgctattgtg ggagaatcag gctcagggaa atctgtaacc
    39901 actcgcaccc tgatggggtt gaatgctaag aatgcaagca tttctggaga catttgcttc
    39961 aagggcaagc agctcaatga gctgaaggag gaggaatggg tgaaggtgcg tggcaatgaa
    40021 attgcgatga tcttccagga tccgatgacc agccttgatc ctaccatgac aattggcatg
    40081 cagattgcag aggcaataat gattcatcaa agtattcata agacagaagc cttgaagcgt
    40141 gctttagacc tgatgcgtca ggttggtatt ccaaatgctg aggagcacct taaggattac
    40201 ccacatcagt ggtctggggg catgcggcaa cgggctgtta ttgccattgc tctagctgcc
    40261 aatcctgata ttttgattgc agatgagccg acaacagctc ttgatgttac cattcaggcc
    40321 cagattttga agctgatgaa ggatattcag tctcagaccg catcatcgat tatctttatt
    40381 acgcatgacc ttggtgttgt tgctggaatg gcagatcgcg ttgctgtcat gtatgctgga
    40441 aaaattgttg aatatggaac ggttgatgag gtattttacc acccgcagca cccttatacc
    40501 tggggattgc tcaattcgat gcctacaaca gctactgcag caggtagctt gaggtctatt
    40561 cccggaacgc cgccagattt attaaaccct ccaaagggtg atgcatttgc tgcccggaat
    40621 gagtttgccc tagacattga ccatatcaaa gagcctccaa tgttcaaggt aagtgacagc
    40681 cactacgcag caacctggtt gctagatgag cgtgctccta aaataacccc tccattccca
    40741 atccgcaagc gttgggcaaa atggcaggaa atggaagaga ggaaggctta atgacagaag
    40801 ctcgtaaaaa attaatcgaa gtaaagaatg tttccttaac ctttaacaag gggaagaaaa
    40861 acgaggttaa ggctattgat cgccttagct ttgacattta tgagggggaa gtatttggcc
    40921 ttgttgggga atcaggctca ggcaagacga cagttggtcg agctattttg aaattgtatg
    40981 atattagtga tggcgagatt atctttaatg gagaaaacgt ctcccaatta aaggggaaaa
    41041 agctgcatag ctttcgtaag catgcgcaaa tgatcttcca agatcctcag gctagtctga
    41101 acggtcgcat gaaaatcaga gacattgttg cagagggctt agacattcat ggcttgacag
    41161 cctcaaaggc agagcgtgag gcaagagtcc aagagctgtt aaagcttgtt gggcttaatc
    41221 aggatcattt gacgcggtac ccacatgaat tttctggtgg ccaacgccag cggattggca
    41281 ttgcgcgtgc cctggctgtg aagccgacct ttattatcgc agatgagccg atttcagcgc
    41341 ttgatgtgtc gattcaagca caggtagtga gtctcatgca gcaattgcaa aaaaagcgtg
    41401 gcttgaccta tctctttatc gctcacgatt tgtctatggt caaatacatt tcagaccgta
    41461 ttggtgtgat gcattggggc aaaatgcttg agattgggac atctgatgag gtttacaatc
    41521 acccgattca cccttatacg aaaagcttga tctcggccat tcctgagccg gatcctgaaa
    41581 aggagcgtag gcgcattgca gaggtttatg atcctagtca agagctagat ggccaagagc
    41641 ggcaaatgca tgaaatcact cctgggcatt ttgtcttagc gacgcaggcc gaagccgatc
    41701 agtaccgagc agagcgtgac ctctaaggca ttagcataac agtagtctgc taaaaagctg
    41761 atgtgatctg gtctttttag acttgaccga ccaaaagttg tatggtcttt gccgatcaaa
    41821 agcaggtgcc atgcgatttt gttggtatgg tggggctttg tcagccaacc tagactgcac
    41881 aaaaagctcc ttatgataga atttgtagca tgaggctggg acgcaagtct atcctaaaat
    41941 aaaccaaaat aaaacaaccg aacaggtctg gcttttgaaa tttcagaaag ctagacctgt
    42001 tcggttttta atgaatgaga ttaggtcata aagtatctta gttaagattg tctaaagtgc
    42061 agctcttttt gaggtgtggt ttgacaggtt tgctaagctc agcaggctat ttttagtagt
    42121 atagctagac aaaggccctt aagctagctc agcacgtcac tctgttaacc ttagctaaca
    42181 gcacgtgttg ggcaagtagt atgcctcaag ccttgtacat cagtcattga cgttgacgca
    42241 acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca ggcgttagaa
    42301 ccatcggaat gataataggc tcgcgctctg ttttttcgta aaggaaggga cgaagcgcat
    42361 taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga gcgatacgaa
    42421 tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg cgcatgtaga
    42481 taaagccgcg gctgagaata tctggtcctg ctaagatcat ctgtgtctca aaatcaacag
    42541 tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga aggactgctg
    42601 tcccaatatc gccaatgcca ttgccatcta cataaatgtc ctgagcattg aaatgaccgg
    42661 ctatacgagc gctatcgctg gtcaaggcca atacgtcacc attttccatg ataaagatat
    42721 tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc atacggtatt
    42781 caccatggac aggcataaag tattttggct taataaggct aagcattagc ttttgctcct
    42841 gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata acgtcaactc
    42901 cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca ggaattggac
    42961 ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg gtaccattgg
    43021 caatcctagc aagggcggcc atcgactctc cctgactgcc ggtacacatg atcaaaatct
    43081 cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt gggaccttga
    43141 tgtagccaag ctcgataccg ttaacaatag ccttttccat cgaacggcca aatacagcaa
    43201 ttttacgccc cgtcttaaca gcagcctctg cagcctgctg caagcggtag atatttgaag
    43261 caaaggaagc aaaaatgata cgtccatgaa tgccttcgat aatattcatg attgactggc
    43321 caacgacctt ttcagaattc gtaaaggttg gtatctcggc attggtcgaa tctgacaaca
    43381 ggcaaagaac cccgtcctta ccaagagcag ccatgcgatg taggtcagcc ggatcaccaa
    43441 caggcgtaaa gtcaaacttg aagtcaccag tacagatgac cttcccttgt ggggtgtgga
    43501 taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaagta acgctcatat
    43561 gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcgtcg cgtaagagac
    43621 catgctcctc cagctttcct cggataagag ctagggctaa ggggcctgca tatataggca
    43681 cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcgtga ccatgagtaa
    43741 tcacaagggc cttgacgcgc tccaaattgt caacaatata agagtaatcg gggatcacat
    43801 agtcaatccc tagcagatcg tcctctggga atttgatgcc ggcatcaaca atgatgattt
    43861 catcttggta ctcaataccg taggtgtttt tgccgatctc tcccagacca ccaatcgcat
    43921 aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc cgttaattca
    43981 aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc gatgaattcg
    44041 acattgtaat cggtgtactc ttcaaccatc ttgcgggctt tgatacgccc ctcaagctca
    44101 cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg actgcgttcc
    44161 tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc atgatgaatc
    44221 gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg acgattacct
    44281 atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact aagattatac
    44341 catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc ggtgatgaga
    44401 ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgaa atagaaatga
    44461 cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag gcattatctg
    44521 ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt aagaagaatc
    44581 acagcattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac ctgaagccaa
    44641 aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc ttgcgtgttg
    44701 ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt ggcgtatcaa
    44761 gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg gttgtccctt
    44821 tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa aaagctgtga
    44881 aacaggataa gtacgcgtcc tttgatgctg ttttagcaga tctggtctct tgtgaccatg
    44941 tgatttttgt tggagaggtg gagggctttg cagaggatat tcgatcagcc ttgccagagg
    45001 ccaagataaa gccaagtttg ccatcggctt ttgaggttgg tttgctaggc agcagccttt
    45061 cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag gcagaggaaa
    45121 actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga gtttagcgat
    45181 gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg tctatggtca
    45241 atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg ttgattattt
    45301 taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc tgccaggaga
    45361 aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga ttgcctcttg
    45421 gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta gagcgtcaaa
    45481 ccgtagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc agcgtagcaa
    45541 ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa agaatgacag
    45601 atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct atcttaaaaa
    45661 acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac aagcgttttg
    45721 gtggagtggt tcctgaggta gctagtcgcc atcatgtgga ggtgattacg acttgctttg
    45781 atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt gcggttacct
    45841 atggcccagg tctggtgggg gccttgctag tcggcctagc agcagccaag gcctttgctt
    45901 gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg atggcggcac
    45961 gcgagcaagg agagctggaa taccctctta tggccctctt ggtttccggt gggcatacag
    46021 agcttgtcta tgtgacagag ccgggagagt atcatattgt cggagaaaca cgtgatgacg
    46081 cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat cctgctggtc
    46141 gtgagattga tcagctagct caccaaggga cagataccta tcattttcct cgtgccatga
    46201 tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt atcaacctgc
    46261 accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctttgt gcgtcctttc
    46321 aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag cagtacccat
    46381 caaaaatgct agtcgttgca ggtggagtag cagccaatca ggggcttcgt gagcgtttag
    46441 ccaaggaaat caaggactta gatgtggtta tgcctccttt aagattgtgt ggggataatg
    46501 ctggtatgat tgccttagca gcagctgttg agtacgataa agggcatgta gcaggcttgg
    46561 acttaaatgc taagccaagt ctagcttttg agagctttca tcagcagtag cattggtatg
    46621 aggagattgt catgttttat ttattgcttc ttccattgat ttgtagcgtg gtgtttttgg
    46681 ctgtttatgt taaggagcca agaaccctgt ggctaggagc cagctttgta gcaacactag
    46741 gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaaaacagg cttcagggtg
    46801 ttggtatcct agtgctaggt gtcattggct ttcttgcgat tgtatggttg atgtcaagtc
    46861 cctttatact cttgctcttt ctaagcttta atggcattag gctcatcaaa agagaaggac
    46921 tttccttgcg aaatttattg ctgattggct cagcggtctt gttgtttgtg caccctttta
    46981 ttagcagact attgttagag agtatcggtg actcaaagct tttaaggatc atgtatgaga
    47041 ctagtgattt gttaatcctt tacctcttgt tgatcgtatc agcctacacc atctcaagca
    47101 tactgaatac cttttacctc agaaaaacca aggaagatta tattattgtg ctggggagcg
    47161 gtctaaatgg agaccaggtc acccccttgc tagccagccg tattaataag ggcattcagg
    47221 tttaccggaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg gctgatgagc
    47281 taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc aaaagtgaag
    47341 atatattagt tgaaaaccaa tccagaaaca ccagagaaaa catcctgttt tctaagcaat
    47401 taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg tttagagcct
    47461 tattactggc taaggagcta gccttgcctt gcaggggcta tggggcaaaa acaaagctct
    47521 actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta aagaaaaagc
    47581 agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga gtggtgatga
    47641 tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca cctcgtcttg
    47701 ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca gcctttttaa
    47761 aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga tgttcaatgg
    47821 aaccaatcac tattgttaca gcaaaaagca ggcctttagg aacgtttgct ttgctggtaa
    47881 gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt gatttagctt
    47941 gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc ataccgagct
    48001 atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc aagcttacca
    48061 gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa aattgatacg
    48121 gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat cacgattttt
    48181 caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat caccctttgc
    48241 tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct tatggtattt
    48301 agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata atctcagagc
    48361 gttatcagcg ccctgaattt cctcaaccgg tcattaaccg gttaaggaaa catagtctta
    48421 ttatacacca atttcagcca aatgcaagaa aaagatgccc tgattaaggg gataatgaca
    48481 aataagccta tcagtcaatc agctgataag cttatcttaa tcaatgtggg cttcctgcca
    48541 cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca ttaatatcta
    48601 agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc ttagggttga
    48661 tttcttttaa gtcaatgccg cccttggtta caaaggactt ggccagagac atttttcctg
    48721 tgattggaat cggtaattgc ttaatcttgt tgacgagctc ctgggtctgt gtgggagtaa
    48781 gctgctttcc tttttccgga tagccctttg ttaaaaagtc agcgactcgc tcaggcatca
    48841 aagccttgag cgcattttta agggcttttt cccggtgctg cgctaaatag ctgagcagct
    48901 cagctgcgga ggtttgcggc agcaggtcaa gctctgctat gtcacctccc ttaacaaagg
    48961 aagaaagcct tagagcagca ggacctgaca gcccaaaatg ggtaaaaagc aaatcgtggg
    49021 tgatctgatg cttcccatag ctaagggtca catcatcaag ggaaatcccc tgtaaggcct
    49081 tatgtggaaa gtctgttaat aagggacttt cggcagcctc tagctcggtg acagctatgt
    49141 tgaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatgga taggatttgc
    49201 ctcctgttgc cacgataagt ttctcgcagc tgaaggtctg atcagctgat ttgaggtaaa
    49261 aaaggttgtc tcgctttttg accgagacaa tctcggtact ggtcagcacc tgagctccca
    49321 gtgacttgat tttttgctcc agcgcattaa taatcgtctt tgattgatcg gtcgcaggaa
    49381 acatgcgtcc atgatcctct tctttgaggg gcacgccgtt ttctctaaaa aaggcaatga
    49441 tgtcataatt atcaaattgg gaaaagacgc tatagagaaa gcggccgtta cctggaatgc
    49501 cagcgattag ctcatcaagg cttccgctgt tggtgacatt gcagcgtcct cctccagtcc
    49561 cagctagctt tttgcctagg cgtctgtttt tgtcaagcag gagtgtcttg tagccatagt
    49621 agctgctaga gatggctgcc atcataccag caggcccacc tccaataata atcgtatcgt
    49681 atgctatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat gtaaactagg
    49741 ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt cagttacagt
    49801 aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga cattttggga
    49861 gtgagccgtc aggctgtcaa taatcgtgtc aagtccttac cagaggagga ccttgataaa
    49921 aatgataaag gagtcactgt cgttaagcgt agtggcttag ttaagctaga ggaaatctac
    49981 aagaaaacga tttttgatga tgagccaatt agtgaagaga ccaagcagcg tgagctctta
    50041 gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca gctaaaggca
    50101 aaggatagcc agctagctgc taaggacgag cagatgcgta ttaaggatgt tcagattgcc
    50161 gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat ggcagacaaa
    50221 gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt acgactgcaa
    50281 gcagaagaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg tttatttggt
    50341 aaataacagc ataccaagac cctctaaggg tcttttttga ggagataaga atgaaacaat
    50401 tagaagctta tattgccttt gatatggaat ttaatactgt caatgaggtt agtcatatca
    50461 ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt gacagctatg
    50521 tttacactgc tgttcccctg caaagcttta ttaatggctt aacaggcatt acctcagata
    50581 agattgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa tttgtcggtg
    50641 acacgccttt gataggttat aatgcacaaa agtctgattt gcctatttta gcagcaaatg
    50701 gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat gagagacgaa
    50761 gtagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat tttttaggga
    50821 taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt gtctatgaag
    50881 cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa gcgattacag
    50941 ataacccctt tgcagctcta ggagggcttt ttgactagta gcgctagtca tttctctgaa
    51001 aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt ctataatgag
    51061 gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct agcaaaagca
    51121 gcaggtgtca ctgtcaggac agtgcaatat tacgataaca gaaacctcct atccccatct
    51181 gctatcacag acggaggaag acgccagtac acaagtgctg acttgagcca gctcaagcgt
    51241 atcctctttc ttcgagagct ggatttttca atcgagagga tcaaaaggat ctttgccgag
    51301 gataatacag accaggtctt agagcttttg cttcaggaac acatcaggca gctaagagca
    51361 gaagctgctg ataaaaaggc taagcttgac agggctgtca agcttctaaa agaggttgaa
    51421 aaggacgctt gtcaatcact tgacgatctt tcagaccttg ccttgaggat agaaaatcaa
    51481 gaaagctggc gtcagctcca gcgcaggacc tggccacaac tcattttggc aatcataagc
    51541 tatgttctag tcatggtatt agctgcttgg cttcgtcaga tctggttgat ctggcttgga
    51601 atgtcactgt ttatcttggc agtgaatggt cttgtttggc attacaaaaa gcaggtgccc
    51661 tacctttgtc ccaactgtca caagatcttt gagcctacct ataaagtctt tagcttggca
    51721 ggacacactc caaaaaccag aagattacgc tgtcctcatt gtcagcaaaa atcttactgc
    51781 cttgaattgg ctaaggaaaa ataattaaaa atctccgctg gatacccagt ggagatttct
    51841 tgctattaaa atggtagctt gccggcaaag gcacccaagc ttttcttggt tgcctcatca
    51901 atttgagtaa gggcgtcatt gatggcttga gtggtcatgt cttgaagcgt ttcgatatcc
    51961 tctggatcca caacagcctc cttaaaggtg atattgacca ggcgtttgtc accagtaaag
    52021 gttgctgtta ccagttcttg ggcagatttg cctgaaaatg aggtagcagc tagatcagcc
    52081 tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt ctgcatattc
    52141 atcatagtta tataatctcc tttattatca agtgttttga gtgtttcggt tgctcatttt
    52201 agtgctttat ggggcagttt tttatatttt atcaagagca tttagttttt gcaatagctc
    52261 ttttctcatt tttgcggtag tatgagtgta gattttgatt gtcgtattga catcagcatg
    52321 tcctactcga tccagatggc ttttaatggg ttaataaagt gatatgagca tggcggaagg
    52381 tgtagctaat tacagtaaag ccataaggtt tttctgtagc tttttttaat ttgtcttgag
    52441 aataaataat tgattaagta tgatcaacag ttcgacatta atgttgtcac ctacactgca
    52501 actaaaaaac tgatatagaa ggtagagccc caagataaga taaaatcctt aacgatgctg
    52561 atggtgattt tttgagtaat tttcaattaa ctaagtaaac atcaatgtga cttatttgat
    52621 tagattcaaa ttttgtatta tatctatatt cagggatagt aaataaattt gtttcttttg
    52681 ttttatctgc atatt
//
LOCUS       DARYSY010000009        52030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYSY010000009 DARYSY010000000
VERSION     DARYSY010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52030
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(421..780)
                     /gene="rplT"
                     /locus_tag="TVR04_000433"
     CDS             complement(421..780)
                     /gene="rplT"
                     /locus_tag="TVR04_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1269148.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(840..1037)
                     /gene="rpmI"
                     /locus_tag="TVR04_000434"
     CDS             complement(840..1037)
                     /gene="rpmI"
                     /locus_tag="TVR04_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1269149.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(1077..1607)
                     /gene="infC"
                     /locus_tag="TVR04_000435"
     CDS             complement(1077..1607)
                     /gene="infC"
                     /locus_tag="TVR04_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1269150.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1622..1744)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1768..2448)
                     /locus_tag="TVR04_000436"
     CDS             complement(1768..2448)
                     /locus_tag="TVR04_000436"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1269151.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAERPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVKQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIATDFDTLKTEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2463..2972)
                     /locus_tag="TVR04_000437"
     CDS             complement(2463..2972)
                     /locus_tag="TVR04_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1269152.1"
                     /translation="MAKEPWEEKIVDDNKTTRTRRSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKETAKKTSSKSKAKTKAKPKVSSSTSAAS
                     DTTSPSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYA
                     NPGDEVNIK"
     gene            3021..3218
                     /locus_tag="TVR04_000438"
     CDS             3021..3218
                     /locus_tag="TVR04_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1269153.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3205..3693)
                     /locus_tag="TVR04_000439"
     CDS             complement(3205..3693)
                     /locus_tag="TVR04_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1269154.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAVLVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3738..4961)
                     /gene="pepT"
                     /locus_tag="TVR04_000440"
     CDS             complement(3738..4961)
                     /gene="pepT"
                     /locus_tag="TVR04_000440"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1269155.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5131..6150)
                     /gene="galE"
                     /locus_tag="TVR04_000441"
     CDS             complement(5131..6150)
                     /gene="galE"
                     /locus_tag="TVR04_000441"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1269156.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVIDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKNIIFSSSATVYGDPHTIPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6218..8587)
                     /locus_tag="TVR04_000442"
     CDS             complement(6218..8587)
                     /locus_tag="TVR04_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEL1269157.1"
                     /translation="MLDMLLFSLSSLYLSIVAVSKNTLNKGAYGSWLVLVLVAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALISL
                     LILGVLLKKYLFKKDNQSSRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSS
                     LVSLNLFKYSFCSYMLMFVVYYLIVTAFIGVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFALVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQLISIIFILVLSGLLIYILYKSYFRER
                     ILPTLYLRLTSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIPEIHHIMEITTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKYSPAISNAFSPKDRIALHLASANNYSRKIVYNKLGFE
                     TFIATEDSADKPKHLVRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDGSETDSLKSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEIKYLTDYFIWSNHQANKLARPRVNSSDFTSLLLEHTNSKVSPYYALL
                     TDVLDTRNSDDSQLTATQKQVASDLKLLEYDLIEGKGYINAYPDFFNMK"
     gene            complement(8667..9830)
                     /locus_tag="TVR04_000443"
     CDS             complement(8667..9830)
                     /locus_tag="TVR04_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1269158.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKALPSIVIEHGGGYVQVGENVKGHQLLDLFAKLYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYESFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLTSLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCNLQEAIHQQVLSGFTWEVTVRQLVAEVITSESESNV"
     gene            complement(9844..11328)
                     /locus_tag="TVR04_000444"
     CDS             complement(9844..11328)
                     /locus_tag="TVR04_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1269159.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLVIL
                     VAIAALLIIFLPSNIEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSRLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     AIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRHPIVYGFMLLRHMFAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPALSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILAMITRTMLQYYT"
     gene            complement(11332..12573)
                     /locus_tag="TVR04_000445"
     CDS             complement(11332..12573)
                     /locus_tag="TVR04_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1269160.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQVRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICFISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFVQLEHRLSLVLLLASLAILVASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARGFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12557..12913)
                     /locus_tag="TVR04_000446"
     CDS             complement(12557..12913)
                     /locus_tag="TVR04_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1269161.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12918..13607)
                     /locus_tag="TVR04_000447"
     CDS             complement(12918..13607)
                     /locus_tag="TVR04_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1269162.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSIKAGADCVIGSRFVSAEKNRSLRMMGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13637..15382)
                     /locus_tag="TVR04_000448"
     CDS             complement(13637..15382)
                     /locus_tag="TVR04_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1269163.1"
                     /translation="MKRILLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMEPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTSYPASLIVDHMSQVHLPDAKYLLAHKYLPNQ
                     PISIAPSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKGILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKN
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLPQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15379..16386)
                     /locus_tag="TVR04_000449"
     CDS             complement(15379..16386)
                     /locus_tag="TVR04_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1269164.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     HSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQGNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEAELMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRLTDNSDSR
                     PVAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHEL
                     RQTLVDQEALQAERIDQLEQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16407..17615)
                     /locus_tag="TVR04_000450"
     CDS             complement(16407..17615)
                     /locus_tag="TVR04_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269165.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNDEQGAVAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSQLNDIKLKLEVTVRDQNGQMLLFSTADHSPLIVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17615..18418)
                     /locus_tag="TVR04_000451"
     CDS             complement(17615..18418)
                     /locus_tag="TVR04_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269166.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFAELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18418..19353)
                     /locus_tag="TVR04_000452"
     CDS             complement(18418..19353)
                     /locus_tag="TVR04_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1269167.1"
                     /translation="MKINILMSTYNGERFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRIRLINADVQENLGVIQSFYTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKVSEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMITHALAKQWLSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLKPTDRRLIEAYVGLLDKPFYQ
                     RLSDLKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19343..20497)
                     /locus_tag="TVR04_000453"
     CDS             complement(19343..20497)
                     /locus_tag="TVR04_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1269168.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKTYPWAKTTFIAYGTETERSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFIGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20622..21470)
                     /gene="rfbD"
                     /locus_tag="TVR04_000454"
     CDS             complement(20622..21470)
                     /gene="rfbD"
                     /locus_tag="TVR04_000454"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1269169.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGKKPAGQEWLETDTPDPQTEYGRAKRLGEQAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCYLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21611..21949)
                     /locus_tag="TVR04_000455"
     CDS             complement(21611..21949)
                     /locus_tag="TVR04_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1269170.1"
                     /translation="MTETPKYTEEQVAAIKDRILEALETVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22301..23410)
                     /gene="rpoD"
                     /locus_tag="TVR04_000456"
     CDS             complement(22301..23410)
                     /gene="rpoD"
                     /locus_tag="TVR04_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1269171.1"
                     /translation="MAKEKEVTTFNVQVAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23419..25230)
                     /gene="dnaG"
                     /locus_tag="TVR04_000457"
     CDS             complement(23419..25230)
                     /gene="dnaG"
                     /locus_tag="TVR04_000457"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1269172.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTIAPSQASLGQKQHSHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEHFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAVYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNAIASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFCFDTPALQ
                     TLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSKQMTLLKQ
                     RELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25477..25851
                     /gene="mscL"
                     /locus_tag="TVR04_000458"
     CDS             25477..25851
                     /gene="mscL"
                     /locus_tag="TVR04_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1269173.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(26076..26252)
                     /locus_tag="TVR04_000459"
     CDS             complement(26076..26252)
                     /locus_tag="TVR04_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1269174.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26418..27230)
                     /locus_tag="TVR04_000460"
     CDS             complement(26418..27230)
                     /locus_tag="TVR04_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1269175.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQENGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKAD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLAGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27298..28413)
                     /locus_tag="TVR04_000461"
     CDS             complement(27298..28413)
                     /locus_tag="TVR04_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1269176.1"
                     /translation="MKLPAFGVEEWLNQHEKSAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKLYLEELINIAREHDIYLLSDEVYHSFASDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEAKASYIKPSEVSTAFVRLDIDEDIEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLNRLSQCLKNIQ"
     gene            complement(28682..32323)
                     /gene="addA"
                     /locus_tag="TVR04_000462"
     CDS             complement(28682..32323)
                     /gene="addA"
                     /locus_tag="TVR04_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1269177.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDRLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFADIPDQAVDILLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVGFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEAQKQLHPENRAQLLLYNTDQAQEGTEEASTNDGISAGEVTLVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     TNLYALAIRADQFEQSGYKGLSRFIGMIDKVLEMQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFALADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIVATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKSFDLPDFSKKKAVEPSQIGSSLHELMQRIPMSDQVTAGDIEQALQFVSAD
                     AEVKARIDIKKVTSFFATTELGQLLQEHHQCLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDHYQHSAELKQRYQQQMDLYAEALSQSYGIAKVEKYLVLMGG
                     PQLEVVRLA"
     gene            complement(32313..35534)
                     /gene="rexB"
                     /locus_tag="TVR04_000463"
     CDS             complement(32313..35534)
                     /gene="rexB"
                     /locus_tag="TVR04_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1269178.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEELLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSQLDWQLSAKDKSRVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLTFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRREADREKDEEVWKTFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNSATQ
                     ELVLSLPTSSTNGSDDVSPYLKELIALGVSVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADEMTDEDRNFWTVALRYLKRRLANEQLSLPAPEHHLVTKPVAPEVIETRFP
                     SHQPLSLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     TDAAFDKKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGMQV
                     AKQEEAFELALGHQALIRGVIDRIDQLADGRLGIVDYKSSARVFDIGAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35745..37145)
                     /locus_tag="TVR04_000464"
     CDS             complement(35745..37145)
                     /locus_tag="TVR04_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1269179.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGAIHLYERRQ
                     QVPLGDDVSLPPVSILVPAYNEALTIIETVESLLMLDYGCYEIIVIDDGSTDHTAKLL
                     KERFHLEAVTCSINQRIPTRPLKAVSQKQLEHVRLTLLEKENGGKGDSLNLGINAAQY
                     DYFLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARILLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCQNNKIPYRIGYETDAICWSQAPSRLKDLCQQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIETFGVTIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRIYSQNNSSITFFDMVWVIYAAIYQCLVLHTVLTLVKVSSFIGYQR
                     KKNAWGQITRDKHKAA"
     gene            complement(37286..39427)
                     /locus_tag="TVR04_000465"
     CDS             complement(37286..39427)
                     /locus_tag="TVR04_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269180.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTSFYA
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRQRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPAAFYHALSRYNDTASHSLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLIGYIVGDDWHSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLDDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNRHQGFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAAGEWSRALTYRKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVITMIEY
                     PLLSWERPRVREVLKTSYRQVQAVWQEKRRK"
     gene            complement(39434..40867)
                     /locus_tag="TVR04_000466"
     CDS             complement(39434..40867)
                     /locus_tag="TVR04_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1269181.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKSAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPVSRNYRSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40873..41550)
                     /locus_tag="TVR04_000467"
     CDS             complement(40873..41550)
                     /locus_tag="TVR04_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1269182.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQRVKNTTSDDIEMIFELSRKDYDSTYQQDNPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41564..42259)
                     /locus_tag="TVR04_000468"
     CDS             complement(41564..42259)
                     /locus_tag="TVR04_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1269183.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSHQKKRSLRLTRA
                     DAQLLIKGDRSILLAYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNVDIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42387..43022)
                     /locus_tag="TVR04_000469"
     CDS             complement(42387..43022)
                     /locus_tag="TVR04_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1269184.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQIDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(43012..43551)
                     /locus_tag="TVR04_000470"
     CDS             complement(43012..43551)
                     /locus_tag="TVR04_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1269185.1"
                     /translation="MIKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFRGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43840..47562)
                     /locus_tag="TVR04_000471"
     CDS             complement(43840..47562)
                     /locus_tag="TVR04_000471"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1269186.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIAAAFSLGTASGH
                     TTVAAESLTSVEPIDGAVMVKSGAADQEQGSNELPEATDISDIAGTSDVTKVSAAVNA
                     DTVKEVQPVAVPLVEDQAHEETTDQSQPSSSIVPVTTDSSLETPEATSSEEPIAEQTL
                     RLHFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSA
                     EQAHKVSFLINNTKGDNITGDRTVELISPKVNEVWIDGQELSYYPPLAQGYIRINYYR
                     SDGHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADFNELGFLLL
                     DERQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNHVRLIGAKQVSPSS
                     IEASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYT
                     VTFHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKA
                     DETKVIGNFALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRDGKSVLVLDPYAK
                     SLAAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDF
                     TSDQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTY
                     SSSDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYN
                     HTANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKV
                     DGFRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQ
                     TDTVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVI
                     QYIAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEY
                     GRTKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAK
                     ATDTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDL
                     VIAYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEG
                     VVLTKDGVKLSGLTATIIRLRASQSDKETLGARTDQAAHHQEKLVAAQTAGEVSQFSA
                     KTLPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            48044..48589
                     /locus_tag="TVR04_000472"
                     /pseudo
     CDS             48044..48589
                     /locus_tag="TVR04_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48670..49125
                     /locus_tag="TVR04_000473"
     CDS             48670..49125
                     /locus_tag="TVR04_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269187.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            49125..49412
                     /locus_tag="TVR04_000474"
     CDS             49125..49412
                     /locus_tag="TVR04_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269188.1"
                     /translation="MTTWYDYMVRASEHAGSDGDLWFRYLYKIIKDGETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49405..49953
                     /locus_tag="TVR04_000475"
     CDS             49405..49953
                     /locus_tag="TVR04_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1269189.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDVDA
                     FYQESVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYGFQPDISMILEVFE
                     IAYGMEWLANYMSEHPEEFRYY"
     gene            complement(50123..51127)
                     /locus_tag="TVR04_000476"
     CDS             complement(50123..51127)
                     /locus_tag="TVR04_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269190.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVFISPTSISADSPPT
                     ITIKTAADKDISSNLPKVPLSNAKPEEKLEDTPQLPNEKGYGNDIRDLGKPEDLPKLP
                     DEKGYGNDIRKPEKTPELPNEKGQGDDLKKDEDLKKQRRELTEKLRGLKTVEEVLEFL
                     KMPIPGFVTDVDWQFLMAFVEKGTANKTFEKDKLTLLDIYSTSSGHMIWLGYLVPEKP
                     EPMPEPKPEPMPKPKPKPKPMPEPKPMPEPKPMPEPKPMPKPEPMPKPEPMPKPMPKP
                     EPMPKPEAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAVVSRKRKKH
                     "
     gene            complement(51212..>52030)
                     /locus_tag="TVR04_000477"
     CDS             complement(51212..>52030)
                     /locus_tag="TVR04_000477"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: protein motif:HMM:NF020596.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1269191.1"
                     /translation="GIDDFSTEIKNALSSHKALGLSYRTLVRYGHIVSVWGADIGEDG
                     RVKAVYVTDSDDRDAKTNNNKRVGLIRYSVKQDSNGKIRLTGYTGEDVGALSMHLYTL
                     SSAKEEWEDYFKKYPEVQENLENNVADSNKNSEDVEVSSVEFDFLNFKYPKNGDQVST
                     EGMRLTLKDTNVFNQLQAEVSFEEEDGNGWKKKDSGTFEEGKKYRLRIDVNKLALKIY
                     GHLSKNKLNVIVNGKAVNIQEIKKGSVETSFTMYSDSIGLEEINYWTDSFDNWS"
BASE COUNT        15314 a        11916 c         9868 g        14932 t
ORIGIN      
        1 catttgtact tattattctc attatactat attaaaccac atcttacgtt aaaatacaat
       61 gaaattataa gattatgact ccaaaataag ttgtttagta ttttgttatt ttagcaatag
      121 atttgattaa ggctagaagt catatgtctc ctgatatgat tatcactttc tgcaaatacg
      181 atgttctcat tacttgataa agagctgcca aaatcgttga tataaggctg aaaagcctct
      241 acttcattag caggtattaa aagaaagaca agttagctcc ttttcaatca attagtgatc
      301 gctaaagata gctcaaatac tcctgacaaa aagtcattgc tgtcttgtct agctaaattc
      361 gctagcttga ggcagtaaaa aatagactta gaaggtctct aagtctacag ttgatttctc
      421 ttatttgcca agctttgcct tagcagcatc agcgagggct gtgaaagctg ccgcatcatt
      481 gaccgctaaa tcagcaagca ttttacggtt aacttcgatt tcagcaagct tcaagccatg
      541 catcaattgt gaatatgaca agccattcat acgagcagct gcattgatac gtgtgatcca
      601 tagcttacgg aagtcacgtt ttttctgacg acggtcacga taagcatagt aataagaatt
      661 catgacctgc tcttttgcag tacggaacaa gatatgcttt gctccataat aacctttagc
      721 taattttaaa atacgtttac gacgtttgcg tgatacaacg ccacctttaa cacgtgccat
      781 taatattctc cttcaaataa ctcttataat tctagtaaat acctgttaca acctcaatct
      841 taaaggccag taaccattgc tttaatacgc ttgaaatctc ctgcatgcac catacctgct
      901 ttacgaagat gacggcgttg ctttttagtc tttccatgga aacggtgtga tgtaaaggca
      961 cggaagcgtt tcaaaccgcc tgaacctgta cgtttaaaac gtttagctga tgcgcggtgt
     1021 gttttttgtt ttggcatttt aatattctcc tcttaacata tagtgtaata tgacaattac
     1081 ttcttgtctg aaattggtgc aagctgcata aacatttggc gaccatccat ttttgctctt
     1141 tgctcaataa tagcaatatc ttgagttgcc tcagcaaaat cagccagtac cttagcacca
     1201 atctccttgt gagtaatcat acgtccttta aaacggatag aaaccttaac cttatttccc
     1261 ttctcaagga acttacgacc attacgaagc tttgtttcaa agtcaccctt gtcgataact
     1321 gggctaagac gtacttcctt tacagttaca acgctttgct ttttgcgttg ctccttttgc
     1381 tttttttgat actcaaattt gaactttcca tagtccataa gcttggcaac aggaggaaca
     1441 gcttgcggct ggattaaaac caaatctaca tttgcagcat cagctaaaga ctgagcttca
     1501 gataatggtt taatgcctaa ttgttcacct tcaagaccaa cgagacgaac ttcgcgaaca
     1561 cgaatctcat cattaatgaa tagatctttt ttagctatga tcttcacctc tttatttttt
     1621 tagagaaaaa cgaaagcgga cttaatgaat caagcccgca cacataatat cccataggaa
     1681 tttgacatgt agggccagac aacctaggtc gcaaggcgag aagctctcac ttctgctttt
     1741 ctcattattg acattctaac aaataaatca tgccatgtca attatttttt ctgctttttc
     1801 ctgaataaat tggacaacag ctgaaatcgt gataccggta gtatcaaaga taatcgcgtc
     1861 atctgccgcc tttagcggcg aaacttgacg atgactgtcc ttataatcgc gtgctgcaat
     1921 ctcagtcttc aaggtatcaa aatcagttgc aatccccttt tcaatatttt cctgataacg
     1981 acgctgcgct ctttcttcaa cagaagcaat caaaaaaatc ttcaactcag catcaggcag
     2041 cacaaccgtt ccgatatcac gaccgtccat gataatagca ccagtcctag caattcgtcg
     2101 ctgctgcttt accaactctt ctcgaatctc tggcaaggca gacacccaag aaacattatt
     2161 agtgacatca ttttgcctga ttgccattgt cacatcttgg tctccaagaa aaaccaactg
     2221 tgaaccatca gctgcttttt taaaagaaat cggacgctct gccaattctt gcaggattag
     2281 attgacatct tctttgtgat aaccattttt taatgcgata taagtcgctg agcgatacat
     2341 ggcaccagta tctaaatagg tgtagccaag atttttggca ataatcttgg ctaccgtact
     2401 tttcccactt gaggctggtc catcaatcgc aattctaatt gctttcatct tttcctcttt
     2461 aactatttga tattgacctc gtcacctgga ttggcatacc agtagccttg ggtcatgtga
     2521 tctgggttta gggcttgtaa ttgctcaaca gaaataccag cacgagccgc aatagatgtt
     2581 gctccttccc ctgctaagac tgtaattgtc tttcctgctg cctctgtgga aggtgctgtt
     2641 tcagtcttag aagggcttgt tgtatcacta gctgctgaag tactagagct cacttttggt
     2701 tttgcttttg tcttagcttt tgatttcgag ctggtcttct ttgctgtttc tttctgagtt
     2761 gatgccccgt aaaatcctgt tgtctcattt tgcttgttac tgccgctatt tgatgtatag
     2821 aagaaaataa aaagtatggc aacaataatg acaaagaaaa cacttaacaa ggcagtcaac
     2881 caaggtgtac taatgagtgc ccctcttgat cttcttgttc ttgttgtctt attgtcatca
     2941 acaatttttt cttcccatgg ttctttagcc atgattcttc ccccttgtta atttaacaaa
     3001 atcatattag aataatacct atgaaagtat ctatccttcc agaaaaatgc attgcctgtg
     3061 gtctttgcca gacctactct gctctttttg actatcatga tgatggtatc gtcaaattgg
     3121 ctcagtctga tgagtcaagt caactcatag atcctaatga tcatgatgcc atcttagcag
     3181 taaaatcctg ccctactaaa gcccttaccc tcgagtaaga ggcttttttt cgtattggta
     3241 ggcttcaaaa taatccagct tgatgaagtt atctagtaat ataacctctc ccttaaaata
     3301 aggattaatc gctaaatcat ctaaaaaata ttttttaggc cattttctca tgtaaaaaag
     3361 gtagctctta tcaccaacaa atagacaaac tgtcgactta gtaacctcaa ttttagtaat
     3421 tgaggcaatc atcagtctgt gcggagcaaa tagctttaaa gatacaattt tcaagacacc
     3481 attattctca attacaaaat aacggtgcag gccaagtccc actagtacag caaataaagc
     3541 aaacaaaaca aaaacacgac tcggtatttc tgttctctcg tacaacaagg acagaccaat
     3601 aaaaataggc gcaacagcaa ttgaccaata aataatagac caagacagct ctggctgcca
     3661 gtgatacctt actttaccga ataatttaat catgcttttc catcacctct aatccgttct
     3721 gagcattttg ggtgatgtta agctttttgg acaatgccaa gaatcacatc aactgccttt
     3781 tccatcgttt gcaggctcac aaattcaaac ctgccatgca tattttcacc acctgcaaaa
     3841 atatttggcg ttggaatccc cataaaggaa atctttgagc catcagtacc accacgaatc
     3901 ggctcgataa ctggcttaat agctaggtcc tccataacag ccttagctag attcacaggt
     3961 gtcatgtcct tttcaatcac ctttttcatg ttatagtact gatccgtcac tgttacaaat
     4021 acacgctctg ctccaagctg actattcatc tcctcagcta gctgtgttac aaaggccttt
     4081 ctagcttcaa aggagctatc ctcaaaatca cgaataatat aagaggcctg tgcttcttct
     4141 acagtaccag acatgctgtg taggtggtaa aagccttgat agccgtccgt tttttcagga
     4201 cgatcgtcaa ctggtaattg actatggaaa tccattgcta gctgcagggc attaatcatc
     4261 tgatttttag ctgtaccagg gtgaacattg cggcctaaca ccttgagctc tagggctgct
     4321 gcgctaaagg tttcatattg tagctcgcca agcggacctc catcaatagt ataggcaaag
     4381 tcaacatcaa aagcattaac atcaaactta tctgcaccaa caccaatttc ttcatcaggt
     4441 ccaaaggcaa ccttaatatc gcaatgctca atctgagggt tggcaacaag aaactcaata
     4501 gccgtcatga tttctgcaat tccagattta tcgtcagctc ctaaaagggt tgtgccatca
     4561 gttgtaatca gggtctgtcc caaatattgg ttgagatttg gaaaatcctc tggacataaa
     4621 gaatagcctg actgaccaag cttaatctcc ccaccctggt agctctcaat aatctgaggg
     4681 gctactcctt ctgcattaaa atcagcagta tccatatgtg caataaaacc aattttccga
     4741 gttaatttgc tgctattagc tggtaagctt ccaatgagat aaccattagc tggattgtaa
     4801 tgaatgtcct gtaggccaat agcttccatc tctggcttta gcactgttag agcaaagtca
     4861 gcttgactct tggtgcttgg agttgtagtg cttgctggat tgctccttgt gttgattttt
     4921 acatagttca gaaatcgttc taataaagtt tcgtatgtca tagaccacct cgataagttt
     4981 tcgttactat tatagcataa aaggacctaa aatacttgcc taagctcagt tttttacagt
     5041 gctttatctg ttctgttaca gttgcgttct cataaaaaga cagctgccaa gaaagctctt
     5101 gacagccttg attattcatc agcccatgcc ttaatcctca taaccatttg ggtgcttgct
     5161 ttgccatcgc caagtatctg tacacattct ttctaagccg tactctgcag tccagttaag
     5221 ctctttttta gccttgctag catcagcata gcaggctgcg atgtctcctt gacgccttgg
     5281 taatattttg taaggaatag atctgccaac cacctgggaa aaggcttcga taatatctag
     5341 cacagaatag cctgtacctg ttcctaaatt ataaatagat aggcttggct cttcagcaaa
     5401 ctttgcaagc gcagcgacgt gtcctttagc cagatcaaca acatggatat aatctctaac
     5461 gccagtgccg tccttggtct cataatcatc accaaaaacg ccaacacaat ccagcttacc
     5521 aacagctacc tgagaaacat aaggtaatag gttgttaggt atgcccttag gatcctctcc
     5581 taaatcacca gactcatgag ctccgatagg attaaaatac cttaacaata caatatgcca
     5641 ctcattatct gatgcataga ggtccttgaa aatctcctct agcatcagct ttgtcctacc
     5701 gtaaggattg gtcactgata gtggaaaggt ttctaaaata ggaatggtat gcggatctcc
     5761 atagaccgtc gctgaggagc taaaaataat atttttacag ttaaaggctg tcattacctt
     5821 tagcagggtc aatgttccag agatattatt gtcatagtaa tcaagtggaa tcctgcttga
     5881 ctctccaaca gctttgagac ctgcaaagtg aatgacactc acaataggat gcttactgaa
     5941 aatatctgtt agtagctgtt gatcgcgaat atccccctga taaaaggtca cttctcttcc
     6001 agctatcgag gcaacagcag ctaggctttt aggatttgaa ttgcacaaat tatcaatcac
     6061 aacaacgtca tagccagcag ctagcagctc aacacaggtg tgtgacccaa tatagcctgc
     6121 accaccagta actaaaatac ttcctaacat ggattatata cctgactttc taatagttac
     6181 taatattata actgattact cccaaaaagt atatctatca tttcatgtta aagaaatctg
     6241 gataggcatt aatgtagccc ttaccctcaa taagatcata ttctaacagt tttaagtcag
     6301 aagccacctg cttttgagta gcagttaact gactgtcatc actatttctg gtatccaaga
     6361 catcggtcaa aagagcgtag taaggagaga ccttggaatt cgtatgctct agcaataaag
     6421 aggtaaaatc actggaatta acacgaggtc tagccaattt attggcctga tgattgctcc
     6481 agatgaaata atctgttaga tacttgatct cctcatcatt cttaaagacc tgatctggat
     6541 aaaagccagg caaatgatca ccataaaaca caactgtgat aggcttatca accttttcca
     6601 atgctgataa aaaggccttt gttgacttgt cggtaatgct taataaattc acatagcttt
     6661 ttagactatc tgtctcagac ccgtccagac ctgctagact aacgtcaaca tctcttagct
     6721 ctgtgtacca agggccatga ttttgcatgg taatcactga aaagaattga cttcttttgg
     6781 gattgagctg gtctaaaata ttgtcatagg ttgattcatc gctatagctt gaactcattc
     6841 gtaccaagtg ctttggctta tcagctgaat cctctgtagc aatgaaggtc tcaaatccca
     6901 acttgttgta aacaattttc cgagaataat tattggcgct tgcaagatgt aaagcaatcc
     6961 tatccttagg cgaaaaagca ttgctaatag caggcgaata tttcaattta ggaaagacat
     7021 cagaatacaa aatcgaaacc gttggattga ggttatattt tggtaaacca aataggcttt
     7081 gaaactccat attagctgta ccaccaccat agccatcaga ggtcattaga ccactcgttg
     7141 tgatttccat gatatgatgg atctctggaa taggatcctt ggccaattga accccagaaa
     7201 tcctagctgg gtcagcaaag ctctcactca gtatataaat cactgtttga tcagaaatac
     7261 gctgatgcct ttgcttattg atatcagcag ctctagcttg atatttctga taaatctttt
     7321 gcatagcgct cttgctatag cctgaaggct gattaatggt gctggtggta acctgcttga
     7381 accaaacaaa gctcaaggat tgaaaccttg cattggttgt caggccatac cagtcaatat
     7441 caaagacatt gtagactgat gacagaactg gaataccttt tttgatttca ccatctttat
     7501 tttggctaaa tacaaaaagg atagaggcaa ataccaaaag gatggagcct attgacgtca
     7561 gtctaagata aagtgttggc aggatccttt ctctaaagta gcttttatac aaaatataga
     7621 tcagcagacc tgacaagact agtataaaaa taatactgat gagctgagtc agactaatgt
     7681 aattcaagaa aaacttaatc tctttgatcc atttcaaatc tgaaaacaat aagggctcac
     7741 ttcgctgctt gtatttttca atattgacaa tgctgatcaa agctccaatc accgtattga
     7801 caaataaagc aatgatatag ttgttaatga gcaaaaacac cagcgcaaaa aaaagcgtca
     7861 gtacaagcac ctgaaacagg gttgcacctg gaataatcac tgccccatga aaatcaccat
     7921 atgctgtgat tccagcctgg ataaagtaat taaagatgat ccctaaaaat aagctggtca
     7981 ctagagctaa tctaagaccc catcgcttgc tcaaaacccc gataaaagct gtgacaatga
     8041 ggtaataaac cacaaacatc agcatataag agcaaaagct atatttaaag agattcaagc
     8101 tgacaaggct tgactgacta tctagaggcc aataatcatt ttgcttaatc acagtcttaa
     8161 ataaagagct gttcagcgtt aagactgaaa aagcctgact aagtaaaatg acttggattc
     8221 ctctacttga ttggttgtcc tttttgaaca ggtatttttt taagagaact cctaaaataa
     8281 gcaggctgat taaagctgcc agactgagta gcatttcctg aatcgtacga ttgctgatgg
     8341 taaacctgct gttgttttta ttgatggcta aagtgatata actattagca acagcatagt
     8401 agctactgac agctacagaa acaataagca gttttgagga ggcatgcttg atcagcaaac
     8461 atgccattcc agctactaat actaagacaa gccatgaacc ataagcccct ttatttaacg
     8521 tgtttttgct taccgcaaca atagataaat aaagagatga aaggctaaat aatagcatat
     8581 caagcatttc tagatcaacc aactggcgag ctcttgatac tatcttcgtt attataatcg
     8641 tcacaccctt tcctaactgc taaaagctag acattactct ctgactcaga agtgattacc
     8701 tctgctacta attgacggac agtgacctcc caggtaaagc ctgaaagcac ctgctgatga
     8761 atagcttctt gcaggttaca ccgtttttct ttgtgctcaa tcaaatgatc caactgtctt
     8821 ttaatatcag agactgtatc atcaatgatg attccctgtg acgggctcgt tatcacttcc
     8881 ttgacgccac ctctatctgt tgctaataca gcacatttca acatacctgc ctctaataca
     8941 gctgtcggaa gcccttcagc atagatggac ggattcacaa aaatatcaga ttgggacagc
     9001 aaagacatgg tctcagcaaa attcagcttg cctgtaaaga tgatggactg atcctcttta
     9061 tagctatctc ttagtgaagt aagcaaggga ccatctccag caaccaccaa gacagccctg
     9121 tccttatatg tcagctgctc aaaagcctcc agcagcaaaa gaatcccctt ttccttgatc
     9181 actcgacctg caaaggtaat aatgacctta tcctgcaaag ctggtaaata agcctttgac
     9241 ttaaagctct cataaagatc agaatcaact gaattgtaga tgacgccctt ggcttttatt
     9301 ccaaaggtct tgagccatgc catactgcgc ttagacaccg cataaaagtc aggctgatag
     9361 gctttgacaa aaaaggtaat cacatgctca tagagtttag caaacaaatc tagtagctgg
     9421 tgacctttaa cattttcgcc cacctgaaca tagccaccac catgctcgat cacaatacta
     9481 gggagggctt ttcttttggc tagcttcaag cccatgaggc ttgtcaaata aaatcgtgta
     9541 ttgcagatca caaagtcaat acgttcttcc atcagctctg ccagcatgct atgatacaga
     9601 tcattcttat ctaaaatcgg atagcgctgc ttaaatagct gctttgaagg aaatcgataa
     9661 taagtaatgg cttgatctct ttcaataggg ctcagctggt ggctgttgct ggttacaatg
     9721 atgatacggt agcctaggct cactaattgt tgcgctattt tttctgtata ccgctctact
     9781 cctcctagat gagggcttgt aaagccgcta aaaatggcta ttgttttcaa agcttttccc
     9841 ttcttatgta taatattgca gcatggttcg agtaatcata gctaggatca atagcagcga
     9901 gccaataaga acctgtttat tgcttaatag gccttgggcc ttttcaaggt atttgttatt
     9961 agaggctagt aagaccaaca ctaaagggat cacccccaaa aagtacctat cttgaacccc
    10021 tagcacatta aggtctccaa ctggcgtaaa ggtcaaataa aggctaaagg taataccgcc
    10081 tattattcct aaagacatca atcccatacc aaagcgagat aaggccggca gctgaagctt
    10141 gttggcatta gtgatgacaa cagcaaaata ataaaccatg ctaattggca taagctctac
    10201 cataccgtat gataaaggac caaacatgta aatccctgaa ggattaagga tatgagcaaa
    10261 catgtgtctt agcagcataa agccatacac tatagggtgc cttaacacag tcagcagctg
    10321 ctctttagca ttaaccttct ggagaaagtc agccatatcc acctgaggtg acttgatttg
    10381 accatatacc tttaaccaaa aaacagtcac aaccagcacc gtcagaattg acaacagctt
    10441 tagcagaaac gtgcgagagg cttttgctcc aaattgacgt gaagggataa aaagcagtaa
    10501 caaaatcaat aaaatataag gtagcttagt aaaggtaatg attgagcaca gcagggtata
    10561 ccaaaagagc ttggataagg gaatcttttc agttgtagcc atctgaacaa ataaagaaat
    10621 cgtcagaata atcaatccaa tagagacaca atcctgatta taggaaccag caagatagat
    10681 attcattgga aggagactcc ccacagcaag cagctgcttt cctgctgtca gcaatcgtaa
    10741 ggcaacaaag accaagatgg cataggcaag aacattacaa agcctaccta aaaggtaaga
    10801 taagcccatg gtcaagccta aactccttcc aataaacagg cctattgcct gtggtatgta
    10861 agcaaagtta taatagccat ttgttgagcg aatttcctta aatgaaatag cctcatcggt
    10921 atggtctctg ctccacagct gaaagcgtag gggcttgcca ttgttgtggt ccatgagatt
    10981 aatgtcatca gtcaccagca gccttgagtc atcattggtt aaattaagat ttccctcaga
    11041 taagtataag gctcttgcaa agtgaaccct ctcatcagga atatcattga tcggtgagat
    11101 gaaggcagag acagaaccca taaccacaat aataagcact gtcgcatatt caatatttga
    11161 aggtaaaaag ataatcaaaa gcgcagcaat tgcaactaat atcactaaaa atttaatggg
    11221 taaatccgtt gattgtgtat ataaaagcag caaaacaaga aaggcaccaa gcaaaacaag
    11281 caaagcctta ctcgcctttt gcaatttgtc aaataaggta tctaacatat cctatttcct
    11341 tttttccata atgtacaagc catatgacaa tagcagccaa atcatcattg aaattataaa
    11401 accataggta actccaatca ccccaaagcc tctagccaaa gaaccggtga tggctagtga
    11461 ggagataaag gacacaacat aaggtatcac aagcaagtgc tgctttctga taatggtaat
    11521 caaattatca atataagtgg caaaggtgct gataatccct ccaaaaataa gaagcataaa
    11581 atcaagctgg taatgcctta aatcaatacc ataaacaagc gatagcaccg gcagccccac
    11641 aaaatagcta gcaactaaga tagctaggct tgctaatagc agcactagac tgagacgatg
    11701 ctctaattgt acaaagctct tcttgtcctc ttttgaatgg taaatggcca gctgagtgat
    11761 cataggcctt aaaaacaaga aaatcaggtt aatcataaaa ataggcataa acaaaatatt
    11821 aaattctgtt tgaacaccgg ctgggatcag ctgctttgag taaagctgct ccaaaacaaa
    11881 cttgggctgg ttgtagatat aaatgagtaa aaaaccattt aaaaagaggg gaaagctctc
    11941 cttcaatagc cctaagatgc tttgagcatc aatacgacgc tcaagactcg taaaggaaac
    12001 tgaaggggtt atgtcaaata gcacaataca agccactgaa ataaaacata tcacgatcaa
    12061 agacaggact agctgcttgg tcagaaccag acagagcgta aagccaagga tcaccagcat
    12121 atttcgataa aacaaggatt tgccggcaat atctaagcgc tctctttgtt gaaacattcc
    12181 ttgaaacaca tcagaaatgg catctgtgca acgatacaag caaatcaacc aaatcactag
    12241 ccccttaaac ccactatagc tccccaaata aatataaagc actgaaatgg ctatcatcaa
    12301 gaaacaggtg actagtcttg tataaaaata gtctttgaag cggtacttgt gtaatatatc
    12361 cgttgattgg aaatttctaa cctgaaataa gccaatagta atcagctgat ttccaatagc
    12421 ataggcaaag ctaaaggtat ctgaagctga tttagataag acccgagaca caatcatcag
    12481 taaaatcact gatattagtg ctgtcgagct ggttcccaac acattccaaa taaaaatcga
    12541 ctgatccgat tgaatcctac tgctggtttt catcttcttc ctgcttttcc ttctcattaa
    12601 gggctaaata ctgaatcatt tttttaagct taatctctgt ccgagacaat ttttgagtga
    12661 taaaaaattg gttgatgatg agtaaaaaaa tgattgatag aaaaacaaaa tttgccggcg
    12721 attcaaagcc tagcagcctt gaaaaataaa ccgcagcatt tggaaacagt gacagcaaaa
    12781 gcactattaa agagaaaaag agccaaaaaa agctatcttc aattaaaatt ttggatctgc
    12841 gaatgctatc tagtataaac atggctgtca ataatgcaac aatgatcaaa atcagctgta
    12901 acccaataaa catcctctta cctctttcta aagttttgaa ttaaaataat cgaaataaac
    12961 atgtgaacca tgtatttaat agatctagaa agagtgaggt agctttgacc agccagccta
    13021 tcattcattt gcacctgaac ctcactcacc ctatagcctt gtcggataag ataagagatc
    13081 gtatcaggct ctggagtata gttaatatta gttgcaaaaa tcctgatcag ctcctgatta
    13141 aacattctca taccagaggt tggatcggta atacgctttc ctgtggttag cttgataaaa
    13201 aagctaataa ggctattgcc catcattctc aaggatctat tcttttcagc actgacaaac
    13261 cttgatccaa tgacacaatc agcaccagcc ttgattgaat cactcaaagc ctcaatatac
    13321 tctggcaagt gctgaccatc tgcatcaaac tggagtgctt tggcataacc ctttttaaag
    13381 gcgtacttaa agcccgtctg aatagcacca gataagccaa gattttccgg caaatcaatg
    13441 atattgtaat ggttatgatg acatatctct gatgtccgat ccgaagagcc atcattgata
    13501 atcacataat catattgagg aaaatgtctt ttgatatttt ccactacttt ttcaatcgac
    13561 tcctcttcgt tatatgctgg aatcattacc aataagtctt ttttcatatc gtcaaatatt
    13621 ctctctattc attcgtctaa acgcgtcttt ttagcaatcg ctttatgata taacggatgg
    13681 ccttagctgg tccaatcaca atatatttta gggctccctt tatacctccc atataatcaa
    13741 aatcaacata ggtatgcggc acactgcctt cacgcaggtt taagagctta ttatcaataa
    13801 atggtgtcaa tagcttttca tttcttgaaa ttctaaaatc atagtgtctg tcccaagcaa
    13861 tataaattaa gagacgttca atggcatgca ggatcgaatt ttgaggcaga ggctctgctg
    13921 gaatatcagc ctcacttagg tctaagtcaa acaagggctt taaggcatcg tatttaaacc
    13981 aaacaaaggt gccataactc atgacaaagg tatccatcgt ctgaaaatca atattttttg
    14041 taagccccat tgcctgccaa agctgattca tttcaggggc aataaggtgc tcattccaag
    14101 cgtcaacaat tttattaaaa cggaaaaaac ttggaatatc tgctatcaca ataccgatag
    14161 catcagcagc cagtgctgtt aggatctgat ccgctggctt caccatcata tcaatcaatt
    14221 cagtgcgcca ggattggccc gcccaaaaat ctgcttcctt tgattttttg gtatgaaaat
    14281 gcccaatata atcatattga gacaatcgtt cctttaaggt cagcattggc aagacatctc
    14341 gaccgatatt tcctgtcacc aatatgtcag cacttgcccc gctttctcgt agaattcctt
    14401 taatctcagc ctttttagcc ttgctatcgg tcgttatgag caagtcataa tcaaaatgaa
    14461 aatggctaaa tgcttctaga aactctgaca ataaatcaac ataaaaaaca tgaagatgaa
    14521 cagcaatttt cttgcttgga gcaatgctta tcggctgatt gggcaggtat ttatgcgcta
    14581 gaagatactt agcatctggt aggtggacct gcgacatgtg atccacaatc aagctggcag
    14641 ggtatgacgt tttttggtca ataaaatcca aaaggtaagg agcaatgtgc tggttagcgt
    14701 caatagcctt aaccttgata aagggcacat ggtgctttaa gatggctgtc ggattgtaat
    14761 aagagaaatc cgcatgcagc atagaggacg agtcctcctt ggtcgtatca aataccgtct
    14821 tgtatcgaaa gccagcctcc acaaagacag tggttattct ggtttcataa ttgtggatca
    14881 catcttgaac gtctgttagc tcaacgatat tttcccaaaa ctgcctaaat tccttactat
    14941 gaacgaggga ttttttgaag ctgataaaat agctctgaat atgctcttta aaggccttgg
    15001 tcgctcgatt gttggtcatg ccccagaaat caactgcttc atctgcttca tatttgagat
    15061 aataaggctc catatcccaa agcggaccaa agcaggtatc gttcataatc gtgattgagt
    15121 caaagtcaac aaggtgctca cagcctaagg ccttcatacc atcatgccaa gctgcaaaat
    15181 catagccttt attgtgtcgt tgaataaact gatccatcaa atgccgctgt tcaagctgct
    15241 caaggtcctc ttgatggata tcactatttg aaataaagac aatctttgaa aacaaggctc
    15301 tcatctgttc gagctggtaa taaacatgat cgcttacctt atgatattta ttgaaatgca
    15361 catacaataa aatacgcttc attttttcct cctaaaaagc tcaagcagct ttgataggta
    15421 cctccaacga cgtgaggtaa ccacacaatt gtattgatgg gttagcgctt caacctcttg
    15481 cctttgatga tcaagctgct gctctagctg atctatcctt tctgcctgta aagcctcctg
    15541 atctaccagc gtctgtcgta attcatgaat ggtatgactt aattgatgaa tccgaatttc
    15601 atttttagcg tcctgcttta gtaatgcttt tgcaatagct tccatattgg ctgtagggta
    15661 tttagacaaa taggacagct gggtctccaa caagccttga atacggccca gcattttttc
    15721 ctcggctacc ggccttgagt ctgaattatc cgtcagtcga taaacagtgg tcgaatcctt
    15781 caaataggct agagaggttg actgaaacag ctctaattgt atgtcaaaag tgtcgtctga
    15841 cgtctccaaa tcaatgcgtt gattaactgc cctcatcagc tcagcctcca ctagccaggt
    15901 tgacgacatg gtcattccct ttaaagcaag cattttctca taggtatctg ttaagggagt
    15961 aaagccactt tcaaaggcat tgccctgaat aagcttacca tcagtatcta caaaatcaaa
    16021 gtcagtatta gaccattttg aatctggtga gctatccagc aaatcaacct gcttttgtag
    16081 cttgagagta tcagtccaat agtcatcacc atcacatctg gcaatatact gtccctttgc
    16141 ctccaaacaa gccttgaccc aggttcttgc aatcccaaga tttacctcat taacgatgag
    16201 tcgtatacga tctggaaagc tggcttgata gtccatgagg atctgtctgg aatggtctgt
    16261 cgaagcgtcg tcaatgacaa taatttcaac atcaaagctg gtctgttggg ctaaaaagct
    16321 gtctaaggcc tctgaaatcc aaggaccctt attataattg gtgcaaataa tagaaacttt
    16381 tttcatagga tgctttctaa tgacaattat tgattaatga gccagctacc atttctttga
    16441 tataagccac tggcagagtc caaagcagac aggtcatctg gagcaatatc gtttcgttga
    16501 agcacgatta gcggagaatg atcagctgtt gaaaagagca gcatttgccc gttttgatcg
    16561 cgaacagtta cctcaagctt taatttgata tcatttagct gtgagagctg acactggtag
    16621 gatatattct tgtggccagg accacttgtc ggctgatcct gtgaattgtc attgtatacc
    16681 caaatattgc ggtcaatgtc agtcaatgaa aaggcaacat aggtaggctc gtcctttagg
    16741 acatgatagg aaatctcaaa ggaaatgggc tcatctggac taaggcttgg cttagaggtc
    16801 aacctcacct ctaactggct tgccaaatca gacacaggct cagcaacagc tccttgctca
    16861 tcatttttca attcagtatt atcaacactg tattggttag caacatcaaa gggctcacca
    16921 taagccttga caaggccatt ttcgatgaga actgcgcgat tgcagtattt tttgacagcc
    16981 cccatatcat gagttactaa tatagtagtc ttgccgctct ccttgcgctc catgaagtag
    17041 tcattgcatt ttcgctgaaa ggcctcatca ccaacagcta acacctcatc aagaatcagc
    17101 acatctccct gtgccttgat agcgacagaa aaggcaagac gaacctgcat gcctgaggaa
    17161 taatttttta atttttgatt catgaaatca tgcagctcag caaagtcaac gatatcatca
    17221 tacatatcgt caacctcttc tgtggtaaag cctagcattg ctccattcat gtagacattt
    17281 tcacgcccag tcaactcagg attaaagccg acaccaagct cgatgaagga caccattttc
    17341 ccctcaactg tgacctgccc tttttctgga acgtaaatct gagaaataat ttttaataag
    17401 gttgattttc cagagccatt tcgtccaacg atgccaaaaa aatccccctt atacacgtca
    17461 aagctaatat cccttagcac atgctgctcg gtatagccct taatgccttt aaatcggtta
    17521 acaagagcag tacgaaagct cttggttgcc tctgttggca gcttaaagga cttactgaca
    17581 tgatcaactg ttactgcaat ttctttatta gccattagat aatctccgca aacttcttag
    17641 catttttatt aaacactgct accccaagtg ctaataggac aaatggaatg aggtaaggaa
    17701 tgatgatata gcaccaattt gtcgacattt gccaaatcgt cacatttgct ctatcaatca
    17761 gcagataccg caagtcttga ataatctgtg ctaaaggatt aagcatcaaa atcttggcag
    17821 caagagggtg tcggtcaaac acaaaggtaa tcgggtagat gatgggagtc acatacatac
    17881 ctgcctgcaa tagaacctcc caaacctgag ccaaatcacg ataataaaca aagacggtag
    17941 aaagcattaa ggccacacca actgtcagaa cagccagctc agcaaagagt ggcaaggcca
    18001 ggtaagcgtg aggagacagg gtaaccccat tgatagctgc aaaaaccaaa accactaata
    18061 ggttgattga aaagttaatc aatgctccca aaaccgctga aaaaacaatg gtatgctttg
    18121 aaaaattcaa ttttctaagc aggtctcctc gcgacacgat agagaccatt cccatactgg
    18181 ttgcttctga gaaaaaggac caaatcacat tggcaagtaa gagagcaacc ggaaaatgag
    18241 gaacgtcacc accagttcgc aaaaacctga taaacaccaa atacatgatg gtaaacatca
    18301 tcaaaggctt taagatagac cacaaataac caatagcact gccctgatac cttagtttaa
    18361 agtctgtttt aacaagctct ttcaaaagaa tacgattctt tttactcaat aattccatta
    18421 ttcttttctc ctatagccaa atttggtcat tatcaatgcc ataaaaacaa gggtatgaaa
    18481 ggcacgattt ttccgaaagc catacgcctt taaatcagat agacgctgat agaaaggctt
    18541 atccaaaagt ccgacgtaag cctcaatcag tcttctgtca gtcggcttta gctgcaagtc
    18601 tagcaattgc cttgcttgat gttgactaga gacaataagc caccaatact tctctatgag
    18661 cttatggggc ttacgccact gcttcagtcg cttagaccag gttcttgccc ctaaaacatt
    18721 agcatcatgc tgacgataga gctctgttgc cacatctaga taaacaagct ctccctgcgc
    18781 tgctgcaatc aaggctaaat accagtcgtg catcactaca tgctcacagc tcagccactg
    18841 ctttgctaag gcatgagtaa tcatcatggt gccacctgta acggtgtttt cagtcaactc
    18901 ctggactagc tgagtattgg catgatgtga ctgtgtttgg atcatgctct catgacgtac
    18961 ttctaagtcc tgattgacca cctttaggtc tgtgtagacc agtaaaggct cactgacctt
    19021 gtgcttttgc gcttctgcca gagtgagctc taatttattg tctaaccaca catcatcttg
    19081 gtcactgaaa aaataaatat ctgccttttc atacgttaaa agggtgtaaa agctttgaat
    19141 cacaccgagg ttttcttgga catcagcatt aatcaagcga attcgcggat cctttttagc
    19201 aaaagcctga atgatggcaa gcgttttatc agtagaccca tcatctctga ccaataaggt
    19261 ccaatcctgc accgtctgcc tttgaatgct ttgtatttgc tctgctaaaa accgctcccc
    19321 gttgtaggta gacattaaaa tattaatctt catctaaaaa taaggcctca tactctccta
    19381 caattttctc ccaggtatat tctttggcaa tgatttgctt agctctttct cccaaatcag
    19441 caaacgattc cttttgatca accctgttga tcagtccagt aaggctgccc ttttcttttg
    19501 tccaataaag ggctgctgtt ttagcaactg attgattaaa ggtcactccc aaaaccaaat
    19561 taagctgggt atgggctagg gcctccaaaa gacctggatt ggtacctcca acctcatgcc
    19621 catgaatata agcaaaggca tgctcacgaa tataggctaa aagctgctta tcatactggg
    19681 ttccaataaa ttttacacgt gcgtccttat cacagccagt tgcactaacc agccgctcaa
    19741 aataaggatt tttgtcatgg ttgcaaataa taaccaaatc ccgctgagta gatgatgcca
    19801 taaactctct aatggctgtt tcatagttgt tttcaggaac aaagcgcccc aaaatcaaat
    19861 agtattggtt ttctgttatc tcaaatgttt gaaagtaagt tctgactttt tcatctgatg
    19921 tagacagaca agaccgctct gtttctgtcc cataggcaat aaaagtcgtt tttgcccaag
    19981 gataagtctt tttgatgtag gcttcaatgc caatattatc tgagatgacc aaatcagcat
    20041 gctttgtcat ttgcttttct gcgtatttca ggtattgctg aacaggctta gaccacttgg
    20101 aacgcttcca ttccagccca tcaggattaa tcaacaaacg cccgccacgc tggtggatct
    20161 gctttgcaaa gggggcaata aagcctccaa tagtattgcc tagaacataa aaaataggct
    20221 tttgaatatg atacctgtca atataagcta gagcatggct aatagccatc atatcgtaag
    20281 caattactct agctggaccg agcttaggag ggttgatata aaaacaatct gctcccttgt
    20341 aaacaaaatg ctccttgtgc ttgctatcgc tcaagcaggc aatatggtag gtaatgcttt
    20401 tgttggtctg attagtgact aattcttcaa caaaggtctc aaaaccacca tactttgccg
    20461 gtaacccgcg acttccaatg atgaaaacat cctgcatagc acactgcccc attctaaaat
    20521 ataatcagta gtattatacc atataaacag gtcttatgcg acataaaatc catgaaaaga
    20581 gagccaatct cctagatcag ctccttagtg ctatcactta ttcattgctg ttgcttgtaa
    20641 aaagcctcca gggcttcttg ccaggtagga atcacaaaac cagttgcctt agccttatca
    20701 agattcatgg ttgagttaaa gggtcttttg gctttagcag gaaaagccga tgaatccaca
    20761 ggcacaacct cgacagctgt ctcttttaag atttctctag caaaatcata ccaagtggtg
    20821 tcttctttag catcatttga caaatgataa tagccataag gcttgcgatt gtctgctaga
    20881 tagcacataa actcagccaa ggtcctcgtc caggttggac gtccatgctg atcattgacg
    20941 actgtcaggc gagagtgggt cttagcaaga ttttgcatgg taaacacaaa attcttacca
    21001 taatgaccaa acacccatgc agtgcgaata atgtaaaatt gcttggtata tcgctcaaca
    21061 gcctgctccc ctaagcgctt agcacgcccg tactctgttt gaggatcagg agtatctgtt
    21121 tctagccatt cctgaccagc tggctttttg ccatcaaaaa cataatccgt tgaaatataa
    21181 accaaggtcg ccccatagcg ctcacaagct ttggcaatat gctcagtacc agctacgttg
    21241 atagcttcat tcagcgcttt tccttcctct tcagcagcat caactgctgt gtaggctgca
    21301 cagtgataca ctaagctagg cttgacctga gcaaaaacct cctctacttt agttgcgttg
    21361 gtaatatcca tttcagcaac atcaacagca acataatcga cgcttcgttc gtctaaaaga
    21421 taacgaagct ctgttcctaa ttgaccattg cttcccgtaa ttaaaatcat cttttctcct
    21481 tttaaaggcc ttatctcttt gagccaatca cacagctcac tctcatctaa tcctaagaga
    21541 ggcctttttg atcaactgac cctggcaggg cctttgttgt ggtatcgtat caaccttgct
    21601 ttttatctag ctaccgaata cctagggcaa ttctcgcata gcggctcatc ttttcaacgc
    21661 tccaaacagg gtaccagacc aactttacct caaccttggt cacctctgga acatctctca
    21721 tcgcatcatg aatgtgatca gtcaacaaat ccgccaaagg acagcccatt gtggtcaagg
    21781 tcatgtcaat ctcggtatga ccattgtcat caaaacgaat ctcatagacc aagcctagat
    21841 tcacaatatc aatacctagc tccggatcaa taaccgtttc caaagcttca agaatccgat
    21901 ccttgatagc tgcaacctgt tcttctgtgt attttggtgt ttcagtcata gccattcctt
    21961 tccctttttt cgaagacttc atgtgattcc aaagtaacaa tcagcccaag aagaccaaca
    22021 catacagccc acaatacact ctacgacagc caaaactgac tggtctgtgt agctttttga
    22081 gccagtcctg cactggcgct tttccttagt cgctgattat taaaagcata gtaaactagc
    22141 aagtaaactt ggaatcattt gcagcggagt gctcgctgta aaaaagaaca gctacctttc
    22201 aggctcgtgt tttgttttta gctcgccgtt aaaaaggaca ccctatttcg ggctcgtctc
    22261 ctatttttag ctcgccgtta aaaaggtcca ctggaccttt ttaatcctca atgaagtctc
    22321 tgagctgctt gctgcggctt gggtggcgaa gcttacggag agccttagcc tcaatttgac
    22381 gaatccgttc acgagtgacg ttgaagacct ttccaacgtc ttctagtgta cgcattttcc
    22441 catcatcaag tccaaagcgc aggcgaagaa cattttcctc acgatctgtc agtgtatcaa
    22501 gcacttcgtc taattgctca cgaagaacta cacgagtggt gtaatcaact ggattttcaa
    22561 tcacctcatc ttcgatgaaa tcacctaaat gactgtcatc ctcttcacca attggtgttt
    22621 caagagacac tggctcctga gcgattttca gaatttcacg caccttatca ggggtcatct
    22681 ccatacgctc tgcgatctgc tctggagtag gatcctgccc caattcttga aggaggttgc
    22741 gctgctcacg cactagctta ttaatggttt cgaccatatg cacagggata cgaatggtgc
    22801 gcgcttggtc tgcaatggca cgagtaatgg cctgacgaat ccaccaggtc gcataggtcg
    22861 aaaacttgaa gcccttggaa taatcaaact tgtcaacagc cttcatcaag cccatgttac
    22921 cttcttgaat caaatcaaga aattgcatgc cacgccctac ataacgcttt gcaatcgaca
    22981 ccaccaagcg cagattggcc tcagcaagac gctgcttagc ctccatgtca ccagcggcta
    23041 ctgcaaccgc taaaaccttt tcctcatcac ttgtcagcag cggcaccaca ccgatctcct
    23101 tgaggtacat acgcacagga tcgttgacct tggctgaatt acttccgata agctcctcgt
    23161 ctgtcagctc ctctggctta ggctcttcaa cgacgtattt agatgaggga tttccttcct
    23221 tatctgtaat ggaaatgccg ccatctgtca agcgctcaag caaatcatca atttggtcag
    23281 catctaaagt aaatggaatc acgagttttt ctgtgacctc atcatcagta gctgttcctt
    23341 cctttttatg atgacgaata aactccgcaa cttgaacgtt aaaggttgta acttcttttt
    23401 cttttgccat attttcctct attccatttt tcttttttca gcaatgaaac gctctaaagc
    23461 ctccagagcc atctggtggt cacccttact gctagattcc ctgatctgct ttccttgcct
    23521 atgcagctct ctttgcttta gcaatgtcat ttgctttgat aaaatatcct cgatctcacc
    23581 gctagctatc tcatcaggga gattttcctc taaaacccgg taataggctt ggttaacctc
    23641 ttcagaaagc tgtgataaat cataggaagt aatctgccct gtggccttta gctgctcata
    23701 caacgtctga agagccggtg tatcaaaaca aaaatccggc cgatgacgaa attcattgag
    23761 caaatagtcg tgatgaagca ggcgatgcag gaggtgactt tctgttttag ccaaggctgt
    23821 catgcttttg ttaatcggta aggtcacaag agatgctttt ggttgactag cctgtccttg
    23881 taagctttgt ctatcttgta gccttaaagc atttaccgat tgctccacct gaaaataatc
    23941 aaaatccggc agcaaatcag ccaccttatt aatatacgaa ttttgtgcgg tgattgaggg
    24001 tgcttgagca ataatctgtg atatatgctc cacataagca atctgcgatt gcaggttatc
    24061 catattttca ggcttcaggt gatcaatcaa aaactcaaca ctgctaatgc gcgagtgctg
    24121 gagcaattct gctagagcct ctggtgaatg ctgctgaaca aattcatcgg gatccattct
    24181 atttggtatt ttcacgatct ccacttgaaa atctgccagc agctcaagag acttggcaat
    24241 agcattttgc ccggcgtcgt caccatcata agtcaataca accttttgtg tcagctgctt
    24301 gaggtgccta acatgctctg gcgtcaaggc tgtccccata gaggcaatag cattgccata
    24361 tcctgcccga taggctgcaa taacgtccat aaagccttcc atcaaaaaga cctcatgagt
    24421 cttagcgatt atcggcttgg ccttatcaag gtggtaaagc tcataggact tgttaaataa
    24481 gaccgtagcc cttgaatttt tatacttagc ctgctgcttt tctatatcct ctcttgccca
    24541 gatacgtcct gaaaaagcaa tcatattgcc cttatcatca cataagggaa acatgattcg
    24601 atgacgaaag gcatcataaa cagcatttga ttgttcagaa acatgaaaca agcctgaggc
    24661 tgttaattgc gcctcagtat acttttttga caaggcctga taaaggtagt ccatctcgtt
    24721 aggcgccaaa ccaatccgaa aatgctctat tagctgatca tcaagccctc tttgataaag
    24781 atactcctta gctctttgac caatctttgt cgtcatcaaa accgcatgat aaaacttagc
    24841 agcatcttca tgaaggtcaa ttaaagcctg gtgggagtgc tgcttttggc ctaggctagc
    24901 ctgacttgga gcaatagtaa ctgccatacc ggccttatca gccacaatct gaacactttc
    24961 taaaaaagga acctgacgat attcctcaat aaacttaaaa acatcccccg acttaccgca
    25021 gccaaagcag tgaaagaact gtctatcttc aatgacatta aaagagggtg ttttttcttt
    25081 atgaaaggga cacaatccaa ggtagtgccg accagcccgc gatagatgga caacttctcc
    25141 aataacatca acaatattga cattatgctt gatctgagaa atcatctctt tgtcaatagc
    25201 caaaccgtca cctccccaca aaaagcccat tgtaaattta catttcatta taccattgaa
    25261 aatgagcttt gtaaattgta aaagcacaat ccttcatcat ctaaagcccg ctacatcaag
    25321 caataagcta tgctaaagca ttgacgtctc ttatgatcac tagcttgact agtagtacag
    25381 cattaagtag ctcatcagtc cttgataagc tcttctatta gcctttttga cctatttgtg
    25441 ctatgataag attatctgaa aaaaggggag tcaatcatgc tcaaagaatt aaaagcattt
    25501 ttatttagag ggaatattat cgacctagca gttgcggtga ttgttgggag cgcctttagc
    25561 gctattgtca catcatttgt caacgacatt atcacaccgc tgatcctaaa cccagccttg
    25621 aaagctgcaa atgtggaaaa cattgctcag ctcgcctgga atggcatcaa atatggcagc
    25681 tttctcagtg ctattatcaa ctttttaatt gttggtacca gccttttctt tgtggttaag
    25741 gtcgctcaaa aagcaatgcc taaaaaggga gaggaagagc ccgctaagcc caaaacacca
    25801 actcaggaag aattattact tgacatacgt gatttgttag ccaaaaaata actcaaagct
    25861 cttacagcag ctggacctgt ccggctgctt tttgatatac aagcacagag cacttagcga
    25921 tcaaaagata atagatcggc tctatttgct gttttagcat accattgcta tttttatcag
    25981 cagcaagctg aggtaaaaaa agacaaacta gtatcctcat actggtttgc cttcaaacta
    26041 aggcagccta caaagggccg ccttttttat gatgattaga attttttacg tttgcgagct
    26101 gcttctgatt tgcgtttacg ctttacagaa ggtttttcgt agaattcacg cttgcgtgat
    26161 tcttgaagag taccagcttt agtaacagaa cgtttgaaac gacgaagagc atcatcaagc
    26221 gattcattct tacgtactac tgtttttgac atatgtttca cctcctcaag atattgtaac
    26281 attttcacgt tctagcttat cttacatgat ttttcggaaa aagtcaatga tcttttcttg
    26341 attttgaggt cattctttaa aaaaacaccc taaaattagc tactacatta ggctaataga
    26401 tagatcactt atcaaggcta ttctactgca tttcctgtta ataatgctgc ttcttgaata
    26461 aaggccttgt atttgccatc cttgtttaat tgcttgatca ccttattgat ggtttgcctt
    26521 aggtcatcac ttccctttgg catagctaca gccttagcat ctccatcact tgcctgcaat
    26581 ttaaatggtg ctaaagctaa gtctttatgt tgagctaaaa agcctgcagc tactggtgct
    26641 tccaaatcaa cagcctgcac ctgcccagat ttcaattcgt taatagcctc gcccatcaca
    26701 gttagagaaa cacagttggc tttattaagc tgctccttga ctaggccctc ctcgatgctg
    26761 cctttttgaa cagctacctt tttgccagct aagctatcct tattagcata atgcttggca
    26821 tctgacgctt tcaccaaaat agcattttca gtttcatagt aagcctcaga aaaatcatac
    26881 actttggcac gctctttggt gtaggacaaa ccagaaatcg ctatatccgc cttaccagtt
    26941 tgcagactgg ataagacatt atcaaaattc atggcagaga gctctagctt aacccctagc
    27001 tcatcagcaa tggcctgtgc cagctcaatg tctgctccga caatagtatc cttgccgtca
    27061 accaaggcct taaattcaaa aggagcatag tcagggctaa cggcaaccac cagctttcca
    27121 ttttcctgga tcctgtcttg aaggctcgtc ttgttagctt ggccacaagc tgccaaagca
    27181 aaaacagata ccatagcaag tgctccaact aataatcgct tcatgttcat attataatta
    27241 ttccttttct tattgataag gtttattata ttgtattatt attcaacagt caagttttta
    27301 ttgaatattt tttaggcact gtgatagtct gtttaatcct gcctgtagaa cctgcggctg
    27361 acaacaatag ccgattctca catgatttgc ttgattaaag cgatttcccg gaacaaccaa
    27421 ggtaccataa tcctccagca gcctcaaagc aaaggcttca atgtcctcat cgatgtctag
    27481 cctaacaaaa gccgttgata cctcacttgg tttaatatag gaggccttag cttcacctgt
    27541 tatccagtcc tctaagatag caagattagt cctgataatg gcttgattgc gctgcaatag
    27601 cttgtcagca tgcttcaagg ctagtgaagc caccatatca tcaaaaacac ccgcacaaat
    27661 cattgtgtaa tctcgatata gtctaagctg atcacagatg gtctcggagg cagccaccca
    27721 gccaacccga atgcccggaa tcgaaaaggt ttttgacatg ctattaacag taatcccctt
    27781 atcatacaaa tctgccaccg ctaaaagatg atcagaggca aaggaatgat aaacctcatc
    27841 acttagtagg taaatatcat gctctctagc aatattgatg agctcctcta aatagagttt
    27901 ggtcatatag gcacctgttg ggttgttggc attgttgatc atgatcattt ttgtgttggg
    27961 acgaatcatg gcgcctagct cattaaggtc tggcagccaa gcctgctcct ctctgatctg
    28021 ccaataatca acctccactc caagagaagc tggaatatca tatagctgct gatagctagg
    28081 atagtgagca atcacatgat cacctgcttc aagcagtgca taaataacca aaaaattggc
    28141 acctgttgcc ccattggttt gcaagatatt tctagctttc tgctgctgat aaagccctgc
    28201 cactgcctgc ttaaagtcag gagagccttc tatccagcca tagtctaatg gcttttgatg
    28261 cagctgctgg taaaaggctt gaggctgctc ctgtgttaaa tcaaagagct cctcaagcgt
    28321 taatgaagca atagacgagc cagcaatatc atatacagca cttttttcat gctgatttag
    28381 ccactcttct acaccaaatg ccggtagttt cataagatca ccttatttct tgtgtaatat
    28441 ttattacaat atcgcataaa aatacaattg tcaagtcaga aactatcctt tgttgataag
    28501 aatcatgtcc tatctaacag ttagtcctga ttggtctcgc atgaaaggct actaaataga
    28561 gcaaaaatca cataaaaaga ctcccaaccc accaatcagc gggattagga gcctgatagc
    28621 tcgtatcaat tcattgattt cagatcagag tgactatcat cactctacta tgagccaatg
    28681 actaggctag gcggacaacc tctagctgtg gtccacccat taataccaaa tatttttcga
    28741 cctttgcaat cccataggat tggctcaaag cctcggcata caggtccatt tgctgctgat
    28801 accgctgctt cagctcagct gaatgctgat aatgatctgt cttatagtca aaaagaacaa
    28861 tacgatcctc aaaaagcagg tagccatcaa taataccacg cactacgtac tgctcctgac
    28921 ttaggctgtc ttttttcagc atcgcaaaag gagcctcgcg atgtagacac tggtgatgct
    28981 cttgcaggag ctgccccaat tcagttgtcg caaaaaaaga ggttaccttt ttaatatcaa
    29041 ttcttgcctt gacctctgcg tcagccgaga caaactgtaa ggcctgttca atatcaccag
    29101 cagtaacctg atcagacatt ggaatacgct gcatgagctc atgcaggctt gagccgatct
    29161 ggctaggctc aacagccttt ttcttagaaa aatcagggag atcaaaggac ttgggcctat
    29221 gataaggctg atctatgata tcaacaccat cagtatccat tagaggctca taaagggttt
    29281 taagctgact aggggttctc accgtcggca gctcaatggc cgcctgatag cttgcattga
    29341 gctctgacac cttatccagc atgtctaagg cacgcgcaat gtcctctgtt tgacggttgt
    29401 ccttgagatc atctgcttgc agcagccctg agggccttag ctgaccaaca gcttctggtg
    29461 ttaagtcact gtcatcaaca aatcgcacat caataaacaa gtcctccttg ctaaatgttg
    29521 ctactatcgc tagcagccag tcttgaaagc tcagcaatct ttctcgacta gctaaggcta
    29581 agcgtccttc ggagctattg tcggctgttt tttcctgtac cttttccttg ctagccttac
    29641 caatgaggta tacctttttt tctgctcgcg tcatggccac atacaagaga cgcatttgct
    29701 ctgatagggt cgccaagcgt agctgctgct tattgagctg gtaaggaaga gtttccatcg
    29761 taaccttgag cgacgccaat ttttcttctc ttagaagctc ctttacattg gcgacatatt
    29821 tgataccgat tccctcatct ctatttagaa tgattggtgc ttgtaggtca gccagcgcaa
    29881 agcgcttgtc gcaattcaaa atgaacacgt aatgaaattc aagtcccttt gatttatgaa
    29941 ttgtcatgag gttaacagcg tgcttaggcc tttcgacctc aacatctgcc aaatcatttt
    30001 gcatctccag caccttatca atcatgccaa taaagcgtga gagtcccttg tagcctgatt
    30061 gctcaaattg gtcagcccgt atagcaaggg cgtaaaggtt tgtctgagcc tgctctgcct
    30121 ttggctggct tgctacaaag tcaaagtaaa agcgatcgtt aaaaatcttc caaatcagct
    30181 cgtaaagcga atgaagcttt gcaaattgcc gccagtctct caaggttcca tcaaaatcag
    30241 ccagctttgt catcagctcc tgaccgatca gctctgggtg ctcgccttgt cctctcaagc
    30301 tattgctaag cttgtcatag aaggcttgag gctgcttttg tgagctgcct tgcagtgaga
    30361 ttcttgccag ctgatcctca tcaaaggaaa acattggtga gcgcattaag gccactaggg
    30421 cataatcatt caaaggattg ttgatgcttc ttagcgtatc cagcatgacc atcacctcaa
    30481 ctgatttgag gtaattttct tggccaccat cagcaacgag aggaatgcca tactggttaa
    30541 agacctgaaa aatagtgtca tttcgtgtgc gtgacgaaac aagcagggta atatcctcaa
    30601 aagcaacctt ctcctcgtta tagagcctaa tgatttcctt agccactaag gtgacctcac
    30661 ctgcggagat accatcatta gtcgatgctt cttcggtgcc ttcttgagct tgatcagtgt
    30721 tatagagcag caattgggcc cgattttcag ggtgtagctg cttttgtgcc tcactgcccg
    30781 ctaccagctg gtgcttgtca tcataggtaa tctctcctaa agactcgtcc atgagacgac
    30841 taaagacagc gttggtgaca ttgagaactt ctgactgact gcgaaagttt tcctttaata
    30901 aaatcagctt gccatgctca ggattgcttt gataatcctt aaacttttga ttgaagattt
    30961 gaggatctgc ttgcctaaag cgatagatgg attgcttgat atctccaacc ataaaacgat
    31021 tatggccatt agacaacagc tctaataggc gctcctgcat gtgattgtta tcctggtatt
    31081 catcaaccat gacctcatga taatgacctt ggtaagcttg gcgaatatct ggagcctgct
    31141 gtaaaatctc gatggcaaaa tgagctatat ctgaaaattc aaaggcattt tcttgcattt
    31201 ttgcggccaa ataggcctct gaaaagctga tcacaaaggc ttgcagcacc tccaaaagtg
    31261 gtaggctctc ctgctgataa gcaaggatag tctccaagtg cctaaatcct accagctgct
    31321 cctgtagcga tttaaaaata gggtatttgt gaccggccac agttatgtca gctcctgaag
    31381 gaagcaaggc tgttagctcc tgtgctagct ggcctagtcg cgctttacca taaaggctgt
    31441 caaaatgcaa agcccactca tataagctgt caatcatttt gaggtgcttg gtgtatttgg
    31501 cagttagctt gccagccttg gttgtttgag cgtaaccctc catgtctgtg aggtctcgca
    31561 gctgatcagc agtgtcctgc atacaggcta agagaatgtc tacagcttgg tctggaatat
    31621 ctgcaaagct ggtataggtc ttagaccctc gtaaaaagac ctctgccaac caactgctag
    31681 gattggcagt tgattgactg aaggcataaa tgctatcaac aatctctcta aaggctgagc
    31741 tatccttacg acgtccagaa aaattctgca ccagctgtat aaaggcttta ttgtcagtct
    31801 gcgacatata gtcttcaaaa acctgacgaa agacctcgcg ctttaaaatg tcctgctctg
    31861 ccttatcctg tatgatacga aaatgcggtg aaatccctaa aacataacca tgctggtgaa
    31921 ccaatttctg agcaaaggca tccatcgtac caatatcagc ctgtgataaa gcctgcaatt
    31981 ggtcattaag gtaggccttg agctgataat cctgagtctc tgctatagct gtgtgcagct
    32041 ttttttcaat tctctctatt agctcagtag ctgcttttac ggtaaaggtc gaaataaata
    32101 agcgatcaac cggaatacct cttagaatct tatccaaaat gcgctcaacc ataacaaagg
    32161 tcttacctga gccagcagat gctgatacta agatattttg tccactgcta taaatagcct
    32221 caatctgctg cgctgtccgc ttatgcgtct tatctgataa ggcctcctcc tgctgcaaac
    32281 gagcaatagc ctctggcgtt agaaagcctt catcaatcct catgctttat ctcctcattc
    32341 attcgtgtca agaaagcctg tctcctttct tttgtcggta ggacgactag gcgtctcgcg
    32401 taccctagat ctaaatccgc ctcaaagcgc gtgatggcct tgagctggtc accctgaaca
    32461 gacttgccgt ctgcggtata agggtttatt aggaaatgcc ctgttttaat ctgcttcacc
    32521 gcagacaaat atagctgctc attataagcc agcagggttt ctagctcatc agtctcataa
    32581 agtgtgttgt taaggtgata gctgccatta gccagatatt ccttggcttg ggctaaaaaa
    32641 atacccttat aggttaattc cttgtaagcc gcagctacta gctgatcatc aagtgcctta
    32701 aagtcagaca gacttagcct tggctcttgc atgtgcaggt acatggcgcc aaacaggccc
    32761 tgccccttat tctttagggc agcaagatag gtcacaagct gaggactcaa gccattgtaa
    32821 aaggcaccaa tgtcaaatac ccttgcactg gatttgtagt ccacaatgcc cagcctacca
    32881 tcagctagct ggtcaatacg gtcaataacc cctcgaataa gcgcctgatg acccagcgcc
    32941 agctcaaagg cttcctcttg cttggccacc tgcatgcctt gattaaggtc taagacagag
    33001 gctgttgagt aagcaatccc ctttaggacc tctaagctat atcgcccttc agcatcagcc
    33061 tgataaacct gctgaaaagc gctttgctga ttaactgctg caatagctgc gcctagcttt
    33121 ttatcaaagg cagcatcagt cctatcctta gtcaccagct caaaaatacg gtgcaggtat
    33181 tgaccatgaa tgcgagcatc tggatgaata gactccggct cttgcagccc taggacatat
    33241 ttcaagaaat acttgtattg attgttataa aatacagtca aagctgatga ggataggctc
    33301 aaaggctgat gactcggaaa gcgggtctcg ataacctcag gcgctactgg cttagtaacc
    33361 agatgatgct caggagctgg aagacttaac tgctcattgg ctagtctgcg cttcagataa
    33421 cgaagagcaa ccgtccaaaa gtttctatcc tcatcggtca tctcatctgc aatgccctgc
    33481 cgattaatag ccaccaagcg agacaagaga gccttatagt taccaatatc tgctgctgaa
    33541 tgtgacaaac ggttcttccc tttttcaatg acggaaacac caagggcaat cagctccttc
    33601 aggtaaggag agacatcatc tgagccattc gttgagcttg taggcaggct tagcaccagc
    33661 tcctgcgtcg ctgaattaaa cagagaaagt gctgtttggt gatttttctt gatattttca
    33721 aagctcggca catcaaggcg ttggtaagag gcagtctgct cattgatgct tgctctttcc
    33781 tgatcagaga tgagactggt gttttttgtc tgcttaggaa aatgagagcg actcaggcca
    33841 atcgcaaaca caaagggctt ggaatgcggc tccaccagat cataggattt gatagacaca
    33901 acatctaggg tcgcaggcac tgtccgatag tgtgctgtct gcatgcccat cttgattaga
    33961 gctaaacagt ctgcaagggt cattttttcc tgaccaaaca cctgataaaa ggtctctaaa
    34021 atacctgtga aggtcttcca aacctcctcg tccttttccc tgtcagcttc tcttctactg
    34081 cctgctagtg cctcaaaatt gtcagccagc tgaatggtct taaaaaaggt cattagctta
    34141 tcaagcagag aagcccctag ctgcttttga ctcttaaaaa gctgctggag cggggttacc
    34201 acagcaagcc gtagctgatt caaaaggggc aagggatact gacgtgagga atttagggta
    34261 aagggtcttg aaaatttggt gaagccttga atatcagcaa aggtcaagta ctgctcaagc
    34321 tgatccagct ctccctcttg aaagcgccca aagagtcctg attttagtaa gttaacaata
    34381 tcctcacgtc gccaattgta tctgcgacct ctttctaagg attcgacaaa ttgaaccaag
    34441 ggatgagcag acatgggctc ttgcttgccg atataataag ggatctcaaa tttctcaaaa
    34501 ataggaccaa tctgtagctg ataagacgcc acatcaccta aaaggacaag catgtcctta
    34561 tagcgataac cctgatagag cttctcacga atggcctttg caacatgctc aagctcctct
    34621 ttttgattga gcgcttgcca gatcacaacc ctgctcttgt ccttggcgct gagctgccaa
    34681 tcaagctgtg agtagtcatg attggcctca agaagctgtg tcaggcgaga aaatgacaca
    34741 tcaaagacct tttctgatgt cgtatagatc ggcttggttt gaaattgctg tgccagctgt
    34801 tggataaaag caaggctcgc ttcatagaga tttcccttgg taaaggctag tcgataagcc
    34861 ttttgactga tataggctcc aataacgatt tcttcacagg cttcgtttaa gagcgctagc
    34921 agcagctcct cctcagctga aaagcgggta aagccatcaa tcactaatac ggtctgcctt
    34981 agctcgtcat ctaggctctt gcttttgata gcctcagcaa gctgagccag cctacttgac
    35041 tgatcataat ccccttgagc aattaactgc tcagccttgg tcataatcgt gatcagatcc
    35101 tcttgttttt ctggcctatc aagcgtcgtt aagtcaaagg ctgtcagatt agctgcttgc
    35161 aattccttat atagctcaac taactgggca ataaaggcct gatctgtccg tagccggtga
    35221 aaaaccttta gctcatcttc ttgcagctgc atgagcacac gataaaaaat catggctaag
    35281 ccattatcat ctagcgcttg tcgattagct gccttggcta aggtaaaata acgcgccatc
    35341 tgctcaaagc gggtcaccgt aatagcaaag gaaccctgct ctggcaataa ggctaggaca
    35401 gaacgttcct tttcaaagga tagagagtta ggagcaatat aaaagacacg atagccctta
    35461 tcagcataag ctcttgcctc tttgactaaa atctctgtca tggaatagct aatctctgtg
    35521 tatagtaatt tcataaaact ccttttactt ggacctgata caacgtctac gtctccatta
    35581 taacaaatca gccttgcttt tcccattgtc aatactcctc taaacgctac aagaagcgct
    35641 cacagcatga aaaaagccta tcatttcacg tctgctgctt tgcgtgagaa atgtgataag
    35701 gcttcgtctt gtataggccc caaaaaacgg ctaggagctc ctagctaagc tgccttgtgt
    35761 ttgtctctgg tgatctgtcc ccaggcattc tttttacgct gataaccaat aaagctgctc
    35821 accttgacga gagttaatac cgtatgaaga acaaggcact ggtagatagc agcgtagatt
    35881 acccaaacca tatcaaaaaa agtaatgcta ctattgtttt gcgaataaat cctatttaaa
    35941 aacgatgtca gcgcaatcag cacacaatag caaatataga gcagcatcaa tgacacaaaa
    36001 aaggtcgtgt ttaattgatg gcatagtaaa gacagcacga tgatagtaac accaaaggtc
    36061 tcaataaagg gagataaaag ctcaaacaaa aggtacagca cataggatat gagtaccgtc
    36121 gccttaaacc gacagcttac aaaaaactgg agatactttt tcaagcattg atacagccct
    36181 aaaaaccaac gacgcctctg ctgacacaaa tcctttaagc gactgggcgc ttggctccag
    36241 caaatagcgt ctgtttcata gccgatacga taaggaatct tgttgttctg gcagaaaaaa
    36301 tgtaatttca tcaccagctc catatcctct cccagagtcc cagtgtcata accatcaaca
    36361 gcaatcgcaa gctccttttt aaacagtcca aacgctcctg atatgattaa attcccagca
    36421 gcctggtcta ataaaatgcg agctccaaaa aaagcacaat catactcaat tgcctgcgca
    36481 cacgaaatga gctgccgcgg caaatggtag tctacgatcc ttccagctgc caatgctact
    36541 ccctgcgaaa ccttaaccat gcccccaaca gcaatgacag acggatcctt tgcagcagtc
    36601 tttgcaatac gcttaagcga atcctcctgt agcatcgaat cagcgtccat gcacaagaaa
    36661 taatcgtatt gagcagcgtt aatcccaaga ttgaggctat ctcccttgcc gccattttcc
    36721 ttttcaagca gggtcagcct gacatgctcg agctgctttt gactcacagc ctttagagga
    36781 cgcgtcggga tccgctggtt gatagagcag gtcaccgctt ctaagtgaaa ccgttccttc
    36841 aagagcttgg cagtatgatc tgttgaccca tcatcaatga caataatctc atagcagcca
    36901 taatcaagca tcaacaagga ctccactgtt tcgataatgg ttagcgcttc attataggct
    36961 ggcaccaaaa tagacactgg cggtaaagag acatcatcac caagaggcac ttgctgtcgc
    37021 ctttcataaa gatgaatagc cccaacaatt agtgacagca ataaaaagct cgcataagca
    37081 atcaaaaacg ctaaaaaaag atactgggag tatttcaata ctaaaaacag tagctgcact
    37141 atcattctcc tttaacatgc aatcacttgt gcttaccatt cgcctgacaa aagcggctca
    37201 aggcctgctt catcaaatac ccaatgttaa agacaaggat tgctaagcaa acgattatat
    37261 aaaaaaacaa caagtaataa atcatctatt ttctcctctt ttcctgccag acagcctgca
    37321 cctgccgata ggaggtcttc aaaacctctc ttacccttgg acgctcccag ctcaacaatg
    37381 gatactctat cattgtaatg acctttgatt cctttagcgg ggcaaagcca atagctatcg
    37441 cctcaatggc taattcctca acaccatagt gctcaaaata atcatcgtgt attttgtttg
    37501 aagctggatc agaaaaattg agcagctgcc agggaatcct aagctcaatc agacgctctc
    37561 caaaggaaat atcggtctgc gaatcaaaat gagccgagcc tcgtttgcca ttgccctgtt
    37621 ttaattggcc ggtagggtag cgcttcagtc ctctttttgc gatcggaacc tgatcaatgg
    37681 ctgcaaaaat accatcattt ctcaccacca tatcaaccat agtaaatctt ggcgtatgct
    37741 tgttaggggg aaagacataa aagtcctttc cattaatctg cctaaggtaa ttggcatcag
    37801 tagcatggta gcgctcctgc accaagaggc gactgccttt gtggtcatca acaacaaggg
    37861 caaaatcagc aaagcgatca aaccgagcgc taaagccttc aataaccctg ctgcctgttt
    37921 tgggcgtaat gtctaaggga atgagccact gtctttgtaa gggctgcttt tttgtcgatt
    37981 caatagcaat atagaggtat ttttcgtcct gatcaacgag aagctgctgc ccatttttcc
    38041 tgtaggtcag agctctagac cactcacctg ctgccttttg tccgtcaata gcatgcgttc
    38101 tcggagcatg ctcaaaggtt aagagaccat agccttgagc cttagactga acatcacccc
    38161 aaagaaagcc ttgatgtcta ttggttgcaa aggaggtatt ccagctccta gcagtccaat
    38221 cgtcctgcca gctatggatc gttgcaccac agcagccaga cgcaataaag gctgtgtaat
    38281 ctgccatcaa gcgctcgcct tgatcctttt ctgtcaaagg gctggaagtc gatatcattt
    38341 ggtccacacc tctggctgtc gaatagccat agcccgtcac aaccactggg acacgatgat
    38401 agctcgtcag tagcttgacg tatccctgat ataagggcat gcgtttaata tccccaacaa
    38461 gcctatcatc aagccccaga cggtcaaata gcagataatc cctataagcc gagtgacaat
    38521 ccaagagctt ataggaagca aaaagaccgg ccttaacctt agcgctgggc ttaatatttt
    38581 caatcgtcag ttgaacatat tttgctgcct gagaggcaaa gggatcctga tagacaaagg
    38641 gatctgattg aggcgtattt gaaaagctca ccaagtgctg ccagccatat ttgcggctct
    38701 cgtatgacgt gatttcctcc atgatttcag ccagtatagc ctcaaaccga ttggcctgag
    38761 gtgtcgttgc ataatacctt cccttaaagc ctacaggctt ggcgtgattc tgatgattgg
    38821 tataggctat cgtcccactg tgccaatcat caccgacaat atagccgatc agccatttac
    38881 tcatatcctg gtcatagtgc tgaagcccta aatctgaatg ccagatccgt tttctcccat
    38941 gaatcacatc aacactggcc ctggcctctc ttaacagagt ccctaaataa gccttatcca
    39001 aggcgctgat agaagaattg tcatgataag catctattct aaagccctgt aatagataca
    39061 gagaatgact tgctgtgtca ttatagcggc tcaaggcatg gtaaaaagca gcaggcataa
    39121 taacccttac cctgatcgta ttggcaccca tagctgctat ttgcttgaac cacctgtaat
    39181 aggttttctc atcaacgcta aggtctcgtt gacgatagcc tgctatagag ctctccacat
    39241 caaccccctt gataagataa ggagaccctt tttggtcgta tatacgcttg tccttggcat
    39301 aaaagcttgt ccgaatagct gactggttag aaaccggcag gtacaagcga ccatcaatat
    39361 cacaacaata atagctcaag ccaatcacag acaagagcaa accaacaaag attaaatatt
    39421 tcttcatcac tacctactcc aataatgtat tggtattttt agacggtgca ctgtactgat
    39481 agagcgtctc aatatgctta tccagccatc gcccacgacg tctaataaag tcctttagtt
    39541 gcttaacaga ggcctcatag ctcctgtagt tacgactaac tggcacaagg taattagtgg
    39601 catcgcttct tgatggcact gtaaacacat agccccactt atgataattg cgctgaatag
    39661 ccggacctaa aaaagcaacc gtagcatcaa tatacttgat caaataatcc gttgataaaa
    39721 cattctgtcg gagctgatga taccttgtga ccaccagctt aacaaagcta ggatccttta
    39781 gtagcatgca aaaccaagga gcatctgata gggtaaagtc cgcctcatca taaggagcct
    39841 caatctgatt atcaaaggcg ttgttaaaat cccagaccac cagcttgagc ttatcgcgca
    39901 aatccttata aagataggtt gaaaacttcc cagcatcaat atttctaaag aattcattga
    39961 taataaaata gtctgcaaag gactcttgat ccagataatc agtgtattgc tttaaatcat
    40021 aagaatatag gagcttttcg atatgactga tgtccttttc aataaactgc ttttgcttgg
    40081 gcgtcagacg gtgcaggctt gggtatttaa tgtctaaaga ggacaggcct gcttgattcg
    40141 tataggatac gtaatgatca agagcctgct tagccttgtg tcttctatcc caaacaagga
    40201 tataaggcgt tttatcagat tttctatcac ttttttcgat gtttacccta tgccgcccct
    40261 gctcaatact ctccacagcc aagtacagac cacaatactg atgatccacc actaactcgc
    40321 aatacctgac gttaggtgca taggtcatga tctcaccggc aatattgtag ctaagataat
    40381 ttcggactag ggtccgatct aaaaaaggac catgcagcac ccactcagac tccttggaca
    40441 tgccagccag cgagactgcc tttggcttag cgcttttatt gataaacctt agctttaagg
    40501 atttcttgtc aaaatgacgt gacgaattgc ccctataagc aatcaatgct gtcaaggaca
    40561 agcgcggaga ctcagacagg ctgtgctctc tatctagctg atcacgaagc gagaccgtcg
    40621 ttttaatggt tttttgccgc tttgtctctc cctcgtattc cctttgctct ggaatctgct
    40681 gatgatgagt gtcaatgcta ataatcggca gatgagagct aaactcccca gtgcttctgg
    40741 agctcttttt gaccgtctgc aaatggtgat gaatacgctt tgcagaggtc ttaggaaaac
    40801 cgataccaca aatagcagct agcaagagac acaccagcac aatcacataa atcgtctttt
    40861 ctttcattta cgtcaaccag ttatgtcatc gctttgacta acaatattaa aataatcaac
    40921 tcgccccagc tgataaacag cctcagttaa cggattatcc tgctgatagg tgctgtcata
    40981 atcctttctt gacagctcaa agatcatctc aatatcatca gacgtggtgt ttttcacgcg
    41041 ctggatcgcc ttacccgaaa agtagttaaa cactaaccgc tccagctcaa tttccatttg
    41101 cttatcacag cggacaatca ataacagtct attgtcattt ctgacagctc ccataagcaa
    41161 caaaagcata aagatcacgc tactaccagt tgcagcgaca gtataatcac caacaccaca
    41221 gcaaatccca accacaatcg tccaaaaaat atagactgta tctctagagt ctttgatcgc
    41281 tgtccgaaaa cgcacaaccg acagcgcacc gaccatacca agagacaaag caacattatt
    41341 tccgataact gtcatgacgg ttgctgttaa gaccgtcaag gtcatcaagg aaacattaaa
    41401 cttcttgcta taggcagtcc cagtgtgggt ataggcatat gacatataaa tcacaatact
    41461 taacaaggct gcagcaacaa tatgcagcaa aacatcttga aagctcaagg ttccacgctg
    41521 ttcaaagaca tgtcttaata attgtttcat cttaatatct ctcctaaaaa cgataatgct
    41581 tgctgatagc tctccccatg caatacttgc ttgcacttag ctcgctacca ttaacagact
    41641 ccaacagctt cttgatatag gacaacaaaa agccattgta cttgacctcc aagatgacca
    41701 aatagggatc tagcaggtaa ttctgaggta gatgatctga aaaaatatca acattggtct
    41761 cagacccgat aatatgatga tcaaaggtaa tgcgaatatt gttttccttt gccacaaatg
    41821 ccttgcgctg gtattcgatt actgtttttg gctgatagag ttgcattgac atgcgactat
    41881 agcattcagc agcaaagcga tcaggataag ccagcaatat agacctgtct cccttgatca
    41941 acaattgagc gtctgctctg gttaacctca gggaccgctt tttttgatga ctcccttgct
    42001 tttgcttcat ctccaactta gcaaatgagc tctgactacc gtaattgcgc aggcgaattt
    42061 ttcgcctaag ctcaataccg tcctcttttt cctgccaatc aacgtcctcc aaagaatcaa
    42121 aatacaagga tcgaatcaca tacccctcac tagagctatg agcatctaga cgcaagagct
    42181 tggaaaattc atgcgataag cgataataat cctcaatggt aatcaaatac tttttttctt
    42241 gacgcaatac ctcattcacg ccagtgtcct cctttttcgt ctgtaagcaa tgccttaaca
    42301 ccaagctgcc cgtaacagca gccaacaaac ctgtctcata aataagacaa agccatcgag
    42361 atgattgttt actctacaag agtcaatcac ctaccaaaat agtaaatcct gccatctgtt
    42421 gaaataatat aaaccagctg atcgtcttga ttgcaagaca ggcgcttttg tgactgatct
    42481 agctgtctgc tgctaatatc agttgcatta gcctccttga gcatggcctg cttgagctgc
    42541 tgctggattt ttctggcttg cagctcagaa atctcaaagc tgccattaac cttttgagcc
    42601 ttgtgcttgt agaccagtgc cacatggtct ttagctgttg tcctagcagt cgacaggagc
    42661 ccttctttgt tgagctgagt atgctctcct acatcaatgg caacatagtc atagggtgcc
    42721 cgtatccggt gcgctgttag tattgaggac aaaatccccg tcacaaggca gatgcttatc
    42781 gtagccacta tcatctgctg ccgctgctta cgaatgaacc ttgaaaaagc acagacctcc
    42841 gcctgatatt cctgaagctc ttcttcaacc ttactataat cctgtctaag atcagccaag
    42901 tcaatctgac agtccttgca gcttgtcaga tgagcctcaa caaccgctct actataatca
    42961 ctcaacgtat catctacata taatggcaac aaatcctgga tcaactcaca atcatacttc
    43021 atagccatac tcctctcgta attgtctttt aatatgtttt cttgccctaa agacaagaac
    43081 cttggcagag gatactgtga tgccaatatc cttagctatt ttttcatagg aatctcccga
    43141 ataaatcctc gccagaaaga cagcctgcat tttctctgga agattaaaaa taatcgttag
    43201 tgtaatctct aacagctccc ttcttgctat cttatcaagt ggttcatcat gccctttagc
    43261 atcaacgatt tctaagcttt ccatcgacat attctcatat tttttctttt taatttctgt
    43321 aaagaaggtg ttctttgcaa tggtaaataa ccatgttttg attgaactat ccccacgaaa
    43381 tttagcaata ttacgataag cctttagaaa agtctcttga gtaatatcat ctgataaact
    43441 attttgataa cagcacagct tatttacaaa cctatagaca tcatctttat attctaaata
    43501 tatgtcctca aattccaaca gcttgtctcc tctcaataca cccttaatca ttagaccgtc
    43561 caatctgcca aaagttacag attaatttaa tttttagtat aagctgtcat caagtcagat
    43621 aaatagtaat gatctatcat cttattattg actcaaacga caaattatat tgcattttag
    43681 tataagctgt catcaagtca ggtaaataac aaggacatat catctaacat ttgatccaga
    43741 caaaaaagac ctgattctgt aatatacaga accaagtctt tctcaataga cattgactag
    43801 atgattgatt tatagcgaca tagctagata ggctatgact taccgtcttt tggatttgga
    43861 gacaagcccg ccaagacctg ccaagatacc actgccagca agagccaata aagcatctag
    43921 ctgactagtg cctgttttag ggagagtctt agctgagaac tgagaaacct ctccagcagt
    43981 ctgagcagca actaatttct cctgatgatg ggctgcttga tcagtccttg ctcctaaagt
    44041 ctccttatca gactgggacg ccctaagacg gataatggta gctgttaagc ctgatagctt
    44101 gaccccgtcc ttggttagca caaccccctc aggacttgcc agcgcctcag tgcctgcttg
    44161 cttggcatcg acgataacct caccagcaag aagagcctga aactcaccag ttagcctaat
    44221 ggtacggtca ttgctatcag cattgacaaa gacagcataa acatcaccat tgcttgctgt
    44281 tgtctgataa gcaatcacca aatcctgtgc cttgatccca tgctcatttg gaacagtgat
    44341 cagcttgacc ttctggtcta tctcagcctt acttgccaag cgaaaggcat ctgtcgaacg
    44401 gcgcagcgca atcaatccct tagtaaaggc ctgacttgtc gtgctttcag ggtagcgctc
    44461 tgtatccgtt gcctttgccc agtcaaaatg attaatggca tctgtcgaat cataggaatc
    44521 atgaataaag tatgggtatt caaatggtgt tccgtcctca ttgaccaaga ggtgtgattt
    44581 atttggcacc ttgtcatcag cgaccttgcc cttataggct tcgtccttaa attgctttgt
    44641 acgaccatat tcctgaccag catgtaggaa aggagtacct tgagaggtta gcaccaagag
    44701 attccctagg cgcaagcgac gatgaatctc tgccgcattt gctgcaacag atggatcctt
    44761 tttaatagac tgagcaataa tatcaaacag ggtcaggtta tcatgcgcag caatatattg
    44821 gatcacatca cctggatcat cagccaaaaa gttagtcggc tgagccttga tattgtgaaa
    44881 aatggtcatg atatccctag caccgcccgt aataaaggct ggagagcctt catttggaaa
    44941 gcctgatttg agctgattgc gaaaatcatc tgagaaggag gcaacagtgt ctgtctgtga
    45001 catccagctt tggtcggcag gctgctcagg catgtgctca tcaccctgat aggtgaccca
    45061 gccctcacca agcatgatga tattcggatt gagtgcctta gctgctaaaa aggctttttc
    45121 aatagctgct gcatcatggt cccccatcat gtcaaaacga aaaccatcaa ccttatactc
    45181 atccaccaga taagtaatcg aatccaccaa aacacgacga ctcatgtaat gcgttgtccc
    45241 aagtcgtcca ccaccaaatg aggtcctagc agtgccatca gcattcataa agtggtaata
    45301 atttggctcc aggtcctcaa aaatatcaac attagctgta tgattgtaga ccacatcaag
    45361 gatcaccccc ataccacgct tatggatttc attaacaagc tgcttaaatt cctcaatgcg
    45421 cttagctgga tcggtcggat cagtcgaata cataccagtc aaggcaaaat agctttgtgg
    45481 atcatagccc cagttgtaat tattatcact tgagctgtag gtcagcatac gctccttgtt
    45541 ggccaattcg ttgacaaaat aatagctcat cacaggcagc agctgaacat gcgtaatacc
    45601 aagctccttg agataatcca acttttcaac aaaggcagca aaggttccaa attgagcctt
    45661 taggtcatta gcaatcgcct gatctgaggt aaaatcacga acatgtgcct catagataat
    45721 ggcgtcctca cgcttatgaa agcccttaat atcagcaaag gccagctcct tatccccaat
    45781 agcagcagga tcaacaatgg ccgccttagc caccttatag gacggatctg tcttagcaag
    45841 ctcgctgttc catgccgcta gcgatttggc ataaggatcc aacacaagaa cagacttgcc
    45901 atctctagta atctcataat gatagaaata gcctctataa tctgaaatcc caagaccgct
    45961 atctgctgat agagtgattg accactctcc tttatcaccc tttgctagag caaagttacc
    46021 aatcaccttg gtctcatcag ccttatcata caaaacaagt gacaccttat cagcacttgg
    46081 tgaccaaatc gttagatcaa ccttggcccc tgcttctctc acacgcgctc ctagctcacc
    46141 gtcataagca tacaggctat ccttgtattg ccaatttggc ctagcctgga agctctcatg
    46201 atgaaaggtc accgtataag tggccactgc ttgactaaaa tcacctgtga tgacagcctt
    46261 atgagtcttt tcatctaagg tgatatcagt aatagcaact gcttccttac tgtcagtgct
    46321 gatttttaat tcttttaaaa ggctttcctt atccacatct gctagagtcg taaagctcgc
    46381 ctcaatactg cttgggctga cctgcttagc accgatcagt ctgacatgat taacaaaata
    46441 agggttcgtg taaatggttg gatcctcgtc tttcaagaaa atttgggtgt gattctttaa
    46501 atctttaaaa atataatcat tgggctgaat tttaacagcg tcacctgtct gacgctcatc
    46561 tagcaagaga aagcccagct cattaaagtc agctagcttg acatctatat aagcaccata
    46621 gcgaccgacc tgcttaaaat caataccatc tggccaagcg ccctgctgac tagtcattga
    46681 cgcatcagca cttccccaaa gccagagcga tttgttgtca taatggccat cactgcgata
    46741 ataattgata cggatatagc cctgagccag cggcgggtaa taagacagct cctggccatc
    46801 aatccagacc tcattcacct tagggctgat caattcgacc gtccgatccc ctgtgatatt
    46861 gtctcccttg gtattattaa tcaaaaagct aaccttatgc gcctgctcag ctgaaagctt
    46921 aacgtccatg taatagccat agtcatctgt cttcgctaga ctaaaattgg tagccccagt
    46981 cggccagcct cccagctgat cagatggtgt ctcaacatcg tcccacaccc aaagaccaag
    47041 cgaggatagg tcttgagctg gcagggtctt gaaatgcagc cgcagggtct gctctgctat
    47101 cggctcctct gagcttgtag cttctggtgt ctctagagag ctgtctgtcg taacaggcac
    47161 tatcgacgat gaaggctgag actggtctgt agtttcctca tgcgcctgat cctctacaag
    47221 aggtacagct actggctgaa cttccttgac agtatcagca ttgacagcag ctgacacctt
    47281 agtcacatca gaagttccag caatatcact aatgtcagta gcttctggta gctcatttga
    47341 gccttgctct tggtcggcag cccctgactt gaccatgacc gcaccatcaa taggctcaac
    47401 actcgtcaga ctctcagcag ctactgtagt atgcccacta gctgtcccca aagaaaaagc
    47461 ggctgcaata gctaccgaag ccactccaag cttaagctta cgaatgccaa ataattgacg
    47521 ctcttcaaac agcgcttgat tttcccttaa ccttttcatc attcctccgt ccttatcctg
    47581 atagttatta acaccttaag tatacaaaag aaatcacaat tgtgcaatcg ttttctttat
    47641 tgcaaataat gttatttatg aacaaatcag acaagattca gtgcaagcga tttccttact
    47701 gataaatacc tgctcccctc actaagacca gcccactgca aagcagaaaa gtagcctaaa
    47761 gagccttagt aacagataaa tgagcttaat gttgcttcat caactagctg gctgcaaccg
    47821 ttttgctctg atgtggtaac gccttgtcat catgactgag cttgacaaaa aaacgctgtt
    47881 agttacataa tcaatggtgc ttggtagcct tccattactc ctttgattgt tataccctat
    47941 atgatacaca aaacctcagt ttttatagta gaatattaca ctttgttttg acaaagatgt
    48001 ttaatcttgc taaaataaac ttatcaatga gggagtacca atgatgacat tcgaattcac
    48061 atcgttattc gatttacaaa ctgcttttcc aacagagcag gcttgtataa atcatttaga
    48121 aaatatcatt tggggtgacg tggtgatcag cccttttgat gctacctcaa aggtctataa
    48181 atgcaaggga aataaatacc gttgcaagaa tacagggaag tatttcactg tcaaaacagg
    48241 tactcttttt gataatacta agattaagct acaaaaatgg tttatggcaa tctggcttgt
    48301 gacttctcac aagagaggaa tctcctcagt gcaattatca aaagagattg cagtgacaca
    48361 aaaaacagca tggttcatgt tacagcgtat tcgtaaatgc tttggctctg aaaactgaga
    48421 tccacttggt gacgtcgttg aagtagataa aactgatatt gatggtaaaa ataagaacca
    48481 ccatgatcct aagaaggcaa aaacgttcaa gaaccatcct tctctgaaag ataagtcggc
    48541 agttattgga atggtgcaac aacaaagtaa ggccaacgct catacaatac ttgtgattac
    48601 tctgatagtc ggcgttttat cttttatcag ctaatgctga tatgcgaaca acttataagg
    48661 agctgatcaa tggttaaaca tgcaaaaact aacctacact ttgaattaga aagatctatc
    48721 tctcgcaaag ttgatagtaa attgatagcc tatcaagtca gtctttcaga tggcttttat
    48781 gacaaataca ccaaattatg ggataaaacc tattcatttg attttgtcat caaccatcgt
    48841 gcgttttatg ctcaattgac caaaagatgt gtttacgatg tccttttgca aactttggaa
    48901 aaaatcagta gaaaagccat tgcaaagcaa ctagcagagc ttgaagcctt ggttgatgtt
    48961 tcggaaagta aggaagactt tcagatattt ttcgagaaaa aatacaaact atcatttcct
    49021 gatttgaaga attgtgttta tccaaagaaa aaggaacttt ccgattttga tcaaaacctc
    49081 tggatagctc tacattataa ccctagaaag gagagggata cataatgaca acatggtatg
    49141 attacatggt aagagccagc gaacacgctg gaagtgatgg agacctctgg tttcgttatc
    49201 tttacaagat tatcaaagac ggagaaacca aactaactac tgatgatgtg gagcagttat
    49261 taaaaaatcc gaatctaact ccttttcaga aggtaactct gcaagatgct ttaacagaag
    49321 gtacgcatac aagagagcat gttttacagg caaaccgtaa aagtcagcca aaggatattt
    49381 tgaaactctt tagagaggga aactatggat aaaaaaatct tattcaaagc tctgaataca
    49441 gaactagcta aagaaaatat tagccttgac attatctgtg tcggtggttt tgtccttgaa
    49501 tattacaatc tgcgaggaac acaagatgtc gacgcctttt atcaagaaag tgttaacatc
    49561 aggcagatga tcaaaaaggt gggagatgag tttggcgtta atgaacctga tgagctttgg
    49621 cttaataatt cagttgccaa tcttaataga ataccaccta aaacgatttg tgagacagta
    49681 tttcactatt ctaacctgat tgtccttgtc ccacccttgt cttatattct tggaatgaag
    49741 ctagaaagcg gacgagatag ggatagacaa gatgccggag acattattaa gctagctaat
    49801 atccgttccc ctaaaaaact tatcaataca cttgaagagt atggttttca acctgatatt
    49861 tcaatgattt tagaagtctt tgaaatagct tatggcatgg aatggttagc aaactatatg
    49921 agcgaacacc cagaagaatt taggtattat taaaagacga tttctgtttg gaagtcgcct
    49981 tttttgaaaa caccttggga ttagtctaaa ctaatctcca taagcaaaaa acagcttagc
    50041 tccggctggg agtaagctgc ttttactgta atgtatgtga taattaggct aacatcaatc
    50101 attacaaaga gggaataaaa atttaatgtt tcttgcgttt gcgtgatacc acagctacac
    50161 ctaggcttgc caatacggca agggctgctg ctgtaaagaa tggagctgtt gcttctcctg
    50221 ttgacggaag cttgtgttcc attgctttag gtaccgctgg tttatctcct ttctgtgctt
    50281 ctggcttagg cattggctct ggcttaggca ttggcttagg cattggctct ggcttaggca
    50341 ttggctctgg cttaggcatt ggcttaggct ctggcattgg cttaggctct ggcattggct
    50401 taggctctgg cattggctta ggcttaggct taggcttagg cattggctct ggcttaggct
    50461 ctggcattgg ttctggtttt tctggcacta ggtagcctag ccatatcata tgaccacttg
    50521 aggttgagta aatatctagt aatgtcaact tgtctttctc aaaggtctta ttagctgttc
    50581 ctttttcaac aaatgccatt aggaattgcc agtccacatc tgttacaaaa cctggaattg
    50641 gcattttcag gaattctaaa acttcctcaa cagtctttaa gccacgaagc ttttctgtga
    50701 gctctcgacg ttgcttttta aggtcttcat ctttctttaa atcatcaccc tgaccttttt
    50761 cgtttggtaa ttctggagtc ttttcaggtt ttctaatatc attaccataa cctttttcat
    50821 ctggaagttt aggtaagtcc tcaggttttc caagatctct aatatcgtta ccatagcctt
    50881 tttcatttgg tagctgaggc gtatcttcca gtttttcttc gggtttagcg ttagacaggg
    50941 gaacttttgg tagatttgaa ctaatatcct tatctgcagc ggttttaata gtgatagtag
    51001 gagggctatc agctgagata gaggttggag agataaatac ccccattcct agcaagcagg
    51061 aaaccatgct aataggtagc ttctgcttac taagtctatg cctgtacccc gtttggtttg
    51121 ttagcatcgt tttgttatcg tcctttcctt actggctgag tctattgctg tgtgctttat
    51181 ctggagtaat catatatatt gtaaagagtt attatgacca attatcgaag gagtctgtcc
    51241 aataattaat ttcttctaga ccaattgaat cactatacat agtaaaagaa gtttctacac
    51301 tgcccttttt gatctcctga atatttactg ctttaccatt cacaataaca ttcaatttat
    51361 tcttgcttaa atgaccatat atctttaatg ctaacttgtt aacatctatc cttaaacggt
    51421 attttttgcc ttcttcaaat gttccgctat cttttttctt ccagccattt ccgtcctctt
    51481 cctcaaaaga aacctctgcc tgaagttgat tgaatacatt agtatctttc aatgttaaac
    51541 gcataccctc tgtagatacc tgatctccat ttttggggta tttaaaattt aaaaaatcga
    51601 attctacgct tgaaacctct acatcttcac tatttttatt actatccgcg acattgtttt
    51661 caaggttttc ctgtacctca gggtatttct taaaataatc ttcccattct tctttagcac
    51721 tggataaggt atataagtgc atacttaaag ctcccacatc ttcaccagta taacctgtta
    51781 aacgtatttt tccattacta tcttgtttaa ccgaatatct tatcaatcca actcttttat
    51841 tattgttagt ttttgcatct ctgtcatctg aatcagtaac ataaacagct tttactcttc
    51901 catcttctcc aatatccgct ccccacactg aaacaatatg accatatctt actaatgttc
    51961 tatacgataa tcctaatgcc ttgtgagatg ataaagcatt ttttatctct gttgaaaaat
    52021 catctattcc
//
LOCUS       DARYSY010000010        48700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYSY010000010 DARYSY010000000
VERSION     DARYSY010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48700
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            115..642
                     /locus_tag="TVR04_000478"
     CDS             115..642
                     /locus_tag="TVR04_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1269192.1"
                     /translation="MSVDDYRPTYAVAAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVVMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            642..1760
                     /gene="yqeH"
                     /locus_tag="TVR04_000479"
     CDS             642..1760
                     /gene="yqeH"
                     /locus_tag="TVR04_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1269193.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALAKGIEAREVYCQRCF
                     RLRHYNDITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1787..2095
                     /gene="yhbY"
                     /locus_tag="TVR04_000480"
     CDS             1787..2095
                     /gene="yhbY"
                     /locus_tag="TVR04_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1269194.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNRKLSVKVKSI
                     "
     gene            2179..2811
                     /locus_tag="TVR04_000481"
     CDS             2179..2811
                     /locus_tag="TVR04_000481"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1269195.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYINKEGLYQ"
     gene            2808..3401
                     /gene="yqeK"
                     /locus_tag="TVR04_000482"
     CDS             2808..3401
                     /gene="yqeK"
                     /locus_tag="TVR04_000482"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1269196.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLNPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3403..3756
                     /gene="rsfS"
                     /locus_tag="TVR04_000483"
     CDS             3403..3756
                     /gene="rsfS"
                     /locus_tag="TVR04_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1269197.1"
                     /translation="MRKEELLEIVIKGADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEAGGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3886..4629
                     /locus_tag="TVR04_000484"
     CDS             3886..4629
                     /locus_tag="TVR04_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1269198.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4739..5839
                     /locus_tag="TVR04_000485"
     CDS             4739..5839
                     /locus_tag="TVR04_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1269199.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRTQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIETLAFGTEQLLD
                     YQELSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPLLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHMDMPEQTWGRVPIRPGAMN"
     gene            6194..6910
                     /locus_tag="TVR04_000486"
     CDS             6194..6910
                     /locus_tag="TVR04_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1269200.1"
                     /translation="MKTVKEVSQLTGLSVRTLHYYDEIGLLPPTMVGENGYRFYDAAA
                     LRRLQDILLFRELAFPLKTIKQLLDSPSYDQQEALAAQIKMLELRKAHLEKVIAHART
                     LQKGGETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIF
                     SIFGRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDH
                     MGGAGTAAFVSRAISYYCQQ"
     gene            7051..7767
                     /locus_tag="TVR04_000487"
     CDS             7051..7767
                     /locus_tag="TVR04_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1269201.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            7989..8834
                     /locus_tag="TVR04_000488"
     CDS             7989..8834
                     /locus_tag="TVR04_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1269202.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSAKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9206..10051
                     /locus_tag="TVR04_000489"
     CDS             9206..10051
                     /locus_tag="TVR04_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1269203.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKKLIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10124..11494
                     /locus_tag="TVR04_000490"
     CDS             10124..11494
                     /locus_tag="TVR04_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1269204.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVALGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKKHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHS
                     KYGGVIESAAWYLLQVLSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATAKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAIRQLVAVAEPLYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSRDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11487..12551
                     /locus_tag="TVR04_000491"
     CDS             11487..12551
                     /locus_tag="TVR04_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1269205.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLSKAEREKKVAELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12552..13244
                     /locus_tag="TVR04_000492"
     CDS             12552..13244
                     /locus_tag="TVR04_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269206.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13289..14674)
                     /gene="brnQ"
                     /locus_tag="TVR04_000493"
     CDS             complement(13289..14674)
                     /gene="brnQ"
                     /locus_tag="TVR04_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1269207.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGGYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPVLYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDSLSYFFEKLVPLGQFSMGWISFSILGFVLGLII
                     SKAKAPHLTAS"
     gene            15102..16316
                     /gene="sstT"
                     /locus_tag="TVR04_000494"
     CDS             15102..16316
                     /gene="sstT"
                     /locus_tag="TVR04_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1269208.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16519..17193)
                     /locus_tag="TVR04_000495"
     CDS             complement(16519..17193)
                     /locus_tag="TVR04_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1269209.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17203..18579)
                     /locus_tag="TVR04_000496"
     CDS             complement(17203..18579)
                     /locus_tag="TVR04_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1269210.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTI
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALIIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKEFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19114..19827)
                     /gene="rsmG"
                     /locus_tag="TVR04_000497"
     CDS             complement(19114..19827)
                     /gene="rsmG"
                     /locus_tag="TVR04_000497"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1269211.1"
                     /translation="MTPQAFYLALEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            19964..20521
                     /locus_tag="TVR04_000498"
     CDS             19964..20521
                     /locus_tag="TVR04_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1269212.1"
                     /translation="MPMFLVILALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANYEEKTLEKITSLRSRVADATTPQATMAASNELSNQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLETFPSNLVAKC
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20553..21446
                     /gene="htpX"
                     /locus_tag="TVR04_000499"
     CDS             20553..21446
                     /gene="htpX"
                     /locus_tag="TVR04_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1269213.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGTIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPKVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDDDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVELTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21734..22267
                     /locus_tag="TVR04_000500"
     CDS             21734..22267
                     /locus_tag="TVR04_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1269214.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLMRDPQVIDIKNVRASGS
                     AQFDDGLYLLEYQLGYQITLPSSRSMTPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTETEKESQTLPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22453..23139
                     /gene="covR"
                     /locus_tag="TVR04_000501"
                     /gene_synonym="csrR"
     CDS             22453..23139
                     /gene="covR"
                     /locus_tag="TVR04_000501"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1269215.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23143..24633
                     /locus_tag="TVR04_000502"
     CDS             23143..24633
                     /locus_tag="TVR04_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1269216.1"
                     /translation="MAKQKKYKKTLPKRLSNLFFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERDI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAHEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24824..25318
                     /gene="nrdR"
                     /locus_tag="TVR04_000503"
     CDS             24824..25318
                     /gene="nrdR"
                     /locus_tag="TVR04_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1269217.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25302..26465
                     /locus_tag="TVR04_000504"
     CDS             25302..26465
                     /locus_tag="TVR04_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1269218.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKDLLL
                     TLARMNFLDEVINIMVLYTFNKTKSANIHKTYLMKMANDFAYQQILTAEAAIIKTRAF
                     GERKQQARSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26466..27374
                     /gene="dnaI"
                     /locus_tag="TVR04_000505"
     CDS             26466..27374
                     /gene="dnaI"
                     /locus_tag="TVR04_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1269219.1"
                     /translation="MEKIGKMVEHLGQTSRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERQKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPSAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQS"
     gene            27424..28734
                     /gene="der"
                     /locus_tag="TVR04_000506"
     CDS             27424..28734
                     /gene="der"
                     /locus_tag="TVR04_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1269220.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDPFPVSSVHGIGTGDVLDAII
                     DNLPVEEIVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPQLIKRISDSQSQRISSAVLNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29071..32163
                     /locus_tag="TVR04_000507"
     CDS             29071..32163
                     /locus_tag="TVR04_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1269221.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLQMNEDDTTKYRLLAFGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKIEGYYQIGKNYFESLSILQFDQASQDLIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKENRIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLLESPQLTVKREGGLLDISFDFSTVCQADIEKALATLFSDSSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELVVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTKTSKVLILAPSSLIYNWLDEFSKFAPQIDVAVSYGLKPARDALIREGHQVTIT
                     SYSSFRQDLETYQASDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEAKDVSRYIKPFVMRRKKEEVLPELPELIEMSY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDIHRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRTLLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKMLELQENKRHLITTVLDGNQGLASMSVEEIKEILGLQP
                     "
     gene            32367..32960
                     /locus_tag="TVR04_000508"
     CDS             32367..32960
                     /locus_tag="TVR04_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269222.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKAPVVSKESLHHSPAVDEDHSYAQKARRQAKQAVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAIKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33004..34335
                     /locus_tag="TVR04_000509"
     CDS             33004..34335
                     /locus_tag="TVR04_000509"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1269223.1"
                     /translation="MSKTYHFIGIKGAGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMAATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVRHHHKLIGQFHLPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREIDKGDVKVEDLAAK
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34383..34877
                     /locus_tag="TVR04_000510"
     CDS             34383..34877
                     /locus_tag="TVR04_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269224.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAKEVFKERTRLISDTF
                     LVAVIANQLVGYIEGPVVAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASQHGGSVWYQMLWQP
                     EEGY"
     gene            34974..36542
                     /gene="mltG"
                     /locus_tag="TVR04_000511"
     CDS             34974..36542
                     /gene="mltG"
                     /locus_tag="TVR04_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1269225.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASSDVAAVSQQTTSTAHTSATKLEETAV
                     AAEDQAVSSPEEPALSESLLKEEASVEGQTKKGGPVRRKVSKRQQTDRMAKKISTILI
                     SSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLIKN
                     STVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPEGY
                     TIKQIAKAIETNSRAKNRSKAKTPFRSKDFLNLVTSDAFIQEMAKKYPKLLGDLPSKE
                     VATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVLTL
                     ASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAIDT
                     TINSPYNVYTNTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTFEE
                     HSANVEKYVNSQIQ"
     gene            36615..37097
                     /gene="greA"
                     /locus_tag="TVR04_000512"
     CDS             36615..37097
                     /gene="greA"
                     /locus_tag="TVR04_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1269226.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37355..38275)
                     /gene="yidC"
                     /locus_tag="TVR04_000513"
     CDS             complement(37355..38275)
                     /gene="yidC"
                     /locus_tag="TVR04_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1269227.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQL
                     RKDVTAEKQALSTSKRTKSNRNAGKQKKRS"
     gene            complement(38358..38636)
                     /locus_tag="TVR04_000514"
     CDS             complement(38358..38636)
                     /locus_tag="TVR04_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1269228.1"
                     /translation="MKKVRLIISGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQANDPTKITRFIQKIRKGPSKWAKVTYVDVSPSHFEDFHDFRISN"
     gene            38928..39665
                     /locus_tag="TVR04_000515"
     CDS             38928..39665
                     /locus_tag="TVR04_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1269229.1"
                     /translation="MIITSKANRLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKFCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAANFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQAMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39704..40204
                     /locus_tag="TVR04_000516"
     CDS             39704..40204
                     /locus_tag="TVR04_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1269230.1"
                     /translation="MHYTEDIEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40224..40913
                     /locus_tag="TVR04_000517"
     CDS             40224..40913
                     /locus_tag="TVR04_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1269231.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIILDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQAGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41311..41553
                     /locus_tag="TVR04_000518"
     CDS             41311..41553
                     /locus_tag="TVR04_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1269232.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41733..42527
                     /gene="racE"
                     /locus_tag="TVR04_000519"
     CDS             41733..42527
                     /gene="racE"
                     /locus_tag="TVR04_000519"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1269233.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42524..43513
                     /locus_tag="TVR04_000520"
     CDS             42524..43513
                     /locus_tag="TVR04_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1269234.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAVLVTENER
                     LLAVHMPDDGVPVADFFGQQTGGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFEQKDRSAQFHTTLVVAAPDKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43489..44010
                     /locus_tag="TVR04_000521"
     CDS             43489..44010
                     /locus_tag="TVR04_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1269235.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKPYPSLSKEFKR"
     gene            44007..44468
                     /locus_tag="TVR04_000522"
     CDS             44007..44468
                     /locus_tag="TVR04_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1269236.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44465..45211
                     /gene="xerD"
                     /locus_tag="TVR04_000523"
     CDS             44465..45211
                     /gene="xerD"
                     /locus_tag="TVR04_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1269237.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQRVLADYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     RTLLPFLERAAEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45211..45918
                     /locus_tag="TVR04_000524"
     CDS             45211..45918
                     /locus_tag="TVR04_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1269238.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVDVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKHNHT
                     VIERDDYRIEDMMELIEARLELEQELALTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     VEQTSQFGHIVLRKEVQ"
     gene            45915..46454
                     /locus_tag="TVR04_000525"
     CDS             45915..46454
                     /locus_tag="TVR04_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1269239.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYEEDKESGLCLIESSRTYKLVTKECLAPLLRDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLIQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46700..47422
                     /locus_tag="TVR04_000526"
     CDS             46700..47422
                     /locus_tag="TVR04_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1269240.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKRGLVTLNGQVVTDLATTVKSG
                     DLVEIEGSPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEISQLHHLASTRK"
     gene            47419..47697
                     /gene="yidD"
                     /locus_tag="TVR04_000527"
     CDS             47419..47697
                     /gene="yidD"
                     /locus_tag="TVR04_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1269241.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLARLLRCHPFAAGGEDPVPDTFSLKRHFIKHEKIQDFDHKTD"
     gene            47856..48404
                     /locus_tag="TVR04_000528"
     CDS             47856..48404
                     /locus_tag="TVR04_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1269242.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT        13985 a         9059 c        11497 g        14159 t
ORIGIN      
        1 aaagcgtttg ctttgaaagg aggaacctgc tttcccttct ttttcatttg attttgaatg
       61 ctatttctgg tgaaatatgg taaaataaaa agtactaatt attttggaga tgaaatgagt
      121 gtcgatgatt ataggccgac ctatgcggta gcggctgttt atgatttaag agcaaatgat
      181 ttattgcgtc aagggattac ggctgtgttg gtggatttag ataatacctt aatcgcctgg
      241 gataatcctg atggaactcc ggaggttcgt gcttggttag atgagatgac gattgcagat
      301 attagtgtgg tggttgtgtc aaataacaca tattcacgtg tggagcgcgc tgtttcgcgg
      361 tttggtgttg attttattgc tcgtgccatg aagccttttg cctatggtat taataaggct
      421 attgatcgtt atggttttga tcgtgatgag gtcgttatgg tcggagatca gctaatgact
      481 gatattaggg ctagtcatcg ggcagggatt aagtctgttt tagtaaagcc tctggtaaca
      541 tcagatgctt ggaacactaa ggttaataga tggcgtgagc gtcgtgtttt ggcaaaatta
      601 gaagaaaaat atggaaggct agtatatcaa aaagggattt aatggaagaa ttattttgta
      661 tcggctgcgg tattcagatc caaacgacaa gaaagcaaga ggctggcttt acacctgctg
      721 ctgctttggc aaagggaatt gaagctaggg aggtttactg tcagcgctgc tttagattac
      781 gtcactacaa cgacattaca gatgttcaca tcactgatga tgagtttttg aggctgctcc
      841 atgaggtggg agatagtgat gccttggtcg ttaatgtgat tgacattttt gattttaatg
      901 gctcagttat tccaggctta tcacgctttg ttgctggaaa tgatgtgtta ttagttggga
      961 ataaaaagga tattcttccg aagtctgtta aggacagcaa ggtgacacag tggttgacag
     1021 aaagagctca tgaggagggc ttgagacctc ttgatgtcct gctgacgagt gcgcagaata
     1081 aatatgctat taaagagctg attgagcgga tcgatcaatt gcgccaaggg cgagatgtct
     1141 atgttgttgg ggtgactaat gttggaaagt cgaccttgat taatgccatt attcaggaaa
     1201 ttactgggga taaggatgtg attacaacgt cacgctttcc tgggaccact cttgataaaa
     1261 tcgaaattcc tttagatgat ggtagcttta tctttgatac tcctggtatt atccatcgtc
     1321 accagatggc tcactatttg tcagctaaga atttgaagtt tatcagccct aagaaggaaa
     1381 ttaagcctaa aacctaccaa ttaaatccgg agcaaacgct ttttttaggt ggcttggcgc
     1441 gatttgattt tattagtggt gaaagacaag gctttacagc ttattttgat aatcaattgc
     1501 tcctccatcg gacaaaatta gagggtgcag atgcttttta tgacaagcag gcagggcaac
     1561 tgctgactcc tcctgataaa aaggagcttg atgattttcc tcggttggtt cgtcatgaat
     1621 ttctgctgga tcaaaaagtg gacgttgttt tttctggtct tggttggatt cgtgttaatg
     1681 ctaataagga aactgcaact aaggtggcgg cttgggctcc tgatggtgtt gcagtagtcg
     1741 ttcgcaaggc gattatttaa taaataaaaa gaaaagtgga ataaaaatgc ttacaagtaa
     1801 acaaagagcc tttttaaagg ctgaggccca tagtcttaaa ccgattgttc agattggtaa
     1861 aaatggcttg aatgatcaga ttaaaaccag tattcgtcaa gccttggacg ctagagagct
     1921 gatcaaggtt actctgttgc aaaatactga tgaaacgatt catgaggtgg cagagatttt
     1981 agaagaggag attggctgtg acacggtttt aaagattggt cggatcctta ttttgtttaa
     2041 ggtgtcagct aaaaaagaca atcgcaagct atcagttaag gtcaaatcaa tctagcgaga
     2101 gcttttgcta ggctaagacg tttaggtctg ctgtgtcagt gctgacaaca tgagtaatgg
     2161 tgatattttg gagaggttat ggctttagaa cttttgacgc cttttacgag ggtggaatta
     2221 gaaatggaaa aaaaagatag taatcgcaag caggttggta tcttgggagg gaattttaat
     2281 cctgttcata atgctcattt agtggtggct gaccaggttc gtcaacaatt ggggcttgat
     2341 caggtgcttt tgatgcctga gtttaagcct ccgcatgttg accacaaaga aacaattgat
     2401 gaaaaacata ggcttcgtat gctggagctg gctattcagg agacagaagg tctagcgatt
     2461 gaagagattg agcttacacg tcaaggggtt agctatacct atgatacgat gaagctgtta
     2521 attgagcaaa atcctgacgt ggattattat ttcattattg gtgcggatat ggtagattat
     2581 ttgccaaagt ggcaccgtat tgatgagttg atccatatgg tgcagtttgt cggcgtgcaa
     2641 aggcctaagt acaaggctgg tacctcttat ccggttattt gggtagatgt ccccttgcta
     2701 gatatttcct caagcatgat tcgtgacttt atccaaagtg atcgtcagcc taatcattta
     2761 ttgccaaagg ctgttttaga ctacattaat aaagaaggcc tgtatcaatg atgtatcaag
     2821 attatgttgg ctataggcgt gatgagctgt taggaaaaat tgctgagcag atgagtgaca
     2881 agcgctttaa gcatgtcctt ggcgtggaaa gggctgctat tcacttggca gagcgttatc
     2941 attgtgatcc gattaaggct gggttagcag ctctgctgca tgactatgcc aaggaatgtc
     3001 ctgatgagct ttttataagc ttaattgata aatatcagct gaatcctgag cttcttaaat
     3061 ggaacaataa tatttggcat ggtatggttg gcatttataa gcttcaggaa gatttggggt
     3121 taaaagacaa aggcattttg cgggcaattg agattcatac tgttggcgct gctgagatga
     3181 cgatattgga taaaattctg tacgttgcag attatattga ggaaggtcga gtgtttcctt
     3241 tggtggacga agctaggaga atagcagagc ttgatctaga taaggcagtt gcctacgaaa
     3301 cagctcatac agttgcttat ttggcatcga aggctcagcc gatttttccg caaactattg
     3361 atacttacaa tgcctttgtg cattatttac atgaggaata aaatgagaaa agaagaactt
     3421 ttagaaattg tgattaaggg tgctgatgaa aagcgtgctg aggatatgct agctcttgat
     3481 ctggctggct taacaagcct aacggactat tttgttattg taacggcaac caatagtcgt
     3541 cagttggagg cgattgctga caatattcgt gaaagggtta aggaagcagg tggtgatgct
     3601 agtcatgttg aaggaaacag tcagactggt tgggtgctgc tggatttgaa tgatgtggtc
     3661 gtgcatatct tctcagaaga tgagcgttat cattataatc ttgaaaagct ttggcatgag
     3721 gctccagctg tggagcttag ccactattta ggataaaaaa gcagccggtt ctgggctgtt
     3781 ttttacaata agaaacagaa aggaagttgg cattaaaggc agagttgcct aagagataag
     3841 ctcttgtggt gcttgctgtg agatgtgctg actgtgccaa ataatatgca aaagaattat
     3901 gataccttcg catcagttta tgatgccatt atggacgact cgctttatga taagtggaca
     3961 gcgttttcgc ttcgtcattt acctaaaaac aaggagcatc agaagctttt ggagctggcc
     4021 tgtgggactg gtattcaatc ggttcgattt gctcagtcag gctttgaggt tactggcttg
     4081 gatcttagtc aggaaatgct agaggttgct aaaaagcgag ctcaatcagc taagaagatc
     4141 attacctttg tgcaaggcaa tatgctggat ctgtcacagg ttggatcgtt tgatgtggtg
     4201 acctgctatt cggattcgat ttgttatatg caggacgaga ttgaggtggg tgatgtcttt
     4261 aaagaggtct atcaggtttt gaatgatggc ggtattttta tgtttgatgt tcattctatt
     4321 tatcagatgg atcacctttt tcctggttat tcttaccatg aaaatgctga ggaatttgct
     4381 atggtttggg atacctacaa ggctgaggct ccacattcag tggtgcatga gctgaccttt
     4441 tttattcagg ctgaggacgg ccatttttta cgctttgatg aggtacatga ggagcgtacc
     4501 tatgatatct tgacctacga tattttgctg gagcaggctg gctttaagtc tttcaaggtt
     4561 tatgcagatt ttgaggatca ggagccaaca aagacaagta agcgctggtt ttttgttgca
     4621 caaaaatagc tgtggctaag acaggtcagc gagcggtttt gtggtttagt ggctctgtat
     4681 tgagtctgtg gcaggtcttg atgataatag gaatagacgc gaaaggtagg acaatgttat
     4741 gactgtcact ggtattattg ctgaatttaa cccttttcat tatgggcatc agtacttgct
     4801 atcacaggca aagggtctaa aaattgttgc gatgtcgggg aattttgtgc agcgaggaga
     4861 gccggcactt gtggataagt gggtacgcac gcaaatggca ttggaaaatg gagctgacct
     4921 tgtggtggag ctcccttttc tggtttctgt tcaatctgca gattattttg ctcagggagc
     4981 tgtggatatc ttgatgagac ttgggattga gacccttgcc tttgggactg agcaattgct
     5041 tgattaccag gagctgtcta ggctatatag tgaacaagca gaacacatga ctgcttattt
     5101 ggccacctta cctgatcatc tgtcttatcc acaaaaaaca caaagcatgt gggaggcctt
     5161 tgcaggcctt agcgctactg gtgataggcc aaaccatctt ttagcattat cctatgtcaa
     5221 ggccagcgca ggaaaaaagc tgcaattgca gccgattaag cggctggggg caggctttca
     5281 ttcagaagcc aaggatcaat gcttgtcatc agctacagcg attcgtaagc atatcgctga
     5341 cagagccttt gtggaaaaat catcacccaa tgcagctctt attttgaggg ctcctcaggt
     5401 gacctgggag cattattttc ctttgttaaa atatcacatt ctgacagctc cagatttaac
     5461 acagtttttt caagttaatg atgagctagc tagtagaatc agcgctgcta ttcggagcgt
     5521 agcgacggta gatgagctag tagaggcggt tgcaaccaag cactatacca aggcaagggt
     5581 gaggcgtgtg ttgacctata tcttggttaa ggctgtggaa gccccattgc cggaaggcat
     5641 tcatgttttg ggcttttcaa aaaaaggtca ggctcatctt aaaacaataa aagcttctgt
     5701 gccgctaatc agtcgtattg gagctaagcc ttgggatcag ttgactcaac gagctgacac
     5761 tgtttatcag ctggggcata tggatatgcc agaacagact tggggacgcg tgccgataag
     5821 gccaggggcg atgaattgag cgttactaga agcaaaccac tgtctttgta tgacacgctt
     5881 agaggaccag caagagcttc taagaagttc gggtaggcac tatagtcagt tggtaaaggt
     5941 gttgttagag tagttcaggt gactctttgc tggtataaag gtcagataga ctgcctttgc
     6001 ttgctaagct gtttttcatt gctgataaga agatagttag caagaactgt cagctcatgg
     6061 aagcttatca tttaagatca aaaaagttaa gtttattctt gactctctcc ctacgtgata
     6121 gtctatactt gttgttgagg tggaaatagc catactagtt ggagctcttc tgacctcact
     6181 aaggaggaat accatgaaaa ccgtaaaaga ggttagtcaa ttgacagggc ttagtgtacg
     6241 caccttgcat tattatgatg agataggcct gctgcctcct acaatggtgg gagaaaatgg
     6301 ttatcgcttt tatgacgctg ctgccttgag acgcctgcag gacatcttac tttttcgtga
     6361 gctggcattt cctctaaaaa cgattaaaca attgctggac agtcctagct atgaccagca
     6421 agaagccctt gctgctcaga ttaagatgct agagctacgc aaggctcatt tagaaaaggt
     6481 tattgctcat gctaggactt tacaaaaagg aggagaaacc atgacctttg acatttatag
     6541 taagtcacag ctagaagcct ttcaactaga ggctaaggag cgttggggag agacagaggc
     6601 ctatatggct tatgaggcca aagtcaatca gcctagcgca gagcagctta tcaaggatat
     6661 gggggagatc ttttcaatct ttggtcgtat gctggatcag cctgtagcag agctagcagt
     6721 acagcagcag gtaaaggctc tgcaggatta cattagtcaa cacttttacg attgctcaac
     6781 tgagatctta tcagctcttg gttgtatgta tcttgaggat gaccgcttta gagcggctat
     6841 tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc cgagctatta gctattattg
     6901 tcagcaataa gctgctaagt gcatatcact ggctgctatt cctaatttac gaaccctttt
     6961 gaaagtgcta taatgataga gttaaagcta atttaactct gcttattcta aaaagagctt
     7021 aatcaaaatt gtattttaga ggagaatcca atgggacgta aatgggcaaa tattgttgca
     7081 aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg ctaagtttgg tgttgaaatc
     7141 tatgtggctg ctaagcaagg agagcctgat cctgagttga atacagccct caagtttgtc
     7201 attgatcggg caaagcaggc acaggtgcca aagcatgtta ttgataaagc cattgataag
     7261 gcaaagggta atactgatga gacctttgtt gagggacgct atgagggctt tggaccaaat
     7321 gggtcaatga ttatcgtaga caccttgacg tcaaatgtga accgtacagc tgccaatgtt
     7381 cgtgctgcct atggtaaaaa tggcggtaat atgggagccg ctggatcagt ttcttactta
     7441 tttgataaaa agggggttat cgtttttaag ggcgatgacg cagacagtat ttttgagctg
     7501 ctcctagagg ctgatgttga tgttgatgat gtagaggcag aagacggatc aattactgtt
     7561 tatacagcac caacagatct gcataaggct attcttgctc ttcgtgaatc aggtatatca
     7621 gagtttcagg tgactgagct tgagatgatt cctcagtctg aggtaactct tgagggggat
     7681 gaccttgctg tttttgaaaa gctggttgat gcccttgaag cagatgatga tgtgcaaaag
     7741 gtctatcata atgtagctga tgtctaagcc ctaagactat cgtgtaaaca gagccgagat
     7801 ttctcggctc tgttcatttt cctataattg agctctgtag aggctgagta tgactatctg
     7861 tcttttatgg taacagctga cgtagtagct gattgtcaca tggtgttgct ttagtagagt
     7921 tcaatcatta gtatcttatg ataaaaaatg ataaactaat cttatgaatc ataaaggagt
     7981 agaggacaat gacaataaaa cgttatttag gtttagctgg cttggccgta ctgtctgtgg
     8041 gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc gagcacaaag gacacaccaa
     8101 aagaggttat ctttgcgaca gttggaacaa ctgccccctt ctcatttgaa aaggaaggac
     8161 aattgacagg ctatgacatc gaagtggcta aggctgtatt taaagatgct gagaagtaca
     8221 agcttcaatt taagaaaaca gaatggtcat ctatttttac gggcttagac tctggaaaat
     8281 atcaaatggg cggcaacaat atttcataca ctaaggaacg ctcagccaaa tatttgtttt
     8341 cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc aaaggatagt gatatcaagt
     8401 cttatgatga tattaagggt cattcaacac aggtggtgca gggaacaacg actgctgctc
     8461 agctaaaggc cttcaacgaa gagcatgctg ataatcctgt tgagctaaag tttaccaacg
     8521 aaaccatcac tcaaatgcta accaatctga atgagggcaa ggctgatttt aagatttttg
     8581 atgccccaac ggttaatgct atcattgata atcaaggctt agatcacttg aaaacaattg
     8641 agctggcaac aagcgagcag ccctttatct actttatttt tagtcaagat caagaggagc
     8701 tacaggcctt tgtcaataag cgcttagagg agctgacagc tgatggcaca ctcagtaaga
     8761 ttgccaaaaa gtatctaggt ggcgattatg ttccagctaa gcaggatttg aagcttccta
     8821 cagcaaaatc ctaaattggc tgaaagacca acaacgatat aagcgactat ttggcttaaa
     8881 accaagctgt tagaaggctt gcttttaagc ctttttaaat gcctttgttg cctactaggg
     8941 cttttaaagt aacctagtgt ctagggcagc agctattaag atctgttgcc ttatttcgag
     9001 ggtggttttg aggtaaaagg tctgtagtaa gagccttgac ttaattaatg cttgcttggc
     9061 tagtctatca gttggtttag gtttggtgtt ttgactagag attatagcta atggctatac
     9121 cttatcctaa aatttaccaa tttgaatgcg agagctattt cgtataaaat aaactcattg
     9181 aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa gctgtcggct ttgttagcct
     9241 tgctcttgct tcaatagctc tagtagcctg ctctggtaag caggacgaca aaaatacctt
     9301 gaccattggg gtaatgacta aaacggcatc tgatcaagcc agatgggata agattgaaga
     9361 gctgctgaaa aaggataaga tcactctaaa gtataaagag ttcacagatt attctcagcc
     9421 caacaaggca gttgctaatg gtgaggttga tatcaattca ttccagcact ataacttttt
     9481 ggataattgg aataaggaaa ataaggcaga tttgaaggct attgctgaaa cctatatcag
     9541 tccgattcat ctcttttcag ggactagtca agacggtaag gctaaatacc agtcagtaga
     9601 tgagcttcca gatggtgcgc aaattgcagt gccaaacgat gcaacaaatg aaagccgtgc
     9661 cctgtatgtg cttcaagcag ccggcttgat caagctcaat gtgtcaggtg ataagctggc
     9721 aaccattgca aatattacag aaaataagaa aaagctagat attaaagaat tagatgcgag
     9781 tcagacagca cgtgccttga cgtcagctga tgccgctatt gttaataata gctatgccgt
     9841 tcctgcgaaa attgatttta aaacctctct ttttaaggaa aaggctgatg agaatgccaa
     9901 gcaatggatt aatatcattg ccgcgcaaaa ggattgggaa aagtctgcta aggcagatgc
     9961 gattaaaaaa ttaatcaagg cctaccatac agatgctgtg aagaaggttg tggataaaac
    10021 ctcaaatggt gttgatgttc ctgtatggta aaggctagca caagagaaac aggaggattg
    10081 aggcgtgtga agcacgccct ttcttatatt aggggggaaa cacatgacaa aaacggatca
    10141 gcagtactta acaaggcttt gggaggatca gctcacacag gattatcttg tggcgttggg
    10201 gcaattgatt gccagtaggt ctatttttgc tcaaggtatc ggcttagaag agacagcagc
    10261 ctacctaaag gagctgtttg ctcaggctgg tgctgaggct attgttgata agacttatgc
    10321 agctcccttt gtcctagcac gctttaatag ctctaggcca gctgctaaga cactgatatt
    10381 ttacaatcat tacgatacag tgccagcaga tagtgatcaa aagtggacaa gcgatccctt
    10441 taccttaaca gagcgtgatg gctatttgtt tgcgcgcggt gttgatgatg ataaggggca
    10501 tatcattgcg agattgacgg ctgtcgtcag gtatctaaag aagcatgcag accttccgct
    10561 taatattgtc tttatgatgg agggagctga ggagtcagct tcggtagatt tagatcggta
    10621 tctggctaaa tacgcagacc agctaaaggg agcagagctt ttgatttggg agcagggcat
    10681 tcgtaatgag catgatcagc ttgaaataac tggcggcaat aaggggattt tgacctttga
    10741 gatgtcagta gatagtgctc gttgtgatat tcattctaaa tatggtggtg ttatcgagtc
    10801 agcagcctgg tatttgcttc aggtcctatc aagcttgcgg aaccatcgtg gggaattgct
    10861 ggtgcctggt atttatcaaa aagtcgttcc gccaactgag cgagagctag atttagttga
    10921 gacctatgca attgagaatg ctcaagctct aaaaaagctt tacggactgg agcttcctat
    10981 gttacaatca gagcgtcgtc aattgttagc agcttattac tttcagccct ccattaacat
    11041 tcaagggctg tggactggct atcaaggaca aggagttaag accatcattc cttcacaggc
    11101 tactgctaaa atggaggttc gtttggttcc tggcttagag cctgagtatg tctttgatca
    11161 gattaggtct tatttgctca ataagggctt tgaccagatc aagctgacct atactttggg
    11221 tgagatgagc tatcggagtg atctttcatc gtctgctatt cgtcagcttg ttgcagtggc
    11281 tgagccgctt tatcctaagg ggctatctct tttgccgaca tcggcaggaa caggccctat
    11341 gcatactgtt tttgaagccc tgcaggttcc gattgctgcc tttggcttag gacattctaa
    11401 tagtcgtgat catgcaggtg atgaaaacat tgctattgta gattattgtc ggcatattgc
    11461 attaatagag gagttaataa catcttatga gtgaaccaat gattcaatta gatcatattg
    11521 atattacctt tcaccaaaaa aaacgtgtga ttgaagccgt taaggatgta acgcttcata
    11581 tcaatcaagg agatatttat ggcattgttg gctattctgg tgccggtaaa tcaaccctag
    11641 tgcgtgtgat taacctgctg cagcagccaa caaagggaag cattacaatt gatggggagc
    11701 tgacctttga tcaaggtaag gttcagctgt ctgctaatag cctacgtgag aagcgtcgtg
    11761 atattggtat gatttttcag cattttaacc ttatggctca aaaaacagct aaggaaaatg
    11821 ttgcctttgc tctgcgccat tctcgattgt ctaaggctga aagagaaaaa aaggtagctg
    11881 agttattgga gctagttggc ttatctgagc gtgcagacaa ttatccagcc cagctgtctg
    11941 gtggtcaaaa gcagcgggtt gctattgcgc gtgcccttgc caatgaccct aaaatattga
    12001 tttctgacga ggccacttca gcgctggatc ctaaaacaac taagcagatt ctcgctcttt
    12061 tgcaggaatt aaaccgcagg ctaggcttaa cgattgtcat gattacgcat gaaatgcaga
    12121 ttgtcaagga tatttgtcat cgtgtggctg ttatgcagca gggaaccttg attgaagaag
    12181 gcagtgtttt ggatatcttc tcaaatccaa gagagccttt gacgcaggag tttatcaaga
    12241 cagcgactgg tattgatgag gcacttgaga aaattaacca gcaggatatt gtcaaggagc
    12301 taccagctaa tgctatttta gctcaactca agtatgcagg gacatcgact gacgagcctt
    12361 tacttaacca gatttatcgc cagtttgagg tgaccgctaa cattctttat gggaatattg
    12421 aaatcctaga tcaggtacca gttggtgaga tgattgttgt ttttgaaggt gcagcagcaa
    12481 gtattgaggc ggcagaaaaa gccttgcatg aggctggcgt cgatgtcact attttaaaga
    12541 gaggggctta aatgttagaa ttgtttcagg cttatttgcc aaatgtttat gagcttggct
    12601 ggtctggtga tgctggctgg ggagtagcca tttggaatac cttgtacatg acgatcgttc
    12661 catttattgt aggtggagct attggtttat ttattggtct tttgctggta ctgatggggc
    12721 cagatggggt gattgaaaat cgactggttt gttggctgct agataagctc acgtcgattt
    12781 ttcgggctat tccctttgtc atattgattg ctattttagc aagctttact tacctgatta
    12841 tgggaacaac cctgggggca acagcagctc tggtgccttt gacctttgct acctttccct
    12901 tttttgcgcg tcaggttcag gtcgtttttt cagagcttga tagaggtgtg attgaggctg
    12961 cacaggcttc aggagctacc ttctgggata ttgtcagggt ttatctgagt gagggcttac
    13021 cagacctgat tcgtgtgtca acagtgacct tgatttcctt ggttggtgag acagcgatgg
    13081 caggagctat tggtgctgga gggcttggta atgtcgcgat ttcctatggc tataaccgtt
    13141 ttaacaatga tgtgacatgg gttgccaccc ttattattct cttgctgatc tttgcgattc
    13201 aatttatcgg ggacagcttg acaaggcatt ttagccataa ataacaaaac tgctcagagc
    13261 tttattagct ccaagcagtt ttttaatgtc atgatgctgt aaggtgaggt gcttttgcct
    13321 tgctgataat aagacctaag acaaaaccta agatggaaaa gctaatccag cccattgaaa
    13381 attggccgag tggcaccaac ttttcaaaga aataggaaag actatcaggc aaggtaaaga
    13441 gcttggttag ctgcgatagg gtagctagag cgtcgtacag tgctggaatg atggtaagcc
    13501 caattgtcgt tctgtagaca agaggagcat tgccaaagga tttttggatc agaacaagga
    13561 caatcaaatc gacagtcagt ggatacaaga ggtacaaaac aggagatgac caattgataa
    13621 taactgacaa accaccgaag tagaaaaagg cagatacaag ggtaaataga gttgcccaag
    13681 caacatgtga tacccttggc attagcttgt ggaaatactc tgcacttgag gtgataagac
    13741 cggttgaggt ggtcagacag gctaggaaaa tcacaatcgc aaggaaggct tgcccaatgc
    13801 tacctaggta aaatcgtgag gcgtggctta aaatttgtcc tccattgaca gcactattgt
    13861 ttaaggtgaa atgcccatca acaaaaggaa aaagagattg tgaggtcgca ccgatccgtc
    13921 ccacaaaaat ataaacaaag gctagcagca aaatggcaat ggccccagag ataagggtga
    13981 ttttagtgat ttcctgatcg gttttagcgc caaattgctt ggttgcttca atgactaata
    14041 tggcaaaaac caaggaggct agagcatcca tagtaccata accttgaata agacctgcaa
    14101 tgaagggaac gtccttaaag gcattgttga taccggctcc agcattaaag gcctcgccat
    14161 aacctccagc tgggtgaaca aaggaggcaa tgattaaaat agtaatcaca accaatagcg
    14221 tcggtgtcag aaatttaccg atgctttcgg ctagcttgct tggtctaata gctaaaaagt
    14281 aggataagcc aaaaaatagc acagcataga tggctttatt gatgatgcta tctcctaata
    14341 tcggggcaat cccaacagag aaggaggtag cgcctgttct aggaatagca aagaaaggac
    14401 caatggataa atacaagatt gatgagtaaa ggatagcata ccattttgaa atcggccgag
    14461 ctaagctttc aacatcatca gagcccgatc ttgcaacagc aatgacacca agcaagggta
    14521 aagatacacc agtcaagcaa aagccaataa tagaccaagg gatattttgt cctgaataga
    14581 tgccaagaaa agccggataa atgagatttg ctgcaccaaa aaagagcgca aacagcataa
    14641 agccaataac gatatagaca tttttttctt tcattgcctt aataagtctt tcttttgata
    14701 taaatttgaa gattccaata atttaattga aaactcttga aaataataac agttgctatt
    14761 atacctaagt ttctgaaagt cgtcaacaat tatcagacgg tagattaagc tgagacctaa
    14821 aaaagcgctg aggatcatct ggataaagca gcttagcctt tattttacag cctttgagag
    14881 ggcttggtca gctgctaaat ctctaatcaa gtcttgctag aaagactgct ccaaggcttg
    14941 gggagctttg atgagagatt tgctgtctta ttgatgaaag aatctgtcag ctagcttatg
    15001 atggtggggc tgcagcggtg tataacatcc ttgcttgatt tgacgaataa ctaaaattat
    15061 attatgataa aaaacatcta acttgagcga ggataaataa catgaaaaga attcgtgact
    15121 tatgggtcag gaccaacctg attaaaaaaa taggaatcgg ggtcgttata ggacttcttt
    15181 tggggatttt attgcctgat gtgacagcga ttggcatttt ggggcagctt tttgttgggg
    15241 ctttaaaggc gatagctcct ctcttggttt ttgccttggt ggcacaagct atctctcacc
    15301 aaaggtcagg acagcaaacc aatatgacct tgattattgt gctttatttg cttggaacct
    15361 ttctggcggc cttggttgct gttattgcta attacctatt tcctctaacc ttaaccttaa
    15421 atactccggt taatactgag ctttcaccac cacaaggtat tgttcaggtc tttcagacgc
    15481 ttttattaaa gctagtggat aatcctatta atgctttagc tactgccaat tatatcggtg
    15541 tcttagcttg ggcattgatc tttggcttag ccctcaagtc tgttccttca gattttaagc
    15601 atttgatcaa aacagcggca gatgtgacct cacaaattgt cgtttggatt atcaatgtcg
    15661 caccgattgg cattatgggc ttggtctttt caactgtttc tgaaaatggc attagcattt
    15721 tgtctgatta tgctctttta attctggtct tggtggggac catgctcttt gtagcgctag
    15781 tggttaaccc tttgcttgcc tttgtcctga ctcatcaaaa tccttatcct cttgttttta
    15841 gatgtttaaa ggattctggc cttacagcct ttttcacaag gagctcggca gcaaacattc
    15901 cagtcaattt gcagctatgt gaggacttgg gactaagtca ggcgacctat ttagtatcta
    15961 ttcccctagg tgcaatgatt aatatgggag gagcagccat cacgatcaat gttttgacac
    16021 ttgctgctgt caataccttt ggtattcaga ttgattttct gactgccctg cttttgagtg
    16081 tggttgcggc tatctcagcc tgtggcgctt ctggtgttac aggaggctct ctccttctta
    16141 ttccagtggc atgtagcctt tttgggatct caagtgattt ggctatgcag gttgttgggg
    16201 ttggctttat tgttggtgtg attcaggatt cctgtgaaac agccctcaat tcatcgactg
    16261 atgtcctctt tacagccatt gctgaaaatg ccttctggaa gcaaaagaag gcctagccgt
    16321 aatagccctg ttaatacagc ttattagtaa aaaaagaggc tgggacaaaa agagctgcac
    16381 tttagaaagt cttaacctaa tatactttat gacctagtct catgcattaa aaaagcgaac
    16441 aagtctagct ttcggaatct ctgaaagcta gacttgttcg tttattttag gtcagacttt
    16501 tgtcccagac ccgttatgtt atttgaggta gcctaggtag tcaaactttt caaaggtatg
    16561 atcgttggcg atagcaacaa taatggtgtc ggcctcaagt ggttcaaagg gctgaacatt
    16621 agtatctagg gttttcactt ctttttgacg catgccaata atattaagtt catattttcg
    16681 acgaacatca agctctgaga gcgatttgcc ttcccagctc ttaggaatag taaattcaat
    16741 catggaaatc ccatgctcta ggtagataat gctctcaatg tggtggcgta agagatttga
    16801 ggccactcgc tttccagagt ctctttcagg agtgatgacc ttggttgctc caatgccata
    16861 taaaacctct tcaaaaattt tgtttttagc ctttgcaata atggttggga cccctaattt
    16921 tttacagtgc atgacagcta gcacagagga ctctaaattg tttcctgaag caatgacaac
    16981 tgtgtcgcat tgctcaaccc ctactgcgat taaaaaatcc ttatcagtaa tatctccaac
    17041 agctgccttg gtcgccaaat cagcaatttc tttcacgtgg ctttctctaa tatcaatggc
    17101 aatgacatct tggtcgtaat tgcttaattc tctggcaacg gtgcggccaa aaatccctag
    17161 accaagaaca ccaacagttt ttcgttttaa catgatttct ccttaaccca ctaaaatatc
    17221 agtagtggca tattgaatgg ttttttcttt acgttgaatt agactaatca aaacagtaat
    17281 cggtccgaca cgaccaacaa acatcagcac aataatgatt aggcgtcctg cacttgataa
    17341 gtgcggtgtg acgtccattg ataccccaac tgttgcgatg gctgaaatgg attcaaataa
    17401 aagcggaata ggagcaatat ctggctccac gcttagcagt agaatgtagc caatcatcaa
    17461 gactgcaaaa aagaaaatca aaacagtcat ggtttgctta atggtcttgt tggcgatgat
    17521 acggttacga aaggttacct cagattgacc agaaagctct gccttaaaca ataaaaaggt
    17581 gatggcggca gttgtgattt tgattcctcc agcagtacca cctggagctc caccgatgac
    17641 catctgaatc atataaagaa tattggtagg agccaaggta tcattataag aaatagtcgc
    17701 aaagcctgcg gttctcatgg ttaccgtttg gaaaaaggac accatcagct gctgcggtag
    17761 attgtatctg gcaatagtat tgagattgtc cttttccaaa aaccatgata aaaaggtgcc
    17821 taaaacaagg ataactaggg ttgtttgcag cactaagcgt gactgattag aaaacttttt
    17881 aaaggtgatg ccatagcaat gaggcctttc aaagaagtat tttttaaagg cagtgcctaa
    17941 atcaacccaa acagcaaagc caagtccgcc agaaataatt aagaaggtga taatagcatt
    18001 gatggtaggg tttagcacaa actcctttag gctagatgat cctagattat caaagcctgc
    18061 attacaaaag gcagagacag ctaggaagat actgttaaaa ataccatttt tccagccgaa
    18121 gcgagggata aagtcagtca tgataatcaa ggcagcaaag gcctccagtg agaaggtgac
    18181 cttataggca aaaaagaggt atttttttaa gtccttactg tcaccacgat tgagggcgga
    18241 ttggagcaag gtttgatcac ttaaacgcat tttacgcttg agtgcaaagg tgctgaccgc
    18301 aatcagagtg accaatccaa gtccgccaat ttgcatgagc atcatggcaa ttgtctgacc
    18361 aatgccattg tagacatctg caacaggaac gacagaaagt ccagttacac agaccattga
    18421 caccacgttg aaaaaatgat caaggtaaat cgtattagga ccattgctgt agtgggtaaa
    18481 aggcatggat aacaagagac tgcctatcaa aatgacaatc gcaaagctaa aggttagccg
    18541 ctgggtcacc gataaggact tgaaaaatga gcgtttcatg attcctccta ataatatctc
    18601 atactatcat atcaaaaata cattgaaaaa gctaagcagt aacctagctt tagactgaag
    18661 cagcccctgt ttacgataat accttcctaa catgctccaa aggacaatag ctttctttga
    18721 catgtcaggc ttaagctttt agtttagaac ttaaaagtgc tgagtgagat tttctaaagt
    18781 cttaagggct ttagtcattg ttgccacagt agaaagcaga atggtgagct cactgcctag
    18841 cctatgcttt ttcttgctag gcttcaaaga ggcttgatgt tttgaagcgt caaaagtaat
    18901 cttgacaggg ttctatatgg ctaatcgata tcactcaagg ctagcactta gcttttgtgg
    18961 tttgatcaca tgatcattgg ctgtggtcat agcgtcagct ccctcctact agcctctaat
    19021 ggctaatagg agggagctag tccatcaagg gcaacaaaaa acgtttcaga cagcctttaa
    19081 tcaaggctgc ctgaagcagc attctatagc ctcttacaat ggttttttat taggaatacc
    19141 ggcttttcga gggtacttgt ttggcgtttc ctttttcttt tcgacaagag tgatatagcg
    19201 gccatctcca ttagggagct gatagggctg gtgatcaagc actttagcaa agagtagctg
    19261 aagtgccttt ttagcttctt ctaattcttg gtccgctgct tgtgccttta aagcaatcag
    19321 ttttcccttg atttttaaaa aaggaatggt caattcagac aggatctgca tgcgggcaac
    19381 agctctagca gttaccaaat caaattgacc acgaaattgc ttgtcttgtc caaaatcctc
    19441 tgccctacca tgatagaaat gcaccccctc taatcctagc tctttagcaa ggagctgaag
    19501 aaaatgtata cgcttattga gagaatcaat aatggtaaca tcaagctttg ggaacataat
    19561 tttcatagga atgcttggaa agcccgctcc agccccaata tctaacagcc tgagaggctc
    19621 gtttggaatg tatccctgta aaagtggagc aacagagtca taaaagtgct tgagatagac
    19681 ctcattttct tcagtgatgg ctgttaggtt gatcttacga ttccaatcaa ccagaagctt
    19741 aaaataagtg tcgaattgtt ctttttgatg atttgtcaga gcaaatcctg cttgctctag
    19801 ggcaaggtaa aaggcttggg gtgtcatata tatcctctat attttaatta attgctacta
    19861 ttttagcata aaatagcaga aaactgctga aaagcccctt caatacttgc tattaaactg
    19921 aaaattgcta taattgagac acaaagatta aaggagaatt gcaatgccaa tgtttttagt
    19981 aatattagcc cttatcggtg tgctggttgt ttggctgatg gttagctata atggcttggt
    20041 taaagctcgt atgcatacaa aggaagcttg gagtcagatt gacgtgcagc taaagcgtcg
    20101 caatgacctg attccgaacc ttgttgagac ggtcaagggc tatgccaact atgaggagaa
    20161 aaccttagaa aagattacta gtctcagatc acgtgtggct gacgctacta caccacaggc
    20221 cacaatggca gcctctaatg aattgagcaa ccaggttact agcctatttg cagttgcaga
    20281 gagctatcca gatttaaagg ccaatagtaa tttcctaaaa ttacaagagg aattaaccaa
    20341 tacagaaaat aaaatttctt attcgcgtca attatttaat acaacaacgt cgcattataa
    20401 ccttaagcta gaaacctttc cgagcaatct tgtggccaaa tgctttggct tcaagccaag
    20461 tgagttttta caggttcctg aggctgaaaa agaggttcca aaggtagact ttacagttta
    20521 atgcggctaa tcaaggtcag aagaggacat caatgcttta tcaacaaatt tcacaaaata
    20581 aacgacgaac agttatcctg ctttttgcct tttttgtctt actggtagtg attggcgctg
    20641 ctgctggtta tttactggct gacagctatc agctgggggc tgcctttgct ctgattattg
    20701 gtactattta tgcctttagc atgatttttc agtcaaccag cctcgttatg ggaatgaata
    20761 aggctaagga aatcacagta aacgatgctc ctgatttctt tcatattgtt gaggatatgg
    20821 ctctggttgc tcagattcca atgccaaaag tatttatcat tgatgatccc tcactaaatg
    20881 cctttgccac aggctccagc cctcaaaatg cagctgttgc ggcaaccact ggtctactaa
    20941 aggtgatgaa tcgtgaggag ttagaagcag tgattgggca tgaagtcagc catattcgta
    21001 attatgatat tcggatatcc actattgcag ttgctttagc tagtgctgtc acactgattt
    21061 ccagcattgg ggggcgtatg atgtggtata gcggtggcag gaggcgtgat gacgatcgca
    21121 acgataatgg ctttggtgct attatgctga ttttctcaat cttgtcactg atcttggctc
    21181 ctcttgcggc ctctctggtt caattagcca tttctcgtca aagagagtat ctggcagatg
    21241 ccagctctgt cgagttaacc agaaatccag agggcatgat tagggctcta caaaagctaa
    21301 gcaattcaca gcctatgact catccagtag atgacgctag cgcagcctta tacatcaatg
    21361 agcctagaaa aaaagagaag cttagcgctt tatttagtac ccatccgccg attgaagata
    21421 gaattgaacg cttgaagcat atgtgagagc ttgagactag ctcagctctc atttttacta
    21481 gccataatgt tcagaaaaca tcattaatta attgttttga cccggacatt ttttaagact
    21541 tttatggaaa tttgggctat tttcataggg gatttatggt taaacatttg attgttggct
    21601 tgtcaatact tatttgtatc cagacttaat gttaaaaaaa gttatgaatt tgtcataaag
    21661 ctattgacaa attcttgata tcatagtaaa aatagattag agttttatta ggaagtgttt
    21721 tataggagaa agcatgttat ctgtttcaga tattagaaag cgaccggaag gcattcgctt
    21781 tgagagagag tacgatgtta aggaagcgct gcttatgcgt gatccgcagg ttatagatat
    21841 taagaacgtc agagcttcgg ggagcgctca gtttgatgac ggcttgtatc tattagagta
    21901 tcagctgggc tatcagatta ccctgccctc gagccgttcc atgacgcctg ttgtcttaga
    21961 tgagatgcag acggttcagg agctgtttat cgaggaagca gatgtggcaa gtaagcagga
    22021 aatggttgat gaaaatcttg tcttagtctt atcagaggat cagcttgacc ttgaagagag
    22081 tattattgac aatattttgt tggcgattcc cttgcaggta ttgacagaga ctgaaaagga
    22141 gtcacaaacc ttgccaacag gggaggattg ggcagtctta actgaggagc aataccaggc
    22201 tcagcagaag gaaaaagcaa aagacaacag tccttttgcg ggcttacagg gtctttttga
    22261 cgagtaaaaa caaaaaatta aagatgtctg tattttttat ttgaaaaaag aacagttgtc
    22321 tggtatactt tataaatata cggcatatta gtcattttga tgactaaata gcaatacttg
    22381 attaatataa aatggatgaa tcttgtacat agctgataag gggctgtgat acaggaagta
    22441 aggattggtg taatgacaaa gaaaatttta attatcgaag atgaaaagaa tcttgcaaga
    22501 tttgtttcgc ttgagctaca acatgagggt tacgaggtga ccgtcgaggt taatggtcgt
    22561 gagggcttgg agacagccct agagaaggac tttgacttaa tccttcttga tttgatgctt
    22621 cctgagatgg acggatttga agtgacacgt cgcttgcaaa cagaaaaaac gacttacatc
    22681 atgatgatga ctgcgcgtga ctctattatg gacgttgtag ccggcttgga tcgtggtgct
    22741 gatgattata tcgtgaagcc atttgccatt gaggaattgc tggcgcgtat tcgtgctatc
    22801 ttccgtcgtc aggacattga gtcagagaaa aagactccta gtcaaggcgt ttaccgcgac
    22861 ttagtcttaa accctcaaaa ccgctctgtc aatcgcggtg atgacgagat ttcactgact
    22921 aagcgtgaat atgacctgct taatattttg atgacaaaca tgaatcgtgt catgactcgt
    22981 gaggagctct tgtctaacgt ttggaaatat gacgaggctg ttgaaactaa cgttgttgat
    23041 gtttatattc gttaccttcg tgggaagatc gatatccctg ggaaagaatc ttacattcaa
    23101 actgttcgtg gaatgggtta tgtgattcgc gagaaataat tgatggcaaa acagaaaaaa
    23161 tataagaaaa cgttaccaaa acgtttatcg aatctttttt tcgttctctt cttttgcatt
    23221 ttctctgcct ttaccctact cgcttatatt tcgacaaact actttttgtt gaaacgagaa
    23281 aaacaaacta tttttcaggc tgttaacatt gttagagttc gtctttctga ggtggactct
    23341 aattttacgt tagagaattt agcagaggtt ctctataaaa acgatagaac gcatttaaag
    23401 attgatgacg caaatggtag tcgtattatc agaagtgaac gagatattac caatacgctc
    23461 aatgccaatg aggatatcta cgtctacaat gttgataagc aaatgatctt cacaacagat
    23521 gacgaagagg cctcgccagg cttaaatgga actattggta aggtaaccaa ggaccacatt
    23581 gaggagcaat acaagggctt ttcaatgacc cagaaggtct actctaataa gacagggaag
    23641 tttgtaggct atgttcaggt tttccatgac ttggaaaact actacatgat cagagcacgc
    23701 ctcttcttct ggcttttggt ggttgagctc tttggggttg gtctggcgta tttcattatc
    23761 ttaattgtca cacgcaactt cttgaagcct ctgaacaatc ttcatgatgt gatgcggaca
    23821 atttccaaaa atccagataa tctgatgctg cgctcgggta tttcctcggg tgatgaaatt
    23881 gaggaattgt ccgttatttt tgataaaatg cttgataaga ttgagacgca tacacgattg
    23941 caatcaagat ttattagtga cgtcagtcat gagctgcgca cgccagttgc cattatcaag
    24001 gggcatattg gattattgca gcgctggggc aaggacgata gtgctatttt agatgaaagc
    24061 ctcactgcag ctgcgcatga ggttgaccga atggctatta tgatcaatga catgcttgat
    24121 atgatccgag tacaggggtc ctttgaaggg catcaaaatg atacaactgt tttagagagc
    24181 tctattgaga ccgttgttgg taattttagg gtcctgcgtg aggattttga ttttacctgg
    24241 tactctgaaa atcaaagaac cctggccaag atttataaaa atcattttga gcaggctctg
    24301 atgattttga tagataatgc ggtcaagtat tctaggaagg aaaagaaaat cgtcatagaa
    24361 ttagcggtta atgctagcaa tgaagctgtg gttaaggtca aagacagagg tgaggggatc
    24421 tcagaagagg atattaagca tatttttgag cgcttctacc gcaccgatag gtccagaaat
    24481 cgaaccagca cccaagcagg tcttgggatt ggcttatcca ttttaaagca aattgttgat
    24541 ggctatcatt tacatatgga ggttgagagt gagctaaata aagggtcggt ctttattttg
    24601 cggattccct tagctgatca tcaaggctca tagctgtata cctgcctgag tatctagtag
    24661 atgctcaggc ttttgactat tctaatgtgt ggtgtgatga tggggtgttt atcagggaag
    24721 gagggctctt ggaggtaaac ctgagtgctt gtctattctt ttgttatccc taaaattatg
    24781 ataaaatagg gtattagatt aacgatagaa ttggggtgtt tgcgtgcgtt gtccgaaatg
    24841 taactataat aagtcaagtg ttgttgatag tagacaggca gaagatggca atacgattcg
    24901 tcgccgcaga gaatgcgaaa gctgtcacac gcgctttaca acctttgagc gcttagaaga
    24961 gcttccatta ctagtgatca aaaaggacgg gactagagag cagttttcaa gagataaaat
    25021 cttaaatggt gttgttcaaa gtgcccaaaa gcgtccggtg tcaagtactg acattgaaaa
    25081 tctcatttct cgcattgagc agaaggttcg tacagcctat gaaaatgagg tgtcaagtac
    25141 tgttattggc aatctggtga tggaggaatt agcagagctt gatgagatta cctatgttcg
    25201 ttttgctagt gtctataaaa gctttaagga tttagacgaa attgaagagc ttctacagca
    25261 gattactaat cgtgttagag gaaaaaagaa gagcagtgta gatgatgaag cctattgata
    25321 ccttttctta tattaagcat aatcaggttc aatacgattc aagcagcctg attcagctgt
    25381 actttcctat tattgggaat gacgcagtgg cagtttatca gtatttggtt cacttttttg
    25441 atgatggctc aggagcccac aaatttagtg atattttaaa ccatctgcag tttggaatga
    25501 agcgcctaga ggaagccttg gtgatgctga cagctattga tttgctggtc ttatatcagc
    25561 tgccagatgc ttatctgata aaactacatc agcccttggg cagggaagcc tttttaaata
    25621 acccaattta tcgtaggctt ttagagcaaa agattggaga tgtagcggtt ttggagttgc
    25681 aaatggtgat tccgaaccag gctagaaata tctcaaagac cttttcagat gtttttggaa
    25741 tagactctca ggagcttaag cagcctcagc catcaaagat aaattttgat ttagatagct
    25801 ttcagcagct aatgcggcgt gacggtctta ggtttgagga tcatcaaaag gacgttatca
    25861 gtctttacag tatttctgag caataccacc taacctggtt tgacacctat cagctggcta
    25921 aggcaacagc agtcggcggc agcattcgcc cagagcgcat gctagtcaag aagcagcaag
    25981 agggcgctca aaaaacaagt gaatctttct caccagctga gcaggttgtt cttagagagt
    26041 ctaagcagga cacgcctctt gtctttttgg agaagatcaa aaaagctagg cgagccaggg
    26101 tcacaaagga cgaaaaggac ctgttgctta ctctagctcg catgaatttc ttagacgagg
    26161 tcatcaatat tatggtatta tataccttca ataagaccaa gtcagctaat attcacaaga
    26221 cttatctgat gaaaatggca aatgattttg cttatcagca aattttgaca gcagaggctg
    26281 ctattatcaa gacacgcgcc tttggtgagc gtaagcagca ggcaaggtca cagcagtcca
    26341 atgtgcctaa gtggagcaat ccggattatc aagaaaaaac aagtcaggaa gaacaggcaa
    26401 agctagagca gtttaagcag gctgccttaa aaaggctgga gaacctagga aagagtggtg
    26461 actagatgga aaagatcggg aaaatggtag agcatttggg gcagactagt cgtgtagcta
    26521 gtgcagagct gattgaggct atacttgctg atcaggaggt ggctgagttt atcaaggctc
    26581 atcagctatc tcaggcagaa ataaagctga gtttatcaaa attcaatcag tttttagttg
    26641 agcgccagaa gtaccagaca ggtgatgaaa cctatattgc taagggctat caacccattt
    26701 tggtcatgaa tgagggctat gcagacgtgt cttacttaga gacaagagag ctggttgaag
    26761 cccaaaggca ggcagctatt gcagatcgca ttcatttggt tagcctgcca agatcttatc
    26821 gtagggtttc tttgtcagct gttgatgtta acaatgccag tcgtatgcag gtgttttcag
    26881 agcttttgga ttttgttgag caatacccat cagcagagca aaagggtctc tacctttacg
    26941 gcgatatggg ggtcgggaaa tcttatctga tggctgctat ggcacatgag ttgtctgaaa
    27001 aaaaaggcgt atcaacaact cttcttcatt ttcctagctt tacgattgat gttaaaaatg
    27061 ccatttcaaa tggctctgtc aaagaagaga ttgatgccat caagcatgtc cctgttttaa
    27121 ttttagatga tattggtgca gagcaggcga cctcatgggt gcgtgatgag gtgctgcagg
    27181 ttattttgca gcatcgtatg ctagaggatt tgccaacctt tttcacttcc aattacagct
    27241 ttgcagattt ggagagaaaa tgggcaaaga tcaaaggaaa tgatgagacc tggcaggcca
    27301 agcgtgttat ggagcgtgtg cgttatttag cacgtgaatg ccatttagaa ggggttaatc
    27361 gccgccagag ctagctaaac gctagctcaa gcgatggata atgagataag gaaaaggaga
    27421 atcatggttt tacctacagt tgccattgtt ggacgtccta atgttggaaa gtccacatta
    27481 tttaaccgaa ttgcaggaga gcgtatttct atagttgaag acgtcgaagg ggttactcgc
    27541 gatcgcattt acacgactgg tgagtggctt aaccgccaat tttcattgat tgacacaggt
    27601 ggtattgatg acgttgatgc tccctttatg gaacaaatca agcatcaggc tcatattgcg
    27661 atggacgagg cagatgttat tgtctttgtg gtttctggta aagagggcgt tactgatgca
    27721 gacgaatatg tctctaagct cttgtatcgt accaacaagc cagtgatttt ggttgtcaac
    27781 aaggtggaca atccagagat gcgaaacgat atttatgatt tttattctct tggcttagga
    27841 gatcccttcc cggtatcatc agttcatggt attggtacgg gtgatgtttt agatgctatc
    27901 attgataatc tgccggtaga agagatagta gaaaacgacg atgtgattcg ctttagccta
    27961 attggtcggc caaatgttgg aaaatcaagc ctcattaatg cgatcctagg agaagagcgt
    28021 gtcattgcca gtcctgttgc tggtacgact cgtgatgcga ttgatacaag ctttaccgat
    28081 gaatccggtc aagcctatac catgattgat accgcaggaa tgcgtaagtc cggcaaggtc
    28141 tatgaaaata ctgaaaaata ctcagtgatg cgtgccatgc gtgccattga ccgatcagat
    28201 attgtgttaa tggttattaa tgccgaggag ggcattcgtg actatgataa gcggattgca
    28261 ggctttgcgc atgaggcagg taagggcatg attatcgttg ttaacaagtg ggataccatt
    28321 gaaaaggata atcatacagt agctaggtgg gaggctgata ttcgcgatca atttcaattt
    28381 ctgacctatg cgccaattat ctttgtttct gctgttacaa agcagcgctt aaacaggctt
    28441 cctcagttga ttaagcgtat cagtgatagt caaagccagc ggatctcatc agctgtttta
    28501 aacgatgtga tcatggacgc tattgcgatc aacccaaccc cgacagataa gggacggcgt
    28561 ctaaagattt tctatgctac acaggtttct gtgaagccgc caacctttgt tgtttttgtg
    28621 aatgaagaag agcttatgca cttctcctat ctgcgctttc tagaaaacca gattcgtgcc
    28681 gctttcacct ttgaagggac accaatcaag ctgattgcgc gcaatcgcaa ataggctctc
    28741 ttattgctct ttttagcgtt gaaagcagcg agtgctgttg atgtgcggtg tctagacctt
    28801 gtgtgtcagg acttttgact gataagcctt accagaaatg agaggctgct atccaaatag
    28861 agcttaccag caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag
    28921 gctagtgatt ttttagtgct ttaaagccta tcaaaatagc tatgtgtagt cacttaaatg
    28981 tgttttaatg gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat
    29041 caaaggataa gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc
    29101 aatcaaggca tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac
    29161 cttcttcgag cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt
    29221 aggtgtcagt gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa
    29281 tattttctga aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg
    29341 gaaagtaagg aggaaactaa aaagttgacc tcctttggca gtcttttttt ggacagtttg
    29401 caaatgaatg aggacgacac gaccaaatat aggcttttag cctttggtgc caaaagcccc
    29461 ttttcgtctg attactggtg gagccttaag ataaatcgct tgcccggcga gaaggcttat
    29521 gttatccgag atattaaggc ttttatccat ttggtcaaaa tcgaaggcta ttaccagatt
    29581 ggaaagaatt attttgagtc tctttccata ttgcagtttg atcaggctag ccaggatttg
    29641 attcgttttc tttggcgctt atcaacgcat tcagataagc tagattacga atggctattt
    29701 cctaaccacg ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg
    29761 ctgacggggc tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat
    29821 gttcgacctc tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc
    29881 tctattgagc tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg
    29941 ctatacatga acacctttta tcacctgagc ctgaagcagc aaaaaatggt tcaagctatt
    30001 cgtagcctcc ctattgaggc tgatttggct aagcatattc attttgatct tgatgatcag
    30061 gctaagctgg cagctagctt gttagaattt cgagagcttg gtcaggtgaa ggctcctaaa
    30121 agctttgata ttagagattt ccaagtgact tttgtctttg atattactga aaaaggcgag
    30181 ttgacctctc agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta
    30241 gatcagctcc cctttgctag ccattataaa aaagaaaacc gtatttatcg tgccttgaag
    30301 cgctttggtc tttccccgca gttttttgct aaaaaagctt tgactgatcc caaggactgg
    30361 tatcgctttt ttacagaggc tgttccttat tttgaaagtc taggtagggt tcagctctcc
    30421 tctaagcttc aagatcagcg cctgctggaa agccctcagc ttacggtcaa acgtgagggt
    30481 ggtcttttag atatttcctt tgatttttca acggtttgtc aggctgatat tgaaaaggcc
    30541 ttagccactt tatttagtga cagctcttat tttgtcaatc agtcaggcaa gctggtcgtt
    30601 tttgatgaag agacacaaaa aatcagccgt agcttacagg agctaagagc taagcagctg
    30661 gcaaatggtc accttcagct agaaggaata gctgccaccc agctgtctca tctgttttcg
    30721 gatctgtctt ctgtccattt ttctgaggag ctagagaccc taatcaagga tctgcagcac
    30781 ccggatcgct ttgagctggg agagctagtc gttaaggcca aggtgagaga ttatcagctg
    30841 cagggcatca aatggctatc tgtgcttgat aagtatggct ttggtggtat tttggcagat
    30901 gatatgggct tgggcaagac gctgcaaatc attgcctttt tatcaagcag gctaaccaag
    30961 acctccaagg tgcttatctt ggcaccctct agcctgattt acaattggtt agatgagttt
    31021 agtaaatttg cccctcagat agatgttgct gtatcctatg gactaaagcc agcacgagat
    31081 gctcttattc gagaaggaca tcaggtgacg attaccagct attcctcctt tagacaggat
    31141 ttggagacct atcaggcaag tgattatgat tatttaatct tagatgaggc acagatgatt
    31201 aaaaatgctc agaccaaaat cgctcaaagc ctgcgtgcct ttgacgtaaa gaactgcttt
    31261 gccttatccg gtacgccgat tgaaaataag ctacttgaaa tctggtccat ttttcaaatt
    31321 gttctgccgg gcctgctacc gtctaaaaaa gcctttttga aaatggaagc taaagatgtt
    31381 tctcgctata ttaagccctt tgtcatgcga cgtaaaaaag aggaggtctt accagagcta
    31441 ccagaattaa tcgagatgag ctattacaat gaaatgtctg atggtcaaaa agcgatttat
    31501 ctggcccagc taaggcaaat gcaggagcgg ctgtctgctg caactgatga tgatattcat
    31561 cgcagcaaac tggaaatcct atctggtatc acacgtctaa ggcaaatttg tgatactcca
    31621 agcctgttta tggattatca aggaggaagc ggtaagctag acaatctaag aaccctgctg
    31681 ttgcaaatca aagaaaacgg tcataggact ttgctgtttt cacaatttaa gggcatgctg
    31741 gctcttgtca agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca
    31801 acaccggcca atgaccgtca agaaatgaca cgagccttca ataatggctc aaaggacgct
    31861 tttttgattt ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgacactgtt
    31921 attttgattg acctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat
    31981 cgtattggtc aggaggacaa tgtagaggtt taccggttga ttacacgcgg aacaattgaa
    32041 gaaaaaatgc tggagcttca ggaaaataag cgtcatctga tcaccaccgt tttagatggc
    32101 aatcaaggcc tggcaagcat gtctgtcgag gagatcaaag aaatccttgg ccttcagcct
    32161 tagcctacat agcttttagc acatgctctt aagcttatca gctaaagcca gtgtccgtcc
    32221 tctataaaca aataaggcag gagagcagag gtgatgagct agtcacatca tttttgcttt
    32281 gctgcctttc tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa
    32341 tgctatagga aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg
    32401 gtgagcctat tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatta
    32461 caaatattgc tggcagctat caagacaaac attacgacga catcataaga gaccatcaat
    32521 ttgctgagaa agctcctgtc gtctctaaag aatcccttca tcattctcca gctgtcgatg
    32581 aagatcatag ctacgctcaa aaggccagaa ggcaagcaaa gcaagctgtc aaagaaaaaa
    32641 gacaggctta tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc
    32701 aaagtggggc cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat
    32761 taaaccaaga gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata
    32821 ccagccaagc agctatcaaa aaaaataatt atgatttttt gaagcgcagc caaatttaca
    32881 atcatcaaga agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc
    32941 gctttgagga tattaagtaa gctttataaa gccttatacc tgtcaacatt aaaaggagtt
    33001 aacatgtcaa aaacctatca ttttatcgga attaaaggag ctggaatgag tgctctagcc
    33061 ctgctgctcc accaaatggg gcataaggtt cagggcagcg atgtggagaa gtattatttc
    33121 acacaaagag gcctagagca agcaggtatt accattttgc cctttagcga agataatatt
    33181 tctccggata tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt
    33241 gcttatgcaa tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt
    33301 atgaagcagt ttaccagcct aggtgtggca ggggctcatg gaaaaacctc taccacaggc
    33361 ttgctgtcac atgtgctcaa gcatatggcg gctacttctt atttgattgg tgatggtact
    33421 gggcatgggg ctgctgatgc tcgttatttt gtctttgaat cagatgaata tgagcgtcac
    33481 tttatgcctt atcacccgga gtattccatt attactaata ttgattttga tcaccctgat
    33541 tattttacgg gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa
    33601 aaagctcttt ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcgccg
    33661 atttactatt atggctttga ggatactgat gattttgtag cctttgatat cacacgtacc
    33721 acaaatggct cagactttaa ggtaaggcat catcacaagc ttatcggtca atttcatttg
    33781 ccggcctatg ggcgtcacaa tattttaaat gctactgcgg tgattgccaa tttatttatt
    33841 gccggctttg atatgaagct tgttgcagag catttgaaga gcttttcggg ggtgaagcgt
    33901 cgttttactg aaaaggtgat caatgacact attattattg atgattttgc tcatcaccca
    33961 acagagatca ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatt
    34021 gctatttttc agccacatac ctttacaaga accattgctt tgctagacga ctttgcccat
    34081 gccttaaatg aggctgacag tgtttatcta gcgcctatct atggctcagc gcgtgaaatt
    34141 gataagggtg atgtcaaggt ggaggatcta gcggctaagg ttgagcgccc agctaaggtc
    34201 atctcagttg acaatgtatc gccgctgctg gatcatgaca atgcagtcta tgtttttatg
    34261 ggagcaggcg atattcagtt gtacgaacgc tcatttgaag agctgctggc taacttgacc
    34321 aaaaataatc aatgattgaa ccacctgcct taggcaggtt ttctcatcgt aaaggaggac
    34381 ctatgctaat tagacatgtg aatcagactg actgggagat tattgctgac attgaacagg
    34441 ccaatttttc tccccaagag gctgtagcaa aagaagtgtt caaggagcga acaaggctta
    34501 tttcggatac ctttcttgtc gcagttattg ctaatcagct tgtcggctat atcgaaggtc
    34561 cggttgttgc tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag
    34621 caaggggtgg ctatatagcc attaccagtc tttctgttgc tcctggttac caaaagcagg
    34681 ggattggcac agctctccta gctgcaatga aggatttagc agttgcacag gatcggctgg
    34741 gcattatact tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag
    34801 atcaaggcct gtcagcttca cagcatggtg gctctgtttg gtatcaaatg ctatggcagc
    34861 cagaggaagg atattaaggc ttagcatgta ttaagaatta gtaacaaaag ggggatttta
    34921 ttgcatttat agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt
    34981 tgactgattt taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagagaaga
    35041 ttctagccga attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta
    35101 aaaaggatct agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata
    35161 aaagacaaga agcactaagc aataacccca aacaagcgtc cagtgatgta gcagctgtat
    35221 cacaacagac gacctcaaca gctcacacct ctgcgactaa gctagaagag acagcagtag
    35281 ctgctgagga tcaagcagtg tcgtcaccag aggagcctgc attgagtgag agcctgctca
    35341 aggaggaggc aagtgtcgaa ggtcagacta agaagggtgg tccagtgaga agaaaagtaa
    35401 gcaagcgtca gcagacagat cgaatggcca aaaaaatttc gacaatactg atatcgtcta
    35461 ttgttgctat tattgtggtg attggcctag cagggacagc ctatgtctat agtgccctta
    35521 accctgttga taaaaatagc gatgactttg ttcaggttga aatcccagcc ggctcaggca
    35581 ataagcttat tgggcagatc cttgaaaaag aggggctgat caaaaatagt accgtcttta
    35641 gcttttacac taagtttaaa aatttcacta attttcaaag tggctactac aacctacaaa
    35701 agagcatgag cctagaagac attgcccagg ccttacaaga gggtggcaca gcagagccta
    35761 caaagccagt actaggaaaa attttaattc cagagggcta taccattaag caaattgcta
    35821 aggccataga aactaatagt agggcaaaga atcgtagcaa ggctaaaaca ccatttcgct
    35881 caaaggattt cttgaatttg gtgacaagtg atgcctttat ccaagagatg gctaaaaaat
    35941 atccgaaatt gctaggagat cttccaagca aggaagtagc tacttatcag ctagaaggct
    36001 accttttccc tgcgacctat aattattata aggaaacaac attaaaagac cttgcagagg
    36061 aaatgattgc agcggcaaat gcaaacctag cgccttatta tgaggcgatt gcagctagcg
    36121 gcaagacagt taatgaggtg ctgactttgg cctccttagt tgaaaaggaa ggctctactg
    36181 atgacgatcg gcgtcaaatt gccagcgtat tttacaatcg cttaaataat ggcatggcct
    36241 tacagtctaa cattgctata ttgtatgcaa tgggtaaatt gggagaaaag acaaccttag
    36301 cagaggacgc tgctattgac acaaccatta attctcctta taatgtttat accaatactg
    36361 gcttaatgcc tggtccagtt gatagtccag ggcttgcagc tattgaggcg actatcaatc
    36421 cagcggcaac agattacgtt tattttgtag ccgatgtgcg tactggtgag gtttattatg
    36481 caaaaacatt tgaagagcac tctgcaaatg ttgaaaaata tgttaacagt caaattcagt
    36541 aaggacaaac atggtgcttt agcatcatgt ttgtgtttct gattcgtcaa aagaaaaagg
    36601 aaaagagaaa gataatggca gaaaagactt atccaatgac agcagcagaa aaagaacagc
    36661 ttgaaaagga attagaagag ctaaaattag ttcgtcgtcc agaggttgtt gagcgcataa
    36721 aaatcgctcg ttcgtatgga gacctttctg aaaactctga atacgatgct gctaaagatg
    36781 agcaggcttt tgttgaggga caaatctcaa ccttggagac aaagattcgc tatgctgaga
    36841 ttattgatag cgatgctgtt gccaaggacg aggtggcgat tggtaagaca gttgttgtcc
    36901 aggaggttgg cacacaaaca acagacactt atcatattgt cggtgcggca ggagcagata
    36961 ttttttctgg aaagatttca aacgagagtc caattgcaca ggccttgatt ggtaagaaaa
    37021 caggagataa ggttaagatt gagtctccag cagctaccta tgaggttact atcatcagtg
    37081 ttgacaaaac acaataagac ttatctgact atcagtgcag tgtcctgata gtctttttag
    37141 tggcttgctt ttttaatatc agttgttgtg gtctattaaa aagcggctga aaccaaaaga
    37201 tctgtacttt agaaagtctt aactaagata ctttatgacc tagtctcatt cattaaaaaa
    37261 gcgaacaggt ctagctttca gagattctga aaacgagacc tgttcgtttg ttttatcttg
    37321 agtcagactt ttgtcacaga ctcttttagc tatcttagct gcgctttttt tgtttaccgg
    37381 cgtttcggtt tgacttagtc ctcttgcttg tactaagggc ttgcttttca gctgtaacgt
    37441 ccttgcgtag ctggtgagat ttataggcct taggagggtt ctttgcgaac tcctctgcaa
    37501 tttgcttgcg gagccttggc tttagaaggt aggttgtgat caattgctga atgatgctaa
    37561 agaaaccacc aactagccag tacaagccta atccggcagg caggtaaaac gacatgacaa
    37621 tcatcataat tggcatggtg tacagcatgg ctttcatctg ctcgcgttgc tcctcaggga
    37681 ctgccatcat tgacagccag gattgaacga agtataaagc cgcaattaca gctgtaagca
    37741 agacgctgcg atgccccagg tcaatgccca taaaggtact tgttgagact cccttggtaa
    37801 attggaccgc aacatacatg gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc
    37861 ctatgccacc tagcgggttg actccatttt cacgctgggc cgccattaat tctgtttggg
    37921 ctgccatttt ttcttcagtg cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa
    37981 aaggctttag gtaggccatt ttttctgatt ggtagcttgc cttccatgat tggtagagcc
    38041 caagtggcaa aataatggtt ctaacaataa tagtcacaac aatgatagca agaccatagc
    38101 ctagggcggt gctgttagca aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat
    38161 cccaaatgat gccctccggg tgccccttgg cgtctctgcc gacacaccct gtcaatgtca
    38221 gtaggaccga taaggcaagt cctgagaaaa gtatgcgatt tgttttgagt ttcaatgtgt
    38281 ttatccttta atttttaata tacctaacca ttttactgtt tttttgagaa attaacaata
    38341 gttctacagt aggattttta attgctgatc ctaaaatcat ggaaatcctc aaagtgagat
    38401 gggctaacat caacataggt tacctttgcc catttagaag gcccttttct gattttctgg
    38461 ataaagcgcg ttatctttgt gggatcatta gcctgtgcta aaatctcaac agtcccatcg
    38521 ctgttgttcc acacgcggcc gtaaatatca ccaatttcca aagctagtgc gtaggttgaa
    38581 tagcgaaagc caacaccctg aaccctgcct gaaatgatta gtctgacctt tttcataagt
    38641 cacctctttt ctttttatta tagcatagat agcttataaa tactaaaagt tgccatagag
    38701 cagacagcta aagaataggc aaaggctata agtgggttat ctgctgaggt aaacaatagg
    38761 tcttagtgca gcaagactgt gcttatgatt agctctcctt cttgtctttt aagggggaag
    38821 ctgatgagct tacgacacct gatgagggga gaaagctcct tttaagctga tagccttctg
    38881 atggttttta tgccaaagag tgaactattt tgtggtataa taagaccatg attatcacat
    38941 caaaagcaaa tcgtttgatt aagcaggcta agaaattact gcaaaaaaag caccgtaagc
    39001 actcttattt gattgagggc tggcacctat ttgaggaggc tcagaggtct gggcaggaat
    39061 tgatacatat ttttgttctg gaggaaatgg cagagcgctt atcaggcttt gatcaggttg
    39121 tcatcgtcag tccagagatt ctaaaggagc tgacgagctc tcccaatcca cagggcatta
    39181 ttgctgaggt taagttttgt caacaggcct taccgactag ctatgctggg aaatatttga
    39241 ttttagagga tatacaggat ccaggcaatc taggaacaat catcagaaca gcggacgctg
    39301 caaactttga tggggtgttt ttgtctgaga agtctgcaga tatctataat caaaaaactc
    39361 tacgctccat gcagggcagt cattttcacc tgccgatttg gcgaacggat atttatcagg
    39421 ttagtcaggc gatgcagcag caaaaaatac cagtgctggc gacaaccttg tctcaggatt
    39481 cgattgatta caaggacctc tcagctagga gcagccttgc ccttgtttta ggaaatgaag
    39541 gtcagggcat tagtcctgag atggcagctt tggctgatca gctgattcat attagcatgc
    39601 ctggacaggc tgaaagctta aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa
    39661 tttaagctag tatggtataa taatgatgtg aggtgattag tgtatgcatt atacagaaga
    39721 tatagaatac atggagcatg ttggtcattt gattgctcac cctcgctttc aaaggcttgg
    39781 agatattgtt cagcatcacc attctactcg cttagagcac tctgtcaatg tttcttattc
    39841 tagctatagg ctggcaaaga ggcttggctt agacgccaag agtaccgcac gaggtggctt
    39901 gctacacgat ttcttttatt atgattggcg agtaaccaag tttaacaagg gacacgcttg
    39961 ggtgcaccct agaattgctg ttcgaaatgc taaaaaatta acagcactca acaaaaaaga
    40021 agaggatatt atcctaaagc atatgtgggg agctactatt gcttttcctc gctataagga
    40081 aagctatatt gttacctttg ttgataaata ttgggcggtc aaggaggcca tgacgccgct
    40141 gcgtcaaaaa tggacgaacc gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca
    40201 ttaagtaaaa aaaaggagtt atgatgaacg ataatgttat ttacacacag tctgacgcag
    40261 gcttgagcca tttttttgcc aaggtctata gcctggttgg tatgggagtt gggctttctg
    40321 cctttgtttc ttatttgatg ctgtttccgt ttaggcaaaa tttagtgtcg attattcttg
    40381 accatcctat ggtctattat ggggcggcta ttgttgagct tgtactggtt tttgttgcta
    40441 gtggtgctgc acgtcgcaat acaccagcag ctttaccctt atttcttgtc tattcagcct
    40501 taaacggctt taccttgagt ttcattattg cggcttatgc gcaaacaacg gtgctacagg
    40561 cctttatctc atcggcagct gttttctttg ctatgtcact gcttggtgtt aaggttaagc
    40621 gtgatctgtc aggtattcga aaggccatgt ttgcagcctt gattggaatt attgtagcta
    40681 gtctggtaaa tctctttatc ggtagtgacc tgatgagcta tgtgatcagc cttatttcag
    40741 tgttgatctt ttctggcttg atcgcttcag acaaccagat gattaagcag gtttaccaag
    40801 cctctaatgg tcaggctggt gatggctggg ctgtcgctat ggctcttagc ctatacctag
    40861 actttatcaa cctctttatc agtctacttc gtctcttggg aagaaatgac taatagctat
    40921 tttaagcgca gttgctgatt gtcacttaat cgctattacg agaaattagc aaggctgcaa
    40981 gtgttacctt ttgttagaaa agagtggctg ctgctagtaa gaaagtagct gctaggagag
    41041 cctgaggagt gtgaccgtca aggaaggcca gttactatcg ctaccatctt gggaaggtac
    41101 caaaaaagaa aagccaagaa gcgggcctaa gggctcgttt ttgtttgctt gatttgtggt
    41161 aaagtgcttc aaaccaagcc tatatctagt ctgatagctc ttatcagctg acaacatcat
    41221 atttacaatg cctgttggtg tagatttgta aagcatgctc ttttttggta taatgagaag
    41281 aacaaaaaat cgaggagaat atctatcaat atgtctacag ctatctggat attattaatc
    41341 attgttgctc ttacagccgg tctttttggt gggattttta ttgcccgtaa gcaaattgaa
    41401 aaggaaattg gggagcaccc acgattaacg cctgaggcca ttcgtgagat gatgagtcaa
    41461 atgggtcaaa aaccaagtga agcgaaaatt caacaaactt accgcaacat tgtcaagcaa
    41521 tcaaaagccg caatgactaa gggtaaaaaa taggctacgg attagaaatc gtggtttcta
    41581 agcaatagct aagagtgaac agtctttgat gttaaaagct tgcttagagc ttgcattgtc
    41641 agttagaggt gtcaactgtt cagggtttaa caatagactc agttggctct taccagctga
    41701 gttttttatg cttcaatgag gaaataatcg ttatggataa tagaccaatt ggttttttag
    41761 attctggtgt aggaggctta accgttgtta gtgagctgat gcgtcagctt ccccatgaaa
    41821 aaatcattta tattggtgat tcagcaagag ctccttacgg ccctagacct gctgaacaaa
    41881 tcagagaata tacctgggag ctggttcgtt ttttgttgac gaaacatgtc aagatgattg
    41941 tctttgcttg taacactgca acagctgttg cttgggagga ggtcaaggag gctctggata
    42001 ttcctgtttt gggggttatc ctgccgggcg ctagcgcagc tatcaaggct actagtggag
    42061 gaaaggttgg tgttattggc acatcaatga ctatttcttc aggcatttac caggaaaaga
    42121 tccagctgct ggcccccact gttcaggtaa ctagcttggc ctgtcccaga tttgtcccaa
    42181 ttgtggagtc caatgagata agctcaagtg tggccaagaa aattgtctac gaaacgctgg
    42241 ctcccttagt tggaaagata gatacccttg ttttgggctg cacccattat cctcttctta
    42301 ggacgattat ccaaaatgtg ctgggaccac aggttaaatt gattgatagt ggggcagagt
    42361 gtgtgcgtga tatttctgtt cttttaaatt attttgagat taatggtagt cgagatgatg
    42421 aacataggcg tcatcatttt tacactacag ccggctcaga cagctttcaa gcaattgcct
    42481 cagcctggct aaatcaaacg atagatgtgg agcatgtgac cttatgagtg ataacattta
    42541 tgaatacaag gataaagaca attggtttat tggaaagatg acaggccata atttaatggc
    42601 tggctggggg gttaaccatg agcttattgc caaaatagac gatatgttag gtgcgattgc
    42661 tggtgatgtg gattgggaaa gtccggtcgg ttatgatgtg actgttattc gttacgcctc
    42721 cccttttgcc ttgattagct ttgttgttgg catgatcaat cagaaagcca atcgagccct
    42781 taaggttgtt cggcactcag gtgcggtttt agtgaccgaa aacgagcgat tgcttgctgt
    42841 gcatatgcca gatgatggtg tccctgtggc tgacttcttt ggtcaacaga caggtggctt
    42901 tggggatacg attttgattg cgactcgaaa tgaaggcaag accaaggaat ttcgccggct
    42961 ttttggtgat atgggatatc gcgttgaaaa tctcaatgat tacccagagc ttccagatgt
    43021 ggcagaaacc ggggtcacct ttgaagaaaa tgcccgccta aaagcagaaa ccatttcaag
    43081 gcttactgga aagatggttc tggcagatga ttcaggcctc aaggtggata ttttaggtgg
    43141 cttacctggg gtctggtcag ctcgtttttc gggccctgat gctactgatg agactaataa
    43201 tgctaagcta ttgcatgaac tggcaatggt atttgagcaa aaggatcgct ctgctcaatt
    43261 tcatacgacc ttggtggttg ctgcacctga taaagacagc ttggttgtcg aggctgattg
    43321 gcatggctat attgcgacca agccaaaagg tgagcatggc tttggctatg atcccttgtt
    43381 tatcgttggg gagactggac gtcatgcagc agagctagct gccgatgaaa aaaacaagct
    43441 gtctcatagg ggacaggcgg tcaagaggtt aatggaggta tttccagcat ggcaagcaaa
    43501 acaatcattg tgatgagcga ttcgcatggc gatcgtgagg ttgtggcagc tattaaaggc
    43561 cgttaccttg gaaaggttga tgccattttc cataatggcg attctgagct agaaagctca
    43621 gatcctattt gggaggggat tcatgttgtg gcaggcaact gtgaccatga tagcggctat
    43681 aaggatagcc tagtcacctc ctttgatggc ttgactattg ctcaaacaca tgggcatttg
    43741 tatcatatta actttacttg ggataggcta gattattttg ctcaggagac tggagcggat
    43801 atttgtttgt atgggcactt gcacagacct gctgcttggc aattgggcaa gactgtcttt
    43861 atcaatcctg gctcggtcgc tcagccgcgt ggtgaggtga atgaaaagct gtacgcgcgt
    43921 gttgaatgga cagcagcttg cattagggtg gattacttta cctgtcagca taagccttac
    43981 ccatcacttt ctaaggaatt taaacgatga tagcaaaaga atttgaagcc tttttaatca
    44041 gtcatttgga tagctacctg attccggcag aggagctagc tatttttatc aacacgcata
    44101 atgctgatca tgtcatgctc ttattggtta gcaatggttt ttcacgagtt cctgtcatta
    44161 ccaaggaaaa gcaatatgtc ggaacgatca gcatttctga tataatgacc tatcaagcca
    44221 aaaggcagct aacagactgg gagatgacgc aaactaatat tggcgacatg gtcaatacaa
    44281 agattgagac catcaatatt acctctagct tgactgaaat catgcataaa ttggttgatt
    44341 ttcccttttt accagttgtt aatgatgaca atcgatttat cggtattatt acgcgtaagt
    44401 ccattttgaa ggcggttaat agccttttgc atgacttcac tgatgaatac acaatcacaa
    44461 aaaaatgata gcatttattg aaccctttct agcaagcaaa tctcttgcta ataacagcca
    44521 gcaatcctat cgctatgatt taaggcagtt ttgccagcag gtcggacagc gtattaatcc
    44581 tgaaacccta gccctctatc agcaaagctt gtctggcctt acggtagcag ctaaaaagcg
    44641 caagctttca acggtcaatc agtttttgta ctatttgtac cagcagagag ttttagcaga
    44701 ttattttaaa atggacgata ggatagaagc ctctttttct ttgaagcccc agctgacaag
    44761 gcttgacacc agcgcttttt atgctgaaac agccttccta aaaggtcagc tcattgcgct
    44821 gctgattctg gagctgggct tgacgccaag tgagatagca gggcttcgtc ttgctgattt
    44881 tgacctgggt cttcaggtgt taaggctgca atctcaccga ggcattcgtg tgatgacctt
    44941 atcaagaacc ttgctgccat ttttggaaag ggcagcagaa gctcagcagc tctacctctt
    45001 tgatcatgac gccaagccct tttcaaggca atggtttttt aaccagctca gagatttttt
    45061 agagagcatt ggctgtgcgg agctttcagc ccagagcttg agagagcaat tcattttaaa
    45121 tgaaaaagca gccggtaaat ccatcattga ggtggctcag ctgctggggc taaaaagccc
    45181 gatcacctta gaaaaatatt ataagatgta atggatataa aagtaaaaga ttttgaaggt
    45241 cctcttgatt tactcttgca cctagtgtca aagtatgagg ttgatgttta ccaggtgcct
    45301 attgtggatg tcattgaaca atacttggcc tatattgaga ccttgcaggc gatgcgcttg
    45361 gagcttgctg gagagtacat gctgatggct agtcaactga tgctcatcaa aagcagacga
    45421 ctgctgccaa agctagtaga caaggagcct gatgaggagg atcttgagca agagcttttg
    45481 ggtaagattg aagaatatag tcgtttcaag gctctgagtc aggagttggc cagccagcat
    45541 gacaagaggg ctctgctttt ttccaagcca aagcaggagc tgatctttga gcaggccgtc
    45601 ctacaaaagg ataaaacggt catggatttg tttttagctt tttctcagct aatggctgca
    45661 aagcaagagg cctttaaaca taaccataca gtcattgagc gagatgatta tcgtattgag
    45721 gatatgatgg agcttattga agctaggctt gagctagagc aggagcttgc cttaacggat
    45781 ttattgaagc attgtgacca tcttaatgag gccattacct tatttttagc aagcctagaa
    45841 ttaatcaaac ggcagcttgt tggtgttgag cagacatcac agtttggcca tattgttttg
    45901 cgaaaggagg tccaatgacc tatttatctc agctggaggc cttgctgttt gtcgcaggag
    45961 aagaaggcct aagcctacgt cagttggcca gcctattaga attaacaccg acagccttac
    46021 agcagcagct cgacaagctt tctcagaaat atgaagagga taaggaatct ggcctgtgct
    46081 tgattgaatc ctctaggacc tataagctag tcaccaagga gtgtctggct cccttgctta
    46141 gagactatgc taaggctcca atcaaccaaa ccttgtcacg agccagcctg gaggttttgt
    46201 caatcgttgc gtataagcag ccgataactc ggattgaaat tgacgagatt cgtggtgtca
    46261 attcaagtgg tgcccttagt aaattagtgg cctttggcct gattcaagag gctggcaaaa
    46321 aagaagtgat tggtcgacca aatctttatg cgacaacaga ttactttctt gattatatgg
    46381 gcattaatca tttagaagag ctggtcgaca tttcttctat tgctgttgaa gagcaagaga
    46441 caaccttgtt ttaagagcaa atagaagctt gtctcatttg cagataggcc ttatgctccc
    46501 tagtaaaaga gcctttagca taacagtctt agcaaggtat ggtgcctgaa aatcctattg
    46561 ttgttatagg cagtggtctt tttagatatg ctattaaata agagtagacc tgtttaagct
    46621 agtgagcttt tacccatacg agagtggctg gtctgttgga gctatcgtca gatttcctaa
    46681 taagaaagag agaaggataa tgagaattaa taaatacatc gcccatgcag gcgttgctag
    46741 ccgtcgtaag gctgaagagc tgatcaaacg aggactggtg actctaaatg gtcaggtggt
    46801 aaccgattta gcaactactg ttaaatcagg cgaccttgtt gagatagagg ggagtcccat
    46861 ttacaatgaa gagaaggttt attatctcct caacaagcct cgtggtgtca tctcaagcgt
    46921 ttcagatgat aaggggcgtc agacagtgat tgatttgctg ccgcaggtta aggagcgcat
    46981 ttaccctgtt ggtcgcttgg actgggatac ctctggctta ttaattttga ccaatgatgg
    47041 tgattttaca gataaaatga ttcacccccg taatgaaatc gacaaggtct atctggcccg
    47101 tgtcaaggga gtggtaacta aagaaagtct gcgtccctta acacgtggtg tcgtcattga
    47161 tggtaaaaaa acaaagccgg ctcgttaccg cattattcgt gttgagcctg ataaaaatcg
    47221 ctctattgtt gaactaacca ttcatgaggg ccgtcatcat caggtcaaga aaatgtttga
    47281 agtggttgga cacttggttg ataagctatc aaggacacag tttggcagcc ttgatgtcag
    47341 aggcctaaag cccggagaag ccagaaggct gagcaaaaaa gaaatcagcc agctacatca
    47401 tttagcgagc acacgaaaat gatcaaagcc ctactcattg ctcctgtcag agcctatcag
    47461 aaatatattt ctcccttatt tcctccttcc tgtcgttatc agccgacctg ctcggcctat
    47521 atgatcacag ctattgaaaa gcatggagct aagggtgttt tgatgggact tgccagacta
    47581 ttaaggtgcc acccttttgc tgctggcggg gaggatccgg ttccagatac cttttcccta
    47641 aaaagacatt tcataaagca tgaaaaaata caggattttg accacaaaac tgattgacaa
    47701 tagcagttaa agtgctataa tagcagttaa gtattcgttg gtttaaatca aacctgttat
    47761 gatttaagtt agcgagtcac cgtcaaccac attgtttgct gagcatgact ccgggcagtg
    47821 tggttttttt gatgaaaaga gtaagcgaga caagcatgaa acaagaaatc attaatagac
    47881 aatataggga aaaagatagt caaaaccatg tggtgctctt tcagccacaa attccacaaa
    47941 acacaggaaa tattgctagg acctgtgctg ccaccaacac gcctttacat atcatcaggc
    48001 ctatgggctt tccgattgat gaccgtaaga tgaaaagagc ggggctagat tattgggata
    48061 agctagatat tagattttat gatcatctag atgaattttt agcacaatgt gatgggagtt
    48121 tgcatgtgat tagcaaattt gctgataggg tatactcaga tgaagcctac aatgatcgtc
    48181 agtctcatta ttttttgttt gggcgtgagg atactggtct gcctgagccc tttatgcgtc
    48241 aatatgctga tagggcactc aggattccta tgaatgatga gcatgtcaga agtctcaatg
    48301 tctctaatgc tgtttgcatg atcgtctatg aggcacttag acagcaagcc tttaaaggct
    48361 tagagcttag ccatacctat gagcatgaca aactaaaatc ataataagca tatcgcaaaa
    48421 catcagttag attgaagaag tatccgtagg ggagcttctt cagtcttttt tttattgtct
    48481 tctttttgct gttgaccaag cagttgacac gaaaattcca atagatagtt taaagccaat
    48541 aaaaccatta ttaggcttgc attacagaca ggtatcaaac aaagatatag aaaaatatac
    48601 cagaaaaaat ctcataaaag tgtcaaaatg gtaaaaattg ccaacaatat gtcaatatta
    48661 taccgttatt atagtataat atttataatc atattataat
//
LOCUS       DARYSY010000011        46323 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYSY010000011 DARYSY010000000
VERSION     DARYSY010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46323
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(104..256)
                     /locus_tag="TVR04_000529"
     CDS             complement(104..256)
                     /locus_tag="TVR04_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269243.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPIVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(253..1632)
                     /locus_tag="TVR04_000530"
     CDS             complement(253..1632)
                     /locus_tag="TVR04_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1269244.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTRFATAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFIATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGAQALETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYAALTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVISA
                     NKEKASDLS"
     gene            complement(1707..2141)
                     /locus_tag="TVR04_000531"
     CDS             complement(1707..2141)
                     /locus_tag="TVR04_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1269245.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKNKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEERTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            complement(2141..2476)
                     /locus_tag="TVR04_000532"
     CDS             complement(2141..2476)
                     /locus_tag="TVR04_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1269246.1"
                     /translation="MTQPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTSLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEQ"
     gene            complement(2479..2790)
                     /locus_tag="TVR04_000533"
     CDS             complement(2479..2790)
                     /locus_tag="TVR04_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1269247.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALAMME
                     E"
     gene            complement(2804..4798)
                     /locus_tag="TVR04_000534"
     CDS             complement(2804..4798)
                     /locus_tag="TVR04_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1269248.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLTSKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEKLCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HVMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            complement(4904..5998)
                     /locus_tag="TVR04_000535"
     CDS             complement(4904..5998)
                     /locus_tag="TVR04_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1269249.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKLYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLVGLRLDEALP
                     LEDIVRLMKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRYLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVADIKEDYLSLLDELKPWQEFSLVIETD"
     gene            complement(6008..7408)
                     /locus_tag="TVR04_000536"
     CDS             complement(6008..7408)
                     /locus_tag="TVR04_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1269250.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQEKGGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVALLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPNKIRQDGDPITLASYFELYDMPGK
                     KVNPHRGWEIYEQGLYDIAITLKEHYGNIDWLVTENGMGVEGEEAFLADGQVQDDYRI
                     AFIKDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            7984..8688
                     /locus_tag="TVR04_000537"
     CDS             7984..8688
                     /locus_tag="TVR04_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1269251.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQGLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTGLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            complement(8741..8899)
                     /locus_tag="TVR04_000538"
     CDS             complement(8741..8899)
                     /locus_tag="TVR04_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269252.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(9019..10332)
                     /gene="obgE"
                     /locus_tag="TVR04_000539"
     CDS             complement(9019..10332)
                     /gene="obgE"
                     /locus_tag="TVR04_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1269253.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFDELPMIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADFAEDEAYYGFASEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            complement(10386..10514)
                     /locus_tag="TVR04_000540"
     CDS             complement(10386..10514)
                     /locus_tag="TVR04_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1269254.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            10736..11977
                     /locus_tag="TVR04_000541"
     CDS             10736..11977
                     /locus_tag="TVR04_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1269255.1"
                     /translation="MVLPHFDEHLEKYANLLIKKGVNIQKGHTLLITIAVEHHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRTATQANKVSWNLAAAASPEWAAMVFP
                     KLTTEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKAKLLNDYQFDSLHYRAP
                     GTDLKLGMPEQHIWEAAGSTNAQGEVFIANMPTEEVFTAPDYRRADGYVSSTKPLSYA
                     GVVIEDMTFTFKDGQIVDVTAKKGEDTIKRLISENEGARSLGEVALVPHKTPISLSGL
                     TFFNTLFDENASNHLALGAAYAFSIKGGTEMTNDELKAAGLNRSTAHVDFMIGSEQMD
                     IDGITKDGQVIPIFRGGEWAI"
     gene            complement(12056..12769)
                     /locus_tag="TVR04_000542"
     CDS             complement(12056..12769)
                     /locus_tag="TVR04_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1269256.1"
                     /translation="MRLDKFLVDAGLGGRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAYLDILEINESLKTSLVKITIEEGKFHQVKRMVGACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELETLRS"
     gene            12934..13293
                     /locus_tag="TVR04_000543"
     CDS             12934..13293
                     /locus_tag="TVR04_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1269257.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            complement(13385..14608)
                     /locus_tag="TVR04_000544"
     CDS             complement(13385..14608)
                     /locus_tag="TVR04_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1269258.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAGKMGRISSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMLAIDDDKIIDNHVNDLEEVSQPVKISELFKTPALT
                     GQTIALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTILGMCLGMLTFG
                     HILDTYGPRLVYSVFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGSILDAYGVSMVMLFLSLLYLISFVALW
                     TIKNVKAERYQALTK"
     gene            14966..16450
                     /locus_tag="TVR04_000545"
     CDS             14966..16450
                     /locus_tag="TVR04_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1269259.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERINQFDGKLYMEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGIMSYRHYPIKGYPTDINHIISPEGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTETAVKKLELLMND
                     IGVTPKDRQVTLIARQKAELTGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNSQADLAMKE
                     LENLRGSEAHSTVILTNEDKHVLRQLGVNVTFDPVYQHHKLYRS"
     gene            complement(16506..16910)
                     /locus_tag="TVR04_000546"
     CDS             complement(16506..16910)
                     /locus_tag="TVR04_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1269260.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTKVSLTMFVTGEKRSSD"
     gene            complement(17773..18309)
                     /locus_tag="TVR04_000547"
     CDS             complement(17773..18309)
                     /locus_tag="TVR04_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269261.1"
                     /translation="MLSLLVGGLMAVKLLTERLIIQELNETYFELYHKAFTEEITAFQ
                     WPDPFKDIASANETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKDKYRYFNYEVDIRNTGSIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            complement(18495..19142)
                     /locus_tag="TVR04_000548"
     CDS             complement(18495..19142)
                     /locus_tag="TVR04_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1269262.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPKDFI
                     GGNLQQIWDKVLAEQVTANEARDVAAAYEDYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKAAQALGLAKE
                     ELVVIEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADQCIDSIKQLCELLRSGS"
     gene            19361..19732
                     /locus_tag="TVR04_000549"
     CDS             19361..19732
                     /locus_tag="TVR04_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269263.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLLLSFDSSWLYWLTII
                     GLSSIIASYLVPRFKWVVTQS"
     gene            complement(19908..22496)
                     /gene="hylB"
                     /locus_tag="TVR04_000550"
     CDS             complement(19908..22496)
                     /gene="hylB"
                     /locus_tag="TVR04_000550"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1269264.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     SQGKTLLEVLDQEGQRVATVPVEILAAEDPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVSKNLADLIKDQSSTYLWSDLADLHQSSQMTATCRRLEEMARQVSSLASK
                     YYQDKELIRLIKDKLAWLTLNYYHLQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRSTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYILFINGQETALTEEVLHRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQAHSQASDSYAYILLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQDLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(23139..23768)
                     /locus_tag="TVR04_000551"
     CDS             complement(23139..23768)
                     /locus_tag="TVR04_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1269265.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAVACSLAGIDGGIKTIEV
                     AYTNPFAGQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIPYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDIMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(23770..24771)
                     /locus_tag="TVR04_000552"
     CDS             complement(23770..24771)
                     /locus_tag="TVR04_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1269266.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGNVCQAQLYFGGSEVNIARTLS
                     GFGAASSLLTALPDNQVGRSFEAFLRQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKGLDYGKLFEAVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKRLFSHFAQYADLIFGMEPLMCNQADYAMFERDKADQSAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASFKCTVADDQLFVSANQVDRVMRGNREVRR"
     gene            complement(24804..25445)
                     /locus_tag="TVR04_000553"
     CDS             complement(24804..25445)
                     /locus_tag="TVR04_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1269267.1"
                     /translation="MKIALINENSQAAKNNVIYEALVSVTDKYGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREILQQ"
     gene            complement(25480..26274)
                     /locus_tag="TVR04_000554"
     CDS             complement(25480..26274)
                     /locus_tag="TVR04_000554"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1269268.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDKGVAAYREFGIEAHGYVCDVTDEVGIQEMVAQIEKEVGVIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            26580..27014
                     /locus_tag="TVR04_000555"
     CDS             26580..27014
                     /locus_tag="TVR04_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1269269.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSAVLQPKAQALVLCDLLGGTPFKVAATLMEGPSETTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQTVAKLLTTAKEGISNWKSLSIEADEAELDEGGI"
     gene            27014..28213
                     /locus_tag="TVR04_000556"
     CDS             27014..28213
                     /locus_tag="TVR04_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1269270.1"
                     /translation="MTRQIKEVTLEPLMQAEVYSQQPCLTKADIEAAILLALKQIRLN
                     MDYFGTDFPTPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGDDAIRSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGASLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            28259..28747
                     /locus_tag="TVR04_000557"
     CDS             28259..28747
                     /locus_tag="TVR04_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1269271.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKTVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            28762..29541
                     /locus_tag="TVR04_000558"
     CDS             28762..29541
                     /locus_tag="TVR04_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1269272.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKEPIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDEWI"
     gene            29528..30349
                     /locus_tag="TVR04_000559"
     CDS             29528..30349
                     /locus_tag="TVR04_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1269273.1"
                     /translation="MNGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALEDNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            30749..31750
                     /locus_tag="TVR04_000560"
     CDS             30749..31750
                     /locus_tag="TVR04_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1269274.1"
                     /translation="MQRKVTINDIADLANTSKTTVSFYLNGRFDKMSQETKSRIKAAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKHMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYHQMI
                     IDENQTSSQEIAQFLQDAFDQNRHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
     gene            32340..32606
                     /locus_tag="TVR04_000561"
     CDS             32340..32606
                     /locus_tag="TVR04_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1269275.1"
                     /translation="MSDTITSSPVAASAAISELVGVDISKVHQQSVAFSVTSGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            32618..32977
                     /locus_tag="TVR04_000562"
     CDS             32618..32977
                     /locus_tag="TVR04_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269276.1"
                     /translation="MIKEESEEKWLALTRQINELEWLEEDLLSMKRRHEQAVSELQAD
                     CRHLSFALESLLNHMSEDYAGKYAEQEANDHLIRQIDRYVDEHLDHVSTYTMGVRRRL
                     ERDQEKLIGERSRLRWE"
     gene            32968..34307
                     /locus_tag="TVR04_000563"
                     /pseudo
     CDS             32968..34307
                     /locus_tag="TVR04_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34304..34810
                     /locus_tag="TVR04_000564"
     CDS             34304..34810
                     /locus_tag="TVR04_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269277.1"
                     /translation="MKRKTYYIVAALIFFASLLFSYRNRLYYSLKGDYYLEPKSKIRL
                     KVRPKVTQIEYSSDLYLESDEKVLLKLEGRDTWHENCGWTYKNMGDIGYRYSITERVI
                     KKYDSNTDNGIIVATGHKGATIDGDGIIVPLKGKRKYSVTEDHDYSITITNLSDKPVA
                     FRAIVADR"
     gene            complement(35009..37690)
                     /locus_tag="TVR04_000565"
     CDS             complement(35009..37690)
                     /locus_tag="TVR04_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1269278.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGEIRPITEADRQTILATNKDLAKQALRVLMMAYKYTEAVPALETEV
                     IEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGLDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVAFVEFVKAIQRSLGQDDKAI"
     gene            complement(38040..38426)
                     /locus_tag="TVR04_000566"
     CDS             complement(38040..38426)
                     /locus_tag="TVR04_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1269279.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNDNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKTLIAIPTPVGIQQFLTDTSHFHLDHDQQT
                     VTLDYALLQASTETAFAHYHLEIKWY"
     gene            38507..39808
                     /locus_tag="TVR04_000567"
     CDS             38507..39808
                     /locus_tag="TVR04_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1269280.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     AVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            40033..40842
                     /gene="yidA"
                     /locus_tag="TVR04_000568"
     CDS             40033..40842
                     /gene="yidA"
                     /locus_tag="TVR04_000568"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1269281.1"
                     /translation="MSIKLVAIDIDGTLLNDDRRITNDVFEAIQEAKAQGVHIVIATG
                     RPIAGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIIKMMMIDEPD
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAISHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGSPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            40842..42056
                     /locus_tag="TVR04_000569"
     CDS             40842..42056
                     /locus_tag="TVR04_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1269282.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     LIKYDPSLFISQALIGEERTDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKIAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            42056..43291
                     /locus_tag="TVR04_000570"
     CDS             42056..43291
                     /locus_tag="TVR04_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1269283.1"
                     /translation="MALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKDIKVAAILYSVAMAGGLRMEINSGPVVADATYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLIELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALIKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKPLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLANLRHSQDKLKQRISKLEADLVKNPRSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(43500..44258)
                     /locus_tag="TVR04_000571"
     CDS             complement(43500..44258)
                     /locus_tag="TVR04_000571"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1269284.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKTIFANGLTPIICCGESLETYEAGQAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(44524..45720)
                     /gene="tuf"
                     /locus_tag="TVR04_000572"
     CDS             complement(44524..45720)
                     /gene="tuf"
                     /locus_tag="TVR04_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1269285.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT        13595 a        10708 c         9128 g        12892 t
ORIGIN      
        1 ctacccttgc ttttttgctt gcctttaaat gtgataacca agatagaaaa tcaaggctag
       61 cccttaggtt tgtcttttca taggggctag ctgcttgcat tgactaagga cgcttgcgct
      121 tagtgaggta ataccctaat ccaacaaaag ctaatcctgt cacgatatgt aggtatttgt
      181 tgccaactat tggactaatg gcaataagga aaaatcctat agccattaaa aagcttgctc
      241 cgttttttgc tgtcatgaaa ggtcactcgc tttttcttta ttagctgaaa tgacaaatgg
      301 tgcccagata agaaaggcaa caaagaggtt aaacaaggaa accagacctg ccataacact
      361 acctccagta gccaagtaag cgtaaagtcc aactggcgta atccaaggaa ctggcaagaa
      421 aacgggaggg atcaagccta ttgctgtggc agcataagca atgctagcac aaattggtgg
      481 tacgattagc catgggatag caaaggttgg gttcaagaca ataggcatac caaaggtaat
      541 tggctcattg atgttaaaca cgcccatcgg tgctgataat ttggcaatgg tcttgtgctc
      601 ctcacgtttt gagaaaataa agatagcaat aatcagagcc agagtaacac ctgaaccacc
      661 catttgtgca taggcatcaa aggagcctct cgtccagaga taaggcagat tagcaacgct
      721 ctgactggta ttataggcag ctgtattttc tgttagagcc actaagtaca caccatcaag
      781 cacgggtgct aagacattgt gaccatgcaa accaaagaac cagagcaatt gaaccaaaaa
      841 ggttaacagg ataacagagc caatcccttg agacagcccc aacaaaggca attggatata
      901 ggtcgaaatc atatcactta gagacgagcc tgtgagggca aaaataaggt aagctacgat
      961 cgctgacaca taaatcgcga ctgtccctgg aataatagcc gcaaaagcct tattaaccgc
     1021 aggtggcaca ttatctggta atttgatggt caggttacgt ttggtcaaag ccgcataaac
     1081 aaagctagat aaaaagccaa tgatcaatgc tgtaaaaaga cctgttgctc cagcatattt
     1141 gagggcaatt gctccccact ggcttgtttc tagagcttgg gctccatttg cagtgaccac
     1201 tgatagcccc atatccttta agcctgctaa taaacttgct gacgcccctt caagtggtgt
     1261 ggaaatggtt aagctttgag gaagggtggc aataaaggaa gcaaaggaga ttaaacctcc
     1321 agccaaagga ttcaccttgt gcataagagc taaatgatac ccaaaagcaa aggcaaaaaa
     1381 gagtgccatg ataccaattg tcccaaaata cacataacca ttgatgtcaa taatgggctg
     1441 catggctgtt gcaaaacggg tccagcccat attgtttgga atatcacgca agaaaacatt
     1501 cagcaagacg gcaacagagc ccgccatcgt gatgggcatt agcgaaataa aggaatcacg
     1561 aatggcaacc aaatgccgct gggaccccat ctttcccgaa atctccataa acttatcaga
     1621 aaaatgtgac ataattttct cctgtttcta ttttttagta tgacaagccc tatgatcagc
     1681 cagctgagct gtactcaaat cttcctctag cttagctgct tagcatactg gataagggct
     1741 gctaattggg cttgtgattg ccgtttgaag ctcttcttaa aaagcttccc aatgatcagc
     1801 tgattggctt tttgaaagac atcaagtggc tgatagtcgt agcaataggt tattttggta
     1861 cgctcctctc ccagagcttc taagcggtag cttaatgttt ttagcccatg attagagcta
     1921 aagcaagcag catataagtg cggagcttct aaggctgtga tcagcactct aacgttatgc
     1981 tccttgtttt tgccataatg ctttatgtag cttagccctg cttttaattc agctggtggc
     2041 agccgtctca gggtgttttc atgataatcc tcttggagag agcttagtat agccttgaag
     2101 cattgagtga cagagacatc tccttctgct gtaatcatca tcattgctca cctctttgga
     2161 tccttgatat tttgtcataa acagcgacca attccttggc caaatcaata aaggctaggg
     2221 ctgtcatcat atggtcttgg ccatgcacca gcaacaaaga caagtcaacc tgatctccag
     2281 ctgcttcctg agatagcaaa ctggtttgtg atctatgggc aacatttaaa gaatgtgtag
     2341 cctcttgaag caagtgttga gccttttcaa attgaccatc tctagctgca tgaatagctt
     2401 ctacagcctt gcccttggcc tcaccaccat acatgattag acccataatg gcctctaggt
     2461 ttgatggttg tgtcatggct attcctccat cattgctagg gctgtttcaa gcaccttgtc
     2521 accattcatg aggccatagt cagccatgtt aatgacatct accttaattg ccggttcaaa
     2581 tttggtctta aagtccttga gtaagaattt gacctgcggc cctaacatga ggacatcaat
     2641 ggttttagca gcaacctcat tgtcagcttc gctcacagga actgcccaaa tctcaacctc
     2701 gatgccacgc gcttgagcgg ctttttgcat tttagtcacc agcatactgg ttgacatgcc
     2761 ggcattacaa actaacataa tggttttcat aatacttctc cttttattca gtgatgagtg
     2821 gggtaaataa tgtgatgaat tgtgcatagc ttggttcttc taataaagcc tgctgaagct
     2881 ctgcttgatt gacaaaagac accaaactcg gtgaaatata ttttaaatag ctgttacgtc
     2941 ccttggacgg tgacaacaaa aagataaagt gaacagcccg atgactctcg tcccagtcaa
     3001 taggctcttg acagacagcc accaccacct gttcagaata ggtcatggga ttagccgggt
     3061 gtggaaaggc aagcacctca ccaaaaacaa ttgagctata attttccctc aacacgattt
     3121 ggtgataaaa ggcctcaaca aaggcttcat ccattgcttc gtcaagacaa gcaatcatct
     3181 ttaacagcaa ggccttcttt gatagttttt ctttcacata aagaaaacgc ttaggactaa
     3241 agacaccttt tagaatctgc tctgcttttt ccaagctcat ctgcgatgac gacgcagctt
     3301 ctcttcttat tccctcctgc tccccgataa attggcgaat ggctttgatg tcttgatcag
     3361 ataaaaagac actgacagta atgactggcg ttaaaaacat gacattagca aggctgatag
     3421 aagaaataat cacatcaacc gtttgcagtc gttcctgtgt tatttcatag tagctgataa
     3481 catctacaat ctgaaagcga ccttcaaatt ccttttccaa gcgatttttc agcatcatgg
     3541 cactgccata gcctgtggca caaaccacaa gcaccctgag cttgtgacga ttggaatagc
     3601 gctcaatagc tgccatgaca tgcaagctaa tgtaagccca ttcgtcatca gacaggtcat
     3661 aagcctgaag ctcaggaata ttctcaaaag cttgcttggt cagggcaaaa gcctctgggt
     3721 atttgctttt aatctcctca gttaagggat tggtcagctg aatatgattt tcaagccttg
     3781 tggctaaagg cttcatatgg gccaatagac cttgaagcaa gctgctatca gcctccaaag
     3841 acatacctgt cagctgacta gccttgacaa tacctgcttt taaatgactt ctcagcaagt
     3901 catcagcctt attgtcctgt gggctgccat caacggaatg cttaaccttg aggtgtaaag
     3961 caatatagtt agcttcttct ttaggaaaac gaatgcccat cacttcttct actcgatata
     4021 aaatacgtag agccacttga tactcgtctg attggcgaat agctgctgga atggaaaaaa
     4081 atgctaacgg atagccagac cgaatacgct gaaccattag ggcaatgtgc aaaaccaaat
     4141 tgtgcatgac aaaatcagaa agctttaatt tggcatctcg acattcatct aaaacaatta
     4201 ttgtgatatc agcaaacttg atatgatcaa gaaaggtatt gtctactatg gcgtacatgg
     4261 agtcatcaaa gctggtagca aaaaaataat ccatgataaa atgcctaata gcctcttcct
     4321 tacctgtcac ctgaacgcgc tgatgactca catcaagctg tagctggtaa ggcctaatac
     4381 ggtctctaat aaccgctaaa acatggttta gggtcgtccg actaatatac aattcttggc
     4441 agagcttctc aaaatcccaa acaggctctt caaagaagaa tttatttagc aaataatgct
     4501 ctcggtcaac tgtttcttcc acctgagtca catcagccaa gcgcttttta gaggtcaagc
     4561 tttcctgcca aaagatctca aacgccatag aatgatcaat ctctaaacag tagccttgac
     4621 cttgcttaga aatgatgtgc gctcccttac taggaaggct gctaatcagc tcctttaggt
     4681 attttctgac tgtgcgatcg ctcataccaa tagccttagc caaggtagca ctagagacaa
     4741 actgcccttt ttggctgatt agaaatgcta ctatagccat ttcttttttt gatagcatca
     4801 ttcctccttc gtattttaga aaacgctttc tttactctct tagtgtagca aatttctcct
     4861 gaaaaaagtg accatcattt tccgtatcga ttgtgaagcc agactagtca gtctcaatca
     4921 ccaatgaaaa ctcctgccag ggcttcagct cgtccagcaa gcttaagtaa tcctctttaa
     4981 tgtcagcgac cacattggcc tttgagctaa gggtaaaggc tttgagtgca atttgcaatt
     5041 ctcccttgta cctgttgtaa cggtcattat caatgataat actgcctcgc ttaacctgct
     5101 tgggctgctc tcttggagca attgcttctt gagcatatac cacacgcggc atggttgagc
     5161 gaatcacata atctgataca tctccccgat aacaatgtgg gtaacagata atcttctcct
     5221 ctatgtccgt caaatcaacc agaggcttga ccttaataga catgactgat ctatccaagg
     5281 cttgacggca ctgaacgagt tcatcttcag tgatgaattg attggacaaa atgacagtat
     5341 caatagttcc tgtcgccttc atcagttcca cctgcacgtc aattggcaaa taccgatgag
     5401 cctcaacagt cggtaagccc tctgacagcg gccaagggcc ttcctttgct gattgggctg
     5461 tgataaaagc agccgttgca atcccatgct cgtggtaaaa atgggacatt tccttaaaat
     5521 gctccagtga caggccggta aaggcgtgcg ggtaaaaatt atgacaacca atgaggttac
     5581 tccgatcagg agctgccttt agcaaggctg tcaataagct cttatcagta ctcatattga
     5641 gttcaatctt aagcccaaaa gagtttttca ttagcctaac aatatcctct aaaggcaagg
     5701 cctcatctaa acgcaagcct actaagccaa aagcatgagc ctcttcaata acctgatctg
     5761 accaaccagc ctgcttgata aaagcagggc taacgtctgc aatgacccga atgcccaagc
     5821 aattggcata agcaatcaga tccgcataaa gcttaaaggt cttgggatca tttggcgcca
     5881 actgtaagag gctcataaac aagcgcttgg ctccatagca gtgcagtaaa tcaatataag
     5941 ccttactctt agcaaaacca tgccgctcag ggtaaaggga aaatcctaag gtgaccatca
     6001 tacgctccta tttatcaaaa ccatttgtct gactcagggt cttaaaccag tggccagatt
     6061 ttttaagggt tcgtttttga gtctctaaat ccaaggctac caagccataa cgatttttat
     6121 aggcatttaa ccaagaccag caatcaataa aggtccatag gaggtagcct ttacagtttg
     6181 caccttcttc taaagcccta tgcaattgaa tcaaatggtc cttgataaag gcaatccgat
     6241 aatcgtcttg gacctgacca tcagctaaaa aggcttcttc accttctact cccataccat
     6301 tttcagtgac tagccagtca atattgccat aatgctcttt taaagtgata gcaatgtcgt
     6361 aaaggccctg ctcatatatt tcccaaccgc gatgagggtt aacctttttg cctggcatat
     6421 cataaagttc aaaataagag gctagcgtga tcggatcacc atcttgtctt attttattag
     6481 gcgcttgcac acgcaggggt tgatagtaat taacccccaa gaaatcaaca ggattgtttt
     6541 tgataatagc caattcatca gcactatact ggggcaataa atcagctgcc tctaaaagag
     6601 ctactaactc ttctgggtac actcctaaga cagacggatc taggaaggat ttagtctgga
     6661 aaagctctgc gattctcgct gccttgacat cttctggctg atcacttcta ggataggcag
     6721 gagtcacatt cagcacaata ctaatcctat gcttaggata cagctcgtgg caggccttga
     6781 tagcaagtga gctagccaac tgggtatggt aagccacttg aacagctgcc ttggcgtcta
     6841 ccttgcaagg atagtggtaa tgccccaaat aaccgcattc gactggaaca ataggttcgt
     6901 taaaggtaat ccatgtatcc accaaatcac caaaaagctc aaaacaggtc ttagcatagg
     6961 tctcataagc ccagaccgtc tccttagcct cccagcctcc cttttcttgc aaggcataag
     7021 gcagatcaaa atgatagagg ttaacaatca gcttaatgtc ctgagccatg atttcctgaa
     7081 atacctctcg gtaaaaggct acagcttttg gattaacctg accaacccct tctggaatca
     7141 gtcgagacca ttgaatagag gtccgaaaag ctgtgtgacc ggtctctttc aaaagggcaa
     7201 tatcgctttt gtagttggtg taaaaggttg aggttacctc tggaccaatc tgatgatgaa
     7261 acttatctgg ctccagacta aaccagtagt cccaattgct aggtcccttc ccatctccag
     7321 aaacagtccc ctcactttga gggccagatg ttgagcttcc ccacaaaaaa ccttctggaa
     7381 attggtaacg gcgttttgat tgcttcatat gctttttcct ttctttttgt cacttatacc
     7441 cctattatag gaagaaaaaa ggatactgta aacgctttaa aaaatctggt ttttccttat
     7501 catcaaggaa aaccactgac agagcaaagc caaggctctt agtcctttgc ttctagacaa
     7561 aacaacaagg agtattagca acagcagcca gcaaggaaac tcttaactca tttacctcta
     7621 gttaacacca tcgtctgcga gtgttatccc tcacaaccaa tcacactatg gcaggtatta
     7681 gcttattttt ccctaagtcc cagaacaaac gcatgaagaa aatcattgat tgaaaaagtt
     7741 gtgaaaagag caaaatatcc attttagagt attttgatag agtgtttcct gaatttttat
     7801 actctccctc tataaacttt tcttgaaaaa tttcttttct gcaattatca ctatgatttt
     7861 cctgtttttc agaataagtt ttcgtatgtc agaaatatct taaaaatttt ttcttcatgc
     7921 gtttgtcatg cctaagtccg acaccctatt gacagataaa aaggcctatg cttgaataag
     7981 gatatggctt atttaaacta ttttacaaaa accgagtgga cgctttggtt aacctccatt
     8041 tcggctattc tcctcagtgc ctttttcttt ggagaacaag ctcccttagc actgatagct
     8101 tccttaatcg gtgtgacagc tttaatcttt agtgccaagg caaatccgat tggacagggc
     8161 ttggccatta ttttctccct tatttatgcc tatctgtcac tattaaacag ttattacggg
     8221 gagctgataa cctatctctt catgaccctg ccgatggcta ttttgtcact gtttacctgg
     8281 ctaagccacc catttgaaga ccagacatct caggtaacca tctcacgctt gacaacagca
     8341 gaccgactgc gcctagtggt ccttaccata ctagttaccg gcttgttcta tgctatctta
     8401 gcctatctta agacagccta tctgcctgtt tctaccttat ctattgccac ctctttttca
     8461 gcagcctatt taagctacaa acgtagccct tattttgcct tggcctatgc tcttaatgat
     8521 ttggtcttaa ttctcctgtg gctctatgct gctcaagcaa ataccagcca atatgcagtg
     8581 gtcatttgtt ttgcagcctt tcttgttaat gacatttaca ccttttttaa ttggctacat
     8641 ttgcagcatc accaagaaaa aaagcatcaa aaaaggacga agccttgaag tacaccctca
     8701 aaagttagac actaaatcta acgattgaga ggaagtgcac ttaagcttca tcctttttta
     8761 atttgtcacg ttccaaacgc aaacgcctat tgggatttaa gagattaaat aattcttcta
     8821 atttttcagc attccagaca tctgctgccg aaacaaagtt accgtcctta tccttgaagg
     8881 atattggttt atctcccata aaaacctccc tagctcacat caaccaagac ctcattgctg
     8941 tgaattgagc aaacagccta cttcagatat gactcagcat cacttgctac aaaaaacagc
     9001 taagcttggt atttgtcatt agtctacaaa ttcaaactca aacttgccaa tgcgaacaat
     9061 gtcgccgtcc ttagcaccac gctcacgaag cgcttcatca acacccatgc cacgtagctg
     9121 acgggcaaat ttcatgatgg attcgtcgcg ctccagattg gtcatcacaa agagacgctc
     9181 taatttctca ccagacaata cccaagctgc atcatcagca cgactaatct caaaggcctt
     9241 ttcctcagac gcaaagccat aataggcctc gtcctcagca aaatcagcct catcatacaa
     9301 caagaaatca tcagtttttg ctaatagctc tgctgttgct tctaataggc tgtccaagcc
     9361 ctgatgtgcc agactggaaa taggaaaaat cattggcaac tcgtcaaagt catcatactg
     9421 agcagctaac tgttccttga agcgctgcag ttgctccttt gcctctggca tatccatttt
     9481 attggcgacg ataatttgcg gacgctccat aagacgaaga ttatatgctt ctaactcctt
     9541 attaatcgcc acatagtcct cataagggtc tcgtccttca gctgctgaca tatcaatcac
     9601 atgcaggatc acacgtgtac gctcaatatg gcgcaaaaac tgagtgccaa gccccacacc
     9661 ctggctagct cccttgatta gccctggaag atctgccata gcaaagctct caccagattt
     9721 ggttcgaacc atacctagat taggcacaat agtggtaaag tgataagcac caatcttggg
     9781 cttggctgat gagaccacgc ttagtagcgt tgatttacca actgacggaa aaccaaccag
     9841 tcccacatct gccaaaatct taagctctag ctctaattgg cgctcctctc ctggttcacc
     9901 attttcagca atctcaggtg ctggattgcg cggcgttgca aaacgaatgt tcccacgacc
     9961 gccacgacca cccttagcca cgacaaattc ttgaccatgc tcaaccagat ccgtcagaac
    10021 cttaccggtt tcagcatcac gcacagtcgt tccctgtggc actgagataa tcaaatcctc
    10081 tgagccacga ccatgcatgc ccttagtcat gcctttttca ccggatttgg ccttgaactt
    10141 acgattgtag cgaaagtcca ttagggtacg caaaccttca tcaaccttga aaatgacaga
    10201 gccacccttg ccaccatcac cgccccaagg gccgccatta ggcacatatt tttcacgacg
    10261 aaaggccacc ataccatcac cgccacgacc agcctgaaca ctgaccttag cagtatctaa
    10321 aaacatactc atacttttct tctcaaacct tctcttatcc taaaaaaacg cctttcagcg
    10381 ttttcttaca tcaatactga cagggcaccc gcaataagtc caccgacagt cacaagaacc
    10441 atcacgatca caacaactgt tgtcaacttt tcaaaggcag tttttttgcg aggtccattt
    10501 tctccaaatg ccactgttaa atacctcatc tattgatttt ttcctcttat atcttaacac
    10561 gaatgtcgct attaagcaaa tatctattga agcctaaagg cagcagcaaa aagaaagctt
    10621 ttttgcgata gtcaatctaa taaagcagct agtttacaaa gagaagagca gcttgtgaaa
    10681 tttccttaaa tatgttacat taaattttac aacattaaca ttttaggaga ttgctatggt
    10741 tttgccacat tttgacgaac atcttgaaaa gtatgctaac cttctgatca aaaagggggt
    10801 caatattcaa aagggacaca ccctgctgat tactattgct gtagagcacc acaagcttgc
    10861 gcgactatta accaaaaaag cctatgaggc tggtgcggct gaggttcttg ttgactataa
    10921 tgacgatcag atcacacgcg agaagcttct taaggctgat gaagaccgtc tcttgcaggt
    10981 accagattat gtcgttgaac agtcacatta tctccttgat caaaaagcaa gccgcttagt
    11041 cattcgctct gccaatccaa acgtctttgc tgatattgat tctgataggc tagctggagc
    11101 aacacgcgca acagctattg ctcttgaaaa acagcggact gccactcagg ccaacaaagt
    11161 cagctggaat ctagcagctg cagccagtcc cgaatgggct gctatggttt ttccaaaact
    11221 gacaaccgaa gaagagcagg tggacgcttt gtgggatgcc attttcaaaa tgaatcgcat
    11281 ttacgagaca gatcctgtca aggcctggga ccaacatcaa gaacgtttag aaaaaaaggc
    11341 aaaactactt aatgattatc agtttgacag ccttcactac agggcaccag gaactgatct
    11401 aaaacttgga atgcctgagc agcacatttg ggaagcggct ggcagtacca atgctcaagg
    11461 agaagtcttt atcgcaaaca tgccaactga agaggtcttt accgctcctg actatcgtcg
    11521 cgcagatggc tacgtcagct ccaccaagcc tctgtcctat gcaggtgttg tcattgagga
    11581 tatgaccttt acctttaagg acgggcaaat tgtggacgtc actgctaaaa agggagaaga
    11641 caccatcaaa cgcctgatat cagaaaacga aggagccaga tcacttggtg aggtggctct
    11701 tgtcccacat aagactccca tctctctatc tggtctgacc ttctttaata cactttttga
    11761 tgaaaatgct tcaaaccacc ttgctctcgg ggctgcctat gcctttagca tcaagggtgg
    11821 taccgagatg accaatgacg aattaaaggc tgctggccta aatcgctcaa cagctcacgt
    11881 cgactttatg attggttctg aacaaatgga tattgatggt attaccaagg acggacaggt
    11941 cattccaatc ttccgaggag gcgaatgggc aatctagtca tcttacagat cagtctagga
    12001 ctggtctttt ttactatcaa ttcagcagct aacctagcaa gtgattaatc cggctttagg
    12061 atcttaaggt ctctagctct gctgctgtta acctacgata ggctccaggc gccaaagcac
    12121 tatcaagctg taagggcccc atactaatgc gctgtaaatc actgaccgtt ttaccacagg
    12181 ctcctaccat tcgcttaacc tgatgaaatt ttccttcctc gatggtgatt ttgacaaggc
    12241 tggtttttag cgattcgtta atctcaagaa tgtccaaata tgctggcatg cattggtgat
    12301 cctttaaagt gattccctgt gcgaaatgct tgacgtcctc ttgagtcatc ataccgtcta
    12361 ccacagcaag gtattgcttg gcaacatgct ttttaggaga caaaagagca tgtgctagct
    12421 ttccatcatt ggtcactaag agcaagccat gcgtatcctt atcaagccgc ccaactggaa
    12481 agacagcctt ttgacgtgca gtatcatcta acaaatccag cactgtctta tggctagaat
    12541 cctcagtcgc agaaatcact cctttaggct tattgagcat ataatacaca aaggcctcat
    12601 aattgagcct ttgtccctga tagctaacct catcggtcat ttcattgact tgatattttg
    12661 gagacgtttg gctaacccca ttcacactaa cttgcttttt ctttaatagc agcttcactt
    12721 gactacgacc gcctaagcca gcatcaacta aaaacttatc taagcgcatg tattcccctt
    12781 cttcttactg ttagctgatg cttagcctgg cccatgcgag acacattaat tcagcaacag
    12841 ctctttcaag ctaattctta gtatagcaca aaaggcagct catttaagac tgtaagccct
    12901 taatatatta taataataaa aaaggagggt atcatgtcta tttattcaca gctatacgaa
    12961 acaaaaagca agcattctgc tcaagcaatg ggctctggtg gcttagaggt cctagcaaca
    13021 cctgctcttg tcgcctttat ggagcatgct gccttcacgt ttcttcaaag tcagctaaag
    13081 gacaagcaaa caaccgttgg aagtgaaatc gctatccagc acctagctgc ctctaaaatt
    13141 ggtcaggcag taaccattgt tatcactgca ctcaaggaag agggcagaaa atacgatttt
    13201 cgtatcgaag cctttgccaa ccataagctc attggcagag cctgccacac acgtgtcagg
    13261 gttgaccaag acgccttttt ggaaaagctt taatggtcaa aaaagcgctt aggcatttag
    13321 actaagcgct ttttgagagc tttaacaaaa cctttgctta ctaatcctac tacacttacc
    13381 agatttattt ggtcagcgct tgatatcgct ctgccttcac atttttgatc gtccatagag
    13441 ccacaaagct aataaggtac aacagggaca aaaagagcat aaccattgac accccatagg
    13501 catcaagaat gctgccaata atcaccgatg aaaagccgcc aactgcgcgt ccgacattga
    13561 ggataagatt gttagctgtt gatcgaatgt gatgaggata aagccgcgtg atcattgcac
    13621 cgtagcctgc aaacatacca ttaacgaaaa atccgacaat agcccctcca ataagcatgg
    13681 ttgacatcga attagcaaac tgaaaaagat agacacaaac agaagacaaa agcaaaaaga
    13741 cagaataaac cagtcttggt ccataggtgt ctaaaatatg accaaaagtc agcattccaa
    13801 ggcacatgcc caaaatggtt gataccatcc acagagacga atccttgaca gaaatatgta
    13861 gactagcttg gataatggtt ggcagccagt tcatcatgcc aaaataacca gcaatctgaa
    13921 ccgttgtcat caccatcaaa gcgatagttt gtcctgtcaa ggctggtgtc ttaaataact
    13981 cactgatctt taccggctga ctaacttcct ctaagtcatt gacatggtta tcaataatct
    14041 tatcatcatc aatagcaagc atcatccaaa tgactagtaa aatcggagct agcccaaaga
    14101 gaaagagacc acgccagcca agagcaggag ctagccaccc cgccaataaa gcagaaacaa
    14161 ttgatccaac ctgacctgca atcccattta gcgatgagat acgtcccatt ttcccggcag
    14221 gtacaagccc tgccataatc gcgatggcaa caccatattc accaccaacc ccaataccag
    14281 caataaagcg catgaggtat aaaaattcaa tcgtcttggt aaagtaaatc aagcctgttg
    14341 ccactgaaaa aataaggatc gtccatttga ataccttaaa tttatgatgt ctatcagcaa
    14401 gcagaccaaa gagcagaccc ccaaagagca ttcctagatt agtgatagta gctatccagc
    14461 ctccttgagt actactcact cctagatcag agataataga ggacatcgaa aaggctagaa
    14521 acataacgtt aagatcatct gttcctgaag cggcaatagc agcccaaagc gcacgcttgt
    14581 tgttcttgtc taaagacaat gctgacatga ttattctcct tttaatagta gctcactgac
    14641 taccttaatt aattgaatac cctttaagac catcaaaaaa gacctaggta caagtccatc
    14701 agtcgcattc agtctacagc aaaataagag caggctcact cctctttgtc ttgtcacttt
    14761 catgcctcac agaacatcat taaagtggta tttaattgtt cctagtataa gcaagttagt
    14821 taccattgtc aagtcatttt tgctattgcc atttaaatgg ctctgctttt tatcccccta
    14881 gctacttaga agaggctaat ttttagacaa atcattcact tctcactatt tctttgctat
    14941 aatgcttagc agaggtgaaa aataaatgaa aaacattgct tttgattcca acaagtacct
    15001 aagcctacaa aggaatcata ttctagaacg tatcaaccaa tttgacggca agctctacat
    15061 ggaatttggc ggaaaaatgc ttgaggattt tcatgctgca cgtgtcttgc ctggctatga
    15121 gcctgacaac aaaatcaagc tactaaagga gctcaaggat caggttgaga ttgtcatcac
    15181 catcaatgcc aataatatcg aacattctaa aacgcgtggt gacctaggaa tctcctacga
    15241 ccaggaagtg ctccgtttaa ttgatacctt taatgcctta gatatctatg ttggctcagt
    15301 tgtgatcacg caatacaacc atcaggcagc tgcggaccat tttcaaaagc aattagccaa
    15361 aaacggcatt atgtcttatc gtcactaccc aatcaagggc tatccaacag atattaacca
    15421 catcatttct cctgagggta tggggagaaa tgactatatc aagactagtc gtaacctgat
    15481 tgttgtcaca gctcctggtc ctggctctgg aaaattagcg acctgcatct cacagctcta
    15541 tcatgaccaa ctaaagggtg tcacatcagg ctatgcaaaa tttgaaacat ttcctgtttg
    15601 gaatcttcca ctccaccacc ctgtaaacct agcctatgag gctgccactg ctgatttaga
    15661 tgatgtgaac atgattgatc cctttcattt agaggcttac gggaaaacag cagtcaatta
    15721 caatcgtgat attgaggtct ttccagtact aaacagaacc tttgagcgta ttttaagcca
    15781 gtccccatat gcatctccaa cagatatggg cgttaatatg gtcggctttt ccattgttaa
    15841 tgaggaggct gctattgaag cctcaaagca agaaatcatt cgccgttact atcaaacctt
    15901 ggtagacttc aaagcagagc gcgtgaccga gactgcagtt aaaaagcttg agctcctaat
    15961 gaatgacatc ggtgtcactc ccaaggatcg acaggtgact ctaatcgcta ggcaaaaagc
    16021 agagctaacc ggtcagcctg ccctagccct tcagctccca aatggtcagg tcgtcactgg
    16081 taaaacatct gatttatttg gtccgactgc tgctgttatc atcaatgcta tcaaaaccct
    16141 ggcccacatt agcaaggaaa cgcacctcat tgagccagaa tatgtcaagc ccattcaagg
    16201 actcaagatt aatcacctag gcagtcacaa ccctagatta cacgccaatg aaattctaat
    16261 ggcactggct atcactgcaa tgaacaacag ccaagccgat ctagccatga aagaattaga
    16321 aaatctcagg ggcagcgaag cgcattcaac cgttatcctg accaacgagg acaagcatgt
    16381 tctcagacag cttggtgtca atgttacctt tgaccctgtt tatcagcatc ataagctcta
    16441 tcgcagctaa gatcaaacgc ccagctcaaa tcgagctgga cgttttttga tatgacttgt
    16501 atcagctagt cagaggatcg tttttccccc gttacaaaca tggtcaggct aaccttggtt
    16561 aatagtctgt catcttgatt tttgatggtg acctcaatca gctgtgtggt ccgacctcta
    16621 tgcaccagac taccttctac gactaaacgg tctcctagat gaccaggctt aagataattc
    16681 acattagctt gcagagtaac agcctcaaga cctattgatt tggccaccaa accaccaacc
    16741 tgatcacaaa gggtaaacaa aaagccccca tgtgcatttc cataatagtt caaggctgac
    16801 gcatggatct ctgttgataa cagcacatga ccagcctcaa acacatcaat atgataatgc
    16861 tcaaagacac taatcgtatt tagctttaaa tcctttggta tttctgtcat tatagtcatc
    16921 actttcttat taatatcact ttaacgacca ttatactata aagaaagccc ttagctcaac
    16981 ctcgccataa gttgtctcac gcatacgcat aaagaaaagg ataaacatcg tctttataca
    17041 tcaagtagat gtcttcaaat tccaataaca ggtccccctt ccaaaatgtc tgctcacttt
    17101 tgttggacta caattttgct aaaaggttac agctgatgtc aattttttga catcacccct
    17161 gctaaagacc tgccttatga gtcgtttgca cctagttgaa ctgacagtct taaccctttt
    17221 tgatcaagga caaatagcca gcttcttcag agcttggtgt caggagctcc ttcgccatta
    17281 gagttcttta ctagtgtgat ttttgcaagg aaatgattac aagaggctgt gagtagatcc
    17341 aattattcta accccatctg cacaaccagc tgtagctaca tctcaccatt tgttaaggct
    17401 tactctatgg cctcattgac tagctgatct tgagcaaaca aaaagcacac taaaggcaaa
    17461 ttagcatgct ttcaaaaaaa tgctaaccac aagaagtaag ctagaggctt tttatgcttt
    17521 tgatcttggc acacagatcc ctcttacttc cctcattttc aacagctgtc ctgctatctc
    17581 ttcaatgata tcttgagggt acaagctcag acagagaagc tgttttttaa acaaagccag
    17641 atctcttctt tataatacct agactgtgga ctaaaagacc acaccagaag caaatactag
    17701 agctgaaagc tgctctcaac tcacacagga cttaatgcaa aaccatgact atcacctatg
    17761 tcataccaac gattaattaa gaatgtgata aacctgtaaa caaagccttt tctttgaagc
    17821 cgtctcacat tcctgatagg tcgatgtcac cacattgaat ttctctacca acttaatgct
    17881 gccagtattt ctaatatcta cctcataatt gaaataacgg tatttgtcct tcccttttaa
    17941 ataatccaca atagctctca aggcctcata gccatagcct agtccttgac ttgatttttt
    18001 caaccatatg cccaattccg gtgtctcact atcaaggcta aagacttcca agcttccaac
    18061 gaagtcattt gctttattca aaatgactag ctctagcatg tttccttttt tcatttctgc
    18121 gataaagcta gctagtgtct cattagcaga agcgatgtcc ttaaagggat caggccattg
    18181 aaatgctgta atttcttcgg taaatgcctt gtgataaagc tcaaaatagg tctcattcaa
    18241 ctcctgtatg atcaaccttt ctgttaataa tttaactgcc attagccctc ctaccaataa
    18301 gctcaatatt acttaccatt tcaccgctta taacagcacc agacataaag cagatcaaac
    18361 gcttcagcca tcctgctgcc aaaacgagaa aaacacctat ttaggctcta tcattctaag
    18421 acagatcatt ctattgtagc gatgataagc cactttaaag cctgctatcc tttcattaat
    18481 aatcgtttgc cctatcagga gcctgaccta agcagttcac atagctgctt gatgctatca
    18541 atgcattggt ctgcctgacc ttgatcaatg ccgtaacgct tgtccttgat ggccagaacc
    18601 ttcaagccag cagccttagc tgcggcaatt cccttttgac tatcttcgat aacgacaagc
    18661 tcttctttag ctagtcccag agcctgcgca gccttgttat aaatctcagg attaggctta
    18721 ccagctgtga cgtcctcacg cgccagtgta aggtcaaaat aagccttgat atgactgctc
    18781 tctaaagcta acaaaatatc acaacgacta gagtttgagg ctaaagcaag cttaagtccc
    18841 tgccctttaa gagctttgag gcaggacttg acccctttaa acataagctc ttggtaagga
    18901 ggcttatggc acagcttata gtcctcataa gccgcagcaa catctcttgc ctcattagca
    18961 gtaacctgct ctgccaagac cttgtcccaa atctgttgaa gattaccacc aataaaatcc
    19021 ttggggctga ggtggtcaat cctaatgccc ttactcgtca aaaaggcttc acgacgtttg
    19081 agataaaaag gctccgtatc aaataaaacg ccgtccatgt caaatattat tcccttaacc
    19141 attagtgccc tccttttcct tctattctag catagatcct gcaaaagtct gctttcaaag
    19201 cagggaatag atgtaagaaa gcttattttc agatttttta cagtcgctat tctttctgct
    19261 ttttggtatc ataggctatg gtatattggt ctttcacagc atttgaatgc tagacctgac
    19321 atgattattc ttgactttta ttttagagag gattttagta atgaagctaa ggcgcaagac
    19381 acgtttgaca aagataggag cacctatgac agttaatatt ggaaaatccc acaaggttaa
    19441 gctttatccg ggtgagagta tcgatattga tctccccgat gctgaggatt atttgaccat
    19501 caagcatagc aggcaagcca agaaaatcgt aaccaatcaa gatcaggtca ctatcactga
    19561 taacccaatc aaccttatcc tgttttggtc tggtgttgtg cttgtccttg gaagtcatct
    19621 cttgcttagc tttgattcca gctggcttta ttggctaacc attattggcc ttagcagcat
    19681 tatcgctagc taccttgttc cccggtttaa atgggtggtc actcagtcct gatcagcttg
    19741 agcctaagga caagcacaag aagcttactc agattaaaac aggtcttgct ctgatacccc
    19801 gtacttcttg agtgataagg ctagatcttt ctactatcag ataacattcc cccctaagct
    19861 ctttagctca ggggggattt taacttatta ctaatgtgct tgaatggcta tgataaggcc
    19921 ttaaaagata gctgcttaaa gtcatttccc accttttgat agaggtataa gcctgatttt
    19981 tcaagactca attgaccatt aaccacctcc ttagcctgat tgtatttgac caccgccaac
    20041 aggtcttgtt tcttatcatg gatcagttga agcttactgt catttcgaag cacctcaata
    20101 cgtgcttcgc tgcacacctt gtcaaagtct gctttgctga tatttggaag taggatgtag
    20161 gcatagctat cactagcctg agaatgagcc tgactgattg tgataaagct ttgggagatg
    20221 aggtctttat tgttactatt tgtattaatc tcagaccagc agcctgactg cacctttcgt
    20281 gatagcgcta atgcggttgg cttagcaaaa aggtaaccaa tattagcttg accgtcttta
    20341 gaaagtagta aaagactggt cacatcatct cgatgcaaga cctcctctgt tagtgctgtc
    20401 tcctgcccat tgataaaaag aatgtagctg ttgtctgggt tttctttgcg ttgatcaatg
    20461 gtagtagtca ctgcctgatg tgtctgacta gtgatggcgg tgccaagaaa aacaatttgg
    20521 tcatctaaga tcgtccaaga cttcttggca ctcactgtcc tatcccaatt ttgaaaatcc
    20581 ataacagcta aagctgtttt gtctcccgcc ttgatcgctc caacaaagga cgatggcagg
    20641 gtagacatgc ctgctttttc tttggccttt tctttataat cattggttag cttttttaaa
    20701 taggctactg tcacgtcctc tcgcctgacc tctgcttccg ttgttccagc catctttaaa
    20761 ggattaacgg tcggccaaaa gtggtctgag taatgaccca aatcactgtt ataaaggtaa
    20821 aacatgccat ctcctgtata ccaaccacgt gtattttcat cgttcatggc ttcaaaattc
    20881 agagttttgt tggaatgcat ggataaagca aaggcaaaat ccttttccgc attgtagtag
    20941 gccaatttat ccatctggtt aaaaagagat aggtagctct taactggact ggcttggatt
    21001 gtggtatcct ccaagagctc tttgaatagc ttcatgtcat agtagcttga taggctctct
    21061 aaaatagtct cctgattatg gaaggccaaa acagccttga tcttaccctt gatcctgatt
    21121 ttagcttgct ctggcaatgc ctcagccagt cttagcattc ctcttagtgc ttctaaggct
    21181 gcctgccttg aggaggcatt ttcacgactg atggagcgcc cacgactcat atccatgagc
    21241 tccccatgaa ccatcaaggg caagaaggct tgctcaatcc aatgagtcat gacctctagc
    21301 ttttgctggt ctaggctagt agctaatagc tgaagtaatg gtaccagctg agacaagcca
    21361 tcaataagga cattgccata ggctccagtg taggcgacat tggtatggtc aatataagag
    21421 ccatcttcat aaaagccctc accccttgat ccctttggct gaaaagcaaa taaggtatct
    21481 agggctgcta tactgtcttg aagcgctttc ttatcatgct ttaacagagc ttcaataatc
    21541 ttcactcgtc ccatatcaac aaggttaccc ccaatggcct taaaaggatt cacaagggtt
    21601 gagcgaaatt gtctaggatt aggaacaaag tgagaaattc ctttagtata gcgcttgatc
    21661 tcctcttgag tgacataagg gtaaatgaag gctagggtat tgacaatagc tcttggggta
    21721 ccaatttcaa aatcccacca attagccttg ccttcaatat ccttttgcag atgatagtaa
    21781 ttaagtgtca gccaggccaa tttatccttg atcagtctta tcagctcctt atcctgataa
    21841 tacttagagg ctaagctgct cacctgcctt gccatttcct ccaagcgcct acaggtggct
    21901 gtcatctgag acgattgatg aagatccgcc aaatcactcc aaaggtatgt gctgctttga
    21961 tccttgatta gatcagctag atttttgctc acactgtcgt ccagtttttg gtttaatgcc
    22021 accatagctg gacttgatcg gtcaaagttt tcagccccca aaatcacctc acaccacttt
    22081 gtgatcaagg aggttgtttg agggtcctct gctgctaaaa tctcaaccgg cactgttgct
    22141 actctttgcc cctcttgatc caacacctct aaaagcgttt tcccctgaga caaaggaatc
    22201 aaaagaccat tttccacgcg cacaatgttg ctggactccg ctgcaatctg ataatgatag
    22261 tcagccattt ccatgaggta gtgcttattt aaaggcagga cgatttgctc ctctaagtaa
    22321 tgtgaagcaa tcttgatgtc atcacttggc ttatcaccag cctctctcaa agaaaggtta
    22381 tcaaagacca cctgtccatg accggcctca taaaagagct ctagcttgat ttgattaacc
    22441 tttagcttag ggatataaag cttttcttgg tgttttttct cagttcctgt tgccatcgga
    22501 gaaagccaca agcgttgctc ttttgcagca ccagaacctt gctttatttc ttcaatgata
    22561 cgcgcaaaag cctgacctgt tttatccttt gtctcaatat caaaggtcag caaatactgc
    22621 ttgtctggat tgatggcaac ggtttggtgc acacagcctc taaatctctg attgccatcg
    22681 ctagtcattg tcagcttgtt atcagagaca gcaattttag gacagccctg actcttacta
    22741 gcgtccttat aatccttcca atcatttgca gactccttgc tccaaaggct tgtactttga
    22801 tgctcttgag caggactggt ctgatcaaat tgaggatttt taagcaggtt atcacctgtg
    22861 agaatgagct gctccccaag actggattcc gtagctactg acgacgcgtc ttgagtgtct
    22921 ggggagcttt cttgagaagc ctcctcagtt tttagtggtg ctttctttac cctctgaagc
    22981 tccttggaaa tggcttttgc tgctgttttt tcttctgcta agactgttgg tgcccgaaat
    23041 aaacaagcta gtatgatact agagcaaaca gaagatgata gtttttttct ttgcttcatc
    23101 tgatacctcc ttgctttttt aatgttttat gaccgacttt aacagctact catgtaatct
    23161 gcagcccttg ctgtgattgc ctgaaattga ccctgagctg ccaattgatt aaattctcct
    23221 ccaactccca gcacctgagc acctgcggca aaccagtctg acacattggt gacagttacg
    23281 ccacctgtta ccatgatatc aacctgcggc aaaggagatt tgatggcctt aataaaggac
    23341 atgccaactg tggcacctgg aaagaccttg accatctctg cacctgattc caaggcagtc
    23401 acgacctcct caatagtcat acagcccgga atataaggaa tagcatagcg gtgacatagg
    23461 cggcttgtct gcctgctaaa gctaggagac acaataaatt gagcacccgc taaaatagct
    23521 agccttgctg tgacatcatc aagaaccgtc ccagctccaa tcaggatctc tggatcattg
    23581 ccaactgctt cacgcaggcc tgcaataacc tgaccggcaa agggattagt ataggccacc
    23641 tcaatggttt tgatcccacc atcgataccg gctaggctgc aagccactgc ttctttttta
    23701 gaagctcctc gaacgactaa ggctaattta ttggctttta gccttaacat gatttctgat
    23761 tttctcatat tatcttctta cctctcggtt tcccctcatc accctgtcaa cctgattagc
    23821 cgaaacaaag agctgatcat cagcaactgt acacttaaaa ctagctgtcg cagcagcaaa
    23881 atcaagcgca gcagcaatag cctgtcctct catcaattga tataagcagc ctgcaacaaa
    23941 ggcatcacca ctgccaactc gttgcaaaac aggcgttgat agctcaatgg agcgatgtaa
    24001 ctgcccatca taggcatagg ctaggtaatg attgattcct tggtcatcga tgtgacgttc
    24061 cgtgtgaaaa atggctttta agtgatatgc ctcatataag gcagccaagc gctccttgac
    24121 agcactttga tctgccttat ctctctcaaa catggcataa tcagcttgat tacacattaa
    24181 aggctccata ccaaagatca ggtctgcata ctgtgcaaaa tgagagaaca gcctctttgc
    24241 ctccctgact gaaatcattg agctgcgaaa attcaaatca aaggaaacac agacctgccg
    24301 cttcattgcc tcaatagcca actgctcaac caggtcctga ctgacttttc ctaaagccaa
    24361 ggtaatgcca ctaaaatgaa aatgagtaac tgcctcaaat agtttaccat aatccaggcc
    24421 ttttggcccc agtaaactaa agctagaggc agagcgatca taagcaacct gactagggcg
    24481 gcagccaaag ccattttcca aataataaat accaacccga tcaccacacc attgcacatg
    24541 ctctgtggcg acaccgcttt gcctcaaaaa ggcctcaaag cttcggccaa cctgattatc
    24601 aggaagggca gtcagcaggc tacttgctgc tccaaaacca ctaagcgttc ttgcaatatt
    24661 aacctctgag ccaccaaaat acagctgtgc ttgacagaca tttcctaatg tctgaaaatg
    24721 actgggactg atgcgaatca gcggctctcc caccaataat accttggtca taggggtatc
    24781 ctttctatag ctgcagataa gacttattgt tgaaggattt ctcttaggta gtcgacaagg
    24841 tctgatggct cggcattagc aaagaaataa tgctggaagt gctctccaga aatggtttcc
    24901 ttcaagaaat cttgatcaat ctcctttaac acctccaaca aagaacgata agtcacagcc
    24961 ttcaattcgc tcaaaattct agcgttacgt tgctctggga tggcccgctc tttgggatag
    25021 ccgcccccca tcggctcagc aaataagcgc tcaaacatca gggtcaggtt aagctctgcc
    25081 ccccaaccaa agccctttgc aaatggaata gacaaggcat tgccaccatt aatctgagca
    25141 aaaaggtagg cttctgttgg ctcactagca aagccacagg tcacacctgg aaagctattt
    25201 aaggccagca tagcacccac accagtccca cagcccgtta caacaaaatc agctgcctta
    25261 cttgtcaata aaatagaagc tagtagcccg ttttgcacat aggtcagctg actttcgccc
    25321 tccttgccat acatgccata gttaaagacc tcatagccat acttatcagt aacggagact
    25381 aaggcctcat aaataacatt gtttttagct gcttgactgt tttcattaat taatgcaatt
    25441 ttcatcttct ataatctcct ttgatgcttt tttgtttctt tacggttgtt tgccaatgta
    25501 agctaaaatg cctccatcaa cataaaggat atgcccattg acaaaattac tcgcctcact
    25561 agccaaaaaa atagctggac cagccagatc tgctggagtt ccccaacgcg ctgccggagt
    25621 cttagcaata ataaactggt caaaggggtg acgactgcca tcagcctgac gctctcttaa
    25681 aggtgctgtc tgaggcgttg caatatagcc aggcccaatg ccattgcact ggatattggc
    25741 ttctccaaat tctgaggcga tgtttttggt taacatctta agaccaccct tagctgctgc
    25801 ataagcacta accgtttcac gaccaagctc actcatcatc gaacagatat tgatgatttt
    25861 cccatgccct tttttaatca ttgaaggcag aactgccttt gaaacaataa atggcgcatt
    25921 caggtctata tctaccacct gacgaaaatc cttagccgtc atctcaagca tcggtgtccg
    25981 tttaatgata cctgcattat taacaagaat atcaataaca ccaacctcct tttcaatctg
    26041 agctaccatc tcttgaatcc ctacttcatc agtgacatca caaacatagc catgagcttc
    26101 gatgccaaac tctcgatagg ctgctactcc cttatccact aaatcctgct tgatgtcatt
    26161 aaagacgatc tttgctcctg ccatggcata ggccttagca atctcaaagc caatcccata
    26221 cgaggccccc gttatcaagg caatcttgcc ctctaaagaa aagaaatgtt ccattatttt
    26281 acctctcatt ctcaatatta agtaaacctg tttaccaaaa ctatagcaag actaatccat
    26341 tttgtcaatc attttagtaa aaacacaaaa aagctaaagt ctttcttatt gtcattattg
    26401 aggaaggccg cttagctatg tttttcttac tattacccgc tttacttctt ataaatatcc
    26461 caaaaatcag accatattga tcgcttattt tgataaaata acaaaaaagt gttgacaaac
    26521 atttttgaaa gcgctacaat gtttctaagt aaactggtaa actaaaaagg agcttattca
    26581 tgatttctat tattgttatt ggtcatgggc attttgccag tggtattgtc tcgtctttag
    26641 agttaattgc aggcaagcaa gaaggcataa ctgctattga ttttactgct gagatgactg
    26701 ctgctgatgt gcatgaacgc ttatcagcag tcttacagcc aaaggctcag gcacttgtgc
    26761 tttgtgactt attaggcggc accccattta aggtagctgc taccttgatg gaggggcctt
    26821 ctgagaccac acttgatgtc ctgtctggac tcaatctagc catgctaata gaagcagtct
    26881 ttgctaggca agagcagcta gatctagaac aaactgtcgc taagctatta accacagcta
    26941 aggaagggat cagtaattgg aagtccctct ctattgaagc tgatgaagca gagcttgatg
    27001 aaggagggat ttaatgacta gacagatcaa agaggttacc cttgagcctc tcatgcaagc
    27061 agaggtctat agccagcagc catgtctaac aaaagctgat attgaggcag ctattttatt
    27121 agcccttaag caaatccgat taaacatgga ttattttggt actgatttcc ctacgccagc
    27181 cactaaggac aattgctacc caattatgga taataccgag tggaccaatg gcttttggac
    27241 cggctgccta tggctggcct acgaatacac tggtgatgac gctattaggt cactagcaca
    27301 ggcaaatgat ctgtccttct tagaacgcgt caccaaagac attgagctgg accatcatga
    27361 tttaggattt ctttattcac cctcttgcat ggctgagtgg aagcttttaa aaacacctga
    27421 agccagacaa gcagccttaa aggcagcaga taaattgatt gagcgctatc aggaaaaagg
    27481 cggctttatt caagcctggg gacaactcgg gaaagcagaa gattaccgct taattattga
    27541 ttgtctttta aatatccagc tactcttttt tgccagtcaa gaaacaggag atgacaggta
    27601 tcgtcaaatg gctatcaatc acttttatgc ctcagccaac aacgtgattc gtgatgacgc
    27661 ttctgcttac cataccttct actttgaccc tgaaacaggt gatccaatca aaggagttac
    27721 acgccaaggc tacagtgatg actccgcctg ggccagagga caagcttggg gaatctatgg
    27781 aattcccttg acctatcgct tcttgaagga tccacagcta attgccttat ttaaaggaat
    27841 gacgcactat ttcctcaatc gcttgcccaa ggatcaggta tcctattggg atttgatctt
    27901 tggagatggc agtggtcagt ctaaggacag ctccgcaact gctattgctg tttgtggtat
    27961 tcacgagatg ttaaaacatt taccagagaa tgatcctgac aagaaagctt atcaagctgc
    28021 catgcactgt atgctcagat cattaattga tagctatgcc aacaaggaca tcaagcctgg
    28081 tgcttcactt ttacgtcatg gcgtttactc ttggcactct ggcaagggcg ttgatgaggg
    28141 aaatatctgg ggagattact actatttaga agccctgctg cgcttttaca aggactggac
    28201 cccttattgg taggctgata gcatttagcc tacaaagact attgttaaag gagatattat
    28261 gacaccacca aacattatca tgaccagagt tgatgagcgt ttgattcatg gtcaaggtca
    28321 gctatggatc aaatttttaa attgcaacac tgtcattgtg gctaatgatg ccgttgctga
    28381 agacaaaatc caacagtctc tgatgaaaac tgtcgttcca tcaagcattg ccatgcgctt
    28441 tttttccatt caaaaggtga ttgacgtgat tcacaaagca agccctgctc agacaatctt
    28501 tattgttgtt aaggatttag aagacatcaa gcgcttggtt gaaggagggg tgcctattaa
    28561 agaggtcaat cttggaaaca ttcataaaac agacgataaa atcgccatta cccaattcat
    28621 ttcgctaggc gacaaggaca aggctattat tcggacattg actcacgatc atcatattgt
    28681 ctttaacact aaaacaactc cagctggcaa tggtgcctct gaggttaata ttttagatta
    28741 tatttaagaa aggaaattga tatggatatc aatttgttac aagcactttt aatcggtctt
    28801 tggacagcct tttgtttcag cggaatgtta cttggtatct acaccaatcg ctgtatcatt
    28861 ctgtcttttg gtgtcggcat tatcttggga gatttgccaa cagcacttag catgggagct
    28921 atatctgaat tagcttatat gggatttggt gtcggtgctg gtggtactgt gccacccaac
    28981 ccaatcggac ctggtatctt tggcaccttg atggctatta ccagcgctgg taaagttact
    29041 ccagaggcgg ccttggctct ttctacacca attgccgttg ctattcaatt tcttcagacc
    29101 tttacctata ctgcctttgc cggagcacct gaaacagcta aaaaacagct tcaaaaaggc
    29161 aatattaaag gctttacatt tgctgccaat ggtaccatct gggcttttgc tgtgattggc
    29221 ttaggacttg gtttattagg cgccttgtca atggatactt tacttcattt ggttgattat
    29281 attccacctg tcctcctaaa tggattaacc gttgctggta aaatgcttcc tgctatcggt
    29341 tttgccatga ttctatctgt tatggctaaa aaagagccga ttccttttgt cttgattggt
    29401 tatgtctgtg cagcttacct gcaaattcca accatcggta ttgccatcat aggcattatc
    29461 ttcgccctaa atgaatacta caacaaacca aagcatgcaa caacagctga acaaggaggt
    29521 caacaagatg aatggatcta ataagctcac aaagcgtgat tatctgaaaa ctgctcttag
    29581 agcctttttc ctgcaaaatg gctttaacta tagcaattat caaggaatag gctatgccaa
    29641 tgtcgtttac ccagccctaa aaaagcattt tggcaatgac aaaacaggcc tttacaaagc
    29701 actagaggac aattgtgcat tttacaatac aaaccctcat ttcctacctt ttatcaccag
    29761 cctacacctg gtcatgctag aaaataatcg gcctgaagaa gaaacccgca atatcaagat
    29821 ggcactcatg ggacctctag caggcatcgg ggattccctt tcgcaatttt gtttagcacc
    29881 actcttttcg accattgctg cttccttagc aagtgacggc ctgattttgg ggccaattct
    29941 ctttttccta gccatgaata ttattctaac agctattaaa attggctctg gcctctatgg
    30001 ctacaaggtg gggacaagct ttattgataa attaagcgaa caaatggcaa ttgtatctcg
    30061 catggcaaat attgtcggag ttacagtgat tgctggtcta gctgctactt ctgttaagat
    30121 atctgttccc atcacatttg cagcaggcaa ggtcgatgct gctaatgcag cccaaaaatt
    30181 tgtgaccatt cagggaatgc tggataagat tgcaccagct cttctgccag ccctcttcac
    30241 tctcttgatg tattacctca ttaaaacgaa aaaatggaca acctataaat tagttattct
    30301 aacagttatt attggtattg ttggcagctg gttaggtgtg ttagcctagc agtcttagag
    30361 attctgttaa tcagtattgg agggtctcca ttagtgatga gcaggtctct tttctattgg
    30421 gcaaagctaa gcattgacac catcaactct cgtagcctca gtcaggtctt ttgccctgca
    30481 gagcctttaa gcacaagcct ttactgctag ctgtgaggaa ggcgtcctcc ttctactggc
    30541 ttctggcaca attaatcctt tatatctcta caagcacatg atttagcggc tgattgcgcg
    30601 ccaatcttac agaaggtcgc aacttaagaa agagtaggat catttttgac ctcttcaaag
    30661 gtcatattct tggactgaaa tattaaaaca attaccattc catatgttat aataaaacta
    30721 ctaatgatga caaaaagggg tctatgcaat gcagcgcaaa gtaaccatca atgatattgc
    30781 tgacttagct aacacttcaa aaacaactgt ttctttctac ctcaacggtc gatttgataa
    30841 aatgtctcag gagacaaaaa gccggatcaa ggcggctatt gaagccacca actacaagcc
    30901 tagcattgca gctcgcagtc tcaatgccaa ggctaccaaa ttgatcggtg tggttatcgg
    30961 tgacatcacc aatagctttt ccaaccagat tgtcaaaggt attgaaagca aggcgcaaga
    31021 atttggttat cagattatca tcggcaacag caactatgat ccttcacgtg aggacgaatt
    31081 gattgaaaaa atgcttaacc taggtgtaga tggttttatc attcaaccaa cctctaactt
    31141 tagaaagtat tcacgcatca tcgaagtgaa aaaaaagcac atggttttct ttgacagtca
    31201 gctctatgag catcgtacaa actgggtcaa gaccaacaat tatgacgctg tttatgacac
    31261 cattcagcaa tgcatcacca aaggctatca aagctttatc atggttactg gcaatcctaa
    31321 tttgctgagc acacgcatcg agcgtgcctc tggttttatt gatgttttag aggctaatca
    31381 gcttcaatac catcaaatga tcattgatga aaaccaaacc agctctcaag aaattgctca
    31441 gtttctacaa gacgcatttg accagaatcg tcacaatctg gtatttgtcc caaactgctg
    31501 ggctctgcct aaggttttta ctgccatgaa ggcactaaag gtgtcattgc ccgaaactgg
    31561 tctagttggc tttgataaca tcgaatggac tcgcttgtca tcaccaagta ttaccactat
    31621 tatccagcct gcttacgaag aaggggagca agcaaccagc attttgattg atgatatcga
    31681 agggcatagc aaggaagcca agcaacaaat ttttgattgt caggttaatt ggcaagaatc
    31741 aaccttttaa caggattttt ttaccttcta gaccttaaaa aatcagccat tctaataacg
    31801 atgacaaaac aacacgaggc ttaacgcttg tttgctagca taagaaaaaa cacatcaatc
    31861 agcctgaact acccggttga tgaaacaata aaccattaag caacggtctt attcctcata
    31921 ccaagaggag caaggccgtt ttgacatttt tgacaatggt cgttattgta aacgtaacgg
    31981 tagtgtatta ctgacaggct cttcaaaaaa gctgtcgtcc ttaggtcata cgaggccttc
    32041 ttttacaagc gactgctact tcttcactac tagtgtgatc ttttagccaa tttctgagaa
    32101 catcatcagt aaaatctcgc acctgctaat aatggcaagc aagctttttt gaccagcaag
    32161 ttaatcctgt atcacttgtg acttcaactc ttaactgttt gtcctttcaa gtctactata
    32221 agaggaatga cttcccaaaa aacttcgtca gttgctctta tttaggtaag agctgcaagc
    32281 acaatggcca ctatcctgtg atataatgaa agacacaatg gttataaagg agagattgta
    32341 tgagtgatac catcacatca agccctgtgg ctgcctctgc cgctattagt gaattggtag
    32401 gcgtagacat cagtaaggtt caccaacagt ccgttgcatt tagtgtgacc agcggtattg
    32461 caggaatgga aaagggacgt caagtctcta atcaactgct acaggctgtc agcgacttta
    32521 gtcaggcagt ccttattcag gccaataaat ttcctcagct tgcggccaaa ttagagaaaa
    32581 gagacctaga ggaagcaaca agatagggga ataagtcatg atcaaagaag aatctgaaga
    32641 aaaatggctt gccctaaccc gacagatcaa tgagctggag tggctagagg aggatctttt
    32701 gtcgatgaaa cgacgacatg aacaagcagt ctcggagctc caagcagact gtcggcacct
    32761 ctcttttgcc cttgagtccc tattgaacca tatgtctgag gactatgctg gaaagtacgc
    32821 agagcaagag gccaatgacc acttgatcag acaaatagat cgctatgttg atgagcatct
    32881 ggatcacgtg tcaacctata cgatgggggt tcgtcgtaga ctagagaggg accaagaaaa
    32941 gcttatcggt gaaaggagcc gtttacgatg ggagtaacct acagtgcagc agagtcaaag
    33001 gccttgattc aagctatgac aaacaatatc caaatagcca atgagataac ggacaggtta
    33061 tcaagtggtt gtgaccatct cattgctagt ctggattcgg gagagctaca gggagcagct
    33121 tacacagcag gtaggggact ttttacagcg atcatcattc cctctatcaa aaagctacaa
    33181 gcagcgattg atgctattca ggtggagttg accacctatc aaagggcaga tgctcagatt
    33241 gccagatacg gaaccttgga tcgtgatcac ttaaccgagc taaagaggct aagagaacgg
    33301 caattgcaag tgatccaagc acagattgat gaaaacgaat cgtttatgaa gcaggtcagt
    33361 agtcttttaa ccggagacta tggcactctt tggtctgata cctctacact ataccatgcc
    33421 aaaaaccagc tggaaatagg gattcgagag gttacgacca aattggaaag ccttgaatgg
    33481 tttctaactc aaacctcaga ctgctttagg gacagcttag ttgttttgca gttagccatt
    33541 cagggagcaa cacagctcag tcaggtcttc atgagtagcg acggcagcta ctcgactgcc
    33601 ggcctagata tgagctgggt gactagcctg aggaatcaag agattagccc tgtcaatgcc
    33661 tcaaagtaca ctcaaaacca ttatcataac atactgactc ggaccattaa agccatcaaa
    33721 agcagctctg aaaggccact acaaaaatca gagcgacttg tagctgccta tgaggattac
    33781 ctctattttc tcaataagcc agcctttgat gaccagagga agaactcgga aaaaaattac
    33841 aatcatcggg tattaatttt cgtttgattg tcaacaagat gggagatgat atcctatctg
    33901 tgaatgtcaa tgctccctac ctttcacagg tagctggaag tcaattaagt gctgcaatac
    33961 ttgacaacaa acacttttat gaccttgtca atacgggtca gcccttggat ttgaaatcaa
    34021 gaacttatca tggccataac tattctgtct ggtcaagaca gtgggaatca gaattgccag
    34081 gtgactatgc tggcaactac ctctatggct atgttggtac aggcttttta gatgcttcag
    34141 ggacttattt aaaaacggca gctgggattg cccaggtctt ttctgataag gatataccaa
    34201 agtggttaaa gaacttatca tcaggtcact atggagacaa tgagggtgat actcaaatga
    34261 tccaagcagg tatagatggt tatatgaaaa ggaagaagtc aaaatgaagc gaaaaacgta
    34321 ctatattgtt gcagcactaa tcttttttgc cagtttatta tttagttaca gaaatagact
    34381 ctattattcc ttaaaaggag attattattt agaaccaaag tcgaaaattc gcctaaaagt
    34441 gcgacctaaa gtcacacaaa tagaatattc ctctgaccta tacctagaaa gcgacgaaaa
    34501 agtgctactg aagctagaag gtcgtgatac atggcacgaa aattgtggtt ggacatataa
    34561 gaatatggga gatataggat atcggtattc tataacagag cgtgttatta aaaaatacga
    34621 ctccaataca gataatggca taatcgtagc cactggacac aagggagcta ctattgatgg
    34681 agatggcatc atcgttccct tgaaggggaa gagaaaatat agtgtgacag aagatcatga
    34741 ctatagtatc accattacca acctatccga taagccggtt gcttttagag caatagtagc
    34801 agataggtag tatgtgcgca tgaactgctt taggtttttc tgttattgat tttagatttt
    34861 tgttaggcat agaaaagctc cccttatagc ttctagtgat ggtttcttgg gtcactgttt
    34921 gctatagggg gagtctatta ttttataact atggacgtca gaccattttg ttagtttgaa
    34981 agtgttctta tctttttgct aatgacgctt aaatcgcttt gtcatcttga ccaagtgagc
    35041 gctgaatagc cttgacaaac tcaacaaacg caaccatcaa gagacttcca acaataacaa
    35101 ctagccattg tgtaagggtc aaatgagtca catgaaagaa tttgttaaag ccagggacaa
    35161 caactgtagc catcaaggca acaaaggcca ctgggataga atagttaaat aatttattct
    35221 taaataatcc aactgtaaag atagactgat aaacagactt aacattataa gcatgcacca
    35281 gctgaatgag accaagtgtt acataagcca tcgttaaagc atcggcatgc acgtcatggt
    35341 agcttgtatg ctctgggaac atcaaggcaa agccataaac accaagcact aggattgtct
    35401 gaagggcacc ctgatacaga atagcttctt ttacaccacc gtcaaagaag cttgattggc
    35461 gtccacgagg cttgtgcttc atgacaccag gctcagcagg ctcaacacca agagcgatcg
    35521 ctggcagcgt atctgttacc agattaatcc aaagcaggtg aaccggctga agcacgtccc
    35581 aaccaaacaa agtggcaaga aagatcgtaa agacctcagc catgttggca gaaagcaggt
    35641 actgaattgt tttttgaatg tttgaaaaga ccttacgtcc ttcctcaacg gcaacgataa
    35701 tggttgcaaa gttatcatcg gcaaggacca tatcagaagc tcctttagaa acctctgtac
    35761 ctgtaatccc cataccaata ccaatatcag ctgttttaag agatggcgca tcattgacac
    35821 catcaccagt catggcaaca accttgcctt cattttgcca agccttaacg atacggactt
    35881 tatgctctgg agatacacgc gcataaacag aatattgtct aaagaccttt tggaaggctt
    35941 catcagacag ctcattgagc tcagctcctg taaagacatg gtctaagccg tcctcttcaa
    36001 tgataccaag acgcttggca atagcctctg ccgtatcctg gtgatcacct gtaatcatga
    36061 tcggacgaat accagcctcc ttagccacct taacagcctg agccgcttca ggacgctctg
    36121 ggtcaatcat cccaacaaga cctgagaaga taagctctgc ttcgatcacc tctgtttcaa
    36181 gtgctggaac cgcttctgtg tatttgtaag ccatcatcaa gacacgaagg gcttgcttag
    36241 ccagatcctt attagtagcc agaatcgttt gcctatcagc ctctgtaatc ggacgaatct
    36301 ctccattttc ttcgatttga gtgacacgct tcaacaattg gtcaggagcc cccttaacag
    36361 cgatgaagta tctgccgtca gcttgcttgt gaatggttga catcagctta cgatcagaat
    36421 caaatggtaa ttctgccaca cgaggttctg aaacaagagc ctcacgcaca tcaaagcgat
    36481 gatctaagcc aaattgcacc aaggcagtct ctgtaggatc accaatcagc ttacctgctg
    36541 gatcaacctt agtatcattg gcaaaattca tcacacgaag ggtattgttg tcaaaggcaa
    36601 tatcagctga tgactcttga agtgctccgt tggtataaac cttttcaact gtcatctggt
    36661 tcatggttaa ggtaccagtt ttatctgatg cgatgatttc agttgaacca agggtttcga
    36721 cggcaggcaa tttacggata atagcgttac gctttgctag tacctgtgtt ccaagagaaa
    36781 gcacaaccgt aacaatagct ggaagaccct ctggaatggc agcaaccgca agcgccactg
    36841 atgtcatcaa gccttcaagt gggcgctgac cacgtaaaaa gacaccgaca gcaaaggtca
    36901 cagctgcaat cacaagaata gcataggtta aaatcttaga tagattgtca aggttttgct
    36961 ttagcggtgt gtctgtctca tcagcattag ccagcatgcc agcgatatgg cctacctcag
    37021 tgtacatacc agtgtttgtg acaactccca taccgcgtcc ataagtaacg tttgagtttt
    37081 gatagcccat gttaacacga tcaccaatac cagcatcggc agaaacctct cttgacaggt
    37141 ccttttcaac tggaactgac tcaccggtaa gagcagcttc ttcaatcttc aaggaattga
    37201 cctctaacag acgcatatca gctggcacca catcacctgc ctcaagcagg acaatatcgc
    37261 ctggaacaag ctctttagag tcaacctcaa tcacatggcc atcacgacgc acacgcgcca
    37321 atggactaga catggatttt aaggcttcaa tcgctgcttc ggcctgccct tcctgataaa
    37381 ccccgaaggc tgcatttagg ataacaacag ctaaaataat gatggcatct gtcaggccct
    37441 ccatcccttc tgttaccaca gaaagaaagg ccgctgcaac caaaataata atcatcaaat
    37501 ccttaaactg atcaaggaat ttcatgaaca ggctgcgctt ttcaccctcg tcaagctcat
    37561 tacgcccata agctgctagg cgctgctgtg cctctgtact cgttagcccc ttacgactag
    37621 actctaattg agctaatact gtttcttcac tttgcgtata gaacgcttca tgtctttgtt
    37681 ctttcgacaa attggtccct ccctggtctt tttatgcttt attcaactaa aaagacctgt
    37741 ttatttttct taaacaagtc tcgctgtttc agattgtacc ggaaatcgaa attccgtatt
    37801 gacgacacaa tcacggctaa ccgtctgcta ctcccttgat atagtcacta ttataataaa
    37861 atgatgacca aaaaacaaga aaaaaacagg gaaatatttt ttaaaagcct caaatcatct
    37921 gatgattttc agataaaagg gcaactaata gccaagctta ggctgtcatt gccgagatac
    37981 aaacagcaga aaccggctgt cagcttagga gactagcaaa gaacttcctc ttgctaagat
    38041 caataccact tgatctccaa atgataatga gcaaaggccg tctcagtgct ggcctgtaat
    38101 aaagcataat ctagggtcac tgtctgctgg tcatggtcca agtgaaaatg gctcgtatct
    38161 gtcaaaaatt gctggatccc tacaggcgtc ggaatagcga tcaaggtttt tttgtttgca
    38221 agaaacctca tcacagactg aggctttgaa aagcgactca tcgttagctc agcagcattg
    38281 aacttaatca ctaccctttc gttgtcatta ttttgataaa ttagataggt agcatctgcc
    38341 ttttgtctca aatccccagt atgaatctcc ttgattagct ctgtttcctg accatagctg
    38401 atcttgttat taatttcaat cttcatgata tcttctttct cttgagtttt gctcgtctat
    38461 tctaccaatt tctgaccatt ttcgcaattt ctgctataat agaagcatga atgaaaaagt
    38521 atttcgtgac cctgttcaca actatatcca cgttaatcat cagctcattt acgagctaat
    38581 caatacaaag gaatttcaac gactaaggcg aattaagcag gtgccaacaa cagcctttac
    38641 ctttcatggt gccgagcata gccgcttttc acactgtctt ggtgtctatg agattgctcg
    38701 tcgtgtcaca gagatttttg aagaaaagta tgcagacctt tggcataagg aggagagtct
    38761 tgtaaccatg actgctgcgc tcttgcatga tattggtcat ggcgcttact cgcacacctt
    38821 tgagacccta tttgatactg atcacgaggc tgttactcaa gacatcatta ccagtccaga
    38881 aacggagatt aatgcgattt tgacgcgcta ctctcctgat tttcctgaca aggtagctag
    38941 tgttatcaac cacacttacc ccaataaaca ggtagtgcag ctgatctcta gccaaatcga
    39001 ctgcgatcgc atggattatc tgctgcgcga ctcttacttt tctgcggcta attatgggca
    39061 atttgaccta atgcgcattc ttagggttat tcgacctgtg aaagatggca tagcttttga
    39121 tctcagcggt atgcatgccg tagaggatta cattgtcagc cgctttcaaa tgtatatgca
    39181 ggtttatttt caccctgcca gtcgagccgt cgagctgatc ctacaaaact tgctgaagcg
    39241 tgctaaggct ctctatccta gccagcagga ctatttccaa aagacagccc ctggtctcat
    39301 tccatttttt gaaaaaagct tcacgcttgc tgattatctt tgcttagatg atggtgtgct
    39361 caatacctat ttccagcaat ggattactag tgaggaccat atcctgtcag acctgtctag
    39421 tcggtttatc aatcgaaaaa ttttaaaatc tgtcaccttt gaccaagaat cacaacaaga
    39481 tttagagcgt ttgcgaaagc tggttgaggc agttggtttt gatcctgatt attatacagg
    39541 tatccatgtc aattttgacc ttccttatga tatttaccgt cctgagctgg aaaatccaag
    39601 aacccaaatt gaaatgattc aaaaagatgg cagcagggct gagctatccc agctctctgc
    39661 gattgtcaaa gctctcacag gcacaagcta tggtgataga cgcttttatt tcccaaagga
    39721 aatgttagag cttgatgacc tctttacatc agataaggaa gcctttatca gctatatctc
    39781 taacggacac tttcatttta acaactaagg accagccaag ggccttttgg ctttttcatc
    39841 acgctctaga tttaaaatgg tatattaccc gataaggaca gctagagctc tgacaagcac
    39901 aagccatcaa acacagcagg gcctttgata ttgccaaaat ctcttttgtt ttcatgacaa
    39961 aagaacctat ttttagtaag atagaagata gcaaatcatt gactacagat cagaacaacc
    40021 aaggagaatt ccatgtctat caaacttgtt gccattgata ttgatggcac cttacttaat
    40081 gacgatcgac gcattactaa tgacgttttt gaagccatac aggaggccaa ggcccaagga
    40141 gtgcatatcg tcattgctac gggacgcccc attgctgggg tcatctcatt attagagcaa
    40201 ttgcaactaa atcaaaaggg agaccatgtc atcaccttca acggcggact gattcaggac
    40261 actgcgaccg gtgaagaggt ggtcaaagag ctgatgacct acgatgatta ccttgatata
    40321 gaatatttaa gccgcaggct aggcgttcac atgcatgcca tcacaacaga gggcatctat
    40381 actgctaacc gaaatatcgg taaatacact gtacgagaag caaggcttgt ggacatgcct
    40441 gttttttacc gcacacctga ggagatggcg gacaaagaga tcatcaaaat gatgatgatt
    40501 gatgagccag accttttaga tgaggccatc aaacagattc ctcaagcctt ctatgacacc
    40561 tacaatattg tcaaatcaac acctttttat ctcgaattaa caccaaagac tgtcagcaag
    40621 ggcactgcta ttagtcacct tgccaaaaag cttggcattg acatgtccca gacgatggca
    40681 atcggcgatg ctgaaaacga tcgagccatg cttgaagcgg ttgctaaccc tgttgttatg
    40741 gaaaatgggt ctcccgagct gaaaaagctg gccaaataca tcaccaaatc aaacaatgac
    40801 agcggcgtag cgcatgctat tcggaagtgg gtattaaact aatgtataca tataaaatcg
    40861 gaatttcagc taaagagcac gatcagtttg tcctatcaca tcctcaggtc aatctgctgc
    40921 aaagcgctca ttgggctcag gtaaaggata actgggagca tgagctcatt ggcttttacc
    40981 aagatgacaa gcaagtcgct gctgctgctt gtctgatcaa gagactgcct ctaggcatga
    41041 ccatgattta cattcctcga gggccaatta tggattattc tgactttgag ttggttaact
    41101 tcgtcatgac tagcctaaag gcttacggta aatccaagcg agccctcttg attaaatacg
    41161 atccttcctt gtttatcagt caggccttaa taggtgagga aagaacagac aatgacttta
    41221 ccctctccac tattgacttt ttaaagacca tcggtgttga gtgggctggc aggaccaagg
    41281 aacttgagca aacgattcag ccccgctttc aggccaatat ttatgccaag gactttaagc
    41341 tccaaagctt atcaaaaaag gccagacagt ctatccgaac tgctcaaaat aagggagtcg
    41401 agattattat tggctcaaca gagctgcttg aagacttctc agcactgatg aaaaagaccg
    41461 aggagcgcaa acacatttct ttgcgcggca tttcctatta tgacaaatta atgaccactt
    41521 acgctaatca ggcttacatt accatggcta gattgaatct tcccaagcaa aaagcgctca
    41581 tacagcagca attagaggaa gccttgagca atcagcaggc ctttacccag cacagtaagc
    41641 caggtaagat cgcagaaaac caaaatacca ttaaaaggct tgaaaaggaa ttggcttttc
    41701 tagataagga aatacaagca ggtaaaagcc ttgtacctct agcagctacc ctgacactga
    41761 tctatggaca gacctctgaa aacctatacg caggtatgga taatgacttt cgccaatatc
    41821 aggcagctct cttaacctgg tatcataccg cagaggaggc ctttaagcgc ggttgtcaat
    41881 ggcacaattt aggaggcgtt gaaaaccaat tagatggcgg actgtttcag tttaaagcaa
    41941 gattaaaccc agctatcgaa gaatttgcag gagaattcag cattccagtt ggacctatct
    42001 caaaagtggc catgatagcc tataatctga gaaaaaaact aaggagtaac ccttaatggc
    42061 tttagatatc attgacaaag aaacctttgg ctcattttgc agtcaagtgg agtataaatc
    42121 cttcattcaa tccatagaaa tggcagagct gctgcaaaag cgtggctatc aaacacaata
    42181 ccttgcaatc agtgaccaga aagatattaa ggttgcagcc attctctaca gtgtagcaat
    42241 ggccggcggc ttacgcatgg aaatcaactc aggtcccgta gtggctgatg caacctacac
    42301 aacagccttt tacaaagccc tacaggacta tgccaaacag cagggagcac ttgagctagt
    42361 catcaagccc tacgatacct atcagacctt taccagcgat ggtcacccaa acgatgatga
    42421 aaagccagag ctgatcaaga ccttgataga gctcaatttt acacatgatg gtctgctaac
    42481 aggctaccat aatggtgaag gagattggca ttatgttaaa gatttaagcg gattgacctc
    42541 tgctaatgtc atcaattcct tcagtaaaaa gggcaaggcc ttgataaaaa aggccaaaac
    42601 cttcggcatt aagctacata agctcaatcg tgatgagcta acacaattca aggaaattac
    42661 tgctgctaca tctagtcgaa gagattatac cgacaagcct ttatcttatt atcaggattt
    42721 ctatgatagc tttggggata gctgtgaatt tatggttgca accctcaatt ttgatgacta
    42781 cctcgccaac ctaaggcaca gtcaagacaa gctaaagcag cgcattagca aattagaggc
    42841 agacctagtt aaaaacccaa gatcagaaaa aaaacaaaat cagctgcgag aactctccag
    42901 ccaatttgat acctttcaag ttcggatagc tgaagcacag gagttaattg tcaagtatgg
    42961 caaaaaggac attcctctag ctggtagtct ctttgtttac accccgcagg aggctgtcta
    43021 tctcttttct ggctcctatc cagaatttaa caggttctac gcgccagccc tattacagga
    43081 acatgtcatg ctaagagcga ttgaaaagaa aatcagctgc tataattttc ttggtatcat
    43141 gggcgaattt gatggctctg atggtgtttt acgctttaag caaaacttta acggctatat
    43201 cacacgaaag atgggaacct ttaggtatta tccaaagccc ttcaagtaca aagccataca
    43261 ggccatcaag acaatgcttg gtcgcagcta agtcaagcta gtcgctaagc agccctttta
    43321 gccttccaat ggctattgac cacaataata aatccttgat tgtcttactc agaacccctt
    43381 tagcaaacct tccaacctaa aaacaaggta taggtgatcc catgctcaag aaggctatca
    43441 agcaaaccaa aagctcaagg aattaaccct tgagcttttt agctatatta taattgtcat
    43501 tagttgacaa aatcaagcaa ggcaaggaag ctatctgctt ctagtgatgc accaccgaca
    43561 agagctccgt caacatctgg acaagccatg tactccttaa tgttttcagg cttcacagaa
    43621 ccaccatact gtacacgaac cttgtctgcc acctcttgac caaagtcagc agcaaccaca
    43681 tcgcgaacag ccttacacat gctttgagca tcttcttgag tggcagattt accagtaccg
    43741 atagcccaga ttggctcata tgccaatacc aatgaagcaa cctgctcagc agatagcccc
    43801 tctagagctg cggacacctg tgcaccaaca aaggctactg cctgaccagc ctcataggtc
    43861 tcaagagact caccacagca gataattggt gttaagccat tagcaaagat ggtttttgct
    43921 tttttattga tatcctcatc agtttcgtgg aaatagtcac gacgttcaga gtgaccaatc
    43981 accacatagt cagctcccat ttcagcaaga accttcggag aggtttcgcc tgtataagcg
    44041 cctgaatttt caaaataaca gttttgcgca gcaaccttaa ggacagagtc cttagcagcc
    44101 tcaattgtag tgaccaaatc aacagctggt gctgctactg caacgtcaac aagatcgttt
    44161 gaaggtaatt tgcttactac tgcctcaaca aaggcttttg cctcttgagg atttttgttc
    44221 attttccagt taccggcaat aattggttta cgtgacattt cacatacctc ttcttttttt
    44281 atttacatct actattctag cacaatttct atgctaataa aagaaaatgg ctgactttta
    44341 ggaatatttt cacaaagaaa agggcatttt ctgaaactat tttcaaacga taaggcttat
    44401 ctattagcta agtagactcg ctaagtcctc atcttgataa acagagcaaa aagagcccct
    44461 aaagtagggg ctctcacaat taagctgtct gactttaatc gttatctggg aacttaatca
    44521 aaattaagct tcgatttctg aaacgatacc tgaaccaaca gtacgtccac cttcacgaat
    44581 tgagaatgta gtaccttgtt ctacggcgat tgggtggatc aactcaacgt caatagtcac
    44641 gttatcacca ggcataacca tttctgtacc tgctggaagc tcgattgaac ctgttacgtc
    44701 agtagtacgg aagtagaatt gtggacgata gttgttgaag aatggtgtgt gacgtccacc
    44761 ttcttcttta gtaaggatgt atacttcacc tttgaattta gtgtgtgggt tgatagaacc
    44821 tggcttagca ataacttgac cacgttcaat ttcatcacgt tgtacaccac gaagaagaac
    44881 accaacgttg tctcctgcaa gaccttcatc aagctgttta cggaacattt ctacaccagt
    44941 aacaactgct tttttgatct cgtctctgat accaacgatt tcgatttcgt cgttaacacg
    45001 aacagtaccg cggtcgatac gtcctgaagc aacagtacca cgtccagtga ttgagaatac
    45061 gtcctcgact ggaagaagca atggcttgtc tgtgtcacgt tctggttctg gaatgtatga
    45121 atcaacagta tccatcaatt ccatgatgat atcttcgtat ttgctgtcgc cttcaagagc
    45181 cttaagcgct gaaccttgga taactggaag gtcatcacct gggaaatcgt attctgaaag
    45241 aaggtcacga atttccattt caacaagctc aagcaattct tcatcgtcaa caaggtcaac
    45301 cttattcatg aacacgataa ggtgcttaac accaacctga cgtgaaagaa ggatgtgctc
    45361 acgagtttgt ggcattggtc cgtcagttga agcaactaca aggatagctc cgtccatttg
    45421 agcggcacca gtgatcatgt ttttaacgta gtccgcgtgt cctggtgcgt cgatgtgcgc
    45481 atagtgacgt gtagcagttt cgtactcaac gtgtgcagta ttgatagtga ttccgcgttc
    45541 gcgttcttct ggagcagcat cgattgaagc gtagtctttt ggttggttaa ctgagcttgg
    45601 tagacgacgt gcaagaacag ttgtgattgc agctgttaaa gtagttttac catggtcaac
    45661 gtgtccaatt gtaccaatgt taacgtgggg tttactacga tcgtattttt cttttgccat
    45721 tttaggaaaa gcctccaata aaatatattt tatagataga cggtaggcaa tacagtctaa
    45781 ctttacctta ctattgtagc aaattataag gaaattgcaa gcagtaagtg aggaacttta
    45841 acggatttat cgttatccct aatttcagca accttggcat acaaaaaaga aaagcgtttt
    45901 cgtcctctct cagacattcc gctctttatc gttttttgct tcccaaagct ttaggcactt
    45961 acatgctttg ggagaagagt tgaattgtta agagagaatg cactccgaga tccgtaaagc
    46021 ataggcagga catgccgatc caagactaag atagtggagg cttgagagtc cacgacagat
    46081 gcgcgaaaca gttatttccg aatgataata tagatgagag tagacacttt caacgttctt
    46141 cctatagtaa aagctatgca aaatcctaca tattcttgaa atagctgaac attgaaatac
    46201 aggaagcttt attttcttgc taaaaatttt tcatgcgttt gtcttagtta atggtcacag
    46261 agctagcttg ttagtttttt atccttttca tcatatttta tgaattttac agtctattta
    46321 act
//
LOCUS       DARYSY010000012        45395 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYSY010000012 DARYSY010000000
VERSION     DARYSY010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45395
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(284..2074)
                     /locus_tag="TVR04_000573"
     CDS             complement(284..2074)
                     /locus_tag="TVR04_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1269286.1"
                     /translation="MTHLVDLRKKPYNLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGANVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMALINTPESQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKDLLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(2198..3001)
                     /locus_tag="TVR04_000574"
     CDS             complement(2198..3001)
                     /locus_tag="TVR04_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1269287.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQV
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEFAGVSGIDALKKWVQETPSLSNQSLEAEL
                     VKQPSDDLQRALDWSNEVNRQIEAYKGEALAFPGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVSKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(3267..4106)
                     /locus_tag="TVR04_000575"
     CDS             complement(3267..4106)
                     /locus_tag="TVR04_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1269288.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIARAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFYDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(4121..5215)
                     /locus_tag="TVR04_000576"
     CDS             complement(4121..5215)
                     /locus_tag="TVR04_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1269289.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRTVEATGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDSSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQIKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGITVKTVGDK"
     gene            complement(5470..6867)
                     /gene="uxaC"
                     /locus_tag="TVR04_000577"
     CDS             complement(5470..6867)
                     /gene="uxaC"
                     /locus_tag="TVR04_000577"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1269290.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     AMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIAASRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDHLMTRVLEGYQPQPLEIKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTALAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNITVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGS
                     MAKDIAYNNAIQYFS"
     gene            complement(6895..7512)
                     /gene="eda"
                     /locus_tag="TVR04_000578"
     CDS             complement(6895..7512)
                     /gene="eda"
                     /locus_tag="TVR04_000578"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1269291.1"
                     /translation="MLNRLKENYFFAVIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRALSTEFEHDETVIIGAGTVMTPDLAREAIAAGASFLVSPHFSSEIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(7695..8366)
                     /locus_tag="TVR04_000579"
     CDS             complement(7695..8366)
                     /locus_tag="TVR04_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1269292.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAYDAMLLHIMTVKR
                     TAFLS"
     gene            complement(8408..10198)
                     /gene="uidA"
                     /locus_tag="TVR04_000580"
     CDS             complement(8408..10198)
                     /gene="uidA"
                     /locus_tag="TVR04_000580"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1269293.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGHHKG
                     GFTPFEVLVPEDLYQDNQIKVSVCANNILDYTSLPVGNYSEELQGDGSIKKVVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVVQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLTKGEVGLRQELLEWQSKFPEKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(10219..11247)
                     /locus_tag="TVR04_000581"
     CDS             complement(10219..11247)
                     /locus_tag="TVR04_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1269294.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVFLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGIYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFEGADWFHVSGITPALTSDLYELTYYLMTKARAEGV
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGVLDLKDQLGLNRP
                     YDNEALLEEVLAKLADTYGVKCFAFTQREMGYTNEYLLKAYLYQNGSLYQTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSHKEEQATLDIAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(11333..12877)
                     /locus_tag="TVR04_000582"
     CDS             complement(11333..12877)
                     /locus_tag="TVR04_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1269295.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVDEGIRFPLFIMVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPTFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTVLFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKAYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(13303..14562)
                     /locus_tag="TVR04_000583"
     CDS             complement(13303..14562)
                     /locus_tag="TVR04_000583"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1269296.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGESMRLMTEDQQLHGAHIYM
                     DTVSVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRAEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(14878..16083)
                     /locus_tag="TVR04_000584"
     CDS             complement(14878..16083)
                     /locus_tag="TVR04_000584"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1269297.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYKQTAAYGHMGRTDIDLPWEHLDKVSPLTE
                     AVAALSEGA"
     gene            complement(16416..18635)
                     /locus_tag="TVR04_000585"
     CDS             complement(16416..18635)
                     /locus_tag="TVR04_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1269298.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQQTNQPKTKQTAKKATK
                     KKQSKKVKKTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHDGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLA
                     KSLNIPEDSIRVEHTEEGVILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHASAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLVQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNSYLALESINVNRNKINTLALKEPNKTLKYIQADGNHFPAEELAAEQG
                     QFPQGIIKNFKVAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            19167..20108
                     /gene="birA"
                     /locus_tag="TVR04_000586"
     CDS             19167..20108
                     /gene="birA"
                     /locus_tag="TVR04_000586"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HEL1269299.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDLLLPELISQELGIPLSYNEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFPENLK
                     ERAGSLFSSKPSITRNALIIDIWKLFTTIPIKDHIKVYKESSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(20083..20286)
                     /locus_tag="TVR04_000587"
     CDS             complement(20083..20286)
                     /locus_tag="TVR04_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEL1269300.1"
                     /translation="MTIRQFMFMAFVCAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(20669..22345)
                     /gene="dnaX"
                     /locus_tag="TVR04_000588"
     CDS             complement(20669..22345)
                     /gene="dnaX"
                     /locus_tag="TVR04_000588"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1269301.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQAAICEHLAAILDKEGIAYETEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNQVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSPLFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQVTDTAIPSSLLADVDGLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKEPEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(22345..22842)
                     /locus_tag="TVR04_000589"
     CDS             complement(22345..22842)
                     /locus_tag="TVR04_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1269302.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGEAAQSGQTIIVDDVRKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLEKTAFRFDM
                     FGVED"
     gene            22978..23793
                     /locus_tag="TVR04_000590"
     CDS             22978..23793
                     /locus_tag="TVR04_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1269303.1"
                     /translation="MPLLRYKKIIATTLFMLLVFNGIEYEFLNLVSPKQTFYQSAALI
                     LSTSLLGIYLIPFSLAIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWI
                     SLIKPNIALEEWTGALTGPFVEEPIKAFAAMLVIYLLPTINLKQKLVISLISGMGFQL
                     TEDISYIANAADRSINDILPTTLARISSSPNSHWVYTGIFTMGVYLLIKKSQLFPRSL
                     QIFWMVSPLALHFIWNSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(23973..24245)
                     /locus_tag="TVR04_000591"
     CDS             complement(23973..24245)
                     /locus_tag="TVR04_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1269304.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILITLVLCYYLYQWYIL"
     gene            complement(24268..24894)
                     /gene="udk"
                     /locus_tag="TVR04_000592"
     CDS             complement(24268..24894)
                     /gene="udk"
                     /locus_tag="TVR04_000592"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1269305.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            24991..26073
                     /locus_tag="TVR04_000593"
     CDS             24991..26073
                     /locus_tag="TVR04_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1269306.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHHAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVNKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFAKVTEIYLKHQQLHQK"
     gene            complement(26343..27629)
                     /locus_tag="TVR04_000594"
     CDS             complement(26343..27629)
                     /locus_tag="TVR04_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1269307.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKHLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSHYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILLGHMSIPLASLFDVINPDF
                     LEGSDKTAYDDYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            28051..29214
                     /locus_tag="TVR04_000595"
     CDS             28051..29214
                     /locus_tag="TVR04_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1269308.1"
                     /translation="MSQKLGKQLIRTVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWSLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEANYLHSKS
                     KVKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYGGISHDKGMEASSESEAEDITDESTPAAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(29337..31955)
                     /gene="alaS"
                     /locus_tag="TVR04_000596"
     CDS             complement(29337..31955)
                     /gene="alaS"
                     /locus_tag="TVR04_000596"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1269309.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETIDSRLSVIIVDNERSEMVSEGQALLVFEQTPFYAEMGGQVA
                     DHGVIKNDKGDPVARVIDVQKAPNGQPLHTVEVLASLALNTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKIIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDTLKEIAHTLKVPQIEQLPSKVVSLS
                     EQIRDLQKEIAELKEKAAAAQAGDVFKKVQEANDLRYIASEVSVSDAGALRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(32312..33313)
                     /gene="prsA"
                     /locus_tag="TVR04_000597"
     CDS             complement(32312..33313)
                     /gene="prsA"
                     /locus_tag="TVR04_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1269310.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKKTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAVKKELTDADYKKAYESYTPEMTTQVITLDNEET
                     AKAILGEVKAEGADFVAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILTQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(33376..34083)
                     /locus_tag="TVR04_000598"
     CDS             complement(33376..34083)
                     /locus_tag="TVR04_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1269311.1"
                     /translation="MVKSYSKNANHNMRRPIVKEDIVHYMRTQQKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENVPEAEIITIDRNA
                     EMIGFAKENFAKYDNRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(34165..34803)
                     /locus_tag="TVR04_000599"
     CDS             complement(34165..34803)
                     /locus_tag="TVR04_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1269312.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLKRDGVRAIAGAVQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDTKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVQQLKAVCELL"
     gene            complement(34854..35486)
                     /locus_tag="TVR04_000600"
     CDS             complement(34854..35486)
                     /locus_tag="TVR04_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1269313.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALRLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKH
                     FIVTHKGKTTQAVLQRLGIADYFTEVITAACGFKRKPNPEALLFLIDKYQMAKAKTYY
                     IGDRPLDLAAARAAGICSINLLLPDSDDNHHISQLSDIAELFSGKNSSSN"
     gene            complement(35476..36033)
                     /locus_tag="TVR04_000601"
     CDS             complement(35476..36033)
                     /locus_tag="TVR04_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269314.1"
                     /translation="MKEIRTIALADQAAFERFQDILLAEKASGNTFVETQKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATVGGHIGYVTRT
                     DYRGQGIMTALLAFALEQYQKRGIKRVLITANKDNIASRKTIEKAGGILEDIIQVADD
                     YPTKRMAGQAIARYWIDLGGRDSDG"
     gene            complement(36233..38035)
                     /gene="pepF"
                     /locus_tag="TVR04_000602"
     CDS             complement(36233..38035)
                     /gene="pepF"
                     /locus_tag="TVR04_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1269315.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKLYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMDLTQETYQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRTVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVEDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNKLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL"
     gene            complement(38025..39002)
                     /locus_tag="TVR04_000603"
     CDS             complement(38025..39002)
                     /locus_tag="TVR04_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1269316.1"
                     /translation="MLTALDQDQRVISLTEGCLPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKAVLYRSLSRSEAAEVEAYLPDLNQIADLLVNK
                     RLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLKYMIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQ
                     LQMDKHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSSGFC
                     QIHEDLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMFNNRNLGGPYDR"
     gene            complement(39094..39810)
                     /locus_tag="TVR04_000604"
     CDS             complement(39094..39810)
                     /locus_tag="TVR04_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1269317.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKELIKTYLT"
     gene            complement(39982..40686)
                     /gene="nagB"
                     /locus_tag="TVR04_000605"
     CDS             complement(39982..40686)
                     /gene="nagB"
                     /locus_tag="TVR04_000605"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1269318.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAEGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMHDQLFNAKPFKESFLPNGLVDDL
                     EAEVKRYDQVIAGHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            40954..41982
                     /gene="queA"
                     /locus_tag="TVR04_000606"
     CDS             40954..41982
                     /gene="queA"
                     /locus_tag="TVR04_000606"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1269319.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIVAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            41992..43209
                     /locus_tag="TVR04_000607"
     CDS             41992..43209
                     /locus_tag="TVR04_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1269320.1"
                     /translation="MKYIHSRLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLDHLKPKQASYNFEQ
                     LYQSLQVIGSPAFHRMWERQPRAQHKLEAKRDLNLLLTYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLSSLVQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDVIETAMINPNSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKMAAKAFKKLLRHY
                     QQAHQSFPSTPPS"
     gene            complement(43866..45263)
                     /locus_tag="TVR04_000608"
     CDS             complement(43866..45263)
                     /locus_tag="TVR04_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269321.1"
                     /translation="MSNLISEVKSELAKNHQDALEIYILGEGSPKYSEVFPDRLGDYI
                     KDYKPVRLNGKAIHGRAFFMMKKEDQLVSTKEEYDRVIAERFSNLEKFDYPTIHYTFD
                     AELKDKYPYLNLILKANGLSLSDSISLDSILGINGVTIHTQHLRIDNQFAYRYTKDDY
                     KQDSHITFERFKRNDDKLKELIVTSGADREGLTDAQRVKAYVLYMANHVDYDWEAARY
                     NPDYLIFCQASDLFALTERNKAMCIGFSTAAARGLNLLGIPSYVTYGRNRNGAAHAAI
                     RVFYDKKWRTLDVTGVGRGKYTEEHYDNLNTHDYKIFDLTKETNVDLDRGYMEIYKDF
                     EDWILSHNTKELLFINQDANIRNKVAKDDFKYIQEAEKQSLIDKLKKFVFKVENISSY
                     FKKEHFKKLVIGLGEDAKNELAKLTLSPDLEEDDYKKSKTVLEWLNIYYSQCIREDGD
                     PDLIRKDGELKEMDS"
BASE COUNT        13208 a        10699 c         8566 g        12922 t
ORIGIN      
        1 tttttcgctt atcagcaaat aaacaagcct tgattacaac tttcctatta gttgaagcaa
       61 ggctgatcat tagacaaaaa agaaaagcta gaatggtcct ctagcttttc tttaggatta
      121 acaggcttct atactctctg tactgagtaa gtccaccgca gaggttataa gactatttct
      181 acaggtacaa atagccgatt agtgggttct gtcctgaaac cttttttaag tcgttcaaag
      241 taattgccgt agagcaggca aagcctctac ttatccagca cccttagaag ctatgccaga
      301 gctgggtatc aatcaagcca caaaaggcat caacaggaga cactccagtg aattcagatt
      361 caccagctaa ttttgcaacc aaagccttca tggtgttgtc cttgccatcg taagcgttga
      421 tataggtacc aacctgtggc atatcagcaa gggcaaaggc gtgctgaacg gaaacaacga
      481 ttgttgggac ctcatggacg tagaatggct gatccggggt gcccttagca gctggccaga
      541 taatacgctg aactgtacct ccagaattaa catctaccaa attaagaatc aaatcataat
      601 gctctgtaat gtttgaaatc ggctgctttt gtgcatagac attagcaata gctgctgcac
      661 gctcttcctc tggcagctgc atgatacgct cttcagttga ttcccaaaca gtcacctcat
      721 gcccacgcgc ctctagcaag tctttaacga tatctgaggc ccgttttttc tgtcctgcaa
      781 tcatagcccc aaagccaccc ttgtagccct caacattaac aatcagcaca cgcttgtagc
      841 gctctggagt taccgggaaa atccctgcct gcttgttttt gaccagagtt atcgccttat
      901 cggcaacctc atctgcaatt gcttgagact ctggtgtgtt aatcaaggcc atcgccttgt
      961 ccttaggcag catgatatct tctcggtgtc cttcaaagcg atgaagccca agctttgctt
     1021 tcaagccaag cgtacgacga agggcgtcat gaaggcgttc gtcacttaaa atccctgcct
     1081 catagccctc tttcatccat tgtaggtctt catctgggtc attaaagaat aaaaagagat
     1141 cgcagcctgc ctcaatcgct gttggtaaca ataagcgacg tggcattgag gctgtcatcg
     1201 caaccatatg cgaagcgtca gtcacaatag caccattata gccaagctca ccacgcagca
     1261 gctcatctaa gagggtttta ttaagtgagg ctggaagcat atcatctagc tcacgctcag
     1321 ggtgcatggc cttttcaaca tttggcaggt gaatatgtcc tgccataata ccaggtaagc
     1381 cagcctctgc aagctcgcca taaatacgtc caaagctaga tagccactcc tccttggtca
     1441 ttgggtttga ggcaaaggac aaatgatggt cacgctcatc aataccatca ccagggaagt
     1501 gcttggcaaa gggcatgata ccatattcca taatcccctt catatactct ttggaaagct
     1561 caatgatttg atcaacattt gccccccagt tgcgattagc aatgattgga ttacgccaat
     1621 tacgcgtcaa atcaacaatt ggcgcaaagg aggcattaca gccaacagct gacgcttcca
     1681 gtcctgcaat ccgtcccatt tcataagcgt atttaggatc gtttgtcgca gctaccttga
     1741 tttcatcacc aaccttagtg ccatcattga cagcaccatc accaccagcc tctgtattgg
     1801 cagcaatgag cattggaatc ttggatttgg tttgtaaaat ataattttga tcccaaattt
     1861 ctgaagccat gcctttattg tagcgaacag ctgcaatatg ataatcctca agcacctggg
     1921 ttaaataatc ctctgatcga ctggccccca tattaacaaa tagctgacct atcttctcct
     1981 ccaaggtcat tgctgcaatg gtatcctcca cccagcaaat agcttcttcg tctaggttat
     2041 atggtttttt tcttaaatct actaaatgtg tcattgtact tcctttcaac tagagccttc
     2101 tctgcttgct tttctgtttt aatgaatggc gctacagcag cctgctacca agccctaaca
     2161 ggctcagctc cacttgtctg ctgcaggatc tacctgccta cctatcaaga ttacgccaga
     2221 aggcttctgt aagactcttg acatcaagct ctgtcaagtc accggtcgta aaagcctcag
     2281 cagcatgtga caggtcctgc cacgagctag cctccttact aacgaggatt gggaaaaagg
     2341 tgatctggtt ttgctcagcc gccgctagat cacccggtga atctcctatc atcatcatgc
     2401 gctctctcac atatccttca tcaatgagct gtgctatgac agcctctttt ttgccacgat
     2461 cctgacaata caagccatca acatgtgtca tcaggccttg atcctgccat tccttttgaa
     2521 cagcctcttt attagctgag ctgacaacaa aaacctgacc aagctggtgc aaggccttga
     2581 gagcagctaa agctcctgga aatgccaatg cctctccttt gtaggcctca atctgacggt
     2641 tcacctcatt tgaccaatct aaggcccttt gcaaatcatc gctgggctgc ttaacaagct
     2701 cggcctcaag ggattgattg gataaagagg gtgtttcctg cacccatttt tttaaggcat
     2761 caatacctga aactccggca aactctaatc ccatcacaag cccaacaaag cgattaacac
     2821 cgcgtgtacg cgagtaaaga ttaatacgat cccattcttt taagaaggac acttgatctg
     2881 ctaccgcaaa ataatccgct gcaagcggac caaaaaagag ctgatgctta taagtcatgg
     2941 tgtccattgc gcagccatct gagtccacac aaaagacaaa ttgttcagtt ttagctgtca
     3001 tttcaacctc caaatcatct gatgaattaa ttctaacata gtaagaaaac gctgtcaata
     3061 acaaacctaa tatcagctgc gtttcttttt taaaagctat agttacttat tgattacctc
     3121 caaaggttag gctaataccc cttagcacta acccctaaaa tcatcatacc tttattaata
     3181 acatcttggc tacaaagcaa gctatcacaa tagaaaaacc acttgaggca ttgcagtttg
     3241 agttctcaag tggtttatgt tttagcttaa acgcctgaat aagctgcaaa gccgccatca
     3301 attgggagaa caactccgtt cacaaaggaa gcagattgct catcagccaa gaaaaagagg
     3361 cctccaatta attcttctgc ctcaccaaag cgtcccattg gtgtattctt cagaattttt
     3421 tcagcgcgag cagtcggctg tccgtcctct gtaaaaagga gactacggtt ttgattggtt
     3481 accaaaaagc caggggcaat agcgttacaa cgaataccaa ccttagagaa gtgaacagcc
     3541 agccactggg taaagttgga aatagctgcc ttagctccag aataggctgg aatctttgtt
     3601 aatggcgtaa aggcattcat tgaagaaatg ttaataatat ttgccccctt acgaccaacc
     3661 atatcctgag caaagacctg tgtcggcagc aaggttccta aatagtttaa attaaagaca
     3721 aagctgatac ctgcttcatc aaggtcaaag aaggtttttg tatcctctgg caggcttgtg
     3781 tcgtaaaact cattatcggt tgttgcctta gggctgtttc cgccagcgcc attcactaaa
     3841 atatctgctg gaccaaaatc tgctaaaact gcctgacgaa cggcctctag gttttcttta
     3901 gacaatacat ttgcctgata ggcccttgca atgcccccct ctgcctcaat atcatcaaca
     3961 aaggcctgtg ccgcctcttg gttaaggtcc aacagtgcca ccttagcccc tgcttttgca
     4021 aatgcctttg ccatactgcc acaaaggaca ccgccagctc ctgtgatcac aacaaccttg
     4081 tccttaaatt caataactcg actcatctca tgcccctttt ctatttatct ccaactgttt
     4141 ttacagtaat gccaaaatct ggtgtctttc cagctgcacg catattggcc tcataaagcc
     4201 cattaaaata ggtcgcacca agtgcccggt catacagccc atagccagga gttttgattt
     4261 gatctcccca gatacgacga ccatgatctg gacgaagcgg tccttgccag tcataatcaa
     4321 ccaataattt gataatagca ttcatatcaa tgtcaccagc ctgtgacaag tgagcggttt
     4381 cttggaagcc ccaatcacca gcagtgacat tacgcgtatg cataaagtta atacgctggc
     4441 gcttaagcgc gtactccgtc atagcgatca catcattttg aggatcagaa gcataggagc
     4501 ccacacacat ggtaatccca ttattagggg aatcataaag gtctaagaag cgctctacag
     4561 ccttttgacc tgttatgata cgtggtaagc caaaaatacc ataaggagga tcatcagggt
     4621 ggatagccat cttaacacca gctgcctctg ctgttggcat aatagcctta ataaaataat
     4681 ctaaattagc ccacaggtct tcttcagaaa tatgatgacg ataatgctca ataatagcct
     4741 tcatctcttc ctttgaataa gaagaatccc agcccggcag gttcaaatca tctgccacag
     4801 gatccacatc tgccaagtct gcctttaaaa aagcaagtga cgttgaccca tcaggcagcg
     4861 ggtaattgag gtctgagcgg gtccaatcaa acaccggcat aaaattatag caaaccacag
     4921 gaatacctgc cttaccaacg ttgatgatag aggtcttata gttttcaatc agctcatcac
     4981 gattgggctt gccttgcttg atgtcctcat gaaccggaat ggattcaatg actgaaatct
     5041 ctaagcctgt agcctcaact gttctcttca attcaaggat attttctagc ggccaagcct
     5101 gaccaaccgg tacatcatac acagctgtca caattccctg catgccagga atggccttga
     5161 tttcctctaa acttactgga tcatgctttc cataccagcg aaacgacatt ttcatagtat
     5221 catacctcga gttcttgtaa actccttttc ctttcgattc acacaattgt tattgttttt
     5281 gttttttgag ctaatgccct tacagctaaa aggcctgctg cttggtttag cctttgtgat
     5341 ctagccaacc aacaagacgc cgacagcagt cagcaggccg atattgtcct agcctctttt
     5401 aagaccagga tcttgaccat agagcaacat catatctcta tgcttcttat agctaacgac
     5461 caagacagcc tagctaaaat actggatagc gttattgtag gcaatgtctt tggccatgct
     5521 accgagtgcc tgataatcct ctggtacctc accttcttca atccattcac caaggtaggt
     5581 cgataaaata cgcctgaagt aatcatgacg ctgataggat aagaacgaac gcgaatccgt
     5641 cagcatgcca acaaaattag ctaacaagcc ttgctcagcc aaggcattca tctggctaat
     5701 cataccaagc ttggtatcag caaaccacca gcctgcacca aattgcagat agcccgcaat
     5761 accgttttca ttggcttgga aattagcaag cgtattggca acagtaatat tatagcttgg
     5821 atttaggtta taccagatca tttttggcag gctgtctctt tgtaccagat gatccaacag
     5881 acggttcata ttgatagcta gtgctgtttg atctcccagt gagtcaacac ccacatctgc
     5941 tcccagcttg ttgaaaatag ctgaatgatt attgcgaaga gcgccaaaat gtacctgagt
     6001 aacaaagcca tagtgcttat aaagcctaca aagctctgca aacaccgctg tctgccattg
     6061 cttgatctct aacggctgcg gctgatagcc ctctaaaacc cttgtcatga gatggtctaa
     6121 ttgctccggc tctgctgctt caaagacaat ctctgtaaag ctgatgtcac tggccttaca
     6181 accattttct gcaaaatagg caatacgctc ttccatagcc gctataaagc tcttaaaatc
     6241 tgtaatagtt cttccagtag cttgagcaag acgagccaca aaatctgcaa agcgctgatg
     6301 ctcaataaag gcttcatctg gtctaaaggt tggcgcgaca accgtctcaa aggtatcatc
     6361 agcagctaat ctcttatgcc aagctaggtc atcaagcggg tgatcggtcg tgccaataaa
     6421 ccgcacccga ctagctgcaa tcaactttct aggactaatc tggtgctcaa ccaagtaagc
     6481 attgatacga tgatagattt cctctgcatt atcctcagtc agcagctcac agacaccaaa
     6541 gacatttttc agctccattg ctgaccaatg gtaaacagga ttgccatagg agcgctgaag
     6601 cgtacgggca aaggccttga atttatccag cttagaggct gagcctgtga tttcttcttc
     6661 cgaaatgcca ttagcgcgca tcaaacgcca tttgtagtga tcaccaccaa gccaaaggtc
     6721 aacaatattg tcataaacct tatcctcaaa aatttccttt ggatctaagt gacaatggta
     6781 atcaaaaata ggctgatcct tgatttgttg atagaggcgc tttgctgcct cattttttag
     6841 cataaaattg tcgtcattaa aagccatctc gtcctcctct tatgaccaat tcccttaatc
     6901 aagggctgat acaaatgacg ctgcaatacg ggttacacta tcatagccct cagcctcaac
     6961 tcggctagct aaggctgaac caatcccaac agcaacagca cctgcatttt tccactcctt
     7021 gacattgtca atcgacacac cacctgatgg catcaaatca acctcaggaa taggaccatg
     7081 aatatcctta ataaagcctg gtcctacaac acctccagga aagaccttaa taatcggaca
     7141 agaggcattc attgctgtga caatttcagt agctgttgca cagcctggga aataaagatt
     7201 tgatgcctga ttggcaacct ctgctatttc actagaaaaa tgaggactaa ctaaaaagct
     7261 agcacccgct gcaatagcct ctcttgccag atcaggtgtc atcactgtcc cggctccaat
     7321 aatcacagtc tcatcatgct caaactcagt cgacaatgct ctaataacct ctgaagcatt
     7381 tggtgtcgaa taggtgattt caatattacg aataccgcct aaaatagcat gcttagcaat
     7441 ggcaatagcg tcttctactg tttttccacg aataacagca aaaaaataat tctcttttaa
     7501 tcggtttagc ataggctcct ccttttttat gaaaccgttg tcttagtctt attatacaaa
     7561 tcgtcagatg atttgtcaag aaaaaaacaa aaaaggactt ggttctagta tctctaaaac
     7621 caagccctct tattcgagcc aagaagcaaa tcactcaaaa ctcaatagac tgtttccggc
     7681 aagaaagctt aaacttatga tagaaaagcc gttcgcttaa ctgtcatgat gtgcaggagc
     7741 atagcgtcat atgccgcgat cggatctccc gctttaatcg cattcagaat atctctgtgg
     7801 gcttgtagag aatcttcttt catctgacga tttgtgtaat tggcattgat cagatgaatc
     7861 gactgattaa tcactggcaa caggctatcc atagcaatat tgccactgta ttttgccatc
     7921 aaggaatgga aattcacatc cagctgcaaa tgcttaggat caccagcagc tacggcctct
     7981 tcaatatcaa caacaagctt ctctaaggct tcaacctcct ttggcgttgc atgctgtgct
     8041 gtcaaagcgg caatcctagg ctcaagcaac agccgcaatt caaacaaatc agcggtcagc
     8101 ttggctgtat ccttgaccaa ggaaaagcct aaaggatcct cagaaacacc ttttttcgag
     8161 ctaatataag tacctgatcc ttgtctaacc tctaaaacat ttctagttgc taagcttcta
     8221 acagcttctc taatagtgct tcttccaacc tctaagtcct gcgctaactc atattcattg
     8281 gggagctttg ctccaacctc atatccccgt tctaaaatta gctttaacaa gcgctctgct
     8341 gttttttcga ctaaaggcct agccatacaa tcccttcttc ctacttattg ctagctacta
     8401 ttgtacacta tttcttttta taattgtagt ggggaatggt attccaacgt tctttaaaca
     8461 aaccaaccac atgcttaggc tggcgatttc tagaaaaaag ccccttgtga ttgccttgaa
     8521 tgcggaagat catcagatta gtttcaaaat cagcaaaatt ccatacctgc tctccgacga
     8581 gattaggaat ctcatcaaaa acgcggtgac tcatctcata gaagcggcac tgaaattcct
     8641 ctgtatatgg aatatcccac atcgaatgaa gaccaggaag cgtatctgca ccgtattcgg
     8701 tcattaggat tggtttttct gggaatttgc tctgccattc taatagctcc tgacgcagcc
     8761 cgacctctcc tttggtcaag tctccatgat caacatacca agcataataa cggtttaagg
     8821 agatcacatc aaccagatcc atcaccttat ctcgatcagg tgttgctaat agcagattaa
     8881 ccaatgttac tggacgctgc tgcggatcta gtgccttata aagagcaatc agcggctcaa
     8941 agtattcgtg tgctccctct tcatggctgg caggctcatt ggccacgacc cacatgacaa
     9001 cagaagggtg atttttgtca cgcttgacga gctcacgaat tgcttgctca tgcgcttcct
     9061 tagttttcat gacagaccaa gtgccattgt cctttggcga aagatccaag gaggctgtaa
     9121 agttttggaa gagccctact gccggaacct catcaataac caagattccc atacgatctg
     9181 ccagacgcat catctcctca gagtaagggt agtgtgaggt acgaaatgaa ttggcaccaa
     9241 gctccttgag cagattcata tccattaaat tagctgcttc attcaatcca cgaccgttga
     9301 taaaggtatc ctcatgctta ccaaagccct tgaaataaac aggcttgcca tttagtaaaa
     9361 attgtccttt ttcaactgca atacttctga taccaaatgg ctcatcataa ctatctacaa
     9421 cattgccatc tacgatgatc tcaacgtggg cagtgtatag ataagcatct aaaacttccc
     9481 ataaacgaac cttatcaagt cttgccttgc catcaatagc ctgcacaacg agcttgtgct
     9541 cttcatcaaa gatcgtcacc ttaacctcat caacagctgc tgaggtttca acagatacct
     9601 cgactaaggc tgatgtcata tcctcagaca agtcactcgt gatcgtgata tctgagatat
     9661 ggcattttgg ccgcaccata agcttcactg gacggtgaat accagcatag ttgaagaagt
     9721 caaaattctc cttgacaacc tttttgatac tgccatctcc ttggagctct tcgctataat
     9781 tgcccactgg aaggctggta taatctaaaa tattattggc acaaacagat accttaattt
     9841 gattatcctg ataaaggtcc tcaggcacca gcacttcaaa tggggtgaag cctcccttgt
     9901 gatgccctaa ggcttgccca ttaacataga ctgttgcatt gtgcgtgaca gagccaaagc
     9961 gaagcaccaa ttcctcatca gcagcaagat ctggcacatc aacaaagcgc tcataccaga
    10021 aatcaccaat ataattgcgc ttgtccttat ccacaaccac atcattaaag gaggtgggca
    10081 caaccattag ctcatcagag gctaaaagct cctgtgggtt atggtctcct agcttaaatt
    10141 gccagagccc ccctaaatca taaatctttc ttgtttttgt cagtattggg tataacatac
    10201 gatttctcct ttatcacatt atcgttgaat ctcatgcgat tccttggcca gtaaatgatc
    10261 aatgtcatct tgtgtcatga tattactatc accctcaatg gtatgcttaa acttaaagct
    10321 agccattgca atatctaaag tagcctgctc ttctttatga cttaataagc catggatcaa
    10381 ccctgctgta aaggcatcac ccgtccctac tcggtccaga acctgaatac cagatttttg
    10441 ggtttggtaa aggctgccat tttgatacag gtaggctttt aacaggtatt cattggtata
    10501 gcccatctct ctttgagtga aggcaaagca ttttacccca taggtatcag ctaacttagc
    10561 cagcacctcc tccaacaagg cctcgttatc atagggtcta ttcaagccta attgatcctt
    10621 taaatcaagc acaccacttc ctttaagcgt cagcggctca ataccgatac aaacatcagc
    10681 cagctgaaca agaggcgaca agagatctct agcctcctga aaggaggacc atagactggc
    10741 cctaaaattc aaatcaaagg aaatagtcac tccctctgct ctagcctttg tcatcaaata
    10801 ataggtcagc tcataaagat cactcgttag agcaggcgtt atcccagaca catgaaacca
    10861 atcagccccc tcaaaaacat gctccaaatc atagtcagca cgctttgact cccaaaaggc
    10921 agaatgacaa cgatcatagg taacccgact tgctcgcaaa gaaaagccct tttgataata
    10981 ataaatccct aagcgctgcc ccttttcaat aatatgctct tgattaattt gacgcgaaaa
    11041 gagaaaggtt tttgtcattt gtcccagatc attgtctgga atagctgaaa taagaaagac
    11101 ctgatgccct agctgagcaa ggcttgagat gacattaagc tcagaacctc caaattgaca
    11161 atctagactt gttgcctgct ttaatgtctg atattgagga ggtgacaatc gcaaaaggat
    11221 ttcacccaag gatacaactt ttttcacaac actcctcctt gtactatcaa gctactctgt
    11281 tatattctac aaaaaagtca gccactcctc aaagaaatag ctgacccagc acctaatcct
    11341 tatcaacagg atattttgtc acatcgacat agtccatgtc tgacagtggt acatttttag
    11401 cgatagcctg cacgcgttcc ttatcagagc ttgctttcat cacttgaatc ttctcttgaa
    11461 tacgcaccat ttcctctttg tcaagcttgt agaatgacat caaaatcaaa gccactagta
    11521 aggctacaaa tggaatacct acatggagcg caatcagggc catctttaaa cttggggtaa
    11581 gtggtgtctc aatcgttggg taggcctttg aaaaaccaat accagccagc actgcaccaa
    11641 taaccattgg cgcaaatgat gatgcaatag agtcagtcaa ggaaaagatt gtaccaatca
    11701 ttcctgatac ataacgacct gattctgatg tttcgtagtc tgaaatatca gcacccattg
    11761 ttagcaccaa gctagcaggc gcttgtgagg catagcgagc aataataagt gtcacagtaa
    11821 ataaaacagt gtaaaggtta atatggctta agctgagatc tcccttatta cccataaaga
    11881 gcacaatacc aaaggctaac aagccaacca agccaatctg aagagctctg atgtatgaga
    11941 aacgcaagcc tctcttacga gcaatgcctg aaaaagcaat attaatcaaa attcctggaa
    12001 caataaatag caatgagaat tgaccagaca aggcatagtt accaaataaa acaccaaaca
    12061 ggataaccat gacaaccgaa tcaccaaaga attgaacagc aaacttaacc agcgctgctg
    12121 caattgataa aacctgcaat ggctgattgc ccttgataac cttcaaatag tccttcagag
    12181 ctgtcttttg cgtattttca ccaagaccaa agaattcctt tctgtccttg ctccaaatac
    12241 caagcactgc caataggccc aaaatagctg agataacaat agtgccataa atcaaaacat
    12301 ggaagaaggc tggtgtgaag ttgccaaatg ttggaaccaa gaagctggat acaacaaact
    12361 gtccgcctgt catcaacagg gttgtcataa tcgcatcaac aatattaaaa ataggacgtt
    12421 gcttcggatc atttgtgagg gctgtctgac cagccttagt aatggtttgc tgcatagagt
    12481 agccgatttt atgaataatc aaaaccatga taaaaagtgg gaaacgaatt ccttcatcaa
    12541 caccacttag accaagcagc aggataagtg atagggctgt gataatattt cctatgatta
    12601 ggatcggacg atacttacca aatttagttt ctgttttatc aatcaagata ccaatcgcag
    12661 gatcaataaa gccatcaaag atacgaatat aacccatgat ctggctgaca aaaatagccg
    12721 ccaagcctag aacacctgtt gaaaaatagg tcacaaacat aaatgtgaat aggtagatat
    12781 tggttgaagc attgttcaaa gcaaataaaa caagctgcca aaccttagcg cggttatagg
    12841 taacctcttc aaccctttgg tcaattgttt tctccatcag agaaatcccc cttttatcat
    12901 tcgcttatag tgtaagcgtt ttatttctac atgcctatct tactattcat ctgacgattt
    12961 gtcaacacaa tttaaacttt tttcgcctga ttttaaaaaa taaagcttat ttaggattgt
    13021 tatcattaaa ttcatctgat aatttctgat atctttaaaa atagtcatca gacaattaat
    13081 cattgacacc aaaaaaactg agccctgcac aagacagagc tcaagccttt taccaacact
    13141 tatccaaccc ctttgaggtc agtatcgtca ccccaccaac aggataggca ggggcttctt
    13201 caaaaccaaa agcccctaaa accactctca taccaagcag tcttaggagc tctaagcatt
    13261 catgtcaggt gataatcatt aggctatgaa agccttcagt tcttaatcct caataagctg
    13321 aatatcagcc cctaaggctg ttagcttatc aataatgtta gcgtagccac gtaaaataaa
    13381 ctcaatattg ctaatctcgg ttttaccctg agccatcagg cctgcaatca ccaaagcagc
    13441 accagcccgc aaatcagttg ccttaacctg tgccccactg aggcgattag agccatgata
    13501 aacaatttgg ctgccaagaa tggcaatatc tgctcccata cgagcaagct ctggcacatg
    13561 gttgacacgc ttttcatata tcgtatcaat gatactacca cgaccctcag cccttaaaag
    13621 cagaggggtc aaaggctgct gtaggtcagt agcaaagcct ggatagggag aggttttaat
    13681 agtgactgct ttcaaagctt cctgcttttc cacaaaaata gaatcctctt caaccgtcat
    13741 tctcacaccc atttcctcca gcttagcaat aaagctctct aagtgctcgt aaaggacatt
    13801 ggtaatcctt accccactac caatagcggc cgctaaggca atataggtac cggcctcaat
    13861 acgatctggg atcacctgat gcctggtacc atgaagcctt tcaactccct caatcgtaat
    13921 cacatcagta cctgcaccac gaatatgcgc tcccatgtta tttaacagtg ttgcaacgtc
    13981 aataatctca ggctctctag ctgcattttc aataatggtc ttgccctttg cctttgtcgc
    14041 agcaatcatg gtattaatgg tagcacctac gctgacagta tccatgtaaa tatgagcacc
    14101 atgaagctgc tgatcctctg tcatcaagcg catgctttct ccctcgtaag atatctgagc
    14161 tcccatggct tcaaaagcct tcaaatggag atcaataggc ctaggaccca agtcacagcc
    14221 acccggcaag cccacaaccg cctgcccaaa gcgccccaat agacttccgt aaaaataata
    14281 agaggctctt aggctgttaa ttttaccata aggcatagga atatcttgaa cccctctggg
    14341 gtcaatctcc aaggtatccc cctgataggt caccatagct cccatgagct tcatgatttc
    14401 aataagactg tcaacatcac taatagctgg taccccatct aaagtgacaa catcgtctgc
    14461 caaaataatc gcaggaatga gagctacaac gctattttta gcgcctgaaa ctgccacctc
    14521 tccggataag gcttttccac cattaataat aatttttcgc atactttcaa aactttctga
    14581 tactagaatt caaccttttt attttatcac aaatagcggt ctattacaat cacctcatct
    14641 accagccgct gcaacaggct ttacaacctg cctcttgatc acttttcata acaggttttt
    14701 gagaagccag actcttatct ggatctttct tctgctgcgc aggccttttt gtctttcata
    14761 gccaccaagc ctgacaagtt ttgctggact aaaaaaactc ccaactagca gcacagccac
    14821 tagctcagga gctattgtat ttttaactga tcatcaactg actgacgcgc aagctgctta
    14881 agcaccctct gacagtgctg ctaccgcctc tgtcaatgga gataccttgt ctaagtgttc
    14941 ccaaggcagg tcaatgtctg ttcgacccat atgcccatag gctgctgttt gcttatagat
    15001 cggacgcttg agatcaagca tcttaatgat ccctgccggg cgcaggtcaa agacctgacg
    15061 aacagccgct tccaaaatac tttctgacac tgttgatgtc ccaaaggtat ccacacgaac
    15121 tgaaactggc tgtgcaaccc cgatagcata agctaattgg acctctgctt tgcttgcaag
    15181 ccctgctgcc acaaggtttt tggcaatata acgagctgca taagaggctg agcggtcaac
    15241 cttagttgcg tctttaccag agaaggcacc accaccatga cgcgcatagc caccataggt
    15301 gtcaacaatg atcttacgac cagtcaagcc agaatctccc tgaggaccac caataacaaa
    15361 acgcccagtc ggattgataa ggaaccttgt cttttcatct agatagtggg ctggaataac
    15421 agccttaatc acctgctcaa tcatatcttg acgaatctgg tcattgctta cttctggatc
    15481 atgctgggtt gatataacaa ctgtatcaac acgcacaggc ttatcatgtt catcatattc
    15541 gaccgtaacc tgtgatttag cgtctggacg caaatagctg atctcacctg attttcgcag
    15601 tgtcgccaaa cggcgtacaa gctggtgaga taaggaaatc ggcagtggca ttagttctgg
    15661 tgtctcatca attgcaaagc caaacattag cccctgatcc ccagcaccaa tcgcattgaa
    15721 atcatcgctt tgtccttcac gtgcttcaag tgcttcatta acgccttgag caatatctgg
    15781 tgactgctca accagagatg gatgaacacc cactgattct gctgaaaagc catattctgc
    15841 ctcagtatag ccaatctcag cgatggtatc acgaaccaca cgattaatat ccacataggc
    15901 agttgttgaa atttctccaa aaacgtggac cgagcctgtg taaacgcagg tctctgcagc
    15961 aacgtgtgcc tctggatcct tggctaaaat agcatctaaa atagcatctg aaatttggtc
    16021 tgcaatctta tctggatgcc cttcagatac tgattcagac gtgaaaagtt tacgttctga
    16081 cataaaaatg tcccccctta aaaagaatga tacccaccag cacacatgcc agataggatt
    16141 ttcctagcct cactcatcaa gccagccgcc aatacaaaag aactgtatcc aagctagcct
    16201 atgactaacg cttagcgagt tacaaagtac cggcttttag actgctatcc tcagataaca
    16261 aagccgtctt atcgggactt aataacttat ttattatacc acttttagcg ggatttgtaa
    16321 gagctccatc agcttttttc tcaaaataag aaaaggaata ccgctacagg cgtattcctc
    16381 ctcttaatgt cgtgataatc agcgcaagct atcgattaac catggtggtg ctcatcgtga
    16441 tcatgatgct catggtcatg cttatctgct gcctcttgat cagtatcagc cggcttatgc
    16501 tcgtcttcaa cagcttctgc tggtgtggca ttatttagac taccaccctc tgctaccttg
    16561 aagttcttga taattccttg tgggaattgt ccttgttcag cagctagctc ctcagctggg
    16621 aagtgattac cgtcagcctg aatgtatttc agcgttttat taggctcctt caaggctaag
    16681 gtattgatct tgttgcggtt aacattgatt gactctaggg ctaaatagct attcacaccc
    16741 tcaaaattag tcagctgatt ctcctcaaga ttaagtgatt gcaaggagct ttgtgtacct
    16801 ggtaaggcca agctattaat catgttctgg ttagctgata gctgaaccag gctcttattg
    16861 tgctcaagac ctgtcaagct gttaagcttg ttttggtcaa ccactagctg ctctaatgcc
    16921 ggtagatcct tgacaaagct aaggctttgt aaattaacct ccttggcagt gatttccttg
    16981 agagcagagg attttaaggt tgacaaatca aggtcagggt tgtttgacac aaagagtttg
    17041 gtcaattgtc ccttgtttga caaggcactc aagtccttaa tctgattgtg ctccaggctg
    17101 acagcgacta gcttttgagc atttgccaga gcagaaaggt ctgtaatctt gttaaagtca
    17161 aggttaacgg actctaggtt tggcaattcc ttcaaaatag aaatatctgt gatatcattt
    17221 cctgctgccg aaattacctt gtaatgcgga aaggctttaa ggaagctcaa atcagaaaca
    17281 ccattttgag aaatatcaat tccttcaagt gttggcaggt tcttcaagaa atcataattt
    17341 ttaatgccgg tctgtgtcat ccacaattgt ttgaggttct tgaactggta gactggtgta
    17401 atatcagtaa ttggtgtaaa gccaatacct aaaatctgta tattaggcat caggtttaaa
    17461 cctgcccgct taagaggatc cttgatctca ccaatattga gatactcaac agtcgccaac
    17521 catgccttca ttttttctag gtctcgttct cttgatggaa actcagttgg cgcactcgcg
    17581 tgaataattg atgaaatgac ctcttcatca aagccaagct ttctcaaggt tgccatacca
    17641 atcctatcct tagcgtgtgg atctaccgca tgaggatcaa acggctttga taaatcaatg
    17701 tcatcaatat aggtcgcatg acggtggtca ccatgtggat agtcaagaat gacaccttct
    17761 tctgtatgct ccacacgaat gctgtcctca ggaatattta atgacttagc caaatgtgct
    17821 tttttcaaag cgattgtttt ctcaagatca ctttcaggct tagccggtgc ctcttccttt
    17881 ggtgtttcaa ttaaatgctt ccacttactg tgacgcaggc tttcataagt gactaaatga
    17941 ttgtgcccat tgtggtcaac aatcaagcca taagatgttc gaccgacaat ccctgtacca
    18001 tcaaataaga agccgtcgct agttgggtaa tcaacacctg caaattttcc agctggtgat
    18061 gatggatttg acagcggcac atgattaggc actggatagg ctacctgacc acctagtgag
    18121 ctttttagaa tatagtgata atgatcccca tgacggacaa tatagcctaa ggcgtcctca
    18181 gctacaatat cagctgggtt aaacacatag tgatggtgcg ggtcattagc actcgtatgg
    18241 tgatgacctg atgctgcctt ggtctgctca ggcttgttta ggtcagcgtc ctttggaatc
    18301 aggtactcaa acttgctgcc cttgaggtct gcataaaaga taaagtgcga atgcccatca
    18361 tgctcaacaa caataccatt ttctgttcta gataaaattt ttgagtcctt cgtcaagata
    18421 aagccgtcat ctgttgggaa gtcaatcccc gctactccct tacggtcttt tcttgttttc
    18481 ttaacctttt tagactgctt cttcttggtg gcttttttag ctgtctgttt tgtcttaggc
    18541 tgatttgttt gctgctttgt cgactgacaa gctgtcaggg tcaagtgaca ggccataaac
    18601 aggctagcca ttagcattaa ttttttactt ttcatctttc ctccataaat taactagtta
    18661 aataagatat taactagtta attataccaa aaagacaaat aatttcaact gttttcttat
    18721 tttttagtca ttctcattca acaatcataa tagcttggcc aggttggcag aaaaatgggc
    18781 tcatcctatt ctcatcaaat aaacagatag ccttaatgat ggctgagatg acagcataca
    18841 aaatccttaa agccacttgt aagaaaaaga aagacgcaat gccataccac caccatctta
    18901 ctcatcaaag ccctgcggct ttcagacaaa atcttcgtaa catcagaaag gctgatggag
    18961 cagctcagac aaaaagagca ggctccttaa tgccaaggat caaagatcag cacaagaata
    19021 acagcaggct tcgttaatgg ttgtaattcc tcaaaaagga tcattttctg tataaaggaa
    19081 agcgttttcg ctagctattc catcatttca cgtcacctgt gtttattttc tcttgaaatc
    19141 cagtcatttt atactatact agaattatga agacatctga aaaaatttac caattactag
    19201 cttgtagcga tgactatgtc agtggagaat acttggcaga gcagctcaag ctttctagaa
    19261 cctctgtctg gaaatccatc aaaagccttg agagtcaagg ccttcatatt gaatccctca
    19321 agcataaggg ctatcgcctt attcaaggag atctactgct gccagagctc atcagccaag
    19381 agctaggcat tcctctttcc tacaatgaga aaagccagtc aacacagcta gatgccaagc
    19441 aaggaataga gttgaagcat accgctccta ggctctatct cgccccaagt cagtatgcag
    19501 ctaagggacg gcttaatcgc caattctttg cgtcacctca tggcggcatt tacatgtcct
    19561 tgcatctcaa gccaaatgtt ccttacgcag acatgcctcc ttacaccatg atggtggcct
    19621 ctagtattgt taaggctatt tcaagattga ccggtattga cacccaaatc aaatgggtca
    19681 atgatattta ccttggccat aaaaaaatcg ccggtatcct gactgaggct attacctctg
    19741 tggaaacagg cgtcattact gatgtgatta ttggcgtagg gcttaacttt tttgtgaccg
    19801 aatttcctga aaacctcaaa gaacgagcag gctctctttt tagcagcaag cctagtatta
    19861 ctcgaaatgc cctaatcatt gacatttgga agctctttac cacaatacca atcaaggacc
    19921 atattaaggt ctacaaagaa agctcacttg tccttcaaaa acaagtgagc ttccaagaaa
    19981 atgatcgtca aaaaacagca actgccattg acctgactga tgaaggacac ctcatcgttc
    20041 aattagacaa tggtcagcta caggtcttaa ggagcggcga aattagtctt tcttcctggg
    20101 gggattaaca gcattaatga tgtttttggt aaattggtca atagcataag cacgccttaa
    20161 atctctaaag agcaaaagac cccaaaacag agcaaaaata taatcgcctg aaaataataa
    20221 atcgctaaaa aaataagctt caaaggcaca aacgaatgcc ataaacataa attgtcgaat
    20281 agtcatgcta ctattatacc aagaaaacta aatttccact aacgattttc acgcagcttg
    20341 aagaaaaagg cagctagccc acttcaagct tttttgctgc tctttgatag cctgtaacag
    20401 cagctaaaga aagggctcag tctaaaaaca aagccaaaag ccagcttgat tgctagattt
    20461 ttagccaatt gtctcaaatc agtgaagtac taagtctgac aaaaactccg ttggctggat
    20521 cataatgata tctaagctct aaacagcaaa aaagaggacc acaccggtcc tctctagctt
    20581 ggcttgtcag ctatctatta gtgctgacaa tgagccctgt catctcctta ttctagacaa
    20641 ttgatacact actaatcatc agctagcgct aatcctctat gagatgaatc ttatcagtta
    20701 aaaagtcaaa cccctcaggc atgtcaaagg tcgcttgctc aggctctttg gctgtctctt
    20761 ttttggtttt gatggtcatg gcaaactccg agcgaatatg gtggaagtct gcctttggta
    20821 ctgccaagat atgaggagaa aaccctgctg ccttactcat gatattccca aacatatcat
    20881 tcaaatcctg acgcttcatg gcctgctcag cgttaaaggc ggcctcaaag gccaaaatag
    20941 cattttcact attggctaaa acaggctccg agcctaataa caaagctcga tcctgtgcag
    21001 aaatactatc taaaatctca ttccaagcac tttttagcgc ttctaaatat tgtcgtgact
    21061 gctggctatc ttgaacagtt tcctccatga ttttcaatat cttttcccga tcaaccttgt
    21121 aggtaaaggc ctttggcttg atagaatgag ctggcgtagc ctgtgcagtt agaccttttt
    21181 gagcctgtag ctgtgatatc gtctccctca actggctaat ttcatgcttt aagccatcaa
    21241 catcagctag caggctagat ggtattgcag tgtctgttac ctgtccctgc tctgccagct
    21301 gaatggtcat catttcagcg tatattctag ggtgggttcc ttttttgatc tcaggcaggt
    21361 gcttggttac ggtagcaatc atggtaaaaa gctgatcaaa agacactgca agattgtcat
    21421 caaaaagagg ggactgcctg tgatgatcac cacctgattt cacaatgagc aggtctctaa
    21481 aataggttaa caagtccgtt gcaaaacggc tcatgctctt gccactatca taaatcgttt
    21541 ctagattagc taaggcctga cttgtttttt gcctgatgag atgctgaacg tagtcgtcca
    21601 aggctgaaat ggaaatagag cctgtgattt cttctgcaat agcaagcgtc acttgattgt
    21661 caaaggatag gctcaaggcc tgatctaaaa tggatagggc atcgcgcatg ccaccttcag
    21721 cccgtcttgc tattaaatga agcgcctctg tttcataagc tatgccctct ttgtccagta
    21781 tcgctgccaa atgctcacaa atagccgcct gcttaatggc tttaaactca aatcgctgta
    21841 ccctagataa aatagtagct ggaatcttgt gtaattctgt tgtggctaag ataaaaacca
    21901 cattgtcact cggctcttct agggtcttta ggagcgcatt gaaggctcct gttgacagca
    21961 tatggacctc atcaataata taaaccttgt aggttgcccg actcggggca taggttgact
    22021 tatctcgaat atcgcgaatt tcatcaacac cattattaga ggcggcatca atttcaatca
    22081 cgtcctccag actgccagtt gtaatatctc gacaaatatc acaatgattg cagggctctc
    22141 ctttaacctg attagggcag ttcattgcct tggcaaaaat tttggctgcg ctggttttac
    22201 cagttcctct tggacctgaa aagaggtagg cgtgacttat ctttcctgac tcaacagcct
    22261 gctttaaggt ggtcgaaata actgactgcc caaccatttc agcaaaggtc tggctacgat
    22321 acttccggta aagggcttga tacattaatc ctcaactcca aacatgtcaa aacgaaaagc
    22381 tgttttttct agtaatagag ctacaaattg ctctaaatag tcttgatcta tctgatcata
    22441 atcagcaaca agactggaat ccaaatccag aaccccaaca agcctgccag ccttaagcat
    22501 tggcacaaca atctcactca tggctgctga atcacaggaa atgtaattag catgctttct
    22561 gacatcatca acgatgatgg tttgaccaga ttgtgctgct tctccacaca ctcctttgcc
    22621 aagcttgata tgcacacagg aaaccttgcc ctgaaaggga ccaaggatca attcttgacc
    22681 atcaaaaagg taaaagcccg caaaaacaga atgaggcaag gtcattttta agagagcact
    22741 ggcattagag agattggcca aggcattgct ttcattagaa aataaggctt tagcttgagc
    22801 caataatagc tgataatgtt caatttttgt cgtcttattc atggttctta ttataacata
    22861 tctgctacta atcgttaaac gatttccaca ggaaaagaat tttaatcagc ctctctagaa
    22921 aagaaaggga ttttatgata aaatagtgag taatattaaa aagattagga gagtcagatg
    22981 ccattgttga gatacaaaaa gattatcgct acgaccttat ttatgttatt agtgtttaat
    23041 ggcattgagt atgaattttt aaaccttgtc agtcccaaac aaacctttta ccaatccgct
    23101 gccttaatcc tctcaaccag cctactaggg atctatttga ttcccttttc actggctatt
    23161 gcttatctca agcgcatcta ccagataagg atctcaaccc tgctattagc tgggctaggc
    23221 ggtctttata ttagtggctt tttagcctcc tttggcaatc aggttttaga gcagttttgg
    23281 attagcctga taaagcccaa tattgcctta gaggagtgga cgggagcttt gacagggcct
    23341 tttgtggaag agcctattaa ggcctttgca gcaatgcttg tcatttattt gttgcctact
    23401 atcaatctta agcaaaaatt agtcatcagt ctcatttctg gcatgggatt ccagctgact
    23461 gaggacatta gctatattgc aaatgcggct gatcggtcca taaatgacat tttgcccaca
    23521 acgcttgcca ggattagcag ctcaccaaac tctcattggg tctatactgg tatttttaca
    23581 atgggagtat accttttaat taaaaaatct caattatttc caaggtctct acagattttc
    23641 tggatggtaa gtcctctagc cctacatttt atatggaact ctcctatctc agatttagct
    23701 ggtgttgctg ttattcatgg aacaataaca acacttatct ttatcagtct attcaaaaaa
    23761 atccatgccc tagacgacag catcgcttac tagcgtcata ggacacgagc aaccaagccc
    23821 agccgcattt gggcatgtga tggctcatat gcatatatag ctactcacct cgcttaagct
    23881 ataggcagct aaatacctat cacaatagca gaaaaaatga ctaccagtct taaaagggct
    23941 agtagtcatt ttaagctaaa aacaagcact tcttacagga tataccactg atacagataa
    24001 tagcaaagca ctagggtgat cagtatcccc atataccatg aaaggacaaa ataccatttc
    24061 ttcgttttat ggttaaaata atgcccagct agataggctc caatcccacc acataagagt
    24121 gacaacgtta atagcatttt ctcagaaagt cgccattgac ctttttgggc tctgtgttta
    24181 tcactgccat aggccgcaaa aaccacagca ttccaaccaa aaagcaagat taggcttggt
    24241 agcatttgtc tgtctccaat cacagcacta cagctcacct aagatgctgg caatctttgt
    24301 gttgatgaga tcaatagcaa ccacattgct aaccccttct ggaataacaa tatcagcata
    24361 gcgcttactt ggctcaataa attgatgata catcggcttg acaacgcttg tgtactgctc
    24421 aataatgctc tcaaggcttc tgccacgctc aaccatatca cgctgaatac gacggataat
    24481 ccgaatatcg tcatctgtat caacaaaaag cttgatatcc attagctcac gcaaacgctc
    24541 gtcctctaat accagaatcc cctcaacaat aatgacgtcc tgaggctctt ggcgaaaagt
    24601 tctgttgctg cgagtatgct ccttgtaatc atagattgga atatcaacag gtcggccagc
    24661 caagagctcc tttagctgct gaatcataaa atccgtatca aaggctaacg gatgatcata
    24721 attagtctta accctttcct caaagctgat atgtgattga tccttgtaat acgaatcatg
    24781 ctgaatcatc gcaattctcg catttggaaa gctatttaaa atggcacgag acacgctggt
    24841 cttaccacca ccagaaccac cagtcacacc aataataatg ggttttttaa gcattgtaaa
    24901 ctccaaatct aaaagtcttt cggtctattt taccaaattt gccactataa tgctataatg
    24961 aagagaaaaa caaaataaaa ggatagacat atgataacca accttcccac tcaatggcag
    25021 gaaaagctgg caaagcttgg ctttactaat ctcaccccaa tccaagagca ggtctttcag
    25081 cccattgttg atggcaaaag cctattaggc attagcccca ccggaacagg caaaactctg
    25141 gcctatttat ggccaagcct tctcaggcta agccctaaaa aagcccagca gttgctgatt
    25201 ttagcaccta atactgagct agctggacag ctttttgagg ttaccaagga atgggcagag
    25261 cccttaggat taactgcgca gctctttatt tccggaagca gccaaaaacg ccagatcgaa
    25321 cgcctcaaaa aaggcccaga aatcattatc ggaacaccgg gacgcatttt tgaattagta
    25381 aggcttaaaa aaatcaaaat gatggccatc aataccatca ttttagatga atacgacgac
    25441 ctactgagtg actcccaata ccagtttgtc caaaaactct cccatcacgc gcctcgtgac
    25501 catcaaatga tctacatgag tgctactaac aagatagagc aagccagtct agcggatcat
    25561 accttggtca ttgatctgtc taagcaagca ttgccttgca ttgagcactg ctacatgctg
    25621 gttaacaaaa ggcatcggac cgatatccta cgtaagctag caaatattcc tgactttcgt
    25681 ggtctggtct tttttaacag cctgtcagac ctaggtgcta ctgaagaacg cctgcaatat
    25741 agtggagctt ctgttgcttc tctagccagt gatgtgaatg tcaagcagcg aaaggccatt
    25801 ttagaagcct ttaaagagca gagcatttca ctgctgcttg cgacggacat agtcgctcgt
    25861 gggattgata ttgaccagct agaatacgtc attaacgctg aggttccccg taataaagag
    25921 caatatactc atcgagctgg tcgaaccggt cgtatgggac gatccgggat tgtcataact
    25981 cttgtcagtc accctgaaga catcaagcgc ttaaaaaaat ttgccaaggt caccgagatt
    26041 tacttgaagc atcagcaatt acatcaaaaa tagcagcgat cagcttaaaa actaacctca
    26101 atgccttatt cctaaggaat tgagtgaata ctgctggttt cgttgccaaa agtccaatct
    26161 taaaaacgaa cgtaaggttt tgactctatg tcagaaatac cttacgttcg ttttctacta
    26221 tattgacgtc actggctttt ttaatagcag acactagcca tgcttaacca gactaaacaa
    26281 tctcttgaaa tgagtccacc acttagtcac gcgccagagt cttatttgct ttttcaaact
    26341 gactatcgac tgccatatag ctcagataag gtcacacatt tgtagccttc cgcttttagg
    26401 tattccataa tacttggcag ggcatctaca ctggtctggt gaatatcgtg cattagaaca
    26461 acccctccag gctgcaattg ctgcttgaca tttgccatga tagcagcagt attgcgattt
    26521 tcccaatctc tggtatcaac tgtccaaagc atttccttaa gacccgatgc ccttctaaca
    26581 atatcattag tagctccata aggaggacga agatagactg ggcgttttcc acaagccttt
    26641 tcgatggctt gattggtcgt attgatctgt gtttggatct gatcaacggt tagggtcgtc
    26701 aaatcagggt gatcccaaga atgattctca acatcatgac cagcagcact aaccttctta
    26761 accaaagcct catggccaac aaccttagac cccatcataa aaaaggtccc cttggcctga
    26821 tatttggcca aaatatctaa aacctgcggt gtggtcacag ggtctggacc atcatcaaag
    26881 gtcagagcga ccagcttttg tccctctttt tctgcctctt ttgccttctt ttcctctaaa
    26941 tagtcatcat aagcagtctt atctgaaccc tctagaaaat ctggattaat aacatcaaac
    27001 aggcttgcaa gaggtattga catatgacca agtaaaataa gattacccga atcaatggca
    27061 aaaccatcgc ttaatacctg atttttttct atcatcgtat cagtgctcag cttgatctct
    27121 ttgcctggat aaagcttgcc aacctcttcc tcgatgcgat ctaagcgacc agcaactagc
    27181 tcctctagct taaaggggct ataatcctct ttcacatggt aatgactaac agccttttct
    27241 gtagtctttt ttagaccaaa taactgaggc ttgtagaccg tcttgtagat aaccaattga
    27301 ttgacctgct tgatatgtga agcctcaagc ttaggcttta ccatgataac agccttgtca
    27361 gtctgcttgc cttgatacag agacataggc agatttgaca cataaaaatc gtcagccttc
    27421 tcaatcggag acaggtaata ccaatcctgc ttccctttct tgaggtgctt gacctttttg
    27481 atctttggac tatccttaga agcagtctgt tcgagcttaa tgactctctg agtatcctgc
    27541 cctattttcc aagatctaat gaaggtaaac gcaacaccga ccaacaataa acttaataaa
    27601 ataatgagaa tataatttag ctttttcaat ctcgtcctcc aattacccta caattttaac
    27661 acaagatagt tggaaaataa ataaaaaaag ttaggtttcc ttaacttttt tcagtccaaa
    27721 ataagggcaa aaaaatgttt tacggtgcag gatttgcctg agctattttc cctttatcac
    27781 agccatttgt cactggataa ggggctagac attataccta aagcttctct ttattgctat
    27841 cattattctg acattcttag gcatgctatt tcccttgata ggacttgatt gctgtttctt
    27901 tagcttgtaa ggatctctta aaaatgagac tatttttaag cctataattt atatattcga
    27961 aaaattttgg caaaaatgag aaaaaatatt gatttattta gctttagtga taaaatgagg
    28021 gtgaaaaatt aaataaagga ggacattgat atgtctcaga agttgggaaa acaacttatt
    28081 cgcactgttg ttactgcctt agccgccata gcatttggaa tatttcctgc aagcgagacg
    28141 actaatcata tcacctatgc agaggttaac tccttaaccc cttcggtaga atggtcttta
    28201 gagcagtatc ctaattacta tagtatagaa ggaaagtcta acatcaacac caaggatttt
    28261 cctaagctat acaccactac cgaaaaggtt tacaaaaaaa gtggtcgaag cactaagcgc
    28321 gttactgttt ctgatctgca atacgctgca cttgatggct atggtcgttc aggagctgcc
    28381 tatggcatta tcacaaagga tatgatcgcg atgtcagccg gataccgcga aaaatgggaa
    28441 agcaaccctg agccaagcgg ctggtataca tatcatttca aagaaactgg caagctagct
    28501 actgaggcca actaccttca cagcaaaagc aaggtcaaac gaacctcaaa caatagctat
    28561 gaaagcatcg tccttagcaa cggtaagatt cgtaacggct atctttttga tcgtagtcat
    28621 ttaattgctg acagcttagg tggtcgtcct tttagaaata atctcatcac aggtacacgt
    28681 actcaaaacg ttggcaacaa cgaccgcaag gggggtatgc agtacattga aaacaaagtc
    28741 ctaaactata tcaatcataa ccctcaggtt cacgtttatt acaaagccgt accaatctat
    28801 tcaggctctg aattgctccc tagggccgtt gtggtttcag cgctctcctc tgatggtaaa
    28861 attgatgaaa ccgtaagagt ctttaacact gtcaatggct ttaccatcaa ttaccaatat
    28921 ggcggcatca gccatgataa gggcatggag gcttctagtg agtcagaagc tgaggatatt
    28981 acagacgaaa gcactccagc agctgaacca gctgatgagg aggctatgga gacagaggct
    29041 gctgctaacg acacaatagt ctatgttaca agtaatggcc aatcaaaggt atactggtat
    29101 aataaggacc atctgccaga gaaggtcaat ctcaataagg ttgtagaaat gaccgagcag
    29161 gaagccctaa atcgaggaaa gcaccattcc tccttagaaa aaataaatca atagtctcat
    29221 aacgactaac acaagagctg gttgaagcaa ccagcttttt ttgtgtgatg aaggattaga
    29281 cagctccttt gctaaaagat aaagaggctg ataaagcact caacctctta tcgcttttat
    29341 aaatgctctg gtactgcggc taacagctct gatagcttgc ttgcatcact accacctgcc
    29401 atcgccatat ctggcttacc gccaccacga cccgacacga ttggcgctaa ggccttaatc
    29461 agattgccag cgtgagctct tttgtcctta cttgcaacaa gaacattgac cttctcacca
    29521 atgcttgcag ccagcacaag gacatctgaa taatcccttt gcttccaatt atcagcaaag
    29581 gtacgcaagg ctcctgcatc tgatacggat acctcactag caatgtaacg tagatcgttt
    29641 gcttcctgga cctttttaaa gacatcacca gcctgagctg ctgctgcttt ttcttttagc
    29701 tctgctattt ctttttgcaa atcgcggatc tgctcgctaa ggctcacaac cttacttgga
    29761 agctgttcta tttgcggcac cttaagcgta tgtgcaattt cttttagggt gtcttcttgc
    29821 ttgcggaagc tttcaaaggc ctgctgacct gtcactgcta tgatacgacg tgttcctgag
    29881 ccgattccct cttccttgat aatcttgaat agaccaattt ctgatgagtt ggataagtga
    29941 gtcccgccac aaagctcaac agaataatcg ccaatctgaa caacacgaac agttttgcca
    30001 tatttttcac caaagagggc catagctccc atagcctttg ctgtttcaat atcagtttct
    30061 gtggttgtaa tggctaatgc cttccagatt tgctcattga cctcttcttc aatgcgacga
    30121 agttcctggg ctgtcacggc ttcaaagtgt gtaaagtcaa agcgtaagaa ggcttcttca
    30181 tttaaggagc cagcctgagt ggcatgctct ccgataatct tgtgaagggc agcatgaagc
    30241 aggtgcgtag cggtatggtt tttctcaaca gcatagcggc gcttgtgatc aatagcaagg
    30301 gtataaacag tatttaatgc aaggcttgca aggacctcaa cagtgtggag cggctgacca
    30361 tttggtgctt tttgcacgtc tatcacacga gcaacagggt ctcccttatc atttttgata
    30421 accccatgat cggcaacctg accgcccatt tcagcataaa acggtgtctg ctcaaacaca
    30481 agcaaggcct gtccttctga aaccatctca ctacgctcat tatcaacaat gataacagat
    30541 aaacgagagt caatagtctc tgtttcgtat agaaattctg atggctcagt gatacctgcc
    30601 agtgtctcat tttgcatgcc cattgagcca cccttaacag ctgctgcacg ggcacgatcc
    30661 tgctgctcct tcatagctgc cttgaagcct tcatgatcaa tcttatagcc agcatcttct
    30721 gctaattctt ctgtcaattc aactggaaag ccataggtat catacagctt aaagatatcc
    30781 ttgccatcaa gcctgtcttg ccccttttcc tttagctgcg ccagcaattg atccaaatgc
    30841 cctgatcctg catcaatggt acgtgcaaag gtttcctcct cacgcttgat aattttttca
    30901 ataaagtcac gcttctcaag aatctctgga taataggact ccatgatatg acctacagta
    30961 gctactagct tataaaggaa ggtctcatga ataccgagcc tacgaccatg cataacagca
    31021 cgacgaagca agcgacgaag cacatagcca cgaccttcat taccaggtag ggcaccatct
    31081 ccaatcgcaa atgacaaggc acgaatgtgg tctgcaatga ccttaaagct catattatca
    31141 ccatcttggt cgtaagtatg gccagatagc ttttccactt ccttgatgat cggcataaat
    31201 aggtcggttt caaagtttgt ctttgcgccc tgcataacag ccacaagacg ctctaagcca
    31261 gcacccgtat caatgttttt gtttggaagc tccttgtact ctgagcgagg aattgtaggg
    31321 tctgcgttaa attgagacaa aacaatattc caaatttcaa tataacggtc gttttcaatg
    31381 tcctcttcca gcaatctaat cccaatatga tcaggatcat aagcctcacc acgatcaaag
    31441 aaaatctctg tatcaggccc tgacggacct gcaccaatct cccaaaagtt ttcctctagt
    31501 ggaatcaaat ggcttggctc aacgcccaga gcaatccaac gattgtaaga gtccttgtca
    31561 tctgggtagt aggtcatgta taatttttcc tttggaaaat cgaaccattc cggacttgtt
    31621 aacaattcaa agccccactc aattgcttca tcgcggaaat aatctccgat agaaaaatta
    31681 ccaagcattt caaacatggt atgatggcga gctgttttac caacattttc aatatcgtta
    31741 gtgcggattg acttttgagc attggtaata cggggattct caggaatgac tgacccatca
    31801 aaatattttt tgagagtagc cacaccagag ttaatccaca agagggttgg gtcatttacc
    31861 ggcacaagat ttgccgaagg ctcaatagag tgaccctttg atttccaaaa atcaagccac
    31921 atttggcgga tttgggctga tgttaattgt ttcatgatta agataccaag agcgataaga
    31981 gagactaggt atgattgtcc ttagcataag tagccttgag agacgatctc tactcgcatt
    32041 cagttccttt cgttgatttt tttatgggat taggctaaaa gccatcaaaa caaaacaagc
    32101 ccatatcaca gagggcgaaa accgcggtac cacctctatt caatgagctt gtcattctta
    32161 attacttata tcagataaaa tcacattaag cagcatgcct atcagattat ccgtaactca
    32221 cagcaaccgt cacttctctg ggtcaaatcc ttgataaaca attcttaacc aaaccagtat
    32281 aaagcttttt tgcacattcg tcaatgaaaa tctatttttc tgacttagat ttagaagatt
    32341 gactatcctt gcttgagtct gaagatgatt tctgatctga cttgcttgta ttcgccttgc
    32401 ttgctttttt atcggtattg gcatactgtg tcaagatatt agcaaaggct tggtctttga
    32461 tcttaacatt tgccttgtct aaggcctttg caatgacctt attttggaaa tcaatgtttt
    32521 gtgtcttttc agccaagaca atttctttta gacgtttctt atatttcttc caatcagaag
    32581 ccttttcggc ttttttggtt accttaacaa tatagaactt gttttgataa gtagccggat
    32641 ctaagacaga aaccacctct gaaatgtcac cctcttttaa tcctgaggcg gccttgatca
    32701 catctgctgg taacttagtg tctcctgagt caaacttata gtctaccttc ttgtctgctg
    32761 ctgttgtctt ttccttagca atagcaacaa agtcagcacc ctcagcctta acctcaccta
    32821 aaatagcctt tgctgtttct tcattgtcta gagtaatgac ctgagtagtc atttctggtg
    32881 tgtatgactc ataggctttt ttgtaatcag catctgtcag ctctttttta actgcttctt
    32941 taacagcata ttcaaccagc atggctgagc gaatttgacg cttgtaggta tctgttgtca
    33001 agccagactg cgcaagggct gcagagaatg acgcaccgta ttgctcagct gatttattgt
    33061 aagcttcttc tgtttttttc ttagaaacct ttttaccata ttggtcctca aaaacacgac
    33121 taaccacaag gtttagcatt gctctttgag aaatctctgt attttttgtt tcattgtaaa
    33181 agtcgctaac actgatagtg tcgcccttca tcgtaatgac acttgtattg tcatttgtag
    33241 actgacaggc tgctagggtc attgctgatg ctagggttac gataccagca agtaatttag
    33301 ttgatttttt catgtgattt tgtgctcctt tttgtcatta accagtatat tatatcacaa
    33361 tttcttaaac gtaacttaat ctaacaaacg aatatctgct tgatttttac gaatcatcag
    33421 caagccatca ctaagtggca gcaagctggc tgttaatcca ggattatcca aggttgcagc
    33481 aaataagtcc tgtaggccac gataaatcgt gcgctgtcct ctccgaacct ctttgatagg
    33541 cttagcaatg tcgcctcctt gaaagacatc atctaaaaca accattccac ctatttttaa
    33601 gtgctttaac acctctggaa gaaactgaat gtattttgat tttgcagagt ccataaaaac
    33661 aaagtcaaac tcgccagtaa gccctgctaa aagatcagcc gcatctccct caagaagggt
    33721 aatttgcttg cggttatcgt attttgcaaa attttccttg gcaaagccaa tcatctcagc
    33781 attgcgatca atcgttataa tctctgcctc aggaacgttt tctgccatta gcaaggcaga
    33841 aaagccaata gctgtgccaa tttctaaaat cctcttgggc tgcaagcttt gcaataacaa
    33901 tctgaaataa gcaacaacct catgctggat aatgggaata ttttcttgtc tggcaaaggc
    33961 ctcaagctct gctaaaaagc cttcgttttg cttttgctgc gttcgcatgt agtgaacaat
    34021 gtcttccttg acaatagggc ggcgcatatt atgatttgca tttttactat atgatttaac
    34081 catgctattc attatataaa aaaactctag gtaatgctag gtttttacta gccttttcaa
    34141 tttcaatgat cttggcggta tctatcaaag gagctcacaa acagccttga gctgctggac
    34201 aatgctatca caagcagata agtcctgtaa gggatagtca ggattggcaa agccgataca
    34261 ggtcatctga gcagccttag ctgcctgact gccatgctta gtatcctcaa tgacaagaca
    34321 ggtcttggga tcaacgctta accattcagc agccttaaga aaaatatctg gcgctggctt
    34381 tgagcgagca acctcttcac cactaactaa cacctcaaag cagtccaaaa gacctagtgc
    34441 agtgagattt ctaataatat ctgccttagg cgatgaggag gctactgcca agcgatagcc
    34501 cttcgcatgc aggtgcttga ttaattgaac agcacctgct atggccctga caccatcacg
    34561 cttaagcatt gcttgacgac ggtgattcat ctcagcgatg agggcttcaa cagaatcctc
    34621 tagctgacac tcctttttca tggttgtcca catatcgtca aaggtggttc ccataaactg
    34681 gtactgataa gcttcattgg tatctatgcc tcggtccaat agcatttgtg tcttggttga
    34741 caaaaagata tattctgagt caacaatcac accatccata tcaaaaataa ggcttgtttt
    34801 catcatctac ctccccttta tgctatatct cagtcaggtc aagagcaaga ctattaattg
    34861 ctggagctat ttttaccaga aaaaagctca gcaatgtctg atagctgact aatatgatga
    34921 ttatcatcgc tatctggcag caataaattg atcgagcaaa taccagcggc ccttgctgca
    34981 gcaagatcta agggcctatc accaatgtaa taggtctttg ccttagccat ttgatatttg
    35041 tcaatgagaa aaagaagtgc ctcaggattt ggcttgcgtt taaagccaca agctgctgta
    35101 atcacctctg taaaataatc agcaatgcct aagcgctgca aaaccgcctg agtggtctta
    35161 cccttatggg tcacaataaa gtgcttaacc ccctgctgag aggttaaggc taatgtttcc
    35221 ttggctgtag gcattagtgc tattaggtga tcacgcgctt cctgctctcg ggtaaagaag
    35281 gccagcaatt ctgaaaaatc cagctgatgt gcctctgcta acctcttcaa aagctgtccg
    35341 atggattctt gaataatcgt atccataacc caagcctcat caaagggcag ctgataggtc
    35401 tgatacagta gacgcaaggc ttgacgaata gcctcagagg attggacgag ggtcccatca
    35461 aaatcccaaa ttaaattaac cgtcactatc tctacctcct aaatcaatcc aataacgggc
    35521 gattgcctgc cctgccattc ttttagtagg gtaatcatct gctacctgaa taatatcctc
    35581 taaaatacca ccagcctttt caatggtttt tcgactggct atattatctt tattagctgt
    35641 tattaagaca cgcttgatgc cacgcttttg gtattgctcc agggcaaagg ctaatagggc
    35701 ggtcataatc ccctgtccac gataatctgt ccttgttaca tagccgatat gcccaccaac
    35761 ggttgccaag tctccttttt ccagctgcca gcgacagcct attctagcca ctagctgacc
    35821 atctaaaaaa tagtaataat tagtgctagt ggaccagtca ggatgatcag tttggacctc
    35881 aaaccgccta gattgctcaa caaaagctgc aaagtcctct actttttggg tctcaacaaa
    35941 ggtattgcct gaagcctttt cagctaatag tatgtcctga aagcgctcaa aggctgcttg
    36001 atcagctaaa gcaattgttc gaatctcttt catgcatcgc tcctcttata cgataacgat
    36061 caactagggt atttttctca agcatttcat catatcaact aaaaagagct gcccctagga
    36121 ttgttgatat aacatcatgc taggggcaac ccataggcct tgaagctagg ctaataaaca
    36181 ctgactgctg ctatttacca atagctcaaa acttaagagt agatggcaac tattagagat
    36241 gagcccctct tgccactaag tcctctagct ctgtcaaacg ctcttcaaag accttaaagg
    36301 ctgcttctag gtaatccccc ttagccatat caacaccagc cttggcaatc acctcaagag
    36361 gataatctga atttccagac ttcagataag tcaagtagtg atcaatatcc tcttgagtac
    36421 catgcacaat cttatcagcc aagtagctag ctgcagcaaa gcctgttgca tattgataga
    36481 catagtagtt gtaatagaag tgtgggatac gagcccactc atactggata aagtggttgt
    36541 cctctttctt taatccataa tacttttcat ttaaatcagc atatagctta ttgaggtatt
    36601 cacttgttaa cacctcacca ttttgatccg cctgatgaat agcatgctca aactcagcaa
    36661 actgtgtctg acggaaaacc gttccacgaa aaccatctag gtaatggttc aaaatagcaa
    36721 agcgctcctt gtcgtcctct acctcattta gcaaggcctc agtcatgatg ttttcattcg
    36781 tcgttgaggc aatctcagct aggaaaatgc tgtaatctcc atacacgtaa ggctgtgttt
    36841 cacgcgtaaa ggttgaatgc aggctatggc ctgtctcatg caccaaagta tagaggttat
    36901 caagcgtgtc ctgccaattt aagagcataa aggcatttgt atcataggaa ccaccagaat
    36961 aggcacctga gcgtttgccc ttattgacat gcacatcaat ccaacgctct gtaaaggcac
    37021 gatgcacacg ctctgaataa tcctgaccaa aaacagccaa aaccttctct gctttttcca
    37081 aggcctcatc atagccgata gcaagatctg tctcagataa aggagtataa acatcataca
    37141 tctttagatc atctaaacca agcacctctt gacgtagctt caaataacga tgaagcagcg
    37201 gtaaatgctt attaacggtt tctagtaggg tatcgtaaac agcctctggg ataaagttgg
    37261 ctgacatcgc tgcctgacgg gctgaagcat acttatggac acgtgcctta taattttgca
    37321 ccttgacatt ggtttgcagg gttttagcat aggtatgctg gaattgctca taggtgctat
    37381 acatcgcctc ataggccgcc tgacgcactg tacggtcttt agattccatt aggctaatga
    37441 aattaccatg tgttagctca acctcttctc ccttatcatt tgtcacaata ggaaaagcaa
    37501 tgtcggcatt atctaagata ctaaaggtct cctcagcacc attaaagatt tcttgtgccc
    37561 ctgctaatag ctcctcctca gcctgactaa ggacatgctc acgcgcctta aacaacttgt
    37621 caaagaaatg gtcatagact gctaattctg gcttttccgc taagaaggcc tgataggtct
    37681 cttgagtcaa gtccataaac tctggctcat aaaaagagaa ggcttcgcta aatttagcat
    37741 aaataccaga agccttagcc tgatattcct gatacttcgc aactgttgta tcctgatcgt
    37801 ttttcatgct ggcataaaca taaagctttt caacacgacg agccagctcc aaatgcagct
    37861 ctgtgatatc taagagactg ctgcttgaat ccaacaaatg cccagcctgc tgccttgcag
    37921 cctcaattgc tgccagcaga ctatctgcct ctgtctccca agctgcgtct gttgcaaaaa
    37981 tagtgcttaa atcccaagtg tacttttcct ctagatgact acgattatct gtcatacgga
    38041 cctcctaagt ttctgttatt aaacatttta acataatatg ctggtgaaaa aagcttttgc
    38101 acctctttat ttgctgcttt tgcgtaatat ttttcaaagc aatcgtaata gtggctcaaa
    38161 tcctcatgaa tctggcaaaa gccagatgag caagcaatcg gcttaacctg tggataataa
    38221 gcctctaggg gcctatcaag caggttatcc ccagctagat aagcctcttc ttgctttttc
    38281 aaccatttgc tatcttttgc tagtaaggct ttttgaatcc ttctcagcaa gtgcttatcc
    38341 atctggagct gataggctga caggcctttt ctttggtaag gcagccgcaa aaaggccaac
    38401 aaatcatcat ctaaggaaca ggtctttact agatagctga ccttaccaaa taaatcctca
    38461 tgaatcatat atttcaatcg tatcaggtgg tgttccacat cgagctccca aagatgaaag
    38521 ccaagctgcc aagaaaaata aaggcattgc ctttgtaaac ctgtcagacg cttttgcagc
    38581 caaagctttc ttcctaagag ccaacgcacc tgatagccat tagcctgata agccctactg
    38641 cgttgctcca gccttttgat tggtagctga ctacactgga tttctaaggc taagcgctta
    38701 ttaaccagaa ggtctgcaat ttgatttaga tcaggcaggt aggcctcaac ctctgctgcc
    38761 tcagagcgag ataggctacg gtacagaaca gcctttagcc tgagatgttc atgtgattca
    38821 ttttcagtca ggtattggca atgacttagg ctaatatggg caaagtgggg tcggataatt
    38881 cttccttttt tcaagcgtac agcagctcca caagcaggac aggtaaaggc ttgcttgcgt
    38941 gaggggagac agccctctgt aagcgagatg actctttgat cttggtccaa ggcagttagc
    39001 atagggttct ccagttctta tcgttctatc tatagcatat atccgaaaaa cactggactt
    39061 aacctgtcag tcaacttcaa atctaacaat attttatgtt aaataggtct tgatgagctc
    39121 tttttctttt actgttagct gacgataagc tccctcagct aaatccccta gcgctatttc
    39181 tgcaaaacca atccgtttga gctgtgtgac ctttaagcca tagcttaaaa acattttctt
    39241 gatctgatgg tattttcctt cagagagtgt tacttctgct tgtgactcca tttgatcagc
    39301 ctttataatc cgcaaggcgg cagacttgca gcgagtacca tcaagaaagg taacaccatt
    39361 ttcaaagaaa ggcaccgcat cagcagccaa agagccattg acagtcacaa ggtaggtctt
    39421 gttcacatgg tgcttcgggt gaagcatacg aaaccctaat ggaccattat ccgtcaagag
    39481 gacaagccct gttgtatctc tatctaagcg gcctataggg taaagattgg ccactctatc
    39541 ctccttacga atcaaatcaa tgacagtttg gtgcttccta tcagagcaag ctgacacaac
    39601 ccctgctggc ttatgaagca ggtaatagcg atgagcaaat gcctttattt gcctgccatt
    39661 taccattatc acttgaagac ctgaatcaac actctgacaa ccagctctag ctggttgccc
    39721 atcaatcaag acagaccttc ctttgatgag ttgtttcact tgatttctag aaccaaagcc
    39781 tgtcacttct aataatttat ctaaacgcat agcattagtt tatcacaata tgtctgaatt
    39841 ctaaaaaaga ggccaagaag cctcttttaa taaccgatca gatttttttg ctaaaaccag
    39901 cagagagctc tagccagatc cctacactgt atcaaaacag cacaacgaat agcagactag
    39961 ctgttagcca tcagcaatag tctaatccag ctctgaagcg gcagcctcat caataataac
    40021 cacaacatta tcgtgctgct gtaatacact tgctggcaaa gcctcagtaa ctggacctga
    40081 taccatgccc ttaatagcgg cagccttttc cttaccaaag gccaatagga caatcatttt
    40141 tgatgccatg atagaagcaa ttcccattga aatagcctgc tttggcacat catcaatact
    40201 agcaaagaag cggctgttgg cttcaattgt cgaagcctgc aaatccacca catgcgtctt
    40261 ttctgcaaaa gaggttcctg gctcgttaaa gccgatatga ccattgcgcc caattccaag
    40321 aatctgaaaa tcaatagggt gccctgcgat aacttgatca tagcgcttaa cctctgcctc
    40381 taagtcatca actaagccgt ttggtaaaaa gctttcctta aagggcttag cgttaaacag
    40441 ctggtcatgc ataaaatagt catagctctg atcattttca accggcagcc cgacatattc
    40501 gtctaagttg atactggtca aggctgaaca gtctaaatca ctattaacca gctcctgata
    40561 aaaggtaatc ggtgtgctgc ctgttgccaa acctaaggtt gtagcccctt ctgccaagct
    40621 ttcctttaat aggctaaaag caaccttgcc accctctaac tgatcctgta cacgaataat
    40681 tttcatctga ttctcctttt tgattggtat agaccttttg tggttctatt atatggtata
    40741 taccaattat tgtcaagcca taatctcata tcccatgtcg tcagctaaga agcactagct
    40801 aataaggagc taaaagccac caatcatctc tatatgtctc ataaccatga caggtgacgt
    40861 agccagggac aagtgatata atagaaagga tttatctcta aggatagata ggctgattgt
    40921 aaatagcctc acaagaaggg taaaggagtt aagatgaata ccaacgattt tgattttgag
    40981 ctgccagagg agctgattgc acaaacacca cttgaacaaa gggatcgctc gaagctcttg
    41041 attatcgacc atcaagagca caccatgaca gatagccatt ttgaccatat cattgatcaa
    41101 ctagagccag gagatgcact ggtcatgaac aatactcggg tccttcctgc ccgcttatac
    41161 ggtgaaaaaa tggaaacaca tgggcatgtt gagcttttgc tgcttaaaaa cattcaggga
    41221 gaccaatggg aggttttagc caagcccgca aagcggctta aagccggtgc acagatcagc
    41281 tttggtgatg gacgcctaaa ggcaagggtc attcaagagc tagagcatgg cggtcgaatc
    41341 gttgagtttt catacgatgg tattttccta gagattttag agactctagg cgaaatgcct
    41401 cttccgccct atatccatga aaagctagca gacgctgagc gctaccagac cgtttacgcc
    41461 aaggaaaatg gctcagcagc tgctcctaca gccggactac actttactca ggagcttctg
    41521 caaaaaatag aagccaaagg agtacacctc gtctacctga ccctccatgt tggcctagga
    41581 acctttagac cagtttctgt cgataatatc gatgagcatg acatgcactc tgaattctac
    41641 ctgctatctg aagaggccgc ccaaaccctt aggaaagtta aggccgctgg tggacgcatt
    41701 gttgctgttg gtactacttc tattcgcaca ctagaaacga ttggcagcaa attccaaggg
    41761 caaattctag cagattctgg ttggactaat atttttatta agccaggcta ccaatttaag
    41821 gttgttgatg ctttttcaac gaacttccat ctgcccaagt caacgcttgt catgctagtt
    41881 tctgcttttg caggtcgtga ctttgtcctt gaagcctata agcatgccat tgatgagcat
    41941 taccgcttct ttagctttgg tgatgccatg tttgttaagt aaagcctaat gatgaaatac
    42001 attcacagca ggctcatgtt tttattattt gtgctgtttg ttgttagctt tgcaaagcat
    42061 gagcaagcaa ggctggcctt tgagcagagc caccaagctt acaaggacat ggttatttcc
    42121 tttgaaaagc ggcatataaa acaacagccc tcaagcctat ctgatcagtt tcagctcagg
    42181 aaagatctgc tgcattatgc caaaaagcta gcacaggacg ggtggtccta tgaggccatt
    42241 gaaaagggct acctagacca tctcaagcct aagcaagcaa gctataactt tgagcagctt
    42301 tatcagagtc tacaggtcat tgggtctcct gcttttcatc gcatgtggga aaggcagcca
    42361 agggctcaac ataagcttga agctaaaaga gacctcaact tacttttgac ctatgtaaaa
    42421 atgcccgaag aattaagtgg gcaaagcgct gaaacaaagc aattgcttaa gcaattcagt
    42481 ccgtccttaa gcccgacaga tgccttttgg gaccaattgt catcactagt tcagctttat
    42541 tatgatcatt tggagcatat tccttatcaa accttcaacc gcaagctcta tcagctgcgc
    42601 tatgtcctgt cagtgcagca aatagaatgg gttagaaaca attatgggag agcaggaaaa
    42661 acagatgctg atgccttggc tagataccta gctaccctag acgaatctga ttatagtctt
    42721 aatgaatcag ccagatacca caataaggta gctagtcatt tagacacagc caatcagctc
    42781 caaatcacat acccagacaa tttcccccaa gccaattata agattttaat tcattttcac
    42841 tcagaattta ttttatcaga ggctggtcat ttcttggctg ccctagatcc tcaacagcca
    42901 agtcaaaatg gtctcatcaa tgggtcttct tttaactatg ccaatcaaaa caacgatctg
    42961 catagattgc ttgatattga acccattgag ctatttgagc ctgatgtcat tgaaacagca
    43021 atgataaacc ctaatagccc atttatagta ccggatttag agcagcaaaa tgatcaacag
    43081 caccctattt ttagccgaga cggcaaatcc tccaagcaat taacaaaaat ggcagctaaa
    43141 gcctttaaaa aattacttcg ccattatcaa caagctcatc aaagctttcc cagcaccccc
    43201 cctagctgag gtatgaggta gatccaataa ccaaaaaaca gctctatcat ctctctagtg
    43261 ggtaaactcg ctagagagat ggcagggctt tttataaagc ttctaagcta tcaaatacac
    43321 tctgaacgtt acacgtattg tctatcacgt tagagaatat tttcaaaaga cttggaggct
    43381 tttaccacca acactagtag tttattagca cacttaaaaa accaatctac ttctgataat
    43441 aacatatgat atcaaatcca ccatatcact aagttgtctt aaaacaatgt tttataaaag
    43501 tgaagcttta ggtcattatt tgatattgaa aagtgaaaaa gctggaaaag ctttttcatt
    43561 ttccagctta gatgacaaca taacgtaaac tcttattgat tagcgctttc acattgtgaa
    43621 taatatactc ctaaattcct cagtgtatat tcaaactgat ctttttcatc ttctgtcata
    43681 acttcaatat gcttgatatt ttctaattct tcctgtgcct gactaactag acttccgact
    43741 atttctttta acctgtcagt tttgaactca gcctttaaag cactcgttct tatgatgaat
    43801 tcattatact gctcaattaa ggcttcgtat taaccattta attgtactga atcacttact
    43861 agagcttaac tatccatctc ttttagctct ccatcttttc taattaaatc aggatctccg
    43921 tcttctctaa tacactgcga ataataaata tttaaccact ctaacacagt tttggacttt
    43981 ttgtagtcgt cctcttcaag atcaggactt aaggttaatt ttgctagctc atttttagcg
    44041 tcctcaccta gtccaataac taactttttg aaatgctctt tcttaaaata gctactgata
    44101 ttttcaacct taaagacaaa tttcttcagc ttatctatta acgattgctt ctcagcctct
    44161 tgtatgtatt taaaatcatc ttttgcaacc ttattacgta tattcgcatc ttgattaata
    44221 aataatagct ctttcgtgtt gtgtgagagg atccaatctt caaaatcctt atagatctcc
    44281 atatagccac gatctaaatc aacgtttgtt tccttagtta aatcaaaaat cttataatcg
    44341 tgcgtattga gattgtcata atgctcttct gtgtatttcc ctctaccaac tcctgtaaca
    44401 tctagtgttc tccacttttt atcgtaaaaa acacgtatcg ccgcatgtgc tgcgccattt
    44461 ctatttctac cataagtcac ataagatggt atccctaata aattcagtcc tcttgcagcc
    44521 gctgtactga atcctataca catggcctta tttcgctctg taagtgcaaa caaatcagaa
    44581 gcctgacaaa atattaaata atcaggatta tatcttgctg cctcccaatc ataatcaaca
    44641 tggtttgcca tatacaagac ataggctttt actcgttgag catctgtcag cccctctcga
    44701 tcagctccag atgttacaat caattccttt aatttgtcat cattcctctt aaaacgttca
    44761 aacgttatat ggctgtcttg cttataatcg tctttagtat acctataagc aaattgatta
    44821 tcaatacgca gatgctgcgt atgaatagta acaccattta tacctagtat tgagtctaag
    44881 cttatcgaat cagagagtga aaggccgttc gcttttagta ttaagtttag ataaggatat
    44941 ttatccttta gctctgcatc aaaggtatag tgtatagtag gataatcaaa cttttctaga
    45001 tttgaaaacc tttctgctat tacgcggtca tattcttctt tagttgatac cagctgatct
    45061 tcctttttca tcatgaaaaa tgctctgcca tgtatcgcct tcccattcaa ccgcacaggc
    45121 ttataatctt ttatgtagtc accaagacga tcaggaaaca cttcactata ttttggactt
    45181 ccctctccca agatatagat ttctaacgcg tcctgatgat ttttggctaa ctcagactta
    45241 acctcgctaa tcaggtttga cacagtgtta tctaaaacga ccgtcgattg ctcgctaagc
    45301 tttatatcgt ccgcagctac agctgttccc ttgacgacta aagacataga tatagcacca
    45361 catgctaatc ctaatagtaa tcctttacac aaaat
//
LOCUS       DARYSY010000013        44935 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYSY010000013 DARYSY010000000
VERSION     DARYSY010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44935
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(59..416)
                     /locus_tag="TVR04_000609"
                     /pseudo
     CDS             complement(59..416)
                     /locus_tag="TVR04_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516374.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(643..715)
                     /locus_tag="TVR04_000610"
     tRNA            complement(643..715)
                     /locus_tag="TVR04_000610"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(680..682),aa:Lys,seq:ctt)
     gene            complement(717..910)
                     /gene="ssrS"
                     /locus_tag="TVR04_000611"
     ncRNA           complement(717..910)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TVR04_000611"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(996..2267)
                     /locus_tag="TVR04_000612"
     CDS             complement(996..2267)
                     /locus_tag="TVR04_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1269322.1"
                     /translation="MPDNLTIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTENPFFSVTPAIRSRVQIFELEPLSYEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDNEGIRHISL
                     DIVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYPGSKELGNAQHYLYPHAYPEKWVKQQYLPDQL
                     VKKNYFDPNETGKYERALAANKARIDKLSSS"
     gene            complement(2260..2868)
                     /locus_tag="TVR04_000613"
     CDS             complement(2260..2868)
                     /locus_tag="TVR04_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1269323.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDCEDSEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(2909..4645)
                     /gene="pabB"
                     /locus_tag="TVR04_000614"
     CDS             complement(2909..4645)
                     /gene="pabB"
                     /locus_tag="TVR04_000614"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1269324.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     GLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDNCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMKQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGTLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESRWQDEFEEIKQKSSFLHRQSIDFTIKTTAKVEQQNLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTYQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELRLSDLDKAEAIFGSNAVRGL
                     YSLTIEDTTLPQ"
     gene            4799..5269
                     /locus_tag="TVR04_000615"
     CDS             4799..5269
                     /locus_tag="TVR04_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1269325.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLGYF
                     AQFLNDVAIEGHSDLMDFLADDSQLDFSLEWNAEAFEEGQIGLEEGARFPYPRY"
     gene            5271..5615
                     /locus_tag="TVR04_000616"
     CDS             5271..5615
                     /locus_tag="TVR04_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1269326.1"
                     /translation="MQHEMMLTPRPFAMIEAGLKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSQILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            5632..6060
                     /locus_tag="TVR04_000617"
     CDS             5632..6060
                     /locus_tag="TVR04_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1269327.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(6258..8795)
                     /locus_tag="TVR04_000618"
     CDS             complement(6258..8795)
                     /locus_tag="TVR04_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1269328.1"
                     /translation="MKQHKRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKAAK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPSPSQAAKASSTAAVSHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATIHHIAATTPHLPSTPPVIHQQGGIPGLDFQTSDGFLFDG
                     NNISSVTDTGILVKHGDHLHPISFEDLKRSKWAYLVEQYKSGQTKAPQGAYHAQIAYL
                     AAGLKIDPSRIKQILANDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRNGVYQKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNEVTGNSSHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            9355..10308
                     /locus_tag="TVR04_000619"
     CDS             9355..10308
                     /locus_tag="TVR04_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1269329.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGCQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELILTNQEL
                     AEEDWADNWKAYYESARITHDLTIVPSWTDYEATAGEKVIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKAEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            10308..11054
                     /locus_tag="TVR04_000620"
     CDS             10308..11054
                     /locus_tag="TVR04_000620"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1269330.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDMEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELADLSPGQKVLFIFGPEGGISPKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALEMIPH"
     gene            11300..12553
                     /locus_tag="TVR04_000621"
     CDS             11300..12553
                     /locus_tag="TVR04_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1269331.1"
                     /translation="MKKVITNRLFMATFVSDMLSNFGDVLYYLALMNMVLLVPETKLA
                     IALVTVSESFPYLTMVFMGMWGDKTRNKVDRILATQLFRVVLYMIVAYAMGSKPALWI
                     VIVAVLVNVLSDLSGQYENALYMPLSLRIVSDEDREAMYAFRQGTSSVLRIIFQSSGA
                     LLVGIMTYQQLAFFNAGTFLVSAVIMLVLRPSLLRLLKKSPISFAESTSTANPLRHFV
                     SDLWKALKEAFIAVDKIPSLKASILAIAGLNAIFAAEDALILLTIREHADFMIINPAV
                     TLAAFSISSLAGMISGSILITGVFKEVSFKLLLRAAVLMSLLLFVGYLCHAVGFVLLI
                     HFLALTICGVFNPKMNALVVRSLPENRLATVGAGIDSFCTLGMVVSRWTLSVLVTVLS
                     AGTISLIFILLSLALLGYTISIKKY"
     gene            12573..13610
                     /locus_tag="TVR04_000622"
     CDS             12573..13610
                     /locus_tag="TVR04_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEL1269332.1"
                     /translation="MNIIYSETASELVEQFYFPQFAVSVSDWEWDFTNKERGLLRDVW
                     PILEELFDLFSPYKEKIASYCLLSGSGSILHACLLDMLKKGLAPKTVKAVYAYCLELS
                     EDQVRQLLIDMLNTEAEPMDKASFWECLEMSSKKPEDKWHFSRFYRHPLESMKELVEL
                     SRELILLYQPYLEKGRAERQAYAKTFLSEGFLEGLFSRFNVAFDENETIYLHIVSPWI
                     IRLSISSDISQNEGQTRWSLVASSRIDQLIESRREIDSDSFANTLKILSDATRYNVFV
                     ALTKPHAKSKDIAKDLAITGAAVSFHTQKLINAQLLVVNRDDKDIKYNPNKALLKEVI
                     AKLETDFALGD"
     gene            13731..14735
                     /locus_tag="TVR04_000623"
     CDS             13731..14735
                     /locus_tag="TVR04_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1269333.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            15031..17217
                     /locus_tag="TVR04_000624"
     CDS             15031..17217
                     /locus_tag="TVR04_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1269334.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPIL
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADMLENDDTRPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGVQAVYGPKADILKSDIQDLLDSGAVIPELKPAQLA
                     ASSSGQTDFKNLTETVLTVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLAAITAAGRKTTVVVAFTNTTSIKAVNLVALGQQKAKTLVAQVEL"
     gene            17295..18116
                     /locus_tag="TVR04_000625"
     CDS             17295..18116
                     /locus_tag="TVR04_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1269335.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAALSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDSREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVISDHYGLEVDLDWKL"
     gene            complement(18411..18869)
                     /gene="nrdI"
                     /locus_tag="TVR04_000626"
     CDS             complement(18411..18869)
                     /gene="nrdI"
                     /locus_tag="TVR04_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1269336.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(19265..20449)
                     /gene="sezV"
                     /locus_tag="TVR04_000627"
     CDS             complement(19265..20449)
                     /gene="sezV"
                     /locus_tag="TVR04_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1269337.1"
                     /translation="MDTMSLVKSLQACLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDREQLTNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSITTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            20699..22390
                     /locus_tag="TVR04_000628"
                     /pseudo
     CDS             20699..22390
                     /locus_tag="TVR04_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            22614..24833
                     /locus_tag="TVR04_000629"
     CDS             22614..24833
                     /locus_tag="TVR04_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1269338.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVACGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAIHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDAIEGYITKG
                     RGIAIHRADCHNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            24848..25291
                     /locus_tag="TVR04_000630"
     CDS             24848..25291
                     /locus_tag="TVR04_000630"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1269339.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNLSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNDHLEELVPVKRGVFGADMQVSLINDGPVTIILDTKHR"
     gene            complement(25418..26719)
                     /locus_tag="TVR04_000631"
     CDS             complement(25418..26719)
                     /locus_tag="TVR04_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1269340.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKISKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIVDANRIAQAYSPSYDVTDPLTYAS
                     HQDIVTETYFISKDINDDYSTTYRPVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KHHTGLLDTFQAKNGTTYQFTGSLTPISETEFIAVYKDLQK"
     gene            27474..28322
                     /locus_tag="TVR04_000632"
     CDS             27474..28322
                     /locus_tag="TVR04_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1269341.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVEEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLADLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKVAQQSGLHLKQLDDLAFAY
                     LFILKH"
     gene            28472..29605
                     /gene="ugpC"
                     /locus_tag="TVR04_000633"
     CDS             28472..29605
                     /gene="ugpC"
                     /locus_tag="TVR04_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1269342.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            29789..31408
                     /locus_tag="TVR04_000634"
     CDS             29789..31408
                     /locus_tag="TVR04_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1269343.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIADIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLTSIFSGSAWEYDDASGQYYLHLFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNAPKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDS
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLQTSDKVFAYKRQLGREIYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDEAL"
     gene            31517..31879
                     /gene="traF"
                     /locus_tag="TVR04_000635"
     CDS             31517..31879
                     /gene="traF"
                     /locus_tag="TVR04_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HEL1269344.1"
                     /translation="MTVEETMTFAKSIAAFRQVEISEVVTRLAAGEDITVFLGRATCP
                     YCRRFAPKLASVARQEHKDIFFVDSEDSTELADLQAFRERYGLATVPALLISRHQEVK
                     AVCDSSLTEEAILAFLEQ"
     gene            31993..32352
                     /gene="yajC"
                     /locus_tag="TVR04_000636"
     CDS             31993..32352
                     /gene="yajC"
                     /locus_tag="TVR04_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1269345.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTEPAVD
                     DTAVEASDEAESAIETN"
     gene            32526..33275
                     /locus_tag="TVR04_000637"
     CDS             32526..33275
                     /locus_tag="TVR04_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1269346.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            33285..34079
                     /locus_tag="TVR04_000638"
     CDS             33285..34079
                     /locus_tag="TVR04_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1269347.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGTVISSDSY
                     GFEDASFPIAASLYVGVGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            34111..35376
                     /gene="rseP"
                     /locus_tag="TVR04_000639"
     CDS             34111..35376
                     /gene="rseP"
                     /locus_tag="TVR04_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1269348.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQG
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDETKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            35646..37502
                     /locus_tag="TVR04_000640"
     CDS             35646..37502
                     /locus_tag="TVR04_000640"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1269349.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKPSSKVTALDDLIEIETPNCKTIDEVAAFLDITEHQVIKTLLFMADHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEAHTILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDGHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTEKVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            37554..38111
                     /locus_tag="TVR04_000641"
     CDS             37554..38111
                     /locus_tag="TVR04_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1269350.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLSLKDCWLAAGAVRNTIWN
                     HVAYGTGFDSLTDVDVVFFDPEISYQDGQLLEEQLKCAYPMYQWELRNQVYMQKHSPK
                     TPPYQSSQDAIAKYPERCTAIAVRLVRGQVEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHNC"
     gene            38446..42843
                     /locus_tag="TVR04_000642"
     CDS             38446..42843
                     /locus_tag="TVR04_000642"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1269351.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFEINRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEGAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            42965..43393
                     /locus_tag="TVR04_000643"
     CDS             42965..43393
                     /locus_tag="TVR04_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1269352.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            43523..44068
                     /locus_tag="TVR04_000644"
     CDS             43523..44068
                     /locus_tag="TVR04_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1269353.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGEAAVSYLDWGQVPI
                     FSQDLEASTPESVASVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIN"
     gene            complement(44195..44809)
                     /locus_tag="TVR04_000645"
     CDS             complement(44195..44809)
                     /locus_tag="TVR04_000645"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1269354.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILE"
BASE COUNT        12448 a         8898 c        10617 g        12972 t
ORIGIN      
        1 cttcaagatt aagttcatta ttaagctctt tagttgttag agtgtcttta tctaattaat
       61 tttgaaatat tgcaaaatct agaatttttt gaagtaatac ttcttcctcg gccatacggc
      121 tataaagcca attattttcg agtctctcta ggtgctccat ccacttaaag tctctttttt
      181 tctcctagca tattgtaggg aaataaggta tcaatatcaa catttaaggc tgtagcaatc
      241 tcttgaagcc tatcccatga aggttcagta gtcccctttt cgtaattaat aattgtttgc
      301 ttagtaactc ctattaattt agcgagttct ttttgagttt ttccagcttt taagcgagca
      361 tttttaatat ctatttgtcc aacttttaaa gcctgcgaat aatcaaaaaa agccattttt
      421 ttccaaattc cgtcgcaggt gatgaaggtg aaaatactcc gattgtatca ccttgtgtta
      481 attatattat tgtcatgtgt tagctctctt ttttaaaagt aataaattct ctatttaaca
      541 tcatatcata aaaaattgtt tcggggacaa atggtgggac aaaccttctt taagacaagc
      601 aaaaaagccc tgtaataaag gctttttgtc gtttttacac tataccccct acagggctcg
      661 aacctgtgac ccatagatta agagtctact gctctaccaa ctgagctaag gaggtaagga
      721 aagctgtatt ggcaccggtg attcacgttt tgtattgaac ccgcacgata taagcaggtg
      781 ggcaacatac ttctcttcag attgcttccg cgtgaaacgg cttgcatact agagatagac
      841 tttgtttccc taaaatacaa aaaaatagtc ggtcaacact tagatgtgaa ttcgtatgcc
      901 acagcaataa ctctatgctc ttatgatacc actttttgaa aatttttcaa gccctaaaat
      961 gaaaaaaaga tcgtatttct tgttttttct ttaggctagc tgctagaaag cttatcaatt
     1021 cgcgctttat tggcagctaa ggctctttca tattttcctg tttcattggg gtcaaagtaa
     1081 tttttcttaa ccagctgatc agggagatat tgttgcttga cccatttttc tgggtacgca
     1141 tgagggtaaa ggtagtgctg agcattgcct agctccttgc tgccgggata atgcccatca
     1201 cgcaggtgtc taggaatggg aaggtggcca tgttgacgta aatcagcgag agcagcgtcc
     1261 atagccatat aggcggaatt ggactttggt gacagtgcca gatcaatcac aacattggca
     1321 atgaggatac gggcctctgg aaagcctatt ttctgggcgg cttcaagtgc agtaacggta
     1381 tggatttggg cctctggatt ggcaagacca atgtcctcat aggcgataat ggtcaagcgt
     1441 ctagcaaggc ttggaaggtc acctgcttcg accagcctag cagcatagtg caagctggca
     1501 ttaacatcag aacctcggat tgatttttgc aaggcagata gtatatcata atgtccatcg
     1561 ccgtctttgt ccattgtgat gtagctgcgc tgcaaagaat tttcaacaat atctaagctg
     1621 atatgacgga tcccctcatt atctggctgg gtagacatga cagctaggtc aagggattgg
     1681 taggcagctc ggagatcccc atttgtcgct gtagcaataa aatcaaaagc agcctcatct
     1741 agggttacgt caaaggcaaa gcctctctcc ttatcggtaa tggctagctt aagcgcctgc
     1801 ttgatctctt catatgatag aggctctagc tcaaaaatct ggacccgact tctgattgct
     1861 ggggtaacag agaaaaaagg attttctgtg gtagccccaa tcatgataat gtgcccatgt
     1921 tctaaaagtg gcagcaaaaa gtcctgctta ctcttatcca atcggtgaat ttcatcaagc
     1981 aacagcacta gcccacctga aaatttagct tcctcagcga tttcttggag gcgtttttta
     2041 ttgtctatgg tagcattgaa ggttctaaag gcgtacttgg ttgttccagc aatagcacta
     2101 gcaattgatg tctttccaat acctggaggt ccgtaaagaa tcattgagga tagtctatta
     2161 gccttgacca tgcggtcaat gatttttccc tctccgacca gatgctgctg gccgatgacc
     2221 tctgtaatgg ttctagggcg cattctgatg gttagattat caggcattgt attcctccct
     2281 tccttgcttt tgttggctgt ggtgcttttt aacaacagcc ataaagtttg cgatcattgt
     2341 cctaccgtca gctgttccga tgctttctgg gtgaaattga aggccaaaca gtggcagctg
     2401 tctgtgttca aaggccataa tctcactatc ctcacagtct cttgcggtaa ttacaaagtc
     2461 agctggcagg tcatcaacaa caatagaatg gtagcgcatg acggttaatt gctttggcag
     2521 ctgttgaaag agcttagctg gtgcttgtct ttcaagtata ctttgcttgc catgcatgac
     2581 gcgcttggca agacgtagcc tgccacctag agcctcagcg atagcttggt ggccaaggca
     2641 aacgccaagc ataggctttt ggtcataaaa ggccctaatc aagctaggca tctgattggc
     2701 ggctttgggc cagccgggac caggtgagag gactatggcg tcagcctgct tcgcaaggtc
     2761 aaatagtttt ggatcctgat tggtcaatac aatcgtttgg tcaaaggcac tgaggtattg
     2821 ggccagatta taggtaaatg aatcgtagtt atcaattaaa agtatcataa ggtccttcat
     2881 ctagtagtgc tgagggatca gcctggtact attgaggcag agtggtgtcc tcaattgtta
     2941 gtgagtagag tcctcggaca gcattgctac caaaaatggc ttcggccttg tctaaatctg
     3001 aaagccttag ctctttttcc tgagccagtc cctgccttag caattcttga cggaaaatgc
     3061 ctggtagaat accggctgat acaggcggtg tataaagggt ctgctcgatt tgcacaaaaa
     3121 gattaccaat agaggtttca agcaaggtcc catcagcagc aacaaagact tgctcatagg
     3181 gcttgacgct cagatgtggt cgatgactgg ttttaaaata agtaaaggga agctttttga
     3241 catcgcttga ttggcgaact aatcgtgcct ttaaaaagtc tttttgaagc ggctctaagc
     3301 tttggtatgt aaggctaatc tgcccgtcct tagcaatagc aatagtgaga cgataggggc
     3361 tgctgtcctt tcccttgaga taggcttgca aacgatctgt cagaagctct tcatcataag
     3421 ggtaggcaaa ataacgcgcc gcctccctta gtctgttgag gtgttggtct agatagatta
     3481 ggttttgttg ttcgaccttg gcagtggttt tgatggtgaa atcaatgctt tgacggtgca
     3541 gaaaggaaga tttttgcttg atttcttcaa attcgtcctg ccagcggctt tcccaggtaa
     3601 tcccaccgcc taccccgtag atggcctgat cgtagctgag ctgaatcgtt cgaatagcga
     3661 cattgaagac acgtctgcca tcaggcaggc aaataccaat gctgccacag taaacacccc
     3721 ttggcttagg ctctaatcgg ttaataatag ccattgtaga caccttagga gctcctgtga
     3781 tggagccaca gggaaagagt gcctgtaaaa tatcataaag acgacactga tcctgcagcg
     3841 tgccgacaat ggtagaggtc atctgccaaa cggtggaata ttgctccaat tggcagagct
     3901 gtgtgactgt gacactccca gtttgacaga tcttattcat atcattgcgt aataaatcaa
     3961 cgatcatcat gttttctgaa cggttcttag gatcggcctg tagccagtca tgctcttgtt
     4021 gatctagttc taaattgtaa ccacgcttgg ttgtgccttt catggggcgt gtggtgatct
     4081 ggtttttctc ttgcttgaaa aatagctcag gactggctga aatgacagca aagtcatcgt
     4141 gagcaatgta ggcattgtat ccagctgcct gttcaatgac caattgatga taaatagcca
     4201 agctgtcctt agcgtttagc ctttggctga gctgaatggt atagttgacc tgataggtat
     4261 tgccctgctt catctcctga tgaatctgtg caatagcctc ttgataggct tcctcttgtg
     4321 tagcacttgt ccagctgttt ggaatcgtca tgctgtcgtg gtagagtgga aagtcctcga
     4381 gctgacaatt gtcatgcact gtaaaataag caaaatattc ctgaccaagt cttttattgt
     4441 gtgttgttag ctttttgtca aaacaggctg ctgcttcata gctgaggtag cccacaacat
     4501 agtagcccag accttgaaat tggttgacct gctcaaggac ctgtcccacc tgatcaatct
     4561 gcttagctac taattccacg ataggagctt gaaatatata gcgttgtccc agctccttaa
     4621 aatcaataat cgtctttata tgcatagctt gattatatca taaatgcgct tttcagactg
     4681 attaggagga gggttgaaaa gaagcctgtc agcaaacctc aacaatacaa gagagagcag
     4741 ggcttcttga tttatgctac aatagtagcg gatattattt agaaaaagga acaagagcat
     4801 ggctaaatat ggctttttat cagtattaga agaagagatg gacaagcatt ttcattatga
     4861 ctatgctatg gattgggaca agaaaaatca tgcggttgaa atcacccttg ttttagaggc
     4921 tcaaaatcag tcagcagttg aaaccattga tgaccaagga cagctcagca aggaagacat
     4981 tgtctttgag gattatgtct tattttacaa tccggagaaa tcacagtttc aagcagcaga
     5041 ctatctggtg gctattccat ttgagcctaa aaagggcttt tctcgtgaat tcctaggcta
     5101 cttcgcgcag tttctcaatg atgttgccat tgaagggcac agtgatttga tggatttctt
     5161 agcagatgat agtcagcttg attttagctt ggaatggaat gcagaagcct ttgaggaagg
     5221 gcaaataggg ctagaagagg gcgcgcgctt cccttatccg aggtattaag atgcaacatg
     5281 agatgatgct gacaccaaga ccatttgcta tgattgaggc gggtctgaag actattgaac
     5341 tacggttaaa tgatgagaaa aggcaggcta ttaaggtagg ggattggatt tgcttttatt
     5401 gtacagagga tcatagccag atcctgcaag cagaggttgt agggctgcat tattttgatg
     5461 actttgctaa gctttaccaa gcattgcctt tagaaaaatg tggttatcgt aatgaagaat
     5521 tggcactggc tcggccggag gatatggaac agtactacag caaagagcag caagcccaat
     5581 atggcgttgt tggtattgag ctaaggctat gttgattggt gagatctagt catgaagctt
     5641 ttagataaaa cagtccattt ttctggtgca aagttagcct tgatcagtaa cggtaagatt
     5701 ttgaccatct tgcgtgacgc gataccaacg attccttacc ctaatatgtg ggatttacca
     5761 ggaggtggtc gtgaaaatgc tgaagctccc tttgattgtg cgtcacgtga gtgctatgag
     5821 gagttaggtc tggcactgac taaggacgct gtcgtttggg aaagggttta tccagggctt
     5881 gttaatcctg acagccaatc tgtctttctg gtggctctta tgaatcagga catgatagat
     5941 catattgctt ttggtgatga ggggcagggt tatcagctga tggctattga tgacttttta
     6001 gcagacgatc gggtcattcc tcagctaaag gctcgcttag ctgattattt aagaaaatag
     6061 gcagatctag ctggtacact aaacagatca gcaaacacca ctactatgtg atagctacga
     6121 ccagaatcaa aaagacgatt gacctctgcc cacatgtggc taggatcaat cgtctttgtt
     6181 tttggggtgg ctaagtcttt aatctggtag gtcagatcag ctgagcagtt gatattatca
     6241 atcagtcctg ctatggctta gctgttgcta gctactgatg tgctgctagc tgtctctgac
     6301 tcacctaaaa aatagctggc tggcttatca cttactggcg tcttaccaac aagctcaggg
     6361 tcaggtgcta ataggtcgtc ctcgtcggag tcagaaacgg gtgctacaaa ttcttctagc
     6421 cagcttccag tgctaccagt atgattagga gtttgtggtt ctttaggtag tggatcacct
     6481 ggtagccagg tattccctga gtggctacta ttacctgtaa cttcgttgtt ggttatttta
     6541 tcaaagttga cgttataaac aatatcctca gtgacttcct tatcatattc ctcagttgaa
     6601 ataataggct tattgtaatc acgcttgtag ccggcatctg gctgtactga tggtggtagg
     6661 ataccagctg tatgtaatga gtgtccctta cgaacaaggt aaacggcagt cttaccctta
     6721 ccagctcggc taatcagctg tccgccctct cctgccttaa aggcaacggc tacatagtgt
     6781 ctcggatcgt ggaagtaata attagggtgt ctgctaggat cctctagatc agttggcttg
     6841 tcaggattaa cagcgatgta aggtccaata taaggagcag tagttccaaa ggctgctgag
     6901 aataggccag taaaggctac cttatcgttt tcattttgtg tgatagaaaa tctcttagca
     6961 aaatcagtta gattaaagtt attggcaagg ttcactccac tgcggtactc aataaattca
     7021 tagcctggat ctgggacggg ctcagggata acaagtcctt gctccttagc ttccttccag
     7081 gtaagaccac tacgaacatt gtagaagaag cctccttgag tcacgccgtt aagcttcaat
     7141 cgcccattaa agattgtggt gaaccagaca ggaacataat tttctaagtc aaggtctgaa
     7201 acatcatcac ctggcccgta gacagccttg gtaggctgct ttctaacctt atcaaaatct
     7261 acatagaagc gttgatgttc tctgtccatc ttgccagctg ttggcaactc agcactccag
     7321 cccttaaaga tacgcccctc atgcttgatt gcctctggac gctgaatgtt caaatccttc
     7381 cagtccaaat ccttacgaac caaatagtgc acacgtttag ttttaatgcc attaacctca
     7441 atgtcgccgt attcactatt tgtactaaac aacacatgga taaagttttt gatgtttttg
     7501 atgccttctg ggtgatattt ttgataaaca ccgtttcgtg tcaggttttc agatgaattt
     7561 tccgtataga aaggaccata aacgagctga gtttcgacct ctagattggt tgattctgtc
     7621 ttgacattgc gctcaggatc atctggcaat tctgggtcaa tcttatagat gtgagcatgg
     7681 tccccatgac taatggtcat gtagttgccc tcaattgaga tgtcctcacg acgaaccttg
     7741 aagcgatcca taaattcttt gatgagtctt tctttgcgct gttcaaaggt ttctccgtct
     7801 atctttttga ggatctgttc ttctggagtt ttaaatggct tagaaagatc aatatccttt
     7861 agccagatga cgtgcgtgtg gtcctcgtga gggtattcaa agccgacctg cccatcatta
     7921 gctaggattt gcttgatacg tgaagggtct atttttagtc ctgcagctag ataagctatc
     7981 tgggcatgat aagctccttg tggggctttg gtctgacctg acttatattg ctccactaaa
     8041 taagcccatt tgctacgctt taagtcctca aagctaattg ggtgcaggtg atcaccatgc
     8101 ttcactaaga taccggtatc agtgacactg ctaatgttgt tgccgtcaaa taggaagccg
     8161 tcacttgttt ggaagtcaag gcctgggatt cccccctgct gatgaatgac aggcggtgtt
     8221 gatggcaggt gtggcgttgt tgctgcaatg tgatgtatgg ttgcagatgg caggcttgat
     8281 ttgaggatat agtggtaatg gtcaccatga cgaacagtgt agccataggc atcctctgcc
     8341 acaatatcag ctggattgaa gacatagcca tctccagcat ggctgactgc tgctgttgag
     8401 ctagctttag cagcctgact aggggaaggc tgtgcttcct tgtaatcctt aggaatcagg
     8461 taagcccatt ttgtcccctt caaatctgag taaaagaaga aatgcttgtg atcgccatgc
     8521 ttcacaatga tacctgtatc tgttttgcgt tcaatttgcg attcgctggt caataaaaag
     8581 ccatcatcag ttgggacatc aatcccaggg acttggtgac gttctctttt tttcgcagtc
     8641 ttactgcttt tttgtttttt ctttttcgca gccttttggt gctttttagg ctcctgagaa
     8701 tgtccctttt gcgaatgcgt ttggcaggct gttaaggcaa ggttgcaggc taacagcagt
     8761 ccaacgaggg ataaaaatcg tttatgttgt ttcatggtta gttatcaact ccttccaaca
     8821 attaacttaa ccagttaatg ttattactgg ttaagtatat catttgacat ctcagaatac
     8881 aatagatttt ataaattttt taatgaaatt aatctaatga cctaagagct gtctggaaga
     8941 tgaaaggctt cttagctatt tcaaaggctt ggagcttcaa caggcgaatc agctattggt
     9001 ttttctagat ttacaagaga gctgctcttt tttgatgtag ctggtataaa atatggtaaa
     9061 atagggtcta tcaagagcct atctaccttt agactggctg agatttgtta ggcaatgcgt
     9121 tcttggtaag ggctgggctt atggacaata ggccttggtg ctatgtttgt ccttagtatg
     9181 aaacctctga gacggcagag caggatctgg ttgatttagg accgcattag cttatcttac
     9241 gataaaaaag aagcttgaaa ggaagggctg ccttgatttg gtagaggctc actggtttta
     9301 gggtttagac taagggcaag tgactactga tgatatggca gccagggtat cgttatgaag
     9361 gcatggcaag agctgacaat tacagtccat cgtgaggcag aggaagctgt ttccaatctg
     9421 ttgatagagg ctggctgtca aggagttgct atcaatgaca ctgcagacta tatcggtcaa
     9481 gaggaccgtt ttggggagct ttatccagct gttgagcagt cagaaatggt tactattaca
     9541 gcctattatc caagctcagc tgatattgat gacatcagac agactattaa tcagggcttg
     9601 aacaggctaa agcagtgtga tgtggagctt ggcgagctaa ttctgactaa tcaagaatta
     9661 gccgaagagg attgggcgga caactggaaa gcctattatg agtctgctcg tatcacgcat
     9721 gatttgacaa tagtccctag ctggacagat tatgaagcca cagcaggtga gaaggtcatt
     9781 aggcttgatc cgggtatggc atttggaaca ggcacacacc caacaactaa gctaagcctg
     9841 tttgccttgg agcaggtgct tcgtggtggc gagacagtta ttgatgtggg gacaggctca
     9901 ggtgtgctat caattgccag ctctctgctt ggcgccaaag aggtctttgc ctatgattta
     9961 gatgatgtgg cggtgcgtgt tgccaaagac aacattgccc tcaatcaagc cactgacaat
    10021 atccatgtag cagctggaga cctgctaaaa ggccttactc aagaggcaga cgttattgtc
    10081 gccaatatct tggcagatat tttggtgcat gtgacagcag atgcttaccg tcttatcaag
    10141 gctgagggct atctgatcat gtcagggatt atttcagaaa agctggatat ggtgaagcag
    10201 gctgctctta atgcgggctt tttgctagag actcacatgc ttcagggcga gtggaatgct
    10261 cttattttca aaaaaacaga tgatttatca ggagtgattg gtggctaatg cagcagtatt
    10321 ttattaaagg cagggcagaa aaaatcgttc agctgaccga taaggatacc attaagcata
    10381 tgtttcaagt gatgcgcttg acggacatgg aagagctggt gctagtcttt gatgatggca
    10441 ttaaacgctt ggcaagggtg tcagacagct cagcctatga ggtggagctt atcaaagagc
    10501 tggaagaaaa ccttgaaatg cctgttgagg tgactattgc ctcaggcttt cccaagggcg
    10561 ataagctaga tgttatcact caaaaggcga ctgagttagg ggcagcagct atttggggct
    10621 ttccagcaga ctggtcggtg gtcaagtggg atagcaagaa gctagctaaa aagcaagaaa
    10681 aattagctaa aattgctctt ggagcagcag agcaatccaa gcgtaatcgc gtaccggaga
    10741 ttcaactatt tgaccaaaag ggtgagctat taaagcagct taagcagttt gataagtgct
    10801 ttatcgctta tgaggaagca gctaaggcag gtgaaaggtc gacattggcg cgtgagcttg
    10861 cagatcttag cccaggtcaa aaagtcctct ttatctttgg accagagggt ggtatttctc
    10921 caaaagagct ggctagcttt aagcaagcag gtgctattac tgtgggactg ggtcctcgta
    10981 tcatgcggac agaaacagcg ccgctctatg ccctgagtgc tgtcagctat gctctggaaa
    11041 tgatacctca ttaatataga aagcaagcag tcatttaaga ttgcttgttt tttcttttgt
    11101 tttttattag ctgacaaggc ttggaaggag ccccttactc cttatgattg tgttgttttt
    11161 ttgcaggagc attgattgac atgttttcca agtttagcaa caaaaataaa acaattattt
    11221 aattaagtgt tgacttatca aagattaaat atataacaaa ataaagcgat tgcttaaata
    11281 aaaataagta ggtatgaaaa tgaaaaaggt aatcactaat aggctattca tggcaacgtt
    11341 tgtatctgat atgttatcga attttggaga tgtcctgtat tacttggcct tgatgaatat
    11401 ggttcttctt gtgccagaga ctaagcttgc gattgctttg gttactgtat cagaaagctt
    11461 tccctatttg accatggttt ttatgggcat gtggggagat aaaacaagaa ataaagtaga
    11521 ccgtatctta gcgacacagc tttttagggt agtcttatat atgattgttg cttacgctat
    11581 gggatctaag ccggctcttt ggattgttat cgttgctgtt ttggttaatg ttttgtcgga
    11641 tttatctggt cagtatgaga atgctcttta tatgccttta agcttacgta ttgtttctga
    11701 tgaggatcgt gaggccatgt atgcttttcg acaaggaaca agctcggttt tacggattat
    11761 ttttcaatcc agtggtgccc tgcttgttgg tatcatgact taccagcagc tagctttttt
    11821 caatgctggt acctttctcg tcagtgctgt tatcatgctt gtgcttcgac ctagcctgct
    11881 tagacttcta aagaaaagcc ctatttcctt tgctgaatca acgagtaccg ctaacccttt
    11941 aagacatttt gtttcagact tgtggaaagc attgaaggag gcttttattg ctgtagacaa
    12001 gattcccagc ttgaaggctt ctattttagc gatagctggt ttaaatgcta tttttgcagc
    12061 agaagatgcg cttattctct taacgataag agagcatgct gattttatga ttattaatcc
    12121 agcagttact ctagcagcat tttcaattag ttccttagct ggaatgatta gtggcagcat
    12181 tttgataaca ggggtgttta aggaggtatc atttaagctg ctattacgag ctgcagtcct
    12241 catgtcttta ctattgtttg tgggctatct ttgtcatgcg gttggttttg ttttgctgat
    12301 tcattttttg gcccttacca tatgtggtgt ctttaatccc aagatgaatg ctcttgtcgt
    12361 gcgttctctt cctgaaaacc gtttggcgac cgttggagcc ggtattgata gcttttgtac
    12421 tcttggtatg gttgtcagtc gttggacctt gtcagttctt gtaacggtct tatctgctgg
    12481 gacgatttcg ctgatcttta tcttgctatc attagctctt ttaggctata ctataagcat
    12541 aaagaaatac tagtaaagaa attgagcata cgatgaacat tatttattct gaaacagcta
    12601 gcgagctagt agagcagttc tattttcccc aatttgccgt cagcgtatcg gattgggaat
    12661 gggattttac gaataaagaa aggggtctct tgcgtgatgt ttggccgata ttagaggagc
    12721 tatttgattt gttctccccc tacaaggaaa aaatcgcctc ttattgcctc ttgagcggtt
    12781 ctggtagtat tttacatgct tgccttttag acatgcttaa gaaagggcta gctcctaaga
    12841 cggtaaaagc tgtttatgct tattgcctag agctatcaga ggatcaggtt cgtcagctct
    12901 tgattgatat gctaaataca gaggcagagc ctatggacaa ggcctctttt tgggagtgct
    12961 tggaaatgtc atctaagaag ccagaggata aatggcactt tagtcgcttt taccgtcacc
    13021 ccttagaatc aatgaaggag ctagtggagc tatcacgtga gcttatcttg ctttatcagc
    13081 cttatctaga aaaaggcagg gctgagcgtc aggcttatgc aaaaacgttt ttatcagagg
    13141 gctttttgga agggctcttc tcccgattta atgtagcctt tgatgagaat gagacgatct
    13201 accttcatat cgtgagtcct tggattattc gtttgtctat atctagtgat ataagccaaa
    13261 acgaaggaca gactcgttgg tcccttgtag cctccagccg tattgatcag cttatagaat
    13321 cgcgtagaga gatagatagc gacagctttg ccaatacctt gaaaatcctc agtgatgcca
    13381 cgcggtataa tgtttttgtt gccttaacaa agcctcatgc taaaagtaag gacattgcaa
    13441 aggatttagc gattaccggt gcagctgttt cctttcatac tcaaaagctg attaatgctc
    13501 agcttttggt cgtcaataga gatgataagg atatcaaata caatcccaat aaggctttac
    13561 tcaaagaagt gattgctaag ctggaaactg attttgcttt gggggactaa tcagtctgta
    13621 cgattgcttt actactaagc tttggctgct tttttacaac tgatgaaaca attgatgatt
    13681 tatcctagac ataaggatac tcgtcaaacg gattggtaga ggagggacat gtggttacga
    13741 taaaagatgt ggcaaggcta gcaggagttt cgccttcaac agcttcgcgt gccatcaatg
    13801 acagtgacat gattagtcag gcgacaaagg agcgtgtcaa aaaagccatg gaggccttgg
    13861 attattcgcc taattattcg gcgcaaaacc ttgttaagcg aaagtccaat actgtcggga
    13921 tcattttgcc ggtgcgtgag ggtcaagatt cactgggaaa taaccctttt ttcatgcaga
    13981 ttattcaagg aattgctgct gtttgtaccg atcagggcta catggtagcc cttgcgactg
    14041 gacgtagtga ggccgaattg ctaaaaaacg tgcaaaacat gatccgtagt ggcaatattg
    14101 gcaagctgat ttttctttat tccaaaacag atgatcaggt ttttgacttt gtcaaaaggc
    14161 aaagagtgga ttgtgttgtc gttgggcaat caacgacaaa ggatcctggc aatgctaaat
    14221 ttgtcaacaa caataaccat caagccggct atgatgcagc agcatttctc cttcaaaaag
    14281 gctatgaggc tattgtctat gcttatactg acatggccga attggtgcag gcagagcgtt
    14341 ataagggcta tgcagagctg atgacttcaa aggctctggc agctcaagcc ctttgtgtca
    14401 cgctaaagga cgataggaaa agtcaaaagc agctgttaga ccaattagcc aagcgctcta
    14461 aagttgcctt tgtagtctgt gatgatgtgc tagctattca tttgcagcgt ctcatcaagc
    14521 aagtagcagc tgacacccag ctagcaatcg ttagcttcaa taattctgtc ctagcggagc
    14581 ttgcgagtcc tgccttgacc tccattgcta tttttcccta tcagctggga gagcaagctg
    14641 ctgagctggt cttatcaagc gcagcgccat caccacagcc agtcttagtt cctcatcaga
    14701 tcattgaaag agagtctaca ccttttattg tttgatttac cgttaagcct attcctaagc
    14761 aaagcactga tagcttgctt aggaataagg ctttttattt aggaatttat tttgtttgct
    14821 aatagtatta aagagaagca acgtttactt tagcattttc attgaaatct tcttaagaaa
    14881 acgctttaca aaacaaaaaa aggttggtaa aataagctta tcaaaagcgc aaacgtttgc
    14941 gttgggcgtg cttattttaa aaaggaattg agagttcatc agcttttagc tggttattct
    15001 caattcctag tccaaaaaag gagaggtcga atgaaaacat cattcaaaca attttttagc
    15061 ttcgagtttt ggcaaaaatt cgggaagtgc ttgatggttg tcattgctgt tatgcctgct
    15121 gcaggtttaa tggtgagtat tggaaattct ctgcccatac ttaatcagga gtcgcagctt
    15181 ttagcgacgc ttggtaatgt cattgctcag gttggttggg cagttattgg taaccttcat
    15241 ttgctttttg cccttgctat tggtggcagc tgggctaagg agcgtgctgg cggtgccttt
    15301 gcttcagggc ttgcttttgt tttgattaac cgtattacag gggctatcta tggcgtttct
    15361 tcagccatgc tgactgatcc agaggccaag attaaaagtc ttttgggcac tgagatgatt
    15421 gtcaaggact actttacaag cgtcttagag tcacctgctc taaataccgg tgtctttgtt
    15481 gggattatcg ctggctttgt gggtgcaaca gcctataaca aatactacaa ttaccgtaag
    15541 ctgcctgatg tgcttgcttt ctttaatggg aaacgctttg ttccttttgt ggttatcctt
    15601 cgttcggctc ttgtggccct agtattagcc ttgatttggc cagttattca gtctggtatt
    15661 aatggctttg gcatgtggat tgcctcatct caggacacag ctccaatcct tgcgccattc
    15721 ttatatggaa cattggagcg tctcttgctg ccatttggcc ttcaccacat gctaacgatt
    15781 ccgatgaact atacagctct tgggggcacc tatgaggtca tgacaggagc agctgctgga
    15841 actaaggtat ttggtcaaga ccctctttgg ctagcctggg ttactgacct tgttaatctc
    15901 aagggctcta atgcgtcaac ctatcagcat ttgatggaga ctgttgttcc ggctcgtttt
    15961 aaggttgggc aaatgattgg tgcaacagga acgcttatgg gggttgccct agcaatgtac
    16021 cgtaatgttg atgcggacaa aaagcataaa tacaaaatga tgtttatctc ggcagcggca
    16081 gcggtatttt tgacaggggt cactgagcca ctggaataca tgtttatgtt tgctgcgatg
    16141 ccattatatc ttgtctatgc ccttgttcaa ggagcttcct ttgcaatggc tgatttggtc
    16201 aaccttcgtg tgcattcctt tggcaatatc gagctattga cccgcacgcc tatggcaatt
    16261 aaggctgggc ttggtatgga tttgattaat tttgtctggg tgtctattct gtttgctgtg
    16321 atcatgtatg ttattgctga ctttatgatt aaaaaaatga agctagcaac agcaggtcgc
    16381 ctaggaaatt acgatgctga tatgctagaa aatgatgata caaggccttt gtcacagcag
    16441 tctattgatg gtcagtcaca ggtcgtccaa atcattaatc tcctgggtgg acgtgagaat
    16501 atagctgatg tagatgcttg tatgactcgc ttgcgtgtaa cggtcaatga tccaagcaag
    16561 gttggcagtg aggagcattg gaagcaggca ggtgctatgg ggctgatcat caagggcagt
    16621 ggtgttcagg ctgtctatgg gccaaaggct gatattttga aatcagatat tcaagatcta
    16681 ctagactctg gtgcagtcat tccagagctg aagcctgctc agcttgctgc ctcatcatca
    16741 ggacagacag actttaaaaa cctgacagag actgttttaa cagtagcaga tggagaagtc
    16801 ttgccaatca cagcggtttc tgatcaggtc tttgcagcta aaatgatggg tgatggcttt
    16861 gctgttgagc cggcaaatgg cgctatctat gcgccggtaa caggtctggt aacccatgtc
    16921 tttccaacca agcatgcctt tggcttgctg acagatagcg gcctagaggt gctggttcac
    16981 gttggtcttg ataccgttga cttgaatggt gagcccttca ctgtcaaggt tagtgagggt
    17041 cagcgcgtat cggcaggaga tctcttggct gaggctgacc tagctgcgat tacagcagca
    17101 ggacgcaaga caacggttgt tgtcgccttt accaatacta caagcatcaa agctgttaac
    17161 cttgttgcgc tgggtcaaca aaaagcgaag accctcgttg cacaagtaga gctttaagaa
    17221 taaccaaaga gagtggtaga tagcagtatg tcagacctgc aggctgccac ttctcttgtc
    17281 gtataggaga agatatgacc aagctcttaa cccttaacac acattcttgg atggaagcca
    17341 atgccttaaa aaagctgttc gacttggcag agcatatttt ggctcagaac tatgacgtga
    17401 tttgcctaca agaaatcaat cagctgattg acagcgaggc agcattgtca ttatcaggct
    17461 accagccaat tgcagggacg cctgccattc atcaggacaa ctttgccctc ttgcttgtta
    17521 attacttaaa aaaacgtggt caaagctatt actggtcgtg ggcctacaat catattggct
    17581 atgatattta ccacgagggt gttgcgatct tatccaagca gccgatccaa gcctcagaca
    17641 ttttagtctc agcggtggct gatgagtatg attaccacac cagacgggct ttactggcca
    17701 aaacaaccat tgatagcagg gaggcagcag ttgtgagcct gcatttgtct tggtttgatc
    17761 agggctttgt cggagaatgg cagcgattag aggcagcctt gcagcagcta gcctgtcctg
    17821 tactattgct gggagatttt aacaatccaa gtggccaaga gggctatgag atgattctaa
    17881 aaagcccctt agatcttcag gatagtcatc aggctgcaga ctacgtcttt ggagaccata
    17941 gtattgttgc tgctattgat ggctgggagg ataacaagga ggcctttaag gtcgaccatg
    18001 tctttaccag taaggtcttt accattaaca gctcaaaggt gacctttgat ggtggtgaag
    18061 caccggttat cagcgaccat tatggcttag aggttgacct cgactggaag ctgtaataaa
    18121 aaagccagca ggacttgata gactgctgac actgtaagaa acagattgtt atcttagctc
    18181 ttagaagtaa gcttatcgca aggcttctaa gagccttttt gcatttatat ttcatgagca
    18241 tatgagaaag ttgcagacaa atgctggaca cataatcaga ctgtgggcta gttacatcgt
    18301 ctgctctgat ttgtgtcaga tagtgacgat ctgtgctgcc ttatgattgg ccagatattt
    18361 acctcatatc aatagcagaa agtcaagtct ccctcagctt atctcctagc ttacgattgc
    18421 tgatcatcag tcagtctagc tacaattacc tgtgccaagc gctcaatatc agcactggtc
    18481 ccgcgtagtt cgaaatctcc cagcattgga aagccaaagc gcttagcata ctgcttggct
    18541 gttagacaat actggtgatt gaagtttttg ttgccagagc cgataatccc tagacaacgc
    18601 ttggcattat catgcgccgc gataaagtct cccagcggat tggtcaagat ttcgacctcg
    18661 cctgagtcaa tcccgtttcc tccctcaaga taggtcggca aaatagcaac aaagctctcc
    18721 ttgactggaa aggtttcgtg atgaagctcc ttgatattga ttgctttagt ctgtatgtgg
    18781 tgcttttctg ccaggtattg cgacaagcgc ctcacaaagc tcagagtatt gccgctaagg
    18841 ctgataaaaa caagggttaa gtctgtcata aaagactcct ttagcaagat tagtttccta
    18901 accagcttag cacaataccc ctgaatacac aactcatatg acaatgctct gcacgacaaa
    18961 cgcgcgaaac agtcatttcc gaatgatagt atagacttaa gcagatacat tcaccgtttt
    19021 ttctatagta aaagctataa aaaataagat atcttcttga aatagctaaa cattgacata
    19081 cagaaagctt tattttcttg ctaaaaccct atcatgcgtc tgtcgtgcaa tgctctgaca
    19141 gctagcccac tagtcacatc atataaaaaa ggcttgatga caaggacttt aacgccaaat
    19201 catcaagtct ttttatggag agagcttagt agtagctgtt agtcggatca agaggccctt
    19261 gctgctaatg cttgcgattt tgataggtct ttgggctttc tccggtatgc tttttgaaaa
    19321 atttagaaaa atgtgaggga tcagtgaagc ccagcacgtc tgaaatgtga ttaatggcat
    19381 aagcagagcg cagcaatgtc ttagcctctt caattttcat attagaggtg tattgataga
    19441 tggttaagcc tgtatcacgc ttaaagatct gtctcagctt ggactcgctc atgttaaaat
    19501 gctgtgccag ctcagcagtt gtgatactct tatgcaggtt gacactgata tattggataa
    19561 tggcgttaac cgtaggagag acatgcttcc agcggttgtc ccgcagctca ctcacctttt
    19621 gggtgtaaaa gaccagtgag gcatcacgaa ttttgagcac atctggcatt gaggttgcca
    19681 gctcgctgtc tctcatgaac tcctctcgtg aatggtaggc atcagcaata tccataccag
    19741 attgaatggc aatctgggct agtcgatcaa aggcaatgat agaataattt ttttcagagc
    19801 gcagcgtatc accactcacc acagggataa aggtatttcg tagactgaag atgatttcct
    19861 tgagcttgtg cacatcaccc tcttgaacaa tgctagatag gtttttctca taattgtaga
    19921 gacaaacctt agattcctgc ttcttgacaa acatattggc cttttgcacc tcgatattgt
    19981 cggaaaaatc cctaatatag tgacgtaaag gaggtgataa caaatcctct atcttgccgg
    20041 aaaagaagta atggaccaca atcaagaggt cacgaatagc attcaaagga taaacaggta
    20101 aatgctttag cgcttggtaa agaatctctt cttcttcctt agtcaaatcc ttatcagcaa
    20161 cggccacctt aaaaaaggtc ttatccaaaa cattacagcg ccaagggcca attaaaatat
    20221 aatgatcctg ataacggtat attaaaaaaa gctcattata gcttccctga aagaaaagat
    20281 tggtcaattg ctccctatcc atttgcctaa gcactgcttg aaaacgataa taaaattcaa
    20341 aggtatcatc attccaaaag ctttctgtca cctgatggtc cttatcaaat actgtaattg
    20401 ataacttcaa gcaggcctgt agagatttta ctaacgacat agtatccatg ctaagcgtca
    20461 cccccttcat aatcctcgcg gtatcttatt ctatcttaaa atttaagaaa agcaaggata
    20521 tgcacttata atgaaaaaat agacataaaa aacaataata tacattattt gttattaaat
    20581 aaaaatgaca atgtactgca taaagaagtt cctgtcatta aaataaaagt gccatgagac
    20641 tataataata tggtaaaaca aaaaagtgtg cccataacgg gtagagagga attgacatat
    20701 gtttttgaga aataaaaagt aaaaatttag catcagaaaa ctaagtgccg gtgcagcatc
    20761 agtattagtt gcgacaagtg tgttgggagg agtaacggta ggatttacta gtagtatagt
    20821 ttctgctaaa gaagaagtta ccccaaagga tagatctaag tttggagcat tgattgttga
    20881 taagaaatta tatgaaaagt tgaaaggata tagtacttta gggaaaggtc cttcacaggt
    20941 gctaagtgat ctacgagaga ttctatcaga gtcggatccg gagacgatgt tagaattgct
    21001 taatagttta gataatgcac gtaatggtta tggtgaatac gtttggcaaa ataatttgtt
    21061 taatcattat actaaagaat ttggtagtct tcctgcagat agtggtgatt tttcacatcg
    21121 gtcatattcg tttacttccc tactgttgga agcagtcaag gaacgtgtta tgaatgaggc
    21181 taaatttaaa aatgaattaa ctaaaaaagt tgctgaatta gaacaaatta cagatagtga
    21241 acgaatcgaa agaaaagcaa aagaagaact tgaaggtaaa ctgagagatg tatcttctaa
    21301 tcttcaaata aaagaaaatg aactggttga ggctaaagaa attaataaga atcttgcaaa
    21361 gtcaatcgct aaaactttat caagatcaac caaagaaaaa gacaaattaa aggaagagct
    21421 tacaaaagaa aaaactaaag cagccaagat aactaaagaa cttatggata aattgactgc
    21481 ttcagaaaaa gataaaaatc gtgctattca gattacaaca gagttaacta ataagttaac
    21541 tgatgctgaa gcaagtcgtg ataaagcttt tgcggtatca acagaactag ctaataaatt
    21601 ggcagctaaa acagcagaag ctgaaaaatt gatgcaaaac gttggtagtc tagaccgctt
    21661 ggtagagtct gcaaaacgtg aaatggctga aaaattagca gaaattgatc aattaactgc
    21721 tgataaggct aaggctgatg cagagcttgc agctgcaaat gacaccattg catcacttca
    21781 aacagagctg gaaaaagcta agacagagct tgctgtttca gagcgcttga tcgaatcagg
    21841 taaacgtgaa attgctgagc tacaaaaaca aaaagatgct tctgataagg ctttagcaga
    21901 atcacaagct aatgtagcag agcttgaaaa acaaaaagca gcatcagatg ctaaggtagc
    21961 agagcttgaa aaagaagttg aagctgctaa agctgaggta gcagatctta aagcacaatt
    22021 agctaagaaa gaagaagagc ttgaagccgt taagaaagaa aaagaagcgc ttgaagctaa
    22081 gattgaagag ctcaaaaaag ctcatgctga ggagctttca aaacttaaag aaatgcttga
    22141 gaagaaagac catgcaaatg cagatcttca agcagaaatc aatcgcttga agcaagagct
    22201 agctgacagg attaagtcat tgtcacaagg tggtcgtgcg tcacaaacaa acccaggcac
    22261 tacaactgct aaagctggtc aattgccatc tactggtgag tctgctaacc cattcttcac
    22321 tattgcagct cttactgtca tcgctggtgc tggtatggct gtggtgtctc ctaaacgcaa
    22381 agaaaactaa gctatttcct ctttccccaa tggacaatag ccgaaataat agagcgacta
    22441 tcgttctaac acaaaagcaa cagcctcctg tctgttgctt tttgtgatat tagggctcat
    22501 cagcctaggc taatggtttt ctgcgcttta tctgcaagct ttgaggattc cttcttttgc
    22561 ttttacagtg aaagtgttaa aataggaaaa acaactagta attgaggaag taaatggtta
    22621 aagaaatcaa tttatcagga gaggaagttg tcgctcttgc tgccaagtac atgacagatg
    22681 gtgacgtcga gcttgtgcaa aaggcgcttg attatgcgac agccgcccat ttttaccagg
    22741 tgagaaagtc gggtgaacct tatattgtgc accctattca ggtagcagca atcctagcag
    22801 acctgcattt ggacgctgtg acagttgcct gtggcttttt gcatgatgtg gtagaggata
    22861 ctgatattac cctagaggac attgagtttg actttggtaa ggacgttcgt gacattgttg
    22921 atggggtcac aaagcttggt aaggtagaat acaagtctca cgaggagcag cttgctgaaa
    22981 accaccgcaa aatgctcatg gccatgtcaa aggacattcg tgtgattttg gtcaagctag
    23041 ccgaccgact gcacaatatg cgcaccctca agcacctgcg caaggacaag caggagcgga
    23101 tttctcgtga aaccatggaa atctatgccc cgctagccca tcgcttgggg atcagtcgga
    23161 tcaagtggga gctggaggac ttggcctttc gctacctcaa tgagatcgaa ttctacaaaa
    23221 tctctcatat gatgagagaa aagcggcggg agcgcgaagc cttggttgat gatattgtca
    23281 ctaagattaa agcctacacc accgatcagg ggctttatgg tgatgtctat ggccgtccca
    23341 agcacatcta ctcggtttac cggaaaatgc gtgacaagaa aaagcgcttt gatcagatat
    23401 ttgatttgat tgcgattcgc tgtgtcatgg agacacaaag tgacgtttac gcgatggtcg
    23461 gctacattca tgagctctgg cgtcccatgc ctggccgctt caaggattac attgcagcgc
    23521 ctaagaccaa tggctatcag tcgattcaca cgactgttta cgggccaaaa ggaccgattg
    23581 aaattcagat tcggaccaag gaaatgcatc aggtcgctga gtacggggta gcagcccact
    23641 gggcctacaa aaaaggtatt cgtggcaagg tcaatcaagt cgagcaaaag gttggtatga
    23701 attggattaa ggagcttgtc gagcttcagg ctgcctcaaa tggcgatgct aagggctttg
    23761 ttgactcggt gaaggaggac atcttttcag agcggatcta tgtgttcaca ccaacaggag
    23821 cagtgcagga attgcccaag gattcaggcc cgatagactt tgcctatgcc attcacactc
    23881 aggtcggtga gaaggcgaca ggagccaagg tcaatggccg catggtgccc ttgacagcca
    23941 agctaaaaac cggtgatgtg gtggaaattg tcaccaatcc gaattccttt ggccctagtc
    24001 gggactggat taagctcgtc aagaccaata aggctcgtaa caagattcgc caattcttta
    24061 aaaatcagga caaggagctg tcgatcaata aaggacgtga gcttctggtt agctattttc
    24121 aagagcaggg ctatgttgcc aacaagtacc ttgagcgtaa gcgtattgag gagattttac
    24181 caaaggtcag tgtcaaaagt gaggagtctc tctatgctgc tgttggcttt ggagatatta
    24241 gcccagtcag tgtctttaat aagttaactg aaaaggaaag gcgtgaggag gaacgtgcca
    24301 aggccaaggc cgaagctgag gagctggtta agggtggtga ggtcaagcat gaaaacaaag
    24361 agattcttaa ggttcgcagt gaaaatggcg tgattatcca aggagcgtct gggctcctca
    24421 tgcgtatcgc caaatgctgc aatcccgtac caggagatgc gattgaaggc tatattacca
    24481 agggccgcgg tattgctatt caccgcgcag actgtcataa tatcaagagt caggacggct
    24541 atcaggagcg tctcattgag gtggagtggg atctagagca ttccagcaag gactatcagg
    24601 ctgagattga tatttatggt ctcaatcgca taggcctact taatgatgtg ctgcaaattc
    24661 tatctaacgc caccaagagc atttcaactg tcaatgccca gccgaccaag gacatgaagt
    24721 ttgccaatat tcatgtgagc tttggcattc ccaacctagc ccagctgaca gctgttgttg
    24781 aaaaggtcaa ggcggttcca gatgtttaca gcgtcaaacg aaccaacggg taaaaaggag
    24841 accaaccatg aaaattgtga ttcagcgcgt caaggaagcc tcagtgtcga ttgatgggaa
    24901 aatagctggc gctattgatc aaggcttgct gctgcttgtt ggcataggtc cagatgacca
    24961 agcagaggat atagattatg cggtgcgtaa aatcagtcat atgcggattt tctcagaccc
    25021 cgagggcaag atgaacctat ccattcagga cattgagggc agtgtcttgt ctatctcgca
    25081 gtttacgcta tatgctgaca ccaaaaaggg caaccgacct gccttcaccg gggctgctaa
    25141 gcctgacagg gccagccagc tttataacag ctttaatgat catctggagg agctagtgcc
    25201 tgtgaagcga ggtgtctttg gtgcggacat gcaggtcagc ctgatcaatg atgggccggt
    25261 tacgattatc ctagatacga aacatcgata actgcccagc aatcgatcgt ttgcttagga
    25321 gagtcatata aaggaaaaac aaaaagacga gtgactttag aagcactcgt ctttgtcgtc
    25381 tatgctgtta cgttgaagct agctagggct attaatctta tttttgcagg tctttgtaga
    25441 ctgcaataaa ttctgtctca gaaattgggg ttaagcttcc ggtgaattgg taggtcgtcc
    25501 catttttagc ttggaaggta tcaagtaaac ctgtatgatg tttaaggtat ttgtcgatag
    25561 tctcagtggt aattgcttcg tgtgttttaa aggtgtattc gttaatcagc tgctgctgtt
    25621 tgtcctgttg gtaaatagta actggacgat aggttgtgct atagtcatcg ttaatatcct
    25681 tagaaataaa ataggtttct gtaactatgt cttgatgact agcataagtt aatggatcag
    25741 ttacatcata gcttggacta tatgcttgag ctatcctgtt agcgtctacg atatagttaa
    25801 agtcttcatc gcgatcagca tggtagacca tgcgttcact agctccactg taaatctcac
    25861 cgttatggct ttgatgagtt atatcaggat cctgcgtaac tgttgtactg attcgcttga
    25921 cgagctgata cccgtcttta aaggcttgag tggtttcaaa agccttttta gcagcttcaa
    25981 agagctcctc agaagagacc ctgctgccat agtatcttaa cccggtaagt ccttctttac
    26041 caaggctgtc agttacatca acattaacaa gctgcccatt gtcttttttg aggaatttaa
    26101 cgtgctgtgt cacagctacg gcatctgaat cttggattgg gtttcctgcc ttatctgtta
    26161 ccttaatgtc cttgagagct accttgctaa ttttttccac aaggacctga cccgtcaaga
    26221 tgtatgtttg gtctttttga tgatactgtc ctttgattgg tgtcgtaaaa tggtctgtgc
    26281 taagtatttc agctgtagaa gcttttgtta atttggcatt tttcaaacta atgaccttaa
    26341 agctttctgc tgaaggatct atgacgtctt gaactagctt tatcatctca tttgtggtgt
    26401 aggttttgcc atattctagt ctaatatcct gataatgtgg agatacgatg gtgtgattag
    26461 tgttatctac tccagtgata ttgaccatga ggtacagtcc tgtggtttct tgatagtctt
    26521 ttgaatggat tggcttagtg gtgtcctcgt atttatagtg atttgctacc ctactagagc
    26581 ttgaccatgc ccacccaact ttgtaatggt ttgctttaac ggcaggtgct cccaaggtca
    26641 tggtgaatag tccaatgact acagttccta tttctaaagg tgttttccca aggtgataca
    26701 gtctttttga agtcaacata tttcaaacct ccctaaatcc tgtcagtctc tatagttata
    26761 aaaatacaga gaatcgttag aagaattaat gtttcatgcc ggcaagatga gtgtaacaaa
    26821 agattggtgc cgatacaaga agatggagat tagagcatct ggtttcaatg agagttacat
    26881 aatagcagaa ggttttttca ctatgagagc taatcgtctt aaaatggtat aatagcaagt
    26941 gaataggcta tctaactggt ttaacagcca tttttagaga agcttaatag tattgctgat
    27001 aagtgactcg tatctccata ttacttttca aatgctatgt tagctatgat aagcgtgatc
    27061 aggctatcgg aaaatccagt gttcttaaag gctttgaagc tctggctttg aaccttagct
    27121 ctggtgtttc tatgaaaatg acttgggcct tgtaccagat aagaatgaag tcaaattgag
    27181 gttttttgac aaaatgtttg agtaaataca agctcataga agtctaatgt ataaaaatac
    27241 aattgtatca ccataatctg aatgaccaaa ccattaaaaa aataaaattt ttaaacattt
    27301 tggaaaacgc tttcaaaact aaaaagagct gtcctatagt cattgcttag cattaaagca
    27361 aggtgtgaaa tgttatcata tggagaaata ggctgtcttg tgctgtatct gtgccaaaaa
    27421 agaatgcttg tttttgtgat ataatgtgac taagaaacct gaaaggactg cttatggcat
    27481 taaaagacta ttttcctgat atgcaagagg gtgcatttcc tctagctgac caagattgga
    27541 ttagcgttga ggttgaggag cagtacctcc atttccccaa atccagcttg tcagagcgag
    27601 agcagctttt gcttggtttg gggcggcagc gcaaagagcc gtccaaggat cagaaatctc
    27661 cttggtatca ttatttgatt ctgggccaag gggagcagcc ggaggagttt cagggttgcc
    27721 agttcatcta tatcaaccat caatgtcctt tagcaggtga tttgattgag cttctaaagg
    27781 ggatcataga gggagttgag gctgttttgc ccattagcca gaccaggaca gcttttttgg
    27841 tctgtcacca tagccgttca gacctttttc agctcttagc agatttattg cccacgattg
    27901 agagcgattt tggtttggcc ttgatgattt ttatcggtaa tggctggtat caggtgtcag
    27961 gaaatgcctt gagagactat tttaaggaag aaaatgctgt gtttacagct tatcttgctg
    28021 agcactctgc cagtcgcttg ctgacctttt cagaggtcat gctctggtca ctcttagcta
    28081 acagtggttt gccagccttg tcaaagcatt ttagtcagct gcttttagcc aataaagagg
    28141 tcatggatct ggtgctcgcc atgtggcagg agcatggcaa cctggtacag acagcccagc
    28201 gcttgtatat tcatcgcaat tcgctgcaat ataagctgga taaggttgct caacagtcag
    28261 ggcttcattt aaagcagcta gatgacttag cctttgctta tctatttata ctgaagcatt
    28321 agatttgtgc agggtgccca aagacatttg ggcgttttgt ctatatgatg aaaacgctat
    28381 ctttgctata ataaaagcat caaataaaaa gtgtcagggg tgctagcatt gcagtcagct
    28441 agcagcctat ctgacccatt aggagtaacg catggttgaa ttaaacttaa agcacatcta
    28501 taagaaatac ccaaatacca cacactatgc tgttgaggat ttcgatttag acattaagga
    28561 caaggaattt atcgtttttg tagggccttc aggctgtggt aagtcaacaa cgcttcgcat
    28621 gattgctggg cttgaggata tttcagaggg tgaattgaaa attgacggtg aggttgtgaa
    28681 tgacaaatca ccaaaggacc gcgatatcgc gatggttttc caaaactatg ccctttaccc
    28741 gcatatgacc gtttatgaca acatggcctt tggtctcaag ctacgtaaat acaaaaaaga
    28801 tgacattgat cgtcgtgtca aggaagcagc agaaatcctt ggcttgacag aatttttaga
    28861 acgtaagcca gctgatctat caggtggtca gcgtcagcgt gtggctatgg gacgtgctat
    28921 cgtgcgtgat gccaaggtat tcctgatgga cgagcctttg tcaaaccttg atgctaagct
    28981 gcgggtgtca atgcgtgctg aaattgcgaa aattcaccgc cgtatcggct caacaacaat
    29041 ctacgtgacg cacgaccaga cagaagcgat gaccttggca gaccgtatcg ttatcatgag
    29101 tgccactaaa aaccctcaag gcaacggtac aatcggaaag attgagcagg ttggctcacc
    29161 acaggagctc tataacctac cggccaataa atttgttgca ggctttattg gaagccctgc
    29221 gatgaatttc tttgaggtgg ttgtcaagga cggtcagatc atcagtgagg acgggcttga
    29281 tattgctatt ccagaaggtc aggctaaaat gcttgaagca gctggctata agggcaagaa
    29341 ggtgattttt ggtatccgtc cagaggatat ctcaagcaac caaatcgtgc atgatactta
    29401 tccaaatgcc aatgtcacag cagaggtctt ggtttctgag ctacttggat ctgaaaccat
    29461 gctctatgtt aagcttggtc aaacagagtt tgcttctcga gttgatgcgc gtgacttcca
    29521 caatccaggt gaaaaggtta gcttgacctt caatgttgct aagggacatt tctttgatct
    29581 ggaaacagag caagctattc gctaataaca cctcctagaa taaaatcctc atcttgcttg
    29641 aggatttttt aacaaaagaa aatgcaagcg attgcgctat caaaaagaaa aagggattta
    29701 tcataaagac aacagatgtt ctgtagtgct aggcgatcat aatgatggca cgaaatagca
    29761 ggagactgtt tagtaataag gagatatgat ggaaaaacac tggtggcata aagcgacaat
    29821 ttatcaaatt tacccaaggt cctttatgga tacaagcggg aatggtattg gtgatttaaa
    29881 aggaatcaca ggtaagctgg attatctaca ggagctaggg atcacagcta tttggctgtc
    29941 tccagtttat caatcaccaa tggacgataa cggctatgat atttcagact atcaggccat
    30001 tgcagatatt tttggtgata tggctgatat ggacgagttg cttgatgagg ccaagcagcg
    30061 ggggatcaaa atcatcatgg atttggttgt caatcatacc tctgatgagc acgcttggtt
    30121 tgttgaggca agagaaaatc ctgacagtcc taaacgagat tattacattt ggcgtgatca
    30181 gcccaataat ctcacgtcaa tcttttctgg atctgcttgg gaatatgatg atgcctctgg
    30241 gcagtattat ctgcacctat ttagtaaaaa acagcccgac ttgaattggg aaaatgctga
    30301 attgcgtcaa agcatttatg acatgatgaa tttctggatt gataagggga ttggtggctt
    30361 tcgcatggac gtcattgacc tgattggtaa gattccggat tctgaaatta caggcaatgg
    30421 cccaaggctg catgagtacc tcaaggagat gaaccaggca agctttggca atcatgacct
    30481 gatgactgtt ggcgaaacat ggggcgctac accggaaatt gctcgtcagt attcacgtcc
    30541 tgaaaataag gagctgtcaa tggtctttca atttgagcat atcggcttgc agcataagcc
    30601 aaatgctcct aaatgggatt acgcagctga gttgaatgtt ccggctctca aggagatttt
    30661 tagcaagtgg cagacagagc taaagctagg tgaaggctgg aactcccttt tttggaacaa
    30721 tcatgacttg cctcgtgtcg tctccatctg gggaaatgat acagtgtata gggaaaaatc
    30781 tgccaaggct atggctattt tgctgcattt aatgcgtggg acaccttata tttatcaggg
    30841 tgaagagatt ggcatgacca attacccctt tgagcgcttg agtgatgtga atgatattga
    30901 atcactgaat tatgccaagg aggctatggc taatggcatg tcagaggagg ctgttcttga
    30961 tagtatttgc agggtgggtc gagacaatgc aagaacacca atgcaatgga gcagtcaaaa
    31021 gaacgccggc ttttcaactg ctgatcagac ctggctacct gtcaacccaa atcatcaaga
    31081 gattaatgtg gctagtgctc tagctgatcc tgattctgtt ttttacacct atcaaaagct
    31141 tattcagctg cgtcagacac aggattggtt ggtggaggca gattatcagc tgctacaaac
    31201 atcagataag gtttttgcct ataagcgtca gcttggtaga gagatttacc ttgttgttgt
    31261 caacctatct aatcaagagc agttttttga agaaagtctt cataaggccc aagtgattat
    31321 cagcaatacc gatgtgcagg cggttgtaga aagtcaacag ctggagcctt gggacgcctt
    31381 ttgtgtcaag cttgatgagg ccttgtaggc taattatgtg ctgctgtttt gtggtgcagt
    31441 cgtagcgatt ctttgagaat tttgacaaac tgttgtatga ttagtaatag tattagatgt
    31501 aaaaagggag gctgagatga cagttgaaga aaccatgacc tttgccaaaa gcattgcagc
    31561 atttagacag gtagagatta gtgaggtagt cactaggcta gcagcaggtg aggacatcac
    31621 cgtcttttta ggcagagcga cctgtcctta ttgtcgtcgc tttgcaccca agctagcaag
    31681 cgtagcaagg caggagcata aggatatttt ctttgtagat agtgaagatt caacagagct
    31741 tgcagacctg caggcctttc gtgagcgcta tgggcttgct actgtgcctg ccttgctcat
    31801 tagtcgtcat caggaggtca aggcagtctg tgattctagc ttgactgagg aagccatttt
    31861 ggctttccta gagcagtgac agacagctaa ttatctggtg caagtaatag aaatgtaatc
    31921 agtcatgtct tgctatgtga gtccaaatct gctatagtag gacatgactt ttagacgaaa
    31981 taaggagata ttatgggctt accaacaatt ttaatgtttg ttgtcatgat tggtttaatt
    32041 tggtttatgc agcgtcagca aaaaaagcag gcgcaggagc gccaaaatca gcttaatgcg
    32101 attgaaaaag gcgatgagat tgtgacgatt ggtggcatgt ttgcagtggt cgatgaggtt
    32161 gatttagcag caaagcgaat tgtcttagat gttgatggtg tctatctgcc atttgagcta
    32221 tcagcgatca agcgcgtggt cgaaaaagga agtgcagtga catcagctga tgtggatacg
    32281 acagagcctg cagttgatga cacagcggtt gaggcttcag acgaagctga atcagctatt
    32341 gagacaaatt aagaaaatga ggtctgaagc attagtgttt cagacttttt taggtgatga
    32401 tagcaggtag tcagacagaa ctgtcatgtg ctatggaaat atcgtctaca acgagaaaaa
    32461 gcgagccaaa ccgcatgaaa tatggtaaaa tatgaggtaa gtatgcttgt gaataaggaa
    32521 aaaacatgtt tggattaaaa gcgaagtcaa aaaaaatcgt tttggatagg attccaaagc
    32581 acattgggat catcatggat ggtaatggac gctgggcgaa aaaacgttta aagccgcgtg
    32641 tctttggaca taaggcgggt atggacgctt tgcaggaggt aacgattgca gcttcagatt
    32701 taggggttaa ggtgttaaca gtctatgcct tttcgacaga aaattggtca agaccacaag
    32761 atgaggtgag cttcattatg aacctgcctg ttgagttttt tgataagtat gtgcctgagc
    32821 tgcacaaaaa taatgtcaag gtgcagatga tcggtgagac caaccgccta cctaaggata
    32881 cactaaaggc cttggaagca gctattgcta agacaaggca aaatactggc ttgattctaa
    32941 actttgctct taattatggg ggtcgcgcgg aaatcaccaa tgctgtcggt ctcattgctc
    33001 aagatgtcct agacgccaag ctgaaccctg gtgacattac cgaggatttg attgccaact
    33061 atttgatgac ggatcatttg ccctatctct atcgcgatcc tgaccttatt atcagaacga
    33121 gcggtgaatt gcgcttgagt aattttatgc cttggcaatc agcctatagt gagctttact
    33181 ttacgccggt gctgtggcct gattttaaaa gagctgaact actaaaggcc atagaggatt
    33241 ataatcatcg tcatcgccgt ttcggtgcta tttaaggaga gagtatgaga gaacgtttca
    33301 tttggggtgg tgttgcagct gctgttttcc tacccttttt actcattggc agcttaccct
    33361 ttcaattgtt tgtaggtgtg cttgccatga ttggtgtatc agagctgcta agaatgaaga
    33421 ggcttgaggt cttttccttt gagggtgttt ttgccatgct agcagccttc gttttgacag
    33481 tgccgttgga tcattacctg acctttttgc cgatggacgc tagttttgct tgttacgggc
    33541 tgttggtgtt tttcctatta gcaggaacag tgattagcag cgattcttat ggctttgagg
    33601 atgctagctt tccgattgca gctagcttat atgttggcgt tggctttcat aatctggtta
    33661 atgcgcgaat gacagggata gacaaggttt ttctggctct ttttattgtc tgggcgactg
    33721 atattggagc ttacttgatt gggcgccgat ttggtaagcg aaagctcttg cccaaaatat
    33781 cacccaacaa aacaattgag ggcagccttg gtggcatagt cagtgcggtg cttgtttcct
    33841 ttgtgtttat gctctttgat aaggctgttt atgctcctca tcattttggg acaatgctga
    33901 tattggtagc tcttttttct atttttgctc agtttggaga tttggttgaa agtgctgtca
    33961 aaagacattt cggagttaag gactcaggca aattgattcc aggccatggt ggtattttag
    34021 atcgttttga ttcgatgatc tttgtttttc ccattatgca tctatttggg ttattttaaa
    34081 gctcattatc aatagactga aaggaaatct atgttaggaa taattacctt tattattatt
    34141 tttggtattc ttgtgattgt ccatgagttt ggccatttct attttgctaa acgatctggt
    34201 attttagtca gagagtttgc tattggcatg ggaccaaaac tcttttcgca tgttgatcag
    34261 caaggaacgc tttacacgat ccggctatta ccgcttggtg gctatgtgcg aatggcaggc
    34321 tggggtgatg acacaactga gataaaaaca ggaacgcctg ctagcttgac gctcaatgac
    34381 caaggtctgg tcaagcggat taatctatct cagggcaagc ttgatccgac tagcctgcct
    34441 atgaatgtga ctgcttatga cttagaagat aagttgacga ttacagggct ggttcttgat
    34501 gagaccaaga cctattcggt agatcatgat gctaccattg tcgaggagga tggtacagag
    34561 atccggattg caccgcttga tgttcagtat caaaacgcaa gcattggcgg tcgtttgatc
    34621 accaattttg caggacctat gaataatttt attctaggta ttgttgtctt tattttgttt
    34681 gcctttgttc aaggtggtgt ggctgattat catagcaacc atattcgtgt ggtggaaaat
    34741 ggcgcagcag ccaaggctgg tattagagac aatgatcaga ttttagagat taatcatcaa
    34801 aagattaatg actggtatga gttgacgcag gccgttactg attcagcagc agatgttaag
    34861 gctaagggca agctagagat tacctatcag acaggtgatc aggttaagac tatagcactg
    34921 aagcctgaaa aaaaaggcga tcagtacctt attggtgtcc agtacccact aaaaacaagt
    34981 ctgacagaca agctaatagg tggctttgag atggctggta atggtgctct agtgattgtc
    35041 actgctctaa agagtttgat tacctccttt agcctagata aattaggtgg gccagttgcc
    35101 atgtatcaga tgtccaatca ggcagcaaag aatggtttag agtctgtctt gtccttgatg
    35161 gcaatgctct ctatcaattt agggattttt aatttgattc cgattcccgc actagatggt
    35221 ggtaagatcc tgatgaatgt gattgaagca cttcgtcgta agccattaaa gcaagagaca
    35281 gagacttata ttacccttgc aggtgttgcg attatggtgg tactcatgat tgcagtgacc
    35341 tggaacgata ttatgcgagc ctttttccaa ggctgatggt ctctctcatt taaaggagag
    35401 cctaaaaggc ttaatgtaac agcaataaca agagatatag tgtcattatt gtggttctaa
    35461 gaccttgcaa atgcagcaaa agcttagcca atatagctca ttttgtctct tttttagaaa
    35521 tgaattctca acgaaaggaa agagagctgt tgaccaagct gggctaaggc ctacagctga
    35581 aatcaaaatg ctagacctgc tattagtcta agggcgtttt gagctgctct ctatagctta
    35641 ttttaatgaa acaaagtaaa atgcttatcc caaccctgcg cgaaatgcca agtgacgctc
    35701 aggtaatcag tcatgccctc atggtgcgtg cgggctatgt ccgtcaggta tctgccggta
    35761 tttatgccta tttgccatta gcaaatcgaa ccattgaaaa attcaagacg attatgcggc
    35821 aggaatttga caaaattggt gctgttgaaa tgctagcacc tgccctttta acagctgacc
    35881 tctggcgtga atcaggccgc tatgagactt acggtgagga cctttacaag ctaaaaaatc
    35941 gcgataaatc agactttatc ttaggaccga cacacgaaga aacctttacc acgctagtac
    36001 gtgatgcggt taaatcctat aagcagctgc cgctcaatct gtatcagatt caatccaaat
    36061 atcgtgatga aaagcgtcct cgtaacggtc tgcttcgtac gcgtgaattt atcatgaagg
    36121 acggctatag ctttcatcaa agctatgatg atttagatgt cacctatgac gcctatcgtc
    36181 aggcttatga ggctattttt accagagcag gcttggattt caaaggaatt atcggtgatg
    36241 gtggtgctat gggtggtaag gattcgcagg aatttatggc tatcacaccg gaccgtacta
    36301 atttagaccg ctggctggtc ttagacaagt ctattccgtc attggctgac attccagagg
    36361 aggtcttgga agagattaag gccgagctgg cttcatggct ggtttcagga gaggacacca
    36421 ttgcttattc aagtgaatca agctatgcag ctaaccttga gatggcaacc agtgagtaca
    36481 agccctcatc aaaggtaaca gccttagatg atctcatcga gattgagaca ccaaattgta
    36541 aaactattga tgaggtagcg gcctttcttg acattactga gcatcaggtc atcaaaaccc
    36601 tgctctttat ggcggaccat gagcctgtac ttgctctatt ggttggaaat gaccagatca
    36661 atgctgtcaa attgaaaaac cacctcggtg cagacttctt agagccagct agcgaggagg
    36721 aggcacatac gattctagga gcaggctttg gctcacttgg tccagttcat ttgacagatg
    36781 gtatccgtat tgtggctgat cgtaaggtcc aagaccttgc taatgctgta gctggagcca
    36841 acaaagatgg ttatcacctg actggtgtca atccaaatcg tgatttccaa gcagagtatg
    36901 ctgatattcg tgaggtaaaa gagggagaga cctctccaga tggacatggg gtgctccagt
    36961 ttgctagagg tattgaaatt ggtcatatct ttaagctggg gacccgctat tctgatagca
    37021 tggcggctaa tatccttgat gagaatggca gagctgttcc aattgtcatg ggctgctatg
    37081 gtattggcgt cagtcgtatc ttgtcagcgg tgattgagca gcatgctcgt ctctttgtca
    37141 gcaagacgcc aaagggtgat taccgctatg cttggggcat taatttccct aaagagctag
    37201 ctccgtttga tgtgcatttg attaccgtta atgtcaagga ccaggaggcg caggacctga
    37261 cagaaaaggt agaggctagt ctgatggcca agggctatga tgtcctcact gatgaccgca
    37321 atgagcgcgt cggctctaag ttctctgata gtgatttgat cgggcttccg attcgtgtga
    37381 cgattggtaa aaaagcagcc gagggcattg ttgagatcaa aatcaaagca acaggtgaca
    37441 gcattgaggt gcacgctgat agcttgattg aaacccttga tattctcacc aaggacaatt
    37501 aatgatatga ggtcaacgat tgttgatctc tttttgtatg ctataatgaa agcatgacaa
    37561 ttgaggaatt acagcagctg gtgctagcag atcatgagct aatgactatt ctaagcatta
    37621 tagagacctt gtctttaaag gattgttggc tggcagcagg tgcagtgcga aataccatct
    37681 ggaatcatgt ggcttatggg acaggctttg attcgctgac agatgtagat gtggtctttt
    37741 ttgaccctga gatctcctac caagatgggc agctgctaga agaacagctt aagtgtgctt
    37801 atcccatgta ccaatgggag cttcgcaatc aagtgtatat gcaaaagcat agtcccaaga
    37861 cgcctcccta tcaatctagt caagatgcta ttgcaaaata cccagaacgc tgtacggcga
    37921 ttgctgtcag attggtgaga ggacaggtag aggtttttgc tccttatggc ttagcagaca
    37981 ttagtcactt tgtctgtcgg ccaacaccgc attttttaga ggattcagag cgtatggact
    38041 gctataggca gcgcctagca aagaaggact ggcacaagaa atggccacag ctgacctacc
    38101 acaactgcta agtcagagga aacaaagcag gctaggagct ccgtacagcc aagcaattag
    38161 tccgctccca ggcccgtcag ctacagctct cacctagtca aaacaagcac atgaacagat
    38221 cattggcaga tagccttgcc tttgcagata ttgtcacatc ctatttagct gtaccatgtg
    38281 tcttatgata ggcgtgatag tgctgtcaga agcgccagct gagccagaaa aagcgttaag
    38341 cctacagcaa tggtttttta acctttggcg tgtcgtctta taggagaggt cgaaaatgat
    38401 cactatttat gataaaatag accctaagaa aatcaggaga aagctatgtc agatttattc
    38461 ggtaaattga tggaacaaat tgaaatgcca cttgagataa gacaatcaag tgccttttcg
    38521 tctgctgata ttatcgaggt caaggtgcat tcagtgtctc gtctgtggga atttcatttt
    38581 tcctttgcag aggttctccc gatagagagc tatcgagagc tgtcagatag gcttgtgaga
    38641 acctttgagg cagcagatat taaggtaaca tttgacatca aggcagagac aattaattat
    38701 tcggatcagc tgctgcaagc ctactatcaa gaagcatttg agcatgagcc ctgtaatggg
    38761 gctagcttca agtcatcttt ttctagactt caggtcaggt atgaccatca tcagctgatc
    38821 attatggcac ctgactttgt gaataatgat cactttagga aaaatcattt acccaatctg
    38881 gcagctcagt ttgagcgctt tggctttggg aggctagcga ttgatatggt gtctgatcag
    38941 gagatgacag accatttgac aaaggatttt gagatcaacc gtcaggctct ggtggaaaag
    39001 gctgtacagg ataatatcgc agcacagcaa tcattggagg ccatgcagcc accagctgag
    39061 gaggcagcac caagcccaag ccttgactat agagagcgta tggctcagcg ccaagcaagc
    39121 tttgataagg cggtcattac accaatgatt gaggtggata cagaagaaaa tcgcattgtt
    39181 tttgaaggaa tggtctttga tgtggagcgc aagacgacaa gaacaggccg ccatatcatc
    39241 aacttcaaga tgacagatta cacctcctcc tttgccatgc aaaaatgggc caaagatgac
    39301 gatgagctca gaaaatttga tctgattgcg aagggagctt ggctgcgcgt tcagggaaat
    39361 atcgaaaaca accccttcac caagagccta accatgaatg tgcagcaggt taaggcgatt
    39421 gttcaccatg agcgtaagga tctcatgcca gaagggcaaa agcgtgttga atttcatgca
    39481 cacactaata tgtccacaat ggacgctcta ccgacggtag aagacctgat tgatacagca
    39541 gccaggtggg gacatcaggc agtagcgatt actgaccacg ctaatgttca gagctttccg
    39601 catggctatc atagagcacg caaggcagga atcaaggcaa tctttggctt agaggccaat
    39661 attgttgagg ataaggtacc tatttccttc aatcctgtcg ctatggacct gcatgaagct
    39721 acctatgttg tctttgacgt ggagaccacc ggcctttctg ccatgaacaa tgatttgatt
    39781 cagatagcag cttccaaaat gttcaaggga aatatcattg agcagtttga tgagtttatc
    39841 aatccaggcc accccttatc tgcttttaca acagaattga cagggattac agataatcat
    39901 ttggtaggag ctaagcctat acagcaggtg ctagaggcat ttcaggcctt ttgccagggc
    39961 actatcctag ttgcccacaa tgctagcttt gacgtgggct ttatgaatgc caactacgat
    40021 cggtatggtc tagcaaaaat cagccagccg gttattgata ccctagagct tgctagaaac
    40081 ctgtaccctg agtataagcg gcatggttta ggccctttaa ccaaacgctt tcaggttagt
    40141 cttgagcacc atcacatggc caattacgat gctgaagcaa cagggcgttt gctctttatc
    40201 ttcctaaagg aagctagaga aaagcatggt attacaaacc tgcttcagct caatacagac
    40261 ttagtggcag aggattccta taagaaggct cggatcaagc acgctacgat ctatgttcaa
    40321 aatcagctag gcctcaaaaa catgtttaag ctggttagcc tttcaaatgt gaaatatttt
    40381 gaaggggtgc ctagaattcc aagaaccgtc cttgatcagc atcgtgaagg cttgctgctt
    40441 gggacagcct gctcagacgg cgaggtcttt gacgctgttt tgacccaagg aattgacgct
    40501 gctgttgatc tggcaaaata ctacgatttt atcgaaatca tgccgcctgc aatctaccag
    40561 cccttggtag tccgagagct aattaaggat caagcaggag ttgagcagat tattcgcgat
    40621 ttgattgagg tcggccgcag agctgaaaag cctgtcctag ctactggaaa cgtgcactac
    40681 attgagccag agggcgccat ctatcgtgac attatcgttc gtagtctagg gcaaggtgcc
    40741 ctgattaacc gtactattgg ccgcggagag gctgccaagc ctgtcccgct accagaggct
    40801 cattttagaa caaccaatga aatgcttgat gattttgcct ttttaggtca ggacttagcc
    40861 tatgaggttg ttgtgcaaaa tactcaagcc cttgctgatc gaattgaaga ggtagaggtt
    40921 gttaagggtg atctgtatac cccatatatt gataaggcag aagaaaccgt tgctgagctg
    40981 acttatcaaa aggcctttgc tatctatggc aacccacttc cagatatcat tgatctgcgc
    41041 attgaaaagg agctaacgtc cattttggga aacggctttg cggtgattta cctagcctca
    41101 caaatgctgg ttaatcgctc taatgagcgt ggttatctgg taggctcacg tggctctgtt
    41161 ggttcaagct ttgttgcgac catgattggt atcacagagg tcaatccaat gccgcctcat
    41221 tatgtctgcc caagctgtca gcactcagag tttatcacag atggatcggt cggatctggc
    41281 tacgatttgc caaacaaggc ctgtcctaga tgtgggacgc tgtacaaaaa ggacggacag
    41341 gatattcctt ttgaaacctt ccttggcttt gatggtgata aggttccaga tattgatttg
    41401 aacttctcag gagatgatca gcccaatgcc cacttggacg ttcgtgatat cttcggagaa
    41461 gaatacgcct ttcgtgcagg tactgttggt actgttgctg aaaaaacagc ctatggcttt
    41521 gtcaagggct atgagcgaga ttatggcaag ttttacccag atgcagaggt tgatcgtcta
    41581 gctgctggtg cggctggtgt caagcgaacc actggtcagc atcctggtgg gatcgttgtt
    41641 atccctaatt atatggacgt ttatgatttt acacctgtgc agtttccggc agatgatgtg
    41701 acagcctcat ggcaaacgac ccactttaat ttccatgata ttgatgaaaa tgtcctaaag
    41761 ctcgatgtgc tcggtcatga tgatcccacc atgattcgta agctgcagga tttatcaggt
    41821 attgatccga ttactattcc agcagatgat cctgacgtga tggcactttt ttctggaaca
    41881 gaggtgctcg gagtgactcc tgaacaaatt ggaacaccaa caggtatgct tgggattcca
    41941 gagtttggaa cgaactttgt tcgtggcatg gtgaatgaga cccacccaac gacctttgca
    42001 gaattgctgc agctatcagg tctatcgcat ggaacggacg tctggctggg taatgctcag
    42061 gatctgatca aagaaggcat tgccacccta aaaacagtta tcggttgtcg agatgacatc
    42121 atggtttacc tcatgcatgc tggtctagag cctaagatgg cctttaccat catggagcgt
    42181 gtgcgtaagg ggctctggct aaagatttcc gaggaggagc gcagctccta tatcaaggcc
    42241 atgcggcaaa acaacgtccc agactggtac atcgaatcct gtggtaaaat caagtacatg
    42301 ttccccaagg ctcacgctgc cgcctatgtt ttgatggcat tgcgagtggc ttatttcaag
    42361 gttcatcacc ccatcatgta ttactgtgct tatttctcta ttcgtgccaa ggcctttgag
    42421 ctcaaaacca tgagtggtgg gctagctgct gtcaaggctc gcatggagga catcagcaac
    42481 aagcgcaagc gcaatgaagc ctcaaacgtt gaaaatgacc tgtttaccac tttagaaatt
    42541 gtcaatgaaa tgcttgagag agggtttaag tttggcaagc tagaccttta caagagcgag
    42601 gcaactgagt ttcaaattga aggggatacc ctaattccac cttttattgc cttagaaggc
    42661 ttgggagaaa acgttgctag acaaatcgtc aaggctcgcc aagatggtga atttctatca
    42721 aaaatggaat tacgcaagcg tggtggtgct tctgccactc tagttgataa gatggacgag
    42781 ctgggcattt taggaaatat gccagatgac aatcagctga gtctatttga tgactttttc
    42841 taagattgca cagccctaat attgtctatg ttagcttgtc atacagtgaa gagcagggca
    42901 ggaaggcttc ctgtcctctt tttgtcaata ctaaaggaaa gcccaaaaaa gaacgaggaa
    42961 aagcatgaat gaattagaca aaaatcctgc cttaaaggca atggttgttt ttagaaaagc
    43021 acagcgtacc ttagatgctc aaagctccgc cttttttcaa aaggccaatc tgactcctac
    43081 ccaatttagc gtcttagagg tgctttattc caaaggaagc atgagaatta acaagctcat
    43141 cggttctctc ttggcaacct ctggcaatat gaccgtagtg ctgaaaaata tggagagaaa
    43201 tggctggatc agccgctgcc aagatgctaa agataagcgt gcctgcttgg tacagctaac
    43261 gccagagggc aaagccttga ttgagactat cctacctgag catatcaaac gtgttgaagc
    43321 ccttttttca gtgctgacag agactgagca aaaacaattg attacgcttt taaagaaatt
    43381 taaagagctc taagcaaatg gctttacaga atctcctaag taggatataa tcactacata
    43441 gtataaaaat gcactaacta gttataataa gtcatcaagg cagttgatgg ctagttatca
    43501 gatcatcaaa gggagacaaa gcatgaaaca gattttaatc atcaacggtt cattacgtac
    43561 aggatcgttt aatcaccagc ttgctcaagc agctgagcag ctacttgaag gcgaggcagc
    43621 tgtatcttac ttagactggg ggcaggtgcc tatctttagt caggatttag aagcaagtac
    43681 ccctgagtca gtggcaagcg tacgtgaagc tattcaagca gcagacgcta tctggatttt
    43741 ttcacctgtc tataattttg caatcccagg ctctatcaaa aacctattag actgggtatc
    43801 acgcgccctt gatctgtcag acccatcagg accatcagca atcaatggta aggtagttac
    43861 cgtatcatct gttgctaatg gcgggcacga gcagctattt gcgcaatacc aggacctgct
    43921 gccctttatc cgtacgacag tagttggtaa ctttaccaaa gccgctgtca atccagaagc
    43981 atgggcgaca ggtgttcttg atatttctga ggaaacaagg caaagcctgg ctgcacaggc
    44041 agaagccctc cttgaagcca ttaattaaaa tgccctacca ctaaaaagat catcagctgt
    44101 atctcatctt cagaagcagc ttgacataca aaagagcttc aaaccaggat tggtttgaag
    44161 ctctttttga aagattttgt tctataatag tggcttactc tagaattagc ataccctctt
    44221 tagcctcaaa ggggtttttc gcattaatac ggtcataaaa taagacaccg ttaatgtgat
    44281 caatctcatg ctggactacg atagcattgt agccctttag cttgatgcgg tgtttttcgt
    44341 tgtgtttatc gtaatattcc actgtcacac gcgcatgacg gacgacatag ccttccacca
    44401 cacgatcaac agacaaacac ccctcaccgt cagcaagagc agcgtcttga acagaatgag
    44461 acacaatttt aggattatag agcacttcct ccatgctgta agcctcctta ggtggattgc
    44521 cctcgctgtc ttcaggattt ggaaccagaa cagcgatgat acgctttgac acatcaatct
    44581 gaggtgctgc tagaccaact cctgctcgaa gccctaattt ttctcccatg acagggtctt
    44641 gagaatgctt taaaaattgc atcatttttt cacctaaaat gatgtcatca tcactaagag
    44701 gaaactcgac ctccttagcc acagcacgaa gcgtaggatt gccttcgcgg ataatatcat
    44761 tcatatcaat gagatgctgt gctttaatta atttatcttg tgcagacatt ttgcctccct
    44821 ttttttatat ttgataatgg ctttactata tcacaaattc cttattttta aaagataagg
    44881 caggccagtg atgacgatat tagctaactc tatcagatat attaaattat tcaaa
//
LOCUS       DARYSY010000014        44495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYSY010000014 DARYSY010000000
VERSION     DARYSY010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44495
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            254..327
                     /locus_tag="TVR04_000646"
     tRNA            254..327
                     /locus_tag="TVR04_000646"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:288..290,aa:Arg,seq:acg)
     gene            416..901
                     /locus_tag="TVR04_000647"
     CDS             416..901
                     /locus_tag="TVR04_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1269355.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTESELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(1347..2711)
                     /locus_tag="TVR04_000648"
     CDS             complement(1347..2711)
                     /locus_tag="TVR04_000648"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1269356.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLAASYFHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            2898..3647
                     /gene="truA"
                     /locus_tag="TVR04_000649"
     CDS             2898..3647
                     /gene="truA"
                     /locus_tag="TVR04_000649"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1269357.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            3637..4386
                     /locus_tag="TVR04_000650"
     CDS             3637..4386
                     /locus_tag="TVR04_000650"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1269358.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLARQNNGAGCSFAAAIAAYL
                     ARGHSPFRAVEQAKDLVFAAIQQSNDYGVVL"
     gene            4392..4865
                     /locus_tag="TVR04_000651"
     CDS             4392..4865
                     /locus_tag="TVR04_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1269359.1"
                     /translation="MKRTRELALVSILTALTVVLGRFVSIATPTGFLTLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLSGRYRFFGVGLAS
                     VVMVGLYFLAAIPMYGMGAAISGISGNVAQNILGIGVGYLLYLGVKKQLVKVSDD"
     gene            4878..5438
                     /locus_tag="TVR04_000652"
     CDS             4878..5438
                     /locus_tag="TVR04_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1269360.1"
                     /translation="MDLKVLREEARSILIDVVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKVVLEELSSRGIHLAVQGCEHINRALVLEESVAEEYQLELVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(5531..6370)
                     /locus_tag="TVR04_000653"
     CDS             complement(5531..6370)
                     /locus_tag="TVR04_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1269361.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTSL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVLYFLLIYWILSVLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTIAIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNNREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYHSFYKLYQEALLKEGIKLPTAPAIS
                     PLA"
     gene            6822..8237
                     /locus_tag="TVR04_000654"
     CDS             6822..8237
                     /locus_tag="TVR04_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family protein"
                     /protein_id="HEL1269362.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLTPLTSASLASAQEVQSA
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIKGDGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAKEADKYGISIIVDAVLNHTTSEISAVSPNITA
                     LGNWTHGNDKIENFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEYGYGSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYG
                     KLIRKALGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLG
                     WGIIAARNEGAPLFFSRPRGGGGQNGRFPGKSQIGDAGSDLFKDPTIVAINQFRNRMN
                     GQSEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKKFSSTTTLDDGDYKDAVTGTVYH
                     VSNHNITGHLAKKSVAVLLPA"
     gene            8570..9853
                     /locus_tag="TVR04_000655"
     CDS             8570..9853
                     /locus_tag="TVR04_000655"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1269363.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFNQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKGQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEDAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVTTVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            10120..10686
                     /locus_tag="TVR04_000656"
     CDS             10120..10686
                     /locus_tag="TVR04_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1269364.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            10960..12573
                     /locus_tag="TVR04_000657"
     CDS             10960..12573
                     /locus_tag="TVR04_000657"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1269365.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDKVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKELLGAADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKTGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            12932..13858
                     /locus_tag="TVR04_000658"
     CDS             12932..13858
                     /locus_tag="TVR04_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1269366.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPGNPLYPAELAFDSLVREKRSIVNRGHQQTAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKESQI
                     SLFGLSMGAATVMMASGEQLPSQVVNIIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            13912..13997
                     /locus_tag="TVR04_000659"
     tRNA            13912..13997
                     /locus_tag="TVR04_000659"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13946..13948,aa:Leu,seq:aag)
     gene            14198..15079
                     /locus_tag="TVR04_000660"
     CDS             14198..15079
                     /locus_tag="TVR04_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1269367.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            15669..16034
                     /locus_tag="TVR04_000661"
     CDS             15669..16034
                     /locus_tag="TVR04_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269368.1"
                     /translation="MTALSISKRSFLMSLGLLCVCIGLAVGTSHTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIEKIETSRLYRFIKNNYIDTINSHVFLYKLLYLEEHI
                     DILVARAKAEAESGIILDD"
     gene            16517..16705
                     /locus_tag="TVR04_000662"
     CDS             16517..16705
                     /locus_tag="TVR04_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1269369.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            16858..17223
                     /locus_tag="TVR04_000663"
     CDS             16858..17223
                     /locus_tag="TVR04_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1269370.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            17223..18887
                     /locus_tag="TVR04_000664"
     CDS             17223..18887
                     /locus_tag="TVR04_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1269371.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            19151..20041
                     /locus_tag="TVR04_000665"
     CDS             19151..20041
                     /locus_tag="TVR04_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1269372.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPNGVDDIRTQVLSALKTR"
     gene            complement(20565..20681)
                     /locus_tag="TVR04_000666"
     CDS             complement(20565..20681)
                     /locus_tag="TVR04_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1269373.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(21009..21749)
                     /locus_tag="TVR04_000667"
     CDS             complement(21009..21749)
                     /locus_tag="TVR04_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1269374.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            complement(21742..23310)
                     /locus_tag="TVR04_000668"
     CDS             complement(21742..23310)
                     /locus_tag="TVR04_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1269375.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            23626..24465
                     /locus_tag="TVR04_000669"
     CDS             23626..24465
                     /locus_tag="TVR04_000669"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1269376.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSLFK
                     SLF"
     gene            24585..25349
                     /gene="mecA"
                     /locus_tag="TVR04_000670"
     CDS             24585..25349
                     /gene="mecA"
                     /locus_tag="TVR04_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1269377.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVAATLAEQADNKEAAELEEPTEPLDYV
                     HYVLDFASVRDAVCFAKAIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            25356..26513
                     /locus_tag="TVR04_000671"
     CDS             25356..26513
                     /locus_tag="TVR04_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1269378.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTVTGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGI
                     LLMLGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            26634..27404
                     /gene="sufC"
                     /locus_tag="TVR04_000672"
     CDS             26634..27404
                     /gene="sufC"
                     /locus_tag="TVR04_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1269379.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDKDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAEELGIDYKEEV"
     gene            27496..28758
                     /gene="sufD"
                     /locus_tag="TVR04_000673"
     CDS             27496..28758
                     /gene="sufD"
                     /locus_tag="TVR04_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1269380.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTTLGTVPDFMAFGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALEEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDS
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDRAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIITALDDKLARR"
     gene            28785..30011
                     /locus_tag="TVR04_000674"
     CDS             28785..30011
                     /locus_tag="TVR04_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1269381.1"
                     /translation="MFDPNQIKADFKLLDQCVNDEALVYLDNAATTQKPQAVLETLQA
                     YYQKDNANVHRGVHTLSERATRQYEASRQKVADFIGAKSSKEVIFTRGTTTSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSIAHVSNVLGCVNPIQEIARLAHAQGAYLVVDAAQSVPHMTVDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPERADERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            29998..30435
                     /locus_tag="TVR04_000675"
     CDS             29998..30435
                     /locus_tag="TVR04_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1269382.1"
                     /translation="MALSKLNSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTVKFAGDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCSTLAWHALKQAIEKSEEL"
     gene            30474..31892
                     /gene="sufB"
                     /locus_tag="TVR04_000676"
     CDS             30474..31892
                     /gene="sufB"
                     /locus_tag="TVR04_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1269383.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDDIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(32053..33234)
                     /locus_tag="TVR04_000677"
     CDS             complement(32053..33234)
                     /locus_tag="TVR04_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1269384.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNKPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLVAK
                     PASTAAAAKRQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(33318..34553)
                     /locus_tag="TVR04_000678"
     CDS             complement(33318..34553)
                     /locus_tag="TVR04_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1269385.1"
                     /translation="MKKLIVTLAALMCLITNTSLAEDFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLKAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKDLP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMITTAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFDSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(34877..36115)
                     /locus_tag="TVR04_000679"
     CDS             complement(34877..36115)
                     /locus_tag="TVR04_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1269386.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQEGKLKWDSSVTISNYPYELTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQAQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKIP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            36423..38399
                     /locus_tag="TVR04_000680"
     CDS             36423..38399
                     /locus_tag="TVR04_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1269387.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLNDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSILAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKALRSTLVPPTFVQIGDKDFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQRDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            38463..39962
                     /locus_tag="TVR04_000681"
     CDS             38463..39962
                     /locus_tag="TVR04_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269388.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPAVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            39962..40888
                     /locus_tag="TVR04_000682"
     CDS             39962..40888
                     /locus_tag="TVR04_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269389.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTV
                     VMLVILIAIILMSFIYPMFANYDFGDVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLVIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            40897..41967
                     /locus_tag="TVR04_000683"
     CDS             40897..41967
                     /locus_tag="TVR04_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269390.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGTPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            41960..42883
                     /locus_tag="TVR04_000684"
     CDS             41960..42883
                     /locus_tag="TVR04_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269391.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQAEAERYRKEL"
     gene            complement(43282..44367)
                     /locus_tag="TVR04_000685"
     CDS             complement(43282..44367)
                     /locus_tag="TVR04_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEL1269392.1"
                     /translation="MKHKQLTLSDRTDIQMGIEQRKPFSAIAAKLGKDPSTISKEVRR
                     NLFIKETTVQSNCNTCPLLKKAQLNYETQLSEARTGVALNKEEFYTMDNIVSSAIKKG
                     QHLNHIISSNNLTPSRASSYRYLEKGYLSARPIDFPRVVKFRKRRTSQLPPIPKKDKV
                     GRTYEDFQKHQAKEDLTSWIEIDTVIGRIGGKVLLTFNVSLCNFIFARLLDNKTATEV
                     AKHLYAIKNDFFKADRDFHEFSPVILTDNGGEFARVDDIEMDIRGELKLFFCDPNRSD
                     QKARIEKNHTLLRDILPKGTSFDNLTQDDINLVCSHVNGVRRHALNGKSAYELFTFTY
                     GKDIAILLGITKIDPEDVLQSPRLLDK"
BASE COUNT        12684 a         8161 c        10323 g        13327 t
ORIGIN      
        1 ccatagctca gttggtagta gcgcatgact gttaatcatg atgtcgtagg ttcgagtcct
       61 actggcggag tttggctctg tgtcaactat agtggttgat taacaacgaa catttcgaag
      121 ggaccagttt ggttctctct tttttgtgta ctcaaaaatc tctataacct ctatagtgga
      181 cttacctatt ccagatggta tagagccttg ctttttaggg gatagtatgg taggatagta
      241 gtagttaaga aaagcaccct tagctcaact ggatagagta cctgactacg aatcaggcgg
      301 ttagaggttc gactcctcta gggtgcgtag taaggcaaca ggacatttct gtcctgttgt
      361 ttttttgttt gtctccttat aataaggcta ctaagcatga aaaggagaaa gtataatgac
      421 tgatgattta gtgaggttgt ttgataagat caagcctatt attatgaagc taagacggca
      481 ttattatatt cagctgtggg agctggatga ttggttacag gagggacggt tgatcttgta
      541 tcggttattg gtcacttatc cagaattgat agaggatgag gagaagctgt atcgttattt
      601 taagaccaag ttttcctctt atttgaagga cgtgttgcgg cagcaggaga gtcagaagcg
      661 tcggtttcat aagatggctt atgaggagat tgggtcggta ggccatgcga taccagcagg
      721 tggtttggga gtagatgatt atgtggctta tcagttgatt gtgaaggagg ttgaggagcg
      781 attgacagag agtgagctgt cgcagtttcg ggctttgatc aggggagagc ggtttgaggg
      841 gagacgggcc ttgcttcgca agataggacc ttactttcag gactttactg gtgagaaata
      901 aaaagggtta ccgaaacgag atttgaaagg cttactgtgc agggagatgg ctagactgtg
      961 atggatcttg tgcatctttg agaatgctgg ctgttgtatc aattgataag gcaaatcttg
     1021 atctgtggag agcttggcga gtttatcatg tcagaaatgg cttattaaac tcggtgctct
     1081 gctgctatat ttatttagat ctagtagaaa ttatacatat atcttacttt tagggtctat
     1141 ctgtttttag caagtgttta atcgcttgtt gttaatctta gctgaggtga aaactggttt
     1201 tcttttcctc aataaggtaa agctagagtt tataatagct gtgagaatag ttttagatca
     1261 tcaaaacagc tcataggcta ggagtactgt ctagcttgtg agctgttttt gaagcttgat
     1321 gttaacaaga gatgttatat ggagctttac aggggccgat caggactaaa aaaggtttga
     1381 tataaggctc taatggcctt tttttcatcg gtgctattga tgacaaacat gacggatacc
     1441 tcacttgagc cttgggaaat catagcaata ttgatatgat gttcagatag agcctttgtt
     1501 gcggcagatg tgacaccaat atgacttttc atgttttcac cgactatcat gataatagaa
     1561 aggtttctgg tgatggatac ctcatcaacc tctaattgct ggacaagtct gcgaaggatt
     1621 tcttcttctt tgatgggggt caattctctt tctctaagta caattgatag gtcatcaata
     1681 cctgtaggca tgtgctccca tctgatattg aggtcctcta atatctgaag gagcttgcgc
     1741 ccaaatccaa tttctctgtt catgaggtat ttagataggt taatgctgac aaagtgatca
     1801 tcacctgata taccgacaac gggattggat ttcctctggt gctcaagaac aattgttgta
     1861 cctgggtggc tgggattgtt agtgtttttg atgacgattg ggattttccc tcggtaagca
     1921 gggattaatg cttcatcatg gaggacagaa aagccagcat aggctaactc gcgcatttct
     1981 ctgtaggtta attcagtgat cgtctgtggc tgcttaacaa caccagggtg ggcagcaaag
     2041 atgccattga catctgtaaa attttcatag ctgtcagctg tgactcctgc tgcaataatg
     2101 gagccggtaa tatcagagcc accacgtgag aaggtacaaa tctggttttc atttgtcaca
     2161 ccaaagaatc caggaataac aagaatgtca tcatgatcct ttaaggcctc tagcttatcg
     2221 tagctgattg gaagaagacg tgcatgctgt ggctcactgc ttacgattag acctgcatct
     2281 ttggggtgga agtagcttgc agctaagcca tttgccttga ggtaggcagc tactagcttg
     2341 gcattattgt cctcaccggc cgcaagaaag gtatcgtata aatagggatt atgttctttt
     2401 ggaagccgtg ccaattgctc taaggaagct ttaatttggg tgatgatttt gctatctaga
     2461 gttaggtcat tacagatttg ttggtaacga ttgataatcc attccaaatg cttgtgataa
     2521 tgacggtctg agacgtaggc tttgtaataa gcaatgagtg catcagtcac ctttgtgtct
     2581 gtaggggatc gtttgcctgg tgcggagaca acgatgattt tacgctcagg atcgtccttg
     2641 ataatagcca agaccttttc taactgctgg gcagatgcta aggagctgcc gccaaatttt
     2701 gttaccttca tttgctctcc agtctactta ttgaatatta gagaaattat agcagaaaag
     2761 ctagtccttg tcagtagcct ttttttgcat gttggcgtca aatcaagctt gattatcaaa
     2821 gctaatcgaa aactgtatgg ggacaaaagc cgtaaatgct cttttctgat ggctggaaga
     2881 aatggtagaa taatagcatg acaagatata aagcaattat ttcctacgat gggaccttgt
     2941 tttctggttt tcagagacaa agtcaggcac gtacggtaca agaagagatt gaaaagactc
     3001 tgcaaaaatt gacaggtggt caagggatac agattcatgg agctggtaga acagatgcag
     3061 gtgtgcatgc ttatggtcaa gtgattcact ttgatttgga gcaaaaaaga gaccctgaaa
     3121 agcttcgctt tgcacttgat acccagacac cagatgatat tgatgtgatc agtctggaga
     3181 ttgcagcaga tgattttcac gctcgctacc ataagcattt caaaacctat gaattcttag
     3241 tggatattgg tcgtcctaaa aatcctatga tgcgccatta tgcgacccat tacccttatc
     3301 ccttagatat tgcgaaaatg caggctgcga ttaaggattt ggttgggacg catgatttta
     3361 caggctttac agctgcggga acctctgtta aaaataaggt tcgtaccatt acagcagcta
     3421 ccctcactca ggaccctaaa actgattttc ttgtttttac gttttcaggg aatggctttc
     3481 tttataagca ggttagaaat atggttggga ccttgcttaa gatcggcaat ggtcggttgc
     3541 ccattgaaca aatcaggctc gttttagaga gtaagaatcg gcagctagct ggaccgacag
     3601 cggctggtaa tggtctttat ttgaaggaaa tcatttatga agaataaggt attaacgatt
     3661 gctgggagtg atatattcag cggtggtggt ttgcaggctg atttggcagt gcttcatcag
     3721 ctcgatagct ttgcattttt agctatcacc tgcttaacaa gctgtgatgc taaaggtttc
     3781 agcattcacc ctgttgcgac tgatttgctg gcaaagcagt tgtctagctt agcagctatt
     3841 ccttttcagg caatcaaagt tggtcttttg ccaagacctg aaatagcaga gcaggtggcc
     3901 ctgtttttag agctaaaaaa ggatatccct gttgttttag atcctgtttt agtatttaag
     3961 gaaaatcaag atcagacagt tgtggaaatg acacaggctt tgcgctctct ttttccctta
     4021 acagcagtga ttactcccaa cctaagagaa gcagaacgct tggcagggct tgctattaat
     4081 agcagggagc aaatggtaga agcggcaaaa aagctttatg agatgggggc taagagggtt
     4141 gtgatcaagg gtgggaatcg ttttgatcaa cgagttgccc tagatctatt ttatgacgca
     4201 aaaaccttgt gcttcttaga aaagccagtc ttagccagac aaaacaatgg ggctggctgt
     4261 agctttgcag ctgcaattgc tgcttattta gctaggggac attcaccgtt tagggctgtt
     4321 gagcaggcta aagaccttgt ttttgcagct attcaacagt caaatgatta tggagtcgtc
     4381 ttatgataaa catgaaacgg acaagagagc tagctcttgt gtctatcttg actgccctga
     4441 cagttgtttt gggtaggttt gtgagtattg ccacgccgac agggttttta acccttttag
     4501 atgcaggagt gtatgtgact gcattttctc ttgggaaaaa ggaggggatg cttgttgggg
     4561 gcttatcagc ttttttgctt gatttgattt caggctaccc caattggatg ctgattagtc
     4621 ttgtcgctca tggagctcag gggtatttag caggcctgtc tggcaggtat cgcttttttg
     4681 gagtaggcct tgcttctgtg gtaatggttg gtctctattt tcttgcagct attccaatgt
     4741 atggtatggg cgctgctatt tcaggaattt cggggaatgt tgctcaaaat atccttggta
     4801 taggtgtagg ctatctgctg tatttagggg tcaaaaaaca gctggtcaaa gtgtcagatg
     4861 attaagtagg tgatttaatg gatttaaagg tattgagaga agaagcacgc tctattttga
     4921 ttgatgttgt ggagcgtagt gctatcaaaa aagggcagct gtttgtctta ggtctgtctt
     4981 ctagcgaggt tcttggtggt cgtattggtc agcattctag cttagaggtg ggtgaggtca
     5041 ttgtgaaggt tgtgttggag gaattgtcgt ccagaggaat tcatttagcg gttcaggggt
     5101 gtgagcacat taatcgtgcc ttggtattag aagaaagtgt tgcagaagaa tatcagctag
     5161 aactggtcaa tgtgctgcct agcctgcatg ctggaggaag tggtcaatta gcagccttca
     5221 aatacatgaa gcagccagtt gaggttgaag ccattgctgc tcatgcaggc cttgacattg
     5281 gagatacctc aattggtatg catgttaagc gtgtacaggt accgcttgtg cctattcagc
     5341 gagagcttgg tggcgctcat gtgactgcct tggcaagtcg tcccaaatta attggtggtg
     5401 taagagccag gtatcagcct gatcctattc ggaaataaga acaaaagaaa tagccctatc
     5461 tagcagttta agtctgatga cctgactgct ggatagggct tgtgtgctaa gaaagcaatg
     5521 atttttactg ctaggctaag ggtgatatgg caggcgcagt tggcagcttg atgccctcct
     5581 ttagcaaggc ctcttgatag agcttataaa agctatggta aatcgtaaat tgctgcccat
     5641 tttcagtaaa aatgctaacg cgaaaggtaa attgtccgtt gggattggtt tgtggtccca
     5701 gaatgttggg ttgtccgaca atttgtggga aatttggcac ctctcggtta ttgacagcct
     5761 tgatgatttg ggtcacatgc tctagatcgg ttgaggaata aagtggaata tcgatcaaag
     5821 ctctcatatt gccgcgtgat ttgttgctaa caactgtaat attgcggtta ggaataaaat
     5881 gtaaggtgcc atcaaagcct cgcacttgag tggttcgaat accaacgcta gagatggttc
     5941 cttcaatgcc tgcaatagcg atggtgtctc ctacttcaaa ttgattttca aacagaataa
     6001 aaaagccatt gaccacatca gacaagaagc cttgagcccc aagcccaata gcaacaccag
     6061 caattcctgc tcctgctaaa agactggata ctggaatgcc taaaacactc aaaatccaat
     6121 agatgagaag aaaatagagc acataattta aggtgttgtg aaggagctta gataaggttt
     6181 ttttccttgc ctcagtctgc cttgaataag aaaatgactt ggcgattgcc ttttcaaata
     6241 aggatgtcgt aatttttttg aagatcacaa agaaaatcaa taataaggtg attgacacta
     6301 atttagaaaa cacaagcacc atgatatttt ctaggtgtag ctgattaaag tatgttaata
     6361 taaacgtcat ggtaactcct ttctaccgta gctagtttac caaaaaaagt cctagttgaa
     6421 aatagatcac cacatattaa caagaagagt aatggcttct tgtttaggtt ttattgaggt
     6481 ttttctgacg aacaaaacaa agccattgtg caactggttg cgtatgtctg caaataaatg
     6541 acattaacat gtgtaaaaga ttagagtaaa tgagtctgat tatgagataa ataaaaggca
     6601 aatacttatg caacatgatt ttgcttggtt ttataggctc tggcaaaggg aataaaaatt
     6661 aaaaaaatta ctaatttttt gctaaaaata gtatgcatac cgaaatttat atgttatact
     6721 tctcttatag gtcctatttt tgtttgcaaa cagtacagag aatcatctta tttttttgag
     6781 cgctaacgaa agcgctttcg cagaaagaac ggagtttaca tatggtaaca cataagacaa
     6841 aaagatttct caaagctcta tcagtgacca gcttaactct tggcttggta ctttcaggct
     6901 tgactcctct aacctcagct agccttgcta gtgctcagga ggtgcagtct gctaatcagc
     6961 cggttgctat gaaagacgga gctattttac atgcttggtg ctggtccttt aacaccatca
     7021 aagaaaacat gagtgccatc aaggaagctg gctacacgag tattcaaacc tcacctatta
     7081 atgctgttat taagggtgat ggtggtagta aggacttgaa aaattggtat taccattatc
     7141 agccaacaga ctataccatc gggaactatc aattaggaac agaagaggaa tttaaggcaa
     7201 tggccaagga ggccgacaaa tatgggatca gcattattgt tgatgcggtc ttgaatcata
     7261 ccacctctga gattagtgca gttagcccta atattacagc tttgggtaac tggacacatg
     7321 gaaatgacaa gatagagaat ttcaatgatc gttatcaaat aacccaaaaa tccttgctag
     7381 gactttatga tttcaacaca caaaatcgag ctgttcagga atacatgctg aattatctaa
     7441 aacgagcagt ggctgatgga gcagatggct ttaggtatga tgctgcaaag catatcgaat
     7501 taccaggtga atatggatat ggtagcgatt tctggaaggt tattcttaac aatggtgcta
     7561 aattccaata tggagaaatt ttacagggtg atgcttgcaa cgaagcaggc tatggcaata
     7621 tcatgggagt gacagcgtca aactatggta agctaatccg taaagcgcta ggtcaaggct
     7681 atgtgaaaga ttgggatttg gtgaatttcc aagtgcatgg tgtttcagag gacaagttag
     7741 tcacttgggt agaatctcat gatacctatg ctaacgatga tgaagagtct accaagctaa
     7801 cagatgagga cattaagctt ggctggggaa ttattgctgc ccgtaatgag ggagcaccgc
     7861 tcttcttttc acgtcctcgt ggcggtggcg gccaaaatgg acgcttccct ggaaaaagcc
     7921 aaattggtga tgccggcagt gacttgttta aggacccaac cattgttgcg attaatcaat
     7981 tccgcaatag gatgaatggt caatcagaat atatccgcaa tcctggtatg gaccaaggcc
     8041 tagtcatgat tgaacgcggt caaaagggtg ctgttatcac caacctaacc attgttgata
     8101 agaagttttc ttctacaaca accctagatg acggtgacta caaagacgca gtgactggca
     8161 cagtttatca tgtttccaat cacaacatta ccggtcatct agctaagaag tcagtagctg
     8221 tcttacttcc agcgtaacta tctggcttac agattaagga gtgtttggag tttgggacaa
     8281 aaagagttgc attttagaaa gtcttaacta atgtacttta ttacccagtc taattaattt
     8341 aaaaacgaac aagtctcgtt ttcggaatct tagaaaacaa gacttgctcg tttgttttat
     8401 ttggggtcag tctttttcct ttgaaggtga tgaggttttg gtaatggttc agtcaagagt
     8461 ctgatttttg gaaaccctat ccctactttc acacataaaa aactttaaaa acgctttgta
     8521 atatgataga atgagatgta tctaaattat tttaaggaga aatgacttaa tgtctacatc
     8581 atttgagaac aaagctacaa atcgtggcgt gattacattt accattagtc aagataaaat
     8641 caagcccgct cttgatcaag cttttaataa aattaaaaag gatttaaatg caccaggctt
     8701 ccgtaagggt catatgcctc gtcctgtttt taaccaaaga tttggtgaag aggttcttta
     8761 tgaggaggct ttgaatattg tattgccagc agcctatgaa ggtgctgttg cagagcttga
     8821 acttgatgtt gttgcacagc caaaaattga tgtggtctct atggaaaagg gtcaagaatg
     8881 gacacttact gcagaggttg tcacaaaacc agaggttaag cttggtgatt acaaagacct
     8941 tactgttgag gttgaggctt caaaagaggt tactgatgag gaggttgacg caaaggttga
     9001 gcgcgagcgc aacaatcttg ctgagctagt tgtcaaagaa gatgcagcag tagaaggtga
     9061 cacagttgtt attgattttg taggctctgt tgatggagtt gaatttgatg gtggcaaagg
     9121 ggacaatttc tcacttgagc tgggctcagg acaatttatt ccaggctttg aggatcagct
     9181 agttggtgcg aaggctggtg atactgttga ggttaatgta accttcccag aaaattatca
     9241 agctgaggat cttgcaggta aggctgctaa gtttgtgaca actgttcatg aggtaaaggc
     9301 aaaagaagta cccgagcttg acgatgagct tgcaaaggat attgatgagg aagtcgaaac
     9361 actcgatgag ctaaaggcta agtatcgtaa agagcttgag gcttcaaagg aagcagctta
     9421 tgatgacgct ctagagggtg ctgctattga gttagctgtt gagaatgctg aaattgtgga
     9481 attaccagag gaaatggttc atgacgaggt tcaccgttcc gttaatgaat ttatggctag
     9541 catgcagcgt cagggcattt cacctgatat gtacttccag ctaactggaa caagtcaaga
     9601 agatcttcac aagcagcatg aagcagaggc agacaagcgt gtcaaaacta atcttgttat
     9661 tgaggctatc gcaaaggcag aaggctttga agcttcagac gatgagattg aaaaggaaat
     9721 taacgacctt gcagctgagt acagcatgcc agttgagcag gttcgttcat tgctttcagc
     9781 tgatatgtta aagcatgaca ttgttatgaa aaaagctgta gaagtgatta cgagctcagc
     9841 aaaagcaaaa taagctgtta tgatatagac aagcaagact aagcaagcac ttggtcttgt
     9901 tttactgttg cttcatggtt taaaggcaaa cagttaacac ttctctttga aatgcttctg
     9961 ttatcgcgtt taggagcagt caagctggtt gctgctaggc ttggttcttg ctgactgaga
    10021 gttgggcaaa aagaatactg ttcttccctg ataaaagctt tgacgaatcg gtatttttag
    10081 cgtaaaatag gagagaatga taaaataagg agaactgcct tgaaattaga tgtatttgca
    10141 ggacaagaaa taagcgaact ttctatgatt gaagttgctc gcgctatttt agaagagcgt
    10201 ggtcgtgata atgacatgta ttttagcgat ttggttaatg agattcaaaa ttacctaggc
    10261 aagtctgacg ctgatattcg atatgcttta ccattttttt acactgatct caatacagat
    10321 ggtagcttta ttccacttgg tgaaaataaa tggggtctac gttcatggta tgctattgat
    10381 gagattgatg aggaaatcat caccctagaa gatgaagaag acggcgcacc aaaacgcaag
    10441 aagaaacgtg tcaatgcctt catggacggt gatgaggacg ctattgacta tagcgctgat
    10501 gatccagagg atgaggattt tgttcgtgaa tcatctgata ttgaatatga cgaggaagat
    10561 ccagacgatg aaaaatctga agtagagtcc tacgattcag agctcaatga aatcattcca
    10621 gaggacgatt ttgaagaggt tgacctcaat gaagaggacg aagaagatga ggaagaggag
    10681 gaatagcagg agtatcgcta acctctaaaa gcaacagtaa tatttgacaa atgtcctctt
    10741 atagtttata ttattaatcg ggcacctctt taagaggtca ggtaagctcc ctagttaata
    10801 gggggctatt tttgttttaa taacctagcc ttggttactg gtctcatggc ttagccttat
    10861 gggaagctta gcccccaatc gttactagct aaagtaggac gatcttttaa aaataaaaac
    10921 gagttagtca ggcttaactc aaaaggataa aggagtgtta tgacaaagta catttttgta
    10981 actggcggag tggtctcatc aatcggaaaa ggtattgtag cggctagcct tggacgttta
    11041 ttgaaaaatc gtggcctaaa ggtaacgatt caaaaattcg acccttatat taatatcgat
    11101 cctgggacaa tgagccctta tcagcatggg gaggtctatg tcactgatga tggtgcagag
    11161 actgacttgg atcttggtca ctacgaacgg tttattgaca ttaatcttaa taaatactca
    11221 aatgtgacaa ctggtaaaat ctacagtgag gtgcttcgta aggagcgtaa gggtgaatac
    11281 cttggagcga ctgttcaggt tattccacac attacagatg ctttaaagga gaagatcaag
    11341 cgcgcagcta cgaccacaga ttctgacgtg attattaccg aggttggtgg aactgtggga
    11401 gacatcgaga gtctgccatt cttagaagcg cttcgtcaaa tgaaggcaga tgtcggctct
    11461 gaaaatgtga tgtatattca cacaaccctg ctgccttatt taaaagcagc tggtgagatg
    11521 aaaacaaagc caacccagca ctctgtcaaa gaattacggg gcttagggat tcagcctaat
    11581 atgcttgtca ttcgtactga ggagcctgtt gagcagggga taaaaaataa gttggcgcaa
    11641 ttttgtgatg ttaacccaga agccgttatt gaatctcgtg acgtggagca tttgtatcaa
    11701 attccactga atttgcaggc tcaatcaatg gatcaaatcg tctgtgatca cttgaagcta
    11761 gatgtgcctc aggcagatat gacagaatgg tcagcaatgg ttgataaggt gatgaacctc
    11821 aagaaaacaa caaggattgc tttggtcggg aaatatgttg agcttccaga tgcgtatcta
    11881 tctgtcgtgg aagccctgaa gcattctggc tatgccaatg atactgccat tgagcttgat
    11941 tggattaatg ctaatgactt aacagccgaa aacgctaagg agctgcttgg agcggctgat
    12001 ggcattattg ttcctggtgg ctttggtcag cgtggaacag aaggaaaaat tcaagccatt
    12061 cgctatgcgc gtgagcatga tgtaccaatg cttggcattt gcttaggcat gcaattaacc
    12121 tgtgttgagt ttgctcgtca tgtcctaggc atggaaaaag ccaattcgtt tgagctggat
    12181 ccagatactg cctatccaat cattgatatt atgcgtgatc aaattgatat tgaggacatg
    12241 ggagggacac tacgtctggg tctataccca tgtaagctaa agactggctc aagagctgca
    12301 gcagcctaca ataaccaaga ggtggtgcag cgccgtcacc gccaccgtta cgaatttaac
    12361 aataaattcc gtcaggactt tgaagcagca ggctttgttt tctcaggtgt ttcgccggac
    12421 aatcgtttgg tagagattgt agaattacca gagaagaaat tctttgtggc agcccaatac
    12481 catccagagc tgcaaagccg tcctaatcgt cctgaagagc tatacactgc ctttgttaca
    12541 gcagcagtga aaaataaaaa ccaaagcctt taagtctagt atgacgtaag aggctatcct
    12601 tgagccttat ttaggtgctg agaatcagca gctttgatag gcttattaag tttttgagtg
    12661 gctgatgaga tggtgacatc agccattttc atatagcaaa aagcaccatt ttacctccta
    12721 ttaaatgctg tcagcggact tcctcttgat ctggtcaaag ccattttgaa ggtagcttgt
    12781 atattcttta aactattgag cttcaattcc tctaaaagcg ctttagctac tggctggctt
    12841 gagatttggc cttaagaagg cagtaaaaag gtatcggtta tttttagcat aaagctttct
    12901 tttttccata ttttcttgta gaatagtcgg tatgaaaacc attcgattat caaagtattt
    12961 tggcatttta ctgctcttgt tgaccctggc tagtgtggga gctagctttt atttcttcca
    13021 tgttgctcag gtgcgtgagg aaaaatcatt tatcaacaat aaaaaacgaa ccccaggcaa
    13081 ccctttgtat ccagcagagc ttgcctttga cagtcttgtg cgtgaaaagc gcagcattgt
    13141 caatagaggc catcagcaaa cagcctggta tttgcctgcc tcgcaggata ctcataagac
    13201 agctattgtc gttcatggct ttacaaatga taaagaagac atgaagccct atgccatgct
    13261 ttttcacagc ctaggctaca atgtgctgat accagataac gaggctcatg gtgagagtga
    13321 gggtgacttg attggctatg gttggaatga tcgcctaaac ctacttgcct ggattgattt
    13381 gctcgttagc gaggataaag agagtcagat tagcttattt ggtctgtcta tgggggctgc
    13441 aacagtcatg atggcaagtg gtgagcagct acctagtcag gttgtcaata tcattgagga
    13501 ttgtggctat accagtgttt gggacgaatt gaaattccaa gctaaggcca tgtacaatct
    13561 accagccttt ccattgctat atgaggtttc agccctctct aaaattcgtg ctggctttag
    13621 ctatggtgag gctagctcgg tgaagcaatt ggctaaaaat aagctgccag tcctctttat
    13681 tcatggcgac aaggacactt ttgtcccgac agagatggtc taccaaaact atcaggcaac
    13741 aaaaggtcct aaagagctaa tggttgttaa gggggctaaa catgccaagt cttttgagac
    13801 caatcccgac cagtacaagg aaaagattgc ggcctttttg caaaaatatg agaaataagt
    13861 attgacagta aagctcccag ctgatataat tttatatgtc gctgatgagc agcggggatg
    13921 gcggaattgg cagacgcgca ggactaagga tcctgtgacc gctttaggtc gtgtgggttc
    13981 aagtcccact ctccgcatcg cagaggtgaa tcttggattc atcttttttt atttcctaaa
    14041 aagactgctg ctagccaaat actcaattgt gagcctgtga taagatgaat cgagaaaacg
    14101 ctttaagctg atgaggggct ggaaatttct tgaaaattgt gctaaaatga acaatgtaaa
    14161 tggggttaac ccaaaatata agaggaggct tattaaaatg ccaatcgttt cagcagaaaa
    14221 atttgtccaa gcagcacgtg ataacggcta tgctgttggt ggatttaaca caaacaacct
    14281 tgaatggact caagcgatcc tgcgtgcagc agaagctaaa caagctcctg ttcttatcca
    14341 aacctcaatg ggtgcagcta aatacatggg tggctacaag ctagctaagg ttcttatcga
    14401 aactcttgta gaatcaatga acatcactgt accggttgcg atccatcttg atcatggtca
    14461 ctatgaagat gctcttgaat gtatcgaggt tggttacact tcaatcatgt ttgacggttc
    14521 acaccttcca gttgaagaaa accttgagaa agcacgtgaa attgttaagc tagcacatgc
    14581 taagggtgtt tcagttgaag ctgaggtagg tacaattggt ggtgaagaag acggtatcat
    14641 cggtagtggt gagcttgctc cgattgaaga tgctaaggca atggttgcta caggaattga
    14701 cttcttggct gcaggtattg gtaatatcca tggaccatac ccagaaaact ggactggtct
    14761 tgatctagat cacttgaaga aattgactga tgctgtacca ggcttcccaa tcgtgcttca
    14821 tggtggttca ggtattcctg atgaccaaat tcaagcagct atcaagcttg gtgttgcaaa
    14881 ggttaatgtt aatacagagt gtcaaattgc atttgctaac gctactcgtg cctttgcgcg
    14941 tgattacgaa gcaaacgttg cagaatacga taagaaaaaa ctctttgacc cacgtaaatt
    15001 cttggcagat ggtgttaagg cgatccaggc ttctgttgaa gaacgtattg atgtctttgg
    15061 ttcagcaaac aaggcttaat gactgctaaa cgtgattaaa tcagggttta tccgcaagga
    15121 taggcctttt tatagttcct tcgcctaatc cccttgccga taaagaatag ccctacttga
    15181 gcgattatgt ctttgttttt gaggtgtgtg ctagcagatg tctgtggtaa gggctgctct
    15241 gctataactg gaaggatctt gaacgttctt gagaaaaacg ctttgtacta tccaaacatt
    15301 accaagcctg tgctgaaata ggtgactcat gatatgcttg ctgaagcaga acctttgaca
    15361 ctatcagctt ctgctgcgca aatgtctcct tatttatcga ccctattagt ttaaggtgag
    15421 ctgagacagc tattgctaag gcttcattcg gtagctgtct atgcctctct ggtttagaga
    15481 gtttttgatg agatcacagg tggtgagaat aaaaggaatt ttgtcatgta gcatcttatt
    15541 tgttgggttt agttaggtca actgttcata gctttatttt tacttatttc taatgaaata
    15601 ctttttgttt tacaatatag ttatatttta gtatgatttg gttaaaaaaa taaaaaggag
    15661 gaattgctat gacagctcta agcatttcaa aaaggtcttt tttgatgagc ctcgggctat
    15721 tatgcgtctg tattggccta gcagtcggta ctagccatac agcttttgcg catgtatcaa
    15781 ccttttattg gaataggtct tggtacctgt ctcaacaaaa taaaggtact gatgaagagg
    15841 ttgaacaaaa aaagaaggaa ttaattgaaa agattgaaac ttctagactg tataggttta
    15901 tcaaaaataa ttatattgat actattaata gtcatgtttt tctctataag cttttatatc
    15961 ttgaagagca cattgatata ttagttgcaa gagctaaggc tgaagccgaa tctggaatta
    16021 tacttgatga ctaaagatca tcgctagcca gcagtcttat actgaccgag attttcaatc
    16081 tcacaaaaga ctaaacaaga agcactcctc aggctaatct ccctactaat gtggttgtgt
    16141 gatgtcttgt ttagtctttt ttagtgcatg tttataggat ttcagctagg cagctaggca
    16201 actacagcaa agcctgttaa atagcctcta tttcttagag tagttttagc gttctaagag
    16261 aaggctttcg agctgacagc agcccttaga catttgtgat agatagggta gcagctttat
    16321 tgattcttat agatctattt ataggagagg agcaagtgag tgcttagcta ttaagaggga
    16381 cattttgctg cttagtggct aaggcctgca gatgtaaaaa atagcttgcc aaaaggtaag
    16441 agttgtgata gactaggtaa gtatgtggtg ctagcacatc cgtaaacata ttctacctag
    16501 gaggaaatag attacaatgg ctaaagtatg ttatttcaca ggtcgtaaga ctgtatctgg
    16561 taacaaccgt tcacacgcta tgaaccaaac aaaacgtact gttaaaccaa atcttcaaaa
    16621 agttactatc cttgttgatg gtaaaccaaa aaaagtttgg gcttcagctc gtgcgcttaa
    16681 atctggtaaa gtagaacgca tctaatcgaa ataagcctta gggctttttt ttcttagtcg
    16741 ttttcagaaa aagcctagaa aagcatgata gaggtgacct ttcttcgctt atatcttttt
    16801 acattgacct tgaattatga taaaataagc tgataaaaac tttttgaggt agtaactatg
    16861 actgtaaaaa ttaatacaaa agatggtcta attgagctat ctgatgacgt tattgcaact
    16921 gtcgttggag gttcagcaac ggaaattttt ggcgttgttg gtatggctag taaaagtgct
    16981 ctaaaagata actttcaatc gctacttcgc aaagaaaatt atgctaaggg tgtagttgtt
    17041 aagtcaacgg atatgggtat ttcagttgat gtctatactg ttatgagcta cggtgttaaa
    17101 attagtgagg tatccaaaaa tattcaggag cgtgtgaaat ttaaccttga gagtcagctt
    17161 gggctttctg cggatatggt gaatgtttac gtgcaaaata ttaaagttgt aggagaaaat
    17221 tagtgtcaaa tattacaaca agcttattcc aagaaatggt ccaagcggca gcaactcgtc
    17281 ttggtaaaca agcagaatat gtcaattcct taaacgtttt tcctgtacca gatggtgata
    17341 cagggactaa tatgagcatg acaatggata atggtgctaa agaggttgct gataagccgg
    17401 cttcaacggt tggtgaggtt gggcagatcc tatccaaggg tctcttgatg ggggcgcgtg
    17461 gcaattctgg tgttattacc tcgcagcttt ttcgtggctt tggccaaagt atcaagtcaa
    17521 aagaggagct gacaggtaag gatttagctc aggcctttca gatgggagtt gaggttgcct
    17581 acaaggcggt gatgaagcct gttgagggga ctattttgac cgtttctcgt ggtgcagcaa
    17641 cagcagcctt gaaaaaggca gaccttactg ataatgccat tgaggtgatg caagcagcgc
    17701 tagatggtgc aaaaggagcc cttgcaaaaa caccagacct gctgccagtt ttaaaagagg
    17761 ttggtgttgt tgactcagga ggtcaaggtc ttgtctttat ttacgagggc ttcttgtctg
    17821 ccttaaatgg tgattatgta gcttctgagg actttaaggc cactcctgcc aatatgtctg
    17881 agatgattaa ggctgagcac cacaaatcag ttgcaggtca tgttgctacc gaggatatta
    17941 cctatggcta ttgtactgag attatggttg ctctaaagca gggtcctacc tatgttaaag
    18001 aatttaatta tgatgaattt cagggctatt tgagtgggct tggtgattcg cttttagtag
    18061 taaatgatga tgagatcgtt aaggttcacg tccatacaga ggatccaggg ctagtgatgc
    18121 aagagggtct gaagtacggc tcactgatca aaattaaagt agataacatg cgcaatcagc
    18181 atgaggcaca ggtacaaaaa atagacaatg agcctactaa ggcagaggca aaagagtttg
    18241 gcctgattgc tgttgttgca ggtgatggcc tggcagagat ttttaaggca cagggggttg
    18301 actacgttat ctcaggtgga caaaccatga atccatctac tgaggatatt gttaaggcta
    18361 ttgaagctgt caatgctaag caggtgatta tcttaccaaa caataaaaac atcttcatgg
    18421 cagcccaatc agcagccgag gttgtggata ttcctgcggc tgttgtggag acacgtacaa
    18481 ttccacaagg ctttacgagc ctgctggcct ttgatccttc aaaaactttg gaggataatg
    18541 tagctgatat gacagcaagc ctgtctgatg tggttagtgg aagtgtgact ctggctgtgc
    18601 gcgatacaac gattgatggc cttgatattc atgaaaatga ctttttagga atggtcgatg
    18661 gcagcattgt agtgtcaaat ccagacatgg aagctaccct aaagactacc tttgatcaca
    18721 tgattgatga ggacagcgaa atcgttacga tcttcattgg tgaggatggc agcagtgaag
    18781 tggctcaagg tcttgctgat tacctcgagg aaacatatga ggatatagag gttgagttgc
    18841 atcagggaga tcagcctgtg tatccatacc ttatgagtgt tgaataatga atagaacaaa
    18901 gagaggagtt aggcagtgct tggctccttt tgtcttcaca aggaagatgt gaccattaag
    18961 aaacagtgat tacaacctgg cgtcaagtgt agacttttta gtggtctcta gcagctgtaa
    19021 aaccggctga tagacgttga gatttttatt gacaaaagac aaaaatattt tataattgtc
    19081 ttataacaat gaggcaatca taaaaagccg tatagctatc gagctagggc ttaataagga
    19141 ggagattaac atgttagaag ctattttgat tattggattt ctagtgattg tgatattatc
    19201 cattatggca agcacgctgt atgtggtgcg ccagcaatct gttgctatta tagagcgctt
    19261 tggtaaatat caaggcacag ctactagtgg tattcatatt cgattgccct ttgggattga
    19321 ccgcattgct gcgcgtgtgc aattgcgctt gctgcaatca gagattatcg ttgaaacaaa
    19381 gaccaaggac aatgtttttg tgacgctaaa tgttgcaact caatatcgtg tgaatgagca
    19441 aaatgtgata gatgcttatt acaaattgat caagccagag gctcaaatta ggtcttatat
    19501 tgaagatgcc ttgcgttctt ctgttccaaa gctaacctta gatgaattgt ttgagaaaaa
    19561 agatgaaatt gccttggagg tgcagcatca ggtagcagaa gaaatgtcaa cctatggcta
    19621 tattattgta aagaccttga ttacaaaggt tgagccagat gctgaagtca agcagtctat
    19681 gaatgaaatt aatgctgctc agcgtaagcg tgtggcagca caagagttgg ctaatgctga
    19741 taagattaaa attgtaactg cagcagaagc ggaagccgaa aaggatcgcc tacatggtgt
    19801 cggtattgcg caacagcgta aggctattgt tgatggcttg gctgattcta ttcaagaatt
    19861 gaaggaggct aatatttcat tgaatgaaga gcaaatcatg tcaattcttc tgaccaacca
    19921 gtacttagat accctcaata cctttgctgc taagggtaat cagacccttt tcctaccaaa
    19981 tactccaaat ggtgttgatg atattcgcac tcaggtgcta tcagccttaa aaacaagata
    20041 acatatatta agcaagctgg tcagcatcag cttgcttttt gtatgatggc tcgtcaatgt
    20101 tcttgaaaag taaggcagtc gtctttattt cactattgtc ttaagcataa tggctattga
    20161 aaaatgttgc tatgtctgaa atgctagcaa gaatcacagg ctcaaacagc ttggaagcta
    20221 gaccaattgc aatgggttgt ttcaatcacc tttgaagctt agccgctaag agagcaaatg
    20281 agggaacaaa gtgagttcaa gtgccgcttt gtgctgtgct aaaaggttag ttttcttggt
    20341 atccggttgc ttgaaaatgc tgaagcatgg acctaaaagc tgagtgtagc atttcctaac
    20401 tactgctatt ggcagctcta tcagatgtgt gtgtcctcag cttgttgatg gttaacaatg
    20461 cttaaagctt tcttttcttg ggcatcaaaa aatgattaag acggagggat ggtgtcctaa
    20521 tcatttttta tctgacttaa atttggagag ataaaaatag aatactattt tttaccgtaa
    20581 cgtttgtgct cgtgaataat cttcagagca cgttttttag ttttaatatt tgggcttttt
    20641 agtcttctgt aagctgacgc gaggtcagtt ttttcggcca tgctatcctc ctactaaaat
    20701 atattattaa cgttaataaa gacagtatag cacaaagtta ttaaccagta aagtattttg
    20761 tgttgaaatt ttagaataga gatcaagctt aacagttacc gtctcatttg agaaatgata
    20821 tttgtagacc agtcgcttta gaagctttga agagtgtatc agcctgctct tccaaaagga
    20881 ggcttattat ctgtacctgt tgagtgaggg aaatagtatt ataatcagtt tttaatctga
    20941 agtattagca ggtgtgactc atcaaaaaaa agccattcta acgcctatgg ttagattggc
    21001 ttttaagctt atgacaaaaa gcgctgtaaa aatgctttgg ttcgatcctg ctttggctgc
    21061 tcaaagagct gctttggtgt gccttcttct gcaatgagcc ccttatccat gaaaatgaca
    21121 cggtcagaaa catctcttgc aaactccatt tcgtgagtga caataatcat ggtcaagcct
    21181 gatttagcca gatcctgcat ggtttttaag acctctgcga ccatttctgg gtcaagagct
    21241 gatgttggct catcaaacag catggcttca ggattaacag ataaggcacg agcgatggcg
    21301 acacgttgct tttgtccgcc tgatagctgc ttaggcttgg cttgccagta ttgctcggtc
    21361 atgccaactg ccttgagatt ttccttggcg attttttcag cctctgatcg ttctctcttg
    21421 aggacagttg tttgagctac gattgcattt tctaaaacgt taagattttc aaagagattg
    21481 aaggactgga aaaccatgcc caatttttca cggtaatggg tcaggttgta gccttctgca
    21541 agcacattgt caccatgaaa gagaatttct ccggcgctag gctcttctaa taggttgatt
    21601 gagcgtagga gggttgattt gcctgatcca gatgaaccga tgattgaaat cacctctcct
    21661 ttattgacgg ttagcgagat gtcctttagg acctcgttat ttccataaga cttttttagg
    21721 tttttaattt caataatagg attagacatt tgggacctcc gaaacttgca tttggtttgc
    21781 tccggtagtg taagtatcag catcgaagcg acgttcgata taacgaagga tacgcgttac
    21841 cgtaaaggtt aggacgaagt aaataatagc gataatggta aaggtttgga agtattgata
    21901 agtctgagta gccactgtat ttcctgagaa atatagctca accactgaaa tgacattcaa
    21961 gacagaggtg tccttgatat tgatgacaaa ctcattacca gtagcaggta ggatattacg
    22021 aaccacctga ggaaggacaa tctgacgcat ggtttgccca tgagtaaagc caagggctgt
    22081 tgctgcttca aattgccctt tgtcaactgc aaagataccg cctcggacaa tttcactcat
    22141 gtaagcacca gtgttgattg agacaatgac gatagctgct agtgtgcggt caatggaaat
    22201 gccaaaggcc tgtgcagtac cgtagtagat caccattgat tgaacaatca ttggcgtacc
    22261 gcgaaagact tcgatataga cgttgagtag tccaccaaag agcctttgag ctagcgctgc
    22321 caatttgccc ttagcctttg gtgctgtacg gtaaatacca atcaagagac cgatgaaaag
    22381 tcctgtgata gtgccaatca tcgaaatcag gagggtcatg cctgtcccgc gaaggaactg
    22441 cttccagttg ctttgaaaga ttgaccaggt ttgcttgata aaggagggct ttgcttcatc
    22501 agctttgggc tcgcttggct gctgttggat catcttgtcc atcaaggcaa ggcgttcctt
    22561 ttgagaaatg gcatcaagca cttgattgac tgctgtaagg cggtcgtctc cttttttcat
    22621 gccaatggca atggcagcgt ctgactccga aacggtaaat ccttttgtta gagtgatcat
    22681 tttaaaggct ttgttggcag tctcggctgt cattgcctca gggcgctcgg agatatagcc
    22741 atcaatcact ccagaggtta gagcctggcg catttgagaa aaatctccca ttggtgtttg
    22801 aagctttgcc ccctctagct gtggcagcag gttgacatgc cacacgccct gttgagcagt
    22861 taccttagca cctgaaaaat ctttgataga acgagccttg gcatacttac catttgaggc
    22921 gacaacaatg actggctcgc tggtgtagta gctgttagaa aaggcaattt cttttttgcg
    22981 ctctgctgtt gggctcatac cagctgcaat taaatcaatc ttacctgagg tcagagccgg
    23041 aataagacct gtccacgagg ttttcacaac caataagtct ttgtttaatg cttttgcaat
    23101 ttttttagcg atttgcacat catagccatt ggcgtattgg ctggttcctt cgataggaac
    23161 agcgccattt gacgaatcat cttgagtcca gttaaatgga gagtaagccg cctccatacc
    23221 aactcgtaaa tagtgatctg cttgcacagt acctattcct ccaagaaaaa taagtaaggt
    23281 ggccaagcag ctaaggacta gctttttcat ataggtctcc tttttaaaaa acgtgtttaa
    23341 tactattcta tagtaattta caagctattt caatacattg gttaaaagag gtgattattt
    23401 attcataaaa cgagtgaaga aatgattaaa aataagcttt ttcttatgaa atcactgatt
    23461 tattaacggt gtcatttatg gtacaatatg aacaagcaaa aaaagcaata cctcattgct
    23521 gttgcttgat gactgtggtt gcggcttctc cgctggcaat ggaggaggaa gtggtgttct
    23581 tttaggacgg gctagatatg agagcctttg ttagaaggag gaaacatgtt atttattgaa
    23641 ttgctgaagg ccatcttctt tggtgttatt gagggagtta ctgagtggct gcctatttcc
    23701 agtactggac atctgatttt ggtccaggaa tttatcaggc ttcatcagga taaggccttt
    23761 atggagatgt ttaatattgt tattcagctg ggagcgatta ttgcggttat tgttatttac
    23821 tttgaacgct tgaacccttt tcagcctggt aagagcccac agcaaatcag gctaacctgg
    23881 cagctgtggc ttaaggttgc tattgcttgt attccgtcta ttatcattgc agtaccactt
    23941 gatgattggt ttgacgctca ttttaatcat atgcttccta ttgctattgc attgattgtt
    24001 tatgggatag cctttttatg gattgaaaag agaaatcaga cacttgagcc gcgagtcgtc
    24061 aagctatctc gtatgtccta taaaacagcc ttcttcattg gctgctttca ggtgctgagt
    24121 attattcctg gcaccagtcg ttcgggagca acgattttag gggctatcat tcttggagca
    24181 agcaggacag ttgctgcgga ctttaccttc tttttggcca ttccgacaat gtttggctat
    24241 agtggcctaa aagctctgaa gttttttatt gatggcaacc atttgaccct ctcgcagcta
    24301 ttagtgcttt tagttgccag cctaacagcc tttgcagtca gtctgtatgt gatcaaactg
    24361 ttaacagatt atgttaaaaa gcatgatttt acagtctttg ggcgttatcg tattgtgttg
    24421 gggagcttat tgattgtcta cagtctgttt aagtcacttt tttagaaata gttaggcagt
    24481 tttcctagga aggctgcttt tacttgctgt aaggctagtc ataaattgcg aaatcatagt
    24541 atttctagta taataaaatg actacgcctg cgaggtattt tacaatggaa atgaaacaaa
    24601 ttagcgagac aacgctaaaa ataacaatta gtatggacga tttagaagaa agggggatgg
    24661 agctcaagga cttcttgatc cctcaagaaa agacagagga gttcttttat gctgtcatgg
    24721 acgagttgga ccttccggac aattttaagg acagtggtat gcttagcttt cgagtgactc
    24781 caagaaagga tcgcttagat gtttttgtga ccaagtcaga cctcaataag gaccttaatt
    24841 ttgaggattt ggcagaccta ggtgatattt ctcaaatgac tccagaggat tttttcagga
    24901 gcttggagca gtctatgcgt gaaaagggtg atgtcaatgc ccatgaaaag cttgaaaaaa
    24961 tcgaggagat catggaggac gtggtagctg ctaccttggc tgagcaagca gataataagg
    25021 aagctgctga gcttgaagag ccgacagagc cacttgatta cgttcactat gttcttgatt
    25081 ttgcttctgt gcgagacgct gtttgctttg ctaaggcgat tgattttccg atcgaggcct
    25141 ctgaattgta taagggtcct cgtcattatc acatgacgat tttacttgat gtgcaaaaca
    25201 agcctgccta ctttgccaat gtgatgtatg ccagattgat tgagcatgct agtcctggta
    25261 caaaaacaag agcttatttg caggagcatg gttgtcagct catttttgat ggtgctgttg
    25321 aggagctaca aaaaatcagg ttggggtagg gtatgatgat ttcgttcacg atagatgatg
    25381 tcttggtttt aattggtgcc ttgctgatgt cacttttatt aacgccaatt gtacgttttc
    25441 taagcattag agtcggtgtg gtagatactc caaatgctag acggattaat aaggttccca
    25501 tgccgactag tggaggcttg gctatcttta cttcctttgt gattgcgagt ctggtactga
    25561 tgcctctggc atcaaatggt gctcatattg gcgggcaaac ctattttcag tatattttgc
    25621 cagttgtctt aggaggcttg gtggttaccg taacaggctt tatagacgat gtgtatgagc
    25681 taagtcctaa gctgaaaatg ctgggaattg tcattggtgc cattattgtc tgggccttta
    25741 ctgactttaa atttgatagc tttaagattc cttttggtgg acccttgctg gcttttgatc
    25801 ctttcttgac cttcttttta accgttcttt ggattatctc aattaccaat gcgattaatc
    25861 ttattgatgg cttagatggt ctagtcagtg gtgtttcgat tattagctta gtaacaatgg
    25921 ctattgtggc ttatttcttt ttgccactga caaacttctt tttaaccctg acgattttaa
    25981 tcctgattgc gtcaattgct ggctttttcc cctataatta ccacccggct attatttatc
    26041 ttggggatac gggggcgctt tttatcggct ttatgattgg tgtgttatca ttgcagggct
    26101 taaaaaatgc aactgcggtg gcagttgtta caccggttat tattttaggt gttccaatta
    26161 tggatacgat tgtggcgatt attcgtcgaa gcctgtctgg aaagaaattt tacgagcctg
    26221 ataagatgca cctgcatcat cgtctcttgt caatggggtt tacacatcgt ggtgcagtgc
    26281 tggttgttta cggtattgct atgctttttt ccttgatttc tctgttgctg aatgtctcta
    26341 gtcgtattgg ggggatccta cttatgttag gacttttatt tgccctagag gtctttattg
    26401 aaggtattga aatctgggga gaaaaacgaa cacctctatt caatctcttg aaatttattg
    26461 gtaatagtga ttaccgtcag acgacgcttt caaaatggaa gcaaaggaaa tgatttcaga
    26521 caagtaaaaa gcctgctgag gctttttttg ttataatgaa gatagtgaaa gcattaggct
    26581 attttcagga aagaagacac tgaaagagcc taatagaaat gatgaggtat acaatgtcaa
    26641 ttcttgaaat caacaatttg catgtttcga tagaggataa agagatttta aagggggtca
    26701 atctgaccct aaggacaggt gaaattgctg ctatcatggg accaaatgga acagggaaat
    26761 caacactgtc agcagcgatt atgggcaatc ccaactatca agtgacagag ggtgagatct
    26821 tactagatgg tgtcaatatt ctggagctag aggttgatga gcgtgctaga ctgggacttt
    26881 tcctagcgat gcaatatccg tctgagattc caggaattac caatgccgaa tttatgcggg
    26941 ccgctatgaa tgcaggtaaa gaggacaagg ataagatttc tgttcgtgat ttcattacca
    27001 agctagatga gaagatggcc ttgcttggta tgaaggagga aatggcagag cgctacctca
    27061 atgagggctt ttctggcggt gagaaaaaaa gaaatgaaat cctgcaattg cttatgctgg
    27121 agcctaagtt tgcgctgtta gatgagattg actcaggcct tgatattgat gccctaaagg
    27181 tggtgtcaaa aggggttaat gagatgcgtg gtcaggcatt tggtgcgatg attattaccc
    27241 attaccagcg cttgcttaat tacatcactc cggacttggt gcatgtcatg atggatggtc
    27301 ggatagtcct atcaggagat gctgcacttg ctacacgact cgaaaaagaa ggctatgcag
    27361 gcattgctga ggagctaggc attgactata aagaagaggt ctaagctgca aggctgtcta
    27421 aggcttcgcc atagctgtgc tgattagtat gtttgctgat gattgaaaag cttaccagaa
    27481 aaaaaggaag gatagatgac aaaagaaaag atattggcct tttctcaagc gcatgctgag
    27541 cctacttggc tgcaagagct gcgcttaaag gcctttgatg tgatgccaca tttagagctg
    27601 cctactattg aacgggttaa atttcaccgt tggaactttg gtgatggtag cctaacagaa
    27661 agcactactt taggaactgt tccagatttt atggcctttg gtgataatcc taagctggtt
    27721 caggtcggaa cacagacggt tcttgagcag cttcctatgg aattgatcga aaagggggtt
    27781 gtttttacag accttgctac agctttagag gagattccag agcagcttga ggctcatttt
    27841 ggctctgcct tagcctttga tgagcataga ctggcggcct atcatacggc ttattttaac
    27901 agtgcggctg tgctatatgt tccagatcat gttgagattg agcagccaat tgaagggatc
    27961 ttcttgcaag acagtgatag tgatgtcccc tttaacaagc atgtgctcat cattgcaggt
    28021 aaagaaagta agctgaccta ccttgagcgc tttgagtcta taggagacaa gacccaagca
    28081 gctagtgcca atattagtgt tgaggtcatt gctcaggcgg gaagtcagat taagttttca
    28141 gcgattgatc gtctaggtga tcaggtgaca gcctatatca gtcgcagagg ccgcttagat
    28201 cgggctgcga ccattgattg ggcgcttgct ctgatgaatg aaggcaatgt cattgctgat
    28261 tttgatagtg atttgattgg tcaaggctca caggctgatg tgaaggtggt tgctgcttca
    28321 agtggtcgcc aagttcaggg gattgatacc cgagtaacca actatgggaa gcatacggtt
    28381 gggcatattt tacagcatgg ggttatcttg gagcgtggga cattgacatt taatgctatc
    28441 ggtcatatca ttaagggagc aaagggtgct gatgcccagc aagaaagtcg tgtcctaatg
    28501 ctgtcagatc aggctcgctc tgatgccaac cctattctct tgattgatga aaatgaggtg
    28561 acagcaggcc atgccgcctc tatcggccag gtggatcctg aggacatgta ttatctgatg
    28621 agtagaggac tagaccaaga gactgctgag cgtcttgtta ttcgaggctt tcttggtgca
    28681 gtggtggcag agatccctgt gccgtcggtt cgtcaggata ttatcactgc cttagatgat
    28741 aagctggcac gtcgttagtt actagtcaaa gaaaggagtt atcattgttt gatcctaatc
    28801 aaatcaaagc agactttaaa ctacttgacc aatgtgtaaa tgatgaagct cttgtttact
    28861 tagataatgc agcgacaaca caaaagccac aggcagtgtt agagaccctg caggcctatt
    28921 atcaaaaaga taatgccaat gttcatagag gtgtccatac cctgtcagaa agagcaacaa
    28981 gacagtacga agctagtcgt caaaaggttg ctgactttat tggagctaag tcaagtaagg
    29041 aagtgatttt cacaagaggg acgacaacca gcttaaattg ggttggaaaa tttgctgagc
    29101 aggtcttaaa gccaggtgat gaggtgctga tttcgattat ggagcaccat gcaaatatcc
    29161 ttccttggca gcaggtctgt caaaaaacag gggcaagact tgtctatgct tatcttaaga
    29221 aaggcaagct agacatgaat gatctgcaat caaaattggg tgctagcacc aaatttgtca
    29281 gtatcgccca tgtctctaac gtgttaggct gtgttaatcc gattcaggag attgcaaggc
    29341 ttgctcatgc tcagggtgcc tatcttgtgg ttgacgctgc acagtcagta ccacacatga
    29401 ctgttgatgt gcaggagtta gattgtgatt tccttgcctt ttcaggccat aagctgctgg
    29461 gaccgactgg cattggtgta ttgtatggca aggaggctct tcttaaccaa atgaatccag
    29521 ttgaatttgg tggagaaatg attgattttg tttatgagca ggaggcgact tggaagcctt
    29581 taccttggaa gcttgaagca ggaacacccc atattgctgg agctattggt cttggtgctg
    29641 cgatttcgta tttggaggct ataggaatgg atcaagttca tgctcatgag gctgatttag
    29701 ttgcttatac cttgccaagg ctacaggcta ttgctggctt gacggtttat ggtcctgaac
    29761 gagcagatga acgctcaggt gtccttgcct ttaatataga tggcttacac ccacatgatc
    29821 ttgcaacagc tttagattac gagggtgttg cagttagagc aggacatcat tgtgctcagc
    29881 ctttgcataa gtacttggga ctgcattcaa cagttcgtgc tagcttttat ctttataata
    29941 cgagggagga ttgtgatcgc ttgatagaag ctattttaaa ggcaaaggag ttttttaatg
    30001 gcactttcta agttaaacag cttatatatg gctgttgtgg ctgatcattc aagacatccg
    30061 catcatcatg gacagcttga gggcgtagag gcagtccagc ttcataatcc tacttgtgga
    30121 gatgtgattt cactgactgt caaatttgct ggtgacagga ttgaggatat tgcctttgcc
    30181 ggtgatggct gcacgatttc gactgcttcg tctagtatga tgacagatgc tgtccttgga
    30241 aagacaaagg aagaagcatt ggccctagct gatatttttt caaatatggt tcagggaaat
    30301 gatgatagca atcaggctct cttgggtgaa gctgagctat tggctggggt tgccaacttt
    30361 ccacagcgta tcaaatgctc aaccctggcc tggcatgctc tcaagcaggc tattgaaaaa
    30421 agcgaggagc tctaagtctc tctcatttag taacgtataa aggaaaatag aaaatgtctg
    30481 atataaatga aacagtagcc ccccagccaa ttgatttagg tgattatcaa tttggctttc
    30541 atgatgatgt tgagcctatc tactcaacag gtaagggctt aaatgaagca gttgtgagag
    30601 aattatcagc tgctaaagat gaaccagagt ggatgctgga atttcgccta aaatcacttg
    30661 aagcctttca taaaatgccc atgcaaacct ggggcgcaga cctttcagat attgattttg
    30721 atgatatcat ctattatcaa aagccatctg acaagccggc tcgctcatgg gacgatgttc
    30781 cagataaaat caaggaaacc tttgagcgca taggcattcc agaggcagag cgagcttatc
    30841 tggcaggagc ctcagcacaa tatgagtctg aggtggttta ccacaacatg aaggctgagt
    30901 ttgaaaagct gggcattatt tttacggata cggattctgc cttaaaggaa tatcctgagc
    30961 tatttaagca gtattttgct aagctggtac ccccaactga caacaaatta gccgccttga
    31021 attctgctgt ttggtcagga gggaccttta tttatgtgcc aaagggggtc aaggtagata
    31081 ttcctttgca aacctatttc cgcatcaata atgaacacac cggtcagttt gagcgtacct
    31141 taattattgt tgatgagggc gccagtgtgc attatgtgga gggctgtaca gcacctacct
    31201 attcaagcaa cagcttgcat gctgctattg ttgaaatctt tgctttagat ggtgcttaca
    31261 tgcgctatac aacaattcaa aattggtctg acaatgtcta caatttggtg accaagcgag
    31321 cgcgtgctct taaggacgca acggttgagt ggattgatgg taatctgggt gctaaaacaa
    31381 ccatgaaata cccttcagtt taccttgatg gtccaggcgc gcgtggcacc atgctctcca
    31441 ttgcctttgc taatactgga cagcaccagg atacaggagc taagatggtg cataatgcgc
    31501 ctcacacctc atcgtctatt gtgtcaaaat ctattgctaa aagtggcggc aaggttgact
    31561 atcgaggtca ggttaccttt aacaagctgt caaaaaaatc cgtctctcat atcgaatgtg
    31621 atacgatctt gatggacgac atttcaaaat cagatactat ccccttcaat gaaattcaca
    31681 actctcaggt agctcttgag catgaagcaa aagtttcaaa gatttcagag gagcagctct
    31741 attacctgat gagtcggggg ctgtcagaga gcgaagctac tgaaatgatt gtcatggggt
    31801 ttgttgagcc ctttaccaag gaattaccaa tggagtatgc tgttgaattg aatcgcttga
    31861 tcgcctatga aatggaagga tcagttggtt agtcaagaag cagctgcatt gaccttatcc
    31921 attagggtga cctgatggat aggcttttta aaagacatag gtactaaccc aagaggttag
    31981 tttttaaata cctaagatat aaaaaaaggc ttcttggcag ctaccaagaa gtctttttaa
    32041 tcagcaatga gcttaacgtc ccatcataaa ggccatcaga gcaagtagta aaacaataag
    32101 gataaaaatg gctaagcaaa ttaggacaag gggacgatga tcatcgacaa attgttctat
    32161 tttttcaaga aatgattgat cagttgtggc ttgtggcaac tgccttttag cagcagctgc
    32221 tgtgctggct ggtttagcaa caagcctttt aagcttgctt cgttttgctt tggtgagtgt
    32281 tttactatct ttaaaggctt tttcagtcaa agcattaatg aatgggtgac ggtaaaattc
    32341 tccattttgg tcagaccaat caccaactcc taggacaact gtaatcagtc tggtatttcc
    32401 tcgttttgct gttacgaccg cattgaaagc agcacttggg ctggatcctg ttttcatacc
    32461 atcaacaccc tctattccaa acttaccatc aggcagagag tggttgtagg aatggaactc
    32521 ttcctcataa ggggttccaa ccatggtgcg gacgacagtt tgattggtaa aatcaagaat
    32581 actaggataa ttggtcaaaa aataataaat taaggttgca aaatcacgtg ctgttgtgat
    32641 attagaagct gttaaatcat atttttctgg gagatagtag ccttgaaagg cttgtgcgat
    32701 tgctccgcta gcatttgaaa aatgcgtatt agtcatgccg agctctttgg ctgttttgtt
    32761 gatccgatca ataaaggctg acgcatcgtt gttggatagg tagttggcaa tcatcactgt
    32821 tgcagcattt gatgacggaa ccactgtcat aatgattaaa tcacgaatag ggtacgcaac
    32881 tcctgcaaca atattattat tgctgatttc gtaaatttta ctaatcgcct gatcagtctc
    32941 tgttgctgta atggtggtat caagtgttac ctttcctttg gccaattcct caaagaggat
    33001 ataaagcgta aacatctttg acatactagc agggtctcta ggcatgtcaa tgttatcctg
    33061 ccataagatc tctgaggtct ttgcgtcaac aacaatggag gcttttggct tattaacctc
    33121 actaacggta tagccagcct tgcgggtaat ttccatgaca tcttcggcgt gaacctgaga
    33181 aatgcctaga aagcacaggc acaccaaaac gaatagtagc aatcttttag tcaattcaaa
    33241 gctccttaat gtaaaaaaat aatgtaagct tattatatca tttcaataat acaaatgaaa
    33301 tatatttttt gaaaatatta agggttaatg agaatgccaa tgactttttg aaaaaagtca
    33361 aataatttgc taagtttccc tttttcagga atgcttttag ctgagacaat agcaacagct
    33421 ggcggtgctg ctagatagcc actgtcaatg agcttaggat cctgatagat aagggtaccg
    33481 acctttttat tttgacgaat tggggccttg agtgctttgt ctttgattcg tagcgagtaa
    33541 gacagctctg tctgatcctt aggccgaaca accgttaagg tttgactagc cttgaccctt
    33601 agtctttgct ttgctgcttg tttaacaatc agtctttcag gcaaaacttg gttttgagca
    33661 acaagctttt ccaaggcata gctatcaaag caataatcaa gcaggcgatt ggtctcaaca
    33721 aagcgagctc gctcatcagt gtcagattga tcagcatgga gaataacaga aataactcgc
    33781 atattatcct gcacagctgt tgtaatcatt gtttgcccgg cttggctggt agtgcctgtt
    33841 ttaaggccat caaccccagc tctgcccatc tcgcgaccgg ctaatagtag attagagcta
    33901 ggcaagtcct tctcacccca tttcaattgg ggctgtgagg agatggtgag aagctcagga
    33961 aagtcttgaa tcagctgctg tgcaatcagt gccagatctc tagctgtcat ctgattttca
    34021 tcatctggct gtgagcctgg atatagatgc ccctttagca tactgttgtt tagccctgaa
    34081 gcattgacaa gaagatagtc tctaatcccc caagccttca gctgtttttt catcatgtct
    34141 acaaatgtag gctctgagcc agcgatatgc tctgctagag ctacagcaga gctattagca
    34201 ctaataatca ggctagattc aacaagctct ttgatagtgt aaggtctttg ctcaaatgct
    34261 gggttgctga tatcaggatc agtggctaat tgcagagcat attcagatag ggttacctga
    34321 ctatcccact ggagccgtcc tgccttaatt tccttcagga ctaggtagac ggttagcagc
    34381 tttgttagag aagcaatggg cgccttttgc tgagcctctt tggcatacag gatttttcca
    34441 gttgtcattt caaccgcaat ggcttgacga ctattaacag agaagtcctc agcaagggag
    34501 gtgtttgtga tcagacacat gagcgcagca agtgtcacaa taagtttttt cataccacca
    34561 ttgtagcaag gaaatagtga tcggtcaaaa ggtcattgag tacctttaaa gaaggctagg
    34621 tcaagactct gagtgagatg acgtccccaa aaatcaagcc tcaaaaaaac cgtctgacat
    34681 caacagacta aagctgtcaa ttcatacggt tttgctgttt gcagagcttt tgtaggcctt
    34741 agagcttgct aggagctctt ttagctacct tcttggagag cctgacacat aatggttaac
    34801 tcttacgggg tagccctaat gaggccctga gtgaggcctt ggcactaatg agtacataag
    34861 gcataaaagc tagttattag aggtattggt taacataacg aacaaaatga ttccaccaga
    34921 cctttaaaaa gaagcttttt ggaatctttt tttgagccac cagctcaacg cttggggctt
    34981 gacctaaata gccttttccg attaagctat gatcattaag tgtggccttt gcgagtgttt
    35041 gtcctttttg gataggcgct actaagggat ttttggtatc gcttacttga aaagtcgttt
    35101 tggacttgtc gtcaagcgct tttatcatag tgagcttctt ttttggcact agctggatct
    35161 tcttttgagg actatctaaa acaggaagcg ctttaagctg atctggttta cccttttcaa
    35221 ggacaacaac ctttttaaaa tgcgtcaaaa catactgcag caattggttt gtcgctgtaa
    35281 agacggccgt atcgttgtcc tgggcatggt cagcattgag gacaactgta ataatacgca
    35341 tattgttttc gacactagtg gctaaaaaag aagagcctcc cttttcagaa tagctaacaa
    35401 aaagcccatc aacaccatca cgatagttag gcattccctt tagcatatag ttgtatgaaa
    35461 aaatctgttg atgattaaac tcagcttgag cctgacttga tagctttaaa acctcaggaa
    35521 attcctttaa aagatggcta gtgacaagag caagatcggc tgcactaaat tgattatcat
    35581 catcaaggct agatcccgga tagatatgct ctcctagtat gtggttgggc agaccactgg
    35641 cattaacgac cttggcacct gtaatgcccc agtctttcaa ttgagcgatc attttatcaa
    35701 caaacttagc ctctgtccct ccaatttttt ctgccagggc aatagcaggg ctattagcat
    35761 tggtgacaat aagagccttt aacagctctt taacagtata ttttctagca tctaagggca
    35821 cattgcttat ggtgtagttg gtggttagtt cgtaagggta gttagagatc gttacggagc
    35881 tatcccattt taactttcct tcttgcacct ctttgtacac caaataagct gttaaaacct
    35941 tgcttagaga agccacagaa acagtcttgt cggcgtcctt ttcgtataga atcttaccgc
    36001 tatcaagctc aacagcaatc gcatgcttgg cgctaatatc ataatgatca gcctgtgctg
    36061 gataggccag acaagatatg gctaatatgg tcaaagctat taaaaccttt ttcatttgaa
    36121 taatccttct agtcgttttt ttaattatac cataattttt caaggagctt gactaaacct
    36181 ctcagagaag agagatcatt atgagaaaat gctggctgtt atgatagcga taacgaactg
    36241 tataaaaata gcaaataatg tatcttaaac gtcatcagat cgtcaacaga aaaaatcttg
    36301 caaaatattc agataatttt gcgatcgcta tttccatcag ctaaaatttg tggtataata
    36361 gctccaatta accaatttca tttatgctga taaatgaaaa ataacgttta ggggtgactt
    36421 ctatgaagaa aagtaaatgg ttggcaacgc tgggtgtcgc ggcgctgtcg gtgtccatcc
    36481 tggcagcctg tggaaacagc tcaagtaaaa gcagtgaatc aaagatttat agctatgtct
    36541 attctagtga tccaagtact ttagactata tcagtacaag taaagcaaca acaaatgaca
    36601 taacaacgaa tgctgttgat gggcttttgg aaaatgacca atatgggaat ttaatcccct
    36661 ctcttgctaa ggattggaag gtctcaaagg acggcttgac ctatacctac acgcttcgtg
    36721 atgggatcaa atggtacaca tctgatggtg aagaatatgc agatgtgaca gctgaggatt
    36781 ttgtggctgg agtaaagcac gcagcagatg ttaactctga tgccctatat atcattcagg
    36841 actctattaa aggcttaaac gattacttga acggtaagac caaggacttt tcaaccgtag
    36901 gtgtcaaagc gcttgacaaa aaaacggttc agtacaccct taatcaacca gaaagcttct
    36961 ggaattcaaa gctaacctat agtatcctag ctccggtaaa tgctgacttc ctaaaatcaa
    37021 agggcaagga ttttggtaag gcaacagatc catcatctat cctgtataat ggtccatttc
    37081 ttattacagc tttgacaagt aaatcctcta tcgagcttgt caaaaacgaa aactattggg
    37141 acgctaagaa tgttcacctt gatggtgttc aattgacctt ttacgatgga caggatcagg
    37201 agtcattgtt tagaaacttt gatgacggag cttactcagc ggcgagatta ttcccaacaa
    37261 caccttctta caaaaccgtt aagaaaaaat atggagatag catcacttac ggacaacaaa
    37321 atgctactct ctactatgcg gcatttaacc taaaccgtac gtcttacaac catactaaga
    37381 agacctcaga tagccaaaaa tcagataccc aaaaggctat cttaaacaag gatttccgtc
    37441 aggctatgac atttgccttt gatagaattg cttatcaggc gcaatcagca ggtgaagatg
    37501 cagctaacaa agcgcttcgt agcacacttg taccaccgac atttgtgcaa attggcgaca
    37561 aagactttgg tgatgttgtt gaggagcact tggtgaccta tggtagccag tgggaaaatg
    37621 taaatctaga tgatgcacag gatggcttgt acaatcctga aaaggcaaaa gcatcatttg
    37681 aaaaagcaaa agcagcccta caagctgagg gtgtacagtt cccaatccat cttgattacc
    37741 caatggatca aactgcaacg gtgctcttac agcaggctcg ctctatgaag cagtcaatcg
    37801 agaaaacatt aggaactgac aatgttgtga ttgatattat tgagcttcag agagatgttt
    37861 atgaaaatat tagttatctc gccgaaactc ctgctcaaaa tgactgggat atttcaacgg
    37921 cttctggctg gggacctgat tatgtcgacc catcgtcata tcttgatatt ttcaacccaa
    37981 cgcttgcgaa ctcacaaaca aaatcaattg gacttgagcc aggtaaggat ttggccattg
    38041 ctagtgcagc tggcttagac gaatttacaa agctagtgac agaggcaggt aagattactg
    38101 atgatctcaa tgcccgctat acgctctatg ctaaggctca agcggcattg acagactctg
    38161 ctatttatat cccgactatc tcacttggtg gaacgccacg tgtaactaaa gtggtaccgt
    38221 tttcaggtgc ctttgcttgg gctggtacta aaaatgactt ttattacaaa tacgtcaagc
    38281 tacaagataa gcctgtaact gctaaacaat atgacaaagc attggccgag tggaaaaaag
    38341 aaaagaaaaa atctaacgaa aaatataata attccctcga gaagcatatt gaaaaataaa
    38401 ttgatgttca ttaagaactt tctcttagag gaggaagttc ttttgaactg ctggggacta
    38461 gaatgaaaaa atacatattt gaacgcatat tgaggtcgct tgtttcaatc ctgctggtaa
    38521 ccgcactaac ctatactatt gtctttacct tagtgccaaa aagcttgatt tttaagcaag
    38581 accctaatta caataaaatg gtgacaacac ctgataagaa aaccaattat ctaaatactg
    38641 tttttgaaaa tatgggctat atttcctatt acagcagtaa agaactgcag aataaggctt
    38701 caaagcttga tcctgctgta acaactgcac caaccaaggc caatgaaaaa atatatcaaa
    38761 aatatattgc ttctgtcggt aatggttgga agcttgggcg ctttacagaa agtaagggat
    38821 tttatgccgt tagagagatt ccaatctatg agcgcgtgtg gaatttcttt agccatttgg
    38881 ttgtgattga tcacccatgg aaaatcaagg atccaaaaaa tccaaatcta gagcgttatg
    38941 tgcgaccaga aattgaccct gctgttggtc cagccttagt tggctctggt actaagcaca
    39001 aatacttgat ttacttcaac aagcaatttc catttatcca tcaaaatatc gtaacttttg
    39061 atttgggagt gtcctatcca acctatgcca atattccagt tgttcaggtt atcactcaag
    39121 gacaaggaag aacacttcaa aaagaggtca ccttcccaac aggcaaaaca aagctgtctt
    39181 caattgatat ttactctcga acctataaaa caccaagctc tttagatagc aaggatattg
    39241 ccaattttgg taagggtgat gcttatacca atacacaaaa taactatgca gagccatcta
    39301 tgattgcaaa ttcctttaag attggtattg tcggtgtctt gttgtcctat ctttttggtt
    39361 tgccaattgg tatgctgatg gcttattata agaatggctg gtttgaccgc ttttcaacgg
    39421 ctgccacaac ctttatgtta gccctgccca gcattgcgct tatctatatt gttcgatttg
    39481 tcggttctta tttgggcttg ccagatacct ttccgctact aggagcagga gatgttaggt
    39541 cttatgtgct acctgctctt atattaggaa ttcttggtac accaagtaca gtagtttggt
    39601 tccggcgcta tattgtggac ctgcaaggca gtgattttgt tcgctttgca cgagcaaagg
    39661 ggctttcaga attcgagatt tcaaaaaatc atctctttaa gcaggctatg gtgcctattg
    39721 ttaacggtat tccacaggcc attgtcggaa caattgctgg tgcaaccttg acagagacgg
    39781 tgtttgcttt cccaggaatg ggtaaaatgc tgattgattc cataaaagct gctaataact
    39841 ctatggttgt tggtcttgtc tttatttttg ctgttttatc aatattagcc ttgctagtag
    39901 gtgatattct tatgacgatt ttagatccac gtattaaatt atcaggtaaa ggaggtaagt
    39961 aatggcagca attgacaaaa ataaattcac ctttgttgaa ttggatagct atgcatcaga
    40021 agtcattgat gctcctgctt actcttattg gaaatctgtc tttaggcaat tcttctcgcg
    40081 taaatcaacc gttgtgatgc tggttatttt aatcgctatt attttgatga gcttcatcta
    40141 ccctatgttt gccaactatg actttggtga cgtgagcaat attaatgatt tttcaaagcg
    40201 ttatatagca cctaatgcag agtattggtt tggtacggat caaaatggtc aatcgctctt
    40261 tgatggtgtt tggtatggtg ctagaaattc aatcttaatt tcagttattg caaccatcat
    40321 caatatgatt atcggagtca ttgtcggtgg tatttggggt gtttccaaag cagttgataa
    40381 ggtaatgatt gaggtgtata atatcatctc taacctgccg caaatgctcg ttatcattgt
    40441 gttgacttat tctatcggag caggcttttg gaacttgatt tttgcttttt gtgtgacagg
    40501 ctggattgga attgcttatt cgattcgtgt acaaattttg cgttatcgtg atttagaata
    40561 caatttagca agtcagacct taggaacacc gacccataag attgtcatta aaaacctttt
    40621 gcctcaattg gtttcagtga tcgtttcgat ggtttccttg ctattgccgt cctatatttc
    40681 atcagaggcc ttcttatcct tctttggctt gggattacca atcacagaac caagcttggg
    40741 tcgattgatt tcaaattatt caaacaattt aacaacgaat gcctatttat tctggattcc
    40801 attgacaact cttattcttg tttccctacc tttatacatt gtaggacaaa acttagcaga
    40861 tgctagtgat ccaaggacgc atagatagga gaagtcatga ctgaaaaaca agaaattata
    40921 ttaagtgcta aaaatattgt tgtagagttt gatgtgcgtg atcgtgtact gaccgctatt
    40981 cgtgatgttt ctcttgattt gtataaggga gaggtattgg ctgttgttgg tgagtcaggc
    41041 tctggcaagt ctgttttaac taagacattt acaggaatgc tggaggcaaa tggacgtgtt
    41101 gcttcaggga cgataaccta tgcaggtcaa gaactaacag agcttaaaaa tcataaggac
    41161 tgggaagcta ttcgcggctc taaaattgcc actatctttc aggacccaat gactagtcta
    41221 gatccgattc aaacgattgg cagccagatt actgaggtta ttgttaagca tcagaaaaaa
    41281 tctagatcag aggctaaggc tttagcaatc gactatatga caagggtcgg tattcctgag
    41341 ccagaaaagc gttttggaga gtatcctttc caatattctg gcggtatgag acagcgtatt
    41401 gttattgcca ttgccctagc ttgtaagcca gatattctga tctgtgatga gccgacaaca
    41461 gctcttgacg ttaccatcca ggctcagatt attgacctat taaagacgct tcaaaaagag
    41521 tatcacttca ccattatctt tatcacgcat gacctaggag tggttgcaag tattgctgac
    41581 aaggttgctg ttatgtacgc aggggagatt attgaatacg gaaaggttga ggaaatcttc
    41641 tatgatcctc gtcaccccta cacatggagc ttattatcta gcctaccgca attggcagat
    41701 gaaaagggcg ttctgttttc aattccaggg acacctccgt ccttgtataa gccgattgtt
    41761 ggggatgcct ttgcgccacg ctctcagtat gctatggcca ttgattttga agaaacagtt
    41821 cctcgtttta cgatcagtga cacgcattgg gcaaaaactt ggctgttaca tccagatgca
    41881 cctaaggttc aaaagccggc tgttatccaa gatttgcatc aaaaaatatt aaaaaaaatg
    41941 tcacgccagg aggaaggaaa tgtctgaaaa attagttgaa gtaaaagacc tggagatttc
    42001 ctttggagag ggaaagaaaa agtttgttgc cgttaaaaat gccaatttct ttatcaataa
    42061 aggagaaacc ttttctcttg ttggagagtc aggcagtgga aagacaacaa tcggtcgtgc
    42121 catcattggt ttaaatgaaa caagctcagg cgaaatccgc tatgacggta agattattaa
    42181 tggtaaaaaa tcaaaatctg aagctaatga actgattaga aaaatccaaa tgatttttca
    42241 ggatccagca gccagcctga atgagcgtgc aacggttgat tatatcatct cagaaggcct
    42301 ttataatttt aacctattca aaacagaaga cgaacgtaaa gaaaaaatta aacagatgat
    42361 gtcagaggtg ggcttgcttg cagagcacct gacacgctac cctcatgagt tttcaggtgg
    42421 gcagcgtcag cgtataggta ttgcaagagc gcttgtaatg gatccggagt ttgttattgc
    42481 tgatgagccg atttcagctc ttgatgtatc tgttcgtgct caggtcttga acctgttgaa
    42541 gaaaatacag gctgaaaaag gcttgaccta tttattcatt gctcatgatt tatcagttgt
    42601 gcgttttatt tcagatcgta ttgctgttat tcacaaagga gtaattgttg aagtcgccga
    42661 aacagaagag ctttttgtta atcctgttca cccttatacc aaatctctgc tgtcagcggt
    42721 accaattcca gatcccattt tagagcgtca aaagaaattg gtggtttatc atccagagca
    42781 gcatgattat tctgttgaca agccatcaat ggtggaaatc aaaccaaatc acttcgtctg
    42841 ggctaaccag gcagaagcgg agcgttaccg caaagagctt taagattagt tatcatcaca
    42901 taacagaatt tagccccagc tagattctgt ttttgccttc cttgggtagt cttttttttg
    42961 ttctgacaag gatagaaata tccagcattt tccatctatt tacaaaaaaa cgctaaattc
    43021 tcagagtaag ttctaggtca ctaggaagtg gcatttagta tgagaaaagc gcataaaatc
    43081 gcagaattta ttctcagagt aagttctgtc ttttgttaaa aacctgttaa cagaggagtt
    43141 tatagttcaa aaatagggta aaaaagagta cactaaagct actggctctg agatgtctca
    43201 aagtaagttc taggtaactg gaaattcgga tgggacaagt tcctttctaa tttttgaggt
    43261 ttattagttt agtattaaga gttacttgtc caacaacctt ggtgactgta ggacatcttc
    43321 agggtcgatt ttagtgattc caagtaaaat agcgatatct ttcccataag tgaatgtaaa
    43381 gagctcataa gcagattttc cgtttagagc atgtcgcctg accccgttca cgtgagaaca
    43441 gacgagattg atgtcgtctt gagttaagtt gtcaaaactt gttcctttag ggagaatgtc
    43501 tcttagaagg gtgtgattct tctcaattct cgctttctgg tcagagcggt tagggtcaca
    43561 gaaaaagagt ttaagctcgc ctctgatgtc catttcgata tcatcaactc tagcgaattc
    43621 accaccgttg tcagttagaa tgacaggaga gaattcgtga aaatctctat ctgctttaaa
    43681 gaagtcgttc ttgatagcgt agaggtgttt agcgacttct gtagcggtct tattatcaag
    43741 aagtctggca aagatgaagt tacataaaga gacgttgaag gtgagcagta ccttaccgcc
    43801 aattcgtcca atgactgtat ctatttcaat ccaagaagtt aggtcttctt tagcttgatg
    43861 tttctggaaa tcctcgtagg ttcttccgac cttgtctttc ttaggaatcg gaggtaactg
    43921 actggttcta cgctttctaa acttaacgac acgagggaag tcaataggtc tagcagagag
    43981 atagcctttt tctaagtatc ggtaactact agctctagag ggagttaggt tattggagga
    44041 aatgatgtga ttgaggtgct gtcctttctt gatggcagag gagacgatat tatccatcgt
    44101 gtaaaattct tccttgttaa gagcgacccc agttctagct tcagaaagct gagtttcata
    44161 attgagctga gcttttttaa gaagtgggca ggtattacaa ttggattgta cggtagtttc
    44221 tttgataaag agatttcgac gcacttcttt agagatggta gaagggtctt taccgagttt
    44281 agctgcaatg gcagagaaag gtttacgttg ttcaattccc atttgaatgt ctgtacggtc
    44341 tgagagagtt aattgtttgt gtttcatggt aggttaccga cttgtcccaa agtaagttct
    44401 accttatttt tctgtctcag tctaatttct agttttcaac gacacctgga acttactttg
    44461 agatttaacc tacaaaaaaa aacctgtcaa aacct
//
LOCUS       DARYSY010000015        42494 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYSY010000015 DARYSY010000000
VERSION     DARYSY010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42494
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(20..418)
                     /gene="spx"
                     /locus_tag="TVR04_000686"
     CDS             complement(20..418)
                     /gene="spx"
                     /locus_tag="TVR04_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1269393.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            complement(794..1930)
                     /gene="recA"
                     /locus_tag="TVR04_000687"
     CDS             complement(794..1930)
                     /gene="recA"
                     /locus_tag="TVR04_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1269394.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            complement(2024..3295)
                     /locus_tag="TVR04_000688"
     CDS             complement(2024..3295)
                     /locus_tag="TVR04_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1269395.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLRKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLVELQRHGVV
                     SSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIATLYAFNMVRKTLLKSENLL"
     gene            complement(3981..4271)
                     /locus_tag="TVR04_000689"
     CDS             complement(3981..4271)
                     /locus_tag="TVR04_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269396.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            complement(4265..4837)
                     /locus_tag="TVR04_000690"
     CDS             complement(4265..4837)
                     /locus_tag="TVR04_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1269397.1"
                     /translation="MKRRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTPRKYFK
                     AGWQLYGNYCGPGHNGNNFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            5134..5979
                     /locus_tag="TVR04_000691"
     CDS             5134..5979
                     /locus_tag="TVR04_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1269398.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVDVMISLRKKGVKNNQDLQELAYKIWNSLAKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            complement(6416..6967)
                     /locus_tag="TVR04_000692"
     CDS             complement(6416..6967)
                     /locus_tag="TVR04_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1269399.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDIATVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(6977..7573)
                     /gene="ruvA"
                     /locus_tag="TVR04_000693"
     CDS             complement(6977..7573)
                     /gene="ruvA"
                     /locus_tag="TVR04_000693"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1269400.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDIKYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            complement(7575..8798)
                     /locus_tag="TVR04_000694"
     CDS             complement(7575..8798)
                     /locus_tag="TVR04_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1269401.1"
                     /translation="MREFFQLPKQIQVRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVVSTLGWLLTILANAPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTLINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACA
                     GLYVIVLSAKMKKKV"
     gene            complement(8809..10791)
                     /gene="mutL"
                     /locus_tag="TVR04_000695"
     CDS             complement(8809..10791)
                     /gene="mutL"
                     /locus_tag="TVR04_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1269402.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELSHVVDVVNRLSLAHPEIAFTLISDGKHLTQTSGTGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDLQKNDFFTKETVVSEDSPQGFNHETLV
                     DNDVKQVDNLQMTKTESEAAAPSVKYASRPDPMLSDSEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            complement(10938..13493)
                     /gene="mutS"
                     /locus_tag="TVR04_000696"
     CDS             complement(10938..13493)
                     /gene="mutS"
                     /locus_tag="TVR04_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1269403.1"
                     /translation="MAKANVSPGMQQYLDIKKNYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQMNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRTWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESRIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADAVLTKLEAQSQAREFVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            complement(13480..13827)
                     /locus_tag="TVR04_000697"
     CDS             complement(13480..13827)
                     /locus_tag="TVR04_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1269404.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQLLQRTDYNQKAYQMKR
                     HQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGTI
                     EDELNKEFNDGKG"
     gene            complement(13829..14266)
                     /gene="argR"
                     /locus_tag="TVR04_000698"
     CDS             complement(13829..14266)
                     /gene="argR"
                     /locus_tag="TVR04_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1269405.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            14549..16240
                     /locus_tag="TVR04_000699"
     CDS             14549..16240
                     /locus_tag="TVR04_000699"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1269406.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAEADPSIDEEAREWFRRLE
                     EGDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEILELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDNPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            complement(16288..17682)
                     /locus_tag="TVR04_000700"
     CDS             complement(16288..17682)
                     /locus_tag="TVR04_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1269407.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKAQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMEHRLTRMKEVNRPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSKLAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLELDQTAVEFISRQSSQDRVTILNYLAMMSIDYDKANQKVAILSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKNHHLTAYHFED"
     gene            complement(17854..18768)
                     /locus_tag="TVR04_000701"
     CDS             complement(17854..18768)
                     /locus_tag="TVR04_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1269408.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            complement(18912..19793)
                     /locus_tag="TVR04_000702"
     CDS             complement(18912..19793)
                     /locus_tag="TVR04_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1269409.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVMVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            complement(19809..20756)
                     /locus_tag="TVR04_000703"
     CDS             complement(19809..20756)
                     /locus_tag="TVR04_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1269410.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVINIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            complement(20749..22497)
                     /gene="aspS"
                     /locus_tag="TVR04_000704"
     CDS             complement(20749..22497)
                     /gene="aspS"
                     /locus_tag="TVR04_000704"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1269411.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQVNDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVESKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            complement(22654..23394)
                     /locus_tag="TVR04_000705"
     CDS             complement(22654..23394)
                     /locus_tag="TVR04_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269412.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMTLITQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVIKLVVLLLWLVATALLSVNWLNRQS"
     gene            complement(23381..24301)
                     /locus_tag="TVR04_000706"
     CDS             complement(23381..24301)
                     /locus_tag="TVR04_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269413.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGRIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVRNLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            complement(24312..25430)
                     /locus_tag="TVR04_000707"
     CDS             complement(24312..25430)
                     /locus_tag="TVR04_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000675233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEL1269414.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDPTGELWEL
                     VTRLNGTELNIIFKEMKELFPNITLSAIEYGIDLLANEGLIEEFGQNDSVDDRYMSNV
                     NYFRRYLDSYEDSLAVQKKINNSSILLLGLGGGGSNILTLLAGLGPKKLTIVDYDRVE
                     RNNLGRQMLYKESDIGELKTVVAKREFEKMNSSVKLTTIDKKINSTTDVLDLLVDIDL
                     VICAIDEPPFVAQRRVNEAIIKAGVPCVFGGSQVSRGRVYSVVPGETGCFDCLNIHYT
                     KTSPNFIDQFVGFQKINFNPPTVAYGPAIFQLSGAIVDEAIRILTNFCIPMSKSTQFE
                     INYETGASFTHKPWPRFKECPTCGHGNSNDWEIFSHYG"
     gene            25672..26388
                     /locus_tag="TVR04_000708"
     CDS             25672..26388
                     /locus_tag="TVR04_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269415.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPYQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSHHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            26378..27670
                     /locus_tag="TVR04_000709"
     CDS             26378..27670
                     /locus_tag="TVR04_000709"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1269416.1"
                     /translation="MVINAIFHLYTSVVNIVIVNYFFRQKNGQLATPKNIGYLSFLVF
                     IECCTHFFVSESYASLITLTCSLLTSLIISSSYHYSMKQCIFWSVTLQSIGILLEASL
                     GIVLISLNYQISSISGTFLFINLLTISSSILIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISEQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(27875..29155)
                     /locus_tag="TVR04_000710"
     CDS             complement(27875..29155)
                     /locus_tag="TVR04_000710"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1269417.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEALAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGADANVAALALTQAIRCQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKA
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(29215..30045)
                     /locus_tag="TVR04_000711"
     CDS             complement(29215..30045)
                     /locus_tag="TVR04_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269418.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPTIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSSRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            30315..30497
                     /gene="rpmF"
                     /locus_tag="TVR04_000712"
     CDS             30315..30497
                     /gene="rpmF"
                     /locus_tag="TVR04_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1269419.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANAAE"
     gene            30513..30662
                     /gene="rpmG"
                     /locus_tag="TVR04_000713"
     CDS             30513..30662
                     /gene="rpmG"
                     /locus_tag="TVR04_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1269420.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(30767..31516)
                     /locus_tag="TVR04_000714"
     CDS             complement(30767..31516)
                     /locus_tag="TVR04_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1269421.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(31521..32165)
                     /locus_tag="TVR04_000715"
     CDS             complement(31521..32165)
                     /locus_tag="TVR04_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269422.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEAVFDALQNDHRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            32580..34421
                     /locus_tag="TVR04_000716"
     CDS             32580..34421
                     /locus_tag="TVR04_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269423.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLMGTGLLGNKVVYGDVSSDAD
                     SIKKVLTSGENLKESLQKVTDPKTLFGLFAILSGDFGLDNESDNLVITTLSDLVSDFS
                     KSGNNSNNRKAVIEEIKRRVLSLESAKKNEQIAKKEAEKNKKDLETEKLQNGILSRDL
                     NASREAHRVLSKLFDDLEEKFAKAKIDKKQAEEQAKKAITAKEKAEKDVKTAQQESEQ
                     AKKAADQAETDKKKAQDEAKNAKLDSQRAQEEANKLRGEAEKAKQEAEKSKKDLETQK
                     EKLEQEIKEAQESKKEAEQKLKKLQESSMKNDTAAQQLLKEKEELTTKLQDLQKQAEE
                     KTTEIEKLKQELENTKNNSGQLGQQEQKLQEQLNKVQEELKQKEMELEKAKEQLKQEQ
                     KPHEGDDTSKAKIAELEQQVQTLTKEKENLSSTLESTKAQLTETQAKLSEAQKQLTAT
                     QEKLTTLEAEKVALQHQVETISKQLSEARDLSEKEKAALQEQINKLKAEIEQKTKEIE
                     ALKQGMHSHQGQEKPKDPKTPEKKDQPQTPVPWTALTPAKPIDTTKAPKSSAPSPQTG
                     AATPKKQLPATGDTATPSFFTAAAMAVLASVGVLSLSPRRKKEQNNR"
     gene            34651..36453
                     /locus_tag="TVR04_000717"
     CDS             34651..36453
                     /locus_tag="TVR04_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1269424.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLVVGDKILEIDHKSSRDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYMFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIIAKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNY"
     gene            36431..37030
                     /locus_tag="TVR04_000718"
     CDS             36431..37030
                     /locus_tag="TVR04_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269425.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQKQESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            37138..38064
                     /locus_tag="TVR04_000719"
     CDS             37138..38064
                     /locus_tag="TVR04_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1269426.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAEGYLKEQYEVCEGFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFTVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            38057..38833
                     /locus_tag="TVR04_000720"
     CDS             38057..38833
                     /locus_tag="TVR04_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1269427.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGLPGRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPM
                     SADGHRPVSERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPID
                     EAVTQAEEQIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            38842..39513
                     /locus_tag="TVR04_000721"
     CDS             38842..39513
                     /locus_tag="TVR04_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269428.1"
                     /translation="MISFKNISKTYQVGDQEVKALDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            39530..41803
                     /locus_tag="TVR04_000722"
     CDS             39530..41803
                     /locus_tag="TVR04_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269429.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISASHLPTVWVQATNLTKQDIEKIEALNQVSRVKPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDIRDDIENILGNKLISYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALFGLLISPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLMVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVY"
     gene            42275..>42494
                     /locus_tag="TVR04_000723"
     CDS             42275..>42494
                     /locus_tag="TVR04_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1269430.1"
                     /translation="MITKKQRKQKRHTTIRRLCHQALAATLITGSLMGTGLVGNKVVY
                     GDVNSEIEKIKNVLKQESDNSSTLTETLK"
BASE COUNT        13506 a         9153 c         7483 g        12352 t
ORIGIN      
        1 gcgggtcagt tcgagctttt tataaagcag cgcgtaaacg cgcttctgca ttttcaatat
       61 tacgaataga acgaggtaaa aaggcacgaa tatcgtcttc cttgtagccc acctgaagac
      121 gcttatcatc aataagaatc ggacttttta aaatacgggg attgtcctga atcaaatcaa
      181 taacctcatt tacgcttaac tcgtcaatat cacaatttaa ggctttggca taacgatttt
      241 tagaagagac aatactctcc acaccgtttt cagtctttga taaaatagct aaaatttctt
      301 ctcttgaaag aggttctttt cctaaattct gttctttata tgggagctta tgggcattca
      361 gccaggtttt ggccttttta cagctcgtac aacttgaaat cgtgtaaatt tttatcatgt
      421 tgttctcact ttctatctcg tgatacttct attgtagcat agtttttttc taatcaatat
      481 cggtctttgg acctattttt tagttttctt ttatgatccc tttaaccaat gtcaaaatcc
      541 tatattgagc tagttgcaag caagcttact atgccactat cttgtctgta ggaagcccct
      601 tttttctagg gcttttatag cttaacagtt aatccctaaa gaaaacataa actcagctga
      661 caaatcgtcc aaacgtccag cctagctcct gagcagatca atacagagct tgatcaaaca
      721 caagctaaaa agggcttgac gatcgctgtt aagccctttt tagcaccttt atctgaaaat
      781 ctaatactaa gcactaatcc tcaatttcaa tggcatcgtc tagctctaaa accaactcat
      841 ctgctttggc tgcaactgta tctgcagctg cactttcctc agtatcttca agcaagccaa
      901 atttaacacg caccttatgg tcaatctcat caaacagctc tgggtgatca gccaaatatc
      961 tcttggcatt ttcagagccc tgaccaattt tttcaccgtt ataagagaac caagcaccag
     1021 ccttttgaat aatgtctaaa tctgaagcaa ttttaatcag ctcacctgta cgtgagatgc
     1081 cttctccata catgatttca acctcagcca ccttaaatgg cggagcaacc ttattcttaa
     1141 caaccttaat cttggtttcc ttaccaatac tactgtcttt ttgatctcca gttcctttta
     1201 tttgtgttgt tccacgaaca tccagacgga cagaggcata gaatttcaaa gcacgaccac
     1261 ctggtgtcgt ctctggatta ccaaacataa cccctacctt ttcacgcagc tggttaataa
     1321 agatcgcaat tgtcttggtt ttattgattg aggctgaaag cttacgcatt gcctgactca
     1381 tcatacgagc ctgcagacca acgtggttat caccaatatc accatcaatc tcagcacgag
     1441 gcactaaagc tgcaacagag tcaacgacaa ccaaatcaac agcaccagaa tcaatcaatt
     1501 tacctgctat ctcaagtcct tgctcaccag aatccggctg tgacaaaagc agctcatcaa
     1561 tattaacacc tagcgccgca gcataggcag gatccaaggc atgctccgca tcaatgaagg
     1621 ctgcaatacc accttctttt tgagcctgcg ctactgcatg cagggcaact gttgttttac
     1681 cagaagactc tggtccatag atttcaataa tacgcccttt gggatagcca cctgctccaa
     1741 gcgcaatgtc taaagcaaga ctgcctgagc tcatcacctg aaccttttgc tctgcacgct
     1801 caccaaggcg cataaccgca cccttaccaa aatccttttc aatgttcttt aacgcatcat
     1861 caagtgcctt acgacgttca tcaccaaatt ttttggtgat ttcttcattt tttttaactt
     1921 tttttgccaa tattttctcc tctattcagg ctaattagta agcaataaac agtataacct
     1981 cacatctgtc tagctactaa tttcctaaaa tacactatct taattatagc aaattctctg
     2041 attttaataa agttttacga accatattaa aagcgtacag agtagcaatg taccgcacgt
     2101 ccaaacggct gcgacctcct atgacaactt taagagattc taccttattc ttagtggcaa
     2161 ggccaatgaa aactgttcct gctggctgct cctcgagttc ctctggacca gcaacacctg
     2221 ttagaccaat accgatatct gaatcggtca agcaacgtgc ctgcgcagcc atttgctcag
     2281 ctgtaaaaga gctcacaaca ccatgccttt ggagctcaac caatggaata ccaagcattc
     2341 ttgctttttc ttcaatgctg taggtgataa agccaccgtt aaacacctgt gaagctcccg
     2401 caaaatcagt tagctgggct tgaaacagtc ctgctgtcaa gctttcagct gctgttatcg
     2461 tcttgccact tcgcttcaat agctcaaagg tctcacgtgc caaggaatta tcctccccat
     2521 agccataaag caaacgccgt aagggttgat tatctacagt tcttatggat aagagctgcg
     2581 cctctagtcg attcagcctt tcatcagcta atgcttggtt gtcagccttt gtggatagtc
     2641 gcagtgttac ctcgccggtc tttgcataag gagcaatggt gggatctgtt tgatgcttaa
     2701 tcaaatcctc cagagcagtc accagttgac tttcaccaat gccaaaaaaa cgcagcactc
     2761 ttgagtatag actggcgtga ctagctgaaa gaaggggcac cagctcattt tttaccatag
     2821 gctttagctc acttggaggc cctggtaaga caacataggt taccctatct acagttatta
     2881 acccacctac tgcaagtcct gtttgatttt gcaaagcaac agagccttca atcagctgcg
     2941 cctgacgttg attatttggt gtcctagcag cttgcttacg atgtgcaaaa aaagcatcta
     3001 atttttgacc tgcctgctca tcaaagacca aagcttttct tagatactta gctaaggtct
     3061 gcttcgttag atcatcatct gttggaccaa gaccaccaca taaaatcact aaatcacttc
     3121 gctggctagc aatatcaata acagaaagca aacgctcttc attatctcct acagctgttt
     3181 gaaaataaac atcaatacca agctccgcca ttttttctga taaaaattga gcattggtat
     3241 tcacaatctg accagtcaga atctcggttc ccaccgcaat gagttcagct ttcattttcc
     3301 cacctactta tctattcgac attcaatctc attttaacaa aaaaagaatc atccatgaag
     3361 cattgaaata attttagatg aattaatggt tttcaatgat aatcaaataa agacttatgt
     3421 tgaaatagta acaatcagaa taacttgttt aaattttcta aaatttattt catgtgacaa
     3481 tcccgctatc tctctaatta tcaacacacc gataaatagg tattagaagc taagcagtaa
     3541 tcttcaaaag attttagata attgttagct taaaattgca cttattcaca acaatttcgg
     3601 aataaaaatc aacctcaaaa aacaaaaagc gagcaatgat aggacttccg aatatcagat
     3661 cactaacaaa gtcgcttttt tacttttata cttgtgacaa tttagattga ttacaacgtt
     3721 tttttagtta cattttattc aaatgaacca agaatgagaa agcaatgctc taaggatttt
     3781 gcataaataa caactaatca atccaatatt aacaaggaat accctgaagc agcaattccc
     3841 atgcctagaa tagtcttttt aacattgtca acagtgaaca aatgataaag agatactcca
     3901 aagcatctga gaagtaacag gaagccttac agaaaaacag cctgttcctc atcttcaaaa
     3961 caccataaac agtttaatcg ttaattcccc aaaagtccag gtaatagata gaaagctaag
     4021 aaaagattaa tccaaaaagc agcacagcat agtaaaccaa aaattccaag aacaattttt
     4081 ctagaaataa tggccattat catcgcaact actcctagta cgataaatac ctgtttcata
     4141 atcagtggat agagtaatac accagccaca gtagtatccc atcgtacaaa aaacatccca
     4201 atccagatca caacaataag gaatacataa tacatgtagt atcgattgat aatatttttt
     4261 aaggttaaca tccaatagca cctaccgttt caaaatatac tctaatagca tcagcaaccc
     4321 ccaaggcatg agctggcatc caccgtcgat atactttaat gtaatttact aactgacgat
     4381 tgcattcaca atttgcacca atcccagctc cccatcgata acaactgtca tgattttgac
     4441 agccttgatc taaaacatca ataacaggta aagtaaaatt atttccgtta tggccaggtc
     4501 cacaataatt accataaagt tgccatcctg ccttgaaata ctttcgaggg gtaaacgttt
     4561 gttgtgaata gtcctcacta attgtctcaa caaggaatcc catatctatt acaccatcag
     4621 aaaccttatc ttgaatagcc ttgtcataat caaaatacaa tctatcacca ctttggacca
     4681 aatatttttt caacagttct ccattgtaaa aactcacatc actatctgtt gccatagttg
     4741 cacttgcagg tgcagtatct gcagctaaaa cttcatttcc taaactaaat cccaaaatac
     4801 caaaagcaac taatataaat gctaaacgtc tcttcatatg cttttctcct cttaaaatgt
     4861 ctttcactaa gctacttgta ttttactctt tgattaatct agatagtcta atggcaacaa
     4921 cataacagta atcagttaag ttctatggtc cccaaggcca ccatggaaaa ttaccctcat
     4981 ttacaataaa tgtcaatagt gctgcaagta ataatacaac ctttagatgt ctcctcataa
     5041 attttcctcc tttactcttt ctaaatgcta ttataaaata ttattgtaga ttttattttt
     5101 ttgtagcatt tagtaacatt ttagaggtgt tttatgcgtt gggattacgg taaaatttat
     5161 caagctatac gaaaatctaa gggattaaca caagaaaaga tctgtggaga ctttttagct
     5221 cgttctacac tagctcgtat tgaaagcgga caagtcattc ctaaatttga tacaatgatt
     5281 tttttattaa accaactcaa tatgacactg gaagagttta gatatgtctg caacacttat
     5341 catcctagca caaggcagga cattttaaac caattttata atcaggtatc agctgtaaat
     5401 attactgaat tagaaaaatt acgccaaaaa tgcttcaatt accttaaaaa taaaaatgat
     5461 attcccattt cttatatttt agatagtgtc gacgtcatga taagtcttag gaaaaaaggc
     5521 gttaaaaaca atcaagattt acaagagcta gcttataaaa tctggaattc cctcgcaaaa
     5581 caagatactt ggtatgagaa agatttacag ttactacata ccattctttt tcactttcct
     5641 atcgaaataa ttgaaaatat cagtcaaaaa attttagata gcctagcaaa atataaagat
     5701 taccgcaata tcaaatcgtc tgaatatgct ttactaacca atctttcaac catttacctc
     5761 tatcacaacc tcaaaaagga gtgcgaagaa attaccttac taacaatcaa attagctaga
     5821 cagcttaaac gttacgatag cttaggtttt tcccaagttc gtctcggtat ttgtcgtaat
     5881 gatgatcacc taattaataa aggcttacaa ttactgcagt tgacagaaga aactgaactt
     5941 ctagaaacct tgcaacatga actaaaaaac taccgctaag aaatttttaa gcggtagctt
     6001 ttattataga ctataaatga aaaactagct gataagaaaa aaatagaaac caagggggta
     6061 acaccaatcg taccgatact ctgttataac ttttagagcc acaatcacat gcaccaaaat
     6121 aagttataga aagaagcacc agccaacagc aacacaatcg ttgaagcagt ccaatatatc
     6181 tgcctgatca aactatatct tactttcaat agcagtaaca ggctaaaacc ttaaacccat
     6241 tagaagctta caacattcgc tacagggtaa ataaggggat tcatcatcta tccttaaagt
     6301 acggagcaaa aacatagctc ttatacatca tcctataagc aatcaagatt gggctgtttt
     6361 tatcaagctc tctttgatag gctcatgaaa caccattcca aagaggcgat taattctacc
     6421 taaactcaca gttctcttca tggtcattga ccaatcctgc tgcctgcata aaggaataaa
     6481 cagttgttgg tcctagccac ttaaagccac gttttttcaa gtccttagat agcttgagag
     6541 atagggctgt ttgagcgggc gctgggttgt catcgttgac aagcctgtca attggctgac
     6601 ctcctacaaa gttccaaaga tagctggaaa agctaccata ctcttgttgg atgcgctgga
     6661 ctgccgctgc attgttgaca gtggctatta gctttggctt gtgtcggata attgctgcat
     6721 tttgcaaggc agcagccatt tcctgctcac taaagcttgc cacagttgca atatcataat
     6781 gatgaaaaac gcttctgaag gctggacgtt ttttcaaaac agttaaccaa gataagcctg
     6841 actgatagct ttcaagacaa agcagctcaa aaagagcgcg atcatcatag acaggccttc
     6901 cccactccaa gtcatggtaa tcacagtaaa gcttattatc ttgtggtacc catgcgcaac
     6961 gtttcatatg aagcacctag cctttcatta gcattttcag agctgatttg atatactgct
     7021 cagctgtctc acttgttccc tcaaagaagg cacgaatttt ctttagctct gtcgccttat
     7081 atccaagggc taatagggct tcgacagcct catcaagctg ttcattcccc tgttgcttgg
     7141 ctttaggggg cttactgctt tcctccttag gtgcttcaac gaacttacct gctaaatcaa
     7201 gcaccatttg ctgagctgtt ttttttccga ttttagggaa cctcatcaaa tatttaatat
     7261 cactattatc aatggcattg acgagtcctc tattatcatc tacagctaca atagctaggg
     7321 cagtcgtcgg tccaatacct gataccgaaa tcaatttcaa aaaaacgtcc ttttcttcct
     7381 cactgtgaaa accaaacagc agctgagcat cttctctgat cacctgatga agatagatcg
     7441 ttacctgctg attgacacag tctgtaaagc tataaggatt ggcaacagtt atcatatagc
     7501 ctaaaccatt tgcttctacc acaatatatt ttgcagtaat ttttgttagc tgacctttaa
     7561 tataatcgta catactacac ctttttcttc attttcgcgg ataaaacaat cacataaagt
     7621 cctgcacagg caatcaaaac aaatgctagc tgaacaccag cctgtcctgt aaaatgacta
     7681 agagaaacca gcaaacctgc tagaatagct cccaaaggct gggccatcga gacaaagcct
     7741 gtgtaggagc caattttaga ctgatccatc atttctgctc ttaacacttg attggcaggg
     7801 acatttagca tttcaccaat ggtaaacacc acaactgaac accaaatagc aaaaaagccc
     7861 gtaaatgtaa atgacaacag cataccaaag gcaaaaataa ccgatccgat caccagctgt
     7921 ggtaataatc tccaccttgc tgtcaagcga ttaataagtg tcatcaacag cacaatcagc
     7981 aaggtattgg taaagaccat cagtgacagc atttttgagc tagtcagatg aataccgagc
     8041 acatcagtct cttcaaaata cagcttaagg tgaaccggaa cgtaattatc catttgcaac
     8101 caaatactgc taaataaaat cgtccctata gtaaataaca caaaagcgcg atccttaaag
     8161 acttgccggt agttagcaaa acctgctaga ataccaatac catgctcaaa gcggtaatgc
     8221 tcaggcctcg tttcaccaaa ataacgatag gcaataccaa agcagacgat attaataatc
     8281 agtaaagcaa tcaacagttc taagaaatac cgatcataaa aaagtcctga aatacctgca
     8341 ccaagcataa tggctatatt aataaaccag taattaatgg tataaacaaa gcgacgattg
     8401 ctatcatctg ttaaatcaat cagcatagcc tcataggcag gagcgtaaaa gctggaagca
     8461 agctcaacca gcaaaattcc cacaaaggtc aaccaaggaa gaaccgtctt tggagcattg
     8521 gccaaaatgg tcagcagcca gcctaaggtg ctcacaactg aaccaagcat aattaccttc
     8581 ttacgaccaa tagcatctga caaatgacct ccatataagg tcccaataaa gcctgtaaag
     8641 ctagtcacca tcattagtat gcctgtccaa aaggcgccaa agtagcttgt atagtacatc
     8701 gccataaaag gaaagatact actgccaagc gtaatggtaa taaagcgcac aaactgcctc
     8761 acttgtattt gcttaggcaa ctggaaaaat tctcgcatga tatcctctct agtatttgcc
     8821 caattctctc aagctggtat gattttcttg aatacgacgg aacatctttt ccatgtccgc
     8881 cttactgaaa ttaatcaaaa caggtctacc atgtgggcag ttataaggat ttttacattg
     8941 agcaagctgt aaaagcagct gtcttgctga gtaatcatct aagctatggt ttgccttgat
     9001 ggaacgttta cagctcatca taatcgctaa ttctgctcgg taggttttga tggatacttc
     9061 atttgtcaac aatagcatgt cacacatttc ataaacgcca gattcaatct ctgcctcctt
     9121 catccaaata ggatgctccc taagaataaa ggtatgattg ccatatggct ctaaatagat
     9181 accaacctcg ttcaaaagtg acattttttc ctgaaggtta ataaaatctg acccagaaaa
     9241 ttcaaaaaga tagggcacca gcaattgctg taggctattg tcaacctcac caatcttgtc
     9301 acgataatat tcatacttga cgcgctcctg agctgcgtgc tgatcaatga taaacaagcc
     9361 atctctgcct tgggcaaaaa ggtaggttcc atgcatttgg ccaaaataat caagctctgg
     9421 aaagactgac tgctcttcat tttctaaacg atcaagcatc tgagataatt tttgcttatt
     9481 gtggacatca agacccgggt gctcactatc agaaagcata ggatctggcc gactagcata
     9541 tttaacactt ggagcagctg cttcagattc agtcttggtc atctgcaaat tgtcaacctg
     9601 cttgacatca ttgtcaacca aagtttcatg gttaaagccc tgcgggctat cctctgaaac
     9661 cactgtttcc ttggtaaaga aatcattttt ttgcagatca taataaagct gactaggctg
     9721 taaaggcagg ctggtctgct caggctttga aaatgaacgt gtgctggacc tagctaaatt
     9781 ttccaaggca tcaggaatca agtcctgttc tcgcaggctc tctgagatag ctgtactaat
     9841 cagggccatt aattcacgct ccttagaaat tctgatttcc tgcttggttg ggtgaacatt
     9901 gacatctgcc agataaggat caatttgaat atcaatgaca gctataggaa agcgtcccac
     9961 catcagctta gagccataac catctaaaat ggctcgattt aacaagaaat ttttgatata
    10021 gcgaccattg atcaggatag tgatgtaatt acgattagct cttgtcaact ctggcagact
    10081 cacaaagcct cccacctcaa aatctaaatc agcactagaa atgtcaatca tttttttagc
    10141 agtattcagg ccatagatac cagcaagcgc ttgacgtaaa tctccagtcc cagaggtttg
    10201 tgttagatgc ttgccatcac tgatcaatgt aaaagcaatc tctgggtgag ccaggctcaa
    10261 gcgattgacg acatcaacaa catgagacag ctccgcttgt aagctcttca tgtatttcag
    10321 tctagctggt gtattataaa ataggttttc taccttgatt tttgtaccaa caggtgttga
    10381 gacagcttcc agctgctcaa tcttaccgcc actagcaact aatattgacc catgctctgc
    10441 atcagctgtt gctgttttga tcgttagttt actgatagag gcaaccgaag gcaaagcttc
    10501 tcctcgaaag ccaagtgttc tgattctgaa caaatcactt tgacttttga ttttacttgt
    10561 ggcatgacga cgcaggctca ggggcaggtc ctcatgagac atgccttcgc cattgtcagt
    10621 gatttgaatc attttcaagc cagactcttc tatttcaaca gtaatctgac tactctttgc
    10681 atctatggcg ttctcaacca attctttaac aacacttgct ggtctttcaa tgacttcacc
    10741 agctgcaatt tgattggcga gaacctcagg taattcgata attgttgtca tatatttcct
    10801 cgcattctta tggactatta taacataaaa ctaaaagagc caagcatcag agctagcaag
    10861 ggtcttatgg tcaataaacc aaaaagcacc tgtggcctgg tgagcctaca agtgccttta
    10921 acatctgata ctagctttta cagtagcttt tttagctcat aaagaacggt catggcctga
    10981 atgggagtta gattcatcac atcaacactc tcaagccttt taataatctc actagaggag
    11041 ccatcatctg taaaaagtga tagctgctga ttagccagct gctgagtctc tcttacttct
    11101 gtagttgata agacgaactc tcttgcttgt gattgagctt ccagcttggt tagcacagca
    11161 tcagctctgg ctagtaaatc ctctggcaat ccagctattc tcgccacatg aatcccatag
    11221 gatttatcag caggaccttc ggcaatctta tgtagaaagg ttacatttcc atctttttct
    11281 aacgtcgcaa catgaacatt aaccagcttt gtcaatttgg ttgacagctc tgtcaattca
    11341 tgataatggg ttgcaaacat agtctttgca ccaaccctat catgaatgta ttcgatgata
    11401 gattgggcta gtgccatacc atcataggtc gctgtaccac gccctaactc atcaaacaaa
    11461 atcagagaat gaggggtcgc tcgcttaatc gcatgattgg cctccatcat ctcaaccatg
    11521 aatgtagact gacctgagat caaatcatct gctgcaccaa tcctagtaaa aatagcgtca
    11581 aataaaggca ggctagcaga ttctgcagct acaaatgaac ctatctgagc cataatgact
    11641 gtcaaagcaa gctgtctcat atacgtagac ttcccactca tgtttggtcc tgtaatgagc
    11701 tgaatacttg tctgtggacc aaaggaaatg ctgtttggaa tatactcctg aacacctaga
    11761 accttttcaa caacagcatg ccgaccattg tcaattgcaa tcctgctctc ctgattaaat
    11821 aatggtcgaa catagtgatt cttctctgca accactgcta aactttgtag gacatcaaca
    11881 gttgctagag cttttgctaa ctgctgcagc ctatcgatgt aggtctccac ttgagcacga
    11941 atacgcatga aaatatcata ttccaggcta gatgactcct ctctagcctc aagcatttgt
    12001 ccttcaatct tagctagctc tgctgtccca tagcgctcag aatttttcag tgttgccttt
    12061 ctaaaaaaat ggtcaggaac catacctaga ttagagttgg tcacatgaaa atagtagcca
    12121 tcttttttgt tatagtcgat tttgagattg cttatcccac tagcctgtct ttcttttgcc
    12181 tcaatatcag caatccagcc ggtaccttct cgcataacct ttcggtaatg atccagccgt
    12241 tcatcaaagc ctgttctgat aatattgcct tcattgatag tagcaggagc atctggatct
    12301 atagctgacc gtatcaggtg ctctagctca ggcaaagtgt caatttggtt gacaagcttg
    12361 tcaaggtaag gactgttaaa ggcctctaaa atagccttga tataaggaac tttagccaaa
    12421 gtatgaccta gctgtaatag atccttgggg tttgcttttc caaaagatac tcgactagat
    12481 aagcgctcaa tgtcgtaaac accctttaaa ctatcgctta gatctgtcct ttcaataaaa
    12541 gcattaagaa acacctggat aatttcctga cgttctagga tcgcctcgct agtcacaagt
    12601 ggcctatcaa tccaagtcct taatagacgc atacccatgg ctgttttggt ttcatcaagc
    12661 aaccaataaa ggctcccatg ctttttacca gtacgagcat tttcaagcag gtcaaggctt
    12721 gatttggttg cataagacat ctgcaaataa tccttaatgt catagtgcac caaggcctgt
    12781 agatggctaa gctcacgcag ctgggtttga tgaacatagt gtagcagctt acctgctgcg
    12841 gacagctcga ctgctgttag ctgatgatca atcaaaggcg aatcctctag tgctgtcatc
    12901 tcaaaggaca gcaaaagatt catctgcttt actaaaatag cctgctcttc ttcagataat
    12961 tcaaagccta aaagaacctc ttttgccttc aggttttgaa tctcactttt gacactggca
    13021 aaatctgcta ggtctgtagc aaaaaattct cctgtagaga cgtccatata agacaggcca
    13081 taagccttgc catcaaaatc aacagccacc aaaaaattat tgggactatc aggtctgctt
    13141 gagtccacag ctgtccccgg ggtaatgacc tgaaccacct cacgcttaac aacaccgact
    13201 gcttgcttag gatcctccat ctgctcagca atagcaacct tatgccccaa atcaattaaa
    13261 acatcgatgt attgttggac agaatgatag ggaacacctg ccattggaat tggattgtca
    13321 gcatttttat tacgactagt taagccgatt tctaaaatct gcgctgcctt aacagcgtct
    13381 tcataaaata actcataaaa atctcccatc ctaaaaagca aaaaagcatc tggataattc
    13441 tttttgatgt ccagatactg ctgcattccg ggagaaacat tagcctttgc catcattgaa
    13501 ctccttattt aattcatctt ctatagtccc tgtaatgtac cgaaccaagt cactagcgtt
    13561 ttgcattttg tcacgataat catctatcaa tggttgatga tctaaatctt ctcgtaattg
    13621 ctgagcctta aaagctgatt cttcagctgc tttatcctta gcgatttgac gaaaaagata
    13681 ggtgtcctgt tgatgtcgct tcatctgata ggccttttga ttataatcag tcctttgaag
    13741 cagctgctga gcctccttat aagctataat gcttgagtgc ttttccagtg ctgctatcag
    13801 ctgatgtaag gattcgcggt aaggcatatt atagaccagc agctaaatct ttttcaaagc
    13861 gcttggcaat ctcctcatca cgacaaataa caagtaaggt atcagcaccc gcaatcgtgc
    13921 ccaaaacgtc ctcaatggca tcattgtcaa taagatttgc caacacgtct gcttctccca
    13981 gattggtatg gagaaccagc ataaagcccg cccggtcaac ctttaggaca taaaagcgca
    14041 catctggact aaatggtgtg gcaacaggct cagaaagact atagtatagc ttacctctgt
    14101 catctcttaa tttaagtaat ccgatttctc ttaaatctcg tgatagggta gcctgagtga
    14161 ccacgatacc atccttttga agaagccgtc taatctcctc ctgtgtaccg atgtgctcag
    14221 cttgaataag ttgcttgatt tgctgctgcc gttctatttt attcatgata tatctcccca
    14281 atgtataatt atcctctcaa attataacaa aaaaatggta gtatttcatc tcagctctgt
    14341 caatttgctt tatttttatt ttaaggaagc attatttctt gctcatatca ttagaccctt
    14401 agatttggca agctttgctg ctctaattct ttagctttgt tccccaaaac acctacaagc
    14461 cttctagtat aatttctcaa tagacacctc gtttatttcc aagaaatgtg ttagaatagg
    14521 gtgacaaact atttttagga gaagcaatat ggacactaaa actctgattg cagctgagat
    14581 tgctaagatt gttcctgaac tagagcaggc tgccattttt aacttacttg aaacacccaa
    14641 aaattctgac atgggagact tagcctttcc agcctttagt ctagcaaagg cgcttcgcaa
    14701 agcaccacaa gctattgcta gtgatttagc tgaaaggatt gacgccagcc aatttgagaa
    14761 ggttgctgct gttggtcctt atgtcaattt ctttttagat aaggctagca tttctgcaca
    14821 ggttcttaca caggtgattg ctgacggagc tgactatgct caacaggatg aaggacaagg
    14881 acgtcatatt gctattgata tgtccagccc taacattgct aagccatttt caatcggtca
    14941 cctgcgctca acagttatcg gggacagtct tgctcatatc tttgcaaaaa tgggctataa
    15001 gcctgttaaa atcaatcacc taggtgactg gggcaaacag tttggtatgc ttattgtagc
    15061 gtataagaag tggggaaatg aggccgctgt tcaagcacac ccaattgatg agctcttaaa
    15121 gctctatgtg agaatcaacg cagaggccga ggcggatcct agtattgatg aggaagcacg
    15181 tgagtggttc cgcaggctag aggagggaga tcaagaggct acagagcttt ggcagtggtt
    15241 ccgcgatgaa agcttgattg agtttaaccg actctatgac cagctaggag ttagctttga
    15301 tagctataat ggtgaagcct tctacaatga taaaatggat gagatccttg agcttcttga
    15361 ggacaaaggc ctactagtcg aatctaaggg agctaaggtg gttaaccttg aaaaatatgg
    15421 tattgagcac ccagctctca ttaaaaaatc agatggagct acgctttata ttactcgtga
    15481 tctagctgct gccctttacc gcaagcgtac ctatgatttt gcaaaatcag tttacgtggt
    15541 tggcaacgag caagctgcac acttcaagca attaaaggct gttcttaaag aaatgggcta
    15601 cgattggtca gatgacatga cacacgttgc ttttggcctt gtgacaaagg gcggtgcaaa
    15661 attatcaaca cgtaagggta atgtcatttt gcttgagcca acggttgcag aagccatcag
    15721 cagagcagca aaccaaatcg aagctaaaaa tcctaagctt gccaacaagg aagcagtagc
    15781 tcatgctgtt ggtgtgggag ctatcaagtt ctatgattta aaaacagacc gtatgaatgg
    15841 ctatgacttc gatcttgaag caatggtatc ctttgaagga gaaaccggtc cttacgtcca
    15901 atatgcacac gcacgtatcc aatctatcct gcgtaaagca agctttacgc cagctaccga
    15961 tacaagctat agccttaatg atcctgaaag ctgggaaatc attaagctta tccaggactt
    16021 cccacgtatc atcaagcgtg cttttgataa ctttgagcca tcaatcatgg caaaatttgc
    16081 tattcacttg gcacaaagct ttaacaaata ttatgcgcat acccgtatcc tcgaagacaa
    16141 tccagagcgt gacaaccgct tagcgctttg ctatgcaacc gcaatcgtcc tcaaagaagc
    16201 gcttcgtcta ttgggtgttg aggcaccaaa tgaaatgtag actaataagc ctaagctagc
    16261 gagaataagc tagtctaggc ttttttgcta gtcttcaaaa tgataggctg ttaaatgatg
    16321 attcttgacc tcataaattt ctgttgctac cttgttaaca aatgctaggt catgagaaac
    16381 caacaaaaga gcagctggat agtcaatcaa gcaagactcc aaagcctcaa tagcgacaag
    16441 atccaaataa attgtcggct catctaaaat caaaagctga tgatctgtca gcaaggcagc
    16501 cactaacgcc aaacgaaccc tttccccacc agataagata gccacctttt gattggcctt
    16561 atcataatca atgctcatca tagctagata atttaaaatg gtgaccctat cttggctgga
    16621 ctgccgacta atgaactcta ctgctgtctg atccagctcc aaatcagcct gatcctgttt
    16681 aaaataggtt atccttagat tttgcgcata aaatccagat aaggcctggg ctgccagctg
    16741 atctaaaaag ctgcttttac cagccttgtt tctcccgata atcgctagct tgctatgtga
    16801 tctgatcaca ataccaggat agtcaaacaa taactgatgg tcccttgtaa gggtaccttc
    16861 ttgtaggtgt aaaagagtat ttggcagtgc gccttcattt ggatcctttt ttaattttgc
    16921 ccaagccttt ttgcgcggcc tgttaacctc tttcattcga gtgagtcgat gttccatagc
    16981 tttagctgct tttgccatag ccttggcctg tgaatcatag ctgcccgcaa aggaattggt
    17041 tttccaatct gaccgagaaa ctgatttttt ctttacagcc attttgttag cctgcgcctt
    17101 ttttcttgtc aggctttttt tcagttgatt agtctttcgt tggtattcca gaaaagctct
    17161 tagctgctta tcctcctcta gctgtctaga acgctgataa tcatcataat tgccatggta
    17221 agtcttgatc gtttgatgct caagcaacca tattttctga ctcaattgat ttatcaaata
    17281 ccgatcatga ctgaccacca gcaaggtccc tcggtagcgc ttcaattgat taatcaacca
    17341 atcacgatta gcatggtcta aataagagct tggctcatct aaaattaaca gagaaggtct
    17401 tgcttgaaaa gcctctttta ggtaggacat tgccctctca cctcctgact gagggctagt
    17461 ggacttgatt tgcggaacat aagcaatatc tccatgcacc tgcaaaaagc cactatagtt
    17521 agtgctttct ccgataattg tctttaaaaa gctggtcttt ccagccccat tatcaccaat
    17581 gatgaaaacc ctctcacctt gattcaatgt aagagaatct attgtcaata agtttttttc
    17641 tgctgtatct aaagcataat gctgaatact aagtgcttcc atatttattc ctttctatca
    17701 tcagaaaggc ctgaaaaagt gcgcacaaaa agccctgatt tccaagcctc aaagcagaca
    17761 ctaatccctt gctgttaatc atagattagt gcttgacaat gagttaattg ttaatcatgg
    17821 cctttttcaa cctcttattt ctgcttattt tcttcatttt aacatgtttg attttttctg
    17881 taaagccttc tcaattggtt tgtcaaaatt tttgcgacga atcttgaagt ctgagctgat
    17941 tacctcatca acatcaataa tagagataaa ggcgtctgga tctagctctg ctaaaatacg
    18001 cttcacctct cgcacctctg ttggattgag cgtcacgtac ataatattat aatcatgacc
    18061 agaataagcg ccttgtccct ttaaataagt cactcctcga ttgatttctg tcaagatcgc
    18121 ctgcgccgcg gcttgcgact gcttagtgat aataatcata ccacgaatgg tatagccacc
    18181 attttgaaca acactaatca tctggctaaa gacaaagcta gccactaatg tatagagcat
    18241 atgcttcaaa tcaacataag tgagagaggc tgttaatacc aaggcatcta caaataacag
    18301 ggtttgcccc agcttagcac caaacttttc ctctgcaatg cgggcaataa tatcagtccc
    18361 accagttgtc gctccatatc gaaaaacaag gccactacca attcctgcaa acaagcctgc
    18421 aacaaccgca acaagcatca tatcattctc taaaccaagc tccataggca ccttttgcca
    18481 cagccagata aagactgaca taagaacggt tccataaatc gttaaggcta gggagcgcct
    18541 tccaaaaatc ttagccccta acataaataa aggcagatta aataaaagtg acgaataagc
    18601 cggattgatc ccaaaatgag catgcaaaat caaggtaatt ccagctacgc caccctcagc
    18661 caattcatta gccatgttga aattaacaaa accaaaggta tagatagcaa cacccaccgc
    18721 aatcaataat agctctctta cacgatgcca tttgtcaaga tttgtcattc actttcctca
    18781 ctattcatta catttgttag gtaccagatg aaagctcaag gacggccatt taatagctac
    18841 actacaataa gcttgacagc ccagcgcttt cattagcata atcaaaggct atgaatgtga
    18901 tatcccagcc tttatctttt tttcgtttta tggtatttac tttttgtggc gataaattcc
    18961 ggactattga cttcgttaac atcaaagaaa gaaacaaaag cattgggatc aacctgtgct
    19021 ataaaggcct ttagctctcg tacatctgat cgacctagag ctacataaat aacctgtttc
    19081 tcacgaccag agtaagcacc ctcaccatgt aaataggtga ctcctctacc gagctcctcc
    19141 ataatgaatt gtgaaatagt ctgagaataa tctgaaataa taaaggttcc gcgtgcagaa
    19201 taaccaccat tttgcaccag atgaacaatc ctactataca taaagctagc aatcaaagca
    19261 tacatcatct gcggtattga aatataggtc aaagaaacca ccatgacaaa aatatcaatc
    19321 cctaataagg cttgattgag ctgcaagcca aacctatcct ctatcagctt agcaataata
    19381 tctgagccac caatcgtccc accatttcta aaaacaatgc cgccacctaa acctccaaga
    19441 attcctgcca gcaaggacac tactaaattg tcatgatcta agtcaataaa aagggggagc
    19501 tgttgaaaca gccaaacaaa ccaataaagt gataaaatac cggtcacagt atacaccatt
    19561 gcccgtctgc caaagagcct tgcacccaac aggacgagag gcaaattaat cagataaccc
    19621 gttattgaag gattgatctg aaacaaggca ttagcaacct gcgtcagtcc cgctagccca
    19681 ttagcagcaa tacgatttgc catgtaaaag tagacaaagg caaaggcata aatagctgag
    19741 ccaagaataa taaaacaaca atttttaagc tttaagctct tattagctgg catatcgata
    19801 cctatttctt agtcttcatc tgattcgaca aagcgaccaa tgattctaac attttcagca
    19861 acagaaacaa aagcatttgg atctgtttta agcatcagcc acttaaattc actatattcc
    19921 tcacgtgtga gaatcgtaat taaaacagcc ttatgctcat gcttgtaggt gccttcagca
    19981 tcattgatac tggttacccc tcggtgcagc tttttatgaa tcatgtggat caccttgtca
    20041 ggacagctgg tcacaatggt cgcctgcatt ttcttttgct tggtaaaaat cgcatcagtc
    20101 actcgactag aaacgaaaat agtcaccatc gaataaagcg catactgcca gccaaacaac
    20161 agtcctgcaa aagccataat cacaccattg atcatcaatg aaaggttacc gacatctttt
    20221 cctgttttct ttctaagtgt cagactgata atgtccgtac caccactaga aatgcgagac
    20281 ttgaagcctg taccgatccc caaacccata accaagccac caaatatagc attaatcagt
    20341 gggtcagtcg tcaaggtcac ctgaggcatg atttggataa agaaagagct catactaacg
    20401 gtaataaagg taaaaatcgt aaatttatga ccaatcttat accaagctaa gactaaaaga
    20461 ggaatgttaa tcacgtaaaa agctaaagca acaggaatct caaagcccca taaatggtgg
    20521 ctgatggcag agataacctg agcaagtcct gttgcaccac ttgagtagac atggcccggt
    20581 tggaaaaaga aattaacagc tatactagac aatatgccat agagtaaaga ggccgaaatt
    20641 ttctctgtat acttctcctt ggaaatgctt tttacggcat gaagcaagcc aatttttttg
    20701 gctcctctat taatcaggta ttttactctt ttcctatagg ttgttttttt aatcatgatg
    20761 ttctatttga agctgaagct cctctaattg cttttcagat accagactag gcgcctgtgt
    20821 cattggatca gatgctttat tgtttttagg aaaggcaata acctctcgaa tgttgtcctt
    20881 gccagcaagc agcatgacaa gccgatcaag accaatagca agaccaccat gtggtgggaa
    20941 gccatactcc atagcctcta gtaagaagcc aaattgctca ttggcctcct cagctgtgaa
    21001 gcctagtgct ctaaacatac gctcttgcat gtctttttgg ttgatacgaa ggcttccgcc
    21061 accaagctca tagccattta agacaatatc gtaagcaaca gcgcgaactt tggctaaatc
    21121 accctctagc tcatgggctg actctgctgt tggtaatgta aatgggtgat gagcagacat
    21181 gtaacgctcc tcttcctcag accattcaaa catgggccag tcaaccaccc ataggaaatt
    21241 aaactgagac atgtcaatca tgtcaagctc ttttgcaata cgtgtacgaa gagcacctaa
    21301 ggtattattg gctacctcta aggtgtctgc aacaaacaag accaaatcat tatgctcaag
    21361 ctgtaaagac tctgtcaact tactttccac acctgtcaag aatttagcaa ttggtccagt
    21421 aaatgcacca tcaaccacct tcagccatgc cagaccctta gcaccaaatt gcttagcaaa
    21481 ttctgtcagc ttatcaatat cctttcgcga gtagcgatcc gcatgtccct tgacaacaat
    21541 tgccttaaca gcctgtgcct cagaaaacac cttaaagtca atttccttga caagatctgt
    21601 caagtcttgt aaaagcatat caaagcgtgt atctggctta tctgagccat aatgattcat
    21661 ggcgtcatca taagccatgc gcggaaatgg cagcttaacc tctattccct ttgtatcctt
    21721 cataaccttt gcaatcatac cctcaacaat atcttggatt tcttgctcag ataaaaatga
    21781 cgtttccaag tcaacctgtg taaactcagg ctgacgatca cctcgtaaat cttcgtcgcg
    21841 gaagcactta acaatctggt aataccgatc aaagcccgca ttcattaaca attgctttgt
    21901 gatttgtggg ctttgcggta aagcatagaa atgtccctgg ctgatacggc ttggtacaag
    21961 gtaatcacgc gctccctctg gtgttgactt tgtcaacatc ggtgtctcaa catcaataaa
    22021 tccaagatta tccaagtaat tacggataac atgcgtcgtc ttggcacgaa gcttaaagct
    22081 ttccagcatt tctggacgac gaagatctaa ataacggtag cgtaaacgcg tatcgtcact
    22141 aacctcaaca ccgtccttga tttcaaacgg tgtcgtttta gctgtattaa gaatggttaa
    22201 gcctgaaacc tttagctcca ctgcacctgt agctagctta tcattaacct gctgacgcgc
    22261 ctcaacactt ccttccacct caatcacgta ttcactgcgt aagcgctcag cagtcgccat
    22321 cacatcacct gaaacgtcct ctggattaat aaccagctgc atcactcctt cacgatcacg
    22381 caaatcaatg aaaataaggc cgcccaaatc acgacggcga cttacccaac cttttaaaac
    22441 aatcgttctt ccaatatgtt cctttcggac gtgtcctgca tacatgctac gcttcataaa
    22501 taagatacca agagcaaata aagagtcagc actccctacc tgtctttgtt cctttctcta
    22561 attaaaaata tcattaccac ttattataac aaaaagcaat taaaaacccc acccatttga
    22621 gtagagtttt taagaaatag cagagcctat accttagctt tgcctgttta gccaattgac
    22681 tgaaagtaag gcagtggcaa ccagccataa caataacacc acaagcttga taactgaaat
    22741 ggaatgtccc aaataaaccg tctctcgaat caagtctcct gctggtataa atggcagaaa
    22801 atgatatccc cttaaaataa cctcaggtat acgttctgca ggatacatta taggtgaaaa
    22861 caataggcca atcatcaaca ataattgggt tatcaacgtc attgtacttg gagttgacca
    22921 ataagcaatg gcaaatccca tactgatcat tgtcattaaa actaatggca aaatgagaaa
    22981 cgtcgctaag gacagctggg gcaatatttg aaattttaaa taaacaaccg caattgacac
    23041 accaacacca atcaaagcag ttaatgtcca aatcaataga tcagatagca ggatcaagct
    23101 tcttaggacg ggtaatgttt gaatatagct cacaatgcca tctcttttat cactactgat
    23161 tgattgtgct gataccgtac agccaatggt aatcatacca atcgttactg agccagaagc
    23221 aagatagtag actgtttgca cagtatcatc agcaataata agtgaataac cgtaaaccag
    23281 tgcaattgtc ataaaaaatt gaataacgct acacaataat atcaacgatt tatggcgaat
    23341 aaagctccaa tttaacaagc ttagaaattg gtaagtaaca ctaatcttct tcatctgaca
    23401 gctcctcata ataatcattt aaccctaacg tcgtgatact atattgaaca atggtatctg
    23461 atgacaaatg tatgcctaac caattcaata atgctgtcat ttccttatta tccattattg
    23521 ttatagcttc attgtcatcc ccaccaagtg agtaagcaaa cgggtattct tccaaggctt
    23581 tttgatctct aaataaaatg gatattctac tctttggatt actagataga tttcttactg
    23641 ctcctgagct ttttacttcc cccttttcaa gcaaataata agcatctgca tatttttcaa
    23701 cctctaaaat attatgggtg acaacaataa cgatatgtcc ctttgccgcc atctttttta
    23761 agtataacca taattttata cgtcttatag gatcaacatc atttgtcggc tcatctagta
    23821 aaacaatctt cggagcagca ataacagcca ttgcaaacga cgtcaatctt tttagtccac
    23881 cagagagttt ctctccgaca gtattttgcc acttaataag accgagttct tgaattaatt
    23941 cctgaacctc tgtctccaat aattttccgg acagccctct gatccttcca attgatgaaa
    24001 tagcttgttt aattgtgatt ccttttaagg gagcatgtag ctgaggcatc attgacgtat
    24061 tttttctagc aattttaggt gatttgacaa acgaacagtc tagaaatgaa atatcaccca
    24121 catcaggttt tatattacca ataatctggt ttagtagggt tgttttacca gctccattat
    24181 gacctatcaa ggctgttatt tcactggatt taaagacaca atgtaaatcc ctattggcat
    24241 aagagccatc tctggcatac ctttttgaaa gtgacctcac cattaattca tattgttcca
    24301 ttgattaact cctacccata atgactaaat atttcccaat cattactgtt gccatgacca
    24361 caagtcggac actctttgaa acgtggccaa ggcttatgtg taaatgaagc acctgtttca
    24421 taatttattt caaactgagt agatttactc ataggtatac aaaaatttgt caatattctt
    24481 attgcctcat ctactattgc tccacttaac tgaaaaattg ctggtccata ggctactgtg
    24541 gggggattaa agttgatttt ttgaaatcca acaaattgat caataaaatt tggtgaagtc
    24601 ttagtatagt ggatatttaa acaatcaaag cagcctgttt ctccaggaac aacactatat
    24661 actctgcctc tacttacttg agagccacca aaaacacaag ggacaccagc ttttatgata
    24721 gcttcattaa ccctcctttg agctacaaaa ggaggctcat caatagcaca aatgactaaa
    24781 tcaatatcta ctaataaatc taaaacatca gtagttgaat tgattttttt atctattgta
    24841 gttaatttaa cagatgaatt cattttttca aactctcttt ttgctactac agtttttaat
    24901 tcaccaatat cactttcttt atatagcatt tggcgcccta agttatttct ttccactcta
    24961 tcgtaatcca caatagttaa ctttttaggt cctaaccctg ctaatagtgt caaaatattt
    25021 gaaccaccac cccctaaacc aagtagtaat attgaactat tgttaatttt cttctgaaca
    25081 gccaaactat cttcataact atcaagatat cttctgaaat aattcacatt tgacatatat
    25141 ctgtcatcta ctgagtcatt ttgcccaaac tcctctatta atccttcatt agcaagcaaa
    25201 tcaatcccat attcaattgc tgataacgtg atattgggaa ataactcctt catttcctta
    25261 aagataatat ttaactctgt tccatttaaa cgtgttacta attcccacaa ctcccccgtt
    25321 ggatcattaa attccgtcgt aatattaatt tgagcgccta ttcgaaacat ggtatcactc
    25381 agtttataaa ttggataaat atctttaata caaggtctgc tataattcat tttttaccct
    25441 cctaaaaata ttaaagtagg ctgataaaaa cagcccactt tagagtattt aaatgactac
    25501 ccatgaaact tccattgttt ccatcggttt acgcactgtt acttcagtca ttttcataga
    25561 ttcattttat caaaacattc agtctattat tattattttg taaaaaatag cgcttttcat
    25621 gtcatttttg gtatactaaa taccacagtc tataggatta tgggggggac catgcttaaa
    25681 attgctcttt gtgatgacaa taaagctttt gcaacagctg tagaagatct attataccaa
    25741 tataatcaat tagttccagt cgagttagat atttacgaag atccttatca attaatacag
    25801 tcactgtcta atgattatca tatttttctt cttgacattg aaatggataa catgtctgga
    25861 atagcattag ccgagcatat taggaaagat aacctctctg ctattattat ctttttaaca
    25921 agccacaaag aatacatgga aaacattttt catgtgcaaa cctttgatta tctgattaag
    25981 cctttaaatg aaccttattt ttttgagtgc ctaaatagag ctctaagggt tttagagctt
    26041 gataaaaaat tttttacctt ttcatctcac cactcctact atagcttaag cttaaacgat
    26101 attatttatt ttgaaaagga aggacgaaaa gtactcattc ataccaagga caagacctac
    26161 tctacctttt tatcaaccaa agcattacta aaagagcttc ctgaacaatt tatccaaacc
    26221 catcattctt atgtgtttaa cgtcaattac ttctataaat ttgaaaacaa tgacataaca
    26281 ttagctattg ataacacgcg cttttttatc attcctatca gtcggaaatt taagaagggt
    26341 attcaggaga acatcttttc caagctaagg agagtaaatg gttattaacg ctatttttca
    26401 tctttataca tcagttgtta atattgtgat tgttaattat ttttttcgtc agaaaaatgg
    26461 tcagctagct acccctaaaa atataggtta tctctctttt ttagtattca tagaatgctg
    26521 cactcatttt tttgtatcag aaagctatgc ctcactgata accctgactt gttctttgct
    26581 aacgtcactg ataatatcta gtagctatca ttactccatg aaacagtgta tcttttggtc
    26641 tgttacactt caaagcatag ggatcttgct agaagcaagt ttagggatcg ttttaatatc
    26701 tcttaattat caaatctctt ctatcagtgg gacattttta ttcataaacc tgctcaccat
    26761 atccagtagt atccttatat ttgtattaaa gcagctcttt ttaaagacta cagacaattg
    26821 gcttgatgag caaacacaaa ccaactggat actaaagcta tctattattc caatgataag
    26881 tctttctctg ctactgctac agcttcttcg attaaaagaa gaacctttat ttgacttgtt
    26941 tacaatacta ctaacacttg gatttatcat tatcacgatt acttcgcttt atctgtatac
    27001 ttacatttca gagcagcatt tacaaatgca agacattaac ttagataggg tacgattcca
    27061 gtcagaactg aagcatttag aaaatgtaaa ggaaaatcaa ttaagcatta gggctcttaa
    27121 gcatgatcta cataatcaaa acattgtcct attaggactt ctggagcaaa agcagtacac
    27181 taaagcccaa caattactga atcataacct taacctgcta gatgggacag atactttctt
    27241 taccaatgat actattttaa attatttact taatcaaaaa gcagtcgtag ccaaaaagaa
    27301 tggcattgtg ttagatattc actgccttat ccctacaaac ataagcctaa agactgaagt
    27361 tatttcagtc attataggaa atctacttga taatagcatt gccgcaacta ttcgcaatca
    27421 aaataaagct gaaaaacaaa tacaattaaa ggtgagactc tttaaaaatc aactccacat
    27481 tgatatcgaa aacttttttg atccaaaaga gcttgcctcc agaagtcaac gaaaaaaaga
    27541 cggattggga attaaaaatg ttcaaaaaat tgttcaacag tattatggac tataccagca
    27601 aaccatagac aataacatct ataaagtcag tattatcttc tctaacattg ttttagtttc
    27661 tcaacaatag cattaaccca tcaccagcta taagtatagc tgctgacatt ccaaataagg
    27721 gtgctttcaa actgactact aaagatggga aaaataatcc ttagtatagg tataatatca
    27781 caaaatcaca caatatcatt gctactaaag caacgacatt gtgtgatttt ttagtatctt
    27841 aatgactcat accacttttt tcagtttttt tgctttactg gatacattct gcaaaaatgc
    27901 tggcaaaatt tgtttggatt tgatcaaagc taactgtcat ctcttgacga gtttgattat
    27961 gcttaaggac agcttgacct gctttgattt cactttcacc tagggtgatg actacctttg
    28021 ccttgaaagc atcagctgac ttgaattgtg ctttgatttt acgtccgagg taatcgcgtt
    28081 ctacggtgaa gccctgacag cgaatggcct gtgtcaaggc tagcgccgcc acattggcgt
    28141 cagcccctaa aacagctatg taaacgtcca agccttcttc gactggcagt tcaacgcctt
    28201 gcttatcaag gataagcaaa agacgctcca gaccaagtcc aaaaccaaag ccaggggttg
    28261 ctggtccacc aaagtactct acaagaccat catagcgacc gccagcacaa atcgtcagct
    28321 cagactgatc cacctctgta atgaattcaa aaatcgtgtg gttgtaataa tcaagcccac
    28381 gcaccatatt ggtatcaata acataaggaa tagcaagtgc ttcaagcatg ctgcgcacag
    28441 catcaaagtg agcctgactc tcctcgtcaa gataatcaag aatagatggg gcatttgcta
    28501 ctgcaatctt atcctctttt tccttggaat caagcacgcg cagagggttt tcatctaaac
    28561 ggcgctgact atccttggac aaggtctcac gcattggaga taggtaatca atcaaggcct
    28621 gacgataggc tgcgcgacta gctgcatttc caaggctatt caaatgcaag gtcacctctt
    28681 taataccaag cctttcaaag aggtgataag ccatggcgat cgtctcaaca tcagtggcag
    28741 gattggcaga gccaaagcac tctacaccaa tctggtgaaa ttcacgcaaa cggccggcct
    28801 gcggacgctc ataacgaaac attgacccaa tataatacag cttgacaggc ttttgaacct
    28861 ctggcgcaaa gagcttgttt tccacatacg aacgaacaac tggggctgtt ccttctggac
    28921 gaagtgtgat atgacggtcg cccttatcat agaagtcata catttccttg gtcacaatat
    28981 cagtggtatc acctactgat cggctaatga cctcataatg ctcaaacata ggtgttcgga
    29041 tttcaccata atggtattgc ttaaaggttt cacgtgcaac accttcaaca tattgccact
    29101 tagcagcagc cacaggcaaa atgtcctgtg ttccttttgg tttttgaagc ttcatattat
    29161 ttcctctttt actagtattt atatatttta ccatagaata gcttcattag tctgttaaag
    29221 tacagaaaag ctacggacca atttaccgcc tcgaatatct aaaacaatca tatcttggat
    29281 atctccactt cgactagatc tactcaccct gtcaaacccc actttatagt agccatccca
    29341 caagcaggta aagtctagac tttttattct atcagaaaaa tccaacctgg ggccagacaa
    29401 atcgtcttgt tcctcttctg acattcgcca atcaaaatct atacgaattt ccaacacgtg
    29461 atttttcaaa tactttgaaa catcaatatg ataatagcca cctattgata gcccagcttc
    29521 tctattatta gatgcatctt gagataattc attcctgcct cgtacaacat cttccctaat
    29581 cagctctcca tctgaatcag aaatcgtctg gacactttgt cctgttacgg atataagctt
    29641 caaatcctca gtctccaact cgctaaatag ttgtttgatc tgagcagctt gcgctttgac
    29701 agctggttgc tgccacatag cttcttccct aattcccatg tcaacttctg catcagccaa
    29761 atcttcctca ggtgatttat aggtagcaat cgaaatacta tccttcagac taataacctt
    29821 accgtctact tcttcgctgt aggtaaaata aagtctctca ctacctgtct caatcatctt
    29881 agtatagtcg tctacagtga ttttcccttg gtatcctaag gtttgaaatt ttttaataat
    29941 agtggggcta tactctgtta caacacgttc tttttctgcc tgtgaaacac cacaaccagt
    30001 caaagcaacg acaaagccta acagacttaa taattttcca aacatcttaa tctcctaaaa
    30061 taaccacctt tgtctcattt taccattttt taggattttt ggagaatagc agagcttttt
    30121 aataaaattt ttgtcaagta actttacttt acatagaaga tatgatatga tactaaagtt
    30181 ggcgaaagcc ataacatcaa atagataaca atgggtcaaa gatttgagac agataggtta
    30241 gcataagatc atgcacacca gtttgtcacc aatcttttaa tagacccttg atcatttaac
    30301 ggaggataga aaaaatggca gttcctgcac gtcacacgtc aaaagctaaa aagaacaaac
    30361 gtcgtacaca ctacaaattg actgcaccat cagtaaaatt tgacgaaaca actggagatt
    30421 actcacgttc acatcgtgtc tcacttaagg gatactacaa aggacgtaaa atcgctaaag
    30481 ctaacgcagc tgaataatag aagggagata ccatgcgcgt aaatatcaca cttgaacaca
    30541 aagaatctgg tgaacgcttg taccttactt caaaaaacaa acgtaacact ccagaccgcc
    30601 ttcaattgaa aaaatactca ccaaaactac gtaaacatgt tgtgtttaca gaggtgaaat
    30661 aagacgatat acagaaagcc cttgaaatca acgtttcaaa ggcttttttg ttttagtttt
    30721 gatgagacaa ctgagtattc tcagctaata caataaacaa aggtacttat gatgataatc
    30781 tttcatatct gccttgggct aaaataacct catcagtgat ctcacaattt aactgtggac
    30841 gaaaaacagt ctgccaaggt cccttttcag agtgcgtcag cttaaccaat tctcctcctg
    30901 ttaaatctcc atactgttta acaacatcta ataatacagg cacaatcttc tttgcgtctt
    30961 cgaccaatag cattctacct aaggcttgcg gaagatgtat gtcttttaaa atatattctg
    31021 tatgatcatc gatatctatc acctcagaac catatttttt aaagctgtga tacacctctt
    31081 ctactacagg accatattga aaagcaacta ttttttcatc aaataaggat tcaccatagg
    31141 caagaagata tgttttataa gcaagataaa ctaacttttg caattgtaag tgtgagagtg
    31201 gacgcatggc taagaaaaat ttagcaacat caatggcact aattttagag tcggattgta
    31261 aaacctgttc aaattcatcg aagtcttgac aaaccataat atcctcaaaa aaggaatcta
    31321 actcaatgac actttgccaa tcagcactat ctgtaacaaa agaatgcaca ccaacatcat
    31381 ctctattgat atgacttagc cgctgcattt tttcttcaat ggcaacatga tccaattgac
    31441 cttctgtcgc taagtgaaag ccaactctct cacctcttgc atatgaacta gcaactaaaa
    31501 taaaatgctg atacatatgg ttattcctcc ttttctaaat tagcatcaaa ataatgttgg
    31561 ggtagtgata tatattgtcg tttttgctta tgctctttat gtgacagctc atttaagcgt
    31621 gattgctctg gatcccaaat ctgtaattcc catggaaaaa accgattatt tccattttta
    31681 aaatatagat ggataccttt atagtcgcca tctgttctta aatacaattt agcaatatta
    31741 gtcactcgat gatcattttg caaagcatca aaaacagctt ctaagttatt gaccaagatc
    31801 ctaaatccaa gaaaatcatt caagcattta tttaagggaa tccttccaaa ctcatgattc
    31861 tcgctcatgt agtataaaag cttctcacta atagattctg cttgctttat tctccatcta
    31921 atgcctataa actgatgtcg tatgcttgac acttgactaa tatttctatt tagccttgct
    31981 ttataagaaa cgatgagctc ttggaactcc ctatcaatac gattgttaac gaccaccgaa
    32041 ctgacactct ttttcaaatt aaagcataga agagctccta agcccgaaga aaatgaatag
    32101 tgtaatcgat tgatttcact aataatctca acaacacttt catattgata agctgcaata
    32161 ggcaatcaga aacctccaaa aatagcaaaa aacacaagta tcacatctgt cacctgtgca
    32221 tacctctatc ctactagcta tagtctatct ttttaaagaa tacttgtcaa catttctaca
    32281 cccgaaagca ttttaaagca acaatgtcag ctaagcccag cgtagccttg ccaatcttat
    32341 ggttcaccaa acaccgagat aaagctgtca ccttcatcaa gaatttcctg atcagccttg
    32401 aacatgatca atcacatcat gataaaatca gacgtttaat gattgaatta aaaaaaaaaa
    32461 aaaacgaaac tacggaggcg aattgtccaa aacgtattca cagcctgcaa gcgtcatgct
    32521 aagatttttt ggaggaattt tagaaaaata aacattcgac gatatgtgag gactaaaaca
    32581 tgaaaagaca atcaaacatc agacgcttgt gtcatcaagc cctagcagct actctcatca
    32641 caggaagcct gatgggaaca ggactgcttg gaaataaagt tgtgtatgga gatgttagtt
    32701 cagatgcaga cagtattaaa aaggttttaa cttccggtga gaatctcaag gaatcgttac
    32761 aaaaagttac tgatcctaaa acattatttg gattatttgc tattttatct ggagattttg
    32821 gattagataa cgaaagtgac aaccttgtaa tcacgacact ttctgattta gttagtgatt
    32881 ttagtaaaag cgggaacaac agtaacaata gaaaagcagt tatcgaagaa atcaaaagaa
    32941 gagttctttc tttagaatct gcaaaaaaga atgaacaaat tgctaaaaaa gaagcggaga
    33001 aaaataaaaa agatttagag acagaaaaac tacagaacgg aatactgagt cgtgatctaa
    33061 acgcaagtag agaagcacat agagtacttt caaaattatt tgacgatctt gaagaaaaat
    33121 ttgccaaagc taagatagat aaaaaacaag cggaagagca agctaaaaaa gcaataacag
    33181 ctaaagaaaa ggctgaaaag gacgtcaaaa ctgctcaaca agaaagtgaa caagccaaaa
    33241 aagctgctga ccaagctgaa actgacaaaa agaaggctca agacgaagct aaaaatgcta
    33301 aattagatag tcaacgagct caggaagaag ctaataaatt aaggggagag gctgaaaaag
    33361 ccaagcaaga agctgaaaaa tctaaaaaag atttagaaac tcaaaaagaa aagcttgaac
    33421 aagagattaa agaagctcaa gaatcaaaaa aagaagctga acaaaaacta aaaaagcttc
    33481 aagagtcttc gatgaaaaat gatactgccg ctcaacagct gttaaaagaa aaagaagaat
    33541 taacaacaaa acttcaagac cttcaaaaac aagctgagga aaaaacaact gaaattgaaa
    33601 agcttaaaca agagcttgaa aacaccaaga ataacagtgg tcagctaggt caacaggaac
    33661 aaaagcttca agagcaattg aacaaggttc aagaagagct gaaacaaaag gaaatggaac
    33721 ttgaaaaagc taaagaacag ctgaaacaag aacaaaaacc tcatgaaggt gatgacactt
    33781 ccaaggcaaa aatcgctgaa ctggaacaac aggttcaaac actaaccaag gaaaaagaga
    33841 acctatcatc aacccttgag tcaacaaagg ctcaattgac agagactcag gcaaaactat
    33901 cagaagctca aaaacaattg actgctactc aagaaaagtt aacaacactt gaagccgaga
    33961 aagtagcgct tcaacatcaa gttgagacca tttcaaaaca gctatcagaa gcgcgtgacc
    34021 tcagcgaaaa ggaaaaagca gcactccaag agcagattaa taagctaaag gctgagattg
    34081 agcaaaagac caaggaaatt gaagccttga agcaaggcat gcattcacat caaggtcaag
    34141 aaaaaccaaa ggatccaaag actcctgaga aaaaagatca accacaaacg cctgtccctt
    34201 ggactgctct gacaccagct aagccaattg acactaccaa agctcctaag agctcagcac
    34261 caagcccaca gactggggca gcaacaccta aaaaacaatt accagcaact ggtgatacag
    34321 cgacacctag cttctttacc gccgctgcta tggcagtatt ggctagcgtc ggtgtcctaa
    34381 gtctctcacc tagacgcaaa aaggagcaaa acaaccgtta ataggaaatc atgaaagcct
    34441 tctatgacag tcattgttca taggaggttt tttacaccaa atagaccttc tattggcttt
    34501 tcatttgatt cttaatggat ttttactgct aatttctgac tcaccatcgt tgcattcgtc
    34561 tcattattta caaatttatt tggctaatat tgaaaatatg ttatgattaa tgtattattt
    34621 ttaaaaaata ttattttaga atggtaaaaa atggaggtga gaggagcaat gggtaaccgt
    34681 caaatgaagc tgaaaaaata cttcctcagg tttttattgt tattatttgc tgcaatctac
    34741 atttattttt cctcttttgc ctatcagcat tcctaccttg ggataagtgc tgattatgtt
    34801 aatcatagct gggttgtcag caatatccat aatggtgggg aggctagctc ctcaggacta
    34861 gttgttgggg ataagatttt agagatagac cataaaagca gccgggacaa tcctttgcta
    34921 aataagctat taattgttga gcaagcaacc tcaatgactg ttttgcacca aggcatacaa
    34981 agacagattg tatttcaaaa aacacatgga tctaaaaaga tatttttaat gtttagcctg
    35041 ttatccatta tcttatttgc cttatcctat ggttattcta gaaggcatga gatcagtcgg
    35101 accagtcaga ggtattacat ctttaccttt ttaacatcgt tattactggt ttcgattatt
    35161 ccatcaagca tgggaaatgt tgttgcccgc ttgattttag tgatttacat cactttgttt
    35221 ccctttttta ttgatatgtt ttggagagca ggtacattgc aacaggaatc tgttaaattt
    35281 tcaaaatttt caaaactgat catcacctat tctgctgcaa ctctctgttt attgctatat
    35341 tctaagtggt tttcggtccc actcgtcatt accatttatt tggttcgagg aattttctat
    35401 gttagcttta cctttttagt ggctttattt ttaatcacct tggttaaaga tatcaaaaac
    35461 aatgcttttc caagactcaa tattgtcctg ttggttatcc tgtgcttgct gccattgttt
    35521 atcggctatg tgtttccttt gccctacgat atccctttta tgtacacgat acccctatta
    35581 ctgctgccga ttttggcgat cattaataac ctaatcatta acaggctcac gacctttcgc
    35641 tttcatttgc cagttccaat cctctatatg ttcattgcta tgctaggcac tgtgatgatc
    35701 atttgcttgt atctcatatc agactttatg cctaagtggt taatgattag ttatagcttt
    35761 ttactaaccc tgtgctcaat accaatcgta aaagacctga tttttttaaa tatcagaaca
    35821 ggctaccagc tgagcaacaa gtctattttc ctagcagttg aggctgaaag agaggatatt
    35881 tcgatctacc tgcatgatac gatcatacaa gacattattt attacaaaaa aaggctggaa
    35941 aatatggacg ccgtctcaaa aaaggctgct tcagatattc ttgatgatgt aatctttgaa
    36001 ttaagagagc tgtgctcaaa catttatccc ctgatgattc aagagctagg cttaaagaac
    36061 gctattttag acatcatcgc taaatttcag aaaaaagaat ctgttattat caacgacaat
    36121 atccaagtgg agcagcttga ttttgggcag cccattaata attttatcct cagatcaata
    36181 cgggagctga ttaataatag cattcttcat ggtaatgcta aggaaataga tatacacatc
    36241 tacaatgctg agcaatacgt tgtgatcaag attgttgatg gcggacattt taagactgct
    36301 cgtcagacag aagcgcctca ctttggctta actgttatcg ctgaaaagtt agcattgctg
    36361 ggtggtcaat tgcttgttga caaacaccct acgactattg tcatgctcat tcctagaaag
    36421 caggtgaatt atgataaaaa tagcaattat tgatgatcat gaattggtct tgcaaggcct
    36481 gtatgatcgg ttaaaaaagg aaacacattt tgaggttgtc ggcgctttta ccagctacca
    36541 agatctgtta ttttgcttga aatataagtc tgttgacgtt ttgattattg atctcatgct
    36601 aaaggatatt catggctttg acttaattgc acaaatccag cagaagtgtc agaccgtgcc
    36661 aaaaatgatt ttaatttcag gattttatga gcccttgctg cacaaaagag ccttggatct
    36721 aggcataaag gcctttcttc caaaggaatg ctcctacgac gaattaatta gcactgtcta
    36781 caatgttgca aaggggaatc aagtgattcc agatgacttg ctgcaaaagc aagaaagcca
    36841 tctgctaacc gagtcagaaa ttgagatatt gaaattaatc tcagatgaat actcgaatga
    36901 aaaaatctcc aaaaagctct atatcagcag aaggactgtt gatacccatg tttcaaatat
    36961 atgtgctaag ctcaatgtaa caagccgagt tggagcggtg cgggaggcta tcaggctgaa
    37021 gctgatctaa caagtcaacc aaaaaaggca gacagatatt cgtaaattac ggatgtctgt
    37081 tttttgatag tgttttatca ttagccttgg ttataaataa gaaaaggaga gaaactaatg
    37141 gttgatgtcg atacattact tggtgaccac aaaacaaggt attttggtga tggtcacaaa
    37201 agaacaagct acagtataaa tcatgaccaa aataaccaag cttacggaac aattacccaa
    37261 tcgggtgtgt ggtcaaataa atctgataag gtgattcagc cacacctaag caccttagat
    37321 ggcattgttc tagccagtct agcagctgaa ggatatctaa aagagcaata tgaagtatgt
    37381 gaaggttttt atttatctca gttttcggtc aaatcaggca ggaagcctat tgaagattta
    37441 aacagggttc caattgttgt ccaaaaaagc tctttcaatg gggataaggc aagctttacg
    37501 gtgtcagtgc tggatatgac tgttaatcta gtatttaaac gcattgacac ctatacagca
    37561 aaagacaaca aaccagctgc agaggcaaag gattacttgt caaatcatct aaaggacatt
    37621 caccatcata tctacgatgt taacttttta gacgcattag atatagcaga taagtgctct
    37681 attttttgta aggctaataa ggcaatccgc cacgtcagca attataaggg catatcctct
    37741 cagctatcaa gcagctattc cttattagag ctcttgatta ttttctcaca gatggctgaa
    37801 atgttggcat attatgctga tgatattgat agaagataca gtgaaacctt gtggatgaaa
    37861 aatgtatcag ccgagctcgt tgaaccgata cctgatggtg agctggccct tttaggtaaa
    37921 attaccaaaa acaaattact tgatatgaag ggcaaggact ggaagctgtt tgaaatgtca
    37981 ggtactgaca cacaaaatcg agtgagaatt tcaagtaaaa tagcccatca attacctagt
    38041 tcggagatgc ttaacaatgc ttaataaaga aatcagactt gtcatatcag gtacctattc
    38101 tactggtaag acaacaacag caacggctct gtctattgcg acgggcatac ctttgattaa
    38161 tgcactttca gccagagaga tcctgaccga cctgtatcca ggcagacgct ttcaggacat
    38221 gaatgccact gagctaatgg ctctaggatt aaaaagattt gaggaacggg tgcgcgagga
    38281 agccatttta tacctccagc ataccaattt tatctcagat ggctcagtgc taaatgaatg
    38341 gatctatgga acagtacgaa tgaaggtagg cttaaatcct ggctctggct tcattcatcg
    38401 agctgcaaag gccatccttg gacttcctgg aagaggcttt tataaaaaat acatgaatgc
    38461 ctatgggcag gtggcaaggc tgcattctca gcaatggtac accgatgtcg ttcatcttcc
    38521 tgttgaattt cctatgtcag ctgatgggca taggccagtc tctgagaggt accggacact
    38581 atcagacaaa gaaatcagag aaggctttct ctccattgga aaaacaccag agcttgtcag
    38641 tggtagtcag gtcgagagat tgcgaaaaat cattaaccta tatgacctgc cggttgtcgt
    38701 tccaattgac gaggcagtca ctcaagcaga ggaacaaatc agaaccaaca gagaagctgt
    38761 ctccaagcgg atcattgagc agtataaaga gccttcatta aaagaaaaaa taaaatttat
    38821 atcagaattt taggagtgta gatgatttca tttaagaata ttagcaagac ataccaagtc
    38881 ggagaccaag aggttaaagc attggacgat gtttccttta cgattgaaaa gggaaggttt
    38941 actgttattt taggcccctc tggttcagga aagagcacgc tcttaaattt acttggagga
    39001 atggaccgag caagcaaggg aacctttatc tttgagggta aggacattac agccttaaat
    39061 gataaagcat tatctgatta tcgcaaagag gttgtaggct ttgtctttca gttttacaat
    39121 cttattccaa gcctaacagc cttagaaaat attagtatcg ccgcacagct aaccggaaac
    39181 acagcacaat cagaggtatt gttggataag gtggggttat ctcatcggaa aaacaatttc
    39241 cctagccagc tgtcaggtgg agaaatgcag cgcgtatcca tagccagagc tctggcaaag
    39301 aagccaaaat tattgctatg tgatgagcct accggtgccc ttgattccaa aacagggcag
    39361 cacattatgc agctacttca ggaagcgtca aaggacgagg acgtagcggt tgtcttggtg
    39421 acacataaca ctgaatttaa agcttttggc gataccatta tttacctaaa ggacggaaag
    39481 ataagctcga ttgatcataa acaatcagtt tagaggattg gagctaaaca tgaaatatct
    39541 taatttaaag ctaaggcgag atttaaagca tcattggcag caattctttt cagtgttctt
    39601 gatgtcctta ttaagtgttt taatctttgt tggtctacag ggtgcttggc atgggctgga
    39661 aaaaagctta gacaactata tatctgcctc tcatttgcca accgtttggg tacaggctac
    39721 taatctaaca aaacaggaca ttgaaaaaat agaggcctta aatcaagtca gcagggtcaa
    39781 accaaagatt agggtcactg ctgctattga ttctgacagc gatctagagc attacttaac
    39841 gctagattca ttacagtcta cttcagatca ggtgacacgt gttgtagctg gcgaggcctt
    39901 ttcaaccaaa gaaaccgata aagtatggct gaacaaggaa tatgctgacg ctaaccacct
    39961 atccctcggt gataagatca gcttaacact atcaggtcaa tcaattagtg tgacccttgc
    40021 gggtcttgtc cagtcagcag acaggatcta ctttacaggc agcttagagt atatagcccc
    40081 taattatgat aactatgcct acggctacat ctcaaaaaag agcttagcta agctccttca
    40141 gacgcagctg cctgataata tggttgacat ttacgcctca tctgatgata ttcgagacga
    40201 catagagaac attttaggca ataagctcat ctcttattac aatcaaacaa ccttaactga
    40261 cgtctctgag gcagtcgata gggtaggaca gattagaaat ctctcttact tgttctcctt
    40321 tattttcatc ttactagcta ttctatctat gtttaccact attagacgtc tcatcgaaag
    40381 tcaaacaaag gaaattgcta tcatcaaggc cttaggctat tctaacatac aggtcagtgg
    40441 tcactacatt tcctttggct tgttagttgg aacattaggt gctctttttg gtctgctgat
    40501 atctcctgct atgtcttggt ttgtcctgga gacccaaaag agaatgttct cgcttcctaa
    40561 gtgggaaatt gcttactctt tatcttctct agtggttgct ttactggtgg ttatgatttg
    40621 tgtaacgtct gcttactttg cttctcgaaa agccatcaaa gggctgccag cagtattctt
    40681 acgaggaaaa aacagggacg tcaagcatat tttgctcgaa aaaatcaagc ccttatggcg
    40741 cagtatttct gacgaagcta agtgggctat acgtgacgct ttgacacacc gcatcagaat
    40801 tttaatgggg attatagggg tagctggtag tatgatgctt ttaattgccg gtattggcat
    40861 gcctatctct atgaatcacc ttgttgataa ggcctataac aaggacttta gctactccaa
    40921 acgcttgatg gtttctgact acgaatcggc caataaggcc tataaaggcc aatgggtgca
    40981 aatcaatcaa gcccacttct caaaagatga cggctacaat cgtctcttga ttattatcag
    41041 caagggaagc cttgttaacg ccaccacaga agatggtgac aagataaaag agggtggtct
    41101 ctatgttacc aacagctttg ccaagctagc caatatcaag gttggagaca agctatctgt
    41161 cacaccctac caggataagc atcagtatac ctttagtgtt aagggaattc tgaccagcga
    41221 aactaatcaa ggtgcctata tcatggctga taccttcaaa aaagcaggcg gagcttttca
    41281 cccacacaca ttgttagtag ataagcaagt ttctgcttct acaatcgctc aggatcagaa
    41341 tgttttaacc gtcattgata agtccagcca agaaagcaat gcctatgacc ttgtcaatag
    41401 tctaatgagt gtctttttga tgatcattgg ctttgccttg ctgctagtca tcgttgtgct
    41461 gtataattta ggctccttaa attttgtcga gcgtacaaga gactatgcta cccttcaggt
    41521 actaggattt tcaaaaagaa atctccaaaa tataacaatg ctcgaaaatc tcatgacgac
    41581 ctctgttggc tggctattag gaatccctat gggcatttgg ttcttagagc agtacgtcgc
    41641 aaccttttct acgatacgtc ttgaatatac ggcttatgtc acttggcagg tcctgctagc
    41701 ggcaagtgtc cttgtctggc taacatcatt aatgaccact cttttcatca gtagaaagat
    41761 tagaacaatt gacatggttg atgccttaaa gggagtctac taacctcact ttatcacata
    41821 cctgactctc tcttttatgg ttaagcatca tcactgcacc agttctgata ggaggactga
    41881 taaaacaacc attgtgctgt aacaagcact gtcattacat agcaacaccc ctaaaaagca
    41941 agcatcagat ttggtgcttg tttttgaatt tattgctaat gctaaacgca acgattatca
    42001 caaatcatgc agtacacgct tataacaaag cttaagcatg cccattattc aaaaaacgtt
    42061 gatcaaaatg acttccctga agtttagatc attcctcaat ttattgatac aaacgtgata
    42121 aagtcagacg atcttcttgt taattaaaaa aaaaaacgaa actacggaga gaaagatgag
    42181 ctttgtcgtt tctcacttcc aaccgccatg ttaaaatctt ctctgagaaa gaatgttata
    42241 aaaaagaatc attctatcac caaaggagag aaaaatgata actaaaaaac agagaaaaca
    42301 aaaaagacac acaacaatca gacgcctgtg tcatcaagcc ctagcagcta ccctcatcac
    42361 aggaagcctg atgggaacag gactagttgg aaataaagtc gtgtatgggg atgtgaatag
    42421 tgaaattgaa aaaattaaaa atgtactgaa acaggaatca gataatagca gtaccttaac
    42481 agaaacatta aaag
//
LOCUS       DARYSY010000016        40991 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYSY010000016 DARYSY010000000
VERSION     DARYSY010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40991
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(38..244)
                     /locus_tag="TVR04_000724"
     CDS             complement(38..244)
                     /locus_tag="TVR04_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1269431.1"
                     /translation="MKFSYNKLWKLLIDKGWTKSELRQKAGISSSTIAKLGKGENVTT
                     DILLKICIALDCKIEDIIEIVNSK"
     gene            complement(234..1892)
                     /locus_tag="TVR04_000725"
     CDS             complement(234..1892)
                     /locus_tag="TVR04_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEL1269432.1"
                     /translation="MLIEMWSPVFKKNGQTRKPVRFHPGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYQKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIITYCNDDYSP
                     TGETMPLEIFLNKLKKRYHLDSPNLSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESIITLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYAFISNLVGGKKQFEANVSE
                     IKRLEYDLSHLQDTQQDKIDSGDIEKNQQKIQLRNTKLELENSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLANILDSEFSIERESLIAEIDEL
                     ESQLTILNQELQELGNIPNLSSEYLENYSKLTATINALKEQNEAYLKESSLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMHEFNNILYPDIRKAPQINLKAHNSYSFYTPDDDGT
                     GTKFKGMILFDLTMLYLTNLPALAHDSLLLSNISYQATEALLKLYDQSKSLNKQVFLA
                     FDKASSYSPEANQLLSENTVLRLSSNGNELYGISWNKGENSDEV"
     gene            complement(1883..2107)
                     /locus_tag="TVR04_000726"
     CDS             complement(1883..2107)
                     /locus_tag="TVR04_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269433.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            complement(2107..3225)
                     /locus_tag="TVR04_000727"
     CDS             complement(2107..3225)
                     /locus_tag="TVR04_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269434.1"
                     /translation="MDFPTYFRILKKYLGDGATIPEFFRELIEMITEDDAEEIISASE
                     ITSEKTDSTLVSYAKRGFTKKMANQLICKINSINMKDSIESRPDETIQLLANEFNSYY
                     PDITAKNASLRIPEIFVDFIREKAGMGTATTAQKASFITQSNQLKKQYGQFLLTEANN
                     CCAFPGCDRPLILTRGNLATESYEVSVIEKDKVPEPLNLIALCPDCFLTYQTDNRKKT
                     VASLKNIKKILVSAKNSQQSISDMKLDSGIVSVLTSLNKLKFDEYDISYDPKQLTDKI
                     SPEKNRMLYQMVKNQVIDNYLTIQKIIINLDKQGRIDYEEIQYQMRSMYKKLKAAKHD
                     NLTIFNTISEKLHKATLQDIYFCQMIVSYFIQKCEVLE"
     gene            3658..4254
                     /locus_tag="TVR04_000728"
     CDS             3658..4254
                     /locus_tag="TVR04_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269435.1"
                     /translation="MTNKDNIYNECQKQECSLEVGLLEGQVLAPMLVENQQVIEDMRL
                     KRETLRSWRPAKQLNVYVLVAFIPVFPEEFAKTERIYKDAVENFLNEFRTRKSKNIEE
                     IISYEAWIDMDESTLYSSTEELEEFMFAEMLQDLLEKVKQADKDLYDITLGLLAKEFD
                     ESIEDVFIKIGVKRSTGFYRLPKARALVAALLKELNPK"
     gene            4529..5038
                     /locus_tag="TVR04_000729"
     CDS             4529..5038
                     /locus_tag="TVR04_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="HEL1269436.1"
                     /translation="MHEMKFYQIDTNYLNILRQIDGRVPHNKEFIGRKGKSRPYIGVM
                     LSIDNVDYFVPLSSKKKRSSFVVMPIYDDNDEQIATLMLNNMLPVPPKHRKLLNMDGV
                     RITDPKYFDLLMNELNFLRPRRQAIKSRCTIIRSVKVEGKNKPQINKKTKEFCLNLLE
                     LEEAYKENE"
     gene            complement(5087..7042)
                     /locus_tag="TVR04_000730"
     CDS             complement(5087..7042)
                     /locus_tag="TVR04_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL1269437.1"
                     /translation="MPIIELSIDLETYCEVDLRKSGVYRYAEDDSFEILLLAVSVDNE
                     PVTVYDLTKEELPDEILQALVDDTIIKWAFNASFERICLSNWLKKHHPELLSEGFLSP
                     NSWRCSMVWSAYLGLPLSLEGVGTVLKLKNQKLKEGGDLIRYFCLPCKPTKVNGGRTR
                     NFPNHAPDKWSAFIDYNKRDVEVELAIKEKLRNYPVPVFVWEEYHQDQIINDRGIGID
                     VDFVKGAITIDEESKAKIQEELRELTELDNPNSVLQMIGWLREHGVTTDSLDKKAVKE
                     LLKTVDEKTAQVLKLRQQAAKSSVSKYQAMMNCVCKDGRARGMFQFYGANRTGRWAGR
                     LVQLQNLPQNHLPDLEEARELFKTGDLEATELFYDTQDTLSQLIRTAFIPSKGKKFIV
                     CDFSAIEARVLSHLAGETWRSKVFEQGKDIYCMSASQMFGVPVEKHGQNADLRQKGKI
                     AELACGYGGAVGALKAMGAIDMGLEEQELQPLVDSWRQANPSIVLFWWDVDRAVKTAV
                     KEQIQTETHGIQFEVRNGMLFITLPSGRKLAYVKPKMGENQFGGESVTYEGTGTAKRW
                     ERLESYGPKFVENIVQAISRDILAYSMRQLSEFKIVGHVHDEVIIECDQDQDLEEIST
                     LMGIAPNWMPDITLRADGYECLFYQKD"
     gene            complement(7091..7258)
                     /locus_tag="TVR04_000731"
     CDS             complement(7091..7258)
                     /locus_tag="TVR04_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269438.1"
                     /translation="MTIYYILLSAILGTYVFLGLYLNYMTIRDDIRREKERKAEKKRQ
                     DNNSTPLHRSR"
     gene            complement(7277..7840)
                     /locus_tag="TVR04_000732"
     CDS             complement(7277..7840)
                     /locus_tag="TVR04_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000208945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1269439.1"
                     /translation="MSTKVQTTKVITGKNTRFSYLNANEPKSINGSTPKYSVSLIIPK
                     DDIETVDKIKAAIELAYKEGEAKLKGNGKTVPALSILKTPLRDGDLERPDDDAYRNAY
                     FVNANSPHKPGVVDGNRQEIIDTSELYSGIYGRASISFYAFNSNGNKGIACGLNNLQK
                     LRDGEPLGGRTRAEDDFATDDDDDFLN"
     gene            complement(7845..8966)
                     /locus_tag="TVR04_000733"
     CDS             complement(7845..8966)
                     /locus_tag="TVR04_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001891681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1269440.1"
                     /translation="MTNHAVLSASASHRWLNCPPSVRLTEDMPDVTSEFALEGTDAHE
                     LCAYLVEKALGRKVRDPTKDLSFYNEEMQTCAEEYRNYVMEQVEKAKGYSRDPTVLVE
                     QRLDFSIWVPEGFGTGDCLIVADGLLQVIDYKHGLGVLVDADHNPQMMCYALGALEMF
                     DDLYDFDKVTMTIFQPRKNNISTFEMDKSELLEWAENELSPKAELAFKGEGEMTSGKH
                     CQFCKLKNVCRKRAEDNLALAKMEFADPATLDYEDIAEILPKLDLLVSWANDVKAYAL
                     KEATKGHNIPGYKLVEGRSVRKFSDEAAVTQAVMEAGFDPYEKKLLTITAMSKLLGKK
                     TFNDLLGGLIIKPSGKPTLVPLDDSRQEMNLAKNEFKEV"
     gene            complement(8959..9282)
                     /locus_tag="TVR04_000734"
     CDS             complement(8959..9282)
                     /locus_tag="TVR04_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000077671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269441.1"
                     /translation="MSQHKQLLELITEMEGTAKYYLRLVDEFKKLLSSEEETETTSEE
                     PKPETQKVLKLEDVRAVLATKAKDGYKNEVRALLNKYGAESLSTLANEHYAAVLEEAG
                     GIGND"
     gene            9641..11929
                     /locus_tag="TVR04_000735"
     CDS             9641..11929
                     /locus_tag="TVR04_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1269442.1"
                     /translation="MQFTLSHSGQTGVQTTTVYPHQVTITDKATLQAIAQYDHVAGLF
                     TNNTRSNANFIKSDVLVMDIDNDHTDNSDEWVTEELLKDIFADYNFALVTSRNYLVQK
                     GDKAARPKFHIYFQINEVTDKDTYALLKEELVNRYGIFDTNAKDAARFFFGNPNAKVL
                     WHDSWLTIDEDLLDDMVAQDDEEDFDADFYQPPTGPITEGSRNSTMSVFAAKILKRLG
                     VTKEARDGFDEQALKCVPPLEKAELDTIWGSAVRFYNKTIKNSKDYKSPEEFQRESLK
                     PDDYSDVGEAGVLAREYADKLAYTNATDYLFYDGTHWRENKQLALGAVVNFTDDQLAE
                     ANTFLEVTEKQLQSTGIDEMIIKAGGKRLENAVETSLQLKYLKAYLAAKEFHKFVMKH
                     RDYKNLMAVYNTAKSMLTVELSELDSDDMLLNTPEATYDLRQGTKGQQEHNPEDYITK
                     MTAVSPSDKGQDLWQETLATFFCNDQELIDYVQEIIGMAAIGKVYQEHMIIAYGGGAN
                     GKSTFWNTIARVLGSYSGKLSADALTMSNKRNVSPELAELKGKRLVIASEMAEGMRLN
                     TAVVKQITSTDEIQAEKKYKDPFHFVPSHTLVLYTNHLPKVGANDDGTWRRLVVIPFN
                     AKITGRSDIKNFADHLYDNAAPSILSWIIEGAEKAIKANFKTSVPSAVSNSVKAYREA
                     NDWLGHFLSDCCEVGDQFTEKSGELYSQYRAYCTKNMEYTRSTTDFYSALDQTGFRRK
                     RTNKGNLILGLKLVDDDYDFLD"
     gene            12210..12491
                     /locus_tag="TVR04_000736"
     CDS             12210..12491
                     /locus_tag="TVR04_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1269443.1"
                     /translation="MREKVVEQKLVSEVKKRGGICPKWVSPSFGGVPDRLVFLPKGKF
                     GMVEVKAPGGKPRLLQVTRHRLFERLGFKVHVLDSIEKIGEVLDEIEFT"
     gene            12472..13848
                     /locus_tag="TVR04_000737"
     CDS             12472..13848
                     /locus_tag="TVR04_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1269444.1"
                     /translation="MKLSLHDYQEVTKDFIIRTPYAAVILDMGMGKTATTLSAINELM
                     FDRYEVSKVLVIAPLRVANTVWSDEIDQWEELRHLRYAKIVGTPKQRRAALEQDADIY
                     IVNREILPWLVEQCSPYFKWDMVVIDELSSFKSWQSKRFKAFMAMRPYMKRVVGLTGT
                     PSSNGLMDLFAEFKVIDGGERLGRFIGEYRSRYFEEGRRNGNIVYEYIPMDYAECQIY
                     DKIDDITISMKAMDYLAMPELISTKKLVYLTDKEKSDYKQFKKDYVLSDLEDGEVTAA
                     NAASLSNKLVQMANGAVYSDDYQVVSLHDQKLDVLEDIIEAANGEPVLVAYWFKHDLQ
                     RIEGRLAKLKVKGTVLKTEQDIREWNKGNITVGLLHPASAGHGLNLQKGGHHLVWFGL
                     TWSLELYQQTNARLWRQGQQAETVVIQHIVTEGTIDEEILKALENKDAQQSRLIEAVK
                     AQVGGTDG"
     gene            13841..14317
                     /locus_tag="TVR04_000738"
     CDS             13841..14317
                     /locus_tag="TVR04_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269445.1"
                     /translation="MDKAEYILTHYNELKGDLEMLQYRLENFKPVTENEVIGSLVFER
                     SDEPKVTSTPANLRSEVIALSFRDKMIQENEELLADLTQRYIRLANDLDNFEMAIRFL
                     KDDLAEFAQEMLKPECNWDSLMREFHISRSTVRNWRRKVLDHVRGVYLKMGYSLEK"
     gene            14512..14694
                     /locus_tag="TVR04_000739"
     CDS             14512..14694
                     /locus_tag="TVR04_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269446.1"
                     /translation="MTKRQQEKLNALLTAIAQEELLVETLETRKSDNLDFYDVSVWGV
                     KRALERSYEAGQQSVK"
     gene            14742..15779
                     /locus_tag="TVR04_000740"
     CDS             14742..15779
                     /locus_tag="TVR04_000740"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1269447.1"
                     /translation="MIFTSEQVSSGHPDKLCDQISDAIVTECLKHDKNSRVAVETLIK
                     DNQVVVAGEVSTKHFFNLEGIVKKVLEPYGMDDVMVTNVLGVQSPDIAQGVDKGGAGD
                     QGIMFGYATDETPEFLPLPYVLATRVLEKLTNLGHPALGKDAKAQVTYDYENKRIETF
                     LVSIQHDEEVDLAFVKRIVTQTMMSVAQRYRQNLDFRVLVNPTGRFVLGGSYADAGVT
                     GRKIVADTYGGFAHHGGGAFSGKDPSKVDRSATYMARKIAKDFVREGYAKRCEVQLAY
                     AIGVTEPVGVYVNTFGTSDYTLEQLVGVVRERYDLTPQGIIKDLNLLDVDYTKTTCLG
                     HFTKPYLPWEQ"
     gene            15781..16146
                     /locus_tag="TVR04_000741"
     CDS             15781..16146
                     /locus_tag="TVR04_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1269448.1"
                     /translation="MPRRPSTACKQHGCPNLVTYGNKYCDDHKANHTLDAKSTKAKGY
                     NSRWNKARLRYLKLHPLCVYCQRKGRLTKATVVDHVTPHRGDQDLFWNQSNWQALCKS
                     CHDRKTKTTDRYVEYTYRF"
     gene            16434..16888
                     /locus_tag="TVR04_000742"
                     /pseudo
     CDS             16434..16888
                     /locus_tag="TVR04_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004990.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            16860..18116
                     /locus_tag="TVR04_000743"
     CDS             16860..18116
                     /locus_tag="TVR04_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA modification methylase"
                     /protein_id="HEL1269449.1"
                     /translation="MTNQPTMEIKELLLTELQPASYNPRKQLKKGDKEYEKIKQSLLK
                     FGYVDPIIVNKDLTVIGGHQRLTVLKDLKYETAKCVIVSLSKEDEKALNIALNKITGQ
                     WDDQLLADLLLDLQESDFNLDLTGFEPPEIDDILSNIHDKDLSEDDFDVEEELKKPTV
                     ARQGDIWQLGKHRVICGDSTKAETYDQLLGNKKANLVVTDPPYNVDVEETAGKILNDN
                     MSDGDFYQFLYNMFSQVESHMEADASIYVFHADTEGLNFRKAFKDAGFYLSGCCIWKK
                     NSLVLGRSPYQWQHEPCLFGWKQKGKHQWFSDRKQTTIWEYDRPKSSKDHPTMKPVQL
                     MAYPIQNSSMRGTLVLDPFLGSGSTLMAAEQTGRICYGIELDEKFVDVIVKRYMEATG
                     NTTVTVVRDGQTLTYDEAVSAMEEGL"
     gene            18146..18472
                     /locus_tag="TVR04_000744"
                     /pseudo
     CDS             18146..18472
                     /locus_tag="TVR04_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176344.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            18534..18785
                     /locus_tag="TVR04_000745"
     CDS             18534..18785
                     /locus_tag="TVR04_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269450.1"
                     /translation="MKTTTLERLYSYHQATASIIPYKDWVIVAYSGYKGVSVDIYEST
                     DSLEDFSNFERRFDRIYQEEGNFQDQGHAVKWAFETIGV"
     gene            18787..18996
                     /locus_tag="TVR04_000746"
     CDS             18787..18996
                     /locus_tag="TVR04_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4314 domain-containing protein"
                     /protein_id="HEL1269451.1"
                     /translation="MNDKILNRIKFTYPKGTRVRLIQMDDPRPVPVGTLGTVLDVDDL
                     GSLIVSWDNGQSLNVLYGIDSVEKI"
     gene            19045..19518
                     /locus_tag="TVR04_000747"
     CDS             19045..19518
                     /locus_tag="TVR04_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1269452.1"
                     /translation="MAVRGRKPKPTNLKILEGNPGKRPLPTNEVKPRQKAPRCPQWLE
                     DDAKKEWKRMGKILEQMGILTEMDMTAFAGYCQAYARWKEAEEFLSKHGSIIKTPNGY
                     LQQVPQVSISQTNLKIMLKFCEQFGLTPSARNRLATMDSEVGTGDEMEDLLGGIL"
     gene            19515..21107
                     /locus_tag="TVR04_000748"
     CDS             19515..21107
                     /locus_tag="TVR04_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1269453.1"
                     /translation="MTYHYEPSPFMLPTSRYDKAKADRAVTFINNLAHTKGKWAGKKF
                     DLLPWQEQIVRDLFGIVKEDGNRQFLTAYIEIPKKNGKSELAAAIALYLLYADNEASA
                     EVYGAACDRNQASIVFDVAKQMVQMSRPLEKRSKIMGATKRIVNYSNAGFYQVLSAET
                     GTKHGLNVSGLVFDEIHAQPNRHLYDVLTKGSGDAREQPLFFIITTAGTDKNSICYAL
                     HTKALDILKGRKKDTSFYPVVYGLSDEDDWNDEANWLKANPSLGHTIGLDRVREAYQQ
                     ALDNPAEENVFKQLRLNMWTSSSVAWIPEHVYAKGDAPIDYNSLKGRDCYAGLDLSST
                     SDITAFVLVFPPRYEEENYIILPFFWLPEDTLSLRIRRDHVLYDVWERQGYIHTTEGN
                     VVHYGYIEKVIEDLSKTYHIKEIAYDRWNATQMVQNLEGIGLTMVPFGQGYKDMSPPS
                     KELYKLMIEGKVQHGGHPVLKWMGQNVVMRQDPAGNIKPDKEKSVEKIDGIVALIMGL
                     DRCIRHQGNEGSVYDERGILSF"
     gene            21211..21561
                     /locus_tag="TVR04_000749"
     CDS             21211..21561
                     /locus_tag="TVR04_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269454.1"
                     /translation="MATNARIGLLTKSNTATFIKAAYEGYPSYTGSLLTSAFNSLKQV
                     KELLKKGNIIMLEENLDEVETDSLVKVTENIRFVGSESDLEGDYLADYTYVYKETEKR
                     WYILTDGKLVPCYL"
     gene            21619..22908
                     /locus_tag="TVR04_000750"
     CDS             21619..22908
                     /locus_tag="TVR04_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1269455.1"
                     /translation="MGILDWIGSKRSRDKPHNSYEGQDFSYLFGRTTSGETVDEFKAM
                     QTTAVYACVRILAEAVASLPIHVYERTETGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TMMSHLLIWGNAYVQIIRDKGGRVISLYPLLPDKMSVHRDDSGRLYYKYQRQTEENPN
                     FNDKGTVLLKQEDILHVPGLGFDGLIGYSPIAMAKNAIGMTLATENYGASFFKNGANP
                     GGVLEHPGILKDPKRVRDSWNAVYNGVTNAHKVAVLEEGMKYTQVGIPPEEAQFLQTR
                     KFQINEIARLYRIPPHMVGDLEKSSFSNIEQQSLEFVKYTLDPWVVRLEQAFKRSLFL
                     PEEKKQYFVKFNVDSLLRGDYQSRMNGYAIARQNGWLSTNDIRELEDLNLLSDEEGGN
                     LYLINGNMTKLEDAGGFMKQPTETEPTEHAIEEEENA"
     gene            22901..23599
                     /locus_tag="TVR04_000751"
     CDS             22901..23599
                     /locus_tag="TVR04_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1269456.1"
                     /translation="MRKFWNFTDEGGARTLRIEGQIADETWFGDEVTPQLFKNDLLAG
                     KGDITLWINSPGGDVFAAAQIYNMLMDYQGDVNVIIDGLAASAASVIAMAGTTVSMSP
                     VAMMMIHNPWTMAQGEAKDMAKVIEMLGEIKESIINAYELRTNLSRTKISHLMDSESW
                     FNAKKAVELGFADKVLFEKEEASKQGSQNSYTFSRVTAVHDLVVKLQASVQPSKPEKT
                     IPFNQLEKRLNLLK"
     gene            23613..24818
                     /locus_tag="TVR04_000752"
     CDS             23613..24818
                     /locus_tag="TVR04_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1269457.1"
                     /translation="MSKLLELKEKRNKAWQDAKAFLDACETADGMVSEADAKRYDDME
                     TKVTNLNKQIERLERQEKLDLELSQPTSQALTTQPTVIVDKENEDDKKGIASDVYSQT
                     FWTNVRKRHFFDVKDVLRVGEDTEGGHLVPDEYEKKLVQGLQEENFFRGLATVIKTSS
                     GERKIPVVTGHGSASWMDENGLYPETDETFGQVTLDSHKIGTAIRISEELLNDSVFDL
                     ESYMIAEFARRIGTEEEKSFLIGDGSKKPTGIFTQAEVTGPTTATKDITFDDMIELYH
                     SLPAPYRKNAVWILHDTTVKAIRKLKDNNGNYIWQPSTQAGQPDLILNRPYYTSTFAP
                     LPEAGNKAIAFGDFSYYWIADRQGRTFKRLNELYANNGQIGFLASQRVDGKLVLPEAV
                     KVLTVKGKG"
     gene            24818..25075
                     /locus_tag="TVR04_000753"
     CDS             24818..25075
                     /locus_tag="TVR04_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEL1269458.1"
                     /translation="MITLEEAKLYLKIDNDDEDELILALIRSSKSLCFDIQRHEESSE
                     LLKTAILYGVAFLYEHRELANHKELKETLYHLLLADRKDVF"
     gene            25075..25413
                     /locus_tag="TVR04_000754"
     CDS             25075..25413
                     /locus_tag="TVR04_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HEL1269459.1"
                     /translation="MKIAPLREQLVFQEKQIKQDEIGNESAIWDDLFVRWCSCRPLAL
                     TESDGSAIKLIHHKIQFTLRYDKKVLALNSLTTRISFRDQFYAIESIDGDTVPRQLIY
                     IVAIKEEDHD"
     gene            25406..25774
                     /locus_tag="TVR04_000755"
     CDS             25406..25774
                     /locus_tag="TVR04_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1269460.1"
                     /translation="MTRIGLDDLVSVVENELTTYAKETTDTMREVVEEVTDEAVETLK
                     VTSPKRRGKYARGWKSKTTTDTNTALTKTIHNGTPGLTHLLEDGHAKQNGGRVKGRKH
                     IAPVEKKAIASFEDKLRQKL"
     gene            25783..26109
                     /locus_tag="TVR04_000756"
     CDS             25783..26109
                     /locus_tag="TVR04_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269461.1"
                     /translation="MQFKDLFSVLKETKLSVAYHHFEEGHSPSPPFMVYLVTDSDNFG
                     ADNWNYHKRLNVQIELYTTKKDLATEKTVESVLDAHRLYFDKVETYITSEKLYQTIYS
                     ITLLGG"
     gene            26112..26681
                     /locus_tag="TVR04_000757"
     CDS             26112..26681
                     /locus_tag="TVR04_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1269462.1"
                     /translation="MTEKNKVTFGLQDVHWAEVTSEGADGALTYGNVERLRGAAELTL
                     EPTGDKGSYKADNINFYTSESNDGYEGTLKVALLSQEFLTRVLGEKLDATTNTISEIA
                     NSEKKNFALMFRFEGDKKETLHVLYYCYASRPTVGSKTKSGSDINEVELTFTASPRPL
                     DKIVRRRTTEETSDEIRENWFKSVFEPTT"
     gene            26693..27112
                     /locus_tag="TVR04_000758"
     CDS             26693..27112
                     /locus_tag="TVR04_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269463.1"
                     /translation="MRQNITIAGKTYPLATNAYTPIAYKEQFGKDYFQDLFNMLSAES
                     IMAQLEQLEEGEELKASQIDLSILSDFDMTFFHRLFWVFAKSANPRIKPFEDFFMSME
                     EFPLQEVGPVLMSMLNQGMTTRKKQMTHKQRVRKSSR"
     gene            27295..30414
                     /locus_tag="TVR04_000759"
     CDS             27295..30414
                     /locus_tag="TVR04_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1269464.1"
                     /translation="MAGSIKGITIEIGGDTQPLQNALKGVNKQASEATKELRQIDKAL
                     KFDTGNVTLLTQKQEVLAKQVETTKEKLATLRQAQAQVEAQFKAGNIGADQYRAFQRE
                     VESTQTVLKGYESKLESVNKALSDNGTQVESNRSKLNSLQNEQAQLVSESEKLNSSFK
                     LQESALGSTASEADKLALAEQKVASHSEILEKQIHNLEQQLSLTKSEYGENSIEANKL
                     EKKLNETKTAYNNLQNEMEELASSSASSKASLEETNSLLKADLLMEFGDQLGELSQKL
                     IDFGQQSLDAFLEVDEGMDIIVTKTGATGSALEEMTDIAKTLATELPTDFNTAGSAVG
                     ELNTQFGLTGDALKSASTQLIQFSEINGSDVTSSAISAKQAIEAYGLEATDLSSVLDT
                     VTYTSQATGVGVQELMDKAVAGAPQIKALGLSFDEGVTLMGQFEKAGVDSSAALSSLS
                     KAAVKYAGDGLTLQEGLAGTIEQIKASTSETMALSLASEIFGSKAAPRMVDAIKRGAL
                     SFEDLAGTADKAAGIVTQTYEGTLDPIDKFTTAQNTAKLAMAEMGDAIAATLAPILEV
                     LASLLQAVATWFSGLSEPVKQFIVIVGSLVAALGLVLPIFIALQAAAMAMGTTIMGMI
                     TAAAPIVGIILGVIAAIALLVVGIQQLWQHHEGFRTAVTEIWNAIFAFLSVIIQQISS
                     FVMSIWGTLTTWWTENQQLILNSANTVWTAISTVIQTIMTILGPYLQASWENIKLIIT
                     TAWDIIKVVVETAINVVLGIIKAVMQIITGNWSGAWETIKQVVSTVWEAIKSLISIVL
                     NAIAQFISNSWNGIKGTMTNLLNSIKSVVSNVWNGIKSTISSILSSISSTVSSIWNGM
                     KATISGVLSGISSTVSSVWNGVKSTITNAINGAKNAVSSAINAIKNLFNFKIKWPHIP
                     LPHFSVSGSANPLDWLKGGLPKISIQWYAKGGILTKPTVFGMTGNSLMVGGEAGREAV
                     LPLNNQTLGSIGRSIAATMPNKGTSITVNITDVVIREEADMKKLADYVAGRLADEMTR
                     QALLRGGTV"
     gene            30411..31136
                     /locus_tag="TVR04_000760"
     CDS             30411..31136
                     /locus_tag="TVR04_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1269465.1"
                     /translation="MIKHNELVLNGKGTSSFPFKVLVEDRPSIQVPRSKTQLLDHRGL
                     SGVIVQTNKHRDVIEKSYRLYLIGASEKEVNEFAAFLMQEGFWLESERLKLTRLWCYR
                     TDSFDIKQDEHDVFVIDVTFICHPTRFFNSVDRQVLSTNGVLKTQGSALAFPTITITG
                     QSVSETSFTVGDQVIRIEKFTEPLVMVNQPDRPSFKTLSGKAVKWSGDFITIDASHPT
                     HSVGVVLGSGILSLTFETNWGWV"
     gene            31136..34051
                     /locus_tag="TVR04_000761"
     CDS             31136..34051
                     /locus_tag="TVR04_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1269466.1"
                     /translation="MLYLLGGQTKTPKWNGQPLFETVSATVEEELNSTFQLHLTYPIT
                     DSGIHETLRADELILCPTPDLGKQLFRVKQVKIQDDTIELECYHISDDMMKRQIKPFS
                     ATNTTCQSALMRLVEACPSDLGLFSFDSDVTERHTYVSDEDLTLYQALMDGKHSILGT
                     WEGELVRDNFQLIVKQHRGKDKGVILTSHHNLKAFGDKGDSEKVITRIYATSTFQAEG
                     SDEDTVLSVVVESPLINQYPYVHEARYDNNTLQTEEELRQWAMAKFTHEHIDHISRQL
                     TVEAYQLDGQEVHLGDTVTLKSQKHKVDVKKKAVSYTFDALEEVYLSVTFDDEVSFTR
                     SGSSGNNSLTSAAKTILDVNQSATEHRASKERANFNKVFDRHFERLQTEVEDGIAKAK
                     AEGERSGKKAALDYLATDALEARVAALQKATIDELTVSSSAWMTRLVSQQILSEYVKS
                     LEIEADKVVIPGQHTPVFSLDRDGSLSIDTPLLKVRGESLATKVDLKTISLTPGPKGD
                     AGADGVGIQLREQYYLVSAQKTGITTTSSGWSKTIPSLTSTLKYLWNYEKTTFTNGST
                     TVTTPIVIGVYGDKGMDGKAGKDGKTLYTWRMYADSDKGDGISAVSTGKRYLGLAVNR
                     ESATPSTNPGDYIWSSFFEGTELGGRNYIDDYAMKAVTFSSVTSEWKKEVIEDTSSVS
                     GVTIKLICTKAGTGGFHRNFYDLRSRIGATMTFSIDIKCSKSVTLNMGCELGGTKAYE
                     VTTDWQRFVSSWKVSSYQYYSYIFYLKSGSWSVGDVVYLRNVQLEDGNVASAPGPSLN
                     DLIAQIDTKADNGFMKQQLDLLTEKTESLRVDLEARALAKEVADWLKSYKEFEKNNEA
                     VLTQFNQDFIDNTARIAAIEADLKANSLLLNFVNTYLRAGDNGVIIGKKDNSEYIELT
                     PQGMMIKSAGNAVMTVTAGVIKIHHGVFVETLQVGYYRLEAARHNAKHLVCRFIDAK"
     gene            34064..35920
                     /locus_tag="TVR04_000762"
     CDS             34064..35920
                     /locus_tag="TVR04_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269467.1"
                     /translation="MADYGSNNDRGYTLLLRVEETGTSTANNTSTVRVQLWLKNGYTT
                     FGMYDCRASVSINGQTLSWSGRPDMYTAHSSLHLIDKTITVSHDSNGSKTISFSATFS
                     GSGGWSPGTLNTGSQTLRLSDIPRSSSATVSGNMMGQAVTITIKRASSDFTHNITWHF
                     GSLSGTIATGIATSVTWTPSISQLATQIPNSTSGNGHLTLATIYGGKTIGSMTIPITL
                     NLPTSVVPTLGNISVSESHATAKTILTGTSFAQLVSNPKVTFNQGVGVYGSTIPSTGF
                     RAEVFKFENNQWVQLPNVATSNNGLLGGINWIGRAKVSAYVTDSRGRQSARKEVEITL
                     LEYFKPIFSFSAVRAGSSMNQVTVTRKLKIAPLTISNVQKNKATLTWEVVDLATGQKV
                     TNAGGAANWTSTTEHTKTAFQAILGDTYDTTKSYTIIGILADVFYSTTFEFTIGPEKV
                     VYGLSPSGMGIGKAWTRGVLDVDGSLPAYFDGEIYMKNKKLLDIFYPVGVIYESTSST
                     SPATIMGGTWERFGNGRVLVGVSENESEFNSINKSGGSKTHTLTIDEMPSHSHAQYVS
                     ANNGNQAIRRDYSSDGNSSLYPQGNNTGNTGGNKPHNNLQPYVTVYRWRRTA"
     gene            35938..36342
                     /locus_tag="TVR04_000763"
     CDS             35938..36342
                     /locus_tag="TVR04_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1269468.1"
                     /translation="MKELLATNKVLFSAIGGLIGSIFGEVDGVLYALFIFLIIDYVTG
                     FFAAVVEKNLSSSIGFKGIFKKIAILFLVSVGHLIDTEIIKQGGAIRTMVIFFYLSNE
                     GLSILENVVRIGLPIPEKLQTLLKQFNEKEGD"
     gene            36344..37813
                     /locus_tag="TVR04_000764"
     CDS             36344..37813
                     /locus_tag="TVR04_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEL1269469.1"
                     /translation="MGKHLVICGHGQGRTAYDPGAINSKRGITEAGKVRELAKLMSKY
                     SGKSIDYITDQNVYDYQSLASLGKGYDSITELHFNAFNGTARGTEVLIQSSLTADQED
                     EAILTVLAKYFPNRGIKKVDWLYNANVAKERGYTYRLVEIAFIDNEADMTIFETKKEE
                     IAKGLVSAITKQEVATSTLQPPSQQPNPSTSDSTSVDYLIGGHVRVLPHATHYQTGQA
                     IATWVKGKTYTIVQKKTVKQSRSTKAYLLSGIQSWVLEQDLEVIQTIHSEQTYRAQKG
                     DTYYGIAKRFGLSLDQLLLVNGLKKTDVLKIGQTLKVHPSSKTITSIPTSVAQRVVAS
                     ALSKVGQKVTVPTNPYGGQCVSLVDKIVQEVTDKNMAYTNAIDCLTKAKDNGFTVIQD
                     AWGVNPKAGDFYVIDTIGMPYGHIGICISDSDGTSIDGVEQNVDGYSDNNKNGINDQL
                     EIGGGGITRRVKRVWMADGSIYDASGTVKLGKVIGWFRV"
     gene            37932..38075
                     /locus_tag="TVR04_000765"
     CDS             37932..38075
                     /locus_tag="TVR04_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1269470.1"
                     /translation="MHQNLTERREHFLTAFEVVQTILGFGSFTISLIGLCYKIFKDDD
                     KKK"
     gene            38452..39693
                     /locus_tag="TVR04_000766"
     CDS             38452..39693
                     /locus_tag="TVR04_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1269471.1"
                     /translation="MTVKLIKAKHTPKKQRVCAYVRVSTTNSSQLDSLENQIAYFTNL
                     YGNRDDVTFVGVYHDKGISGSTDYRPSFQAMIEDCRKGQIDLIHTKSISRFARSTMTI
                     LEVSRELKVFGVGIYFEEQNINTLSSEGEVMLSVLASLAEEELESMSANQRWAFQKKF
                     QRGEMVINTKRFMGYDVDDKGELVINEEEALVVRRIFHLYLDGMGLHRIAKQLNHEKV
                     PTVTGAKWYDTTIRNILRNEKYKGSVLLQKYFHDGVNGKKRLNQGQVEQYLIEDNHEA
                     IISKDDWQVVQEKLNQNSRNQGPNKIYRFTGLLKCQYCSSTLKRQVSYKGKIVWCCSK
                     YIKEGKISCQGMRVPENDINDWQIQTAVTVIERIEDGQKHYSYSSKEGTGNNATPYQR
                     ENQSSRLLSGVHRPRRTAIKL"
     gene            39632..40948
                     /locus_tag="TVR04_000767"
     CDS             39632..40948
                     /locus_tag="TVR04_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1269472.1"
                     /translation="MRVAAYCRVSTDQDEQLSSYENQVRYYRDYILKHEDYELVDIYA
                     DEGISATNTKKRDAFNRLIQDCRAGKVDRILVKSISRFARNTLDCIKYVRELKELSVG
                     VTFEKENIDSLDSKGEVLLTILSSLAQDESRSISENATWGIRKKFERGEVRVNTTKFM
                     GYDKDENGRLIINPVQAETVKFIYEKFLEGYSPESIAKYLNDNEIPGWTGKANWYPSA
                     IQKMLQNEKYKGDALLQKTFTVDFLTKKRVQNDGQVNQYYVENSHEAIIDKDTWELVQ
                     MELTRRRDFREEHQLKAYIMQNDVNPFTTKVFCAECGSAFGRKNWTTSRGKRKVWQCN
                     NRYRVKGQIGCQNNHIDEETLEKAVVMAVELLSENVDLLHRKWNKILEENRPLEKHYS
                     SKLAEMINKPSWEFDSYEMCQVVDSITIAEAGQITVRFLEGTDVDL"
BASE COUNT        12124 a         7862 c         9338 g        11667 t
ORIGIN      
        1 gattattgat tctgtgctgt ttgatagcta actattacta tttactattt acaatttcta
       61 taatgtcctc aatcttgcaa tcaagtgcaa tacaaatttt caataaaata tcggtcgtga
      121 cattctctcc ttttcctagc tttgcgatgg tggaagaact gattcctgct ttttggcgaa
      181 gttctgattt agtccatcct ttatcaatta acaacttcca taatttattg tagctaaact
      241 tcatctgagt tttctccttt attccatgaa ataccgtaga gttcatttcc gttgctagag
      301 agtctcaaca cagtattttc tgacaagagt tgattagctt ctggagaata agagctagct
      361 ttatcaaagg ctaaaaagac ttgtttgttc aatgactttg attgatcata cagcttcaaa
      421 agtgcctcag tcgcctggta gctaatatta ctcaagagta atgagtcgtg tgcaagtgct
      481 ggcaggttgg tgagatagag catggttagg tcaaataaaa tcatcccttt gaacttagtt
      541 cctgtaccat catcatctgg tgtatagaag gagtagctat tgtgagcttt gaggttaatt
      601 tgcggagctt tgcgaatatc tggatacaga atgttattga attcatgcat cttgctattg
      661 atttttactt ctaaatccag aaggatatct tctgtactgc gtttcaagtc agcgtcggct
      721 tcagattttt ctttggatag actagattcc tttaagtagg cctcattttg ttctttcagt
      781 gcattgattg tagctgttag tttagagtag ttttctaagt actcacttga aagatttggg
      841 atatttccta gttcttgaag ttcttggttt agaattgtta attgactctc taattcgtcg
      901 atttcagcta ttagggattc acgttcgatt gagaattcgg aatctaaaat attggccaat
      961 tttttatgat aggcttcaac ttcatataat tttttgagat tagtatctgg gaagtattgt
     1021 tgaagctctg ttaagtcaga ttcagttgga tataagccaa attcgatact gatgtccaat
     1081 agcttaaggc gtctttgctt atctctaaga ctgttctcta gctccagctt agtatttcta
     1141 agttggattt tttgttgatt tttctcaata tcaccagagt caattttatc ttgctgagta
     1201 tcttggagat gtgataaatc atattccaat ctttttattt ctgagacatt cgcttcaaat
     1261 tgctttttac cgccaaccag gttggagatg aaggcatact ttcgagcatt acggaatgtt
     1321 gtgagctggt cgctcttatc ctttaaccgt tctttgtatc gtgcaatgtt atcatacaga
     1381 ttaaaaagct ggataagagt gataatagat tctgaagatt tttggctcga ataaacttgt
     1441 agagggaaat cagtattttg attacttttt cctgcaattc taaagaatcc actcatagct
     1501 aatcgaaatg atagatttgg agaatctaaa tgatatcgct tcttaagttt gttcagaaag
     1561 atttctaggg gcattgtttc accagtagga gaataatcat cgttacaata tgtaatgatg
     1621 tctggatttg ctgtatctct tgagaaataa aactttttct caaattgaaa gcagaagtag
     1681 ataggatggt cacctaattt cttaacagcg atagattttt gataactatt gcctccaaag
     1741 atgaaatcaa tggctaatag tgaggaggat tttccgatag agttatcagc taaatccatc
     1801 cccataatca catttaatcc aggatgaaat cgaactggtt tccgagtttg cccattcttc
     1861 ttaaagacgg gcgaccacat ttctataagc ataattttac ctctccttca ttagacattt
     1921 caatggcgtt caatgcatac aagcaatcca ttatggatag gaaatctgta ggatcatcca
     1981 actcttctga gatagcgtga aagatatcct tgacgtttga gtttccactt ttgatttcat
     2041 ttagcactct aggcaaataa gctagggtgc ttttttggta ggaataaagt ttatttggta
     2101 attgcattat tcaagaacct cgcatttttg gataaagtaa gagacaatca tctggcagaa
     2161 gtagatgtcc tgtagtgtag ctttatggag tttttctgaa atagtattga aaatagtcag
     2221 attatcatgc ttggcagcct ttaacttttt gtacatcgat cgcatttgat attggatttc
     2281 ctcgtaatcg attcttcctt gtttatctaa atttataatg attttttgaa tggttaagta
     2341 gttatcaata acttggtttt taaccatttg ataaagcata cgatttttct caggtgatat
     2401 cttatcagtc aattgcttcg ggtcatagga gatatcatat tcatcaaatt ttagtttatt
     2461 gagactagtc aaaactgaaa caattccact gtctaacttc atatcagaaa tcgattgttg
     2521 gctgttcttt gctgaaacta gaattttttt gatattttta agcgatgcta ccgttttttt
     2581 acgattatct gtttgatagg ttaaaaaaca atctggacat agggctatta agtttagcgg
     2641 ctcaggtacc ttatcttttt ctattacaga aacctcatag ctttctgtgg ctaagttgcc
     2701 ccttgttaga atgagtggtc tgtcacaacc tggaaaggca caacagttat tggcttctgt
     2761 caataaaaat tgtccgtatt gttttttgag ttgattagat tgggttatga atgaagcttt
     2821 ctgcgctgtg gttgctgttc ccatcccagc tttctctcta atgaaatcaa cgaaaatttc
     2881 tggaattctt agtgaggcat ttttagcagt aatatcagga taataagaat taaattcatt
     2941 ggctagcaac tgaatagttt catctggtct actttcaata gagtccttca tattaattga
     3001 gttgatttta cagatcagtt gatttgccat cttcttggtg aagcctcttt tggcatagga
     3061 aactagtgta ctatctgttt tttctgatgt aatttcagaa gcactgatga tttcttctgc
     3121 atcatcttca gtaatcattt caatgagttc tcgaaaaaac tctggtatag tcgcgccatc
     3181 tccaagatat tttttcagaa ttctaaaata agtgggaaaa tccaagtgat gttctccttt
     3241 tcatttttgt accaagttgt accgtactgt actaaactgt cccttaattc aaaatctcat
     3301 ttaatacaat agagtcgaac aaagtaatcg ttaatgatta cctttattat atcatgacag
     3361 gattgcgatg ttcaaaaata tatttgcgaa cgcataaaaa attttgcgaa tgtaaaaaat
     3421 cttgattatc gaatagcgct aataggtaat ttgagaccgt tgttgcctaa tgatgatact
     3481 ttgtaaatga gtgaaactga tttaccgtga ctttaagggt acaaattagg tgtgcagttc
     3541 agcttgtaaa gtcagttgac catgaattag cagaggaatt gctgatgtgg tcagaaaatc
     3601 tttttaatag ttctttgtct tgtcacgttt ctctgcttaa gacagaaagt ggaaaacatg
     3661 acaaacaagg acaatattta taacgaatgt caaaaacaag aatgctccct agaagtcgga
     3721 cttttagagg ggcaggtgct agctcctatg ttggttgaga accaacaagt tattgaggat
     3781 atgcgtctca aaagagagac ccttcggtct tggaggccag ctaaacagct gaatgtttat
     3841 gtactggttg cttttatccc agtctttcct gaagaatttg ctaaaacgga acgtatctat
     3901 aaagatgccg ttgaaaactt tttgaatgag ttccgtacac gtaagtcaaa gaatattgaa
     3961 gagattatct catatgaagc ctggattgat atggatgaat ctactcttta cagttctact
     4021 gaagaattgg aagaatttat gtttgcagaa atgctacaag atttacttga gaaagtaaaa
     4081 caggccgata aggatttgta tgatatcact ttgggcttac tcgccaaaga gtttgatgag
     4141 agcattgagg atgtgtttat taagattggg gtgaaacgtt ctacaggttt ctatcgtctg
     4201 ccaaaggctc gtgctttagt ggcggcttta ttgaaagaat taaatcccaa atagggtata
     4261 tatttgacac cagcgatgtt tttggtataa tttaagtaga ggtagtcgga gagtagtacc
     4321 gactctaaaa agaaaatact cattcggaga ttccgcgcct tactggaagt tttaattttg
     4381 gagattccgc gccttactgg aagttttaat tttggagatt ccgcgcctta ctggaagttt
     4441 taattttgga gattccgcgc cttactggaa attttaaaag ggttgtcgac gggcaaccct
     4501 atttttttaa gtgagtgtaa tatcaactat gcatgaaatg aaattttatc aaattgatac
     4561 taattatctg aatatactcc gtcaaattga tggaagagtt ccgcataata aagaatttat
     4621 tggtcgaaaa ggaaaatcta gaccatatat tggtgtgatg ttgtctattg ataatgttga
     4681 ttattttgtt cctttgagtt ctaaaaagaa gcggtcttca tttgtagtta tgccgattta
     4741 cgatgataat gacgaacaga tagcgacatt gatgttaaat aatatgctgc ctgtacctcc
     4801 aaaacacaga aaattattga atatggatgg tgtaagaata acagacccga agtattttga
     4861 tttgttgatg aatgaattga acttcttacg tcctagaaga caggctataa aatcaagatg
     4921 taccatcatt cgctctgtta aggttgaagg aaaaaataag ccgcagataa ataagaaaac
     4981 aaaagaattc tgcctaaatc ttcttgagct agaagaggcg tataaggaaa atgaataact
     5041 aaaacggttc attaccatat attgggtagt gaaccgtttt ttgtgtctag tccttctgat
     5101 agaagaggca ttcataacca tctgcacgaa gagtgatgtc aggcatccag ttgggtgcaa
     5161 tccccatcaa ggttgaaatt tcttcaaggt cttggtcttg atcacactca atgatgactt
     5221 catcatggac atgaccgaca atcttgaact cactaagttg tctcatcgag taggcaagaa
     5281 tatcacggct aatggcctgg acaatgttct cgacaaactt tggtccatag ctttcaagtc
     5341 gctcccaacg tttagcagtt cctgtacctt cataggtgac agactctcca ccaaattggt
     5401 tctcacccat cttgggtttg acgtaggcaa gttttcgacc agaagggaga gtgataaata
     5461 acatcccatt tctgacttcg aactgaatgc cgtgagtttc ggtttggatt tgttctttga
     5521 cggcagtttt cacagcccta tccacatccc accaaaaaag gacgatgctg ggattggctt
     5581 gtcgccagga atccactagt ggttggagtt cttgttcctc aagtcccata tcaatggcgc
     5641 ccattgcttt aagagcacca actgctccgc catagccaca ggccaactcc gcaatcttcc
     5701 ctttttgacg taggtctgca ttttgaccat gtttctcaac tggcacaccg aacatttgtg
     5761 acgcagacat acagtagata tccttacctt gttcaaagac cttgctccgc catgtctctc
     5821 ctgcaagatg agacagaaca cgcgcctcga tggcagagaa gtcacacaca atgaacttct
     5881 tacccttact tggaataaaa gcagtgcgga taagttgtga cagggtatct tgcgtatcgt
     5941 agaaaagttc agtagcctct aagtccccag ttttgaagag ttctcttgct tcttcaagat
     6001 caggaagatg gttctgtggg aggttctgta gttgcaccaa tctaccagcc cagcgaccag
     6061 ttcggttagc tccgtagaat tggaacattc ctctagcacg tccatcctta caaacgcagt
     6121 tcatcatggc ttgatattta gaaacactgg atttggcggc ttgctgccga agtttgagaa
     6181 cttgtgcagt tttctcatca accgttttga ggagttcttt cacagctttt ttgtccagtg
     6241 aatcggtggt cactccgtgt tctcttaacc aaccaatcat ctgaagaacg gagttgggat
     6301 tatcaagttc agttagttct ctcaattcct cttggatttt agctttactt tcctcgtcaa
     6361 tggtaatcgc acctttaacg aaatctacat caatcccaat cccacggtcg ttgatgattt
     6421 ggtcttgatg gtattcctcc caaacaaaga ctggaacagg gtagttacgg agtttctctt
     6481 tgatggctaa ctctacctca acgtcacgct tattgtaatc aatgaaagca gaccacttgt
     6541 cgggcgcgtg attggggaag tttcgtgttc gtccaccgtt aaccttggtt ggtttacaag
     6601 gaaggcagaa gtaacgaatt aaatctccgc cttcctttaa cttttggttt ttgagcttga
     6661 ggacagttcc gactccttca agtgagagtg gcagaccaag atatgctgac caaaccatac
     6721 tgcatcgcca tgagtttgga gataggaaac cttcggatag taattctggg tgatgtttct
     6781 tgagccagtt agacagacag atgcgttcaa agctggcatt aaatgcccac ttgatgatag
     6841 tgtcatctac caatgcttgt aggatttcat caggaagttc ttcctttgtt aagtcataaa
     6901 cggttactgg ttcgttatca actgagacag ctagaagaag aatttcaaag gaatcatctt
     6961 cagcgtagcg atagacacca gactttctca aatccacttc gcagtaggtc tctaagtcaa
     7021 tcgatagttc tataattggc atagtttgtc ctttcataaa aaggtggcag gagtgctgcc
     7081 accagaagta ttaacggcta cgatgtagcg gagttgagtt gttgtcttga cgtttctttt
     7141 cagcttttcg ctctttctca cgacgaatat cgtcacggat ggtcatgtag tttaggtaaa
     7201 gtccaagaaa aacataagtt ccaagaattg ctgaaagtaa aatgtagtag attgtcataa
     7261 gttaaatcct ccattattag ttcaagaaat catcatcgtc atcagtcgca aagtcatctt
     7321 ctgcacgagt acgtccaccg agcggttctc catcacgaag tttttgcagg ttgttaagcc
     7381 cacaagcaat acccttgtta ccgttagagt tgaaggcata gaaggagata gacgcacggc
     7441 catagatacc tgagtagagt tcagaagtat cgataatctc ttgacgatta ccgtccacaa
     7501 caccaggttt atgcggtgag ttggcattga cgaagtaggc attgcgataa gcgtcatcat
     7561 cagggcgttc taagtcccca tcacggagtg gtgttttaag gatagaaagt gctggtactg
     7621 ttttcccatt gcctttgagt tttgcctcac cttccttata ggcaagttca atagctgcct
     7681 tgattttatc gacagtctca atatcatctt ttggaatgat gagggagacg ctgtacttcg
     7741 gtgtgcttcc gttaatggac tttggttcat tggcattcaa gtagctgaat cgtgtgtttt
     7801 taccagtgat cacttttgtt gtttgtactt tagttgacat ttttttatac ctctttgaat
     7861 tcatttttag ctaggttcat ctcttgacga ctatcatcaa gaggaacgag tgttggttta
     7921 ccacttggtt tgataatcag accaccaagt aggtcattaa aggttttctt gccaaggagt
     7981 ttgctcatgg cagtgatggt caggagtttc ttttcgtaag ggtcaaagcc agcctccatc
     8041 acagcttgag tgacagcagc ttcgtctgaa aacttacgaa ccgaacgtcc ttctacaagt
     8101 ttgtagcccg gaatattgtg tcctttagtt gcttctttca aagcataggc tttgacatca
     8161 tttgcccacg aaaccagcaa gtccagttta ggcaaaatct ctgcaatatc ctcatagtct
     8221 agagtagcag ggtccgcaaa ttccatcttg gcgagtgcca agttatcctc tgcacgtttg
     8281 cgacagacat tcttgagttt gcagaactga cagtgtttac cagaggtcat ctccccttcc
     8341 cctttgaagg caagttcagc tttgggggag agttcgtttt cagcccactc aagcagttca
     8401 gatttgtcca tctcaaaggt ggagatgtta ttcttccgtg gttgaaagat ggtcatggtg
     8461 accttgtcaa aatcatagag gtcatcaaac atctcaagag cacctaaagc gtagcacatc
     8521 atttgtgggt tgtggtcggc atcaactaga actcctaatc cgtgtttgta gtcgatcact
     8581 tgaagcagtc catcagccac aatcagacag tcgcctgttc caaagccttc aggtacccat
     8641 atagagaaat ccagtcgttg ctcaaccaga actgttggat ctcgagaata gcctttagct
     8701 ttctcaactt gctccatgac gtagttgcga tattcctcgg cacaggtttg catttcttca
     8761 ttgtagaagg ataagtcctt agttggatca cgcaccttcc tacccaatgc cttctcaaca
     8821 agataagcgc atagctcgtg agcgtctgtt ccttcaaggg caaactctga ggtcacatct
     8881 ggcatatctt cggtaagtcg tacagaaggt gggcagttga gccagcgatg agaagcagaa
     8941 gcagagagta ctgcgtgatt agtcattgcc aattcctcca gcttcttcaa gaacagctgc
     9001 gtagtgctca ttggctaaag tagataatga ttcagctcca tatttattga gaagagcacg
     9061 aacctcattc ttgtagccat ctttagcttt ggtcgctagg accgcacgaa catcttctag
     9121 cttaagtacc ttttgtgtct ctggttttgg ttcttcagaa gttgtttcag tttcttcctc
     9181 gctagagagg agtttcttga actcatctac caagcgtagg tagtatttag ccgtgccttc
     9241 catctcggta atcagttcaa gcagttgttt atgttgactc attttgtttc ctccttttgt
     9301 aatttacgtg ctaagagtct agcaataacg ctgatggcaa tgagtgtgtc tgtcaagtct
     9361 tcttgttctt gacgattcat ggtgttttcc atagaaagtc ctccttaagg tttgtttggg
     9421 ttatctcgcc cttacaccta ctagggggac ttttttgcgt tttagtctaa acagattcaa
     9481 aaaaaatata aaaaattgag cgatgggatg tcgctcaata gttatatata gaagaaaaaa
     9541 tttttttgaa actttttgga ctaaatgctt tcattcttcc cctagtaggt aggaagggaa
     9601 accttcacag attatttttc caaaatggag gctatgattt atgcaattta ccttatctca
     9661 ttcaggacag actggtgttc aaacgacaac agtttatcct catcaagtaa cgattactga
     9721 taaagcaacc ttacaggcta ttgctcagta tgatcatgtg gcaggcttgt ttacaaacaa
     9781 tacccgctcc aatgccaact tcatcaaatc agatgtattg gtcatggata ttgataatga
     9841 ccatacggac aactctgatg aatgggtaac ggaagagcta cttaaagata tctttgcgga
     9901 ttacaacttt gctttagtga ccagtcgtaa ctatttggtt caaaaagggg ataaggctgc
     9961 cagacccaaa ttccatatct acttccaaat caatgaagtc acagataagg acacctatgc
    10021 cttactgaaa gaagaacttg taaatcgcta tggcatcttt gacactaatg ccaaagatgc
    10081 ggctcgcttc ttctttggaa atcctaacgc aaaagtccta tggcatgatt cttggttgac
    10141 cattgatgag gatttactgg atgacatggt tgctcaagat gatgaagagg actttgatgc
    10201 agacttctat cagccaccaa caggtccaat cactgaaggt agtcgcaact caaccatgtc
    10261 ggtttttgcg gcgaaaattc tcaagcgttt aggtgtaacg aaagaagcac gagacggttt
    10321 tgatgaacag gctctcaaat gtgttcctcc tcttgagaaa gcagagcttg acactatttg
    10381 gggcagtgct gttcgcttct ataacaaaac catcaaaaac tccaaagatt ataagtcacc
    10441 agaagagttt caaagggaat cactaaaacc tgatgactat tcagatgttg gtgaagctgg
    10501 ggttcttgct agagaatatg ccgataaact agcctacacc aatgcaacag actatctttt
    10561 ctacgatgga acacactggc gtgagaataa gcagctggca ttaggggcag tcgtaaattt
    10621 tacagatgat caacttgcgg aagcaaacac ttttttagaa gtaacagaga aacaacttca
    10681 atctacaggt attgatgaaa tgatcatcaa ggcaggaggg aaacgtctag aaaatgcggt
    10741 tgagacctct ctacagttga aatatcttaa agcctatctt gcggcaaaag agttccataa
    10801 atttgtcatg aaacaccgtg actataagaa tttaatggct gtctataata ctgcaaagtc
    10861 tatgcttacg gttgaattat cagagttgga tagtgatgac atgttgctca acactcctga
    10921 ggctacctat gatttgcgac aaggaacaaa aggacaacaa gaacataatc ctgaagacta
    10981 cattactaaa atgacagctg tctctcctag tgacaaaggc caggacttgt ggcaggaaac
    11041 cttggctacc tttttctgta acgaccaaga gttgattgac tatgttcaag aaatcattgg
    11101 gatggcagcg attggtaagg tttatcagga acacatgatt attgcctatg gtggcggtgc
    11161 aaacggtaag tctacctttt ggaacaccat tgctcgtgta ctaggaagct attctgggaa
    11221 attatcggcg gatgccttaa ccatgtctaa caagcgaaac gtcagtcctg aacttgcgga
    11281 gcttaaagga aagcgtctcg tgattgcttc tgagatggct gaaggaatgc gacttaatac
    11341 agccgttgtt aagcagatta cctctacaga tgaaatccaa gcagagaaaa agtacaagga
    11401 tcccttccac tttgtgccat cacatacgct ggttctttac accaaccatt tgcctaaagt
    11461 aggagcgaac gatgatggaa cttggcgacg tttggttgta atcccattta atgccaaaat
    11521 cactggtcgc tctgatatca aaaactttgc agaccatttg tatgacaatg cggctccatc
    11581 aattttgtct tggattatcg aaggtgcaga aaaagccatc aaggcaaact tcaagacaag
    11641 tgtgccatct gctgtttcaa attccgtcaa agcctacaga gaagccaatg attggttagg
    11701 gcacttcctt agtgactgtt gcgaagttgg tgatcagttt acagaaaaat ctggagaact
    11761 ctacagtcag taccgtgcct actgtaccaa aaatatggag tacacgcgca gcacgacaga
    11821 tttttactct gccctggatc agacaggatt tagacgcaaa cgtaccaata aaggaaacct
    11881 tattctaggt ttgaaattgg ttgatgatga ctatgatttc ctagactagt gaccatcatt
    11941 ttccatgtcc tacttccaca agggagatgg agagggattt tagatgtgct agtcattgac
    12001 ctgatgacaa gaatttatga gttctactca ctagaacaga ttagtcaaaa ggactagcac
    12061 gactaacatg atttgatttt gtgtaggtct attatggtct tttctaaaac tatcctataa
    12121 gtaaaactta ctataaaaaa gcctataagg agagttttag aaatgactgt actatacctc
    12181 cacacgtcaa tttgacgaaa ggatttgtta tgcgagaaaa agttgttgaa cagaagttag
    12241 taagtgaagt gaaaaagcgt ggtggaattt gtcctaagtg ggtgtcacct tcttttggcg
    12301 gtgtaccaga taggttggtg tttttaccca agggtaagtt tggcatggtg gaggtgaaag
    12361 ctcctggtgg aaagccacgt ttactacaag tgacaaggca cagactattt gagcgattag
    12421 gcttcaaagt tcatgtgctg gacagtattg agaagattgg agaagtgcta gatgaaattg
    12481 agtttacatg actatcaaga agtcaccaag gacttcatca taagaacccc ttatgcggcg
    12541 gtcatcttag acatggggat gggaaaaact gctacgacct tatcagctat caacgagctg
    12601 atgtttgatc gctacgaagt ctcaaaggta ctggttatcg cacctcttcg tgtcgcaaac
    12661 accgtatgga gtgatgaaat agatcagtgg gaggagctga gacacctccg ttatgctaag
    12721 attgttggaa caccaaaaca gagaagagct gcccttgagc aagatgcgga tatctacatc
    12781 gtcaaccgtg aaattctccc ttggttggtg gaacaatgta gtccctactt caagtgggac
    12841 atggtagtta ttgatgagct ctcgtctttc aagtcatggc agtccaaacg cttcaaggcc
    12901 tttatggcca tgcgccccta catgaagcgt gtcgtgggat tgactggcac accgagttca
    12961 aatgggctta tggatttgtt tgcggagttt aaggtcattg atggaggaga acgtttaggt
    13021 cggttcattg gagaatatcg tagcagatac tttgaggaag gtcgcaggaa tggcaatatc
    13081 gtctatgagt atatccctat ggactatgcg gagtgccaaa tctatgacaa gattgacgac
    13141 atcactattt ccatgaaagc catggattat ctggctatgc ctgaattgat atcgaccaag
    13201 aagctggttt atcttactga caaagaaaaa tctgattaca agcagttcaa gaaagattac
    13261 gtgttatctg accttgaaga tggtgaggta acagctgcca atgcggctag tctgtcaaac
    13321 aagctggtgc agatggccaa tggtgccgtc tactcagatg actatcaagt ggtgagccta
    13381 catgaccaga agctcgatgt tctggaagat attatcgaag cagcaaacgg tgagccagtt
    13441 ctagtggctt attggttcaa gcatgacctt cagcgtattg agggacgttt ggcaaagctc
    13501 aaggttaagg gaacggtact taaaactgag caggacatcc gtgagtggaa taagggaaat
    13561 attacagttg gtctccttca tccagcaagt gctgggcatg gacttaactt acaaaagggt
    13621 ggccatcatt tggtttggtt cggtctcact tggtctttgg agctctacca acaaactaac
    13681 gcccgactat ggcgacaagg gcaacaagct gagactgtgg taatccaaca cattgtaacg
    13741 gaaggcacta ttgacgagga aatcctcaaa gcactggaaa acaaggatgc ccaacaatca
    13801 cggctgattg aagctgtcaa agcacaagta ggaggaacgg atggataaag cggaatatat
    13861 cctaacgcat tataatgaac tcaaggggga cttggaaatg ttgcagtatc gcttggagaa
    13921 ttttaagcct gtgactgaga atgaagtgat tgggtcactt gtcttcgaac ggtcggatga
    13981 acctaaagtc acctctactc cggcaaatct acgttcagag gtgatagccc taagttttcg
    14041 tgacaagatg attcaggaaa atgaagagct cttagcagat ttgactcaac gatatatacg
    14101 actggcaaat gaccttgata attttgagat ggctattcga tttcttaagg atgacctagc
    14161 tgagtttgca caagaaatgt taaagccaga gtgtaattgg gatagtttga tgagggagtt
    14221 tcacattagt cgtagtacgg ttagaaattg gcgtcgtaag gtattggatc acgttagggg
    14281 agtttatctg aagatgggct attccttaga aaaataacct ccccttgcac tccccctgac
    14341 ctaacagtaa cctccctctg tactaaatgt gacctaacat tgacctccct ttgtaaaaat
    14401 ttgtggtaga attgtaagtg tcaaaaaaga taaaaatctc ccagtaatga ctggatatac
    14461 cttcgcttgt acggtaatat aacgctacaa aaacaagagg aggtcgtcaa aatgacaaaa
    14521 cgccaacaag aaaaactcaa cgccctttta acagcgattg ctcaagaaga acttttggtt
    14581 gaaaccttgg aaacacgaaa aagtgataac ctagatttct acgatgtttc ggtttgggga
    14641 gttaaaagag cactcgagag atcctacgaa gcaggccaac aatcagtaaa ataaatcaaa
    14701 gcctagccct caagggttgg gctttttgcg tggaggaaaa catgattttt accagtgaac
    14761 aagtttcaag tggacacccc gacaagctct gtgaccaaat ctcagatgct attgtgacgg
    14821 aatgtctcaa gcatgataag aatagtcgtg tggcggttga aaccttaatc aaagataacc
    14881 aagttgttgt ggcaggagaa gtctccacca agcacttctt caacctcgaa ggcattgtca
    14941 aaaaggttct tgagccttat ggcatggatg atgtcatggt gacgaacgtt cttggagttc
    15001 aaagtccaga catcgctcaa ggtgtggata agggtggtgc aggtgaccaa ggcattatgt
    15061 ttggttatgc gaccgatgaa acccctgagt tcttaccact tccttatgtg ttggcgactc
    15121 gtgttcttga aaagttaacc aaccttggtc accctgcctt gggtaaagat gccaaggctc
    15181 aagtcactta tgactacgaa aacaaacgta tagagacctt ccttgtctct atccaacatg
    15241 atgaggaggt tgaccttgca ttcgtgaaac gcattgttac tcaaaccatg atgtcggttg
    15301 ctcaacgcta ccgtcagaac cttgacttta gggttttggt taacccaaca ggacgctttg
    15361 ttctcggtgg ctcttacgca gatgctggtg tgactggtcg taagattgtg gcagatacct
    15421 acggtggttt tgcccaccac ggtggtggag ctttttctgg taaggatccc tctaaggttg
    15481 accgttcagc cacctacatg gcacgaaaga ttgccaagga ctttgtccgt gaaggttatg
    15541 ccaaacgctg tgaagtccag ttagcttatg ccattggggt tacggagcct gtaggtgttt
    15601 atgtgaacac ctttgggaca agtgattata ctcttgaaca actagtagga gtggttcgtg
    15661 aacgctatga tcttacccca caaggaatta tcaaggatct gaacctcttg gacgtggact
    15721 acaccaagac cacttgcctc gggcatttca ctaagcctta ccttccttgg gagcagtaag
    15781 atgccacgtc gaccaagcac cgcttgcaag cagcatggct gtcccaacct tgtgacctat
    15841 ggaaacaagt actgcgatga ccacaaagct aaccataccc ttgatgccaa gtcaaccaaa
    15901 gccaaaggtt acaactctcg ctggaacaag gcacggcttc gttacttaaa gctccatcct
    15961 ctttgtgttt actgtcaaag gaaaggacga ctaaccaagg caacggtggt tgaccacgtc
    16021 actccccacc gaggagacca agacctcttt tggaaccaat ccaactggca agctctctgt
    16081 aaatcctgtc atgaccgaaa gactaagacg actgaccgat atgtggaata tacttatcgg
    16141 ttctaaattt agagtttcgt tacaaaagta tccctttttc catcatttgg ggtagggggg
    16201 tataaatctc taaacccttg tcccacaaag accgacgccc cctcaaacgt gtaatttcgc
    16261 aaaattcgtt aagggggact taaaatgtgg ttaaaggtta gttgaaacct attcagatta
    16321 acattccttg ggagaggtag tttcgttttt ttgttttgat ttttttggga ttttgatgtt
    16381 gaaatgtcca aaattgacta aaatttagtg tttttagatg tgggggtgaa ctcttgaacg
    16441 aaaaccagcg cagacagatt tgggtgatga ggagtaaagg tttgggatac ggtacaattg
    16501 ctcaggcggt taatcttcca agggatgctg tcagaaaatt ttgtagtcgt agaccagagc
    16561 taaaaggcta tggccatgtc gtccaacaaa tgattgaagc gcaaggctat gattactgtt
    16621 tgacctgtgg tatcaaacta gaccataaac tggtaggcag accaaaaaag ttctgctcag
    16681 ataaatgtcg taaggtctat tgggatacac atagagagga acatgacaaa gataaaactg
    16741 catatgatga actgacttgc caaaattgtg gcaggtcttt ttttcatatg ccaatccaaa
    16801 tagaaaattt tgtagccata gctgttacat ccaatcacga ttttacaaag gaggtcataa
    16861 tgaccaatca accaactatg gagattaagg aacttctact aacggaattg caaccagcct
    16921 cttataaccc tcgaaagcaa ctgaagaagg gagataaaga gtatgaaaaa attaaacaga
    16981 gtttactgaa gtttggctat gttgacccta tcattgtcaa taaagaccta acggtcattg
    17041 gtggtcacca acgcttgacg gttctaaaag acttaaagta cgaaacggct aagtgtgtca
    17101 ttgtctctct gtccaaggaa gatgaaaagg cactgaatat tgccctcaat aaaatcactg
    17161 gtcaatggga tgaccaactc ctggcagatt tgcttttaga tttgcaagag tctgatttca
    17221 accttgactt gactgggttt gaaccgccag agattgatga tattctttct aacattcatg
    17281 ataaagactt gtctgaagac gactttgatg tggaagaaga gctgaagaaa ccaacggtcg
    17341 caagacaggg tgacatttgg caacttggta agcaccgagt gatttgtggt gattcaacca
    17401 aggcagaaac ctatgaccag ttgctaggga ataagaaagc caacctcgtt gtgacggacc
    17461 cgccttacaa tgtggatgtt gaagagacag ctggaaaaat cctcaatgac aatatgtctg
    17521 atggagactt ctaccaattt ctctataata tgttcagtca agtagaaagt catatggagg
    17581 cagatgcctc tatctatgtc tttcatgccg atacagaagg tctgaatttc cgtaaggcct
    17641 tcaaggatgc aggattctat ttaagtggct gttgcatctg gaagaagaac tcacttgttc
    17701 tcggacgcag tccctatcaa tggcagcacg agccctgcct ctttggttgg aaacaaaaag
    17761 gcaaacacca atggttcagc gataggaaac aaaccaccat ctgggaatat gatcgaccta
    17821 aatctagcaa agaccatcct actatgaaac ccgttcagct tatggcttat cctattcaga
    17881 attcttcaat gcgaggaacg ttggtattgg acccatttct tggttcgggt tcgactctta
    17941 tggccgcaga acaaacagga cgtatctgtt atgggattga gcttgatgaa aaatttgtgg
    18001 atgttattgt caaacgctac atggaagcaa ctggcaatac gactgtgaca gtagtccgtg
    18061 atggtcaaac gttgacctat gatgaagcag tatcagctat ggaggaaggc ctatgactct
    18121 aacatttatt gatttctttg caggggttgg tgactccgtt gacctttcat atccagactc
    18181 tcaaacaaga cgagccagag taggcaaagg tatcgcccac aacctttcct gtggcggaca
    18241 gatgggtgcg gtggtttgga atggtcgagc ggttaaaatc agacggctca cccctcgata
    18301 gtgtttcagg atccaaggct tttcagatga cctgtttgac aaagctgagg ctgtcaattc
    18361 cggtgctcag ctttataagc aggctggcaa tggcgtgact gtcaccgtgg tttatgcaat
    18421 tgggaaagcc attttagaag ccaaaaaatc tgcaaatcat aagcagaaat gactggatat
    18481 aggtctcctt tagagttaat atgtaatcaa caaaagaaga ggagaacaaa tccatgaaaa
    18541 caacaacact tgaaagactt tacagctatc accaagcaac tgcaagcatc attccctaca
    18601 aggattgggt gattgttgct tactctggtt ataaaggagt tagcgtagat atttacgaat
    18661 caacagatag ccttgaggac ttcagtaatt ttgaaagacg atttgaccgc atttaccaag
    18721 aagaaggaaa tttccaagac caaggtcacg cagtgaaatg ggcatttgaa acaataggag
    18781 tataaaatga acgataagat tctaaaccga attaagttca cctatcccaa aggcacaagg
    18841 gtgaggttaa tccagatgga cgaccctcgc ccagttccag ttgggacgct gggcacggtt
    18901 cttgatgtgg atgaccttgg ctcactcatt gtctcttggg acaatgggca gagcttgaat
    18961 gtattgtacg gaattgatag tgttgaaaaa atctaaaagg tttctcttga agcctttttc
    19021 ttgttcttaa aaggaggtga gaccgtggca gttagagggc gaaaaccaaa gcctaccaat
    19081 ttgaaaatac ttgaaggtaa tcctgggaag cgacctctgc ctaccaacga ggttaagccc
    19141 agacagaaag ccccacgttg cccacagtgg ctggaagacg atgccaagaa ggaatggaaa
    19201 cgaatgggca aaattctcga acaaatgggg atattaactg aaatggacat gacggccttt
    19261 gcagggtatt gtcaagccta tgcaaggtgg aaagaagcgg aagagtttct ctccaaacat
    19321 ggatccatca tcaagacccc aaatggctat ctccaacaag tgccacaggt atctattagc
    19381 cagactaatt tgaaaatcat gcttaagttc tgtgaacagt ttgggcttac cccatcagct
    19441 agaaaccgat tagctacaat ggatagcgag gttggaactg gtgatgaaat ggaagattta
    19501 ttaggaggta ttttatgact tatcactatg aaccaagtcc ttttatgctt ccgacgtcac
    19561 gttatgacaa ggcaaaggct gatagagcag ttacttttat caataatctt gcccacacca
    19621 aaggaaagtg ggcaggtaaa aagtttgatt tattgccgtg gcaggaacag attgttagag
    19681 acctgtttgg aattgtaaag gaagatggta accgtcagtt cttaaccgcc tatattgaaa
    19741 ttcctaaaaa gaatggcaag tctgaactcg ccgcagccat tgccctttac ttgctctatg
    19801 cggataatga agctagtgcg gaagtgtatg gagcggcttg tgaccgcaac caagcctcaa
    19861 tcgtatttga tgtcgccaag caaatggttc aaatgagtcg accgcttgag aaacgctcaa
    19921 agattatggg ggcaaccaag cggatagtca actattctaa tgctggtttc taccaagtcc
    19981 tctccgctga gacaggaacc aaacacggtc ttaacgtttc tggactagtc tttgacgaaa
    20041 tccatgctca acccaatcgc catctctatg atgtcttaac caagggttct ggtgacgcga
    20101 gggaacaacc tctctttttc attatcacaa cagctgggac agataaaaac tccatttgtt
    20161 atgcacttca taccaaagca cttgacattc ttaaaggtcg caagaaagat acctcctttt
    20221 atcctgttgt ctatggtctt tctgatgagg atgattggaa tgatgaagcc aactggctaa
    20281 aggctaatcc atcacttggt cataccattg gtcttgaccg tgttcgtgaa gcctaccaac
    20341 aggctttaga taacccagcg gaggagaatg tctttaagca attgcgtctc aacatgtgga
    20401 cgagttcatc tgtggcatgg atacctgaac atgtttatgc gaaaggtgat gcgccaattg
    20461 attacaattc tctaaaagga cgtgactgtt atgcagggct agatttatcc agtacatctg
    20521 atattaccgc ctttgtcctt gtttttccgc ctcgttatga ggaagaaaac tacatcatct
    20581 tgcctttctt ttggttacca gaagatacgc tttcgttacg aattcgacgt gatcatgtac
    20641 tgtatgatgt ttgggaacga caaggttata tccacacgac tgaagggaat gtggttcatt
    20701 atggctatat cgaaaaggtc atagaagact tatcaaagac ctatcacatt aaggagattg
    20761 cctatgaccg ctggaatgca acacagatgg ttcagaacct tgaaggaatt ggattgacca
    20821 tggtgccttt tggacagggt tataaggata tgagtccgcc atccaaagaa ctctacaagc
    20881 ttatgataga ggggaaagtt caacacggtg gtcatcctgt acttaaatgg atggggcaaa
    20941 atgtggtgat gcgacaagat cctgctggta atatcaagcc agacaaggaa aagtctgttg
    21001 agaagattga tggtattgtc gcccttatta tgggattaga ccgttgtatt cgtcatcaag
    21061 gaaatgaagg cagtgtctat gatgaacgag ggatattgag tttttaggaa aaataaagtt
    21121 aaattctttc aaaaatagct caaaaatgac tggataaacg tcctctttag agttaatatg
    21181 gtcacaacaa aagaagagga gaacaaaaac atggcaacta atgcacgcat tggactttta
    21241 acaaaatcaa acactgcaac atttattaag gccgcttatg aagggtatcc aagttacaca
    21301 ggaagcctac taacatcagc atttaatagc ctcaaacaag ttaaagaact tctaaaaaaa
    21361 ggcaacatca tcatgttgga agaaaacctt gatgaggtag aaacagatag ccttgttaaa
    21421 gtgacagaga acattcgctt tgtaggaagt gagagtgacc ttgaaggcga ttatttagca
    21481 gactacactt acgtatacaa agaaacagaa aaaagatggt acattctaac ggatggtaaa
    21541 ctcgtaccat gttatttgta aactatcact atgcacttcc gactgaggtg ctttttgttt
    21601 actcaaaaag gaggtcaaat gggtatttta gattggattg gatcgaagcg ttcaagagat
    21661 aagccacata atagttatga gggacaagat ttttcatacc tctttggacg gacgactagt
    21721 ggtgaaaccg tagatgagtt taaggctatg cagacgacgg ccgtttatgc ttgtgtgcgt
    21781 atccttgctg aagcagtagc gtcacttcct attcacgtct atgaacggac agaaactggg
    21841 aaggagaaaa agctggacca cccactgtac tttcttcttc atgatgagcc aaatccagaa
    21901 atgtcatcct ttatttttcg agaaaccatg atgagtcatt tgttaatatg gggaaatgct
    21961 tatgtgcaga ttatcagaga taagggtgga cgagtgatta gtctctatcc actcttgcct
    22021 gataagatgt ctgtccatcg tgatgatagt gggagacttt actacaaata ccagcggcag
    22081 acagaagaaa atcctaattt caatgataag ggtactgtct tattgaagca ggaagatatt
    22141 cttcatgtgc ctggtcttgg gtttgatggc ttgattggtt actcaccaat tgcgatggct
    22201 aaaaatgcga ttgggatgac cctagctacc gaaaactatg gggcatcttt ctttaaaaat
    22261 ggcgctaatc caggtggtgt tttggagcac ccaggtatcc ttaaagaccc taaacgagtg
    22321 agagattctt ggaatgccgt ttacaatggg gtcacaaatg cgcataaagt ggctgtactc
    22381 gaagaaggaa tgaagtatac tcaagttgga attccccctg aagaagccca atttttacag
    22441 acacggaagt ttcagattaa cgaaattgca cgactttacc gtatcccacc acacatggtt
    22501 ggtgatttgg agaagtcgtc tttttcaaat atcgaacaac agtcacttga atttgtcaaa
    22561 tataccttag acccttgggt agttcgttta gaacaagcct tcaagaggtc tcttttttta
    22621 cccgaagaga agaaacaata ctttgtcaaa ttcaatgtgg atagtctact tcgtggggat
    22681 taccaaagtc gaatgaatgg ctatgccatc gcaagacaga acggttggct gtcaactaat
    22741 gacatccgtg aattggaaga tttgaacttg ttgtcagatg aagaaggtgg caacctctac
    22801 ttgattaacg gcaatatgac caaactagaa gatgctggtg gtttcatgaa gcaacctacg
    22861 gaaactgagc caactgaaca tgcaatagag gaggaagaaa atgcgtaaat tttggaattt
    22921 tacagacgaa ggtggcgccc gtacccttag gattgaaggt cagattgcgg acgagacttg
    22981 gtttggggat gaagttaccc cacagctctt taagaatgac ttgttagcag gaaaaggcga
    23041 tatcaccctc tggataaaca gtccaggggg tgatgtgttt gcggccgctc aaatctataa
    23101 catgcttatg gattatcaag gcgatgtcaa tgtcatcatt gatggtttag ccgcaagtgc
    23161 tgccagtgtc atagccatgg ctgggacaac tgtttctatg agcccagttg ctatgatgat
    23221 gattcataac ccttggacca tggctcaagg tgaagccaag gatatggcta aggtcattga
    23281 gatgcttggt gaaatcaagg agtctatcat caacgcttat gagctaagaa ccaatttgtc
    23341 acgaaccaag atttctcatc ttatggattc ggagtcttgg tttaatgcca agaaagctgt
    23401 tgagcttggt tttgcggata aggttctctt tgagaaagag gaggcatcaa agcagggctc
    23461 tcaaaatagt tacaccttca gtagagtaac tgctgtccat gatttggtgg tgaaactgca
    23521 agcgagcgtt caaccatcaa aaccagagaa aaccatcccc ttcaatcaat tggaaaaacg
    23581 attgaactta ttgaaataaa aggagaatac ttatgtctaa actacttgaa ttaaaagaaa
    23641 aacgtaacaa ggcttggcag gatgctaaag cttttttaga tgcctgtgaa acagctgatg
    23701 gcatggtgtc tgaagctgat gcgaaacgtt atgatgacat ggagacaaag gtcactaatc
    23761 tgaataaaca aatcgaacgc ctagaacgcc aagaaaagtt agacttggag ttgtcacaac
    23821 ccacatcaca ggctttgact actcagccaa cggttattgt agacaaagaa aatgaagatg
    23881 acaagaaagg tatcgcttca gatgtctaca gtcaaacttt ttggaccaat gttcgaaaac
    23941 gtcacttttt tgatgtgaaa gatgttcttc gtgtcggtga agataccgaa ggtggacatc
    24001 ttgttccaga tgagtatgag aagaaattgg tacaagggct tcaggaagaa aactttttcc
    24061 gtgggcttgc gaccgttatt aaaacgtcta gtggagaacg taagattcca gttgttactg
    24121 gtcatggttc agcctcttgg atggatgaga acggacttta tccagaaacg gatgaaacct
    24181 ttgggcaagt gactcttgat tcgcataaga ttgggactgc cattcgtatt tctgaagaat
    24241 tgctcaatga ctctgtcttt gaccttgagt cgtatatgat tgcggagttt gcccgccgca
    24301 ttggaacgga ggaggagaag tccttcttga ttggtgacgg ttctaaaaaa ccaacaggga
    24361 tttttacgca agcagaagtt actggaccta cgacagcaac caaagacatt acctttgatg
    24421 atatgattga gctgtatcac tctcttccag ctccttatcg taagaatgcg gtttggattt
    24481 tgcatgatac gacagtaaag gcaatccgta aattgaagga taataatggg aattatattt
    24541 ggcaaccgtc aactcaagcc ggtcaacctg atttgattct caaccgtcct tactatacgt
    24601 caacctttgc gccacttcca gaagcaggaa acaaagcgat tgcctttggg gatttctctt
    24661 actactggat tgcggatcga caaggtcgta ccttcaagcg tctcaacgag ctttacgcaa
    24721 ataatggaca gattggtttt ttagcgagtc aacgtgtgga tggaaaatta gttcttcctg
    24781 aagcggttaa ggtattgact gttaaaggta aaggctaatg ataacactgg aagaagcaaa
    24841 actgtattta aagattgata acgatgatga agatgaactt atattagctc tcattcgtag
    24901 cagcaaatct ctctgctttg acattcaacg gcatgaggaa tcctcagaac tcttaaagac
    24961 ggcaatccta tatggggttg cttttcttta tgagcaccga gaattagcga atcataagga
    25021 attaaaagag acactttatc atttgcttct agcagatagg aaggatgtgt tctgatgaag
    25081 atagctcctt taagagaaca gctagtcttt caagaaaagc aaatcaaaca agatgagatt
    25141 ggcaacgagt cagctatttg ggacgacctc tttgttcgct ggtgttcttg tcgccctctg
    25201 gctttaacag aaagtgatgg gagtgctatc aaactgattc atcacaagat acagtttacc
    25261 ttgcgttatg acaagaaggt tcttgccctt aattctttaa cgacaaggat ttccttccgt
    25321 gaccagtttt acgctatcga gtccattgat ggtgataccg ttccacggca gttgatttat
    25381 atagttgcga ttaaggagga agatcatgac taggattggg cttgatgatt tagtttctgt
    25441 tgttgaaaac gagctgacta cttatgctaa ggaaaccacg gataccatgc gtgaggtagt
    25501 tgaagaagta acggatgaag ccgttgaaac cctaaaagta acctcgccta aacgtcgtgg
    25561 aaaatatgct agaggttgga agagtaagac aactactgat actaatacag cactgactaa
    25621 aaccattcac aacggaacac caggcctgac gcatctgctt gaagatgggc atgccaaaca
    25681 aaacggaggt cgtgtcaaag gacgtaagca catcgctccg gttgagaaaa aggcgattgc
    25741 gtcttttgaa gacaaattgc gacagaaact gtgaggtaga gtatgcaatt taaagatctc
    25801 ttttcagtct taaaggaaac caaactctca gtagcctatc accattttga ggaagggcac
    25861 agccccagtc cgccctttat ggtttatctg gttacggatt cagataattt tggggccgat
    25921 aactggaatt atcacaaaag gctcaacgtc cagattgagc tttacacgac aaagaaagat
    25981 ttagcaacag aaaaaacggt ggaatcagtt cttgatgccc accgtcttta ttttgacaag
    26041 gtagagactt acatcactag tgagaaactc taccaaacca tttattccat cacactatta
    26101 ggaggataac catgacagaa aaaaacaagg tcacctttgg tctacaagat gtccactggg
    26161 cagaagtcac cagtgaggga gctgacggtg ctttgactta tggcaatgtt gagcgtcttc
    26221 gtggtgctgc agaactaacc cttgaaccta ctggggacaa ggggtcttac aaggcagata
    26281 acattaactt ttacacctca gaatctaatg acggctatga gggaacactg aaagttgccc
    26341 tcttatccca ggagtttctg actcgtgttc taggtgagaa attggatgcg acaactaaca
    26401 ccatttcaga gattgcaaat agcgagaaaa aaaactttgc actgatgttt cgatttgaag
    26461 gggacaagaa agagaccctt catgttcttt attactgtta tgcatcacgg ccaactgttg
    26521 ggtctaaaac caagtctggg tctgacatca atgaggtgga gttgaccttt acggcaagtc
    26581 cacgtccact tgataagatt gtgcgacgca gaacgactga agaaaccagt gatgagattc
    26641 gtgagaactg gtttaagtct gtctttgaac caaccactta aaggaggaga acatgcgaca
    26701 aaatatcacg attgcgggaa aaacctatcc tttggctact aacgcctata caccgattgc
    26761 ttataaggaa caattcggaa aagactattt ccaagatcta tttaatatgt tgagcgctga
    26821 atctatcatg gctcagcttg aacaattgga agaaggggag gagttaaagg ctagtcagat
    26881 tgacttatct attttgtcag attttgacat gacctttttc caccgtctgt tttgggtttt
    26941 tgccaagtca gccaatcctc ggattaaacc cttcgaggat ttctttatgt cgatggaaga
    27001 attccctcta caagaagttg gaccagtttt aatgtctatg cttaaccaag ggatgactac
    27061 gagaaaaaag cagatgactc acaaacagcg agtgaggaag tcttcacggt agaaagctac
    27121 ctttcttgtt gtaaggagac gggtctttct attgacgact tgaaacacat ctcgattggc
    27181 atggctctgg attatcagac cgattatgtg gagctacgca ctaaagacca gaatggggaa
    27241 cgtagagcaa ctcaagcaga ctttgataat ttctagtagg agggaggggt gacaatggca
    27301 ggaagcatca aagggatcac cattgaaatc ggtggcgata cccagccctt acaaaatgcc
    27361 ttaaagggtg tgaacaaaca ggcttctgaa gccaccaagg aactgcgtca gattgacaag
    27421 gctcttaagt ttgatactgg caatgtgact cttttgactc aaaagcagga agtcttagcc
    27481 aaacaagttg aaacaactaa agaaaaactc gccacacttc gtcaagctca agcccaagtc
    27541 gaggctcagt tcaaggccgg taacatcggt gcagaccagt accgtgcctt tcagcgtgag
    27601 gtagagagca ctcaaacagt cttaaagggg tacgaatcaa aactagaaag tgttaacaaa
    27661 gcactctctg ataatggtac acaggtcgaa tcaaatcgtt caaaacttaa cagtcttcaa
    27721 aacgagcagg cacagttggt gtcagaaagt gagaaactca atagttcctt taagctacaa
    27781 gaatcggctt taggttcgac tgcaagtgag gctgataagt tagcacttgc cgaacaaaag
    27841 gtcgcttcac attcagaaat ccttgagaaa cagattcata atctggaaca acagctctct
    27901 ctgacaaaga gcgaatatgg tgagaattcc attgaggcta ataagcttga gaaaaaactt
    27961 aatgaaacaa agacagctta caacaatctc caaaatgaga tggaggagtt ggcctctagt
    28021 tctgcgagtt ccaaggcttc tttggaagag acaaacagtc tcttaaaggc tgaccttctc
    28081 atggagtttg gcgaccaact gggagagttg tcacagaaat tgattgactt cggtcaacaa
    28141 tcgcttgatg catttcttga agttgatgag ggtatggata tcattgtcac gaaaactggg
    28201 gcaactggtt ctgcccttga agagatgaca gacatcgcta aaaccctagc cactgaactc
    28261 ccaacggatt ttaatacggc aggaagtgcc gtaggggagt tgaatacgca atttgggtta
    28321 acaggagatg cccttaaatc agcctctacc cagttgattc agttctcaga gatcaatggg
    28381 agtgatgtga cgagctctgc tatttcagcc aagcaagcga ttgaggccta tggacttgaa
    28441 gcgactgatt tatcaagtgt tttagacacg gttacttata ccagccaagc gacaggtgtt
    28501 ggtgtccaag agttgatgga caaggcagta gcgggagcac cacaaatcaa agcccttggc
    28561 ctttcctttg atgagggcgt caccttgatg ggacagtttg aaaaagcagg ggttgattct
    28621 tctgcagcac tttcttcgct ctcaaaggca gctgttaagt atgcgggcga tgggcttacg
    28681 cttcaagaag gacttgctgg aaccattgag caaatcaaag cctcaaccag tgaaacaatg
    28741 gctctttctc ttgcctcaga aatcttcgga agtaaagcag ctccacgtat ggttgatgcc
    28801 atcaagcgtg gtgctttatc ttttgaagat ttagcaggaa cagctgataa ggcagctggg
    28861 attgtaacgc aaacttatga ggggacgctt gatcctattg ataagtttac aaccgctcaa
    28921 aacacggcga agttagcgat ggcggagatg ggtgatgcta ttgcagcaac cctagcacct
    28981 atcttagagg ttctcgccag tttacttcaa gctgttgcca catggttctc tggtctttca
    29041 gaacctgtga agcagtttat tgtcattgtc ggaagtttgg tcgcagccct tggtttagtc
    29101 ttaccgattt tcattgccct gcaagcagct gctatggcta tgggaacaac catcatgggg
    29161 atgataactg cagcagctcc aattgtaggg attattcttg gtgttattgc cgctattgcc
    29221 ttactagttg ttgggattca gcaactctgg caacatcacg aagggtttcg gacagctgtg
    29281 acagaaatct ggaacgccat ctttgccttt ttatctgtca ttatccaaca gatatcaagc
    29341 tttgtcatgt cgatatgggg aaccttgact acttggtgga cagagaacca acagctaatt
    29401 cttaattccg caaacactgt gtggacagct atttcaacag tcattcaaac catcatgacc
    29461 attcttggac cttaccttca agccagttgg gagaatatca aactgattat cacgacagct
    29521 tgggacatca tcaaagtggt cgttgaaaca gccataaatg ttgtcttagg tattatcaag
    29581 gcagttatgc agattatcac gggtaattgg tcaggtgcct gggaaaccat caagcaggtc
    29641 gtctctacag tttgggaagc catcaagtca ctgatttcga ttgttctaaa tgccattgct
    29701 cagttcattt ccaattcctg gaatggcatc aaaggcacta tgacaaactt actcaatagt
    29761 atcaaatctg tcgttagtaa tgtctggaat ggcatcaagt caacgattag ctcgattcta
    29821 tcgagcataa gttcaacggt atcttctatc tggaatggga tgaaagcaac catctcaggt
    29881 gtcctaagtg gtatttcaag cacagtgtcc tctgtttgga atggggtcaa atcgaccatt
    29941 acaaatgcca tcaatggggc aaaaaatgcg gtttcttcag caatcaatgc cattaagaac
    30001 ctctttaact ttaagattaa gtggccgcat attcctctgc cacactttag tgtgtctggt
    30061 tctgcgaatc cccttgattg gttaaaaggt ggtctgccta agatttccat tcagtggtac
    30121 gccaagggtg ggattctcac caaaccaacg gttttcggca tgacaggcaa tagcttgatg
    30181 gttggaggag aagcaggacg agaggcagtc ttacctctta ataaccaaac ccttggcagt
    30241 atcggtcgca gcatcgcagc caccatgcct aacaagggaa caagcataac agtcaatatc
    30301 acggatgttg tgattcgtga agaagcggat atgaaaaaac tagccgatta tgtggctggt
    30361 cgactagctg atgaaatgac tcgacaagcc ttactgagag gaggaacggt gtgattaaac
    30421 ataatgaatt ggtactgaat ggaaaaggca cctcgtcttt tccttttaaa gttcttgtgg
    30481 aagatagacc gagtattcaa gtgccacggt ctaaaacgca actcttagac catcgtgggt
    30541 tgagtggggt gattgttcaa accaataaac accgtgatgt gattgaaaag tcttaccgct
    30601 tgtacctgat tggtgcgagt gagaaagagg tcaatgagtt tgcagctttt ctgatgcagg
    30661 aagggttttg gctagaaagt gaacgcctta aactcaccag gctctggtgt taccgaacgg
    30721 atagctttga catcaagcag gacgagcacg atgtgtttgt gattgacgtg acttttatct
    30781 gtcaccccac tcgctttttt aatagtgtgg ataggcaagt tttgagtacc aatggtgtgt
    30841 taaaaacaca aggctctgcc cttgcctttc ctaccattac catcaccggt caatcggtgt
    30901 cagaaacctc attcacggta ggtgaccagg tgatccgcat tgagaaattt acagagcctc
    30961 ttgttatggt taatcagcct gatcgtccta gttttaagac cctatcaggg aaagctgtca
    31021 agtggtctgg ggattttatc acgattgatg ccagtcatcc aactcattct gttggagttg
    31081 ttttgggaag tgggatctta tcgcttactt ttgaaacgaa ttgggggtgg gtgtgatgct
    31141 ttaccttctt ggcggtcaaa caaagacacc gaaatggaat ggtcagccat tatttgaaac
    31201 ggtgagtgca acggtagaag aggagctgaa tagcaccttt cagctccatt taacttatcc
    31261 gattacggat tcaggtattc atgaaaccct tagagcagat gagttgattt tgtgtccaac
    31321 tcctgatttg ggaaagcagc tctttcgtgt taagcaggta aagattcaag acgatacgat
    31381 agagcttgag tgctatcaca tttcagatga tatgatgaag cgtcagatta agcctttttc
    31441 agcgactaat actacctgcc aatctgctct tatgaggctg gttgaggctt gtccatctga
    31501 tttaggactt tttagctttg acagtgatgt gacggagcgt catacctatg tgtctgacga
    31561 agacttgaca ctttatcaag ctctaatgga tggtaaacat tccatccttg gaacctggga
    31621 aggtgagctc gttcgtgata actttcagct gatagttaag cagcaccgtg gcaaggataa
    31681 gggagttatt ctcacaagcc atcacaatct gaaagctttt ggggataagg gtgattctga
    31741 gaaggtcatt acgcgcatct atgcgacctc aacctttcag gcagaaggta gtgatgagga
    31801 tactgttctt tctgtcgttg tggaaagtcc cctcattaac caataccctt atgtccacga
    31861 agcacggtat gataataaca cgcttcagac agaggaagaa ttgcgccaat gggcgatggc
    31921 taagttcacg catgagcaca tcgatcacat ctctagacag ttaaccgttg aagcttatca
    31981 gcttgatggt caggaagtcc atctgggaga tacggttacc ctaaagagtc agaaacacaa
    32041 ggtagatgtt aagaaaaagg cagttagtta tacctttgac gctctagaag aagtgtacct
    32101 ttcagtgacc tttgatgatg aggttagctt tacgagatct ggatcatcag gaaacaattc
    32161 gctaaccagt gcggctaaga ccattcttga tgttaatcag tcggctacag aacaccgtgc
    32221 gtctaaggag cgagctaatt ttaacaaggt ctttgatagg cactttgagc gtcttcaaac
    32281 agaagttgaa gatggtatcg ctaaggccaa agcagaaggt gagcgttctg ggaagaaagc
    32341 tgcccttgat tatctggcaa cggatgccct tgaagcacga gtcgcagcac ttcaaaaagc
    32401 tacgattgat gagttgaccg tctctagttc agcatggatg acaaggcttg tctctcaaca
    32461 gattctatca gagtatgtga agagcctaga aattgaagca gacaaggtcg ttattcctgg
    32521 ccagcacacc ccagtcttta gtttggatag ggatgggagt ctttccattg atacgccact
    32581 cctaaaggtg agaggggaaa gcctagcgac aaaagttgat cttaaaacta tctctttaac
    32641 ccctggacca aagggggacg ccggagcaga tggggtgggt attcaattaa gggagcagta
    32701 ctacttagtc tctgcacaaa agactggtat taccacaaca agctctggtt ggagcaaaac
    32761 tattccctca ctcacctcaa cgcttaagta tctgtggaac tatgaaaaaa ctacgtttac
    32821 taatggctca acaacggtaa caacgccaat tgtcatcgga gtttatgggg acaagggtat
    32881 ggatggaaag gctggtaagg acggaaagac cctctacact tggcggatgt acgcagatag
    32941 cgacaaggga gatgggattt ctgccgtctc aacgggcaaa cgttacctcg gactagccgt
    33001 caatagggag agtgcaacgc cttcaaccaa tcctggtgac tatatctggt catctttttt
    33061 tgagggaacg gaactgggtg gtcgtaatta cattgacgat tacgccatga aggctgtgac
    33121 cttttcatca gtaacctctg agtggaagaa ggaggtaatt gaagatacga gttctgttag
    33181 tggggtgact attaagttga tctgtaccaa agcaggtact ggcggctttc atcggaactt
    33241 ctatgattta aggagtcgaa ttggtgcgac tatgactttt tcaattgata ttaagtgttc
    33301 aaaatctgtc acactcaata tgggttgtga actcggtgga acgaaagctt acgaagtaac
    33361 aacagattgg caaaggtttg tttcttcatg gaaagtaagt agttatcagt actattctta
    33421 tatcttttac ttaaagtcag gttcgtggtc agtaggagat gtggtttatc ttagaaatgt
    33481 tcaattggaa gatggcaacg ttgcttcagc gcctgggcct tctttgaatg atcttatcgc
    33541 tcagattgat accaaagctg acaacgggtt tatgaagcag caattagacc ttctaactga
    33601 aaagacagaa tctctccgag tggaccttga agcgagagct ttggcaaaag aagtagctga
    33661 ttggctcaag tcttataaag agtttgagaa gaataatgaa gctgtcctta cgcaatttaa
    33721 tcaagacttt attgataata cggctcgtat cgcagctatt gaagcagatc ttaaagccaa
    33781 cagtctcttg cttaactttg tcaataccta tttgagagct ggtgataatg gggtaattat
    33841 tggtaagaag gataactctg aatatatcga attaacccca caagggatga tgattaagtc
    33901 agctggtaat gccgttatga cggttacagc tggtgtcatt aaaattcatc atggggtttt
    33961 tgtggagacc ttacaggttg gttattaccg actagaagcc gcaagacata atgctaagca
    34021 tctagtttgt cgttttattg atgccaagta gaaaggagat cctatggcag attatggttc
    34081 aaataatgat aggggctata cattactttt acgagtggaa gaaacaggaa cttcaacggc
    34141 taataataca tctactgtcc gagtccaact ttggctaaag aatggttata cgacctttgg
    34201 gatgtatgac tgtagggcaa gtgtgtctat caatgggcag acgctttctt ggtcagggcg
    34261 accagatatg tatactgctc atagttctct tcacttgatt gataagacca tcactgtgtc
    34321 acatgattcg aatgggtcaa aaaccatcag tttttcagcg accttctctg ggtctggtgg
    34381 ctggtcgcct ggcaccttga atacagggtc acaaacgcta cgtttaagtg atattccacg
    34441 gtcatcgagt gctacagttt ctgggaatat gatggggcaa gccgtaacca ttacgattaa
    34501 gcgcgctagt agtgatttta cccataatat cacatggcat tttggatctc tcagtggcac
    34561 tattgcaaca ggcattgcga cctctgtaac ttggacgcca tcaatatcgc aattagcaac
    34621 tcaaattcca aatagcacct caggtaacgg tcatttaacg ctagctacta tctatggtgg
    34681 taagacaata ggttctatga caattcccat taccctcaac ctaccgacgt cagttgttcc
    34741 aaccttgggc aatatttctg tttcagaatc ccatgccact gcaaaaacga ttttaactgg
    34801 tacgagtttt gcccagttgg tgtctaaccc taaagtgacc ttcaaccaag gagttggtgt
    34861 ttacggatcg actattcctt cgactggttt tcgtgcagag gtctttaagt ttgagaataa
    34921 ccagtgggtt caacttccaa atgtggcaac aagtaataac ggtcttttgg gaggtattaa
    34981 ctggattggt cgcgctaagg tctctgccta tgtgaccgat tcgagagggc gacaaagtgc
    35041 tcgaaaagaa gtggagataa ccttattaga gtatttcaaa cctatctttt cattctcagc
    35101 ggttcgagct ggttctagta tgaatcaggt gacggtcaca cgaaagctta agattgcccc
    35161 tttgactatt agtaatgtcc aaaagaacaa ggcaacgttg acttgggaag tggtcgattt
    35221 ggcaactgga cagaaggtca caaacgcagg tggtgctgcc aactggacgt caacaacgga
    35281 acacacaaag acggctttcc aagctatttt gggggacacc tacgatacga caaagtccta
    35341 tactattatt ggaatattag cggatgtttt ttattccacg acctttgaat ttaccattgg
    35401 tccagaaaag gttgtctatg gcttaagtcc atctggtatg gggataggca aagcttggac
    35461 aagaggggtg cttgatgtgg acgggagttt acctgcttat tttgatggtg agatttatat
    35521 gaagaataag aaacttcttg atatctttta cccagtcggt gtgatttacg agtcgacgtc
    35581 aagtaccagt ccagctacca ttatgggtgg gacttgggag aggtttggca atggcagggt
    35641 cttagttggc gtatctgaga atgaaagtga gtttaatagc attaataagt caggcggtag
    35701 taaaacacat accttgacca ttgatgaaat gccgtctcac tctcatgctc agtatgtatc
    35761 tgccaataat ggcaatcagg ctattcgacg agactactct tcagatggga actctagtct
    35821 ttatcctcaa gggaataaca caggaaatac tggtggcaac aagccacaca ataacttaca
    35881 accttacgtt acggtttacc gttggcgtag gacagcctaa gaaaggaaag tgtcattatg
    35941 aaagaattac tggcaacaaa caaagttctc ttctcagcga ttggagggct tatcggttct
    36001 atttttggag aagttgacgg ggttttatat gcccttttta tttttctcat tattgattat
    36061 gtgacggggt tctttgcggc ggttgtcgag aagaacctct ccagcagcat aggttttaaa
    36121 ggcatcttca aaaagattgc cattctcttt ttggtatccg tgggacacct cattgatact
    36181 gaaatcatca aacagggtgg ggcgattcgc accatggtga ttttctttta cttgagcaat
    36241 gaaggcttaa gtatcttgga aaatgtggtt cggattggct tacctatccc tgagaaactg
    36301 caaaccctct taaaacaatt taatgagaaa gaaggagact aatatgggaa aacatctagt
    36361 catttgtggt catggccaag ggcgaacagc ttatgatcca ggagcaatta acagcaaacg
    36421 tgggataacg gaagctggca aggtacgtga gttagctaaa ctcatgtcca agtacagtgg
    36481 aaaatcgatc gactatatca cagatcaaaa cgtctatgat tatcagtcac tggcaagcct
    36541 tggtaagggc tatgactcta ttaccgaact tcactttaat gcctttaatg gcacggcacg
    36601 agggacggaa gttcttattc aatcctcttt gacagcagac caagaagatg aagctatttt
    36661 aactgtgctt gccaagtatt tcccgaatcg tggaattaag aaggtggact ggctctataa
    36721 tgccaacgtg gccaaagaaa gaggctacac ttatcgctta gtggagattg cttttatcga
    36781 taacgaagcg gacatgacta tctttgaaac taagaaggag gagatagcca aaggcttggt
    36841 gtctgcgatt acgaaacagg aggtggcaac aagcactctt cagcccccct cccaacaacc
    36901 caatcctagt accagtgatt ctacctctgt tgactatctt attggtggtc atgtgcgggt
    36961 tcttcctcat gcgacacatt accaaacagg gcaggcgatt gccacttggg ttaagggaaa
    37021 gacttatacg attgtacaga aaaagacggt aaagcagtca aggagtacga aagcttatct
    37081 cttgtcaggt atccagtctt gggtcttgga acaagacctt gaggtgattc aaaccataca
    37141 tagtgaacaa acctataggg ctcaaaaagg ggatacttac tatgggatag cgaagcgctt
    37201 tggcttgtcg ttagatcaat tacttttagt caatgggttg aagaagactg atgtcctcaa
    37261 gattggtcaa accttaaaag tgcatccttc tagcaaaaca atcactagta tcccaaccag
    37321 tgtggcacaa cgtgtggttg cttcagcctt atctaaggtc ggtcagaaag tgactgtgcc
    37381 aaccaaccct tatggtgggc aatgtgtcag tctagtggat aaaattgtgc aggaagtgac
    37441 tgataagaac atggcttata cgaatgccat tgattgtttg actaaggcaa aggacaatgg
    37501 ctttacagtt attcaagatg cgtggggagt aaacccaaaa gctggagact tctatgtgat
    37561 tgatacgatt ggtatgcctt atggtcacat cggtatttgt atctctgatt ccgatggtac
    37621 aagcattgat ggtgtggagc agaatgtgga tggctattct gacaacaata agaacggcat
    37681 caatgatcaa ttggaaattg ggggtggcgg tatcacacga cgagtgaagc gtgtttggat
    37741 ggcagatggc tcgatttatg atgcatctgg caccgtcaaa cttggtaaag ttatcggttg
    37801 gtttagagta taacagtcag tatttacaaa aaataagcta ccgaatgggt agctttcctg
    37861 atataataaa tagtgtagaa aagtgaagac ggtggctcct gaaaccgaaa gagaggtgat
    37921 gcctatgggc aatccatcaa aatctgacgg agaggaggga gcactttttg accgcttttg
    37981 aagttgtgca gactatctta ggttttggta gctttaccat ttctttgatt ggcttgtgct
    38041 ataaaatctt caaagacgat gataaaaaga aatagccgtc aatactttgg cgagtaacgg
    38101 ctatttctat tagcttataa atgagtcacc gtcctaaacg gttctacatt ggagttggtt
    38161 tgcagaccag ctcctttttc catatcaatt atatcataca ggtagaaatt ttcaagtcaa
    38221 aatgcaaagc gtagtcaaag ggctacgctt tttttatttc ctaaggaaat ttctgactca
    38281 aacctactta gtaaagtaat aagagttaaa acaacggaaa atttttttca ttgtttagac
    38341 taaatcgcat ttttgttccc ctaataggta gagggatata gttagctgat aacttgactt
    38401 attgaggctt tagagtgata tatagtgtgc tgtacatagg gaggatatta aatgacggta
    38461 aagttaatta aggcaaaaca cacccctaaa aaacaacgag tctgtgccta tgttagggta
    38521 tcgaccacta acagtagtca gttggattcc cttgagaatc agatagctta ttttacaaat
    38581 ctatatggca atcgagatga tgttaccttt gtgggtgtct atcacgacaa ggggatttca
    38641 ggttcaactg attatcgccc tagctttcaa gctatgattg aggattgtcg gaaggggcaa
    38701 atagatttga tacataccaa gtctatctca cgctttgcga ggagcaccat gacaatactt
    38761 gaagttagtc gtgagttgaa agtatttggt gttggaatct attttgaaga acagaacatc
    38821 aatacacttt cgagtgaagg agaggtcatg ctttcagttt tggctagtct agctgaagaa
    38881 gaattagaaa gtatgagcgc taatcagcgt tgggcttttc aaaaaaagtt tcaacgagga
    38941 gaaatggtta tcaataccaa gcgttttatg ggttacgatg tggatgataa gggagagttg
    39001 gttattaatg aggaagaagc tttggttgtg agacggattt ttcatctcta tttggatggt
    39061 atgggacttc atcgcatcgc caaacaactc aatcacgaga aagttcctac cgttacagga
    39121 gcaaagtggt atgacaccac tatccgaaat attctaagaa atgaaaagta taagggttct
    39181 gttcttcttc aaaaatattt tcatgatggt gtgaacggaa agaaacgctt gaaccaagga
    39241 caggtggaac aatatcttat tgaagataat catgaggcta ttatttcaaa ggacgactgg
    39301 caagtggttc aggagaaatt aaaccaaaac agtcggaatc aaggaccgaa taaaatttat
    39361 cgttttacag gtctcctcaa atgtcaatat tgtagctcaa ctctcaagcg acaggtttcc
    39421 tacaagggaa agattgtctg gtgttgttct aagtatatta aagagggtaa aatttcctgt
    39481 caagggatga gagtgcctga aaacgatata aatgattggc aaatacagac agcagtaacc
    39541 gtaatagaaa ggattgaaga tgggcaaaaa cattacagtt attccagcaa agaaggtaca
    39601 ggtaacaacg ctacaccata tcaaagagaa aatcagagta gccgcctatt gtcgggtgtc
    39661 caccgaccaa gacgaacagc tatcaagcta tgagaaccaa gtcaggtatt accgagatta
    39721 catcttaaag catgaggatt atgagcttgt agatatctat gcggatgaag gcatttcagc
    39781 aaccaatacc aaaaaacgtg atgcctttaa ccgattgata caagattgta gggctggtaa
    39841 ggtggatagg attttggtca agtcgatcag tcgatttgcc agaaacaccc ttgattgtat
    39901 caaatacgtc cgagagctga aagaacttag tgttggtgtg acttttgaga aggagaatat
    39961 tgacagcttg gattccaaag gtgaagttct ccttacaatc ctttcttcgt tagcacagga
    40021 tgagtcacgc tctatctcag agaatgcgac gtggggaatt cgtaagaagt ttgaacgtgg
    40081 tgaagttcgg gtgaatacca ctaagttcat ggggtatgac aaagatgaga atggtagact
    40141 catcataaac ccagtgcaag cagaaacagt aaaattcatt tacgagaaat tcttagaagg
    40201 ctatagtcct gagtccatag ctaaatattt gaatgacaat gaaatacctg gttggactgg
    40261 aaaggcaaat tggtatccaa gtgctataca gaagatgctt caaaatgaaa agtataaggg
    40321 tgatgcctta ttacaaaaga cttttaccgt tgattttctg actaagaaac gagttcaaaa
    40381 tgacggtcag gttaaccaat actatgtaga aaatagccat gaagctatta ttgacaaaga
    40441 cacatgggaa ttagtacaga tggaattgac aaggaggaga gactttcgag aagaacatca
    40501 actgaaagct tacatcatgc aaaatgacgt taatcctttt acgactaagg ttttctgtgc
    40561 agaatgtggt tcagcctttg gacgaaagaa ctggaccaca agtcgaggta aacgcaaggt
    40621 ttggcaatgt aacaatcgat atagggtcaa aggacagatt ggctgtcaga ataatcatat
    40681 cgatgaagag acgttagaga aagccgtagt aatggctgta gaactattga gtgagaacgt
    40741 agatctattg catcggaagt ggaataagat tctagaagaa aatcgtccgc tagaaaagca
    40801 ttatagctca aagttggctg aaatgataaa caagccttca tgggaattcg attcgtatga
    40861 gatgtgtcag gtggtggaca gcataacaat tgcggaagct gggcagataa ctgtcagatt
    40921 tttagaagga actgatgtag acttgtaagt gattgtgact gaaaggttac ggtttttctt
    40981 tgactttgtg t
//
LOCUS       DARYSY010000017        38390 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYSY010000017 DARYSY010000000
VERSION     DARYSY010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38390
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            28..783
                     /locus_tag="TVR04_000768"
     CDS             28..783
                     /locus_tag="TVR04_000768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269473.1"
                     /translation="MRKTLLVILSFMLMTISLNFLYINVKAMTDTEWRKSFGGNYGQD
                     DYTTPPPLVGNQAKIGFQNDWEKARDFGVKPINVGDQEIMIKTAPGAIIRISKNGTEL
                     YEISLESTAVNSGYIIKPTLANSSGTVTFKLTNSGTYENQEIKKNSEEKVKIGDKYFV
                     SVSYDGINLGSAEWTVGESIPKDIEEKDEEEIQKFVEALENKEKEKADREQKYAEALF
                     RNAIATEANKTWYQRLGDSIEDTWANVKGWWKG"
     gene            complement(997..1554)
                     /locus_tag="TVR04_000769"
     CDS             complement(997..1554)
                     /locus_tag="TVR04_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1269474.1"
                     /translation="MLGLVWWKWSVADRPQPKQVKEVMTTAATKASVPHKEKMESKEP
                     ETSYQPEAYPDLTSYQELSVHVSIADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFV
                     IEPERGDFFFNQASEEGAYYWVSFKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHG
                     CVRMSRADAKWFYENIPEGISVTIE"
     gene            complement(1697..4348)
                     /locus_tag="TVR04_000770"
     CDS             complement(1697..4348)
                     /locus_tag="TVR04_000770"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1269475.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSDDKKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEMYVGEEAPEGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDTDAEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDQEGRKMSKSLGNGIDPMDVIETYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQATANVEQVVSGAAGNVTDRWILHNLNETIGKV
                     TESFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVTPVFENAAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFKANVNYIKRFTNPERLEIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            complement(4361..4924)
                     /locus_tag="TVR04_000771"
     CDS             complement(4361..4924)
                     /locus_tag="TVR04_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1269476.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELETDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKAPENLKHY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            complement(5124..5708)
                     /locus_tag="TVR04_000772"
     CDS             complement(5124..5708)
                     /locus_tag="TVR04_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269477.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLVDVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLGF
                     TLEAAIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            complement(5968..6468)
                     /locus_tag="TVR04_000773"
     CDS             complement(5968..6468)
                     /locus_tag="TVR04_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1269478.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAKKAAQPKGDVASSSLADSSKVSSEKEISKTSSEVL
                     SRDAFAELAEVSELRADIVAVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            complement(6490..6744)
                     /locus_tag="TVR04_000774"
     CDS             complement(6490..6744)
                     /locus_tag="TVR04_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1269479.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSQQIAEEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            complement(7112..7182)
                     /locus_tag="TVR04_000775"
     tRNA            complement(7112..7182)
                     /locus_tag="TVR04_000775"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7148..7150),aa:Thr,seq:ggt)
     gene            complement(7454..7624)
                     /locus_tag="TVR04_000776"
     CDS             complement(7454..7624)
                     /locus_tag="TVR04_000776"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269480.1"
                     /translation="MFKYLKGILYLLAPRLAFSVTGILFPDAFDSLFLVYHVLMTIAF
                     WLAIYSLDLPEK"
     gene            8058..8813
                     /locus_tag="TVR04_000777"
     CDS             8058..8813
                     /locus_tag="TVR04_000777"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1269481.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQVRQAAASAKALGY
                     KYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            8872..9954
                     /locus_tag="TVR04_000778"
     CDS             8872..9954
                     /locus_tag="TVR04_000778"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1269482.1"
                     /translation="MTQTLQVKSRITDYPIIFADDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEASRIYDQLIRANFSKKDIIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYISFPIAKHDRRLLDWLRSLLDIA"
     gene            complement(10286..11059)
                     /locus_tag="TVR04_000779"
     CDS             complement(10286..11059)
                     /locus_tag="TVR04_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1269483.1"
                     /translation="MILTQFDPEYQAIINPKDLVAEIDNFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(11179..12063)
                     /locus_tag="TVR04_000780"
     CDS             complement(11179..12063)
                     /locus_tag="TVR04_000780"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1269484.1"
                     /translation="MLERLSGHTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVDNSGLAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALVGAVNTVVNTDGK
                     GHLVGHITDGTGAIRALAEEGVAIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQVLKGINAKTSALASLQDLADDRAFRRSIAESSIYIDATGVGMKPLEEH
                     SLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCRDKE"
     gene            complement(12203..15625)
                     /locus_tag="TVR04_000781"
     CDS             complement(12203..15625)
                     /locus_tag="TVR04_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1269485.1"
                     /translation="MSLDAITGPMDQSHGDTYQLHWIDKAGRCHAFSKGWRFLMADLQ
                     LAQEPLFDDSDWQQIALPHDFSINQPYTINGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHQVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEIELGLSQQVPLSDYQLSLSL
                     SEQLADTQQGQTVYESKPVALGLLEESGRLVMTIPLRHIKLWSPAQPQLYQLDMLLYH
                     KGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAYEEAIARQ
                     LVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSHDFSSHFH
                     KTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPAVLMWSIGNELLEGFSADVSH
                     YPYVAKELCQWIIELDQSRPITFGDNKLKDQHFHWAQETKALAEQVNQLQSVQGVIGL
                     NYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYDQSTVDWG
                     ALASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQSYFGILDT
                     AGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAASVRILFDD
                     GHGGQIDYGIKALTRHETPAGHCYQLYEGDDAAESPHQNLYLTWKLPYRSGSLRAIAY
                     DDKGQVITQTSGRSCVSSYQQPAQLFWSCFEPPKLLAEPSLLYLDLSLLDAHQTLVAN
                     ANLLINIEVEGPGMCLALDNGDPRDHQPYSSLSRQAYGGRLLAIIALDGRAGQLKVTA
                     RAQGLQEASYQLTVAEAAIKEKLLAYRLDKYSFITDKTKRQLKADPRPISQGSDDFAP
                     AADYYVSCQSHCLSDRPVMMFSYATVFTEPLTFQPLTQRLIKGKDIFLPSWLQPKTAA
                     GHLLTKAFPIDWQLAAPVFTEESRVSGQTSCFGQSLKLEAILKPDTKGLRINQELSLV
                     AKKKLLCQSDTQLSYRYQYDTVQAIGAISLTGLKKPLASLRLVLDYRSSSSAPSKRLS
                     LSLDQVEQPCQYILLDSVLDVLSLDLTLEQPVGQAFALESLKLGLWSMAEEA"
     gene            complement(15639..17123)
                     /locus_tag="TVR04_000782"
     CDS             complement(15639..17123)
                     /locus_tag="TVR04_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269486.1"
                     /translation="MYKVLLVDDEYMILQGLKVIVDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARNVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPETELLGFTVLYVDCKAFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSLFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKALMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRMTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQCFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            complement(17123..18847)
                     /locus_tag="TVR04_000783"
     CDS             complement(17123..18847)
                     /locus_tag="TVR04_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1269487.1"
                     /translation="MTNKSLKRFVIEHLKQGFLINRLMKLYSLFIVALFSLSAIGLST
                     YSIRNTYQMVDNQMQMRLDETLTKLQSQNYITLRVLEQLVGRPEDYHNLYQYMLLTPN
                     QYFTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTAYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGQLYLHFTDPGTILQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIKQVSDITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYIQEIYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEMPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEGDSILIQVLDN
                     GKGISSERLMTIEEGLQVPQATGNSSIGLQNVYMRLFHQYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            complement(18837..19442)
                     /locus_tag="TVR04_000784"
     CDS             complement(18837..19442)
                     /locus_tag="TVR04_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1269488.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNAKQFLLTLMVLAGV
                     AWFTWQYKGLYLFLSFGALVVLLDIATKPNRYMIDGVIDDQ"
     gene            complement(19790..21235)
                     /locus_tag="TVR04_000785"
     CDS             complement(19790..21235)
                     /locus_tag="TVR04_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1269489.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEAVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            complement(21319..22245)
                     /locus_tag="TVR04_000786"
     CDS             complement(21319..22245)
                     /locus_tag="TVR04_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1269490.1"
                     /translation="MEKKKTVKKVNVRTFDQKTNVVFNVLIAFFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTIWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(22255..23205)
                     /locus_tag="TVR04_000787"
     CDS             complement(22255..23205)
                     /locus_tag="TVR04_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1269491.1"
                     /translation="MTTKTSSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            23438..24331
                     /locus_tag="TVR04_000788"
     CDS             23438..24331
                     /locus_tag="TVR04_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1269492.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQAVNDGKSYTGKEVLELADQGDPVALKEKQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            24319..26493
                     /locus_tag="TVR04_000789"
     CDS             24319..26493
                     /locus_tag="TVR04_000789"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1269493.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     VLGCVQNITDCRDKDLTMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEHSRKEWLSYLNRIDIKDKDFDKV
                     KTYYQHFYRALLFPQRWYEITPAGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAATLGKIQLSSQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGKAAFAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCQGNVPQYQFVKELKLNQA
                     SYNKLYINHDDLIQGCQLDFHLGLAPPLKDYLAEDLPYSLTR"
     gene            complement(26813..28204)
                     /locus_tag="TVR04_000790"
     CDS             complement(26813..28204)
                     /locus_tag="TVR04_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1269494.1"
                     /translation="MLEFPEGFWWGGATSGPQSEGRFQKPHRHLFDYWYEQRPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICAYREQAAELSNGS
                     VGTILNLTPIYPATDSEAALAAAHVAELWHNDLFMSAAVCGSFPGELVAMLKRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYHPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGVSGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPIDCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            complement(28231..29925)
                     /locus_tag="TVR04_000791"
     CDS             complement(28231..29925)
                     /locus_tag="TVR04_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1269495.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLAASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFKDLIQLAKERQVDFWYMISPGLDFDYTKK
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYHIVDAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDEAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALVRKDIASLSAWVAEVVELVDKLKKLDIPEFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYADLQEQKHRIGSNIPSRFYQLHYLQENSMLGNQVQVAEARTEDYT"
     gene            complement(29940..30998)
                     /locus_tag="TVR04_000792"
     CDS             complement(29940..30998)
                     /locus_tag="TVR04_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1269496.1"
                     /translation="MTELLYKKIYHFIKRQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TIVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATSEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIEQLTRSDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            31131..32417
                     /locus_tag="TVR04_000793"
     CDS             31131..32417
                     /locus_tag="TVR04_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1269497.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     TYDDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDASMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETGCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSKGETIYAYEVDGMGHYAIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSSENP
                     YYYQGSAASGIGSSHTPKNYIWHIALALQGLTALDQKDKANMLDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            32432..35158
                     /locus_tag="TVR04_000794"
     CDS             32432..35158
                     /locus_tag="TVR04_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1269498.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPEREADIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCDKWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKRARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYEFVHSCFEDYLADLSQELPEEL
                     STVAGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENVTEPLATMAFEVTGTYP
                     HEQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKVFPFGQRLPKAVYQEAKEYLETRQP
                     QFQAIDAAGRVIEEAEILGTDITFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQAADTDKMLFHQDRSCLENEFLKVIIAANGLLTIEDKLNGNTFDSCLQY
                     EDCGDIGNEYIFRQPDHDIPYLAHQGSCKLRVLTNTAHLAEIELTQTFDIPLAADDRL
                     QAEMEAVIDIRERQAKRSQEKAPFTVKTVIRMEKESPRLQFQTSFDNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPSNPQHQEAFVSLFDGRTGVTVGNEGL
                     SEYEILPETNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQIPVTMAQTKSHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDEACAFTLAIPDHTARVTSLLEEDQHEPLPAELGKGDILTLAWKKSESAHL"
     gene            complement(35415..36023)
                     /locus_tag="TVR04_000795"
     CDS             complement(35415..36023)
                     /locus_tag="TVR04_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1269499.1"
                     /translation="MIEIKQLSKHYGKKTIYDKISLTFETNRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGEEIWSMKEQDYFKRYLGYVFQNYALIEEETVYDNLKILAP
                     KPKIVEALHSVGLDSSFLSQCIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(36020..38023)
                     /locus_tag="TVR04_000796"
     CDS             complement(36020..38023)
                     /locus_tag="TVR04_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269500.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTAYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTELGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRRELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKRATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDTAKDFAEITWLETLSAHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDSEVIYSEPSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAAGVIYIPKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPNGQKSFLFNHKQDQQDIFAQQEEVDTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLMNVSGLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWSLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNSLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
BASE COUNT        11074 a         8920 c         7851 g        10545 t
ORIGIN      
        1 ttatcaagat taagattgga atgtaagatg aggaaaacat tattggtaat attaagtttt
       61 atgcttatga caataagtct aaactttctt tatatcaacg taaaagcaat gactgatact
      121 gaatggagaa aaagttttgg tggaaactat ggacaagatg actatacaac accacctcct
      181 ttagtaggaa atcaagcaaa aattggtttc caaaatgact gggagaaagc aagagatttc
      241 ggtgtaaagc ctattaatgt aggagatcaa gaaatcatga tcaaaacagc tcctggagca
      301 attattcgga tctctaaaaa tggaactgag ctatatgaga tatctcttga aagtacagct
      361 gttaacagtg gatatataat taaaccaaca ttagctaatt cttctggtac tgttacattt
      421 aaactaacta actcaggcac ttatgaaaat caagaaatta aaaagaattc tgaagagaaa
      481 gtaaaaattg gagataaata ttttgtatcc gtaagctatg atgggattaa tttaggctca
      541 gcagaatgga ctgttggtga atcaattcca aaagatatag aagaaaaaga tgaggaagaa
      601 attcaaaaat ttgtggaagc attagaaaat aaagagaaag aaaaggcaga tagggaacaa
      661 aaatacgcag aagctctgtt cagaaacgca atcgctacag aagctaacaa aacctggtat
      721 caacgtctgg gcgatagcat tgaagacact tgggctaatg tcaaaggttg gtggaaaggc
      781 taatcatatc gtttcctcgc tttgatttct gcaagtaata tactccccta aaaaacactt
      841 tgctagaagg ctagttactt gtcttctctt agatcaatgg acctgtttca ggtctttttt
      901 cgttcctttt tgcagtcttt taaggagctt taaaagcctg ctaatattaa caggctcttc
      961 ctctatctgc tcaggctatt ctgagggaga ttagggctat tctattgtga cgctgatgcc
     1021 ttctgggata ttttcataaa accatttggc gtctgctctg ctcatgcgga cacagccatg
     1081 tgaggctggc tgtcccagtc tctctgcctc ctctggaatc tcattgccat attggtctgt
     1141 tggtaggcta tgaaacagat aaatcccatg gtccttaaag gacacccaat aataagctcc
     1201 ctcttctgat gcttgattga agaaaaagtc tcctcgctca ggctcaataa caaaggtccc
     1261 tgtcggtgtt ggactttcct ttgctcctgt tgacacgctg gtcttaaaaa taaccttacc
     1321 atctcctata atggtcatga cttggtctgc aatcgacaca tgaacagata actcctgata
     1381 gctagtaaga tcaggatagg cttctggctg atatgatgtc tcaggctctt ttgattccat
     1441 tttttcctta tgcggcactg aggcctttgt cgctgctgtg gtcatgactt ccttgacctg
     1501 cttgggttgt ggccgatctg ccactgacca tttccaccat accagaccaa gcataagccc
     1561 tattaccagc acacctaacc aaccaatgac tctttttttc atgagacact cctttgactt
     1621 atatagataa ttgtgatgat tactccttga cagtatatca aaaaaagagc caattggctc
     1681 ttagatgatc actatcctac cttactaact tctccatttc cttaatgcgc tctactgttg
     1741 catcgtattt agcttggtaa tcagcctgtt tgtcgcgttc tttttggacg acttctggct
     1801 tggcattagc aacgaagcgt tcattgctga gctttttacc gaccaggtca agctcttttt
     1861 gccacttagc taattctttt tcaaggcgcg ctaattcttc tgtgacattg agcagatcag
     1921 ctaggggaag gaagatttct gcacctgtga taacagccga catggccaac tcaggagtca
     1981 caatacttga agcaatctca agtctctctg gatttgtgaa gcgtttgata tagttcacat
     2041 tagccttaaa gaaggcttcc aagtcgctat cgcttgtttt gacaaggata gtgattggtt
     2101 tacttggtgc tacatttacc tccgcacgcg catttcgcac cgtacgaatc aagtccttca
     2161 agctttccac gcctttgtgc gcagctgcat tttcaaacac aggagtcact gttggatagg
     2221 ctgctgtcac gatagagcct tcagcgtatt ggccaaagat ttcttctgtc acaaatggca
     2281 tgattgggtg gaggagacgc agaatcttat ccagcgtgta gaggagaaca gagcgagtga
     2341 taaccttctc gtcttcgttg tcgctgtaca gaacctcctt ggtcagctcc acataccagt
     2401 tggcaaattc ttcccagata aagttataga ggatatggcc tgccacacca aactcaaact
     2461 tatcaaagct ctctgtgacc ttaccgatcg tttcgttgag gttgtggagg atccagcggt
     2521 ctgtcacgtt accagcagcg ccagacacaa cttgctcaac attagcagta gcttgctcaa
     2581 gtgtcaagcc ttcattattc ataaggatat agcgtgaaat gttccagatt ttgttaatga
     2641 aattccatga cgcgtccatc ttttcatagg agaagcgcac atcttgacca ggagcagatc
     2701 catttgatag gaaccaacga agagcgtcag caccgtatgt ctcaataacg tccattgggt
     2761 caatcccatt gccaagcgat ttagacatct tgcgtccctc ttggtcacga atcagaccat
     2821 gaataaggac gttagagaaa ggcttacgcc cagtaaattc aagcgattgg aaaatcatgc
     2881 gagacaccca gaaaaagata atgtcatagc ctgtcaccaa ggttgaggtt gggaagtagc
     2941 gcttgaagtc ttctgcatct gtatcaggcc agcccatagt tgaaaatggc caaagcgcag
     3001 agctaaacca ggtgtcaagg acatcctcgt cctgcttcca gccatcaccc tctggtgctt
     3061 cctcaccaac atacatctca cctgcttcat tgtaccatgc agggatttgg tgcccccacc
     3121 aaagctggcg agaaatcacc caatcatgga cattttccat ccattgcaag aaggtatcgt
     3181 tgaagcgtgg tgggtagaag tcaaccttat cgtctgtgtc ttggttggca atagcatttt
     3241 tagccaattg gtccatcttc acgaaccact gtgttgacaa gcgaggctca accacaacac
     3301 ctgtacgttc tgaatgacct actgagtgaa cacgtttttc aatctcaaca agggcaccga
     3361 tttcttctag cttagccaca acagccttac gagcttcaaa ccgatccata cctgcaaatt
     3421 cacctgcaag ctcattcatg gtaccatcat cattcatgac attaacctgt gggagattat
     3481 gacgcccacc aacctcaaag tcgttcggat catgggctgg tgtgatttta acaacccctg
     3541 ttccgaatgc cggatccgca tgctcgtctc caacgattgg gatgagctta ttgacgattg
     3601 gcagaacaac atgttgacca atcaagtcct tgtaacgagg atcttctgga ttgacagcga
     3661 cagccacatc tccaaacatg gtttcaggac gtgtggttgc tacttgaagg gcacgtgaac
     3721 catcttctag catatagttc atgtgataga aggcaccctc aacgtcctta tggataacct
     3781 cgatatctga aagagctgtc ctagctgccg ggtcccagtt gatgatgaac tcaccgcggt
     3841 aaatccaacc tttcttgtaa agctcaacaa agaccttgcg aacagccttt gagagcccct
     3901 catcaagagt gaagcgatct cgcgcatagt ctagtgaaag cccaagcttg ccccactgct
     3961 ccttgatggt tgctgcatac tcgtccttcc attcccacac cttgtctagg aacttgtcac
     4021 gaccgagatc gtaacgggaa atcccctgct cgcgcaggcg ctcctcgacc ttggcctgag
     4081 tggcgatacc tgcatgatcc ataccaggca accagagggt gtcaaagccc tgcatgcgct
     4141 tttgacggat aataatatct tgaagggtcg tgtcccaagc atgaccaagg tgcagcttac
     4201 ctgtaacgtt tggcggtgga atcacgatag aatacggctt agccttcttg tcgtctgatg
     4261 gcttgaaaac atcttggtcc agccaagctt gataacgccc agcctcaacc tcagctggat
     4321 tatattttgg tgaaagttct tttgacatat ggtgtccttt ctagcttact tctaactctt
     4381 tcattttttg gacgataaac tgcgctgttt cttgagcaga aagactcgta ttattgattt
     4441 tacaataatg tttaagattt tctggtgcct ttgcagggtt aaagttagca aatttagcag
     4501 tatccaaaat atctttctca gaccactcca aatgacgctt tatcggtttg tggtaaagtc
     4561 gattttcagt tttatttcgc cttaagcgtt cttttaaatc tgtttctaat tcaacgaata
     4621 aaacctctct gtcgaaatca tgaaacacac tctgtagtgt ttccaaaaat gctatatctt
     4681 caggtgcatt aaaatcaatg acaacagtaa aaataattga ttgctgacgt tttgcaaatg
     4741 ttttaaaaaa tagcaatcgt agctcatcaa ttagttctct agcttccgat gacattggta
     4801 taaacttagt cacaaaatca atcgattcat gattatgaaa taaagtcagg tcagtcagtt
     4861 tttctaattc ctgtccaatt gtcatcttac cagacgcctg tgctccaatt aagataatat
     4921 tcataccaaa cctctttccg atctctctta cctcttctca cctcacttaa cataacactt
     4981 gctgctcaag gcagactacc agaaactgat gacactggtt ggcgaagcgc taaccagttt
     5041 tggtagtcat aagcgctttg agtttgagga cttcttatga aatgcttttg acaaactaac
     5101 acctatttta gagagtctgc tccttatcta cactgcctct cccattctct tttcaacagt
     5161 ccatagcgca agtctgcgca gcgattgcct ttagcgtcct tgcgatcacg aatggccgcc
     5221 tcaagagtga agcctagctt ttctgcgatc cgacgactcc ccatattgta atcgtaacag
     5281 ctgatttcaa ccttgtgaag cttaagcaga gtaaaggcaa cctctagcag ggcactcgct
     5341 gcctcagtca taattccttg atgccaatag tcagggtgaa gcagatagcc catctcaaaa
     5401 acatcatctg cgtgacggtt gttaaaatca acagacccaa taatcctatt gtcacccttt
     5461 agggcaatgc catagcctgc cggtagctgt tgcaaaagcc agcgcttagg catcgtgttt
     5521 gcgatgtaat gctcctcttc ttcaagggtt ttcacaggtg gaaagcctgc tgggtaacta
     5581 acctcaggtc ggctagcata agcaaaaatc gcttcaacat caactaaagt acgctgccgc
     5641 agcagcaaac gactcgtttt gacatctggt aatctattat tctcaacaga acccattatc
     5701 tcaatcatag caagtcctcc aaaaaataac cccgcctagt caatcgacta gacagggacg
     5761 aattcactaa taatccgcgg taccaccact gtttcagatt acacttaatc tgctgcttta
     5821 tcatttttcc attgtaagcc tcagctacat aacttgacat ctgtgcggat ttctcaacac
     5881 caccgctctc tgtaacagac aaactcaaga tacctctgat tgctaacatt ctaacaaatt
     5941 tatacttatt aagcaataaa aatcagacta ctttttaaag ttgacaccat tttcctttag
     6001 cttgctgata gtcgctggtc caattccctt aagcgccaaa agctctgcct ctgtccattg
     6061 gctaaaagca gcagctgacc taataccagc ctcaaaaagc accgcaacaa tatctgcccg
     6121 aagctctgaa acctctgcca actctgcaaa agcatcgcgt gataagacct cgctactagt
     6181 ctttgagatc tctttttcac ttgaaacctt agaactgtca gccaagctac tagaagctac
     6241 atctccttta ggctgagctg cttttttagc aatgctctgc ttatcctgta gatcagcagt
     6301 ctctgtcttt gatgctgtta ccatttgtga agcggtatgc actgcttctt tagtcttatc
     6361 aaccaccttt tccacagtct gctccacttg attgattact gccttgagca gtccttgacg
     6421 cttaagctgt agcttgtatt gttttttacg attgtatcgt cttgccatga ttactgctta
     6481 tcccttcctc taataatgac ggctaccaaa taggctgtct ggcacctcat gaaaagcttt
     6541 acctttatta taattatcaa attttcctaa taaaaactca taggcatcta gcttactttc
     6601 ataacgaata aaggcatctc tggctctttg atcattatct tcctctgcaa tttgctggct
     6661 cgttgccata gctagctggt tgacctgaat ttgagccttc acccagtctt caaaatccct
     6721 taaaaagtct tgctcataag acatgtctga ccccctcttt ctgacttaat ccttaccatt
     6781 ataccacagc ctgacttatt gtgctatttt cttagaagct cataataaca acaactataa
     6841 ggcagtctga cttgctgatg attgactaat acaaagtctt aaaacgaagt taagctgttg
     6901 aggagagctg atgactgtct gttgggcagt ggtcagggag actgtcaagc gatacctgat
     6961 gtattgacag aactggtagc atcaagtgat ttggcgtcgc agacagctta gacgaacaga
     7021 agtcattatg gtaataattc acagatgacc actattggtt cacctagcaa ttaaaaaaac
     7081 tgtcctaata agacttagga cagtactcag atgccaccac cgagaatcga actcggaacg
     7141 aagcattacc attgctttat tataccattt aactatagcg gctaccttcc tatgatacta
     7201 taacttgttt tggtgtgcaa gtcttttttt aaaaaaatgt cattagtgtt ctgatttttt
     7261 cttgtgcatg ctatagtggt ggagtagaaa agttaagacg atggctgctc gttctgaaag
     7321 agccttgagg tttaatcaat tgaaatagaa gcattttgac agctgtactc atgatggcta
     7381 tcatagctca gacgcttctt ctgttaacgt atcagctacc ttttgtcaac taaatacaaa
     7441 acaagtcccg caactatttt tctggtaggt caagagaata aatggcaagc caaaaagcaa
     7501 tcgtcattaa cacatggtaa accaagaata ggctatcaaa agcatcagga aataatatgc
     7561 ctgttactga aaaagccaat ctaggagcta atagatataa aatccctttt aaatacttaa
     7621 acatctacca ttacctctgt ttctaaaatg atttgctttc tattattaat atacaccaaa
     7681 aaaacgatat atgtaaacct tttctttgtt gtgtttaaaa aactaaactg ttccacaata
     7741 aaagctatag ctagtctcat catgacactc aatcatcagc actttttcac tgtacttgcc
     7801 tattccagct aataagcatt cgcaacagct ctagcagctg taaaacctct acctgagagg
     7861 gttaggaggc tcaaaagctt ctcctctggc aacgagctga tctctcttat tagcttgaaa
     7921 tttaagcttg attatggtat gatttcccaa gctatgaata gttctgtcat gccttattca
     7981 cagtattatc taagacagag ctgtcatctt acctttgggg aatcattctc tcaatatcat
     8041 attaggaaag agtataaatg ggaaacgata taatagctga ttttttaaac aagggctgtc
     8101 aaaagagtaa ctttattgtc ggtccctgcg ccattgaatc ttatcagcaa gtcagacagg
     8161 cagcagcaag cgccaaggct ttaggctaca agtattttcg agggggagcc tataagccca
     8221 gaacctcttc taactccttt cagggcttag ggctgacagg ggttacctat ctacatgagg
     8281 tttgccagga attttcgctg aaggctgtta gtgagattat gtctgaaagg cagctagagg
     8341 aagcctatga ctatttagat attattcaga ttggcgctcg aaatatgcaa aattttgaac
     8401 tgttaaaggt attgtcaaag attgacaagc ctatcttgtt taagcgagga ctaatggcaa
     8461 ccattgagga atatttgggt gctttatctt atttacaaga aaatggcaag caaaatatta
     8521 ttttatgcga gcgtggggtt cgtggctatg atgtggaaac tagaaatatg ttagacatca
     8581 tggcagtccc tattattcag caaaaggtga agctgccaat cattgttgat gtctctcatt
     8641 ctaccggaag aagagattta ttattgcctg ctgctaaggc cgctaaggct attggtgcca
     8701 atggtattat gatggaggtg caccctacac ctgatcttgc tttgtcagat gccgcacagc
     8761 agattgacta tcaacagcta gagcagcttg gaaaagagct ttgggaaagc taactaacag
     8821 cagccacagg tccagtcatt cggactgatg gtgcttagga gagaaagacg catgacacaa
     8881 acacttcagg ttaagtctcg tatcactgac tatccgatta tctttgcaga cgatattttt
     8941 cagccgctga atcaatttct tgctgaaaaa ggagatgtca agctattgtt tatcactgac
     9001 caaacggtat ttgatttata ccagccttta tttagacgtt ttcaacagga ttacgatagt
     9061 tatcttcata ttgctgctcc aggggggcaa tctaaatctc tagaggaggc tagccgaatt
     9121 tacgatcaac tgattagagc taatttttct aagaaggaca tcattgttac tgttggagga
     9181 ggggtgattg gagatcttgg gggatttgtt gcggcaacct tttaccgcgg gatttcctac
     9241 gtccagattc caacaacctt acttagtcag gtagacagca gcattggtgg taaggttggg
     9301 gttcatttta agggcttgac caatatgata ggcagtatct accctccaaa ccagattatc
     9361 gtgtcagcca agtttttaga cacgctttct gagagagaat ttgcctgcgg catcagcgaa
     9421 atgattaaaa ttggttttat tcatgatcgt aagctctttc aacagctcct agccttcccc
     9481 aaggaccgca atcaagagca gctcaggcaa atgatttttc aagcgatttg ccataaaaaa
     9541 agagtggttg aaaaagatga atttgaaggc aatctccgca tgtccttaaa tttcgggcat
     9601 acgctagggc atgcgattga agccttatgc catcacgagc tttacaggca tggtgaggct
     9661 attgcgattg gcatggtctt tgaggccaag ctggccgtcc agcagcagct actgagccaa
     9721 caggatttag aggcattaca ggctgccttt gaggcttatc agctaccgac cacacttgag
     9781 gctaagtcaa tgacagccga agccttgatg actgttttaa aaacagataa gaaaaattct
     9841 ggtcagcata ttgtcctcat tttgccaacg acgaaaggct atataagctt tcctatcgct
     9901 aagcatgaca ggcgcctgct ggattggcta agaagcctgc tagatatcgc ctgagaaggc
     9961 ttttctcctg tcttattagt cgagtgaaaa aactgctgct tctgaaaaac aaaaaggctt
    10021 caaagcctct tgtttactga gtcttttgat gagaaaagac cacttttttc acagtaaggt
    10081 gaaaggccta agcttcattg ctttgtccct aggtgaatgc taaggcatag gtataagaag
    10141 cataggctac tctaaacatt atattaacat gcagaggtga gctgtttgca tgacacctta
    10201 acagcacctt gagctgaact gatctcccag gcgttagagc cttaatctaa ccttttggag
    10261 gcacttcata gctcttgatg cttttttagt tatccttaaa taatcgtaag gccaactcta
    10321 aggcaataaa ggcaatgtta tcctttgcct ctaggtctgc ttcattggct aagcttcttg
    10381 cgtcccactc atcagcatct agattatcag cggaataaaa aaactgaaaa tgctctagct
    10441 gtctgaaggc tgctagggcc gcaatagcag agcattccat gtcaacacag atagccccct
    10501 cctgctttcg ttgaatcatc ttgtctctag tttctctata aatcccatct gttgtccagg
    10561 tcttaccaag ggtataggtc tgggaatgct gttctaaaac atcaatagcc cttgttaaat
    10621 aagcttgatt cactgcaatg tcatgactag caggctgata gtggtagctg gtcccttcgt
    10681 ctcgaatagc actagttggg ataataatag agttttcact gatagtagcg tctaggactc
    10741 cacaggtccc aaaaaccaag agctgcttca ttcccatagc aatgatatcc tctaaaaccc
    10801 caacgcagcc agctgctcca acgtaggaat tgaaaaagcc aagcttatgc cctttaacat
    10861 ctaattcgta tattggaata tcaagattag caacgcttgt tgtggctatc agtcgatgcg
    10921 gcagtgcatt aagtacccta ttaaaggttg ctcttgcaaa gcaggtgact actgttttag
    10981 gaaagttatc tatctctgcc acaagatcct tagggttaat gatagcttgg tactcagggt
    11041 cgaattgtgt taatatcata ggctgctcct ttgcttttgg tgctttttat tataaataaa
    11101 atgctgataa acctcaagac caagcaaaga gctgagcgat taaccttttt ttcctatacc
    11161 ggcgtgagca gcagacattc attccttgtc acgacacaaa agctctcgga tataggctac
    11221 cggcatgtct tcacctgtca tcagcttaaa ggcttctgct ccttggtaaa ggagcatgcc
    11281 taggccattc atcacttttt tagccccatg ctcacgcgca aaggctagga gctttgtttc
    11341 tgctgggtga taaacaaggt caaaaaccac aagatctgga cgaataaggg ctggatcagt
    11401 aatcaggcta tgctcctcaa gaggcttcat gcctacacca gtcgcgtcaa tataaatact
    11461 agactctgca atagaccgcc taaaggctcg atcgtctgct aagtcctgta ggcttgccag
    11521 agctgaggtc tttgcattta tgcctttaag cacctgcttg gcctgcttga aggtggctgt
    11581 ttttcgatta aatagtcgaa tttccttagc accatcaagt cccagctgaa cagcaatggc
    11641 tgtgcccgca ccgcctgcac cggcaatcgt aatgatctga tcctttatcg caacaccttc
    11701 ttctgctaag gctcgaatag cacctgtgcc atcggtgata tgaccaacaa gatgaccttt
    11761 gccatctgta ttaacaaccg tattaacagc tccaactaag gctgcagccg gtgatagctc
    11821 atcaagcaag ggcacaatgg cctgcttatt tggcatagac acatttgcac cgcaaatgcc
    11881 caaggcacgc atgccctgta ccgcagctgc tagtccacta ttatcaacct caaaggctag
    11941 ataggcatag tccagcccca gcttagcata agctgcattg tgcatttttg gcgataggct
    12001 gtgacgtgcc ggtgctgcca gcaaagccgt caatcgtgta tgacctgata acctctctag
    12061 catcaaatac ccctccttta catcatatca ggcgatgctt attttgctac taacctagca
    12121 aagctggcta ggcatttact gtcattatac cttattttta aaagactgtc ttaatgataa
    12181 tatgagctgg taagcttgaa gcctaagcct cctcagccat actccaaagt ccaagcttaa
    12241 ggctttctaa ggcaaaagcc tggccaactg gttgttctag cgttaagtct aagcttaaca
    12301 catcaagcac cgaatctagc aggatatact gacaaggctg ctccacctga tcaagcgata
    12361 ggctaagccg ctttgatggt gcgctggagc tgctgcggta gtccaagaca agcctaagtg
    12421 aggctagggg cttctttagt cctgtcaaac taatagcgcc tatggcctgt acagtatcgt
    12481 attggtagcg atagctaagc tgagtatcac tctgacacag tagcttcttt ttagcaacta
    12541 agctaagctc ttgattaatc ctcagccctt ttgtatcggg cttaagaata gcctcaagct
    12601 tcaagctctg gccaaagcaa gaggtctgcc cactaaccct tgactcctca gtaaagactg
    12661 gagctgccag ctgccaatca ataggaaagg ccttggttaa taggtggcca gcagctgttt
    12721 taggctgtag ccagcttggc aaaaagatat ccttaccctt tatcagtctt tgtgtcagag
    12781 gctgaaaggt caatggctct gtaaataccg tagcatagct aaacatcatc acaggcctat
    12841 cagacaagca gtgactttgg catgatacat agtaatcagc agcaggtgcg aagtcatcag
    12901 aaccttggct gattggtctt ggatctgcct tgagctgcct ttttgtcttg tcagtgataa
    12961 agctgtattt gtcaagccga taagctaaga gcttctcttt gatagctgct tcagcgacag
    13021 tcagctgata gcttgcttct tgtaggcctt gggctctggc ggttaccttg agctgacctg
    13081 cccgaccatc aagggcaata atcgctagta gcctgccgcc ataagcctgc cgcgacaagc
    13141 tgctataagg ctgatggtca cgagggtcac cattatccaa ggctaagcac attccaggac
    13201 cctcaacttc aatgttgata aggagattag cattagctac cagggtctga tgggcatcta
    13261 atagggataa gtcaagataa agcaggctag gctctgcaag cagtttagga ggctcaaagc
    13321 aagaccagaa aagctgagca ggctgctggt agctgctcac acaggaacga ccgctggtct
    13381 gtgtgatcac ctgtcccttg tcgtcataag caatagctct caagctgcct gagcgataag
    13441 gaagcttcca tgtcaggtaa aggttttgat gaggggattc tgctgcgtca tcaccctcat
    13501 atagctggta gcaatggcct gctggcgttt catgccttgt cagagccttg atgccataat
    13561 caatctggcc cccatgacca tcatcaaaaa gtattctcac actagcagca ttactataaa
    13621 ccacaacctc caccatgccc tgatcatcta gctgaaggtc tttttcctgc cagctgggca
    13681 ggatatgaag tgtcgttttg tcttttgacc attggctttg gtagaaataa tagctatcct
    13741 tagcaaatcc agcagtatct aaaataccaa agtaggattg cttgggcgac ggccactgat
    13801 cagctgcgcc tgagtcaatc ttgttccaag gagtaggctc ccctagataa tcaaagcccg
    13861 tccaaacaca ctcacctgca acaaaatccc ttgtgattgt atcataccaa gcctcactag
    13921 ctaaggctcc ccagtcaacc gttgactggt cataggaggt tagctcatga tcctgactag
    13981 ctcctccctt gagatgatag acccctctac tattaatagc agaggctgtc tctgagccat
    14041 aaagcagcca agtcgggttg tccctatgca atcgatcata atctctggcc ttagcatagt
    14101 taagtccaat cactccttgc acggactgga gctgattgac ctgctctgcc aacgcttttg
    14161 tttcctgtgc ccagtgaaaa tgctggtcct tgagcttatt atctccaaag gtaataggtc
    14221 ttgactgatc cagctcaatg atccactggc atagctcctt agcaacataa gggtagtggc
    14281 tcacatcagc tgagaagcct tctaacaatt cattgccgat tgaccacatc aaaacagctg
    14341 gatcatgaag gcctgataga accatggcct gtatgctgta ttgagcccag gtggtttctg
    14401 ctgtagtgac tccctttagc ctggctgcat tttggtgtcc cactgtcttg tgaaaatggc
    14461 tcgaaaaatc atggctatta ccatttttag cataggtcca ggtatcaaag gcttcctcaa
    14521 tgagaaataa cccaagtctg ttagccagat ccttaagcct tctagcactg ggattatgtg
    14581 tgacacgcac cgtatttgct cccatttcct ttagtaaaac aagctgtcta gctatagctt
    14641 cctcataggc acaggcccca aggctacctt gatcatgatg aagacagaca ccctgcagct
    14701 taaaggcttt gccattcaaa aaaaagccac actcagcatc aaaatgtagc tgccgaaagc
    14761 ctgtttcaag tgtcagccga tcaagcactg ctcccttatg gtaaagaagc atatcaagct
    14821 gatagagctg gggctgagct ggcgaccaca gtttgatatg cctaagagga atggtcatca
    14881 ccagcctacc tgactcctcc aagaggccca aggctaccgg tttactctca tatactgtct
    14941 gcccttgctg ggtatctgcc agctgctcag atagactaag gctaagctga tagtcactca
    15001 aggggacctg ttggctgagt ccaagctcta tctcaagcgc tgcctgggat aaggataaac
    15061 gaagccgatc cttatcaaga tgaaccttag gaagaacggt caaaaaagcc tcccgataaa
    15121 gcccgcttcc agaataccaa cgcgagctag gcacctgatg ttcaacccga actgctaata
    15181 gattctcttg cccagggatt acaaaggctg agagatcata gctaaaggcc tgatagccat
    15241 tgacatgctc tcctatcaaa tgaccattaa ggtatacctg tgtttccata taagccccat
    15301 caaaggtcac ataaacctta tggtcagcca gctttggatc aagggcaaaa tacttccggt
    15361 accagcctac accacctagc ttataggcac tttgagcttc gccattaatc gtatagggct
    15421 gattaatgct aaaatcatga ggtaaagcta tctgctgcca gtccgaatcg tcaaaaagtg
    15481 gctcctgagc gagctgcaaa tcagccatca gaaagcgcca cccctttgaa aaggcatggc
    15541 agcgccctgc tttatcaatc cagtgaagct gataggtatc cccatgagat tgatccattg
    15601 gaccagtgat tgcatctaaa gacatcgctt tccctttctt aatagcttcc ctttatggct
    15661 tgataattat ccttataacg gtctctaaac tccttgggcg ataaaccatt taattttttg
    15721 aacattttta tgaaataatg gttggtatta tagcctgtct cataggcaat ttcgttaatc
    15781 gatttattgg tgtaaagcag caattgctgt gccttttgga tcctcacctg attgaggtat
    15841 tgggaaaaac tacactctgt ttcattttta aagcattgtc ccaaataaac cccattgata
    15901 tgcaagcgat ctgacacagc cttgagggtt aattcctgag agtattcctc ctgaatacag
    15961 gtaatggctt cactgaccag atcagaatag cgcttttggg gctgattgct tttgcttgtc
    16021 agctcaagca ccttttttaa ggctgataag atctgatcaa tggactgact atcatgaata
    16081 gtcttgacca tcgataggta ggtcattcga tctaaaatcg gaaattgacg gtaaatatct
    16141 gaaaacaaga gaaaagagac atgcttgaca tcttcaggag agaagcttag ctctgtcatt
    16201 tcctcaaaga ttgcctgtaa tttggagaca atggttggct cgtctccaat catcaaggcc
    16261 ttgttaaagg aaaaaaactg caatcgcgat tctggcagct caattttagc gttggtctta
    16321 gcagctacct gagacacctc gctgttgtaa aaaaggctcc ttctgacctg attatagctt
    16381 tcatacacat tttcccaatc aacaaccgtt tctcctagaa tgatctggtt gatggtattg
    16441 taaaatcgct cctgaagcgt attagtaaag cgcttagcct gatggctctg tcctaatagg
    16501 attactagat agaccttctt ttgctctgcc ttttttaggt aaaagggctg cttggaggcc
    16561 tcaaaaaagg cttctaaggc agggctaaaa gccttgcaat ccacatacaa caccgtaaag
    16621 cctaaaagct cagtctcggg ttgctcctgc gttagttgaa aaaactcttt ctcactcaat
    16681 tcatcagcaa gccagagatt gatcaagccc tcacgataag cagcctgacg caaagaagct
    16741 gccctttgct catcaagcca ttccttaaaa tagagcattt tagctaccag ctctttttta
    16801 tcaactggct ttaagaggta gcccttagtt tctagttcca tcgccctttg cacataggaa
    16861 aattcctgat agcctgataa aatcaaggtt tgcaaatgcg gcaatacatt tcttgctgcc
    16921 tcaatcaatt ccaggcctgt cataccaggc atattgacat ctgaaatcat gacatctaca
    16981 gcgcagtcat ctaggtaagc taaggcttct ttggctgacc ttgcagttgc cacaacctca
    17041 aagccaagcg cctgccagtc aacaatcacc tttaggccct gtaaaatcat gtattcgtca
    17101 tcaactaata agaccttgta cattaagctt cctttctaat tctgatttga atcctaaagc
    17161 cgccagtcgg tgcctgagac atggaccaag tcaccctgtc tcgatattgg tgaaataggc
    17221 gcatgtaaac attttgcagg ccaatagagc tattacccgt tgcttgaggg acctgtaagc
    17281 cctcctcaat agtcattaag cgttcagagc taatgccctt gccattatca agcacctgaa
    17341 ttaaaatgct gtctccctca tctagcgcct tgatgctaag ggcgttatcg tagcggctgt
    17401 aatcaatccc atgcacaaaa taattttcca ccaagggctg aatgataaac ttaggcattt
    17461 ccacatcagc cacgacagga tcaagcttga catgataggc aaagctatct ggatagcgca
    17521 tttgatacag gtagatgtac ttttcacaaa aggccagttc ttcttttaga gtagttacct
    17581 tatcctgact gatgttattt cgaagtaaag aggcaaaggc ataaatcaca tctgccaatt
    17641 cctcctgctg acagctaagc gcgtacatgc gaatatattc tagggtgtta tacaaaaaat
    17701 gagggttaat ttgtgattgc aaggcacgca tttgggcatc tctttgctca acctcaagga
    17761 catagatttc ttggatatag gcattgatat tgccaagcat ttgattgatc gcctcagaaa
    17821 tgtgatacag ctctaattcc atatgactgt tgtcaatcct taacgacaaa tctccagctg
    17881 caaccatttc aatagtatct gtaatgtcag agacctgctt gatataattg cgaaacaccc
    17941 taaaaaggag ctgcagcaat agccaagcta gcagtaaaga gccaagccca tacaggagca
    18001 ttgtacgcac agcctcttcc ataaaataag accttttgac cgccacatag gccagcaagt
    18061 ctcccgagcg attgtactga atatgatagc tcttgctgag agctgtcaaa tcaatagcct
    18121 gatccgcctt tagcgccttt ttaagacctg cttcaagctc cggaaaggca gcgcctccct
    18181 gatgaaagag ctctctgcca tagtaatcaa aggcaaaggt cgctaagtat ttatgctgct
    18241 caggctgtaa tatcgtacct ggatctgtaa aatgcaaata gagctgtcct gtgacgtcac
    18301 ccgactcagg gtggcgaatg gaccttacta agtaattgcc ctttagcgtc tgaggcttac
    18361 caaataagag ccggccggtc ttaatcgacc tatcagcata caaataagct gtgctatcgt
    18421 ccagcatcag ggtcagcccg tccaagtctg gatacaaatc aaaaagcctt ctgacctgct
    18481 ctgaaaacag aggggtattt ttgccctcgc cccaatcctc aaagaccttg gtaaaatatt
    18541 ggtttggtgt taaaagcatg tactgataga gattatgata atcctctgga cgtcctacta
    18601 actgctccag cacacgcagg gtaatatagt tttgggactg tagctttgtt aaggtctcat
    18661 ctagccgcat ttgcatttga ttatcgacca tttgataggt atttcgaatc gaataggtgc
    18721 ttaggccaat agcacttaag ctaaagagag ccactataaa caggctatag agcttcatca
    18781 agcgattgat taaaaagccc tgcttgagat gctctatcac aaaccgcttc aaggatttat
    18841 tggtcatcaa tgactccatc tatcatataa cgattgggct tggtagctat atccagcaaa
    18901 acaaccagag caccaaagct aagaaaaagg tacaggccct tatactgcca ggtaaaccaa
    18961 gcaactccag ctaaaaccat aagggtcaac aaaaactgct tggcattcaa gaaaatactg
    19021 ataaaagaca gcttgagatt ctcccaaaaa gcaatctcat aggtcactgc ataaaaggtc
    19081 atgtaaatca caatcatcac cagccagacc atgacaaaca tgataataaa ggataggcta
    19141 aaccacagca gcgattgaaa ttgaatggcc aagtacaggc tcgtattcag caataatagc
    19201 aataatccaa agaagaaaaa gctgagattg gcctctttga agacccgacg ccatatctga
    19261 aaggcccgct tgagcgaata atgtttctcc tgctgactgg tctccaaaaa caaggtaaca
    19321 atggtctgcc aagctggccc cactccaaaa atcacagctc cacataagga aagcaaatga
    19381 aatataaggg ttagctgcat cattttccag atgagaaagc atgctttttc aattcctgtc
    19441 ataagattat ccttttctag tatcctttgt agaaccagta gcgccctaag agaagcaacg
    19501 atccctcagc tagatggcta agatcttagc tgtcatgatg ataagatgag atacttttaa
    19561 tatagcatat tttactctaa ttgtgataaa agcttaataa aaagaggaca gccgactaag
    19621 gctggtaaaa ccttgtcagc aagggctttg gtggaccaac tgccttgcaa gcaggctctg
    19681 gcttttttct aagagaggcc ttatctgtca gctcttgtat gcctgcttga gctaaaaaga
    19741 actgaggctg tccccagttc ttaccacctt gcaaggaaag tccattgcct tatttatttt
    19801 tggtaacaaa gtcgtccaat tgcttttgca cttccttttg aaccttgtcc caaccagcgt
    19861 ccttaaggtc tgaaagaagt tttggaagag cttcatcagg gtctactgta ccagtattga
    19921 tactagcttt ataacggttc atcacgtttg agatatttga tagctccgtt ttgattgcct
    19981 tggtatctac cgtaaagcct aggatcggag attctttagc gtctttgatt gattggtcac
    20041 gcttggcaat catatcatct gtgatggatt cctgagtgta gaggatcttg ttgttaccag
    20101 tattccaagc acccatgtgc attttgggtt ggtagccatc aagcagcttg attttcttgt
    20161 cgccaacctt ttcccaggcc ttgccttcaa caccataaac aagaccattt agcaattctg
    20221 ggtcgctgtt aagaagggaa agaacttcaa cggccttttc tttattttta gacacatttg
    20281 acacgacaaa gttagccatt tgggcttgtg aggtcgtttt aagaggcttt gtcaatggtc
    20341 gtgacacaat gtctttacca gcagcattgg tcaagatggt atcgccatag tccataggac
    20401 cttgggtttc ttcacgcatg aaccaggtat tgccttcaag cgggtagcct tctgtgttgg
    20461 ttgctgcatc tgttggaatc aagccttcct tgtaccattt atgcatcaag cgtaggtttg
    20521 ctttaaaggg ctcgtcttcg tactgattaa tgatggttgg tttgccttca tcgattttaa
    20581 cagcaaatgg ttgatttttg gtcaatgggt aatcgtagtc acctgacatg ctaaagactt
    20641 gaccaatcgc aaaggcagcg gtatttggtt ctttttcgtg gaattgcttt aggactgctt
    20701 cagcatctgc ataggagttg atgtttgaaa tgtcaaggcc atatttgtct accaattctt
    20761 tgttgaaaga cagcatttgc tgagcataga cgttagcatc tactggaaag gcataaagct
    20821 taccgtcaat ggtatttcct ttaatgtagg ccggatctag gttcttatag gttttcttgg
    20881 cgtattttgg cattagcttg gtcaaatcag caaaggcacc cttttgagca ttgaccacat
    20941 aattgttggc aaaggcaatg tcgtaatttt cacctgacgc aataatggta ctcatcttgt
    21001 cgtcccaatc accccagcca atgtattgca aatcaaccgt tgctcctgtt ttttccttaa
    21061 tacgtttatt tgcaattgtc atcagctcat caaagttatc aggcttatct cccacctgat
    21121 acatcaatag cttcacctca ccgtccttag aagctgattt gcttccacag gctgtcaagc
    21181 tagcagctgc aagcacagct cccgtcacac ataagattgt ttgccacttt ttcatcagta
    21241 agcctcctaa aataatttct ttttttgata acagaatcat tggaacggtc agctgtatga
    21301 cctattccaa atgggtgatt attccttaac cccgccaatg gttagtcctc caacaaagta
    21361 tttttgaaag aaaggatagg ttagggcgat cggcaaagtt gcaatgacaa caatagccat
    21421 gcggacagat tcctttggta aagaggctaa gctatcagat agctgggcac tcataccagc
    21481 attttgggct agtgcctgta tattgctttg aatcttcatc aagaggtatt gcatcgggta
    21541 gagactctcg ctttgcacgt aaagcaacgc attgaaccaa tcattccaat aggtcaaggc
    21601 tgagaacagg ctaatcgttg caatcccagg aactgccaaa ggtaaaacga ttttcataaa
    21661 aatcatcaat tcacctgcgc cgtccatacg agcggattca ataatactat caggaacagt
    21721 ctttttaaag aaggtcctca tcaccaaaat gccaaagggt cccaaagcca taggcaaaat
    21781 caaggcccaa atcgtatcct ttaattgcag caggttactc accaccaaat aattggctac
    21841 catacccggt gcaaaaagca tggtgatcaa ggcatagatg gtaaaaaaac gcctgtaggg
    21901 aaaataaggt cttgagatgg cataagcata ggttgaggtc attgtggtat tgataaaggt
    21961 tcctaaaacg gtgataaata cagacaccgc aaacgatctt atgatccgat gagacatagc
    22021 cccttggaaa atataatgat aagcctttgt cgaccaagca gctgggaaaa agctatagcc
    22081 atgattgatc agatagcttt catctgtgaa ggaaataatc atcacaaaga taaaaggaat
    22141 gatacaagaa atggcaaaaa aggcgattaa cacattaaaa acaacattgg ttttttgatc
    22201 aaaggttctg acattaacct ttttaacagt tttctttttc tccatgtcct cctcctaaaa
    22261 taaggctgca tcgggatcca tacgacgaac aaaagcattg gtgatgagca ggatacaggt
    22321 tccgaccaca gattgataaa gactggccgc agaagccata ctaatatcac cagtagctgt
    22381 cagggcattg tagacatagg tatctaaaac actggtaaca tcgtaaagag gacctgaatt
    22441 tttaggaatc acataaaaca agccaaagtc agatttgaag atactcccaa tattaataat
    22501 caataggata gacatcatcg gcaaaagctg tggaatggtg atatgtctaa tttgctgcca
    22561 cttactggca ccatcaacca tagccgcctc ataataagta tcagaaatgc ccttaaccga
    22621 tgcataataa atgatactat tgtagccaag ccccttccaa acactcataa aaagcaaaat
    22681 caagggccac caggttggat tggaatacca tttgattggg ctattgccgc tatcaatgag
    22741 cagctgatta ataaagccct tatccgtatt taaaaaggca gaaacaaaat actcaatcac
    22801 aacccatgat aagaaataag gcagtaagga catggtatga tagaccttaa cagccttctt
    22861 gtttcgaagc tcactcatga taatggcaaa ggcgatggca aaaaagacat taaatagtaa
    22921 aaaaataaga ttataagcaa tggtatttcg cgtaatcaac caagcatcct tagaggcaaa
    22981 aaggtattta aagttatcta agccaaccca gggactttct ttcaggcttt ccataaagcc
    23041 tcctgctgag taatgaaaat ccttaaaagc caccacatta gctaatactg gaatataaaa
    23101 gaaaaagatg aaccagacaa atcccggtaa taccatcagc aacaaagcgc ggtatttgat
    23161 cacatttttc caaaaggatt tcttgctgct ggtctttgtc gtcatctagc caacctccct
    23221 ttgcttttca attgatgctt caagtatatc aagcgcttac acatagaaca agcaacaaat
    23281 tataggtttg ataacacaaa ttataggttt gataacacaa attataggta tcatagcaca
    23341 aaatatagga atgctgagaa agccttttca agcccttcaa aatctgtcat actaagggta
    23401 gctaattggt aatatacctg ttataggagg aattacaatg accttattat gtatcgacat
    23461 aggcggcacc agcatcaaat ttgctatttg tcacaagggc aggctaaaaa agcaaagcag
    23521 tcgcccaact ccccaaagcc tagaggactt ttaccatatg cttgacgagc gactggctta
    23581 ctaccgcaca gaaaagctct caggaattgc cattagctct ccaggagctg tcaataaagc
    23641 aacaggcatc atcgagggag caagtgcact gccttatatt catggctttc cgattcagca
    23701 atgccttgag gagcgactag gtctgccggt ttcgattgaa aatgatgcca actgtgctgc
    23761 tcttgccgaa tctgctctag gtgcaggaca aggcactagc agccttgcca tgctggtact
    23821 tggcaccggc gttggaggca gtctagtgat taatggcagg attcattacg gtgcccattt
    23881 atttgggggt gagtttggct ttatggtcat gaatgagcgc tatcaaacct tcagcgagct
    23941 aggcactgtg gtcaatatgg ccaagcgcta tagtcaagcc gtaaatgatg gcaaaagcta
    24001 caccggtaag gaagtgcttg aactagctga ccaaggagat cctgtggctc taaaggaaaa
    24061 gcaggtcttt ctgcaaagtc tggcaatggg ggtgtttaat atccagcatg cctttgatcc
    24121 tgaaatgatc ctaattggtg gcggtgtctc tcaggctgac tttcttcttc ctgcccttga
    24181 ggctgagctg gataagctct atcagatagt cagcatttct gatttgagac cgcagcttgc
    24241 tatctgccac tttaaaaacg aggccaacct actaggtgcc tctattgatt ttatgcaaga
    24301 gcatagaaag gacgagatgt ggatcgatta gacttcattg acacccgctt tggaacaacc
    24361 aatcactacc atttttcaca gggaaattgc ctgccattga caggggttcc ctttggcatg
    24421 cattatctaa gcgtcgaaac cagtcaagat cgaggggctt ggtggtttca ccccgatgat
    24481 cacagctttt caggtattcg cttgacacat caacccagcc cttgggtcgg tgattttgcg
    24541 acggttactt ttcttccagt cagcggaccg ctgaccaagg gagatgtgtt tcataatcag
    24601 acctcctatc gtcccaagga ggcagctttt cggcctcatc ttcttgagat ttttagccag
    24661 aggcaccgga ttttgacacg agcaacagca gctgcctaca gctttcattg tgatttttcc
    24721 tttgataatg gcaaagcagg cttgattatc cataaccccg gaaaaagctc ctggcaggta
    24781 acagctgatg gcaaaacagt ccttggctgc gtgcaaaaca tcacagactg tcgggataaa
    24841 gacctaacca tgtttgttta tctccagttt agcagccctg ttctaaaaaa gcttatcgga
    24901 gaagacttaa actccaaatc tcttgatgat tgcagcaaga cgtcctttac ctatctccaa
    24961 tttgctgatg acctcaaaca tcttgagctt agggctgctg cttcttttat tagctttgat
    25021 caagctcagc tcaattggca gagggatttt cccagatcat ttgaaaaaag ccttgaacac
    25081 agccgcaaag agtggctcag ctacctcaat cgtattgata ttaaggataa ggactttgac
    25141 aaggtcaaga cctattacca gcatttttac cgagccctgc tatttcccca aaggtggtat
    25201 gaaatcactc cagccgggca ggcgattcac tataatacaa caagtcaaag acctgttgct
    25261 ggaaaatact ataccaacaa tggcttttgg gatacttata aatctgtcta tcctttgctg
    25321 tctttgattg cacctgagat ttatgctgat attttagagg gactcttatc agcctatcag
    25381 gataccaact atctgccaaa atggctgtct ccagatgagc gaggcctgat gcctggaacc
    25441 ttggttgatg ctgttattgc tgatggagct gtcaaaggca tcagaaaaga cctgatgcct
    25501 gagcttttag aggccatgct ggcaactgcc aatacagaca gtcaaggaac aggctatggc
    25561 cgcaagggca atcaagacta tcaagagcta ggctatctgc caaatagcta ccaggaaagc
    25621 gtcaatcaga ctcaagatta tgcttatagt gatttttgta tcggccaggt agctgccacc
    25681 ttaggcaaga tccaattaag cagccaatac cacacgcgat cactcaatta ccgccatttg
    25741 gtcgatactg ataccggcta cctcaaaagc aaggatcgac aagggcaatg gcaatgtggc
    25801 tttaacccta tccactgggg gcaggactac accgagggct cttactatca aaatggattt
    25861 gccttttatc atgatattct aggctacatt cgactgatcg gaggaaaggc cgcctttgcc
    25921 aaaagacttg aggagctgtg taatcatgag cctgtgtttg acgttcacag ctatggcttt
    25981 gaaatccacg aaatgagtga gctagccgca caggattttg gtcagattgc tatctcaaat
    26041 cagccaagct ttcacctccc ctatctctat cactatatcg gtcagccaca atacagtcag
    26101 ctaatcctta aaaatctgct cagccatgcc tttaccgata caggctaccc aggagatgag
    26161 gacaatggca gtatgagcgc gtggtatctg ttaaatagcc ttggtcttta ccctgtcaca
    26221 ccaggaactg ggcaatacct gattggtatt ccaactgtag atcaggcaac cctttatctg
    26281 ccaaacggca atactatcca aatcagctgc cagggtaatg tccctcaata ccaatttgtc
    26341 aaagagctca agctcaatca ggccagctac aacaagctct acatcaatca tgatgatctg
    26401 attcagggct gtcagctcga ctttcatctg ggcttggcgc ctccgctcaa agactatttg
    26461 gccgaggatc tgccctattc cctaacccgt taatagctaa aaaagcatgt catagcttgc
    26521 tgtaagacaa gtcatgacat gcttttagct atgtgacttt agtccgtttc gctccgtagg
    26581 tacgaaacaa taaatcaccc gttaaacgga tagctatgat gttaggaaat cctcttttac
    26641 actcctttat cgccatcact ggtatagctc atcagcaagc ccttatgcta accaatcacc
    26701 ctaacaggta aaaccgctaa agctactagc tgctcctgta aaatctctct tagcttctct
    26761 aaacctagct ttaaaggaga ttgggctggc ttttgtgttt tttcttcttt tcttagctaa
    26821 ttccatttgc ctctgccacc tccttaaacc aataccctga ttttttaaca cgccgacgct
    26881 gagtgcggtg attattttcc accagaccat aacggttttt ataggcattt agccaagacc
    26941 agcaatcaat aggtgtccaa acatgatagc caaagcaatt agagcctgct tgaatgccct
    27001 tatgaagata ggtcaggtgt tcttttaaaa attgaatgcg atagtcgtcc tgaatctgtc
    27061 cgctctcatc tcggtaacga tcctctccag aaacaccaac cccattttca gataaaaacc
    27121 aagggatatt cctatactga tcacgcattt ttagagcaat atcatagacc gcctctggat
    27181 aaatctccca gcccttgtcc acattcatac gacgctgcgg catcagatag gcatcataat
    27241 accactcagg actccaggaa gggctaatca caggaataac ctctggcgcc ttcacgcgct
    27301 taggatggta aaaattaatg cccacgtaat caaccgtata agcagccata agatccagct
    27361 cctctggtgt ggactgccag agcactccat ctcttttcag catcgctacc aattcccctg
    27421 gaaagctacc gcaaacagca gccgacatga acaggtcatt gtgccacagc tctgcaacat
    27481 gagcagcagc aagggcagcc tccgaatcag ttgccggata gatcggtgtc agattgagaa
    27541 tggtaccaac actgccattg ctcagctctg ctgcttgttc tcgataagca cagataacct
    27601 tagccgttgc aagtgctagg ttataagcca cctgtaccgc ttttttccca tcaacaatag
    27661 ctgggtagtg gaattgcagc aggtatgagc cctccacaac aaccataggc tcattgtgta
    27721 caaaccaatc cttaacccga tcaccaaact gctcaaagca tactctagca aaggcaacaa
    27781 acaaatccac aacatgcttt gattcccaac cgccatattt ctgataaaga gcaattggca
    27841 aatcaaagtg gtgcaaattg atcaccggac gcataccatg tgccaggcag gcatcaatca
    27901 ccctgttata gtaagccagt ccatcgggat tgatcgtggc tgtctcaaaa tcatcaatca
    27961 agcgtgtcca ctggatagag gtccgatagg aattgtgccc caaagacgct aataaagcta
    28021 ggtcttgatc atactgatga aaaaaatcag aggccgtatc aggcccaaca taatcataaa
    28081 aaagctcagg cctttgctca taccaataat caaataaatg acggtgtggc ttttgaaagc
    28141 ggccttcgct ttgagggcct gatgtagcac ctccccacca aaatccttct ggaaactcta
    28201 gcatgtccct tgttctccct tataaactaa ttaagtataa tcctcagttc tagcttcagc
    28261 gacctgtacc tgattgccta gcatgctatt ctcctgaaga taatgcagct gataaaagcg
    28321 gcttggaatg ttgcttccaa ttcgatgctt ttgctcttgc aagtcggcat attgctgctc
    28381 aagatcaggc gcttgctcta aaataaccct ccaaaagctc tgatcagcct tagcccgatc
    28441 aaaccaaggt gcaatagcct gttgaaactc aggaatatca agctttttca gcttatccac
    28501 cagctctact acctcagcta cccaagcaga taagctcgct atgtccttac gcacaagggc
    28561 ctcctccacc tcaaagggga ggtctctgtg caaatgacga ttgccattat gccaagcaaa
    28621 gcgcaaaagc gctaaagcca ttgcctcatc tccagtataa tctctcaagg cctctagcca
    28681 agaatagctt ggctgataac gcttggcgtc ccacaggtag cgactcatat caattaaagt
    28741 cggctttgat agttcccagc taatcattgg attagacaca atccccctga cctgatagtc
    28801 tggctgacac aagaaaggag agcgattggc aaacggggtc aaaaagagcc tcttagaatc
    28861 gtcctgataa tcattgacag ggatattatc ccagatgatt atgggccgcc ggtagatggc
    28921 tgctattgtc tcaatatctg cctgagaaat ctgactggcc agagtgcttg ggccagtcca
    28981 gaaaaaagcc acctcagcag gaatagcctc tgataactct gctaaataaa gggagtcatg
    29041 atgattatca tactccgtcg gacagacaac cagatcagga gctgcatgct gccgctgtaa
    29101 aaactggtaa acagctgttg ccaaatgtgc ttgggcatag gctgtttttt tgaaacgtct
    29161 ctcaactgcg tccacaatgt ggtagtcaat atcatcaagc agcagaccaa aatgacaaac
    29221 acccaaatcc aacaattgct gcaatttttg atagagcagc tgatagtcct ctttcttggt
    29281 gtagtcaaaa tcaagccccg gactaatcat gtaccaaaag tcaacctgtc tttccttggc
    29341 aagctggatc agatccttaa aatgagctac ccagtcctct ggatagggct cacgccaatg
    29401 gctacgctga taatcatcat ttttaggcgc atacatgtag gtattcatgc ccttatcagc
    29461 aataaagctc aaacaatcta aacgctcctc acgcgtccaa ggggtgccat aaaagccttc
    29521 aatcacacca cgcatagcaa aggacggact atgcctaacc gaaacaatcg gcaaataaag
    29581 cctgccctct ttaacagtca tgaccttttc taaagcctcc tgagcatagc gaaagcctct
    29641 taaattttgg ctttcaatca caagctcctt atcctctgaa atggtcaagg taaaggcatc
    29701 cctagctaag gtgcggttaa aaacgtgctt aagggtcaag tcagctgctc cctcctcaac
    29761 ccagttgaca tagactgacg ctgcaagact aggcttcata gctgtttggt tctcaaatcg
    29821 gaaaaaacga ccaacaaagc gacaggaaac aggggcgtca aaaacgaggt aatcacctct
    29881 ggttatcacc tcctgatagt ccttgagggc ttgataaata gacatgacac ttctcctttt
    29941 tatagcattt ctagggactt ttgactgctt tctctgataa agaccttaac aggaagctga
    30001 caagacgccg tctgctgatc agaccgagtc agctgctcta tcaatagctg cgctgcttgc
    30061 tgtcccatct ggtaaaaatc ctgagcagct gttgtcaatt gagggctgat taactgagag
    30121 gcttggctgt tgtcaaagcc aacaacagct acctgatcag gaatagatag cccgacctgt
    30181 agaatttttt ggatcaattg aatggctagc caatcatttt cgaccactaa gccagtcttt
    30241 tcagatgtag cagccgtcag ctcatcaacc aatcgctcaa gataagcagc attgctttct
    30301 gacttcagct tcacaaaata attggcctca agctctgttt ccgccatcgc agccaaataa
    30361 cccaaataac gatctctaac agaggaaacc tcaccaaagg aagcagttgc cacaaacatg
    30421 atccgacggc aatcctgatc aatcaaatgc ttggtcaact cataggctcc gcccttattg
    30481 tctgcaacaa ctgctggaaa gtcaaacagg tctaaggcct tatccaaaag caccagagca
    30541 agcccacgct gggcacaata aaagagcagc tcaatactat gattaacgtc ttctggataa
    30601 taaatcacac cagcataatc agctagctcc tccaagctta ccgtacttgt aagctggacc
    30661 atcaggcgat agcctttgtc agcaacgatc gtcatgattc ctttagcata gtctcccaat
    30721 tcgtaatcag aagcaaaggg caggatcaac aaaatgtcct tattaggctg agtagacggt
    30781 ggtgggccat cggtcacaaa gctgccctta cctctgctgc gtgtgatcaa gccctcttgc
    30841 tcaagctcta ctaaggctcg cttagaggta atgcgactaa ccgaaaattg ctctgatagg
    30901 gccttttctg ttggcaggcg gtcacctgcc tgtaactgcc ctgaatcaat ttgtcttttg
    30961 ataaaatgat atatcttttt atatagtaat tcagtcattt tttactcctt ctagcagtat
    31021 atcatgaaaa aaaagacttg taaacctttt ctaaagtggt agacaaaaat aaagttatat
    31081 cttataatta aaaaagatat taaatgatat atcttttagg aggatatgat atgacaagac
    31141 ctattcctag cagtgtgctc aggtttatgg ataccattga agagctctgc ggtgaggagc
    31201 accgcagctg ggccattaat tttaaagcca gcttcgccaa caccttagaa acgaccctaa
    31261 aaacctatga cgacggcacc agctttctcc taacaggtga tattcccgcc atgtggctgc
    31321 gtgattcaac cgcgcaacta aagccttatc tctttttagc caagacagat gctagcatga
    31381 gacaaattat agcaggtctc gttaaacgtc agttccgtta catttgcatt gacccctatg
    31441 ccaacgcctt taacgaggag gaaaatagca agggccacca agcagaccac acccagatgg
    31501 gaccttggat ttgggaacga aaatatgaga ttgattccct ctgctatccg atccagttag
    31561 cctatctgct ctaccgagag acaggctgta cagagcattt caatgaggat ttccacagag
    31621 gaatcaagct gatccttgat gtctggagca cagagcaaga ccacactgcc tctccttaca
    31681 gctttgagcg cgacacctgg cgcaaggagg ataccttgac ccacaacggt aagggagctc
    31741 ctgttgccta tacaggcatg acttggtctg gctttagacc aagcgatgat gcctgccaat
    31801 acggctacct cgtgccgtcc aacatgtttg ctgctgtcgt cttatcctat cttgaagggc
    31861 tctatactga tctctttaag gatcaaacga ttgctaggag agctcatgca cttaggcttg
    31921 ccattcaaaa agggattgag gagcatgctc ttgtaaccaa tagcaaaggc gaaaccattt
    31981 atgcctatga ggttgatggc atggggcatt atgctattat ggacgatgct aatattccaa
    32041 gcctccttgc ggcaccctat cttggctttt gtgccaagga cgaccctatt tacctagcca
    32101 ctcgtcaaac cattttaagc tcggaaaatc cttattatta ccaaggcagt gctgcttctg
    32161 gtattggttc ttctcatacc cctaaaaact atatttggca tatcgccctt gccctacagg
    32221 gcttaacagc gcttgatcaa aaggataaag caaacatgct tgatttactg gtggctactg
    32281 acgcgggcac ccacttgatg catgaaggct ttgacgtcaa tgatccgagt cactatacac
    32341 gtgaatggtt ctcatgggca aacatgatgt tttgtgagct tcttcttgat tatctgggct
    32401 ttaccattag cccttagaaa gtgagtcagt gatgacacct aaaaaagtac atatcatttc
    32461 acacagccat tgggatcgcg aatggtacat ggcttatgag cagcaccaca tgcgcttgat
    32521 ccagttaatt gacgatttac tagatctttt taaaacagac cctgattttc atagcttcca
    32581 tctagatggg caaaccatta tcctagatga ctatttgcag gtcaagcctg agcgtgaggc
    32641 cgatattaga caggctattc aggctggtaa gctgcggatc ggaccttttt atattctaca
    32701 ggacgccttt ttgaccagca gtgagtccaa tgtccgaaac atgctggttg gcaaagagga
    32761 ctgtgataaa tggggggcaa gcgttccact gggttatttt ccagacacct tcggaaatat
    32821 gggacaaaca ccacagctaa tgcgaaaagc agggctaaat gccgctgcct ttggacgtgg
    32881 tatcaggcct acaggcttta acaatcaagt ggatacaagc gaaaaataca gctcccaatt
    32941 ttctgaaatg atctggcagg gacctgatga tagccgcatt ctcggcttat tatttgccaa
    33001 ttggtacagc aatggcaacg aaatcccaac cgaggaaaaa agagcccgtc aattctggga
    33061 tcaaaagcta gcagacgctg agcgctttgc ttctaccagg cacctgctga tgatgaatgg
    33121 ggttgatcac cagcctgttc agcttgacgt taccaaggca attgcccttg caaataagct
    33181 ctatcctgac tacgaatttg tccactcctg ctttgaggac tatttggctg acttgagtca
    33241 ggagctgcct gaggagctat caactgtggc tggtgagatt accagtcaag aaacggacgg
    33301 ctggtatacc ttagccaaca ctgcctctgc tagaatttac ctcaagcagg ctaataccag
    33361 agtgtctcgt cagcttgaaa atgtcacaga gcctcttgcc acgatggcct ttgaggtcac
    33421 aggcacctat cctcacgagc agctgcgcta tgcttggaaa acattgatgc aaaaccaccc
    33481 tcatgactcc atttgtggct gcagtgtcga tagtgtccat caggagatga tgcctcgctt
    33541 tgacaaagcc tatgaggtgg gaacttacct ggcagagcgc tctgccaatc aaatagctga
    33601 ggctattgat acctccatgt ttccagagga tagctgtcct tttgtcctct ttaatacctg
    33661 tggtcatgag aaaaaaacgg tctcagacct cactctaaca tggaaagtct ttccatttgg
    33721 gcagcggctg cctaaagctg tttatcaaga agccaaggaa tacctagaga caagacagcc
    33781 gcaatttcag gctattgacg cagctggcag ggtcatagag gaggctgaaa tcttaggcac
    33841 agacatcacc tttgattatg ccctaccaga gcgcaccttc agagaagcct actttgctat
    33901 caaggtacag ctaaggctcc cgttgacgct ttctgccatg tcatggcaat gtcttgcact
    33961 aaaagagact gatcagcctt gccaagcagc tgacactgac aaaatgctct ttcatcagga
    34021 caggagctgc cttgaaaatg agttcctaaa agtcatcatt gcagcaaatg gcctgctaac
    34081 gatcgaagat aagctcaacg gcaatacctt tgacagttgc ctccaatacg aggactgcgg
    34141 agatattggt aacgaatata tttttcgcca gcccgatcat gatatcccct accttgctca
    34201 tcaagggagc tgtaagctgc gtgtcttgac caacacagcc catcttgctg aaattgaatt
    34261 gacacaaacc tttgatattc ccttagctgc agatgatcgt ctacaggctg aaatggaggc
    34321 tgtcattgac attagagagc gtcaggccaa acgctcacag gaaaaagcgc cctttacagt
    34381 aaaaacagtc attcgcatgg aaaaagaaag cccacgtcta caatttcaga ccagctttga
    34441 caatcaaatg acaaatcacc gcttgcgcgt cttattccca acccatttaa agacagacca
    34501 ccattttgca gatagtattt ttgaaacggt aaagcgtcct aatcatacca atgcccaatt
    34561 ctggaaaaac ccaagcaacc ctcaacatca agaagccttt gtcagccttt ttgatggcag
    34621 gactggtgtc actgtaggaa atgagggcct cagtgaatat gaaatcctac cagaaaccaa
    34681 tactattgct atcacgctac taagaagtgt cggtgagctt ggagattggg gctacttccc
    34741 aacccctgat gctcaatgcc tcggtcaaca gactgtcagc tttagctttg aaagcattaa
    34801 cgctaccaca cgctttgcca gctattggcg agctcaagag gctcagatac cagtcactat
    34861 ggcgcaaacc aagagccatt ctggtcagct gccggctcag tatgcttaca tcaaaggagc
    34921 aactgatcac gttgctctca cagccttcaa gcgtcgccta tccgataatg ccctaatcac
    34981 gcgcagctat aatgtatcaa atgatgaggc ctgcgccttt accctagcaa tcccagacca
    35041 cacagcaagg gtgaccagcc tactagaaga ggatcagcat gaacccctac cagctgagct
    35101 tggcaagggt gacatcctaa ccctagcttg gaaaaagagt gaatcagctc atctataatc
    35161 aaattgccac taccttgatc taaatcacaa gaaaaaagac tggggcaaaa agagctgcac
    35221 tttagaaagt cttaactaag atatattatt acttagtcta attaaaaagc aaacaggtct
    35281 agttttctga gattccgaaa actagtcctg ttcgtttatt ttatataggg ttagactttt
    35341 accctagcct ctttttagca ttatcaagct aatcgctata ggtctacagt ccagtctaaa
    35401 tgtctcagag cttgctattg tagatgacag atgtcgatga tatcatcaac gcggctaaac
    35461 acgtttgggt catgagtggc aaaaatcaga acggtatcag gactcaccaa actaagcaac
    35521 agctcaataa tctcatcacc tgtttcctta tccaaggcac ccgttggctc atctgccaaa
    35581 ataatgcaag ccttttttaa caataggcgt gcaatggcaa cacgctgagc ctgaccacct
    35641 gataattcat aaatgcactg tgagagaaaa ctactgtcta agccaacgct atgcaaggct
    35701 tccacaattt taggcttagg agctaatatt ttaagattat catagaccgt ttcttcctct
    35761 atcagtgcat agttttggaa aacatagccc aaatagcgct taaaataatc ttgctctttc
    35821 atgctccaga tttcctcacc atttaccaaa atctgaccgc tatctggctt ttcaaggcga
    35881 gcaatagcat ttaatagggt tgtcttgcct gatcctgaag gacctacaag tgcataagaa
    35941 cgattggtct caaaagtcaa gctaatcttg tcataaattg tcttttttcc ataatgtttg
    36001 gaaagctgtt ttatttcaat cataatatgt caaaatctcc tttgatgatt tgaatccgat
    36061 gcttcaaaat agcctgataa gcaaaaaagg acatacaaac gatttctcct aaataaagca
    36121 ggccaatgcc tagtaccatg agactatttc cagtaaggat tcccatcatt cctatggcaa
    36181 gaaacaaaca caaagctaag ggcaataaca atctaccaat caagacaagg cttttttgcc
    36241 ccatcaagga ccagacggaa atctttttgg ccttttgttt catcagagaa acaatgtatt
    36301 cataaatgat aaagcactgg gcaatggcaa ggaccgttaa ggcaataaca cttccgatga
    36361 gctggcttag gattttatgg cgttctaaaa tcaaatgatt ggaaacattg gtcagaccag
    36421 agacattcat caagcctgct tgtgttaatc gatcacgaat aagcgcctga cgatagatag
    36481 atttttgagc catttctcca aacttcgtca gtaatgatgg ctctgtcatg aatgaaaagt
    36541 ttaactgcac taatatagta tccacttctt cttgctgagc aaaaatgtct tgttggtctt
    36601 gcttatgatt aaacagaaag ctcttttgtc cgttaggaac ctcttgaaca accaattgat
    36661 tagcctttag gctgctatat tgaaaccatt cataattgac aatgtttaaa atgctgtcag
    36721 catctcccat catatgttta ggaatataaa tgactcctgc agcatcagct gctggccttc
    36781 cgtaatcatt gttaggaaaa atgtctttat tttttagcat aaatccctga ttgacataac
    36841 ggacttttga cgcaatcctt ggatcaaccc cattggtctt taactctttt ttgaagtcat
    36901 caggagctga ttgtaaattg gtttcgttaa ggcttgaagg ttctgaataa ataacctcac
    36961 tatccgaaaa agacaggaga aaatgttgat agcgctgatt ttcttccttg aaataatcac
    37021 tatcaatttg gtgattgtca tcagtatgag cactcagtgt ctctagccat gttatttccg
    37081 caaaatcctt agctgtatcc cattttccta gaacttgaat gtcattggca gatttaccta
    37141 tagtctccaa gcttttgtgt agagaaagcc cgaaaatgac gctagataaa caaatcccca
    37201 ccaaccagac aaagaggacc agaggggttg ctcgtttatt ttttagaatg gctagcgcct
    37261 tcaacgaacg gatattgatg aaaaataaag catgaacagc aagcatcagc aacaataaaa
    37321 tgacagcatt agtcaagatc agaagtgtaa atgacttgac aaaaacattg gagatactgc
    37381 cttgatagag aatgaagagg agaatactga ccgcaaagct agcccccatc agcaacaaat
    37441 cctgtagcaa ctccctacgg ctatagtgtt caaataagcc caggcttctt agtatcatag
    37501 actttttagc atacatcaat ttaacagcaa acaagaggag ggcaaacaca aaaaagaggg
    37561 tccaaatagc taaggatcgt aagtttgtga acaaaaaata ataaggcagg agataccaag
    37621 gtaaatcagc acctttgtag gtcaagccca gttcagtcat cgcggtttca aatgatgaag
    37681 gaagagacct cgtcgtgtag tacatgccac taagatcgtt tgtcaagagc tccttgcgat
    37741 tactgctata ggcagtcttt ttcccatttg tcccaaacag gtaggtagct tctttaccag
    37801 tatgatctaa gtagggacga taaatttgga tatgttcctg ctcggctaag gcttcgatcc
    37861 tgtctaaaac gtgtccctta tcaacatctt tgtttgaagc cactaatgaa aatgcagcct
    37921 gaacagggta tttgatatca ttgccatact ccttgaccgc accaaatgat aaacatgtca
    37981 aaagcagaac gaaaatacag ataactgtag ctctccacct cataaaaacc tccttgagaa
    38041 aagtggactc agaggataat atcttcatcc actaaaacgt acaataaaac attaaacctg
    38101 ataccagcca taacatgact ttgcttgaac ccaattccac tgcttttttg caccggcaca
    38161 agcccaacca tcgttttgac tatctctact ttttacattt ccccaaaagt ctgtcacaga
    38221 agcactactt cctagcctaa taggaactcc aagaaaagca tttgagtaag atcagctagc
    38281 actggtcatt ccagatctcc aagtgtcctt acatcttagg taagggtgtc tagcttctac
    38341 accaaaatca gttatccaag tggctgacgt caaggtcata aatcatttta
//
LOCUS       DARYSY010000018        35615 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYSY010000018 DARYSY010000000
VERSION     DARYSY010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35615
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            249..635
                     /locus_tag="TVR04_000797"
     CDS             249..635
                     /locus_tag="TVR04_000797"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269501.1"
                     /translation="MTKAGAKYHIPATTFNAWFNYHALTTEELAFLQKNPHMFISYRK
                     KNDTVTSYNDLNKPWKYYDDYGTIHWVEGKSHSISDWYFDSRTGAVLSKKNGDMVVNE
                     YSRIYSYAVQGMIHLKSLKAHWQIKS"
     gene            708..1130
                     /locus_tag="TVR04_000798"
     CDS             708..1130
                     /locus_tag="TVR04_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269502.1"
                     /translation="MKKTTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGHSRETGSWGTTVIINGESRMSLSFDRLSGLKEISGSSYHPD
                     TFKLVEKSGIEELEPIMYRVRDIEKVSLKGIRIIHSAE"
     gene            1141..2430
                     /locus_tag="TVR04_000799"
     CDS             1141..2430
                     /locus_tag="TVR04_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269503.1"
                     /translation="MSITDSSYHELARQAYNIEPSKAKANNADLIINDRIIIDRKTKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLNVL
                     ASKKSMSSYHKLKKHWQSTGKGISGSEELFLDAAQGMVLGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKMSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            2412..2804
                     /locus_tag="TVR04_000800"
     CDS             2412..2804
                     /locus_tag="TVR04_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269504.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKAYQKREDSLSERRR
                     VLDDLINSEYQKMGAFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQREAELLDMRRAYANTNN"
     gene            2785..3078
                     /locus_tag="TVR04_000801"
     CDS             2785..3078
                     /locus_tag="TVR04_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269505.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPQYDRLR"
     gene            3463..4260
                     /locus_tag="TVR04_000802"
     CDS             3463..4260
                     /locus_tag="TVR04_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1269506.1"
                     /translation="MIKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDRLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKIHANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPERTIAFGDN
                     LNDYQMLSFAGRAIATENARSEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            4261..5088
                     /locus_tag="TVR04_000803"
     CDS             4261..5088
                     /locus_tag="TVR04_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1269507.1"
                     /translation="MTRVKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDIISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDRQLARLPKAIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLKWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            5088..6545
                     /gene="ftsY"
                     /locus_tag="TVR04_000804"
     CDS             5088..6545
                     /gene="ftsY"
                     /locus_tag="TVR04_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1269508.1"
                     /translation="MGLFERLFGKKDKAKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTYAHAVVADVVSRTDDISKQAELSDKAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQVETNAEYQVAAQAPAG
                     SANQTADKEPRQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATALTEELRYEAKLENAKKPEALKRLIIEKLVAIYEKDGLYNEAIH
                     YQQDLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAEKADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            6834..7673
                     /locus_tag="TVR04_000805"
     CDS             6834..7673
                     /locus_tag="TVR04_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1269509.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGVIISNPLRWEIQRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEASIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLVVKDKYPEEYHCVRQISHHMKKVYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            7678..9540
                     /locus_tag="TVR04_000806"
     CDS             7678..9540
                     /locus_tag="TVR04_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1269510.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSVIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVAAGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDAVK
                     QGQPLLRVDLEFIRSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            9567..10988
                     /locus_tag="TVR04_000807"
     CDS             9567..10988
                     /locus_tag="TVR04_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1269511.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTAGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKTYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(11173..11988)
                     /locus_tag="TVR04_000808"
     CDS             complement(11173..11988)
                     /locus_tag="TVR04_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1269512.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQIHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(11988..12890)
                     /locus_tag="TVR04_000809"
     CDS             complement(11988..12890)
                     /locus_tag="TVR04_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1269513.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLKKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESAQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFVSVSAVMITIYCLLVGVL"
     gene            complement(12931..13086)
                     /locus_tag="TVR04_000810"
     CDS             complement(12931..13086)
                     /locus_tag="TVR04_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269514.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     AKTVKQD"
     gene            13258..13980
                     /locus_tag="TVR04_000811"
     CDS             13258..13980
                     /locus_tag="TVR04_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269515.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            13964..15289
                     /locus_tag="TVR04_000812"
     CDS             13964..15289
                     /locus_tag="TVR04_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1269516.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLIVLCTGLVASF
                     YVLIMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFAVLEDLKRIDLVALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEVLVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRSFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            15448..16320
                     /locus_tag="TVR04_000813"
     CDS             15448..16320
                     /locus_tag="TVR04_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1269517.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKINGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVREKTADIGMVSRDLTAEESKGLTDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            16390..17253
                     /gene="pstC"
                     /locus_tag="TVR04_000814"
     CDS             16390..17253
                     /gene="pstC"
                     /locus_tag="TVR04_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1269518.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAVIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGLGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTTIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSTHD"
     gene            17246..18061
                     /gene="pstA"
                     /locus_tag="TVR04_000815"
     CDS             17246..18061
                     /gene="pstA"
                     /locus_tag="TVR04_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1269519.1"
                     /translation="MTNYLLKALVYLLALLTFGSLFLIIAFMLVKGLPNLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVFFLGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKVVLPAAIPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            18063..18815
                     /gene="pstB"
                     /locus_tag="TVR04_000816"
     CDS             18063..18815
                     /gene="pstB"
                     /locus_tag="TVR04_000816"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1269520.1"
                     /translation="MGAFSTKHLNVFYGDFQALKDISIDIPEKQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEILLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKSLDQLVEQSLRGAAIWDEVKDSLKKSALSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            18831..19496
                     /gene="phoU"
                     /locus_tag="TVR04_000817"
     CDS             18831..19496
                     /gene="phoU"
                     /locus_tag="TVR04_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1269521.1"
                     /translation="MREQFELELQQLEQQLLALGQAVLAATSKSLLALAARDHEMASR
                     MIEEDHTINQAQLDIELACARLLALQQPQATDLRFVLVVMSASSDLERMADHMVSLSR
                     AVLRLKATHQLSDHAIAEQVHALGQKAQQQLAQLLAVMSSHDTQKAIALAKEDKQIDD
                     QYKTLSRDMMSLMKDQTIAIYQGTEYLSMLRHIERFADDITSICERLVYLETGEIISL
                     TDT"
     gene            19728..20048
                     /locus_tag="TVR04_000818"
     CDS             19728..20048
                     /locus_tag="TVR04_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269522.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAASHSKHVIEHSINDTKSL
                     SAARWGSRLQILNLLTQYKEKLRGGGFYFYQRKFRAEVGKAKTPAQIEELYDKFREEL
                     EKLA"
     gene            20216..22348
                     /locus_tag="TVR04_000819"
     CDS             20216..22348
                     /locus_tag="TVR04_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1269523.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLALTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLKERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLEAKAEAFITEGFPEPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYEFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELPVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNMLDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHENGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRDAD"
     gene            22335..22772
                     /locus_tag="TVR04_000820"
     CDS             22335..22772
                     /locus_tag="TVR04_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1269524.1"
                     /translation="MTLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQHCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            22836..23108
                     /locus_tag="TVR04_000821"
     CDS             22836..23108
                     /locus_tag="TVR04_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1269525.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            23386..24318
                     /locus_tag="TVR04_000822"
     CDS             23386..24318
                     /locus_tag="TVR04_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1269526.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            24315..25094
                     /locus_tag="TVR04_000823"
     CDS             24315..25094
                     /locus_tag="TVR04_000823"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1269527.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGAIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGKAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYVSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            25116..25520
                     /locus_tag="TVR04_000824"
     CDS             25116..25520
                     /locus_tag="TVR04_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1269528.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIIVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            25517..25936
                     /locus_tag="TVR04_000825"
     CDS             25517..25936
                     /locus_tag="TVR04_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1269529.1"
                     /translation="MSNFLKTLVIGAASGAAAAYFLSTEKGKVLKACAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     TSEHDKADDVIIDLNEEDIIINYPEDDSEKEADSNKS"
     gene            complement(26068..26349)
                     /locus_tag="TVR04_000826"
     CDS             complement(26068..26349)
                     /locus_tag="TVR04_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1269530.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            26511..27437
                     /locus_tag="TVR04_000827"
     CDS             26511..27437
                     /locus_tag="TVR04_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1269531.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKTGKELTVACNALMHQDMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            27545..28831
                     /locus_tag="TVR04_000828"
     CDS             27545..28831
                     /locus_tag="TVR04_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1269532.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFAAIKDDLIDELWKVAQRELATGFYYHTPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(28927..29253)
                     /locus_tag="TVR04_000829"
     CDS             complement(28927..29253)
                     /locus_tag="TVR04_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269533.1"
                     /translation="MKSMMKQLQSALIGFIDNQPPKKAKASPVNLKANQIITTIKEAQ
                     VKEIPIHVIYQAKSFTGHIKKYDQLTGQLVLKNTNQNLTAIIFLADIDKASLVPHTRT
                     STKEKP"
     gene            29388..29600
                     /locus_tag="TVR04_000830"
     CDS             29388..29600
                     /locus_tag="TVR04_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1269534.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(30498..30638)
                     /locus_tag="TVR04_000831"
     CDS             complement(30498..30638)
                     /locus_tag="TVR04_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269535.1"
                     /translation="MKKEYISYLSAAIFTLYALISLKWIFFALGLILMIIGLADRFKS
                     KP"
     gene            complement(31048..32541)
                     /gene="lysS"
                     /locus_tag="TVR04_000832"
     CDS             complement(31048..32541)
                     /gene="lysS"
                     /locus_tag="TVR04_000832"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1269536.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDE
                     NYDIFKKADLGDFIGVEGDIMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFVTRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVAGVD
                     FWSEMTFEDAKALANEKHVPLEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            32883..34361
                     /locus_tag="TVR04_000833"
     CDS             32883..34361
                     /locus_tag="TVR04_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEL1269537.1"
                     /translation="METYDIHGKPYHRTLMIILLLVGTFAGVLNQTSLGTAIPTLMEN
                     FKVPLSTTQQATTWFLLANGIMIPVSAFLATRFSTKRLYMTAYAILVSGLLLAALAPT
                     AHWGVFLTARIVQACAVGITMPLMQVVMINVFPAEQRGAAMGINGLVVGLAPAVGPTL
                     SGWILKKDFSVLGIYLGWRAIFILPLVILLLVLSLSPFMLRDVIPQQAVKLDSTSLGL
                     SILGLGAFLWGFTNVAAYGWLDMVYVILPILVGIGGIYLFSKRQLQLEKPFLDIRVFR
                     NKQFTLTTIAIALTMMAMIGVEMMLPLYLQNVRDLSPLNSGMVLLPGALIMGLISPVS
                     GRIYDKIGARYLALLGFTILAAATLPFVFLNENTSRFLITVLYAIRMFGISMILMPLT
                     ASAMNALPSHESAHGTAANNTVRQISSSIVVAVLSSVTQNIISSKQPPKMLLSIHPEQ
                     YAKKLLEANLNGFHASFFLGFMFAVVGFIVVLFLHKGKVIEK"
     gene            34673..35578
                     /locus_tag="TVR04_000834"
     CDS             34673..35578
                     /locus_tag="TVR04_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1269538.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINQAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQTTGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVVLLRLNKQQERVLRMKYANR"
BASE COUNT        10109 a         6810 c         8372 g        10324 t
ORIGIN      
        1 cggttgttgc tgcgggaact gatccgaatg caaaggactt aaagctccgt atagctactg
       61 tatcacctgt aggaatggag cccatggcag caactgttac catatcataa gacttagttt
      121 ctgcaggtct tgcaaaatat actaacctat ctccacagta caagtcgtta gaagctttta
      181 tcgaaaccgt tcaagactta cctgatgtcc gtatttcaca gctaacaggc tatagccaag
      241 gggcttatgt gactaaagcg ggagcaaaat accatatacc agcaacaaca tttaatgctt
      301 ggtttaatta tcatgccctc accacagaag agttagcttt tttacaaaag aacccgcata
      361 tgttcatcag ctatagaaaa aagaatgata ctgtgacgtc ttataatgat ctcaataagc
      421 cttggaaata ctatgatgat tacggtacga tacattgggt agaaggaaaa agccatagta
      481 tctctgattg gtacttcgac tcgcgaacgg gtgcagttct tagcaaaaag aatggagaca
      541 tggttgtcaa tgagtatagt cgaatctact catatgctgt tcaaggaatg attcatttaa
      601 aatctttaaa ggcgcactgg cagataaagt catagaaaaa ctgtttagct ttatttttag
      661 ctcattttta ttgtgtacta ttattagaga gtgaaaggag aactttcatg aaaaagacaa
      721 caaaagcttt tatagcttta atgattctca taggagggct gcttatggtt tttagtttga
      781 atggcaaaag aacagaggaa caacaaaaaa aggatttaga aactagtatt gctaaactgc
      841 tggttcatga ctatgaagat gtcaaagaag ttaagtttac aggctgggga cattctcgtg
      901 aaacaggttc atggggaacg acggtgatta ttaatggtga gagtaggatg agcctgtctt
      961 ttgatcgttt atctggattg aaggaaatca gtggaagctc ttatcacccc gatactttta
     1021 agttagttga gaaatctgga atagaagagc tagaacccat aatgtataga gttagggata
     1081 tagaaaaagt gtcactaaag ggtattagaa ttatccattc tgctgaatga ggagagtaat
     1141 atgtcaatta cagatagtag ttatcatgag ttagcaagac aggcctataa tattgaacct
     1201 agtaaagcaa aggcgaataa tgctgatctt attattaatg atagaattat tattgatcgt
     1261 aaaactaaac gacaataccg agtcctctta gttcaggata ataacaacga cgcacataaa
     1321 accaatgaca acggtatgca agcaatggct gtagccccta ttgttcaagg tgatgtcgat
     1381 acctcccagg ttgtgattgc ctatgcaggg acaaatgctg cggattccag agatcttgat
     1441 acggattggc agctgctcat tcggggcaac caagatgatt tagtcagcgg caatattgat
     1501 ggtggcaatt ttgttattgc cgaaaaccaa ttacgatctg ctcaaaagtt ttatcaacag
     1561 gtcaaaagaa agtaccctca ttctgcctta acaaccacag gtcactctct cggagcttat
     1621 ctagcgctaa tagtcgccgc agaacataag atcccagcaa caacctttaa tggtccagac
     1681 cctgttcgcg gcatgtcagc tgaagccatc acatgggtta aggctaatag caatatgtac
     1741 aataatttcc gcattaattt cgatggtatt ggcaattttg gtgcctattt tggaactgat
     1801 gatttagcta tttctcggaa tgtcgacgct atgctcttat cagccaaccc tttgtattat
     1861 cacgatttag gagcttatcg ttttaatcaa aagggtcaga ttgtagatag agacggtaag
     1921 ctcattggaa cacaatacct tgtgagtcgg gcctatttaa atgtccttgc ctcaaaaaag
     1981 agcatgtcaa gctaccataa gctcaaaaaa cactggcagt ctaccggcaa ggggatcagt
     2041 ggctctgagg agctcttttt agatgcggca cagggaatgg tcctaggctc gtcaatggct
     2101 aaggctgctc gagagggggc tgatgaagct ttggatcata aaacagttgc agacgcaaaa
     2161 cttatggaag tgtggtcggc gattgacttc aactcttttc atgagctgcc ctactatgag
     2221 gtgcaagcct tgtttgcttc ttatggtatc acatatgacc gcttcgtccg agactttcag
     2281 gactatactc aatccaaggt cagcaagatg tcagccttgg ccacagactt tgaaaacctg
     2341 aatagagata ttcagacagt tattgatagc aagcttgaaa cggatcgtca gttagcagga
     2401 gagtttagag catggcagac agaattgtag aggaagtggc tatctatcgt aagctgcggg
     2461 agatggatga tgccgagcag gactttctcc gccagaaaaa agcctatcag aagcgtgaag
     2521 acagcttatc cgaaagaaga cgtgttttag atgatttgat caactctgag taccagaaaa
     2581 tgggtgcttt tttgaagcgt ttagacctat ctgccaatgc tgcatcagat tttttcaagg
     2641 aactggatcg cttaaaggat caatccaacg cagagtttca cctccagcgg gcagcccttg
     2701 aagaggagcg agcacagtca accaagactt ttcgtcaaga gcaggatcaa agagaggcag
     2761 agttattaga tatgaggaga gcttatgcta ataccaataa ctgagtatta tatcgaagaa
     2821 gaatacgcct atgccctgag gctaatgcgt caaatgctgg agcgtcaaag gattgccaca
     2881 gtggctaggc ttgcgaacag ccaaggtgaa gcgatcaaaa aaacgtttaa agaccagatc
     2941 aaagcgactg ccagccaaac taaggaaagc cttcagatca tggaagggca gctagatacg
     3001 gccataaaag gagcggtcag agatcagctg gagcaggtcg taaagaagaa gctgccgcag
     3061 tatgataggc tcaggtgagc taagcataag aaggattcct cgtagcgaca agtaagcttt
     3121 attgctgtgt tgaagttgct agtaattatt tatcagcagc ttctttggag ctttggtaaa
     3181 tatagtgtac ttgatgcttt gagcagtagg tatgatctct caaaacgctt cttgttattg
     3241 ctgttgataa agcattaaaa agcaggcaca tctaggagtt gaaaggctat ttctaaaatt
     3301 gtcaatagca gacttgacca atagcgagac agatgatgat tagaggacgt gttaggacag
     3361 acacgccctt tttgtttaga tatggtataa tgaaaaaaga gatttttggg agagctgaat
     3421 agctgaatca gtatctccct aaaaaggaaa tggttaaatt gtatgattaa attgatagca
     3481 acagatatgg acggaacctt tttaagagag gacggaactt atgacaagga gcgcttggca
     3541 gctctgttgc ctaagctaag agaaaaaggg atcctattta cagtttctag tgggcgttcg
     3601 cttttagcca ttgatcgctt gtttgagcct tttttagatg acattgccat tatcgctgag
     3661 aatgggtctg tggtgcaata caagagggac attctttttg ctgatgtcat gaccaagcag
     3721 cagtgtcatg acattgtaga gaaaattcat gccaatcctt attacaatca gtctgggatc
     3781 ctcttttcag ggcaaaaggc agcctatgtg ctcaaaggag ctacggagga ttatatccaa
     3841 aaaatgcatt attattatga aaatgttcag cttattgatt gtctgcagga tattgttgat
     3901 gacactgttt ttaaagcctc aacgaccttt acaggagaaa cagtcttagc tggcagtgac
     3961 tggctaaatc aggagctgtc ctatgcttct gcggtgacga caggctttga ttcgattgat
     4021 attatcctaa aagaggttca taagggcttt ggcatggatc agctgtgtca gcacctaggc
     4081 attttaccgg aaaggaccat tgcctttggc gataatctaa atgattatca aatgctgtcc
     4141 tttgcagggc gtgctattgc tactgaaaat gcaaggtctg aaatcaaggc catttctgat
     4201 caggttattg gtcattgtaa tgactcagca gtgttaactt atttggaggg attggtgtaa
     4261 atgacgcgtg ttaagctttt agctctagat ttagatggga ctctctataa taccgaaaaa
     4321 atcgttagtg atgagaacaa aaaagctcta gcagcagcta aggaaaaagg agttaaggtt
     4381 gttatcacaa ccggacgtcc tcttaaggct atcggaaatt tgcttgagga gctggatttg
     4441 ctaggtgaag agaactatag cattaccttt aatggcggtc tggttcaacg aaatactggt
     4501 catattttag ataaaagcgc tctaagcctt gctgaggttt atgacattca tcagcagttg
     4561 gcagcagttg gcttacctac tgatattatc agtgatggta ctgtttatag tctatcaggt
     4621 aatgatggca gacgctctca gtatcatttg gcaagtccct tgctgaactt tgttagcctt
     4681 aaatcatttg ctgagctgcc aaaggacatc acatacaata aaattgttac ggtgacggat
     4741 ccaaaggtct tggatcggca gcttgcaagg cttccaaagg ctatctttga ggattttgag
     4801 gcctttaaat cacgagacat catctttgag attatgccta aggggattca taaggcattt
     4861 ggtttggacc tgctttgtca gcacttgggc ttggaggcca agcatgtcat ggcgatggga
     4921 gatgaggcca atgactttag catgctgaaa tgggcaggcc ttggtgtggc tatggccaat
     4981 gcggttgatc aggctaagga agtggcagat gcagtgacta ccctaaccaa tgaccaatca
     5041 ggtgtggctg aggctatttg gaaatatatt ttaaatgagg aaggctaatg ggattatttg
     5101 aacgcttatt tggaaaaaag gataaggcta aggttgctga gcaagaggct gccactacag
     5161 aggtattgtc ggaggacata acgtcaaagg atacgattga gtctgaaaag gaggccttat
     5221 cagatacata tgctcatgca gtggtggctg atgtggtctc taggaccgat gacatcagca
     5281 aacaggctga gctctcagac aaggctgctt cagagcaagc tgaagggctt gatccagcag
     5341 ctagaggagc ttttctttta gaaagagagc cggagctaga gttagcagct actgatgaca
     5401 agaccttgga tcaggcaggt gagagcctaa gccagcacga ggctatggag gaggctaagc
     5461 atgatagggc taagtcagag catagtaacg agagcgcaga cgcatcaaca gaagatcagg
     5521 tcgagacaaa tgctgagtat caagtagcgg ctcaagcacc tgctggttca gctaatcaga
     5581 cagctgataa ggagccaagg caagagaccc tatcagctga atctgatcag gaaaaataca
     5641 agcgcagctt aaagaaaacc cgtacaggct tttcagcacg cttgaacagc ttctttgcta
     5701 actttagacg tgttgacgag gacttctttg aggacttaga ggagcttttg attctctcag
     5761 acgttggtgt tcatgttgcc acagccctga ctgaggaatt gcgctatgag gctaagcttg
     5821 aaaatgctaa aaagccagaa gccctaaagc gtcttatcat tgaaaagcta gtggctattt
     5881 atgaaaagga cggcctatac aatgaagcga ttcattatca gcaggatctg accgtcatgc
     5941 tctttgtggg ggttaatggc gttggtaaga caacatcaat tggaaagcta gcttatcggt
     6001 ataagcaaga gggaaaaaag gttatgcttg tcgctgctga taccttccga gcaggcgcgg
     6061 ttgcccaact ggttgaatgg ggacgacggg ttgatgtgcc ggtcattaca ggccctgaaa
     6121 aagcagatcc ggcctctgtg gtctttgacg gtgttgaaag agctgtcgcg gaaaaggcag
     6181 atattctctt gattgatacc gcaggccgcc tgcaaaataa agacaaccta atggcagagc
     6241 ttgaaaaaat tgggcgaatc atcaaacgtg tcatacctga tgccccacac gaaaccctgc
     6301 tagcgctcga tgcctcaacg gggcaaaatg ccctgagtca ggctaaggag ttttcaaaaa
     6361 ttacacccct cacaggcttg attttaacca agattgatgg tacagctaag gggggaattg
     6421 tcctagctat tcgtcaggaa ttggatatcc cagtgaagct gattggcttt ggtgaggcta
     6481 ttgatgatat cggtgaattt cactctgagg actttatgaa gggactatta gaaggtatac
     6541 tttaagagga aagcctcaga ttatcggctg ttggccaaag agaatgaggg ggttcgttta
     6601 gaggcaaatg ttaaacagcc ttttgaaaac gcttgacagg acctttagga gatgataaaa
     6661 tgaaaacgtt attagatgtg attacttagg gtaagcgtgc taatgacaaa tgaatcagaa
     6721 tattaaagga tgttatcaca gttttgtgag cagggaccta ttccagtgtg accttttggc
     6781 atgctgtgga taggtcattt tttattgtga agcaatgagg gactaggact tttatgatta
     6841 ttaaacgcgt tttaaaccat aatgcagcga tttcaaccaa ccatcagggg ctagatattc
     6901 ttttgatggg aaaggggatt gcttttaaga aaagaattgg tgaccatatc gatagtgaag
     6961 ctatcgaagc gtcatttgtt ttaaaaaata gtgacaatat gaaccgtttt actgaattat
     7021 ttattgctgt tccgcaagag gtggttgctt gctcagagag gcttattaat ctagggaaaa
     7081 ttaagctggg taaaaattta gatgaaatac tctatatcaa tttgacagac catattcatt
     7141 cagctattga aagacataag cagggggtta tcattagtaa tcccttgcgt tgggagattc
     7201 aacggtatta tcctgatgaa tatgcgattg gtgttaaggc cttagaggtc attgccagtg
     7261 agctaggagt cgctctggct gtagatgaag cttcgtttat tgcgatgcac tttgtcaacg
     7321 cgagccttga taatcctttc aaggagcctc atcgaatgac agaaattgtg tcttacattg
     7381 aacagaaggt caaggctgat tttaagacag agcttgatga agcctctatt gattattatc
     7441 gctttatcac tcatgtgaag ctatttgccc agcgcgtgtt atcaggcatg gcttatgatg
     7501 atgacgagac tgatttgctg ctggtggtta aggataaata cccagaggaa tatcactgtg
     7561 ttaggcaaat tagccatcac atgaaaaaag tataccatta tcagcttagc tctagtgagc
     7621 ttttgtattt aacggttcat atcaaacgtt tagtcaaaaa tgtgaaggag taatgaaatg
     7681 acttatcaag aaacagccaa ggccattttt gaagcagttg gtggtgagca gaacattcaa
     7741 gaggtaaccc actgcatcac gcggttacgc ttggttttga aagatgataa acaagtggta
     7801 gatcaaaaaa tcaaacttat tcctaatgtg attggagtca tgcgccaaaa cggtcagtat
     7861 caaattattt taggaaatga tgttaacaat tattataagg catttatgac cctagggcag
     7921 tttcatgaaa ctgatatgag ctctagcgct ggtcaaaagc agtctgttat tgaagggctg
     7981 attgagacga tagctagcgt tattacgccg cttattcctg ccttgttggg tggtggtatg
     8041 ctaaaagtgg ttgggatctt ggtgcctatg cttggtctag caggtacgga ctctcaaaca
     8101 gttgctttta ttaatttttt tggagatgct gcttattatt ttatgccaat catgattgca
     8161 tattcagctg cggcacgctt taaggtcaca cctgtattag cagcaactgt tgcagggatt
     8221 ttactacacc cagcttttgt tacgatggta gctgcaggta aacctatggc tctgtttgga
     8281 gcgccggtga cacctgctag ctatggtgcg tcagttattc cgattttaat tatggtttac
     8341 ctgatgcaat acattgagcg agaggttaac cgttttgtac caagtgtgat gaagagcttc
     8401 ctgcagccga ccttgattat ttttatttca ggctttctag ccttagttgt tattggacct
     8461 ctgggtgtta ttataggaca gggcttgtct aatagcctgc tagcaattta ccatattgct
     8521 ccttggctgg ctcttgctat tttaggtgca attatgccgc ttgttgttat gacgggtatg
     8581 cattgggcct ttgctcctat ttttctggcg gcctctgtag caactccaga tgttttaatc
     8641 ctcccagcaa tgctagcctc taacctagct cagggatcag cagcggtggc tgtagcatgt
     8701 caatcaaagc aaaagcaaac ccgtcaggtt gccttagcag caggcttatc agctttattg
     8761 gcaggaatta cagagcctgc tctttatggc attactctaa agtttaaaaa gccgctctat
     8821 gctgcaatga tttctggtgg ccttgtgggc gcctatattg gctttgttaa tatagcctct
     8881 tatacttttg tggtgccatc actaattgga ttaccacaat acattagccc gactagctct
     8941 gctaatttta ccaatgcctt aattgcagcg ggcttaacaa ttgctctaac ctttacatta
     9001 acctggtttt ttggcattga tgaggaggtt gaccaggagg ggtcagctga ctcggatagc
     9061 acgccagtaa aaagtggctt atcagcaaag caatctattt atgctccgat ggttggcaca
     9121 gtgcttccat tatcagaggt gccagatgaa accttttcgt ctaagctttt aggagagggg
     9181 ctggctattt tacctaatga ggaatatgtc tatgccccat ttgatggcga ggttatcacc
     9241 ctttttccaa caaagcatgc tattgcttta aagaacgcca agggagttga cgtcttaatt
     9301 catgttggta ttgatacggt tgagctaaaa ggacagggct ttgagcagct ggttaaggct
     9361 ggtgatgctg ttaagcaggg tcagccgcta ttacgtgtag atcttgagtt tatccgttct
     9421 aagggctatt ctttagtgac tccatttgtg gtgacaaata gctctgagca gctcgaaatc
     9481 attgttaatg acaacaagga gcatatcact cagcatgatg ttgctctcgt tattctctaa
     9541 agagatgaat tgaaggagga gataatatgg tttgttttcc aaaggatttc ttgtggggag
     9601 gggcggttgc tgccaatcag gttgagggag cttatttaac agctggtaaa ggcttgtcgg
     9661 ttcaggacgt tttaccagaa gggggcttag gagactatac agctgagcca acagcagcta
     9721 atttgaagct agaggccatc gatttttatc accgctacaa ggaggacgtg gcgctctttg
     9781 cagaaatggg ctttaaggtt ttccggacat caattgcttg gtctcgtatt tttcctcagg
     9841 gcgatgagac agagcctaac gaagcagggc tacaatttta tgacgatttg tttgacgagc
     9901 tgatagcaca tggcatagag cctttagtga ccctatctca ctacgaaacc ccactgcacc
     9961 tagctaagac ctacaatggc tggacggacc gtcgtatggt tggcttcttt gaacgttttg
    10021 cgacaactgt catgcagcgc tacaagaaca aggtcaagta ttggttaacc ttcaatgagg
    10081 ttaattcaat cctgcatatg ccttttacca gtggtgctat catgacacca aaggaaaagc
    10141 tgactccgca ggagctttat caagcgattc accatgaatt agtagcgtct gctagtgtga
    10201 caaggcttgc tagattgatt aaccctgctt ttaaaatagg ctgtatgatt ttggctatgc
    10261 cagcctatcc aatgacctct gatccgaggg atattttagc tgcgaagcag tttgagcaac
    10321 gtaatctcct gttctcagat attcaggtca gaggaaaata cccttcctat gctaaatcct
    10381 tttttaagga gcagcacatt gacattcaat ttgaaccggg cgacagtgag cttttggcgc
    10441 agcatacggt tgacttttta tcctttagct attacatgag tgtgactcag tctcatcacc
    10501 cggatcatta tcaacgaggg gagggcaata ttttaggtgg cttggttaat cctcatctgc
    10561 cctcttcgga atggggctgg caaattgatc caattggcct tcgcataacc ttgaatgatt
    10621 actatgatag gtaccaaatt cctcttttta ttgtggaaaa tgggcttggt gccaaagata
    10681 agctagtaca gacaaaagat ggtcactgga cagttcagga cgattatcgg attgattaca
    10741 tgaggcagca tttattgcag gttgctaagg ctattgagga cggtgttgac attatgggct
    10801 atacctcctg gggctgtatt gattgtgttt ctatgtcgac tgctcagcta agtaagcgtt
    10861 atggctttat ttatgtcgac cgacatgatg atggcagtgg tcacttgaca cgctacaaga
    10921 aaaaatcctt tgcttggtat caaagggtca ttgagaccaa tgggcgtagc ctgtctgagg
    10981 agagctagaa agtagcctca aaggctttac caacagtagc aaagccgtat agcacacgtc
    11041 ttttaaaagg ctgatgctat acggctttta gccatttcat ttaaatggaa cgaactcaat
    11101 tacgtctttg tactgtcccc taacaaaaag cctccataga cctgtgtcat aggtgtggag
    11161 gcttaatgct tgttaaaata ccctatagac ataagggtta tcaggctctg gggcttggtg
    11221 tgcttcctcg atttgaagga caggaagctg ctgctctaag gttttgtcat attccatgtg
    11281 aatctggcct ttgacggtaa gccaagtgtt gttggcatag ctttcttgat taccagtggt
    11341 cagaagccca tacacaccgg aatcagcgat acaatggata atcccaaatc taaagaggaa
    11401 ttgatagctg tcatgtcctg gctcattgta gacaaagcca gtgtactgaa tcgtacgatc
    11461 aacgaattcg tctgggtaaa ggtagattaa ttccattacc tccatataat tgtcagtggt
    11521 aatggtgatg gctgatttgc cttggtattt tttcagctca ttgagcattt ccttttgata
    11581 ggcggatttg gtaaagtaca ggctggtgtc tggctttagg tattgaatgg tagtgccatc
    11641 atcactgacc cctgtttttg aagcgcctgc ggctaatgga aaggtatagc ccttggcggc
    11701 aacggtcgtc gaatccaagc tgactgtagg tactaacaag ccaaccaaaa caggaaagac
    11761 caggataagg ggactggtca gctgagcgac cttacctttt aaatgactgt gtagcttgat
    11821 gtttttagtc caagtgtata gctgcaccaa tgcaaggata aaggatagaa ccatagaaat
    11881 ataggctaag taagcgtaac gaatattgat atattgattt agcttgccag atagctctag
    11941 atacatggtc aactcaaaat agcctgctaa aattaaaaag cgaatcatca cagcaccccc
    12001 acaagtaagc aatatatggt aatcatcaca gctgatacac tgacaaattg aacaataaag
    12061 gctcccttaa aggaattgag catcatcatg aggtttttga tgtcaaccat agggccgatt
    12121 aagagaaagg ctaaaacagg agcaactcca aaggttgaca ataacgaagc tccaataaag
    12181 gcatcagcct cactgcaaag agataggata aaggctaaga gcatcatgac taagatggct
    12241 gtcaaagggc tatgtccgat cgctgtcagc acctttgttg gcagataaat ctgcatggct
    12301 gaagcaatca gggtcccaaa gactagatac cttcctgtat caaaaaattc gtcaatagcg
    12361 tgagccagtg ccaagtaaag ccgttttggc agactttcgt gactgtatgt atgacaatgc
    12421 accggctggg ctgattcctt aagaatgttc tcatcaacaa tgaaggctag catgatgcca
    12481 aggctgacag ccactaaaat agcacctaaa agccttagca tgagaaagcg cagtgaattc
    12541 ccaaaggcag aataggtagc aaataaaaca atcggattaa taattggagc ggttgctaaa
    12601 aagggaacag cagtgtagct aggcaccttc ttttttaaaa aacgattaat aatcggaatg
    12661 ataccacatt cgcaggaagg aaaaacaaag ccaataaagg taccaaataa aattcttagc
    12721 cacttatttt gagggaggta tctttgaact aaatcaggcg tgacgaaaac ctcaatacag
    12781 ccagataaaa tggtccctaa aaatacaaaa ggcagagcct caataataat ggatagaaaa
    12841 atcgcaaacc actgaagcac gctgggtggc agatttgaaa aaagcgacat tcaccgtatc
    12901 ctttctatat gttcacgacg ccaataaggg ctagtcctgc ttaactgtct tggcctgcgg
    12961 ctttggtttt tcagtgacta gctttccatc ttggttaagc tctaaaggct tatcaaaatc
    13021 tgggatagac gcaaagcctg ccatcatctt ttcgagctgg tcatttttct tatgagtaat
    13081 tgccataggt ataccttctt tcaatcaata tagctctatt atacaatcat ttgacggtaa
    13141 agccaaagct aaaacatctt tttatcttct gattgatttt aggcttcagg ctgtcaagca
    13201 gtgtgtcatt agattgactg acaaatatga tacaatgtga ctgataggag ttatgaaatg
    13261 acaaaacgag tattattagt agatgatgag gagcctatct taaggctact ggattatcat
    13321 ttggccaagg agggctttgt gacagagatg gtaacagatg gccgtactgc cttggcatta
    13381 gctgaaagag aaccttatga ttttattgtg ttagatatta tgctgccgca attagacggt
    13441 atcgaggtct gcaaaaggct tcgtgctaag ggaagcaaaa ccccaattat gatggtttct
    13501 gctaaaagtg atgaatttga caaggttttg gctttggaac tgggggcaga tgattatgtg
    13561 accaagccct ttagtcctag agaattatta gcgcgtgtca aggctatttt aaggcgcact
    13621 gaagcagaga tttctggtga tggtgaggag cgtcgtgagc ctttttatac gatgagtcaa
    13681 ttgcgtctgt acccagagcg acatgaggtc tataaggaca aggagctatt gccgttaacc
    13741 ccaaaggaat atgagctact gctctatctc atgaagcacc ctaatatgac cttgacgcgt
    13801 gagcggctat tagagcgtat ctggggttat gactttggcc aagaaacacg tctggtagac
    13861 gttcatattg gcaagctcag agaaaaaatt gaggacaatc ctaaggcgcc tcagtatatt
    13921 caaaccattc gcggctatgg atacaaattt aaggagctaa agaatgatag gacatcttag
    13981 gcggttgagc atgttgctag ggctttgctt gcttgctgct cttggtctga tttggcaagg
    14041 accgcatcag gtgctgactc tgatagtgct gtgtactggt ctcgtagcta gcttttatgt
    14101 cttgattatg ctgtttagat gggagcgtga attcagagcc ttgcaccacc atcttttgac
    14161 agctagtgac cattttctcc tagtggggca ggctgattta agtgcttatg ctaagcagct
    14221 gacagagcta aaaagtgacc tattacaaaa ggaagcaagg ctaaaagcct tatcaaaaaa
    14281 tgtggaggct gtaacctctc atctcacgat gggcatgctt ttagtctcca atcaaaggga
    14341 gctgttgctg accagcaaat ccttaccggc ttattttcca gaggctaagc caccttttgc
    14401 ggtcttggag gatcttaaac gaatagatct ggtagcttta gttaatcaag tctttgacca
    14461 aaagcagaca ttaaagaagg aattaacagg cctacatgat ggtgatttga tcttggaggt
    14521 tacccttgtg cctatcttta accagtcgca tgttgtcaag gaggttttag tgctcttata
    14581 tgatctgacg gccattcgtc attatgagag gctaaatttg gagtttattg ctaatgcttc
    14641 tcacgaatta agaacaccgg ttacatcgat caagggcttt gctgaaacga ttaaggaaat
    14701 gcctgacgat gaaacaagcc taaaagaaga ctttttagac attatctaca atgaaagcct
    14761 gcgtctagag cgtattgttg agcacctgct gaccttatcc aaggctaaca agacaccgct
    14821 tgacctgacg gagtttcagc tcaggagctt cctgctgtat acaggtcaga gcatgaggcc
    14881 acagttagag caaaagcagc ttgagctaag ctatgcattg gaggattcga ttgttgtgac
    14941 atctgatcaa tacctcttat cgcagatcat gttaaatctc ttatcaaatg cgatacagta
    15001 tacagacaat gggggcagaa ttcagctatc cagtcaaagg gttgctggtg gtgttgccat
    15061 tacggttgca gatactggga ttggcattag ccaaattgag ctagatcgta tttttgagcg
    15121 cttttatcgt gttaacaagg gacgcagcag gcaaagtggt ggaacaggcc taggcctagc
    15181 cattgtaaag gagctgagtc agcttcttgg cggtcagata acagtcacaa gtcagctagg
    15241 agagggtagc caatttacct tattcttacc agaagctatc aacaagtaaa cagtcactac
    15301 cagctgctta aggctagtct tggtagtggc tgttttaggt tttacaaaat ctttacatta
    15361 atcagggata aacctttaca aagacctgat aagctatagg tgtagcaagc ctacaacaca
    15421 atatcataaa agataagggt gattcttatg acaatcaaaa aaatgctgat catggcagct
    15481 attggcttat caggcttagg tcttgcagcc tgtggcaata acagtgctga tgctggaaaa
    15541 gcagcagaca ggattgacct tgtttctcga gaaaatggct caggtactcg tggagccttt
    15601 accgaaatga caggcatcct aaaaaaggat ggtgacaaag agattgacca aacagcaaaa
    15661 acagctatta tccaaaatag cacagaaggg gtcatctcct ctgttaaggg aaatagtcgt
    15721 gccattggct acatctcgct agggtcctta aatagcgacg tcgcagccct aaagataaat
    15781 ggcgtaaagg ctagtcgtga gactatttta gaggggaaat accctctgca gcgtcccttt
    15841 aatattgtat ggtcctcaga cctatcagga gttggtaagg attttatcac ctttattgac
    15901 tcaaagcagg ggcaggagat tgttagagac aatcgattga tcgaagcaaa aacagacgcg
    15961 ccagcctaca gcagtaaggg cttatcaggc aagctgtcaa ttgtgggctc aacctcagtt
    16021 tctcccttga tggaaaaatt agcagaagca tacaagaaag aaaatccagc cattagcatt
    16081 gatattacct caaatggctc atcagcaggt atcaccgccg ttagggaaaa aacagcagac
    16141 atcggtatgg tttctcgtga cctaacagct gaggagagca agggcttaac tgatgatgcg
    16201 attgcccttg atggtatcgt agtgattgtt cacaaggaca ataaggtaag taatattggc
    16261 atagatgtgc tggctgatgt ctttagcggc aagctaacaa gctgggacaa ggtcaaataa
    16321 agaacgatta gaaggaaggc aaagaagagg tgttttattc ttgctttcct ttcttagaaa
    16381 ggatcatcag tgaataaaca agcctttaag gaggattttt ttaaagttat cttctttctc
    16441 agtgcagcga tggcagtcat tgctatttgt ttaatctgta tctttatttt tagtaatggc
    16501 cttcccttta ttgctaagta tggtatgaga gcctttttgc taggaaatga ttggtcaccg
    16561 tcaaatcagc cggcaagcta tggtattttg ccgatgattg cagggtcttt tgtcatcaca
    16621 cttggtgcaa tggtgattgg tgtaccaacc ggtatattga cctcagtttt tatggtttac
    16681 tattgtccta aagcatgcta tggcttttta aagtcagctg ttaatctgat ggcagccatt
    16741 ccgtctatcg tttatggctt ttttggtctt caagtgctag tgccttggat taggagcttt
    16801 gctggtaatg gcatgagtgt gctgactgcc tccttgctct taggaatcat gattttgcca
    16861 acgcttatca gtctttcaga gtctgctatc agagctgttc caaaggctta ttattcagct
    16921 agtctcgcac tgggtgccag tcatgaaaga agcatttttc gagtgatctt gccagcagcc
    16981 aaatcaggcc ttttttccgc ccttatttta gggcttggtc gtgccattgg tgagacgatg
    17041 gcagttattt tggtagcagg aaaccagcct gtgctgccat caggattatt tgagggcaca
    17101 agaaccatga cgacaactat tgtcttagag atggcatatg cctctggtca gcatagagaa
    17161 gccttaattg caacatcagc tgtcctcttt ggctttattc tcatcattaa tgcttgcttt
    17221 gcttatgtga aaggaaaatc aactcatgac taactatttg ctaaaagccc tggtctatct
    17281 tttggcgcta ttgacctttg gctccttatt tttgatcatt gcctttatgc tggtaaaagg
    17341 cttgcctaac ctctcattat ccttattttc atggacctat acctctgaca atgtttctct
    17401 aatgccgtcg attatctcaa ctgttagtct agttttaggc accttagtgc tagccttgcc
    17461 cattggtgtc tttgctggct tctatcttgt ggaatatgcc aagcaggatt cactatgggt
    17521 aagggcaata cgtcttgcag ctgacacact atcagggatt ccgtcgattg tttttggtct
    17581 ttttggcatg ctgttttttg tgttttttct tggcctgcaa tattctcttt tatcaggtat
    17641 tctgacgtct gtaatcatgg tgctgccagt tatcattcgg tcaacagaag aagcactcct
    17701 ctctgttagt gatcacttgc gtcaggctag ccttggctta ggagccggta agctaagaac
    17761 catttttaaa gtcgtgttac cagctgctat acctggtatt ctagccgggg taatcctagc
    17821 gattggacgt gttgtgggtg agacagcagc cctgatgtat accctaggca cctctaccaa
    17881 tacaccaacc agtctcatgt catcaggacg ctcactagcg cttcacatgt acatgctgtc
    17941 tagtgaaggg ctacatgtca aggaagctta tgcaacgggt gttatcttac tcataaccgt
    18001 cttactgatc aatgccctat caagcttgtt atcacgccga ttagtgaaag gagtcgtcta
    18061 aaatgggagc tttttcaacc aagcatctta atgtctttta cggagatttt caggccttaa
    18121 aggatatctc cattgacata ccagaaaagc agatcacagc cctgataggt ccctctggct
    18181 gtggcaaatc aaccttttta aaaaccctaa atcgcatgaa cgatttgatt ccttcctgtc
    18241 ggattgaagg ggagattctc ttagacaatc aagacatcta tgctaaagca ataaacctca
    18301 atagcttacg taagcgtgtt ggcatggtct ttcagcagcc taacccattt gccatgtcta
    18361 tttatgataa tgtggcttat ggtcccagaa cacatggcct taaagacaag aaaagcctag
    18421 atcagctggt cgagcaatcc ttgagaggag cagccatttg ggacgaggtc aaggacagct
    18481 taaaaaagag tgccctgtcc ttatcaggtg gacagcagca gcggctgtgt attgcaagag
    18541 cgcttgctgt ggaacctgat gtgttgctca tggacgagcc tacctctgct cttgatccca
    18601 tttctacctt aaaaattgag gacttggttc agcaattaaa gcaggattac acgattatca
    18661 tcgttaccca caatatgcag caggcttcac gcatgtcaga taaaacagcc tttttcctca
    18721 caggagatat ttgtgaattt ggcgatacag ctgaactatt tacaaagcca aaggacaagc
    18781 gcacagagga ttatatttct ggacgcttcg ggtaaggaaa ggatcaggcg atgagagagc
    18841 aatttgaatt agaattacag cagctagagc agcaactatt agctctagga caggctgttt
    18901 tggcagctac ctcaaagtcc ctgctagctc ttgctgcaag ggatcatgag atggcaagtc
    18961 gaatgattga ggaagatcac acaatcaatc aggctcagtt agatatcgaa ttggcctgtg
    19021 ctagattgct tgccttgcag cagcctcagg ctactgatct tcgttttgtg cttgtggtca
    19081 tgtcagcctc ttcagactta gagcgaatgg cagaccacat ggtgagcctt tcaagggctg
    19141 tccttcgctt gaaggccact catcagctgt cagaccatgc tatcgcagaa caagtccatg
    19201 ctcttggtca aaaagctcag cagcaattgg cacagctctt agctgtcatg agctcgcatg
    19261 atacacaaaa agcgattgcc cttgccaaag aagacaaaca gatagacgat caatacaaga
    19321 ccttgtcaag agatatgatg agcttaatga aggaccaaac aatagctatt tatcagggca
    19381 cagaatattt atctatgctg aggcatatag agcgctttgc tgatgatatc actagtattt
    19441 gtgagcgtct ggtttacctt gaaacaggag aaatcatcag cctaactgac acttaagcct
    19501 ctttcttaat tgctgtcttt tatgctgccg ttaaggctgc tgggaggcta gtattcatag
    19561 aaagaaagtc ttttatagag tgatgctttt gtttctctag taagtgtaac tatctatttt
    19621 cagaaaaaaa tcactaaaat tagatctata tatatatcta tattagtaaa atataatcta
    19681 gttaacatta tataataact atataaaaaa tagataggag ttatatcatg aaaaaattac
    19741 tattaactag tgctgcggcg ctagccttag caacagtagc agttagcaca acaaaagtag
    19801 aggcagcttc tcattctaaa catgtaatcg aacatagtat taacgacacc aagtcgctta
    19861 gtgcagcgcg ctggggctca agactgcaga tcctcaattt gttaacacag tataaggaga
    19921 aattgagagg cggtggtttt tacttttatc aaagaaaatt tagagctgaa gtaggtaaag
    19981 caaaaacccc ggctcagatt gaggagcttt atgacaagtt tagagaagaa ctggaaaaac
    20041 tcgcttaatt ttgactaacc actaagtagc taaaagacga tttccgtttg gagatcgttt
    20101 tttcttagcc tttagaagta gccgaaaaga taagttttgt tttcttgaca cttatttgtc
    20161 ataaagcttt tatcttgttc tatccctctt tctttgtgct ataataagaa ctgttatgga
    20221 aaatatgaat catcaaaaca tttcagaagc gttgggggtc accccaaaac agattagtca
    20281 agtacttgcc cttaccgctg agggcaatac cattcccttt attgcgcgct atcgtaagga
    20341 agccacgggt aaccttgatg aggtggtgat caaggctatt attgatatgg ataagtctct
    20401 cacacagctt aaggagcgta aagacaccat tcttgctaaa attgaaggac aagggaaact
    20461 aacagctgcc cttaaggaag ctatagaagc agctgataaa ttggctgacc tagaggagct
    20521 ttatttgcct tacaaggaaa agcggcgtac caaggcaacc attgctcgag aagccggctt
    20581 atctggacta gctagactga tccttcaaaa tgcacaagac ctagaagcca aggcagaagc
    20641 ctttatcaca gaaggctttc cagagccaca ggcagccctt gctggagctg ttgatatttt
    20701 agtcgaagcc atgtcagaag atagcaggct aaggtcctgg acctacaatg agatttggaa
    20761 gtatagccgt ataacctcta gcctaaagga agccagctta gatgacaagc aggtctttca
    20821 gatttactat gagttttctg agacggtatc taacatgcag ggctacagga ccctagctct
    20881 caatcgtggg gaaaagctag gcgtattaaa ggtatccttt gagcatcata tagacaaaat
    20941 gctgcgcttt ttcagccttc gctttaagga gcacaatgct tatattgatg acgttattaa
    21001 ccaaacaatc aagaaaaaaa ttgttcctgc tatggaacga cgtatccgca cagaattaac
    21061 tgaaatggct gaggacggtg ctatcaagct cttctcagaa aatctgcgtc accttttgct
    21121 agtctcacca ctcaagggaa aaatggtgct gggctttgac ccggccttta ggacaggggc
    21181 caaattagcg gtgattgacc cgactggaaa gctgttaacc actcaggtta tctatccggt
    21241 ggcaccagct aatcaagcta agattcaagc agcaagagta gctctagctc agctcatcac
    21301 tgactatcag attgatatta ttgccattgg taatggtaca gccagtcgtg agagtgaagc
    21361 ctttgtcgca gaggtgctaa aggattttcc agaaacctct tatgtcattg ttaatgaaag
    21421 cggagcttcg gtttattcgg cctcagagct agcccgtcat gaatttccag agctgcctgt
    21481 tgaaaagcgc tcagccatct ctattgcgcg tcgcttgcaa gacccgctag cagagctggt
    21541 caaaattgac ccaaaagcaa tcggtgtcgg acaataccag catgatgtta gtcagaaaaa
    21601 gctatctgag catctggatt ttgtcgttga taccgttgtt aatcaggttg gggttaacat
    21661 caatacagct agtccagccc tactggctca tgtttcaggg ctaaataaga ccatttctga
    21721 gaatatcgtc aggtatcgtg aagaaaatgg agagatcacc tcacgtgctg agatcaaaaa
    21781 ggtccctaga ctaggcgcaa aggcctttga gcaggcagca ggtttcttgc gtattcccaa
    21841 tgctaagaat atgctagaca atacaggcgt ccacccagaa gcctatccag ctgtcaaaaa
    21901 gctctttcaa ttacttgcga ttaaagacct agatgagccc gcaagggcca aattacaggc
    21961 ggttaatctt gaagaaatgg cagagcaatt gacgcttggt caagaaacgc tcaaggatat
    22021 cattgctgat ttgctgaagc caggaagaga cttgcgtgat gactttgaag ctcctgttct
    22081 tcgaaaggac attttgagtg taaaggatct ggctgttggt caaaggctag agggaactgt
    22141 tagaaatgtg gttgacttcg gtgcttttgt tgatattggt gtacatgaga acggtttgat
    22201 tcacatttca gagatgagtg aggcctttgt caatcaccca agtcaggtcg tttctgtcgg
    22261 agatttagtc actgtttggg tttctaaggt tgacttagac cgccacaagg tcaacctaag
    22321 cctagtgccg cctcgtgacg ctgactgatt atgttagaga ggtctcgcta gctgattttg
    22381 gaaagccctt taagcatcag gcttcttgga acagacgact aagaacaaca ggcggacgtt
    22441 tttttccaaa ggatggtcat ctggatttca atcccaaaat cttagaggag catggggaga
    22501 ctgtctttag acagatcgtt aggcatgagc tttgtcatta tcacctctat tttgaggggc
    22561 tgggctttcg gcataaggat caagccttta aggagcttct agaccaagta gacggtctga
    22621 gatacgctcc aaaattacag tcacatcaag ctaattacct ctacatctgt caacattgcg
    22681 gccaagctta tgaccgaaaa cgccctatca atctggcagt atttgcctgc ggcaggtgtc
    22741 atggcaggct cattgaaaaa aatcagtcgt aaggctgatt ttattttgct aaaaaaggaa
    22801 taaactagta tcatagaata aggaggtgag gagacatgga atctaaattt tataagcaac
    22861 gaaagcataa gctagtggct ggagttatct ctggtttagc tgataaatac ggctgggatt
    22921 tgcccctagc tcgtgtgctt gccgccttat tgatctattt tactcgcttt ggggttgtta
    22981 tttatattct tttagccatc ttcctaccat ataaagagga cctacttgaa gaacgttacg
    23041 ggagaggacc aagacgtcgc aaggatgctg atgtcctaaa tgatgaagat gaaggctggt
    23101 tttggtaaga ccacagcgag cgactattaa aagcttgaca ggaattttaa tagtgcctct
    23161 agcgttatta tcagaaataa agctggctgt aggcctttat ctgatgagat agggcctttt
    23221 tgttgtttgt cctctttagg ctagtgcctg ctttaagtga gctgaggcag ctgctgcagg
    23281 attctttttt agtatgatca agcactttga aagcttcttt gaaaaataag tatttgtaag
    23341 ggcttagata gtgatttatg atataatatt aaaaaaggag aaattatgac agttaccgtt
    23401 aagatgttag tcacaaaggt caagcttgac gttgtctatg caaccgatga cttgctagaa
    23461 aaggagataa cgacctcaga tatttcgcgt ccgggacttg agatgaccgg ctattttgat
    23521 tactatgccc cagagcggct ccagctgttt ggtatgaagg agtggtccta tctcactcag
    23581 atgacctcac ataaccgcta ctcagtttta aaggaaatgt ttaaaaaaga cacgccagct
    23641 gtgattgtat ctagggggct agctattcca gaggagatgg ttcaggcagc gcaggaggaa
    23701 ggcattgcct tgtttagcag ccgcgtatct accagccgct tagctggtga gatgtcttat
    23761 tttcttgatg cttccttagc agagcggaca agcgtgcatg gggtgctgat ggatatatac
    23821 ggtatggggg tactgatcca aggtgattca ggtattggta agagtgagac aggcttagag
    23881 ttggtcaagc gtggtcatcg cttggtggca gacgaccgag tagatgtctt tgccaaagat
    23941 gaggagacgc tatggggaga gccagcagag atcttacgcc atctcctgga gattcgtggt
    24001 gttggcatta ttgatgtcat gtcgctgtac ggtgctagtg ctgtaaagga ttcctcacag
    24061 gtgcagttgg ctatttattt ggagaatttt gaggcaggca aggtttttga ccgcctgggc
    24121 aatggcaatg aagagatcac cttttctggt gtcagtattc caaggattcg cattcctgtt
    24181 aaaacaggtc gaaatgtctc agtggttatt gaggctgctg caatgaacca tcgtgcaaaa
    24241 gagatgggct ttgatgccac caaaaccttt gaggagcgcc ttacacgctt aatcagcaaa
    24301 aatgaggagg gcaaatgatc aatccaatag cctttaagct tggtcccctt agtcttcact
    24361 ggtatgcggt ttgtattttg gtgggattgc tcttagcggt ttatttggca gccaaagaag
    24421 ctccgcgaaa aaaaatgacc agtgatgata ttattgattt tattctgatt gcctttcctt
    24481 tggcaattat tggagcaaga atatattatg tagcctttga atggtcctat tattctcagc
    24541 atttgagtga catctttgct atttggaatg gtgggattgc tatctatggt ggcctgataa
    24601 caggtgctat cgttctcttt gtttattgct actataaggt gctgaatcct atccatttct
    24661 tagatattgc agcgcctagt gtcatgcttg ctcaggccat tggcaggtgg ggaaatttct
    24721 tcaaccaaga ggcctacggt aaggctgtca gccagctcaa ttacctgcct agctttattc
    24781 gccagcagat gtttatagac ggcagctatc gtgttcccac ctttttgtat gaatccatgt
    24841 ggaatctgat tggctttgtc attatcatgg tgtggcggcg taagcccagg tcattagtag
    24901 atggggatat tatctcattt tacctgattt ggtatggctg cggtcgattg gtgattgagg
    24961 gcatgcgaac ggacagcctg atgcttttag gaattcgtgt ttctcaatac gtgtcggtgc
    25021 tgctcattat cattgcgatt gtttttatct ttaaaaggca tcgacaaaag ggaatttctt
    25081 attatcaaga atagtgatag aaagaggaga cgtttatgaa tttagtgggc atttcattgc
    25141 tgataatcgc attagccttt gtagctctgg tgattttttt gattatagtg ttaaaaaagg
    25201 tgtcagaggc agttgatgag gctaaaaaaa ccattaccgt tttaacgagt gatgtcaatg
    25261 ttacccttta tcaaaccaat gaaatattag ctaaggctaa tgtgctggta gatgatgtga
    25321 atggtaagat gacaacaata gatcctctct ttgttgctat tgcggatttg tcagaaagtg
    25381 tttctgattt gaatgtgcag gccagacatc ttggacgtcg ggcgacaaat gccacaagca
    25441 atgctgcaaa ggtgggtaaa gtagctcttg tcggcaaggt cgcttctaaa ttatttggta
    25501 aaaaggagaa aaggtcatga gtaatttttt aaaaacgttg gtgattggtg cagcttcagg
    25561 agcagctgcc gcttatttct tgtcaactga aaaaggaaag gtcttgaagg cttgcgcgca
    25621 aagagcctat gaagcctatc gtcaaaatcc tgaggaatat catcaaatgg ctaaagaaaa
    25681 aggaagtgag tacagtcagc tggctcgcca tacctttaat gatttaaaga ccaggtttga
    25741 atcaggggat atgaccactg atcaggtgtt tgattttatc aaggaaaaga ccagccaatt
    25801 tgttcatcag gcaaaggaag ctacttcaga gcatgacaag gctgatgatg tgatcattga
    25861 cctgaacgaa gaggatatta ttatcaacta tcctgaagat gattcagaaa aagaagcaga
    25921 tagcaataag tcttaagaat aataaggcaa aataaggacc ctctcagcta tggagggtct
    25981 tttgtagtgc aggctacttg tctattcaag ggcaataggc aataagggta atgaaaaaag
    26041 agcttagtct cgccaagctc taactgttta tgacattaat aatgtgattg cttttgaaag
    26101 aaaggaagta atggctaggc tgatagcgct agcaatgaga aaggcccaaa ccggtgccaa
    26161 attcatgaca agaaggacaa atgcaaacaa gacagtgatt aaactaaaaa cagcaatacg
    26221 ggcaaaaaaa ataagttcct tgagcttgct actgtgtcca ttgaggtctt gaaactcttg
    26281 aaatttttgc tgcgagacct gctcttgctt ctgctgcttg agctgccgct gctccaatgg
    26341 tgtaggcata gtcctctcct ttcccgtaag atacccaacc attttaccat aaaagctgat
    26401 ggttgtcatc ttttttttga agacttctcg ttatagtcct tggtataggc gttaagattt
    26461 tgaatgaatc atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa
    26521 taattattac agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg
    26581 ttgatcgtat ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt
    26641 atgatgactt gaggcagatt gcagcgcttg ttcacaagac gggcaaggag ctaacagttg
    26701 cttgtaacgc tctgatgcac caagacatga tggatcgtat aaagccattt ttggacctta
    26761 tgaaggagat tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata
    26821 aacgagatgg ctacgacttt aagctgattt atgatacctc tgtttttgtt acctcaagcc
    26881 gtcaggttaa tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc
    26941 cctcggagga attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt
    27001 acggggcctc tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta
    27061 ccaaaattga tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc
    27121 ctgatagtca ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg
    27181 acattgatat gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc
    27241 tagatggtgt ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag
    27301 caaaggcttt gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag
    27361 aagtgcaagg gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc
    27421 ctaaaacagt caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc
    27481 atgacaagtt aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa
    27541 caacatgtca aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa
    27601 attaaaggtt gccattgatt atggtgctga tgcggttttt gttggtggac aggcctacgg
    27661 gctaagaagt cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc
    27721 tcacaagtat ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaatga
    27781 gcttggagca ggtgagtggt tccgccaatt gcgtgatatg gggcttgatg cggtcatcgt
    27841 ttcagacccg gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct
    27901 atcaactcaa gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct
    27961 aacgcgtgtc gtgctagcac gtgaggtcaa tatggcagaa ttagccgaga ttcgaaagcg
    28021 cacagaggtt gagattgagg ctttcgtgca tggtgccatg tgtatttcct attcagggcg
    28081 ctgtgttctc tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc
    28141 ctgccgctgg aagtatgatt tgtatgatat gccctttggc tcagagcgtc gttccttaaa
    28201 aggagagatt ccagaggaat actccatgtc ctcggttgac atgtgtatgc tggagcatat
    28261 ccctgatttg attgaaaatg gggttgatag cttgaaaatc gaagggcgca tgaagtctat
    28321 ccattatgtg tcaacagtga ccaattgcta taaggcggct gttgacgctt atatggaaag
    28381 tccagaagcc tttgccgcta ttaaagatga cttgattgac gagctttgga aggtggctca
    28441 gcgtgagcta gcgactggct tttattatca tacaccaact gaaaatgaac agctatttgg
    28501 tgcgcggcgt aagattccac aatacaaatt tgttggggag gtggtttcct ttgatgatga
    28561 cagcatgaca gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt
    28621 ttacggaccg ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg
    28681 caataaaatt gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc
    28741 tgtcaagcca ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa
    28801 ggacggaacc agtaagacca taagagccta gcaccactag actaagcaat aggatttgac
    28861 caattacctt tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta
    28921 ctgagtctat ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc
    28981 aatatctgct aaaaaaataa tggcagtcag gttttgattg gtatttttta agaccaattg
    29041 accggttagc tgatcgtatt ttttaatgtg cccagtgaag cttttggctt gatagatcac
    29101 atgaattgga atctccttga cctgtgcctc tttgatggtg gtaatgatct ggttggcctt
    29161 gaggttaacg ggagaagcct tggctttttt gggaggctga ttgtcaataa agccgatcaa
    29221 ggctgattgc agctgcttca tcattgattt catagctatt gtcctcaaac attgatagaa
    29281 tagtttgata gtattttacc ttaaactatg atttttaaaa agaatttact gttttgcatt
    29341 caatttttaa tattattttc gaatagatag atgaggagga aaatataatg tcagaattta
    29401 catttaagat tgaggagcat ttgctaaccc tgtcagaaag cgataagggg tggacaaaag
    29461 agctaaaccg cgttagtttc aatggagcag agccaaaatg ggatatccgc acctggagcc
    29521 ctgatcatac taagatgggc aagggcatta ccctaaccaa tgaagaattt aagacaattc
    29581 ttgatgcctt tcgtcgttaa gccttagctt agtcatcaat aacctcaatg tgagaagaac
    29641 cttttctaat gaacagtatc aaccatcagt tactttgttc ttgtaggaag gtttttttgt
    29701 tatctcttca agtgagtttt taagagcaag gtaaaagact atcgtctaga acccccttag
    29761 cattcatagc tgctaccgca acgataaaag ttaaaaaaca atctaactgg ggatctggta
    29821 tctagaaagc taatctagtc ctcttagagc ttttagtgac tgttagtcac tatctattgg
    29881 tgagaggagt atatcacaat gctccaatcg agccttggtt tgggtgtttt aagtccgaat
    29941 gctatgaact aaagtcatac cagacttgtg aagagcctat cactggtagt aatcactatc
    30001 tccactttta caatgatagc catctttaaa agcacatgaa aggccctgcc cctcctttaa
    30061 ggaggaacaa ggcttctgtt taatcattat gagattagta ttcgcttaat aggaagtcac
    30121 tcaagctcag cgtctatttt gagactgatg cttctgtcct agccttaggt tgctcatatt
    30181 ctgctctaaa atcatacgga ttgtcctgac ttgctttaga atagcatact tgttgagtct
    30241 aggtctcaag gattttgaat gactgacgtt gaaggtgttt agctcctgtt atcttggtat
    30301 aagaaggtat gaccttttgg taattggatt gtctattgta tgcttccaag atgatgactg
    30361 ggatgcttga ttgttaacta caagctgata gccttggtag aggttgtgtt ttaataaggg
    30421 cttaagagct attttttcct taatgtaagg cttgttggct ggtagctatc gagacttgga
    30481 ggtggtagag ggctagccta aggctttgac ttgaaacgat cggctagacc aataatcatg
    30541 aggatcagtc ctaaagcaaa gaaaatccat ttcaagctga ttaaggcata aagggtaaaa
    30601 attgcagctg agaggtaact aatgtattct tttttcataa aatgctccct atctttttac
    30661 actattgtag cataaaaatc agcttaaatg ctgctgagat caatgactgc tttatttaag
    30721 ctttcattgg cctagctaaa aaccgtttat cctagcagca tgtcatcatt gcaaacaaaa
    30781 aagattgaag aatcaagtct aagagatgat tcttcaatcc tagtatacag acaagctaag
    30841 gacatcactt caaaagtgag gcttttagag aagctaaagg caactaatga ctattagcta
    30901 ggcctagcta tggaagtaat ttgtcatagt gatcatgcca tctggataag tggcttaaga
    30961 tcatggccgc cgctaaagcc tattggctag cgctggctat agtcagcttt agacagctct
    31021 ttttaatcac tggtggccag tcgcttttta tggcttcatt gttgggaaca agagcacatc
    31081 gcgaattgtt gttgtattgg ttagcagcat acaaagacgg tcgataccga ttccaagtcc
    31141 acctgttggt ggcataccgt actcaagggc ttcaacgaag tcgtaatcaa tgccggttgc
    31201 ttcatcgtct ccaagctctt tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
    31261 tggatcgttt agctcggtaa aggcgttagc gtactctttg gtcatgataa agagctcaaa
    31321 gcggtctgtg aagcggctgt cctcaggatt tttcttagca agtggtgaga cctctacggg
    31381 gtgcccgtaa acaaaggttg gctgaatgag ggtgtcttcg acaaaggctt caaagaaggc
    31441 attaatgata tgaccaacgg aggtaaagtg cttctcaagt ggcacatgct tttcattagc
    31501 tagagccttt gcgtcttcaa aagtcatctc agaccagaaa tcaacaccag ctacctcctt
    31561 aatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
    31621 ataatcaatt ggcccttctc ccttgaccgc tttagcagca tgctgaatga ttccttcagt
    31681 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
    31741 tgggttatgt gtggcgtcca ttccttcatt acgaaagatc cgtccgatct catagacacg
    31801 ctccatgcca ccgacgataa ggcgcttgag atgtaactcc gttgcaatac gaagcaccat
    31861 gtcaatatct tgggcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
    31921 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcaagat aacgacgaat
    31981 ttcagaaatc atttttgaac gtgtgacgaa ccgctcaaag ctgctgcggt ttgaaatcaa
    32041 atccagatga cgtttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
    32101 tagcggacgt agagatttgg agaggtgggt tagttttgtc gccttgatag acagctcacc
    32161 catatcagta cgcataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttctt
    32221 gaaaatgtca tagttttcat caccaactga atccttgcga acgtagatct ggatttgccc
    32281 ttgacgatcc tgaagatgag caaagcccac ctttccttta ccacgcttgg tcatcagacg
    32341 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
    32401 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
    32461 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
    32521 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
    32581 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
    32641 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
    32701 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
    32761 atgatatttg acaaaaaact taaattgtga aaaaatatta atcgaaaaaa tcaaaaaact
    32821 ctcaacgcta aggctagtct ttgtgcagtt gagggttttt atcaggaaag gatcataaag
    32881 aaatggaaac ttatgatata cacgggaagc cttatcatcg aacgctgatg attatattgc
    32941 tgttggtggg aacctttgca ggggttttaa accaaacaag cttggggaca gctataccaa
    33001 cattgatgga aaactttaag gtacctttgt caacaactca gcaggcaacc acttggtttt
    33061 tgcttgctaa tggcattatg atccctgttt cggccttttt agcaacgcga ttttccacta
    33121 aaagactcta catgacagct tatgctattc ttgtgagtgg cttgttgcta gcagctctgg
    33181 ctccgactgc tcattgggga gtttttttaa cagcacgtat cgttcaggct tgtgcagtgg
    33241 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
    33301 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
    33361 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggatggcggg
    33421 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
    33481 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
    33541 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
    33601 atatggtgta cgtgatttta cctattttag tcggtattgg tgggatttac ctcttttcca
    33661 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
    33721 ttaccttgac aacaatagca attgccctaa cgatgatggc gatgattggt gttgagatga
    33781 tgttgccgct gtatctgcaa aatgtcagag acttatctcc attaaattcc ggaatggttt
    33841 tattgccggg ggctttgatt atggggctga tcagcccagt ttctggccgc atttatgaca
    33901 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
    33961 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
    34021 gaatgtttgg catatcaatg attttaatgc ctttaaccgc aagtgctatg aatgccttgc
    34081 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
    34141 ctattgttgt agcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
    34201 ctaaaatgct cctatccata caccctgagc aatatgctaa gaagcttcta gaagccaatt
    34261 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
    34321 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gcccctgatt agcgtgatta
    34381 gaacaaataa gctaaaggct tcacgccaag cacatgaaaa aacagctgtt tttgatagct
    34441 tttctgatta atgcgctctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
    34501 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgtgtct agaaaattgt
    34561 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
    34621 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
    34681 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
    34741 aatggaaaag tgctttccag attttgatat gtcgttgatc aatcaagcct atatccgttt
    34801 tcgccattat tctgacgttg ggtttccaag agtgatgtca ggtgagtgga cgacagaata
    34861 tttccgattt tggcggtgtc gggagacctt gcttgagttt ggctatcgtg acattgatca
    34921 gacaacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
    34981 tgatgaaatg cgcatgacgc ttgatttctt gaagtcaaaa aacgttccga tggggattat
    35041 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
    35101 tgttgatcct aagcgcgtga ttgtcagtca agcaacgggc tttcaaaagc cagaaaaaga
    35161 gatattcaat ctagcagcag agcagtttga catgaaccct gcgacaaccc tttatgtcgg
    35221 cgattcttac gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
    35281 taaccacaga ggtagaagct taaagcctgg gacaaggcct atctatgatg tggctattga
    35341 taactttgag caactgtttg gtgctgttaa ggttttgttt gatctgccag ataacaaggt
    35401 tatttttgat atcaatgaca agaaaaaccc ggtgctgcaa ttaggtctta acaatggttt
    35461 gatgatggcg gcagaacgct tgttagaaag taatatgagt attgataagg ttgttgtcct
    35521 gttgcgtttg aacaagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
    35581 gctattgatt gaaaagcatg ctatgtttaa ttggc
//
LOCUS       DARYSY010000019        34806 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYSY010000019 DARYSY010000000
VERSION     DARYSY010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34806
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            153..890
                     /locus_tag="TVR04_000835"
     CDS             153..890
                     /locus_tag="TVR04_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269539.1"
                     /translation="MPRFSKVIRYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKVGSKVLPKT
                     GGATDGLVGLAVGLDLLSVSGYLIYKNKKSGKYVLIALLTAGGATTAVSAVDVVRHLN
                     DVVMKTTVKGISFTYTPEERVDDYCYVGYIMTQENSPAPTPEPKPDPVLTPEPKPEPK
                     LDPVPTPEPKPEPVPTPDPEYFEAIPQ"
     gene            complement(1002..3188)
                     /locus_tag="TVR04_000836"
     CDS             complement(1002..3188)
                     /locus_tag="TVR04_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1269540.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIMIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            3336..4499
                     /locus_tag="TVR04_000837"
     CDS             3336..4499
                     /locus_tag="TVR04_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1269541.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDNQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGASAPDTFTILENGVSYQVFLNDGLMTGIFLDQHEVRRGLVEGLALGKSVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSIELSKAHFIQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARHKKQTFSVSKDYHQLIAEALDLLAPKGTMIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
     gene            4496..5176
                     /locus_tag="TVR04_000838"
     CDS             4496..5176
                     /locus_tag="TVR04_000838"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1269542.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSREGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            5289..6455
                     /gene="aroC"
                     /locus_tag="TVR04_000839"
     CDS             5289..6455
                     /gene="aroC"
                     /locus_tag="TVR04_000839"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1269543.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAISFADIKQAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETIIYGLPAGLGSYVQWDRKLDAKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            6516..6857
                     /locus_tag="TVR04_000840"
     CDS             6516..6857
                     /locus_tag="TVR04_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1269544.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            7051..8403
                     /gene="gorA"
                     /locus_tag="TVR04_000841"
     CDS             7051..8403
                     /gene="gorA"
                     /locus_tag="TVR04_000841"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1269545.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKRGYIATDAYENTSVEGIYAVGDVNGKLALTPVAVAAGRRLAERLFHHKANEKL
                     DYDKVATVVFSHPPIGSIGLTEEAAIQAYGQEAVRVYQSQFTSMYTAITSHRQPCLMK
                     LVVAGEEETVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(8474..8914)
                     /locus_tag="TVR04_000842"
     CDS             complement(8474..8914)
                     /locus_tag="TVR04_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269546.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            9154..10296
                     /locus_tag="TVR04_000843"
     CDS             9154..10296
                     /locus_tag="TVR04_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1269547.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVNVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKAGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            10298..11512
                     /gene="thiI"
                     /locus_tag="TVR04_000844"
     CDS             10298..11512
                     /gene="thiI"
                     /locus_tag="TVR04_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1269548.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVNGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(11636..11878)
                     /locus_tag="TVR04_000845"
     CDS             complement(11636..11878)
                     /locus_tag="TVR04_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269549.1"
                     /translation="MISCTLLASLLLTGCHPLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTIGLTNEEAMKQYEEVLSDEVIQYFSS"
     gene            complement(12213..13262)
                     /locus_tag="TVR04_000846"
     CDS             complement(12213..13262)
                     /locus_tag="TVR04_000846"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1269550.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHGHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(13786..14127)
                     /locus_tag="TVR04_000847"
     CDS             complement(13786..14127)
                     /locus_tag="TVR04_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269551.1"
                     /translation="MTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGDVEYLL
                     TPKQEGYDDLVSFLKSLGISHFDATLYSDSMAGQDYKKLLADFKTKTSREVISAVMSE
                     LAKFYNDYSPF"
     gene            complement(14625..14976)
                     /gene="ssrA"
                     /locus_tag="TVR04_000848"
     tmRNA           complement(14625..14976)
                     /gene="ssrA"
                     /locus_tag="TVR04_000848"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            15067..15678
                     /locus_tag="TVR04_000849"
     CDS             15067..15678
                     /locus_tag="TVR04_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1269552.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLETPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(15725..16519)
                     /locus_tag="TVR04_000850"
     CDS             complement(15725..16519)
                     /locus_tag="TVR04_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269553.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(16529..17227)
                     /locus_tag="TVR04_000851"
     CDS             complement(16529..17227)
                     /locus_tag="TVR04_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269554.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(17227..17598)
                     /locus_tag="TVR04_000852"
     CDS             complement(17227..17598)
                     /locus_tag="TVR04_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1269555.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELEREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            17840..20950
                     /locus_tag="TVR04_000853"
     CDS             17840..20950
                     /locus_tag="TVR04_000853"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1269556.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGEL
                     DLDTLVQYLEGIAVIVPFRQSLSDLGLPFDYFIGIDEASDLSKIGSTERLIPFRTVRY
                     FDDTETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLRERQLWKEPYQSRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVENFLCSIPEKYQKISFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVESHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            21030..22043
                     /gene="pfkA"
                     /locus_tag="TVR04_000854"
     CDS             21030..22043
                     /gene="pfkA"
                     /locus_tag="TVR04_000854"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1269557.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            22105..23607
                     /gene="pyk"
                     /locus_tag="TVR04_000855"
     CDS             22105..23607
                     /gene="pyk"
                     /locus_tag="TVR04_000855"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1269558.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDVIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            23736..24293
                     /gene="lepB"
                     /locus_tag="TVR04_000856"
     CDS             23736..24293
                     /gene="lepB"
                     /locus_tag="TVR04_000856"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1269559.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNRAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            24470..26281
                     /gene="glmS"
                     /locus_tag="TVR04_000857"
     CDS             24470..26281
                     /gene="glmS"
                     /locus_tag="TVR04_000857"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1269560.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQHLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIERQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLERLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANELGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQELLATTRNAFYIGRGNDYYIAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEDLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            26465..26800
                     /locus_tag="TVR04_000858"
     CDS             26465..26800
                     /locus_tag="TVR04_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1269561.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTPGEEEPEEDGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            26907..27548
                     /locus_tag="TVR04_000859"
     CDS             26907..27548
                     /locus_tag="TVR04_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1269562.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            27558..28187
                     /locus_tag="TVR04_000860"
     CDS             27558..28187
                     /locus_tag="TVR04_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1269563.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYSLSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDPELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            28204..29040
                     /locus_tag="TVR04_000861"
     CDS             28204..29040
                     /locus_tag="TVR04_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1269564.1"
                     /translation="MTLKKTLLAALFAATATLLVACGASNKQTSSDGWKSYKEKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGIKVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVAADQL
                     RS"
     gene            complement(29157..30395)
                     /locus_tag="TVR04_000862"
     CDS             complement(29157..30395)
                     /locus_tag="TVR04_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1269565.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVAYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSKQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPEDDNCEHVYKKLYKNEKIMLSQIPDYQELIAETFTFIDRNGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSITIKKHYHIKRIS"
     gene            complement(30498..31832)
                     /locus_tag="TVR04_000863"
     CDS             complement(30498..31832)
                     /locus_tag="TVR04_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1269566.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGVYLTSRLGLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLASLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGVSSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSTLEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVVM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(31961..32047)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            32312..34603
                     /gene="pcrA"
                     /locus_tag="TVR04_000864"
     CDS             32312..34603
                     /gene="pcrA"
                     /locus_tag="TVR04_000864"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1269567.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQEQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT        10139 a         6385 c         7923 g        10359 t
ORIGIN      
        1 gtcaatattt attgataata gttgatataa tattttcata tgattcttat gaatctgaca
       61 tttttgataa caatattcat aagcttgaca tgataggaga tgccttttta gtcattattt
      121 ttagttgaca aaacattaag gagatagtta tgatgccgcg tttttctaaa gtgattcgat
      181 acatgggtgc tacaacgatg ttgggtctat ctttgctagc agctaatgtc aatgccaaca
      241 ctaatgctga tacggtaacg gtagatttga cctatacggc ctattctaat ctgacaaatg
      301 aacaaaaagc aggcattcaa aaaggcactc caaatgaagt acctatccaa gataaattgc
      361 attacgttct tgtttacgac aaaagctgtg gagtgacagc atctccaaaa ggaatgatgt
      421 ctacccctaa ggttggctct aaggtcttgc ctaaaacggg tggtgcaaca gatggtctgg
      481 ttggtttggc agtagggcta gatttactaa gtgtttcagg ctatcttatt tacaaaaata
      541 agaaaagtgg caaatatgtg ctgattgcct tgttaacagc tggtggtgcg acaacggctg
      601 ttagtgcagt tgatgtggta cgtcatctca atgatgtcgt catgaaaact acggttaagg
      661 ggataagttt tacttacact ccagaagaaa gggttgatga ctactgttat gtgggttata
      721 ttatgacgca agaaaatagc ccagcaccga cacccgaacc taagccagat cctgtgctaa
      781 caccagaacc gaagcctgag cctaagctag atcctgtgcc aacaccagaa ccgaagcctg
      841 agcctgtacc gacaccagat ccagaatact ttgaggccat tcctcaataa aagtgtcaga
      901 actaaaaagc cctcattaag ttgtaacgct taatgaaggc tttttgcttg cttttcgttt
      961 tctacgagag cgatcctagt gaggcttgct ttagacatcc actactgact ttgttcctta
     1021 acggattctt ctttagggtc agaagacgaa gtagattcag gtttttcggc ttctttagga
     1081 tttaactcca gataagaagg tgctttaaag agcttttgag ttgatttgtt gccattttta
     1141 ctataaatgc tggttgaatg tgatcctaat ttctctgata tctctttgag ttgttttagc
     1201 tgcttggtat aaatgaaggt tgttgggtca acaggtttca gaccattatc ggtatcaaag
     1261 cgtagtaagt ctcctgtttg gatagcgtca ctagctgcta gctgctgagc aacggctgct
     1321 cgtatttctt tgaccttagc cattgtcatc tcatcagggt ttgtaatttc caagcctgtt
     1381 tgagtgttat aaaggcgacc gctatagcta gtgtagtctg gcgtgatata agttccagag
     1441 gttctctgtg ctaccatttg actattttgt ggcgacaaga gatcctgtcc tagttgaacc
     1501 atcttgctgg tatcaatgcc caagatatgc agtaaggttg gtaaggaatc aatttctccg
     1561 ccaaaggttt ctttgatccc gccattggta tagcctggaa tatggatcat atatggtaca
     1621 cgctggagca ttgcattgtc atattcggac caagtttcag ggtctttacc cagtaattct
     1681 gccaagctga catttctgga attagaaata ccgtagtggt caccatatag aacaaagata
     1741 gaattgtcat aaagtcctgt cgccttgaga taatcaaaaa atgatttcaa ggctgaatcc
     1801 agatagttag ctgtagcaaa ataaccattg atggtttcat catcggtttt ggctagtgga
     1861 aagccctctt cactgctttc gcctctaagg ctggtgtaag ggtagtggtt gctgacggta
     1921 ataaacttag tgtagaaggg ctgttgaagc tgttcaaggt acttgataga atctctaaac
     1981 atgtatttgt catttaggcc atactggaaa gagtttttat cagtctgttt tgaaaaatag
     2041 cttgaatcaa aaaagtaatg atagccccat tgcttataag cattattgcg attccagaag
     2101 gttcctacat tcccatgaaa gacagcacta gtatagccgc cattttgtgc taggattgat
     2161 ggtgtggcga attgcgtgtt ttcgccgcca taatttacca taaaagaacc actgtttaag
     2221 ccaaataatg aattttccat catggtctct gcatcagacg tttttccagc cttgacctga
     2281 tggaaaaagt tagagaaggc tagtgtggca ttggagtggt agagggaatt aataaaaggt
     2341 gtgacctcat agtccttgtc gtcatccttg agcttgtaat caataagaaa ttgttggaag
     2401 ctttccaagt ggatcataat gacatttttt cccttaccga ttccaaaata ttgaggatca
     2461 ggtgcggcgt agtggttctt gacatattgc ttaacatcga ctaattcttc agcggttgct
     2521 ccgttacgct ctttttgtgc ttgataggtc tggtttccgc tgtaaatggt aaaagcaggc
     2581 aatccaagcg ctctaacgat ataggtattt gaaaatcctc tagtcagaag ctccggacgg
     2641 tcaatctctg caagaaacag attaacagat aagagcaagc aagacagtgc tgtaacagca
     2701 aaggaagccc gcttgttaaa aggacgtggg tcttttttga tggtcttagt gactgataaa
     2761 ctaatcagaa tgataaaatc aaggacgtaa acaatatccc aaatgcgcaa aaggtttaaa
     2821 gcagagtctc ctagaccagc agaaacctta ctactggcta gcatggcact aaccgtaatg
     2881 aaatctgaaa actctcggta ataaatagaa tttgatatta acaagaggtt aaggataata
     2941 tagacgatcc aagagctgat ataaaaggcc ctagtattct tgatataaag ggtaaatccc
     3001 aatagtaaca aagctagagg gattgggtta ataattgtta gaaagacctg ataggcattt
     3061 cccaaatcta gtgaaaagtc agcatggtaa gcccataggg tttttatcca aaagcagaag
     3121 agaagcgtta gcacaaagcc taatcttgta ttgataaagc ttgtgataaa tgttttaaaa
     3181 ttcttcacag taagaacttc cttatcattt tttcctaaaa gatataatct ccaaataaaa
     3241 tctcagatta aattatacca aaaatatgga gctaatgctt gcaataagtt taaatctagt
     3301 atgatttttt aatagttttt gttataatag aaactatgaa taaggtctgt attaatcccc
     3361 ttgttgaacg caagatagca gcagggatac aattactaga tgaaaaggat tttgatggca
     3421 ccatttggga caaccagtta gtgcagcttg tgaattcatc tcatcagctc atcggcacag
     3481 cttacctttc aaagcaacat aagggagtag gctggtatct aggaaggtct gttaagaaat
     3541 tgtcggtttc ttattttgtg accttattta agacagctaa gaagaaaaga gagcattttg
     3601 ccgcgtctga atggacaaat gcttaccgtc tttttaacca agacggtgat gattttggag
     3661 gactaaccat agacctctat aaggactttg ctttattttc ttggtataat gtctttgttt
     3721 atcaagaaaa ggagcttatt attcaggctt ttcgagaggt ttttcctgag gtcaggggag
     3781 cttatgaaaa gattcgcttt aagggaccag ataaggagac ggctcatttg tatggcgcgt
     3841 ctgctcctga tacctttact attttagaaa atggtgtatc ctatcaggta tttttaaatg
     3901 atggcttgat gactgggatc tttcttgatc agcatgaggt tagacgaggt ctggtggagg
     3961 gcttagcact tggaaagtct gttttaaacc tgttttcata tacggcagct ttttctgtag
     4021 ctgcggcaat gggcggtgca gttgagacaa cctctgttga tttggcaaag cgctccatag
     4081 agttatcaaa ggctcatttt attcaaaatc agttggacct atccagtcat cagctggtcg
     4141 ttatggacgt ttttgactat tttaagtatg ctaagcgaaa gcagctttct tttgatctta
     4201 ttatcattga tccaccaagc tttgctagac acaaaaagca gacgttttcg gtgagcaagg
     4261 actaccatca attaatcgct gaggctctag acctattggc ccccaaggga acaatgatcg
     4321 cttcaacaaa tgctgccaat atgactgtta accagtttaa aaagcaaatt atcaaaggat
     4381 tgggaggcag gccattagct cagatgacac ttgagcagct tccaagtgat tttactatca
     4441 ataaagcaga tgaaagaagt aattatttaa aggtatttac tataagggta cgagaatgaa
     4501 aattgtagca ccagtcatgc caagaaatgt tgaagaggct caatctatcg acgtttctaa
     4561 atatcaagat gttaatttaa tcgagtggcg agcagacttt cttcctaagg aggatattgt
     4621 ttctgtagcg ccagctattt ttgaaaaatt tgcaggtaga gagattattt ttacccttcg
     4681 tacaagtcga gaaggagggc atattacact ttctgatcag gaatacgttg atttgatcaa
     4741 ggagatcaat gcgatttata atcctgacta tattgacttt gaatacttta gtcacaaggc
     4801 tgtctttcat gaaatgcttg actttccgaa tcttgtcttg tcttatcaca attttgatga
     4861 gacgcctgaa aatctgatgg aggctttttc ggagatgact aagctagctc ctcgcgttgt
     4921 caagattgct gtcatgccgc agagcgagca ggacgttttg gatttgatga attataccag
     4981 aggctttaaa acacttaacc cagagcagga atttgcaacc atgtcaatgg gaaagctagg
     5041 cagactatca cgcttggcag gtgatgttgt agggtcctcg tggacttttg tgtccttaga
     5101 tcaagccagt gcaccagggc aggtttcctt ggctgatatg aaaaggattc ttcatgtttt
     5161 ggaatctgag gattgataag atacggtaac agacattatt ctcttggata gcttagaata
     5221 atgtctttta gttgtctaga ggagggcagg tttgcttttt atgtctatga ttgataaatg
     5281 gaggaataat gaggtattta acagcaggtg agtcacatgg acaagctttg acggccatta
     5341 tagagggaat tcctgcaggc ttagcattat cagctgagct tattaacaag gaactgaagc
     5401 gtcggcaggg gggatatggt cgtggcgcac gcatgcgcat tgaatcagat cgtgtgcata
     5461 tctcttcagg tgttcgtcat ggcaaaacaa caggagcacc aattacttta accattcaaa
     5521 acaaggacca tcaaaaatgg ctagacatta tggctgttga ggctgttgaa gagcaaatca
     5581 agttcaagcg taaaatcact cgtccacgcc ctggtcatgc tgacttggtt ggggggatca
     5641 aatatcgttt tgatgattta agaaatgcgc ttgagcgctc ctctgccaga gaaacagcga
     5701 tgcgtgtggc cgttggtgca attgctaagg caatccttac tgagcttggg atcgaaactg
     5761 ctaatcatgt cctagttttt ggtggtatcg aggtagctgt gcctgaggcg atatcctttg
     5821 cagatatcaa acaagcagca gaggcttctg atttatctat tgtcaatcct aagcaggagg
     5881 cgactatcaa ggctcatatt gatcaagtca aaaaagaggg ggatacgctt ggcggtatta
     5941 ttgaaacaat catttatggc ttaccagcag gcttaggctc atacgttcaa tgggatcgca
     6001 aattagatgc caaaatcgcg cagactgtcc tgtctatcaa cgcctttaaa ggggtcgaat
     6061 ttggtatggg ctttgacatg ggttaccaaa aaggctcgca ggtcatggac gacatcattt
     6121 ggcatgagac aagcggctac agtcgtcgaa caaaccgact aggtggcttt gaggcaggta
     6181 tgactactgg tcagcctatt gttgtcaaag gggtgatgaa gccgattccc accctctaca
     6241 agcccctaat gtctgtggat actgagacgc acgagcctta caaggctact gttgagcgtt
     6301 ctgatcctac ggctctgccg gctgccggtg tcgtgatgga aaatgttgta gcaactgtca
     6361 tcacaaaaga gattttggaa caatttccat cagacaatat gaccgattta aagcaggctt
     6421 tttttgccta tcgtgactat gttcatcatt tttaagcgac aaatggcttg atattgtgat
     6481 atgataagga taataaatga taaaaggaga tccagatgtc ccaagatatt tatgattatg
     6541 ccaataagct tgagcgagct gttcgtgcgc tcccagagta tcgcaaggcc ttggaagcca
     6601 gagaagagat taaggcagat gaggctgcca gtcagctatt tgatgagttt gttgctgtgc
     6661 aagaaaaatt gcaaggactc atgcagaccg gtcagctgcc aacagagaca gagcaggcag
     6721 atattcaggc tctcagccaa aaaattgagg ccaatgacct attaaaaggg tattttaacg
     6781 ctcagcaggc tctttccgtc tatgttaatg atattgaacg gattgtattt gcaccattga
     6841 aggatttggc caagtagagc taagctggct taggattaag agaagaaagg attgttgatg
     6901 cttatcacaa tctttttttg tcgtagcagg gatttgagac acaagttatt ttatgttata
     6961 gtcaaatgac agtagattaa aataaagcaa taatgatagc ttaataacaa atctattgag
     7021 gcaagcatta agagtaaagg tggtaaatga atggcaattc agtatgatta tattgtgatt
     7081 ggtggtggga gcgctgggat tgcctcggcg aatcgtgcag caatgtacgg tgctaaggtc
     7141 ctattagctg agggcaaggc tattggagga acctgtgtta atttgggctg tgtgcctaaa
     7201 aaggtcatgt ggtatggcgc acaggtagca gaaacgattc atacctatgc gaaggattac
     7261 gggtttacgg tgttagagga taggtttgat tttaaaacct taaaaagcaa tcgtcaggcc
     7321 tatattgacc gtattcatgc ctcctatgag aagggctttg agcataatgg ggttgaccgt
     7381 atctatgatt atgcgcgatt tattgatcag catacggttg acattgcagg taagacctat
     7441 acagcccctc atattttaat cgctactggt ggtcagccta tttttcctga cattgaagga
     7501 gctgagctgg ggattagctc agatggcttc tttgccttag atgatattcc aaaacgaaca
     7561 gcggttgtcg gtgctggcta tatcgctgtt gagattgcag gagtgctcaa tgccttaggc
     7621 tctcagacgg atttgctggt tcgctatgac aggccactga ggacctttga tcaggatatt
     7681 attcaggttc tggtcgatga gatgaaggta tctggaccaa ggctgcatac caatgccgat
     7741 gttactaagg ttaccaaggc taatgatggc tctcttcaag tgcatttgtc cgacggtcgt
     7801 aggcttgaag tggaccaagt gatttgggca attggccgca agccaaatgt gacaggcttt
     7861 ggcttggagc atacaggagt tgagctggat aagaggggct atattgctac tgatgcttat
     7921 gaaaacacgt ctgtcgaggg catctatgct gttggtgatg tgaatggaaa gcttgctttg
     7981 accccagttg ctgtcgcagc aggtcgtcgc ttagcagagc gtttgtttca tcataaggcc
     8041 aatgaaaagc ttgattatga taaggttgcg acggttgtct ttagccatcc gccaattggt
     8101 tcgatcggct taacagaaga ggcagctatt caagcctatg ggcaggaggc tgttcgtgtc
     8161 tatcaatcac aatttacgtc tatgtataca gctattacca gtcaccgcca gccctgtcta
     8221 atgaaattgg ttgttgcagg agaagaagag actgtcgttg gtctgcatgg aattggttat
     8281 ggcgtcgatg agatgattca aggctttgct gttgccatta aaatgggggc tactaaggct
     8341 gattttgaca atactgttgc cattcatccc acaggtgctg aagagtttgt taccatgaga
     8401 taatagcaca tgataaaaca cgataacatg acagttcaga gtttatctga attgtctgtt
     8461 atcgtgtttt gtgttatgga ttgcttgtac tgttaggagc tggctcatta gctgtgggtt
     8521 gattagcagc cggtgcttcc gtttcggtat tctgttgttt ttctgtatcc ttagtagcag
     8581 gatcagctga gctaggagta gtatgtgtcg cctgagtacc gctagaatca gaattagttt
     8641 ctgtcttgtc agtctcttcc ttatttgagt gtgacgactc cttttcaata attttcacaa
     8701 tcgttgatgt tgatgacgga gaggaatcgc ttttgggttg ctcatttgat ggttgtagag
     8761 ctcgattaat agtgattgtc gctacaacaa tactcagaac actaccaact aaggcaatgg
     8821 ttttttgaag ggcggtaaag ccagttttaa tatgctttgt gggaatactt gctgattttt
     8881 taggcttttg ttgacgtgaa taatgtgatg acatgagaat atctccttta acgagtcata
     8941 ggctagctaa agtcaaatgc tttaggtctt taatggctaa caggcatttc agacttagct
     9001 ctatcatcta ccagtataat ctagaacaaa aatcaagtca acggtttacc ttattgtcta
     9061 ggatagagtt gtcctatcct gcaaaaagat ctattttttc atttcatcaa atttgtgata
     9121 caataaagta ttgaataaaa atgaaggtga cacatgattt attttgataa tgcagccact
     9181 accaagcctt acgaagaggc acttaaaacg tatcaggaag tggccagtaa gatttacggc
     9241 aatccctcta gtctccatca gctaggagcc aatgccagtc gtatattgga ggcttcgcgc
     9301 aggcaaatag cggccttact tgatgtagag gccaaagaga ttttctttac ctctggcgga
     9361 acggaaagcg acaattgggc tatcaagggg attgcctttg aaaaatctca ctttggtaag
     9421 cacatcattg tctcagccat tgagcaccca gctgtcagag aaagcgccaa atggctagaa
     9481 agtcaaggct ttgagctgtc ttatgctcct gtcacagata agggagttgt taatgtcaaa
     9541 aagctagctg ccttaatccg aaaagatacc atattagttt ccattatggc ggttaacaat
     9601 gagattgggt caattcagcc gattgcagcc atatcagagc ttttggctga taagcccacc
     9661 attacctttc atgtcgatgc tgttcaggct attgggaagc ttcctgttga ggcttactta
     9721 accgcgcgtg ttgacttagc ttctttttct ggtcataaat ttcatgctgt tcgtggtgtt
     9781 ggctttcttt ataaaaaatc aggaaagcga atcactccct tattggtcgg tggcggtcaa
     9841 gaagatgagc tacgctcgac aactgaaaac gtggcagcta ttgcaagtat ggccaaggct
     9901 ttaaggatca tcacagaaag acaggataga tctcaagcaa ggatagcagc catgaaaaag
     9961 gttatttatc aagccttgca ggcctatgag gataccattc tcttttctga gatagatgat
    10021 tttgctcctc atattctgac ctttggtata aagggcgttc gtggagaggt tattgtgcac
    10081 gcatttgaaa agcatgagat ttatatatca acaacgagtg cctgctcatc aaaggctgga
    10141 aagccggcag gaaccttagt ctcaatggga attccagcag cattggctca aacagcagtc
    10201 cgtatcagcc tagatgatga taatgatatg ggacaggttg agcaattttt aacgattttt
    10261 aaacagattt atgaaaaaac acaaaaggtt agataatatg aaatattcag aaataatggt
    10321 tcgtcatggg gagttatcga ccaagggaaa aaaccgtatg cggtttatta atcggctaaa
    10381 agctaatatt caagatgttc tttctgccta ttctgaggtg acagtcagat caactcgaga
    10441 caggacccat gttttactta atggtgcaga tgataggtct gtgattgaag ccttaaagcc
    10501 ggtgtttggt attcagggct tatctcctgt ctataaagtt gaaaaaagtg tccctgtact
    10561 gatagcagca gttcaggaga ttatgagctc cttgtatcgc gaagggctaa cctttaaaat
    10621 atccagcaag cgtagtgacc atcagtttga gctagatagc cgcgacctca accacacctt
    10681 aggagcagcc gtctttgagg ctttgccgca tatcaaggca cagatgaaaa atcctgatgt
    10741 taccctaaag gtcgaaattc gtgatgaggc tgcttatctg tctcacgaag atataaaggg
    10801 agctggaggg ctgccggttg gagcttcagg aaagggaatg ctgatgctat caggtggtat
    10861 tgattcaccg gttgcgggct atctatccct gaaacgaggt gttgagattg aggcagtgca
    10921 ttttgcaagc ccaccctata ccagtcctgg tgcgctaaga aaagccaagg atctaacgca
    10981 gcgcttaaca cgttttggag gtaatataca gtttatcgag gttccattta ccgagattca
    11041 agaggagatc aagcataagg cacccgaagc ctatttgatg acacttacta gacgcttcat
    11101 gctgcggatc acagatgcta ttcgtgagaa gcgaaaggct ttagtgatta ttaacggtga
    11161 aagcttagga caggttgcaa gccagacctt agagagcatg caggctatta atgcagtcac
    11221 ttcaactccg attatcagac cagttgtggc aatggataag ctagaaatta ttgacatcgc
    11281 tcagcaaatt gatacctttg atatttctat tcagcccttt gaggactgct gtaccatttt
    11341 tgctcccgat cgtcccaaaa ccaatcccaa gctagcaaat gttgaacgat atgagtctcg
    11401 ctttgatgtc aacggattgg tcgagcgagc agtggcaggg atcagagtaa ctgagatcac
    11461 tcctgaaatc gaaactgaca gcttatcaac gcttattgag gaattgttgt aggaggtgcg
    11521 cacctagccc tataacataa gcagtctatc taaacagtca aaaaaagcca gacctattag
    11581 ttattaaagg ctctggcttt tgtttttagc tgattttgct agcaaatcct cttatttagc
    11641 tgctaaaata ctggataacc tcatcagaaa ggacctcttc gtattgtttc atagcctctt
    11701 cattagttaa gcctatcgtt tgtaggtagg ctttcaagga ttcggcaatg ccatgcctgg
    11761 tcaaatcctc taccgtaacc gcttgaatag gcttttcctg aacagcctca gctagctgca
    11821 aagacaatgg gtgacagcca gttaataaga gactggctaa tagtgtacaa cttatcaata
    11881 tagatttttt catatatttc cctcctttca tgaaaattat atgaaaacaa ccataaattg
    11941 taaactattt agatttattt ttagtataat gttcgtgttt tatgttcgaa aaatgatttt
    12001 tttattaaag taaaaaataa tgtttggttt ttatattagg tatctacttg cctattttaa
    12061 aagaacacta aatagaggga tatcggtctc aaatgtgaca agagcttaaa gagttcatga
    12121 caagctttaa ccaatgacag tgagctaata gggctattgt tagacgaaaa aacagaccaa
    12181 taagcacttg gtctgttcct aatgatgact ggttagctca gtttctgcca tatgtccttg
    12241 ccactggaaa gcgtaaataa gcctaatact tgagcgccaa tgttttctcc ttctattttc
    12301 ttggcagaaa tggcgacatg tccatgagca ttaatgccga caaaatattt tttcatacca
    12361 atagacgcat tagcatctga gtctgtgaca tagatggcct caaggtttcc ttcagcatta
    12421 aaatcagctc cccacaagtt aatcacatgg ctaatgctaa cattggcgta ggtatgtgat
    12481 aaagcaaggg ctcttccttc agtcagttct tgcttgataa tggtgctgat gtcatttagt
    12541 cctttatttt ttaaatcatg acgagctgtc aagagcgttg tctgatctcc tctggtgaaa
    12601 acagcatcga aaataccacc tcgtttgtcc ttgtcctgat aaggtcgatt gacatcagta
    12661 gactgtgttt taaacacatt taagtagtaa ccattgataa acatgtctag aacaagatca
    12721 ggcataaccc cgagttgacg tgctgataga tttggaaagg ctttatctct aaaataatta
    12781 aaaagctgac tattggtttg actgtccttg gtatcgatag cagctttcaa atcaaatagc
    12841 tcttggttgt taaaaatgat tttttgcttt tcagggtgtt tacttaaata ggcttcaatc
    12901 tctgttttat tttgatcaaa ccaccaatgc agcatattac ctgccgttgc tgcgccacac
    12961 aagagattat ccttcccatc gaaggccttg gtgatatcgt accagccttg atgagcaaga
    13021 tatggcgcat ggatcacatc ttcgttatta tatcgaaact gctcgggtgt tagtggtgta
    13081 acacctttgg tccatacaga agtgatctga tgtggtactt ctttggcata agcttccgta
    13141 gcattccttt ggtaatcgtc agcataagta atgtttgaac tcgccaggct aaaaatagct
    13201 atagcagtta agagaccagc tgataaggag tgaggtttat ttggataagc tattgttttc
    13261 atataaccct ttcttgttat ggtgatatta tcattaaata atgttaatga catttatata
    13321 ttatcacaat attttgttga gacaatgctt ttgataagct ttatttatta gtaaatagtg
    13381 atgagatagt agagatgctg gcagactgga tctctataat ggatatttca gcttggttta
    13441 tgttagcgtt acctatttta ccaatgatga taccgtttgg tattgttggt gtcatgcctt
    13501 agacatgagc tgttattatt gagaccacta ataagagcta gtgtaggctt tgatgttatt
    13561 gggattcttg cacaatctta gccaagctta gtcagcaaat cagggcatta gctaggatag
    13621 taaggacaat ggtgcagtta ttacttgatt agctaggcgg acaatttagg agatggcctg
    13681 gttactaagc agattgacaa agagaagcat agctctatca agttaaaacc gctcggaagg
    13741 ttgtccgagc ggttttgatc tatgataact tattatgtta tttaattaaa aaggggaata
    13801 gtcattgtaa aatttagcta attcagacat caccgcagaa ataacttcac gagaagtctt
    13861 agttttaaag tcagctagta attttttgta atcttgacca gccatagagt ctgaataaag
    13921 agttgcgtca aaatggctga tgcctaggct ctttaagaat gacactaaat cgtcgtatcc
    13981 ttcttgctta ggcgttaaaa gatattccac gtcaccataa acatagtcat cagctttact
    14041 gatgtgagtt gaagccgtta ggcagactcc tgccaaagct agggcagcca ttgtagaaac
    14101 cataaatttc ttacaagctt gtgtcatata agtgtcctcc atttccaacg gttcctttgt
    14161 ccgtcgttat ttttgtgata ttttccttat cacaatgtta gtttaactca aaatctgtca
    14221 aaagtcaaat gtttttgtaa ttaaattaat aaagtgtttt taaaaaatta aagaaatgta
    14281 gcttttggaa taattaaatt attgaaattt tgtaaagaag cacaatatca taacagatga
    14341 tatctataaa gcagcagtaa atgatgtcta tatgacaggc aatacagggc aattatccga
    14401 aaaaatttga taatatgctg tcaatgaagc aagtaaaaga agtattataa aaaaataaat
    14461 ataagattag ctaaagagaa aattcaagct gttcttaaag gattttttgg cctttttttt
    14521 gctatcactt tcatagaaac ttacggtaac ccacgaacag gacaaaaaga aaaaaccttg
    14581 atttaacaag gttttagtaa gttatggtaa cttacggtaa gtattgatgg agctggtggg
    14641 agtcgaaccc acgtccaaac acctgctaac ctatttatct acaaccatag gttatgtctt
    14701 actttaacag accaaggaca cataactcaa gccatcagcc tgcgagtcta gggttctctt
    14761 tttaggtgac tagacaatca cctaaacgta gcttgctgtt ttgagacctc taataagaca
    14821 caagcaatcc tatagaagtc acgccggctg gtttttaggc agctaaagcg taagaatatg
    14881 tattattttt tgcagttata tttaactggc atttttacat ctgccgatga gttgcaaaat
    14941 aggcctcata atgcctgtcg aatccgtaac aaccccataa aaaggcgtat gagatactta
    15001 cggatgctag tatagcaaaa tttttttaaa atggcaaaaa aatagcgctt atggtatgat
    15061 gaagctatga gaaataatga gttgaagcct tatgtgatat ggcaaaaagt gattaagcta
    15121 ttaggaagtc tggctttagt cggatctttt ttgctagcct tttggtttta caggcttggc
    15181 attttaaatg acagcaatgc actcaaggat cttgttcata gtcacaaggt ttttggcccc
    15241 cttgtttttg tcggtgtgca aattgttcag attgtttttc ctattattcc aggtggtatg
    15301 acaactattg caggcttttt gatttttggt cctttgctgg gttttcttta taactatgtt
    15361 ggtatcttca ttggtagtgt gattctgttt ttacttgtga agacctatgg taggcgcttt
    15421 attttactgt ttatagagga acagaccttt tacaagtatg agagaaaatt agagacgcca
    15481 tattatgaga gattgtttat tctctgtatg ctttctccga tttcaccagc agatattatg
    15541 gtcatgatta ctgggctgac agagatgtcg ttgaagcgtt ttgtgaccat tattttaatc
    15601 acgaagccac tatcaattat tggctacagc tatcttttta tctttggaaa ggatttgatc
    15661 ctatggtttt tccattaaaa aagtctaggc attgcctgat aagcagtggc tagacttttt
    15721 gttatcattg gatattaagc ttgtttttga tgatgaagtg agtagcaacg taaaggataa
    15781 tgccttcaac tagttgctct atgtttaaaa tagatatggc tgtatgatca ccgaaataga
    15841 gtagcgagtc tgagctattt gggttgacgg tgaaaaacgc atcatttaaa taagtcatga
    15901 cgacaataat gataataact aaaatgaaat aggcacaaaa tgccatcaaa ccacgacgat
    15961 ttgaaaatag ctgaccaatt gagattgcta gataaatcaa tagtatactt gttatggttg
    16021 acaaaagcat gtagatgagg atagaagcat tttcgactaa gttttctggc ttcataattg
    16081 tctttagcac ctttagtaga taggtaaagt caactgttgg tgctattaaa ataaagatac
    16141 cgattaatag gttaataccg ttaaaaatac tgcaaacaaa ggacgctaat agcttagaca
    16201 gaataatttg atgtgctgtt accggcagtg tcagtgttaa gtatccctcg cgcccaaaga
    16261 catttttgtt aaagcgatta atgatgatta atagcgttga taagaatgat ccggcaatca
    16321 gagaaccaaa cgttaatgag agtgtgagag gaaccatttt gtttgccaga cttgttgtta
    16381 aaccaacctc gtcaggattg tttgtaagcg tattgatggt aaaagaaagg actatcgcga
    16441 tagcaatgac accggcatta agcgcaaaat accacttgcc aattgatcta aattcgtatt
    16501 ttaataattt tccaaacatg cctacctcct aaaccttgta gatctctcta aataatgaat
    16561 caatcgattg ctgatgctga actcgtaaat catcagcgtt tccagaaagg cagagcttac
    16621 cattttttaa gaaaatagct tcatcaagta caggctcaat gtctgagatg aggtgagtag
    16681 aaatgataac agaggcttgc tcagagtaat tattaataat ggttttaaga atataatctc
    16741 ttgctgccgg gtcaacccct ccgataggct catcaaggat atagagcttt gctttgcggc
    16801 tcatcacgag gataagctgt gccttttcct tatttccctt tgataggttt ttaaagcgct
    16861 cttcagcatc taagtctaaa tccttcaaga gactggtcgc tttatctctg tcaaaatcgg
    16921 catagaaatc accaaaaaag tctagcatat ccttgatttt catactttca ttaagatagg
    16981 tcgtatctgg taagtaagaa atgatttttt tagtttctac agatggtcta aagccgtcaa
    17041 taacaatgtc tcccttgtct ggctgtaaaa gtccgttgat tagcttaatt agcgtagttt
    17101 tgccgctacc atttggtcct agtaagccga taatttttcc agaagggatt gttatggtta
    17161 aatcatcaat agctaattgt tttttgtaag attttgagac gtggtgcagc tgtaatagtt
    17221 gtgccattag tttgatccct cctctaaaaa ggtacttaaa acaggaatga tttctgaacg
    17281 ttcaaaacct attttgatca tattgctaat aaaggacttg agctcgttga tggccagctc
    17341 tcgtcttttg cgcgcgataa gctcttggtt atctgttaca aatcggccgg cagttcgttg
    17401 cgagtaaact atgccttcac gttctaattc ggtaagtgct ctttgcatgg tgttgggatt
    17461 aacgccggca atttcagcat attctcggac agtcggcagc tgatctccac ttttgatctc
    17521 ttggctgaca atttgcagca tgatatgctg tgctatctgt gcgtaaatag gagatttctc
    17581 atcaaatttc caagacatac tgtctccttt ctttctaaaa tctgcgatta atatttgtac
    17641 taattaaatg atacaaaaaa acgattgact tgtcaagcct tgtgtgtcat ctctagttac
    17701 atattggctt gcaatgctag tgggattcct gctgatagtg gtgcagtaaa gacagatcac
    17761 tgctattaaa agcttaaaat ctgggcagta aagtcttttt catagtataa tagtaataag
    17821 aatactaaag gagatgtcca tgtttgctca gttagataca aaaacagttt attcctttat
    17881 ggatagcttg attgatttag accattattt taaacaagca aaacgattag gctatcaagc
    17941 catagggatt atggatcagg ataatctata tggggcatat cattttatta agggctgtca
    18001 aaggcatgga cttcagccaa ttttaggtct tgaggtggct attacagtca aagagcaggc
    18061 tcttacgctg aagcttgttg cgaaaaatga tacaggctat cagcagctct taaagctttc
    18121 aaccgaaaaa atgtctggag agctggatct agatacattg gtgcagtatt tagaagggat
    18181 agcagttatc gttcccttta ggcagagctt gagtgattta gggcttcctt ttgattactt
    18241 cattggtatt gatgaggcaa gtgacttgtc aaagataggc tctacagaaa gactgattcc
    18301 gtttagaacg gtacgttatt ttgatgacac agagactgag actctgcaaa tgctgcatgc
    18361 cattcgtgat aatattagct tagcagatac ggctctagta gccaaggatc agtttttagc
    18421 gccttgtcag gagatgacag ctattttcca ggaaaagtgc cctgaggctt tggtgaatct
    18481 cgtaaaccta acagcttcga ttgcttatca ttttgatacc gatttaaagc ttccgagatt
    18541 taaccgcgac aagccagcaa aagaagagct aagagaattg accgaatccg gtctaagaga
    18601 aaggcaattg tggaaggagc cttatcaatc tcgtctggca gaggagctgg ctattatttc
    18661 agatatgggg tttgatgatt attttctcat tgtctgggat ttgctgcgct ttggaaggag
    18721 tagaggctat tatatgggca tggggcgtgg ttcagcagca ggcagtctag tggcttactc
    18781 gctgcgcatt actgggattg atcctgtcaa aaacaattta ttgtttgaac gctttttgaa
    18841 taaagaacgc tacagcatgc ctgatattga tattgatttg cctgatattt accgctcaga
    18901 gtttcttcat tatgttcgag accggtatgg tagtgagcac tcagctcaga tcgttacctt
    18961 ttcgactttt ggtcctaagc aggctgttcg tgatgtgttc aaacgctttg gtgtcccaga
    19021 atacgagcta acaagcctaa ctaaaaaaat tgggttcaag gataccctga gcactgttta
    19081 tgagaaaaat atagccttca gacagaccat taatagccgc ttagagtttc aaaaggcatt
    19141 tgagatagct aagcgcattg aaggcaatcc aagacagacc tctattcacg ctgctggtat
    19201 cgtgatgagt gatgaccatc tgaccaatca tattccctta aaaaaggggg aggatatgat
    19261 ggtgactcag tatgatgcca gtgctgttga agctaatggc ttgctgaaaa tggattttct
    19321 tggtctgaga aatttgacgc ttgtacagaa aatgcaggaa aaggtggtca acgattacgg
    19381 tctttcaatt gacattgaag ctattaacct agaggatcct gaaacgatag ccttgtttgc
    19441 taggggtgat accaagggca tttttcaatt tgaacagcat ggtgcgatta gcctgttaaa
    19501 acggatcaag ccgactagct ttgaggaaat tgttgcgaca accagcttaa atagaccggg
    19561 agcaagtgat tacacgcaga attttattaa gcgccggcag ggacaggaaa acattgattt
    19621 aatagatccg gtgattgctc cgatattaga gccaacctat ggtatcatgc tttatcagga
    19681 gcaggttatg cagattgctc aagtttatgc aggctttaca cttggaaagg ccgatttgct
    19741 acggcgtgct atgtctaaga aaaacctcgt tgagatgcaa agaatgcagg aggattttct
    19801 gactggtgct agagccttgg gtcgctctga ggagacagcc agactattgt ttgcacgtat
    19861 ggaaaaattt gcaggctacg gctttaaccg cagccatgcc tttgcttatg ctgccctagc
    19921 ctttcagctg gcttatttta aagcgcatta tcctgaggta ttttttgatg tcatgatgaa
    19981 ttattctagc agtgattaca tcactgatgc gttggatttt ggctttgagg ctgcgcaggt
    20041 gacgataaac actattccct ttaatgataa gattgagcgt cataagattt atatgggctt
    20101 aaaaaacatc aaaggccttc ctagagaatt ttcgtactgg attatcgaaa acaggccctt
    20161 taccagtgtt gaaaactttt tgtgcagcat tcctgaaaaa taccagaaaa tcagcttttt
    20221 agagcccctt atcaaaatag gcttgtttga tgggtttgaa aaaaatcgcc aaaaaattat
    20281 taacaatttg gaagggctgc taacctttgt caatgaattg ggatcacttt ttgctgattc
    20341 ttcctttagc tgggtagaga ctgaggatta ttcagctgct gaaaaatatt actttgagca
    20401 ggatttgctt ggtgttggca tgagcaagca ccccttgcta gctgtcgctg aaaaaagcac
    20461 agtagcagtc acaccaatca caaagctagt gaaggataca gaagctactt tgctggttca
    20521 aatagatgcg atcagggtta ttcggacaaa atcaagcgga caacagatgg cctttttgag
    20581 tgtcactgat accaagcaaa aattagatgt tacccttttt cctgagcaat atgctgtcta
    20641 taagcaagac ctaaaagaag gtcacattta ctatatcaat ggcagggtaa aagaaagaga
    20701 taaccgcctg cagctagtct gtcaccagct tcgattagct cagagtcaaa ggtattggct
    20761 attggttgaa agccatcagc atgatgctgc tatttctgac atattaacgg ccttttcagg
    20821 ggaaactcct gttattatcc attatcaaga aggcaaagaa accttagagt taaaccatat
    20881 tagggttgat gttagtaagg atttggagga ggctattagc ccctacgtgt tgaaaacggt
    20941 ttttcgataa aaatagcgaa ttagtgaagt aatttgcaaa cgaatgtgct ataataaaaa
    21001 cgttaaatta attaaaggag taccaaaaaa tgaaacgtat tgctgtttta accagtggtg
    21061 gtgacgcccc tggtatgaat gctgctattc gtgcagttgt tcgtaaagca atttcagaag
    21121 gaatggaagt ctatggtatt aaccgcggct atgctggtat ggttgatggt gatatctttc
    21181 cactaggctc aaaagaggtt ggtgataaga tttctcgcgg cgggaccttc ctttattcag
    21241 ctcgctaccc agagtttgct cagcttgagg ggcaattggc tggtattgag cagctaaaaa
    21301 agcatggcat tgaaggggta gttgtcattg gtggtgatgg ttcttaccat ggtgcgatgc
    21361 gcttgactga gcatggcttc cctgcagtag gtatcccagg gacgattgat aacgatattg
    21421 ctggaacaga ctatactatc ggatttgaca ctgcggtcaa tactgcggta gaggctattg
    21481 ataagcttcg cgatacctca tcaagtcatg gacggacctt tgttgttgaa gtgatgggac
    21541 gcaatgcagg tgatatcgca ctttgggcag gtattgcaag tggagcagat caaatcatcg
    21601 ttcctgaaga ggaatttgac attcataaag tggtctcaac aattaaagac gattttgaaa
    21661 atagaggaaa aaatcaccat attatcgttt tagctgaggg cgttatgagt ggcgaggcct
    21721 ttgcgcagca gctaaaagaa gctggagatg aaagtgacct tcgtgtgaca aaccttggtc
    21781 atatccttcg cggtggctct ccgactgcgc gtgatcgtgt gattgcgtca tggatgggag
    21841 cgcacgctgt tgagctgctc aaggaaggca aaggcggctt ggctgttggt atccataacg
    21901 aagagcttgt tgaaagtccg attcttggaa gtgcagagga cggtgccttg ttcagcctta
    21961 ctgatgaggg taacattgtt gttaataacc cgcacaaggc tcgcttagac tatgctgctt
    22021 tgaaccgttc attagcacaa taggataagt aagatctggt aatctttgtt aatcaactaa
    22081 aaaataaggg agtttcataa taaaatgaat aaacgtgtaa aaattgttgc aacacttggt
    22141 cctgcggttg aaattcgcgg tggtaaaaaa tatggtgagg acggctattg ggctggtcag
    22201 ttggacgttg aacaatcagc taaaaaaatt gctgaattaa tcgaagcagg tgctaacgtt
    22261 ttccgcttta acttttcaca tggtgaccac aaagagcagg gtgaccgtat ggctactgtt
    22321 cgtcttgctg aaaagctggc acgtcaaaag gttggtttcc ttttggatac aaaaggacca
    22381 gaaatgcgta cagaattgtt tgctgatgat gccaaagaat atagctatgt gactggtgag
    22441 cgtattcgtg ttgcgacagc acaaggcatt caatcaactc gtgatgtgat tgccttgaat
    22501 gtagctggtg ctcttgatat ttatgatgag gttgaggttg gccacactat tcttattgat
    22561 gatggaaagc ttggcttaaa ggttatcgag aaggacattg caaagcgtga gttcatcgtt
    22621 gaggttgaaa atgatggaat cattgcaaag caaaagggtg ttaatatccc taataccaag
    22681 attcctttcc cagccttagc agaacgtgac aatgctgata ttcgttttgg tcttgagcaa
    22741 ggtcttaact ttattgctat ttcatttgtt cgtactgcca aggacgttga agaggttcgt
    22801 gagatttgtc gtgaaacagg caatgagcat gttcaattat ttgctaaaat cgaaaaccaa
    22861 caaggtattg ataaccttga tgaaatcatc gaagctgcag atggtatcat gattgctcgt
    22921 ggtgatatgg ggattgaggt gccatttgaa atggttccag tcttccaaaa aatgattatc
    22981 accaaggtaa atgcagcagg taaagcagtc atcaccgcaa ctaacatgct tgaaacaatg
    23041 actgaaaaac cacgtgcaac tcgttcagag gtatctgacg tttttaacgc ggttattgac
    23101 ggtacagatg cgacaatgct ttctggtgaa tcagcaaatg gtaaataccc tgttgaagca
    23161 gttcgtacaa tggctacaat tgataaaaat gcacaaactc ttcttaatga gtatggtcgt
    23221 ttagattcat ctgctttccc acgtaccaat aaaactgacg tgattgcttc agctgttaaa
    23281 gatgcaacac actcaatgga tatcaagctt gttgtgacca ttactgaaac aggaaacaca
    23341 gctcgtgcca tttctaagtt ccgtcctgat gctgacatct tggctgtgac ctttgatgaa
    23401 aaggttcaac gcgccttgat gattaattgg ggtgtgattc cagtgcttgc tgaaagacca
    23461 gcatcaacag atgatatgtt tgaggtagca gagcgtgtag ctcttgagac tggtttggtg
    23521 caatcaggag ataatatcgt tattgttgca ggtgtgccag ttggtacagg tggtacaaat
    23581 acaatgcgtg ttcgcactgt aaaataatag ctttccataa gctttagcta ttttgctcta
    23641 tcagataatt taaggcaaac aatgatactt aaaaattgtt tgcttttttt attagtcata
    23701 tcatgttata atgagactat agactaggag ttattatggt aaagcgagat tttataagaa
    23761 atatattgtt gttattgatt cttattgtgg gagctgtcct tcttagaata tttgtttttt
    23821 cgacctatcg agtcacgtca gaggcttcaa atgcctattt gaataagggc gatttaatca
    23881 ccattaagaa aaatattgag cctaaatata aggattttgt ggtttatacg gttgacaaaa
    23941 aggattatgt gagccgggtt gtagcagtag caggtgatcg tgttacctat atggacgata
    24001 ttttttacct gaacaatatg gttgaatccc aatcctatct tgagagtatg aaggcaaagt
    24061 atctcaatcg tgcccctatt ggtacgcttt atacggagga ttttacgatt tcgacggtta
    24121 cttctggaaa atacgatagc attcctaagg gaaaatacct tttgctaaac gataacagaa
    24181 aaaaccatca tgatagccgt cagtttggct taattgacgt gtcacaaatt aagggattag
    24241 taacatttag agtgcttcct ttgaaagact ttggatttgt agaggtagag tagctttaag
    24301 gctgctctat tttgtttctc aaaatatgac tataccaatt ttcttgttga caagattttt
    24361 ctgaagttat atactctaaa tataacgttt tagtcggttt atatctgact ataccaatta
    24421 tattgatcat taaagaaagt agtaagctag cttactgagg tgttaagtta tgtgtggaat
    24481 tgttggagtt gtcggtagtc gtaatgcgac tgacatcttg atgcagggac tggaaaaatt
    24541 agagtatcgt ggttatgatt cagctggtat ttttgtgtca gatggcagga cgtccaattt
    24601 ggtaaaatct gttggacgca ttgcagattt acgctctaag attggcattg atgttgttgg
    24661 aacgaccggt attggtcata cacgttgggc aacgcatggt caagcaacag aggaaaatgc
    24721 tcaccctcat acctctcaga caggtcgctt tgttcttgtt cataatggtg tgattgaaaa
    24781 ttacctccag atgaaggagc agcaccttgc tggacacacg tttaaaggac aaacagacac
    24841 cgaaattgca gttcatttga ttggagcatt tgttgaagaa ggctgttcag tcttagaggc
    24901 ttttaaaaag gctttatcaa tcattgaagg ctcctatgcc tttgccttaa ttgatacaga
    24961 ggatatggat acgatctatg tcgctaagaa taaatcccca ttgctgattg gccttggtga
    25021 gggctataac atggtttgtt cagacgctat ggccatgatt cgtgaaacca gcgaatttat
    25081 ggaaatccat gacaaggagc tggttatcct gacaaaggat tcagcaaggg tgaccgatta
    25141 tgctggaaat cctattgagc gtcagtcata cacagcagag cttgatcttt cagatattgg
    25201 caagggaacc tatccatttt acatgctaaa ggaaattgac gagcagccaa cagtgatgcg
    25261 tcgcttgatt tcaacctatg cagacgccaa gggacagatg atgattgatc cagctatcat
    25321 aaggtctgtc caagaggctg atcgtatcta tattcttgca gctgggacct cttatcatgc
    25381 tggctttgct tctaagtcaa tgctggagcg tttgactgat acgcctgttg aattaggggt
    25441 tgcttctgag tggggctaca atatgccgct attgagcaaa aagccaatgt ttatcctctt
    25501 gagccagtcc ggtgagacag cagatagccg tcaggttttg gtcaaggcaa atgagctggg
    25561 aattccaagc ctaacagtga caaatgttcc tggctcaacc ctatcacgtg aagcgaccta
    25621 cactatgctg cttcatgcag gtccagaaat tgcagttgca tcaactaaag cctacacagc
    25681 tcaggtcgct gcacttgcct ttctagctaa ggcagttggt gaggctaatg gcaagaagga
    25741 agctattagc tttgatttgg ttcatgaatt gtcattggtc gctcagtcta ttgaggccac
    25801 cttatctgat aaggagctga ttgctgagaa ggttcaagag ctcctagcaa caacacgcaa
    25861 tgctttttat atcggccgag gcaatgatta ttatattgct atggaggctg cactaaaatt
    25921 aaaagaaatt tcatacattc agtgtgaagg gtttgcagct ggtgagctaa agcatgggac
    25981 tatttcattg attgaggatg gcacacctgt tattggactt atttcttcaa gtgagctggt
    26041 tgctgcacat acacgtggca atatccaaga ggtggctgcg cgtggcgctc atgtgttgac
    26101 agttgttgag gaggacttag agcgtgaggg agatgacatt attattaata aggtacaccc
    26161 attcttagcg ccgattgcta tggttattcc gactcaatta attgcttact atgcgtcctt
    26221 gcagcgtggt ttagatgtag ataagcctcg taatttagcc aaggctgtta cagttgagta
    26281 atagttgcct gcttaaaatg aggcagcagg gtcctgaagc ctatttgaaa cgagcttgac
    26341 atgatgctgt gtcagactcg ttttttagtg cttgcttggt cttatgataa cgtattcatc
    26401 ttgtcaaata agcatttctg aagtaaaata ttaacgttaa gactaagaag cttaggagag
    26461 taagatgaca ttaccaaatt gtttacaatg cgattcagag tatgtttatg aggacgggca
    26521 tttgctaatc tgtccgatgt gttcctttga gtggacacct ggtgaggagg agcctgagga
    26581 agatgggctt gtcgttttag atagtaatgg gactagatta gctgatgggg acactgttac
    26641 gatcattaag gacctgaagg tcaagggagc gccgaaggat ctcaagcagg gaactcgtgt
    26701 taagcatatt cgtcttgttg aaggtgatca caatattgat tgtaagattg atggctttgg
    26761 tgcaatgaag ctaaaatcag aattcgtcaa gaagatttaa taacaataag caaccagatg
    26821 actggttgta tttttataga aaagtacttt tcaatccatc agaaaatttg gtataatgga
    26881 taaactattt atatctagga gacaacatga cgtatattat gcaggtttta cccagcttgc
    26941 tggatggtgc cttaatcact ttacaggttt tctttattgt aattgtatta tccattccct
    27001 taggagctct tttagctttt ttgatgaggg ttgactttaa gcccttgcag tggctattga
    27061 cgctctatat ttgggttatg aggggaacac ccttattgtt acagctcatc tttttttatt
    27121 atgttttgcc aagtgtgggt gttacctttg atcgtatgcc ggcagcgatt ttggctttta
    27181 ccttaaacta tgctgcttat tttgccgaga tttttcgtgg cgggatagag actattccaa
    27241 atgggcaata tgaggctgca aaggtgctga agcttagtcc ggtacaaact gttcgctatg
    27301 ttatcttgcc tcaggtgttc aagattgttt taccaagtgt tttcaatgag gtgattaact
    27361 tagttaagga ttcttccttg gtatatgtgc taggagtagg ggatttgcta ttagcaagca
    27421 agactgcggc aaatagagat gcaaccttag caccgatgtt tattgcaggt ttgatttatt
    27481 tgctcttaat tggtttggtc accattttat cgaagcaggt tgaaaaaaga tttaattatt
    27541 atcagtaagg gggtcatatg ttagaactga acaatatttc aaagcgattt ggtcacaagc
    27601 agatctttga tggctttcat ttgaccgttg aagatggtga ggttttatct ttggtagggc
    27661 catctggtgg tggcaagact actttgctcc gaatgctggc tggcttagag tctattgatt
    27721 cgggaaatat tagctataat ggcgagtctg ttcctattga tcatttagaa aaaagaagcc
    27781 tgcttggttt tgtttttcag gatttccaat tgtttccaca tttgacggtg ctggataatc
    27841 tcatcttgtc tcctaccatt accatggcta tgccaaggcc tgatgcaaag caaaaggcta
    27901 tggagctgct ggagcgccta ggtctcaaag agcatgcagc tgcttatcct tattcgctat
    27961 ctggtgggca aaagcaaaga gttgccttgg ctagagcgat gatgattgac ccacagattg
    28021 taggctatga tgagccgaca agtgccttag accctgaatt acgtcaggag gttgagaaat
    28081 tgattttgca aaatcgtgag atgggcatta cccagattgt tgtcacccat gatttgcagt
    28141 ttgctcagac catttctgat cgtatcatca agatcaatcc taaatagaag aagaggtagt
    28201 gctatgacgt taaaaaagac ccttctagca gccctatttg ctgctacagc tacgctttta
    28261 gtagcttgtg gcgctagtaa taaacagact agctcagatg gctggaaatc ctacaaggag
    28321 aaaaagacga ttacgcttgg ctttgataac acctttgtgc caatgggcta taaggacgag
    28381 tcaggaaaaa acaccggctt tgatattgag ctagcaaagg ctgtttttga ccaatatggt
    28441 atcaaggtta agtatcaagc cattaactgg gatctcaagg aaactgagtt aaacaatggt
    28501 aaaattgatc tgatttggaa tggctattct gtgacaaaag agcgccaagc taaggtggcc
    28561 tttacagagc cttatatgaa aaatgagcag gtcttagtga ctcaaaaatc atcacagata
    28621 agctcatttg ctgatatgaa aaataaaacc ttgggtgctc agtcaggctc atctggttat
    28681 gatgccttta caagtcatcc taaggtgcta aaggaccttg tcaagggaaa tgatgctacc
    28741 caatatgaaa cctttacaca agcctttatc gatttaaaaa acaagcgtat tgatggcctt
    28801 ttgattgata gggtttatgc caattattac cttcagcaag aaggtgagct agaccgctat
    28861 aacattattg cgagtgagtt tgaaggtgag gattttgcag ttggtgtccg aaaagcggat
    28921 aaaaccctac aaaaaaagat tacacaagcc ttaaaatcgc tctatcagga cggtaccttc
    28981 caaaaaatct ctaaaaaatg gtttggcgaa gatgtcgcag cagatcagtt gaggtcatag
    29041 tcataggacg caagcaagac ctaatgagct tagaaggcag aatggctgga tagaaaaaaa
    29101 cttatcctat cagggtaagt tttttgtgtg cttgtgactg atgatatagc tgcttgttag
    29161 ctgatacgct tgatatgata gtgtttttta attgttatgg agtttgttat tggtgtgatt
    29221 tgatgatata tcaggtgcca agcttcgtgt cgtctccaga tactggtgtg ctgattgccc
    29281 tgcagctgat aggtgactag cttggtgttg tggctgatgg attgcataca aaaggcttca
    29341 agctgattgg aagaagaacg ctgctgctct aaaaattgct tggcattgta agcctgtcca
    29401 ttgcgatcaa tgaaggtaaa ggtctcggca atgagctctt gataatctgg gatttgactt
    29461 agcatgattt tctcgttttt gtagagcttt ttgtaaacat gttcacagtt gtcatcttca
    29521 ggaagttttg caggctcaac atgaatatca atatcataaa cagcaaattg ctcactcaag
    29581 agctgttcga cctgctcggt tatggcgtga ctttcataga cagaaaggtc agggtgcatc
    29641 tcaaggacaa tatctaaata gacattgctt ccgtaagtgc ggccgcgctg tgatttgaca
    29701 gcaatgattt tgggaatttt caatatggcc ttttcatatg ctttgagctg cttgctgtca
    29761 aagccatctg ataagctaaa ggcgcttgcc ataaaaatat caaaggctgt ttttagaatg
    29821 aaaaaggtaa tgataagggc agccagccta tcaataatag gtagctttaa ggaagcagcg
    29881 ataatagcaa tagaggttcc aatagaggtc acagcatcag aaagattatc cttagaggct
    29941 gcaaccaagg cactggatct tacctttttt gataacgctt tattaaaagc atatactcca
    30001 agcatcacaa gggctgaagc gatcccaaca atagcaccta atggatcgat agcagactgc
    30061 ttaccactaa tcatctgttg aatggtttgc aggagaacct gaaagccaac aataaacatg
    30121 ataaaggagg ttattaagct tgaaaggtct tcgattttcc agtggccaaa gcggtgattg
    30181 gcgtctgctg gctggctggc cagatgaagt ccgatgagca gagcgacatt accaacgata
    30241 tcagacaggt tgttgaagcc atcggcaatc aaggagctgg catttaaaag atagccagca
    30301 agaagctttg tgatgctaag ggccaaatag gcaacaatgc taacaatggg ccctcttttt
    30361 gctaaccgaa ggttttctac tggattgttt ggcataaaaa ctcctttgta actgatgctt
    30421 tcattatatc ataaaagcta agacaagcta aaagcctaga gctatcctaa atagggtatt
    30481 ccaggctttt tgacagctta tttggtgctt tggcgcttaa aatatgccct tgtctcaaaa
    30541 atgacaacag gagataaggc tagtagggcg ataagatttg gcagagccat caggccattg
    30601 acaatatctg ccagtatcca aatcaactcc agcttaagaa agccaccaag tcctaccatg
    30661 acaacaaaga tcaagcgaaa atagctgagg tgtgtcgtgc caaataaaaa gataaagcag
    30721 cgctcaccat aataactcca gccgagaata gtcgtaaaag caaaaagaac aagcgacagg
    30781 gtcaaggcat aggtgcccat atgcccaaag atagaagcaa aggcagactg tgttaagggg
    30841 gctccctcta gtgtgctagt ccactgacca gttaccaaaa tagccagacc agtcagagtg
    30901 cagatgatga tcgtgtcaat aaaggttccg gtcatagaaa tcaagccctg ctctactggc
    30961 tccttggttt tagcggcagc agcagcgatc ggagcagagc ctagtcctga ttcgttagaa
    31021 aaaaccccac gcgcaatgcc cttttgaatg gcgtccttaa ccaagcttcc ggcaaagccc
    31081 cctatagctg ctgtaggggt aatagcggac ttaaagataa ggacaagcat aggaagaagc
    31141 ttagtatagt gaacagcaat aaccgttaag cttgctccaa tataaaagat agccatgaag
    31201 ggaacgactg tttcagccac cttggcaata gcttgaatgc ctccaaaaat aatcatggcc
    31261 acaacagcag ctagcaagac actgattaat ggcgaagaga ctccaagact atggtgtagg
    31321 gatgaggtaa tcgcattgac ctgagcaaat gtcccgattc caaacaaagc cactaaaata
    31381 ccagagacag caaataagct ggctagaggc ctccattttt gccccatacc atttaaaatg
    31441 tagtacatgg gtccacctga aatctgacca ttagcgtcct tagtacggta tttaatggct
    31501 aaaacgccct cggaatattt ggttgccata ccaaagaagg cagcaaccca catccaaaaa
    31561 agtgctccag gtccaccaga ctttatagct gttgcgacac caacgatatt accagtacca
    31621 actgtagcag ctagggctgt tgctagagca gcaaacgatg aaatatctcc ttgcccctca
    31681 ttcttagcaa aaataagcct aaaggcctta ggcagcttga tgacttggag aaggccaagt
    31741 ctgctggtga ggtaaacgcc agtaccaagc agcagtagca gcaagggtgc tccccaaact
    31801 aaatcatcaa tccattttgc agcagctatc atgtttaact cctcaactct cctaaccaat
    31861 gctgccaaaa gaaaaagcca cccctacgga tagcctctga agcatatgac aaaacagcaa
    31921 gcacaaaaaa tgctaagaga gcatgatcat gcggcttgat attttatctt ctgtcctttt
    31981 gcctgagaga ttgagcagtc ttgccttgcc ccttcggcgc ctaataggtc tctccagaag
    32041 cccgtccatc aagcagtccc gtccaacacc tgaacacctg agagtataac tccttcggcg
    32101 aaatccattc ttctcctgca tgacatcatt cggtttatta aattatgtct atgataccca
    32161 aaaagcccag tgatgtcaac aagcaattta attgatggct aattccttgt ttttatggta
    32221 acatcattgt cctctttttt ctttttgact gaaacatgat ataatcttaa ggttaataaa
    32281 agtcacttat tggacgatat gaggagaaag catgaatcct ttattagatg gaatgaatga
    32341 taaacaggca gaggcagttc aaacgactga gggccccttg ttaattatgg ctggtgccgg
    32401 ctctgggaaa acgagggtat taacccaccg cattgcctac ttgattgatg aaaaatttgt
    32461 taatccctgg aatattttgg cgattacctt taccaacaag gctgcgcgtg agatgcgaga
    32521 aagggccttg gccttaagcc cagctaccaa ggataccttg attgcgacct ttcactcaat
    32581 gtgtgtccgt attttacgtc gtgaggcaga tcatattggc tacaatcgga atttcacgat
    32641 tgttgatcca ggagaacagc ggaccttaat gaagagaata gtaaaggctc taaatttgga
    32701 tcctaagaaa tggagcgagc gttcgatttt agccactatt tcaaatgcta aaaatgatct
    32761 cttagatgaa agagcctatg agctaggagc ctctgatttg tatagccaga cagttgcccg
    32821 ctgctacaag gcctatcagg aggagctcag acgaagtgag gcgatggatt ttgatgattt
    32881 gattatgatg accttacgcc tatttgatca aaatcctgac gttctagcct attatcagca
    32941 gcgttatcaa tatattcatg ttgatgaata ccaagacact aaccacgctc aatatcagct
    33001 agtgactctt ttagcctcac gttttaaaaa tatttgtgtt gtcggtgatg cagaccagtc
    33061 catttatggc tggcgtggtg ctgatatgca aaatatttta gattttgaaa aggattaccc
    33121 tgatgcaagg gtggttttgc tggaagaaaa ttatcgctcc accaagaaaa tccttcaggc
    33181 ggctaacgaa gtgattcagc ataatcgtca tcgccgtccg aaaaaactgt ggactcaaaa
    33241 cgcagacggt gagcagattg tttattatag ggcaaatgat gagcgtgacg aggctgtttt
    33301 tgtcgcctca accatcagca atatgtgtct agagttagga aagagcttta aagactttgc
    33361 tgttttgtat cgtaccaatg ctcagtcccg tacaattgaa gaagccctgt taaaatcaaa
    33421 tatcccttac acgatggtcg gaggaaccaa attctacagc agaaaggaaa ttcgtgatgt
    33481 gattgcctat ttgactgtgg ttgctaatcc gtcagataat ctctcctttg aacgaattgt
    33541 gaatgagcct aaacgagggg taggaccggg aaccttggat aagctccgcc aatttgctta
    33601 tgggcaagag cagtcattgt tagaggccgc ttcaagcctt gagcaatcac cgctaaaagg
    33661 aaaggctgcc caagccatgc tggccttagc gagtctctta agtgatttga gagctgattt
    33721 agaccagctg agcattacag ccctggccga ggccttgctg gagaaaaccg gctatctgga
    33781 tatgctgcgc gtccaaaata ccttagaaag tcaagctagg attgaaaata ttgaagaatt
    33841 cctgtctgtt accaaaagct ttgatgacct atcagcacag cagcaggagc atgaagcagg
    33901 tattgatcgc ttaggaagat ttctcaatga ccttgctttg attgctgata gtgatgatgg
    33961 caatgcagaa accgctgagg taactttgat gactctgcat gcagctaagg ggctagaatt
    34021 tcctgttgtt tttctcatag gtatggagga gggagtcttt cctttagccc gagcagccga
    34081 ggatcaagat gagctagaag aagaaaggcg actagcctat gttggcatta ccagagccga
    34141 ggaatgcttg tttttaacga atgccaatac acgtacccta tttggtaaaa gcagctataa
    34201 tcgcccaaca aggtttttaa aagagatgtc agagaacctt ttaagcttcc aaggcttggc
    34261 aagacctgct catgcttcct ttggtgtgac attttcgcag cagggtcaac gacaatttgg
    34321 cacaggaatg agtctatcag aggctatcca gtccagaaaa tcaatggcac agcctgccag
    34381 agcagcctca acatctacac cgctgccctt tggaccgaat gcagctactt caaagcaagc
    34441 cgttgattgg cagattggtg atattgccca tcataaaaaa tggggtgctg gaacggtttt
    34501 agaggtcaag ggatctggta agaccatgga attaaccatt agctttcctg atgtcggatt
    34561 aaaaaaactc cttgccagcg ttgctcctat tgaaaaaaaa taaaaggtac agcttatggg
    34621 caatttgcat agtcacttgg ataagggctt tgcaattgcg gtttagttct gcgatttagg
    34681 aaaagaagta agcaaggatt ttatcagtta accacatacc aagcttttga tggccttgat
    34741 gccggagaga gcttggtatt tttttatttt taaaaaaatc acaaaaaatg atttattctg
    34801 agcata
//
LOCUS       DARYSY010000020        34183 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYSY010000020 DARYSY010000000
VERSION     DARYSY010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34183
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..1032)
                     /gene="xerS"
                     /locus_tag="TVR04_000865"
     CDS             complement(<1..1032)
                     /gene="xerS"
                     /locus_tag="TVR04_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1269568.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYILDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNTYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEHKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHI"
     gene            complement(1189..1626)
                     /locus_tag="TVR04_000866"
     CDS             complement(1189..1626)
                     /locus_tag="TVR04_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1269569.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYLILRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            complement(1734..2672)
                     /locus_tag="TVR04_000867"
     CDS             complement(1734..2672)
                     /locus_tag="TVR04_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEL1269570.1"
                     /translation="MQHYYTPKSKHLTLTERRMIERWLQEELSNREIARRLAKAPQTI
                     HNEVKRGQVRQQVRKGKFEVIYSADFAQKAYQNNRKRSVKQVSLTKELKEKMTHDIKQ
                     KYSPEMMVKAKGIPVPISTIYYWIHHGHLGLTKADMLYPRKEKAKKKHASPNFKPAGK
                     SIEERPESINKRENIGDFEMDTVIQTRAKNECLLTLTDRKSRYQIIRLIPDKSASSVN
                     KALKTILRDYQINSITADNGAEFSRLAEVFDPDHIYYAHPYSSWERGTNENHNRLPKG
                     SKNATQQQVAFIENWINNYPKKLFNYKSPKEFLQTG"
     gene            2897..3589
                     /locus_tag="TVR04_000868"
     CDS             2897..3589
                     /locus_tag="TVR04_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1269571.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQQEKIFALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQNSFDYDGAIYAVEWEGQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(3920..4714)
                     /locus_tag="TVR04_000869"
     CDS             complement(3920..4714)
                     /locus_tag="TVR04_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269572.1"
                     /translation="MIEEIPQLYSKDTIIYVYEEKIIMMKNIVSQVIDKAVGQITDIF
                     KMKLKTFIEERNKNAFWNNVVQEAIKATEGIDEEIGRYIFSRLSIVGLERQLFDENYD
                     NIHRNFVLTLAVELCKFDKEKDFSISLGIAVVDKWLEKNKLPTDCDGYNVEELKRIIS
                     DREELYRNYFKLFEEKNGTDTIRIFYPKNGESWIRWEDNCSVDINVNLSKGLSYGFCR
                     EGFDYYKKICNNDYETLKCAYIENEKEILRFNGFSCNEDNTIIWIR"
     gene            complement(4927..6489)
                     /gene="guaA"
                     /locus_tag="TVR04_000870"
     CDS             complement(4927..6489)
                     /gene="guaA"
                     /locus_tag="TVR04_000870"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1269573.1"
                     /translation="MTEISMLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            6776..7474
                     /locus_tag="TVR04_000871"
     CDS             6776..7474
                     /locus_tag="TVR04_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1269574.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            7686..8018
                     /locus_tag="TVR04_000872"
     CDS             7686..8018
                     /locus_tag="TVR04_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1269575.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8033..9604
                     /gene="ffh"
                     /locus_tag="TVR04_000873"
     CDS             8033..9604
                     /gene="ffh"
                     /locus_tag="TVR04_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1269576.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRKRAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(9757..10980)
                     /locus_tag="TVR04_000874"
     CDS             complement(9757..10980)
                     /locus_tag="TVR04_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1269577.1"
                     /translation="MTNVAFYSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNPKALAIIKHLKQFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTIYSDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKGFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(11205..12176)
                     /locus_tag="TVR04_000875"
     CDS             complement(11205..12176)
                     /locus_tag="TVR04_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1269578.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEESKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDGLMGN"
     gene            complement(12489..12929)
                     /locus_tag="TVR04_000876"
     CDS             complement(12489..12929)
                     /locus_tag="TVR04_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1269579.1"
                     /translation="MTKKVYLSLLTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(12926..13861)
                     /locus_tag="TVR04_000877"
     CDS             complement(12926..13861)
                     /locus_tag="TVR04_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1269580.1"
                     /translation="MIRGFKKTIVAVGLLVVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAKNTSIHSYEPSPTVVARIYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHLTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     GLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKINLETLYRVLESET"
     gene            complement(14316..14729)
                     /locus_tag="TVR04_000878"
     CDS             complement(14316..14729)
                     /locus_tag="TVR04_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1269581.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPERHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDREACGLRHLAFHVKPIEAYIDQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(14827..15582)
                     /locus_tag="TVR04_000879"
     CDS             complement(14827..15582)
                     /locus_tag="TVR04_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1269582.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDNVLKAFNHSYNQMST"
     gene            complement(15587..18082)
                     /gene="gyrA"
                     /locus_tag="TVR04_000880"
     CDS             complement(15587..18082)
                     /gene="gyrA"
                     /locus_tag="TVR04_000880"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1269583.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERIEAIIKEEMEEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGNEDIVVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAITQTDTALAEAPINSSKE"
     gene            18274..19257
                     /locus_tag="TVR04_000881"
     CDS             18274..19257
                     /locus_tag="TVR04_000881"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1269584.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFSKEEFASAAKN"
     gene            complement(19478..20845)
                     /locus_tag="TVR04_000882"
     CDS             complement(19478..20845)
                     /locus_tag="TVR04_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1269585.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21095..21697)
                     /locus_tag="TVR04_000883"
     CDS             complement(21095..21697)
                     /locus_tag="TVR04_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1269586.1"
                     /translation="MFRVLKRILGLAFLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEVDVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHSIELATTYSRIVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(21698..22675)
                     /locus_tag="TVR04_000884"
     CDS             complement(21698..22675)
                     /locus_tag="TVR04_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1269587.1"
                     /translation="MLDIYIKGIVIHQFTPNDIELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTISTDLLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     AGEPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(22678..23937)
                     /locus_tag="TVR04_000885"
     CDS             complement(22678..23937)
                     /locus_tag="TVR04_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1269588.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETERLDYAAIL
                     KQAEAVQPKLIVAGASAYSRQIDFEQFRFIADQVGASLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAIARKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HHQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(23949..24380)
                     /locus_tag="TVR04_000886"
     CDS             complement(23949..24380)
                     /locus_tag="TVR04_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269589.1"
                     /translation="MLRPLDQTDCQAICDINDQALGYKVSLELTTSQLEKLRFDKHHY
                     LLGYADAKTNLLLGYLHAECYESLYSEKGFNILALAVKPDHQGRGIGRRLLAALEKKA
                     RQEKASFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(24394..24987)
                     /locus_tag="TVR04_000887"
     CDS             complement(24394..24987)
                     /locus_tag="TVR04_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1269590.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAKTPYWINSGLK
                     TVGFRLPSHPLTAEIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKIDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(24959..25807)
                     /gene="prmC"
                     /locus_tag="TVR04_000888"
     CDS             complement(24959..25807)
                     /gene="prmC"
                     /locus_tag="TVR04_000888"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1269591.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEESDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFAIYRR
                     IIEHASAYLTTSGKLYFEMGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(25804..26886)
                     /gene="prfA"
                     /locus_tag="TVR04_000889"
     CDS             complement(25804..26886)
                     /gene="prfA"
                     /locus_tag="TVR04_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1269592.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEGKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(26929..27498)
                     /locus_tag="TVR04_000890"
     CDS             complement(26929..27498)
                     /locus_tag="TVR04_000890"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1269593.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            27683..27868
                     /locus_tag="TVR04_000891"
     CDS             27683..27868
                     /locus_tag="TVR04_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1269594.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            27923..28864
                     /locus_tag="TVR04_000892"
     CDS             27923..28864
                     /locus_tag="TVR04_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1269595.1"
                     /translation="MIATDQIKMMGTIIDIYIDSSKAKQQAATIRELLTLYNHRFSAN
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHIILDQGLGSIFLKEKGMSIDLGALAKGYIADKLMAFL
                     IKDGITAALINLGGNVLVHGTNKQRHNGLFYVGIQQPNQKRGQHVGVIKVNNKSVVTS
                     GIGERQLQIGDKAYHHLLDPHNGYPIKTNMASLTIVSQSSLDGELWSSRLFGLEHSFV
                     LSQLNKLPEVEGIIITKDGQVTISDGLQGVFRLHYKH"
     gene            complement(29125..29706)
                     /locus_tag="TVR04_000893"
     CDS             complement(29125..29706)
                     /locus_tag="TVR04_000893"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1269596.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIQQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGTVSFLEADA"
     gene            complement(29897..30880)
                     /gene="guaC"
                     /locus_tag="TVR04_000894"
     CDS             complement(29897..30880)
                     /gene="guaC"
                     /locus_tag="TVR04_000894"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1269597.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            complement(31242..32774)
                     /locus_tag="TVR04_000895"
     CDS             complement(31242..32774)
                     /locus_tag="TVR04_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEL1269598.1"
                     /translation="MPSLLMTFWDRFGDWTRALGEHLQISLLSLLVALLIGIPLAALL
                     SKSKRWSNIILQLTGVFQTIPSLALLGLFIPLMGIGTAPAVTALVIYAIFPILQNTIT
                     GLNAIDPSLVEAGTAFGMTKWERLKIFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGTFILLGIDRNNAQLIVIGAVSSALLAIVFNSLLRYLEKASLRRIAISFAATLL
                     LLLISYTPMFVKRFVNQSNTLVIAGKLGVEPDILINIYKELIEDQSKLKVELKPNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLKKKPKLSNDPNQVYLAAKEGIAEQDQLTFL
                     KPFAYQNTYAVAMPEKIADEFNIKSISDVKKYEKQLKAGFTLEFKDREDGYKGIQDKY
                     GLHLSVATMEPALRYQAIQSGNIQLTDAYSTDAEIVKYQLRVLKDDKQLFPPYQGAPL
                     MKASLLRKHPHLKTILNQLSGKITEEEMQAMNYEVSVKGRAASLVAHDYLVKAGLIAR
                     TK"
     gene            complement(32767..33440)
                     /locus_tag="TVR04_000896"
                     /pseudo
     CDS             complement(32767..33440)
                     /locus_tag="TVR04_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(33451..>34183)
                     /locus_tag="TVR04_000897"
     CDS             complement(33451..>34183)
                     /locus_tag="TVR04_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HEL1269599.1"
                     /translation="TDMVRNVENGVALIEKWLRNKNTIEFLGIWEEMYNANFNSTEFE
                     GIKNEAGFNRFILSVKQWVNKTNSIGIVAKAGRYGGTYAHKDIAFEFASWVSPYFKLY
                     LIKEFERLKEEEQKQLGWDIKRNLAKINYKIHTDAIKNKLVPEKLSKERINYIYASEA
                     DILNVALFGMTAKEWRENYPELKGNMRDYADISQLVCLSNLENLNAVFINEGMDATKR
                     IEKLNAIAIEQMRILTESERIKKLK"
BASE COUNT         9990 a         7251 c         6366 g        10576 t
ORIGIN      
        1 aatatgagta tagaggtctg taacttgggt cgaggcatga ccaagctgat gacttactag
       61 gacctgtgat tttgtagtat cataaagtct cgttgcaagc gtatggcgta gcttatgagg
      121 agttacacga attttaaagc cttcagaata tttacctacc attttttcaa tgcttgaggc
      181 atctatccga ttggggagcc cacgataggc tgttaaaaag aaggctacat cctgtttttc
      241 tgcttgatag cggtcttttc gaactgataa ataggcttct aaatgaggct tggcaaaagc
      301 agcaacattg accgaatctc tcttacctcc cttacgggta acctcaacca gcatcatgtt
      361 gaggttgaca tccttaaggt ctaggttaac tgcctcggat aaccgaatac cagatgccag
      421 cagtagggcg ataatggcta ggtcgcgttc tttatttttt cggaaagaag cctttgcccg
      481 atttgacagc ttatgttcat attctttatc cacatagtct aaaaatgcca tcgtctcatc
      541 gcctaaaaaa agcttttgtt taatattttc agccctggct gctaaggttt ctcttttctt
      601 tttggttgcc acctttttca tgacatttcg ataaaaataa ggctctccat gctcattttc
      661 aacctcctca gtaaggtatt tatacaagct ggatagtgca gaaagggtac gattaatggt
      721 ggtttgcgat accccctttt tagttgaata ggtgttcaag gaaggacgct cacgaagata
      781 gagaataaag gcttccatat cctttttact caaatgctcc agagtagtca agtccacatc
      841 agcaatccta gcagcttttg atagatcaga atcaattaac cactcaaaaa agcgtttgta
      901 ttctttcagg tattcgtaca aggtcgtaaa gctataagga acagaaagct tagattgata
      961 ataatcaagg atataccaag gcatgatgtt tttgtattct tcaattttag taagtagtaa
     1021 gtcacgtttc ataataaatt ctcacaatgt ttcgtcaaca aatgaattat ccattggata
     1081 tcagactgat agtagtatat cacatctcgg gatatttttc aagaaaatta tagtttttcg
     1141 gaaagatata aaattattta atagttattt tgctaagcta aggctgtttt atctgctacg
     1201 atgctgctta aaaatatagt atttactaac aataaaattc aagctaatca ttatggcttg
     1261 gctcaaaatg ctttcaacag aattaatgct ttcagaatca tgttcaacaa ggcttccaat
     1321 gacctctggg tatttttcga ctaataaata ggctaatagc atatctaagc ctaatgttac
     1381 tactctagct aggaaaaaca tggcaaatct aaacaagcgt ttttcggaag tttgcttaaa
     1441 aacatagcta tcgttcatca agaaggcagc tatgatcgct ataatattgg caaagcctgc
     1501 tgatatggtg gcctgatgta accatgaata gatgacatat cgcaaaataa gataaagaat
     1561 ggttgttaga agaccagata tcaggtaatg actgatttca agtgataatt tttgtttgct
     1621 aagcattttt ctttcctatg tgtatttatc ttgactgtta tattttaatg gatctatata
     1681 agtataacat gtttggcatt aaacctaaga cagcgccaaa tttcaagttc aagttagcca
     1741 gtctgtaaaa actctttagg agatttataa ttgaatagtt tctttggata gttgttaatc
     1801 cagttttcaa taaatgcgac ttgttgttga gtcgcatttt tacttccctt aggtaacctg
     1861 ttatgattct cgttagttcc acgctcccaa gaagaatacg ggtgggcata gtagatatga
     1921 tcagggtcaa aaacttctgc taaacgactg aattcagctc cgttatcagc tgtgatggaa
     1981 ttaatctgat aatctctgag gatagttttc agagctttgt tcactgaaga cgcagactta
     2041 tctggaatga gtcggatgat ttgataacga ctctttctat cggttagagt caacagacac
     2101 tcgttttttg cccgagtttg aataaccgta tccatttcaa aatcaccgat attctcacgc
     2161 ttattaatgc tttcaggtcg ttcctcaata gactttccag ctggcttaaa attgggactg
     2221 gcatgctttt tcttagcttt ctcttttcga ggataaagca tgtcagcctt ggtcaatcct
     2281 aagtggccat gatgaatcca gtagtaaatg gtggagatgg gaacaggtat cccttttgcc
     2341 ttaaccatca tctcaggaga gtatttttgt ttgatgtcgt gagtcatctt ttctttgagt
     2401 tccttcgtta gggagacctg cttaacagaa cgtttacgat tgttttgata ggctttttga
     2461 gcgaagtcag ctgagtaaat cacttcaaat tttcctttac gcacttgttg tctaacttga
     2521 ccacgtttga cttcgttgtg aatggtttga ggagctttag ccaatctcct agcgatttca
     2581 cgatttgaga gctcttcttg aagccaacgt tcaatcattc tacgttcagt tagtgtcaaa
     2641 tgtttacttt ttggtgtata atagtgttgc atctcagagt ctttctaatt gttgttgtgg
     2701 tgattacaat tatatctctc tgagatgttt tttgataccc ttaggtggct aacttcattt
     2761 tagaactttc caacctaaga cagcttactg tcttttcgat ataagcataa aaagcttgaa
     2821 tattcttata agctatgtta tactctggta aagttaatac tttaccagag tatgctgaca
     2881 aaggagattt atgctgatgt tttctggtat tcaattaaaa acagcacgtt tatcaaggca
     2941 tattagccaa gaacagctag gacagctttt aggagttaat aaaatgacta tttccaattg
     3001 ggaaaaggag aaaaatagac caaatcaaaa gcattttgaa gagcttgtga gcatttttca
     3061 attacctgct gagtactttt atcaagaaaa tcgtctttta cttccctata gtcagttaag
     3121 cgcctctaat aaagaaaaag ttatcagcta ttctgagagc ttacttgaac aacaagaaaa
     3181 aatatttgct ttaccagcta agaaaaagac actttaccct tatcgtgttt atgaaaggtt
     3241 gtctgcaggg actggctatt cttactttgg tgatggtaat tttgatgttg tgttttacga
     3301 tgagcaatta gattatgatt ttgcttcatg ggtttttggt gactctatgg agccaaccta
     3361 tttgaatggc gaggttgttc tcatcaaaca gaatagcttt gattatgacg gtgctatcta
     3421 cgctgttgag tgggaaggac aaacctatat caaaaaagta tatcgtgaag aaaatggtct
     3481 gcgtttggtt tcattgaaca aaaaataccc tgataaattc gcttcctttg atgacaatcc
     3541 gcgtattatt ggaaaaatca ttgccaactt tatgccctta gatgtataag ccttaaaagc
     3601 atgactgttg tacaaccaaa ctcattgcat gacattggtg cattattttt gaagtggctt
     3661 ctacttcttt gatttacttt tctgcattaa aaagcccgtt aaagtttttt gaagcttatt
     3721 actctacaaa gtacaaagat cataccacca gtttatttaa catgcacctt atggggcgtg
     3781 acggacttca caaaacgaac aaaacacatc gctaaaagat tttaccatct taaagttatg
     3841 tgttttttgt ataaaaactt atctatatgc ttgattaacc aactgagata aatagattat
     3901 tatttcatag agaagtttgt tatctaatcc aaataatcgt attatcctca ttacacgaaa
     3961 aaccgttaaa acgcaatatt tctttttcat tttcaatata tgcacacttt agagtttcat
     4021 aatcgttatt gcatattttc ttataataat caaacccttc tctacaaaat ccatatgaaa
     4081 gtccctttga caagtttaca ttaatatcga ctgaacagtt atcttcccat ctaatccaac
     4141 tttctccatt tttaggataa aatattctta ttgtatccgt tccatttttc tcttcaaata
     4201 atttaaaata attgcggtat aattcctcac ggtcacttat tatcctttta agttcctcaa
     4261 cattataacc atcacaatct gttggcagtt tatttttttc aagccactta tcaaccactg
     4321 ctattcccaa agaaattgaa aaatcttttt ctttatcaaa cttacacaat tccactgcca
     4381 aagtcaatac aaaattcctg tgaatattat cgtaattttc atcaaataat tgcctttcca
     4441 aacccacaat agatagccga ctaaatatgt atctccctat ttcttcgtca ataccttcag
     4501 tagccttaat agcttcttgg acaacattat tccagaaagc atttttatta cgctcttcta
     4561 taaaagtttt aagtttcatt ttgaaaatat cagtaatttg accaactgct ttatcaataa
     4621 cctgtgaaac aatattcttc atcattatga ttttctcctc gtatacataa ataattgtat
     4681 ctttgctata caattgtggt atctcttcaa tcaaccaata ttgttcttaa actattccct
     4741 caaaagcctt ccaccaaaac gatggaaggc ttttaaacaa ttcacctaaa ttcaacaact
     4801 cccttttgaa cttgctattt tagcttttta gtatcaaagc agtatcactc aagagttttt
     4861 tgtttccaca aaccgcaaaa acccactgtt tttaacgctt tcataacagt aacatatttg
     4921 tttctgttac tcccactcaa cggttgctgg tggtttgctg gtgatgtcgt agacaattcg
     4981 attaacgtgg tcgacttcat tgacaattcg aactgagatt ttctttagaa cttcccaagg
     5041 caattgggca aagtctgctg tcataccatc aattgaggtg atagcacgaa tagcgatggt
     5101 atagtcatag gtgcgaccat ctcccataac tccgacggaa cgaacacctg tgttaactgt
     5161 aaaatattgc cacacatcac gctcaagtcc tgctttagca atttcttctc gaaggatagc
     5221 atctgactcg cgaactgttt caagcttttc tgctgtgatc tctcccatga cgcgaatggc
     5281 aaggcctgga cctgggaaag gctgacgcca gacgacttca tctggcatac caagggccgt
     5341 accaagagca cgaacctcat ccttaaagag tgtattgagg ggttcgatta attcaaactg
     5401 catatcctct ggaagaccac caacattgtg gtgagatttt atcgtttgag cagtttctgt
     5461 tccagattca atgatgtctg tgtaaagcgt tccttgtgca aggaagtcaa cgcccttaag
     5521 cttgctagcc tcgtcatcaa agacgtaaac aaactcatta ccgataattt tacgtttttt
     5581 ctcaggatcc tcaacgcctg caagaagatc taaaaagcgc tttgaggcat caacacgaat
     5641 aatattgaga ccaaatcttc caccaagcat ttccataact tggtcacctt catttttacg
     5701 aagaagtcca tggtcaacaa agatacaggt taattgatct ccgatagctt tttgtaaaag
     5761 gacaccaaca actgaagaat caacaccacc agacaaacct agcaaaacct tacgatctcc
     5821 gactgtttcg cgaattttag caatttgcat gtcaataaaa ttatccattg accaatcacc
     5881 acgtccacca cagatagaga tagcaaagtt cttcaaaata tcattaccat agacagagtg
     5941 tcttacctct gggtggaatt ggataccgta gagcctcttt tttgtatttt ccatagcagc
     6001 gtaagggcaa tcgttagaat ctcctacaag atgaaagccc tctggaattt ctgtaacagc
     6061 atcaccatga ctcatcaaaa caagctgctc atctggagtg cccgcaaata atgctgatgc
     6121 agaacgtaaa cgtaatgatg attgaccata ttctcggtga cctgcttgac cagctgggac
     6181 taccttacct cctaaggtat gtgtgattag ctgcatgcca tagcaaatcc ctaaaattgg
     6241 aatccctaat tcaaagattt caggatcaat accaaaggca tcagttgcat aaacagaatt
     6301 tggcccacca gacaggacaa tcccgattgg attgatgtca cgaagctctt gcgcagtgat
     6361 gtgatggctt ttgagctcag aaaaaacacc aaactcccga atacgtcttg caatcagttg
     6421 attgtactga ctaccgtaat caagaacgat aattttttga acatcattca acattgaaat
     6481 ttcagtcatt ataacccttt cattatatac cagaaccttg ttagctgata gttttcaatt
     6541 aattgtagca tattttcact aaaaaggcat tagcttttca ggtgatgtga tgaaaaaata
     6601 agctttttgc agagacatta aaatgaatga cctcaactat cttatgtatg actactattg
     6661 tcagtcttag catgaaaaag ctgattgatg atgagtgttt ttggtaataa ttgggctgct
     6721 atttaggctg aaaatatgat aaaataaaac catcatcacc ctcaaggagt aaagcatgct
     6781 gccagcttat ataaaaattc atgacgctat taaaaaagac attgaaaaag aagtctggac
     6841 tattggtagt cgcctgccaa gcgaacgaga tttagcagaa cattttgagg tcagtcgcat
     6901 gacgttgcgt caggcaataa cactgcttgt agaggaggga attctagaaa ggcgtgttgg
     6961 tagtggtact tatgttgcca gccatcgcgt acaagagaga atgcgtggga ccactagctt
     7021 tacagagatc gtgaattctc agggacgtaa gccatcttca aaactgattt cctatcaacg
     7081 tcagctagca agtgatacag aaataaatca attgcactta gaagaatcag attacgttat
     7141 tcgaatggag cgcattcgtt atgcagataa ggttccctta gtttacgagg tagcatctat
     7201 tcctgagaaa tttattaaaa atgtcaaaaa aactgatatt acagagcact ttttccaaac
     7261 cctaacctca aacggttatg aaatcggcaa aagtcaacaa accatttacg cgaaaatagc
     7321 cagtgagcgt gtcgcctctt atctagaggt cgctaagggg catgctattt tagcattaac
     7381 tcaggtttcc ttttttacag acggtaggcc ctttgaatat gtgcgtagcc aatatgtagg
     7441 tgatcgcttt gaattttatt tagaaaataa ttaatcataa gcaatgatgt ttaaataaca
     7501 ttgataggaa gtggctcacc acttcttttt ttcaacactt gtcaagtata tcaatatttc
     7561 aagaacagtt attaaaacaa gctactatta tcctcatttt tgctctaaga aagtttcctg
     7621 ataaaaggct gatcgctatc atttaccact gttaaaaatg ctcatgatgt gataaaatga
     7681 agattatgga aattgaaaaa acaaaccgaa tgaatgctct ttttgaattt tatgctgcct
     7741 tattgactga taaacagatg aactatatcg agctctatta cgctgatgat tatagtctgg
     7801 ctgaaattgc tgaagaattc ggtgtcagcc gccaagcagt ttatgataat attaagcgca
     7861 ctgaaaaaat tctggaagcc tatgaaatga agcttcatat gtattcagat tatattgtac
     7921 gtagtgaaat atttgatgat attcttgcaa aatatcccag tgaccactat ttacgtgaca
     7981 aaatttccat tttaactagt attgacaaca gagattaaga ggagttatag ctatggcatt
     8041 tgaaagccta acccaacgtt tacaggacgt ttttaagcac attcgtggta aaaaaacctt
     8101 atctgaagcc gatgttcagg aagtgaccaa ggagattcgt ctagccttat tagaggcaga
     8161 tgttgcactt ccagttgtta agacctttat caagcgtata cgtaagcgag ctgttggcca
     8221 cgaaattatt gatacccttg atccaacgca acaaatactt aaaattgtta atgaggaatt
     8281 aactggtatc ttaggatcag aaaccgcgga gcttgataaa tcacctaaaa tccctactgt
     8341 catcatgatg gtgggcttgc agggagctgg taaaacgacc tttgcaggaa aattagccaa
     8401 taagctcatc aaggaagaaa atgctcgtcc attgatgatt gcagcagaca tctatcgtcc
     8461 ggctgctatt gaccagttga aaaccttggg acagcaaata aatgttcctg tttttgatat
     8521 ggggacaaat cattcagcag ttgatattgt tgccaatggt ttggcacagg caaaagagaa
     8581 ccgtcatgac tatgttttga ttgatacggc aggacggtta caaattgatg agaaactaat
     8641 gggcgagctt cgtgaggtta aagcactagc taaaccaaac gaaatccttc ttgttgttga
     8701 cagcatgatc ggacaagaag ctgccaacgt tgcctatgaa tttaacaatc agctcgatat
     8761 cactggagta gtgttaacaa agattgacgg tgatactcgt ggtggtgcgg ccctttctat
     8821 acgtgaaata actggtaagc caatcaaatt taccggaact ggtgaaaaaa tcaccgatat
     8881 tgaaaccttc catccagacc gtatgtcaag tcgtatcttg ggaatgggag accttcttac
     8941 cttgatcgaa aaggcaagtc aggaatatga tgagaaaaaa tcattagagc ttgccgcaaa
     9001 aatgcgtgag aatacctttg attttaatga ctttatcgag caattagacc aagtgcaaaa
     9061 catggggcca atggaagatc tgttaaaaat gattccaggt atggcaacta atcctgctct
     9121 agccaatatt aaggttgacg acaagcaaat tgctcgcaag cgtgctatcg tttcttctat
     9181 gacacctgag gagcgtgagc agccagagct tttaacacca agtcgccgcc gtcgcattgc
     9241 agctggatca ggtaatagtt tcgttgaagt caacaaattt attaaagatt ttaaccaagc
     9301 caaagccatg atgcagggtg tcatgtcagg tgatatgact aaaatgatga aacaaatggg
     9361 aatcaaccct aataacctcc ctaaaaacat gccaaatatg ccaggaggca tgcctgatat
     9421 gtctgccctt gaaggaatga tggggcaagg tggtttacct gacatgtctg cattgggtgg
     9481 tgatatggat atgagccagc tctttggagg tggtctaaag ggtaagattg gtcaatttgc
     9541 catgaagcag gccatgaagc gtcaagctaa taagattaaa aaggccaaga aaaaacgaaa
     9601 atagactaaa agaatggttg ccttgtattc tgcctctaat cgttagatgc tattctaatt
     9661 tggagtgcag gtcagtagcg accatctttt ttataaatac aatcactaga tctttggttc
     9721 taaccattaa acatgatatc atttcactat tagctgttag tgcctgtgct ttaattgctt
     9781 tctgatctta tatagcaaat tagccaagtg ataaaaagga ctgattgcta ggttgaattc
     9841 tccaataaac tcttcgatag ttggactgaa attggactta aatgctgtca atccgtcctt
     9901 gaaggagcca tcaatgccgc ccatattcgc ccaagctata tcatcatgat aggcatccat
     9961 aaagacttta ggataaagca ggtactgagg ataaaacttt ttaaagtcat cattcatgcc
    10021 agcatagagc atttccatcg tgttgccata tgaaatcgat aaaatgcccg caatgacaac
    10081 ctcatctgga tatttatcca agaagccctt gaattctgat agataacgct gaagcgattg
    10141 cttttgatct gttagtctag ccagtcgctt tttttgatgc gcttgcgttt gagcaagctc
    10201 ttgttcaaca gctttcagct gaagctcgta attcttgagt ttttctggaa gattaacctt
    10261 tgctaaatgc aagtaagcat tgtcgctata aatcgtcatc agctgtctaa aataagcttc
    10321 gtttcttaga gcaactcctt ttctcttttc agttaaagag ataagatcag caaatgtatg
    10381 gagatcagac tgattacctc tataagctat cacgccacgt tgcctagcat ccttcatcaa
    10441 tcgcttggta tgcttaggaa aggacgcttc aatatcagca ttagtgtaac aatttgcttg
    10501 aaaacgcggc tgaatagtat cagatagttt ggttgttggg cctgtccaat gggcaccaaa
    10561 ttgctttaaa tgcttaataa tggccagagc cttgggatta tcaggtgctt tctcaccaag
    10621 ctgatgctgc tttagcagaa tcataggatc aaatttaatc aaaagagctc tttttttctt
    10681 accatatgcc ttcaaggttt taatcgtaaa tgccaccaga tcagcattgg tatagtccat
    10741 cactggacct cttggaatat aaatcatcgt cataccaaac ggcaaaggct taatcagcaa
    10801 ggacatagaa gccacctgat tatctccctg aaaaataccg atgcgttcat tttgccactg
    10861 atttttaaca gctgcccatg agctgctctg caagaggtta acctgctggt gctgtttgac
    10921 aaattggtca tgctcctgcg ctgaaatacc aatttttgaa taaaaagcta cgtttgtcat
    10981 catatttcct cgtctttacg tgtttgaata tctgatcttg aaatagatct gcttctactt
    11041 aatttattcg aaaaatagtt tgaaaaataa ttgctttttt tgattttcaa tttgattatt
    11101 tttagctgct caaatgaata atcgatttcg gtttaaataa gtttaaaaaa taggactaat
    11161 tcctaatgaa attaggaatt agtcctacta cttttatcta tttatcagtt acccattaag
    11221 ccgtcaatca atcctctaaa gaaatcaata atttgctgaa ggattccttg tccagtcttt
    11281 aaggcttcag tagcatcaaa gttcacgttg atatttttaa aggtagatcc ggccttttca
    11341 acaatactat cctttaaagc attcagcgtt ttggtgaagt tttcattgga aatcacgcca
    11401 ctatttgaga ggttaagcgc gaaattgata ataaggttaa tctgatcagg tgttactgcc
    11461 ttcgttaacc cataatggtc taaggtttct gttacaattt ggcgaacctt ttcctcatta
    11521 accccctctc cagcctttgc gacagcagct ttaatatcag taagtgcaac atttagctta
    11581 tctgcatcat agcctgtttt acctgcattt tcggtattga tattagatag agttgatagc
    11641 tcctcttgtg ccagcttctt gctttcctct gggactttgg caccattttt ttcgagtgag
    11701 taataaatac cggccaaagc tgattctcca gtaactggga ttggtgcagc tacagtaata
    11761 ttggcatgct caatgcccaa ggtcacagcg gcgttacgat acatatcttg cgtcacctta
    11821 gtaatatttt caggtgttac aatagttacc ttaagcgttt ctttagctcc cagcttttga
    11881 atcctaactg aggaataaag ctgtaggctc ggatcatctg ctacattcat gatactagca
    11941 taggcagttg tatttagggt gcttaatttg ttatcagaag cactattgta gtgaagcaag
    12001 gccaaggttt gctctctttg ctcagcagac agtgaatagc ctaaaacgta atcaggctga
    12061 acataggttt catcaattac ctgttgaaca ttattagctg cagcgtgtac tgtttgaagc
    12121 ataaataccg aagccaaagc catactggct gctattaatt tcttttgata agtcattttt
    12181 ctacctcttt tgtgttataa attttccttt acgagaatcc tccagaaaag acgattaaag
    12241 ccaaagtatc taggtgccta gtaagaccgt tttacttagc tctgcaaagg gcaatattcc
    12301 tagtcttttt caaaatctaa cgcctctatt gtagcatttt tacctcaata agacgattaa
    12361 aaagctgaaa caaagcatag ctagaatggc caagcactat ttttacaaca aaaaaactag
    12421 tgcataatgg cagcttagat gtagctacta tcactagtcc aatgattatc ttatgcagca
    12481 accagtcttt atgatctgag gttttcttga tggttattgt cctttaaata gaaataataa
    12541 tgatcatcag ttttgatgac atagccattt ttaacctcat taatcacgtc cttttgatca
    12601 aactggtagt ccttaggcgg taataactct gaggaaaaaa ggctatcata aggcacctca
    12661 ccattgtaaa aatggtaatg gtcaccatga gaggtaacaa aaccatcatc cgagatagac
    12721 acaataattt gctctgctgc tatcccctct tccttgctaa cttcattagg acttttgtca
    12781 gtctctttct ttaaggcttt gcaccttttt tccaattgat gagatgattt tagcttcttg
    12841 cctgtgctat cttgggcttt aaagtcacaa gcggacaaag gaaataatag taagatagtc
    12901 aataacgata aataaacttt tttggtcatg tttcactctc caatacacga tatagtgttt
    12961 ctaaatttat ttttaaatgc tctagataag ttttttgatc agctggaacc acctcaagcg
    13021 ggcttaggat atcaattgct acaccgttac tttgagccaa ggttttggct agcttatctg
    13081 aagcattttc ttcgacgaaa atcgtcttca catcatattt tttgataaag cggtcaattt
    13141 gagctaattg gcgaggacta ggctcttgct caggagatat ccctgcaatt cccaattgct
    13201 ttagaccaaa tctcttagct aggtaggaaa aggctgtatg ctgtgtcaca aaggttttcc
    13261 tacctagaga ttcaaacttt tccttatagg tcttcactaa tttttgagcc ttagccttaa
    13321 aacgcttagc attttgcaaa taaactgcct tgtgagcagg atctttttga ctcaataaag
    13381 ctgcaatctg ctctgcctct tgactagcta agataggatc agtccaagtg tgaggatcat
    13441 acaaggcatc ggtattcatt ccttttttta tggtgaggtg ttccaaacct tgaaccttgt
    13501 ctaatgttag atgtgatgtt ccctccatga ctgctagtcc ctttttttct agctgtggcg
    13561 ctaaatccgc agcccaggct tctaatatct tggaatggta aataaagaca tctccatcgt
    13621 aaatcctagc aacaactgtc ggacttggct catacgagtg tatgctagtg tttttggcaa
    13681 tgacctgaac atcatttaaa tccccgcaaa tctccttagt catagcataa atagggtaga
    13741 agcttgtttt tatgaccaaa ccggccttcc tactgctaga gctctgatga caggctgata
    13801 gacccaaaag cactactagc agccctactg cgacaattgt tttcttgaat cctctaatca
    13861 tatctactct cttaactagt taatgaccta aaaaggatac catgatttaa ctgaaatgtc
    13921 aatattttat cattttagcg cacgacgtac acgcatgaag aaaatgcatg taagcctttt
    13981 ttagccccat gcatttttta atctatttct agcgttttga cattgcaata tcatcagttt
    14041 gtcaatttca atgtgatgat ttcatcacat tttgctaaaa aggccatagt gatgatgaaa
    14101 aaacgctacc agaaagcgta aatgtcttct tgcttttgtt gtgattttag tgaatcgcct
    14161 accaactgaa ctgaggctgg cttaaccatt tcctagccgc catcaaaagc ctgcttttta
    14221 tttaacaagc ttactcaagg aaggtgtgac tccttttttg aggtgactga gccatgcagc
    14281 cgtcttagtt atgattaaca gcttatcttg gcatttcatt catgtaattc cagtggcagg
    14341 ccatcaggat caaaaaagaa ggtcatcttc ttcccagtat aatcatcata cctaagaggc
    14401 tcgacagcaa tgcccttagc cattaattga tcaatataag cttcaatagg cttgacatga
    14461 aaagctaaat gacgaagccc acaggcctct cggtcgtatt cgggtctacc gatacgctta
    14521 ggcggtgcct gataagccgg atcagtcttt ttgttgccaa aaatctctaa ttcaatggct
    14581 ccacatttca aatccaattt gtaatcatgt ctctcaggcc gatgattttc acgaataatc
    14641 tcaaagccaa gcttattgac ataaaaatcc ttagagacct cataatccga aacaatgata
    14701 gcaatatggt gaatagcctt aagttccata tgatttagct cctttatcaa atgaaaaaaa
    14761 gtgaaataaa gtaatatcaa cattacttta tttcacctct cctagcgacc cttgcctaga
    14821 ttgggcttag gttgacatct ggttgtaaga atgattaaag gccttcaaaa cattgtcagg
    14881 tgctttgtta aactcatact cgtttttgat tgctcctttg acaatgattc gctctgttgc
    14941 ctcataatcc gtacaggtga ccaaggttac ctcctttagt cccggtgtgt cgttgataac
    15001 atctattctt tcaggtgtga ccgtaaagac agcattgatc tcatactcgt aaatacgctc
    15061 cttatctgta aggtaaatag acatcccttc ttttgctctt tcaagcggtg aaaatagcat
    15121 ctcagaggag cctgttagtc caaaaatatg atgactggct aaggagtaat tgttttctcc
    15181 tcccataact tggtcctctt tcatggtacc agcaccatat ataagctcgg tatttccaag
    15241 tcctttaaag attggtaggt taataccaag ctctggtatg gcaatacctc ctattactgg
    15301 aagctgctga gcgtccattt gggcctgtag gacactttcg gtgctaaccg gctgaactgc
    15361 ttgaaaatca aagcttgact ttgcttcctt attcttttta atcgtctttt ttgaaacctt
    15421 tgtgacttga tatttattag aattccaagc aatcaaggta tttctaatgg gcttgttaaa
    15481 taacaaggct aagcctatga ttaataataa aacgactaga atacctctag caaaggacat
    15541 ctttcttcgt ttttgccttc tcctatgggt tctttttgcc attcatttac tccttgctag
    15601 aatttattgg tgcttctgct aaagctgtat cagtctgagt gattgctgtt ggatcgttgt
    15661 cttcagcttg taccaaggta aaggtaacaa tcttagaatc tgtatctagc ctcatgacct
    15721 taacaccaag tgttgaacgg ccagtctgag agatgcttga gacgttggta cgaataatca
    15781 cacccttcgt tgtgatcacc acaatatcct cattgccatc aacagtcatt aggccagcca
    15841 actggccatt ttttgcggtg atattagctg ttttgattcc ctttccacct cgacccttag
    15901 ttgggtattc ggctgcactg gtacgcttac catagccatt ttcggtgatg actaagacct
    15961 cttgcttgtc attgatacga gaagctccga caacccaatc ttcctcacga agcttgacac
    16021 cacgaacacc cgtagcgcta cgccccatgc ctcgaatggt agcttcatta aagcgaacag
    16081 aataacctga tcttgttcca atgataatat cttcctgacc atttgtcaag agaacattaa
    16141 tcagctcatc tccttccttg agattaaggg ctcgtagacc attctgacga atattgctaa
    16201 actctgatac ctcagttcgt ttgacaatcc cttgctttgt tgtaaagaag aaatatttat
    16261 caagaatgtc ttctttttta gcattgataa tggtttgaat ggtttcacca tcatctagct
    16321 ttagtagatt gataacagga agtccttttg cagcacgtcc atattctgga atctcatagg
    16381 cctttaagcg atagacgcgc ccaaaattgg taaagaaaag caatgtgtca tgtgtacttg
    16441 ttgagacaag ctcacgaaca aagtcatcgt cattgacacc tgttccttgc acaccacgac
    16501 caccacgctt ttgagatcga aactcgtctt gagcaaggcg cttaatgtag ccattgtttg
    16561 atagggtgat caaaacatcc tcttcctcga tcaaatcctc atcttctaat gacagtacct
    16621 caccaaccat caattctgtg cggcgaggat tagcgtactt gcgcttgatc tcctccattt
    16681 cttccttgat gatggcttcg atacgctctg gctttgccaa aatatctgcc aaatctgcaa
    16741 tcaaagccag taggtcatcg tattctgatt gaattttatc acgttccaag ccggtcaaac
    16801 ggcgaagacg catatctaaa atggcttgac tttggcgttc agacaagtca aaacgagaca
    16861 tcaattctgc ttgtgcgata atatctgtct cgctattgcg gataatggca ataacctcat
    16921 ctagatggtc aagagcgatg agtaagccct ctaaaatgtg tgccctagct tctgccttgt
    16981 ccttgtcaaa ttgagtcctg cgtgtaatga cgtccttttg atgtagaata taattatcaa
    17041 taatctgtct cagtgacaag attttaggaa taccgccttc aatggctagc atattgaagc
    17101 taaagtttgt ctggagactt gtcaatttga ataggttatt taaaatcaca ttagcagatg
    17161 catcgcgacg gacttcaatg acaaatcgta ccccttgtcg gcttgattcg tcacgaacag
    17221 ctgtaatgcc ctcaatccgc ttttcttggg ctaagcgaac aatatgctca tggacctttg
    17281 ttttattaat gccataaggg aattctgtga cgacaatccg ctcccgtcct gtactagtgg
    17341 tttcaatctc ggtgcgtgaa cgcaaaacga ttgatccctt accagtctca taagccttat
    17401 gaattcctga acgtcccatc accaaggcac ctgtaggaaa atccggccct ggaagaacct
    17461 ccattaaatc tctggtagtg cagtcaggat tttccatgac catcttaaca gcgtctatag
    17521 cctcagctaa attatgaggt ggaatattgg tagccatacc aactgcgatt ccggtggcac
    17581 cattgaccaa taaattgggg aagcgagccg gtaagactaa gggttctctt tcattaccat
    17641 catagttatc ctgaaagtca acagtatttt tattaatatc ctttaagagc tctagcgcga
    17701 ttttgctcat acgagcctca gtataacgct gagccgcagc accgtcaccg tccatagaac
    17761 caaagtttcc atgaccatcg acaagcatgt gacgatagct ccaccactgg gccatacgga
    17821 ccatcgcttc atagatggac gaatccccat gtgggtggta cttacccatg acatcaccgg
    17881 taatacgagc agatttttta tgtggcttat caggtgtgac gcctagctca ttcatgccat
    17941 aaaggatacg acgatgaaca ggctttaagc catctcgtac atctggaagt gctcttgcta
    18001 caataacgct catagcataa tcaatgaaac tcgttttcat ctcacttgtc agattgacgt
    18061 caactaaatg tttatcttgc atgtaaggaa tgctcctttt ctagtcaata ctcttttaat
    18121 tataccataa aatccttatt ttttctggtt ggaaacgcta tccgaaaaca attttcataa
    18181 tttggtcgaa tatcatgaca aagacattac aatgtgttaa aataagatcg tatgagcaat
    18241 ttgctctaac taaaatgaag gagatgttta gaaatgactg caactaaaca acataaaaaa
    18301 gtcatcttgg ttggcgatgg tgctgtaggc tcttcttatg cctttgcact agtaacccaa
    18361 aatattgccc aagagcttgg tattattgat atttttaaag aaaaaactca aggagatgct
    18421 gaggatttaa gccatgcgct tgcctttacc tcccctaaaa agatctatgc tgctgattat
    18481 gctgactgtc acgatgctga cctagttgtt ttaacagctg gcgctcctca aaagccaggt
    18541 gagactcgtc ttgaccttgt tgagaaaaat ctacgtatta ataaagaagt agttactcaa
    18601 attgtggcct caggctttaa gggaattttc cttgttgctg ctaatccggt ggatattttg
    18661 acctattcaa cctggaaatt ctcaggtttc cctaaggaac gcgtcatcgg ttctggaaca
    18721 tcacttgact cagcacgctt ccgtcaggcg cttgctgcta aaattggtgt agacgcacgt
    18781 tctgttcatg cctacatcat gggtgagcat ggagattcag aatttgctgt ttggtcacat
    18841 gctaatgttg caggggttgg attgtacgac tggcttcaag ctaatcgtga cgttgatgaa
    18901 caaggcttgg tagacctctt tatctctgta cgtgacgcag cttactctat tatcaataaa
    18961 aagggtgcta ccttctatgg tattgcagtc gccctagcac gtattacaaa agctatcctt
    19021 gatgatgaaa atgcagttct tccactttct gttttccaag aaggccaata cgaaggcgtt
    19081 gaggattgct atatcggtca gcctgctatt gttggtgcct atggtattgt tcgtccagtc
    19141 aatatcccat tgaatgatgc tgagcttcaa aaaatgcaag cttcagcaaa ccaattgaag
    19201 gctattatcg acgaagcctt ctctaaagaa gaatttgctt ctgctgctaa aaactaatta
    19261 aaaaatgaat aaacctccag gtgttagatc ttgctctaac gttttggaat cactacaaaa
    19321 agcctaatcc aatcggatag gcttttttca tgcgtctaac agcgaggtgc aagacaaagc
    19381 acgttttcat taagcatcgt gcgtgctatg cttatattat agtcttaagt cacaaagaaa
    19441 gacaaccagc tttataagct ggctgcctat taacctatta ttcagcacca agtgctgcca
    19501 ttgtaatgta gttatatggt ttattaaagt gtggcaagaa gaaaatatca gtcaaagcta
    19561 atttctcaat ggtcactcct tcttggatag caagtgagaa catatgaatt cccattgaaa
    19621 tatcttcatg tgaggccatt tgagcaccta gaatacgacg tgattcttta tcgtagacaa
    19681 tcttaatggt tacttggaag ttaccatgct cgataaattc tggtttttga ttgtcagtgt
    19741 attctgttac tgctgcatca aagccaaggc attttgcttt ctcaagggtt aagccagttg
    19801 ataccatgtg caagccgtag atagagatac catttgatcc ctgcacacca ataccctcaa
    19861 gagctgtgcc acaagcgtta tgagctgcga caatccctgt acgaacagca tttgaagcaa
    19921 gggcaatata attggtatcg cgagttgcat tgtcatagat ggttgcacaa tcaccgattg
    19981 cataaatccc tggaatagat gtttcttggt gtttgttaac aaggaaggca ccattacgga
    20041 aaagctcaat cttgccagca ccaagagctg tatttggacg gaagccaact gcaaggataa
    20101 ccatatcaac atcgtattca ttcttatcag tgattagctt ttcaaccttg ccatcaccag
    20161 caacctcttt gacagtttcc ccaaaggcca actgaatacc atgctcttct aggtttttag
    20221 acatgacatc tgtcaaatca cgatcatagt agcctgctag acaagtatcc gcaacatcaa
    20281 tcagaataac ctctttgccc ttacgttgga aggcttctgc aagctctaca ccaatgtagc
    20341 ctgcgccaac gactgcaacg cgcttaatgt ctttgttttc taatttcgaa atgacatctg
    20401 ctgaattttg gtacaattta acgaattgaa gattttcaag tgttgcttca aactctaatg
    20461 agccctcttt gatttctgca cctttaattg gtggcaagat aggctgtgaa ccagttgcaa
    20521 aaattaattt gtcatatgac tcaacatgct ctttgccatc aacaagggct gtcactgttt
    20581 tagcatcgta gtcaatagat tgaactggtg attccatgta aaccttagca ccaagggatt
    20641 ctagctcttc cttatttgag tagaataagc cctctgggcc agaaatttgt tcgccaatcc
    20701 aaagtgccat accacagcct aagaatgaaa tatttgagtt ttggtcaaat acaacaatct
    20761 cattagcatc accatagttt gttaacatag tcttgataca tgccgtacct gcgtggtttg
    20821 caccgataac aacgatttta ctcatatgat tatgttcctc atttcacaat ttatattagg
    20881 tctctattat aacacaggga aaaagcgctt ccaactaaaa tgctcatctt tcttgctttt
    20941 ttataccgtt ttttagtcaa taaataagac agcctatcat ttgttgaagg gtcgtacaaa
    21001 gaccggtttg cttcagttaa gtccagacga cgttcttatt caactatttt cccaaattca
    21061 ttacatgatt aagaccattt tttgtcgtta acttctaaaa aagactcata agctcaatca
    21121 ggtaaagatt gacatgtacc tcttgagcat aataaatatt gccgccgttg caataaagct
    21181 ttccaccaga gaggagggct aaggggtggt aataaaaata ggtttttcca gtagtatttc
    21241 ctaggctggg tgcaacgaca atcctagaat aggtagtggc tagctcaatt gaatgctgac
    21301 cgccattttt agcaacgtaa tcaatatagg cggttccaaa attgtaagct tgaacagctg
    21361 tccaagggtc tacgccggct ttttctgcta aagctaaatt gtgagatagc aatctgacac
    21421 catactcaat gctagattga ctatcagtga tcgaatccct tatgccagag ctgctttcgc
    21481 ttgactgcat aacgtcaact tctcctccct tagtttccgt atatatcata gctagtacca
    21541 gatcgacgtc tgctttgtta ccgttttctg ctaaaatacg ctctactgtc ggcttgtatt
    21601 gtaggactct gtgcacattc ttatgaatgg taactgcttc gtacaggcaa aaaatgagga
    21661 aggctaatcc taagatacgc tttaacactc taaacattta gttatttttg atatcctcta
    21721 tattttttat caatatggaa taggttccgt tgtcattcaa gataaactct accgactcgg
    21781 catcttgata aaccgcatta gggacaagaa gctcaattcc atttgacagc gacagctttt
    21841 gcgtctctag cttttttagc tgtctagaat gatcaatatc actgacctga attggttcgg
    21901 gaatcatttc cttgacctga tccacaaagg ttaatcttgc agtcaaattt tggtcaaaca
    21961 attgatccgc tagcttttct ggagataggg ctgtttcttc ttccagattt ttagccagtg
    22021 ctactttcat ctttgattga aaagcaaagt catcttggtt aaaattctca gcaacctttt
    22081 gagcggtctg ctcaagcatt tgaatagatt ttttgacaga ttgctccggt gttaccttta
    22141 gcagcttctc agaaaaataa tgagcaaagc ttccattgtg cttcatgcgt ttttcgatta
    22201 agtagtaata gcctgtttga cggttaatga ccaaggcttc atcgggtgcc tgggtagggc
    22261 ttggcaaatt attttgcgtg atcgtaatag gattttcatg atcgtctgat agatgggcaa
    22321 aatgctcttt tagggcaatg cgtaaaaagg ccagataagg ttctcctgcc ttatcaaact
    22381 gaataaaaac caaatcgttt gtcttttgat gttcagaagc gacaaattct tccttccaaa
    22441 gcttggcaat tgttaccgat gtttccaaaa gatctgtact gattgtggta aaaaaagcat
    22501 gatcagcttc taattgccca cgtttagcgt cgtcagaaaa aaccttggct aattttttgc
    22561 gaaaatactc atcaattctt ggtgttatgg ccactaaagc atctgacagg atcagctcta
    22621 tgtcatttgg cgtgaattgg tggatcacaa ttccttttat ataaatatct agcattgtta
    22681 gttcttcttg tataatggga aggcgtcagt caatcggcga acctcataac ggacctcttc
    22741 aaggatttca ggctgatggt ggttaaccaa ggccttgata atcaaatgag caatagtcct
    22801 actttcgtct actcccattc cacgactggt aatggcagcg cagcctatgc gaatgcctga
    22861 tgttttaaag ggagataagg tttcaaaggg aatagcattt ttgttaaggg taatattaac
    22921 ctcatcaagc agggcttgag caagcttgcc attttcaatc accttagtca catcaacaag
    22981 gaaaagatgg ttatctgtac cgcctgagat cagacgaaaa cgatcatcct tggcaaaaac
    23041 ctctgccatt gctgctgtat ttgctataac agcccttgca tagtctgtaa aggcaggatc
    23101 aagcgcctcc ttaaacgcaa cagccttcgc tgctatgaca tgctccaaag gcccaccctg
    23161 tagaccaggg aaaatagctg cattcatttt ccttgcaatt gcttcatcat ttgtcaaaag
    23221 caggccgcca cgaggaccac gaagggtttt atgagtggtt gaggtcacaa tatgagcata
    23281 aggtactgga ttttgatgca gacctgctgc aaccaagcct gcaatgtgtg ccatatccac
    23341 catcaaagag gctcccacct ggtctgcaat aaaacgaaat tgctcaaaat caatctgccg
    23401 agaataggct gaggcacctg caacaatcag cttaggctga acagcctcag cttgctttag
    23461 gatagctgcg tagtccagcc tttcagtttc cttatcgaca gtgtagccga caaattgata
    23521 ggtttttcca gaaaaattga caggtgagcc atgtgtcaag tgacctccag ctgccaaatc
    23581 catgccaagc acagtgtcac cagcattaat cagtgccata taagcagcag cattggcctg
    23641 actaccagaa tgaggctgaa cgttggcata ggctgcacca aagagctttt tggcacgctc
    23701 aatagcaagg ctttcaacaa tatcaacata ctctgtgccg ccataataac gcttgcttgg
    23761 atagccctca gcgtatttgt tggtcaaaac agagccttgt gcttgcataa cagcctttga
    23821 gaccatattt tcagaagcaa ttagctcaat attatgctct tgcctgtcct cctcggcctg
    23881 aatagcctcc caaagctcct gatcatagtc tttgtagttc tcgttgttaa acatcattat
    23941 tgtctcctct ataatagctt cataaatcgt aattgtgtct tatcatctac atagctcagc
    24001 ttacggtaaa aggcatgtgc ctcggtcctg tgactagcag aattaagtcg aataaagctt
    24061 gctttctcct gcctagcctt cttttctaaa gcagctagta agcgacgacc gatacctcta
    24121 ccttgatggt ccggcttcac tgctaaagcc aaaatattaa agcctttttc cgagtaaagc
    24181 gattcgtagc actcggcatg caaatagcct aagagtagat tggtcttagc atcagcatag
    24241 cccagcaaat aatgatgctt atcgaatctt agtttttcca attggcttgt tgtcaattca
    24301 agagagacct tgtatcccaa ggcttgatca ttaatgtcac aaatagcttg acaatctgtt
    24361 tgatctagtg gtcttagcat agccttacct cctctaaaat ggcagctctg gaaccttagc
    24421 taataattgc tccttagtaa tagcaccttg tcgtaaaata ctgaccttag gtgatgataa
    24481 atccaaaata gtagaatcct tccctgtcaa ataggcatca tcagcataac catcaatctt
    24541 tccatcaaac gccttgacaa tgtcgttaaa gcattttcca ctctttgagc ctgataggtt
    24601 agcagatggg ccaatcaagg gacccgttgc tctgataatt tcagctgtga gagggtgact
    24661 aggtagtcga aagccaactg tttttagccc agaattaatc caatatggcg tcttggcatt
    24721 ggcttttagg ataatcgtaa gcggaccagg taaaaaagcc tcgtacagct tgttaagata
    24781 ggctggctgc tgcttagaaa aagccaaaat actctcaaaa tcagccacat taaggttcat
    24841 agccttgtca cgaggccttt ttttgagacg ataaacagca ttaacagcct cttcatttaa
    24901 ggcctgagca aaaagaccat aaactgtctc agttggtaaa ataagagctc caccagcctt
    24961 aattgtctct atcaaatgtg ttatcatcaa caaccaccat tctttcttta cccagcatat
    25021 ccttaagcac tctgatacgc ttttgaggga aacgcttgga caagagtctt tttaagccct
    25081 ctccctgctt gtagcccatt tcaaaataga gcttgccact tgtcgtcaaa taagcactag
    25141 catgttcgat aatgcgccgg taaatagcaa atccattttc agcagcaaat aaggctaaat
    25201 gtggctcaga ttgataaaca ttcaagccaa cctcgtcctt atcctcatag gcaatatagg
    25261 gagggttaga gacaataatg tcaaactgcc ccgatagctt gctaaaaaga tctgactcct
    25321 caaaggctat ctctacatga tgatctaaag cgtttgagta agcaaggctc aaagcatcag
    25381 ctgaaatatc agaggctgtg acctgccagt taggccttgc tttttttaaa gcaatagcaa
    25441 tagcaccact acctgttcca atgtctaaaa cggatttgcg agtagcgtca ttttccttca
    25501 agataagctc aactaattct tctgtctctg gtcttgggat tagcacgcgc gaatccactg
    25561 caagcaccag atccctaaaa taagccctgc ctgtgatata ttgtggcgat acatgctggc
    25621 taagcgctaa aaaaatccgc tctaataagg cttgatcctc tgaagtgacc tcttgatttt
    25681 gatgaagcaa aaagtcaagg cttgtccact gctttaattc tttaaaaaca taggcgaggt
    25741 tttcacgatc ctcacctatg ttttctagcc tgtcttcgta ggctcttagt tgcttagcat
    25801 agttcattgg ttatttagcg attctaattt ctgagtttga tcatatagca ctaaagcgtc
    25861 aacaatctcg tctaactttc cagacaaaat ggtgtctaat ttttgcaggg ttagaccgat
    25921 acggtgatct gtcacacgat tttgtgggaa attataggtc cgaatccgtt cagaacgatc
    25981 acccgtaccg atagttgatt tacgctctgc gtcctgctcg tcctgtgcga tctgtgcaaa
    26041 atgatctgct acacgtgctc gaataatctt catagccttg tcacgattct tttgctgcgt
    26101 tctttcctct tgcatctcaa ccttgatatt tgttgggaga tggacaatac gaacagcggt
    26161 tgccaccttg ttgacatttt gtccgccagc accagaagca tggtaaatat caatacgaag
    26221 gtcctttgga tcaatgtcgt actcaacttc ttctacctct ggcatgacta agacagtcgc
    26281 agttgaagta tgcacgcgcc cttggctttc agttaccggg acacgctgca cacgatgagc
    26341 acctgattcg tattttagct tggaataaac agattggcct gaaaccatag caacaacctc
    26401 tttaatccct ccaacaccat tataggaagc ctccattacc tcaaagcgcc agccttggct
    26461 ttcggcaaat ttttggtaca tggctaagag atcaccggca aatagagcag cctcatcacc
    26521 acctgcggca ccacgaattt ccaagataat atttttatca tcatttggat ctttgggaag
    26581 cagcaaaagc tttaacttgc cctcataggc ttccttggca gacttggcct cttttagctc
    26641 ctccttggcc atctcttcaa tgtcaggatc gccgccggct tccttaatca tctcctcagc
    26701 gtcatcaatg gattggataa tagccttata ctgacgataa gctgctactg tttctcgtgt
    26761 gctagcctct tcctttgaca gagccataaa acgtttggtg tcagaaacaa cctccggatc
    26821 acttaataat tcgcctaatt cttcataacg gtcctcaacg gcctgtaatt gatcataaat
    26881 attcattagg gggtattctc tcctcttttt acttgttatt agttatgatt agattggtgg
    26941 gtgaaaataa tgcttgcgac aaactggaat ataggtctca ttgccaccaa tttgaatctg
    27001 tgctccctca taaacaggct taccatgttc tgttcgcaat accatagttg cttttttgct
    27061 gcaatattga cagatagttt ttatctcatc aatcttatca gctagcagta acaggtattt
    27121 ggagccttca aacaattcat tttgaaaatc atttttcaag ccaaaggcca tcactggaac
    27181 atttagctca tcaaccacac gtgctaaatc atagacattt tgcttgctta aaaattgaca
    27241 ttcgtcaatc aagacgcaat agggcttctc ctgcaattca gcaataaatg caaaaatatc
    27301 catatcattc gaaattggta cagcctcacg acgcatgcca atccgactag aaacaatgcc
    27361 aaagccatca cgtgtgtcta gcgcacttgt cataatcaca acaggcttcc cctgttcttc
    27421 ataattgtgt gctaccttca agatttcaat ggtctttcct gaattcattg ttccatattt
    27481 gtaatataat tgagccaaaa tggagattcc taccttcttc ttttatccta cttattctat
    27541 catatttgtc cctatttggc gattgcctta tctgaaaatc ttattttcac aacagctaaa
    27601 tcctgtgctg ttgagctaag gttaggcttt ttggagctga catgctacaa tagaggtatc
    27661 aaaaaaaagg agattgacta ttatgccatt tgtaacgatt gatctgtttg aggggcgcag
    27721 ccaagaacaa aaaattgccc tagcgcgtga ggtgacagag gttgtttctc gtatcgcaca
    27781 ggctccaaaa gaagcgattc atgttgtgat taatgacatg cctgagggga cctatttccc
    27841 gcatggtgag atgaaaacca aagcctaatg cctaagtccc acttatctag gtgggctttt
    27901 cctatttgaa aaggagggcc tgatgatagc tactgatcag atcaagatga tgggaacaat
    27961 cattgatatt tacattgact catcaaaagc aaagcagcaa gcagctacta tccgagagct
    28021 actaaccctt tacaatcacc gtttttcggc caatgacgac agctctgaat taatggcaat
    28081 caaccatatg gcaggtattc agcctgtgcg tgtgcattca gatttatttg acttaatctc
    28141 aatcggaaaa gagcacagct tggcttatcc aagcaacctt aatatcacac ttggtccttt
    28201 agtgcaaagc tggcgcatcg gcttttcaga cgctaagctt ccagatgaag caactattga
    28261 tcgcagacta agactaacca atcctaatca tatcatctta gatcagggcc ttggaagcat
    28321 ttttttgaaa gaaaagggca tgtctatcga cttaggtgcc ctagcaaagg gctatattgc
    28381 tgataagctc atggcatttc ttatcaaaga cggtatcact gctgctctta tcaatctagg
    28441 tggaaatgtc cttgtgcatg gcaccaacaa gcaacgacat aatggcttgt tttacgttgg
    28501 gattcagcag cccaatcaaa aaagaggaca gcatgtcggt gtgattaagg ttaacaataa
    28561 atctgtggtg acctcaggaa tcggcgagag acaactacag attggagaca aagcttatca
    28621 tcaccttctt gatcctcaca acggctatcc tatcaagacc aatatggcta gcctaaccat
    28681 tgtcagccaa tcctcacttg atggtgagct atggagtagt cgtctttttg gcttagagca
    28741 ttcctttgtc ctaagtcagc taaataagct gcctgaggtg gagggcatta tcatcaccaa
    28801 agatggtcag gttactatct cagacgggtt acagggagtc tttcggctac attataagca
    28861 ctaaaaaatc agctaagtga atacctagct gattttttag atacaaggtt tactccaaga
    28921 gaccttcaat gccaagtcat aattgcctgt ctaacgactc atctcaataa gaagaaagca
    28981 gtcaaatctt gatagtctct actaagatcg taaagctaca aaagcgattt acccatgact
    29041 caccataatg caaagactgc attatcacaa gccaattgct actgaaacaa agctggtgta
    29101 gctatacaaa caaaaatgca gttatcaggc atcagcctct aaaaagctta ccgttccatt
    29161 gtcaaaatgc ttaatacgag ccaatgaggt gacctctact cccaaatcct caagcaattg
    29221 ccgtccagcc tgaaaggatt tttcaatgac aatgcctatg ccaacagcct tggcccctgc
    29281 ttgctgaata atatcaatca agccctttgc cgcttgacca ttagccaaaa agtcatcaat
    29341 aatcaaaacc ctgtcttctt ttgatagcag ccctcctgca atagaaacag tgcttgtcac
    29401 ttgtttggtg aaggaataaa cctctgctgt taaaattccc tctgtcatcg tgatattttt
    29461 gtgctttttg gcaaaaatca tcggaacctc aagagcttct gcggtataaa ctgctggtgc
    29521 gataccagag gcttcaatgg tgacaacctt ggtaatgccc aaatcagcat attgatcagc
    29581 aaatactcta ccgatttcct tcatcaagcg atagtcaacc tgatgtgtta aaaattgatc
    29641 caccttcaaa atcgtctcac ctaaaacagt accatcagct aagatacgct cctcaagtaa
    29701 cctcatcata tctccttttt atccaagtcc ctagagccct gccctgctgc acatagacac
    29761 aatgacctat ccaatcagca agcctaaaag ctttactggc tactagacat tcaggcgtcc
    29821 tgtagacacg ctgtgcttat tctcagtatc aatcaacttg cttatcctta tttagactag
    29881 gtctttagcc aagactttaa atagagtcac cattccaaat agaatttttc acgataacat
    29941 aattcacacg acgcaggctc tccaaatctc tgcctccggc atatgagatt gatgactgta
    30001 aatcctgctt catttcggtt aaagtatcag ctagatgacc cttggtcgga agcaaaatct
    30061 tcttaccctc aacattttta tgctcccctt tttggtattc agaggcagag ccataatatt
    30121 ccttgaagga ctgtccgtcg atttctacca tctttcctgg gctttcaata tggcctgcaa
    30181 agagtgaacc gatcatcacc attgttgccc caaatcgaat cgacttagca atatcaccat
    30241 gagtacggat accgccatca gcaataatgg gcttgcgagc agccttagca caccaacgca
    30301 cagcagccaa ttgccagccc cctgttccaa agcctgtctt cacctttgtg atacacacct
    30361 tgccaggccc aatcccgacc tttgttgcgt cagcaccagc attttcaagc tctcgaacag
    30421 cctctggcgt tccgacattt ccagctatga caaaggtctc aggcagttca gctttaatgt
    30481 gcttaatcat tttgatcaca ctatcagcat ggccatgagc aatgtcaatc gtgataaact
    30541 caggtgcgtc ttcctttaag gaagagacaa aatcgtattc ataatccttt acaccaaccg
    30601 aaatagaggc gatgagctgt tgctcatgca tgcgctggat aaagggcttg cgaccctcct
    30661 catcaaagcg gtgcataata tagaaataac catctcttgc caactgctct gcaattgttt
    30721 cgtcaataat ggtttgcatg ttggcgggaa taacaggtag cttaaaggta taattaccaa
    30781 gtcttacact cgtatctgct tctgaacgac tattgatgat acatttgtta ggaattaatt
    30841 gaatatcctc ataatcaaat acaggcatgt cattaaacat catttctctc ctttttcaac
    30901 attcagctac taatccagca aggacttccc tgatctgcag ctgacataag cttctatata
    30961 aaatgacctt cctatgacct caagcttgtc cgaggcatcg ctaggtaaaa tgttaccttt
    31021 ccttaattta ttttatcttt tcgtttatgt tttgtcaatt tttaaagctt tttttagatg
    31081 aatgttcgga ttttatttat tttaagattc caatccttag ctactaaatc aataaccaca
    31141 catcaaacaa gctgttattt ggcacacacc ttgcagagcc agacagacta aaaatcacat
    31201 aaataaagca tgccagtcca gaataagact agcatgcctg cttatttggt tcttgcaata
    31261 agaccggcct tgacaaggta gtcatgtgcc acaaggctag ctgctctgcc ctttacggac
    31321 acctcatagt tcattgcttg catctcctct tcagtaatct ttcctgataa ctgattgaga
    31381 atcgttttga gatgagggtg ctttcttagt aaggaagcct tcatcaatgg cgctccttga
    31441 taaggtggaa agagctgctt atcgtccttt aagactcgaa gctgatattt cacgatctca
    31501 gcatcagttg aataagcgtc tgtcagctga atgtttcctg actgaatggc ttggtaccta
    31561 agagctggct ccatcgttgc aactgataag tgtagaccat acttatcctg tatgccctta
    31621 tagccgtcct ctctatcctt aaattctagc gtaaaaccag cttttagctg tttttcatat
    31681 ttcttcacat ctgaaatact tttaatgtta aattcgtcag ctattttttc aggcatcgcc
    31741 actgcataag tattttgata ggcaaagggc tttaaaaacg tcaactgatc ctgctcagca
    31801 atcccctcct tagcagctaa ataaacctga ttaggatcat tagaaagctt gggctttttc
    31861 tttaataggc tagaggtgat ggttcctgta aattctggat aaatatcaat atctcctgat
    31921 ttaagcgcct cgtataaaaa gcttgtcttg ccaaaattag gtttcaattc aaccttaagc
    31981 ttggactggt cttcaatcag ctctttatag atattgatca aaatatccgg ctctactcct
    32041 agcttgccag caatcaccag agtatttgac tgattcacaa accgcttgac aaacatggga
    32101 gtataggaga ttaagagcag taataaggtc gcagcaaagc ttatcgcaat acgcctcagt
    32161 gaggccttct caaggtatct caaaagactg ttaaacacta tcgcaagcaa agccgatgac
    32221 acagcgccaa tcacaatcag ctgagcatta ttacgatcaa tccctaatag gataaaggtc
    32281 cctaagccgc cagctccaat caaagaagct agggtggctg ttccaatgat catcaccgct
    32341 gaggtccgaa cacctgacat aataactggc atagcaatag gaatttcaaa tattttcaat
    32401 cgttcccact tggtcattcc aaaggctgtt ccggcctcta caagacttgg atcaatagca
    32461 tttaagcctg taatcgtatt ttgtaaaata ggaaatatgg cataaataac caaagctgtt
    32521 acagctggag cagttccgat tcccattaga gggataaata gtcccaacaa ggctaaggaa
    32581 ggaatggttt gaaaaacgcc tgtcagctgc aagatgatat ttgaccagcg cttgctttta
    32641 ctcagcagag ccgcaagcgg aatacctatc agcaaggcaa ctaacaaaga aagaagagaa
    32701 atctgcaaat gctctcctaa agcccttgtc caatcgccaa aacgatccca aaaggtcatc
    32761 agtaaactag gcataatcac gacctccaaa tagactggct acaaagtcat tagcaggagc
    32821 agctatgatc gcatctggtc gatccagctg aacaatttgg ccctcattta agacagccac
    32881 acgatcccca agcttgatgg cctcatcaat atcatgagta acaaagacaa ttgtcatatc
    32941 aaactccttg tggaggctta gcatcaagtc ctgtaattgc ttgcgtgaaa tgggatccaa
    33001 ggctgaaaat ggctcgtcca ttaacagcac cttggggtga gaaatgatgg cacgaacaat
    33061 gccaatcctc tgctgctctc caccagataa atcacttgga tagcgattta gataatcctt
    33121 tgcaggcaat ccaaccttat ctaacaattc ctctgtttta gttctaatct ctttttctga
    33181 ccacttcttc atctttggaa tgatagcgat attttcagca actgtgagat ttggaaatag
    33241 agcaatttgc tgaaggacat agccaataga caagcgcatg tctcgcaaat ctagctcttt
    33301 ttgcggtctt ccatttaata gaatttcacc agagcttggt tcagtaaggc aattgatcat
    33361 ttttaagagt gttgttttgc cctacaatgt caagcaattg ttacataaaa ttagacgata
    33421 tttctatcgc ctaatttata tacaaaactt ttattttaac ttttttatac gttcactttc
    33481 tgttagaatc ctcatttgtt caatagcaat tgcatttaat ttttctatcc ttttagttgc
    33541 atccattccc tcatttataa aaacagcatt taagttctca agatttgata aacacactaa
    33601 ttgtgatata tcagcatagt ctctcatatt tccttttaac tccggataat tttcacgcca
    33661 ttcttttgct gtcattccaa acaaagctac atttaatata tctgcttcac ttgcatagat
    33721 atagtttatt ctttcctttg ataatttttc agggacaagt ttattcttaa ttgcatctgt
    33781 atgaattttg taatttatct tagctaaatt cctcttgata tcccaaccta attgtttttg
    33841 ttcttcttct tttaagcgct caaactcttt aataagatag agcttaaaat aaggtgatac
    33901 ccaagacgca aattcaaaag ctatgtcttt gtgtgcatat gttccaccat atcttcctgc
    33961 tttggcaaca attccgatag aattcgtctt attgacccat tgtttaaccg ataaaataaa
    34021 acgattaaaa cctgcttcat ttttaattcc ctcgaattcg gtggaattaa aattcgcatt
    34081 atacatttct tcccatattc ctaaaaattc aattgtattt ttattcctta gccatttttc
    34141 tattagtgcc acaccatttt caacatttct aaccatgtcg gtt
//
LOCUS       DARYSY010000021        33578 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYSY010000021 DARYSY010000000
VERSION     DARYSY010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33578
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(651..1667)
                     /gene="adhP"
                     /locus_tag="TVR04_000898"
     CDS             complement(651..1667)
                     /gene="adhP"
                     /locus_tag="TVR04_000898"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1269600.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(1870..2088)
                     /locus_tag="TVR04_000899"
                     /pseudo
     CDS             complement(1870..2088)
                     /locus_tag="TVR04_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989842.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
     gene            complement(2468..5110)
                     /gene="adhE"
                     /locus_tag="TVR04_000900"
                     /gene_synonym="adhC"
     CDS             complement(2468..5110)
                     /gene="adhE"
                     /locus_tag="TVR04_000900"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1269601.1"
                     /translation="MTEKNSTVETTTVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESREDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPDFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(5532..7313)
                     /locus_tag="TVR04_000901"
     CDS             complement(5532..7313)
                     /locus_tag="TVR04_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1269602.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQAIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMIGTCLTAPKV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIDALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(7310..7711)
                     /locus_tag="TVR04_000902"
     CDS             complement(7310..7711)
                     /locus_tag="TVR04_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269603.1"
                     /translation="MKAIIDKIQKWQITRVKLEIISVLVIIVCGLSVLTLTVSSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFHKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(7717..8175)
                     /locus_tag="TVR04_000903"
     CDS             complement(7717..8175)
                     /locus_tag="TVR04_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1269604.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(8416..9423)
                     /gene="ruvB"
                     /locus_tag="TVR04_000904"
     CDS             complement(8416..9423)
                     /gene="ruvB"
                     /locus_tag="TVR04_000904"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1269605.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGPPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(9457..9555)
                     /locus_tag="TVR04_000905"
     CDS             complement(9457..9555)
                     /locus_tag="TVR04_000905"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1269606.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            complement(9638..10552)
                     /locus_tag="TVR04_000906"
     CDS             complement(9638..10552)
                     /locus_tag="TVR04_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1269607.1"
                     /translation="MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSI
                     PSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELKYLILRTPTYMDDDKLKLREEQF
                     DEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
                     LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSL
                     SIKNNKPEILEKVIVLSQKIILKTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKA
                     CLFAQLTGDQYLEKKLREEWGKDIKRYQ"
     gene            complement(10851..12143)
                     /gene="purB"
                     /locus_tag="TVR04_000907"
     CDS             complement(10851..12143)
                     /gene="purB"
                     /locus_tag="TVR04_000907"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1269608.1"
                     /translation="MLTRYSRPEMANIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRENASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIAEKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFNRLGL"
     gene            complement(12740..12964)
                     /locus_tag="TVR04_000908"
     CDS             complement(12740..12964)
                     /locus_tag="TVR04_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1269609.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENSQAISEKMVELQHQYPDG
                     YLAVYDVQLDTDLSQLPHYPSIAIGKGEFE"
     gene            complement(12979..14052)
                     /gene="purK"
                     /locus_tag="TVR04_000909"
     CDS             complement(12979..14052)
                     /gene="purK"
                     /locus_tag="TVR04_000909"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019317169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1269610.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASLV
                     SEVIVAPYSDVEALRQLADRCDVLTYEFENVDAAALDAVVKEEQLPQGTDLLRLSQNR
                     IFEKDFLTNKVGVAVAPYRVVSSSLDLEQLDFSKNYVLKTATGGYDGHGQVVICTEAD
                     LEAANKLANSAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKAQAMAVKIAEQLNLSGTLCIEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAIKLHAPAVMLNVLGQHMEQAQAYITENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQPDEVEEF"
     gene            complement(14039..14527)
                     /gene="purE"
                     /locus_tag="TVR04_000910"
     CDS             complement(14039..14527)
                     /gene="purE"
                     /locus_tag="TVR04_000910"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1269611.1"
                     /translation="MKPIISIIMGSKSDWATMQKTAEILDQFGFAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            complement(14755..16017)
                     /gene="purD"
                     /locus_tag="TVR04_000911"
     CDS             complement(14755..16017)
                     /gene="purD"
                     /locus_tag="TVR04_000911"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1269612.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VNIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQAGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAVYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLTGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVKPVLKGMMAEGRPYRGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGSKAVK"
     gene            16375..17520
                     /locus_tag="TVR04_000912"
     CDS             16375..17520
                     /locus_tag="TVR04_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1269613.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNAESWGRIAKHQGYHV
                     DHIPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVVIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHMQMSHASQAGPASLAKSGTYYFSNQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNRRYIPIHKLPIQHSQGAIDKPKPVA
                     TTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDPAPLHETDHKGRIAG
                     NQILQVGDYFIVSGTYKVLKVDQPSRGIYVQMGSRGTWLTIDKAKKV"
     gene            complement(17912..19459)
                     /gene="purH"
                     /locus_tag="TVR04_000913"
     CDS             complement(17912..19459)
                     /gene="purH"
                     /locus_tag="TVR04_000913"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1269614.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASVRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAADQHGIAMIFT
                     GVRHFRH"
     gene            complement(19606..20163)
                     /gene="purN"
                     /locus_tag="TVR04_000914"
     CDS             complement(19606..20163)
                     /gene="purN"
                     /locus_tag="TVR04_000914"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1269615.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            complement(20160..21182)
                     /locus_tag="TVR04_000915"
     CDS             complement(20160..21182)
                     /locus_tag="TVR04_000915"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1269616.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKAAIKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IVEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVRACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            complement(21239..22696)
                     /locus_tag="TVR04_000916"
     CDS             complement(21239..22696)
                     /locus_tag="TVR04_000916"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1269617.1"
                     /translation="MIYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGAASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAISLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTEHQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTDTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEAAYLKSLEERVSFHIDQVTK"
     gene            complement(22793..26533)
                     /locus_tag="TVR04_000917"
     CDS             complement(22793..26533)
                     /locus_tag="TVR04_000917"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1269618.1"
                     /translation="MNKRIFVEKRADFQIKAQALLKELRHQLQLKTLVELRIVQVYDV
                     FHLDQELLLAAIKHVFSEQVTDQVLSEEAVQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELETLKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAKDFARYKSEQGLAMEVEDLLFIQDYFKSKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRRAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYTGLNGTEIAISESQERMAVVIYPKDLEAFMS
                     ACHKENIHAAVVATVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTASVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGIIETLALAAFGNQLGACVTLPELDRSLTAQLGGFVFTSKEEIAGAIRLG
                     QTTSDFTLIVNDVKLSGDRLLKAFEGSLEQVYPTVFQQAGDLQPVPVVTTALATQFKE
                     KIVQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDVSVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRAAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVKVGDIHAVAVS
                     HGEGKLVVTERELAELCENGQIFSQYVDLDGKPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVDID"
     gene            complement(26698..27408)
                     /locus_tag="TVR04_000918"
     CDS             complement(26698..27408)
                     /locus_tag="TVR04_000918"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1269619.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLIVYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKKVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            complement(27555..27803)
                     /locus_tag="TVR04_000919"
     CDS             complement(27555..27803)
                     /locus_tag="TVR04_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1269620.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            complement(27796..28803)
                     /gene="plsX"
                     /locus_tag="TVR04_000920"
     CDS             complement(27796..28803)
                     /gene="plsX"
                     /locus_tag="TVR04_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1269621.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYKLLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKLGALLLKGSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDAN
                     D"
     gene            complement(28919..29689)
                     /gene="recO"
                     /locus_tag="TVR04_000921"
     CDS             complement(28919..29689)
                     /gene="recO"
                     /locus_tag="TVR04_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1269622.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEIQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            complement(30049..31011)
                     /locus_tag="TVR04_000922"
     CDS             complement(30049..31011)
                     /locus_tag="TVR04_000922"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1269623.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            complement(31116..32294)
                     /locus_tag="TVR04_000923"
     CDS             complement(31116..32294)
                     /locus_tag="TVR04_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1269624.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSAPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGGTP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            complement(32390..32893)
                     /gene="mreD"
                     /locus_tag="TVR04_000924"
     CDS             complement(32390..32893)
                     /gene="mreD"
                     /locus_tag="TVR04_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1269625.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            complement(32896..>33578)
                     /locus_tag="TVR04_000925"
     CDS             complement(32896..>33578)
                     /locus_tag="TVR04_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1269626.1"
                     /translation="IDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQL
                     QVDKLKSENRELKELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVT
                     SELGLIGRVTAVSQSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVAS
                     EFNSNESISLDAKVYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLD
                     YVLVVGKE"
BASE COUNT        10032 a         7904 c         6010 g         9632 t
ORIGIN      
        1 cttattcggg acacaacatt tttcatctat attttaaatc atactacctt gttactaaaa
       61 acgtagataa taatttagct tataacccat gtttttagca atatgttatg tcattattct
      121 tttttcctac agtgcttcct aaaatttgtg aagacgaatt gtcaaattaa gtgcaacgct
      181 tttccataaa agagtttata aggtagtttc cagttaggac atcttctaga acgatcattt
      241 catttatctt cccactctta tatgatagag ctctcaatat cagtcaagtc agttccttta
      301 ggaaactact ctttgattaa cccattggta ttttcatttg tcctacgtta tcaaggggtg
      361 tgaggagcag agaaataaac ttctagattg agttcctgtg ttaatctcta atattgttca
      421 aacccaatat ctctatcaga ggttacaata tgtccaactt tctctggtac tgtctttcaa
      481 ggggcaatca tggtattaat aactagctgg ctcttttaca tctttagata ccaagctttt
      541 tttaccagtt agtttcacca aaaaagccct tagaaaatta attctaagga ctttattcat
      601 catttgggac aatcagcttg tctggctgct gactttttct gaaatcagcc ttaaagcgtg
      661 aaatccaata cctttcttcc ttgaatgaga ccacgttcca tttcgtcaaa gacttctgga
      721 gcagtctcaa ctggaacctt ttctacaact ggcacaacca gaccttctgc accaaaggca
      781 aaggcttctt ccaagtcttt acgagttccc acaagtgatc cgactacctt gattccgtct
      841 aggacagtct ttacgataga taattccatg tattctgatg gaagtcctac agcaacaaca
      901 gttcctcctg cacgcacact atcaatagct tggttaaagg ctactttaga aacagcggtt
      961 accacaacgc catgagcacc acctgttttt tcttggatat agccggcaac atcttcgatt
     1021 tctttaccat tgacaacgat atctgctcca acctccttgg ccagctctag cttatcattg
     1081 ttaatgtcca ctgctacgac atgagcattg aaaacctttt tagcatactg aacagctagg
     1141 ttaccaagtc caccggcacc aaagataaca atccattgtc ctggagcggc acctgcttct
     1201 ttgatagcct tataggttgt aacgcctgca caggtaattg atgatgcttg agctgggtca
     1261 agaccatctg gcactttcac agcatagtca gctgtaacaa ctgcatactc actcatccca
     1321 ccatcaactg aatagccagc atttttgact gaacggcata gagtctcgcg acctgttgta
     1381 caatattcac aatgaccgca gccttcaaag aaccaagcaa ttgatacacg atcaccaacc
     1441 tttaaggagg taacgccttc acctagcttt tcgacaatac cgataccttc atgaccgagg
     1501 atacgccccg gaacctgacc aaaatcacca tgcgcaacat gcaagtcagt atgacatacg
     1561 ccacaatatt ctactttaac aagagcttct ccatgaccga ttgatggtac atcatgctct
     1621 acaacctcta caccactgct ggtttggtta acaactacag ccttcatagg atgcctccaa
     1681 tttctaagtc tcggtttatc tatttttgca accgtttaca atttgtattg tatacttttt
     1741 cacaaggttt gtcaaccaat tttttgaaag ttttctgaaa ataaacttaa ccagttaagt
     1801 tggctaaata acagcatctg gaccattcca aatgctgtta tcatttttat ctatttatac
     1861 cttattcctt taggctgtaa tgtcattttc aataatcact ttaagggcgt tattactgcc
     1921 agcattttta aagacctcat aggctttttc aacctctgac agcttaaagt gatgtgttac
     1981 catcttggtt gcatcaatct tacctgattt tagaacattt aatagcattt ctgttgtatt
     2041 agcgtttact aggccagttg acattgtaat gtttttgatc cataggtcct tgtttcgctt
     2101 tttatttgat atatcaaggt ttttagcgtt attactatca ttaaaaaagc aattaatcct
     2161 cgttttatta gaaaatggac ctcgtcagat agacttaaca ttttattctt ttcagctaat
     2221 tgctaagtgc agctaagtcg taactatcag ccactttatg aatatggcaa atgaagcttc
     2281 cccctctgat ggaatgctct gtaaaaccat tgtcttaaaa gctttatatg atatctgaga
     2341 aactacccct gagttaagct atctcaacac aaggtactgc tggtcttttc atctaacaca
     2401 atcttcttca tagctagata aaaaaataga agccaagcag ctcctatttt tttattaatg
     2461 cttattttta tttccgacgt cctggacgct ctgcgtaacc ataataagca tcattcatga
     2521 tttcttccat gtgctcaacc attggcaagc gtgggttagc aggtgagcat tgatcctcgt
     2581 aggcaagata agcaagctca cgagtgtgtg ccttccattc ttcctcatca atgccttgat
     2641 ctctgaaatt catcttaatg cctaagcggc agccaagatc ataaacagcc ttagcatagg
     2701 attcaacccc ttcttctgga gtagatgctg gaagccctag caatttagcg atgtcttgat
     2761 atttttcatc agcgcgatag taattgtact taggccatgt tgctgtttta gcaggacgtg
     2821 ttccattgta acgaataacg tatggaagca agatagcatt ggtacgtcca tgaacagtat
     2881 ggaattgtgc accaatctta tgagccattg agtgagaaat acctaggaag gcattagcaa
     2941 aggccatacc tgccattgtt gaggcattat gcattttttc acgtgactca aagtcagctt
     3001 ccttaacaga tttttcaagg ttttcaaaga caatcttaat ggcttgaagg gccaaaccgt
     3061 ctgtaaagtc attagccatt tgtgatacgt aagcctcggt tgcgtgggtc aatacgtcca
     3121 tacctgtatc agctgcaatg aagtctggta ctgtaagcac caacgctggg tcaacaatgg
     3181 ctacagtcgg tgtcaatgag tagtcagcaa ttgggtactt acgattgtta gccttatctg
     3241 agataacagc aaatggtgtc acctctgatc ctgtacctga ggttgttgga atagccacaa
     3301 attttgtttt tttaccaagc tcagggaact tgaaggcacg cttacgaata tccatgaatt
     3361 tttgaacaag atcatggaag tcaacctctg gttgctcgta gaataaccac atcaccttgg
     3421 cagcgtccat tggagaaccc ccaccaagag cgataatcgt atctggcttg aaggtacgca
     3481 tcaactcagt acctttcata accgttgtga tatcaggatc tggctcaaca tctgcaaaaa
     3541 tttgataaac aaccttatta cgacgaaggt caagctgctc gatgatacga tctaagaagc
     3601 caagctcaac catcgcgtgg tcagtaacaa tcatcacacg ctcaacgtca cgacattttt
     3661 gaaggtattg aattgaatca cgctcgaagt atgtttttga aggaacttta aaccattgca
     3721 tattatttct acgtcttcct acttttttga tattcaagag atttacagca ctaacattat
     3781 caccaactga gttacgtcca taagaaccac agcccaatgt taatgacggt aggaaggcat
     3841 tgtaaacatc accgatacca ccaaaggtag aaggtgagtt ccaaatcaca cgaatagcac
     3901 gaatccttgt accaaattcc ttggctaaat ctgcatcagc agtatggata gctgctgagt
     3961 gaccaagtcc attaaactca accatctgac gagccttttc aacaccgtcc tcacgagatt
     4021 ctgccttcaa aacagcgata actggtgata gcttttcacg tgttaatggc tcattttcag
     4081 aaacttcctt acattctgct gcaaggatat tcgttccctc tggcactgta aagccagcct
     4141 gctcagcaat ccaagttgct ggcttaccaa caatattagg gttcagctta gcacctgcac
     4201 agtttttact attagccttg gcaccaaaac agaattcctc taacagagcc ttttcctttt
     4261 tgttgacaaa gtaagtgtgg taagacttaa attcactaac aaactcgtca taaatttcct
     4321 tgtcgataat aacagcctgc tcagaagcac aaaccatacc attgtcaaat gatttagaca
     4381 tgacaatatc gtgtgctgcc tgacgaatgt tagcggattt ttcaacatag gcaggcacgt
     4441 taccagcacc aaccccaaga gctggcttac cacatgagta ggctgcctta accatagcat
     4501 taccaccagt tgcaaggatt gttgcaatac catcatgatt catcagagcg ttagttgctt
     4561 ctagtgatgg ggtttcaatc cattgaacac agtcctcagg agctcctgct gcaatcgctg
     4621 catcacgaac aatgcgtgct gcatgagctg atgattcttg agctgatggg tggaaggcaa
     4681 aaataatagg gttacgtgtt tttaaggaga ttaaagattt aaaaatagct gttgacgttg
     4741 ggttagttgt tggggtaatc ccacaaataa cacctactgg ctcagcaatt aaggtcaaac
     4801 ctgttacatc gtcttcttca atgataccta ctgttttttg gtgacgcatg ttattaacaa
     4861 cgtgctcaca tgcgaaaagg tttttggtag ccttatcttc aaaaactccg cgaccagttt
     4921 cttcataggc atgcttagct aactcaccat gtgcgtccaa agcagcaaca gaggccttcg
     4981 ctacaatgta gtcaacctgt tcttgagtta attggcgcat tttatcaagc gctactaaac
     5041 ctttttgaac aagagcgtca attgttgcgg caacagttgt tgtttcaaca gtactatttt
     5101 tttcagtcat ttgagactcc tttaccttgt taaaagtttc acaattttgt ttacaaaaat
     5161 attatatcat tttttggcat tttgtaaatc atttcacaat aaaattgtga tgtttttttc
     5221 aatcaatttc tgaaaccctt tgataacaag aggtttggct tggtggattt tttctgaaat
     5281 aatggctgac gcattcactt tgttctgaaa tcgctttctt tttttagatc aggctaaatt
     5341 atttaatgat ccgcttttag agccacctca ccgtcagcaa taacagccaa taatgacact
     5401 gtctaacagg tggagcttta tctcgcacta aagggcgcaa gacgatctaa aaatcacatc
     5461 atgaaaaggc ttgatctgtt tgtaagacca agccttcgtt attgattctt aacaaattgt
     5521 tgttagcatc actatttagc atcttttttt gctgctcgct caacagccgc ctgaatcgtt
     5581 gagacatata agtcagcacc ttttaatttg gcgtcgttat tgtagtggac cccatcacta
     5641 ccataccaga tattgggatt ttcgactgcc gccttgtacc agtcagcaac tgttacatag
     5701 ctatattttt tagctagctg caacaaatgc tctctagcct ctgctacctg tgctgcattc
     5761 ttagcatcat agggcgacac aatcaccaag cgatgcccct ttggcagagc atcaataaag
     5821 ccttgaatat cctgcgcata attataaagg gaattaacac caacagctaa aaccgttgtt
     5881 tttgataagc tcttggattg gatatgattt tcaaaaagct caaaggcttc actgaaattg
     5941 cggctaacag cggcgtctag ctgagcagtc ggcattaatt ttgaaaaagc gtcactagac
     6001 ctcaaggcaa ctgagtcacc aataatgcta acatcactaa gagcatgcgc atctcctgct
     6061 gccaaagtat gtgtcttatt gagattactt tgagattgct gcaaggaatc tactaaaagc
     6121 tgtgtctcaa aattgccgac ctttggtgct gtcaaacagg taccaatcat caacaaaaag
     6181 agtcctaaag caagccctga taaccatttc ttatagggat tacaatcaat tgctaaacca
     6241 aaaagctgtg gtgtcttacc ttgaatcaaa ggctcaataa tgtaataaga aagcgttgaa
     6301 aacactactg aaaagaaaac cgttaagatc actgccagcc agttagacat cagctgtgta
     6361 aaaataatgt aaaatggcca atggaataaa taaatcccat agctaatatc cgcaagatag
     6421 gtcacaagca gtggttcctg ccaggttggt gtttgatcgc tcaaaacacg cgcagcataa
     6481 atcattaccg aagcaaaaag actggctaag acaaaaccga aaagataggt aaagatatgg
     6541 ttaaaatcta acacaagcgt tagaaacagc aacagagcaa aagcgccagc catcactcca
     6601 ataacatgta gccttggcca cagcttaaca ttcttttgaa agcgaacagt cgtgtcctta
     6661 attcccgtca tggttgcaaa catcgctcct aaaaagaaag gaaagctgtg tgaaagcgtt
     6721 gaaaagtaaa cagaagaaaa atctgataca aagaaggctc tgataaacat gctgaagtag
     6781 ctaagtgtaa atactgctga ggaaattaaa aacagaatgc ctctaaattt cttctgactg
     6841 tagccttttt tagctaataa ccaaaccaac agcccccaaa gcaaataaaa atgcacttca
     6901 atagccaagc tccaggtatg cacaaacaaa tgcggaatga attgactttc atagctactg
     6961 cctgtcagca gctcataact atttgttgta aaccctaggg cagctgctat ttgctgacca
     7021 ataccagcaa tgaagtcact tttgactaaa aaagtgaagg gaattgttaa gagaattaac
     7081 aagacaagcg gcggtacaat acgataaaaa cgccttctaa aaaaagcaac cacatcaatg
     7141 gcctgttttg agacatattc atcaatcaac aaggctgtaa tcagatagcc cgaaaaagta
     7201 aagaagatgt caacgccaac aaagcctcct gaaaaagtat gcttaaaaaa gtgatagagc
     7261 aacaccagca aaagacctgt taccctaata aacgaaaacc attttatcct catttttgaa
     7321 atatcccctg cttaaaggtt cctttgtaaa cctttgaatc cttcgccttc aaagtgccct
     7381 tgccatcagc ctgacctttt ttaaattgtc cgctgtaaga ccaccctgta ctagccgtaa
     7441 atgttccttc tccgtcaaag actcccttat gaaaatctcc aacataagta tccccatttg
     7501 gataaaccag tttccccttg ccattcattc tgtgattaag gacatagccg gtgtacttga
     7561 tttgcccatt gtcataggtt aagcttgctt ttgacgatac agtcaaggtt aaaaccgaca
     7621 atccacagac aataatcaca agaactgaga taatctctag ctttacccga gtgatctgcc
     7681 atttttgaat cttatctatt attgctttca ttactattac tcatctattt ctacatgtga
     7741 ttcatgttca gcgctgattt gactcaacca atgctgacag cccgctttaa ccaagcgata
     7801 ggtttcttca aaatctcctg tataccaagg atccggaacg cctccctcaa taaaaagatg
     7861 gatcttggaa tcccactgat gcttggacat ttgcttcaaa tccctgatat tatgactatc
     7921 cattccgata atatagtcaa aggcttcaaa gtcaaagctg gtgatttgct gagaggtttt
     7981 cttggtatca tagctaatct gatattgctg taatagcgat tgtgtcccat gatgaattgg
     8041 attgccatgc tcccagccag aggtcgcacg actctccacc tgtagctcat caggactggc
     8101 catacttttc atgacaaatt cggccatagg actacgacaa atatttccaa gacaaacaaa
     8161 gcatactttt ttcatgaaaa actcctttta cctattatag caaaattata gggccaaaag
     8221 gagaaatcgc tcttataatt ttcgttcaat tgatctaaaa atgtttttta atgctttgtc
     8281 tagtgaaagc acctctgctt ccctgaccaa tcacccctca cctcacatcg ttttactttt
     8341 ttactcagta agctattgac aatacaaaag acttgacacc ggtaaaaaca aaggaatcaa
     8401 gtcttacata gctatttatg tcttaatggt tttttcatag ggatagccta agtgctgata
     8461 ggctttttcg gtgacaactc ggcctgttct ggtacgcatg ataaaaccct tttgaattaa
     8521 ataaggctcg tacatgtctt ctactgtatc tcgctcctct gctatattga cagatagagt
     8581 cccaagacca accggccctc cttggtacac ctcaatcatg gtacgaagaa tcttttggtc
     8641 cacataatct aaaccttctt gatccacatc taacatcgtt agagccttat ctgtgatttg
     8701 agtcgtaatc attccatcac ccataatttg agcataatca cgcacccttt ttaacagccg
     8761 attagcaata cgaggggttc cacgactcct gcgtgccagt tcataagcgg cctcatgctt
     8821 gattgtcatg tcaaaaatat cagctgtacg ctccacaatc tctgttaaat cagctgtctg
     8881 ataatattcc atatgcccag taatcccaaa acgagccctc aaaggatttg acagcatgcc
     8941 tgcacgagtc gttgctccaa ttaatgtaaa gggaggcagc tccaaatgca cactccggct
     9001 agtgtctcca gcgccaatca tgatatcaat gtaaaaatcc tccatggcac tgtacaagat
     9061 ttcctcaaca gccatcggca tacgatgaat ttcatcaata aagaggacat ctcctggctc
     9121 taaatcattc aaaattgcca ccaaatcacc agctttttca atggctgggc cagaggtctg
     9181 cttgagatga actcccaatt cattggcaat gacaaaggcc atcgttgttt tacccaagcc
     9241 tgggggacca aataacagga catgatccaa ggattcctca cgcctcttgg ctgcctcaat
     9301 aaaaatcatc agctggtctt taaccctatc ctgaccaata tactcacgta aatactgtgg
     9361 acgtagtgtc ctctcaacag atccttcatc gcctatcaga tcattatcta aaattcttgt
     9421 catagagcta ttatagcata aatagatgat ttagctttaa ccaacacgcc accagtcaat
     9481 atcactaagt aattgggcag aatgaagtag aaataaagca gctaaaaaca gatagtattg
     9541 gtatttttta aacatataaa tggaactcct ttaatcaatt atttgttata taaagattat
     9601 atattattcc atttttgata aaaatgacat ttttgtccta ttgatatcgt tttatatctt
     9661 taccccattc ttctctcaat ttcttttcca aatactgatc tcctgttaat tgagcaaaca
     9721 ggcatgcctt atcatagcat tttttggcca tttctatgtc ttttttcttc attagagcat
     9781 atttccactc tatcaaattt aagataggca ttctattaaa atcctgagtc ttgaggataa
     9841 ttttttgact aagtacaata accttctcaa gaatctccgg cttattgttt ttgatgctca
     9901 acgaggaaat tcctatagct attttattga caataaataa ttcctctaat tcaaaatgtt
     9961 caaactgatt taacaaaatg tctaacaaag aatcatagaa tcctttatct gaatactctc
    10021 cattcattcc tgcaatgtcg aggtacgcta aatacagctc aataagaatg agatcattct
    10081 ctctaaattg agtcttactt tttgtttgtt caaagtattc ctgtaataac ccaactccaa
    10141 aattgatatt ctcggttaat aacgtatcca ttatggactg caagcagtcc accacaagct
    10201 tttcttcctc tggcaactgg tcataataat cttcaaaaat ttcgtcaaat tgctcttctc
    10261 gcagctttaa tttgtcatca tccatatagg tcggcgttct taaaatcaaa tatttaagtt
    10321 ctttataacg cttaggcagc tccaaatcct ctccgtctgt caaaaagccg acactaacgt
    10381 ccagagcctt agcaatataa accacctttg ataggctggg aatcgattgg cccaattcta
    10441 ttcgtgctaa ttgacgaatg gataattctg actcatctcc acataaatcc tctctggtaa
    10501 tcttcttctg ataccgcagg tctctcacct tttcaccaaa attgtctaac atgtttccct
    10561 cttcaagaca ctatttcttt cattatatca cataatttaa ttaatcatta attttttgac
    10621 tccattttgt aataacattt ctgtattttt agaaaaaaag aaggcctatt gccttctcag
    10681 attgaaaaaa tgtctatttt aaagcatttc cctaagcaat acagctagta acagcctctc
    10741 ttagaatact attcttcatt ttgaggatta gctccgagtg attaattttc aaggcttttt
    10801 taaacaaatc taggctaggc tacactctaa aaagacgcac tatcttattc ctataatcct
    10861 aatcgattga aaatagcatc gacacgcttg gtgtaatagg ctggattgaa gagctcatca
    10921 agctcatctt gccttaattt tgcagtgatg ttttcgtctg cctcaaggag tggcttgaag
    10981 tccacttggt tgtcccatga gtaggctgtt tttggttgta ccaagtcgta agcttcctca
    11041 cgcgtcatgc ctttttcaat gagtttcaac atcacacgtt ggctgtaaat caagccaaag
    11101 gtagagttca tgttacgaat catgttttct gggaagacgg tcaagttctt gacgatattg
    11161 ccaaaacggt tgagcatgta gttgataaga atcgttgtgt ctggtgtgat gatacgctcc
    11221 gcagatgagt gcgaaatatc acgctcgtgc caaagcgcca cgttctcata ggctgtcacc
    11281 atgtgcccgc gaatgacacg cgcaagaccc gtcatgtttt cagagccgat cgggttacgc
    11341 ttgtgaggca tggcagagct tcctttttga cctttggcaa agaattcttc tacctcacgt
    11401 tgctcagatt tttgcaggcc acgaatttca gttgccatac gttcaattga tgtcgcgata
    11461 ctagcaagca ctgcaaagta ctcggcatga aggtcacgtg gcaagacctg agttgagatt
    11521 tcctgcgggc gaatgcccag cttgccacaa acatactcct caacaaatgg gggaatatta
    11581 gcaaaatttc caacagcacc tgagatttta ccagcctcaa cgccagcagc cgcatgctca
    11641 aaacgctctt gattgcgctt catttcactg taccaggtcg ccaatttgag accgaaggtc
    11701 gttggctccg catgcactcc gtgggtacga cccatcatga tagtcatttt gtgttcacgt
    11761 gccttttcag ctataatgtt cgtaaaattt tcaagatcac gacggataat gtcgttggcc
    11821 tgcttgtaga gatagccgta agccgtgtct accacgtcag tcgatgtcaa gccatagtga
    11881 acccatttgc gctcctcacc gagcgtttca gacaccgcac gcgtaaaggc caccacatcg
    11941 tgacgggtct cttcttcaat ctccaaaata cgattgatgt caaagctcgc attctcacga
    12001 atcttcgcca catcttcctt gggaatctca cccaactcag cccatgcctc atcagcgagg
    12061 atttccacct ccaaccaagc acggtacttg ttctcttcac tccaaatatt cgccatctca
    12121 gggcgtgaat aacgtgttag cataattaag ataccaagag cggccagaaa gcacctgaat
    12181 tttagaaaac taaagacgga catttatgtc cgaggaaatt tatctaaatt ccgagctttc
    12241 cgctcgggtt cagtttggaa attctagcgc tcatttcctt tctacatagt taatagtaat
    12301 gcttttaaag tctattcgca ataatttcta tattgtgatt aaaagttagg gcatcaatag
    12361 ttgactatac caatattgta aacctctttg catgtatata aaagatctgc tttgtcatga
    12421 tgcatctagt aagttcatta tgtacaaacc tatctatatg ttatcaatct agacgaaata
    12481 ctcttagaag ttttatatgg aaatatctca ccacgataat ttttgagttc tacacctcca
    12541 gaagctacaa tttcaacatt tctcttatga ttgctcgaga tcagtatcta gaattatcca
    12601 ttaagtcatt taccaacttc tgaaatctga ttacgattct caattctcac aacatgctca
    12661 acatcatgac caatcttttg aaaggcatag ccataaattg tcccaataac actcaatccg
    12721 aaatactaat cttccttaac tactcaaact cccctttgcc tatcgctatt gacggatagt
    12781 ggggcaattg cgataggtct gtatccagtt gtacatcata aacagctaga taaccatctg
    12841 gatattgatg ttgtagttct accatttttt cagaaatagc ttgagaattt tccgaagcaa
    12901 agacaacttc aacaacgcct gtttcaccat tttcaataaa agcgtgaaca atgattttta
    12961 tcataggatt aattcctcct aaaattcttc aacctcatct ggttgactgt taaacaccgt
    13021 cacgtgtccc attttgcggt tgtgcttggc ttctatttta ccatagaggt ggaggtgggc
    13081 gctagggttt tctgtgatat aggcttgggc ttgttccatg tgttggccga ggacgttgag
    13141 catgacagct ggggcatgga gtttgatagc tggtaatggc tgtcctaaaa cacccaagat
    13201 atgagtgtca aattgtgaaa aatcacaggc ttcaatggag taatgtcctg agttatgggg
    13261 acgaggagcg atttcattga ccagaatctc atcgcctgcc acaaacattt ctatacagag
    13321 ggtgccagat aggttaagct gctctgctat tttcaccgcc atagcctgcg ctttagcgct
    13381 aactgcttct gaaatgcgag ctgggacaat ggtttttgac aggatattgt tccgatggat
    13441 attttcctga acaggaaaga cagtgacatc tgtgccattg ccagatacaa taacggaaat
    13501 ctctcggtca aagctgacaa attcttccaa gacgcactca gcagagttgg ctaatttgtt
    13561 tgcagcttca aggtctgctt ctgtgcaaat cacgacttgt ccatgtccat cgtagccgcc
    13621 tgttgctgtt tttaagacat agttttttga gaaatccagc tgctccaagt caaggctgga
    13681 ggacaccaca cgataaggag ctactgctac accaacttta ttagttaaaa aatccttttc
    13741 aaaaatgcgg ttttgagata ggcgaagcag gtccgttcct tgcgggagct gctcctcctt
    13801 taccacagca tcaagcgcag ctgcgtccac attttcaaat tcataggtca agacatcaca
    13861 acggtctgct agttgacgaa gagcctccac atcactgtaa ggcgccacga taacctcact
    13921 cacgagcgag gctgggcaat ccgctgctgg atccagtgta atgaccttat gccccatata
    13981 aatggcagaa atcgccatca tctgtcccag ctgaccacct ccgataattc caattgtttt
    14041 agttgagttc atgggttgac tcctctgcga tccgtccttg ctctttgtgg aaatggctga
    14101 gctgctctgc gattgtttca tcctcaattg aaaggatccg aagagcagtc agtgctgcat
    14161 tggttgctcc tgcttctcca atggccatag ttgccacagg cacaccacct ggcatctgca
    14221 caattgaata cagcgaatca agaccactaa gagcacgcga tttgacaggt acgccgataa
    14281 caggaagtgt cgtctttgca gcaaccattc cagggagatg ggctgctcct ccagcaccag
    14341 cgatgatgat tttaatacca cgttcgcgtg ctttctcagc gtatgtgaac atgagatccg
    14401 gcgtgcggtg ggcagagacc actttttttt cgtaggcaaa gccaaactgg tcgaggattt
    14461 cggcggtttt ttgcatggtg gcccagtcag atttggagcc catgatgata gagataattg
    14521 gtttcatatt ttctccttaa aggtttttga tacttttctt aagtggctgg gtcgtcagca
    14581 gtcaccatag gtgtctcatg actaacttga aagcccaagg tctttcaaat tcccctgagt
    14641 gaccctgtca ctctttgcgc cacgtcgaaa agtatcgtgt taggctcgct ttcgctcgcc
    14701 tattataaat cattgttatc atagcgacct tcggtcgctt gatctagcgc taatttattt
    14761 tactgctttg cttccgatat cgtttcggta gaataatcct tcggtatttt gctgagcaag
    14821 ttcggtatag attttttctt gcgcagctgg gacggtaact gctgtggtga ccagcatata
    14881 gacacgtcca ccatttgaca gcagtgcttt gccattttcc gcaagcttaa cccctgcgta
    14941 gtaggtaatg atgtcgccag tggtctttgc tggcagaagc acacctttct tgtaagcaag
    15001 cggataaccg tttgaagcaa ggacaacgcc gagcgtcact ccctcgtctg accatgtgat
    15061 attagctgtg ttgccctcta atatatcggt aatgttctgt gcaaaatcag aggtcaggcg
    15121 aggaaggata acctgagtct caggatcacc aaagcgagca ttgaattcaa tcacttttgg
    15181 tccatcttct gtcaaaatca agccacaata gagaatccct cggtagggac gcccctctgc
    15241 catcatgccc ttgaggactg gcttcacgat agtctcaaca gctgtatcca ccacactttg
    15301 agggagatga ggaactggcg cataggctcc cataccacct gtatttggcc ccttgtcacc
    15361 atcaagagcc cgtttatggt cctgcgctgt cggcatgagg taaaactgat caccattcac
    15421 aaaggcaaag agagagaatt cttcaccagt taaaaactcc tcaatcacca cgcgtgcacc
    15481 tgaatcacca aatttattat ccaagagcat gtcacgcgcc gcctcaactg cctgctctac
    15541 agtctctgct acgacaacac cctttcctag cgccaaacca tctgccttga ctacgattgg
    15601 cgcgcccttt tcttcgatgt aggccttggc ttttgcaaaa tcagaaaatg tgccatagac
    15661 tgctgttgga ataccgtatt tgaccatgat ttgcttagca aagtcctttg accactccag
    15721 ctccgctgct aaacgagagg gcccaaaggc tttcaagcca gcctggttaa actcatcaac
    15781 aataccagcc gctaatgcgt catctggtcc cacaaaggtc caggctatat gattggtctt
    15841 tgcaaaagca atcaaagcag aatgttcgga aatatcaata tttacccgct ctatgccatc
    15901 aagggtcatg ccgtcattgc caggtgccac aaaaacctgt tcaacgcctt ttgactctaa
    15961 caatttctta gcaatcgcat gttcacgacc acctgaaccg ataactaaaa gcttcatcac
    16021 acacctcata atacgaattt tataaacata ttttagcata attgttcgtt tatataaata
    16081 actaatcacc aaagaaagcc caaaacataa aaaaaatgat acctttttta aaaataaggt
    16141 ttatagaata aaccaccaaa tctcatataa ccacaactta cctcttcaga tgaggtgtta
    16201 gcgtctacta taaactgctt ttgctacagg gatcaggcgg cttacctatt gcctcttgga
    16261 agctagtgag tactaacagt gatttaggag ctgaaatatt tttccttacg attttttaaa
    16321 tcaaggacat ttttgtcctc tttcttgcga atagtaagtt acaggaggta attaatgaaa
    16381 aaagtctatc aattgttagc ttcaggagca atccttttag gtggtaatgg tgcaatatcc
    16441 tctgccacaa caacgatttc acaaggtcag tcaggtatcg tacacgctgc tgttttaggg
    16501 gataactatc caagtaagtg gaaacagggc ttcggagctg atccttggaa catgtactta
    16561 cgtcagtgca cttcttttgt agcattccga ctgcattcct caaatggatt cagcctgcct
    16621 agaggctatg gtaatgctga aagctgggga cgtatagcta aacaccaagg ctatcatgtt
    16681 gatcatatac ctagagttgg cgctgttgct tggtgggata agggctttaa ccaatcacat
    16741 gctctatatg gacacgtcgc ctgggtagca gaggtcaatg gtgacactgt tgttattgag
    16801 gaatacaatt ataatgccgg acaggggcct gaaaagtacc ataaacgaca gattcataag
    16861 catcaggtaa gtggttatat tcacttcaag gatctggatc acaactctac cagccacatg
    16921 cagatgtcgc atgcctctca agcaggacca gctagtttag ccaaaagtgg aacctattat
    16981 ttttcaaacc aaagtcctat aaaggctgaa gctacattag caagtcctga tttagcttac
    17041 tatcatactg gacagctggt gcactatgac caaacccttg tcgctgatgg ctatgaatgg
    17101 ctcagctata tcggtcattc aggaaatcgt cgctacattc cgattcacaa attgcctatt
    17161 caacatagtc aaggcgctat agataaacca aagcctgtgg cgaccactcc tatcaaggtt
    17221 ggagatactg tagcctttcc tggtgttttc cgagtagacc aggttgctca gaacatgatt
    17281 gcaagtagtg aattagccgg tggagagcca acctcattaa actggataga cccagctcca
    17341 ctccacgaaa cagatcacaa aggacgtatt gctggaaatc agattttgca ggtgggtgat
    17401 tattttatcg tttcaggaac ctataaggtt ttaaaggttg atcagcctag caggggcatt
    17461 tacgtgcaaa tgggttcacg tggaacatgg ttaacaatag acaaagcgaa gaaggtctaa
    17521 aacctttagg ctaacgaaaa agccttttat gataatactt ttctaaaata atatagacag
    17581 tactgtctcc attgaaatct cctctttagg tgatgcatct agagctcaaa acactcaaat
    17641 actgattgac agcggatatg gttactgtta ccacaataaa aagtaaggct ttaggttggc
    17701 atcgtttgtt aagagatttt tgtattatcc atagtaaaaa gaggctgaaa gaacaggctg
    17761 accccaaata aaacaagcga acaagactag ttttctgaga ttatgaaaac tagtcttgtt
    17821 cgctttttaa tgagttaaac taagtaataa agtatattag cccaaaattg ctaaagtgca
    17881 actctttttg ctctggcctc tttttactct attaatgtct aaaatgcctc acacctgtga
    17941 aaatcatggc tatgccatgc tgatcagcag ctgcaataga ttctgaatca cgaatagagc
    18001 ctccaggctg gataatagcc ttgataccag cggcagcaat ttcttcaatg ctgtctgcaa
    18061 atgggaagaa agcatcgcta gcaagaactg ctccctcaag ctgccccgtt gcttgcgcaa
    18121 tagcaatacg aacagaggct attcggtttg tttgccctgg accaacgccc aaagtcatat
    18181 gatcattagc aatgacaatc gcattagact tgacatattt gatagttttc caagcaaatg
    18241 ctagagcagc catttcctgt tcatttggct gacgctttgt caccactatc caatctgccg
    18301 gagactctgt gacaacatct tgattttgca ctagtagacc accaagaact cctgtatatt
    18361 ctgcttctat ttcactagcc tcctgagcag caaatggcaa ttcaagaatt cgcaagtgct
    18421 tctttttatg ggtgagaaca gctagcgctt ctttggaata gcctggtgca atgatcaatt
    18481 ccagaaaaat agcatgaagc ttctccgctg tcgctagatc cacctcacga tttaggacaa
    18541 caataccacc aaagatagac accggatcag ctgcataagc aaaatcccaa gctgtctcaa
    18601 tatcatctgc ctgaccaata ccacatggat tcatatgctt gagtgctaca acggttggac
    18661 gctccttaaa atcacgaata atacgaatcg cagcatctgc atcacgaata ttgttgaatg
    18721 atagctcttt tccatttagc tgcttggctg aagcaattga ataggttgtt gggagcgctc
    18781 tttggtaaaa atctgcagcc tgttgaggat tttcaccgta acgcatgctt tgcttcaaat
    18841 cataggtaag cgtgagcttt tcaggctttg tctcacctgc ttgtcttgta aaataatctg
    18901 caatcactgc atcataggct gcagtatggc gaaaagcttt agctgctaag ctttgacggg
    18961 tttggtaact tgtactgcca gtgctagcca actctcctaa aacgagcgga taatctgtcg
    19021 gatcaaccac taccgtaaca ctagcatgat ttttggccgc tgaacgcagc agtgaaggac
    19081 caccaatatc aaccatatca acagcgacat cataagtgac atctggacga caaatggttt
    19141 ctttgaaggg ataaaggtta acaacaacaa ggtcaattaa ttcaatcctg ttttgctttg
    19201 ctgcctgtaa gtggtgctca atgtcacgac gagcaagtaa gccaccatga atgagagggt
    19261 gcagcgtttt tacccgtccg tccatcattt caggaaagcc tgtcacatcg tcaatagcaa
    19321 cagtgactac accagcctct tcaagagcaa gccttgttcc tcctgttgat ataatatccc
    19381 agccaagatg cttaagctcc ctagcaaggt ccacaatccc tcttttatct gatacgctaa
    19441 ttaaggcgcg tttagtcatt ttaagttctc cttagaaaag tctattttcc tcaatagcag
    19501 tgccatcatc aaacaagtct tctagccttt gttagccacc attggcgcag ctactatgat
    19561 aaacgaaatg ccacaatagg gaaaatagtt attaagctta cacaatcagc ggttaagccg
    19621 ctctactcca agactatcca gtacctctgg atacaattgg tattctgctt catgaattct
    19681 ggcttcaaag ctttcaagag tatcatcact caaacgtggt actcgtacct gtttgatgat
    19741 ttttcctgta tcaataccac tatcaaccca atgaacagtc actcctgact gactaacacc
    19801 tgcttgccaa gcatctaaaa taccatgtgc tcctggaaat tctggcaaat aagctgggtg
    19861 aatgttgatg atttttcctt cgtaagcatc aagtaaggtt gtactcacaa ttttcatata
    19921 gccggcaagg acgatgagat caatctgatg ccgctgcagc aatgccacaa gagtctgctc
    19981 ataggcttgc ttattctcaa agtcctttag ttcaaagctg taggacagaa cacccaaagc
    20041 acaggctcta cttaaaacat gagcatcgca atgatcagaa aaaacaaagg caaccgggaa
    20101 ctgttctgca atcgtttgaa aattggagcc attaccagaa gcaaaaacgg caattcttgt
    20161 catggcttca tcaccacact agcaactgtt ctggtcacaa cgcgaccaat gtcatacaca
    20221 ggctcatcaa gacaggccct cacctgctca acgtgctcag gcttgacagc aagcaccatg
    20281 ccaataccca tattaaaaat ctcaaacatt tcttcatgat tgatcttacc atatgtctca
    20341 aggactttaa aaatgggcag cacaggtaag ctggcttctt caatttcagc ggctagttct
    20401 ttggaaaaca tacgaggtag gttttcaata aagccgccac ccgtaatatg agcgattcct
    20461 gccactaagc cgcttttaat gagtggtaac acagccttga cataaatacg agttggctca
    20521 agaagtacct ccttaagctt ttttccatca agctctggaa gcagctcctc accagtataa
    20581 ccggcaaaaa tacgacgaac caaggaataa ccatttgaat gaactccact tgatgccaaa
    20641 cctaggagat gatctccctc agctactctt gaaccatcaa tcagctgaga tttctcaaca
    20701 ataccaaccg caaaaccggc aagatcatag tcatcttgac catacatacc aggcatctca
    20761 gcagtttctc caccgataag agcagcacct gcttgaacac agccctcagc aatacctgca
    20821 atcacctgct ctaatttggc aggctcattt tttcctgctg caaggtaatc aagaaaatac
    20881 aggggttcgg cacctgctgc aataatatca ttgacacaca tcgccacaca atcctgacca
    20941 atcgtgtcat gcttatcgta ctggattgca agcattagct ttgttccgac gccatctgtc
    21001 cctgaaacca aaacaggctc cttaatagcg gcctttgaca ggtcaaacag gccaccaaag
    21061 cctcctagac cacccataac acccaatcgt ttgctacgct cggcatgctt ttttattcgc
    21121 tcaacaagct catagcctgc ttcaacatcg acacctgatt gagcataagc atttttagac
    21181 attttctcct ccttatttta gctgcctaga tcatttattc tatgttagtc acaaagcgct
    21241 acttcgtcac ctgatcaatg tgaaagctta ccctttcttc taagctcttg agataagccg
    21301 cttcatagtc ataaagcggt gttggatact gaccgtcaaa ataagccaca caaagcccac
    21361 catttggtgc ttttgtatca agtccaatag cctcgataag cccatcaagt gacaaataag
    21421 tcagactatc agcaccgata atatcgcaaa cctcagcagc agtatgatta gctgaaatca
    21481 gctcccgtct tgtctgaata tcaatcccat aaaaacaagg gtatttgagc tcaggactac
    21541 caatcgctac atgaacctct gtagcgcctg cttcacgcag caaattgaca atgcgtcgtg
    21601 aggttgtccc tctgacaata gaatcatcta ccatcacaac ccttttgccc ttgacaacac
    21661 ctgaaacagc tgaaagtttc attcgaactc cctgctcacg aagctcctga gttggttgga
    21721 taaaggttcg ttgggtatat tgattcttga ccaatcccat ttcatttggc aggcctgagg
    21781 cttctgcaaa gcccatagct gctgataatg aggaattggg cacaccaacc acaatatcag
    21841 cctcatgctg aaattcctga gccagtctct ttcccattcg cttgcgagcg gtgtgaacat
    21901 tgaccccagc aatggttgaa tcaggacgcg caaagtaaat atattccata gaacaaattg
    21961 ccagctgcgt gtccgtcgta tagcagtcat aggtgatccc ctgatcatca atgataatga
    22021 cctcacctgg catcacatcg cgaacccact cagcaccaac cacttcaaag gcacaggttt
    22081 cactcgaaac cacccaggca ccatttttca tacggcctat agataatggc ctaaagccat
    22141 tgggatcaag cgctgctatc agctggtgct ctgtcatcag caggtaagca aagccccctt
    22201 taacagtgtt gagcgcctct tttacctttc ctaaaaattc tgggtgatga ctacgacgaa
    22261 tcaaatgcat tagaatttct gtatcagaag aggcattaaa aatagctccc tcactctcta
    22321 acgctttttt caatgaaata gcgttggtca aattaccatt gtggcacaag ccaaattgag
    22381 cgtctgtaaa gcggtataaa aagggctgaa tattattaat ggaagctgcc ccagcagtcg
    22441 cataccgcac atgaccaatg gcagcatgtc cctttagctt gtccagatca gatgaatcct
    22501 taaacacctc tgacaagaga cctacatcac gatgctgatg aagctcccca ttatcatttg
    22561 aaataatacc tgctccctct tggccgcggt gctgtaggct atgaagccca aaataagtca
    22621 cttgagcggc atgtgggtgc ccccaaatcc caaaaacacc acactcctca ttaagagatt
    22681 ttacgtcata tatcatcttt acctctgggc caatgcccct ttaattatga ttgtgtcatt
    22741 aactaggcta gaactaacag ctatcttagc tattacaagg ctatatccaa gatcagtcaa
    22801 tatccacatg gtctcctcta aaataatgca ccgcacttcg gaataaccat tggtccttat
    22861 tgcccggaat attttggaaa agtccctctt cgaagcgctc tgaatgtccc atcttaccga
    22921 taatctgacc atttttgctg gtaagacctt caatagcatt gacagagcca tttggattat
    22981 acctgctatc catgcttggt ttgccatcaa ggtcaacata ctggctgaaa atctgaccat
    23041 tttcacaaag ctctgctaat tctctttctg ttaccacaag cttgccctct ccatgcgaca
    23101 ctgcaacagc atgaatatca cccaccttga cacctgctag ccaaggagaa ttggtattgg
    23161 caatgcgcgt ttctaccatt ttagccacat gctgattggc gtcattataa aacaaggttg
    23221 gactagcctc atgcacagcc tcaaagcgcc catacggcag cagccctgac ttgaccaaag
    23281 cttgaaagcc attacaaata ccgataatca gaccaccctt ttcaataaag gcatcaatcg
    23341 ccgctcgaac cttctcattc agcaagatat taacaataaa tttagctgaa ccatctggct
    23401 catctgccgc tgaaaaacca cctgcaagga agataatatg agcttgatga atatggtcaa
    23461 ccatcgtgtc aactgaaacg tcaatagctg cctcattcaa ggtaacaaaa ggcaccaagt
    23521 tcacccttgc accctctctt tcaaaggcct tagccgaatc atattctgag ttagttcctg
    23581 gaaaaactgg aatatacaca actggctgaa ctattttttc cttaaactga gtagcaagtg
    23641 ctgttgtcac tacaggaaca ggctgtaagt cacctgcctg ctgaaatacc gttgggtaaa
    23701 cctgctccag gctcccctca aaagccttta agagacgatc tccagatagc ttgacatcat
    23761 tgacaatcaa tgtaaagtca ctagtggtct gaccaagcct gatagcacct gcaatctcct
    23821 cttttgatgt aaagacaaag ccgccaagct gagctgttaa gctcctgtca agctctggta
    23881 atgtcacaca agcccctaac tgattaccaa aggctgccag agcaagtgtt tcaataatac
    23941 caccgtattt aacagccgaa gctgagctaa tattatgctt tttctgaata gcctcaaaag
    24001 tcataaaatt agattttatc aactcaaaat caatcacttc cgaaatagcc tgccctggaa
    24061 tatagtaaat attctcgcca gcagctttaa attctggtga aaggatatga tctacatgag
    24121 cagtcgtcac accaaaggca accaaggtcg gcggcactgt caattcctca aagctaccag
    24181 acatcgaatc cttacctcca atagaaggca agccaagctg cacctgtgct tcaattgccc
    24241 caagcaaagc tgccaccggc tgaccaaagc gctctgcctg cttatccatt ctttggaaat
    24301 attcctgata tgaaaagcga gccttatgcc aatggctacc tgttgcgacc agacgagcag
    24361 ttgcttcaat cacagcataa gcggcaccat gataaggtga ccattcggct atataagggt
    24421 gatagccttg agcgatgaca gaggctgtct ttgtcactcc atgttgaact ggtaatttct
    24481 gaacagaacc ttcaacaggt gtcatttgat agcgcccacc aagtggatgt attactgtgg
    24541 agcgacccac tgagctatca aaaagtgttt gcaagccctt ttgactagca tggttcaggt
    24601 ctgataagac agcaatggta tctgcttcaa gtgtctcagc agtagtttga cgggcttctg
    24661 gtattggcgc accactgtca acaaccttag cagcaacaga cacgcgcaca ccatttgtct
    24721 ctaaaaatga gcgttcaata tcaacaatcg tttgcccatt ccaggtcatg acaaggtttg
    24781 gcttttcagt aacagttgcc acaacagcag catggatatt ttccttatga caggcgctca
    24841 taaaggcctc taaatccttt ggataaatca cgacagccat acgctcttga gattctgaaa
    24901 tggcaatttc tgttccattt agtccagtat attttaaagg aatcttatct aagttaatgt
    24961 taagaccagc agcaagctcg ccaatggcta cacaaacacc accagcacca aaatcatttg
    25021 acttcttgat gaggcgtgtc acatcgccac gacgaaaaag acgttggatt ttacgctcct
    25081 caatggcatt tcctttttgg acctctgcac cagctgtttc tacagactca actgtctgaa
    25141 ccttagatga tcctgtcgca ccaccaatac catcacgtcc tgttttccca ccaagcaaaa
    25201 ccaccacgtc acctgtcctt ggcttttcac gaaccacatt ttccttgggt gcagcaccaa
    25261 ctaccgcacc aagctccata cgtttggcaa caaagcctgg gtgaaaatac tcacgaacat
    25321 aggtcgtcgc tagcccaatt tgattgccat atgacgaata accatgtgct gctcgcctcg
    25381 aaataacctg ctgtggtaat ttgcccttac gagtctctga cagcgggctt gtaatgtccc
    25441 ctgcaccaga aagccgcatg gcttgataaa cgtaggaacg gcctgacaga ggatcacgaa
    25501 tagctccacc aatacaggtt gcagcacccc caaagggttc aatttctgtt gggtgattat
    25561 gtgtttcatt tttaaacatg agcagccaag gttccttgac accatcaaca tctacctcaa
    25621 tttccactga gcaggcattg atttcatctg aaacctccaa atcctctaaa cgaccattag
    25681 ctctttcata acgtccaaaa atggtagcca tatccataag cgtttgaggc ctttcagatc
    25741 gacctagctc atcacgcata gcaaggtagg tctcataggt agcttggagc tgcttttcaa
    25801 aatgagaagc tgaaaaatca agcgttttta gctctgtttc aaaggttgtg tggcgacaat
    25861 gatcagacca atacgtatcc aaaaccctta gttcagtctc tgttggaact cgcccctttg
    25921 acttgaaata atcctgaata aacagcagat cctccacttc cattgctagg ccctgttcag
    25981 acttgtaacg agcaaaatct ttcgctgtat aatcattaaa aacatcaagc gttggaatca
    26041 ctttatctgc tactgaaaaa tcctgatcat caagaccggc taatatgtcc ttaaacctag
    26101 aatccactgg atttaacaag tactgcttta aagtttctaa ttcttcagca gcaatgtctt
    26161 gattgaccaa ataaagctgt gaggtcaaaa cagtcacatc agttgaggct cctaacaaca
    26221 ataaggcttc ctgagagctt gccgcacgct gatcaaactg tccaggcagg gcttcaatcg
    26281 caaaaaaggc ataccttttt aaatctgctt gtacagcttc ttctgacaat acctgatcag
    26341 tgacctgctc agagaaaaca tgctttatag ctgctaaaag cagctcctga tccaaatgaa
    26401 acacatcata aacctgcaca atacgcaact caactagtgt ctttaactgc agctgatgcc
    26461 tcaattcctt taacagggcc tgggccttaa tctgaaaatc agcccttttt tcaacaaaaa
    26521 ttcgtttatt catagttaac ataccaaatc caatcagaaa acaacccaaa ataaggacta
    26581 tctccagtaa caggtagcct ctcccagaca gcagctcaac tagtctgaac tgatttattt
    26641 tcttacatga cggacaaaaa aactcccttt cttagctgac aacaaataag ctgatcttta
    26701 ttgatccaat gctcttagcc tttccaaaac agtctcatag gcttgcgtca aactgccaag
    26761 ctgacgacga aaaacgtcct tatccatgtg acggcccgca ttatcccaca agcggcaatt
    26821 atccggagaa aactcatcag caaggataag catcccctcc ttatcaaagc caaattctag
    26881 cttaaaatca accagtgtca acccaacact agcaaaccac tctttcagat aagcattaat
    26941 acgatgcgtc tcttgcttga tgtaggctat ctgctcatca gtcgcaagct ttaaaaagct
    27001 gacatgctca tcattaatga aaggatcatc taaagcgtca ttcttgtaat aaagctcaat
    27061 aattggctcg tccaaagcct gaccttcttt aacaccaaag cgctttgaaa atgagccagc
    27121 agccacgttt cgtaaaacaa cctccaaagg aataatcgca acctttttat ttaactgttc
    27181 tgtctcggac aattgcttaa taaaatgagt tgatacgcca accctattta gcctatcaaa
    27241 gattaaggca gaaatctgat tattaaggct cccttttcct tcaatcattt ccttatgtgc
    27301 tccatttagc atagtaacct gatccttgta gacgattaag acaatcccgt catcggctgt
    27361 ttcatagata tcctttgcct tacctgaata aatgagttga ttagacacct ttttgttcgc
    27421 ctttctttgt gtttaatatc taaacaatac cacaaacata ctaaatattc aatatttatt
    27481 tacatttaaa aaaaacaaac ttataacgtt cgtttttgta aacaaaaaaa gagctgatgc
    27541 ccttttaaaa ctatttagct ttggtttaaa cgcttgacca aataatttag catatctccc
    27601 atagatacca tgccatcaac atcctcatca ggaatatcaa taccaaattc atcttcgata
    27661 ttaataacaa actctaccag ctcaatagaa tctacgccta aatcatcttt tagtgctgtt
    27721 ttttctgtaa tatcaaaatc tatacgactt ctttgcttct tgattaatgc gatgattttc
    27781 tctaaaataa cttcctcagt catttgcgtc actctcctta gaaaactcct caactaattg
    27841 accaactaca tctgtttcta gcatcgtacg aacctgcttg atggtatgaa aaatagcctt
    27901 ggcatcacta gaaccatgtg atttcacaag aggtgcttta aggccaaaca atacagcccc
    27961 acccgcacta gaataatcta aagtatcctt taagtcataa agactaccct tcaataaaag
    28021 agctccaagc tttgccttaa caccacctac tgctatagct gatttcaatt gtcccataat
    28081 actcatagca gtgccttcaa tcgacttcaa aacagcattt cctgtaaagc catctgctac
    28141 cacaacatct gccacgccag acatcaaatc tcttgcctca acattcccaa taaactgtag
    28201 gctgctgtct gaagctaaaa gcttatagac ctccttgcga agagaatctc ccttagttgc
    28261 ctcagtacca ttattaagca agccaatccg aggcttggca ataccacgca catgttttgc
    28321 ataaaaagag cctaaaatag catattggtg taaatgctct gctgtgtttt cagcattggc
    28381 acccaaatct aacatgtcaa agcctgaacc atcaaccgtt ggcagagttg acagcaaacc
    28441 aggacgatcc actcccttga tacgaccaat aataaacaaa ccagcagcta acaaggcgcc
    28501 tgtattacct gccgaaagaa ctgcatcagc ccgaccatcc ttaactgccc ttgcagctaa
    28561 aaccatagaa gcattcttct tacgacgaat agcctttgct ggctcatcat cagaattaat
    28621 tttttcatct gtatgaacaa tggacacacg atctgattta actaggtaag actcaatcct
    28681 tgattgatcg ccataaagct gaatttcaat atctgaaaag gattctatcg cctgattaac
    28741 accctcaaca atagctttag gggcataatc accacccata gcgtctattg caattttctt
    28801 catttttgct cctttaatcc tatttttctt aacgaaaaat atcctagaga ataacgtaac
    28861 tattatagca tattccccag acaattccca taaaaggaca aatccacacc tgaatagctc
    28921 acaagccctg cttgtttttc ataatatctc cccacttagc caaatcatca ataaaaacct
    28981 tactttttag acgaataccg acataatcct catacaaggc atcaataaaa agacgaagct
    29041 tttttttcat accagtattc acagaaatag tctttagctc atcaatatta agcgtttgaa
    29101 aacgattaag caaataaatc acattgggat ccaagccata tcgcctctca tcctcatggt
    29161 aatgctgcgg acaaaggaca cctgaatact tatgagaaaa atcaaaaggc agattggttc
    29221 tgtgacaaaa aacacaatca tgaaaattca ttctcacccc aaaacgatcc aaaatctgga
    29281 tttcaaagat attcgttaaa atgtcataat ctagcccttc ttccatcaga tcaagagtct
    29341 ttttcaaaaa agcaaacaac tgaggatcag gctcattatc tggaatagcc gcatcagcca
    29401 gagccaagac ataactagca taggatagcc taaaaaaatc ttcattgatg tgccgataag
    29461 cctccacctg attataatcc tctatataag aaaggcttga atcattgatt ttcaatagaa
    29521 aatcagcagc cgttaaaggc tggaccacag gagctagttt agaacgacca atatgtttca
    29581 cgaaaaacat acgcttgccc gccgcttctg taaatatttt tacgagctta tcatcttcac
    29641 gatagttttt attgtacaag acaataccaa gtgacctctg aatacgcata tatctccata
    29701 accaagcttc tcagctagta ataatgcctt tcttactaga cctttaaaac accttaaata
    29761 cagctatatt atacccaaaa tccaggaaaa ttgcatgact aacactgtac ttaaggctca
    29821 taacaactct gagaataaga agctcaacag tcactagcca taactatatg aatcataggc
    29881 tagctatttg aacacagcac ctacacgtga ctttttgcta taatagctca gcacctacca
    29941 caagacagtg aagcctatct atagcgttaa atcaaacact gctttggtag tcaaatagcc
    30001 ttttaaaaca taaaaaagcc taaggcttac tacctcaggc taaccttatc atttccctaa
    30061 ttcaaatagg ggtgacaatg gacgtttttc atggatacga atgatagctt ccgcaatcaa
    30121 atctgcaata gagatttgtt caatcttatc aatcagtctt tcttctggta aatagatcgt
    30181 atccaaaaca atcaattttt caatcgctga tttttgaata ttatcaagag ctggtcctga
    30241 cagcactggg tgagtacatg atgcgtaaac tgctgttgct cctgcttcag caagcgcatc
    30301 agcagcatga cagatagtgc cagcagtatc aatcatatca tcaatcagaa tacatttttt
    30361 accttcaaca ctaccaatga tattcatcac ctcactggta ttcattttat caacactacg
    30421 acgcttatca ataatagcaa ttggcgtttg gaggaattgg gccagcttac gagcacgcgt
    30481 cacaccacca tgatctgggc taacaacaac aacgtcatca cctactagac catgacgatc
    30541 aaaataatca gcaattaaag gtgctcccat gagatgatca acaggaatat caaagaagcc
    30601 ttgaatctgc gcagcatgta aatcaacagt caataaacga tcaacacccg ccacctctag
    30661 catattagca actaatttag aggtaatagg ctcacgcgaa cgagccttac gatcctgacg
    30721 agcatagcca taataaggca ttaccacaga aattttctca gcactggcac gctttaaagc
    30781 atcaaccata attaaaattt ccattaggtt atcattaaca ggcgagcttg ttgactgcaa
    30841 aataaaaaca tggtgtccac gtattgattc ctcaatattg acctgaatct caccatctga
    30901 aaactggcga accgtagact tcccaagttg aattcccatc gcagcagcaa ctttttctgc
    30961 taattccttg tttgacgata atgcaaacag ctttaaatca gaataagaca ttttttcctc
    31021 caaagttttg atcctatacc attttaaccc ttttcaatca atttttcaat ggaaataaaa
    31081 aggtaagaat cctgattctt acctttactt attttctaat ttggataaat atacgataca
    31141 gcacctgggc taaaccaacc acgataattg ccaatagatt gatttccagc atagttggct
    31201 tccataacct gaatctgtcc accctgaaca cctgttacgt aagcaacgtg accatagcca
    31261 ccatcattcc acacaacaac agagccaacc attggtgttc cacctacacg gaaacctgct
    31321 gccgctgcac ttgatgccca ttgaccacca tttccccaat aattgccaac ccaaggagct
    31381 aaagccttaa ctccccaagt acattggccg acagggtacg gattagaagg atcatacgca
    31441 tacgacaccg ctggtgctga aaccatagct gctggcgcca caacaggctg tgcctgcgct
    31501 ggagctggtg ttggtacggc ttgagtcact gctgcttgag ctgccgctac agactgtgct
    31561 tgagcttgag cctgtgctgc tctggctgct gcttcctgct ctgcctgagc cttggcttga
    31621 gctgctgcct gctctgcagc ctctttacgg gtaatcaagc tagccttctc gtcctcagca
    31681 gttgctaatt gaagcgccaa atctaccttg gcaacctcta aatctgcttg ttgagtcttt
    31741 aaagctactt ggtttgattc aattgctgta atatttgaag caattgtatt aatcgcttct
    31801 tgattttcct gttgcttttc ttcaagagaa agcttatcag ccttttgctt ttccaacatc
    31861 tgtgcattgg ctgacacagc tctattaata gcaaccaaac gagtaataac gtcagaaatt
    31921 gacttagaat tcaaaagtgc attgaggtaa cctaacgtat ttcccttttg agcactacga
    31981 gcctgtcctt ttaacttttc attacgagca ataatttgac tggcaagcac ttgaatctcc
    32041 tgctcaaact gagcagatcg cgcttcaagc tcaccatttt tagcgactaa cctttcttgt
    32101 tcagattgta atgagctaac ctgactttgc aaagtcttca ttctatcctg cgcagctttt
    32161 tgttctttat ttaaattaga aataactgaa ttttgcaacg ctattttgga atctaaatca
    32221 tccgctccca ctgtagttgc tgttccaagg gtcacaccgc ttacaagaac cgctgataga
    32281 attctttttt tcatactaaa aaaattactc cttttcgata agacacatta tattctatca
    32341 aaaaatcaag cgtttaatgt tacgcatctg ttacagttgt atgtaataat caataaaatt
    32401 gacttaatat taattttcta aagcaaaaca aaataaggag attgacgatt aaagtcggag
    32461 caagctgaaa cgtcattaca taaggaaaag tcatatcagt taactgatag ctgtttgcca
    32521 aaataaagct tgatacatct acaagaaaca tataaagagt aaagaaaagg aaaaattgta
    32581 gctgactaat ggaaccagaa aagaacctta atagccctag aacgatcatt gttccaaaag
    32641 gcaaggcaag agacaaaatc cctatatgat caaaataata ataatcaaac aataatccta
    32701 aaagaagaga gaagaaacaa ataactccct tagatctaaa cgctaccata aggatcagga
    32761 aaaacagtaa aaagaggtgt gatactaccg agtaaccctc aggtaacatt gagctgatca
    32821 ggtctgacac gtgtgcatca acaaaaaata aaagaaaagg caaaaggact aatagctctg
    32881 aagatttttt catattcact cttttccaac aacaagaaca tagtcaagat tatcagtatc
    32941 agcatacaat tttataaaaa tacgacgctt tagcttatca gcagcatttt taaagcccgt
    33001 aacctttcca acaggaatat ctgccacagt ctcaccatct aatccacttg tataaacctt
    33061 agcatctaat gatattgact cattggaatt aaattcgctg gcaaccattg ttttactttc
    33121 tgatttaaat gcctttaaat tgccataaat caccttatcc ttatctacaa ttttaatcgg
    33181 caactcaata ttcttcccag atgttaacaa ttcaacatga gcagatgact ggctaacagc
    33241 tgtaacacga ccaataagtc caagctctga agtaaccaaa gacttctcct taatttccct
    33301 tttgccgcta tcaatgacca gcgatttatt ccagctataa ggatttcttg atatcattct
    33361 ggcagcaaat tgattatcag taccataatc caaccctaac agttccttga gctctcgatt
    33421 ttcagatttt agcttgtcaa cctgtaactg atccaattta taggacctaa gttccttttt
    33481 taaatgctta ttttcagaaa aagcagacat caagctatct aattcctttg caccctcctt
    33541 tataacagca aaaggcttag acataatagc atcaattt
//
LOCUS       DARYSY010000022        33518 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYSY010000022 DARYSY010000000
VERSION     DARYSY010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33518
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            93..494
                     /locus_tag="TVR04_000926"
     CDS             93..494
                     /locus_tag="TVR04_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HEL1269627.1"
                     /translation="MIVKKKVIILLGIVAILVIGGMAMFNSFTGKDEPRYKHEQDRMV
                     EYLVKNYKNIEKVEFTSYSKNHSTGTWSSNAIINDKVYVTFNVNNLGASEEIGFGQHV
                     SQSDGNRLIKREISSEKNRKSVEVIYYRKDK"
     gene            491..1693
                     /locus_tag="TVR04_000927"
     CDS             491..1693
                     /locus_tag="TVR04_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269628.1"
                     /translation="MMFTEQEYNYLSDQVYEVDKKKNSTPWEEGDELTKFGKFYKVLK
                     AEDNPDNGMQAMAVAPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLC
                     THEGPDSFKVVKSQLSTAKAFSDHIRTRYPNAAISYTGHSLGGYLALITAAHAKQPAT
                     VFNAPSSVNNLSKEAIDFVKANKELYHSYRINNDYIGNLGTYLGDDELGISRWVDGKA
                     GIGRHSLAAYRFNSKGQVIDRKGRPAAAQSPALATLSSKLTEYRLLKKKYAASNGISS
                     SEEFYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEALHQKTRDMPFFVSELS
                     WAELEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKTLKEQLEEGIERTIATD
                     QKLGGDFS"
     gene            1690..2082
                     /locus_tag="TVR04_000928"
     CDS             1690..2082
                     /locus_tag="TVR04_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269629.1"
                     /translation="MTALEKIRATIRQKEEELEELQEHYHQERLQMEAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQCRKMSQQE
                     EEIAHHYRSKRQAIEKDITALRRQWREG"
     gene            2098..2382
                     /locus_tag="TVR04_000929"
     CDS             2098..2382
                     /locus_tag="TVR04_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269630.1"
                     /translation="MIAIEMILTGQEPIRALKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALERAIKTQNRGYSSLM"
     regulatory      2867..2992
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3065..3643
                     /locus_tag="TVR04_000930"
     CDS             3065..3643
                     /locus_tag="TVR04_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1269631.1"
                     /translation="MSKTHRLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQAYLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            3633..4283
                     /locus_tag="TVR04_000931"
     CDS             3633..4283
                     /locus_tag="TVR04_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1269632.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLQLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVAVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            4474..5397
                     /locus_tag="TVR04_000932"
     CDS             4474..5397
                     /locus_tag="TVR04_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1269633.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDQEMERRNSWQGCKLKG"
     gene            5410..6195
                     /locus_tag="TVR04_000933"
     CDS             5410..6195
                     /locus_tag="TVR04_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1269634.1"
                     /translation="MKQRLIAGKELSLPPVLKKLLQNSLIYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            6205..6762
                     /locus_tag="TVR04_000934"
     CDS             6205..6762
                     /locus_tag="TVR04_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1269635.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     TLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEALLDYIGQLDQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            6890..8224
                     /locus_tag="TVR04_000935"
     CDS             6890..8224
                     /locus_tag="TVR04_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1269636.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVVSAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            8301..9092
                     /gene="pflA"
                     /locus_tag="TVR04_000936"
     CDS             8301..9092
                     /gene="pflA"
                     /locus_tag="TVR04_000936"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1269637.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            9582..10517
                     /locus_tag="TVR04_000937"
     CDS             9582..10517
                     /locus_tag="TVR04_000937"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1269638.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGVDQVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENGVDVPKDIAGLLLSGLISDTLLLKSPTT
                     HASDHRVAVELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     ETAFDFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            10584..11237
                     /locus_tag="TVR04_000938"
     CDS             10584..11237
                     /locus_tag="TVR04_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1269639.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(11342..12340)
                     /locus_tag="TVR04_000939"
     CDS             complement(11342..12340)
                     /locus_tag="TVR04_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1269640.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNPLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIILVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(12337..13362)
                     /locus_tag="TVR04_000940"
     CDS             complement(12337..13362)
                     /locus_tag="TVR04_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1269641.1"
                     /translation="MTAQHHTSPKLTKEAPLWLILTFISLTLVLAIYCSLRFGSVSLS
                     HQELFHILLGKHGLGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFFPHLHYSTIILLSLLGSLLATLLILSLAYQTRKGYTQIRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLVLS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(13373..14311)
                     /locus_tag="TVR04_000941"
     CDS             complement(13373..14311)
                     /locus_tag="TVR04_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1269642.1"
                     /translation="MKKLLLMLTVFVTAVTLVACSSQNKSQENTSKASLSHKPKIAGV
                     TYYGDIPAKPKRVVSLAATYTGYLAKLDLNLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALKPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETN
                     QWLADWKQKTSDYEKEVKKVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQAFHYD
                     APEKVTKEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSNGANH"
     gene            complement(14336..15115)
                     /locus_tag="TVR04_000942"
     CDS             complement(14336..15115)
                     /locus_tag="TVR04_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269643.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKALARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGRLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGDIK
                     YSGEVNQVMTPEMIQDIFQIKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(15375..16820)
                     /locus_tag="TVR04_000943"
     CDS             complement(15375..16820)
                     /locus_tag="TVR04_000943"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1269644.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQHKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGKSFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVINSGMEHFHILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKLSGDYTIQLIGSFNQENAMAAGLACLRLGASLEDIRLGIAKTRVPGRMEV
                     LTMTNQAKVVVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVHIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQSKEDAL
                     IIAGKGADAYQIVKGQKAAYAGDLAIAKSYL"
     gene            16906..18537
                     /locus_tag="TVR04_000944"
     CDS             16906..18537
                     /locus_tag="TVR04_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1269645.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLVFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLIDQWTFVNT
                     MTLFTNYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYVKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEEQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTFGLLVPIYLMY
                     RRLHQVTRFNRRLLHKRILLTVIETALMGLIVLLSSWLLGYVIKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLVTRQLDKLIGSRAARYRQKLGL"
     gene            18687..19316
                     /gene="upp"
                     /locus_tag="TVR04_000945"
     CDS             18687..19316
                     /gene="upp"
                     /locus_tag="TVR04_000945"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1269646.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            19547..20137
                     /locus_tag="TVR04_000946"
     CDS             19547..20137
                     /locus_tag="TVR04_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1269647.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            20232..20678
                     /locus_tag="TVR04_000947"
     CDS             20232..20678
                     /locus_tag="TVR04_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1269648.1"
                     /translation="MLIINEELFAIEKAILQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKSCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            20679..20963
                     /locus_tag="TVR04_000948"
     CDS             20679..20963
                     /locus_tag="TVR04_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1269649.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            21279..21914
                     /locus_tag="TVR04_000949"
     CDS             21279..21914
                     /locus_tag="TVR04_000949"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1269650.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            21928..22803
                     /locus_tag="TVR04_000950"
     CDS             21928..22803
                     /locus_tag="TVR04_000950"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1269651.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRTCQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GKRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNRVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAVNAQQLTVFSENTRLLELMTQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMVLTLLTLILAKDYHRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            22800..23600
                     /locus_tag="TVR04_000951"
     CDS             22800..23600
                     /locus_tag="TVR04_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1269652.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDHKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            23593..23916
                     /gene="yabA"
                     /locus_tag="TVR04_000952"
     CDS             23593..23916
                     /gene="yabA"
                     /locus_tag="TVR04_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1269653.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLADIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            23921..24787
                     /gene="rsmI"
                     /locus_tag="TVR04_000953"
     CDS             23921..24787
                     /gene="rsmI"
                     /locus_tag="TVR04_000953"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1269654.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLTCYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPIKGECLLIVAGANQADASESAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            25290..25484
                     /locus_tag="TVR04_000954"
     CDS             25290..25484
                     /locus_tag="TVR04_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1269655.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGATLGFPVCGVACGS
                     IGAKTGVTLWAWATGVTGGF"
     gene            25542..25742
                     /locus_tag="TVR04_000955"
     CDS             25542..25742
                     /locus_tag="TVR04_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1269656.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            26410..26991
                     /locus_tag="TVR04_000956"
     CDS             26410..26991
                     /locus_tag="TVR04_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1269657.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITETHAAGGQADKAAGISEDKAKELAFKDASITAADAQRLKLTKETDDGRVV
                     YDIEFDAKDQEYSYTIDANSGEILEKSSEPVYD"
     gene            27329..28834
                     /gene="glpK"
                     /locus_tag="TVR04_000957"
     CDS             27329..28834
                     /gene="glpK"
                     /locus_tag="TVR04_000957"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1269658.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNSVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTREDFIKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWEDMETLKQLNATGQLFKASMSDSRREKLYQGWKRAVKATQFFTEEL"
     gene            29008..29652
                     /gene="fsa"
                     /locus_tag="TVR04_000958"
     CDS             29008..29652
                     /gene="fsa"
                     /locus_tag="TVR04_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1269659.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            30036..32024
                     /gene="tkt"
                     /locus_tag="TVR04_000959"
     CDS             30036..32024
                     /gene="tkt"
                     /locus_tag="TVR04_000959"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1269660.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(32206..33495)
                     /locus_tag="TVR04_000960"
     CDS             complement(32206..33495)
                     /locus_tag="TVR04_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269661.1"
                     /translation="MYRYGVCSAAIVLIASARIGATAHAEEREASQLQQLLSQFPKVD
                     KTLQIQNGISNVYTTGSIRKYLSELEEYFKNYLGEINFELTKPGPAGPRGERGPQGPA
                     GPAGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQGPRGDKGENGAPGEQG
                     PIGPKGETGPAGKQGERGPKGDKGERSEKGEQGLRGEKGEQGLRGEKGDQGQRGEKGE
                     QGLRGEKGEQGQRGEKGDQGQRGEKGEQGLRGEKGEQGQRGEKGEQGQRGEKGEQGQR
                     GEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGENGEQQPKGDQG
                     KDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTLSKSVAPTS
                     KKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
BASE COUNT         9215 a         6702 c         8036 g         9565 t
ORIGIN      
        1 agccgaagat aaccccgaca atggtatgca ggctatggtg tcaaagagga atgggaatgt
       61 gctagcctta aattataaat taaggaggtt ttatgatagt aaaaaagaaa gtcatcattt
      121 tactaggaat cgtagcaatt ttagtaatag gaggtatggc aatgtttaat tcatttacag
      181 gtaaggacga accaaggtat aaacatgagc aggatagaat ggtagagtat ttagttaaaa
      241 actacaaaaa tatagaaaaa gtggaattta ctagttattc aaaaaatcac tctacaggta
      301 cttggtcaag taatgcaatt atcaatgata aagtatacgt tacctttaat gttaataatt
      361 taggagcgtc cgaagaaatt ggatttggac aacatgttag tcagagtgat ggtaataggt
      421 taattaaaag agaaatttcg tccgaaaaaa atagaaaatc agttgaagtc atatactaca
      481 gaaaggataa atgatgttta cagaacaaga gtacaattat ctttcagatc aagtatatga
      541 ggttgataaa aagaagaatt caactccttg ggaagaagga gacgaattga ctaaatttgg
      601 aaaattttat aaggtcctca aagccgaaga caaccccgac aatggtatgc aggctatggc
      661 agttgcacca ataaaagatg gcaaagagga tagaagtcac attgtcattg cttatgccgg
      721 gacaaatagc agtgatatac gcgatattga caccgatatt caatccgttg tttttggaga
      781 tgatcaatac ctgtgtaccc atgaggggcc tgattctttt aaagtagtca agagtcagct
      841 aagcactgct aaagcctttt ccgatcacat caggacaagg taccctaacg ctgccatctc
      901 ctacaccgga cattctctgg gaggctatct ggcactcatc acagcagccc atgccaagca
      961 gcctgccact gtctttaatg cgccaagctc tgttaataac ctctccaagg aggctattga
     1021 ctttgttaaa gccaacaagg aactctatca cagctaccgc attaacaatg actacattgg
     1081 aaacctaggc acttaccttg gagatgatga gctcgggatt tcaagatggg ttgatggtaa
     1141 ggcgggaata ggacgtcata gcttagccgc ttatcgcttc aactcaaagg gtcaggtgat
     1201 tgaccgtaag ggtcgtcctg ccgctgctca atcacctgct cttgctaccc taagctcaaa
     1261 gctaaccgaa taccgcctgc taaagaaaaa gtatgcagcc tctaacggta ttagcagttc
     1321 agaggagttt taccttgatc agtttcaggc tcgagcagtc gcacaggctt tggagcagac
     1381 cactcagctt gcccaagagg agatcattgc tcgtcggaag gaggcggttg cagaggcaga
     1441 ggcacttcac caaaagacaa gagacatgcc cttttttgtg agtgaattga gctgggcgga
     1501 gctagaggag gcttatgccc aggcaggagt gacctatgac agccttgtgg gtcagaccaa
     1561 aaggcatttt gatgacaagg ttactcaagc tagaggactg gccacaaagt tcaagaccct
     1621 caaggagcag ctagaggagg ggatcgaaag gacaatcgct actgaccaaa agctaggagg
     1681 cgacttttca tgacagcatt agagaagatc agagctacta tccgtcaaaa ggaagaggag
     1741 ctagaggagc tacaggagca ctatcatcaa gagcggctcc aaatggaagc agcccatgac
     1801 gagctaagag gcaactacaa ccagctgcag cagctctatg cctctagcta tcaggccgtt
     1861 agcagctacc tcagacatta tgatgctagc ctgataacag accaatatac cgttttaacg
     1921 aggcttattg atgactacca gcaccgaaca gagcagtgct atcacgagca atgtcgcaag
     1981 atgtcgcagc aggaggaaga gattgcccat cactatcgca gcaagcgaca ggctatagag
     2041 aaggacatca cagcgctgag gcgtcagtgg cgtgaaggtt aaaggaaagg agataagatg
     2101 attgctatag agatgatttt aaccggacaa gagccgatta gggctttaaa gaaagagctg
     2161 gataggagat tggttcagtc catatgtgcc cccttgacct taggtcgcct tcatgccctt
     2221 caaaggcgct atgacagtga ggtatctcgg attgctacag acaccgcaga tcatattcag
     2281 accattgtca atcagctaga tagcagcatt agagggcaag gcaggacagc actagagcgg
     2341 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa gggcttactg
     2401 tcctaccagc tgtctaggct tttacagcag tcaccacact gctagacttg tgatgtgagt
     2461 agcagtaaga agcaaaggcg ctgccctaga gggctgatga atcaccatca cccgtttgga
     2521 agcaccagct gtgctaatgc ttttctaaag ccaaaaagaa aaaaactccg attggagttt
     2581 tcattggtta ggtgtgtcta tgactgtaaa ggggacaatg gtagtaatac tagagcaggt
     2641 tattggagat ttcttctagt ctgctctttt ttgccttgag ctagtgccat gtcacaggga
     2701 gatatagctc gtagggagct ttgcggccta gggtattttt gcggtctcat actgtttttt
     2761 ttgctgttgc tttcacttcg ccttttttac gtgatgtctt gtgtttttgg acaagctagg
     2821 cttcaaaaaa atgtcttgcg ctataggttt aaatttgcta tgctataaat gtcttcaggg
     2881 cagggtgtaa ttcccgaccg gcggtgacta gtgcagctag aagtccgcga gcgcaagctg
     2941 atgtggtgtg attccacaac cgacagtaaa gtctggaaga gagaagaccg ggtttttgag
     3001 ttgacttttt gcctgctcat acgaaggagc ttctttcaat ttgtcaaaat tggaggaatt
     3061 ttttatgtca aaaacacatc gactggtgat ggttgccatt ctttcagcca tatccttttg
     3121 cctgatgttt gtggggtttt ccattattcc aggagccagc tttttaaaga ttgattttag
     3181 tatcattccg attttgttag gcttggtctt gatggatcta aagcaagctt acttgatttt
     3241 agcggtgagg accttgctta gactagcctt aaacaatcat ggcgttaatg atttgattgg
     3301 tataccgatg aatgttatag cagttgcgct ttttatcact gcctttgcct tgatttggca
     3361 tcgtcagaaa gggctggtca cctatgtact agctagtctt gtggggacag ggctgttaac
     3421 gcttggtatg gttgtcatga actatgtctt tgctattccc ttatatgcca agtttgctgg
     3481 ctttgatatt aaagctttta ttggtactgc tcgctacata tttacaatgg tcattccttt
     3541 caaccttttg gaggggctaa tatttgcaat tgtcttttat ttcgtgtata ttgcaggtaa
     3601 acccatttta gagagatatc cgaattcata tcatgaaaca taaacaacaa catctgctat
     3661 tgtcttcctt tgctatgctg ctatttgtgg tgcttggcta tattgttaaa ttttttcccg
     3721 aagacctaac gtcttttgat agtcagcttc agttagccct aagaggtcat ctgcctgaag
     3781 ggctaaccca gttttttaaa gggatcactg tagctggaaa tgttagtaca caggcagtga
     3841 ttgttgctgt tgctgtgctg gctttattgg ccttgagctg gagagcggag gccttatttg
     3901 tcctatcaaa tggtgttttt gcggcccttt tgatttgggt gctaaagctc ttgtatcaaa
     3961 gaccaagacc cagcattgag catttggtgc atgcttctgg ctattctttt ccgagtggcc
     4021 attcgatggg gagccttttg attattggaa gcctgctgat tatttgtcat caaagattgc
     4081 agtcagcctc cttacgctgg ctggttgata tagccctttt ggccttgatt ttgctgatag
     4141 gcttgtcacg catttatctg ggagtgcatt atcctagcga tgtgttagct ggctatgcct
     4201 taggctttgg catacttcag ctgctttatc ctttttatga tcaaaagcgc tttgaatggc
     4261 gttttcagct aaagcaaaag taaatccagt gatcagtcag ctgtatggtg cgttacagat
     4321 cagttctaga aaagctagtg attgaagaca ggtctcttcc agaggtcttc ttcaatcctt
     4381 tttagttgcc ttgctttggc tcatcaatca gagaagtagc agccaattga gatcttctgc
     4441 tgttaatcgg gggatttgtg ctacaataga ggcatgacaa aaagatatca gaccttaaat
     4501 gagtattatc gtcgtttatt tggtgctaaa attttcaagg tgcccattga tgctggcttt
     4561 gactgtccta atcgtgatgg gacagttgct catggtggct gcaccttttg taccgtttct
     4621 ggctcaggtg atgcgattgt ggcgcctgat gcaccgatca gggaacaatt ttacaaagaa
     4681 attgatttta tgcatcgcaa gtggcctgag gtcaatcagt atttggttta ttttcaaaat
     4741 tttaccaata cgcatgataa gctagaggtt attcgcgagc gctatgagca agcaatcaat
     4801 gagcctggcg ttgttggtat caatatcgga acaaggcctg attgtttgcc agatgagacg
     4861 attgcttatt tggctgagct atcagagcgc atgcatgtga cagtggagct tgggctgcaa
     4921 acaacttatg aagccacctc ccagctgatt aatcgggcgc attcttatga cttgtataag
     4981 gaaacggttc agcgtctgag gcagtaccct aacattaaca ttgtgtctca cttgattaat
     5041 ggcttgcctg gtgaaaccca tgagatgatg atcgaaaacg ttagacgctg tgtcacagac
     5101 aatgatattc aaggcattaa gctgcatttg ctgcacctga tgaccaatac gcgtatgcaa
     5161 agagactatc atgagggacg cttgcagctc ttgagtcaga aggactatgt atcgattatc
     5221 tgtgatcagc tagaaatcat acctgagcat atcattattc atcgcatcac aggtgatgcg
     5281 cctagggaca tgctgattgg tcccatgtgg agcctgaata aatgggaggt tttgaatgcg
     5341 attgatcagg aaatggaaag aagaaatagc tggcagggct gcaagcttaa gggctaatcg
     5401 gagaaagcaa tgaagcaaag attgatagca gggaaggagc taagcctacc gcctgtttta
     5461 aaaaaattgt tgcaaaacag tttgatttat gatagcagta gctcggcaga ggcacgtgtt
     5521 tatgctattg ataaagggca gggctatttt ctaaaaacag ccgctaaagg taggcttgcc
     5581 aaggaggccg ccctaactcg gtattgtcat agtaagggct tagcaacaga ggtgcttgat
     5641 tatatcagcg gtgatcagga ttggctttta accgcaaagg tagcaggaga ggacgccagt
     5701 catattgaat atttgtccga tcccaagcgc ttatgtcgta tcttagttga tcatatgcta
     5761 aagctgcata gcctgtcttt gtctgatttt cctgtagctg acaaaacgct agcctatatc
     5821 gaagctgctg aggctggtta tcaccaaggg cggttcaatc agtgcttttt accgcctcag
     5881 caacggtttc agtcccagga ggaggcttac aggcggattc aggagcttaa gctcttgtta
     5941 cagcatgaaa ctctgattca tggggatttt tgtttgccaa atatgatctt ggatcggtgg
     6001 caatttcagt ccatgattga ttggggggag gcaggaaaaa gcgatcgaca tattgatctt
     6061 ttttggctga tctggtcgct tcaattcaat ctaaaaacag atcggtataa agattatgtg
     6121 ctagattgtt acggccgaag gcatattgac ttagacatac tagatggtat cgcggcattt
     6181 gaagtatttg cttaggagga taagatgata aagcgtccta ttcatgtatc acatgaattt
     6241 ttaaaagagg ttttggataa gcagagtatt gctgttgatg ctactatggg aaatggctat
     6301 gacactgcct ttttagcaag tctgtcacaa agggtttatg cttttgatgt gcagcagcag
     6361 gcactgacca agacacaaga gcgcttggag cagcaaggct tgactaatgc agagcttatt
     6421 ttagctggac acgagcaggt ggatcaatat gttaaggagc ccattcgggc agccattttt
     6481 aatctgggct atttacctaa tgcagataag accttgatca caagacctga gacgactata
     6541 ttagccctag ctaaaatact tgatcggctt gagctaggtg gacggattgc tatcatggtg
     6601 tattatggtc atgatggcgg tagtagggag aaggaagcgc ttttggacta tattggtcag
     6661 ctcgatcagc gtcaagtaac agcaatgctc tatcagccaa tcaatcagat gaatcaaccg
     6721 ccatttttaa tcatgctgga aaaaatagca gctactgatt aggttttagc cagccttacc
     6781 tcaaggctta gactgtctgt gatttctcag gaaaaagaaa taaatcagca atctttggcg
     6841 acaattgtga tataatgaaa tagtatatta tgttttagga gttatattaa tggaagaccc
     6901 tgtgagtcag cctttattga ttcagttttt attgttagtc attctaacct tgttaaatgc
     6961 ctttttctca gccagtgaga tggctctggt atccttaaat cgctctcgtg tggagcaaaa
     7021 ggctgccgat ggggataaga ggtatgatcg cttgctgcgt gttttagagc agcccaataa
     7081 ctttttatcg accattcagg ttggtattac ctttattagc ctcttgtcag gggcgagcct
     7141 gtcagcctct ttagggcagg ttatttctgg ctggttaggt ggttctgcga ccgctcaaac
     7201 agctggcagc attatttctt tggtgttctt gacctatgtc tcgattgttt tgggagagtt
     7261 ataccccaag cggatagcta tgaatctaaa agacaagctt gctgtggttt ctgccccagt
     7321 gatcattatc ttggggaaat tggttagtcc ctttgtttgg ctcttatcgg cgtcgacaaa
     7381 tttgctgagc cggattaccc caatgacctt tgatgacgca gatgagcgca tgacgcgtga
     7441 tgagattgag tacatgctga ctaacagcga ggcaacgctt gatgccgaag agattgaaat
     7501 gctgcagggg attttctcgc ttgatgagat gatggcgcgt gaggtgatgg ttccaaggac
     7561 agatgccttc atgattgaca ttaacgatga tacgctagac aatatcaagg aaatcctaaa
     7621 gcagagcttc tctcgtattc cagtttatga tgttgacaag gacaaggtga tcggcttaat
     7681 tcataccaaa aggcttttag aatcaggctt tcgtcagggc tttgaaaaca tcagcatgag
     7741 aaagcttctg caggagccgc tctttgtacc agaaacgatt tttgtagatg acctgttgag
     7801 gcaattgcga aatactcaaa accagatggc tatcctactt gatgagtacg gaggggttgc
     7861 aggcttagtg acgcttgagg atttgctaga ggaaatcgtt ggtgagattg atgatgagac
     7921 agacaaggct gagcaatttg ttcatcacat tgatgataac acctatattg tcacagggac
     7981 aatgacgctc aacgacttta acgagtattt tgatacagaa ttagaaagtg atgatgtcga
     8041 taccatcgcg ggcttttatt tgacagggat tggtaccatt ccaagtcaga aggagaaaga
     8101 aagttttgcc tgtgatagca agcaaaagca tctggtcttg gtcaatgaca aagtaaagga
     8161 cggtcgtatc accaaattga aacttactat ttctaatata gaacagaata ttactgaaga
     8221 ctaggcattg agcttagtct ttttgatgaa acatgatata atgaaaacgt aaaaccgttt
     8281 acaagggtga aggagacaca atggttgaag tagattatgg gcaagtaact ggaatggtgc
     8341 attctacaga aagctttggt tctgttgatg gtccggggat acgttttatc atttttttgc
     8401 agggctgcaa gatgcgttgc cagtattgcc ataatccaga cacctgggct atggaaacca
     8461 atcaatctca acgccgaacc gttaatgatg tcctaaagga ggctctgcaa tataggcact
     8521 tttggggaaa aaagggtgga atcactgtgt caggtggtga ggctatgctg caaatggact
     8581 ttatcactgc gctctttact gaggccaaaa agctaggtat ccatacaacg ctagatacct
     8641 gtggctttgc ctatcgtcca acccctgaat accatgagct gttagaaaca ttattagcag
     8701 ttactgattt gattttgctg gatttaaagg agattgacga ggagcagcat aagcttgtca
     8761 cccgccagcc caataaaaat atccttcagt ttgctcgtta cctctctgat aggcaggtcc
     8821 ctgtctggat tcgccacgtc ttggtgcctg gcttgacaga cattgatgat cacttggtac
     8881 gcttagatgc gtttgtcaag accttgagaa atgtcgacaa gtttgaggtg ctcccttatc
     8941 atacgatggg agaattcaag tggcgtgagc taggtattcc ttaccagctt gagggcgtta
     9001 agccaccgac caaggagcgt gtggaaaatg ccaaaaagct gctacataca gaatcctata
     9061 ctgaatacat gaaccgtatt catcaatcat aggctaagct agagttggga aatgcccagc
     9121 tttttttgac tccatgtcaa ctgtagtggg tgactgataa ctaagcacga gacgaagctc
     9181 gttttctctt gtgtgatgtt caaagcgagg taaatgggtt ctataatttc catggtggat
     9241 ttacccacta cagaaattat agaaccgttt ttttgctgat gaagcgaagc ggctggcttg
     9301 atgagacctt cagcgttttt agacgagctc agacatgtgc taaaaagtaa tccttgaagc
     9361 attaaaccaa tcaaggacag tgtattgtcc ccaaatagct gaacagctca ttatagggac
     9421 tggcttgcct gttcttgtgt gtttgacagg actctttaat acctgaaatt ctgtaccctt
     9481 atgcccttta ggtccttgac ctgtgactgg ggaatctcct ttgattttag agcctatttc
     9541 tgctacaata agatgaataa agagaatgag gtagaaacat tatgtcaaaa ctattagttt
     9601 ttggtcatca aaatccagat actgatgcta tcgcatcatc gtatgccttt gactacttag
     9661 caaaaaaagc ctttgatttg gatacagagg tagtcgctct gggtgatcca aatgaagaaa
     9721 cagcctttgc ccttgactat tttggggtgt cagcgccaag agtggtgaca tcagcaaagg
     9781 cagaaggggt tgatcaggtg atccttacag accataacga atttccacaa tctatttcgg
     9841 atattcgtga ggttgaagtg tatggtattg tggaccacca tcgggtggct aattttgaga
     9901 cagcaaaccc gctttatatg cgtgtcgaac ccgttggctc tgcctcatct atcgtttacc
     9961 gtctgttcaa ggaaaatggg gttgatgttc caaaggatat tgcaggcctg ctcttatctg
    10021 gcttgatttc tgatacctta ctgttaaaat caccaacaac gcatgcttca gatcatcgtg
    10081 ttgctgtgga attagcggag ctagcaggag ttaagctaga ggaatatggt atggctatgc
    10141 tcaaggccgg aacaaacctt gcaagtaaat cagaagcaga attgattgat attgatgcaa
    10201 agacctttga attaaatggc aacgcagttc gtgtagccca ggtcaatacc gttgacattg
    10261 cagaggtgtt agagcgcaag gaggctattg aggccgctat tagagaggtg atggcaagtg
    10321 agggctattc tgattttgtc ttgatgatta cagatattgt taattcaaat tcagagattt
    10381 tggctcttgg tgcgaatatg gataaggttg aaacagcctt tgactttaag cttgaggata
    10441 atcatgcttt cctagcgggt gctgtatctc gtaaaaagca ggttgtccct caattaactg
    10501 aaagcttcgg agcatagagc ttgcctgtag aggactgttg atttttatca gcagtccttt
    10561 ggtctttttg ctataatagt agcatgatta ccatttttaa ccctgataaa ttaacgcgtc
    10621 agcctttttt tcaagacctt attcattacc tcaatcagca tgatgacgta accctgcgtc
    10681 acattaagca ggccttttct catgttaagg ggattgataa ggcgcttgaa gcttacattc
    10741 aggctggcta tatctgtcga aaaaacagac gctactatct gtgtctgccc ttgctagatg
    10801 acctgcagca ggtgacatta gaagatctaa tctttgtgga tagggcatca gatctatatg
    10861 aagctttgat ggccttggtg tttgagacag tgctgtctaa tcagaccaat caggttttga
    10921 tcaaggaaaa aacaaccatt gaccgagata agctgacgct tgccaattat ttttaccgct
    10981 taagaagagg ggaagcccta tctgatgagc aattaaggct ctatgcccta ttaggtgatg
    11041 tgaatcagga ctatgccttg aagtacatga ccagctttct tctaaaattt gctagaaaag
    11101 agattgttat gcaaaagcgg acagatattt ttgtgaatgc cttggagctt ctaggctata
    11161 ttgaaaaagt agaggccact aaatactgcc tgaagctggc ttttgataag gagcagctga
    11221 ttttctacgc tgattaagag ttgacttgat gaataaaaaa tggcttagac ccacactgta
    11281 aaacagttga gtctaagcca tttatgcttg ctgagccctt taagctatgc agcagaagct
    11341 cttatgtcat tttgaccatc agatagagaa aataggatgc accaataatt gagacaagaa
    11401 taccggttgg tatattgctg ccgacgagat agactcgtcc gatagtgtca gccaagagaa
    11461 gcagaatcat gccgatgaaa aggctgacag gcaggcttaa tcggtgatca gctcccacta
    11521 gtcgtttgct ggtatggcct gctatcagac caataaaggt gatgtttccg accaaaataa
    11581 cacttagggc tgagagaatc gcagatagtg caagaacaat ggtacggtac tgatggagct
    11641 tgaagcctag agccatgctt gcttcatcat ttaatgccat gatgttgagc ttataggctt
    11701 gactaaaggc tagcagccaa gtgatcccca ataagggagc aacaatgctt agcttggacc
    11761 aatcatcgcc tgttagctgc ccgcttagcc aatgaatcac ataatccacc ttataacggt
    11821 tcacattgcc gacaaaggca atcatcaggc tagatagcat ggttgatagc cctacgccag
    11881 tgacaatcag ccgaatagga tcaatatggc catgacgaag tgagagcagg tagaccaaga
    11941 taatggttgc cattgccccg gatatggtca taagcggcag cccttgcctg ctggtcagac
    12001 tgttactagt gctgtaggat atgacaaggg taatagccat accagcacca gcattaatgc
    12061 ctagtatgcc agaatctgcc agaggatttc gcgttaagct ttgcagcatt aagccagaaa
    12121 gggccagtga gccgccaccg atacaggcag ctaaaattct tggaagtcta atgttggtga
    12181 tgatcaaggc catatcagca gtggatttac caaaaagcac cctgacgacc tccaatggtg
    12241 acatgctaga ttccccaata gacaaggaaa taatcatcaa acagaccagt ccagagatta
    12301 gtcctagaaa taatgggacg tgtcttttag tagctgtcaa aagcgacctc cttttctaac
    12361 tagccataaa aagcagggca gcccaataaa gctgatcaaa gcagatagcg gtgtttcata
    12421 ggggggattg atattccgac aggcaaagtc tacccaaagc ataaagctgg ctccaagaag
    12481 agtagctagc ggcaggatcc agcggtaatc cttagcagtg actaatgtga tggcatgagg
    12541 gataatcaag ccgacaaagg aaatgctgcc ggctactgct acagcagcag aagacagaag
    12601 cagcacaagt ccaataaaga taaggctgat caagaaggtg cgttgcccta gggccttggc
    12661 ctgctcttga cttaagctta aaatggtcaa atgataggct agcagataag ataggactaa
    12721 gccacagatg atgagcggag caacatagct aaccatctgc caattgactc caatcaaacc
    12781 tcccgcctgc cagccgataa tggcattggc taggtgacaa taagttgtta ttccttgtcc
    12841 gatagctgat agcagcatag aaatcattgc tcctgctaaa atcagcctta tttgagtgta
    12901 gcccttgcga gtttgatagg ctagactaag aattaatagg gttgctaaga gtgaccctaa
    12961 caaggaaagc aagataattg tcgaataatg aaggtgaggg aaaaaagcat agccgataac
    13021 taatgccaga ccagcaccag agttgattcc cagtaagcca ggctcagcaa tgggatttct
    13081 cgtaatgccc tgcatgatag ctcctgaaac agcaagggca gcaccgacta aagccgctag
    13141 aatcaagcga ggcaggcgaa tatccaaaat aatgctggcc ttttgcccca gaccatgctt
    13201 tccaagcaga atatgaaaga gctcctgatg tgatagtgac acagaaccaa acctcagact
    13261 gcaataaatg gcaagcacta gggtcaagct gataaaggtt aaaatcagcc aaagaggggc
    13321 ttccttagtt agtttaggac tagtatgatg ttgagctgtc atcttaagct ttttagtgat
    13381 ttgcaccatt tgagagaata gcctttttca gaacctcaag ctggtgctct agtgacagtg
    13441 gatctgtgaa gtaaaagaca ttagcgttga ctttgatgac atgattgttg gtcacagcag
    13501 gaatctgctg ccaaaggtcg ctctcatata aggctgagcc ggtttggtca tcctcagcag
    13561 caacaaccac ataatcacca atataatctg gtagaacctc ctgtgataag gacagatagc
    13621 cctgcttaaa tacctctttt gtcacctttt caggagcatc ataatggaag gcctgatgaa
    13681 taatttcacc acctcttccc cagtccttac caaaaaggta aatttccttt tcatagagcc
    13741 ccataattgt aaaggtagca gctgatccgg tgactttttt cacttctttt tcatagtcac
    13801 ttgttttttg cttccagtcg gccaaccatt ggttggtttc cttttccttg ttaaagatac
    13861 gaccaaaatc agaaaatacc tgcaaataat cacgcttgcg gtattcaatg gaaattagcg
    13921 gtgcgatttt tgctagctgg tcaatgtttt cttctgttga gccaacaaca atgagatcgg
    13981 gctttagtgc tgtaatagcc tctaaatcag tagctgccac ctgcttggct tgagtaatgc
    14041 ttttcgttaa aacaggattc tttttgtcgt aggaggtgac accaactaga ttaaggtcta
    14101 attttgctaa gtaaccagta tatgtagctg ctaagctaac cacgcgcttt ggtttggcgg
    14161 gaatgtcacc ataataggtc actccggcga tttttggctt gtgggatagg cttgctttgc
    14221 tggtgttttc ttgtgacttg ttttggcttg agcaagcaac taatgtaact gctgtcacaa
    14281 aaacagttaa cataagcaat agttttttca tgtgttctat tctcctagaa taaatttata
    14341 tcagctgata ggtcagcaat gtagggcaat gatagagagg gtcagtgacg agctgagcct
    14401 ttatctgaaa aatgtcttgt atcatctctg gcgtcatcac ctgattaacc tctccagaat
    14461 atttgatatc tccatttttc atggcgatca gatgatctga gtagcgtgct gaaagattta
    14521 aatcatgaag gaccatcacg attgtttttc cagagacctg attgagctcc tttagtaatt
    14581 ctaaaatatc gagctgatga ttcatatcta agtaggttgt tggctcatct agaaaaataa
    14641 tatcagtatc ctgtgctaag gccatagcaa tccaggccct ttgacgttgg ccgcctgaca
    14701 gggcatcaac agcctgatga gcatagggtg ccatgcttgt gacctccatt gcccagcaaa
    14761 tcttatcctt atcagcttga ctgagccgtc ctaggtagga ttggtgggga taacgcccat
    14821 aagaaaccag ctcatagaca gtagctgtag tagcttcttg cagctgaggt aagactgcta
    14881 gtgttctggc aacgtccttg gttgctagtc tagcaatggc ttgtccatct aagagaacct
    14941 gccctgcttt gagtggcaat agtcgtgcca gagcctttaa aagggttgac ttcccacagc
    15001 cattagcacc gatgatggtt gttacctttc cttcgggaat agtgacagat aagttgctga
    15061 tgataagcga ttgatcatag ccagctgaaa tcctctcagc actgattgtt gacatggttt
    15121 ttctcctttc taatagtcaa gcaaagccag ctagcaaaat tctaaggggc tgatagccta
    15181 tgaaatgcta gtcgcttttt tggtctgact ataatagtgc gctttctctt aaaagctatc
    15241 ccattatagc atagaaaaaa ggcctaaaaa agcctttcag aatctaatta ctgagcttat
    15301 gctaaaaaag gagccagctt agaattatta tcagtaatct taagaatcat tactgtttag
    15361 cctgttagac cagtctatag gtagctcttt gcaatcgcta aatcacctgc ataggctgcc
    15421 ttttgtccct tgacgatctg ataagcatca gcccccttac cagcaataat gagtgcgtcc
    15481 tctttgctct gacagcgctc cataccagtc ttgattgctt ctttacggtc aatgataata
    15541 tcaacctcgc ggtgaatata gctagcaatc tcctctgaaa tcagctgtgg gtcctcaaaa
    15601 ttaggatcat cagcagtcag aataatatga acattggggt gctggttgat gacttgccca
    15661 aaatcagccc gacggctctc gcctttattg cccggtgctc ctagaatcaa gtagatctgg
    15721 cccttctggt actcctcaac gacagatagg agcttttcaa ggctatcacc gttatgtgca
    15781 taatccacaa caaccttggc ctgattggtc atggttaaga cctccatgcg gcctggcacc
    15841 cttgtcttag caattcctaa gcggatatcc tctaggcttg ctcctaatcg aagacaggcc
    15901 agtccagcag ccatagcatt ttcttggttg aagctaccaa tcaattgaat cgtatagtct
    15961 ccagataact tgccggctgc ttgaaatgaa aaggcctgac gctgcagcag cctgttacaa
    16021 gcccccttgc cataaaaatc atgaggctta tcggccacct gctctgctag gatatgaaag
    16081 tgctccatac cgctattgat gacaacagct cggctatttt ccattaaaag ccgcttatgg
    16141 taaaaataat cctcaaagct tgggtgttct attggtccga tatgatcagg gctaatattg
    16201 agaaagacac cgacatcaaa ggttaagccg tagacacgcc caaccaagta ggcttgacta
    16261 gagacctcca tgaccaaatg cgtcatgcca ttagccacac actgggccat cattgcaaat
    16321 aaatcaaggc tttcaggtgt ggttaattga gatttaaaaa agcttttgcc atctaaggtt
    16381 gtattcattg tagagagcag ggcaggctta tgagattcct ttagcatatg ataggcaaag
    16441 taggcagcag ttgtcttgcc ctttgttcca gtaaatgcca atagcttgag cttatgctgt
    16501 gggtaatcat agaaggccat cgcagctaga ctcatagcgt gcttaatatt gttaacaaga
    16561 ataacaggga tccctacctg atagtcaatc tctgaaacat agagtcttag tcccttggca
    16621 atggcctgtc tcaaaaagtc agctttaaaa gctgatccct tagcaaaaaa gagcgtctgc
    16681 tcatctgctt gtctgctgtc gtagctaagg ctgtcaaact gtagaccgct atagttaaag
    16741 tggtagccgt cttgatcaag aacctctcgg aaattatggt ccttttttaa aatggttaat
    16801 aagtgctcaa ttgtaatcat aaccttattt tagccttaat gttcttgttt tacaagtcac
    16861 aagcaaaagt ttataataaa gctataaaaa ctaggaagaa cagatatgtc gacagaaaaa
    16921 aaacaattga cacaagaaca gctgatggtt cagggggcgg cctggtccac cgctggtaat
    16981 tttattagcc ggcttttagg agttttatac attattccat ggtatatatg gatggggcag
    17041 tatgcgatac aggcaaatgc gctcttcaat atgggataca atgtgtatgc ctattttttg
    17101 ttgatttcga caacaggact aaacgttgcc attgctaagc aggtcgccaa gtacaactcg
    17161 atgggacagc aggagcatag ctatcagctc attcgaagca ctctaaaggt catgctggta
    17221 ttgggcttgg ttttctcagt gctgatgtat ctgggatctc cgctctttgc tcgcttgtcc
    17281 ggtggtgatg agacccttgt tccgattatg catagcttat cattagctgt ttttgttttt
    17341 ccagtgatga gcgtgattag ggggattttc cagggttata aggagattaa gccctatgct
    17401 cttagccaaa ttgctgagca gctggttcgt gtgatctgga tgcttctaac aacctttttc
    17461 atcatgaaaa tggggtctaa ggactatatt gcagctgtta cgcagtccac ctttgctgct
    17521 tttattggaa tgatagccag tatggcggtg ctcttttatt atttctggac gcagggcctt
    17581 ttaaaggcta tttttaccaa gacagagcat gcgattccta ttgacatcaa gggtctgctt
    17641 attgaaacgc taaaggagtc gattcccttt atcatcacag gaagtgcaat tcaggccttt
    17701 cagctcatcg accagtggac ctttgtcaat acaatgaccc tctttaccaa ttatactcgt
    17761 tctcagctct gggtgctgtt tggttatttt aatgccaacc ctgctaaaat caccatggtc
    17821 ctcattgcag tagccgcttc aatcggtagt gttggtattg ccttattgac agaaaattat
    17881 gttaaaaagg acatgcgagc agcagcgcgc ctgatcatta acaacattga aatgctgctg
    17941 atgtttttat tgcctgctct gacaggagct attatactgg caaggcctct ttatacggtt
    18001 ttttacggta gtagcgagga acaggctgtt aggctgtttg ttgctgtgct ttgccttacc
    18061 ctattgatgg ccttgtatac gcttttttct ccgatgctac aggccctgtt tgaaaaccgt
    18121 aaggccatct attattttgc ttatggtgtt tttgtcaagc tggttttgca ggttccgttg
    18181 atctatctgt ttcatgctta tgggccttta ctggctacga cctttggctt actagtgcct
    18241 atttatctca tgtatcgtcg tttgcaccag gtgacacgat ttaatcgacg cttgctgcat
    18301 aagcgtatcc tattgacggt gattgagacc gcgctgatgg ggctgattgt gctgctgtca
    18361 agctggcttt tgggctatgt gatcaagccg acaggcagat tgactagcct gctttactta
    18421 gtgattattg gtggcttagg aatgggtgtt tatgcctaca tgacgctagt aacgcgtcag
    18481 ctggacaaat taattggcag tagagcagct aggtatcgcc aaaaattggg gctttgacac
    18541 ccaagatcaa ggtagctgac gcaggccgct agctgataat atccttactc ttagcatctc
    18601 aacatgatct gaaaaaagta agcaaggttt tcaatttttt ggtataatag caaaagtgta
    18661 aaaaataaag aaggaagtac gtcatcatgg gaaaatgtca ggttatttcg catccactta
    18721 ttcagcataa gctgtcaatc ctgcgccgtc aggatacctc aaccaaggat tttagagagc
    18781 tggtcaatga aattgcaatg cttatgggct acgaggtgtc tcgtgacttg ccattagagg
    18841 atgttgagat tcaaacaccg gttgccaaga cggttcaaaa gcagttagca ggtaaaaaat
    18901 tagcaattgt tccgattctt agagctggta ttggtatggt ggatggcttt cttagccttg
    18961 tgccagctgc caaggttggt cacatcggta tgtatcgtaa cgaggagacc ttggagccgg
    19021 ttgaatattt ggtgaagctg ccagaggata ttgatcagcg ccaaattttt attgttgatc
    19081 caatgcttgc tactggcggc tctgctattc ttgcagtgga ttcactgaaa aagcgtgggg
    19141 ctgctaatat taagtttgtg tgtctggtag cagcaccaga aggggttaaa aagcttcagg
    19201 aggcccaccc agatgttgac atttatacag cagcccttga tgaaagatta aatgatcatg
    19261 gttacattgt tcctggtctt ggagatgctg gtgatcgctt gtttggtacc aagtaaaagg
    19321 ctacaggctt tggttgtgct aggctctgct tgctagaggc tagcctgcta aagctgataa
    19381 gactttctag tttaggctgg aaggttttta aaagcaagtt tatcatttga ccttttttga
    19441 ccaagagatt ataataaggt caatcattat aaaaagatgt gtttgactga ttgtcactgc
    19501 atgaggctga gtggcgttag acagtcacga tagattggag atttttatga ttcctgtagt
    19561 tattgaacaa accagtcgtg gagagcgttc ttatgacatt tattcacgtc tgttaaagga
    19621 ccgtattatc atgctgactg gtccagtaga ggataatatg gcaaactctg ttattgcgca
    19681 gctcttgttt ttagatgccc aagacaacac aaaagacatt tatctctatg tgaatacccc
    19741 aggaggctct gtatcagctg gtctagctat tgtggatacg atgaacttta ttaaggcaga
    19801 tgtgcaaacc attgttatgg gtatggctgc ctctatggga accgttattg cttcatcagg
    19861 tgcaaagggc aagcgcttta tgcttccaaa tgcagagtac atgattcacc agcctatggg
    19921 aggcacaggt ggcggtacac agcagacaga tatggccatt gcggctgagc atttattaaa
    19981 gacacgtcac cgcttggaaa agattttggc acaaaatgcc ggtaaaacga tcaaacaaat
    20041 ccataaggat gctgagcgtg attactggat gagcgcagaa gaaaccctag cctatggctt
    20101 tattgatgaa atcatggaaa ataatgagct agcttagtca ataacttaac agcttctgaa
    20161 acaaattgtt tcaggggctt tttgcatgtt aaagagggct atcttcctta aaattatggt
    20221 ataattaacc tatgctaatc ataaatgaag aattgtttgc cattgaaaag gctatcttgc
    20281 agctggttca ggatattagg acaagcagcc agtatcaggc ctatgccttg gctaaaaagg
    20341 cttttgaggc agatttggcc ctacagaccg agttagcctt atttgaggag cttaagcagg
    20401 attatgagct taggcaggac ttgcttaagt cgtgtccaga tgctagagcg ttgcgttgcc
    20461 aattacttca tcaaaagcgc cagcttgacc tgcatccatt ggttgctgat ctgcgcttgg
    20521 cacaggttga tttgcaggag gttttggcga cgatttcgac agctattgca gaagcagtgt
    20581 ctgaggatat tcttgtcgac acagggcttc ccttggcgac aaatagacct cgacatgagc
    20641 ttggaccgta tcaaaatata aaagaaaaga gtacctaaat gtttcaaaaa cagcagagaa
    20701 ttgggctggt tatctacctg tattacaatc gagacgctag aaaagtgatg aaatatggtg
    20761 acttgtacta ccattccagg cgttctcgat accttgttat ttacatcaat aaagaggaca
    20821 tggaagaaaa gctaaaggac attagtcggc taacatttgt caaagaggtg aaggtatcag
    20881 cctttgatga cattgattgt gattttgttg ggaatttaca tcgtgagcct ctagagcctc
    20941 aagccctacc tgagcagggc taagtaggcc tgatcctgtc ttatatagca tgtcttagct
    21001 catcaattgc tcaaagctga tggatcagcc ctgctggctt gcttaggcaa agaaaataag
    21061 agctgagacg attgtcattt atcgagtggc tgctcatagg ctttgaggtg tgaggcacag
    21121 gccttagact gctgctttga gggctggctt tttattccta tcgcctaaaa ggcagcacaa
    21181 aaaggctttt ttctgatctg gcactgccca atgaattggc agtgcttttt caggcaaatt
    21241 ttggtaaaat agaggtaacg ataaacaaag gaataaagat gactagagga aaattaataa
    21301 cgtttgaagg tccagacgga gcaggaaaaa caacggtgct ggaaagactg gtgccactct
    21361 tacaggcagc tctaggacaa accattgtaa caacgagaga gcctggaggt gttgcgattg
    21421 ctgagaagat tcgtcagctg atcttagatg tcagtcacac gaccatggac gataaaacag
    21481 agctgctgct ctatattgca gcaagaaggc agcatttggt tgaaaagatc atgccagctc
    21541 ttgagtcagg acacttggtt ttggtggatc gttttattga cagttcagtt gcttatcaag
    21601 gcgccggaag agggctggat aagcaagcca ttcaatggct caatcatttt gcaacagatg
    21661 gtgttgaccc tgatttaacc ctgtattttg atgtgccctc agagcttgga ttggcaagga
    21721 ttgcacaaaa tactgagcga gagatcaatc gtcttgatct tgagcaatta gatttgcacc
    21781 agcgtgttcg taagggctat ctggagctgg ctttggaaaa tccccagcgt attgtcaaga
    21841 ttgatgcatc acaggactta gaaagcgttg tgtcagcggc tttagctgcc attatcacac
    21901 acagtcaagc atagcaggag gttaggaatg gatttggctc aaaaggctcc tagggtctat
    21961 caggcctttc aagagatttt gcaaaaaaaa cgtctaaatc atgcctacct cttttcaggt
    22021 gattttgcca attttgacat ggctcttttt ttagctaaga ctcttttttg tgaacaaaaa
    22081 agaggcaatg ccccttgtca tcactgtcgt acttgccagc tgattgagca caatgacttt
    22141 tctgatgtca ccatcttaga gcctgtcggt cagctcatca agacagatac cgtcaaggaa
    22201 atgatgacga acttttcaca gaccggctat gaaggtaagc gacaggtttt tatcattaag
    22261 gattgtgaca agatgcatgt caatgcagct aacagcattt taaaatatat agaagagcca
    22321 caaggtgatt gctatatgtt tttactaaca aatgatgaca accgagtcct accaacgatc
    22381 aagagccgta cacaggtttt tcacttccca aaagatgagc actatctctc tgagctggct
    22441 caaaaaaagg gacttttgaa acatcaagca gacctcttag ccagattagc agttaatgcc
    22501 cagcagctca ctgttttttc tgaaaacacc agattgttag agctgatgac gcaggctgag
    22561 cgttttgttt ccatctggtt tcaagataag gaacaggctt atttggaact taaccgcttg
    22621 gttcagctag cagaagaaaa agaggagcag gacatggtac tgactctttt aaccttaatc
    22681 ttggcaaagg actaccatcg acaaaatgct tttacctatc tggaggctgt ttaccaggct
    22741 agactcatgt ggcaaagcaa tgtcagcttt caaaatacgt tagaatatat ggtgatttca
    22801 tgataagtac gattggaatt aaatattgtg acacctgctc tgtcaggtac gttcaaaccg
    22861 atcaggcctt tcctgtgcaa accaagcttg tcatatctga tggcaagggc agtcgcttgg
    22921 cagtggtcaa ttctccgata aaaagctttt gtaaggacga cctgccaaag gatatgccct
    22981 ctgttttgag acctgccaat gacatggatc acaaggctta ccagcaaaac cttcagctag
    23041 cagcccagtc aaagcaaaaa gtagcagaga tgattgacag aaatggctta gacatgacct
    23101 tggttgacat tgttttctcc cttgagagac gttatgtttt gattactttt accgctcagg
    23161 agcgtgttga ttttcgccag ctcctcaaag atttggctgc ctacttcaag acaaggattg
    23221 agctgcgtca gattaatagt cgtgaagagg caagggttta tggagggctg ggtccctgtg
    23281 gtcgcccact atgctgttca agctttttag gagagtttcc tccagtctca atcaaaatgc
    23341 taaaacatca agggctgtcc ttgcattcgg caaagtcttt gggctgctgc ggtcgcttgc
    23401 tgtgctgcct acaatatgag gacgattttt atcaagaaag taagaaaaaa tttcctgatt
    23461 atggtactat agtaagaaca gcgcagggac caggtgaggt tgcaggaatt gatcttttta
    23521 cagataccat tcaggttcgt tttaaggacc agctggcctt ggtaacctat gctttagagg
    23581 aggttaaagt tagtgaataa aaaagaactg tttgacgctt ttgatggctt ttcacaaaac
    23641 ctgatggtga ctttagctga catcgaagca atgaaaaagc aggtccaagg actggtagag
    23701 gaaaatacta tccttaggct tgaaaatacc aaattacgtg agcgcttgag tcaattggag
    23761 cacgaaaatc tggcaaagac ctcttctaag cagggcaagg accacttgga gggtatttat
    23821 gacgagggct ttcatatctg caattttttc tatgggcaac gtcgtgaaaa tgatgaagag
    23881 tgtatgtttt gtcgagagct attagataga aagtagagtc atgcaaatcc aaaagagctt
    23941 caaggaagaa aaagaatcag gggttctcta tctggtgcct acccctattg gtaacctaga
    24001 ggatatgact tttagagcag tcaatgttct aaaagaggtg gatattatct gtgcagagga
    24061 tacgagaaac actggtttgt tgctcaagca ttttgggata aagacaaagc aagtaagctt
    24121 tcatgagcat aatgcttatg ataaaattcc agatttgctg gaccttttgt tggctggaag
    24181 gtcattggct caggtctctg atgctggtat gccctctatt tcagatcctg gtcatgagct
    24241 agtcagagca gctattgatc gagacattac tgttgttgcg ttgccgggtg cttctgcggg
    24301 cattactggt ctcattgcta gtggcttggc gccccagccc catctgtttt atggcttttt
    24361 gccaagaaaa gcagggcagc aaagggcatt tttgatgact aaggcagatt atccagagac
    24421 tcaaatcttt tatgaatctc cttatcgtgt taaggatacg ctaacaaacc tgctgacctg
    24481 ctatggggac cgtcaggtgg tgctggtgag agagctaacc aagctttttg aggaatacca
    24541 gcgtggtcag atttcagagg tcttgaccta tctagcagac catccaatca agggtgagtg
    24601 tctcttgatt gtggcaggtg ccaatcaagc tgacgcatca gagtctgctg aggatttgga
    24661 tctgctagca cttgttcaac aggctatcgc tgctggcatg aagcctaatc aggcgatcaa
    24721 gacaatcgcc aaagactata aggtgaatcg ccaagagctc tatcagcaat ttcatgggct
    24781 tggctaggct ggttttaacc tagaccagtc acttgactga gagaatctct aataggctaa
    24841 gcaaaggaga ggtactcaag caagggctag tagctgtctt ttgtacttct gagaattgtc
    24901 attaatgtag gcagatagat ttgtcggcac actaagagag ctagttagtt ctcttttttg
    24961 ctttttgtca actgtagtgg gttgactgac aactcgcacc tagtgaggac cagactggtg
    25021 ctttcttttg tgctgttaat agcaatgaga agcttgcttt taacattttt aaggtttcta
    25081 aagccgcagg cttgtcgctt cacaccttcc cttaatggtc actttgcagt cttaaacgaa
    25141 aaaatgctcc catttaggac gtttcaacga ctgtttagga tatggaggaa tgttttacaa
    25201 aaaaagcgtt atactaaata tgtcaaggtt gcaactggac aacatcaatt tttagggagt
    25261 atttgcaatc aatacaataa tttgacgtaa tggctacaga aatgcttgct agctttgaag
    25321 gaggaaaaaa taattgggct gccaatgtgt caggtgtgat tggagcagga agtgcaggcg
    25381 caacacttgg atttccagta tgtggagtgg cttgtggatc tattggtgca aaaactgggg
    25441 ttacactctg ggcttgggct actggtgtca caggaggctt ttagaactta gaaaaacaga
    25501 aagattctga gtttagaatt ttgttttagg aggataatag aatggaacat tatagagcat
    25561 tagcaataag tgaaatgcaa gatatttcag gaggaaatgc agcaggtaat gctgttatcg
    25621 ggggattagg aggtctcaag acaggaatta cattttgcaa aatacctcat ccggtgctaa
    25681 aaggagtatg tatagacggc tttactgctt taggagcatg cttggcatat aaggtaaatt
    25741 agatgttatt gattactttt tcaggtcttt atgctttaat ttttatctat atactggttg
    25801 acagtgctaa gaggggcaaa gaagggtctt cctactttat ttttttaatt ttttatttct
    25861 tatcgactac tataagcaat gtaaatctta tatcccttgt gaccttacta tgttttttag
    25921 ctatttatat agaaaaaagg taaattaagt tttgtatggt tcgtttagat actttttcaa
    25981 cagtttaggg agtatttgta atcaatcaga aatgctgata aatgctgaag gtcggctatg
    26041 gataggcact ggaggtgtaa gaaacatcga tgctggtact taaaagtagc ttggtgtcag
    26101 atagtgagtg gcagtgaggg ttcataccaa aatggtcatt aaatagtgat tgatagctgg
    26161 tgaaggcaat aaataagatc aacatcattc ctttcactct atcaataatt gcctttttta
    26221 ttcggctggg tgatctattc ttggttgagg gatagcaaag tccttacctt taccttatgg
    26281 gctctttggg ggttatcata taagggagta agcctggtta agagagtttt agcgctttaa
    26341 aattgtaaaa tcagattatt taatgtatac tagaggaaat aagatgaata aagacggaag
    26401 gtcaatacaa tgataatcaa aaaactttca gtaatagctc ttacgagtct atccttaatc
    26461 agcctatcag cttgtcgtca acagaatcag gctctaggtc aaaatggcag cgctcagaat
    26521 cataggaagg caagtgtttc agaggacaag gccaaggagc ttgcctttaa ggacgcctca
    26581 atcacagcag ctgacgctca aaggctcaag ctgacgaaag aaacagacga tggtagagtg
    26641 gtctatgata ttgagtttga cgccaaggac caagagtaca gctataccat tgacgctaat
    26701 accggtgaga tcctagaaaa atcctctgag ccaatcactg agactcacgc agctggtggt
    26761 caggctgata aagcagctgg catttcagag gacaaggcca aggagcttgc ttttaaggac
    26821 gcctcaatca cagcagctga cgctcaaagg ctcaagctga cgaaagaaac agacgacggc
    26881 agggtggtct acgatattga gtttgacgcc aaggatcagg agtacagcta tactattgac
    26941 gctaatagtg gagagatttt agaaaagtct tctgagcctg tttacgatta agaagctatc
    27001 accgtttacg tgatgaaagc ctgtaacact cctaagccct taaatgctaa agggcttagg
    27061 ttttttgttg ctccttgtta gctgataaag ctggagcttg ttggcagcca tttaggcgct
    27121 tagtctatag cccgcctttg ttgctggtat ttggctgtga taagggctgt ttagttgaaa
    27181 tgataggcat tatcagctta ggacttggta gagtgatact tttatgacta gaaggatagg
    27241 ctatgggctg taaatgttgt ataatagagt agaaagcgct tgctatgatt gagagggctt
    27301 atctcagcag cgatagaatg gaggacacat gggaactgaa acctatatta tggctattga
    27361 tcagggcaca acgagctctc gtgccattat tttcaacaag aaaggagaag cgctggttag
    27421 tagtcaaaag gaatttccac agctttttcc acaggctggc tgggttgagc ataacgccaa
    27481 tcacatttgg aattcggtgc agtctgttat tgcagacgcc tttatcgagt ctggtataaa
    27541 gccagagcaa atagaagcta taggcattac caaccagcgt gaaacaacgg tagtctggga
    27601 caaacagaca ggtctgccca tctataatgc tattgtgtgg cagtctagac aaacagcctc
    27661 cattgcagag cagctcaagc gtgacggcta taccaaaatg atccatgaaa aaacaggtct
    27721 ggttatcgat gcttattttt ctgcgaccaa gcttagatgg cttcttgatc atgttccggg
    27781 ggctcaagag cgagctgaaa ggggagaatt attatttggc acgattgaca cctggctggt
    27841 ttggaagcta acggacgggg cggtacatgt gacggattat tctaatgcag cacgtaccat
    27901 gctatacaat atcaaagagc taaaatggga cgatgagata ttggccttgc tgaatatccc
    27961 taaggccatg cttcctgagg tcaggtctaa ttcggaaatt tatggtaaaa cggcttcttt
    28021 tcatttttac ggaggagagg tagctattgc tggcatggca ggtgatcagc aggcagccct
    28081 atttgggcag ctggcctttg agcctggtat ggtaaaaaat acctatggca caggctcttt
    28141 tatcatcatg aacactggtc aagaggctca attatccagc agcaatttgc taacaacgat
    28201 tgggtatggt attaatggca aggtttatta tgccttagaa gggtctatct ttattgccgg
    28261 ctctgctgtg caatggctgc gagatggttt gcgaatgata aaaacctctt ttgagtctga
    28321 acagcttgcc ttggcttcaa ccaatgctga tgaggtgtat gttgtaccag cctttacagg
    28381 tcttggcgct ccttattggg attccaatgc acgcggctcg gtatttggct taacgcgtgg
    28441 aacaacaaga gaggatttta ttaaggctac cctacagtct attgcttatc aggtcagaga
    28501 tgtgattgat accatgcagg tggattcagg gatcacaatc cagcaattac gtgttgatgg
    28561 tggagcggcc atgaataaca tgctcatgca gtttcaggca gatattttag ggattgatat
    28621 tgctcgtgct gaaaatcttg aaaccacagc tctaggagca gcctttttgg ccgggcttgc
    28681 tgtaggctac tgggaggaca tggagacgct aaagcaatta aatgccacag gtcagctatt
    28741 taaagcaagc atgagtgact cccgccgaga aaagctatat caaggctgga aaagagctgt
    28801 caaagccaca cagtttttca cagaggagct gtaagaatca ggccttttaa agaaacagag
    28861 tcccctagct aggtctagtt ttgaacacta gactgtgtga tacttggtct tttatatcct
    28921 aggagtgact tttataatga tagtgtagac ggtaaacagc gtcgtgctgt tcaatgactg
    28981 ataacagact aattaacgga ggttaagatg aaatttttct tagacacagc aaatgtagag
    29041 gcaattcgtg cgattaatga gcttggtgtt gtggacggtg ttaccacaaa ccctagcatt
    29101 atctcgcgtg agggtcgtga ttttgagaca gttatcaagg aaatctgtga gattgtggac
    29161 ggccctatca gtgcagaggt caccggacta accgcagagg aaatgattgc agaggctagg
    29221 aacattgcca agtggcatga caatgtggtc gtgaaaattc cgatgacgac agagggctta
    29281 aaagcaacta atgtcttgtc acaagaaggc atcaaaacaa atgtgacgct tatttttaca
    29341 gttagtcagg gactaatggc gatgaaggct ggtgcgacct atatcagtcc atttatcggg
    29401 cgcttagagg atattggtgc agacccttat cagcttatta gtgatttgcg tgggatcatt
    29461 gatttgtatg gcttccaagc agaaatcatc gcagccagca ttcggacagc tgcccatgtt
    29521 gaagctgttg cacagctagg ggcacacatt gcaaccattc cagatccatt atttgcgaag
    29581 atgactgagc acccattgac aacaaatggc ttaaagacct ttatggagga ttgggcttcc
    29641 tttaaaaaat aggctaagag catagagctc tccttatatt ctaatgtggc tgtagcggtt
    29701 agtttgggat tagctatttg taggtggcag gatcagctgg tgctttgctg ttgcgctaga
    29761 attaacaggc agctggcgct tactgtagcc aaagggaggt accaaagagg aatgcttgct
    29821 tagctggcaa cagctaggct tgctttttct tatgagcata ggtgctctat ctaagacagc
    29881 tgtcaatcac aaaaagctag gaacagcaat gcttattgct agataagaat ttaaggactt
    29941 tataggattt tgttaaaaat cagtttactt ttatgttaca atagacaatg gaaaacgttt
    30001 aatttttagt tgtaatacac agagaggttt tacttatgac atttgatgca attgatcagc
    30061 tggcagttaa tactgttcgt actctatcaa tggacgctat tcaagcagca aattctgggc
    30121 acccaggttt gccgatggga gcagcgccga tggcttatgt gctatggaac catgttatga
    30181 cggtcaatcc aaagacaagt cgtcgttggt caaatagaga ccgctttatc ctatcagcag
    30241 gtcatggtag tgccatgctt tacagcctat tgcacctagc aggctatgat gtgtctgttg
    30301 aggatctgaa gaacttccgt caatggggct ctaaaacacc aggtcaccca gaggtcaatc
    30361 atacagatgg tgttgaggca accacaggac ctttaggaca aggaattgcc aatgcagttg
    30421 gtatggctat ggcagaagca cacttagcag ctaagttcaa taagcctggc tttgatattg
    30481 tagaccacta tacctatgct ctaaatggtg acggagacct tatggagggt gtcagtcagg
    30541 aggcagccag tctggccggt cacttgaagc ttggtaagct tgtcttgcta tatgattcaa
    30601 acgatatttc gcttgatgga ccaacctcaa tggccttcac agaagatgtc aagggacgtt
    30661 ttgaagctta cggctggcag catatcctcg ttaaggatgg taacgaccta gaagctattg
    30721 ctaaagctat cgaggaagct aaggcagaga ctgaaaagcc aaccattatt gaagtaaaga
    30781 caatcattgg ctttggtgct gaaaagcaag ggacttcagc tgttcatggg gctccgcttg
    30841 gtgcagaagg cattgccttt gctaagaaat cttatcaatg gacccatgct gattttgagg
    30901 tgccgcaaga ggtgactgag cgctttagac aaggccttca ggcgcgtggt gagcaggctg
    30961 agcaggcatg gaatgaccta tttgcagctt atgaagcagc ataccctgag ttagcagccg
    31021 aatacaaaaa agcctttgct aatgaggcgg cagaggttga gttgcaagct cacgagcttg
    31081 gcacagcagt agccagtcgt gtttctagcc agcaggctat ccaacaaatc tctgagcagg
    31141 tgccagcctt ctggggaggc tcagctgacc tttctgcctc taacaatacc atggttaagg
    31201 ctgagacaga cttccagccg ggtcattatg ctggtcgtaa catctggttt ggcgtacgcg
    31261 aatttgcaat ggcagcagcg atgaacggta ttgcccttca tggtggaaca cgtgtttatg
    31321 gcggaacctt ctttgtcttt tcaaactacc tattgccagc ggttcgtatg gcagccttgc
    31381 agcagctacc aacggtttat gtcatgacgc atgattctat cgcggttggt gaagatggtc
    31441 cgacccatga gccaatcgag cagctagcta gtgttcgatc aatgccaaat ctgaacgtta
    31501 ttcgtccagc tgacggcaat gaaacaaacg ctgcttggaa gcgtgcgatc gctgagacag
    31561 accgtccgac aatgcttgtc ttaacacgtc aaaaccttcc tgtacttgaa ggtactaagg
    31621 aattggcaga agatggcctt aataagggag cttatatcct gtcagaggca aagggtgacc
    31681 ttgatgggat tatcattgca accggctctg aagtcaagct agcaatggat actcaagccg
    31741 ctcttgcagc agatggtatc catgtgcgtg tggtatcaat gccatcacaa aatatctttg
    31801 atgagcagcc agcttcctac aaggaggaaa tcctaccagc agcagtgaca aaacgtctag
    31861 ctattgaagc aggctcaagc tttggctggg caaaatacgt tggccttgca gggaaaacac
    31921 tgaccattga tacatgggga gcttctgcac cgggcaatcg tatctttgaa gaatatggct
    31981 ttacagtaga gcatgctact gaattgtaca aatccttatc ataagtgatt aaggtggagc
    32041 aggccttatc taggcttgct ttcggcatta ttagacaaaa aaacgcatga tgttcaaccc
    32101 tttttaggga ggacgtcatg cgtttttgtt tcagatttaa tagtgctact gctcagcctt
    32161 gcagatctat cctgagttgc tagaagctat tgtcaaatag ctggcttagc ttttctttct
    32221 ttttagggtt agcagacctg cgctagcgat gacgctaaga gctgccagac taaagaatgg
    32281 atggcttgcc tctcctgtag ctggtaggac tgcttttttg cttgttgggg ccactgattt
    32341 gcttagtgtt gactgaggtg ctggtgcctt agggctagct gactgctctg aagcctttgg
    32401 agctttcggt gcaggagcct tttcaggagc ctgtggcttc tctggcattt ttggtgattc
    32461 tggtgccttt ggaactgatg gcttggtatc ctttccttgg tcaccctttg gctgttgctc
    32521 accattttca ccgcgttgac cttggtcgcc tttttcgcca cgttgacctt ggtcgccttt
    32581 ttcgccacgt tgaccttggt cgcctttttc accgcgttga ccttggtcgc ctttttcgcc
    32641 acgttgacct tggtcgcctt tttcaccgcg ctgaccttgc tcgccttttt cgccacgttg
    32701 accttgctcg cctttttcgc cgcgttgacc ttgctcacct ttttcgccac gaagaccttg
    32761 ctcgcccttt tcgccgcgtt gaccttggtc gcctttttca ccgcgttggc cttgctcacc
    32821 tttttcgcca cgaagacctt gctcgccctt ttcgccgcgt tgaccttggt cgcctttttc
    32881 gccgcgaaga ccttgctcgc ctttttcgcc gcgaagacct tgctcgccct tttcgctgcg
    32941 ttctcccttg tcacctttag gtccgcgttc cccttgttta ccagcaggtc cagtctcacc
    33001 ttttggacca atagggcctt gctcaccggg tgcaccgttt tcacccttgt ctccgcgcgg
    33061 tccctgaggt ccggtttccc ctttttgccc cgctggacct gccggccctt gaggtccgac
    33121 aggtccaggt tttccttgct gtccctcggg cccacgtgct ccatctaagc cttttggtcc
    33181 tgctggtcca gcaggacctt gaggtccccg ttctccccta ggcccagcgg gtcctggttt
    33241 ggttaattca aaatttattt ctccaaggta atttttaaaa tattcttcca gttcacttaa
    33301 atatttccta atcgaacctg tagtatagac attgctaata ccattttgta tttgaagagt
    33361 tttgtcaact ttaggaaatt gacttaatag ttgttgaagt tgtgatgcct ctcgctcctc
    33421 cgcgtgagca gttgctccaa tccttgctga tgctatgaga acaatcgctg ccgagcagac
    33481 accatacctg tagataagtt ttttctttct tttattta
//
LOCUS       DARYSY010000023        31295 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYSY010000023 DARYSY010000000
VERSION     DARYSY010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31295
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            71..1189
                     /locus_tag="TVR04_000961"
     CDS             71..1189
                     /locus_tag="TVR04_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEL1269662.1"
                     /translation="MMDNIINFLITVKDDREPWKIKHVLSDIVLLIFFARLSGAEYWD
                     EIEAFGQAYEATLKTVLQLENGIPSHDTLQRVFATLDPQVLVEVTQMWSDILEESDLS
                     SRNLFSFSKRLVAIDGKTIRGNGSAKQKALHIVTAYATDLGISYGQVATNEKSNEITA
                     IPELLDMISVKGCMVSIDAMGTQKAIADKIIKKKADYCLAVKENQKTLLEDIVPFFEM
                     SQEADDHYHTVEKAHGQIETRAYEVIHDVSWLRKTHPEFGHIQSIGRARIHLDKNGQE
                     SEESRYFILSCQVSAKELCDYVRGHWQIESMHWLLDVVFREDANKTLNKQLAFNLNVM
                     DKFCLAVLKRLDFGKKMSMRRKKYALSLSFDKYLKKIT"
     gene            1338..3839
                     /locus_tag="TVR04_000962"
     CDS             1338..3839
                     /locus_tag="TVR04_000962"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1269663.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAVFTA
                     ENIANFKRQINALGFSYDWDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSGFLDGLDKAAA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDKQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVIKVIAVPNKLVNIVVK"
     gene            4026..4496
                     /locus_tag="TVR04_000963"
     CDS             4026..4496
                     /locus_tag="TVR04_000963"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269664.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSYNNWNLTPEQRAKKLR
                     ELKLSRSKRSLVLSELERKRKSMVENLTTGFSDLTVSEKREFITLVKRAYSSEEIDRI
                     HKEAVEKVIAKTNLYHQYAQLLRKGYKDDVEIDQSKLPLYEYQNLKEIIRHLKK"
     gene            4901..6334
                     /locus_tag="TVR04_000964"
     CDS             4901..6334
                     /locus_tag="TVR04_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1269665.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPSFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGTGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            6450..6728
                     /locus_tag="TVR04_000965"
     CDS             6450..6728
                     /locus_tag="TVR04_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1269666.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            6946..7431
                     /locus_tag="TVR04_000966"
     CDS             6946..7431
                     /locus_tag="TVR04_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1269667.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLSQPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLIACRTPEEVLALVDESKNSPYLEGLDLD
                     S"
     gene            7526..8191
                     /locus_tag="TVR04_000967"
     CDS             7526..8191
                     /locus_tag="TVR04_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1269668.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGDRGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            8196..9059
                     /locus_tag="TVR04_000968"
     CDS             8196..9059
                     /locus_tag="TVR04_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1269669.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKALGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEELFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLR"
     gene            9060..9776
                     /locus_tag="TVR04_000969"
     CDS             9060..9776
                     /locus_tag="TVR04_000969"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1269670.1"
                     /translation="MAKDLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELERIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            10079..11725
                     /locus_tag="TVR04_000970"
     CDS             10079..11725
                     /locus_tag="TVR04_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1269671.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVTDYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKSDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMVAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADQEKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPILIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            11920..13011
                     /gene="ulaG"
                     /locus_tag="TVR04_000971"
     CDS             11920..13011
                     /gene="ulaG"
                     /locus_tag="TVR04_000971"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1269672.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEESNIQFKALL"
     gene            13076..13318
                     /locus_tag="TVR04_000972"
     CDS             13076..13318
                     /locus_tag="TVR04_000972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269673.1"
                     /translation="MTSSYGQSKLTLYLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            13517..14713
                     /locus_tag="TVR04_000973"
     CDS             13517..14713
                     /locus_tag="TVR04_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1269674.1"
                     /translation="MGTILEVKHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKMSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            14731..16461
                     /locus_tag="TVR04_000974"
     CDS             14731..16461
                     /locus_tag="TVR04_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1269675.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISILLGIPLGIWMAKNKTVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMSSSSSDKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQRA
                     YSNLTDWELIAASTGAMTTSLDQAIKKKEPIVVTAWSPHWIFAKYDLKYLADPKKTFG
                     SKENINTIARKGLKADLPAVYRIVDHFYWTQEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            16858..19500
                     /gene="polA"
                     /locus_tag="TVR04_000975"
     CDS             16858..19500
                     /gene="polA"
                     /locus_tag="TVR04_000975"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1269676.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTELPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYQHVDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTELFKKVLEQPIATYDFKRSKVLLSHLGLDLLA
                     ASYDARLANYLLSTVEDNEMATLARLYTTIPLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKELVKETM
                     ESAVNLAVPLRVDESAGKSWYEAK"
     gene            19741..20193
                     /locus_tag="TVR04_000976"
     CDS             19741..20193
                     /locus_tag="TVR04_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1269677.1"
                     /translation="MIDTFQNPSDETIVSYLESAKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFEVDIVNVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            20230..20703
                     /gene="perR"
                     /locus_tag="TVR04_000977"
     CDS             20230..20703
                     /gene="perR"
                     /locus_tag="TVR04_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1269678.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY"
     gene            21064..22818
                     /locus_tag="TVR04_000978"
     CDS             21064..22818
                     /locus_tag="TVR04_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1269679.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHVNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASSTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKISNSNKTALRQSLEEAKLKLSQPEGTYSEESLQGLQSAVTIGETYLNS
                     DPDQVTVDHAKNTVDSAVANLVDLTALNEAINQATPLLTDGKEYPKEAYDSLVQKLAA
                     AAKLQNSFNPSQEEVNEAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SEPLKELYNKAIEAAGTFYRTVSKDKERKGISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLIKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PIDPVDPVKPVDPEVKPEPKPESKPEAKKEDKKAADKQQVLPATADTANPFFTAAALA
                     VIACAGQLAIVSRRKESN"
     gene            22953..26921
                     /locus_tag="TVR04_000979"
     CDS             22953..26921
                     /locus_tag="TVR04_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1269680.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VAADTATAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSK
                     SQVAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVSPSKVGHGS
                     FLQDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYS
                     RRGKGDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKN
                     NGNDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVL
                     EREFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNAL
                     GDLYAANKADLEDKENGYVYKKMMLATAVAYCKEIKSFVVNYGGAYLASDPVLKYQAF
                     KELYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGY
                     SYTKYKNIGYGGADMRSADNQDQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAI
                     CWGLSNLGVAVNEVFGIPAVNIYQKGHEAYLVYRQDDQGNGIWDIRDSVYGNRWAISY
                     SRWGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVY
                     EAGSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYP
                     QVMVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTG
                     NPIETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNV
                     EDGILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEYLEVSLDNGQSWQA
                     YDGTERFNDNITVLARYQAHGTSLASDSVTYTFTTDSTDATMHYISIDDIQAVTYANE
                     QSGRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHS
                     AKVDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKF
                     VSGSAYRFFEDISSPIAAPVRNDILALKDGILTILKETNTATKEIESFTITNSGLTVA
                     TTEKNQAIQDRILETIKTLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPL
                     YVLAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAV
                     NTALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTGYALDRGAFQ
                     QL"
     gene            complement(27116..27961)
                     /locus_tag="TVR04_000980"
     CDS             complement(27116..27961)
                     /locus_tag="TVR04_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1269681.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLEVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKWLLFVLWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     LIVGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLLYIYVLPYYTTADVTFYHRLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            28366..29508
                     /gene="tgt"
                     /locus_tag="TVR04_000981"
     CDS             28366..29508
                     /gene="tgt"
                     /locus_tag="TVR04_000981"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1269682.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            30415..30765
                     /locus_tag="TVR04_000982"
     CDS             30415..30765
                     /locus_tag="TVR04_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269683.1"
                     /translation="MILARKESQANKGQKVPEVPKAPETPEKKEQPQALKEPETPKAP
                     EQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPFFTLAALSV
                     IASAGVLGLKKKQD"
     gene            31149..31286
                     /locus_tag="TVR04_000983"
     CDS             31149..31286
                     /locus_tag="TVR04_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1269684.1"
                     /translation="MHQNPTERSDLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
BASE COUNT         8980 a         6213 c         7404 g         8698 t
ORIGIN      
        1 atttagtttt cagaaaacaa tttcatacca aaacatcaaa tccttcgcta tactaatagt
       61 ggagggtttt atgatggaca acattatcaa ctttttaatt accgtaaaag atgaccgaga
      121 accttggaaa ataaaacatg tgttatcaga tatcgtcctt cttattttct ttgcgcgctt
      181 atctggagcg gaatactggg atgaaataga ggcatttggt caggcttatg aagctactct
      241 aaaaacggtt cttcagttgg aaaatgggat tccctcccat gatacccttc agagagtttt
      301 tgcgactttg gatccccaag tattggtaga agtcacccaa atgtggtcag acattctaga
      361 agaatcagac ttatcctcta ggaatctttt tagcttttcg aaacggctag tcgctattga
      421 tgggaaaacg attcgtggca atggcagcgc taagcagaaa gccttacata ttgtgaccgc
      481 ttatgcgacg gatttaggga tttcctatgg tcaagtagcg actaatgaga agagtaatga
      541 aatcactgcg attccagagt tattggatat gatttcagtc aaaggttgta tggtgagcat
      601 tgatgcgatg ggaactcaaa aggccattgc ggataagatt atcaagaaga aagctgatta
      661 ttgcttagct gttaaagaga atcagaagac cctgttagag gatattgtgc cattttttga
      721 gatgagtcaa gaggcggatg atcattatca caccgttgaa aaagcgcatg gtcaaataga
      781 gacgagagca tatgaagtga ttcatgatgt cagttggctg aggaagaccc atcctgaatt
      841 tggtcatatt caaagtattg gacgagctcg tattcatctt gataagaatg gtcaagaaag
      901 cgaagagtcc cgctacttta ttttaagttg tcaggttagc gctaaagagt tgtgtgacta
      961 tgtgagaggt cattggcaaa tagagagcat gcactggttg ctagatgttg tttttagaga
     1021 agatgccaat aagaccttga ataagcagtt agcttttaat ctgaacgtga tggataaatt
     1081 ttgcttagcc gtgcttaagc gcttggattt tggtaagaaa atgagcatga ggcgcaagaa
     1141 atatgcccta agtctgtcct ttgacaagta tttgaaaaaa ataacctagt tcaaaaaagg
     1201 gaaaatgggg aaaaaaggga aaaaagggga aaataacctc tcatgcgttt ggcgtgagca
     1261 atattgcttg cccattccta aaagcctgat atcgtgctat aataagaaga ctagactttt
     1321 tacatgggag aattcacatg acattttaca atcacaaagc cattgagcct aagtggcagg
     1381 ccttttgggc tgataatcat acctttaaaa cggggacaga tgcctcaaag cctaaatttt
     1441 atgctttaga tatgtttcct tatccttctg gtgcaggtct tcatgttggg catcctgagg
     1501 gttacactgc aactgatatt ttaagccgct ttaagcgtgc acagggttat aatgtcctcc
     1561 acccaatggg ctgggatgcc tttggtctgc ctgctgagca atacgcgatg gatactggta
     1621 atgacccagc tgtatttacg gccgaaaata ttgccaactt caagcgtcaa atcaatgcac
     1681 ttggcttctc atacgattgg gatcgcgaaa tcaatacgac tgatccaaat tactacaaat
     1741 ggacacagtg gattttcaca aaattgtatg aaaaaggcct agcctatgaa gctgaggtgc
     1801 ctgttaactg ggtcgaagaa ctcggaacag ccattgcgaa tgaggaggtt ctacctgatg
     1861 gcacatcaga gcgtggaggc tatccagttg tccgtaagcc catgcgccaa tggatgctca
     1921 aaatcacagc ctacgcagag cgcttgctcg cagatctaga ggaagtggat tggccagagt
     1981 caatcaagga tatgcagcgc aactggattg gtaaatcaac aggggctaat gtaaccttca
     2041 aggtcaaaga taccgataaa gacttcaccg tctttaccac acgacctgat accctgtttg
     2101 gtgcaaccta tgctgttttg gcaccagaac acgccttagt agatagcatt actacagcag
     2161 agcaagcgca ggctgttgct gagtacaaac gccaagcgag cctcaaatct gaccttgctc
     2221 gtaccgatct tgccaaggaa aaaacaggtg tctggacagg agcctatgcg atcaacccgg
     2281 tcaatggcaa agaaatgcct atctggattg cggattacgt gcttgcaagc tacggtacag
     2341 gtgctatcat ggcagtgcca gcgcatgatg agcgtgactg ggcatttgca aagcaattca
     2401 atcttgagat tattccagtg cttgaagggg gcaatgttga tgaggctgcc tacacagagg
     2461 acggtattca cattaattct ggcttcctag atggtcttga taaggctgct gcgattgcca
     2521 aaatggtggc atggctggaa gaaaccggtg tcggtcatga aaaggtctct tatcgcctac
     2581 gtgactggct gttcagtcgt cagcgctact ggggtgagcc aatcccaatc attcattggg
     2641 aggacggtac ctcgacagca gttcctgagc aggacctacc acttgttttg ccagtgacca
     2701 aggatattcg tccatctggt acaggagaat caccactagc taacttgact gactggcttg
     2761 aggtgactcg cgaggatggg gtcaaagggc gtcgtgagac caacaccatg ccacagtggg
     2821 ctggctcaag ctggtattac cttcgctata ttgatccaca taatgataag cagctggctg
     2881 ataaggacct attgaagcag tggctgccag tagatatcta cattggaggt gcagagcatg
     2941 ctgtgcttca cttgctctat gcgcgtttct ggcacaaggt gctctatgat ctgggtgtag
     3001 tgccaaccaa ggagccattc caaaagctct ttaaccaagg catgatttta ggaaccagct
     3061 atcgcgacca tcgtggagct cttgtagcta ctgataaggt tgacaagcgt gacggcagct
     3121 tctttcatat ggaaacaggc gaggagcttg agcaggcccc tgctaagatg tctaaatcac
     3181 tgaaaaacgt tgtcaaccca gacgatgtgg tggagcagta cggtgcagat accctgcgtg
     3241 tgtatgaaat gtttatgggg ccacttgatg cgtccattgc ttggtctgag gagggtctgg
     3301 aaggagcacg caagttccta gatcgtgttt accgtttgat cacgacaaag gaaattgttg
     3361 cagaaaatag cggagcttta gataaggctt accatgagac tgttaaggcg gtcacagaac
     3421 aaatcgaagg catgaaattc aacactgcta tcgcccagct catgattttt gtcaatgcag
     3481 ccaataaaga ggacgagctt tatgtggcat acgccaaagg cttcgttcaa ttgctggccc
     3541 catttgcccc acacctaggt gaagaattat ggcagatcct gacagcttca ggtcaatcca
     3601 tctcgtatgt tgcatggcca acccatgacg acagcaagct cgttgaaaat gatgtcgaaa
     3661 tcgttgttca aattaaagga aaggttaagg ctaagcttgt tgtggcaaaa gacctctcaa
     3721 gagaggagct agaaaaagta gccctagcac atgataaaat acaggctgaa attgcaggca
     3781 aggaagtgat aaaggttatc gctgttccta ataagctcgt taacattgtg gtgaaataaa
     3841 gaccctggca aaaaatgcct tccttataat tttgagccca atactataaa aagctgataa
     3901 ccactcgttt acatgagtgg ttattcttgt tttgtaacac gctattaaaa ctgatattaa
     3961 agaagcttga agataatagt aaaataaaac cctaaactta tttaataaat ggaggatttt
     4021 tcaacgtgaa aaaattagtt ttagccagtg cagcagcact tgtattagca ggagcaactg
     4081 taagtacagg aacagtaagt gcgaatagtt ataacaattg gaatttaaca cctgaacaaa
     4141 gagctaaaaa actgagagaa cttaaacttt ctagatcaaa gcgttcttta gtattgtcag
     4201 aacttgaacg taaaagaaaa tcaatggttg aaaacttgac tactggcttt tctgatttaa
     4261 ctgtaagtga aaaaagagaa tttataacat tagtcaaaag agcatatagc agtgaggaaa
     4321 ttgatagaat acataaagaa gctgtagaaa aagttattgc aaaaacaaat ctttatcacc
     4381 aatatgctca gttattaaga aaagggtata aagatgatgt agaaattgat caaagtaagt
     4441 tacctcttta tgaataccaa aatcttaaag aaattattag acatttaaaa aaataaaggc
     4501 tttttgtcca ctgtagtggg ttgactgata gctaatatct agagaggacc agactggtgc
     4561 tctcttttat gattaggaaa caaacaaaat catcttaaaa gggctttgta cgatataaaa
     4621 cagggttaag tgccttgaat tgattgcttg tttcgttttg gctgggcagt atgggctggc
     4681 ctatttttgt gttagcccga tattgttgtg atgtgtttgg ttattaatta gagattaatg
     4741 atagtgcttt aacagtgatt agagctagct ggaaattggc ttcagtacat ttttgaacac
     4801 attactgtgt gtttcttggt cttttttaaa acgcttacat cttttacaat tattgtatag
     4861 aaaatatcat atttattaac tgtgaaaaga ggtagttctt atggaaatgc tcctagctcc
     4921 cctaaactgg ttttcgcaaa atattttgca aaatccggct ttctttgtag gtcttttggt
     4981 tttgattggg tatttgctgc ttaaaaagcc cctgcatgaa gtatttgctg gctttgttaa
     5041 ggcaacggtt ggttacctga ttttgaatgt tggtgctggg ggcttggtta acacctttcg
     5101 cccaatccta gtggcattgg gtaagaaatt tgaattaaag gccgcagtta ttgaccctta
     5161 ctttggactt gcagcagcca ataccaagct agaggagatg ggattcatca gcgttgccac
     5221 cacagccctt ttgatcggtt ttggggtcaa tattttgcta gtggcgcttc gtaaggtgac
     5281 aaaggttcgt acgctcttta ttacgggtca tatcatggtg cagcaggcgg caaccatctc
     5341 tgtgtttgtt cttcttttaa tccctcagct tcaaaatgct tttggtgctt gggcggtcgg
     5401 tattatctgt ggcctttact gggctgtcag ctccaatatg acagttgagg cgactcagcg
     5461 cttgacaggt ggtggaggct ttgccattgg gcaccagcag cagtttgcga tctggtttgt
     5521 tgacaaggtg gcgcctttct ttggtaaaaa agaagagaac cttgacaatc tcaagctacc
     5581 aagcttttta acgatttttc atgatacggt ggttgcttct gccactctaa tgctggtttt
     5641 ctttggtgct atcttggctg tgcttggccc agacatgatg tctaatgcag aacttatagg
     5701 tactggtgcc tttaatccag ctaagcaggc cttctttatg tatattttgc aaacctcctt
     5761 aaccttctca gtttatctct ttatcctgat gcagggtgtg cgtatgtttg tgtcagagtt
     5821 gaccaatgcc ttccaaggga tttcaagtaa gctccttccg ggttcatttc ctgcggtgga
     5881 cgttgcagcg tcatatggct ttggctcttc aaacgctgtt ttgtcaggat ttacctttgg
     5941 gcttatcggt cagctaatca ctattgcact tcttgtgatc tttaaaaatc caatcttgat
     6001 catcacagga tttgttccgg tcttctttga taatgctgcg attgctgttt atgcagataa
     6061 gcgtggtggc tggaaggcag ctgttgctct atcctttata tcgggtattc ttcaggttgc
     6121 cttaggtgcg gtagcggttg gtctattggg cttgacaggt ggttatcatg gcaatattga
     6181 cctagtgctt ccttggcttc cattcggtta cctcttcaag ttccttggta ttgccggcta
     6241 tgtggtggta tgtgtcttct tacttgctat tccacaattg caatttgcaa aggctaagga
     6301 caaggaggct tattatcgcg gtgaagcaca ataagcaagg tgataatagc tgcttattcg
     6361 tcttttagca caggctggta ggagtttgtc gatatacttc tgcaggtctt cattcatatc
     6421 aaattatcat atattcggag gaaaataaaa tggttaaggt tcttacagca tgcggtaatg
     6481 gcatggggtc atcaatggtt attaaaatga aggttgaaaa cgcgcttcgt cagcttgggg
     6541 taactgatat tcagtctgct tcttgctcag tgggtgaggc aaagggactt gcttcaggct
     6601 atgacattgt ggttgcttct aatcacctga ttcatgaatt agatggacgt acaaagggcc
     6661 atttggttgg gttagataat cttatggacg acaacgaaat caaaaccaag ctacaggcgg
     6721 tgctttaggg cggctctgat gacatcagtg ttgcccacag caaaatgata gtgagcctaa
     6781 gagcaatcac ttggctctaa gctaagctgt agcaatcaac tttcagtaag gatagatgga
     6841 gtgagagttg tgaagagagg ttccagctct ttctctttat cagctagata ggagtggggc
     6901 aaaaagtgtc tagccaaaga atttgattta gaaaggatta gttatatgaa tttaaaaaaa
     6961 gcatttatcg aaaacaactc tattcgcttg ggtttgtcag cagctagctg gcaggaagcg
     7021 gttaagctgg ccgttcagcc tttgattgac agcggggcgg tgacctctga atattatgac
     7081 gctattatcg cgtcaactga aaaatacggg ccctattatg ttcttatgcc gggaatggcc
     7141 atgccacacg cagaggctgg tgtaggggtc aagcgaaatg cctttgcgct tatcacgctg
     7201 agtcagccag tgacattttc agatggtaaa gaggtttcgg tattgctaac cttggcagca
     7261 actgatcctt ctattcatac gacggttgcg attccacaga ttgtcgccct ctttgaattg
     7321 gaagacgcta tttcgcgctt aattgcctgt cgcactccag aggaggtttt ggctctggtg
     7381 gatgagtcca aaaacagtcc ttatttagaa ggcttggatt tggactctta aacaagccat
     7441 catcactaga taaatcaaac ataacagaaa gggtaggagc tcactactaa gcattgaagg
     7501 cggtgctacg ggctcttggt aaaaaatcat gacacatatt ccaaaattac aggttgcctt
     7561 agatcattct gatttgcaag gggcggttag ggctgctgtt gcagttggtc acgaggttga
     7621 tgtgatcgaa gcagggacag tttgcctgct tcaagtaggc agcgaattgg ttgaggtgct
     7681 gcgtagctta tttccagaga agatcatcgt agcagacacc aagtgtgcag acgctggcgg
     7741 tactgttgct aagaataatg ctaagcgtgg tgcggactgg atgacctgta tttgctgtgc
     7801 tacgattcca acgatggcag cagcactgaa agccatcaaa gaagagcgtg gggatcgtgg
     7861 cgagattcag gttgagctgt atggtgattg gacctatgag caggcacaat tgtggctaga
     7921 tgcaggcatt tcacaggcga tttaccatca atcacgtgac gccctacttg ctggtgaggt
     7981 gtggggtgaa aaagacctga acaaggtcaa agccctcatt gacatgggct ttcgtgtgtc
     8041 ggtgacgggt ggcttagata tcaataccct caagctcttt gaaggggttg atgtctttac
     8101 ctttattgca ggtcgtggta tcactgaagc agaggatcct gcagcagcgg cacgtgcctt
     8161 taaagacgag attcgacgca tttgggggta acaatatggc gcgtcctatt ggtatatatg
     8221 aaaaagcaac gccaaagcat tttacttggc tggaacgctt gcaatttgca aaggcattag
     8281 gctttgattt tgtagaaatg tctgtcgatg aatcagatgc tcgcctagcg cgcttggatt
     8341 ggagtaaaca ggagcgacta gacattgtca aggctattta tgaaacaggg gttcgtatcc
     8401 caagcatttg cttctctggt catcgtcgtt atccacttgg ctctagcaat ccagaaacag
     8461 aagcgacatc attagagcta atgaaaaaat gcattgtgct agcacaggat cttggtgtgc
     8521 gtaccattca attggctggc tatgacgttt attatgaaga aaaatcacct gaaacgcgtg
     8581 cacgctttat caaaaatctc agacaggcct gcacttgggc agaggaagca caggtcattt
     8641 tggctattga aatcatggac gatcctttta tcaactcaat tgagaaatac ctggctgtgg
     8701 aaaaagaaat tgactcccct tatctctttg tctatcctga tacgggtaat gtctctgcat
     8761 ggcataatga cctctggagt gaattttaca atgggcatcg gtctattgct gccttgcatc
     8821 taaaggacac ctatgctgtg acagaaacat ctaaagggca atttcgtgat gtgccatttg
     8881 gtcagggctg tgttgattgg gaagagctgt ttgatgtgct caagaaaacg cattatcatg
     8941 gcccattttt gattgaaatg tggtcagaaa attgtgagac tgtagaggag acaagagctg
     9001 ccatcaagga ggcacaggat ttcctttacc cattgattga gaaagcgggg ttacgctaaa
     9061 tggcaaaaga tctacaagaa atgcgagaac gtgtctgtgc agccaacaag gccctaccgc
     9121 tgcatgggct ggtgaaattt acctggggta atgtttcaga ggtctgtcgt gagctggaac
     9181 gtatcgtcat caagccaagc ggcgttgatt atgaccaatt aacaccggaa aatatggtcg
     9241 ttacagactt agatggcact attgttgagg gagagctgaa cccttcttct gatttgccaa
     9301 cccatgtgca attatacaag gcatggccag aggttggcgg gattgtgcac acacactcaa
     9361 cagaagcggt tggctgggca caggctgggc gagatattcc attttatggg acaactcatg
     9421 ctgattactt ttatggtccc attccatgtg ctcgctctct aactgctgat gaggttaatg
     9481 gagcctatga aaaagaaacg ggtacggtta ttttagagga atttgctagt cgtggtcttg
     9541 atccgatggc agtgcctggt attgttgttc gcaatcatgg tccctttact tggggcaaga
     9601 cgcctgaatt agcggtttat cactcagtgg tgctcgaaga ggtggccaag atgaaccgcc
     9661 tgacagaaca aatcaatcct cgtgtggagc cagctccaac ctatattatg gacaagcatt
     9721 accttagaaa gcatggtcca aatgcctatt atggccaaaa aggtagccgg cattaaggca
     9781 gcagctagta acttagtgag agctgcttag ctaggcttaa gatcaaggtg ttaaccactg
     9841 ttgcaatctg ggataaaaag cctcttgttt tagaaaagtt taataattaa ttcaaatatt
     9901 acaattataa aagaaaaaag cgaactaatt aggaatttta tcttcagaaa actaatgatc
     9961 gttcgttttt tcctatttag aaattgactt tggcctagta ttctttccta cagataggta
    10021 aaatggtaaa ctgataaggc tgtgtggtag tgatgtttta tagaagggag gtatgaacgt
    10081 gattattttg gataaaaaaa gctatgatct gctgtcatat ctgattcgat tgaaggaggc
    10141 tgagacagtc atggcgattt cagctgcctt gggtcagtcg cggcgcaaaa tctattatca
    10201 tttggataaa attaacgaag cgctgcccag ccatgttgct caaattgtct cctatcctcg
    10261 ggttggcatc ttgctaaata gtgagcaaaa ggctgcctgc caacagctcc tcaatgaagt
    10321 gacagattat cactatgtca tgaagggtga tgagcgcagg agcttatcag cgatttatat
    10381 tgcagtggca acagagcggg tgacgctgga taagctcatg atgattaatg atgtttccag
    10441 aaacaccatc ttaaatgatc ttgctgaact gagagaggaa ttgtctagct acaacaataa
    10501 gattcagctg catgccacca aggccaaggg ctattacttt gactgtcacc ctatggcttt
    10561 gattcagtac ctttacaagg tattggcagg tgtttatcag ggaggcaata gcagctttat
    10621 tgagcttttt gatcataagc tttctgagac acaaggcttg tcagcttatt tttcaaagga
    10681 ggttttggat tattttcacg aatacctctt tttgtctcag gctagcctag gcaaaacaat
    10741 taatattcag gatagtcagt ttatgctgca aattcttcct tttatcctgc ttagctatcg
    10801 caacatgcaa ttgcattctg agactaaaac agcgcttaaa agtgatttta acctgatttg
    10861 gaagcgcaag gaataccaga ttgctaaggc attggctagt gagctttacc acaatttcaa
    10921 gctgcattta gatgacattg aggtaggtat ggtagccatg ctgatgctat cctttagaaa
    10981 ggatcaggat caccatgttg aaagtcagga ttatgagcag atgcgagcca ctattggtga
    11041 ttttatcgat cagctggagc tgcgctatca gctgcatttt acccacaaaa aggacttgct
    11101 tagacagctg accaggcatt gcaaggccct tgtttatcga aaggcctatg ggattttttc
    11161 gatcaatcct ttaacagacc atattaagga aaaatacgag gagctctttg ctatggccca
    11221 atcctgtgct gtgatcttag agcaggcttg gcagatccgt ctaacagatg atgacgtggc
    11281 ttatctgacg attcatctag gaggagagct gcgccatagc catgctgatc aggaaaagac
    11341 caagcttgtt atcgtttcag atgatggcat tgggattcaa aagctgctgt tgaagcagtg
    11401 ccagcgttat ttgcccaatt gtcaaatcga ggctgtcttt acaacagagc aataccagag
    11461 tgtctttgat ttgatgtctg ttgacattgt ggtatcaaca acagacgcac tggaggctct
    11521 tgttcccata ctgattgtca atcctatttt gagcgatgat gacattatta gattgatccg
    11581 tttttcaaag caggggcgct tgagtgatag ctctcgtttt tcccttgagc tagaaaaggc
    11641 gatcgagacc attgttaagg acgatgctga ccgctatgcc ttgaaaacaa aaattgaaaa
    11701 gctcattcat cacgaattat tgtaagctac tagcttgcct attgataagg acccctcagc
    11761 tgtctattgg tttaggagaa ggctggggct tttagtttat tttgagccaa aattcagtcc
    11821 agttttgaac acaagaatgt gtgacacttg gtctttttat gagaataaag aaggtctata
    11881 cttagagtat agataaaaat tcattttgga ggaaacataa tggctaaagt acaagatata
    11941 actcgtgaat catggattct tagcaccttc ccagaatggg gaacctggct aaacgaagaa
    12001 attgaagaag aggtagtgcc tgaaggaaat ttctctatgt ggtggctagg taactgcggt
    12061 atctggatca aaacaccggg tggtgctaat gttgtcatgg acctatggtc caatcgtgga
    12121 aaggcaacta aaaaagtaaa agacatggtt cgtggtcacc aaatggccaa tatggcaggg
    12181 gttcgcaagc tacaaccaaa tctaagagct cagccaatgg ttattgatcc ctttatgatt
    12241 aatgagttag actattactt ggtgtctcat tatcatagtg accacattga tatcaatact
    12301 gcagcagcca ttatcaacaa tccaaagctt gaccatgtca aatttgttgg cccttatgag
    12361 tgcggcaaga tttgggagag ctggggtgtt ccaaaggatc gtatcatcgt ggtaaaacca
    12421 ggcgatagct ttgcattcaa ggatatcaag gttactgctg ttgaatcctt tgaccgtacc
    12481 tgtatcgtta ccttgccagt tgctggcgct gaggaaaatg gcggtgaatt ggcaggactt
    12541 ccagtgactg acgaagagtt agctcgcaaa accgttaact acatttttga aacaccagga
    12601 ggaaccatct atcatggtgc agactcccac ttctcaaact attttgctaa gcatggacgt
    12661 gactacgata ttgatgttgt cttgaacaat tatggtgaaa atccaatcgg tattcaggat
    12721 aagatgacct ctgttgacct acttcgtatg gcagaaaatc tccgcgccaa ggttgtcatt
    12781 ccggttcact atgatatctg gtcaaacttc atggcatcaa ctgatgaaat cctagagctt
    12841 tggaaaatgc gcaaggagcg cttgcaatat cagttccacc cattcatttg ggaggttggt
    12901 ggcaaataca cctatccaca ggatcaggat cgcatcgagt atcatcaccc acgtggcttt
    12961 gatgattgct tcctagaaga atcaaatatt cagtttaaag cccttctcta aacctatttt
    13021 gcctcatcta gccttgctag gtggggcttt tgatttatct agagtgctat tagacatgac
    13081 tagcagctat ggtcaaagca agctaacgct ttacttagca gatcttattg ctattgggag
    13141 cttgcttggc agtctaagca ttggtttggt tgcaggacaa gagtcagata ggtcaatcaa
    13201 gtcagctaga ggaggctgct gggtaagctc tcaaggcgct aagtgtcaga aaggcctgct
    13261 tgctgtggtc tgttcagggc tgttaagtgc ttggttgact agtgatatca ctgcttagga
    13321 cgatcctgat acttgggtag caagcgtcca gcttgacaaa aagtgaccat atattatata
    13381 attaatgtgt tctgtttagg cagactcttt ttttaagcaa aaagtgacct cattatttta
    13441 aaattgtggt ggcactttta gaaatctatt aagctaattt agctttaatc gaggaagaga
    13501 acaagagagg aaaagaatgg gaactatttt agaggtcaag catttaagta aattgtttgg
    13561 caaaaaacaa aaagcagctc ttgaaatgat caaggctggt aaaagtaaga gcgctatttt
    13621 taaaaagaca ggagttactg tcggggtcta tgatgccagc tttgaggttc aggaaggcga
    13681 aatttttgtg atcatgggac tttcaggcag cggcaaatca acgcttgtcc gtatgcttaa
    13741 tcggttaatt gagccctcag caggctctat tttattagag ggaagggata tttctaaaat
    13801 gtctgtggat cagctcagag aagttcgcag gcatgatatg aatatggttt ttcaaagctt
    13861 tgctcttttt ccacacaaga cgattttgga aaacacagag tttggcttgg agctgcgtgg
    13921 ggtaccaaag caggagcgtc gagagattgc aaagcgtgcg cttgatcagt cagggcttct
    13981 tgaggtcagg gaccaatacc ctgatcaatt gtctggtggc atgcagcagc gtgttggctt
    14041 ggcgcgtgcc ttggcaaaca gccctaagat tttgctgatg gacgaggctt tttctgcctt
    14101 agatcccttg attcgtcgtg acatgcaaga tgagctgtta gagttacagg agacgatgaa
    14161 gcagaccatt atttttatca gtcacgactt gaatgaggct ctgcgtattg gtgatcgtat
    14221 tgccttgatg aaggacggtc agatcatgca gattgggacg ggtgaggata ttctaaccaa
    14281 tccggccaat gattttgttc gtgaatttgt agaggacgtt gaccgctcaa aggtgctgac
    14341 tgctcagcat attatgatta agcctattac aacgacagtt gatctggacg gtccgcaggt
    14401 ggctttgaac cgtatgcaca atgaggaggt gtctatgctc atggcaacca atcgtcgtcg
    14461 tcagctaata ggaagtctaa cagcagatgg agcgattgaa gcgcgtcaga aaaagctccc
    14521 cttgtcagag gtaattgatc gtaatgtcag aacggtctca aaggatactg ttattacgga
    14581 tattttaccc ttgatttatg actcatctgc gccaattgca gtgacagatg agcagcaccg
    14641 cttgctaggg gttattattc gtgggcgtgt ccttgaagcc ttggctaata ttccagatga
    14701 cgaccttaat tagaatggag agactgtatt ttggaaaacc tattacaaac aactttacca
    14761 gtggcacagc tggttgagca actaactgag tggctgacaa aaaccttttc aggcttcttt
    14821 gatctgctgc agcttgtggg caatgctttg atggattgga ttacacagac ccttttgttt
    14881 atcaatccat tattgtttat gctattggtt acctgtgcga tgtttttctt ggcaagaaaa
    14941 aaatggcctt tgccgatctt taccctcctg ggtctgttat ttgtctataa tcaaggcctg
    15001 tgggcagagc tgatcaatac ctttacgctg gttttggtag caagtctcat atctatcttg
    15061 cttggtattc ccttgggcat ttggatggct aaaaataaga ctgttcacca ggtgattaat
    15121 ccaatgctgg accttatgca gaccatgcca gcctttgttt atttgattcc ggctgtagcc
    15181 ttttttggca ttggtatggt ccctggtgtc tttgcgtcgg ttatctttgc cttgccgccg
    15241 actgttcgct ttaccaattt agcgattcgt catattccga cagaattggt tgaggcttca
    15301 gatgcctttg ggtcaacccc taaacaaaaa ttactgaagg tcgaattacc cttggcaaag
    15361 catacgatta tggcaggtgt taatcagacc atgatgttgg ctttatcaat ggttgtgaca
    15421 ggctcaatga ttggtgctcc aggtcttgga cgtgaggtcc tatcggcctt gcagcatgct
    15481 gatattgggc gtggctttgt tagtggcttg gcccttgtta tcttggcgat tattttggat
    15541 cgtatgaccc agcattttaa cggtaagcca caagaaagga cgcagactgg caaaaccaag
    15601 aaatggcttg gtctagctgc tttagctgtc tttttgttgt cagctttggg acgtggtttt
    15661 gctgcgatgt catcaagctc atcagacaag gggcaaaagg tgaccattgc ttatgtgcag
    15721 tgggattctg aggtggcttc tacccatgtt atcgctcagg tcttaagaga tgagggctat
    15781 caggtcacct tgacgccact tgataatgct gtgatgtggc aaaccatcgc aaatggcgat
    15841 gcagactttt caacaagtgc ctggttacca gtgacccacc agcagcagta tcaaaaatat
    15901 caggataagc tggacaacct tggccctaat ctgaagggaa caaagctagg actcgctgtg
    15961 ccagcctata tgagcgatgt gaacagcata gaggagcttt ctgaccaagc caatcaacag
    16021 attattggga ttgaaccggg agctggtatt atgactgctg ctgataagac gcaaagggcc
    16081 tattccaact tgacagattg ggagctcatt gctgcttcga caggtgctat gaccacctca
    16141 cttgatcaag ccatcaagaa aaaagagccg atcgttgtga cggcttggtc tcctcattgg
    16201 atatttgcta agtacgattt gaaatacctg gcagatccaa agaaaacctt tggttcaaag
    16261 gaaaatatca ataccattgc acgtaagggc ctaaaggccg atctgccagc tgtttatagg
    16321 attgttgatc acttttactg gactcaagag gatatggagg ctgtcatgct tgacatcaat
    16381 cagggcatga caccagaagc cgcagccaag aaatgggtgg ccagccatgc tgataaggtg
    16441 gccaaatgga ctcaatcata aggctgcttg ctcagatgga gcttagccta atcatggatt
    16501 ttgcagaagg ctttccgtcc atatcagttg aggaaagtca tagcagatga tgtcatcaat
    16561 ttggagattg agacaaagtc tgacttcaaa tagaacaaat gaacaggttt agttttctga
    16621 ggttttgaaa actaggcctg ttcgtttgtt aatgaattag ataacaaagg atattagtta
    16681 agaatctcta aagtgtcact ctttttatct cagtctcttt tttggtagaa atgttttgct
    16741 gataaagcaa aattggacct tttgatcaag ctacgggtat gctgctttac ctgctggtgc
    16801 ttgcaaaaag cgaagctggt cagagcaaag caggtcactg tgtggtataa taaaggcatg
    16861 gaaaacaaga ataaattact tttgattgat ggctcctcag tggcctttcg tgcctttttt
    16921 gccctctata accagattga ccgctttaaa aatcacagcg gtcttcacac taatgcgatt
    16981 tatggctttc atttgatgct agaccacatg atgaagcgtg ttcagccgac gcatgtccta
    17041 gtggcctttg acgcgggtaa aacaaccttt cggacagagc tttttgctga ttacaaggca
    17101 ggacgtgcta agacgcctga tgaatttcga gagcagtttc cttatattcg tgatatgctg
    17161 ggagcgcttg gtattgcctt ttatgagcta gagcattacg aggcagacga tattatcgga
    17221 acgcttgata aaatggcaga gcgcacagag cttccttttg atgtgactat tgttagcggt
    17281 gacaaggatt tgattcagct gacagatgca aataccgttg ttgagatttc taaaaaagga
    17341 gttgctgagt ttgaagagtt taccccagcc tacctcatgg acaaaatggg gcttacgcca
    17401 gagcaattca ttgacttgaa agcgctcatg ggagacaagt ctgataatat tccaggagtg
    17461 accaaaattg gggaaaaaac aggtttaaag ctcttgcacg aatatggcag cctagaaggc
    17521 atctaccagc atgtggatag ctttaagcca tcaaaaatga aggaaaacct gcttcatgat
    17581 aaggagcagg ccttcctctc aaagacactt gctactatca acaccagtgc tccgattacg
    17641 attggattgg aggatattgt ctatcagggt ccagatctag atcgcttgtc acaattttat
    17701 gatgagatgg attttgttca actaaaaaat gccttagcta gtcagctgcc acaggagccg
    17761 gtagctgaga ttgcttatca ggaagtcact gacataagag cggacatgtt ttcagatgat
    17821 acagtgtttt attttgaggc tttgagggat aattatcacc gcgaggagct gattggcttt
    17881 gcttggggca accaaggcca gatttatgct tcagcagata ttagcctcct cacaacagag
    17941 ctctttaaaa aggttcttga gcagccgatt gctacctatg attttaagcg cagtaaggtg
    18001 ctgcttagtc acctagggct tgatttgctg gctgccagct atgatgcccg cttggctaat
    18061 tacctcttat caactgtaga ggacaatgaa atggctactt tggcacgtct ttacaccact
    18121 ataccactgg atacagatga ggttgtttat ggtaaggggg tcaagcgtgc tgtgcctgac
    18181 aaggctgttt tgttaggaca tctggcgcgt aaggttcagg tcttgctgga tagtagacca
    18241 gtcatgcttg ataagctggc agagcatgag caggctgatc tctacactga cattgaactg
    18301 ccgcttgcca atgtccttgc gaaaatggaa atcgaaggca ttgctgtcaa tcaagatagc
    18361 ctgcaggaaa tggcagagca aaataaggtg gtcatcgagg agctgacaca ggagatctat
    18421 gaaatggctg gtgaggtttt taacattaat tctccaaagc agctaggagt gatactcttt
    18481 gagaaaatgc agctccctct tcatttgaca aagaaaacca agacaggcta ttcaacggct
    18541 gttgatgtct tggagcgctt agcgccaatc gcgccaatcg tggctaagat cttggactat
    18601 cgtcaaatta ctaagctgca atcaacctat gtgattggac tgcaggatta catcatggct
    18661 gatggcagga tccacacccg ctatttacag gatttaaccc agacaggccg actttccagt
    18721 gttgatccta acctgcaaaa tatcccgatt cgtctggagc aggggcgctt gattcgtaag
    18781 gcctttaccc cttctcatga tgacgctgtt ttgcttagct cggattattc gcaaattgaa
    18841 ttgcgtgttt tagcacatat ttcaggagat gagcatttga ttgctgcttt taaggaggga
    18901 gcggatatcc atacctcaac ggcaatgcgt gtctttggta ttgaaaagcc agaggacgtc
    18961 actgccaatg accgtcggaa tgctaaggct gttaactttg gcattgtgta tgggatttct
    19021 gactttggct tgtctaataa ccttggaatt ccaagaaagc aggccaaggc ttatattgac
    19081 acctactttg agcgctaccc tggtatcaag gcttacatgg aaagggttgt gcgtgaagcc
    19141 aaggataagg gctatgttga gacgctcttt aagcgccgtc gtcaattgcc agatatcaat
    19201 tctcgtcagt tcaacgttcg ctcctttgca gagcgtacag ctattaattc acccattcaa
    19261 ggcagcgcag ccgatattct caaaattgcg atgataaatc ttgaccaagc cctagtagct
    19321 ggtggctttg agaccaaaat gctgcttcag gtgcatgatg agattgtact tgaggtgcca
    19381 aaccatgagc tagcggctgt taaagagctg gtcaaagaaa caatggaatc agctgtcaat
    19441 ctggcagttc cgctgcgtgt agacgaaagt gctggcaaga gctggtatga ggccaagtag
    19501 gctagattag cactggtgtt aagtggcagc ctgcttggcg tggctgctgt tattccttgt
    19561 gttccgcatt ttaaaaactt atgctataat gaagagaaaa aaacagcagg gcatgtcatg
    19621 ctaaggaggg ttttccttga gcttggtagc cagatggttg gctaagtcat accggcagcg
    19681 attgtctttt cctgttgttg atttgctatt gggtgtgctt gataaaaaag gaagtaaatg
    19741 atgattgata catttcaaaa tccctctgat gagactatcg tctcttatct tgaatctgcc
    19801 aagaccattg cagtggttgg cttatctgat cgtcaaacca ctgctgctta tgatgtggct
    19861 aggtttatgc aggctaaggg ctaccggatt gtccctgtca atcctaggct ggcaggtcag
    19921 tctgttttag gagaggtcgt ttatgctagc cttgcggcta ttccttttga ggtggatatt
    19981 gtcaatgtct ttcgacgaag tgagtatttg cctcaggttg ctcaggactt tttagcttgt
    20041 cagggtcagg tcttttgggc acagcttggc ttgtatagcc aagaagctga ggagcttttg
    20101 cgatcagcag gcaaagctga cattgttatg aaccgctgta tcaagattga ctatttacgg
    20161 ctaatcagca agcaggatca agattcctgc tagttagtga cgcagttaca aaaggaggag
    20221 gttgtaagct tggacattca ttcacatcag caagctctaa atgcctatga aaatgtccta
    20281 gagcatctac gtgacaagca tattcgtatt accgagacgc gtaaggcgat catttcttac
    20341 atgattcagt ccactgagca ccccagcgca gataaaatct atcgtgattt acagcctcaa
    20401 taccctaata tgagccttgc tacggtgtat aataatttga aggttcttgt tgatgagggc
    20461 tttgtatccg agctgaaaat tagtaatgat ttgacgacct attatgactt tatgggacat
    20521 cagcatgtca atgttgtttg tgaggtctgc gggacaatcg ctgattttat ggacgtagat
    20581 gtaatggata tcgctaaaga agcacaccag caaacaggct ataaggtcac ccgtattcca
    20641 gttatagcct acggtgtttg ccctagctgt caggctaagc aggacaagga tacagactat
    20701 tgagggttgg ttttttggat cttggctgct cgtgtagctg atgatatggt acaaagtcta
    20761 gaagagagag ttagagactc gctctttttt tgttggctga aaaaccttta gcgatcacta
    20821 ttgacaataa aaaatgttat agaccagatt ggtgtcttta tctttgttat atttttaaaa
    20881 aatttaacaa aaaatccgtt tgcatattga cttttcttaa aattttttgt aaattataag
    20941 tgatatttga gtgtcacaat caggctaata tcagagtggc agctactaag tgatagcagc
    21001 tgccctatga cacatattgc tattgttcga gcttgctagg gctctagaaa aggaaaaaga
    21061 agaatgaaga aattcacgaa acggtgtctt aagggctgcg gtcttgttgg attagttttc
    21121 agcacaggac tggttgcctt gtcggataat attgatagcg ctttaacagt aggggcggaa
    21181 acgactactg ctagtgcatt tgaaaataat gggacaggtc aacatgtgaa ctggcacata
    21241 gatattccac aagaatatac agttgaatta ggagaaccaa ttactatctc agatcttatg
    21301 agtcaaatta cggttactcg taaaggtagt aatgggactg ttaatgatgg agatactttt
    21361 gactttattt cgaatggaga tggttcaaga ggaattgata cccctggagt aaaaatatgg
    21421 tttgactttt acaatgctgc gggtacttcc tttttaactg atgaaatgtt agcttcgtct
    21481 acatatgctg taccgggggg atcttatact attaaagctt gggtattcta tgggaaaaat
    21541 gataccaaaa agctcttcac atttaaacta aaaatttcta acagcaataa aaccgcattg
    21601 aggcagtcgt tagaggaggc taagctaaag cttagccagc ctgaaggaac ttattctgag
    21661 gaatcactgc aaggcttgca atcagcggtt actattggtg agacctattt gaatagtgac
    21721 cctgatcaag taacggtaga tcacgcaaaa aatactgttg attccgctgt tgctaatctt
    21781 gttgatctta ctgccttaaa tgaagctatt aaccaagcaa caccgttgtt aacagatggt
    21841 aaggagtatc ctaaagaagc gtatgatagc cttgttcaaa agcttgcagc agcagctaag
    21901 cttcaaaatt cctttaaccc atcacaagaa gaagttaacg aggctgcgac tgatttaacg
    21961 caagctctta cgacgcttaa gactgctgta gcgcatgaag ccttagatca agccttggct
    22021 aagctgttag agctttaccg agaaaatcca aaccttgctt tgacatcaga gcctttgaag
    22081 gaattgtaca ataaggccat tgaagcagca ggcaccttct atagaactgt tagcaaggat
    22141 aaagagagaa aaggcatttc cctttatgag ctagagcgtt acactacaga aacaaactca
    22201 gttgttgata ctattttaaa ggtaaaggct gcaattgccg aagaaggaaa ggcaaaattg
    22261 cgttctgctt tagaccaatt aaatgctctt atcggagaaa atctagacct atctccatat
    22321 acagcagctt ctgctcaagc ctatacagac cagctagcta aggctaagga ggttgcagca
    22381 gcgggtgaga cagcttatgc tcaggagaca gaaccgacag ctattactaa cagcttgatt
    22441 aaggtgctaa atgctaagaa atccctctca gatgccaagg cagcattggt tgctaaaccg
    22501 gtagatccgg tagacccagt agatccggta gacccagtag acccggtaga cccagtggat
    22561 ccggtagacc cagtggatcc ggtagaccca attgatccag tagatccagt aaaaccagtc
    22621 gatcctgagg ttaagccaga gcctaaacca gaatctaagc ctgaagctaa gaaggaggac
    22681 aagaaagcag ctgataagca gcaagtgctt ccggcaactg ctgatacagc taacccattc
    22741 tttacagcag cagctcttgc agttattgct tgtgcaggcc agcttgctat tgtgtcaaga
    22801 cgcaaagaat caaattaact gtaggcgatg attttccccc tttaattaat ttcctatagt
    22861 acgatatctt tgttggactg attatcaact gtagtggttg gtggtcagtc tttattttgc
    22921 ttaaatgttt tatgtttaaa ggagaagaca ccatgttcaa accttatact gatggtaagc
    22981 agcgctttgc cattaaaacc tttaaaacag gtgcagcctc tgtgttggtt gcaaccttat
    23041 ttttaacact agggctgaca actgtttctg ctgatgagca gcaggtggct gcggatacag
    23101 ctacagccat agcaaccacg ttagaagcac aagaagcggt tgatcaacaa gcagctgatc
    23161 aatcagcaac cgctgcgcaa gacacagcag ctgagggctc ctcagaaacg ctgccagtag
    23221 taataggtac tgccactaca gaaacaactg actctaagag tcaagtagcc gcagcagagc
    23281 aagctaccga agcttctgcc gaagagacca caaagcagga gcagacagaa gtatcacaag
    23341 cagtagagac caccaataag actgaagcta aggactatat ctacttatca gatgagacac
    23401 gtgtcagccc gtccaaggtt ggacatggca gctttttaca ggacaaaaac cctgccggtg
    23461 gcaccattac tctagtagtt gatggagagg tgcttgcatt tgataaggga attgcagtgc
    23521 atgctccttc acagctttat tatgatgttg aacaatactc caatgaatac acacgtctat
    23581 cagcctacct aggagttgac tatagtagac gtggtaaggg cgatggtgta agctttaaca
    23641 tctataagtc taaggacgga aaaagttggg aaagcctggt gacaactggt acagtaaccg
    23701 gaaccagtga ggctgtttat gttgatctag atattacagg tgctaaatat gtaaagctaa
    23761 ttgcaaattc actaaaaaat aacggtaatg atcactctgt ttatgcagat ctcaggttgc
    23821 tcaaaacaga ttatgattta tcaagcgagg tgtcttatga caggctaaag acaactgaag
    23881 agtatgatgc ccttctcagc aagaatagtg tcacagataa ttatgataat ccagacaatt
    23941 tggcattagt gcttgagcgc gaatttgtca atcgtgtcgg ctaccacacc attcaatctg
    24001 ctgtcaagaa aaatgaaaag gtcaaggtcg ctcttgattg gctattgtca gatgaggacg
    24061 ctctgtcact gtttttagag gcaggctcga tgtttaacgg ctctacccta aaaaccttga
    24121 acgccttagg agacctttat gctgctaata aggcagattt ggaggacaag gaaaatggct
    24181 atgtctacaa aaaaatgatg ctggcgaccg ctgttgctta ctgcaaggag atcaaatcct
    24241 ttgtggttaa ctatggtggt gcctaccttg cttctgaccc tgtgctgaaa tatcaggcct
    24301 ttaaggaatt gtatcgagac aacgaattct taaggaaaga agaatttgcc aactacaata
    24361 tggagttggt gcgtgctgtt atggacgcca aaatagatga cgaggaaatt ctctggctgc
    24421 accattacgc cgaacaaaaa tatggagata aggttgctag ctataccagt ggctactctt
    24481 atacgaaata caaaaacatc ggctatggtg gtgcagacat gcgcagcgct gacaatcaag
    24541 accaatggac agaaaaatac cagctcgttg gcaccctcaa tgacgatgcc tttaatgtta
    24601 cttatgacaa ccgtcaccgg atctggatgc tgatggaaaa aggagctatt tgttgggggt
    24661 tatcaaactt aggtgtagca gtcaatgagg tctttggtat tccagcggtc aatatttacc
    24721 aaaaaggtca cgaggcttat ttggtttacc gtcaagatga tcagggcaat gggatttggg
    24781 atattagaga cagtgtttat ggtaatcgct gggcaatctc ttattctcgc tggggaacca
    24841 caacagcaac agaggctaga ctcttgcttg gctggggcct aaaatcctac aatgacattc
    24901 ataaaaacgc tagctatatg ctgctggcgc aagcagcctt aaaccaatac gataagttca
    24961 aggaatcgct ttattataat ctcatcgcta atgtctacga ggctggcagt gatcaacaga
    25021 ttgaggccta cagcaaggcc ttagatgtac tagagcttaa tctagatact tacgatggct
    25081 tgatagaggc ctatgcaaaa aatggtcaaa aaacagatca agactggctg gacttaggaa
    25141 agcgtgtcat tgcagcttac acctactatc cacaggtcat ggtggaggct atcaagcgta
    25201 tcacgcctaa tatcagcgat caagcagcta aggctgagct agatttgctg agctataacg
    25261 ccctaatcgc agccaaaaca gcaactgata aggaagtgct ccaatctaat gaggttagaa
    25321 ttatcgccaa ctatatccta acgggcaatc caatcgaaac agcaagcttt agctttgatg
    25381 acaagaccct tcgtttgcat gagaattatc aggatacaga tttgacagtc cgctattcta
    25441 ttgataatgg gaaaacatgg cttgaaacca aggacaaggt tatcgttttt agtgatgacc
    25501 ttttggccaa gcttaacgta gaggacggta ttttagttgg ctttgacgcg gtatctgcta
    25561 cctacaggat taacctgaca aaggcagcag caccgaccaa cagcagcctt tatggcaatg
    25621 acttggaaaa tcgcttgatt ggtgctattg agtatttgga ggttagtcta gataatggac
    25681 aatcttggca ggcttatgat ggcacagagc gcttcaatga caacatcaca gttcttgctc
    25741 gctatcaggc tcatggtacc agtctagcaa gtgacagcgt tacttatacc tttaccacag
    25801 acagcactga tgctacaatg cactacatct cgattgatga tattcaggcg gtgacctatg
    25861 ctaatgagca atcaggcaga tctggcaagc acatggtaga tggtagagat atggctaccc
    25921 aatggcatac cttatttaat caggttactg aggacaagtc atatactgtt gagtttaagg
    25981 acgataaaaa cttctctgct attgcctatc tcccaggagg tgttaatggt atgatccatt
    26041 ctgcaaaggt cgacatcagc tcagacggta aggtctggac aacggttgtc gatagcactg
    26101 attggaagca aaatactgag ctaaaaacag tcagctttac accaacaaca ggtcgatttg
    26161 ttagaataac tgccttagac acctatggaa agagtagtgg acaggccaat aaatttgtca
    26221 gcggctctgc ttatcgcttc tttgaagata tctctagccc cattgcagca ccggttagaa
    26281 atgacattct agcgcttaaa gacggtattt taaccattct aaaagagacc aatacagcta
    26341 ccaaggagat tgagagcttt actattacaa atagtggtct aacagtagca acaactgaaa
    26401 aaaatcaagc gatccaagac aggattttag agacaatcaa aaccttgggt cttacaggga
    26461 cttattacat tactcttgag aacactggta cttatgatga cttagctgat ttgctgaacc
    26521 atcagcttgt cattacctat caggataagg cagcaggccc cttgtatgta ttggcgatga
    26581 atagcctctc atcaggcgat gaagccttag atgctgaata cagcctagac ttgatcaaat
    26641 cagccttaaa atcagcttta gagtcagaaa acatagattt aaagactttt gaaggcttat
    26701 caatctctag tcaattacca gcagcaaaga ccgctgttaa taccgcctta atggaaaagc
    26761 tacaacagct tcttccaggg gattatttca ttgacctagc aggtctgcca acagcagcct
    26821 caattgatga gctattagat agccagctct ttatttacta tcgtgagagt cattggacga
    26881 ccggctatgc cttagaccga ggtgcttttc agcagctcta ggatagcctt gggttaacat
    26941 tgctaaaaga gggcctgtaa gcaagccttc caaccgttag atgtgtcatc tagctttgga
    27001 caggcagctg ataggctcct ctttttgatc taaaaaagtt atcaaaagtc atgcaaaaaa
    27061 cctctatatc cactctgaac aaggtcatga gagacataga ggaatatcgt taaggctagc
    27121 taatagcaga tggggcttct tttgaacctg tgatagtaag cctttcagca tctatcggca
    27181 gctctgtttc atcgtgaatg tgttttaaac ggtggtaaaa ggtcacatca gcagtggtgt
    27241 aataaggcag tacgtagata tagagcaggc caaaagacaa gatcactagg ataaaccagc
    27301 caataaagct aaggtgcagt aaaaaatact ttcctttgta gcctgagatc atgtccttgc
    27361 tctcttcgat tgccgtaata gcacccatat aggtgccttc cttgaccttg tcatagagaa
    27421 tgtactcagc catgctgtaa gcacaataac gattcatata aacgataagg ccgacaatta
    27481 aaatcacaaa accaataacc ataaagatga ttggagtcat cacagcagca ccagtattgt
    27541 agcttgtcag taatgccgca gagctaatcg ttaggataac caagccaaca atccaaatca
    27601 aagaccatag gacaaataag agccatttga tgatcaacaa aacaagaacc ttgccaaaca
    27661 agtttccaga aaaagctatc gttgcctctg aaaaagagac ctcacgacga tagtagcgga
    27721 taacctctag catggtgtag gctgctgata gggtaaagac cgtcagcatt atcagaacaa
    27781 tcaaaggaaa gtagcttgcc ccgactgata cctcaatccc ctgagtggtc acataggttt
    27841 gatgaacctc aattcctgag taaaaaatag ataagattat cggtactaaa aataagaggt
    27901 atttcccctt tagtcccttt aaagtctgtc tagcttcacg ttttatttct ctaattgaca
    27961 tcgtacaact cctttggtac attataccat attctaggag ccagtgatac ccatcaccat
    28021 tgctcccacg acaaatacgc gaaacagtta tttctgaatg atagtataga gtaaagcaaa
    28081 cattttcaac gatttttctg tagtaaagtt tataaaagat aagacatata cttgaaatag
    28141 ctgaacattg aacgacagaa agctttcttt tcttgctaaa actccttcat gcgtctgtcg
    28201 tgccattgct tcgggatctt atctctttga gggcatgaca agtcagagat tttttgataa
    28261 aatgataggg ctctaaacaa gcccataccg cttgactaag tgctttgtaa gtggtatgca
    28321 aaacgctcaa gactgtttat cttgatagca aggaaaaaag aaacaatgac taattaccct
    28381 attacttatc gtttgatcaa aaaggaaaag catacaggtg ctcgtctcgg tgagattatc
    28441 accccgcatg ggacctttcc gacgcccatg tttatgccgg tagggacaca ggcgacggtt
    28501 aaaacacagt ctcctgagga gctcaaggag attgggtcag gcattatttt atcaaatacc
    28561 taccacctat ggctacgacc aggagatgag ctgattgcgc gtgcaggtgg ccttcacaaa
    28621 tttatgaact gggatcaggc aattctgaca gactcaggcg gctttcaggt ttattccttg
    28681 gcagactcca gaaacatcac tgaggagggg gtgaccttta aaaatcacct gaatggctca
    28741 aagatgtttt tatcaccaga gaaagcgatc tccattcaaa ataacctagg ctctgatatt
    28801 atgatgagct ttgatgagtg cccgcaattc taccagcctt atgactatgt taaaaaatca
    28861 atcgagcgta ctagccgttg ggcagagcgt ggcttgaagg ctcaccgccg tcctcatgat
    28921 caagggctct ttggtatcgt gcagggagct ggctttgagg acctgcgtcg tcaatctgct
    28981 gcagacctgg tagctatgga ttttcctggc tattctatcg gtggcttggc agttggtgag
    29041 agccatgctg agatgaatgc tgtccttgat ttcacaacgc cacttttacc tgaaaataag
    29101 ccacgctacc tgatgggggt aggtgcacct gatagcctga ttgatggggt gattcgtggg
    29161 gttgacatgt ttgactgcgt cctgccgacg cgtatcgctc gcaatggcac ctgcatgacc
    29221 agcgagggcc gtctcgttgt gaaaaatgct aagtttgcag aggactttac cccacttgac
    29281 catcattgtg actgctacac ctgtcagcat tacacacgtg cttacctacg tcatctccta
    29341 aaggctgatg agacctttgg catgcgcttg accagttacc ataacctata cttcttagta
    29401 aacctcatga agcaggtgcg tcaagctatc ttggacgata accttttaga gtttcgtcag
    29461 gatttccttg agcgctatgg ctacaacagc tccagtcgta atttttaagc tgatagccgc
    29521 ctaaaagcgg tagctttcca caataacaga taatagcagc aagggtctgg gctttcgcct
    29581 aggcctttta agcgtgctta tcaggagcaa tctctctgac gaagcctaga ttggcgatca
    29641 tgataaaaaa gtctgacact aaaaaagcca gccttcatta tctatcagag ccggcatact
    29701 agtaaagcct tggtagccta ggctttctcg ctccacaaac agaaatattc ctcgacagat
    29761 acgtcagaat attggtgctt taattagaaa aaaacgaaac tacggaagcg aaatctccaa
    29821 aacatattca cagcctacaa gcgtcatgtt aagattttct ttggaataaa aaagattaga
    29881 aatcattaac gtttctaaac taaaaggaga gaaacatgag aaataagaaa acaagtgtca
    29941 ggcttgttaa gaagtacggt atctgctcag cagttgtcgc cctagcaacc attgctagct
    30001 tagggacggt tacaggtaaa gctgacgaaa aatatcccac tatggataat ccagcttatt
    30061 tttttaaaag atttatagat catgaaaaaa gagctcctgg ggaggctaca tggaaggatt
    30121 gggaaagtta tagttcctac aatcatggta ccatgatagc caacatttta agatatttat
    30181 ggcatgtaga gaagttttta accccatcaa ctggtaaatc caacctcctc tatcagctat
    30241 atgagtcaga ttctcttaga ggacctcaag gtccaatggg tcccgcaggt cctcgaggcg
    30301 aacgaggccc acaaggagct caaggccttc gaggggaacg cggaccagtt ggtgagcgtg
    30361 gaccaatagg cccacaggga ccagaaggaa aaccaggtca acaagggcca aaaggtgata
    30421 ctggcccgca aggagagcca ggccaacaag ggccaaaagg tgccagaagt gccaaaggct
    30481 ccagaaacac cggagaaaaa agagcaacca caagcactaa aagaaccaga gactccaaag
    30541 gcaccggagc aatcccctgc tccacaggca ccaaaatctt cagagcagcc agctagtcca
    30601 aaggcaccag ctcctcagtc agcaccaaac aaatcagcgg ctccagcagc tcaaaagggc
    30661 acgctaccag ctacggggga ggcaaatcac ccattcttca cccttgcagc tctcagcgtc
    30721 attgctagcg caggtgtcct aggcttgaag aaaaaacaag actaacaatt gcatatctct
    30781 ctaacagata gctataaaag agggtcacag gaccctcttt tagtgatatg tcaggtagaa
    30841 ataaaggatt ttttcgaatg ctcagggaaa aacaaaagca atttagacga aatgccagct
    30901 tgcctccgaa acagtagctg aaaaaagagg gggctatact ctgtgagaaa gaagacctcg
    30961 tagtttaaat ggaaagccac ctaagacatc tagcatcttc tcttcagacc tatagtcaga
    31021 gcataaaaaa gccgcctgat tagtttaaga tttgacggat tcttgtgtga ttatgatata
    31081 ataatggttt ttgcagaaaa gttaaggcgg tggctcttag ttctgaaagg tggtgatgcc
    31141 tatgggcaat tcatcaaaat ccaacagaaa ggagcgattt attgtctact tacgaggccc
    31201 ttcaactcat gcttgctttt ggtagttttt tgcttacctt aatcagctta gttgttgcaa
    31261 tcgtcatatt aaacaataaa aaataaccgt ctgaa
//
LOCUS       DARYSY010000024        28980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYSY010000024 DARYSY010000000
VERSION     DARYSY010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28980
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..501
                     /locus_tag="TVR04_000984"
     CDS             <1..501
                     /locus_tag="TVR04_000984"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269685.1"
                     /translation="FEISSGGHICKNVIGGCSKSKGKHIFLYETLSDGKDKKGIIKIK
                     QTENLNTYISDIEKLLSENPLSDNSKQLICSKLRKAVEFAIDEIILNRQVPTKYSNKN
                     SRIHWDELKKIDNNPITIEKLHNIHGRCSGGALHNGTESEENPVDKDELANMLREIQT
                     IQTSHR"
     gene            812..4564
                     /locus_tag="TVR04_000985"
     CDS             812..4564
                     /locus_tag="TVR04_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
                     /protein_id="HEL1269686.1"
                     /translation="MKSINKCAILALSTLALAQSAQTVRSEATQVSSSLVTTVKLKDN
                     ILLFEEIGPYADKSEGKLYYKNIEKILIDGKEYDKKLEGDYSYDINYQGIKVNAKNIT
                     EGQHQLRIVNKTNGGILVVFDKKGNDVTFVSAKPSDDTTASPQQATAKTEKPAKVTSY
                     DGLATLSFITKLEATEGELLFPEIDRYSSTKQIKELAHQITKIKVNDQDYKDLVYDSV
                     KDKPGYVSDLKGLHLGTTAFKEGENKVVISSQSFEDVIITVKKSGEQYTFVSAKQKQG
                     QGSQQEAPQGLDFTKLESAIKEAERLIASEANKEQVKDLSSKLQVIKESYHHIDNETL
                     LKETYELLMDSIKAYQGTDLAVTDLKAGTYTLTFKANKENTEEASMLQGAFDKKAKLV
                     VKEDGKMEISLLNTALGQFLIDFSIESKGQYPTSVRTQVGERDINNNYIRSEFTLPIE
                     ELDKLHKGAVLVSAMGGQESDLHHYDKYTKLDMTFSATASKGWTGYQAEIDDKEKGIG
                     SERLEKVLVKLGKDLNGDGKMSPEEIAKIEGELRLDHYDLTDISLLKHAKHITELHLE
                     GNQIASIPKETFSQMTNLRFLNLRSNVITTLDKDTFAHNSQLKELYLSSNYMPNLEEG
                     LFRNLGQLDQLDLSKNRISVIRDGVFNGLSRLTSLALAENIITDFSENALASLDNLNF
                     FDVSENQLGSLPSSLSKLTKLSYIVANRNQILDIANIDFSHMPNLLTVDLASNELTKI
                     PQGAFKANKQLSKLNVYNNLLANISEADFADLKALDLDLKFNCLSGVSDKLRQLMGTN
                     KLNPQKQLANLSAALNHQAITYHQGFSLLDLYYWEQQTLSSTEAEISSIEDYNKRLKA
                     SSSDIIALLNERYADWDIVVQLQKKTSTGQYVTVDERRLNNDPQDELQGSFDLKGAGV
                     YRVRKALITKEFAKKREHIYLTSNDVEVKEDQLAGSGQSKGLDINKLEDGIYYIKASM
                     LKNDLQSESMSHQAIDHRVKLIVNKGVYSLEVTFKGMKIGNLTGYLGELSYFVDGYQR
                     DLTGRPVGKTEKAEVVSYFTDVTGKPLSDAYGSNYPQVLRFRLIDQAKKDGLVPLRVF
                     VPIMDAISKGTGFQTVFMKLDLQSLTKDKAQLPHSEDNQGHGTIGELLQPHTGIIGGH
                     TSPAIPNLTNLLAKKSAAPSSNAKEDAKTGTDKLKSLISSHKASKAGTGKASKQAAKT
                     RAKAKSKAAKHSQEQMKADHRGHIIIGLASFIVIAVGLILGRKKLF"
     gene            4793..5698
                     /locus_tag="TVR04_000986"
     CDS             4793..5698
                     /locus_tag="TVR04_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1269687.1"
                     /translation="MKIINEEHMIKRLFKKLIGGLVILLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYNVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSDLQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSTLKKQSSPSKKGQAAGLTTSLDKSKPESSQKPVNNPLSVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            5682..6566
                     /gene="isdE"
                     /locus_tag="TVR04_000987"
     CDS             5682..6566
                     /gene="isdE"
                     /locus_tag="TVR04_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1269688.1"
                     /translation="MKKVIKLIGLAVLSLALSACVDQHPKAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEIIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYQAFKKQ
                     HKGQKKPKVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWQHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVN"
     gene            6568..7590
                     /locus_tag="TVR04_000988"
     CDS             6568..7590
                     /locus_tag="TVR04_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1269689.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMLLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFSGLFVAYDPEVALIYDLRFPRIVIALLAGAGISTSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDLI"
     gene            7587..8369
                     /locus_tag="TVR04_000989"
     CDS             7587..8369
                     /locus_tag="TVR04_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269690.1"
                     /translation="MRHEQDLISVEDLSFTYRDRLILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAVSSISLKQFAKKVAVVHQDNQAVADLLVGDLV
                     AMARQAHRRFFKGPSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILTLIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEILDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            8415..10178
                     /locus_tag="TVR04_000990"
     CDS             8415..10178
                     /locus_tag="TVR04_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1269691.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTVADVLTVASQGIDSLDTYYSYYLSLAMRTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADKRYEESFVAKAEAFRRATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQG
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVAIDLASKQAINQEILYVSDQSTLLNMSIYENLAIATQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKKAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQAELEANLYG"
     gene            10171..11853
                     /locus_tag="TVR04_000991"
     CDS             10171..11853
                     /locus_tag="TVR04_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269692.1"
                     /translation="MVKNDYSTYQLVLRLLAMMKHLLVWIALAVVFAVLGFMLTVSIP
                     TSLAYLGLEVMAGHAIALKWLYLFIALALLRGLFRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRTYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKVIMKWYSW
                     QAGHIFLSEVDSQLLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACAEGLDTLVTGSADFSAGEAQRLELMRALLKRVDCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            11834..12427
                     /locus_tag="TVR04_000992"
     CDS             11834..12427
                     /locus_tag="TVR04_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1269693.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQIFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYHSRLVNLLSYFVFAFVNSGPIILMWLLKDAYIKSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCAFVGGLFGQYLLKKHFAKSGMLL"
     gene            12424..13107
                     /locus_tag="TVR04_000993"
     CDS             12424..13107
                     /locus_tag="TVR04_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1269694.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGILLGILFWLGQ
                     GRLAIGMTLLYALLLGLPVLPLHSSLPAYLFSQLSFVAVAGQLLYPSVLAALIFVKTT
                     TAYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQ
                     PRRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIL
                     ATIIYMVLQ"
     gene            13044..14498
                     /locus_tag="TVR04_000994"
     CDS             13044..14498
                     /locus_tag="TVR04_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269695.1"
                     /translation="MEGLGGTDLDTCNDNLHGSPVIKAKQLKFSYTNRRQTACELRDC
                     QVEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLRVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHAGVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLEHVLSSKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKKLEVRAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVPLSAKDRLSITSLVLQDVGLQLFAETVAKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVN
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLGR"
     gene            14876..16891
                     /gene="recG"
                     /locus_tag="TVR04_000995"
     CDS             14876..16891
                     /gene="recG"
                     /locus_tag="TVR04_000995"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1269696.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASIAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDTVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHQQLDSVL
                     AWVKTELAKGAQAYVISPLIEESETLDLKNAVALEAELKDYFKASASIALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVATEIVAAKNWQLDPRWAPILANLRVADQFD"
     gene            complement(17012..17977)
                     /locus_tag="TVR04_000996"
     CDS             complement(17012..17977)
                     /locus_tag="TVR04_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1269697.1"
                     /translation="MKEILVLHTGGTISMQADETGKVSPNQSNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGIVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYC
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18049..19437
                     /locus_tag="TVR04_000997"
     CDS             18049..19437
                     /locus_tag="TVR04_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HEL1269698.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILSRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(19724..20176)
                     /locus_tag="TVR04_000998"
     CDS             complement(19724..20176)
                     /locus_tag="TVR04_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1269699.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGATLILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLSSFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEKIDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            20452..21666
                     /locus_tag="TVR04_000999"
     CDS             20452..21666
                     /locus_tag="TVR04_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1269700.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITRVLKQYKR"
     gene            21838..22620
                     /gene="codY"
                     /locus_tag="TVR04_001000"
     CDS             21838..22620
                     /gene="codY"
                     /locus_tag="TVR04_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1269701.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PVESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            23250..23807
                     /locus_tag="TVR04_001001"
     CDS             23250..23807
                     /locus_tag="TVR04_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1269702.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASTAEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     SRENHQWALNHCRTVLGAKLLDQLS"
     gene            24241..24543
                     /gene="gatC"
                     /locus_tag="TVR04_001002"
     CDS             24241..24543
                     /gene="gatC"
                     /locus_tag="TVR04_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1269703.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGIAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            24543..26009
                     /gene="gatA"
                     /locus_tag="TVR04_001003"
     CDS             24543..26009
                     /gene="gatA"
                     /locus_tag="TVR04_001003"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1269704.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIAEEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIIIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTSKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFKLDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQAAAAFEATTDYHKQQPMIFGGDS"
     gene            26009..27448
                     /gene="gatB"
                     /locus_tag="TVR04_001004"
     CDS             26009..27448
                     /gene="gatB"
                     /locus_tag="TVR04_001004"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1269705.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGTADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPAERRVSYIKDLGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIDQLALTPDSLVEMIAIIADGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            27677..28621
                     /locus_tag="TVR04_001005"
     CDS             27677..28621
                     /locus_tag="TVR04_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1269706.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSSMAYMRQRDAVIRLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIAAWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVFFAIILMKETFHPIDL
                     LGMALILIAVLVISLRDLLLAQRKKQLALKAKRLPSSD"
     gene            28672..28911
                     /locus_tag="TVR04_001006"
     CDS             28672..28911
                     /locus_tag="TVR04_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1269707.1"
                     /translation="MIWSLIVGAIIGMIAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
BASE COUNT         7824 a         5733 c         6999 g         8424 t
ORIGIN      
        1 ttcgagataa gttccggagg tcatatatgt aaaaatgtaa ttggaggatg tagcaaatct
       61 aaaggtaagc atatttttct ttacgaaact ttgagtgatg gaaaagacaa aaaaggtata
      121 ataaaaataa aacaaactga aaacttaaac acttatattt ctgatatcga aaaattatta
      181 tcagaaaatc cattgtcaga taatagcaag caacttattt gcagtaaact aagaaaagcg
      241 gttgagtttg ctattgatga aataatttta aatagacagg tacctactaa atatagcaat
      301 aaaaacagtc gaatccattg ggatgaatta aagaaaattg acaataatcc tattacaatt
      361 gaaaaactcc ataatattca tgggcggtgt tcaggagggg cattgcataa tggaactgag
      421 agtgaagaga acccagttga taaagacgag ctggcaaata tgctgcggga aatccagact
      481 atacagacta gccatcgata aattcattag tgattgaaag aatatgtaaa ataaagagga
      541 caatatatca tttaatgtcc tctttatttt ccgccgaaag attttagacc ttcctaatat
      601 tattttgata ggtttaccca cattatctaa aagagattgt tatttttaac ctgctatacg
      661 tcaagctacc tttgcagggc tgtttttttc tttgctttat tgtgaaaaaa atctcaaatt
      721 caatcttgac aaaggcttga caacatgata aattaagtga gattaataaa ataattaaat
      781 ggctaataac atttttagaa ggtttgaaat aatgaaaagt atcaataagt gcgccattct
      841 tgctttatca acgctggctc ttgcccagtc tgcccagacg gttcgctcag aggctactca
      901 agtctcttca agtcttgtga cgactgtcaa gcttaaggat aatattttat tgttcgagga
      961 gatcggtccc tatgcggaca agtcagaggg gaagctctat tataaaaata tcgagaaaat
     1021 tctcattgat ggtaaagagt atgacaaaaa gctggagggt gactatagct atgacatcaa
     1081 ttaccaagga atcaaggtaa acgctaagaa catcacagaa ggacagcatc agctgcgcat
     1141 cgtcaataag actaacggag gcattcttgt ggtctttgac aagaaaggaa atgatgtcac
     1201 ctttgtttct gccaagcctt cagatgatac tactgcttca ccgcaacaag ctactgctaa
     1261 gacagaaaag cctgctaagg taactagcta tgatggctta gcgaccctat catttatcac
     1321 caaactagag gcaacagaag gggagcttct ttttccggaa attgatcgct attccagcac
     1381 caagcaaatt aaggaattag ctcatcaaat cacaaagatc aaggtcaatg accaggacta
     1441 taaggatttg gtctatgatt cagtaaagga caagcctggc tatgtgtctg acctgaaggg
     1501 gcttcatctt gggacgacag ctttcaagga gggagaaaac aaggttgtca tttcctcaca
     1561 aagctttgaa gatgtcatca ttacagtgaa aaagtcaggg gagcaataca cctttgtttc
     1621 tgctaagcaa aagcagggac aaggatccca gcaggaagca ccgcagggac ttgattttac
     1681 taagctggaa agcgcgatca aggaagctga gcgtctcatt gctagcgagg ccaataaaga
     1741 acaggtcaag gacttgtcta gcaagcttca ggtgatcaag gaatcatatc atcatattga
     1801 taacgagacc ttgcttaagg agacctatga gcttttgatg gatagtatca aggcctatca
     1861 gggaactgat ctggctgtta cggatctaaa ggcaggaacc tataccttaa cctttaaggc
     1921 caataaggaa aatacagagg aagcctcaat gctgcaggga gcatttgata agaaggccaa
     1981 gctggtcgtc aaagaagatg gcaagatgga gatttcattg ctcaatacag ctctagggca
     2041 atttttgatt gacttttcca ttgagagtaa agggcagtat ccaacctctg tccgcactca
     2101 ggttggtgaa cgcgatatta acaataacta cattagaagt gaatttaccc taccgattga
     2161 ggagctggac aagcttcaca agggtgctgt gctagtatca gctatgggtg gtcaggaaag
     2221 cgacctgcat cattatgata aatatactaa gctagatatg acctttagcg ctactgcaag
     2281 taaggggtgg acaggctatc aggctgagat tgacgacaag gaaaaaggaa ttggctctga
     2341 gcgccttgaa aaggttttgg ttaagcttgg taaggacctt aacggtgatg gcaaaatgtc
     2401 acctgaggaa atcgcaaaga ttgaaggtga gctgcgccta gaccactatg atttgacaga
     2461 tatttcactc ttaaagcatg ctaagcatat tactgagctg cacttagagg gcaatcagat
     2521 tgcaagcatt ccaaaggaaa ccttcagtca aatgaccaat ctcaggttct taaatcttcg
     2581 cagcaatgtg attacaaccc tagataagga tacctttgct cataacagcc agctaaaaga
     2641 gctctatctc tcaagcaact atatgccaaa tctggaggaa ggactattta gaaatcttgg
     2701 tcagctggat cagctagacc tgtcaaaaaa tagaatcagc gtgattcgag atggtgtctt
     2761 taatggtcta tctcgcttga cctccttggc cttggctgaa aatatcatta ctgatttttc
     2821 agaaaatgct ctagcttcac ttgataatct aaacttcttt gatgtttctg aaaaccagtt
     2881 gggcagcctg ccaagctcct tgagtaagct aactaagctt tcttatatcg ttgccaatcg
     2941 aaaccagatt ttagatattg ctaatattga ctttagtcat atgccaaact tattaaccgt
     3001 tgacttggca tcaaatgagc taactaaaat cccacaggga gccttcaagg ctaataagca
     3061 gctatcaaag cttaatgtct ataataatct tttagctaat attagcgagg ctgattttgc
     3121 agatctaaag gcacttgatc ttgaccttaa gtttaattgc ctaagtggcg ttagtgataa
     3181 gcttagacag ctcatgggga caaataagct aaacccacaa aagcagctgg ctaatctgtc
     3241 tgcggcctta aatcaccaag caattaccta tcatcaaggg tttagcctgc ttgatttgta
     3301 ctattgggag cagcagacac tctcaagcac tgaagcagaa attagctcta tcgaggatta
     3361 caataaacgc cttaaggcaa gctcgtcaga catcattgcc ttattaaatg agcgttatgc
     3421 tgactgggat attgtggtgc aattgcagaa aaaaacatca accggtcaat atgtcaccgt
     3481 tgatgagaga cgcttgaata acgatccaca agatgagctt caaggctcct ttgacctaaa
     3541 gggagcaggt gtttatcgtg ttcgtaaggc tcttatcacc aaggaatttg ctaagaagcg
     3601 tgagcatatt tatctgacct ctaatgatgt tgaggtcaag gaggatcagc ttgcaggtag
     3661 tggccagtct aagggcttgg atattaataa gcttgaagat ggtatctact atatcaaggc
     3721 aagcatgctt aaaaatgatt tgcagtcaga atcaatgtct catcaggcta ttgaccaccg
     3781 cgtcaaattg attgtgaata agggtgtcta tagcctagag gtgaccttta agggcatgaa
     3841 gatcggtaac ctgacagggt atctcggaga gttgagctac tttgttgatg gctaccaaag
     3901 ggatttgact ggcagaccgg ttggtaagac agaaaaagca gaggttgtgt cctactttac
     3961 agatgtcaca ggcaagcccc tgtcagacgc ttatggcagc aattacccac aggtgttgag
     4021 atttagactg attgatcagg ctaaaaagga tggcttggta cctcttcgcg tctttgtgcc
     4081 aattatggac gctatctcta agggaacagg cttccagaca gtctttatga agttggatct
     4141 tcaaagcctg acaaaggata aggcacaatt gccacactca gaggacaatc agggacatgg
     4201 taccataggt gagctcttgc agcctcacac aggtatcatt ggtggtcata caagtcctgc
     4261 tattcctaat ttgaccaatc ttttggctaa gaagtcagct gctccaagca gtaatgccaa
     4321 ggaggacgct aagaccggta cagataagct taagagcctg atttcttcac ataaggcgtc
     4381 taaggctggt acaggcaagg cctctaagca ggctgctaag actagagcca aagctaaatc
     4441 taaggctgct aaacatagtc aggagcagat gaaagctgat catcgcggcc atatcattat
     4501 cggtctagca agctttattg tcatagcagt tggtctcatt cttggtagga aaaaattatt
     4561 ttaagtcagt agagagtctg tttgatgcac taagagcttg gtttaatcgc ttgtagtcat
     4621 caaggcttat caacgatacg taaaggcatg cctgtttcta atgatttctt aagcttaccc
     4681 ttggtaagtg aggaatgggt atgcttttcg tatttgaggt gttataatag tcaaataaga
     4741 gtaggtcttg gcctgcgtct aaatctatgc cttatttgat tgtcgtaagg aaatgaagat
     4801 cattaatgag gaacatatga taaagagatt attcaaaaaa ttaataggtg gcttggtgat
     4861 attgctggtt tgcctagcag ctataggagg taaggcctat gctgataagg gtgagcttta
     4921 ttcctgtgtg attaggcgag attatcgcca cccagtttca gggcagattg aagatagcgg
     4981 tggtgagcac gcttttgaga ttggccaagg catggtggaa ggaacagtct atagcaatgg
     5041 tatgctagag gtaacctcgg ctggggattt gtatctgacc tttcgcatga gtctagctga
     5101 tttttcaggt aactaccaat tttgggttca gccgggtggt acaggggctt ttcaggcggc
     5161 agcctacaat gtgactaagg ttggcactga taccaatggc acaacaaagg atattgcgat
     5221 tgctttgcct gatgtcaata cggttgttag aggcagcatg tacgtagagc ctatgggcag
     5281 agaggttgtc ttttaccttt caccctctga tctacaagaa ggctacagtg gagatatggt
     5341 agctagcttt gcagcaggag aagccaagac ggatcatgcg gtgacagctc cagcaaaggc
     5401 agatgagaag aaagctccta gtaaaccgga ctcaaaagac gccaagtcag ctcctaatcc
     5461 ctcagcaaga ccagttggtc aatcaagcac tctaaaaaaa cagtcaagtc cctctaagaa
     5521 gggtcaggca gctggcttaa ccacttcgct agataaaagt aagccagagt cgtcccaaaa
     5581 accagtaaac aatccattgt cagttctggt ttattatgta ccaacagctc ttctgctgtc
     5641 aggagctttg gtcttgttta taaagaaaaa gagaaaaaac aatgaagaaa gtcattaagc
     5701 ttatcggatt agctgttttg tccttggcgc tatctgcttg tgtggatcag caccctaagg
     5761 cagagaaaaa ggctgataag gagagaatcg ttgccacctc tgtggctgtt gttgatattt
     5821 gtgatcggct aagcctagat ttggttgggg tctgtgacag taagctgtac caattgccaa
     5881 agcgttacga tgctgtcaaa aggatcggtc tgccgatgaa tcctgatatg gagattattg
     5941 cttctctaaa gccaacgtgg atacttagtc ccaattctct gcaaaatgat ttagagccta
     6001 aataccagca attggatacg gaatatggct ttttgaattt aactagcctt gaaggcatgt
     6061 accagtcgat tgatgatttg ggggacttgt ttgatcgcaa aaaggaagct aagcgcttgc
     6121 gggctgatta tgaggagttt taccaggcct ttaagaaaca gcataaaggg caaaaaaagc
     6181 ctaaggttct tattttgatg gggcttcctg gcagctatct gattgctaca aacaaatcct
     6241 atgttggcaa tctgcttgag ctggctggtg gtgagaatgt ttatcattct gaagacaagg
     6301 aatttttgtc tgccaatcca gaagacatgc ttcagcagca gcctgagctg attttgcgta
     6361 ctgcccatgc tattccagac aaggttaagg acatgtttga taaggaattt gctgaaaatg
     6421 atatttggca gcattttgaa gctgtcaagt ctcagcaggt ttatgattta gacaataccc
     6481 tttttggcat gagtgctaag tttaactaca aagaggcttt gaatcatctg tcacaaatct
     6541 tttatggagc aaaggaagtc aactaagatg cagcaaggta gtcaatattc tgatcaagtc
     6601 acagcagcaa gaaaaagaac cactagacta gtttatatgc ttctattgct catgctgctg
     6661 tttggcttaa tgctatatgc ggtctctgtt gggggcttat ctgtttctta tcagaggata
     6721 tttagcggct tatttgtagc atatgatcca gaggtagccc ttatttatga tttacgcttt
     6781 ccaaggattg tgattgcttt actggctggg gcgggtatat caacatctgg agtcctgttt
     6841 caggcgattt taaaaaatcc tatttcagat ccggcgatta ttggggtttg cagtggggct
     6901 agctttatgg tcttgttatc tagcctgctt ttgccgcagc tcttgtttta tggtcctttg
     6961 ttatcatttg tgggaggctg tgtttctttt ttgatgattt ataccttgtc ttggaagaag
     7021 ggcttgcagc cgatacgcat cattttgaca ggaatagcta tcaacgcctt gtttttaggc
     7081 ttgtctcgtg cgattactga tttttcaaaa accagcaatc cctttgtcaa tgcgctgttg
     7141 tcaggaaata ttagtcaaaa aacctgggca gatgtcggtg tgctgtggcc ttatacagtg
     7201 cttggcctgc tgcttgcgat aggtctagca aggcagtgtg atttgttgct gctaaacgat
     7261 ggtttgattc gtaatttagg cattgatagt aattacctgc gcttaggaat ctcactggta
     7321 gcggtcttac tggctgctgt ttctacctca attgtgggtg tggtgtcatt tttaggcctg
     7381 attgtgccgc atattggccg ccttttagtt ggtagtaagc acagctatct cattcctttt
     7441 tctgccctgc ttggcgcctt tgtctttttg ctggcagata ccttaggaag acaattgtgt
     7501 tatcccttgg agattagccc agctgttatc atgagcattg tcgggggacc ttattttatt
     7561 tatctgttaa ggaggtctga tctgatatga ggcatgagca agacttgatt agtgtagagg
     7621 atttgtcctt tacttatcgt gataggctta ttttagatag gctgagcttt actattccaa
     7681 aaggcaagat aacgacaatc atgggggcaa atggctgtgg caaatcaacc ctactggggt
     7741 tgctgactaa aaatatcccc gttaagtctg ggcagatttt cctagaggga caagctgtta
     7801 gctccattag tcttaagcag tttgccaaaa aagtagctgt tgtgcatcag gataatcagg
     7861 cggtagcaga tcttctggtg ggtgatttgg tggctatggc aagacaagcc catcggcgtt
     7921 tttttaaggg accaagtcaa gaggacgatg acattgttgc ttgggcctta gaggtgacta
     7981 atctaaggga attggccttt agggaaatgc aggagctatc tggtggtgaa aagcaaaggg
     8041 tctggattgc tatggcgctt gcccaaaaaa caggtgtctt agtgcttgat gagccaacca
     8101 cttatcttga tattaagtac cagctggaca ttttaaccct catcaaaaaa atcaatcagg
     8161 agctaggaat gaccattatc atggtgttac atgatattaa tcaagccttg gctgtttcgg
     8221 attgtgtgct tgggctgcaa aagggtgcca tttatgctca gggcagtcca caggagattc
     8281 ttgatcaggc ttttgtggag gcagtttttg gggtgagctt gccctttatt gaaaagcagg
     8341 ataggcgatt tgtccttact actttatgaa acaaagaaaa aatgaatgat agataggaat
     8401 aaggcgacga ttatatgaat gatacaactg aaaaaatatc acgcgcaaag aaaaaaatgc
     8461 ttttaaggcg tttaaaggag cgtattgctc ctaagcgttt tttgctttat gtgtcggcct
     8521 ttttatcttg gctgcaattt ttgatgcgtt taatgagctt ttacttaatt gctaagcaat
     8581 tcacagcctt tttagcaggt caagccctgc aattgacaag gctgcttgtt atccttttga
     8641 ttttaaatgc tgttggcttt ggcttggcaa tgattgcaaa gcagctgcag ggcctagctt
     8701 cgcaatttgc gcgtgactcg ctcaagcaat ccttttttga tgcctttatt gctatggacg
     8761 ggcaatttga tcagcagtca acagtggctg atgtgttaac ggttgcctca caagggattg
     8821 atagcttgga tacctattat tcctattacc tatcgcttgc aatgcgaaca gcttttaatt
     8881 gcacaacggt cttactgctt gtttttttga tctatcctat agggggcttg gtctttatct
     8941 tgtctttgcc cttgattccc atatccattg ttgctatgca aaaacgctct aaaaggatca
     9001 tgaaccatta ctggtcaacc tatatggacg ttggcaatct atttatggac gatctcaagg
     9061 ggctaaatac cctttattcc tatcaggcag ataaaaggta cgaggaaagc tttgtggcaa
     9121 aggctgaggc ctttcggaga gccaccatgc agcttttagg cttccagcta caggcggttg
     9181 gttatatgga cgctgtgatg tatcttggca ttggcttatc tggcttttta gcggttcagg
     9241 ctctgtcagc tggcggtata tccttttttg attttctctt ttttatcctg attgcaacgg
     9301 aattttttgc ccctattaga gaacagggct atgggatgca tttagtcatg atgaatacca
     9361 aaatggcaga tcaaatcttt ggctttttag acagtgttga ggctgttgac caaggcaagg
     9421 gagttgcctt accggccttt gatcgtattg atattcaaga tttgtccttt tcacatgggg
     9481 aaaaggcttt gctaagagac atcacgatga ctatcaaaaa gggtgagcta acagctgttg
     9541 caggtgtttc cggacagggt aagactagtc ttgcacagct cctgttgaag cgctatcagg
     9601 cagatagcgg tcagatattc cttggtgatg tagcgattga tctggcttct aaacaggcca
     9661 tcaatcagga aatactctac gtttctgacc agtcaacatt gcttaatatg agtatttatg
     9721 agaaccttgc tatagcaact caactgacaa gaaaggagct gcttagctgg attgatgagc
     9781 atggcatttt gagctttatt tactggctgc ctgatgggat tgataccatt gtaggtgaga
     9841 atggctgtca cttatctgca gggcaaagac agcaggtgat ttgtgctagg gccttgttga
     9901 gccagcgttc ctgttatatt tttgatgagg ctacctcaag tcttgatgct gagaatgagg
     9961 ctgccattca tagactgctt cagcaattgg ctaaaaaggc cattgtaatt gtcatcactc
    10021 ataagatgaa atatttgaag caggctgatc aggtgctctt tttaagccct gagcagtctg
    10081 ctagcttggc tagcccaaga gagctttacc gacaccattt ggcctatcgt caattagttg
    10141 atacacaagc agaattggag gcaaatcttt atggttaaga atgattacag cacctaccag
    10201 cttgttttac gcttacttgc tatgatgaag catttactag tctggatagc tctggcagtt
    10261 gtgtttgcgg tgttaggctt tatgcttacg gtcagcattc ctactagctt agcctatctg
    10321 ggattagagg tgatggcagg ccatgctata gcccttaaat ggctttatct atttattgcg
    10381 ctggcactgc taagaggact gtttcgttat ggagagcatt attttggaca ttttgttgcc
    10441 tttcatagct tagcagcctt tcgcaggatt gtctttaaaa agctaagggc actctcgcct
    10501 gctcgcttag atagtcaaga cagtgggcac ctcttaaaga tgattggcga ggatattgag
    10561 gccttggagg tcttttttgc ccacacgctt gcccctattt gtacggcgtt tatttcagct
    10621 agcttgatgg cctattacct ttggcaggtt agctggaagt tagccttggg ggctattgtg
    10681 acctatgtgc ttttggctgt catcattcca gtatattttt caaatgtcct tcaatcactg
    10741 ctcaaaaagc aaaatgaagg gcgcaggact tatgtgtcaa gctttttaga gagcctcagg
    10801 tctgtcaagg atttgctgca atttcaaagc attgagaagc gctttaagct cttatccaat
    10861 caaagcaagc atgttaatgc gcttgatcgt caggtggcac aggctcaatt tttgcaaatg
    10921 gcgataacct ttttggctct tggcttgtct attttgacct ttgcttatgt tacccttttt
    10981 gagctgagtc agcagacggt gacgtttgct ggtgggctgc tggcttttgt tgcctttaca
    11041 gcctcttttg cccccttttt agaattgggg cgtttgccgc ttggcttcaa gcgtgccatg
    11101 aatgctgcta ggaatgtctt tcagctttta gatgaagaag cgttagtaga taagggagat
    11161 cagcgtattt cctcggtaac aaggattgct gttgaggatc tgacctttgc ttatcccaag
    11221 catcaggaga ctatttacca ccacttatcc gtcgcttttg aaaagaaagg cattatcggt
    11281 attcagggag agtcaggctc tgggaagtca accctgatga aggttattat gaaatggtac
    11341 agctggcaag ctggtcatat tttcctgagt gaggtcgaca gtcaactgtt aaatgctgct
    11401 tccctacagg ctaactttgc ctatgtccca cagaatgcgc agctatttca gcaaacactt
    11461 cgtgacaata tcacacttgg tcgtaaggac atttcagatg atgatatcat ggagcttgct
    11521 gaggcctgcg gcatgaagga gcgtatccta gcttgtgctg agggcttaga caccctagtg
    11581 acaggctcag cagacttttc agctggtgaa gcccagcgcc tggaattgat gcgggctcta
    11641 ttgaagcggg tggattgcta tatttttgat gagccaacat caaacttaga ttcgctgaat
    11701 gaagccatct ttattgattt gattaaaaag cattgccggg gaatggtctt tttgatttca
    11761 caccggccgt ctaccttggc ctgtgcagac cagctatttt gtgtgagaaa tggttttttg
    11821 aaggaggtaa acaatgaaag ggttaaccat taaagatatc atgacaacag gcgcctttgc
    11881 cgccctctat ttcgtttgtg tggggctagg agccatgctg agcattctgt ttgatcgctc
    11941 aggcaatatg ctctatgcgc cagcctttgc ggccttgctt ggcgggcctg tttatatgct
    12001 attaatcgct aagctgcaga tctttggacc gataagccta gtaggaatta ttatgggaag
    12061 ctttttcttt ttgacgggtc acttttttgc ttcaatgctg ccagctattc tttttggctg
    12121 tttggcagat ggcatagccc ttttagggaa atatcactct aggctggtga atctcttgtc
    12181 ttattttgtc tttgcctttg ttaacagtgg tcctattatc ttaatgtggc tattgaagga
    12241 cgcctatatc aagagtcttt tagcgcgtgg taaggacatg gcatatgtta accgtatcat
    12301 gtatgacttt accgttgcaa atgtcagctg gtttgttggt gttgtccttc tttgtgcctt
    12361 tgtaggtggc ctttttggtc aatacttgct gaaaaagcat tttgctaagt caggaatgct
    12421 tttatgaggc ttgatgttcg cacaaaattg ctcctgttaa ttctagccaa tgcctgcttc
    12481 ttttttcgga ttgatggctg gctggggacg atgattatag gcattttgct tggtattttg
    12541 ttttggcttg gtcaagggcg tctggcaatc ggtatgacac tgctctatgc gctgctactt
    12601 ggtttgcctg tgctgccgct tcatagtagc ctgccggctt atctgtttag tcagctgagc
    12661 tttgtagctg ttgctggtca attgctttac ccatctgtgc ttgctgcctt gatttttgtc
    12721 aagacaacga ctgcctacga gcttgtgcat gggctgcgaa aatggcatgt accagaggtt
    12781 tgtctgttga ctcttgctgt catgctgcgt tttttaccta agatcaggca agaaggaaag
    12841 attattcggc aatctctgaa aatcaggggc attttcttgg acagctgggc tattgtcaga
    12901 cagccgaggc ggtatatgga gtatctcttg gtaccgctat taatgtcact gctgagaagc
    12961 agtcaggact taactattgc tagcctaaca aaagggctgg caatcaaaaa gggagcaagt
    13021 gagtgcttcg tatcacatct atcatggaag gattgggggg tacagatttg gatacttgca
    13081 acgataattt acatggttct ccagtgatca aggcaaagca gctgaagttt tcctatacca
    13141 atcgtaggca gactgcctgt gagcttaggg attgtcaggt agaggcaggt caatttattg
    13201 tgctttgtgg tcaatcaggc tcaggcaagt caacctttct taagctgctc aatggcttga
    13261 ttccagacta tttttcaggg caattacaag gaagcctgag agtgctgtcc catcaggctg
    13321 gtcaggctag tgttgaagtg ctgtcaaggc aggtttcctc tgtctttcaa aacccagcca
    13381 gtcaattttt ctatcgtgag gtcaagcatg agcttgtttt tccttgtgaa aatcaaggct
    13441 tagagccagc tcttatcctt gagaggctgg ataccttggc agctgatttt gacatcaagg
    13501 acttactaga agcagatatg cttaagctat ctggtggtca aaagcagcgg gtggctattg
    13561 cagcagctat catgcaaggg acagctatca tggtttttga tgagccaaca gccaatttgg
    13621 accatgctgg tgtagcagca gtcaaggcct atctaaagca gcttaaggct gctggcaaaa
    13681 ccattattgt cgctgagcac cgattgcatt atttgctgga tttggcagac catttttact
    13741 atttttcagc tggtaggcta gagcacgtat taagctccaa ggatctgcta gctttgccag
    13801 atcaggagcg tgaggagcta ggactaagac gatgtgagtt gactgctgtg accaaggctt
    13861 tgcgggcaaa aactgttttt gagcattatg atccagagca tgccctgcaa atcaagaagc
    13921 tagaggtcag ggcaggcagc agggttttgt atcacctcaa tcagctcagc tttggtgcag
    13981 ggcaaatcac tggcattacc ggagctaatg ggctgggaaa atcacagctg gctttatatc
    14041 tggcaggtat ttttgaagca aaagaggcca aaatcagcta tctgggcgtc cctctgtctg
    14101 ctaaggacag gctttcaatc acaagcctag tgctacagga cgttgggcta cagctatttg
    14161 cagagacggt agcaaaggag cttaatctgg gtcatcatag acatcaggct actgatgatc
    14221 tggtgaatag gcttgggctt tctcagcttc tagacaagca ccctgccagc ctgtcaggtg
    14281 gtgagcagca aagggtgatg attgctgcca gcctcttgtc tgacaaggag attgtcattc
    14341 ttgatgagcc aagcagtggc ttagatttgc tgcaaatgca ggccttagtt aatctcttaa
    14401 aggagctgaa gcagcaaaaa aaggtagtaa ttgtcatctc tcatgacgag gaattactgg
    14461 atcaagcctg tgatagtatc tatcagctgg gcaggtaaag gccctagcct tgctcaagtg
    14521 atctggtgct gtattggtga tggcttcatc gttccttgga gcagcaggtg ttcctgcttg
    14581 atctgataac cagtagctgc gattgaccaa tcacaagcct gagcctcttt tagccaactc
    14641 tagacaagct agcaatagct gtcacaatgc cagggtagat ctttgcctag taaataatgc
    14701 tgtgctgtct atatgccact cttcatcttt tagttaggcc gtcctagcgg ccgcactaag
    14761 ggtgtgttag gatcggctaa tatctcaagg cacctacaat aagaaaacga gcctcttcct
    14821 ttttggagag gctcttgatt tttgatataa taatgaaaaa gaaagcgagg ttgagatgct
    14881 gttaaagagt tcaattgcta atttgaaggg gcttggtcca aagtcagctg agaaatttca
    14941 aaaattaggc atttatcaga tcaaggactt gctgctctat tatccttttc gctatgagga
    15001 ttttaagagc aagtcagcct tagagctttt agatggtgaa aaggctgtcc ttacaggtag
    15061 agttgtgacc ccaccaagcg ttcaatacta tgggttcaag cgtaatcgcc tgagctttaa
    15121 attgaagcag ggggagcttg tgattagcgt cagctttttc aatcagcctt acctacttga
    15181 gaaaatcgtc ttggatcagg aagtggctat ctttggcagg tgggatcaaa aaaaagcagc
    15241 cttgacaggt atgaaattgc tcatgacctt agaagatgat ttgcagccag tttatcatgt
    15301 ggcgcagggg atcagtcaac caaccctgat taaggcgatc agatcagcct ttgatagtgg
    15361 tgccttagct cagctggaag aaaatttacc agagcccttg attcagaaat accgcctgct
    15421 gccgagacaa gctgctgttt atgccatgca ttttcctaaa catatggagg attataagca
    15481 ggccttgcgc cgtataaaat ttgaagaatt tttctatttt cagatgaatc tgcaggtttt
    15541 aaagcttgct aacaaggcag agggcaatgg gttagcgatt ccttttcatc agcaggcagt
    15601 ggcaaaaaag attgctgctt tgcccttttc actgaccaga gctcaacaaa gaagcctgga
    15661 ggaaatctta gcagatatga cctcaggggc tcatatgaac cgtctgttgc agggggatgt
    15721 cggctctggc aagacagtga tcgcaagcat tgccatgtat gctgcccaaa cagcgggatt
    15781 tcaatcggca ctcatggtgc caactgagat tttagctgag cagcattacg atagcctttg
    15841 tcagctgttt ccggatttgt ctattgctct attgacatcg ggtatgaaag cagctgaaaa
    15901 aagagcagct ttatcagcta ttgctgatgg gtctgtagat atgattgttg ggacacatgc
    15961 cttgatccag gatacagtaa cctatcataa gctagggcta gtgattactg atgagcagca
    16021 ccgctttggg gtcaatcagc gtcgcttgtt tcgcgaaaaa ggcaacaatc cagatgttct
    16081 gatgatgaca gcaactccca tacctagaac cctagccata accgcctatg gtgagatgga
    16141 cgtttccatt attgatgaat taccggcagg gcgaaagcca atcatcactc gctgggtcaa
    16201 gcatcagcaa ttagatagtg tgctggcctg ggtaaagacc gagcttgcta agggggcaca
    16261 ggcctatgtt atctctccct taatcgaaga atctgaaact ctggatttga aaaatgcggt
    16321 agctttagag gctgaattga aggattattt taaagcttca gctagcattg ccttgatgca
    16381 tggcaaaatg aaggcagacg acaaggagat gatcatgcag cgctttaagg ctaaggagat
    16441 tgatgtcttg gtgtcaacaa ccgtcattga ggttggggtc aatgtgccaa acgctaccat
    16501 catgctgatc atgaatgctg accgctttgg tcttagccaa ttgcatcagc tgcgcggtcg
    16561 tgttgggcga ggcagcaagc aatcctatgc tattttggtg gcagatccta agacagactc
    16621 aggcaaggag cgtatgacca tcatgacaac gactaatgat ggctttgtgc tggcagaggc
    16681 tgacctcaag ctgcgtggct caggagagat ttttgggacc cgtcaatcag gtttaccaga
    16741 gttcaaaaca gctgatattg tagaggatta tcatatccta gaggaggcaa gacgagtagc
    16801 tactgagatt gttgcagcta agaattggca gctagaccct agatgggctc cgattttggc
    16861 taatcttcgt gtcgctgatc agtttgatta gatgtgaggc tgacttgctg gacagagcta
    16921 atataaaaac acgacaagag gttcttagct gaccgagtcg tgctttttgc gctatagatg
    16981 agaagtagta gccttgcgat tatggcagag cttagccttc gatataatcc ttcagctctt
    17041 gacctgtaag cccagcgttg agggcgatga gcaattttaa tctggcctta ggggcattta
    17101 gctccttgac aaacatgaca ccagcccttt ttaagctggc accccctccg caataagcat
    17161 aaactggctc tgctatgcca ttgaagcagc gcgagaccaa gacaacagga atcccagagg
    17221 cgattaattt ttcgagttca gatactgcta ggggaggaac atttccagcg ccgagggctt
    17281 caatcactag tccctgaatc ctatcaggtg tcaaaaggct taaaatactt ccatctccca
    17341 taccagcata ggccttgata atcggaactg ttccagaaat atgacgaagc tcaaagcgaa
    17401 cccttggctc agcagtctta aagaacagta aatcgtcctt catgacgatt cctaaagggc
    17461 catgagtcgg tgtttgaaag gtcgaaacat tggtggtatg tgttttggtg acatacttag
    17521 cagcatgaat ctcatcattc atcacaacca gcaccccctt gcccttggct ttctcatggc
    17581 tggctaccct aagtgctgtt aggtagttat agataccatc gcttccaatc tcgttggccg
    17641 agcgcatagc acctgtgata acaataggca gctctacagg cagcaccatc gtgtctagaa
    17701 aataagcagt ctcttctaag gtatctgtac catgtgtgat gaccactgca tcaaactgac
    17761 tagccctttg ttgaatgtaa tgatacatct tgagcatgtg gtgaggggtg atgtgtgggc
    17821 ttggcagatt taaaaaatcc acaacagtta agtggatatg ctccaggcta aggccaacct
    17881 gattcattgg attactttga tttgggctca ccttgcctgt ttcatcggcc tgcattgaaa
    17941 tagtgccgcc ggtatgtaag acgaggattt ctttcatttg atactcatac ttctttcaat
    18001 ttgtgatata atttattcta tcacaaatag aagagagaac agaaggattt gacaataaaa
    18061 gcagtctttt tcgacattga tggtaccctg cttaatgatc gaaaaaatgt tcaaaaaacg
    18121 acgcaaaagg ctattcagca attaaaaaaa caaggtatta tggttgggct ggcaactggt
    18181 cgtggacctg cttttgtgca gcccttttta gaaaattttg gcttggattt tgcagtgacc
    18241 tataatgggc aatacatttt atcgcgtgat aaggtcttgt atcagaacca actgccaaag
    18301 tcaaccattt ataaaatcat tcgctatgct agcgacaaaa agcgtgagat ttccctagga
    18361 acagcttcag gtcttgctgg gtctcggatt attgatatgg ggaccagtcc atttggccaa
    18421 atgatcagca gtattgtgcc aagaagtctg gttaagacgg ttgagggcag ctttaaaaat
    18481 ctcatcaggc gctttaagcc gcaaagcttc agcaatcttg ttaccattat gagagagccc
    18541 atttatcaga ttgtcttggt tgcttctgtt gatgataccc aaaaaatcaa ggaaaaattt
    18601 ccgcatatca aggtaaccag aagcagccct tattccttag atttgatttc tagcgggcag
    18661 tctaaaatca agggcattga acgcttgggc gagatgtttg gctttgagct ctcagaggtc
    18721 atggcctttg gagactctga caatgactta gaaatgctct caggcgttgg tgtcggtgtt
    18781 gcgatgggaa atgccgaggc agtggttaaa agcggcgctc actttacaac agcttcaaat
    18841 aacaatgatg ggatctctaa ggcgctagcg cattatggct tgattcattt tgatgtggaa
    18901 aaaagcttta aaagtcgcga tgacaatttc aataaggtca aggatttcca ccgtctaatg
    18961 gacggagaca cgattgaaac accaagaggc tattccttaa aggaggctgg ctatcgagcg
    19021 gatttcaagg ttgaggagct tgtggaattt ctttatgcag ccagtcaagg ggataagcat
    19081 cgtttttctc aggctttgat agacctccat gctgcccttg ataaggcagc taagaaggtg
    19141 caggccaagg agcacccaga gtcacccctg gttgggcagg ttgatgcttt gacagatctg
    19201 ctttatttta cctatggctc atttgtattg atgggagtgg accctcagcc catttttgag
    19261 accgtccatg aagccaatat ggggaaaatt ttccctgatg ggaaagcgca ttttgatccc
    19321 ataacgcata aaattcaaaa gccagatgac tggcaggagc gctatgcacc agaatcagcc
    19381 atcaaaaaag agttggacaa gcagctccaa aaatcattgc agcgcttgga aaaataggat
    19441 tgtctttatt ttagaaagcg ctaaaaagca ccttgagctg tgagttgatc tcctagctgt
    19501 tagcatttgg cctaacgctt ggggtcactt cacttattag ctcagggtgc tttttgatgt
    19561 agactagaca ccctcaataa aagggccctt aaagtctagc tagtggtaat tagtatatga
    19621 gagcagtagt cctttagcag ccttgtgagc tgaggctaag ggctaggtat ggttacttca
    19681 cttaggctgc aaatgcttct gacagctgag agagttcgtc ttgctacagg gttttgtcat
    19741 gctctcggac cactaatagg tcaaccttag catgacgaag gatatattca gatgatgatc
    19801 caataagcaa ccgctcaaag gtgttcagac cagttgcgcc aaccataatc aagtctatct
    19861 tttctttgtc aggaatatcg tgagccagca aggttttggg attgccaaat tcaatcacct
    19921 gcttgacctc agtcagccct gcctcgcgtg cctgcttttc aaagctgctc aagacctcct
    19981 tggcctcctg ctccaacttg tcataaatgt agctatcaaa ggttgcaacg ctttgcagcg
    20041 cacgtgtatc aacaacatgg gtcaaaatca aggtagcacc attacgcaag gcgacattaa
    20101 cccccttgtg aaaggctaat tcggagccat gagagccatc aatagcgacc atgatacgtt
    20161 catatgtttg tgacatcggt ttatcctcct ttgaacttta tctctatagc tattatacct
    20221 tttttgagga gaaattgaaa acgttttaat gattttctga gctgttgttc accaaatagc
    20281 ccagctattc cctgaggtga ggatatcttg agctagaagc tagcttagat agccttatta
    20341 atagctgctg cttagcttgc ttagagcttt tggcgctctt taagctaata gaaaagtgct
    20401 ttctatttta attgttttgg tttataatat gggttacgag gtaatgagac tatgaaaata
    20461 attgaaaaat catcaaaatt agaacacgta gcctacgata ttcgaggtcc agtcttggac
    20521 gaggctaatc gtatgatagc taatggtgaa aagatccttc gattaaatac aggtaacccg
    20581 gcagcctttg gctttgaggc tccagatgag gttattcgtg atttgatcct caatgctcgc
    20641 tctagcgagg gctattctga tagcaagggg attttttcag cccgtaaggc catcatgcaa
    20701 tattgtcagc taaagggctt tcctgatgtt gacattgatg atatttattt gggaaatggt
    20761 gtctcagagc tgatttcgat gtctcttcag gccttactgg ataatggtga tgaggtgctg
    20821 gtgccaatgc ctgattaccc cctttggaca gcctgtgtca gcctaggtgg tgggcatgcg
    20881 gtgcattacc tatgtgatga agaggctgag tggtatcctg atattgctga cataaaagcc
    20941 aagatcactg agcgtacaaa ggctatcgtc attatcaatc ctaataaccc aacaggtgct
    21001 ctctacccta gagaggtctt agaggagatt gttgcgattg ccagagagca tcagctcatc
    21061 atttttgcag atgagattta tgatcgtttg gtcatggacg gtggtgagca tatcgcaatt
    21121 gccagccttg cgcctgatgt tttttgtgtg tcaatgaatg ggctgtcaaa atcacaccgt
    21181 attgccggct ttcgagtggg ctggatggtc ttgtcaggtc ctaaaagaca tgtcagaggc
    21241 tacattgaag gcttgaacat gctggcgaat atgcgcttgt gctccaatgt cttggcgcag
    21301 caggtagtgc aaacctcctt aggaggacgt cagtctgttg atgagctttt actgcctggc
    21361 ggtcgtatct ttgagcaacg taacttcatt taccaggcca ttaatgccat tcctggtcta
    21421 tcagctgtaa agcctaaggc aggcctctat ttgtttccga aaattgatcg aaatatgtac
    21481 cgcattgatg acgacgagga atttgtccta cagcttttga agcaagaaaa ggtcatgctg
    21541 gtgcatgggc gtggcttcaa ctggaaggag cctgatcatt ttcgcgtggt ctatctgcca
    21601 acagtagaag agctagctga cgtgcaagaa aagatcacgc gtgttctcaa gcaatacaag
    21661 cgctaatatg attctcatac aaaaattgga tcgcgagatc ctttttgttt ttcagcaaaa
    21721 taaggctctg gcctcatccg aattgtaggt ataatagcca attttctgat aattccttgc
    21781 aaaagctagg gtcctttgat ataattgtaa cgcaaataat taaaaggaaa agaaaaaatg
    21841 ccaaatttat tagaaaaaac ccgtaagatt acttctattt tgcaacgttc tgtagacagc
    21901 ttggaaacag agctaccata taatacgatg gcttcacgct tagcagatat tattgattgt
    21961 aatgcttgta tcatcaatgg tggtggcagc ttacttggct atgcgatgaa gtacaagacc
    22021 aacacagacc gcgtcgagga attttttgaa acaagacagt tcccagatgc ttatgtcaag
    22081 gcagctagtc gtgtttatga cactgaagca aacctttctg tggaaaatga actaacgatt
    22141 tttcctgttg agtcaaagga tatctatcct gatggtttaa ccacgattgc ccctatctat
    22201 ggtggcggca tgcgcttagg taccttgatc atctggcgta acgacaatga attcagtgat
    22261 gatgaccttg ttttagttga aatctcaagc actgtggtcg gtatccagct gttaaatctc
    22321 cagaccgaaa acctagaaga aaccattcgt aagcagacag ctgttaatat ggcaatcaac
    22381 actctatctt actctgaaat gaaggctgtt gcagctatcc ttagtgagct agatggcaat
    22441 gaaggacgcc tgaccgcttc agtgattgca gatcgtattg gaatcacacg atctgtcatc
    22501 gtgaatgccc ttagaaagct agagagtgca ggtatcattg agagtcgctc tctgggaatg
    22561 aagggtacct atctcaaggt gatcaacgaa ggtatctttg acaagctaaa ggaattttaa
    22621 tagctcagat gtcggcaatc gtctgctaag cccaaggctt gcctctagct ctgctagctg
    22681 tgatgagtca gagcaagtag agaaagctct gacactatgt ttagctatga tcaaagcctt
    22741 gctgtctata gcgcaaatca gtcagggctc tgcttggtaa ggactagact tgatctttta
    22801 gggcagctta tcggtgtttc ttagcagctg tggaggactt cacacattat tatagcaacc
    22861 cctcaaaggt tctagcgtta gctagttttt gagggggatt ttttgtattt ttgctgtgat
    22921 tcagcatgag atgaacatga cagatgcatg aaagatgttt agcaagaaaa taaggctttc
    22981 tgtatttcaa tgttcagctg cttcaagaac atgtcttatt ttcatacaga aaaaacgttg
    23041 aaagtgtcta ccttaaatct atactatagt tcagaaataa ctgttttgcg cctttatcgt
    23101 gtataaacca atctactgtc ttgacagctg tcgcatttag tggtaaacta taagtgtcta
    23161 atcatactga atattaaaag caagctttgt tctcatggct tgctgtcatg cagctaagag
    23221 agcataagct ttttggggag ggataagctg tgaaggcctt gatttctatt gattatacga
    23281 atgactttgt agctgatgat ggtagcctga cggcaggagc acctgctcag gtgatttcag
    23341 aggcgatggc tagtactgct gaggctgcct ttgaggctgg ttactatatc ttttttgcga
    23401 ttgatgccca cgaggaggga gatagctttc acccggaggc agccttgttt ccaccgcata
    23461 atattatcgg gacaagaggt cgggacctgt atggtccttt gatgactgta tataccagat
    23521 accagcaaga tcagcgggtc ttttggctgg ataagcggca ttattctgcc ttttcgggga
    23581 ctgatttgga tattcgtctt cgtgagcgtg gcgtcacgac gctggtcttg acaggtgtgc
    23641 tgacggatat ttgtgtcctt catacagcaa ttgatgccta taaattgggc tacaagcttg
    23701 agattatcac atcagcagtg gcgagcaatt caagagaaaa tcaccagtgg gcgcttaacc
    23761 actgtaggac tgtcctggga gccaagctcc ttgatcagct ttcttaggta gtcgtttgat
    23821 tagctggggc agctgatcaa gtaaggtagt accagctgcg atttggctca gcactgatct
    23881 taagggcttg ctagtcagat cctttggtct tggctaggag gctttttgtt atttagcttt
    23941 tcgttacatt ccagccacac atacacatgc attttttgcc ctttttacct catcaattgc
    24001 tcaaatgcag tttagttata gcatagctat tcttgaaaaa aacgacattg atcatgaaaa
    24061 acgttaattt cttcatgcct ttggtgtgaa atcccagtag tctactatgg taaatagagc
    24121 taattatgat ataatgatta agactatgta aaattgggtt attcaggctg ttatcaagcg
    24181 tttgaaacag caaggcttta tggctgatga tggtctgctt taccttggat aggagaattc
    24241 atgaaaattt ctgaagaaga ggtccgccac gttgcggccc tatcaaagct atccttttca
    24301 gaaagtgaaa caaccgagtt tgcgacaaca ttatcaaaaa tcgttgacat ggttgaattg
    24361 ctgaatgaag tggatacgac aggtattgcc attaccacca caatggcaga caagaaaaat
    24421 atcatgcgag ctgatatcgc tgaggctgga gtggatcgca agctcctgtt tcaaaatgtt
    24481 cctgaaaaag aaaatcattt catcaaggta ccagctattc ttgatgatgg aggagatgcc
    24541 taatgtcttt taatcatcac actatagaag aattacatga gcttcttgtt gcaaaggaca
    24601 tttctgcagt tgagctaaca aaggcaaccc ttgaggatat caaggcgcgt gaagaggctg
    24661 tgggttcttt cattaccatt gctgaggagg cagccttgaa gcaggctgcg gcacttgatg
    24721 ccaaggggat tgatcctgac aatgtgatgt caggaatacc actagctgtc aaggacaata
    24781 tctcaaccaa gggaatcctg acaactgctg cctctaagat gctttataat tatgagccga
    24841 tttttgatgc gacagcagta gctaatgcct atgataagga tatgattatc atcggtaaga
    24901 ccaacatgga cgagtttgct atgggtggct caacagaaac gtcttatttc aagaaaacca
    24961 aaaacgcttg ggatcatagc agggttcctg gtggttcatc aggtggctct gcaacagcag
    25021 tagcttcagg tcaggttcgc ttatctcttg gctcagacac tggcggctct attcgtcagc
    25081 cagcagcctt taatggtgtt gttgggctta agccaaccta cggggctgtt tctcgctatg
    25141 gcttgattgc ctttggtagc tcgctagatc agatagggcc ttttgcgcca acggtaagag
    25201 aaaatgctca gctgctatcg gtcattgcag ggagtgaccg caaggactca acctcagcac
    25261 ctgtacagat cgctgactac acaagtaaga tcggtcaaga catcaagggc atgaagattg
    25321 cactacctaa ggaatacctt ggcgaaggca ttgatcctaa gattaaagag acggttttag
    25381 ctgctgctaa gcattttgag aagctgggag ctatcattga ggaggtcagt ctgccacata
    25441 gcaagtatgg ggtggctgtc tattatatca ttgcttcatc tgaggcctca tcaaacctac
    25501 agcgatttga tggtattcgc tatggctttc gtgctgctga tgccaagagc cttgaggaca
    25561 tctatgtcaa gacgcgtagt cagggctttg gtgatgaggt caagcgtcgt atcatgctgg
    25621 gtacctttag cttatcatca ggctattatg acgcttattt caaaaaggcc ggtcaggttc
    25681 ggacgctgat cattcaagat tttgaaaagg tttttgctga ttatgacttg attttaggac
    25741 caacagcacc aacagcagcc tttaagcttg atacgttgaa tcatgatcct gttgccatgt
    25801 atttggctga tcttttgacc attccggtga atctagcggg cttgcctgcg atctctattc
    25861 cagcaggctt tgcagatggc ttacctgttg ggcttcaatt gatcggtcca aaatatagtg
    25921 aagaggtcat ctatcaggca gcagcagcct ttgaagcgac tactgactac cacaagcagc
    25981 agcctatgat ttttggaggt gacagctaat gaattttgaa accattattg gacttgaggt
    26041 ccatgtggag ttgaatacca attctaagat tttctcgcct tcatcagctc attttggaga
    26101 ggatcccaac gccagcacta atgtgattga ctggtctttc ccaggtgtcc tcccagtgat
    26161 gaacaaggga gttattgatg cgggaatcaa agcagcactt gctcttaaca tgtctattca
    26221 tcagcacatg cattttgacc gtaagaatta tttctaccca gataatccca aggcctacca
    26281 gatttcacag tttgatgagc cgattggcta caatggctgg attgatatta ctcttgagga
    26341 cggctcaacc aagaaaatcc gtattgagcg tgctcaccta gaggaggatg ccggcaaaaa
    26401 tacgcatggt acagatggct attcctatgt tgacctcaat cgtcaggggg tgcccttgat
    26461 tgagatcgtc tcagaggctg acatgcgctc tccagaggag gcttatgctt acctgactgc
    26521 cctaaaggaa atcattcagt atactggtat ttctgatgtt aagatggaag aggggtccat
    26581 gcgtgtggac gccaatatct ccttgcgacc atacggacaa gaggcctttg gtacaaaaac
    26641 agaattgaaa aacctgaact catttagcaa tgtgcgtaag gggcttgagt ttgaggtgga
    26701 gcgtcaagcc aaaatcctac gctctggcgg tgttattcgt caggagacac gtcgttatga
    26761 cgaggcaagt aagggaacga ttctcatgcg tgtcaaggag ggaacagcag actaccgcta
    26821 tttcccagag ccagatttgc cattgtttga gattgatgac gcatggattg aggatatgcg
    26881 tgcagagctc ccaaggttcc ccgcagagcg tcgggtaagc tatatcaagg atcttggttt
    26941 gtccgcctac gatgcaggtc agctgacagc aacaaaggct ttatctgatt tctttgagca
    27001 ggctgtggca cttggtggtg acgcaaagca agtgtccaat tggctacagg gtgaggtggc
    27061 tcagttctta aatgctgagg gcaagacgat tgatcagctt gccttgacac cagatagcct
    27121 tgtggaaatg attgcgatca tcgctgatgg cacgatttca tcaaaaatag ctaagaaggt
    27181 ctttgttcat ttggcaaagc atggcggctc agcgcgtgct tatgtggaaa aagcaggtct
    27241 ggttcaaatt tcagacccag ctgtcttgat tccaatcatt catcaggtgt ttgctgacaa
    27301 tgaggctgct gtggcagatt tcaaatcagg caagcgtaat gctgataagg cctttactgg
    27361 ttttctgatg aaggccacaa aggggcaagc caacccacag atagctcagc aattgttagc
    27421 ccaagaattg caaaaattgc tggattaagg agtcgttatg actggcattg agtctgaaac
    27481 agagttttca ggctctttat gatggtaggc tctttaggac aattctgtga taatacctcg
    27541 ctatccgaag ctgtaagagg tagcttatcg gtctgttgtt aatgactgtt aagcaggctt
    27601 ggtgaagtct aggctagagc tatcaaggta ttatgagtgg ccttatcatg gcatggatta
    27661 aaaagaggaa gataatatgt caagaaatgg aaaaggcagt accatgattt tactagccgg
    27721 aatcgcctgg ggtctctcag gggtgtcagg gcaatattta attgctcatg gggtcggcat
    27781 caatgccttg acctcactaa ggctcattat ttcagggctt gtgctatcaa gtatggccta
    27841 tatgcgacag cgagacgctg ttatccgact gctcaaggac aaaaggcttt taagagagct
    27901 attgatttat agcctatttg gcctcacgct gaatcaatat gcctatttgc tggctattcg
    27961 ttattctaac gctggtacag ctacagtcct gcaatacctt tcccccattt tggtgctggt
    28021 ctatctatcg ttcaagtcaa gacgcctgcc ggctgcggga gagagctgtg ctatttgcct
    28081 agcgatccta ggaacggtta tcatggcctg tcatggggac ttgtcgcatc tagcgattaa
    28141 tcctatcggg cttttctggg ggctttttgc agcggtgacc tatgcttact gtgtcatcaa
    28201 gcctgctaag ctgattgccg cctgggggag cttgctgatt gttggtcttg ccatgctgat
    28261 gggaggagtg atttttccga tcctgacaag agcatggcag tacccattgg caatgactta
    28321 tgggaatcta cgggccctgt ttggcattat cggtattggg acaatttttg cctacacctt
    28381 ttttctaaag ggggcttcaa tcattgggcc gatcaaggct accttgctgg cttcaattga
    28441 gccggttgct tcagtctttt ttgcgattat cctgatgaaa gagacttttc accctattga
    28501 cctgttaggg atggcattga ttttaatagc agtgcttgtg atatcgctga gagacttact
    28561 gcttgctcaa agaaaaaagc agctagctct taaggccaag cgactaccat catctgactg
    28621 atatagagca agggtgtgct ataataagac aaaacataaa ggagatttgt gatgatttgg
    28681 tcattaattg ttggtgccat cattggtatg attgcaggca ggataacaga aaaaagccat
    28741 tcgatgggct gtttcacaat gactgctgct ggtttgatag gctctgcagt tggtcaaaag
    28801 ctgtttggcg actggggtat tcagctggca ggcatggctg ttttcccttc aattctagga
    28861 gcagctattg tgataattgt tgcttcagcg ctctttggca aaaaacaata agccaggagt
    28921 acttgtgacg ttcagatata taaaaatcct tgtatcggta tgatacgagg attttttggt
//
LOCUS       DARYSY010000025        28709 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYSY010000025 DARYSY010000000
VERSION     DARYSY010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28709
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            37..1371
                     /gene="pepC"
                     /locus_tag="TVR04_001007"
     CDS             37..1371
                     /gene="pepC"
                     /locus_tag="TVR04_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1269708.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAQ"
     gene            complement(1440..1622)
                     /locus_tag="TVR04_001008"
                     /pseudo
     CDS             complement(1440..1622)
                     /locus_tag="TVR04_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1760..3925)
                     /locus_tag="TVR04_001009"
     CDS             complement(1760..3925)
                     /locus_tag="TVR04_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1269709.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKRLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSEDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     SSSQSSDEDTTEDSHTEANDSTTSSSEQHSSSTDDKKTN"
     gene            complement(3912..4520)
                     /gene="recU"
                     /locus_tag="TVR04_001010"
     CDS             complement(3912..4520)
                     /gene="recU"
                     /locus_tag="TVR04_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1269710.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHRQVDFANRGMSFEAAINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            4596..5111
                     /locus_tag="TVR04_001011"
     CDS             4596..5111
                     /locus_tag="TVR04_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1269711.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIKRDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQHLQQFRATDF
                     VKYSYPSYESPKHLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            5233..5556
                     /gene="gpsB"
                     /locus_tag="TVR04_001012"
     CDS             5233..5556
                     /gene="gpsB"
                     /locus_tag="TVR04_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1269712.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            5570..5938
                     /gene="rnpB"
                     /locus_tag="TVR04_001013"
     ncRNA           5570..5938
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TVR04_001013"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            6002..7156
                     /locus_tag="TVR04_001014"
     CDS             6002..7156
                     /locus_tag="TVR04_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1269713.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVK
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRLEKGGAPIKENMAAAILELSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKKNA
                     EEAGLADVITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMGQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            7170..8621
                     /locus_tag="TVR04_001015"
     CDS             7170..8621
                     /locus_tag="TVR04_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269714.1"
                     /translation="MSEKSKAVESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPADETSLIEPAAAKAGTPALATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTS
                     KTKADAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFITAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFRPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(8768..9253)
                     /locus_tag="TVR04_001016"
     CDS             complement(8768..9253)
                     /locus_tag="TVR04_001016"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1269715.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     ITSSLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            9410..11020
                     /locus_tag="TVR04_001017"
     CDS             9410..11020
                     /locus_tag="TVR04_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1269716.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAEADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQRSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIREMRAIDYAK"
     gene            11184..11810
                     /gene="gmk"
                     /locus_tag="TVR04_001018"
     CDS             11184..11810
                     /gene="gmk"
                     /locus_tag="TVR04_001018"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1269717.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGVDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            11835..12152
                     /locus_tag="TVR04_001019"
     CDS             11835..12152
                     /locus_tag="TVR04_001019"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1269718.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQAFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            12216..14600
                     /locus_tag="TVR04_001020"
     CDS             12216..14600
                     /locus_tag="TVR04_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1269719.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSNQSTQQLKPIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTAALAAADLAAFFSDGDSLLYSKLSPEQEGRVLRLIQSGKIK
                     ATYLAKDKKTIKIEKYYQVNKSALQEHKISNRAKKRQALKAYLLANPQKNKLAKLYQD
                     YSREVVSYFVANQLIELEEQRVNRSEAYFNHIKAAPLLKLNQQQQQAVDQITKAVGKE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQITSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALLRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTFHMDTKTMNCHYCGFQRAIPRLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILKAFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGLRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQMMTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            14667..15602
                     /locus_tag="TVR04_001021"
     CDS             14667..15602
                     /locus_tag="TVR04_001021"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1269720.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLENPAYNILAVVTQPDRAVGRKKE
                     ITMTPVKELALAHQLPIFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            15592..16914
                     /gene="rsmB"
                     /locus_tag="TVR04_001022"
     CDS             15592..16914
                     /gene="rsmB"
                     /locus_tag="TVR04_001022"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1269721.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARARGRGADKLVNAVLRQLTTNPLPDMTSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAVMESLFVRSRASIRVTDLAKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            16952..17692
                     /locus_tag="TVR04_001023"
     CDS             16952..17692
                     /locus_tag="TVR04_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1269722.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVREGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            17689..19584
                     /gene="pknB"
                     /locus_tag="TVR04_001024"
     CDS             17689..19584
                     /gene="pknB"
                     /locus_tag="TVR04_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1269723.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            19717..20409
                     /locus_tag="TVR04_001025"
     CDS             19717..20409
                     /locus_tag="TVR04_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1269724.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGETEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            20406..21410
                     /locus_tag="TVR04_001026"
     CDS             20406..21410
                     /locus_tag="TVR04_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1269725.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLKQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMDQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            21403..22044
                     /locus_tag="TVR04_001027"
     CDS             21403..22044
                     /locus_tag="TVR04_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269726.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALALRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            22078..23478
                     /locus_tag="TVR04_001028"
     CDS             22078..23478
                     /locus_tag="TVR04_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1269727.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLEADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     EWANTVGIDYGMAGRHKAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPAELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLASYEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEALYNLRGALSMANAGPNTNGSQFFIVQNASLP
                     YSQKELERGGWPKDIAAAYAEHGGTPHLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIETIEVFD"
     gene            23478..23840
                     /locus_tag="TVR04_001029"
     CDS             23478..23840
                     /locus_tag="TVR04_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1269728.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(24256..25182)
                     /gene="cysK"
                     /locus_tag="TVR04_001030"
     CDS             complement(24256..25182)
                     /gene="cysK"
                     /locus_tag="TVR04_001030"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1269729.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVIIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIEVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEEPSS
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(25303..25944)
                     /locus_tag="TVR04_001031"
     CDS             complement(25303..25944)
                     /locus_tag="TVR04_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1269730.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GIKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLDQEGLIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAD"
     gene            26000..27322
                     /locus_tag="TVR04_001032"
     CDS             26000..27322
                     /locus_tag="TVR04_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1269731.1"
                     /translation="MENIENYYGRLLPERQCPKAVSVWACSLQSMIAKKGTLYCQRCS
                     SLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPPAPFPKAHYLRWQGQLTTYQGAV
                     SHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVDKGGWVCIASPRVDVCIELEKR
                     LSRDFSCQVCLMHAESEAYHRSPIIIATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQL
                     NHAAHQAAKADAVTVYLTATSTKDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFS
                     LLEAINRGKLPRRFITLVKKQRATGYPLLIFFPLIELAEQCCQLLQKYFPKETIAHAS
                     SQSSNRMTIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISG
                     RVGRSLERPEGQVLFFHDGISQAMLKAVREIKDMNQKGYQNELSTLPQ"
     gene            27297..27962
                     /locus_tag="TVR04_001033"
     CDS             27297..27962
                     /locus_tag="TVR04_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1269732.1"
                     /translation="MNCLLCHNNSKDSLSITAILLLSPNKDLMCDACQRHFCRITQPT
                     CSNCYQYRYEGACQDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFA
                     HELAKHIKKYYKAYTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERTDDTRQS
                     SKTKKERLQLNNRYRLKKGAVLPRKILLIDDIYTTGSTIMSLRQELIRHGCQDIKSLS
                     IAR"
     gene            28038..28586
                     /gene="raiA"
                     /locus_tag="TVR04_001034"
     CDS             28038..28586
                     /gene="raiA"
                     /locus_tag="TVR04_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1269733.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEQAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
BASE COUNT         8403 a         5584 c         6652 g         8070 t
ORIGIN      
        1 ttaggtgttg ttatttatta tctttggagg aaaatgatgt cagtattaac agagacattt
       61 acagaacagc tatatgctaa ttatgaagct aatgctaaat atttagctct tgaaaatgcc
      121 attactcaca atggcttgct taaatccttg gagacaagac aaagtgagat cgacaatgat
      181 tttgtctttt ccattgactt gacaaaggat aaagtctcta atcaaaaggc ttcaggtcgt
      241 tgctggatgt ttgcagcctt aaacaccttt cgccataagc ttatttcaga atttaaatta
      301 gaagattttg agttgtcaca agcacacacc tttttctggg acaaatacga aaaatcaaac
      361 tggtttatgg aacaggtgat tgcaactgct gatcaagcct tgactagccg tagggttaag
      421 tttcttttgg acgttccgca gcaagacggt ggtcagtggg acatggttgt agccctgttt
      481 gaaaaatacg gtgttgtgcc aaaatcagtc tacccagagt ctgtgtcatc aagcaatagt
      541 cgtgagttaa atcaatacct caataagctc ttgcgtcagg acgctcagat tcttcgagat
      601 gtgatcagtg ctggtgctga tcatcaggca gtacaggcta aaaaagaaga gctacttcag
      661 gaaatcttta atttcttagc catgaatctt ggtttgccac ctcgtcaatt tgattttgct
      721 tatcgtgata aggataatca ctatcatgct gataagggca tcacaccaca ggcattttat
      781 gaaaaatatg ttggtctaaa gctgtctgat tatgtgtctg ttatcaacgc cccaacagct
      841 gataagcctt atggcaaatc ttatacggtt gatatgcttg gtaatgttgt tggcagtcct
      901 gaggtgcgct accttaatct tgatatggag cgcttcaagg agcttgctat taagcaaatg
      961 caggctggag agtccgtttg gtttggttca gatgttggtc aagtatcaga ccgtcaaaag
     1021 ggtatcttag cccttaatac ctatgatttt caggcaggca tggatattca attgagtcaa
     1081 gacaaggctg gtcgacttga ttacagcgaa agcttaatga cacatgctat ggttttgaca
     1141 ggtgttgatt tagatgatac tggcaagcct atcaaatgga aggttgaaaa ttcttgggga
     1201 gataaggttg gtgacaaagg ctactttgtt gcttctgatg cttggatgga cgagtatact
     1261 tatcagattg tggttcgcaa ggatctccta acagctgatg agctagcagc ctatgaggca
     1321 gagccacagg tgcttgctcc ttgggatccg atgggtgcct tagcccaata atcataacca
     1381 tccgtcaata aaccgcaccc caatcgttag attttctgtc taacttttga ggtgcggttc
     1441 atttcgatga aggggatttt agaaggcttt tggaagtcgt atttgatttg tttgcctttg
     1501 cagtgtctac acttaggagg gttatagtca agagtggcta aaagctcaat ataagtttcg
     1561 ttcatcaaaa ctttgtttag agtgatattt ttgtctctga ttctaatgag ttgtttgatc
     1621 acttttcatg ataagttatg ggactttttg atacactcaa aaagccctat aatctccgag
     1681 gtggagttac ccactacaga aatgatagag ccaataatta aaaaccctgg ttcagaacac
     1741 ttgagccagg gttttgttgt cagttggttt tcttatcatc ggtggagctt gaatgctgct
     1801 ctgatgatga cgttgtgctg tcgtttgctt ctgtgtggct gtcttcagtt gtatcctcgt
     1861 ctgaggattg gcttgaagat gagctgttat taccgtagag gttgttgtag acagagcttg
     1921 tataatcact gctgtttgta taggtaccac ttaggtagag gaagccgccg ctgcgataga
     1981 gcccgcttgg catggtccaa tcctcgctgt agccaccagt gagatagctg atcatattgc
     2041 gataaacatg agaagcaatt tctaggctgt agccataaat tggcgtcata cggtttttat
     2101 aaccggtcca aactgccata gcgtatcggt tggtgtagcc aacaaagttt tcatctggag
     2161 ccattgttcc cacataatca ggggatagtc catgtgtctc aacaatttgt gccagctcct
     2221 catcggtata gtttgaggta ccagttttac cagcctgtgc aactcctggg atagccgcag
     2281 cagtacctgt accgtaggtt agtaccgttt ttagcatatc agtcatcata taggctgttg
     2341 tttccttcat ggcacgcttg cccttgtttt cgataacctt gctggtgccg tcgctgaatt
     2401 caattttgtt gacgtattgt ggcttataat agagtccacc gttggcaaaa gccgcatagg
     2461 cagcagccat tttttcactg cttgcaccgt attttgaatc agagctgcta ttgttacttg
     2521 agatggcatt tgaataatgc atctctggat agttaatgcc cagatcactg aggaaggatt
     2581 gtgcatagct aagtcctgcc gcctctagag ccctaactgc agggacgttt cgtgattgca
     2641 tgagagcagc ttgaatggtc atccagccat agtatctacg gtcccagtta tagagctgag
     2701 tgtgtgtccc tggccaatag tagacagagt cgttagttgt ttgagctgta gagttgtaag
     2761 caccagattc aatagcaggt ccatagtctg tgatcggctt catggtggat ccccagtcac
     2821 gatcggttaa gacagcctga ttggttccaa aggaaacgtt ggtatcctga ttgcgtcctc
     2881 ctaattgggc gataacgtgt ccattagtga catcaataac ggttgaggcc acctgaaagt
     2941 cagcatcagg gtaatacaca tagtcctcag aattgtagat gtcataaagt cttttttggg
     3001 cctctggaat gatgtttgtg taaaccttta gaccagaggt aaaaatatcc ttgttggtct
     3061 cagcctttac ctgctcgatc acttgcttta agtaattatc catgtatttt ggatagctgg
     3121 cgcgttgctg gagaggctgt aggccttctg atataggtgt ggcgatagct gcctcgtact
     3181 cagccttggt aatgttcttt tcagcataca tttgctgaag gacaatattt cggcggcttt
     3241 gagctgtctc aggctgtgtg taggggtcat attggcttgg cgcctgtgga atccctgcca
     3301 gcaaggctag ctgagcatag gacaagtctt tcaaatcctt gccataatag gccttggctg
     3361 ctgtcagcat accataatta ccatttccca tataaacctt gttgatgtag aaggtcagga
     3421 tttcttgctt ggtatatttt cgctccattt gaagggccag ccaaacctcc tgagcttttc
     3481 gcttcaaggt ctggtcagac tcgtttgtcg agaagtaggc tagcttaatc agctgctgat
     3541 caagtgtaga ccccccttgg gttgttttgc ttgttaaatt gtgaaaggct gcacctaaga
     3601 tacgatagag atcaacacct cgatgattaa aaaagcgctt gtcttctata gaaatgatag
     3661 cattgaccag attgatagga atgctgtctg ctgtaacatt ttcacgcttt tcagagccca
     3721 agtcagcaat caaatgatta ttaccgtcat aaacaaggct ggaattggtc gatttgagct
     3781 gggcctcaga aagcttaggg gcactgctga tatagtaagc aaacaaaagg ccacctaagg
     3841 taattgtcac aatgataagg ctaaggatag cacctaatgt atacttcagg aatttaagga
     3901 tttttggatt gttaattgta atcaccgcct aaaaattttt gttctataat atctaaataa
     3961 ggaacctgtg gaaatgctcc cagcttgacc tcaaagccgt tttttctgat ataatcaagt
     4021 ggcattgatt tgttgcccct atcaatctga taaaaatcaa tgagtgcttt ggcaggtaga
     4081 taataggttt cctttagtgt cgcaaagtga aggaggacaa agcaaatgcc tttttgcttt
     4141 aaaacagcag ccatgtgctc aatctgatgc gcgtgaaaat ttttcattgg catagctgtt
     4201 ttttgccttg tttccttagc ttcaaaatca atataatgcc ctttgtagat accggagtag
     4261 tctgttgttg aagcctgctt aaaataagcc tcaacaatct tggctcgact acgtcttgga
     4321 tagtctacct tgacaatctg tatcggagtt ggctttttat gaatgacagc aatccctttg
     4381 gccaagtaat aagcgttggt tgcattaatg gctgcttcaa aggacatacc acgattggca
     4441 aaatctactt gcctgtgctt ttgctgcttt tgaagagggg tcaccttctg gcgaatagga
     4501 ttatgagggt agttaaccat tgttctccta acatcatgac ttaataataa tttaagcatt
     4561 cacattataa catatttttg aaaggataac atctaatgac tgcaattctc gtgacaggct
     4621 atcgaagttt tgagctgggc atctttagtg aaaaggataa aagagttgcc attatcaaaa
     4681 aagcgatcaa aagagatctg attgcttatc ttgaggaggg cgtagactgg tttattttta
     4741 ctgggaattt agggtttgag cagtgggctt tagaggtagc taatgacctc aaaaagacct
     4801 accccttaaa gacagcgact atttttgcct ttgaaacgca tggcagcact tggaatgatc
     4861 gcaatcagca gcacctgcag caatttcggg cgactgattt tgtcaaatat agctatccca
     4921 gctatgaaag ccctaaacac ctaaagagct accatcactt tttgattcac aatacagacg
     4981 gagcctatct tttttatgat agtgagcacg aaacgcgcct aagctatttg gtagcagcta
     5041 tgaaggagca gccctgttac cccctttctt tcctaaactt tgagcgttta aatgacattg
     5101 cagatgagta gctagtgata tttaaaaatc actggtattt aaatacttgc tttttaattt
     5161 atttttctgt atcataagta atgatatcaa agtttgatat ttgaaaaaga ttgaccgttt
     5221 ggagagtata gaatgacagg tataatttat agtccaaagg acatttttga gcaagaattt
     5281 aagaccagta tgcgtggctt tgataagaag gaggtcgacg aattccttga taacgtcatc
     5341 aaggattatg agtatttcaa tgctcagatc gaggccctaa aggctgaaaa tgaagcctta
     5401 aaaaaggcta aggctcaggt gcgtgatcct ttagcaggca gctctcaggc ggtatcacag
     5461 ccaaccagag tagcacagtc agccaccaat tttgacatgc taaagcgcat tagcaagctg
     5521 gaaaaagagg tttttggaaa gcaaattatt gagtaatagt agatgtgcaa tttttggata
     5581 atcgcgtagt attgcaatac tatgaggaaa gtccatgcta gcaccggctg tgatgctggt
     5641 agtgtttgtg ctaggcgaac aaataagcct agggatgtgt ttgacacatt acggcgagtg
     5701 aaatggctaa gtccttgata tgccagagta gctctgaaag tgccacagtg acggagtttt
     5761 tatggaaacg taaaaagtgg aacgcggtaa acccctcaag ctagcaaccc aaactttggt
     5821 aggggcatgg gatagttgga aacgaacaag ctatcctgac tgttgataaa cagtagacag
     5881 atgattatcg aaggagataa tacctagtta tttctggaac aaaacatggc ttatagaaaa
     5941 ttgcataata ggttaagcta gcatatgcta gcttttattt ggttaggata gaaagagtca
     6001 tatgaaagaa caatttacat tagtagcaac tgcagcagct ggcctagagg ctgttgtggg
     6061 taaggaatta agggccttgg gatttgactg ccgagtagat aatggcaagg tcttctttga
     6121 aggcgatatt gaagctattg ctaaggcaaa tctctggctg cgagcggctg accgtatcaa
     6181 gattattgta ggtcagttcc cggcacgaag ctttgaggag ctgtttcagg gggtatttgc
     6241 cttagattgg gagcattatt tgcccttagg tgccaggttt cctattgcaa aggctaagtg
     6301 tgttaagtca accctgcaca acgagccaag tgttcaggct attaccaaaa aagccattgt
     6361 cagaaaattg cagcagcatt ttcatagacc agaacatatt cctttgcaag aggtgggggc
     6421 tgagttcaaa attgaggtct caatcctaaa ggatcaggct accctgatga ttgatactag
     6481 tggctcaagt ctatttaagc gtggctaccg attggaaaaa ggcggagctc ctattaagga
     6541 aaacatggca gcagcaattc ttgagctgtc taattggttt cctgataagc ctttggttga
     6601 tccaacctgt ggatccggga ccttttgtat cgaggcagct cttattggaa tgaatatcgc
     6661 tcctggcttt aatcgctcct ttgcttttga ggaatggagc tgggtagata aagatcgtgt
     6721 tcaaaaggtt cgtgacgctg ctgaaaaaga ggctaattat gatattgagc tggatatttc
     6781 aggctttgat attgacggtc gtatggttga gcttgccaag aaaaatgctg aggaggctgg
     6841 cttggctgat gtcattacct ttaagcaaat gcgcttgcag gatttccgta cagacaagat
     6901 aaacggtgtc atcatttcaa atcctcctta tggagagcgt ttgcttgatg acaaagcagt
     6961 agacatcttg tataatgaga tgggacaggt ctttgctccg ttagttacct ggagcaagtt
     7021 tattttgacg agtgatgatc actttgagca aaaatatggc caaaaagctg ataaaaaacg
     7081 taagctttat aatggtactc taagggttga tttgtatcaa ttttatggag agagggtaaa
     7141 gcgcaatctg atctagagag gtaaaaaacg tgtcagaaaa aagcaaagca gttgaatcag
     7201 aagcagaaag ccaaaatctg gagcttcatg aagccaaaaa aatgacaatc ggtgaggcag
     7261 tgcgcaagga ctcagagcta aaagcaggga ttaccgagga cgatagtgtt ttagacaaat
     7321 acattaagcg acatcgtaac gaagtgtcat cgcaaaagtt tgatgcaaag tatatggagt
     7381 tagatacagc aagtttggat aactttatca aaaaacaaag agaggagctc agtaaagctg
     7441 gtttagttga tgtcgagcca gtggacgagg cttcaacaga ggagaagcca gctgatgaga
     7501 cctccttgat tgagcctgca gcagctaaag ctggtactcc agcgttagct actgattctg
     7561 ctagtgactt tactgggcag ctagctgatg acgcagttag tgagcgacct gcagaagtag
     7621 agagtatttt atcagatagc tatgctagtc gtaggtctaa aaagaaaaag cctctgtttg
     7681 ctattttgtt agccacgcta acccttgtag cctcagcctt tgccctcaac catatctatc
     7741 agttgtctaa gcataagcct cagtcaaagg ctactgtttc taaaaaagca aggagcaaag
     7801 catcaacagc taatcagacc agcaaaacaa aggctgatgc taaggctttt gaagatcttt
     7861 acaagacatt tttcacagat aatgataaaa caaccctaaa aaatagcgcc tttgatcagt
     7921 taccgaattt ggagactgct ttaaaaaggc ttgaggggac agcctattat gacaaggcta
     7981 aggaaaaggt tactgggctg aaaaagcaag taacagctat tcaggcggtt aatgggaaat
     8041 ttataacagc tgcaattgtc aatggtgaaa agattgcagc tgaggtcaaa gctgatgcta
     8101 attttgatga cctagctagt gatacgctaa ccactggtaa tgcaaaactt gattcattgc
     8161 tacaatcaag catcaaggca ggtcgtgagc agctagcaag caggtctgct acccaagcag
     8221 ctagcactcc agctgcttct gccttaccag caagccctgc agctccgcag gttcctgctg
     8281 taccagctcc agtggctcca atgtatggca ttacaggcta tgacccttca atattgcagc
     8341 gtgacctgtc tcgtgtgccc tacaatcagg ctatgattgc tgatacagga aaccctgctt
     8401 gggcctttaa tccaggtgtg cttgagcgta ttgtggctac ctcacaagca aggggctata
     8461 tttcaggcaa tgattatatc ctggagccgg tcaatattat caatgggaat ggctattaca
     8521 acatgtttag gcctgatggc acctacctct tttcattgaa ttgcaaaaca ggctattttg
     8581 tcggaaatgg caaagggcat gcagaggact tagactatta atctttagaa gacaaggtgt
     8641 gatcctgagc tggataccct agttatcaca ggtgctaaaa ggcaaaggga ttgagccctg
     8701 cctttagcac ctttttgaat gcattaaaag cctccttttc attagcagaa aagcgaggct
     8761 ttcattgtta tgaggtgaca tggcggttaa atggatcatc agagatccct tgcttgagaa
     8821 taagctgggc ccattcctta gcagcaaaaa ggctgtggtc cttgtaattg ccgcaggatt
     8881 caatggttgt tccgggaacg tcctcccaag tgatgcctgt agcgatttcc tctaggctgg
     8941 acgtgataac cttagcaatg tctgttgagc tgtgcttgcc ccacatgatg aggtgaaagc
     9001 ctgtgcggca gccaaagggg gagcaatcaa tcattccatc aatgcgttga cgaatgagct
     9061 tggctaataa atgctcgatg gtgtgtaaac cggcagtctc aatggcagcc tgattaggct
     9121 gaacaagtcg aacatcaaaa tttgtaatca catctccctg gggcccaaat tcctcggaga
     9181 ttagccgtac atagggtgcc ttaacaatag tatgatcaag ctcaaagctt tcaacaataa
     9241 cttcttttgg cataagaaac tcctttttat ttttatcaat atcataacat aaaatcacta
     9301 gattttagaa aaatgtaggt ggattttaaa ttgtctaaat cttcatttta tgatagacta
     9361 agagatggct ttctgttaat gaaaactaaa ctattattga ggtaaagaca tgttaattaa
     9421 tatcataaca ttgcttgtct gtggcctcat tggtgtaata ttaggttatg cacttatttc
     9481 gattagactc aagtctgcga aggaagctgc agagttgact cttttaaacg ctgaacagga
     9541 tgctgttgat attcgtggca aggcagaggc tgatgctgct catatcaaaa agacagcaca
     9601 acgtgaaagt aaagcaagtc gtaaagaatt acttttagaa gcaaaggaag aggcaagaaa
     9661 gtatcgtgaa gaaattgaac aggaatttaa atctgaaaga caagagctta aacagctgga
     9721 gacgcgctta gcagagcgtg ctctaactct tgatcgtaag gatgaaaatc tatcaagtaa
     9781 agaaaaagta ctagatagca aagagcaaag tctgaccgat aaatctaagc acattgatga
     9841 gcgacaggca caggttgaaa aacttgagga agacaaaaga gcagagctcc aacgagttgc
     9901 tgctatgact attgcagagg cgcgtgaggt tatcctgatg gagactgaaa acaagctgac
     9961 gcatgagatc gcaacacgca ttcgtgatgc agagcgtgac atcaaggaca ggacagacaa
    10021 gactgctaag gacctgcttg cacaggccat gcaacgtatg gctggtgagt atgtgactga
    10081 gcagacgatt acaagtgtgc acttgcctga tgataacatg aaagggcgta ttatcggtcg
    10141 agagggtcgc aatatccgta ctctagagag tctgacaggg attgatgtga tcattgacga
    10201 taccccagaa gtggttgttt tatcaggctt tgaccctatt cgtcgagaga ttgctcgtat
    10261 gaccctagag tccttgattg ctgatggtcg tattcacccg gcgcgtatcg aggaattggt
    10321 tgagaaaaat cgtcttgaga tggacaatag gattcgtgaa tatggtgagg ctgctgccta
    10381 tgagatcggt gcgcctaacc tccacccgga tttgattaag atcatggggc gtttacagtt
    10441 tcgtacctca tttggtcaaa atgttttacg ccactcagtc gaggttggta agctagctgg
    10501 tattttagct ggcgagcttg gtgaaaatgt ggcacttgca cgtcgcgcag gtttcttgca
    10561 tgatatgggc aaggctattg atcgtgaggt tgaaggaagc cacgttgaga ttggtatgga
    10621 gtttgctcgc aagtacaagg agcaccctgt tgttgtgaac accatagcca gccatcatgg
    10681 cgatgtcgag ccagattcgg ttattgcggt tctggtagct gctgctgatg cccttagctc
    10741 tgctcgtcca ggtgctcgca atgaatctgt ggaaaactat atcaagcgtc ttcgtgacct
    10801 tgaagaaatc gcaacaagct ttgatggtgt tcaaagaagc tttgccctcc aagccggtcg
    10861 agagattcgc atcatggttc agccagaaaa gatttctgat gacgagattg tggtcctctc
    10921 acataaggtc agagaaaaga ttgaaaataa tctggattac ccaggaaata tcaaggtaac
    10981 cgttattcgt gaaatgcgag caatagatta tgctaaataa aaaaggaaag agtgtatgct
    11041 tttcaaaagc cagagcttag cctctagctt tgagaaggcg tatatctctt cctttttctt
    11101 tcttaggatt gggctgataa ttgtcttgaa aaacgatagc ctttttgata aactattaga
    11161 aagcaatcaa taaggagaac acaatgtctg aacgcggttt gttaatcgtt ttctctggcc
    11221 cctcaggtgt cggaaaggga acggtgagac aagagatttt ttcaacgcca gatcataaat
    11281 ttgaatattc tgtttcgatg acgacacgtc cacagagacc aggtgaagtt gatggggttg
    11341 attatttctt ccgcacacga gaagaatttg aagagctaat aaaaaatggt caaatgctag
    11401 aatatgcaga gtatgtcggc aattactatg gcactccctt aacctatgtt aatgaaaccc
    11461 ttgataaggg tgttgatgtc tttttagaaa ttgaggtaca gggtgctttg caggtaaagg
    11521 ctaaggtgcc tgatggtgtc ttcatttttc taacgccgcc agacttagat gaattgcagg
    11581 accgtttggt tggtcgtgga acagacagcc aagaggtgat tgccaagcgt atcgaaagag
    11641 ctaaggaaga gattgcgctc atgcgagagt atgattatgc tgtggtcaac gacgaggttc
    11701 ctctagctgc tgagcgtgtc aagcgtatta ttgagaccga gcattttcgc gttgagcgtg
    11761 tgattggtcg ctatgaccaa atgattaaaa caacaaaatc tctcagatga tagaaataga
    11821 aaagagtaaa gcccatgatg ttaaaacctt caattgatac tttattagat aaagtcccat
    11881 caaaatattc acttgttatt ttacaggcca agcgtgctca cgaattagaa gcaggtgcta
    11941 caccgacaca ggcctttaag tctgtcaaat caacacttca ggcactagag gagattgagt
    12001 caggcaatgt tgtgattcac ccggatcctg ctgctaagcg tgcggctgtt cgtgcaagga
    12061 ttgaggcaga gcgtttagca agagaagaag aagagcgtaa aataaaagag cagatcgcaa
    12121 aagaaaaaga agaagaggga gaaaaaatct aaggttgagt caatcttagt ttttttcata
    12181 ttgcaggtcc atttcttgat agaaaggaag tcaaaatgca acacatagca caggtcattg
    12241 ttgatattcc cttgatgcaa accgataagc ccttttctta tcttattcca gatgagctat
    12301 tatctctggt taagattggt tctcgcgttc atgtgccctt tggcaatggc aataggctgc
    12361 tgcagggctt tgtcattggc ttttctaatc agtcaacaca gcaattgaag cctatttggt
    12421 cagttttaga tgctgagcct gtcttgaatc aggagcaggt ggcgttagca gagcaattgc
    12481 gacaaacagt cttttcctac aaaatcaccc tcttaaaagc aatgcttcct agcctactca
    12541 attctcatta cgatcgactg ctcaccccga cagctgcctt agctgcggct gaccttgctg
    12601 cttttttctc tgatggggat tccttgcttt attctaagct aagtccagag caggagggac
    12661 gtgtccttag gctgatacag tctggtaaga ttaaggcaac ttatctagcc aaggacaaaa
    12721 aaacaatcaa aattgaaaaa tactatcagg tcaataaatc agctttacag gagcataaga
    12781 tttcaaatcg agctaaaaag cgccaagcct taaaggctta tttgttagct aacccacaga
    12841 aaaataaact ggccaagctt tatcaggatt attctagaga ggttgttagc tattttgtgg
    12901 ctaaccagtt gattgagctt gaggagcagc gtgtcaatcg cagcgaggct tatttcaatc
    12961 acatcaaggc agccccgctc ttaaagctta atcagcagca acaacaagct gttgaccaga
    13021 ttacgaaggc tgttggtaag gaggcaaaac cctttttact ggaaggtatt acaggttctg
    13081 gcaagacaga ggtctatctt catgtgattg cgcatgtgct tgagcaagga aagacagcta
    13141 ttgtcttagt gccagaaatc tccctcacgc ctcaaataac ctctcgattt atttcccgct
    13201 ttggaagaca ggtcgctatt atgcattcag gcttgtcaga tggagaaaaa tttgacgaat
    13261 ggcagaaaat taagacaggg caggctagag tggtggtagg tgctcgctct gctatttttt
    13321 cacctttaga aaatattggt gccattatta ttgatgagga gcatgaggcc acctacaagc
    13381 aggaatctaa tcccagatac catgccagag atgtggccct gcttcgtgca aggcatcata
    13441 aggctgcctt agtgatgggc tcagcgacac ctagtattga cagtcgtgct agagccagca
    13501 agggactgta tcagtttatc cagctgactg agcgagccaa tcctcttgcc agtatgcctc
    13561 aggttgagat tgttgatttt cgagattata ttggtcagca ggaggttagc agcttcaccc
    13621 cttatttgat tgataaactc aaagagcgtc ttgctagaaa agagcaggct gttttgatgc
    13681 tcaacaggcg tggctactct agctttatca tgtgtcgaga ttgtggctat gttgatcaat
    13741 gtccaaattg tgatatttcc ttaaccttcc acatggatac gaaaaccatg aattgtcact
    13801 attgcggctt tcaaagagct attccgaggc tctgtcctag ctgtcaaggc aaaagcatac
    13861 gctattatgg aacagggacg caaaaggcct atgatgagct taagcaggta ttgccagaag
    13921 ccagaatatt acgaatggac gtggatacaa cccgcaaaaa aggcagtcac gaagctattt
    13981 taaaggcgtt tggtaatggt gatgctgatg tgctgcttgg cacacaaatg attgcaaagg
    14041 ggttggattt tcccaatgtt actctagtag gtgttttaaa tgcagatact tccttgcatt
    14101 tacctgattt tagggcatca gagcgaacct ttcaattgct gacccaggtt gcaggacgag
    14161 cagggcgtgc agacaagcca ggtgaagtcc tgattcagac ctacaatcct gagcattacg
    14221 cgattcaact ggctaaaaag caggattttg aagcctttta cgcttatgaa atggggcttc
    14281 gacgaaagct aggctatcct ccctattatt tcacagtagg tctgacccta tcgcataaga
    14341 gtgagcagga ggtggtcaaa aaggcctatc aaatgatgac catattgaag cagggcttgt
    14401 ctgatcagat cagaatatta gggccaacgc caaagccgat tgcaagaacg cacaatcttt
    14461 accattatca gattattttg aaatatcgtt ttgaggatca gcttgaagct accctgaatc
    14521 aaattcttga ttggagccaa gagcaggata atcgcgagct aaaggttatc attgatcaag
    14581 agccacagag ctttatgtaa gtgttcttta ccggactttg cgccaagcta tgctataatg
    14641 aaaaagaaag aaaatagagg acatagatga caagattaat ttttatgggc actccccaat
    14701 tttcagcaac cgttttgcag ggcttactag aaaacccagc ctataacatt ttagcggtcg
    14761 tgacccagcc tgatcgtgcg gtcggtcgca aaaaagaaat cacaatgaca cctgtcaaag
    14821 agctggcgct tgcacatcag ctgcctattt ttcagcctga gaagctatct ggttcacagg
    14881 agctagcaga tatcatggca ttaggagcag atgggattgt aacggcagcc tttgggcaat
    14941 ttttaccaac agtcttattg gattcggtga catttgctgt taatgtgcac gcgtccttac
    15001 ttcctaaata tcgtggtggc gctccgatcc attatgctat tatcaatggt gacaaggaag
    15061 ctggagttac cattatggag atggttaagg agatggacgc tggggatatg atatcaagcg
    15121 caagccttcc aattttagat actgataatg ttggtaccat gtttgataag ctggccattc
    15181 taggacgaga tttattattg aaaaccttgc ctgattactt gtctggtgac ctaaagccag
    15241 ttcctcaaga ccatagccaa gccacctttt ctcccaatct ttcagcagaa gaagaaagac
    15301 tggactggtc aaagccagca agagaggtgt ttaatcatat cagaggaatg aacccttggc
    15361 cggtggctca taccttatta gatgggcagc gcttcaaaat ttatgaggct gaattggctg
    15421 aaggctctgg atctgccggg caaatcatcg ctaaaactaa aaaagcattg gtcgtagcag
    15481 caggtgaggg ggctctatcc ttgacgctcg ttcaaccagc aggcaagcca aagatgccta
    15541 ttgttgactt tttaaatggt attggcagaa gcctagaggt gggtgatgtc cttggcgaat
    15601 gattggaaaa aatcagctag aggacaggcg ctgcttatcg ttgaggatat ttttgatcat
    15661 ggagcctatt ctaaccttgc cttgaagcac cagctggcga atcagttttt aagtgataag
    15721 gacaaggctc tagtcacaga gattgtttac gggactatct ctaggaagat aaccctagaa
    15781 tggtatctgg ctcactatat tgaggaccga gacaggctgg ataaatgggt ctactatctc
    15841 ttgatgctta gcctttatca gctggcttac ctagacaagg tgcctgccca tgctattgtc
    15901 aatgatgctg ttaaccttgc caaggctcgt gctcgtggca ggggagcaga caagctggtc
    15961 aatgctgttt tacgtcagct tacgaccaac cctctgccag atatgaccag catcaagcga
    16021 aaaaataaat actatgctgt tgcttactca gtaccggtct ggctagtcaa aaaattgatc
    16081 gaccaatttg gcgaggagcg agctgtagca gtcatggaaa gtctttttgt gagaagcaga
    16141 gccagcatac gtgtcacaga tctggcaaag cttgatgaga tcaagcaagc aacaggatca
    16201 gagcaatcat tacttgctag gactggcctg accaagagag ctggcaattt tgctgccagc
    16261 agttatttca tcaatgggga cattacgatc caagatgaga ccagtcagct agttgccccg
    16321 acgctggata ttcaagggca ggaaatgatt ttagatgctt gtagtgcacc cggagggaaa
    16381 acagctcaca ttgcctctta tttgacgagc ggcaaagtag tggcccttga tttgtatgag
    16441 cacaagctgg ccttagtgaa tgaaaatgct aagcgtctag gggtagcaga tcggattgaa
    16501 actaaggtgc ttgatgctag agaggttcat aagcattttg cgaagaacag ctttgataag
    16561 attttagttg atgctccctg ctctggtata ggcctcatca ggcgtaagcc agatattaaa
    16621 tacaacaagg aagggcagga cttccagcaa ttgcaggaaa ttcagctgga gatattgtct
    16681 agcgtttgtc aaacgctgcg aaaaggtggt ataataacct atagcacttg tacgattttt
    16741 gatgaagaga atttccaagt tattgacaaa tttttacaac gtcatcctaa ttttgaacaa
    16801 gtaacactca agcatgcaca agcagatatt gtcaaggacg gttgtcttat gattacacca
    16861 gagcaatacc agactgatgg cttctttatt gggcaagtca gacgagtctt gtagtattta
    16921 ggaggagact gacctagtca gaaaagatta tatgaagatt tcattaaaaa ccgatattgg
    16981 gcaaaagcgc tcaaacaatc aagattttat caacaagttt gataataaaa aaggcattac
    17041 ccttgttatc ctagcagatg gtatgggagg tcatagggca ggaaatattg ccagtgagat
    17101 gaccgttaca gacctaggta gagagtgggt taagacagat tttactgagc ttagtcagat
    17161 caaggattgg ttgttaacaa ccatcgaagc agagaaccaa cgtatctacg acttgggaca
    17221 atctgaagac tataagggaa tgggaacaac cgttgaggca gttgctctag tagattctaa
    17281 tgcgatttac gctcatattg gcgactctcg tatcggcttg gttcgtgagg gaaattatag
    17341 ccttttaacc agtgatcatt ccttggttaa tgctctagtg aaggctggtc agattaccga
    17401 agaggaggct gctagccacc cacaaaaaaa tatcatcaca caatctatag gtcaagcttc
    17461 accggtagag ccagacttag gtgtcaaggt tttagaaaag ggcgattacc tagtgattaa
    17521 tagtgatggc ttaaccaata tgattgctaa tgaggagatt gttgacatat tatgtcaaga
    17581 catcagcctt gatgagaaaa atcaagcctt gattgacctg gcaaaccaaa gaggaggcct
    17641 agacaacatc accgttgctt tggtgcataa ggaaagcggg gaagcagaat gattcagatt
    17701 ggcaagctat ttgctggtcg ttatcgcatt ctaaaatcta taggccgcgg tggtatggcg
    17761 gatgtttatt tagcaaacga tttgattctg gataatgagg acgttgccat taaggtcttg
    17821 cggaccaatt atcaaacaga tcaggttgct gttgcgcgtt ttcaaagaga agcgcgagcc
    17881 atggctgaat taaatcaccc caatattgtt gccattcggg atataggcga ggaagacgga
    17941 cagcaatttt tagtaatgga atatgttgat ggctctgatt tgaaaaaata cattcaggat
    18001 catgcgccat tatctaacaa tgaggtggtg agaatcatgg aagaggttct ttctgccatg
    18061 actctggccc accaaaaagg aattgttcac agggatttaa agcctcaaaa cattcttttg
    18121 accaaatcag gtgttgttaa ggttacagat tttgggattg ccgttgcctt tgcagagacc
    18181 agtctaaccc agacaaattc tatgctagga agtgtgcatt acctctcacc tgagcaagcg
    18241 cgtggttcta aagcgacgat tcaaagtgat atttacgcga tgggaattat gctctttgaa
    18301 atgctaacag ggcatattcc ttatgatggc gatagcgctg tgacgattgc tttgcagcat
    18361 tttcaaaagc cgctgccctc tatcattgat gaaaatccta atgtgcctca agccttggag
    18421 aacgtcgtta ttcgggctac tgccaaaaag ctaagtgacc gttatcgctc gacctttgag
    18481 atgagcaggg acttgatgac agcccttagc tataaccgca gtcgtgagcg taaggttgtc
    18541 tttgatgatg tcgaaagcac aaagcccttg ccaaaggtaa caccgactcc tgtaacagca
    18601 cctaaggtat caaatgctag tcaggcatct gcggcagctg atgctagact tgagcagact
    18661 agccagatgg atactctgca aaagcctcaa aaaaagaaaa aaaatgggcg ttttctagga
    18721 acactcttaa aaatcttgtt ttcctttttt gttgttggtg tggctctttt tgcttatttg
    18781 gtcttgacca agccaactac ggttaaggtt cctgatgtga caggctctag tctcaatgct
    18841 gccaagcagg tcttggagga ggcgggacta aaggtcggta aggtccatca gattgaaagt
    18901 gacacagtta gtgaggatca ggtggttaag acaaatcctc aagctggctc agctaagcga
    18961 aaaggctcca gcgttgacct ttacctttcg atcggaaata aaggctttga gatggaaaat
    19021 tataagggac aggattatca agatgtgatg accagtctga ccgagaccta tggcgtacca
    19081 aagtcaaaaa tcaagattga gcgtatcgtg acaaatgaat accctgaaaa caccgttatt
    19141 agccagtctc caagcgcagg agaaaaattt aacccagctg gtaaatccaa gattaccctc
    19201 agtgtagcag tgggtgatac ggtcatcatg ccaatggtaa ctgagtacag ctatgcagat
    19261 gcagtcaata cactaacagc tttaggaatt gatgccgcaa gaatcaaggc ctatgtacca
    19321 agctccagct ctccgacagg ctttgtgcag gtgagctccc caagctcaaa ggcggttgtc
    19381 agtgggcaaa caccgtatta tggtacccag attagccttt ctgaaaaggg tgatattagc
    19441 ctctacctct accctgagga gacacgtgca tcaagcagct catcgagctc tgatacctcg
    19501 gctcctaatc catcagctgg agatacaaca gactcaagca gtcataccga attaggtcaa
    19561 aatgacgctg ttacaacacc gtaaacgtaa ataggatata gaatatctgg cttgcccata
    19621 gttgctaagc taggtattct tttttactag aatgccactc aagggtgaat ttttgcttaa
    19681 tttttgataa aatgtcaggg taatggaagg agtctaatga aaaaatttca attctttctg
    19741 cttgttgaat gcatgctgct ggctatgggg attatgacca ttttggccaa cgacttatca
    19801 agctttattt taattttggt cttgatttta ttggctctgc gtttttataa tcaagatacc
    19861 cgcaatagct ttttgctaac agttagctta ttgcttttat tcttaatttt tatgctgaac
    19921 ccttatatta ttatggcggt tctgttggga attgtgtatg tgattatcaa tcacttttca
    19981 caggtaaaaa agaagaatcg atttgccctc attcggtttg cagaggaaaa aatgactgtg
    20041 cggcaggtca aaaatcaatg gcttggcgca gctaactatg aaagtgacta ttattccttt
    20101 gaggatatca atattattcg cgcctctggc aatgatacga ttgatctgac aaatgtgatt
    20161 gtaactggaa tggataatgt tatcattatc agaaagatct ttggcaacac aaagattcta
    20221 gtgcctattg atgtggccgt taccttagag gttagctcta tctatgctag tgttgatttt
    20281 tttgagcttc aagaatacga tttacgaaat gaatccatca ccctaggaga gactgaggac
    20341 agcagcttaa agaaggttaa gattattgta tccaccatag caggaaatgt tgaggtggct
    20401 agacgatgaa aaaaaggtat tatgctttgg tctggcttta ttcgaccatc accattttat
    20461 caattgtttt tgttgtgatg gataatctgg ggatcacttt tgattacctg cgaagccatt
    20521 tatggcagct agagcgcttg gtgttttcag ttgtgctgct tatcatctct gtaaccttgc
    20581 tgctgctttt gctgtggatt attttagatg ataatagcaa gcgaagcatc aataaaaatt
    20641 tacgcaggat tctcaacaat caaagaattc atttggagga gacctccgaa atcaacacga
    20701 atttgaccag actttctgcg aaaatgtctc acataacaac caatatccag aaaaaagaga
    20761 atgcttatat tttagatagt caaaaaattg ttcaacagga gcgtaaacga atcgctagag
    20821 acctgcacga cactgttagt caagaattgt ttgcttcgtc gatgattttg tcaggggttt
    20881 ctatgagcct agatcagatg gataaggagc agctgaagca gcaattagtt actgttgaag
    20941 ccatgctgca aaatgctcaa aatgatttac gcattttatt attgcacctg cgcccgacag
    21001 aattggcaaa tcgtagcctg tcagagggct ttacgatgat tctcaaggaa ctaactgata
    21061 aaagcggcat tgaggttgtc tataaagaaa atattggcac tctgccaaag gccatagagg
    21121 ataatctctt taggatcgcc caggaattta tcagcaatac cctcaagcat gctaaggcga
    21181 gccgccttga ggtgtacctg aaccaaacac caacagagct gcagctaaaa atggttgata
    21241 atggggttgg ttttgacatg gatcaggtta gggaattaag ctatggcctt aaaaatattg
    21301 aagatcgtgt gaatgaccta gctggaacgc ttcgtttgat tagccaaaaa ggaaagggcg
    21361 tttcgatgga cattagactg ccacttgtga tgggagatga agatgagtaa tataaccgta
    21421 atattagttg atgaccatga aatggtccga atgggcttaa agagcttctt aaatttgcag
    21481 caagatgttg atgtcatagg tgaggcttct aatggtcgtg agggagttga gcttgccctt
    21541 gcattgagac cagatgtcgt ggttatggat ttggtaatgc ccgaattagg aggtgtggag
    21601 gcaaccttgg aaatcctatc caaatggaag gaagcaagag tgttggtgtt aacctcttat
    21661 cttgataacg aaaaaattta ccctgtcatt gacgcaggag ctaagggcta tatgttaaaa
    21721 acatcaagtg cagctgaaat cctaaatgct attagaaaag ttgctaaggg tgagcttgcc
    21781 attgaaacgg aggttgacaa gaagattaag gcacatgatc agcagcctga tttacatgaa
    21841 gagctaacag cgcgtgaata cgatattctg catttattgg ctaaaggcta tgacaatcag
    21901 accattgctg atgagctttt tatttccttg aagacagtta aaactcacgt gtcaaatatt
    21961 ttagccaaat tgcaggttga tgatcgtact caggctgttg tatacgcttt ccgacaccat
    22021 ttagtgcccc aagatgatca ttaatgctat aatagtatca ttgcaatgga ggaaagtatg
    22081 gacgcaaaat taaagtataa ggccaagaaa atcaagatgg ttttctttga catagatgat
    22141 accctgcgcg taaaggacac aggctatatg ccagagtcta tccagagggt tttcaaagag
    22201 ctcaagaaaa aaggaatcct aacaggaatt gcttcgggcc gcgccagata tggagtgccc
    22261 aaggaggttc aggatttaga ggcagattat tgtgttaagc taaacggtgc ttatgtgaag
    22321 gacaatcaaa aaaacattat ctttcaggcg cctatcccgg cagacaccgt tgtagcctat
    22381 aaagaatggg ccaatacagt cggtatcgat tatggcatgg caggacgtca caaggctgtc
    22441 ttatcagctc gtaatgagat gattagtgat gctattgata aggtttactc cacactagag
    22501 gtatgcccag attacaatga gcaccacgat gtctatcaaa tgtggacctt tgaggacaag
    22561 ggagatgacc tgcaattacc tgctgaattg gctgagcagc ttcgcctggt aaggtggcat
    22621 gatcactcct ctgatgtggt cctaaagggc acctctaagg ctttaggtgt atcaaaggtt
    22681 gttgagcatt taggcttaaa acctgaaaat atcctggtct ttggtgatga gctcaatgat
    22741 ttagagctat ttgattatgc tggcatcagc attgctatgg gggtttctca cccacaatta
    22801 caagaaaaag cagattttat tactaaaaca gttgaagaaa acggcatttt atatgccttg
    22861 gaggaattag gtttgattga taaagaatta cattttccgc agctagactt ggctagctat
    22921 gaaggaccaa gagtggtgat gaaaacaaat catggtgagc tgacattggc tttatttcca
    22981 gagcatgccc caaaaacagt tgccaacttc ttaggcctag ctaaggaagg ctactataat
    23041 ggtgttattt tccatcgtat tattgcagat tttatgattc aaggtggaga tccgactggc
    23101 actggaatgg gtgggcaatc tatctatggc caaagctttg aggacgagtt ttcagaggca
    23161 ttgtataacc ttcgcggagc cctttcgatg gctaatgcag gcccaaatac aaacggtagc
    23221 caattcttta tcgtccagaa tgcaagcctt ccttattctc aaaaggaatt agaacgtggt
    23281 ggctggccaa aggacattgc agcagcctat gctgaacatg ggggcactcc tcaccttgat
    23341 cgtcgccata cagtgtttgg tcagctggct gatgaagcct cctatcaggt cttggataac
    23401 attgctgctg ttgaaacagg ggcacaagat aagccaaaag aggacgttgt cattgagacc
    23461 atcgaggtat ttgattgatg aaaattggcg ataagctgca tgggaccatt acaggaatca
    23521 aaccctatgg agcctttgtt gcccttgaaa atgggacaac aggtctcatt catatttcag
    23581 aaattaagac ggggtttatt gataatattc atcagatcct aagacttggt gaggcggttt
    23641 tagttcaggt cattgactat gacgaataca gtcataaggt cagcctgtcc ttgagaactt
    23701 tggaggagga aaagcatcat gtgtcaagtc atcatcgctt ttcaaacagc cgttataaga
    23761 ttggctttaa gcctcttgaa gccagcttac ccaattggat tgaggaaggc ttagaccact
    23821 ttaagcagga aaaatcgtaa acagacttgg aaacataaaa aaccgagaaa cagctatatg
    23881 aactgttcct cggttttttg ctatcagctc tagaccagtc atcttactta tctcaaagct
    23941 atcttcaaaa aaagccaatt gtaattgcca atcctctttg aatacttagg ctactagctt
    24001 gagtattctt agcttgtggt aaaagcagct agaatattga cagatcaaaa gcttgtttcc
    24061 aagaagctag gagctcttgg gcgcttaagc ttgatatgcc tatattcact gttagaaagg
    24121 aatcaaagta agcatttttc cataggctag ctgactggcc tttaagtggt ggctaagtaa
    24181 gagcgatgat gtgtgcttaa aagcttgttg cagctgatgg gactggacta gcgctgatgt
    24241 gttctgcttt ttattctaat caaactgata aagggcagta gacaggtatc gctcaccatt
    24301 atctggtaat atagctaaga cctttttacc ttttccaagc tccttagcgg cttgaatagc
    24361 agcataaaca gcagctccag aagaaatgcc tacaagaaag ccctccttag ccccgattga
    24421 ccgagcagta gcaagggcag cctctgacgc tactcgaatg atgtggtcat aggcctttgt
    24481 atctaaggta tttgggataa agccagctga aatcccttga atcttgtgcg aagaaggctc
    24541 ttcgccagat aagacggcag attcatctgc ttccacagca tagatagaaa tatcaggatt
    24601 aaccgccttt aaggcatgcg caacaccaga aatagtgcca ccagttccca caccagaaac
    24661 aaaggcatca agtccttttt ctccaaaaac ctcgataatt tcttgccctg ttgtctcctc
    24721 atggaccttg ggattggcag gattgtcaaa ttgtgagggc atccaagcac cagtctctct
    24781 ggcaatctct tctgctttag caatcgcgcc tttcatccca tcactacccg gggtcaaaac
    24841 aagctctgct ccgtaagcct gaatgatttg acgtctttca atactcattg tctcaggcat
    24901 tacaataatc actcggtagc cttttgcagc cccaacccag gataagccaa tccctgtatt
    24961 gccactggtt ggctcaacga ttgtatcacc tggcttgatc atgccggctt tctccgcagc
    25021 ttcaatcatt gcaagtgcga tgcggtcctt gactgaagag cctggattaa aagcttctag
    25081 cttgacataa atatcggcag cctcctctgg actggtgttt ctcaatttaa taataggggt
    25141 tttcccaacc aactctgtaa tgttgtgata tagctttgac ataggtcctc ctttttatcc
    25201 ttgtatcaat acatgcttat ataaaagtat atagctgata atcgacaaag taaaatagcc
    25261 atttactatc gtagtgataa ggagacgcta tcactgttca tgctaatcgg caggcaaaac
    25321 agggacctca atcctttgcg attcgatctc ttcaaaggaa accttgccat gataatgctc
    25381 aatcaatgcc ttagaaatac tctccaagcg ctcaggatca aagtaaatag ctgttctgac
    25441 gacatcagaa aattcggtat tcatttcaat caatccttct tgatccagaa aattaggata
    25501 gatttggtat tgagggtagg tgaggctgat tgctagtcca gtttgttttt ttacctcaac
    25561 cacctttaaa gcctgaatag ctgctgcagt cacgccggag taagcacgaa taagtccccc
    25621 agctcctaat ttaatacctc caaaatagcg agtcacaaca gctacaagat tggttaattc
    25681 ctgcctttct aagacagata gcatgggaat accagcagtg ccagacggct caccatcgtc
    25741 gcttgaccgc ttggtttgcc ctttatctcc gatgatcata gcagagcagg aatgattggc
    25801 cttatagtgc ttttttttga tatcagcaat aaaggctctg gcctcttctt ctgtgtagac
    25861 gcgtttgatt tggcaaataa agcgagattt tttgatgctt tcctcaaaaa gcccatcagt
    25921 cataatagtt ttataatctt ccataagaaa attttacaaa aaatgctgat atttagcaaa
    25981 ataattcgga taataaggta tggagaatat cgaaaattac tatggacgtc ttttacccga
    26041 aaggcaatgc ccaaaggctg tttctgtctg ggcttgcagc ttacaaagca tgatcgctaa
    26101 aaaaggaaca ttatactgcc aacgctgtag cagcttaatt gagaaagctc atcagctacc
    26161 tagcggtgct tactattgta gagcctgtct cgtttttggt cgaaaccaat ctgatcggcc
    26221 cttgctctat tttccaccgg ctccttttcc aaaggcacat tatctgaggt ggcaaggaca
    26281 gctcacaaca tatcagggag ctgtctctca tcagcttact aaccatgtta agctcaagca
    26341 agacacactg gttcatgccg ttaccggcgc tggtaaaaca gagatgatgt atgaagccat
    26401 tgcagcagtt gttgataagg gtggctgggt ctgcattgct agtccacgag ttgatgtctg
    26461 catagagctt gaaaaacgac tatcgcggga cttttcctgt caggtctgtc ttatgcatgc
    26521 tgagtcagag gcttatcata gaagtcccat aatcattgcc acaacacatc aattgatgac
    26581 cttttaccat gcttttgatc tgctcattat tgacgaagta gatgcctttc cctttgtcaa
    26641 taatcgtcaa ttaaaccatg ctgctcatca ggctgcaaaa gcagatgcag tgacagtata
    26701 cctaacagca acctctacaa aagacttaga gcgcaaggtc aagcaaaaag agcttgtcaa
    26761 attgacattg gcaagaagat ttcatggcaa gcccttagtt gttccaaagt atcaaagatt
    26821 attctccctt ttagaggcta tcaatcgcgg gaaattgcct agaaggttca tcaccctagt
    26881 caaaaaacaa agggcaactg gctatcctct cttaatcttt tttccgctta ttgagctggc
    26941 tgagcaatgc tgtcagctgc tccaaaagta ttttcctaag gaaactattg cccatgcttc
    27001 tagtcagtca tcaaatcgaa tgactatcat tgagcaattc agacaaggac aaatcactat
    27061 acttatatca acaaccattt tggaaagagg tgtgaccttt ccgaccgtag atgtctttgt
    27121 cttattagcc aatcatcgcc tttacacaag cagcagtctt attcaaattt caggtcgcgt
    27181 tgggcgctct ttggaaagac cggaaggaca ggtgctattt tttcatgatg gtattagcca
    27241 ggctatgctc aaggcagtgc gggagataaa ggacatgaat caaaaagggt atcaaaatga
    27301 actgtctact ctgccacaat aatagtaaag atagcttgtc tatcacagca attctgttgt
    27361 taagtcctaa taaggatctt atgtgtgatg cctgtcagcg tcatttttgt aggattactc
    27421 agccaacctg ctctaattgc taccagtatc gttatgaggg cgcctgccag gattgtattg
    27481 cctggaaaag gcaaggctat caggttgatc atcagagcct ttaccaatac aacaccgcaa
    27541 tgaaggatta tttcagccgt tacaaatttc aaggagatta tgttttacgc agtctttttg
    27601 cgcatgagct agctaagcac attaaaaagt attataaagc ctatactttg gttcctgtac
    27661 ctgttagcaa gcaaagatat gatgaaaggg gctttaatca agtaacagct attttagaat
    27721 atgccaacct agcctatctt gatctatttg agcgaaccga tgatactaga caatcaagca
    27781 aaacaaaaaa agaacgcctg cagctaaata accgttatcg actcaaaaag ggggcagtcc
    27841 ttccaaggaa aatcttgtta attgatgata tctatacaac cggtagtact ataatgagtc
    27901 taaggcagga gcttattagg catggttgtc aggacatcaa aagtctctct attgcacgat
    27961 aaaacttgca aattttcatg aaaacggcta taatagaact aaagaaagcg ttttaaacgc
    28021 aagaaagagg tactcttatg attaaattca gtattcgtgg agaaaacatc gaagtgacag
    28081 aggctattcg cgattatgta gaatcaaagc ttactaagat tgaaaaatat tttgttgaag
    28141 agcaagaaat agatgcgcgt gttaatttaa aggtttatcg tgaaaagact gcaaaggttg
    28201 aagtcactat tccacttggt tcagtaacac ttcgtgcaga agacgtttca caggatatgt
    28261 atggatctat tgatttagtc gttgataaaa tcgaacgtca aattagaaaa aataaaacaa
    28321 aaattgccaa aaagcatcgt gaaaaaatgt caactagtca agtgtttact agtgaatttg
    28381 aagcagagca agcagaagaa actccagaaa tcaaagtggt ccgcactaaa aatgtgaccc
    28441 tcaagccaat ggatgttgaa gaagctcgct tgcagatgga acttctaggg catgatttct
    28501 tcatctatac agatgctgaa gatggggcaa caaatgttct ttatcgtcgt gaggatggcg
    28561 acttaggact tatcgaagca aaataatttg aaaagcaaga ggcatctcac ctcttgtttt
    28621 tttgcccttg acaattaaag gtaagatatc gtatactaat gaggctgtcg gcgagcacta
    28681 gctcaagtta atgaaaaaag gtaaaaaaa
//
LOCUS       DARYSY010000026        25913 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYSY010000026 DARYSY010000000
VERSION     DARYSY010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25913
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..128
                     /locus_tag="TVR04_001035"
     CDS             <1..128
                     /locus_tag="TVR04_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1269734.1"
                     /translation="YHSLDELEQAITEYIFYYNNKRIKTKLKGLNPVQYRTKSFQ"
     gene            266..535
                     /locus_tag="TVR04_001036"
     CDS             266..535
                     /locus_tag="TVR04_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1269735.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            532..951
                     /gene="ruvX"
                     /locus_tag="TVR04_001037"
     CDS             532..951
                     /gene="ruvX"
                     /locus_tag="TVR04_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1269736.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDRIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            961..1260
                     /locus_tag="TVR04_001038"
     CDS             961..1260
                     /locus_tag="TVR04_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1269737.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            1813..3372
                     /locus_tag="TVR04_001039"
     CDS             1813..3372
                     /locus_tag="TVR04_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1269738.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSIQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLVHYVTGIQKVALGFTAIYYLLSVSLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPMTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVLSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRTVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLAEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAAYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            3468..5666
                     /gene="nrdD"
                     /locus_tag="TVR04_001040"
     CDS             3468..5666
                     /gene="nrdD"
                     /locus_tag="TVR04_001040"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1269739.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPPHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHLADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDITSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKDYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            5772..5918
                     /locus_tag="TVR04_001041"
     CDS             5772..5918
                     /locus_tag="TVR04_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269740.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            5946..6881
                     /locus_tag="TVR04_001042"
     CDS             5946..6881
                     /locus_tag="TVR04_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1269741.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMAGFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLADGRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            6894..7388
                     /locus_tag="TVR04_001043"
     CDS             6894..7388
                     /locus_tag="TVR04_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1269742.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEELLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREILVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            7398..8012
                     /gene="nrdG"
                     /locus_tag="TVR04_001044"
     CDS             7398..8012
                     /gene="nrdG"
                     /locus_tag="TVR04_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1269743.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(8471..9202)
                     /gene="yaaA"
                     /locus_tag="TVR04_001045"
     CDS             complement(8471..9202)
                     /gene="yaaA"
                     /locus_tag="TVR04_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1269744.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSISIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHFKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSS
                     EFKDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETDYYYIKKES"
     gene            9632..9835
                     /locus_tag="TVR04_001046"
     CDS             9632..9835
                     /locus_tag="TVR04_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1269745.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            9837..10289
                     /locus_tag="TVR04_001047"
     CDS             9837..10289
                     /locus_tag="TVR04_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1269746.1"
                     /translation="MIFSDLSVLLTQKSQLAYAKRLKYMGFFALCLGGLFLLLAFDVR
                     LTSFAQGMLVGLGSGSLLLGVRAFQIAFNPQRLRASYIKAYDERHQVVIKLAAVSTLI
                     LLVVLIIGGLCLNVFWGLVLGFRVFLEICLYTILLGFLGIKLLLEHVI"
     gene            10299..10973
                     /locus_tag="TVR04_001048"
     CDS             10299..10973
                     /locus_tag="TVR04_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1269747.1"
                     /translation="METKHSVVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            11003..11440
                     /locus_tag="TVR04_001049"
     CDS             11003..11440
                     /locus_tag="TVR04_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269748.1"
                     /translation="MKNDHWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKTQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYIMIRAWVSKHM"
     gene            complement(11663..12436)
                     /locus_tag="TVR04_001050"
     CDS             complement(11663..12436)
                     /locus_tag="TVR04_001050"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1269749.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSVQRSKEIADQLQ
                     LAYTQSHQELIDQVDFIILGIKPQLFEAVLSSLQFKQPIMSMAAGISLDRLAQLTSTD
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDAFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(12520..13587)
                     /gene="pepA"
                     /locus_tag="TVR04_001051"
     CDS             complement(12520..13587)
                     /gene="pepA"
                     /locus_tag="TVR04_001051"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1269750.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTIRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAANLPAVSDIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKRLDRSTVDLIKKY"
     gene            13919..14266
                     /locus_tag="TVR04_001052"
     CDS             13919..14266
                     /locus_tag="TVR04_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1269751.1"
                     /translation="MAEIVSFCSSLLFPFCDKIKGMSGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQKVLAELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYR
                     YHKGSIDFKEDLT"
     gene            14263..14580
                     /locus_tag="TVR04_001053"
     CDS             14263..14580
                     /locus_tag="TVR04_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1269752.1"
                     /translation="MIIPKSKDELARLIETEPRLVLFFTADWCPDCQYIYPVIPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            14595..15221
                     /locus_tag="TVR04_001054"
     CDS             14595..15221
                     /locus_tag="TVR04_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1269753.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVVRVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPDPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDRAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKDSFGMMCSPRELALPNAPQKRGIIELGDAAVVGEAFDPAKHWQS"
     gene            15815..16210
                     /locus_tag="TVR04_001055"
     CDS             15815..16210
                     /locus_tag="TVR04_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1269754.1"
                     /translation="MYNKVILIGRLVAKPELTKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            16663..17637
                     /locus_tag="TVR04_001056"
     CDS             16663..17637
                     /locus_tag="TVR04_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1269755.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHKAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFKEGKNLTITTKNAHGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNVDSLTPAVFTAVTDPVSAGLVDTLAKPGGNMTGSIDATNVENQIDLLTKAF
                     PQARTVGIFYNSSEVNSEVQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLVSQVD
                     AVYLPTDNTVASTAATIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            17655..18617
                     /locus_tag="TVR04_001057"
     CDS             17655..18617
                     /locus_tag="TVR04_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1269756.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAHGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLNKAGYKVIKKGIATSNDVQDTAASLMRAV
                     DAFFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            18732..19616
                     /locus_tag="TVR04_001058"
     CDS             18732..19616
                     /locus_tag="TVR04_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269757.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFVGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVILLLALLMKTQLGLALR
                     STGDNGPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            19625..20428
                     /locus_tag="TVR04_001059"
     CDS             19625..20428
                     /locus_tag="TVR04_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1269758.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDVEEGDFISVIGGN
                     GAGKSTLMNTLAGTLSLDQGDILLEGKSIQHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMAALEKPKVLLLDEHTAALDPKTSAMVMTLTRQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKGEEKANLTVDHLMTLFHQNSGHMLLDDALVLG"
     gene            complement(20527..21531)
                     /locus_tag="TVR04_001060"
     CDS             complement(20527..21531)
                     /locus_tag="TVR04_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269759.1"
                     /translation="MFRRNNIIWRSLLKHLLLLATCLGSLSLGNILSKADSQDHLRVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLYPDLRSTGQ
                     ETQSSTPPAPSYQTRSSQASHTANTYRTTTPYSSYRRYSDAQILANIKAELEKSDYDA
                     IKHFKDDFLNRLHSQEIKLSPFRDRSKIPALLFRELQHYLKLHPEMIYRLDGINLSPD
                     TADSFVNRLANAYSLDNMLSILQEAKAYGQGIINTIAKREEAKAILTEHRNTYRGRNQ
                     HVGDDYYSIAFHEIDEAITVQQLNKAIAIVENEAYRVRNKSFDYNGRHHGFFTLRKIS
                     "
     gene            complement(21820..22461)
                     /locus_tag="TVR04_001061"
     CDS             complement(21820..22461)
                     /locus_tag="TVR04_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEL1269760.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTEVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIFFLNKRFKSIKEAYQADNNILDRSIFEDELFLTLNYKNGNVTKTELE
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFEKMLERIEKRGRRFEQVDDNPDLEAYY
                     YQVHGEYPTWYERYDVSPKMRIDGNKLDFVQNPEDLATVLQMIDEKLKTLDLL"
     gene            complement(22482..23459)
                     /gene="dusB"
                     /locus_tag="TVR04_001062"
     CDS             complement(22482..23459)
                     /gene="dusB"
                     /locus_tag="TVR04_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1269761.1"
                     /translation="MIRLNSSFKIGSVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLAHVSRAITKIPFIGNGDVRTVQDAA
                     FMIEGIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFTKKLDIAREHLKRLIR
                     LKGETIAVREFRGLAPHYLRGTAGAAKIRSAVSRANTLAEVETIFAQIH"
     gene            complement(23446..24318)
                     /gene="hslO"
                     /locus_tag="TVR04_001063"
     CDS             complement(23446..24318)
                     /gene="hslO"
                     /locus_tag="TVR04_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1269762.1"
                     /translation="MDKLIKTISVSGAFRAYVLDCTETVRAAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGNGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPEASDEEISRYEKRIQEMPAISTLLASKNHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLAMLNEDQGAEIVCQFCGTKYQ
                     FDQADLEVLINDKT"
     gene            complement(24568..25776)
                     /locus_tag="TVR04_001064"
     CDS             complement(24568..25776)
                     /locus_tag="TVR04_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1269763.1"
                     /translation="MVSFHLKHIQALHNLSQLPVLVLSQNLELLQAYDDEERRFPYYE
                     LIKTLDIPSNTELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLK
                     RYPDKSKKELVGYISTIPHFPASHIRSLLIAVDAFFDTSFEMSCQQSINDLLEEAQLI
                     WEDPHIIANLELENTPSFHVPTVLNYLNHIIDLVKLGNTELLKKEINCIPASDVISSS
                     ISALRAEKNLSMVYFTKLLELSFTENTDVAKNYERIKHFMNLTEKAPDILKVLQIRAA
                     AIISLSESLINKSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKM
                     YSSISLQTYILKEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDY
                     LAHYQQSITK"
BASE COUNT         7399 a         4772 c         5938 g         7804 t
ORIGIN      
        1 cctaccactc actggatgag ctcgaacaag caatcactga atacatcttt tactacaaca
       61 ataaacgaat caaaactaaa ctaaaaggac ttaatcctgt tcaatacaga actaaatcct
      121 ttcaataatt attcgtccaa ctttttgggg gcagtacacc tagcagatct ttttttaata
      181 tcctaacaaa tctgaattct tgtttattca ataaaaataa gctataatag agcgtagcac
      241 ttaaagttag aaagaaggtg taagtatggg atttacagat gaaacagtcc gctttaattt
      301 agacgatggt gataaaaagc agattagcga aacgctgaca gcagtttatc attcactaga
      361 tgaaaaaggc tacaatccaa ttaatcaaat tgtaggttat gtactaagcg gggacccagc
      421 ttatgttcct cgttacaatg atgctcgcaa ccaaattcgt aagtatgagc gtgatgagat
      481 cgtagaagag cttgtccgct attatttgca aggaaatgga atagatatta gatgagaata
      541 atgggacttg atgttggttc taagaccgtt ggtgtggcca ttagtgatcc acttggtttt
      601 actgcccaag gactagagat tattaagatc aatgaagata aacaggattt tggctttgat
      661 agattagctg agcttgttaa gcaatatcag gttgatcggt ttgttattgg cttgccaaag
      721 aatatgaata acactagtgg cccacgtgtt gaagcaagta aggcttatgg agataggatt
      781 gaggagctct ttcacattcc tgtttcttat caagacgagc gcttgacaac tgttgaggca
      841 gagcgtatgt tgattgagca ggcagacatc agtcgtggta aacgtaaaaa agtaatcgat
      901 aagctggctg cgcagctgat tttacagaat tatttagatt gtaactatta aggagaacag
      961 atgacacata atcatgatca cgaacacgaa gtcattacac ttgtcgatga gcaaggaaat
     1021 gaagcattgt ttgaaatttt attaaccatc gatggacgtg aagaattcgg taaaaactat
     1081 gttttgctag ttcctgctgg ctcgcaagag gatgaatcag gagaaattga aattcaggcc
     1141 tattcattta cagaaaatga agacggaaca gagggtgatt tgcagccaat tccagaggat
     1201 tcagatgctg agtgggatat gattgaggaa gtctttaata gcttcttaga cgaagagtaa
     1261 aaaacctgaa gtattagctt taaaataaca aatagcctag attcttaatg ctggcagcat
     1321 gggttttagg ctatttttat ggtttatcag acagtaggag cgatacctat ttttatgatc
     1381 tccaaatagc ctactgttaa tagtgttttt agagttttgt agatgttgca atggcctgtg
     1441 atttcgttga agttacttgc tattgtcttt ttttagttta agccttaaca aagctgtggc
     1501 taggctatag gaaatgactc aacttagcac agcataagcc gctcattttg aataagtaac
     1561 gaaatagcca ataactgctt tttgcttaaa gccgatggtt actgttagtt ttctgagttt
     1621 catttcgaat aatcttaatg gggtgatttt atcaaaaggc tcagtcaaga agaaaaaagc
     1681 tttctaaagc attataggct aaagacactg caccgcttta aagagctgct gacttatgcc
     1741 agcatttgtc ataaattgac taaataatag attttgctat acttgtaata tgacatgtca
     1801 aggagaaaca cattgagtca attacatcaa gaagttatgc tggaaaaggt caattatttg
     1861 gtgaaggacc acccatcgtc acatacaact aagtatgaca tgaaggtccc tagtttatat
     1921 aaattttata tctttttctt tagcatcata gcgagcttac ttacggttgc ggttcctttt
     1981 tttgcagata ctgcaaatag cattcagtca caaaatttat acatcggaat gatgttgact
     2041 aaaggtcaga ttccatatag tgatttgttt acaacaggag gctttctgtt ttttgtgctc
     2101 atagctttga gttatcactt gggaacaacg gtatggttgg tgcttgttca agcgctgtgc
     2161 ttttatttga caggtgttta tttctataaa ttagtccatt atgtgacagg tattcagaag
     2221 gttgctttag gttttacagc tatctactat ctgttgtctg ttagtcttgg atttggtggc
     2281 ttatatgcga tccagcttgc cctgcctttt gtcttggtat cgctttggtt tttgaccaag
     2341 tattttgctg gcttggtaaa ggacgaggcc tttattctct ttggctttgc agcggcaata
     2401 gccatgctaa ttgagcctat gacgcttctt ttttggctgc ttgcttgcat tgcgattatt
     2461 gcttataatg tgtctcaaaa gcatttcgct cgaggctttt atcagctgtt agcagctatt
     2521 tttggaatgc ttttggtgtt ttatacagca ggctatttta tcctcaatct acagattttg
     2581 agtccttatt tggagcaggc gcttgtttat ccgtttagtt attttgtgac aggtgattta
     2641 tcgctgattc tcggtttaac agtccaatta ggacttgttc ttggcttagg actgttaacg
     2701 gggctgctga cgtttatgaa gcagcctaag ctagagtctg atcttgctat gaaatggcta
     2761 ctagtctttg ttgtgttgag ttatgctggt attgcggcta tatcgcatga ttttcatact
     2821 tatcacctat tgcctttact gccttatgct ttgattttgc tatcaagctc tgttggccga
     2881 caatatgagg caggacttag gacggttagt catcgtcgtc gtaaggggaa aaatggtgcg
     2941 agacgggtta ttgctattta tctaaataag catttctatg tgccagcaat cataatgcta
     3001 ggagcggttt ttggcacagc ttatcagtat gtgaccagct ctgccattaa tcaagagcgt
     3061 tctcagattg ctcactatct aagacagagg ctagcggagg accaacccat ctatgtatgg
     3121 gacgatacgt caaaaattta cctggagacg caggccaaat cagcttcaca gtttgcctcc
     3181 ccctttgtta atctgaaaaa ggagagtcat caacagatgt tagaggatga gctactacag
     3241 aataaggcag cctatattgt ggtcaataag caaaaagcat taccaaaggc agtcaagaaa
     3301 atagtgacag ctaattataa aattgacaga aagattgatg ttaagggctt tagcctatat
     3361 cagaaaaaat aaataaaatc aatatattgt gtcggcacaa aaaacttaac acaatatatt
     3421 gatttttttg tgtggcgtga tataatagtc gagtaaggag ataggacatg ataacattag
     3481 aaaaagacaa agttattgtt cagccagcta ttaaggttat taaaagagat ggacgcttag
     3541 ttaattttga tgcaacaaag atctacagtg cgctgttaaa agcaagcatg aaggtaacac
     3601 gcatgtcacc gctcgttgaa gcaaagctag aagctatttc tgaacgcgtt attgcagaaa
     3661 ttatcgagcg atttcctaca aatattaaaa tttatgaaat tcaaaatatt gttgagcatg
     3721 agctattagc cgctaatgaa tatgctattg ctaaggaata catcaattat agaacccagc
     3781 gtgactttgc tcgctcgcag gcgacagaca ttaatttttc tattgataag ctcattcata
     3841 aggatcagac agtggtcaat gagaatgcca ataaggatag tgatgttttc aatactcagc
     3901 gtgatttgac agctgggatt gttggtaagt ctattggctt gaagatgctg ccgccacatg
     3961 tcgctaatgc tcaccaaaaa ggtgatattc actaccatga tttagattat agtccttata
     4021 cgccaatgac aaactgttgt ttgattgatt ttaagggaat gctggcaaat ggctttaaaa
     4081 ttgggaatgc tgaggttgaa agtcctaagt ctattcaaac agcaacagct caaatttcac
     4141 aaatcattgc taatgtagcc tccagtcaat acggtggctg tacagcagat cgtattgatg
     4201 agtttttggc accatatgct gagttaaatt tcaaaaagca cctggctgac gctgaaaaat
     4261 gggttattga ggagctacgt gagagttacg cctttgaaaa aaccaaaaaa gatatctatg
     4321 atgccatgca gtccctagaa tatgagatca acacgctatt tacctccaat ggtcagactc
     4381 cctttacctc attgggattt ggtctaggga cctcttggtt tgagcgtgag atccaaaagg
     4441 ctattctaac aattagaatt aatggtttag gcagcgagca ccgcaccgca atcttcccta
     4501 agctcatctt tacggtcaag cgtgggctca atttagagcc agactcacct aactatgata
     4561 ttaagacctt agccttggaa tgtgccacaa agcgcatgta tccagatatg ctgtcctatg
     4621 ataagattat tgaactgaca ggatccttta agtcaccaat gggctgtcgc tctttccttc
     4681 aaggctggaa agatgagcag gggcaagata ttacctcagg acgcatgaac cttggggttg
     4741 taaccatgaa tttacctcgt attgctatgg aatcaaatgg cgatatggat aaattctggg
     4801 agctgtttaa cgaacgatta cacatttgta aggacgctct tgtttatcgt gtagagcgcg
     4861 ttaaggaggc aacgccagcc aatgctccta ttctttacca atatggagcc tttggcaagc
     4921 ggctagctaa gactggcaat gttgatgagc tctttaacaa tcgccgcgca actgtatcat
     4981 tgggttacat tggcttatat gaggtagcaa ccgtatttta cggtgggcaa tgggagcaca
     5041 accaagaggc caaggacttt acaatcacta ttgttaagga aatgaaaaag gcttgcgaga
     5101 cttggtcaga tgaatatggc tatcatttct ctgtttactc aacaccatca gaaagcttga
     5161 cagatcgttt ttgccgccta gatactgaca aatttggcgt tgttgctgat attacagata
     5221 aagaatacta tactaattca ttccactatg atgttcgtaa aaatccaaca ccttttgaga
     5281 agctagattt tgaaaaggat tatccagcag ccggtgcttc aggtggcttt atccattact
     5341 gtgagtaccc tgttttgcag caaaatccca aggccttgga agctgtttgg gactatgctt
     5401 atgatcgtgt gggctaccta ggcacaaata cgccaattga taagtgctat gaatgccatt
     5461 ttgagggaga tttcacccca acagagcgag gctttacttg tccaaattgt ggaaacaatg
     5521 accctaagac agtagatgtg gttaaaagaa cctgtggtta tttaggaaac cctcaggctc
     5581 gtccaatggt caatggtcgt cataaggaaa tctctgctcg tgtcaagcac atgaacggat
     5641 caaccatcaa gtatccgggg atataagcct tggagaataa tctcattaca tctatatcat
     5701 tgtaaaggat tgcttcatgc aagcagtcct ttagttatca agacaggtct gtaacaaaga
     5761 gagggagaaa catgggaaaa taccagttag attataaggg aatgcagcaa gtagagaggt
     5821 ttcatgagaa acattctgtt gcaaaaacag acaaaaagtc tcgagtacag cagcttagag
     5881 cacaattttt agaaaaagca aagcaatcaa agaaataatg gcacactcag taaaggcggt
     5941 gaagaatgct agatattgga attgttgggt taggcgctat ttcacaaaag gcctatttac
     6001 cctatatgcg tcaattaaga ggaatcaatt ggcatttatc tactagaaat gcgttagtcc
     6061 gccaggaggt gggtcagctt tttggttgcg caaggcttta cagtactgtc aatgagttac
     6121 ttgaggctaa gttagatggt gtgtttatcc atgcagccac taaggctcat ttagagctgg
     6181 ccagtttgtt tttacaaaaa ggaattccag tttacatgga taagcctctg acggaggatt
     6241 tctttagcac gcaggctctt tatcaattag cagataagca caataccttt ttgatggcag
     6301 gctttaatag acgctttgca cctggtgtca agaagttgtc aaccctgtca accaagcgta
     6361 aagttgttgt tgagaaaaat gatattaata gaccaggtga caaacagttt aagctttttg
     6421 acttctttat acacccttta gatacagctt tatttttagc tgatgggagg cttgttgcag
     6481 gctattttca ttatcagctg actgataatg atttgctaag tcaggttagt gtaaccttaa
     6541 ggacagaaca gactattatt tcagcagcta tgaatctaca gtcaggtagc aggcgtgagg
     6601 tgatggaggt tcagacacct aaagagacct atcacctaga aaatctagag accttgcgag
     6661 cttatcgagg ggttgatcaa gagatcaagg gatttagtgc ttgggatact accttatcta
     6721 aacgaggctt tgaggctatt gtggattctt ttttacaggc tgtcaaggat ggtgttaacc
     6781 ctgtcaagcc agagacaagt ctgttgagtc actggatttg tcaccaaatt tgtcaatctc
     6841 atgaagctga tggcatatta gatgtttctc ttcccttata aaggagtgat aatatgaagc
     6901 tacgaagacc taaaaagcaa gatgaagcgt ctgttttaga aatgatggca gagtttgaag
     6961 actatcagtc tcctcatgat ggtggttttt ggaacgctga gcattttgat tatgaaaaat
     7021 ggttggaatc taatgctctg atggaggctg gcttagctat ccctgagaat tgggtgcctg
     7081 ccatacagct cgttgccttt gctgatcaac aggctattgg atttgtcaat gtacgcttga
     7141 gattaaacga agagctactg gtcaaagggg ggcatattgg ttattctgtt agacctagcc
     7201 agcgtggaaa gggctatgca aagctgatgc taaaggaagc cttgcagctt gctcgtcaaa
     7261 agggcattcg tgagatttta gtgacttgtc attgcagcaa tagtgctagt cggtctgtta
     7321 ttttagctaa tggtggtcag ctgaaggatt gcaataaggg tattgaacgc tattggataa
     7381 aagcataaga ggcaataatg aaggaaaact gttggaattc tcccaaacca aaagaatgga
     7441 catcagaggc attaagccaa ggacgcgtta ttgattataa ggcatttaat tttgtagatg
     7501 gggagggagt gcgaaactca ctttatgttt caggctgcat gttccattgt aagggctgct
     7561 ataacgcagc aacctggtct tttaaggcgg gtattcctta tacgaaagag cttgaggagc
     7621 aaattatgac tgatcttgca aagccctatg ttcaaggttt gacacttttg ggcggtgagc
     7681 cctttttgaa tacgggaata ttgattcctt tgattaagcg tatcagaaaa gagctgccag
     7741 aaaaggatat ttggtcttgg acaggctata cctgggagga aatgatggaa gaaacccagg
     7801 ataagctaga gctgttaagc atgattgata ttttagttga tggccgcttt gatatcacca
     7861 aaaagaatct gatgctgcaa tttcgtggat ccagtaatca gcgtatcatc gatgttaaaa
     7921 agtcactggc tgctggagag gtggttattt gggataagct aaatgatggt gatcagtcct
     7981 ttgagcaaat gagccgcgat gatttgattt agtagagact tatcaacatc actagacttg
     8041 aaagctaata atgaaagcat gattttaggc tcctgtggtc ttgcttaacc aatctaataa
     8101 ggggttttcc ccacattatc ctcatactta tccacaggtt gtgaataacc tgttgatttg
     8161 tggataaaaa aagagaatta aggggttctt taattctcta ggcctgaaaa agggttcttt
     8221 ttgatgtttt tttcttaaaa gaaagagagg ataatgacct ctcttgaaat aatataatta
     8281 ggttttaagc ctaggtttca atatttctga atacttgatt tccttgggag tcaggcattt
     8341 tttaatggcg atgggaagta cgacttgcag cttgccttgt gtgttaagag actttctgag
     8401 ctgctatcct taaggattag tgatgtaaca gctgaggttt gttcacattc tgagagcatc
     8461 aagttttttt ctagctttct tttttgatat agtaataatc agtttctgtt gatagctctt
     8521 cattgtagca aaagccagca aagctcagtt gcttaagtgc ttccttggtt tggacattgt
     8581 tttctaggca ggctgttaga aaggctcctc tagctttttt tgaaatggtt gaatgcgtct
     8641 taagctgccc tgatctttcc tccataaatt tgggacttat ccacagcttt tgatattcct
     8701 ttgaaaaaac gtccttaaac tcgctagata acaaagaaat gatttgcttg tgatctttag
     8761 caaactgatc gtagataggg cgccaataat gcttaaggct ttgcccattg atggttactt
     8821 tagtgtgaaa atcatgccga tgctctgcga ttttctcatc agtagggata atgccataaa
     8881 aagacgaggt aatgtagacc tgctttgaga ggtagtcttg ctggtcttta gagagattgt
     8941 cgcgcttgaa atgacggtac atgagcccat taaagagctg ataagcagga taagcagaac
     9001 tctgcccttg agctatggcc tttagtctct tggcttcctt gcttgctgct tctatactga
     9061 tgctgtaggc ccttgctagc tcctctaggg atagttcagc catagcctct aatatgggca
     9121 ggcttttttg gggaagctga tgtggatagc aaggtggaac tggtttcatt tctttagctg
     9181 ttggaattaa aaaagttaac ataagtttag tgtagtaaag gcggcaacct tctgtcaaga
     9241 gtgggataca tttggtggtt atgtcatatg aaactaattt ttatattttt tacattttga
     9301 ttagttttta aaaatatagt gatttagtgt tgcataacct ctctaagtat gttattatat
     9361 actcaagtct gtttgataaa cagaagctca ggtcaagtaa gtgttccact tacaataacg
     9421 cagttgatga tggggagact cagagtcaag gaaaagaaat atagtcttgt aggattacct
     9481 acagggcttt tttctatttt gaattgagag atcaatataa ggtgatgtgc tgttttttat
     9541 taccttaaac atttggatat tggctattga caaaaagtgt aaaggaaact atactatatg
     9601 tgtaaagtta acttgacata ttggaggaac catggaaaat cggatacaag aactccgtaa
     9661 gtcacgaggg attagtcaag ctgatttggc agatatgatg tgtgtcacta ggcaaaccat
     9721 tatctcctta gagaaaggac gctataatgc gtcattagag ctggcctata aattagcgac
     9781 atttttcaat ctgactatag aagacgtttt cttgtttgaa gagaagggag aatgagatga
     9841 tatttagtga tttaagcgtc ctgctgactc aaaaaagcca gctagcctat gccaaaaggc
     9901 tgaagtatat gggctttttc gctctctgtt taggcggttt gtttttgttg ctggcctttg
     9961 acgtgagact gacgagcttt gctcagggaa tgctggtagg gcttggtagt ggtagcttat
    10021 tattaggtgt tcgtgctttt cagattgcct ttaatcctca aaggctgaga gcctcttata
    10081 ttaaggctta tgatgagcgt catcaggtag ttatcaagct agctgctgta tcaaccttaa
    10141 tcttattagt ggtgttgatt attggcggtc tgtgcttgaa tgttttttgg ggcttagttc
    10201 ttggctttag agtattttta gagatttgtc tgtatacgat cttgcttggt tttttaggca
    10261 tcaagctatt attagagcat gtgatttagg aggcttcaat ggaaacaaaa cattcagtgg
    10321 taaaggtcat catcagtaaa ttaaaatggt ttggcttagc tcttcttgtg tttatgcttg
    10381 agcaggctcc aacatttttg ataacaaaag aacagccaat gtggcagaca cttcttcttg
    10441 tggtcatttt tcttttgatt agtggaggta cttattacct agctgtgaag cttcacattg
    10501 tgggagatca agctattcct aagaatgact atcgggcact ttggattggt ttgggagtgg
    10561 tagctgtctt tgttgtcaag atgattggtg gtattttgtt gtttttggag catggtccgg
    10621 gagccaatac ggtcaatcaa gctgccttag aacaggcagg cttatctccg attcttatgg
    10681 ttacgctagt tgctattgtg gcaccaattg tggaagaaat tgcttttcga gggctgcttt
    10741 atgggaagct ctttggtgca gagtcttatc tgggcttgat ttttagcagt atcatgtttg
    10801 gcttgattca tgtgccaaca gattttggca gttggtttat ctatggcggt atggggctgg
    10861 tgttaggctt tgttttccat aaaacaaaga aggtcgaata cacgatattg attcattttt
    10921 tgaataatgc actagctgtt cttatcatgc ttttgctgcc ttatcttcag tagtactgct
    10981 tgagtaatga agggggtaat gaatgaaaaa tgatcattgg attgacaaaa aatatcaacg
    11041 ttgggagaaa gtgtataaga gacttggtca ttctttactg acaatcggtg tgttggtagg
    11101 gacttatggg atttttttga ttattcaagg gaatcatcaa acgggctttc tcctttttat
    11161 cctggggcct atactattga ttgcgtcatg tctttgctat tatgtgttta cagagccaac
    11221 gtctttacga gaatatctga ttaatagcta tgatgagcgt aaccgagcta ttcgtcagaa
    11281 aacacaggcc tactgctttt gtctatttgc ttttctcttt ttgatgcttg cgatattctt
    11341 tccaaatatg acgatcaagg agctttttgg gtataatctt ccgttgattg ttttcaatct
    11401 gtatatcatg attagagcct gggttagtaa acacatgtag gtcatgttaa cacaaaggag
    11461 tctagagcaa gggctttgaa tgaaactatt tttctaaaaa cgcaaaaaat cgcgtgcagt
    11521 aacagattag gccatgttac tgcatgcgat tttgttgttt caaacgtgag ctcagaatga
    11581 catatccttt ttagaaagaa taggtattta gggctgtctt gagctagtct taggtaatga
    11641 gcttggagct cattggtgat ggttaggata ggtctttagc ttttttgatc gttgtgtcaa
    11701 tggcagagca gacagaatgt gtcaggcctg ttttttcaag atccatcaag cctgcaatgg
    11761 ttgtgccgcc gggactgcag atcttatcaa tcaaatcatg gggactatct gtgctgacta
    11821 gcaggttctt ggcgctagct aggacagttt gactaacgat actaagggcc ttgtctttag
    11881 gcagtccatt tttgactccg gcctttgcca tggcttcgat gaaaaggtaa aggtaagcag
    11941 gacttgaccc tgctagggct gtaaaggcat caaaatcctt ttcagctatt tcaaaggttg
    12001 ttccaaagct gttggttagc tctttagcag tagctaataa atcagcagtt actaagtcat
    12061 taccagtcaa agcagtggtg ctttggagaa tttgagcatt catatttggc atgatacgta
    12121 ggagcgggag atcagtgctt gttagttgag ctagtctgtc taaggaaata ccagcagcca
    12181 ttgacatgat aggctgcttg aactgtagag aactaagaac ggcctcaaag agctgtggct
    12241 tgatccctag aataatgaag tcaacctgat caatcagctc ctgatgagat tgagtgtagg
    12301 ctaattgtag ctgatcagca atttctttag agcgttgaac agaggagcct gagatgatta
    12361 gctcgtgtgg tgtgtgtgtt aggccttgaa tgatagcagt tgccattttg ccaacaccga
    12421 taaatccaat tttcataata atgttcctaa aaatgaataa aggctcaata ggctagagtg
    12481 ctcattgaac cttagattcg cattttagcc ttatccttcc tagtatttct tgattaaatc
    12541 aactgttgag cggtcaagcc ttttgacaat ggcttgtaaa aaggcctgtg cttctacgaa
    12601 atcatctaag gcgtacaagc tctgatgtga gtgaatgtag cgagcgcaga caccgattgt
    12661 agttgaaggg ataccgccat ttttgaggtg ggcagcacca gcgtctgtac cgcctttacc
    12721 acaataatat tggaaggcaa ccccagcctc ctcagcggtg gttaatagga agtctcgcat
    12781 gttcttaagc atgatgtgtc cgggatcgta aaagcgtaga agggttccat caccaatatg
    12841 gccaggattg ccataaatat caccagcagg tgagcaatca acagcaaaga aaagctcagg
    12901 atcaaatgta gtggctgaaa catgggcacc acgaagcccg acttcttctt ggacatttgc
    12961 tccagcaata agagtgttgt gaagtgtctg gtcttttaag gcttctagca gctcagtgac
    13021 catgagaaca ccatagcggt tgtcccaggc ctttgagatg atattctttt tattggcagt
    13081 taaaatggtt tcagactgcg gtacaataat atctcctggt gtgatgccaa agctttcggc
    13141 ttcagccttg tctgtaaagc caccatcaaa aacaatatct gaaaccgctg gcagattagc
    13201 agcaccattt gccccgcgca gaaaatgggg aggaactgag cctgaaataa caggaatggc
    13261 ttggccagcg cgagtgtata aggtaaagcg ctgtgagcta acaactagcg gattccagcc
    13321 gccaatttca acaacccgca gtgttccatc agctttaatc tcgctcacca taaagccaac
    13381 ctcgtccatg tgagccgcaa caagaattcg aggagcttga tctgccttgc tttcttttat
    13441 cccaaatatg ccgccaagtc catcaacctc cactcggtca acaagcggtg tgatcttagc
    13501 gcgcaagtaa tcccgaatag tgtgctcgta gccggcgatg ccgtctaatt cagtaacttc
    13561 tttaattttt gaaaataaat caatcatttg tatactccat ttgtcataat aagattaaag
    13621 gtattatgtc tgcctctatt ctatcatttt ttggttaaga atgggaaata gcctgagcat
    13681 aggaaaagag cttgggagat taggtgtgtt tttcttgctt gataggctgc ttatcagttt
    13741 gattcagatg agatggctgt tggtattaag gaaatgggac agctgtcttg acaaggattg
    13801 acagacctga gctgtctgat gccatcaatc gtacttaaat agagcagtag cctgatgttg
    13861 gtgtgattag ttgctcttgt caggtggttt atgattattt cccaagtgtc agttagcctt
    13921 ggctgagatt gttagttttt gctctagcct attattccct ttttgtgata aaataaaagg
    13981 tatgagtgga aaaaagacac gtattgtttc aggattaatt gggctgggct tgctagccgg
    14041 cttgggattg aggcttaagg aagtctatca agaaagagag cgtcagaagg tattggctga
    14101 gttgcgcgcc tttttctcag ccttaggaga gattgaggtc ttgtacatca actcctttag
    14161 ctcaaagcgt gatgatgtca ctggtggcct tgtcatgaca gatggtaaaa cctatactta
    14221 tcgttaccac aagggaagca ttgattttaa agaggatttg acatgattat tccaaagtct
    14281 aaggacgagc ttgctagact aattgagaca gagcctaggc tggtcttgtt ttttacagca
    14341 gattggtgcc cggattgcca gtatatttat cctgtgatac ctgagctaga ggctgaaaac
    14401 ccggatatga cctttgtccg ccttgatcgc gatgatttta tcgatttagc gcaggattgg
    14461 caaatttttg gcattccaag ctttcttgtt atggaaaagg ggcaggagaa gggccgtttg
    14521 gtcaatagat tacgaaaaac aaaggctgag attagtgact ttctagcagc ctatcactaa
    14581 gaggagaaaa tgagatgatt tttgcatata ataaagagca ggtcggtgat gttttgatgg
    14641 tgatactaga ggataaaaaa gacatcaagc gacaggttga gcgtaagggg agagtagtgc
    14701 gtgtttttgc agaagagaca gggcaaaccc ttgcttggaa tatttttgag gcgtcagcct
    14761 taatcgctgt tgagggaaat gggcaggttt tcttgtctga ggaggagtta gcgattttaa
    14821 atgcggagct tgctcaagaa ggatttactg agcgactgga ggctagccca gaccctgttt
    14881 ttgttgtggg gcaaatcatt gagatgattc ctcacccaga tagtgatcat ttaaatatct
    14941 gtcaggtaca gattgctcct gatagggctg tgcaaatcgt tgcaggagca cctaatgctg
    15001 ctgttggctt aaaaacaatt gtggccttgc caggtgctat gatgccaagt ggcagcctta
    15061 tttttccagg aaagcttcgt gggaaggata gctttggtat gatgtgttct ccacgcgaat
    15121 tggccttgcc aaatgctcca caaaagcgtg gtattattga gcttggtgat gctgcagtgg
    15181 tcggtgaagc ctttgatcct gctaagcact ggcagagcta gcaggacttg atcagcatta
    15241 aaatggtgtt tagtccttct tttgcttggt gaaaagcctt tggaccttga gccatgcagt
    15301 gctttttgct ggtctgtgac tgtctttagc ttcaggctcg aagcattaga gtagctgctt
    15361 aacttattgt cagcgctgtt gattgcagta gcgctatgct tgtgacaagt gaaggcaaag
    15421 cctatcaatg cccttggcta gggctaaaaa ttgtctttag agtcactttt gaggtgagta
    15481 gctcgctaat ttcggtattg aacggtgctt aggtaccgtt tttttaagct ttgctgagtg
    15541 tgacatgctg aaaaaaggcc atgtctttat atggcttttg gtcacagatg gctaattcaa
    15601 tcatccgtaa cgcttccagc caatcaggct tagctttaac ctcatttggt tgaagtccgt
    15661 agcatgtccg cagtccacga tagctttgga gcttcaaatc ggtctttctg agtaagtcat
    15721 caatactgta ggtctgacct gctgcaaagg ataagcttca cagcttgtcc ttattttacc
    15781 atgttttacg aataataaga taaggaggta cgacatgtac aataaagtaa tcttgatagg
    15841 ccgtttagtg gccaagccag aattaaccaa gacattaacg gataagcagg tcgttcgatt
    15901 taccttagca gttaatcgtc ggtttaagac gacgactggt gagcgtgagg ttgattttat
    15961 caatgctgtt gcttggggag gcttggctga aaccttggct tcctatgcta gtaagggaag
    16021 cctgctgtca cttgatggcg agcttcgcac acgaaaatat gacaaggctg gtcagactca
    16081 ttttgtgaca gaggtcttgt gtcactcttt tcaattgctg gaaagtcgag cgcaacgggc
    16141 catacgtgaa aacaacgctg ctaatgattt gattgatttg gctttagagg aggaaaagct
    16201 tcccttttaa aatcagctgc tagcttgccg tcgctaagga aggaagtcag acactggagc
    16261 attgcgcatg ctagagatct caacataatc taaaaaatga caatgatcct aaaaaaaatc
    16321 ttgacacgtc ttagaaaaag gtttacaatg tatgacaatt aaaatgaaag aaaacaggag
    16381 gtgctggtat ggtagcagtt agcacagctc agacgatgac taagcgttat tactttagct
    16441 tctttagata gtgtttgtag acatgagcgc atggatacaa acacactgaa cgttatgttt
    16501 gtatctatgg ggctaagggc tatttgagtt gtttgtccac atagatgata tctcttctaa
    16561 gtggacacca tacagcatgt attttgttat ctcatgatac ctgtataaga ccatttagat
    16621 tatctagatg gtcttatttt tatgcaagaa agaggaaatg acatgagatt taaacagtta
    16681 tccttaacag cctttatagg gcttttagca atgctgctaa cggcttgtcg acaagaaacc
    16741 aaccaaacgc ataaagctgc tagggttgga attattcagt atgctgagca ctcagcctta
    16801 gatgctgcgc gcgaggggtt tattgaggcg cttgagcagg gcggcttcaa agaagggaag
    16861 aacctgacca ttacaacaaa aaatgcacat ggcgatcagg ctaacctgca aacaatggtg
    16921 gagcagctgg cgggtaagaa cgacttgcag cttgcgattg caacgccagc agcgcaggct
    16981 cttctaaatg tagactcatt gaccccggct gtatttacgg cagtaacgga tcctgtctca
    17041 gcaggtctgg tcgatacatt agctaagcct ggtggaaata tgacaggctc tatagatgcg
    17101 actaatgttg agaatcagat tgatctgctg actaaggcat tccctcaagc taggacagtt
    17161 gggattttct acaattcaag cgaggtgaat tcggaggtac aggctaagaa ggccaagagg
    17221 gagcttgaga aaaaaggctt aaaggtcctt atgaaaaccg taaccactac taatgatgtg
    17281 cagcaggtta tgacaagctt agttagtcag gttgatgctg tttacctgcc aacagataat
    17341 acggttgcct caacagctgc tactattggg gatattttaa aggaggccaa aattccttca
    17401 atgggaagcg atgctgctta cctgagtgct gttttgttca cctcaggtgt tgattaccat
    17461 gctattggca tgcaggctgg tcagcaggcg gtagatattt taaagggtaa aaaaccagca
    17521 agcattcagg tcgctaagcc tcaaaaggca agcattgctg ttaatgatga tatggcaaga
    17581 cttctgggca ttgaccccga ggtgatcaag gctcttgcaa gtaacggagc caactagcgt
    17641 tttaggagga aggtatgaaa aaaggaagct atttaatact gttagtgctt gcaggcttcg
    17701 ttttggtggc ttgtcgttcg acagctagtc ctcgtaaggt taaccaatct catgttaaca
    17761 tcggtatttt acaatacatg gagcatgatt cgctgacggc agctcgtcga ggctttgaag
    17821 cgcaattaaa ggcagcgggc tatactaagg gagacaagct gagccttcat tatcaaaatg
    17881 cacatggcga ccaagctaat ttacagacga tttcagagca gctagtgaag caaaatgatt
    17941 tgatcttggc tattgcgaca ccagcagcgc aagccttagc gactgtctca tcagatagac
    18001 caattgtttt tacggcagta acagatccta tctcagcggg cttagtggat aggatcaaaa
    18061 agcccggtgg cttgataaca ggaacaagtg accaggcgcc gattgcaaag caaatcgact
    18121 tgttagccca agccttgcca gaggccaaaa ctattggcat tttatacaca gctagtgaac
    18181 gcaatgctga ggtgcaggta aaggaagctg aaacgctact gaacaaggct ggctataagg
    18241 ttatcaaaaa gggaattgcc acttcaaatg atgtgcaaga tactgctgca agcttgatga
    18301 gagcagtaga cgcatttttt gtaccgacag ataataccgt tgcttcgacc atgacaatgc
    18361 tgggtgagct gtcattggct aataaggttc caatcattgg tggctcaacg gatatggtcg
    18421 atgcgggtgg gctcttgacc tatggtattg actatgagag ccttggtaga caggctgggg
    18481 aaatggccat taagatttta agaggacaag atccggcaag cctagcagtg gagtacccaa
    18541 aaaccgttaa gctacatatc aatcaagcaa tggctgacaa gctagcgatt gatacttcca
    18601 cattatcagt tgactaaatc gctaggctaa aggctaaatg actgatctct agccagctgg
    18661 ctaaatgaca aagtcttaac cagttagctt agcttactat taacgattca tatgacaaaa
    18721 aaggagaaat catgtcactc attttatcga gcttatcaca gggcttattg tggtctatta
    18781 tggcaattgg tgtttacctg acatttcgta ttttagatat tgctgatttg actgcagaag
    18841 gctcctatcc gcttggggca gctatttgtg caacgggtat tgtatcaggt gtctctccct
    18901 tgctggctac gtttttagct tttgttggag gcttgctggc aggactcgtc tcaggattgg
    18961 ttcacaccaa attaaaaata ccagccttac taacaggaat tatcactctg acaggcttgt
    19021 attctgtaaa cctaaaggtg ctaggaagag ccaatgtggc tttattacgt caaagaacct
    19081 tagttaccca gctctatgat ctaggcttta ccaagcttgc agcggtgcta attatgggct
    19141 ttgtctttgt gaccattgtg attcttttat tagccttgct gatgaaaact cagcttggcc
    19201 tagctctgcg ctcaactgga gacaatggtc caatgagtga agccaatggt atcaaaacag
    19261 atcagatgaa gattatgggg tatatgctat ctaatggttt gattgcccta tgcggtgcct
    19321 tgctttgtca gaataatggc tatgcggatt taaatgctgg tgttgggaca attgttattg
    19381 ggctggcttc gattatcatt gctgaagtga tgatcaggca gctaagcatt ggctggcgct
    19441 tagcttccat tgttttaggc tctattgttt atcgcttaat tattctagct atcttagcca
    19501 ttcccggtat ggatgcagat ttggttaagc tcttttcagc catgctattg gcagcggttc
    19561 tttttgtacc agaattacag caaaggcttc gccttagaaa aacaagctta ggataggaga
    19621 catcatgtca gcgatattat caattaaggc tattcacaaa acgtttgaag caggtacgat
    19681 taacgaaaat catgtcttga gaggcttgtc tttagacgtt gaggaggggg attttatctc
    19741 ggttatcggt gggaatggcg ctggaaaatc cacattaatg aataccctag cgggaacctt
    19801 gtctctggat cagggtgata ttcttttaga gggaaaatca atccagcatt tatcagcagc
    19861 taagcgtgcc aaggacatca gtcgagtgtt tcaagaccct aagatgggaa ccgcttcacg
    19921 cttgaccatt gaggaaaata tggctattgc ttaccgtcga gggaaatcaa ggggtctagg
    19981 ctggggcgtt aaagaaagag agcgccagat ctatcgtcag gccttgcagg aattaggcct
    20041 aaatctggaa aaccgtctta aggccgaaac acagttttta tcaggagggc aaagacaggc
    20101 cttgaccctg ttaatggctg ctttagagaa gcctaaggtt ttgctgctag atgagcatac
    20161 cgcagctctt gatcctaaga ccagtgcaat ggtgatgact ttgacaaggc agcttgtcga
    20221 gacacatggc ttgacaaccc tgatgatcac ccataatctg gaaaatgcta ttgcttatgg
    20281 taatcgtctg gtcatgctcc atcaaggcaa tattgtggtg gatattaagg gagaggagaa
    20341 ggccaatctg actgtcgatc acttaatgac actctttcac caaaatagtg gtcacatgct
    20401 ccttgatgat gcacttgttt tgggataggc aagatgaagt ttagctctgt tttcaaatag
    20461 cagccataat aaaaaggctt aaagctaacg tttttagaaa cgctagctca agccttgtta
    20521 tagtacttaa gatatttttc taagagtgaa aaaaccatgg tggcggccat tgtagtcaaa
    20581 ggatttgttt cggacgcgat aggcctcatt ttccacaatt gcaattgctt tattgagctg
    20641 ctgaacggtg atcgcttcgt caatctcatg aaaagcaatg ctataataat catcacccac
    20701 gtgttgattg cgccccctat aggtatttct atgttcagtt aaaatggcct tagcttcctc
    20761 tcgctttgca atggtattta tgatgccttg accatacgcc ttagcctcct gaaggattga
    20821 cagcatattg tctaaggaat aagcattcgc caagcggtta acaaagctat cagcagtatc
    20881 agggcttaga ttaatgccat ctaggcgata aatcatctct gggtgcagct tcagataatg
    20941 ctgcaattcg cgaaataaga gagctggaat ttttgaccta tctctaaatg gactgagctt
    21001 gatctcctga ctatgaagcc tattgagaaa atcgtccttg aaatgcttaa tagcatcgta
    21061 gtctgatttt tctagctctg ctttaatatt ggctagaatc tgggcgtctg aataacgacg
    21121 atagcttgag taaggagtag tagttctata agtattagca gtgtgagaag cttgtgagct
    21181 tctagtttga tagcttggtg ctggcggagt acttgactga gtctcctgtc cggttgatcg
    21241 taggtcagga tataagcgac taatattgtt gagaaattgg ttaacctcat attctgatga
    21301 aaactttagc ctaggtctgg ccttgacctt ctcaatagcc ttgtcaataa tccttttccc
    21361 gtaccttttg aggttactgt cagactggat caaataaaga ttaacacgta agtgatcttg
    21421 actatctgcc ttggataaga tatttccaag gctaaggctt cccaagcatg tggctagtag
    21481 aagtaagtgc tttagtaggc tacgccaaat aatgttgtta cgacgaaaca tgatattctt
    21541 cctaattcta ttatgatgtg ttcataaatg ctatcaaaat gaggataggc tgtcaatatc
    21601 attaatgagt gatcatctta aagaaatgac tcttagcctt acacatcaga aagctagctt
    21661 aacgcagacc gatagcggtc ctaagtcctc agctgatttg gtctataggt tagatttgaa
    21721 gttacttgct aagcgtgaca tatcataaaa gacctttata gctttataca agctgtaaag
    21781 gtcttttatg tatcaagtag gcagatgaat tccttgtttt tacagtaaat ctaaggtttt
    21841 tagcttttca tcaatcattt gcaggacggt tgccagatcc tctgggtttt gcacaaaatc
    21901 aagcttgttt ccatcaatcc tcatcttagg tgagacgtca taacgctcgt accaggttgg
    21961 gtattcgcca tgcacctgat agtaataggc ctctaggtca ggattgtcat caacctgctc
    22021 gaaccgcctg ccacgctttt caatgcgctc tagcatcttc tcaaaggata catcaatata
    22081 aatcagcagg tcaggacgtt ttttaggcat tccctcaagc tcctctagca tattggctaa
    22141 gagctcttgg taaatttcaa gctctgtctt ggtaacattt ccatttttat agttaagtgt
    22201 caagaagagc tcatcttcaa agattgagcg gtcaagaata ttattgtctg cctgataggc
    22261 ttctttaata gatttgaagc gcttattcaa aaagaaaatt tgcaataaaa aggcatattt
    22321 tttagggtct tggtaataca gatcaagaac aggattgtta tcaacagcct cgtaaaatac
    22381 ctctgttcct aaatgctcac ccagtgcagc agcaagggaa ctcttgcctg cgccgattgt
    22441 tccagctaat acaatcaaca tgtttctcct tctatgtagt cttagtgtat ttgtgcaaaa
    22501 atcgtttcaa cctcagctaa ggtattagcg cgtgaaacag cactccgaat tttggcagca
    22561 cctgctgtcc ctcgcaggta atgaggagct agcccacgaa attcacgaac agcaatagtc
    22621 tcccccttga gcctgatgag gcgcttgagg tgctctcttg caatgtctag ctttttagta
    22681 aagggcagct ctggcaaaac ctctcctgtc tcaaagaagt gattaatttg ggtgaagaga
    22741 taagggttgt tcatagctgc gcggccaatc atgaccgcgt ctacaccgat cccctcaatc
    22801 ataaatgcag cgtcctgaac ggttctgaca tctccatttc caataaatgg aatcttggta
    22861 atagctcttg agacgtgtgc aagggtttca tggtcacagg tgccagtata catctgctca
    22921 cgagtacggc catgcatggc aagagctgat acaccagcag cttcagcagc caaggcattc
    22981 tcaacagcta gtgagctgtc tgcccaaccg gtacgcattt tgacagtcag tggaatgtct
    23041 aaaacagagg ttacctcctg aatgatatgg taaatcttat caggatcgcg aagccacttg
    23101 gcacctgctt catttttaac caccttgtta acaggacagc ccatattgat gtcaacaatg
    23161 tcagccttgg tatggctctg gataaaatca gccgcacgct ttagtccttc agcgtcaccg
    23221 ccaaataatt ggattgacat agggtgctca ttgtcatcaa tgtgaagcat gtgcaaggtt
    23281 ttttcgttgt tatagagaag tcctttttca gaaatcatct ccatgacaac aagacctgcc
    23341 ccaaattcct tggcaatcgt gcgaaaggcc gaattggtca caccagccat aggtgcaagc
    23401 actgtccggt gagggatttc cacagagccg atcttaaaag atgagttaag tcttatcatt
    23461 gatcagcacc tccaaatcag cttggtcaaa ttggtacttg gtgccacaaa attggcaaac
    23521 aatttcagcg ccctgatcct cgtttagcat tgccaacagg tcagctttag ggaggctcat
    23581 cagggctgac gcaaagcgct ctcttgagca gtcacactga aagctcagct gctcttcagc
    23641 taatcgcttg taaggctctt caccataaat agctgctaac agagcgtcta tatgattttt
    23701 cgacgctaga agggttgaaa tcgcaggcat ttcctgaatg cgcttctcat agcggctaat
    23761 ctcttcgtca gaagcttcag gcagcacctg cagcataaag ccaccagcaa ccttaacctt
    23821 gtcctcttga tctagaagca catttaggcc aacagcagat ggtgtctgct cagactctgt
    23881 caagtagtag gctaagtcct caccaatctc accggtaatc aagggtgttg tagaggtgta
    23941 gggattgcct gttccataat cggtaatagt cacaaaatgc ccattgccca taaaaggacc
    24001 gaccagcacc tcaccggttg ctgttttttt gatgtcaaca ccgggatttt gaatatagcc
    24061 cttgacatgc ccttttgtgt cagcaacaga aataatatgc ccaaaggagg aatcgccaat
    24121 aaccttgaca gtaaccttac tatctccttt ttggttggca gctaaaatct gattagcaat
    24181 caaagtgcgg ccaagtgcaa ccgttgagga cgataaggta tgatgccttt cctgagcagc
    24241 tcggacagtc tcagtacaat ccaaaacata agccctgaaa gcaccagaga cagaaattgt
    24301 tttaattagt ttatccataa cttctattat aacataatga gcaaggcttg tgctggttgc
    24361 tttagaggaa agctgcttga aaatagagaa acactatttg gttaataata gcagctctat
    24421 aaagccactt aaaaacagag cagtgctaac aaatggtggt attcttgtcc ttagcacgca
    24481 gtaagctaat cacctaagtc agtacaatca aacaagcatc aaaaaacagc tccgataggt
    24541 tgattaaagg aagaaatgat aaaagagcta tttcgtaatg ctttgctgat aatgagcaag
    24601 gtaatcatgt ggtgtcgtat cagtgtactt tttgaaggtt ttcaaaaaat gggtggtatc
    24661 gtagaaataa aggagcttag ccacttctcc agctggtact cctcttcgta aaagtagctt
    24721 ggcttcttgt actttttcct tcaaaatata ggtttgcaac gaaatagaag aatacatttt
    24781 aaaaacagct cgtaaatgtg actctgagat ataaagatgc ttagcaatat ctgatacctt
    24841 taattttgaa taaaggtgct tatcgacgta atataaaata ctattataaa tttgctgctt
    24901 atcagaaaca cttttgttga tcaaagattc tgaaaggcta ataatagcag ctgctcttat
    24961 ttgaagcacc ttaaggatat ctggtgcttt ttctgttaga ttcataaagt gtttaatacg
    25021 ctcatagttt ttagcaacat cagtattttc agtaaagctt aactcaagga gctttgtaaa
    25081 ataaaccatc gaaagatttt tttcggctct tagtgcagaa atagaagaag agataacatc
    25141 tgatgcaggg atacaattga tttctttttt taagagttcg gtattaccta gcttaaccaa
    25201 gtcaataata tgatttaaat aatttaatac cgttgggaca tgaaacgaag gagtgttttc
    25261 caattcgaga ttagctataa tatgagggtc ctcccagatt agctgggctt cctccagtaa
    25321 atcattaatg ctttgctggc agctcatttc aaagctggtg tcaaaaaagg catcaacagc
    25381 tatcaaaagg cttcgaatat gagaagcagg aaaatgagga atggtagaga tatagccaac
    25441 tagctctttt tttgacttat caggatagcg cttcaagaag ctatcggcta attcctcctt
    25501 atagctatcc tgaaagaaag aggtgtaaaa aggcccaatg aaaataaact tgtcaccaat
    25561 aggaaacatt agagaggatt cctcaagtgt tccttcataa caagtgagct cagtattact
    25621 aggaatatct aatgttttaa ttaattcata gtaggggaat cgacgctcct cgtcatcata
    25681 agcttgaagg agctcaagat tttgagaaag cactaaaaca ggtaattgtg ataggttatg
    25741 caaagcttga atgtgtttta aatgaaacga aaccattttg gtatatgacc tttctgactt
    25801 gttagctaaa tgactaagcc gtttagccaa gcatctgatt actcacaaag tagctgatta
    25861 gtatgaatgg agaagtcatc aacaagaatt attaaaaata ttatcttttt cat
//
LOCUS       DARYSY010000027        25515 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYSY010000027 DARYSY010000000
VERSION     DARYSY010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25515
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            234..515
                     /locus_tag="TVR04_001065"
     CDS             234..515
                     /locus_tag="TVR04_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1269764.1"
                     /translation="MNYLTALTILTFSSALPVLAVSHRVGEWTCGGHHDPNNWGAFSN
                     YYHGTQYHWAYVGSQGRDNQRTVYSGARSAAYAFINTNFGERVTFDAGW"
     gene            620..2635
                     /locus_tag="TVR04_001066"
     CDS             620..2635
                     /locus_tag="TVR04_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1269765.1"
                     /translation="MKKLFILLSNLLASLFFVWVFTIWSDTYVSHYYPNIAVHDSSPE
                     TTFQQVTERLEKLAKETDSFIAIQHQDPTSEGTTAFSYTTFGEGKLPDGLQERTLKDS
                     QNSSVETNYFIFDGHLDIHLLRDELSHLCLTNMHLTIPSKLSTLLSIFSFGFQLIGLL
                     IFCLTFGSLTLINQISQLRSSGIRLISGERRGSIFLRPVVEDLKGIAVGFGLAVMLTI
                     VLQKLLSLPKESLLTIGAGLLSYNLILLLISLFFAQLFAVGIKKVHLMQIIKGQVPVR
                     GIISLILIGQLLAVIIVTLGIGSSLKYSQAWLQHRLGKEAWSQERQLIILSISREGTS
                     PGFDEQTQRKLTVWYNLMDQAVSEQKAILSRHQLIDRLMQNGISSSKNLTTSTEWQDY
                     SPNGNVLIVTPQYLERQNIPVDTAIEQKLNHLAVGEFILLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQNGRQQMTATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQ
                     SVMFWFDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQSGYHNYITLLNNIQRERWIM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLG
                     FVASVFLQVEIVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2637..3269
                     /locus_tag="TVR04_001067"
                     /pseudo
     CDS             2637..3269
                     /locus_tag="TVR04_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4281..5135
                     /gene="ylqF"
                     /locus_tag="TVR04_001068"
     CDS             4281..5135
                     /gene="ylqF"
                     /locus_tag="TVR04_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1269766.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADSTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            5116..5898
                     /locus_tag="TVR04_001069"
     CDS             5116..5898
                     /locus_tag="TVR04_001069"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1269767.1"
                     /translation="MTAMTIKDLKVRLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     KGSVSKPDYLLIDAMTLEVPIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGITPIHRQSFEPIKSMTLR"
     gene            6154..6999
                     /gene="dprA"
                     /locus_tag="TVR04_001070"
     CDS             6154..6999
                     /gene="dprA"
                     /locus_tag="TVR04_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1269768.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIVKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            7100..9232
                     /gene="topA"
                     /locus_tag="TVR04_001071"
     CDS             7100..9232
                     /gene="topA"
                     /locus_tag="TVR04_001071"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1269769.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPKEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSQLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QIDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKILEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            9347..9994
                     /locus_tag="TVR04_001072"
     CDS             9347..9994
                     /locus_tag="TVR04_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1269770.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKTCLDQLNHDFSSCIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRADKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            10015..10728
                     /locus_tag="TVR04_001073"
     CDS             10015..10728
                     /locus_tag="TVR04_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1269771.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWLCFF"
     gene            11103..12437
                     /gene="trmFO"
                     /locus_tag="TVR04_001074"
     CDS             11103..12437
                     /gene="trmFO"
                     /locus_tag="TVR04_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1269772.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELEAHPLVEIIREEVTNIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(12481..13530)
                     /gene="citC"
                     /locus_tag="TVR04_001075"
     CDS             complement(12481..13530)
                     /gene="citC"
                     /locus_tag="TVR04_001075"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1269773.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYSNSLRCLAVDQAYQGQGLLNHIVSHLIEEAYSRGHYHLFIYTKISAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQVSPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFEEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            13797..14858
                     /locus_tag="TVR04_001076"
     CDS             13797..14858
                     /locus_tag="TVR04_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEL1269774.1"
                     /translation="MLSILMTLFVGTLGGLVAKRLSIPAPFMIGSMVAVAIASILTKQ
                     VEAVSSMKIFAQIISGAYIGQSVSKSDLLNLPKLAKSIISLMSLFTLNMFLLGGVFVY
                     CFDLDPVTALLSCLPGGIMDVSLMAVDMGAKADIVATLQSARLVGMLLFLPVWVTFWV
                     NRFDPKAKATKKKIVKSASSQDTRPSRKEQLWNNIQVLSIATIGGLIGLGLKIPVGAL
                     IVSLLFSTALKVLRQTSQMPSTLRYIAQVFAGSIIGTSFTQDSLLQMGRLIVPILLLL
                     SSYLIINLFFGYIMYKKGILDLQSALFASSPAGATDISLLAGELGGDMPKIAGIQISR
                     TLYTVVIMPLLVKWLISIW"
     gene            complement(14948..15832)
                     /gene="citG"
                     /locus_tag="TVR04_001077"
     CDS             complement(14948..15832)
                     /gene="citG"
                     /locus_tag="TVR04_001077"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1269775.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKTYLDIGFYHAKEDPGLIFERLRVSGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(15825..16520)
                     /locus_tag="TVR04_001078"
     CDS             complement(15825..16520)
                     /locus_tag="TVR04_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1269776.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMIRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     KFILQEMSRRQDD"
     gene            complement(16671..18074)
                     /locus_tag="TVR04_001079"
     CDS             complement(16671..18074)
                     /locus_tag="TVR04_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1269777.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLAIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            18456..18800
                     /locus_tag="TVR04_001080"
     CDS             18456..18800
                     /locus_tag="TVR04_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269778.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPETLTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            18818..19213
                     /locus_tag="TVR04_001081"
     CDS             18818..19213
                     /locus_tag="TVR04_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1269779.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGTILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            19264..20385
                     /locus_tag="TVR04_001082"
     CDS             19264..20385
                     /locus_tag="TVR04_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1269780.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            20567..20875
                     /gene="citD"
                     /locus_tag="TVR04_001083"
     CDS             20567..20875
                     /gene="citD"
                     /locus_tag="TVR04_001083"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1269781.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLANLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            20863..21750
                     /gene="citE"
                     /locus_tag="TVR04_001084"
     CDS             20863..21750
                     /gene="citE"
                     /locus_tag="TVR04_001084"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1269782.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLNAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            21752..23284
                     /gene="citF"
                     /locus_tag="TVR04_001085"
     CDS             21752..23284
                     /gene="citF"
                     /locus_tag="TVR04_001085"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1269783.1"
                     /translation="MVKNKLGRDIPQEYADQYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKDGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDCIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            23277..23837
                     /gene="citX"
                     /locus_tag="TVR04_001086"
     CDS             23277..23837
                     /gene="citX"
                     /locus_tag="TVR04_001086"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1269784.1"
                     /translation="MSKEMIFKGEAVTLADMLRAREDRSLRQGRLLTEFPNESLLCVT
                     LNIPGPIKTSPALLEVFDNVIRAILEKLAGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELEADLPIGRLMDLDVLVLTNQLPTPISRTVLGFPPRSCYLCSKEAKICSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            23868..25259
                     /locus_tag="TVR04_001087"
     CDS             23868..25259
                     /locus_tag="TVR04_001087"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1269785.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRDDL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         7504 a         4849 c         5651 g         7511 t
ORIGIN      
        1 tcatagtttt aatattagat aagacctata atcattagcc ttcgctatca agaagttcca
       61 gtgaaaggta gcgtctataa taactaaaaa tgtgagagtt taattcagaa taattaatgg
      121 actcgatatg gtgaaggtga ttgattaaaa taacattagg tatctgtttg tagaaaaaag
      181 gagaagaaca ctataattca gactaaagtt ggagttgtat ttagtgcgat tttatgaact
      241 atttaacggc tcttaccatt ttaactttct catcagctct tcctgttttg gcagtctctc
      301 accgtgttgg agaatggacc tgtggaggac atcatgatcc aaataattgg ggagcatttt
      361 cgaattatta tcatggaaca cagtatcact gggcttatgt cggaagtcag ggacgcgata
      421 atcaaagaac agtttattca ggagcacgca gtgctgcgta tgcgtttatc aatacaaatt
      481 ttggagagcg ggttacattt gatgcgggat ggtaaaaaat gttctgaagt cagcattctt
      541 tatcaatagc tttagtaagc ttgttagtct atagaggaca ggattatttc tgtcctctat
      601 tttagaatag gggtatacca tgaaaaaact atttatattg ttatccaact tgcttgctag
      661 tttgttcttt gtttgggtgt ttaccatttg gagtgatact tatgtttctc attattaccc
      721 taacattgct gtgcatgatt cttctcctga gacaaccttt cagcaagtta cagaacgctt
      781 ggaaaaacta gcaaaagaga cggacagttt tattgcgatt caacatcaag atccaacctc
      841 agaaggcact acagcttttt cttatacgac tttcggggaa ggaaagttac ctgatgggct
      901 tcaggaaaga acgcttaaag attctcaaaa tagtagtgtt gaaactaact attttatatt
      961 tgatggacac ttagatattc acttgctaag ggatgaacta agtcatcttt gcttgacaaa
     1021 catgcaccta acgattccgt ctaaactatc tactttacta tctatattta gtttcggttt
     1081 tcagttaata ggcttattga ttttctgttt aaccttcggc tctcttactt taattaacca
     1141 aatcagccaa ttacgctcgt caggtattcg tcttatttca ggagagcgac gggggtcaat
     1201 ttttcttaga ccagttgttg aggatttgaa aggaatagct gtcggtttcg gtttggctgt
     1261 catgctcact attgttttgc aaaagttact ttcgcttccg aaagaatctc tgttgaccat
     1321 aggagcaggc ttgctcagct ataacctaat actgctgttg atttccttgt tttttgctca
     1381 actcttcgca gttgggataa aaaaggtaca tctgatgcag attataaaag ggcaagtgcc
     1441 tgttagagga attattagtt tgattttaat cggtcagcta ttggctgtta ttatcgtgac
     1501 gttagggata gggagtagtt taaagtattc ccaagcctgg ctgcagcata ggctaggaaa
     1561 agaagcctgg agtcaggaaa ggcagttgat tatcttatcg atcagccgcg aagggacaag
     1621 tccaggcttt gatgagcaga ctcaaaggaa actcaccgtt tggtataatt taatggatca
     1681 ggctgtttca gaacaaaagg caatcttatc cagacaccaa ttgatagatc gtctgatgca
     1741 aaatggcata agttcctcca aaaacttgac aacttctaca gaatggcaag attacagccc
     1801 aaatggcaat gtccttattg tcacaccgca atacttggag cgtcaaaaca tccctgtaga
     1861 tacggctatt gaacaaaaac tgaatcacct cgcagtaggg gaatttatct tgctcttgcc
     1921 tgagcatctc cgttcagagg aagaacatta caaatctgtt tttgaagacg acttaaccag
     1981 tcgcatgtct agtcaaaatg gtcgacaaca aatgactgca acggtagctt atttggaatc
     2041 aggccaagac cgttttgtgt ataatacgac acctatttcc tatcaacagt ttctgaaaga
     2101 tccaattatc attgtcgtga caccccagtc aactggacct cagtccgtca tgttttggtt
     2161 tgacgcagta cagaattatg tcctctttaa tcagttgtcc gatgcccagg agcttatcca
     2221 gagacagggc attgaaaatt gggtttcaga aatgcaatcg gggtaccaca actacatcac
     2281 attgttgaat aatattcaga gggaacgttg gataatgctt gcgggagctg tgcttgggat
     2341 agcaacctca atcttgttgt ttaacaccat gaataggctc tactttgaag aatttagacg
     2401 tgccattgtc atcaaacgta ttgctggact aagattttta gaaatccatc ggaattacct
     2461 cctggctcaa ttgggtgtct ttttactcgg atttgttgcg agtgtattcc ttcaagtaga
     2521 gatagtgatt gctttcttag tattgttgct cttcactggc ctatctcttt tacaattaca
     2581 tgttcaaatg cagaaagaaa acaagatgtc catgcttgtt ttgaaaggag gttaacatga
     2641 ttgaacttaa acaagtgagt aaatcttttg gagaacgaga gctattttct aatctttcaa
     2701 tgacatttga ggttggaaaa gtctatgctt tgattggttc aagcggtagc gggaaaacaa
     2761 ccttgatgaa catgatgggg aaattagaac cttatcatgg gactattttt taccgagaca
     2821 aagacttagc cagctataaa tctagtgatt ttttccgtca tgaattgggt tacctattcc
     2881 aaaattttgg tttgattgaa aatcaaacga ttgaagaaaa cctcaaactt ggtctcattg
     2941 gtcaaaaatt gaataaatct gagcaaacga tgagacagaa acaggcctta gaacgtgtag
     3001 gtttatccta tctgaaccta gataaacgca tttttgagct atctgggggt tagtcacaac
     3061 gagttgcctt agcaaagatc atcttaaaaa atccgccatt tattttggca gatgaaccaa
     3121 cggcttcaat agatccaacc acgtccaagt tgattatgga gattttactg tctcttcgtg
     3181 acgctaacag attaatcatc gtagcaactc ataatccagc aatatgggaa atggctgatg
     3241 aaatgatcac tatggatagt ttgcaataat gattcataat ttttctggta tttttagcta
     3301 tcaagtcctt gttttctcct aagttaatag gtaaagctta cttagaatgc aattttactc
     3361 acattagtgg aaagttggtc aaataatgtt gcgaagaaga ctagagagga tcatttgggt
     3421 cttctctttt ttggtcttta tgacgattaa tatcctcttt tacaaaggag aaattcaagt
     3481 gtctgacttg aaaaggataa gaaattcttt taccatattc tatttgtccc aaaaatttct
     3541 aaataaaaga attgtaattt ttattttcta aacttaatat tttttaaaag ctaaggacag
     3601 cgggtgcaag tcccacgtag gacttaacca gttctgccca ctgaggtcac aatttataga
     3661 aataaggagg cagatgtgaa cgtaaacgat atacctgttg aaaatgcaat agcagagtag
     3721 ggggacaaaa agagtctttt gaaacgctgg gaaggcttgg atccagtaga tcctgaatcg
     3781 ttggattgct gaggtaagag agcatcggca gttcaagcat ataatatgtc attaatccaa
     3841 gtcacaaact agccttcatc aatcttgatg gatttgaaga acgtttgaga tgaaagcaaa
     3901 gaatagcggt aaaatatagg aaatcgtgct ataatagttt aaagtaattt attctactac
     3961 gactattttg attttcttta tcatataact ggtaaaatgg aaaatattac agtttcatat
     4021 gtaaaagcaa ggtcaggaga caggctgagc gagattacag ggtaaaattg aagaggcaat
     4081 ctattcagca gagaatagct ataagccaga taccattaga aatcatttga tattattagc
     4141 attaaaaata accaaaataa gttgcagtca tatcgtttgg tctggagata gtgcttaata
     4201 tttggtgatt ttttggtgac tcgcatgatt tttaaaagac gaggggctaa aaacccttga
     4261 tacgaaagga ttttacacac atggctacta ttcaatggtt tcctggacac atgtccaagg
     4321 caaggagaca ggtacaggaa aatattaagc atgttgattt tgtgacgatt ttagtagacg
     4381 ctaggctgcc cctatcaagt caaaatccta tgctgactaa aattgtcgga gataagccca
     4441 agctaatgct tcttaataag gctgatctag cagacagcac gcatactaag aaatggcaac
     4501 aatattatga gaagcaaggg attaagacat tagctatcaa tgctaaggaa caggctacgg
     4561 tcaaaagggt caccgaggct gctaaggaat tgatggcaga taaactacgt cgcttaagag
     4621 aacgaggcat tcaaaaagaa acgctacgaa ccatgattat tggcattcca aatgctggca
     4681 aatcaaccct gatgaatcgc ttggcgggaa aaaaaattgc cacagtaggc aataagccag
     4741 gagtgaccaa gggacagcaa tggctaaaat ccaataaaga actagagata ttggatactc
     4801 cgggtatttt atggccaaag tttgaagacg aattggttgg gttaaaatta gccctgacag
     4861 gggctattaa ggatcagctg ttgccaatgg acgaggtcac gatttttgga ttgaattatt
     4921 ttaagaagta ttatcctaat cgcctattaa agcgttttaa ggctattgat ctagaggctg
     4981 acgctccaga aatcatcatg tccttgacac gtcagcttgg ctttaaggaa gactatgatc
     5041 gtttttacag cttattcatc aaggatattc gtgatggaag acttggtcag tacaccttag
     5101 atcaggttgg tgatgatgac agcaatgact attaaagacc ttaaagttcg tctagaagct
     5161 gtttctagtc tttctgatcc attttttgaa gagctaaagg cggataagcg gcttggcgtt
     5221 caaaaggctg tatctagcag aaagagggct ttagaggcta tcttaaaaga ggaagcccgg
     5281 cttgaggcga tgttgacgta tgaacaggcg ctttaccaaa aaggctttca agcgattgct
     5341 ggtatagatg aggttggtcg aggtcctctg gctggaccag ttgtagcagc ctgtgttata
     5401 ctgccaaagg gctgcaccat taaggggcta aatgattcta aaaaaattcc taaagctaag
     5461 catgaagcaa tttaccaagc cattcaaaag aaagcgttgg gaatcggtct tggaattatt
     5521 gacaaccata ccattgaccg ggttaatatc tatgaagcaa caaaattagc aatgacagct
     5581 gctattaatc agctcaaggg ctctgtgagt aagcctgatt acctgctcat tgatgccatg
     5641 acactagagg ttcctattcc tcaacaggct attataaaag gcgatgcgag ctctatgtca
     5701 attgctgcag cttctattgt ggctaaggtt accagagatc gattgatgct tgattatgat
     5761 aaggcctttc caggctatgg ctttgctaaa aatgccggct atgggaccaa agagcacctg
     5821 cagggattac accagtatgg tatcacaccg attcatcggc aaagctttga gccgataaaa
     5881 tcaatgacct tacgctaaaa agcttatttg aaggaaggta gcagcctgaa agctttcgta
     5941 gcctaagaac gatagtcact aggcgaatct acaattctgg tatttttcaa ttgaatgcta
     6001 tgtgatgagc tgctctacaa tgctcataca aaggctagaa ggcctcgctg ttttattgta
     6061 atcctgtaca agtcctaaat atgttgcaaa aagctttgtt tagtcagagc ttttttaatt
     6121 tttttacgaa taaatcatta gagaggtaca gtgatgaaca attttgaact ttataaatta
     6181 aaaaaggctg ggctgactaa tttaaatatt cttaacctta ttgactacca gcagcgtaat
     6241 aataagtctc tatcccttag agatatggca gtggtttctt gctgcaaaaa tccagtttta
     6301 tttattgaaa cctacaagca attaaatgtc gccttgttaa aaaaggaatt caatcagttt
     6361 ccgagcttat ctatcctaga taagcaatac ccattggctc tgagggaaat ctacaatcct
     6421 cctgttttac tcttttatca aggtgattta agcctgttag aaaagcctaa gctggcagtc
     6481 gttggctcta gagaatccag tgaaattggg acgcggtctg tttacaaaat cgtcaaagag
     6541 cttaagaatc actttgtcat tgtaagtgga cttgctagag gtattgatac cagtgctcat
     6601 ctcgcttgct tgaaagcagg tgggcaaact atagctgtta tcgggactgg cctagatcgc
     6661 tactatccaa aggaaaatca ccagctacag gagtttttat ctcagcgtca tctcgtgctc
     6721 agtgaatatg gggctggaga ggccgccttg tcttatcatt tccctgaaag aaaccgtatt
     6781 atcgcaggtc ttagtcgagg tgtccttgtt gttgaggcta agcagcgctc tggctctttg
     6841 attacctgtc agctagctat ggaagaggga cgtgatattt ttgtcgtacc tgacaatatt
     6901 cttaatggga catcagcggg ctgtttgaag ctgatcaaag atggtgccag ctgtgtcact
     6961 catggcagag acattctttc agaataccac tattcttaac ttttcttcct atttatggaa
     7021 aattttttgt tgacagttct taaaaaatgg gatattatgc tagaagcttt aaccataact
     7081 gttataggaa gtgtgtcaat tggtaacaaa aacagcaact aagtcaaaac aagagacgaa
     7141 aagatctgct acaaagaaaa aatcagcagc tgctaaaaaa aatctagtca ttgttgaatc
     7201 acctgctaag gctaaaacca tcgaaaaata tttgggacgt cagtataagg tcgttgcctc
     7261 ggttggtcat attcgtgatt tgaaaaaatc atcaatgtct attgattttg acaatcatta
     7321 tgagccacag tatattaata ttcgtggtaa gggtccgctg attaatgcct taaaaaaaga
     7381 agcaaagaat gctaaaaagg tttatctagc aagtgacccg gatcgtgagg gagaggccat
     7441 ttcatggcat ttatcacata ttttgggact tgatcctgat gataacaatc gtgtcgtttt
     7501 caatgaaatc acaaaggatg ccgtcaaaga agcctttgaa ggcccacgaa aaattgatat
     7561 ggatttggtt gactcacagc aggcacgtcg tgtactggat cgtattgttg gttattccat
     7621 ttcgccaatt ctctggaaaa aggttaaaaa ggggctttca gcagggcgcg tgcaatcggt
     7681 tgctctaaag ctaatcattg acagagagca tgagattaag gcctttgttc ctaaagaata
     7741 ttggtcaatt gatggtctct ttaaaaaagg gacaaaaaaa ttccaagcaa gcttttacgg
     7801 ccttaatggc aaaaagatga agctcaatac caatgatgat gttaagcttg ttttgtctca
     7861 attaagcagc gatgatttta tggttagtaa ggttgagaaa aaagaacgca ggcgtcatgc
     7921 tcctttacct tatacaacct cctcattgca gcaggacgca gccaataaga ttaactttcg
     7981 gactcgtaaa acaatgatgg ttgctcagca gctttacgag gggattagtc ttggtcctaa
     8041 tggaacacaa gggttaatta cttacatgcg tacggactct actcgtatca gcccagttgc
     8101 tcaaattgat gccgcaggct ttattgttga acgcttcggt agtcagtatt ctaagcatgg
     8161 caatcgggtt aaaaatgcta ctggtgctca agacgctcat gaggctattc gaccatctaa
     8221 tgtgaaccat acgccagagg ccattgctaa atttttagat aaggatcagc taaagctcta
     8281 caccttaatt tggaaccgct ttgtcgctag tcagatgacg gctgctgtgt ttgatactgt
     8341 taaggttaac ctcgagcaaa atggtgtcct ttttgttgcc aatggcagcc agatgaagtt
     8401 tgacggttat atggctgttt acaatgattc tgataaaagc aagatgcttc ctgaaatgac
     8461 agaaggagaa gtggttaaaa aggttacatt aacgcctgag cagcacttta cccaaccacc
     8521 agctcgttat tcagaagcaa gcctgattaa gatactggaa gaaaacggtg ttggaaggcc
     8581 atcaacctat gctccaacac tcgatgtgat tcagcgtcgt tattatgtta agctggctgc
     8641 taaacgcttt gagccaacgg aattaggcga aatagttaat caattgattg tggaattctt
     8701 ccctgatatt gttgatgtca aattcacagc tgatatggaa gataagcttg atcagataga
     8761 gatcggcaag gaagcctggc agaatgtgat tgaccaattc tacaagccat ttgttaagga
     8821 gttaaccaag gctgaaacgg agatcgaaaa aattcaaatc aaagacgagc cggctggttt
     8881 tgactgtgag ctgtgcggcc acccgatggt tgttaagcta ggtagatttg gcaagtttta
     8941 tgcttgtagt aattttcctg agtgccatca tacaaaggcc attacaaagg aaattggagt
     9001 ttcttgtcca gcttgtcagc aaggccaagt cattgagcgc aaaacaaagc gtaaccgtat
     9061 tttctatggc tgcgaccgct accctgagtg tgactttacc tcgtgggatt tgccggtagg
     9121 acggtcttgt ccgaagtcag gcgattacct tgttgagaaa aaaattcgtg gaggtaagca
     9181 ggttgtgtgt agcaatgaag tctgtgacta taaagaagag attgtaaagt aggtttgaac
     9241 tattttagca gaggtccatt ataacggaaa tatagatgat tttccattat aatggacttt
     9301 ttggtttttg tctgttataa tggaagtcat aaaaggaggg aaaatcatgc tatatatcgc
     9361 tgttattggg gatttggtcc attctaagca aattcagtcg cgttctttgg tgcaagagtc
     9421 cttaaagacc tgtctggatc agctcaacca tgatttttct tcctgtatcg tctctaactt
     9481 atctgtgact ctgggtgatg aatttcaagg cttgttgact aatgatgcgc ctgtttttca
     9541 actcattgat ttgattaatc aagccatgac aggctaccct gttaggtttg gtattggaca
     9601 gggaactatt ttgactgata ttaaccctga tattagtatt ggtgctgacg gtccagccta
     9661 ttggcgtgct agagaggcta ttcattacat tcatcaaaaa aatgattatg gcaatactca
     9721 ggtagctatc cgggctgata aggagcacaa ggatctggtg ctcaatagcc ttttagcagc
     9781 tggcgaggcg ataaaagcta gctggcgtgc tagtcaatta gaggtatttc atgcgctttt
     9841 agacttaggg atctatgaag aacaatttga ccaacagctc attggcgata cattggacct
     9901 ccaatcaagt gccttgtcaa agcgcttaaa aagcagcagt gtaaaggttt atcttagaag
     9961 tcgccatgca gctttgacct acctacaaga ataaaaagag gaaaggagcc acctatgcag
    10021 ggcttatctg attaccttta tcagcatcct attttagtgc tgctagtgat ttgtcatttt
    10081 ttatcagatt atcaccttca gagtcaggtt attgctgata agaaggagga gcagcttgct
    10141 tatctggggc tgcacttatt aggggtagct gctccattgt ttctagtggt gatgtgtata
    10201 cctaagcttt ggctaacagc gatccttatt tttagtagcc atgcggttat tgattatttt
    10261 aagccaaaat gggctcgtat cattaagctt gatcggtcgt gggtctttgt gttggaccag
    10321 ctcttgcatc ttttcattat tctggcttta gtcgctcgtg ttaatcaggc tgagatccct
    10381 gattggttac atgctcggca gttattgtta gtgcttttta tggttttgat caccaagcct
    10441 gtcaatatta tctttaagct ctgcttcaat aaattccagc cagctagtga taaaccaatg
    10501 gataccattg taggggcggg tgcggctatt ggtaatttag agcggattgt tatgggcgtt
    10561 tgtatggtgt tggggcaatt tgcttcaatc ggactggtgc ttaccgctaa gtctattgct
    10621 cgctacaata aaatctctga aagcccagcc tttgctgaat attatttgat tggatcgttg
    10681 tttagtgtct taagtgtctt tatcgcagca tggctgtgtt ttttctaaac aataacaagg
    10741 gcaggctttt gcttgctttt ttactggaaa aggcttgttt agctgctacc agcaagatga
    10801 tgaggtccgg tgaaatattt ttggctaaat tttgaaaagt aagctttgaa aagccttcca
    10861 gtaactacta cagtgaacaa gatatgtgga tagctggtat tgggcgaagg ctaatgtttt
    10921 gcagttggct ttatggagag cgtgcaggta cgggcttatc tcctttatat aaaagactga
    10981 ggctgttcag ctccttcttt tgctttgctc ttatttctgt tataataggc agggtaatta
    11041 cttgaaagaa agagttgcgg ggcaatcagt gatggataag tccccaaaga ggtattggtc
    11101 tattgtctca gtcttatatt aatgttattg gtgctggtct agctggatca gaggcagctt
    11161 atcaaattgc taagcgtggt attcctgtta agctatatga gatgcgtggt gtcaaggcaa
    11221 caccgcaaca caaaaccacc cattttgcag aattggtttg ctccaactct tttcgtggtg
    11281 acagcttaac caacgcagta gggcttttaa aggaagagct gcgtcgtctg gattcgatta
    11341 ttatgcgtgc tggcgaagcc catcgtgttc ctgctggagg agcgatggct gtagatcgcg
    11401 aaggctatgc caaggctgtt acagctgagc ttgaagctca tcctctcgtt gagattattc
    11461 gtgaggaggt tactaacatt cctagcgatg ctattacagt aattgcaact ggccccttga
    11521 ccagtgatag ccttgctgaa aaaatacatg ccttaaatgg tggtgctggc ttttattttt
    11581 acgacgcagc agctccgatt gtcgataagt caaccattaa catggatagg gtttatttaa
    11641 aatcacgcta tgataaagga gaagctgcct atcttaactg cccaatgacc aaggaagagt
    11701 ttatggcctt tcacgaggct ttgacaacag cagaggaagc tcctttaaat gcttttgaaa
    11761 aggaaaagta ttttgaaggc tgcatgccaa ttgaggtcat ggctaagcgt gggattaaaa
    11821 ccatgcttta tggcccaatg aagccggttg gcttggaata tccagatgat tacaagggac
    11881 cacgtgatgg tgatttcaag acgccctatg ctgttgtgca gctgcgtcag gataatgctg
    11941 caggcagcct ttataatatc gtgggctttc agacacattt aaaatgggga gagcaaaagc
    12001 gggttttcca aatgattcca ggtcttgagc atgctgagtt tgtgcgttac ggtgtgatgc
    12061 accgtaattc ctatatggat tcaccaaagc ttctgacaca aggcttccaa tcacgcgcta
    12121 atcacaggct tttctttgca ggtcagatga ccggtgtgga gggctatgtc gagtcagcag
    12181 cttctggact tgtggctggc attaatgctg ctcggctatt caaggaagaa gagccacttg
    12241 tttttccaaa tacaacagca attggcagcc tgccttatta tattacacac gcggacagca
    12301 agcattttca accaatgaat gtcaattttg gtattattaa agagcttgac ggacctcgta
    12361 tcagagataa aaaggaacgc tatgaagcta tcgctaaacg tgccttagct gatctggcag
    12421 cttatttaac ggtataatca ttaccccctc tctaatagtt agagaggggg tagttgttgg
    12481 ttaataatgc ttaaggtctg ttgctgcttt gatcttagta atcgtgggct gagcagcctc
    12541 gctcctaaaa aagtcaagtg aggtcttagg aaggagtagc tctaagagag cataatcatc
    12601 gtccttgatg gcctgtctgg caagagaggc gctgatgatt ttgccttctt caaaggtttt
    12661 tctagggata acctgcacat caatgctata gcaaggcagc tgcttgagca tgacagtgtt
    12721 gtaatgctgt gtgaccatgc tagtaggctc ttcgccaaca taacgactct tgatttggag
    12781 tttttctgca atgtgacgga aaatgacaat atccaattta gcttgactat caataactgc
    12841 tagctcatct ttttgaaaat aagcaggaaa ggttgcctga ctaatcatgt aaggtccact
    12901 atcgtggtat atgatatttg ctaggtgtgc agttcctttg atgattaatt cctttcggat
    12961 atggtagggg atcaggctac tgtcttgact gaccataaag agatgaacga gctcgttgtc
    13021 agcgcaggcc ttttcaatca gatgcagatg accaagggta aatggattag catttaaaac
    13081 gattgctgcg gtcttttgag gactgacctg aggcttttct agctgtgaca ggtagtgctc
    13141 aaagcccctt tttttatttt ctaaaaaaca aagagtatca tcaaccattg caatgacatg
    13201 aaagccaaga cttagcaata gaggggcagc tgatatttta gtgtagataa acagatgata
    13261 atgcccacgt gagtaggcct cctcaatcag atgtgagaca atgtgattaa gtaagccttg
    13321 tccttggtag gcttgatcaa cagctaagca gcgcaggcta ttgctgtaca aagagccagt
    13381 agcaataggc tcgccttgct cgtcaataat agcacaggta taatctaaat gagggtctct
    13441 tctaatgtgc tgtctttgta acaaacgatc aatttttgct ttttgctgct tgtcaaaggg
    13501 aaaaatatgc tgtatcaagt gctgcgtcat atgctcacct cttattacga aattatcctc
    13561 ttgcctttat tatagcacgc tatagggctt attcttaagc atcttagctg gtttatgaaa
    13621 agaatgcaca aaaaagacat caatgaccta ttgtctctga tgtcattatg atatgattag
    13681 gacttttaga taaatgatta aggtatggag gatttaagcc tgcaaaaggt ggcaataata
    13741 attctgactt atgctataat agagctattg atattaaggg ggataaaggg gctggtatgc
    13801 tttcgattct aatgacttta tttgttggga cgctgggagg gcttgttgct aagcggctga
    13861 gtattcctgc cccttttatg attggcagta tggtagctgt tgccatagct tctattttga
    13921 caaaacaggt agaggctgtc agctctatga agatttttgc tcagattatt agtggtgcct
    13981 atatcggcca aagtgtcagc aaatctgacc tgcttaatct gcccaagcta gccaagtcta
    14041 ttattagtct catgtccttg ttcacgctga atatgtttct tcttggtggg gtatttgttt
    14101 actgctttga tcttgatcct gtaacagcct tgttgagctg cttacctggt ggcattatgg
    14161 acgtttctct tatggcagtt gatatgggag caaaggctga tatagttgcg acattacagt
    14221 cggctcgact ggtcggtatg ctcttgtttc ttcctgtttg ggtgacgttt tgggtcaatc
    14281 gctttgaccc aaaagcaaaa gctactaaaa aaaagatagt caaaagtgct agctcccaag
    14341 atacaagacc ttctaggaaa gagcagctat ggaataacat tcaggtttta agcattgcta
    14401 ccattggagg tttgatcggt ttagggctaa agatacctgt aggcgctctg attgtttctt
    14461 tgcttttttc aacagcactg aaggtgcttc ggcaaacaag tcaaatgcca agtacacttc
    14521 gttatatagc gcaggttttt gctggctcta ttattggaac aagctttact caggatagtt
    14581 tgcttcaaat gggacgtctg attgttccta ttcttttact tttgagtagc tatctgatca
    14641 tcaatctctt ttttggctat atcatgtata aaaaaggtat cttggatttg caatcggcac
    14701 tctttgcctc atcacctgct ggtgcgacag acatttcact attggctggt gagcttggcg
    14761 gagatatgcc taaaatcgct ggcattcaaa tcagtcgaac cctctatact gttgtcatca
    14821 tgcccttgtt ggttaaatgg ctcattagta tatggtaaac agaaaagccc ctcagagcat
    14881 aaaccagaga tatcttacta ttaccaaata gcacatcaag ggttttgttc aggcttggag
    14941 ctgcctgcta taattgattt tctaaaaaag caaagtagag gcttagcact agcagatcag
    15001 cagtccctcc aggactgaga tgcttttgga tcagcttgtc gttgtaggct gacaaggcag
    15061 cctttaagtc agcagtgctc aaagagctgt tgtgcaatag cagcatgtcc tgtttgacct
    15121 gccgccaagc tttgatgcct cctcggtgaa tcaggttgcc atcttccaca atagacatga
    15181 ggtaaaccag cagttgcagc tgagcggtct cctgatcagt gctgcgaagg ctcttgcgca
    15241 aaaaaggtag cgccttgtga gcaattgtag gatagccctc gctggcttct cctcgagggc
    15301 cctttatacc gtaatctaga aagagcttct caccataggt gagctctttt tttaggtcta
    15361 agctaccaaa atcagtctca aggagatgag ctgttagagg cttgacaagc tgacaaatag
    15421 ccagactatc ctcctcagta aaggctgtta catgatccaa gagctgtggt tgatcagcaa
    15481 gatacattcc cgttgccccg agtaaaagtg ctaaggaaaa attgactccc ttatgggtat
    15541 tgactccctt agttgcgctg aacatggctt gttcagcctc aatgcctgag acacgcaagc
    15601 gctcaaagat cagaccagga tcttccttag catggtaaaa accaatgtct aaataagtct
    15661 taaaaaatgg tgctaaggcc agagcgctat caacaaaggt caagaagctc atgtcatcat
    15721 gagccccgtt atcaagctga tcaacaagcc caggcttagg agataaggac acttcgtaaa
    15781 gtaaagcctt tagagcaagc ctgctaatat catcaaatac cttcttagtc atcctgacgc
    15841 ctgctcattt cctgtaggat aaattttagt gagctattga ggtgctcatg cgtaataagg
    15901 gtaatttgct cgtggtcacg atttttcatg ccacgataaa tcatccaatg ctcagataaa
    15961 gcgcgttttc gtctttctag ggaagagatc gaaatttttc taaagtaaac aagataggtc
    16021 tgcaattcag tgacaatttc ttttaatctg atcatctgac tgtagctgta aatcagatta
    16081 ttaaagctgt tgaaattatc tagaattctg ttgagatcgt catcttctat aaaggtttca
    16141 caatcagcca acaaatcatg catgacctga aaatcttcct ctgtcatcaa atacatagcg
    16201 gtgcttgttg ccagtgtctc aagcgctttt ctgatttcaa agatttcaca agcatcttga
    16261 atactaacac ccttgacaat aatgcctttt ttaggaatat gctctaccaa atgctcctct
    16321 gataacaatc ctagagcgta cctgattggt gttctgctaa tatttagggc aatggaaaat
    16381 tctttttcgt tgatacgact gccagcagga atttgtctta aaataatcgt tttctttaga
    16441 gcattataaa aagctatctt caaagggata ttgcgggata ggtcaagatt atttttgact
    16501 gcttcgataa taggattcat atcatctcct taatgttaat gtcataatat tattatactg
    16561 aaaatcatta tgaatgaaaa taaccattgg gcccctgaaa agtgaaagcc atgctcgtga
    16621 aagaacatgg ctttcattag cctttattac aatccttata agagctaggt ctattgtgga
    16681 atgtaaagcg gcatttgtcc cattgcaata atggttacaa caaagataat aaagataata
    16741 atcgcgtatt tagcagcttc tttttgccat tctcccatat caagcccagt aagacgaaga
    16801 agcaggtaaa taaaggccac caatggactg agcaaatgga aggcttgtcc catcagagaa
    16861 gcaagagcca tcgccatgtt gctaaagcca tattcagctc cagcctccgc taagactggc
    16921 aaaataccat agtagaagcc atcatttgag ataaagaaag taccaggagc tgaaatcagg
    16981 gcaataacaa gtccccagaa gccagccaat tgctttggaa taatcgttgc aaagctttga
    17041 gcaagagcac tagccatacc agagccttgg aaaagtccca tgaagatacc agcagcaaaa
    17101 accagaataa caacctgaac agcatcaccg gcattatcac caatacgctt tgtttggtcc
    17161 tttaggacag gatagttaac aataagggca atacaggttc ccactgcaaa taaaagaagt
    17221 ggtgccatag caatagcctt atagaaagag ccagcaacca gccaagtgat taagccgatg
    17281 gttaagatag cattaaaggc aaagttttta ggacgacgga tagcaagcgt atctgggtct
    17341 gtaatgtctg ttagcttacg catttcctct tcggtcaaat caacaacacc aagtcttgca
    17401 cgctccttgc gtcccatgct tggcgcaacc caacaaatga cataaagaag agataaaacc
    17461 ataccaggtg cgaggtatcc aagtatttca ggtcccacac taagcacaga catggcacgc
    17521 gcagttggac caccccaagg aagcaggttc atgatagtgt tttgcaggat aatcaagaca
    17581 ccaagattca tgatgcgcat gtttaatttc ttgtagattg gtaaaaaagc agagcagcaa
    17641 atcaaggttg ttgttgtacc atcaccatta agtgaaacag ctgctgcaac aattgcagtt
    17701 gccatcaaga ccttcatcgg gtctccctta gcaaagcgaa tcattttttc agtaatcggg
    17761 tcaaacaaac cagcatctag cataatggaa aagaacagga tcgcaaacag cagcataata
    17821 cctgtcttag cagtgttatt aataccgtac atgatcatag gaccaatagc tgtcagattt
    17881 ttagcaagcc catcctcacc aacaaaggca acaaatttgg cgtctgatgt aaaatcagca
    17941 gagcctgtta atataacagc aattgtcatt atcaacggaa tcatgaccag agctgtaaaa
    18001 ggggtcattt ttttcttcat gacgacatac atgaagataa taatcatagc ataagctaga
    18061 actgttaata acatattgtt atctcctttt tgattttatg acttcagtat aaatgaaagc
    18121 gttcgcaaaa gaaatacctc catgtacgga aaaacacaaa aaaaacattt tgaaagcaga
    18181 tcctgaaaaa ataaatggtt acattaatgt ttttcaacag cagttagttg ctcttatcct
    18241 cagtaatcgc agtgtgtttc agcttttttt aaaatcagtc acatccactt tagttaacaa
    18301 tttttacaaa aatggttaac taaaataaga aaatccttga aaatgtgaaa gcgctcttag
    18361 aaagaacaca aaaaagccat tccaaaagga tgaggtggta tataataggc atagaagctt
    18421 cccatttgtg ggcaaactaa gaaaggaggt agcttatgca gttttttcaa aacatgttta
    18481 gacgctctaa gaaagaggca gctacaagcc atcaagacag agaaaataag cctgaatttc
    18541 cgttagatga ctgggagcca gtgcctagct acattgctgc agataaaaag gattatcaga
    18601 cagttagtct gattgccagt gccattgcag ctggcgagca agctagcagt cagtttaagg
    18661 taaaacgaat cctacagcgc aatcctgaga ccttaaccgt atccttaata gcatcaagca
    18721 ttgcagctgg tgtttatcca gagagtcaat ttctggttag gtccatttat agtaagaaag
    18781 taaacgttag ccacaaatag taaaaggaga aaagattatg ttgcgtaagt ttaaaattac
    18841 cattgacgga aaagagtacc tagttgaaat ggaagaaatc ggtgctccct cccaagcccc
    18901 agtagtacct cctgttcaac cagcagtagc tccagcccct gtagccgaaa aaaaggcagc
    18961 agaagctccg caagctccag cagcacctgt atcagcaggg gcagatgcaa tgccctcacc
    19021 tatgcctggt actatcttaa aggttttagt taatgttggt gatgtcgtac atgaaaatca
    19081 gcctctattg attttagagg ctatgaaaat ggaaaatgag attgtcgcct caacagctgg
    19141 tacagtcaca gggattcatg ttactgcagg tcaggtggtc aaccctggtg aaggcctcat
    19201 taccattagc tgattgctca cttatttttc agtttagaat gcagtagaaa aggaagtaca
    19261 tttgtggaaa cattaattgc aggagtaacc tccatcacta ttcctcaaat cattatgatg
    19321 cttatcggtg ctgtcttaat gtatctagga ataaaaaaag aatacgaacc aaccttacta
    19381 gttcccatgg gactgggtac tattttagtc aactttcccg gcacaggagt cttaacacag
    19441 gttgttaatg gtgttgagca agaaggggtc tttgatgcct tattcaattt tggaatcggt
    19501 acagagctgt ttccattact tatttttatc ggtattggtg ccatgattga ctttggtcct
    19561 ttacttcaaa atcctttcat gctattattc ggtgcggcag ctcaatttgg gattttcttt
    19621 gttgtcgttg tagccgtatt agctggcttt gatattaagg aagcagcttc aattggtatc
    19681 attggtgctg ctgacggtcc aacatcaatt tttgtagcaa accaattggc aaaggatttg
    19741 ctagggccta tcacagtggc agcttattct tacatggctt tggttccgat cattcagccc
    19801 tttgcgatca agctagtcac taccaaaaaa gagcgtcgta ttcgtatgac ctataaggct
    19861 gaaaacgtgt cacaattaac gaagatcctc tttcctattg tgatcacact tgtagccggt
    19921 tttattgctc caatttcgtt accattggtt ggttttttga tgtttggtaa cctgcttcgt
    19981 gaatgtggtg tcttggaccg attgtcacag accgctcaaa acgaattggt caatatcatc
    20041 agtattttac taggactaac catctctatc aaaatgcagg ccgagctttt cttgaatgtg
    20101 caaaccctgc ttattatcat ttttggtctg ttggccttta tcatggattc gattggtggt
    20161 gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa aaatcaaccc aatgatcgga
    20221 gctgctggaa tttcagcctt tccaatgtca agtcgtgtga ttcaaaaaat ggccactgat
    20281 gaggatccgc agaatttcat cttgatgtat gctgtgggtg ctaatgtatc tggtcaaatc
    20341 gcctcagtta ttgcaggtgg cttgctgctt gcttacttta gctaagaaag gacgtgctta
    20401 tgacaatcaa tatagaccat ttgatccaat cctttgagct aatggcgctt ggaatggcag
    20461 gagtgtttgt tgttttagga attctctata ttgtagcaga ggctctgatt aagctatttc
    20521 cagtagaaaa ataatagaat atgatctaaa caaggaggtc aatcaaatgg agatcaaaca
    20581 aattgctgtt gctggttcgc ttgaatccag cgacatgatg ataacaatat cacctaatga
    20641 tggtcagggg atcgttttgg aactggattc aagcgttgaa aaacaatttg gcaatcatat
    20701 cagagcatta atcaagacaa cacttgccaa cctaggtgtt gagtccgcaa caatcgaagc
    20761 tgttgataag ggagccttgg attgcaccat tcaagcaaga acaattgcgg cagtccatcg
    20821 tgctgctgga gttgagcatt acaattggaa ggagattgac tcatggaacg cttaagaaga
    20881 acgatgatgt ttgttccggg cgctaatgcg gctatgctaa gagatgcacc cttgtttgga
    20941 gcagactcta tcatgtttga tttagaggat tcagtttcct taaaagaaaa agatacctct
    21001 cgtgcccttg ttcattttgc gctaaaaacc tttgattatt caagtgttga gacagttgtg
    21061 cgagttaatg gcctagactc ttgtggtgct ttggatattg aagcagttgt gttagcaggt
    21121 gttgatgtta ttcgcctgcc aaagacagaa actgcccagg atattattga tgttgaggca
    21181 gtcattgagc gtgttgagcg tgacaatggg attgctgttg gtcgtacacg catgatggca
    21241 gctatcgagt ctgcagaagg ggtcttaaat gctcgtgaga ttgcaaaggc ctcaaatcgt
    21301 ctcattggta tcgccttagg ggcagaggat tatgtgacta atatgaaaac acgtcgctac
    21361 ccagacggac aagaattatt ctttgcccgt agcatgattc ttcacgcagc acgtgctgct
    21421 ggaatcgcag caattgatac cgtttattca gatgtcaaca atacagaagg cttccaagct
    21481 gaggtgcgtc atatcaagca attaggtttt gatggcaaat ctgtcattaa ccctcgtcag
    21541 attccattgg taaatgagat ttacacgcca accgaaaaag agattagtca tgccaagcaa
    21601 gtgatctggg ccattcgtga ggctgaaagt aaaggatcag gtgtcatctc attaaatgga
    21661 aaaatggtag ataagccaat cgtagagcgt gcacagcgtg ttatcgcttt ggcaacagct
    21721 gctggagtat taacagagga ggacatttag catggttaaa aataaacttg gtcgcgatat
    21781 tcctcaggag tatgctgatc aatatggggt atttgaagga gagctagcac gtatcactag
    21841 ctacaatgaa tcaagccgcc gcatcaagcc tgtaaaacca ggtgacagta aattacttgg
    21901 gtctattcgt gaagctattg aaaaaacagg tctaaaagat ggcatgacca tttcatttca
    21961 ccatcatttt cgtgaaggtg atttcgtcat gaatatggtt cttgatgaga tagccagcat
    22021 gggaatcaag gatttagcta tcgctccaag ctctattgcc aatgtgcatg agccattaat
    22081 tgagcacatt aaaaacggag tggttacaag cattacctcg tcaggtttac gtgataaggt
    22141 tggggcagct atttcatcag ggattatgga aaagcctgtt gtgattcgtt ctcatggagg
    22201 acgtgctcgt gcaattgcta gcggtgatat tcatattgac gttgcctttt taggggcacc
    22261 aagctcagat gaatatggta atgtcaacgg tacgattggt aaggctacct gcggctcact
    22321 tggctatgct atgatcgatg ccaaatacgc agatcaagta gtggtattga cagatcacct
    22381 agttgattat cccaacaccc caattagcat tccacaaact gatgttgatt atgtcgtgac
    22441 agttgatgct attggtgatc cacaaggaat cgctaaggga gcaacgcggt tcaccaaaaa
    22501 tcctaaagag ctcctaattg ccgaatatgc cgctaaggtt atcacacagt cgccttattt
    22561 taaagatggc ttttccttcc aaacaggtac aggaggagct tccttagcag tgactaggtt
    22621 catgcgtgag gccatgcttc aagaaaatat caaggcaagc tttgcccttg gaggcattac
    22681 aaacgctatg gtagaattgc tcgaagaagg attagttgag aaaatcctag atgtacagga
    22741 ttttgattac ccttcagcag tttcgcttgg taaaaatgct cagcattacg aaattgatgc
    22801 taacatgtat gcctcaccac taagcaaggg atcggttatc aatcaattag acacctgtat
    22861 tttatcagcg cttgaggttg ataccaattt caatgttaat gtcatgacgg gttctgatgg
    22921 tgttattcgt ggggcttccg gagggcattg tgacacagcc tttgctgcca aaatgagtct
    22981 agtgatttcg cccctgatcc gcggacgcat tccaaccttt gtagatgagg taaatacagt
    23041 aattacacct ggaacaagcg ttgatgtggt tgtcacagaa ataggtattg ctatcaatcc
    23101 aaaccgtcca gatttgatcg agcatttcaa ggacttgaag gttcctcaat ttagtatcga
    23161 ggaattaaaa gaaaaggcct actcgattgt tgggacacct gattgtatcc aatacggtga
    23221 taaggttgta gctcttattg agtatcgtga tggcagccta attgacgttg tctacaatgt
    23281 ctaaggaaat gattttcaag ggggaagctg ttaccctagc tgacatgcta agggcacgtg
    23341 aggacagaag tcttcgtcaa ggaaggcttc taacagaatt tccaaacgaa agcctgcttt
    23401 gtgtgacctt gaatattcca ggccccatta aaacgtcacc tgctttactt gaggtctttg
    23461 ataatgttat cagggcaatc ctagaaaagc tggctggcaa tcagattagc tatcagcttc
    23521 gtttgctgcc taaaacgggt tatgaatatt atcttgtgac agccttagat agtcaggcat
    23581 taaagcttaa aatgattgag cttgaggctg atttaccgat tggcaggcta atggatttgg
    23641 acgttttagt gctgacaaat caactgccaa cccctatcag tcgaacagtc ttaggctttc
    23701 ctcctcgcag ctgctatctt tgctcaaaag aggccaagat ctgtagtaga aatcgcagtc
    23761 actcggtagc agacatgcag acagcccttg tacacttact ccaatcattt tttgacggag
    23821 gcaatcagct cagttagact taacggtatt cttataagga gaatgatatg acaaaaatcc
    23881 gtataacaga aacagttttg cgtgatggtc agcaaagtca aattgctacc cgcatgacta
    23941 caaaggaaat gattccgatt ttagaaacac tagataatgc tggctatcat gccctagaaa
    24001 tgtggggagg agctaccttt gattcttgcc tacgtttctt aaatgaagac ccttgggagc
    24061 gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt acaaatgctc ctgcgtgggc
    24121 aaaatctttt gggctatcgt aattatgctg acgatgtcgt ccgcagcttt atccaaaaat
    24181 caattgaaaa cggtattgat attgtgcgca tttttgatgc cctaaatgat ccacgtaatc
    24241 tagagacagc tgtttcagca acaaaagaat tcggtggcca tgcacaggtt gctatttctt
    24301 acacaacaag tccagttcat actatcgatt attttgtagc cttagcaaaa gcctatcagg
    24361 ctattggtgc agattcgatt tgtatcaagg atatggctgg tgtgttaacc ccggagaccg
    24421 gttatcaatt agtgaagcgt attaaggaaa gtattgctct accacttgag gttcacacac
    24481 atgctaccag tggtatttct gaaatgacct atctcaaggt cgtagaggct ggtgcagata
    24541 ttattgatac tgccatatcc tcatttgccg gcgggacaag tcagccagca acagaatcga
    24601 tggttattgc tttagaggac ttggggattg ataccggagt agacatgaca aggctgacaa
    24661 aaattgccga gtattttaat actatccgag atcactacag ggcagaggga attttaaatc
    24721 ccaaggttaa agacactgag cctaagacct tgctttatca ggttcctggc ggcatgctgt
    24781 ccaatttgct aagtcagctt aaggaacagg gactctctga caaatatgaa gaggttctgg
    24841 ctgaggttcc aaaggttaga gatgatttag gctacccccc actggtgact ccgctatcgc
    24901 aaatggttgg cacccaagcc ttgatgaatg ttatttcagg tgaacgctac aaggttgtcc
    24961 caaacgaaat caaagactat gtcagaggac tttatggcca acctcctgcg ccactaggtg
    25021 aaggtattaa agagaagatc attggtgatg aagctgttat cacttgtcgt ccagcagatt
    25081 tgattgagcc acaattgccc ttgcttcgtc aagaaattgc aggctatgcc tgctgtgagg
    25141 aggatgtgtt gagctatgcc tctttccctc agcaggcgaa ggatttccta ggacgcagag
    25201 aggatccctt ttatgatatc ccagttcagt acgtcaccgt tgatatagca atggattaat
    25261 caaaaaaaaa taaaaagcaa gacaactaat aagatcaatc tcctaattat tagtcaaagc
    25321 tacctaccaa taaactcctt gatcataacc acccgtctaa tgagatgacc cccaaaaggt
    25381 cagtccaaaa tgctaaatat tgaaggctgc tacataacgg gtggtttatt tgtttagcac
    25441 ctgctgagca agatagactt aaagtcacac atattaaaaa caagctgact ctaattgaac
    25501 tgcaccccaa aagtt
//
LOCUS       DARYSY010000028        25480 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYSY010000028 DARYSY010000000
VERSION     DARYSY010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25480
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            17..262
                     /locus_tag="TVR04_001088"
     CDS             17..262
                     /locus_tag="TVR04_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1269786.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            310..891
                     /gene="amaP"
                     /locus_tag="TVR04_001089"
     CDS             310..891
                     /gene="amaP"
                     /locus_tag="TVR04_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1269787.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRAAVTEQLNGIKEGIETGL
                     TEFFGINRLVHFKVYVKDIADAKQKHSSKRRVE"
     gene            901..1089
                     /locus_tag="TVR04_001090"
     CDS             901..1089
                     /locus_tag="TVR04_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1269788.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1102..1641
                     /locus_tag="TVR04_001091"
     CDS             1102..1641
                     /locus_tag="TVR04_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1269789.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENVDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1679..1876
                     /locus_tag="TVR04_001092"
     CDS             1679..1876
                     /locus_tag="TVR04_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1269790.1"
                     /translation="MSEEKVNAKLEQAGGKIKEGFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1886..2374
                     /locus_tag="TVR04_001093"
     CDS             1886..2374
                     /locus_tag="TVR04_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1269791.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2532..3173
                     /locus_tag="TVR04_001094"
     CDS             2532..3173
                     /locus_tag="TVR04_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1269792.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3293..3841)
                     /locus_tag="TVR04_001095"
     CDS             complement(3293..3841)
                     /locus_tag="TVR04_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1269793.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLKNDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQIFKDFIYQFLTTIDGFQEIIINHYQIPYHYALEVYLASIESLISYWISHG
                     CQETTDDMTAIILKTVGFEKAI"
     gene            3964..4665
                     /locus_tag="TVR04_001096"
     CDS             3964..4665
                     /locus_tag="TVR04_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269794.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4677..7316
                     /locus_tag="TVR04_001097"
     CDS             4677..7316
                     /locus_tag="TVR04_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1269795.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQTITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQLLQDNGQERYEEMLNDLNRSLKDSKAKLEEQRTILKASEDQL
                     ALLSGHALEQAQDQLKQGREELAKKETSLLEMADKQRAAMIKPTYASYSRSTLPGGEG
                     YQAYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGVLAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLPAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDELELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPAYLITTAKANPAAVKDVASQLLAMPAVQAVSQHSSIAATV
                     TEIVASLDQVMTLLVLLSVLLALVILYHLTNINISERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSTVGILIGFWCGNYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7391..7987
                     /locus_tag="TVR04_001098"
     CDS             7391..7987
                     /locus_tag="TVR04_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1269796.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYRQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEKEMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVSRAEQEWQFIQNEIQKGLG"
     gene            7997..8959
                     /locus_tag="TVR04_001099"
     CDS             7997..8959
                     /locus_tag="TVR04_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1269797.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARNRLLSFFLAFAVAVSLFALFGFGLLSLGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILLNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVNQLTSQSRESILLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLVQDLERFILLKVEFYRDYKEEQA"
     gene            9056..10306
                     /locus_tag="TVR04_001100"
     CDS             9056..10306
                     /locus_tag="TVR04_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1269798.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQLLAQVRGQEFDKELAQRLESEM
                     KLQEARANSRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDSNGVEILSIMFEMKNEADTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEQFKHAFAKNYQSASNNFKKAIDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            10415..11296
                     /gene="truB"
                     /locus_tag="TVR04_001101"
     CDS             10415..11296
                     /gene="truB"
                     /locus_tag="TVR04_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1269799.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRRLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTAVSSSLTEAMVD
                     EAMTQFVGQITQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYVRTLAVDLGRALGYASHMSWLVRTASSGLTLDQSYTLSEIA
                     DLLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLVAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            11310..12242
                     /locus_tag="TVR04_001102"
     CDS             11310..12242
                     /locus_tag="TVR04_001102"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1269800.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLQHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRARHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLIKAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGERYRSMTSIGKNITFGGKELRLEANIFGFNEDIYGETLEIIWLDR
                     IREMTKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            12285..12689
                     /locus_tag="TVR04_001103"
     CDS             12285..12689
                     /locus_tag="TVR04_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1269801.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            12691..12969
                     /locus_tag="TVR04_001104"
     CDS             12691..12969
                     /locus_tag="TVR04_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1269802.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVRAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            12959..13735
                     /locus_tag="TVR04_001105"
     CDS             12959..13735
                     /locus_tag="TVR04_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1269803.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFGLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNEYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGEQPDFQSRQKVMFVPKSKLATIQSLLQINENNQ"
     gene            13752..15059
                     /locus_tag="TVR04_001106"
     CDS             13752..15059
                     /locus_tag="TVR04_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1269804.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQLV
                     CLDPPIPDTLWGYYGRVSGKSPDHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVVVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAMSYWHKDYPAACANLQRSILSEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSNYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DSLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLAINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            15197..16063
                     /locus_tag="TVR04_001107"
     CDS             15197..16063
                     /locus_tag="TVR04_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1269805.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            16074..17009
                     /gene="pstC"
                     /locus_tag="TVR04_001108"
     CDS             16074..17009
                     /gene="pstC"
                     /locus_tag="TVR04_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1269806.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILIF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPTSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            16999..17886
                     /gene="pstA"
                     /locus_tag="TVR04_001109"
     CDS             16999..17886
                     /gene="pstA"
                     /locus_tag="TVR04_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1269807.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            17903..18706
                     /gene="pstB"
                     /locus_tag="TVR04_001110"
     CDS             17903..18706
                     /gene="pstB"
                     /locus_tag="TVR04_001110"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1269808.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            18720..19478
                     /gene="pstB"
                     /locus_tag="TVR04_001111"
     CDS             18720..19478
                     /gene="pstB"
                     /locus_tag="TVR04_001111"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1269809.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            19549..20202
                     /gene="phoU"
                     /locus_tag="TVR04_001112"
     CDS             19549..20202
                     /gene="phoU"
                     /locus_tag="TVR04_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1269810.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINEFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20437..22974
                     /locus_tag="TVR04_001113"
     CDS             20437..22974
                     /locus_tag="TVR04_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1269811.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIESSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAVGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GALRFNTENTAHYITDYQGQLFYSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSVEQSFNRLISSIFQEDFSQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFETADLVDAYFDVYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGIKEISARVTLIDSEKEAIANALSQY"
     gene            23393..24067
                     /locus_tag="TVR04_001114"
     CDS             23393..24067
                     /locus_tag="TVR04_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1269812.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLVY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            24060..25370
                     /locus_tag="TVR04_001115"
     CDS             24060..25370
                     /locus_tag="TVR04_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1269813.1"
                     /translation="MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISANQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARTRQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
BASE COUNT         7424 a         4635 c         5866 g         7555 t
ORIGIN      
        1 attgaggaga tttattatgg gaattatttg gacattaatt gtgggtgcac ttatcggtgc
       61 tattgccggt gcgcttacta aaaaaggcgg atcaatgggc tggattgcca atatcgctgc
      121 aggacttatt ggatcatacg ttggtcaagc tttgtttggc agctggggtc taacattagc
      181 tggcatggca cttttcccat caatcattgg tgctgttatc gttgttatca ttacttcttt
      241 tgtactaaat aaatcaaact aagggcattt ctatcattat agagatggtt gagtaggaaa
      301 gaggttttta tgtcgaaatt tttaaaaatt agctatagtc tcattggctt agtcctattg
      361 acggtctttg gtggcgtgat agccataact ggagattata ttaggctacc tattggctat
      421 caatggcttc actgggatat gaattggctt cctaaattcc taaatccggc cttatattat
      481 tattactttt gggcagctat cgctttattt ctgataacag tgctgatcct tcttgtgatt
      541 atcttttatc cacgcaccta tactgagatt cagctggcta aggataaagg aaccctgctt
      601 ttgaaagggt ctgctattga aggctatgta gcagctgcta ttaaagcagc agggcttatg
      661 tcaagcccaa gagttaccgc taagctgtac aagcgtaaat ttaaggttaa tgtcagtggg
      721 caattagctt ctcgcgcagc tgtcactgag cagctaaatg gcattaaaga aggaattgag
      781 actggtttaa cagaattctt tggtattaat cgacttgtcc atttcaaggt ttatgtcaag
      841 gatattgctg atgctaagca aaagcatagc tctaagagac gtgtagaata ggagattatc
      901 atggcatttt atgaacggtt taaataccct attattggtg gtctgatagg gctgatagct
      961 gctgtattac tgatgacctt tgggttattt aaaacactgc tggcaattat tttcattatt
     1021 ttaggagtat atggtggcct gtatgccaaa aagacaggta ttatcgatca attgatcaaa
     1081 cgtaactaaa ggagatttat catgactgaa acttacatta aaaacacaac tcataaagaa
     1141 ccaacttcag ctgttcgtgg cgaattgacc tatgatgaca aggtcattga aaagatcgtt
     1201 ggcttggctc ttgaaaacgt tgacggccta ctaggtgtta atggcggctt tttggccaac
     1261 ctaaaagaca agcttgttaa tagtgattct gttcgtgatg gggttaatgt tgaggttggt
     1321 aaaaaagagg ttgcggttga tttagacatc gtagcagaat accaaaagca tgttccaacc
     1381 atttttgatg cgattaaatc tgtcgtagaa aatgaagtca agagaatgac agatttagag
     1441 gtgattgagg ttaatgttaa ggttgttgac attaaaacca aggagcaatt tgaagctgat
     1501 aaggtcagcc tacaggataa ggtgactgag gtagctcgct caacctctga atttacaagc
     1561 aagcaggtag acaatgttaa ggcatctgta ggtgcaggtg ttgaaaaggt ccaagagcaa
     1621 actgagccac gcgttaagta agctaggctg tcaaacgata gaaatagagg aaatcataat
     1681 gtcagaagaa aaggtaaatg caaaattgga gcaagcaggc ggtaaaatca aagaaggctt
     1741 tggaaaggtg actggtgata aatccttaga aaccgaaggg aaggttgatc aagcagccag
     1801 caaaatcaaa gaggtagctg ctgatgctaa ggacgctgtc aagggctttg ttaagggcct
     1861 taagcaagat aaataaggag ttgtaatgaa agcaaaggac ataaaaagta cgttgaccta
     1921 cgatgataag gtcattgaaa aaatcgttgg acatgcttta gaaaaggtca gtggcttatt
     1981 agcagtcaat ggtggctttt tctcaaacat taaaaataac ctcgtgaaca gtgactctgt
     2041 tcgtgatggg gtgtctgttg aggttggcag caaggaagtg gctgttgact tagatattgt
     2101 tgttgaatat ggtaaggata ttccagcaat tgttgagtct atcaaggcta ttgtttttca
     2161 aaatgtcgat agcatgacac atttgagggt cgttgaagta aatgtgaacg ttgttgatat
     2221 tagaaccaaa gaagagcatg aggctgccag cgtcactgtt caagacaggc taacagacgc
     2281 agcctcagca acctctcaat ttgtagctga gcaagcagac aaggtaaaag aaactgtctc
     2341 taaaaccaca gataataacg agacagtaga ataaaactca acaactaaaa ctcctgttaa
     2401 tgacatattg tgggctggtg tgatgaccag ctctttttat cagtgcttga acaatgttat
     2461 gctattgtat tctctgtgaa aatgtgattt aatgggaatg gtatcatttg ttaaaaagga
     2521 gtataattat catgactagt aataagagag agattactaa ttccaagtat caaaagattg
     2581 ccatttcagt tgctgaaagg attgccaatg gcgaatatga ggtgggagaa aagctaaagt
     2641 ctaggacaac cattgcttca acctttaacg tttcgcctga aactgctaga aagggtctga
     2701 atattttagc tgatttgaag attttgactt taaagcatgg gagtggtgcc attgtcttgt
     2761 ctaaggaaaa ggctattgat tttctgaacc aatacgaatc cacccattcc atcgctgtta
     2821 tcaaagaaaa cattcgccat aatattcgtg agcaggaaaa ggcaatggag catttaacag
     2881 tgctggttaa cgagtttctg atgcaaagcc aatcaatcag caagcaatac ccgctggcac
     2941 cttacgaaat tatttgtagt caggattcag agcattttgg ccaatccatt ggtgatttga
     3001 acatttggca tcaaacggga gcgacgattg tagctattga gcatgatggc caattcattg
     3061 tttctcccgg tccttacgct gttatcgaaa aaggtgatca tatttacttt gtcggtaatg
     3121 aggacgtgat ttctagaatg aaaacctttt ttaatgttag aaagggtctg taatcgcaaa
     3181 aaaaaaacac agagctgctt taaggtgata gtgatatcac gaggaagtgt ctctgtgttt
     3241 ttgtgtcatc aggctaaggc tttctagtgg cttatagctc tgactgaagc tcctagattg
     3301 ctttttcaaa gccaacagtt ttcaggataa tagctgtcat atcatcagtt gtttcttggc
     3361 agccatgact aatccagtag ctgatcagac tttcaatact ggctagataa acctcaagcg
     3421 catagtgata agggatttga tagtgattga tgatgatttc ttggaagcca tcaatagtgg
     3481 tcaaaaattg ataaataaag tccttgaata tttgtgaaaa attcaaataa ctggagttag
     3541 ccatagcagc aataaaggga agattatcaa tgatataagc gagggcttcc tttagaacga
     3601 gtctagtatc tgtaaaaata tgagggtcat ttaggagctg gtataaatcg tctaaggtgt
     3661 catttttgag atgagtcatc atatcatgtt tatccctgta atgcaggtaa aaggtgcctc
     3721 tattgacacc agcttttttg gttaagtcag aaacggtaat ggtctcaaag ctcttttctg
     3781 tcaaaagact gacaagtgcc tgcttcaaat aggccttggt tggtgtgtgt cttgttgtca
     3841 tcgactcatc tccttaaatc aacaaatgct gcttatctgt tcttgttaaa gtcttgagga
     3901 cattatataa taaggctagt ataaaatcaa caaggtgttg atataaagga ggtgacatga
     3961 tcagtgtcct atattgaaat gaggtcctct tcaaagacct accagattgg agaaacaact
     4021 gttaaggcta atgatgaggt atcctttgag attgaaagag gggagcttgt gatcatttta
     4081 ggagcctctg gtgcaggcaa gtccacagtg cttaatattt taggcggcat ggatagcaat
     4141 gaccaaggtc aggtcataat agacggcaag gacatctcga cctatagtaa aaaggcattg
     4201 accagctacc gtcgttacga ggttggcttt gtttttcaat tttacaatct ggtgccaaat
     4261 ctgacagcaa aggaaaatgt tgagctggcg gctgatattg tggcagatgc acttgatccg
     4321 actactgtct taaatgaggt ggggctagga ggacgtttgg agcatttccc agcacagcta
     4381 tcaggaggtg agcagcaaag ggtgtctatt gctcgtgcct tggctaaaaa tcctaagttg
     4441 ttgctttgtg atgagccaac aggggcttta gattatcaaa ccggcaagca aattttaaga
     4501 ttgcttcaag atatggcgca cgacaagggc aggacagtta ttgtggtgac gcataatact
     4561 gctctagcgc ctattgctga tcgggtcatt tatatgcatg acggtcgtgt gaccaagaca
     4621 gtgcttaata agcagccgct tgatattgat aggataacgt attgagaggt gcctagatga
     4681 aacaaaaaac cttatggaag gatagttttc gagcaataaa ggctagtaag gggcgttttt
     4741 tgtccttgct atttttaatg gctctaggct cctttgcctt ggttggctta aaggtggctg
     4801 gtcccaatat ggaaaaaact gctagtcact atctagagga gcatcaggtt atggatctta
     4861 gtatcctagc ctcgcatggc ttttctgata gagataagca agaattagcc tctcttaaaa
     4921 atgcaagact agagtatgcg agctttgttg atggtgcttt tgatcaccag aggaaggcta
     4981 ttaggcttta ttctatgcca caaagcctat ctcaggccag cttggtcaag ggagattacc
     5041 ctagcaaggc tagcgacatt ttgctatctg aggctttatc aagccgctat cggcttgggc
     5101 aaacaatcac gataagccta aaaacaaagg gattgctaaa gcatagatcc tatcgtgttg
     5161 tcggctttgc tcattctcca gaaatatggt ccaaaacaaa cttaggtgtt tcctcagcag
     5221 gggatggtaa tctctatgcc tatgcctacc ttcaccctag tgcctttcag caagggcaca
     5281 atctcttacg cattcggtat gatgatttaa gagggttgaa tgccttttca acccaataca
     5341 atgaacgatt gctacaacac caagctgagc ttgatcagct tttgcaggac aatggtcaag
     5401 agcgttatga agaaatgctc aatgacctta atcgcagctt gaaagatagt aaagctaagc
     5461 tcgaagagca aaggactatt cttaaggcga gtgaggacca gctggctttg ttaagtggtc
     5521 atgccttaga gcaagcgcag gatcagctaa agcaaggccg ggaagagtta gctaagaaag
     5581 agactagttt gctagagatg gctgacaagc aaagggcagc gatgatcaag ccaacctatg
     5641 ctagctatag ccgctcaacg ctgccgggtg gtgagggcta tcaagcctat gctacctcaa
     5701 cacagtccat atcacatgtc ggaaatatct ttcctgttgt tttgtatttg gttgcggctc
     5761 tagtcacttt tacaacaatg gctcgctatg ttgacgaaga aagaacaaac tctggcttac
     5821 taaaggcaat aggctattct gattgggata ttaccaagaa atttctgcta tatggtgttt
     5881 tagcagcctt gttgggtact ggattaggtg ttttaggagg gacttatttt ttatctcgac
     5941 tcatctcagc tattctaaca gatgctttga ctatcggctc tactcagctt tatttttact
     6001 ggagctatag tgtggttgca gtgcttttag ccttgttatc tgctgttttg ccagcttata
     6061 tggtggtgag acgtgagctt tttctcagac cctcacaatt gttgctgcct aagcctccta
     6121 gtagcggggc aaggatttgg ctggagcatg tctcctttat ctggcggcgt ttatccttta
     6181 cctataaggt tacttttcga aatatctttc gatataagca aagaatgctg atgacagtaa
     6241 ttggagtagc aggttctgtt gcgctcttat tttccggctt gggcattcaa tcctcacttg
     6301 ctaatagcct aagctatcaa tttggcaagc tgacagccta tgacatgctc gtggtagagg
     6361 ctccaacagc agaagctcat gataggcagg agctggcaca atatttgaag gcagatcaga
     6421 ttgctagtaa gaaagagatt tattacgcta acttatcact aaagataaaa gacttagaca
     6481 acaagcaaac agtgtcgttg atttctagcg atcagagcac tctatctccc tattttagct
     6541 tgattggtgc tgctgaccga aaaaagctag accttccaag tactggagtg cttatctcaa
     6601 aaaagcttgc tgactattat caggctcatg caggagatga gcttgagctt gaagctagta
     6661 acggtaaacg ctatcagtta agagtgagtc aggttattga catgactgtt ggtcattact
     6721 tgttcatgtc taaatcttat tatcagcagg tatttcggga tatggaggct tcgccagcct
     6781 atttgataac aacagcaaag gctaatccag ctgctgtaaa ggacgtggct agtcagctct
     6841 tagcaatgcc tgcggttcag gctgtgtcac agcatagtag tattgctgct actgtgaccg
     6901 aaattgtggc ttctctggat caggttatga cgcttttggt gcttctatca gttttactag
     6961 ccttggtcat cttgtatcat ttgactaata tcaatatttc tgagagggtt agggaattat
     7021 caacgataag ggtcttgggc ttttatgata aggaggttac cttatacatt tatcgggaaa
     7081 ctatgctcct atccactgtt ggtattctga ttggtttttg gtgcggcaac tatttgcacg
     7141 cctatatcat gaaggtgatt gctaatgatt ctatgagctt tggtaggaca gttgatgctt
     7201 atgtttacct agtacctgtt ggggctattg tgcttttgtt gattgtgctt ggctatatgg
     7261 ttagctaccg gctaagaaag attgatatgc tagaggctct aaagtctgtt gattagggta
     7321 aaatagcact tgaaaatcct ttaacaatat ggtagtatta aaatactata atttgataga
     7381 aggatacttt atggaagcaa tgatagctgc ctatttggct gatcatagag aaaagatacc
     7441 acttggtcag gttgttgatt gctttaaggg gaaggctgtt tctcgtaagg ctgaggctgg
     7501 tgaatttggt ctgattaatc tgtctgatat gggacagcta ggaattgact atcgtcaagt
     7561 cagagccttt catatggata gacgacaact gttgcgctat atcttagagg atggagatgt
     7621 cttgattgcc tcaaagggga ctgttcagaa ggtttgtgtt tttcataagc aagaaaagga
     7681 aatggtagcc tcctctaata tcacagtgct gcgtcctcag agggttttgc gaggctatta
     7741 tatcaagttc tttttggagt ctgctattgg tcaagccttg ttaaaggcgg cggatcatgg
     7801 aaaggacgtg attaacctat cgaccaaggc cttgcttgat atccctgtac cagtgattcc
     7861 tttggttaag caggattatt tgattaatca atatttgcga ggcctgcatg actatcaacg
     7921 aaaagtaagc agagctgagc aggagtggca gtttattcaa aatgaaattc aaaaaggtct
     7981 gggctagggg tagagtgtga gcttaattga acgaacaata aaaatgctat tagcaacgat
     8041 ggctgcaatc tttcttgcct ctcagctaca gctgtcttat gctatatcag cgggaattat
     8101 tgccctgtta ggtgtgctag acactagaaa atctagctta attgttgcta gaaatcgtct
     8161 gctgtctttt ttcttagcct ttgctgtagc ggttagtcta tttgccttat ttggctttgg
     8221 tctgctttcc cttggcttgt atctagcgct aaccattcct ttgctttatc agctgaaaat
     8281 agaggcaggt cttgttccta tcactgtctt ggtgactcac ctgatgtctg agcagcgtat
     8341 tgatttgtca attcttttaa atgagctgtt gctgtttttg attgggacgg gtcttgccct
     8401 tcttgttaac ggctatatgg ggtctcagga gcatcgccta cgcttgtacc accaaaagat
     8461 agaagatagc ttaaaggcta tcttgtaccg ttttgaatcc tttttgttag aaggccaagg
     8521 acaaaacgag ggacagatga ttaaggaatt agagcttagc ttagatgagg cgctaaagct
     8581 ggtttatcgc gaaaggcata ataccctctt ttatcatacc aattatcagg tgcattattt
     8641 tgagatgaga cgtcatcaaa atagattgtt ggcgcaaatg gccttaaatg tcaaccagct
     8701 aacatctcaa agcagagaaa gtatcctgct ctcccatctt tttcatgaga cagcccgtca
     8761 gctgagtgag aagaattctg ctttgacatt gattgatgat attgagcaat tgcttgaggt
     8821 ctttaggcaa agagagctgc ctcagactag agaggaattt gaaagacggg cgattctgtt
     8881 tcagctggtg caggatttgg agcgctttat tctactgaag gtagaatttt atcgtgatta
     8941 caaggaagag caggcatagt agctgcttgc tgctgtgatt aagagtctgg aaaaatcatt
     9001 ttctaggctt tttttgctat aatggcagtg agataattgc aagaatggag aaatcatgaa
     9061 agaactaaaa tgtcctcatt gccatacctt atttacggtc aatgagtctg attatagtca
     9121 gctcttagca caggtgcggg gtcaagagtt tgacaaggag ctggcacagc gtctagaaag
     9181 tgagatgaaa ctgcaagaag caagggccaa tagccgcttc caagaggtgc ttactaaaaa
     9241 ggagcaggct attcaaagcc tgaccaaccg cttggagcgt attgagcagg aacaggccta
     9301 tttgaggcag caggagctag cccaaaagga taaggagctc ctagagctcc acaatcagct
     9361 agataagcta gagcttgagc agcaatcaag gctccagtct gcccttacag ttgttgaaaa
     9421 ggagcgtgat cacctaaaaa atcagctcgt gctgcaggaa aaagaaagcg aactttctct
     9481 agcttctgtg cgcagtgatt atgaggtgca gttaaaggct gtcaatgagc aggttgagtt
     9541 ttacaagaat tttaaagcgc agcagtcaac caaggctatt ggagagagct tagagctgta
     9601 tgccgaaacc gagtttaaca aggttcgcag ctatgccttt ccaaatgcca gttttaccaa
     9661 ggacaatcaa gtgtctcatc gaggctcaaa gggtgattat atttaccgag agctagacag
     9721 taatggtgtt gaaattctct caatcatgtt tgaaatgaaa aatgaggctg acacgaccaa
     9781 gaccaagcat aaaaatagtg atttctttaa ggaattagat aaggatcgcc gggaaaagaa
     9841 ttgtgaatat gctgttcttg ttaccatgct tgaagcagac aatgattatt acaatgcagg
     9901 aattgttgat gtcagtcatg actatgacaa aatgtatgtg gttcggcctc agctctttat
     9961 tcatctcatc ggattgctgc gtaacgctgc tcttaatagc ttaaaatata agcaagaatt
    10021 ggcgcttgtc agggagcagc acattgatat tacacatttt gaggaggacc tagagcagtt
    10081 taagcatgct tttgctaaaa actaccagtc tgcaagcaat aactttaaaa aagccattga
    10141 tgaaattgat aagtccatca agcgtatgga ggaggtcaag cgctttctaa caactagcga
    10201 aaatcagctg cgtttagcca ataacaagct agatgatgtc tctgtcaaaa aactaaccag
    10261 aaataatcca accatgcgcg ataagtttca agcaatcaag ccctagaact atctcaatca
    10321 ggcttattga tagaggcttt gttgcttgtc aaaagcctta tgaaatggtt ataatagata
    10381 ggctaatgat caaaacaata aacgaaagta acacatgata aacggaataa tcaatttaaa
    10441 aaaagaagca ggcatgacat cacatgacgc tgtttttaag cttagaaggc tattacaaga
    10501 aaaaaagatt ggacatggag ggacgcttga tcctgacgtg gttggtgttt tgcctatagc
    10561 agtggggaag gcaacgcgag ttattgaata catgacagaa gcaggtaaaa cctatgaggg
    10621 agaggttact cttggctatt caacgacaac agaggatgct agtggagaga ttgttgacca
    10681 aacagcagta tcctcaagcc tgactgaagc gatggttgat gaggcaatga cacaatttgt
    10741 tggtcaaatc actcagattc caccgatgta ttctgcggtt aaggttaatg ggcgcaagct
    10801 ttatgattat gcacgagctg gtgaagcggt cgagcgccct aaaagacagg taacgattga
    10861 ccagtttgag cggacaagtc ccctgacctt tgcaggtggt ctttgccgat ttagctttag
    10921 ggtgagctgt agtaagggga cctatgttcg gaccttggcg gttgatctag gaagagcgct
    10981 tggctatgca agccatatgt cttggttggt tcggacagct tcttcggggt taactttaga
    11041 tcagtcctat accttgtcag agattgctga tctgctggat aaaaaggaca tgagcttttt
    11101 attgcctatt gaatatggtg ttagtgattt agccagagta gtcgttaatg actgggagct
    11161 gagagagctt tcctttggta gaaaaatcgc tttatcatgt gaggaaaatc tattagtggc
    11221 tttttatcag gacagcttga tcgctatttt agaaaagcaa gaagggcttt acaagccaag
    11281 aaaggttttt atttagagaa gattgatata tggatataca acacattaaa agctatcagg
    11341 agattgatga atcagctgat accgttttag tcttaggcta ctttgatggt ctgcaccgag
    11401 gtcacaaggc tttatttgat aaggcaaagg aaatatcacg tcaggaaagc ctaaaaatag
    11461 tcaccttgac cttccatgag tcccctcagc tggcctttac acgcttttct cctgattttt
    11521 tacagcacat tacttatccg gaaaagcggt atgaaaaatt tgctgagtat ggtgttgata
    11581 agctttattt gcttgatttt accacgtcat tttcaaaact atcctctgat gatttcattg
    11641 accactatat tgggcgctta agggcaaggc atattgttgt aggctttgat tatcactttg
    11701 ggtgtgatca cgcagatagt cattacttag cgaaacgaat aaagggaacc gtttatagca
    11761 tttcagaggt caaagaggac cagatcaaaa tctcatcaac acgtatcaga agcctgatta
    11821 aagcaggaga tgtcgctaag gctaatcagc tgcttggcta cgagctttca acaagaggaa
    11881 tggttgtgca tggtgatgcg cgtgggcgaa ccattgggtt tccaactgcc aatcttgcac
    11941 ctattgatag gacctatctg ccagctgatg gtgtttacgt gacagatgtg ctggttagag
    12001 gagagcgcta tcggtctatg acgagtatcg gcaagaacat tacctttggt ggcaaagagc
    12061 tgcgactaga ggcaaatatt tttggcttta atgaagacat ttatggagaa actcttgaaa
    12121 ttatttggct agataggatt cgtgagatga ctaaatttag tgatgttagc acctttatca
    12181 gccaactaaa gcaggataaa gaagctgcca taaattggaa aaaagatagc caaggctatt
    12241 aaatttttgt ataataaggt aagcacaatt aacagaggaa aagtatgatt accttatttc
    12301 tatcaccaag ctgtactagc tgccgtaagg ccagagcctg gctcaccaag catgacgttg
    12361 actttcaaga gcataatatt attaccagcc cacttagtcg tgaggagctg ttagcgatcc
    12421 tatcctttac tgaaaatgga acagaggata ttatttcaac acgatcaaag gtttttcaaa
    12481 aattggatat tgacattgat gagctgtcta tcatggattt gattgatttg atcgcaaaga
    12541 accctagcct tcttcgtagg ccaatcatta tggatagtaa gcgtatgcaa attggcttta
    12601 atgaagatga gattagggcc tttttgccaa gggattatcg taagcaagaa ctgcgtcaag
    12661 caaccataaa ggcagaaatc gagggataac atgtcagatc attatcatta cccacttgat
    12721 gtaagctgga gcactgaaga gataacatca gtgcttcatt ttttaaatca ggtagagtta
    12781 gcctatgagg ctaaagtaag agcagaggag ctgctcaaaa gctatgctgc ttacaaggag
    12841 attgtaagaa gcaaatcaca ggaaaagcag attgaccgcg aattccaaca agccagcggc
    12901 tattcaacct atcaagctgt caaaaaagcc agagaaattg agaaaggatt cttttccctt
    12961 ggaagataaa tacgcatttg ctaaaacgat catcaaagag gctggccttc tgattaagga
    13021 tagaatgaaa gatagcttag ccattgaaat caagacgcag catgatgatt tagtgaccaa
    13081 tgtagatcaa gagacgcagg atttcttaat tgctaaaatc aaacaggcct atcctagtga
    13141 ccatatgatc gctgaggagg gcggtatctg tcatgctatt acagatggca aggtttgggt
    13201 gctggatcct attgatggta cggtgaattt tattgtacag aaagccaatt ttgcgatcat
    13261 gatggcttat tatgagaatg gcgtcggaaa atttggtctc atttatgatg tcatggcaga
    13321 tcagcttttt tcaggtggtg gagactttgc tgttacttta aatgatcaag tcttagcatc
    13381 ttatcaggat aagccgcttg atcgcagctt aattggctgc aatgcaggta tgctttcaag
    13441 gaacgagtac aacctgcacc agctcattga tcaaacccta ggcgtgaggg tttatggcgg
    13501 cgcaggcatt tgcatgacca aggtgttaag gcagcagcta atggcttatt tctcctatat
    13561 tcaaccttgg gattatgcag cggcagccat tatgggcgaa agccttggct atgtcctgct
    13621 gaccttagag ggagagcagc cagactttca gtctaggcag aaggtgatgt ttgttcccaa
    13681 gtccaagcta gccaccattc aatccctgct gcaaataaac gagaacaatc agtaagatta
    13741 agatgaaaag catgcaatta ccaaacgatt ttattgaaaa ataccaacag ctgttaggct
    13801 cagaagcaaa agcttttttt gagagctttg atcagcctgc tatcagtgcc tataggataa
    13861 atcccttaaa gcaccaattg gtctgccttg atcctcctat tcctgataca ctatggggtt
    13921 actacggcag ggtatcagga aagtctcctg accatgtgtc aggtgtggtg tattcacaag
    13981 agcctgctgc tcaaatggtt gctcaggtag cgtcacctgc caaggggact agagtgttgg
    14041 atttggcagc agcgccaggt ggcaagtcaa ctcagttact tgcctatcta gagaatacag
    14101 gacttttagt gagtaatgag atttcgacca agcgaagtaa ggctttagtt gaaaatatag
    14161 agcgctttgg tgctagaaat gttgttgtga caaatgagtc cgctgacagg ctggcagctg
    14221 tttttccaga atattttgac actattgtct ttgatgggcc ttgctctggc gagggcatgt
    14281 ttcgcaagga tccaaatgct atgagctact ggcacaagga ttacccagca gcatgtgcta
    14341 acctgcaaag gtctatttta tcagaggcga tacctatgct aaagccaggt ggtcagctga
    14401 tttattcgac ctgcacctgg tcgcctgaag aaaacgaaga ggttgttcgc tggctactag
    14461 aaagctatga ttttcttgag ctggagcata tccctaagat caatggtatg gcagagggaa
    14521 tcggtatgcc acaggcagct agaatgtacc ctcatcgctt taaaggagag ggacagtttg
    14581 ttgccaaatt aaaggatact agatcaacga tttcctcttc aaactacaaa tctccaaggt
    14641 ctaacctcac tcaagagcag ctgaggctgt ggcaggattt tgaaaaaaat catttgaaca
    14701 taaccttgtc tggcctatta caggtctttg gtgatcgttt atacctgtta ccagatagct
    14761 taccctgtct tcgatcgctt aaaatagcaa gaaatggtct ggaattaggc acttttaaga
    14821 aaaaacgctt tgagccttcc tatgctctgg gcttggcatt aagacctgaa gaggtcagct
    14881 tatctgttga gattaacgaa gaggactttg tcacatacgc ctcaggaaat accattacct
    14941 taccagaatc ttatgctaca gattggtatc agctggccat taacggaaat ggtctgggct
    15001 ttgctaaaat agttggtcgc acccttaaaa atagcttccc taagggctta cgtttttaag
    15061 gaatggcata ccattaaatt tttataaatt taaataaaac ttcttccaaa gcattgttag
    15121 atatgttact ataaagaata tgctgaagct taattcttcg ctataaacct ttatttttat
    15181 gaataggaat agaataatga aatcgaaaaa gaaattcttt ttgttaagtc ttttagcctt
    15241 gtcggctttc tttttgtcag cctgctcaag ctggattgat aagggagaat ccataacagc
    15301 ggtaggctca acagcattac agcccttagt agaggccgca gctgatgagt ttggaagcaa
    15361 taacctcgga aaatctgtta atgttcaagg aggcggctct ggtactggct tatcacaggt
    15421 gcaatcaggt gctgttcagg taggcaatag cgatgtcttt gcagaagaaa aggacgggat
    15481 tgatgctgct aagcttgttg atcaccaggt tgccgtagca ggacttgctg tcattgccaa
    15541 tcctaaggtc aaggtatcta atctcacaag caagcagcta caaaagattt tttcaggtga
    15601 atacactaac tggaagcagg ttggcggaca ggatctagct atttcagtga ttaatcgagc
    15661 agcaagctca ggctcacgtg ctacctttga tagtgtcatc atgaagggtg ttactgctaa
    15721 gcaaagccaa gagcaggatt ctaacggtat ggttaaatca attgtgtctc agacaccggg
    15781 ggccatttct tacttatcct ttgcctatgt ggattcgtct gtaaaatcat tacgattgaa
    15841 tggctttaag gccaatgcca aaaatgtagc aaccaatgat tggcccatct ggtcctatga
    15901 gcatatgtat accaaaggca agccagacgg cttaaccaag gaatttttgg attatgtgct
    15961 atcagatgag gtccaaaaaa ccattgtgac acatatgggt tatattgcta tcactgatat
    16021 gaaggtcgtc aaatcctatg atggaaaagt tacagataaa taatggggga attatgaaaa
    16081 atcaggaatt agctaagcaa ttagcctcac catcaaaaaa ttcacgactt gaagcatttg
    16141 gtcgtacgat tacctttttt tgcctcgcct taattgtttt tatcgttgca atgattttaa
    16201 tttttgtagc tcaaaagggc ttgtctacct tttttgtaaa caaggttaat ctttttgatt
    16261 tcctatttgg tacagagtgg cagcctagcg ttaaaaatgc tgccggtgtt ccttatcttg
    16321 gagctcttcc gatgattgct ggatcgtttt tagtcacgat tttatcagcc ttggtggcaa
    16381 caccatttgc cattggggca gcagtattta tgactgaaat ttcacccaag tacggggcaa
    16441 agctattaca gccagcagtt gaattgcttg taggtatccc gtcagttgtt tatggcttta
    16501 ttggcttgca ggttgttgtt ccttttattc gttctatttt tggtggaaca ggctttggta
    16561 tcctatcagg ggtctgtgtc ttgtttgtca tgattttacc gacggttacc tttatgacaa
    16621 cagatagtct gcgcgctgtt cctcgtcatt atcgtgaagc ttctatggct atgggggcta
    16681 cacgttggca aaccatttgg cgagtggttt taaatgcagc tcgtcctggt atttttactg
    16741 ctgttatttt tggtatggct agagcctttg gtgaagcttt agctattcaa atggttgtgg
    16801 gaaattcagc agtcatgccg acttcactaa ccactccagc ggctacattg acctctgtat
    16861 tgactatggg aattggtaat acagtcatgg gaactgttca aaataatgtg ctatggtcat
    16921 tagcccttgt cttattgctg atgagtctag cttttaattc ccttgtcaaa ttaattacga
    16981 aagagagaaa gagaaattat gaacgctaaa aaggttgata aagtagcaac tggtagcttg
    17041 tatactattg ctggaattat tgtagctatt ttagcttccc taattctgtt tattcttgtg
    17101 cgtggcctac ctcacatcag ctggtcgttt ttaacaggga aatcatcgtc ctatgaagct
    17161 ggtggaggta ttgggattca gctttataat tcatttttct tgctggtagt aaccttgatt
    17221 atttccattc ccctatcaac aggtgctggc atttatttgg ccgaatacgc taaaaaagga
    17281 cctgtgacaa attttatcag aacctgtatt gaaatcctat cctcattgcc atctgttgtg
    17341 gttggattgt ttggctacct tatttttgtt gtacagtttg agtatggctt ttctatcata
    17401 tcaggtgccc ttgctttgac ggtatttaat cttccgcaaa tgacaagaaa cgttgaggac
    17461 agcttgctgc acgtgcacca cacgcaaaga gaggcagggc tagcccttgg gctttcacgc
    17521 tgggaaacgg tttttcatgt ggttattcca gaggccttgc caagtattgt gacaggtatt
    17581 gttttggctt caggtcgtat ctttggtgaa gcagctgctc ttatctatac tgcgggtcag
    17641 tctgccccag cgcttgattg gtcaaattgg aaccctttga gcgtgacaag ccctatttca
    17701 attttccgtc aatctgaaac cctagctgtt catatttgga aggtcaatag tgaagggaca
    17761 atccctgatg caacacttgt ttctgctggt agtgcagcgg tgttgttgat ttttatcctt
    17821 attttcaatc tatcagctcg ctttattggc aagcgtattc atgctaagat gacagcagca
    17881 aaataagaca ttggagagat tcatgacaga atataattgg aacgaacgtc atatcattac
    17941 atttccagaa gaaaccattg ccctagctac taaggatttg catgtttatt atggcagcaa
    18001 ggaggcaatc aaggggattg atatgcaatt cgaaaaaaat aaaattacag ccctaattgg
    18061 accctcaggc tgtggcaagt caacctatct gcgcagcctc aatcgcatga atgacaccat
    18121 tgatattgct agagtaacag gtgaaatttt gtatcaaggc attgatgtca atcgaaagga
    18181 catgaatgtg tatgaaatcc gtaagcacct aggaatggtc tttcaaaggc caaacccatt
    18241 tgccaagtct atttataaaa acatcacctt tgctcatgaa agagcaggag tgagagataa
    18301 aagggtttta gatgagattg tcgaaacctc cctcaagcag gctgcactat gggatcaggt
    18361 caaggacgat cttcataaat cagcctttac cctctcagga ggtcagcagc agcgcttgtg
    18421 tattgctagg gctatttcgg ttaagccgga tattttgttg atggacgaac cagcttcagc
    18481 ccttgatcct attgcaacca tgcagctaga agaaaccatg tttgagttga agaaggatta
    18541 caccattatt atcgttactc ataacatgca gcaggccgct agagcaagtg attacactgc
    18601 cttcttctat ttaggtgact taattgaata cgataaaacg cgtaacattt tccaaaacgc
    18661 tacctgtcag tccacaaatg attacgtctc aggacacttt ggttagaaag aaggatatga
    18721 tggcagaacc tattttacag atcagagatc tttctgttta ctataataaa aagaaaacct
    18781 taaaggacgt gtccttagat ttttacccaa atgaaatcac agcactcatt ggcccctcag
    18841 ggtctgggaa atcaacactt ttgcgttcca ttaatcgcat gaatgacctg aatccagagg
    18901 taaccattac ggggtcaatc gtttataatg gacataacat ttacagccca agaacggaca
    18961 ctgttgattt gcgaaaagaa attggtatgg tctttcagca gcccaatccc tttccaatgt
    19021 ctatctatga aaacgttgtc tatggcttgc gcctaaaggg cattagagat aaggctgttt
    19081 tagatcacgc tgttgaatcc tctctcaaag gagcctccat ctggagtgag gtcaaggata
    19141 ggcttcatga ttcagctgtt ggactatcag gaggtcaaca gcagcgtgtc tgcatagcaa
    19201 gggtccttgc aaccagccct aaaatcattt tgttagatga gccaacatcg gctttagatc
    19261 ccatttcagc cggcaaaatc gaagagaccc tgttctcact aaaaaaggat tatacgatgg
    19321 ttatcgttac ccgctccatg cagcaggcct cgcgcttgtc agaccgaaca ggatttttct
    19381 tagagggaga ccttcttgag tttggtccta ctaaggcaat gtttatgaac cctaagagga
    19441 aggaaacaga agattatatt tcgggtaaat ttggctaagg gatcttgttt gtagtctagg
    19501 tatcctctct gtttaggata ataaatgaat caatagaaag aaaaaatgat gttaagaact
    19561 aaatttgaag aagaattaga caagctacac aatcagtttt attctatggg aacagaagtc
    19621 ttgtctcaaa tcaataaaac cgttcgtgcc tttgtcagtc atgaccgcga attggctaaa
    19681 gaggtgattg aggaagacga taccatcaat gaatttgaaa caaaattaga aaaaaagtct
    19741 cttgaaatta tcgccttgca gcagcctgtt tcaaacgatt tgcgaacagt tattactgtt
    19801 ttgaaggcct caagtgatat tgagcgtatg ggagatcacg ctgcctctat cgctaaagca
    19861 accattcgca tgaaaggaga agagcgtatc ccgattgttg aggagcatat caacttgatg
    19921 gggaaggcag tcaagcagat ggttgaagag gcgctaaatg cttatattaa tgcagatgat
    19981 gctaaggcct atgagattgc tgcttcagac gaaatcattg ataattattt ccgcgaaatc
    20041 caatctctag ctgtcgaaga aattcgcaag acaccagatg ccgtctttgc tggcaaggaa
    20101 tacttccagg ttctcatgta tttagagcgt atcggtgact atgctcgtaa tatttgtgaa
    20161 tggattgtct atttaaaaac tggaaaaatt attgaattat aagaaagtat ggtataatgg
    20221 gggctgggtg aacttctcag ttcctcgttt tattatagcg attaaaaggt tttagaggct
    20281 ggagcttcag ctgagctgac tatcagctgt caagcttcta gacaaaatga aagataacaa
    20341 taagcgaagt cgtctaaggg actagacggc aggattgatt atattaagaa tgtgaccttg
    20401 tcccatcact aatttaatga catattaagg agttgtatga aaaaagtaga acatcttatt
    20461 gaaaagttta ttcctgaaaa ttataatatt ttcttagaca ttaatcgcag cacaaaaacc
    20521 ttcacaggta atgttgcaat caatggtgaa gcattagata atcaagtgtc gtttcaccaa
    20581 aaggacttgg caatcaatgc cattttactt gacaatgaag ctgttagcta ccatgttgac
    20641 gatgacaatg agcttgtgcg tgttgagctg ccagagactg gtatgatgac gcttgtcatt
    20701 gaattttcag gtaatattac tgacaatatg actggtattt acccgtccta ttacacaaaa
    20761 gatggtgaaa aacaggaggt tatttcaacg cagtttgaaa gccattttgc gcgtgaggcc
    20821 tttccatgta ttgacgagcc tgaagcaaag gctacctttg acttaagctt gacatttgac
    20881 caagcagagg gcgagattgc tctatcaaat atgcctgagg tcaatgctga gcgccgcaag
    20941 gagacaggtc tttggacctt tgagacaact cctagaatgt cttcttatct gctggccttt
    21001 gccttaggag acttgcatgg caaaacaaca aaaagtaaaa acgggacaac agttggtgtt
    21061 tatgcaacca aggctcaccc actgacctcg ctagattttt cattggatat tgctgtacgt
    21121 gtcattgatt tttacgaaga ctactttggg gttcgctatc ctattccgca atctctaaat
    21181 attgctcttc ctgatttttc atctggagcg atggaaaact ggggcttgat tacctatcgt
    21241 gaaatttacc tgttggttga tggcaattca acagcccgca gcagacaaaa tgttgctctt
    21301 gttgtggcac acgagattgc ccatcaatgg tttggtaatc ttgtaaccat gaaatggtgg
    21361 gacgatcttt ggctaaatga aagctttgcc aatatgatgg aatatgtagc catcaatgct
    21421 attgagtcgt catggcgtat ttttgaggat ttccaaacaa caggtgtgcc gctggctctt
    21481 aagcgtgatg caacagacgg tgttcaatca gtccatgttg ctgttaatca cccagatgag
    21541 attaataccc tgtttgatcc agctattgtc tatgccaagg gaagccgctt aatgcatatg
    21601 cttcgccgct ggattggcga taaagatttt gcggtaggtc tgcgccttta ctttgaaaag
    21661 catcaatacc gtaatactgt aggacgtgat ttgtggcagg ctctttcaga agcttctggt
    21721 aaagatgttg ctgcgtttat ggacgcatgg ctagagcagc caggctatcc tgtcttaacg
    21781 gccagggttg ataatgatca gttgattctt agccaaaagc agttctttat tggtgaagca
    21841 agtgatcaaa agagattatg gccaattcca ttaaatgcaa actggaaagg tcttcctgac
    21901 gtactgacag aggagtccat cgttatttca ggctttagtc aattagccgc ccaaaataaa
    21961 ggagcgcttc gctttaatac agaaaataca gcgcattaca ttacagatta tcagggacag
    22021 ctcttttata gcttagttga tgatttgaag catcttgaca acacttctgc ccttcaagtg
    22081 attcaggagc gccgcttgct ggctgatagc ggtctgattt cttatgcaga gctggttgat
    22141 ttgatcgctc agctggacga caaaaaatcc tatatggttg ctgcagctgt tcagcaggtt
    22201 attagaggct tagagcagtt tattgatgaa ggaacctcag tagagcagtc ctttaatcga
    22261 ttgatttctt ctattttcca agaggacttc agtcagcttg gatttgaaaa gagggcaaat
    22321 gaatctgatg aagatgagat ggtccgtcaa attgctttac atcacctgtt ggtcggaggc
    22381 aatcgtgatg tgatcaagca ggccaagact atctttgaag cttatgcaaa tcgtatcgaa
    22441 gccattccag cagccattcg ccgctcggta ttggtgagtc agatcaagta ttttgaaaca
    22501 gctgacttgg ttgatgctta ttttgatgtt tatgttgcaa ccaaggacaa caatcttcga
    22561 gctgatttga gcgccgcctt agcaacaaca gctaatccat caactcttaa gcgcattcag
    22621 tacagcttaa aggataagga tattattaag ccacaggact tagcagcttg gtacagcttt
    22681 ttgcttgatc aggcctctgc acaagaaagc atttggcgtt gggctagaga aaactggaaa
    22741 tggattaagg cttcattggg tggtgatatg agctttgaca agtttattat ttacccggct
    22801 aaccatttta aaacagcaga gcgtttagct gaatataagg ccttttttga gccacagctt
    22861 gatgatatgg cgattagtcg caatatttcg atggggataa aagaaatttc agctcgagtt
    22921 accctcattg atagtgaaaa agaagctatc gctaatgctt taagtcagta ttaatgatat
    22981 cacaaaggag ctggggacca tcctcaactc ctttattggt gtcaaagcta ctatctttaa
    23041 gtaacattta gatcaaaggg taattgctgt cgcttagtgg cactgcctgt cagcttttgg
    23101 caaatgagga ggcttcaatc ataagcagtg gttaatctta gcaccgtaaa ttgctagttg
    23161 atcagagtca gagcttagga cggataggtc atagagacaa ttctttgtct gtcagtttta
    23221 tgacttaagt aggtatccag attaactgta tgcttatgac ctgtcatgag caatatttta
    23281 gcaaagctta agctttttgt gttatcgttg gactagagaa ttcatttagt aaggtaatct
    23341 ctaaagactg cttgagcgag gctgttagtc tttagagaat tgaggtatca taatgataaa
    23401 actattatta gtagaagacg atttaagctt gtcaaattct atctttgatt ttttagatga
    23461 ctttgctgat gtgacgcagg tttttgatgg tgacgaagga ctctatgagg cagaaagcgg
    23521 tatttatgat ttgattctgt tagatttgat gctgcctgaa aaggatggct ttcaagtgtt
    23581 aaaagcctta cgtgaaaaag acatcaaaat tcccgtcttg atcatgactg ccaaagaaag
    23641 catcgatgac aaggggcatg gctttgagct tggtgctgat gactatttaa ctaagccctt
    23701 ttacctagaa gaattaaaaa tgcggattca ggccttgctt aagcgcgtag gaaagtttaa
    23761 tgataagagc cttaaatttg gcaacctgac tgtagatact acccgtaaag aggtacaggt
    23821 caatgggcag gtcatagagc tattaggtaa ggagcttgat ttactagtct atattcttca
    23881 aaatcaaaat gttattttgc caaagtcaca aatttttgat cgtatctggg gctttgatag
    23941 tgataccact atctctgttg tagaggtcta tgtctctaaa atccgtaaga agcttaaggg
    24001 gacagacttt gttaatcatc ttcaaacctt gagaagtgta ggatatatct taaaagctaa
    24061 tgaataaact aaaaaaagaa ttattgtccg ataattatac acattttttt catttctttg
    24121 ctatttttac aggcattttt gttgtcatga ctatcattat tttgcaaatc atgaggttta
    24181 gtgtctattc cacagtagac agcagtctca tttcggtcgg tcaaaatgcc agcaactatg
    24241 ccaataggac catggcgaga atatcttcct tttattttga tgcagaaaat aaccttattc
    24301 aggctcttcc tgaactggaa gcgtcaaaat cacttggctc ctccaccact aatatggata
    24361 ttattttatt tagtgctaat gggacgatat tgaactcctt tgacgctttc tctaattacc
    24421 aaagctttcg tttagacaaa agccagctca ataacattgt cacaacacag ctgatgaatt
    24481 tttatgggca aaaggagaaa taccataccc taactgttaa ggttcacatt aaaaactatc
    24541 cagcagtggc ttatatgatg gcagtggtta atgttcagca gctggatact gctaatgagc
    24601 gctatgaaca gattattatc atggttatga ttgtcttttg gttaatttcg attttggcca
    24661 gtatttattt ggctaagtgg agcagaaagc caattatgga gagctatgcc aagcaaaaaa
    24721 tgtttgtaga aaatgccagt catgagctta ggactccttt agcggtgctg caaaatcgtt
    24781 tggaatcgct gtttagaaag cctaacgaaa ccattttaga caatagcgag catattgcgt
    24841 caagcctaga tgaggttcgt aatatgagaa tattaacaac taatctgtta aatttagcca
    24901 gacgtgatga tgggatcaag ccgcagctag ttgatgttga tgcagccttt tttgatactg
    24961 tttttgaaaa ttatcaatta gttgcagaag agtcaggcaa gcagtttatc tcagctaatc
    25021 agatcaatag gcccttaaag acggataagg ctttgctcaa gcagctgatg accattttgt
    25081 ttgataatgc gatcaaatac actgatcata acggtgtggt tgaggtcaag gttagaacga
    25141 ccgataagca tttattgatt tctgttattg ataatggccc agggatcaag gatgatgata
    25201 agaaaaagat ttttgatcgc ttttaccgag tggataaggc aaggacacgc caaaaaggag
    25261 ggtttggact cggattggcc ttagcgcagc agatcgttac ctcattaaaa ggaacgatta
    25321 ccgtcagtga taataagcct accggcgcca tctttgaagt aaaattatag cactgagttc
    25381 ttgctagccc ataatcagta tgaaaataac agtcactaga tcaagaagtc tagtgacttt
    25441 ttttattgtc ttctttttgc tgttgaccaa gcagttgaca
//
LOCUS       DARYSY010000029        24653 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYSY010000029 DARYSY010000000
VERSION     DARYSY010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24653
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1267
                     /locus_tag="TVR04_001116"
     CDS             <1..1267
                     /locus_tag="TVR04_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1269814.1"
                     /translation="DKREIVGVSKDKVDKVIKEFTTAINNSQKMYPPLYLLPEVFDID
                     EKKVIYIRVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYP
                     NLDIDFLDASVIDKAKKMAVSRNKNHVWENMSNEELLRSANLILTDPETKREGITLAA
                     ILLFGKDNSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLND
                     LFVLDGIVNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDQRITVENSNLAHGMGA
                     LDLQKFEPFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGENPLFEEGDIFRTI
                     IPLKKIATQKVGGGNVPRNVPQDVSRMSLEEIENIIKDMIKGDNRVSRKDIAMVLGVS
                     EKTITRYIKDIPNIKYVGKGKNGHWELNE"
     gene            1353..8684
                     /locus_tag="TVR04_001117"
     CDS             1353..8684
                     /locus_tag="TVR04_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003034181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1269815.1"
                     /translation="MRINDFHNILELVKQDVLRSEAEYLKFLKVVGNNQRYDFRSQLS
                     IYDRNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDIGQTVSRNR
                     DVNEVNLWRFDKEAHRDVLKEMIVSEGYEESESILENIFSLSRLYGDEKIDSLMNELR
                     IADEDRISFTKFVRDSVSYAVASRFKVDYPVDNELLKENFAKLDRISLMSLGETVSDI
                     SGKIIDETIQKSKEMELQKEVLRGKEAGYNRIKEELEEVEENVLRRDDQKRNESGRVL
                     RNGEYGRDNRENQGEYAKQLGGTDGLHKGVSESDLRSDEAGLPFTERGAEPLRDVGRS
                     IQGEEANRTPDRYSETGNRIYENGEGEIDGSLEDRGREQSTVWGDDFGSEGNDNQGSS
                     GNLKDNTNVELKEAEKASFSLPENFYGQMRLTIPLNQKDIDTILINGGNHDGGRLPLI
                     AEFSKGKSNGELGEYLKDTFKGGNGFYIDEREVSSWYSDKGIHLSYGTSAREDDTQIL
                     SWSNAASRINELLETGEFATNVELFEALDYERDRISESLWYLYHDLSEEGKAQGYFDF
                     IERGGGFPEETKRLSEALKNPEYLKETIKEYSRFLEGYKENRNVLRFHYHKVDSLYQR
                     LQELKLSRKEYSTNLTELPKVKSFITEDEVKATISRGSGIDKGKERITKFFKENHTLQ
                     EKAHFLKDEYGIGGRSHAVSGAMGSDEWHDAKGLKLQKKDCSNVFLTWSSVAKHIDEL
                     LSKNLYEEKKIESKAEIEKAKAPQYYSKDDPENLMTDEMLERVPELYSQEDVALADKE
                     VHAAYIIPFRLNWTWYMTEYDRESGDAFGLVLGFEPEWGYFNLEELKELNAQRLILED
                     FPKTFRELKDTELKKQMDEQELQAIFNGELSFEDKEELEISEEVEERVAVTPVQGTLF
                     DYLKEREEVELNEEKESRADESEIKEGDTVYFNHEEYTVREISKNKITGRNDLWLDPV
                     RSGNHQIPIVAFTDNEDLLRQISPERPVFIVGDEIKYKDKDYTITRFDDMGNNLKTVT
                     VKDNTEYLGGMITGSDVIPYRLENDLERVFENLTYKKPETITKESEIKKIEAHNFKIT
                     EETLPEKLSPSERLNNNLEAISMLNRVENGQRELDSTAQEVLARYVGWGGLADVFDEE
                     KGGQWKEARSFLKENLSQAEYEAARESTLTSFYTPKTVIDGVYKTLSDMGFKQGNILE
                     PSMGIGNFIGNLPDEMRRSKFYGVELDSISGRIGKLLYPESDIQIKGLEETSFSNNFF
                     DAVIGNVPFGEYKVNDREYNRNNFLIHDYFFAKSIDKVRNGGVIAFITSSGTMDKKDE
                     SVRRYLAARAEFLGAIRLPNDTFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHLAEDE
                     NGLVYNKYFVDHPEMVLGSMEEVSGRFGKTLTCEPIAYLGTELNMASLKERIEIAGER
                     ISKDAKYEEIELLDDEITSIPATDDVKNFSYTIIDDEVYFRENSIFVKKEVTDKNKEK
                     IKDYLELNEALKDVIYKQKEDFSDDEVKKSQEKLNEIYDSFSKKHGYVNNLSNTRALK
                     EDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKVIDHVDTSLEALVLSVSEKGYV
                     DFEYMGSLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSY
                     KYGYVTKDEYLSGNIRDKIAIVDSYLAKLRQTERELPHLGYAEDGKEKELISYEMNRL
                     EYQKAELTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGWARWDIKVKFSN
                     LTSEWNVEGKSKDRGNDLAEMTYGTSRVNAYKLIEDALNLKETKVFDQIVNPDGSKTS
                     VLNKKETMLAGQKQELLKEEFKNWIFSDQERRNRLVKLYNERFNSIRNREYDGSKLSF
                     EGMNTKIELRPHQKNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLF
                     VVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGRIATGEYDAVVIGHTQF
                     EKIPMSKEYQEKHIQDQIDEIINYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDD
                     FKKDDVITFEELGVDKLIVDEAHNYKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYM
                     DEMTNGKGIVFATGTPVSNSMTELYTMQRYLQYDDLKKNGLEHFDSWASTFGETQSAF
                     ELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEAHYEVIKTLPSE
                     EQKEILKSLSERADDVRNRVVEPDEDNMLKITNDGKKLALDQRLINPLLPDNPDSKVN
                     VCVKNVFAIWDKTKEDRSTQLLFSDMSTPKGDGEFNIYDDIRDKLVAMGIPKEEIAFI
                     HEANSDKQKDELFAKVRKGDVRILLGSTQKMGAGTNVQNKLIALHDLDVPWRPADVGR
                     ILRTFKIKKNVEVTDNGKDNF"
     gene            8665..9039
                     /locus_tag="TVR04_001118"
     CDS             8665..9039
                     /locus_tag="TVR04_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1269816.1"
                     /translation="MAKTIFEEMGGKYERQGDYLIPCLTVPAEEEQPIGIWGQRHLDY
                     LKHHCKVTYTNLLTSGRLNAYLADIDRQAQERFERLIEGMKQAQGITEQLKAENALEW
                     TGCLNNIRACAREIVEKEIIFA"
     gene            9406..11325
                     /gene="tet(O)"
                     /locus_tag="TVR04_001119"
     CDS             9406..11325
                     /gene="tet(O)"
                     /locus_tag="TVR04_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HEL1269817.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRKFIENPLPMLQTTIAVKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     NVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQVKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPAIGKFICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            11377..11550
                     /locus_tag="TVR04_001120"
     CDS             11377..11550
                     /locus_tag="TVR04_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002779755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEL1269818.1"
                     /translation="MMKCEWILCPVCGSKTRNKIRKDTVLENYPLYCPKCRQESLIKV
                     DNLKITVIKEPDA"
     gene            12040..12549
                     /locus_tag="TVR04_001121"
     CDS             12040..12549
                     /locus_tag="TVR04_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1269819.1"
                     /translation="MKYAPRKVYIKESGGYVELSYTDFCRRRQADKGYMDKLFIPVQG
                     CLLEVVREQYADFYRDRERWRYLQKLDARNSLLSLDGFTDSEGNPLDFIADEAADIAE
                     TVVNAVMVDRLKAALPLLSDSEQELIQAIFFDGLSEREVGARLGITQSVVNKRKARIL
                     RKLRKIIEN"
     gene            12644..13069
                     /locus_tag="TVR04_001122"
     CDS             12644..13069
                     /locus_tag="TVR04_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1269820.1"
                     /translation="MAYNHGREDRKWRIWKEAEEKLLRECGVDEVTIEQIRIADRADF
                     NSNRRFYRWTNDVAEYLEDMADRERQAEVNTVAELLDEIESENLYQVLVTVDGRTLKI
                     VLLKMQGYSTKEIAPLVHLTTGAIYARLDHLRKKLRKIL"
     gene            13153..13626
                     /locus_tag="TVR04_001123"
     CDS             13153..13626
                     /locus_tag="TVR04_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1269821.1"
                     /translation="MAYKAKAYTLREESTESGIRYFISFKDGQGEHHELEVSEQLFFE
                     FRQMERRNRNLLQWDERHREFSEVWDETLNRRALKLPKSIEEQMIEAERAELLCKAVD
                     RLPEIQRRRFLLYYEYEFNFYQIAAMEHCTASAIQKSVAVAKKKVKAEMRKYLQP"
     gene            13780..14811
                     /locus_tag="TVR04_001124"
     CDS             13780..14811
                     /locus_tag="TVR04_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1269822.1"
                     /translation="MQKLQTVNAETLLYEPLEKPSFVVDSLIPTGLSLFCGSQKIGKS
                     WLMLKLCLCVSQGIPLWDMTTMEGDVLYLCLEDTFCRIQDRLFRLTDEASGRLHFAVA
                     SCKLSDGLIVQLEDYLKDYPDSRLIVIDTLQKVRTASKDNAYASDYGDISLIKDFADR
                     HSLAVIVVHHIRKQNDSDVFNKVSGTTGLTGSADATFVLEKEKRASDTAKLYVTGRDT
                     PYQEYTLRFRDCSWELVERKTQEQLAKETIPDVLFRLVDFMRDKEEWAGTATELLAAM
                     GETETIPTVITKWLNEYHTTFLSENRICYQYSRRKDGRQIALARRAGDSGDGGDSDIG
                     IPPVTVIDA"
     gene            15330..16295
                     /locus_tag="TVR04_001125"
     CDS             15330..16295
                     /locus_tag="TVR04_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEL1269823.1"
                     /translation="MPYAILRFQKRKAGGVAACERHNERKKEAYKSNPDIDMERSKNN
                     YHLVAPPKYTYKKEINRKVAEAGCRTRKDSVMMVETLITASPEFMNQLPPEEQKAYFT
                     MALDFISERVGEQNILSAVVHMDERTPHMHLCFVPITPDNKLSAKTILGNQKSLSEWQ
                     TAYHERMSSRWNQLERGQSSMETKRKHVPTWLYKLGGRLDKQYGEIVSALSDINAFNA
                     GKKRDKALELVAAWLPEVEKFSKEIGRQQAYIDSLKEQIGQEADYAGRMRDEKYEQEL
                     KVQKANQRIFELQRTNEQMGRLLSKIPPEVLEELQRTGRNKSRER"
     gene            16303..17157
                     /locus_tag="TVR04_001126"
     CDS             16303..17157
                     /locus_tag="TVR04_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1269824.1"
                     /translation="MKKQDFKVLKTKDLYPFPDNPFHVVEDETLSELAESIKEFGIVT
                     PIITRPKEDGNGYEVIAGQRRVRASELAGINTVPAFVLPLDRDRAIITLVDSNLQREN
                     ILPSERAFAYRMKSEAMKRQGFRTDLTSSQVVTKLRTDDKVAQGFGVGRMTVQRFIRL
                     TELIPPILQMVDEGKIALTPAVELSFLKKDEQENLFATMESEEATPSLSQAQRMKSMS
                     QSGQLDMDMIFSIMTEEKGNQKETLKINTSKLKKYFPKDTTPKQMEETIIRLLERELQ
                     RKRSRDSR"
     gene            17234..17464
                     /locus_tag="TVR04_001127"
     CDS             17234..17464
                     /locus_tag="TVR04_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269825.1"
                     /translation="MKEIQYEIVKEIAVLSASDSGYTKEINLISWNGREPKYDIRSFS
                     PNREKCGKGITLNADEAAALLEALQKEVNSGD"
     gene            17535..17726
                     /locus_tag="TVR04_001128"
     CDS             17535..17726
                     /locus_tag="TVR04_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HEL1269826.1"
                     /translation="MGEDRKTTGRRKRIVPKGQVQMIISREYIGTQTVAEAFVPIISE
                     DIRKKIAEGDTFDNEGLSA"
     gene            17780..19666
                     /locus_tag="TVR04_001129"
     CDS             17780..19666
                     /locus_tag="TVR04_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1269827.1"
                     /translation="MAGIRTENKIYEVGIYCRLSKDDGTDNESASIATQKSILTDYVK
                     RQGWHLAKTYVDDGYSGTNFQRPSFQNMIKDIENGLINCVITKDLSRLGRNYLDCGLY
                     LEVFFPEHNVRYIAVNDGVDTLNKSAMDITPFRNILNEMYSADVSVKIKSAYRARFQQ
                     GKFMGTTAPYGYVKDPADHNHLLIDDKVAHVVREIFDLALAGNGIAKIRKHINKQHIL
                     RPAAYAVEQGATGYERYFEDNEENRYIWSENSVRGILRSPIYAGNLAGYKRIAANMKS
                     KKRPSKLPEEWEVIPDTHEGIVTQEEFDTVQQLMTSRRREQNAGGFENIFSGVIKCAD
                     CGYAMRAASANRRKRPDIIDCVQYTCNNYGRYGNVMCTAHSIEARDLFNAVLADINRF
                     ADMAVNDEKAVRAIERRLTETDQSRAKSLEKEKKKLNKRLAELDRLFSSLYEDKVMER
                     ITERNFEMMSGKYQKEQLEIEARLKEVTETLNDSYEKSQGVRDFLSLIRNYQGLKELD
                     ATIINALIDKILVSEREKLADGTVRQEIKIYYKFIGFVGELHITPTKRWTALKPKNCT
                     VCGVEYVPSSGISKYCPACAKRIQREKSNESKRRSRERNRRACIELSAKNDRLTLSRE
                     QEEL"
     gene            19636..21129
                     /locus_tag="TVR04_001130"
                     /pseudo
     CDS             19636..21129
                     /locus_tag="TVR04_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019107295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            21170..21829
                     /locus_tag="TVR04_001131"
     CDS             21170..21829
                     /locus_tag="TVR04_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1269828.1"
                     /translation="MDYKTMRDRIEDMVNDNHKDFVKAIISMEKGINDESALDKLYDA
                     YMENDTVNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVIEREN
                     KNGEAFKVANFSVVSKDNEGNKVYHNCSAYGDKGDIPKDFKQGDFVKLFGQIRTSIDD
                     NGGEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQAEDKEKPKEKKEANREAE
                     R"
     gene            complement(21901..23232)
                     /locus_tag="TVR04_001132"
     CDS             complement(21901..23232)
                     /locus_tag="TVR04_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1269829.1"
                     /translation="MAITKIHPIKSTLNLAIEYIVNGDKTDEQILVSTHKCHESTAHT
                     QFLRTRNDAGTKGTVLARHLIQSFLPGETTPKMAHQIGIELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGRCYQSNKKSYHQIRYQSDKLCKENNLSVIDEFYESYKKK
                     YKTNGKSWYENEQVKRGTSWKSRLQFDIDRMINQSNNWDEFLKKMADLGYEIKYGKHI
                     AFKPKDKPRFTRAKTIGEDYTEERLKERIAEIVSIKNSTVKKRIGNVIDMNTNTKVKE
                     SKGYEYWATKHNLNTMAESIIFLREQGIKSVKQLDEYIQKSADERQNLQDKIKVIDKE
                     MQELSATMEQVHTVKKYRQYYKEYKASPSDKAFFEEYKAQITLYENALSELKKSYSKL
                     PNSKGILDRLDKLQEKKNTLMQEYSSSKSIMDELYKIRKNYGIYMGKEMER"
     gene            complement(23238..23588)
                     /gene="mobC"
                     /locus_tag="TVR04_001133"
     CDS             complement(23238..23588)
                     /gene="mobC"
                     /locus_tag="TVR04_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1269830.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLAKCRNMSHFIRKCVLE
                     KEIYQVDLEPFRNLQGLLSNATNNINQIAKRVNSTGIIYKEDINDMKKQIEHFSKELW
                     QIHSLLLNRTSGGD"
     gene            23891..>24653
                     /locus_tag="TVR04_001134"
     CDS             23891..>24653
                     /locus_tag="TVR04_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HEL1269831.1"
                     /translation="MKDNRLFRILYYILEKGKVTASELADKFEVSVRTIYRDIDSISS
                     AGIPIYALQGKGGGIEIAEDFVLSKSLLSENEKQQIMSALQGLENTTIQHENELLTKL
                     SALFKIKNTSWIEVDFNNWQNNKMYEKTFNDIKSAILSKNIVSFTYFSSNEKETSRRV
                     KPVRLLFKSQDWYLYALCLLRNDFRYFKLSRIKNLEIHTEKFDDNFEDVILKKETPHE
                     NTVNIKVKFDRKVAFRVYDELNGEITEDNDGNLYTE"
BASE COUNT         8219 a         4243 c         5858 g         6333 t
ORIGIN      
        1 tgataaaaga gagattgttg gtgttagtaa agacaaagtt gataaagtga ttaaggaatt
       61 tactacggca atcaacaatt cgcaaaagat gtatccacca ctttatttgc tacctgaagt
      121 ctttgatata gatgagaaaa aagtaattta catcagagtg ccggaaggct atcaggtgtg
      181 cagacataac ggcagaattt gggacaggtc ttatgaagga gacatcaata tcacagatca
      241 ttctgaactt gtatataagt tatatgcaag aaaacaagga agctattttg taaataaagt
      301 atatccgaat cttgatattg attttcttga tgcttctgtc attgataagg ctaagaaaat
      361 ggctgtttcc cgaaataaaa atcatgtttg ggagaatatg agtaatgagg agcttcttag
      421 aagtgcaaat ctcattctga cagatccgga aacaaagcgt gaaggaatta cattagctgc
      481 tattttgtta tttggaaaag acaactctat catgtccgtt cttccacagc ataaaactga
      541 tgcgatattt agagttgaaa acaaggatag atatgacgat agagatgttg tcataacaaa
      601 tctgattgat agctatgaca gacttataga atttggacag aagcatttga atgatttatt
      661 tgtcttggac ggaattgtaa atgtcaacgc aagagatagg atactcagag aaatagtttc
      721 caatacattg gctcatagag attattcaag tggttttcct gcaaagatga ttattgacga
      781 tcagaggatt acggttgaaa acagcaactt ggctcatgga atgggagctt tagatttaca
      841 gaagtttgag ccatttccca agaatcctgc tatatcaaag gtgtttagag aaataggtct
      901 tgcggatgaa cttggttcag gaatgcgaaa tacctacaag tacacacagc tttattcagg
      961 agaaaacccg ctatttgagg agggggatat attcaggacg attattcctc taaagaagat
     1021 agcgacacaa aaagttggtg gagggaatgt ccctcgaaat gtccctcaag atgtctctcg
     1081 aatgtccctc gaagaaattg aaaacataat caaagatatg attaaagggg acaatagagt
     1141 gagccgtaaa gatatagcta tggtattagg agttagtgaa aaaaccatta caagatatat
     1201 aaaagacatt cctaatatta agtatgttgg taaagggaaa aatggtcatt gggaactgaa
     1261 tgaatagaat taagttgcaa tacacagaat ttaaaggtga ttagagtaaa atctaaccac
     1321 cttttttgtt tggaaaaaag aaggaggtaa aaatgcgaat aaatgatttt cataacattt
     1381 tggagcttgt aaaacaagat gttttgcgaa gtgaagcaga atatctaaag ttcctcaagg
     1441 ttgtcggaaa caatcagaga tatgacttta gaagtcagtt aagtatctat gatagaaatc
     1501 ctgaagcgac agcctgtgcc aagttcgact attggaggga acgatttaac cgtaccgtta
     1561 tgagaggtca aaagggtatc ccaattttgg aggactacgg cacatacaaa aaagtggact
     1621 atatctttga tataggtcag acggtttcaa gaaacaggga tgtcaatgaa gtaaatcttt
     1681 ggagatttga taaagaagct catagggatg tcttaaagga aatgatagta agtgaaggtt
     1741 atgaggaaag tgaaagcatc ttagaaaata tcttttcttt aagcagactt tatggtgatg
     1801 aaaagataga cagccttatg aatgagctta gaatagcaga tgaagataga atatctttta
     1861 ctaaatttgt gagggactca gtgagttatg cagtagcttc aaggtttaag gtagactatc
     1921 ctgtggataa tgagcttcta aaggaaaact ttgcaaagct tgatagaatt tcccttatga
     1981 gcttaggcga aaccgtatcg gatattagcg gaaagattat tgatgaaacc attcagaaaa
     2041 gcaaagaaat ggagcttcaa aaagaagttt taagaggaaa agaagcagga tataatagga
     2101 ttaaggaaga attagaggag gtagaagaaa atgtacttcg acgagatgat cagaaaagaa
     2161 atgaaagcgg gcgagttctc cgaaatggag agtacggacg agataataga gaaaatcagg
     2221 gagaatacgc taaacagctt ggaggaacag acggacttca taagggagta tccgaatccg
     2281 acctacgcag tgatgaggct ggattacctt tcacagagcg aggagcagag ccgcttcgag
     2341 atgttggtag atctatacaa ggagaagaag ctaataggac acctgataga tattcagaaa
     2401 caggcaatag aatttatgag aacggagaag gcgaaattga tggcagcttg gaagatagag
     2461 gacgagaaca atccacagta tggggcgatg atttcggctc tgaaggaaat gacaatcaag
     2521 gaagtagtgg aaatttaaaa gataatacta atgtagagct aaaagaagct gaaaaggctt
     2581 ctttttcttt gcccgaaaat ttttatggac agatgaggct tactattcct cttaatcaga
     2641 aagacataga cactatcctt attaacggag gaaaccatga tggtggtagg cttcctctta
     2701 tagcagagtt ttctaaagga aaaagtaatg gagaattggg agaatacctc aaagatacat
     2761 ttaaaggagg aaatggattt tacattgatg aaagagaggt atcttcctgg tattcggata
     2821 aaggcattca cttatcttac ggaacatctg caagagaaga tgatacgcaa attttaagct
     2881 ggagtaatgc agcaagcagg ataaatgagc ttttggaaac cggagagttt gccacaaatg
     2941 tggagctttt tgaagcctta gattacgaaa gggatagaat ttcagagtca ttatggtatc
     3001 tataccatga tttaagcgaa gaaggaaaag cacaaggtta ttttgacttt atagaaagag
     3061 gtggtggttt tccggaagaa acgaaaaggt tatctgaagc attaaaaaat cccgaatacc
     3121 taaaggaaac gatcaaagaa tacagcaggt ttttagaggg atacaaagaa aacagaaatg
     3181 tattaaggtt tcactatcac aaggtagaca gcctttatca gaggttacag gaactcaagc
     3241 tgtcacgaaa ggaatacagt accaatctga cagaacttcc caaagtgaag tcctttatta
     3301 cagaagatga agtcaaagct actatttcaa gaggaagcgg aatagataag ggaaaagagc
     3361 gaattacaaa atttttcaag gaaaatcata cgcttcaaga aaaagctcac ttcttaaaag
     3421 atgagtatgg catcggtggt agaagtcatg cagtatcagg tgcaatggga agtgatgaat
     3481 ggcacgatgc aaagggactt aaattgcaaa agaaagattg cagtaatgtg tttcttactt
     3541 ggtcaagtgt ggcaaagcat attgatgagc tgctttctaa aaatctgtat gaagaaaaga
     3601 aaatagaaag taaggcagag atagaaaaag caaaagcacc acaatattat tctaaagatg
     3661 atcctgaaaa tctaatgacc gatgaaatgc ttgaaagagt ccctgagctt tattcacagg
     3721 aggatgtagc attagcggat aaagaggttc atgcagcata tatcatacct tttcgtttaa
     3781 actggacttg gtatatgacg gaatatgaca gggaaagcgg tgatgccttt ggacttgtgt
     3841 taggatttga gcctgaatgg ggatatttca atcttgaaga attaaaggag ttaaatgccc
     3901 agaggctaat tttagaagat tttccaaaga cctttagaga acttaaagat acggaactta
     3961 aaaagcagat ggatgagcag gagcttcaag cgatatttaa cggagagctt agctttgaag
     4021 ataaagaaga acttgaaata tctgaagaag tagaagaaag agtagctgta acacctgttc
     4081 agggaacgct atttgattac ctcaaagaaa gagaagaagt agagcttaac gaagaaaagg
     4141 aaagccgtgc agatgaatct gaaattaaag agggagatac cgtctatttt aatcatgaag
     4201 aatacaccgt aagggagatt tctaaaaaca aaatcacagg aagaaatgat ttatggcttg
     4261 atccggtaag aagtggaaat catcaaatcc ctattgtagc ctttacagat aatgaagatt
     4321 tattaagaca aataagccct gaaagacctg tgtttatcgt tggagatgaa attaaataca
     4381 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     4441 cggttaagga caataccgaa tatcttggcg gtatgataac aggctccgat gtaattcctt
     4501 atcgtctgga aaacgatctt gagagagtat ttgaaaatct gacatataaa aagcctgaaa
     4561 ctattactaa agaaagtgaa ataaagaaaa ttgaggctca taacttcaag attacggaag
     4621 aaacattacc tgaaaagtta tctccaagtg aaaggctaaa taataacctt gaagcaattt
     4681 ccatgcttaa tagagtggag aatggacaaa gagaacttga cagtacagca caggaagttt
     4741 tagcaaggta tgtaggctgg ggaggacttg ctgatgtatt cgatgaagaa aaaggcggac
     4801 agtggaaaga agcgaggagt tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     4861 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     4921 agacactttc agatatggga ttcaagcagg gaaatatcct tgagccatca atgggcatcg
     4981 gaaactttat cggtaatctt cctgatgaaa tgcgtaggtc aaagttttat ggtgtagagc
     5041 ttgacagtat aagcggtcga atcggaaagc tgttatatcc tgaaagtgat atacagatta
     5101 aaggacttga agaaacttcc ttttccaata acttttttga tgcagttatc ggtaatgttc
     5161 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     5221 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     5281 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag aaggtatctt gcagcaagag
     5341 cagagttttt aggagctatc agacttccta atgacacctt taagggtgtt gccggcacag
     5401 aggtaacaag cgatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     5461 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgtagatc
     5521 atcctgagat ggtgcttgga agtatggagg aagtatcggg aagatttgga aaaactctaa
     5581 cttgtgaacc gatagcttat ttaggcacag agctaaatat ggcttcatta aaggagcgta
     5641 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     5701 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     5761 ttgatgatga ggtctatttc agggaaaatt ccatatttgt aaagaaagaa gtaacggata
     5821 aaaacaagga aaagattaaa gattatcttg aactgaacga agccttaaag gatgttattt
     5881 acaaacaaaa agaggatttt tcagatgatg aggtaaagaa atctcaggaa aaattaaatg
     5941 aaatctatga cagcttctct aaaaagcatg gatatgtcaa taacctttct aataccagag
     6001 ccttaaaaga agatagcaac tttcctttgg tatcatctat tgaaattctt gatgaagaag
     6061 aaaacttcaa agcaaagggc gatattttca gtaaaagaac aatcacaaag gctaaagtca
     6121 tagatcatgt tgatacttct ttagaagccc ttgttttatc ggtatctgaa aagggctatg
     6181 tggattttga atatatggga agtcttacag gaaaagacag accgactttg attgaggaac
     6241 ttaggggaga gatttatcta aatatcagag aggaacaaaa cttttacaga ccactgtctt
     6301 ttaacttgga agatggagat ttaccttttg cctgtgccaa tggtagcaat tcctataaat
     6361 acggttatgt aacaaaggat gaatacctaa gcggaaacat cagggacaag attgccatag
     6421 tagacagcta ccttgcaaag ctaagacaga cagaaaggga acttcctcat cttggctatg
     6481 cagaagatgg taaagaaaaa gagctgatca gctatgaaat gaatcgtttg gaatatcaaa
     6541 aagcagagct taccaaagtt ttaccaaagg agcttgaagc aagtgaaatc aatgtaaggc
     6601 ttggtgcgac atggataccg attaaggata ttgaaaagtt tatttttgaa acacttaaaa
     6661 caccgggttg ggcaagatgg gatataaagg ttaaattttc aaatttgaca agcgaatgga
     6721 atgtagaggg aaaaagcaaa gacagaggaa atgatcttgc tgaaatgact tatggtacaa
     6781 gtagagtaaa tgcctataag ctgattgaag atgcactgaa cttaaaagaa acaaaggtat
     6841 tcgaccagat tgtaaatccg gacggctcca aaacttctgt actaaataaa aaagaaacca
     6901 tgcttgcagg gcaaaagcag gagcttctaa aagaagaatt taaaaactgg atatttagcg
     6961 atcaggaaag aagaaacaga cttgtaaaac tgtataatga gcgttttaac tctatccgaa
     7021 atcgtgagta tgacggaagt aagctatctt ttgagggaat gaatacgaaa atagagctta
     7081 gacctcatca gaaaaatgct attgcaagaa gtttgtatgg tggaaatacg ctgcttgctc
     7141 atgtggtagg tagtggaaag acttttgaaa tggtggcttc cgcaatggaa tctaaaaggc
     7201 ttgggatgtg ttctaagtct ttatttgttg taccgaacca tctaacagga caaatcggca
     7261 gagagtttat gcagctctat ccgtcagcga atatcatggt ggcagataag aaagactttg
     7321 agccgaaaaa ccgtaagcgt ttcatcggta gaattgcgac gggagaatac gatgccgttg
     7381 ttatcgggca tacgcaattt gaaaaaattc cgatgagtaa ggaatatcag gaaaagcata
     7441 ttcaggacca gattgatgaa atcataaact atgttgagga atataagcat gatagaaatc
     7501 agaactttac ggtaaaacag cttgaaaaga caaagaaaaa acttgaaaca aggcttgaaa
     7561 aattaaatga tgattttaag aaagatgatg tcattacctt tgaagagctt ggcgtggata
     7621 aactgatagt tgacgaagct cataactaca aaaaccttta tctttataca aaaatgagaa
     7681 atgtagcagg tatcgggcag tctgaagcct ttaagtcttc cgatatgttt atgaagtgcc
     7741 gctatatgga cgagatgaca aacggaaaag gtatcgtatt cgctacagga acacctgtca
     7801 gtaactcgat gacggagctt tataccatgc agagatattt gcagtatgat gatttaaaga
     7861 aaaatggctt agaacatttc gactcctggg cttctacttt tggagaaacg cagtcagctt
     7921 ttgagctttc tcctgaggga accggatata gagtgaagac aagattttct aagttctata
     7981 atcttccgga gcttatgagt atgtttaagg aagtggcaga tattcaaaca gcggatatgc
     8041 tgaatcttcc aacacctgaa gcacattatg aggttatcaa aaccttgcca agtgaggaac
     8101 aaaaggaaat cctaaagagc ctgtctgaaa gagctgatga tgtcagaaac agagtggtag
     8161 agcctgatga agataatatg ctgaagatta ccaatgacgg caagaaactt gctcttgacc
     8221 aaagactgat caatcctctg ctacccgata atcctgacag caaggtcaat gtatgcgtaa
     8281 aaaatgtgtt tgccatttgg gataagacaa aagaagatag gtcaacacag cttctatttt
     8341 ccgatatgtc aactccaaaa ggcgatggag agtttaatat ctatgatgat attagagata
     8401 aacttgtggc aatggggata ccaaaagaag aaatagcctt tatccatgaa gctaattcgg
     8461 ataaacaaaa agacgaactc tttgcaaagg taagaaaggg agatgtgagg atattactcg
     8521 gttcaactca gaagatggga gccggcacaa atgtgcaaaa taaactgatt gcacttcatg
     8581 accttgatgt tccttggcgt cctgccgatg taggacggat tttgcggaca ttcaaaataa
     8641 aaaagaatgt ggaggtaaca gacaatggca aagacaattt ttgaggaaat gggcggcaaa
     8701 tacgaaaggc aaggcgatta tttaataccg tgcttaactg tacccgccga agaagaacag
     8761 ccgataggca tctggggaca gcggcatttg gattatctga agcatcactg caaagttaca
     8821 tacaccaatc ttcttacaag cggcagactt aacgcttacc ttgccgacat tgacagacag
     8881 gcacaggaac gctttgaaag gctcatagag ggtatgaaac aggcacaggg cataacggaa
     8941 cagctaaagg cagaaaacgc cttagaatgg acaggatgcc tcaataacat aagggcttgt
     9001 gcgagggaga ttgtggaaaa ggaaattatt tttgcataaa cagatgatta gtggcagggg
     9061 gaaatcctgc cgctttttct gctttagttt gtcagcttga caaataaagg gttaaggaat
     9121 ataattagat tcagtattat acaaggagtt aataaatatg cggcaaggta ttcttaaata
     9181 aactgtcaat ttgatagtgg gaacaaaaag tagcagtccc gtttcacttt taatatgggg
     9241 cttagttttt tgtacccagt ttaagaatac ttttatcatg taattttata tgcccgaaaa
     9301 catataagtg ttttggggct attggagtta tttacccagt gataggagta tttatcactg
     9361 ggtattttta tgcccttttt tgggtgttga taggaggaaa atcacatgaa aataattaac
     9421 ttaggcattc tggctcacgt tgacgcagga aagacaacat taacggagag tttattgtat
     9481 accagtggtg caattgcaga accagggagc gtagataaag gcacaacaag gacagataca
     9541 atgaatttgg agcgtcaaag gggaatcact atccagacag cagtgacatc ttttcagtgg
     9601 gaggatgtaa aagtcaacat tatagatacg ccaggccata tggatttttt ggcggaagta
     9661 taccgttctt tatccgtatt agacggagca gtattattag tttctgcaaa ggatggcata
     9721 caggcacaga cccgtatact gtttcatgca ctacagacaa tgaagattcc gacaattttt
     9781 ttcatcaata aaattgacca agaggggatt gatttgccaa tggtatatca agaaatgaaa
     9841 gcaaagcttt cttcggaaat tatagtgaag caaaaggttg ggcagcatcc ccatataaat
     9901 gtaacggaca atgacgatat ggaacagtgg gatgcggtaa ttatgggaaa cgatgaacta
     9961 ttagagaaat atatgtcagg gaaaccgttt aaaatgtcag aactggaaca ggaagaaaac
    10021 aggagattcc aaaacggaac gttatttccc gtttatcacg gaagtgctaa aaacaatctg
    10081 gggattcggc agcttataga agtgattgcc agtaagtttt attcatcaac gcctgaaggt
    10141 caatctgaac tatgcgggca ggtttttaag attgaatatt cagagaaaag gcggcgtttt
    10201 gtttatgtgc gtatatatag cggaacattg catttgaggg atgttattaa aatatctgaa
    10261 aaagagaaaa taaaaatcac agagatgtgt gttccgacaa acggtgaatt atattcatcc
    10321 gatacagcct gctctggtga tattgtaatt ttaccaaatg atgttttgca gctaaacagt
    10381 attttgggga acgaaatgct gttgccgcag agaaaattta ttgaaaatcc tctccctatg
    10441 ctccaaacaa cgattgcagt aaagaaatct gaacagcggg aaatattgct tggggcactt
    10501 acagaaattt cagatggcga ccctctttta aaatattatg tggatactac aacgcatgag
    10561 attatacttt cttttttggg gaatgtgcag atggaagtca tttgtgccat ccttgaggaa
    10621 aaataccatg tggaggcaga aataaaagag cctactgtta tatatatgga aagaccgctt
    10681 agaaaagcag aatataccat ccacatagaa gtcccgccaa atcctttctg ggcttctgtc
    10741 gggttgtcca tagagccgct ccctattgga agcggagtgc agtatgaaag cagagtttca
    10801 cttggatatt taaaccaatc gttccaaaat gcggttatgg agggggttct ttatggctgc
    10861 gagcaggggc tgtatggatg gaaagtgaca gactgtaaaa tctgttttga atatggattg
    10921 tattatagtc ctgtaagtac ccccgcagac tttcggctgc tttcccctat cgtattggag
    10981 caggctttaa aaaaagcagg gacagaacta ttagagccat atctccactt tgaaatttat
    11041 gcaccgcagg aatatctctc acgggcgtat catgatgccc caaggtattg tgcagatatt
    11101 gtaagtactc aggtaaagaa tgacgaggtc attctgaaag gagaaatccc tgccagatgt
    11161 attcaagaat acaggaacga tttaacttat ttcacaaatg ggcagggagt ctgcttgaca
    11221 gagttaaaag gataccagcc agctattggt aaatttattt gccaaccccg ccgcccgaat
    11281 agccgtatag ataaggttcg gcatatgttc cacaagttag cttaacagct tgcaaaagtc
    11341 atataaaatg agatttgaaa ggattagaga ctaattatga tgaaatgcga atggatattg
    11401 tgtcctgttt gtgggagcaa aacccgtaat aaaattagga aggacactgt tttggagaat
    11461 tatccccttt attgtccaaa atgcagacaa gaaagcttga ttaaagttga caacttgaag
    11521 ataactgtca tcaaagagcc agacgcttaa gacgcagagc cgatgaaatt gtggaacaat
    11581 tcacgaatca tcggctcttt ttgtttcgta tttgaaagaa caaactcacc aaataaaaaa
    11641 aacgatattc gggtgggtta ttttgttata ccctaaatta ccctctgaat ttgtttttaa
    11701 atttggaggg atttttttat gttctttttt cgggcggtta ttcatctgct catacgaagt
    11761 aaaatttatc aatacatagc atatcagaga atggcaggaa accagttaaa aaaatttctg
    11821 ccagtgcagc ggtacttctc accttgaaag tggaagtaca atctccatac aacagaattt
    11881 gtatttccca taaccgtgaa ggtcacagag cctttgcggt ttttcttttg tcgttttttg
    11941 ttggaaagtg ccgcagggct gtttctggtg tgcgttgccg ctccccgcct ctccatctgg
    12001 atttttacat ttcaaaaatt cagattggag gtattagcgg tgaaatacgc accaagaaaa
    12061 gtatatatca aagaaagcgg cggctatgtg gaactgtcct atacggattt ctgccgccgc
    12121 aggcaagccg acaagggata tatggacaag ctgtttatcc ccgtccaagg ttgtctgctt
    12181 gaagtcgtaa gggagcaata tgcggacttc taccgtgaca gggagcggtg gcgttacctg
    12241 caaaaattag atgcgaggaa cagcctgcta tctctggacg gatttacgga cagcgagggg
    12301 aatcctctgg actttatcgc tgatgaagcg gcggacattg cggaaaccgt tgtcaatgct
    12361 gttatggtgg acaggctgaa agccgccctg cctttgttgt cggatagtga gcaggagttg
    12421 atacaggcaa tcttttttga cggactttcc gagcgtgaag tcggggcgag gttaggcata
    12481 acccagagcg ttgtgaacaa acgcaaagcc agaatcctaa gaaaactaag aaagataata
    12541 gaaaattaaa atttaaggcg ttcagccccc ttgttttttc ctttgggaaa atgagggggc
    12601 ttttctctgc cctctcaatc aattctgatt ggaggaagaa agaatggcat acaaccacgg
    12661 acgggaggac aggaaatggc gtatctggaa agaagcggag gaaaagctgc tgcgtgagtg
    12721 cggcgttgat gaagtgacca ttgagcagat acgcatagcg gacagggcag acttcaattc
    12781 caacaggcgg ttttaccgat ggacgaatga cgttgcggaa taccttgagg acatggcaga
    12841 cagggagcgg caagcggagg tgaatacagt tgcggagtta ctggacgaga ttgagagcga
    12901 aaatctctat caagtattag tcacggtgga cgggcgtacc ttgaaaatcg tcctgctgaa
    12961 aatgcagggg tattccacaa aggagattgc cccacttgtg catttgacga ctggtgccat
    13021 ctatgcgagg ttagaccatc tgcggaagaa gcttcggaaa attttgtaag cgtctaatac
    13081 atcccattat tctgcgggct actgggtggg gagtggaatc tccccgctta tttttggcag
    13141 gaggaaaacg ggatggcata taaagctaag gcgtacacgc ttcgggagga atccacggaa
    13201 agcggtataa ggtattttat cagttttaag gacgggcagg gggaacacca cgaactggaa
    13261 gtatccgagc agttattctt tgaatttcgg cagatggaac gcaggaacag gaatcttctc
    13321 caatgggacg agcggcacag ggagttttcg gaagtatggg acgaaacgct gaacaggcgg
    13381 gcgttaaagc tgcctaagag cattgaggaa caaatgattg aagcagaacg ggcggaactg
    13441 ctctgtaagg cggttgacag actgccagag atacaaaggc gacgtttcct gctctactac
    13501 gagtatgagt tcaattttta ccaaatcgcc gctatggagc attgcaccgc ttctgcaata
    13561 cagaaatccg ttgctgttgc aaagaagaaa gtaaaagcgg aaatgaggaa atatctccaa
    13621 ccatgaccga caccgcccga aaaagaaatc tgttttttat ttgtgtggga ttggcggtat
    13681 tacatactct cacttttttc gtgggagtaa atctattttt aaggaggtca acgcctatgt
    13741 gcaacaaaaa caagataact gcccgaaagg aggaaaccca tgcagaagtt acagacagtc
    13801 aacgccgaaa cgctccttta tgagccgctt gagaagccgt cctttgtggt ggacagcctt
    13861 atccccacag gcttgtcgct gttctgcggc tcacagaaga taggcaagag ctggctcatg
    13921 ctgaagctgt gcttatgcgt gtcgcaggga atccccttat gggacatgac gacaatggag
    13981 ggcgatgtgc tttacctctg ccttgaggac acgttctgcc gcatacagga caggctgttc
    14041 cgtttgacgg acgaagcgag cgggcggctt cattttgccg tggcaagctg caagctgtca
    14101 gacggtctta tcgtgcagct tgaggattat ctgaaagact atccagacag caggctcatt
    14161 gtcattgata ccttgcagaa agtccgtaca gcttcaaaag acaacgccta tgcaagcgac
    14221 tatggggaca tctccctaat caaagatttt gccgacaggc actctctggc ggtcattgtc
    14281 gtacaccaca tccgaaagca gaatgacagc gatgtgttca acaaggtgtc tgggacgaca
    14341 ggcttaacgg ggagtgcgga cgctaccttt gttctggaaa aggagaaacg ggcatctgac
    14401 accgccaagc tgtatgtaac gggcagggac acgccctatc aggaatacac gctccgtttc
    14461 cgtgattgca gttgggaact tgtggagagg aaaacgcagg agcagcttgc gaaagaaacg
    14521 ataccagatg tcctttttcg gttggtggat tttatgaggg ataaggaaga atgggcaggc
    14581 acggcaacgg agctgttagc cgctatgggg gaaacggaaa ccatacccac ggtgattacg
    14641 aaatggctga atgaatatca caccacattt ttaagcgaga accgtatctg ctaccagtac
    14701 agccgcagga aagacggcag gcagattgcc cttgcaagga gggcgggtga cagcggtgac
    14761 ggcggtgaca gcgatattgg gataccccct gttactgtca ttgacgctta aagccatgta
    14821 aagttggcgg ctctgccctg cgggtgacag cggtgacggc agtgacagtg attttaggat
    14881 accctgccgc tgtcatccct acgggagaac accccgcaaa cgcaaaatgc aggcgtggga
    14941 ttcacccgcc cttttcgggc gtgtaaaatc acccctgcgg tcagaaaaat ctctccgatt
    15001 tttccgactg cgtttacagg gtgtaacaca ctacactttg ccctgcaaag agccgtgtgc
    15061 cagacgttcc ctctggactc ccttatggca ggtcttacgc cctgctatcc tacgccttgc
    15121 ggcttcggat aaaagaacgg cggcatgacg gttacagctc ttgcgaggga gtatcccaaa
    15181 aacaccgtca ccatcgtcat gaccgtcatg caggggataa gggtgacagt tacggcaatc
    15241 ggcagggggc atcccaaaac tgccgtcacc accgtcaccg ctgtcaccca aagggcagtt
    15301 acccgccgaa gaaaggaaga tgatggatta tgccctatgc aatcctgcgt ttccagaaac
    15361 gcaaagcggg cggcgttgcg gcttgcgaac gccacaacga gcggaagaaa gaagcctaca
    15421 aaagcaaccc agatatcgac atggaacgct ctaaaaataa ctatcatctt gtcgcaccgc
    15481 caaagtacac ctataagaaa gagattaacc gaaaggtagc cgaagcaggg tgcaggacaa
    15541 ggaaagacag cgtgatgatg gtggaaacgc tcatcacggc ttcaccagaa tttatgaacc
    15601 agttaccgcc cgaagaacag aaagcgtatt ttacgatggc tctggatttc atttcggagc
    15661 gtgtcgggga gcagaatatc ctctccgcag tcgtccacat ggacgagaga acgccccata
    15721 tgcacctctg ctttgtgccg attacaccag acaataagct gtccgccaaa acaattttag
    15781 gcaatcaaaa gagcctgtcg gagtggcaga ccgcctacca tgagcggatg tcctcacgtt
    15841 ggaatcagct tgagagaggt caatcttcga tggaaaccaa gcggaaacac gtccccacat
    15901 ggctctataa gttgggcggc aggcttgata agcagtatgg ggaaatcgtg tctgccctgt
    15961 ccgacatcaa cgcctttaac gcagggaaaa agcgtgacaa ggctctggaa ctggttgccg
    16021 catggctgcc cgaagtggag aaattctcta aggaaatcgg cagacagcag gcgtatatcg
    16081 acagcttaaa ggagcaaatc gggcaggaag ccgactatgc agggcgtatg cgtgatgaaa
    16141 agtacgagca ggaattaaag gtgcagaaag ccaaccagag gatatttgaa ttgcagagaa
    16201 ccaacgagca gatggggcgg ctgctctcaa agataccgcc agaagtgttg gaagaattac
    16261 agagaacagg cagaaacaaa tcaagagaaa ggtaaaaagt gaatgaagaa acaggatttt
    16321 aaggtgttaa agaccaaaga tttatacccg tttcccgaca atccgtttca tgttgtggag
    16381 gatgaaacgc tgtcagagtt agcggaaagc atcaaggaat ttggcattgt cacgccgata
    16441 atcacacgcc cgaaagagga cgggaacggt tatgaagtga ttgcggggca gcggcgtgtc
    16501 cgtgcgtccg aacttgcagg tataaatacc gtgcctgcat ttgtcctgcc cttagaccgt
    16561 gaccgagcca tcatcaccct tgtagacagt aatttacagc gtgaaaatat cctgccatcg
    16621 gagcgggcgt ttgcctacag gatgaaatcc gaagccatga agcggcaggg tttccgcaca
    16681 gacttaacct cgtcacaagt tgtgacgaag ttgcggacgg acgacaaagt ggcacagggc
    16741 ttcggcgtgg gcaggatgac cgtccagcgt tttatccgtc tgacggaact gataccgccg
    16801 attttgcaga tggtggacga ggggaaaatc gccctcacac ctgcggtgga actgtccttt
    16861 ttgaagaaag acgagcagga aaatctcttt gccacgatgg agagcgaaga agcaacgccc
    16921 tcactctcac aggcacagcg gatgaaaagc atgagccaga gcgggcagct tgacatggat
    16981 atgatatttt ccattatgac ggaggaaaag ggaaaccaga aagaaacctt gaaaatcaac
    17041 acaagcaaac tgaaaaaata ctttccgaag gacacaacgc cgaagcagat ggaggaaacc
    17101 atcatccgac ttctggaacg tgagttgcag agaaaacgga gcagggacag ccgctaacct
    17161 tcttttttcg ggaagtaaat gcaggaattt ggaacagaag aaagacagaa ttttaaggag
    17221 aatgaggtaa ggaatgaaag aaatccagta tgagattgta aaggaaatcg ccgtattgtc
    17281 tgcgagtgac agcggctaca caaaggaaat caatcttatt tcatggaacg ggagagagcc
    17341 gaaatatgac atccgcagct tttccccgaa ccgtgagaag tgcggaaagg gtatcacgtt
    17401 gaacgctgat gaagcagcgg cactccttga agcattacag aaagaagtaa acagcgggga
    17461 ttgatggtat ctgattgaca gggcggggcg tttccagacg ttctcctgcc ctgtctggaa
    17521 aggaagattt aagtatgggc gaggatagga aaacaactgg aagaagaaag cgtattgtgc
    17581 caaaagggca agtacaaatg attatcagtc gagaatatat cggcacacag accgttgcag
    17641 aagcgtttgt cccgattatc tccgaggata ttcggaagaa gattgccgag ggcgacacct
    17701 tcgacaatga ggggctgtcc gcttagaatg tacgcaatgg aacatgaaaa cgttaggaca
    17761 gatatggagg ttttacagta tggcaggaat aagaacggag aacaagattt atgaagtcgg
    17821 catttactgc cgcttatcaa aggacgatgg cacggataac gagagtgcga gcattgcgac
    17881 acaaaaatcc atcctcacgg attatgtgaa aaggcaggga tggcatttag caaaaacgta
    17941 tgttgacgat ggctactctg gaacaaattt ccaaagacca agtttccaga atatgattaa
    18001 ggacattgaa aacgggctga taaactgcgt gattacaaaa gatttatccc gtctggggag
    18061 gaactatctt gattgtgggt tatatctgga agtctttttc ccagagcata acgtgaggta
    18121 tatagcggtc aatgacggcg tggacacctt aaacaaatcc gctatggaca tcacgccttt
    18181 ccgcaacatc ctaaacgaaa tgtattctgc cgatgtgtca gtcaagataa aatcggcgta
    18241 ccgtgcgagg tttcagcagg ggaaattcat gggaacaaca gccccttatg gctatgtcaa
    18301 agaccctgcc gaccacaacc atctgctgat agatgacaaa gttgcccatg tggtaaggga
    18361 gatattcgac cttgcgttag cgggcaacgg catcgccaaa atccgcaagc acatcaacaa
    18421 acagcatatc ctacgccctg ccgcttatgc ggtggagcaa ggggcaacag gctatgagcg
    18481 gtactttgag gataacgagg aaaaccgtta tatttggagc gagaacagcg tgaggggcat
    18541 tttaagaagc ccgatatatg cgggcaacct tgcaggctac aagcggattg cagccaacat
    18601 gaaaagcaag aaacgcccct ctaagctgcc cgaagaatgg gaagtgatac cagacaccca
    18661 tgaggggata gtcacgcagg aggaatttga caccgtacag cagcttatga cgagccgcag
    18721 gcgggagcag aacgcagggg gatttgagaa tatcttttcg ggcgttatca agtgtgcgga
    18781 ctgcggctat gcgatgcggg cggcgagtgc caacaggagg aaacgccccg acatcatcga
    18841 ctgcgtacaa tacacctgca ataattatgg cagatatggc aatgttatgt gtaccgcaca
    18901 cagcattgaa gcgagggact tattcaatgc cgtccttgcc gacatcaacc gctttgcgga
    18961 tatggcggtc aatgatgaaa aggcggtcag agccatagaa aggcggctca cggaaacaga
    19021 ccagagcagg gcgaaatcat tagagaaaga aaagaagaag ctgaacaaac gccttgcgga
    19081 gcttgacagg ctgttttcct ctctctatga ggacaaggta atggagcgta tcacggagcg
    19141 gaattttgag atgatgtcgg ggaaatacca gaaagagcag cttgaaattg aagcacggct
    19201 gaaagaggta acggaaacgc tcaatgacag ctatgagaaa tcgcagggcg tgagggactt
    19261 tctatcccta atccgcaact atcaggggct gaaagagttg gacgcaacca tcataaacgc
    19321 actcatagac aagatacttg tttcggaacg tgagaaactt gcggacggga cagtaaggca
    19381 ggaaatcaag atttactata aattcatcgg ctttgtcggt gaattacata tcacacccac
    19441 aaagcggtgg acggcgttaa agcctaaaaa ttgtacggtg tgcggtgttg aatacgtccc
    19501 cagctctgga atatcaaagt attgtcccgc ttgtgctaag aggatacaga gggagaaatc
    19561 aaacgagagc aaacgcagga gtagggagag gaaccgaagg gcatgtattg aactgtccgc
    19621 aaaaaatgac cgactgacct tgagcagaga gcaggaagaa ttgtaagaca ggggaacgaa
    19681 aataaagaag taaatatcta tcgttatgtt acagagaata cctttgatgc ctacctttgg
    19741 cagaccatag agaataagca gaagttcatt tcacagatta tgacaagtaa aacacctgtg
    19801 cgtgtagcag aagatgtgga cgaaagttct cttaactatg cagaaattaa agcccttgcc
    19861 acaggtgatc ctaagattaa agagaagatg gacttggata atgaggttac aaaacttaaa
    19921 atgctggaag caaactttaa gtccaaccgt tataggttag aagataaggt cgcaaaaaca
    19981 taccctgaag aaattgcaag gacggaaaag ttaattgagg ctgtaaagaa agacatatca
    20041 gagattgagc cgcaaggaga aggcgaaaat aaattcactt cgataaccat aaagggagag
    20101 aagatatttg ataaaaagat tgcgggagaa aagttacttg aagctatcaa gaccgtaaaa
    20161 atcaatgaaa gtaagattat aggaaagtat agaaatatgg acttggaagt cagctataac
    20221 ttctttacca atgcccatga ctttagctta aatggtgctg caaagcattc aggagagctt
    20281 ggaacaagtg cagacggtaa tattacaaga cttgataatg cccttgagaa aatgcctgaa
    20341 aaactgaaaa gactggagga gaagcttaca agtacaaaag agcagctcga aaatgccaaa
    20401 gaagaactta aaaagccgtt tgaaaaggca gatgaactaa agagtaaggt gcttcgtttg
    20461 gcggaactga ataagctgct tgatatggga gatgtagagg aaaaaagaaa tgataatcct
    20521 cttgtggaag atgtaaaaag agcgattatt gatttctgta acagagaata tgatgaaaat
    20581 tatagctatg atgagtttga cacattatac cctgatttaa agcatatagg gattgcctat
    20641 accaatacac cggatgaaag gcatggtatt cagtatgagc ttgatttaga ggagaaaact
    20701 tggacgcagt acattgatga tactcctatc aagacagaaa gctttgacta tgaaaacaag
    20761 ggagagaatg aagctctaag gaatataaaa aatgaaattg agttatcctc ttttgaagat
    20821 ttaacctatg tagattcaga ggacttaaaa gtagcacttg ggcttgatat tgatgatgaa
    20881 ggtaactttt atgatccact tgcaaaagac ctcgataatg acggtatttc tgataggtat
    20941 gataatgact ttaaggacag cgactatttt gagtcaacct ttgatgtgga agataatgtt
    21001 catagtaaag gagaaactac acaaaaatca gaggataagc cgtctatttt atgtcagata
    21061 agagcctatc aaaacgaaag taaaacagaa gaaaaaccaa caacaaaaga acaggaatat
    21121 gtacgataag ggagcgaaaa gctcccttat gccatgaaag gagaacaaaa tggattacaa
    21181 aacaatgaga gatagaattg aagacatggt aaatgataac cataaagatt ttgttaaggc
    21241 aattataagc atggaaaagg gcattaacga tgaaagtgct ttagataagc tctatgatgc
    21301 gtatatggaa aatgacactg ttaatttact tcacgaggaa tttgattata tgattgagga
    21361 tttgagagaa cagggacaga taaaagacct gccttatgtt caggaagaga aagataacct
    21421 tatcaatatc gtgggtaata ttgtaggtaa agtcgatgtt attgagagag aaaacaaaaa
    21481 cggagaagcc tttaaggtgg caaatttctc cgttgtatct aaagataatg aagggaataa
    21541 ggtatatcat aattgctctg cttacggaga taagggtgat ataccaaagg attttaaaca
    21601 gggagatttt gtgaagctct ttgggcaaat cagaacttcc attgatgata atggcgggga
    21661 acatagtaat gtaaggatac tttcttcaaa gctcttaaag gcaaaggaac aaatgaaagg
    21721 acaggaggaa aagaaagaat ctgtacttgg agctatcaaa aaatatcagg ctgaagataa
    21781 agaaaagcct aaagaaaaga aagaagcaaa cagagaagct gagagataaa tatatggtcg
    21841 gtgtggtctt agggctgcac cggctctttt tttatttgga aaagaaatag gagataaaga
    21901 ttatctctcc atctccttac ccatgtaaat tccataattt tttcgtatct tgtaaagttc
    21961 gtccataata gattttgagg aagaatactc ttgcataagg gtattctttt tttcttgtaa
    22021 tttatcaagt ctatctaaaa tacccttaga atttggcaat ttggaatatg attttttaag
    22081 ctctgaaagg gcattttcat atagggtaat ctgagctttg tactcttcaa aaaatgcctt
    22141 gtcagacgga cttgccttat attctttgta gtattgcctg tattttttaa cagtgtgaac
    22201 ttgctccata gtggcagaaa gctcttgcat ttccttatca ataaccttaa tcttatcctg
    22261 taaattttgt ctttcatcgg ctgatttttg gatatattca tcaagttgct taacggattt
    22321 aataccttgt tctctaagga agataataga ctcagccatt gtgttaaggt tatgtttggt
    22381 tgcccaatat tcgtaacctt tgctttcctt tacctttgta ttggtgttca tatcaataac
    22441 attgccgatg cgttttttga cagtggagtt tttaatagat actatttctg caatgcgttc
    22501 ttttaacctt tcttcagtat aatcttctcc gatagtttta gctcttgtaa atcttggctt
    22561 atcttttggc ttaaaagcaa tgtgtttgcc atacttaatt tcatagccaa gatcagccat
    22621 tttctttaga aattcatccc aattattaga ctgatttatc attctgtcaa tgtcaaattg
    22681 aagcctgctc ttccaagaag tgccacgctt tacctgctcg ttttcatacc atgacttgcc
    22741 atttgttttg tattttttct tgtagctttc gtaaaactcg tcaatgacag ataggttatt
    22801 ttctttgcac agcttatcac tttgatacct gatttgatga tagctttttt tattagactg
    22861 gtagcatcta cccgttacca tatttacatt attgaagatg atgtgattgt gaatatgtcc
    22921 tttgtctatg tgagtagata aaacaaattc gtactcgtct ttgagtatct ttttacacag
    22981 ctctataccg atttggtgtg ccattttagg cgtggtttct cccggtaaaa aggattgaat
    23041 gagatgtctt gcaagaacag ttccctttgt tcctgcatca tttcgtgtcc ttaaaaattg
    23101 agtatgagca gttgactcat ggcatttatg cgtgctgact aaaatctgct cgtctgtttt
    23161 atctccattt acaatgtatt cgatagcaag attaagggtc gatttgatag ggtgtatttt
    23221 tgtgatcgcc ataaaaacta atcacctcct gaagtcctgt taagcagcag tgaatgaatt
    23281 tgccatagct cttttgagaa atgttcaatt tgttttttca tatcattgat gtcctctttg
    23341 taaattatac ctgttgaatt tactcgcttt gcaatctgat tgatgttatt tgtggcatta
    23401 gaaagcaagc cttgtaaatt tcggaaaggc tctaaatcta cttgataaat ttccttttcc
    23461 aaaacacatt tgcgtataaa atggctcata tttctgcact ttgcaagttt tcttttctct
    23521 tcaaaaagag ccttttcttc ttctgttagt ttaatttcaa gtctttcatt tcgtattcta
    23581 tttgccatag gtagttcctc ctttgaatgt atttcggggt cttagggttc tccctaacaa
    23641 gctaaaaatt gataaaaaaa gaagcagatc ccagagggct gcttcatcaa ttttttcgta
    23701 agtgtccgta cacttactgt gcttgctaca aaagaatgat tatggtagca agcattaagc
    23761 aagttttaaa tgtatatctt atattgtacc aaatgagata agtaatgtca tcagaattga
    23821 aaaaatgctt ttaatatgac aacatatgtc aagttaatat ggtataataa atataggaga
    23881 tgttaagacg atgaaagata ataggctatt taggatacta tattatattt tagaaaaggg
    23941 aaaagttaca gcaagcgaac ttgctgataa atttgaggta tcagtcagaa caatttatag
    24001 agatattgac tctatcagta gtgcaggtat tcccatttat gcgttgcaag gaaagggtgg
    24061 tggaatagaa attgctgagg attttgttct tagtaaatca ctactgtctg aaaacgagaa
    24121 acaacaaatt atgtcagctc ttcagggatt ggagaataca acaatacaac atgagaatga
    24181 gcttctaaca aaactatccg cactctttaa aataaaaaat accagttgga tagaagttga
    24241 ttttaataat tggcaaaaca ataagatgta tgaaaaaaca tttaatgata ttaagtccgc
    24301 aattttaagt aagaacattg tttcattcac atattttagc agtaatgaaa aagaaacaag
    24361 cagaagagtt aaacctgtga gattgctttt caagagtcag gattggtatc tatatgccct
    24421 atgtttactc agaaatgatt tcagatattt caaattgtcc aggataaaga atttagaaat
    24481 ccatactgaa aagtttgatg acaactttga agatgtaata ctcaaaaaag aaacgccaca
    24541 tgagaataca gtgaatataa aagttaagtt tgatcgaaaa gttgctttca gggtatatga
    24601 tgaactaaac ggagaaatta cagaagataa tgacggaaat ttatatactg aaa
//
LOCUS       DARYSY010000030        24523 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYSY010000030 DARYSY010000000
VERSION     DARYSY010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24523
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..247
                     /locus_tag="TVR04_001135"
     CDS             <1..247
                     /locus_tag="TVR04_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269832.1"
                     /translation="NSMKNDFCRMRKELREELGFDSYGWSDSFRNMRRDIKSNKELIS
                     EINSLQIIKKAKEAKRLEELEQTKANVEKEINKLNGR"
     gene            339..530
                     /locus_tag="TVR04_001136"
     CDS             339..530
                     /locus_tag="TVR04_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269833.1"
                     /translation="MKIEIFLKEGPTKSVSNYGENCIDEVVGAMKNNDVIALEGKNNA
                     VIIPKQNISHVIIHKEVTG"
     gene            527..943
                     /locus_tag="TVR04_001137"
     CDS             527..943
                     /locus_tag="TVR04_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1269834.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIACTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            1033..1485
                     /locus_tag="TVR04_001138"
     CDS             1033..1485
                     /locus_tag="TVR04_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1269835.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLDSEKIADQKEVLQYLSSVMRGEQQEKTLISIGEFGQ
                     EIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            1475..2752
                     /locus_tag="TVR04_001139"
     CDS             1475..2752
                     /locus_tag="TVR04_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1269836.1"
                     /translation="MTIKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVIKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            2768..4300
                     /locus_tag="TVR04_001140"
     CDS             2768..4300
                     /locus_tag="TVR04_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1269837.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNEDKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTRLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGAKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            4260..5708
                     /locus_tag="TVR04_001141"
     CDS             4260..5708
                     /locus_tag="TVR04_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1269838.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYSE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQSFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRLDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFSCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     YKPQLSLLNEYVKNGTPYKVDGHRVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDGVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGR"
     gene            5736..5924
                     /locus_tag="TVR04_001142"
     CDS             5736..5924
                     /locus_tag="TVR04_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269839.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIITELKKVG"
     gene            5927..6193
                     /locus_tag="TVR04_001143"
     CDS             5927..6193
                     /locus_tag="TVR04_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269840.1"
                     /translation="MNKRIKKKRKLETAIVMLVAENAMQAEAIKNQNRQIAELRAIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWGK"
     gene            6349..6918
                     /locus_tag="TVR04_001144"
     CDS             6349..6918
                     /locus_tag="TVR04_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1269841.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            6931..7818
                     /locus_tag="TVR04_001145"
     CDS             6931..7818
                     /locus_tag="TVR04_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1269842.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAISEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            7830..8186
                     /locus_tag="TVR04_001146"
     CDS             7830..8186
                     /locus_tag="TVR04_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1269843.1"
                     /translation="MGDKQLIDDIKLFIGISKEDGAQDELIILAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            8197..8475
                     /locus_tag="TVR04_001147"
     CDS             8197..8475
                     /locus_tag="TVR04_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269844.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRAVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            8472..8816
                     /locus_tag="TVR04_001148"
     CDS             8472..8816
                     /locus_tag="TVR04_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1269845.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQQLLHYRVVSPALYSVYLELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            8820..9179
                     /locus_tag="TVR04_001149"
     CDS             8820..9179
                     /locus_tag="TVR04_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269846.1"
                     /translation="MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGVVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            9191..9790
                     /locus_tag="TVR04_001150"
     CDS             9191..9790
                     /locus_tag="TVR04_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1269847.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNIAR"
     gene            9844..10299
                     /locus_tag="TVR04_001151"
     CDS             9844..10299
                     /locus_tag="TVR04_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269848.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            10374..10607
                     /locus_tag="TVR04_001152"
     CDS             10374..10607
                     /locus_tag="TVR04_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269849.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            10622..14779
                     /locus_tag="TVR04_001153"
     CDS             10622..14779
                     /locus_tag="TVR04_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1269850.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPQPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     NTVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDTMNRFPKTMALFGYSTEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALISTVLGDFAHTGELSGQTLDKLKAKIASLAPKVIALWAVMNPVSAIATIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIDQLLNTAVTKGPGIIQ
                     GLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQLITSLVKGIGQNATSLI
                     SSAIKIIGSFVSSIVSALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNIPQIVQSAVQIIQSLVSGLTQALPQIIAAGIQLVVQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLEAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     AMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVSAQTGTMS
                     LQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     ANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSSVTSGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFA"
     gene            14791..15633
                     /locus_tag="TVR04_001154"
     CDS             14791..15633
                     /locus_tag="TVR04_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1269851.1"
                     /translation="MDLLIEKESQAARLSDFGIYNIAIEDSAPLLSVSHRTVKGRSGH
                     IYDGATFTTKTLKVKGRVTVGNVEGFLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGDSTGDLQLIGSPHKPWKYRFKVILDDTITYEFVGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            15643..17625
                     /locus_tag="TVR04_001155"
     CDS             15643..17625
                     /locus_tag="TVR04_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1269852.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDYSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDQELEEFRETL
                     KNLSLPEEAIKKITDAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGDPNRTKTYDEDYIEVEANDGGFKRGETYTISFSQTCELLKKVAITLTQANN
                     KGIKLTLTPTKAKMDAQTFDLTKDKEVISVYPLSYSATLTGDWYKSKQVDLNASDTQE
                     LALGMAYKDVVDGNSADLVLNWAENPDIIFDGNGGI"
     gene            17667..18749
                     /locus_tag="TVR04_001156"
     CDS             17667..18749
                     /locus_tag="TVR04_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269853.1"
                     /translation="MSTQEWESSSDILMEREIGIDMTTGYPKVGDGKSRFSELNDLRG
                     PMGPQGPRGERGPIGPTGPIGKTGETGPQGPPGPAGATGPKGADGKMTFEQLTKEQRE
                     QLKGDKGDPGPRGADGQRGETGPIGPPGKDAVLPDDVVRKPDLTAYATKDELKKISVG
                     QAIPVFTTSYQYDSGYLKYYSDSYRATWSVNEDASKLLAGDIVALEITNTSERAKNYL
                     IVSVVSSSRSSITSISRELSKDKPEGTTFLTQKDADKIYATKQHKHEIDDINGLQSAL
                     SHKANAQHSHSEYLEQSTADSLYLAKHEIEGYLSSYVRQAEIRSLIDNIGKLKDETTG
                     QYLSVKVVDKGNVPYDTSGMIVFERA"
     gene            18752..19375
                     /locus_tag="TVR04_001157"
     CDS             18752..19375
                     /locus_tag="TVR04_001157"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269854.1"
                     /translation="MAMQEIKDTFFYKIDGQTIGYSLLQKSGLSLGQFYIKISDRYNF
                     NAGRDVDIYKIISSTQADVYKANKYNYQSLSETELSAPQPPTSPPAPKNDSLYQSITI
                     DGRAIGRVICNNQVVWQKQGRSTSASGGWQQLWQGNLSLDDVRLPGYQIYFFKSDYDS
                     FIRSATDLIGSYESINGNTLIARYDHSNNQLLVSGFGQNPVTIYGKN"
     gene            19386..21401
                     /locus_tag="TVR04_001158"
     CDS             19386..21401
                     /locus_tag="TVR04_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1269855.1"
                     /translation="MSRDPTLILDESNLVIGKDGRAYYTFTASQDNQKVRLASDCLGT
                     AHFNQVMIERGDKPTNYVAPVVIEGSGVETGLFKDLKEISLELTDTENSNLWSKIKLN
                     NRGMLQTYFDTTIKNEILTTAQGIRETISDTERGLKSEFLKTVQGQRIQLESLLEQKT
                     AQLGLTVDGLRLDLNKADKQTASLQASIEGLRQDYKDADRQLSGSYQSGIEGLKAQLA
                     NDKLGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAYESKLEGLRAEFTRSN
                     QGMRTELESQISGLKAVQQSTASQISQEIRDRTGAVSRVQQDLASYQRRLQSAEGNYS
                     SLQQTVSGLQSDVRSPTGKIQSRLTQLQSQIDQRVTRDGVMSIINQSGDSIKLAIQKA
                     GGIDAKMSASEIISAINLNGYGVRISGERIALDGNTTVNGAFGAKLGEFIKLRADNII
                     GGTIDANKINVININASSIVGLDANFIKAKIEYAITSLLEGKVIRARNGAMSIDLQTG
                     QINHYTDTSAMRRIDSSTASQFIKMTKSGFVSEIGRTQAAMTVIGSNSDGSESHDNAG
                     FAGMRTWNGTVGYQSTSLIELVGNRVTIYSNKNRSPWLFDSTTPGYAYLIPQNDNGTK
                     HMIGRADRKIDQIYVGDIFVQGERVAMMLKDLANRIGFYGGWASRIG"
     gene            21414..21842
                     /locus_tag="TVR04_001159"
     CDS             21414..21842
                     /locus_tag="TVR04_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1269856.1"
                     /translation="MQLTIKNKDLNTLHSVLDKIKVTNMRANRGRAKLLAKVEAKLSE
                     YAKDEVDIIDQYVAKNDDGKWITDDKGNPKIDDTSKLAELNDFLDELASEPIIIKGGE
                     YSKRFIDFLEYLAESEDEFTSEEIVLIDNILEQFEESKGE"
     gene            21845..22465
                     /locus_tag="TVR04_001160"
     CDS             21845..22465
                     /locus_tag="TVR04_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1269857.1"
                     /translation="MRNWKVTGKYPQYDSAGAVASTHVIIAAEDGAVIPQLVKRDLTG
                     TNDKDIIAAVLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIEPAKKGEYQAYDVFTVVDESHEEQ
                     AGEGNLVFVHVNEPFTYEAQTLKELKELEEEGKVTVIKYADLVKQD"
     gene            22476..22796
                     /locus_tag="TVR04_001161"
     CDS             22476..22796
                     /locus_tag="TVR04_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269858.1"
                     /translation="MHEILIQIKELAGAVSALALIGGAMIWIYKKLVIEPDSRLAKRL
                     QVENNKLLTDTVNPLTDAIKDLNYNLNTATKERAEMRKDIEVHEGRLDAHDIRLTVLE
                     TKEK"
     gene            22798..23130
                     /locus_tag="TVR04_001162"
     CDS             22798..23130
                     /locus_tag="TVR04_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1269859.1"
                     /translation="MQEITNIITGSSLSILTILAGIVVKLVKDYLLKKGGEKAVKIAE
                     IVARNAVEAVEQIAYDKDIKGIEKLTEAKVAVRDELSKHNVYLSEKQMEVFIEAAVKR
                     MNDNWKGQ"
     gene            23132..23884
                     /locus_tag="TVR04_001163"
     CDS             23132..23884
                     /locus_tag="TVR04_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1269860.1"
                     /translation="MATLDEVLSFAKGLADAGQGVDLDNVYGTQCVDLPNWITTKYFG
                     IALWGNAIDLLDSAAAQGMEVVYNAPGVNPRAGAIFVMVTYAHGYGHTGLVIVTSDGY
                     VLHNIEQNVDGNADALYIGGPARYVDRPFEDGTGYILGWFYPPYDSTPAAATEPSAPV
                     VAQSDGTYIANPETGTFTVRVAALNVRSAPRLDAEIVATYGENMEFNYDGWIDSDGYI
                     WVTYISATGVRRYVAVGNSQNGRRVTNFGTFR"
     gene            24175..>24523
                     /locus_tag="TVR04_001164"
     CDS             24175..>24523
                     /locus_tag="TVR04_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEL1269861.1"
                     /translation="MKQPLALTWEDQIRLFEKRGLIVKADDVEKIKHISYYRIKEFAK
                     PLEIKRQDGEEKDILYDNIEFAEVLARYYQDKNLRIYLLHAIEKIEVAIKTKISFVLG
                     DRYGAFGYLNFSSW"
BASE COUNT         8119 a         4330 c         5503 g         6571 t
ORIGIN      
        1 taattcgatg aaaaatgatt tttgtagaat gcgtaaagaa ttgagagaag aactcggttt
       61 tgatagctat ggctggtctg acagtttcag aaatatgcgt agagatatta aatcaaataa
      121 agagttaata tccgaaataa actctttgca aatcataaaa aaagccaaag aagctaaacg
      181 actagaagaa ctcgagcaga caaaagcaaa cgtcgaaaag gaaatcaata agttgaatgg
      241 gagataagga tggacgataa tacagcagtt gttttgatac tgctaatact atttttaccg
      301 attattatta gtagttttag agattaagcg aggaaaaaat gaagattgaa atttttttaa
      361 aagaaggtcc tactaagagc gtttctaatt atggtgaaaa ttgtattgat gaagtagttg
      421 gcgcaatgaa aaataacgat gtcattgctc tagagggaaa aaacaacgca gttattatac
      481 ctaaacaaaa tatttctcac gtaattattc ataaagaggt aacgggatga gtagattatc
      541 taatgcacag ctaaaggctt ttgacgaatg gctgtttgat tatcgtttta ttgataacaa
      601 gattgcactt cgaaaacttg agctacaaac tgatatgaat acagaagtag ataaaaatat
      661 cggtggagga agagcaaatt ttgtttcaaa agttactgag gatgtggttg caaggtggga
      721 ttcagatagg gaactaaagg gtctatccaa tttcaaagaa gcagttattg caacgctaaa
      781 tcttttggat gaagaactaa ctgatatttt taatcttagg tggggcgttg gctcaagtaa
      841 cacttgggaa gaaattgcct gtacaagaca tctgtcgcgt aagtctattt accgcaaaag
      901 agagcggatt ctagaaatat tctccaaaaa aataggaatg tgacacaaaa atgtatggaa
      961 ttgtcatctt tttgatgata aattgatagt atgagtttaa aggtaaggca aatagtgtct
     1021 tgcctttttg ttatgcttgg aggtgatgga aaattgagta aattaaccct aaaacagaag
     1081 cgttttgcag atgagtacat catctcagct aacgcgacag cagcggctat taaagcaggg
     1141 tatagtaaaa agacagcaag gtcaataggt caagaaaact tgaccaaacc tgacattaaa
     1201 gcttatatag acgagcggct cgaaaaactt gattctgaaa aaattgccga tcaaaaagaa
     1261 gtgttgcaat atctttcttc agttatgagg ggggaacaac aagaaaaaac acttatcagc
     1321 atcggcgagt tcggacaaga gattgttgac atcgatgtgg gtgcaaaaga tagaatcaag
     1381 gcagctgagc tactaggtaa gcggtacaga ttattcactg acaaggttga aatggatgtc
     1441 agctcagatg taaccattaa cgtaggtgag tgggatgacg attaaacagc gccctaaaat
     1501 taatatcgta atcaagcatc ctagcaaagt ttttaacaaa catatctacg acaaacttta
     1561 caactatagc aacttcacgg aagttcatta tggtggggcg tctagcggaa agtctcacgg
     1621 tgtttttcaa aagataattt taaaagcact taaccccaaa ttcaaacatc ccagaaagat
     1681 attagttctc agaaaagtcg gtgcaaccgt tagagactct gtatttgctg atatcatgtc
     1741 taatttgtcg tatttcggca tcttggataa atgtaagata aatatgtcgg cttttagaat
     1801 aacgctcccg aatggctcgg aattcatttt taagggtatg gataaccctg agaagattaa
     1861 gtcaattaag gggatatctg atgtcgtcat ggaagaagct agtgagttta cgcttgatga
     1921 ttatacgcag ttgactttgc gtttaaggga taagaaacat ctagagaagc aaatatactt
     1981 gatgtttaac cctgtgtcaa aagtaaactg ggtttataaa gccttcttcg ttaagacacc
     2041 taagaataca gttgtctatc aaacaactta taaagacaac cgcttcttag atgatgtcac
     2101 gagagaaaat attgaggaac tagccgatag gaatgaagct tactacaaaa tatatgctct
     2161 tggccagttt gctacacttg ataaactaat ttttcccaaa tatgacaagc aaatattaaa
     2221 caaagacaag ttatcacact tgtcttcttt ttttggtttg gactatgggt ttatcaatga
     2281 cccttcggca tttttgcatg ttaaaatcga tgacgcaaac aagaagttat acatcttaga
     2341 ggaatatgtc agaaagaatt tgaccaatga caaaatagca aatgctataa aggacctcgg
     2401 ctatgccaaa gaagaaatca gaggagattc ggctgaaaag aaatctaacc aagagctgag
     2461 gaatttaggt attcctagaa tgattgatgt tatcaaaggg cctggaaccg ttatgcaagg
     2521 aattcagtac ctgcttcagt atgattggat tgttgatgaa aggtgtgtca agactattga
     2581 agaactcgaa aattacactt ggaagaaaga caagaagact aatgagtata tcaacgaacc
     2641 agttgacagt tataaccact gtattgacgc cataagatat gccgtacaag acagaatata
     2701 ccagtcggcg gatagaagta agcgcatgaa aaatgctaaa tattattttt aggaatgagg
     2761 tgagactttg gaagaaaaac aatttttagc aggaactcgt tttaatgaga atgctaataa
     2821 gcaatttatt atgctgcaag aagactttga agcaattgac tatgaatcaa aactttggat
     2881 agatcaactt aagaattaca tttcaaggtt taaagcagaa caattagagc gtttgaaaga
     2941 gttaaagcga tactatcttg gggataataa catcaagtat agacctgcta aaacagataa
     3001 atacgcagcg gataatcgta ttgcaagtga ttttgctaaa tatattacgg tatttgagca
     3061 aggttatatg cttggtgttc ccgttgagta caaaaatgaa gataaagatc tccaggcagc
     3121 tattgacctt atgtcggtca gaaacaatga ggactaccac aacgtcaaaa taaaaacaga
     3181 tttatcaatt tatggaagag cctacgagct gttaactgtt gaggaaatag atgacaaaaa
     3241 aaccgaagta aaactctacc agctcccagc cgagcaaact tttgttatct atgatgatac
     3301 ataccagcga aattcgttga tggccgttca tttttacgac atagattatg gctcaggtaa
     3361 acgcaaacag attatcaaag tatatacttc cgacacaatt tatacctacg aagactataa
     3421 tctcgaaaca aaaggtacgc gcttaaaaga gcatgaagaa catttcttta aaggtgtacc
     3481 agtcaatgaa tatgctaata atgaggagcg tacaggggct tatgagtctg tacttgataa
     3541 tattgatgcc tatgatttat ctcagtcaga gcttgctaat tttcaacaag attcagtcaa
     3601 tgcgttgctt gtaatagctg gtaatgctta cacaggggct gatgagaatg actacttaga
     3661 tgacggacga ttaaatccta atggtcgttt agcgatctca attgggttta aaaaagccca
     3721 agtgttaatt ttagacgata atcctaatcc aaatggcgct aaaccacaag cgtactttct
     3781 caaaaaagag tatgataccg ccggtagcga agcctacaaa aatagactag ttgcagacat
     3841 tttgaggttt acttttacgc cagatacaca agatatgaaa ttttcaggag ttcaatctgg
     3901 tgaatcaatg aagtataagc ttatggcttc tgacaactat cgcgagaagc aagagaggtt
     3961 gttcaaaaaa ggcttaatgc ggcgcttacg cttagcagct aatatctggg ccatcaaagg
     4021 gaatgaagca actacatata gccttgtaaa tgatacgagt atagttttca cacctaatct
     4081 tcctcaaaac gataatgaaa ttgttacagc tgcacaaaat ctttatggca ttgttagcga
     4141 tcagactatc tttgaaatct taaacactgt cacaggagta gacgctgaag cagagcttga
     4201 acgtttgaaa gaagaagctg ataaaaagca atctttaccg gagcctagat tggtaggtga
     4261 tgctagtggt caagaagaac caacagcaga aaagccttaa ttactggcaa aagcgtcaag
     4321 aagatattct aagttattta gacagagctg atttagatgt cttttcagaa ctgcagaagt
     4381 tatatagtga acaggctttt gagttacaaa aggaattgtt tgatttttat actaagtatt
     4441 ctgaagagaa taaaatgact tatcaggatg tcgttaaaaa gctacgtcat gaagatttat
     4501 cagattacgt agctaatgct aacaagtatc gcaaacaagc tgagaaagac cctgagctgc
     4561 taaaacgact taatgagcag tatgtatcag caagagctac aaggatggat gcattaaatc
     4621 ttgaacttgt ttatcgcgca gggatactaa aaggtgtact tgattcagca tttgaaaatc
     4681 atttaaaaaa agctgcctca tatgcttata aaaaagcaat gggtggacgg tcagggacaa
     4741 tcaatggtcc agttttagaa gaactggtta gaaccccgtt tgatggttat aactattcag
     4801 aacagctgtg gggcaatact gacaatcttg tcaagaatct ccaaaagaaa ttaaaacaaa
     4861 gttttgttcg tggcgagcat cctagagcga tagccagaga tttagctaag caatttaatg
     4921 ttgccaatca cagggctgaa acactaatca gaactgacgg aactatggtg attaataatg
     4981 ctaccgctag gcgctacttg gatgcaggcc ttaagtatta tcgtgattta gttaggcttg
     5041 atgacaggac aactgagata tgtcgtaaaa tcgctaaaga aaacaaaaga aagctattat
     5101 ctgagctaaa gcctggaatt aatgcagcac cttatcattt cagctgcaga acaaccatta
     5161 ttcctgatga agatgagcta agcattgaag tagaaccaat tgatgataaa agcactaagt
     5221 attttaagga tgtcacctca gattggatag atggaaatga gtataaacca caactgtcac
     5281 tactaaatga gtatgtaaaa aatggcactc cttacaaagt agatggccat agggtcgttc
     5341 ttgatcattc gaattatgaa tatagagttg ctaattggtt atctaaaaag acaggattgc
     5401 aagttgacat ggtgccaaga gttaattccc ctgaacatat caatactcct gattatttag
     5461 ttgatggagt tccttttgat ctaaaagaaa tcacaggttc gggtaaaaac gtcattgatg
     5521 gcaatctacg aaaagcaaaa aagcaggcaa ctaatatcat ttttgatata acaaaaaccc
     5581 ctttatcatt tgaagagata atggggcagt tagaacacat ttatatgata gatcgtaggg
     5641 gtcttgatat atcaattatc aaaaataaag atgaggtatt agctgtatta gaaaaagaag
     5701 gacgatgacc caccgcctcc acagtaaact gcttcgtggg cgttagacca tcatccttct
     5761 ttatctcaat tatacatcac cctattaaaa ctatcaagga ggaaaatatg tttatttggc
     5821 aaatggtatt agtggcacta ggtgtattgg tgctcatatt gattgttggc attgcagcaa
     5881 tagcggttaa gtcaattatt acagaattga aaaaggtagg ataaacatga ataaacgcat
     5941 caagaaaaaa cgtaaattgg aaacggcgat agtgatgctg gttgcggaaa atgctatgca
     6001 agcagaagct attaaaaatc aaaatcgaca aattgcagag ctgagagcga ttatacaaca
     6061 aaacgcccaa gcaacaaata gagagtttgc agcagttaaa tcagcgacgc tagacaacca
     6121 agcagccatt aagaaaattg gtgatgaggt ttattatatc aagcaaaatt ataagcgtaa
     6181 atggggaaaa taaattttaa acgaattcga cccttttaga aatcaaagtc gtagcaatac
     6241 ggcttttatt gtgtccaaac tttgttgatg acactaaaag ctacactgtt tcgtcgcagg
     6301 acgtaaagct agactatcgg ttggtggcgt aaccactagg agaaagttat ggcagaagag
     6361 aatgtaacaa cagaaacaac tgagcaagtc gacactcaaa aagaagctgt tgaacatcct
     6421 aagcaggaac atgagcgaac ttttactcgc gcagacatct caaaaatgat ggctgccgaa
     6481 cgcactaaat gggaatctga acaatcagaa gctattgaaa aagctcgtac agagggtgaa
     6541 cgtttggcca agttgtcaaa agatgagcgc gctaaagagg aggaacaaaa acgtctagat
     6601 gctatcgcag agcgtgaaaa agcagtagca gagcgcgaga tgcgcattga gacgcattcc
     6661 ctgcttgtgg agaaaggatt gccattggat tttattgata ttgttttagc cactactgca
     6721 gaagaggtta aggccaatat tgataattta caaactattt ttgataaagc tgtcgaaaaa
     6781 cgtgttaacg atcgtttaac ccagaagcca ccacgaactg gaaacggctc ggtcggtatg
     6841 actaaggctg acatcatggc aatagaggat gatgacgaac gtatgcgttt aattgctgag
     6901 aatcgtaact tattttaaga gaggaatatt atggctgaaa aaaatttaaa cactatggcg
     6961 gacttaggag atattaaatc aattgatttt gttaacaagt tttccaaaaa tattaatgat
     7021 ttactaaaat tgctaggggt tactcgtcgt gaaacgttaa ctaacgatct aaaaattcag
     7081 acctataagt gggaagtgac tttagatcaa actgatcctg gagaagggga aaccatccct
     7141 ctgtctaagg ttactcgaac taaagataaa gactatacag tgaagtggtt caagaaacgt
     7201 cgtgcaacta cagctgaggc aattgctcgc catggcgcag ctcgtgctat ttctgaagca
     7261 gataagcgca ttatgcgtga gcttcagaat ggaattaagg atgcattctt tacattcctc
     7321 aaaacaaaac caacaaaagt taaaggcgtt ggccttcaaa aagcgctgtc tgcatcatgg
     7381 gctaagctag ctacttttaa tgagtttgag ggttccccgc ttgtttcttt tgtctctcct
     7441 ttagacgtag ccaactatct tggagatact aaagtaggtg cggatgcctc taatgttttt
     7501 ggaatgacat tgcttaagaa ctttttgggt atgcaaaatg tgattgttat gccatctgtg
     7561 ccagagggta aaatctactc aacggctgta gagaatctag tttttgcgtc tttaaatgtt
     7621 aaaggcggag acttgggtgg tttgtttgct gattttactg atgagacagg tttaattgct
     7681 gcagctcgta atcgtcagct ttctaatctt acctatgaat ctgttttctt tggagcaaat
     7741 gtgctgtttg ctgaaattcc tgaaggggtt gtagaggcaa caatcgaagc tgctgctgta
     7801 cccggcattg gtggttaaag gctatttata tgggggataa acaacttatt gacgatatca
     7861 aactctttat aggcatttcc aaggaggatg gtgcgcaaga tgagctcatc atccttgcta
     7921 tatctgaaag taaagagcgc gtgctagcta aacttaatga atactcagaa actgaaatca
     7981 ccaaaattcc tgatagattg aggtttattg tccgtgatgt tgctattaaa cggtttaata
     8041 ggattaattc agaaggaacc gttgaagata gcgaagaagg aaagactttt aagtgggaca
     8101 gttaccttaa agagtatgaa tcaacactca gaagcgctgc tattgggaag gtatattcag
     8161 gcaaaggggt agcaagattt atttaggaga tatacaatga tctataaaga tagagtaatc
     8221 ttagtgtatg tcgatgagca ggacgatttt ctagataaaa gagccgttga aaaacctagc
     8281 gggaaaatcc cctgtatgga aaatactttc acaaaatctg aacagatggg gctatttggt
     8341 aaatatgatt tgaatgcttt taagttgcac ttgcaaggcc attacgacgg ctttagcaag
     8401 attatctaca agggaaaacc gaggttgata aagggactag cacaccataa aaatagcacg
     8461 gttatttatg tatgagtctt atttatcgga tgagaggcct agataggttt ttacgcagcg
     8521 ttgagcgcaa gcagaagtca gtacgaatcg ctgtagataa agagcttagt aaatcagctg
     8581 ctagaattga gagacaggct aaaatactag ccccggttga tactggatgg ctgagagctc
     8641 aaatctacaa cgagcaacaa caactcttac actatagagt ggtttctcct gctttatatt
     8701 ctgtttatct tgaattaggt actcgtaaaa tggaagctca accgttttta gaccctgctc
     8761 tgagaaaaga atggcctgtg ctaatggcta atctcaaaaa aatgtttaag aggtgatgca
     8821 tggactactc accagaaaca ctatatttaa aaaaggtaaa aaatagattg ggagttttgg
     8881 acataccaat ctattttaaa ttgcctaaat cagacgtttt agagcctttt attgttgtgg
     8941 gtacaaatat atcagacttg tcaaaaacag ctcaaactgg agtagttatt gacgatttta
     9001 gcctgaatat cgatgctttc ttacctggcg atagtcgttt ggatgcagaa gagataaaag
     9061 ctcgcatgct tagactgctt gggcggaata accaaataaa ggctcagatt ttggtagata
     9121 attcaatagg acgagaagtc tatagagttg ctatcaacat tacagaaaca ctattttaaa
     9181 ggagacctca atggcaaaca ctaaagaagg aacaactatt gaaattacaa caggtaaacc
     9241 gattgtaggg aaaaagattt tttatttcat ccaatcagtt gacgctaaaa aagggagtaa
     9301 ggctttgctg ccagcctatc gtaccgatgg tactacaacc atgggcggtg aatacattga
     9361 tgagcaaacc caacaaggtc gcgttattga gaaggctaca gatgaacact ctattgattt
     9421 gacaacgtac tttgtaccga cagatccatc tgttgctgtc atcgaggaag ctaagaaaac
     9481 gggtaaatct atcaaaattt gggaagttat tgccgacgaa agcgtcaaag aacagatcca
     9541 aattcctgaa tcgagtggac ccaagaaaga tgtttaccct gctaagtttg ggtacgccaa
     9601 gattgacgaa atcgaacgcg gtactggtat ttcagactta gtagaaatgt cctacaccgc
     9661 taacattgta ggggccttac aagatggtaa attccctctc acgaaagaag aaattgaaat
     9721 gctagaaaat gtatacggct atcaaaatcc gggtgatact actggcgact acgataatat
     9781 cgctaggtag tacacagggg cggcaactgc tgccccattt tgatttaaaa aggagataaa
     9841 ataatggaat ttacagcagc gaaacgaaat atcgatatta aatttgattt taaaactatg
     9901 tttaagatca ataataaact aggaacaatt aacccagaaa caggagagcg caatgcagat
     9961 ggtgttggtg ctttgttttt caatatctta gagcgtaatg aaagcgccat tgtcgatctt
    10021 gtgcgtttat ctgcgggaag cggaaaaaaa gcgctaactg aagatgaaat tttagatgca
    10081 attgcggaag ctgttgatga agaaggaaca acagaagggt tgtttgctga gattgaaaaa
    10141 gaaatggttg attctggttt tttcagagcg aagattttga aatatatcga aaacatggag
    10201 aaatcagctc gctatctcaa agcgaaggac gatacggacg caactcaaat ccaaattatc
    10261 gaagacatga ttggaagaat gagcaacgca gtatcttagt aaattgcgca cggttagggc
    10321 tcacagacat tgatactatc tataaatgta ctaagtggga gctagaggct attatggagg
    10381 ggcttgagta taagcaggtt gctgagcgcg agaacctctc tgaattgtct ctaaaactta
    10441 gatatacatt aaatgctaaa aaggttgatg taggtaagct caaatacgat aagcataggc
    10501 taactatcaa aagatcgtat caaaaagcta gccgtagcca agccgatagt gatagcagta
    10561 ttgttgagag aatacaaatg cttaataatc attttcaaaa tagatagata aggaggagta
    10621 gatgccagga acatttgatg gttctatttt cgctgatgtt ggtgccaaca caaaggacta
    10681 tgagcaggcc atggctcgta ttgttagtac gactcagaat gctttcagaa aagcccaaga
    10741 tacagcggtt aacagtagta ataaaatggt tcaaatcatt ggacaaatca tggcccaatt
    10801 agcgaacaac ggcgaatcgc tcggaaagag acttggttcc gcctacgcta ctggtttaaa
    10861 actgagcatt ggtgaaattc aacgtatagc agcttccatt ggcgaaaaaa ttcccgaacc
    10921 cataaagaat gggttcaata aagctttttc aattatccaa aatagcgtac agaagttatc
    10981 tagcgccatc cctcagccca taaaatccgc attcacaagt gcaacaagtg cagtagttag
    11041 cttttcgtct aagatcacaa gtgccgtctc agcagctttc aactctgtta gttctaaagc
    11101 gaatactgtt gcagataaaa tcagtagtag ttttgggggt agaatcactt cagcggttac
    11161 taatttagcg actaagttaa gtacaggtct tagcaatggt tttagcagaa tgtctagttc
    11221 tgctgctact tccctgaatg gaatcagcca gaaattcgcc aacacctctt ctgctggaga
    11281 gagactcaaa agtacagtga tgagcatcgt gcaggccttt agtttaatgg ctgttgctca
    11341 aaaagctatg cacgctatta ctggggcaat agacggggcg gttagtcgcg ttgataccat
    11401 gaaccgcttt ccgaaaacga tggcgctgtt tgggtattct actgaacaat ctaaggcatc
    11461 aattgataag ctatcaaaag gaattgaagg cctgccaact cctctagaca gtgctgtaaa
    11521 aagtgctcaa cagctcgcca taaccacagg aagtttagat aaagggacta gtttagccct
    11581 cgccttcaat aacgcaatga tcggttacgg ggcaacaact gaaggggctg agcaagcact
    11641 caggcagttt aaccagtcgt tggggtctgg aaaaattcaa gctgaagaat ttaactctgt
    11701 atcagaagct gcgccaggtt taatgtctaa aatggcggaa gccttcggtt ttggtaaaaa
    11761 tggcgtacaa gatttaaaat cagccttatc tgatggcaaa atcactgcgc aagagttcgc
    11821 agataaaatg attgagctta acgatgccca aggcggattt gcagagatgg cccaatcatc
    11881 ggctggtgga atccgaactg catggaagaa cgtacatacc gccgttgtaa aaggcgtagc
    11941 aggtatgatt tcagcctttg atgaagcggc taaagctaat ggtatgaaga ccattgctga
    12001 aacacttctt agcctgaagc ccgcaataac cagcgttttt gatacgatta attctcttat
    12061 tccaaatgca gttgcagcat tcgctaggct aaaacagtct atcaatattg actttagccc
    12121 attaggcgcc agcgttaaag aggtgtttgc tcttattagt actgttcttg gagattttgc
    12181 acatactggt gaattatcag gacagactct tgataagtta aaagcaaaaa ttgcttcttt
    12241 agcccctaaa gtcattgccc tttgggcagt gatgaaccct gttagcgcta tagcaacgat
    12301 aatgcctttg ctttctctat tcggaaaagt tggtctagct ttaggaagct tagggacttc
    12361 tgtcggggcg tttggcggca taatttctag tgggatagct agtgccagcg gcgttgttgg
    12421 tgcctttgcg gcaactctaa gcggattacc tggcgttttt gctaccgcag cagggcgtgg
    12481 gttatctgtg cttggaacta tgacaagcgc aatgtccagt cttgtgagtt tagcactggc
    12541 ggctatagga ccggccgcta ttctaggtct tgtggtggca ggacttggtt tgattaatag
    12601 tcagtttggc gcacaaatcg accagctact taacaccgca gttacaaaag gtcctggtat
    12661 tattcaaggc cttgtaaaag ggattacttc taaaatacca gctttaatag ctagtggtac
    12721 tcaattgatt gctaagtttg caaatgctat cacagtgtta ttaccagtta taattcaagc
    12781 cggcgttcag ctaattacca gcctcgtcaa aggtatcgga caaaacgcaa caagtttaat
    12841 tagttcagca ataaaaatca ttggtagttt tgttagctca attgtgagtg ccttgccgca
    12901 acttatttct gttggaatgg agctattatt aaatgttgtc aacggcatag ttcaaaatat
    12961 acctcttatt atccagcaag cccagcaaat cattgatagt tttgggaaca gtttacaggc
    13021 taaccttcct agtattatta gcaacggtat agctattttg gtgaatcttg tacagggaat
    13081 tactcaaatg ttgccaactg ttctgcagat agctactcaa gttattacga gttttgtatc
    13141 tggaattgta cagtttttac cgcagttact tcaaggtggc attcaaatca ttattagcct
    13201 tgtgcagggg attattcaaa atatacccca gattgtacaa tctgctgtac agattataca
    13261 gtctttagtt tctggactga cgcaagctct gcctcagatt atcgcagcag gcattcagct
    13321 tgttgtacaa ctagccgtag ccttgataaa gggacttcca cagattattt ctgcgggtat
    13381 tcaattaatt atggggctcg gtaaagccat gttagaggct atcccaaatg ctctttcagg
    13441 agtttgggaa ggtattaaga gcggattcag ttcgatgtgg gatcaaatca caggtaagag
    13501 ttccacaagt acagctaaag tctctgcgga cgccacggcc atggccttga atgttggtac
    13561 tcaaacaaca gctatggcta atcaagctaa tacagatacg acatctatgc ttaatagcat
    13621 tagtcaaaat acagagcttg ctaatataaa cgctacatca aatgccacac agatggctaa
    13681 taatgttagt gctcagacag gaacgatgag tcttcagggg ttgaatgatt caatgtctct
    13741 tgcgagtggc attagcgcta atatgtctgt ggctaatatt aatgctacta ctcaggctca
    13801 agaaatggct tcaggggtta atggtgcgac ttcttcaatg aatctagacg ccattaatca
    13861 tacgctcagc ttagctagtg gtgttggtgc aaacatggga accgctagca caagtgcaac
    13921 ttctcaggcg caagctatga gctcaggagt gagtaacagt ctggcatcaa tgcagtcaaa
    13981 ctcaactaaa gcagcctctg gtctgtctaa tagcgtgaca agtgaaatgt cttctgcagc
    14041 aacctctgca acctcaagcg ccaataggtt gtcctcggcg gtcgagtctg gcttcaataa
    14101 ggcgaagact tcagcaacaa cctcaatgaa tgggatagcc aatgcggtta aaacaggatt
    14161 tagtagcatt aacagtactg caaagcaatc tatggcaaac cttgtaagtt cagtgacttc
    14221 tgggatgtct cgtgcaaccg cggtgtctaa taatgcttgt cagaagatcc tctcaatatt
    14281 cagggctttg gcagggcaga tgtcttctgc aggagcttat gcaggtcaag gttttgctaa
    14341 tggtctagct agtagcgcag gcacaatcta cgcaatagct aacagcattg ccgctaacgt
    14401 agcagcaaca attagacgcg ctctggatat tcactcgcca tctcgtgtca ctaaaacact
    14461 aggagcattt actggagagg ggtttgccct cggtatggca gagtggatag gtgagatcaa
    14521 tagtctaggt aaagcatacg caacagcagt tactgatcaa aactgggggg taaatagtac
    14581 tgtttcaaca tctgctaaag ttaataatag tggaatcaat acctctcttg ataatcttag
    14641 cgaagaggtt aggcagtctc aattgtcaga gcctatcttt gaagtgcata atgagattgt
    14701 tggagataaa atttacacgg ctgttaaaga aaaagaatca agagagcaat ctaaagattc
    14761 ttattttgtt tttgcttaga agggagtatt ttggatttat taatagaaaa agagagtcag
    14821 gcagctagat tgtctgactt tggtatttat aatattgcta ttgaagatag cgctcctcta
    14881 ctatctgtat cacaccgaac agtcaaagga aggagtggtc acatctacga tggggctact
    14941 tttacgacta aaacgcttaa ggtcaaagga agagtgacgg taggcaatgt agaaggattt
    15001 ttggacaaac aggacgaact aaacgctctg cttgttgttg acgaaccttt ctacgtgact
    15061 aagatgtacc ctgaaaactc agatctattt aactttgagc ttccagggga cagcacagga
    15121 gacctgcaac ttattggctc tcctcataaa ccttggaaat atagatttaa agtcatctta
    15181 gacgacacta tcacttatga atttgtagga aaaaccagtc aaggactaaa atataatctt
    15241 tccttcacac taagaactgc tgaattacct ttcggtgaga caaaaccaaa ggacataact
    15301 ctatcagggg gcagttttgc ctatggagga accgctaaag caagtcagtt agagtggcct
    15361 tttattatag agcttactcc ttctggaggt cagactaatt tttatattga aattgatggc
    15421 aggcgctttg agtttaagca gaatagccag ctacaaaata gtgataaatt acttttgaca
    15481 ggcatagcta ccacactaaa cggaaattat gtcaatgcta aaacgaacta tgagtatttt
    15541 atcttcaatc ctaatcctaa caagagaatt acttacaaaa cggattttct tggcacgatt
    15601 aggattttaa attttgtaga gctgtataaa taggagggtc taatgattac ttttttggat
    15661 catcgtgaca ttgagtatgg ggccattagt gtcattaggc atactaatgc tgttaatggt
    15721 gagcgctcag tgagcgggga aatttataca aacagtgatg tcctcaataa tatcgataga
    15781 gggtggcgac ttagatttga agatgagtat tacgttgtta tttacgcaaa gcctgttgat
    15841 gttggtcaaa aaacgcaggt ttcgtttgat gccatacacc aatttttttg ggacttcagc
    15901 aagagtagta tctatgaggg tctcggagat gggtctcata ccattgatac ctatctagag
    15961 acagtattta aaggtagtgg gtaccgctat aagctagaag taggtgtgaa cgcatttaga
    16021 aaacaatctt ttaattataa gtccaggtta gatttattca atgagattat taaagcgacc
    16081 ggacttgagt tttcagtcag cgggaaagtt gttcggctat taaaaaacat aggtactgat
    16141 ctgtcaacag tggtacgaaa aaatttcaac atgaatgatc ttaccattga aaaaaatatt
    16201 gatagcttta ttacctatca gaaaggcttt ggtgcatgga ccgacccaga ggactactct
    16261 aaggggagac ttgaggcgga atacgaaagt cctcttgcca aggagtacgg ccgacttgaa
    16321 ggggcgcctc tgacagatga gcgcttcacg gtggcagata atctaaaaga agctttaaaa
    16381 agtaatgttg aaaattctta taagatatca gtaaaaattg atatggaaga tttaacgaga
    16441 gctggctata ggtgtgagag gccggttgct ggtgactaca ttatggcgat aaatgagact
    16501 ttaggttttc aagagcgtat acggatagtt tcttttacaa gctactacga cgcaactgga
    16561 gctttagtaa aacatgaagt cacttgtaat gatatcggat ctgtgaaaaa acaaagcgta
    16621 ggaagtctgt ctataaacag tagaatcaat cagatagatg cagatattgc ttctgcaatt
    16681 gaagtggcaa cacaagcact agtatctgct gacgggaaaa atactgttta cggtggcaca
    16741 gaaatgccca aagatgaacc aaaaggaacc ttaaaaaaag gggacatatt atttctaaaa
    16801 gttggtgata ctactagaat gtacttttgg aatggtgctg agtgggaaga gcccgaggtt
    16861 gtgaacgacc cagaacgatg gcgtgaagac ctcgaaaaac aaatttctga ggcaatcgaa
    16921 aaagccaaaa aagcgcagga agaaatcaac caacgcaccg accaagagct tgaagagttt
    16981 agagaaacgc tcaaaaatct gtcactcccc gaagaagcca tcaaaaaaat cacagatgct
    17041 atcaaggttg atgacatccc gtcaattaaa caaagctttg atgacctaaa aaatagagtg
    17101 agtgagacaa gcgaagaatc tcgtttaact gccgaaattt tagggaacaa cggcaagact
    17161 cgttacaaca aaaatttgct ggttggcgac cctaaccgca ccaaaaccta tgatgaggat
    17221 tatatcgagg ttgaagctaa tgatggcggc tttaaacgtg gcgagacgta cacgattagc
    17281 tttagccaga cgtgtgagct gctcaaaaaa gtggctatca cgctgacaca ggctaataat
    17341 aaaggcatta aattaacgct gaccccaacc aaagccaaaa tggatgcaca gacctttgac
    17401 ctgaccaagg ataaagaggt catcagcgtc tatcctttga gctactcagc cactttaact
    17461 ggcgattggt ataaatctaa gcaagtagat ttaaatgcgt cagacacgca ggaattagct
    17521 ctgggaatgg cttataaaga tgtggttgat ggtaatagtg ctgatttagt tttgaactgg
    17581 gcggaaaacc cagatattat ttttgacgga aacggaggta tttaatgtca aaagaagttg
    17641 catcagcaag gatacagcat agaggcatgt ccacgcaaga gtgggaatca agttctgata
    17701 ttttaatgga gcgagaaatt ggaattgaca tgactacggg ttacccaaaa gttggtgatg
    17761 gtaaaagccg atttagtgag ctaaacgact tgcgtggtcc tatggggcct caaggtccta
    17821 gaggagaaag aggcccaatt ggcccaacgg gtccgattgg caagactggt gagacaggtc
    17881 ctcaaggtcc acctggcccc gctggagcaa caggtcctaa aggtgctgac ggtaaaatga
    17941 cctttgagca actcactaaa gagcaacgtg agcaattaaa aggtgataaa ggagaccctg
    18001 gcccaagagg agctgatggt cagcgtgggg aaacgggtcc tattggccca ccaggaaaag
    18061 atgcggtttt gcccgacgat gttgtccgta agccagattt aacagcttac gcaacaaaag
    18121 acgagcttaa aaagatatcg gttggtcaag ctatacctgt ttttaccact agctaccagt
    18181 acgacagtgg ctacctcaag tactatagtg acagctatcg agccacttgg tcagtcaatg
    18241 aggatgcaag caagttgctg gctggtgata ttgtggcgct cgaaataacc aatacgagcg
    18301 agagagccaa aaactacctt atcgtgtctg ttgtgtcatc gtcgaggtca agcatcacgt
    18361 caatcagtcg agagctatct aaggataagc cagaaggcac aacgtttttg actcaaaaag
    18421 acgcagataa aatctatgct actaaacaac ataagcacga gattgacgac atcaacggct
    18481 tacagagtgc tttaagtcat aaagccaatg ctcaacatag tcatagcgag tacttagagc
    18541 aatcaacagc tgacagtctt tatcttgcta aacacgagat tgagggatat ttgtctagct
    18601 acgtcagaca agctgagata cgatcgctga ttgacaatat cggcaagcta aaagatgaga
    18661 cgacaggtca gtacctatct gtaaaagtcg ttgataaagg caatgtgcct tatgacacca
    18721 gcggcatgat tgtttttgag agggcttagc gatggcaatg caagagatta aagatacttt
    18781 tttttataaa atcgatggtc aaaccatagg ttacagcttg cttcaaaagt ctggcttatc
    18841 tcttgggcaa ttttatatta aaatctctga tcgatataat tttaacgcag gcagagatgt
    18901 cgatatttac aaaattatat ccagtacaca agctgatgtg tataaagcaa ataagtataa
    18961 ttatcagtcg ttgtcagaga cagagcttag cgcaccgcag ccaccaactt cgccgccagc
    19021 acccaaaaac gacagtttgt atcaatcaat cacgattgac ggacgggcaa ttggtcgtgt
    19081 catttgtaac aatcaagtag tttggcaaaa gcaaggtcgt agcacaagtg ctagcggtgg
    19141 gtggcagcag ttatggcaag gtaacttatc tttagacgat gttagattgc ctggctatca
    19201 gatttacttt tttaaatctg actacgatag ttttatcagg tccgcaaccg atttaatcgg
    19261 ctcttatgag tcaattaatg gtaatacttt aattgcccga tacgaccaca gtaacaacca
    19321 attgctcgtc agtggctttg gtcaaaatcc agtcacgatt tacggtaaaa actaggaggt
    19381 aacaattgag cagagatcca acacttattt tagacgagtc aaacctcgtc atcggtaaag
    19441 atggacgtgc ttattataca tttacggcta gtcaagacaa tcaaaaagtc agactagcta
    19501 gtgattgttt aggcacagcg cactttaatc aggttatgat tgagcgaggg gataagccaa
    19561 ctaattacgt tgcgcctgtt gtaattgagg gtagcggagt tgagacagga ctttttaaag
    19621 accttaaaga aattagcctc gagctgacag acaccgaaaa ttctaacttg tggtcaaaaa
    19681 tcaagcttaa caatcgtggg atgttacaga catactttga cacgactatt aaaaacgaga
    19741 ttttaacaac agctcaaggt atcagagaga ctatatccga caccgagcga ggacttaaaa
    19801 gcgagttttt aaaaacggta caaggtcagc gtatccagct tgagagcttg ctagagcaaa
    19861 agaccgctca actcggcttg acggtcgatg gtctaagact tgatttaaac aaagctgaca
    19921 agcagacagc tagtttacag gctagtatcg agggattgag acaagattat aaagacgctg
    19981 atagacagct atcaggtagt tatcagtctg gcattgaggg actaaaagct caactagcca
    20041 atgataaact cggtttacaa gctgagatca aagcatccgc tcaaggacta tcacaaaagt
    20101 atgatgacga gctgcgcaag ctatctgcta agatcaccac aacctcatca ggcaccacag
    20161 aggcctatga gagtaaatta gagggcttac gtgctgagtt tacacgtagc aatcaaggca
    20221 tgcggacaga gcttgagtca caaatcagcg gattaaaagc cgtgcagcaa tccacagcta
    20281 gtcaaatctc gcaagagatt agagatcgta caggagctgt tagtcgtgtg caacaggact
    20341 tagctagcta tcaaagacga ttacagtctg cagagggtaa ttactctagc ttacaacaga
    20401 ccgtcagcgg tctacaaagc gatgtccgct caccaacagg taaaatccaa tcacgcctta
    20461 ctcagctaca aagccaaatt gaccaacggg tgacccgtga tggcgttatg tccatcatca
    20521 atcaatctgg agacagtatc aagctagcta tccaaaaggc tggtgggatt gatgccaaga
    20581 tgtccgcaag tgagattatc tcagcaatca acctaaatgg ctacggtgtc agaatttctg
    20641 gcgagcgtat tgctttagac ggtaatacga ccgttaacgg ggcatttgga gctaagcttg
    20701 gtgagtttat caagcttaga gctgataaca tcatcggcgg cacgattgac gctaataaaa
    20761 tcaatgtgat taatatcaac gctagcagta ttgttggttt agacgctaac tttatcaagg
    20821 ctaaaatcga gtatgcgatt actagtttgc ttgagggtaa agtcatcaga gcaagaaatg
    20881 gtgctatgag cattgacttg cagacaggcc aaattaatca ttatacagat acatcagcaa
    20941 tgagacgtat cgatagtagc acagctagtc aatttataaa gatgacaaaa tctggttttg
    21001 tgtctgaaat aggacgtaca caagcagcaa tgacggttat aggctcgaac agtgatggct
    21061 cggaaagtca tgacaatgct ggttttgctg gcatgagaac ttggaacggg actgtaggat
    21121 atcaatccac aagcttgatt gagttggtcg gtaatcgtgt cacaatttat agcaataaaa
    21181 accgtagtcc atggcttttt gactccacga caccaggata tgcttaccta attccgcaaa
    21241 acgacaatgg cacaaaacac atgattggtc gagcagaccg caaaatagac caaatttacg
    21301 taggggatat ttttgttcaa ggcgagcgtg tcgctatgat gttaaaagat ttagcaaaca
    21361 gaataggttt ttatggcggc tgggctagtc gtataggata aacaggagat aacatgcaat
    21421 taaccattaa aaacaaagat ttaaacacgc tacatagcgt acttgataaa atcaaggtca
    21481 caaacatgcg ggcgaaccgt gggcgtgcta agctgcttgc caaagttgag gcaaagctaa
    21541 gcgagtatgc taaagatgag gttgatatta ttgaccagta cgttgccaaa aatgatgatg
    21601 gcaagtggat tacagatgac aaaggcaatc caaaaatcga tgacacgtca aaactagctg
    21661 agcttaacga ctttttagac gagttggcaa gtgagcctat catcatcaaa ggtggtgaat
    21721 attctaagcg atttatcgat tttttggaat acttggcaga atcggaagac gaatttacat
    21781 cagaggaaat cgtcttaatt gataacattt tggaacaatt tgaagaaagc aaaggagaat
    21841 aactatgcgt aattggaaag taacaggaaa atacccacaa tacgatagcg caggagcagt
    21901 cgcaagcact cacgttatta tcgccgctga ggatggagct gtcatcccac aattggttaa
    21961 gcgagatcta acaggcacaa acgacaagga catcatcgca gcggtgcttg aagaatttaa
    22021 aaaatcagaa tacgtggaaa ttgctatggg cgaagccgtg caaaaagtcg atgatcttga
    22081 aaaattatcg caggaaactg ccaagactgc taaaacagcc caaacagccg caggactagc
    22141 taaagtgtcc gcagagcgca cgcaaaagat gatcaacttg cagactatcc acgttttgac
    22201 aaccagcgat aaagtcgagc ctgatattta taaaggcatg cttgagctaa tcgagccagc
    22261 caaaaaaggt gagtatcaag cttatgacgt gtttacggtg gtcgacgagt cacatgagga
    22321 gcaagccggt gaaggcaacc ttgtctttgt acacgttaac gagccgttta cttatgaggc
    22381 gcaaaccctt aaagagctaa aagagctaga ggaagagggt aaagtcacag ttatcaaata
    22441 tgcggatttg gttaaacaag attagaggtg gttagatgca cgaaatctta atacaaatca
    22501 aagagttagc gggggcagta agtgcccttg ccctcattgg tggtgctatg atttggattt
    22561 acaaaaagct tgttattgag ccagatagca gactagcaaa aagattgcag gtggaaaata
    22621 ataagttgct gacggacacg gtaaatcctc tgactgatgc catcaaagac cttaattata
    22681 atctcaacac tgccacaaaa gagagagctg agatgcgcaa ggatattgaa gtacatgaag
    22741 gaagacttga tgcccacgac atccgactaa ctgttttaga gacaaaggag aaataaaatg
    22801 caagaaatta ctaatattat tacaggatca tcactatcaa ttttgactat tttggcaggt
    22861 attgtggtta aacttgttaa agattatcta ctaaaaaaag gtggagaaaa agcggttaaa
    22921 atcgctgaaa ttgttgctcg caacgctgtt gaagccgttg agcaaatcgc ttatgacaaa
    22981 gacatcaaag gtatcgaaaa actaacagaa gctaaggttg cggttcgtga cgaattatca
    23041 aaacataatg tctatttgtc tgagaagcaa atggaagtct ttattgaagc tgctgtaaaa
    23101 cgaatgaatg ataactggaa aggtcaataa tatggcaact ttagatgaag tcttgtcttt
    23161 tgcaaaagga ttagcagatg ctggccaagg ggttgacctc gataatgttt acggtacgca
    23221 gtgcgtggac ttgcctaact ggatcacgac aaaatatttc ggcattgccc tttggggaaa
    23281 tgctattgac ttactagata gtgcagccgc ccaaggaatg gaagtggtct acaatgctcc
    23341 aggcgtgaat ccaagggcag gagctatctt tgtgatggta acttacgctc acggctatgg
    23401 tcatacagga ttagtcattg ttacatcaga cggatatgtt ctgcataaca tcgagcaaaa
    23461 cgtggatggt aatgcagatg ccctttatat tggtggacca gcacgttatg ttgaccgccc
    23521 atttgaagat ggcactggat atatcttagg ttggttttac cccccttacg atagtacgcc
    23581 agcagcagcg acagagccaa gtgctccagt ggttgcacag tcagatggta cttatatagc
    23641 taaccctgaa acaggtactt ttaccgttcg tgttgctgct ttaaacgtcc gctctgcccc
    23701 tcgattagat gcagaaattg tggcgactta tggtgaaaac atggaattta actatgatgg
    23761 ttggattgac tcagacggct atatttgggt gacatatatc agcgcaacag gcgttagacg
    23821 atatgtagca gtcggtaact cacaaaatgg cagacgtgtg actaactttg gtacttttag
    23881 ataggagata aagctccgag ataagacaaa tgccctcagc aatcgctggg ggctgttttg
    23941 ttattaatag tgaatgcaac aaaattttta caatatattg tgttaaaaaa tgtattttta
    24001 tatacaatca ttcaatatgt tgtgttcgct tgaatttata agtttcaaga cacgatcttg
    24061 tgtcttgaca ttattttaaa aaaaagtata attatcttaa caagacaaac cccccattcc
    24121 tttaaaggca gatacgttct gatatggggc tttttttata tcgttaggag agttatgaaa
    24181 caacctttag ctttgacatg ggaagatcaa attaggttat ttgaaaaacg tggattaatt
    24241 gttaaagctg atgatgtaga gaaaatcaaa cacatcagtt attatagaat taaagaattt
    24301 gcaaaaccac ttgaaataaa gcgacaagat ggtgaggaga aagatatttt atatgataat
    24361 attgagtttg cagaagtttt ggcaagatat tatcaggata aaaacttaag aatctatcta
    24421 ctgcacgcta ttgaaaaaat tgaagtggct attaaaacaa aaatttcttt tgttttgggg
    24481 gatagatacg gagcatttgg atatttaaat ttctcttcat ggg
//
LOCUS       DARYSY010000031        24223 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYSY010000031 DARYSY010000000
VERSION     DARYSY010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24223
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(226..498)
                     /locus_tag="TVR04_001165"
     CDS             complement(226..498)
                     /locus_tag="TVR04_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1269862.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(515..1891)
                     /gene="dnaB"
                     /locus_tag="TVR04_001166"
     CDS             complement(515..1891)
                     /gene="dnaB"
                     /locus_tag="TVR04_001166"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1269863.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKENDSTEEVLEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(1912..2364)
                     /gene="rplI"
                     /locus_tag="TVR04_001167"
     CDS             complement(1912..2364)
                     /gene="rplI"
                     /locus_tag="TVR04_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1269864.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAREASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVIAEIKLNIAEA"
     gene            complement(2361..4337)
                     /locus_tag="TVR04_001168"
     CDS             complement(2361..4337)
                     /locus_tag="TVR04_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1269865.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAKFMESKQVFY
                     RRVNMDRFYFFTDYKILKELMDDKFSILEQFRKEAQEAQLPLTLSMGISYGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIIVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISAIDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTMLSMAYIEASFVIVETGADKIAISARSRSKINVQRIMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(4425..6323)
                     /gene="mnmG"
                     /locus_tag="TVR04_001169"
     CDS             complement(4425..6323)
                     /gene="mnmG"
                     /locus_tag="TVR04_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1269866.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGKVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKRLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQTSHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKPLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEELDAKMIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(6326..6790)
                     /locus_tag="TVR04_001170"
     CDS             complement(6326..6790)
                     /locus_tag="TVR04_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1269867.1"
                     /translation="MVQDFRTRTADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAIKREVLEEVGAEVSVDHLAFVVENQFCLEGVNFHQIEFHYIVSLLSDP
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(6995..8119)
                     /gene="mnmA"
                     /locus_tag="TVR04_001171"
     CDS             complement(6995..8119)
                     /gene="mnmA"
                     /locus_tag="TVR04_001171"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1269868.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGIVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFIGEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            8402..9073
                     /gene="sdaAB"
                     /locus_tag="TVR04_001172"
     CDS             8402..9073
                     /gene="sdaAB"
                     /locus_tag="TVR04_001172"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1269869.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQAAVKQIATIPNLHN
                     VNFFD"
     gene            9085..9957
                     /gene="sdaAA"
                     /locus_tag="TVR04_001173"
     CDS             9085..9957
                     /gene="sdaAA"
                     /locus_tag="TVR04_001173"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1269870.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALADIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            9991..10626
                     /locus_tag="TVR04_001174"
     CDS             9991..10626
                     /locus_tag="TVR04_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1269871.1"
                     /translation="MKAILFDLDGTLVNSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEVTFSAFFKDQHDVELAITHFRDFYKESGIYQARLYPEITELLDTLSQKNLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSIPNRCHKLDIIKACLQDFAINQKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(10687..11298)
                     /locus_tag="TVR04_001175"
     CDS             complement(10687..11298)
                     /locus_tag="TVR04_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1269872.1"
                     /translation="MFKQDILKQRYVSFGIVAAAIALLAVVFAFSSENVNTDSYAKSS
                     DSKVVKKKDKTKKSTVAKSATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(11553..12362)
                     /locus_tag="TVR04_001176"
     CDS             complement(11553..12362)
                     /locus_tag="TVR04_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1269873.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDSLAIALVVILGIFLFYLKSPSGLT"
     gene            complement(12355..13197)
                     /locus_tag="TVR04_001177"
     CDS             complement(12355..13197)
                     /locus_tag="TVR04_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1269874.1"
                     /translation="MSIHFQDVSYTYQAGTPFEGRALFDVNLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTSGKVTVAGKAITNQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEDLFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVADYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQCLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(13173..14012)
                     /locus_tag="TVR04_001178"
     CDS             complement(13173..14012)
                     /locus_tag="TVR04_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1269875.1"
                     /translation="MSNIIEVKNLTFRYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEENVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIDRVYQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKEDGFPIQGAYLTEKELEEQLCQFI
                     SKM"
     gene            complement(14015..14557)
                     /gene="pgsA"
                     /locus_tag="TVR04_001179"
     CDS             complement(14015..14557)
                     /gene="pgsA"
                     /locus_tag="TVR04_001179"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1269876.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARQWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGGEVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(14570..15574)
                     /locus_tag="TVR04_001180"
     CDS             complement(14570..15574)
                     /locus_tag="TVR04_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1269877.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(15624..16907)
                     /locus_tag="TVR04_001181"
     CDS             complement(15624..16907)
                     /locus_tag="TVR04_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1269878.1"
                     /translation="MTPLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     HFGSLDTSFTVGCQRVNLPPGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYHPVIKSRSIDMDVASAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAMLLGWTSKAYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDINEEHLELVKKEIYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(16909..18153)
                     /locus_tag="TVR04_001182"
     CDS             complement(16909..18153)
                     /locus_tag="TVR04_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1269879.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSTLKTKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRTYIDPSYTLSSWIDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            18368..18781
                     /gene="yaaA"
                     /locus_tag="TVR04_001183"
     CDS             18368..18781
                     /gene="yaaA"
                     /locus_tag="TVR04_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1269880.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            18783..19892
                     /gene="recF"
                     /locus_tag="TVR04_001184"
     CDS             18783..19892
                     /gene="recF"
                     /locus_tag="TVR04_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1269881.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPSLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDSDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEASKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMDQLKATHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNIRQTKLLEAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIALDSVMID"
     gene            complement(19956..20819)
                     /locus_tag="TVR04_001185"
     CDS             complement(19956..20819)
                     /locus_tag="TVR04_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1269882.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTLGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGVIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(20990..23416)
                     /locus_tag="TVR04_001186"
     CDS             complement(20990..23416)
                     /locus_tag="TVR04_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1269883.1"
                     /translation="MIFTDEQRKEIAAEGYEEHTVGSPVIVKDSNSKFFIGYVSQIED
                     SISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGND
                     LPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVTS
                     VSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKHLHDRIYNYVDPHDIIGMGFDQKEG
                     AVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPVDIDSDNRLD
                     TKVEELYLGFRNYFDASTSARYGVLSDKQTIVINAGVLTNLAQNLQSSILGDLQTIRY
                     ITEKCQAKNDVIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLFD
                     MLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWIDS
                     IIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKADGISDSLKEVFRVELQDII
                     ELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTGL
                     LDDVRDILQAFDEQMEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNTFKDIVTVL
                     DRRFSDRVYVERTEIKDETSITTRDYWGNLGTLYPYRIRSGIASARVEVCPLVPALTD
                     TIQRVNTARHRLQNLHRDLSRLIEKGVYSALDLDGIITSQKMVGRLLDKIIVELSFVK
                     ATIEVSMSGKAASAMVSHLALLLKRLGYFSQLVADCFGTHVTKVPNKAPVRASHQAKR
                     FSLNNPLALQ"
     gene            complement(23400..23819)
                     /locus_tag="TVR04_001187"
     CDS             complement(23400..23819)
                     /locus_tag="TVR04_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1269884.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYNQIKQVELKNAHSK
                     EAIDIYEKELTSIDPQALTIEGLIKSYTIDSDSLFINPMGGFSIHLIINNDPDTYLRV
                     RLDRRNWERDLEIASIYYSEKLEKLLEKEGLIDDFYR"
     gene            complement(23816..24217)
                     /locus_tag="TVR04_001188"
     CDS             complement(23816..24217)
                     /locus_tag="TVR04_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1269885.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIHLIINDDPDTYLRV
                     SFGRYDWERNLEIDGIYRSEKLEKLLKGVEK"
BASE COUNT         7316 a         5303 c         4425 g         7179 t
ORIGIN      
        1 gtatcatcaa aaatggttag ctgtaaactc aaagattggg acctagtacc aagaacttca
       61 gagtagctgc ttttcaagaa agctagtccc tattattaac caggacttta ttagccagga
      121 cttcagccat ttgccaatag gtcctcctag gctgcaaatt gattgacacc tttacaaaac
      181 tgtcaatgaa gtgtaaagaa aaagccctaa atgggcattg atttttcaat caaaataacg
      241 aatcagtgtt ttttccgtca aaatatctga ataggtataa gactcaacat aagaattatt
      301 cgcttcccct gaagcatctg ggttcccctg atactcaatg ataaataaag aagggtaaac
      361 ctctatcaat ctgccaacct tatttttttc acgcttacga ccattttcaa gtgttaactc
      421 aaccaactga ccttcatgag ccttaatgtc ttcctttatt tttttcattt tggcaacatc
      481 tgtaaatgca tcactcattc tctttccctc tttcttatct ttcctcaaat tgagctattg
      541 tcgaaaattt attgtattcc ttttgaaaca tcagcttaac tgtcccacgc gcacctgccc
      601 tgtttttctc aagaatcacc tcaattgtat tatcctcaag gacttcctct gtgctgtcat
      661 tttctttacg ataataatcg tctcggtaca aaaatgcaac aatatctgca tcctgctcaa
      721 tagagccaga ctcacgaata tcagatagaa ctggacgctt gtcctgcctt tgctcaacac
      781 cacgagaaag ctgactcaaa gcaataacag gcacctttaa ttccttagct aaaatcttca
      841 gctgcctcga aatatcagaa acctcttgct gacgattttc aggtcttgta ccagtgatca
      901 gttggagata atcaatgaca atcagcccta aacctccctc aacctcctga gacaatttac
      961 gtgccctagc tctaatttca gtgatcttaa tgccaggtgt atcatcaata tagatgggtg
     1021 cctctgctaa agctccctga gcaatggtta cattattcca atcctggtca gtcaattgac
     1081 cagttctcaa gctatgtgaa ttgaccattc cttcagctgc cagcatacga tcaacaaggc
     1141 tttcagctcc catttctaag gagaaaatgg caactgctct cttttgcttt gtaccaacat
     1201 tttgagcaat gtttaagaca aaggctgtct taccgaccgc aggacgggct gctaaaataa
     1261 tcagttgatc tgggtgtaaa cctgttgtaa tcttgtcaag atccctaaag cctgttggta
     1321 aacctgtaac gtctgatgtc tgcttagaac gaacctcgag attctcataa ttaatcttta
     1381 aaacatctga aatcttacga aagccactac gattactatg ctcactgata tcaaccaaag
     1441 ccttttcggc acttgcaata atatcctccg agtcagatgc gccctcatag gctaggttta
     1501 cagtctctgt caacctattg ataatgtcac gcagcatagc cttttcagct actattttag
     1561 catagtattc tgcattggca ctggtaggta cactattaac cagctcaaca atataagaca
     1621 agccaccaat atgttgaagg tctccttgat catcaagaat cgtcctcact gttgttgcat
     1681 caatagcatc atttcgatca ctaagcctta tcattgccct gaaaatgacc ttatgagaat
     1741 acttataaaa atcctctgga ccgataaatt ctctaacggt aatcaacttg tctggcgaaa
     1801 taaagataga gcctagtaca gactgctcgg ccagtaaatc ttggggttga actcgtaact
     1861 cagcaacttc aggcaaactc agcacctcca aatctttttt aggctgatgt gctatgcctc
     1921 agcaatgttt agctttattt cagctatcac ttctttatgc agcttaactg gcacctcgat
     1981 aagaccaata gcacgaatag ggtgatctaa aacaatatga cgcttgtcaa ccttgacctt
     2041 aaattgcttt tgcaattcct cggaaatttt cttggctgta attgagccaa aggtacgccc
     2101 atctggtcca accttttcct taaactgaac acgagtcttt tcgtcatcta ggattttctt
     2161 aacagcctta gcctctgcta ggatttcagc ctgtgccttt tcctcagctt tttgttgccc
     2221 tcttagctgg ccaattgctt gactgctagc ttcccttgct agatttttct taatcagaaa
     2281 attctgagcg tagccagtgg gaacctcctt gatttctcct ttttttcctt ttcctttaac
     2341 gtcaactaaa aaaatgactt tcatgactct acctctcttg tttctttcat tgtgttatca
     2401 attgtttcta gtaacagctg cttagcctcg ctaagactga tatgcttcat ctgacacgct
     2461 gctaagttga aatgtcctcc gccaccaagc ttctccatta ttctttggac attgatttta
     2521 ctacgacttc ttgctgatat agcaatctta tcagctcctg tctctacaat aacaaagcta
     2581 gcctcaatat aggccattga tagcatagta tctgctgcct tactagcaat aacattacta
     2641 taatattgcc cagcaagccc agttgcaacg ataatggagt cgctaaggcg ctcacctctg
     2701 agaatgatct cattaacctg cttatagtca tcaaaatcaa ttgctgaaat attttgaatt
     2761 tcgacgctat cactacctct gcttcgtaaa taactagcaa catcaaaggt tctactggtg
     2821 acacgtgttg aaaaattctt agtatccagc ataataccag ccatcaaaac acttgcttga
     2881 atcttgttta agcgcttctt cgcattttga aactggatta attctgtcac tagctctgcg
     2941 gcactgcttg caccactttc aataaaggtc aagatagcat tatctggaaa atcatcatct
     3001 cttcggtgat gatcaacgat aataacatct tggaattgct cgtaaaattc cttagacaag
     3061 gttaaggaaa tcttagagtg gtccaccatt actaacagtg atctaggggt cgtaagcccc
     3121 attgcttgag aaacactgat aagacgtgtc ttaccatcag cctgtaagcg ctcgatagct
     3181 ctttcaatgt ctggactcat ctcatcagga ttatagacag caaagctgtt ttcaataatg
     3241 ttactagcaa aaaattgcat accgacagcc gagcctaagg cgtccatgtc cagtttacgg
     3301 tgacctacga taaacacatt atcaaccatt ttgatacggt ctgaaatagc tgtcatcatg
     3361 gcacgcgtcc tagtcctaga gcgtttaacc gtagaaacag agccgccacc aaaatagacc
     3421 ggatttgtgt ggtctgcatt ttcacgaata acaatctgat ctccgcctcg gacaagagca
     3481 atattcagat tctcaagagc aacctgacca atttgacaat gattttcctc tccataggaa
     3541 atacccatgc ttagggtcaa tggtagctgc gcttcttggg cttccttccg aaactgctct
     3601 aaaatagaga acttatcgtc catcagctct tttaagatct tatagtctgt aaaaaagtaa
     3661 aaacgatcca tattaacacg tcgataaaat acctgcttag attccataaa cttagctatg
     3721 aaattagcca caaatgaatt tatctttgac gtatcagcat cagataggtc atctgtaatg
     3781 tcgtcataat tatctacaga aataatacca ataactggct ttagcaagct agaatctgct
     3841 gattgtctac taccaacaga gctatcaaaa aagtaaaaaa tacctgatgc cacatcaata
     3901 taagacgtgt atcgattgcc agaaacctca aaggtttgag aaatatcact tttacgctta
     3961 tcagtgagaa gctgttggat catctgttcc tgtaaaaaac cggcctcatc agtgaaaatc
     4021 agctctgcgt aaggattgta ccattcaata gcattggttt cttgatcaaa ctgaataaca
     4081 ccaactggca tgttatccag taacgttttt aaattatttt ctgtttgttc gttcaatagc
     4141 tcaatgtggt ctaaatcaga caattcgtaa accttttttt gataccaaag caaggccgca
     4201 acaaacaaca acactaaaaa aatagctagt gtaatcagca tttttgattg catgattcta
     4261 acacataagg ctagtaagcc gaataaaatc aactccatca taattaaatg aatggtttca
     4321 aaacgaaatc ttttcatctt taacctctta atcccgtatt ataccataaa acagccctga
     4381 aatacagagc tgtcagtggt tttgagatta caatttgatg actattatgt tttacggcga
     4441 gcctttccat taccttcaag gtaaaccatt aaaatgctaa tatctgccgg atttacacct
     4501 gaaatgcgac tagcctgacc aatggtttct ggattgattt tcttaaattt ttgccttgcc
     4561 tcagtagcaa ttgagtcgat agcgtcccaa tcaatggtct taggaatccg cttttcctcc
     4621 atacgcttca tcttagcaac ctgatcaagg gcctttttga tatagccctc atacttgatc
     4681 tcagtttcta gcagctcaat catcttagca tctaattcct cagcagcagg acctataaat
     4741 gacactacag tggcatagtc aacctctggt cgacgcataa attccttagc tgtcattgcg
     4801 tctgtcaagg gcttaaagcc aagcttttga acacgagcat tggtttcttt gatcggcttt
     4861 aatttgatac tatctaaccg ctttaattca ttatcaaatt gatttttctt gatttcaaag
     4921 gcagaccaac gttcatcgtc aaccaagcca atctgacgac caatttcagt caatcgcatg
     4981 tccgcattat catgacgaag gataagacga tattctgcgc gtgatgtcag caaacggtaa
     5041 ggctccagag ttcctttggt taccaaatca tcaatcatta caccaatata agcgtcgctg
     5101 cgctttaaaa tgagctcagg cttaccctga accttcaaag cagcattgat accagcgaca
     5161 aggccttgac cagcagcttc ctcatagcct gaggttccat tagtctgtcc ggcagtaaaa
     5221 agccctgaaa tcatctttgt ttcaagggta gcgcgaagct gatgaggtaa tacaatgtca
     5281 tactcaatag catagcctgt tctcatcatc tcagcatttt caagcccctt aatagagtga
     5341 accaattcct tttggacgtc ctcaggaaga cttgtggata gaccttgaac atagacctcc
     5401 tcagtgtcaa agccttctgg ttctaaaaag agctgatgac gctctttatc agcaaatcgt
     5461 acaatcttat cctcaattga tggacaatag cgtgggccca ctcctttgac gactcctgaa
     5521 aacataggtg ctcgatatag gtttttagtg atgatatcat gactggtctg attagtgtag
     5581 gtcagccagc aaggaatctg attagccaaa taatctttgt ccttagacat aaaggaaaaa
     5641 tgatttggag tcacatcacc aggctgaatc tctgtcacct cataatcaat agaagaagcc
     5701 ttgacacgtg gtggggttcc tgtcttaaag cggccaattt caagaccaag ccttttcaaa
     5761 ttatcagcta gtgtcactga ggccaggctg ttattcgggc cagacgaata tttcaattct
     5821 ccaaggataa tctcaccacg aagagctgta cctgttgtta tgatcactgc ctgagctgca
     5881 tatttttgtc ctgttgctgt cagcactcca acaaccttac cattttccac tagaatatca
     5941 tcaatcatag actggcgaag agtgaggttt tcttgctttt caacagtatg cttcatctca
     6001 cgtgcataca agcttttatc cgcttgagct cgtaatgctc gaactgccgg tcccttacct
     6061 gtattgagca ttttcatttg gatataggtt ttgtcaatgt ttttccccat ctctccacca
     6121 agagcatcaa tttcgcgaac aacaataccc ttagctgacc ctccaataga gggattgcat
     6181 ggcataaaag ccagcatatc aagatttatc gttgctaata aggttttaca ccccatacgg
     6241 ctagccgcta agctggcttc aacacctgca tgtcctgctc ctacaacgat gacatcgtag
     6301 gattctgtaa attcatgtac catatctact cctttatctc aatatgtttt atatgctgag
     6361 gctgcctgtc ccaatgcttt atagcccttt ttaaacaact aggattgagc cttatcttat
     6421 ctagatcatc aagagcaacc cactcacaaa ccctagtaca atcaccctca actacagaag
     6481 ggctaggatc agataataga cttacaatat agtgaaactc aatctgatga aagttcactc
     6541 cctctagaca aaattgattt tcaaccacaa aggctaagtg atcaactgaa acctcagctc
     6601 ctacctcttc tagaacctca cgcttgatag cttcttctgt gctttctcca acatgaatag
     6661 caccacccaa aagataatag tcctctttgg gtgatttagc aagataaata tagccgtctt
     6721 taattattaa cgctgaagcc ctgacaccaa agctatggtc tgctgtcctt gttctaaaat
     6781 cctgaaccat cttttctcct tgacactgtt tttaagctat aaaaatagtc aaaacctgag
     6841 aaagctgtaa gccaaaaaga cttacaattc ccatgagctt tgaccatcat cgttattgtt
     6901 aaccttattc tatcaaaatc tgctagcttg tcaagactta tcaaatgaca aagtcgtcaa
     6961 ctttattgac acatctgtca attaacatgt caagctaaat atattgacaa ggctcgccat
     7021 ctttatacgc catatcaata ataccaccac caagacactc atgaccatca taaaaaacga
     7081 ctgcttgacc aggtgtaatc gcacgctgag gctcagcaaa aacaacctta gctttgtctt
     7141 tcttgacatg aaccgtcacc ttagaatctg gctgacgata gcggaacttt gctgtgcatt
     7201 ctaaggtgaa ttcttcagga acttctcttg taaactgaat gacagaagcg tcaagactag
     7261 ttgacattaa ggactcgtgg taaaagcctt gaccaacata aaggatattt tgtgaaaggt
     7321 cttttccaac aacaaaccaa ggcttgttat ctccaccctg ctgaccacca atgccaagtc
     7381 ccccacgttg gccaatagta taatacatca agcctgcatg ctctcccata tcacgaccat
     7441 caacagtcat catacgcccc ttttgagctg gtaaatagtg gctaagaaag gtcttaaaat
     7501 tcttctcacc aataaaacaa atccctgttg agtctttttt ctttgctgtt gcaaggcctg
     7561 cttgttcagc aatagcacgt acctctgatt tttgcaggtg acccaaggga aacatggttt
     7621 tttggagctg ctcttgtgat aattggctta aaaaataggt ttggtccttg cccttatcaa
     7681 gaccacgcag catatggact ataccatttt catcacgttt gatttgggca tagtgacctg
     7741 ttgccacata atcagcaccc aatgtcatcg cataatcaag gaaggcttta aattttatct
     7801 ccttattgca catgacatca ggatttgggg tgcgtcctga acggtattct gctaggaaat
     7861 actcaaatac cctatcccaa tattcttttt caaaattaac agaatagtaa ggaataccaa
     7921 tctgatcggc tacggctgcc acatctttat aatcctcagt cgccgtacaa acaccaaatt
     7981 catctgtatc gtcccaattc ttcataaaga cgccaattac atcatatccc tgctccttta
     8041 acagcaaggc agttacagat gaatcaacac cgccactcat gccaacaaca acacgtgttt
     8101 tcgagttatc tgtcatcatt tattctccca tcaatataag atacaaggac atgagaaaaa
     8161 agaatagaac gaatcaactt gcctaaacaa ggctctagca aatggttcgt ttctacattt
     8221 tttgtctttg tccaagtgtt ttctcaaagc tcgatttgaa ggtcgatttt gaagcgccgc
     8281 tagacgcatg actattataa cagtattgtc tcttatttcc aacaatatct tttttcataa
     8341 caaacgacat ttgattagcg atttgttata ataaaaagga taaaaagagc atggagcata
     8401 tatgaacaca caaaaatttc aatccgtttt tgacatcatt ggaccagtga tgattggacc
     8461 atcgagcagt cataccgctg gtgctgttag aatcggaaag gttgtccact ccatttttgg
     8521 agaaattcct gatgaggtga cctttcatct atacaattca tttgctaaga cctatcaagg
     8581 ccatggtacc gacaaggcac tagtagctgg tattatgggc atggatacgg ataatccaaa
     8641 catcaagaat tctcttgaaa ttgctcatca aaagggcatt aaaatttatt gggatatttt
     8701 aaaggatagc aatgctcccc acccaaatac tgtaaagatt agtgtcaaaa aggctgataa
     8761 agcaatgagc attacaggtg tgtcaattgg aggaggaaac attcaggtca cagagctaaa
     8821 tggtttttct gtttccttgt ctatgaatac tccaacctta attattgtcc atcaagatat
     8881 tcccggaatg attgctaagg ttacagatat attgtcagct agtgatatta atatcgctca
     8941 aatgactgtg actcgtgaaa gtgcaggtga gaaagccatt atgattattg aggttgattc
     9001 tcgtgactgt caagctgctg tcaagcagat tgcaactatt cctaatctgc ataatgtcaa
     9061 tttctttgac tagaaaggta tgccatgttt tacacaattg aagagcttgt caagcaagct
     9121 gatgatagat ttgatggtaa tgtagcagag ctaatgattg ctacagaggt tgaaatgact
     9181 ggtcgaagca gggcagaaat tctatccatc atgtcacagc atttacaggt aatgaaggat
     9241 tctgttgtca gcggattgac agcaaccaaa tctattagcg gcttaactgg cggtgatgct
     9301 cttaagatgg atcattacat caaaaaagga aaggggcttt cagatcaaac cattttaaca
     9361 gctgtgagaa atgctatggc tgtcaatgag ctaaatgcaa aaatgggact tgtttgtgca
     9421 acaccgactg ctggaagtgc gggctgtcta cctgcagtcc ttgctgttgc tattgataag
     9481 ctcaagctat cagaaaagga gcagctggac tttctcttta cagccggtgc ctttggctta
     9541 gtcattggaa ataatgcctc tatctctgga gcagaaggag gctgtcaagc cgaggtgggc
     9601 tctgcctctg caatgagtgc tgcagccctt gttaaggcag caggtggtac tgcttatcag
     9661 gctagccaag cggtagcctt tgtaatcaaa aatctattgg gattggtttg tgatcctgtt
     9721 gctggattgg tcgaagttcc ctgtgttaag cgtaatgcat taggatcaag ctttgctctt
     9781 gttgctgctg atatggcatt ggctgatatt cagtcacaaa ttcctgtaga tgaggtcgtt
     9841 gatgccatgt atcaggttgg tgccgcaatg ccaacagcct ttaaggagac agctgaggga
     9901 ggattagcag caaccccaac aggtagacgg tatagtaaag aaattttcgg agactaatat
     9961 aatcacgtaa agatagactg aggagacagt atgaaagcaa tcctatttga cttagatggt
    10021 actttagtga attctagtat aggaatacta aacgcctttg aatacacctt tcaaaaaatg
    10081 aaaatccctt gtcctgatca tagcatatta tcatcttata tcggaccacc cttagaagta
    10141 accttttcag catttttcaa ggatcagcat gatgtcgagc ttgctatcac acactttaga
    10201 gatttttata aggaatcagg tatttaccaa gcaaggcttt atcctgaaat cacagagcta
    10261 ttagatactc tctcacaaaa aaaccttgac ctttatgtga caactagtaa atatgagcct
    10321 atggcaaggc aaatgcttca ggatttaaca attagccatt atttcaaggc tatcctaggc
    10381 tctattccta atcgttgcca caagttggat atcatcaagg catgcttaca agattttgcc
    10441 attaatcaaa aagaggctat aattgtcgga gataccaaat ttgatatgat tggtggcaaa
    10501 caagcaggca ttacaagact tggtgttact tggggatttg gctgtcaaga ggatttacaa
    10561 gcacatggcg cacaatacat tggacacaca ccccaagagg tgattgagat tatccagtca
    10621 ttgtaaaacg atactaaaaa cctatcatca cacaagatga taggttttta acgctgttat
    10681 ctgttcttag tagccccaag ctgataagcc ctgtgcacga taggcattta aggctgaatt
    10741 tacctgatcc tgaacggttg cagttgatcc ccagcctggc atggtttgga ataatcctga
    10801 agcacctgaa ggattagctg cgttagggtt tccatttgac tcacgagcga taatggcttc
    10861 ccaagtagct tgtggaacac cagtagctgc cgccatttga gctgctgctt cactaccgat
    10921 agcccctgcg gtattgccgt tagaaaggat tactccattg ctataagcca ctggtgtagc
    10981 tgcatactga gcttgaggag cagcctcttg cacagcagga ctagctacct cagaagctac
    11041 tgattcctga gctggtgctg catcagcaga ggaaggctct gcctgctcag ctggctgctc
    11101 cttggttgca gactttgcta ctgttgattt ttttgtttta tcttttttct taacaacctt
    11161 agagtcagag gacttagcat aagagtcagt gtttacattt tcacttgaaa aagcaaagac
    11221 tactgcaagt aaagcaatag cagctgctac aatgccaaaa ctaacataac gttgtttcaa
    11281 aatgtcttgt ttaaacatta aataaatacc tcacttttct ctgctatcca tattaactgt
    11341 taattattac ttgtctattt aagatatatt aaaaatatta cagcaatatt gatattccaa
    11401 gttttctagc ctgatatcag tgttttttga gcttaagaag ctcaaaataa aaacaatgcc
    11461 taagttcaga cctgtgtaac agatgattta agcattgtta ttattaacga atcctagtgc
    11521 tacagcctaa caaatagttt gctgtaatat agctaggtga gccctgaggg gctttttaag
    11581 tagaaaagga aaatccccaa aataactacc aaagcaatgg ctaggctgtc ttttaattgc
    11641 cagcttagca ggcggtattt tgttcgacta tcaccgcctt gatagcctct agcctccata
    11701 gcgatcgcta aagcgtcagc tcttttaaag cttgaagcaa aaagaggaat caaaataggg
    11761 ataatcgact ttaccttttg aataagattg ccttctccaa aatcaacacc tcgcgctttt
    11821 tgcgcattca taatacgagt tgtatcgtcc atcaaggttg gaacaaaccg taagctcaaa
    11881 gacaacatca aaccgatctc atgggcaggt accttaaacc taactaaagg cttcaacagc
    11941 gcttcaacag catcagataa gcttaatggg gtggtggtta gggttaacag cgtggaaaag
    12001 aaaataatca aaacaaatcg catgaaaatc aaaatggctt gacttaatcc caagcttgtt
    12061 atcttaatta ttccaagctg aaaaagaact gatcctccct gtgtaaaaaa aacttgaaaa
    12121 agcgttgtaa ataggataat accaatcata ggcttaacac cattgaaaaa gaaagaccat
    12181 tttatctgtg acaagaaaat cagcagcaag gtaaatgcta acagcaaaag attagttacc
    12241 acattattgg cccaaaaaat aatgataata tagataatca tagcaagcag cttgcttctt
    12301 ggatcaagcc gatgaataat tgaattccca ggaatatagc gaccaagaat gagtttatcc
    12361 atgctttaat acctctctta attcctccaa agtaatgggt aaatagggta aatcaaagcc
    12421 ttgcttagcc aggcattggg caaaggctgt caccttaggg acacctaatt gcttttcttt
    12481 tagcaaatca atgtgttgaa aaatagcctt tggctgacct gataagatga ttttaccagc
    12541 ctcaaggaca taaacaaaat cagcataatc agcaacatcg tccatcagat gtgttaccag
    12601 tacaatggtc atacctgatt gatggagcga tttaaaaaga ctcattaatt cctttcgccc
    12661 tttgggatca agcccagcag taggctcatc taacaccaaa atatccggct gcatcgcaag
    12721 aatacccgca atagcaaccc tgcgcatctg cccaccagaa agctcaaatg gatttttacc
    12781 aaatagatcc tctgaaatcc cgactagggt taatttttca cgcgctaagg cttccgcctc
    12841 tttctgagaa acaccaaaat tttgtggtcc aaaggccacg tccttcaaaa cagtttcctc
    12901 aaaaagctgg ctttcaggaa attgaaagac cagaccaacc tgcttacgaa taggcttaat
    12961 gtccttattt tttgactgat tagttatcgc cttgcctgct acggtaacct taccactagt
    13021 tggtagatgc aagccattta aaagctgcat aatcgttgac ttgcctgatc cagtgtgacc
    13081 aataaaagcc gtataagatc catctaaaat atcaagatta acgtcaaaaa gggcacgccc
    13141 ctcaaagggt gtccctgctt gatacgtgta gcttacatct tggaaatgaa ttgacatagc
    13201 tgctcctcta attccttttc tgtgagatag gctccctgta tagggaagcc atcttctttt
    13261 agcatattaa caacagaggt tgtaaaagga atatctaaac ctagattaat caactgattg
    13321 cccctggcaa atagctcctg tggagttgag acagactcaa cacgcccatt gttcatcacc
    13381 aaagctcgat cactaagagc cacctcatca agatcatgtg taatagatat aacagttaat
    13441 tgatattctt gtctaataga ttgaattgtc cgaatcaact ctagacgccc ctttggatcc
    13501 agcatactgg ttgcttcatc taaaataatg atcattggcc gcatggcaac agcacctgca
    13561 atagcaaccc gctgcttttg accacctgat aatctggaag gctccttatc cttaaaagcc
    13621 tccataccga ccagctgcaa cgcctgataa acgcgatcta tcatctcctg atgggaaaca
    13681 cctttgtttt caagaccaaa agcaacatca tcttcgacag ttgcaccaac aaattggtta
    13741 tcaggatttt gaaacaccat gccaatttta tgacgaatgt cccagacatt ttcctctgta
    13801 agaagatcac cgtcaacaaa aatctggccg gcttctgctt tcaatagccc atcaattaac
    13861 ctaacaacgg ttgacttgcc tgaaccatta tgcccaatga tagacaacca ctcgccttgt
    13921 ttcacatgaa acgtcacatc atctagggta tatcgctcct gatcctgctt atacctaaat
    13981 gtaagattct taacttcaat aatatttgac attgttattt aaaggtatcc ttaaaaagaa
    14041 agcttgctcc tttgaaataa tcgtaacctg aataaatcgt aaacaataga gcaatataca
    14101 gcaaaacagt gcctaaaaca gtccaatgac acagtaaaaa aatgatggaa agcatctgtg
    14161 ctactgtttt gatcttacca ggcatagcag ccgctaggac ctcacctcca gtctcaacca
    14221 gtagcaaacg aagtcctgta acagctagct cacgacagat aataaccgct gacacccaag
    14281 ccggtaccag ctctaagccc actaacataa taaaagcact catgacaagc atcttgtctg
    14341 ccaacggatc agcaaattta ccaaaattag taacaacctg ccactgacgt gcaaggtaac
    14401 catctaaata atcggtcagg cttgccactg caaaaataat cgctgcaaaa gtatgccaac
    14461 cgactgtctt tgaaaaagag gtgatcaaca aaaacaatgg aatcatgacg atacgggcga
    14521 gagttaacaa gttgggaata ttttcttttt tgatcatgct tataccttat tattgtatct
    14581 tcagtgtgat atagctgata tcagtgcttg tcattgctga taaatctagg ggctgaccat
    14641 caattgctac tgaaacaccc tttgttacgc ctagtgtcaa caaggattct gttgtctcag
    14701 caggcaaggt agtagaataa gtcggattgt cctttgttag ggtcatacca gcctcaccaa
    14761 tttccgaatt agtgagggaa atccaactgc tctcagcatc agtcagtgac actgtaacat
    14821 caacagcttc ttttgattta gtaatattag caatcaagta attctctgcg ccctctgttg
    14881 tgatcaccgt cttaggctca gatgagctgg acgctgttga gtgactgctt tgtgatgact
    14941 taagaaaaga catctcagcc tcttttgctt tttgaccttt atcaaattgt ttccaaacag
    15001 caaaaccaat gacaccaaca atagccacag caataagacc tagtaaggct gatggaaagg
    15061 ctgatttttt cgttttagca ctatttccat aacgacttag tcttgaagca ctggtctctc
    15121 tagtccgtct atggtcagta gctttaaagt gactagctgt aggagctgat ttgcttgagg
    15181 atagtgatgt cttgacagga atcactaggg tttctggttg agtccttgaa ggctctggtt
    15241 gagctatttt ttcagaatag ctattctctt gtagcctttt tttgctgagc ttttcttcaa
    15301 cgatttgtgt gactgatggt gtacctgttt cctttttaaa gctcacctgc agctgataca
    15361 agcgttttaa gctatcaaag tctaagccaa caatatcagc atattgcttt agaaaatgac
    15421 caaacttttc ttctggaatg attttgaact ggtcaagctc cattgccaat agataatgcg
    15481 aggaaatgcc agttttagct tcaatttcgt ctaatgttat gttttttccg acacgtgttt
    15541 ctcttaataa ttcaccgaga cttgtttctc tcatacgagt acctcaaaaa tattgtaata
    15601 agaccattat aacagatttt aagctatttg ggaaagactg taaaatctga agtagctgca
    15661 tgctcaaaaa acaagcttcc tatttcgata atatccttta aagctagggt ctcaataatc
    15721 ctaggaatat caaaataggt ctcttgctct gataaatgaa ggctaaattg gcttgccagc
    15781 tgatcaatag cgtctaagct ttgcataaaa tccccatata tttccttttt cactagctct
    15841 aagtgctcct cattaatgtc tcttgagcat ctaaaatcgg aaatcttttt tctaatgctg
    15901 ttagacattg caataggctg actagtatct gaagaaatca atacaaattg gaaatccctt
    15961 tgaatgtcaa cctctatatc aaaggagtcg tctatcttgc ccttttcata ccaatcctga
    16021 taggcttttg acgtccagcc aaggagcatc gctaggagca gtctaagagc tacctgatag
    16081 gtgagtagag aatactcgct tgacattagc tgaccgcgaa agccgactgc taatttggca
    16141 ctcgcaacgt ccatatcaat agatctagac ttgatcacag ggtggtaggt caatggagct
    16201 atctgtacat catactgcgt ctgacttggt tgactatctt gaaaggcttc aatagctgta
    16261 aaggcttctt caatatcaat atcgccaata atcgttaaga ccatgttaga agggtggtaa
    16321 aaataagcat ggctgtcagc caataaagag cctgtaatgt ccctgataga ctccttggtc
    16381 ccagcaatgt caacagctaa gctggtattg ggaaagaggt tctgtaagat accactgtaa
    16441 gcctgataat caggatcgtc ctgatacatc tcaatttctt gagtgataat atgtttttca
    16501 cgattaaccg actcctctgt aaagctagga gctgctacaa attcctgcaa aagtctcaga
    16561 ctttcttgcc attcattgac agttgaaaag aaatagctcg ttttatcaaa ggttgtaaag
    16621 gcatttgttt ctgatcctaa ctgtgtaaat gtaagagcaa tatcattacc atctttatcc
    16681 tcaaatagct tatgctctaa gaaatgagca acacctggcg gtaagttaac cctttgacaa
    16741 ccaactgtaa agcttgtgtc aagagaacca aaatgagcag tcagcatggc tgttttctca
    16801 gaatagccct ccttttttat caaataaacc cttaaaccat ttgccagttg accgtagtgt
    16861 aaggtctctt taatgctggg atagtctttt ttcagtagtg gtgtcatctt attttccctc
    16921 taaaaaatat acagcttgca gcttgagcag gttagctgtc ctgacaatat ctagcttgct
    16981 aaccttgtca atctcgtcaa tccagcttga caaagtatag gaaggatcta tataagttct
    17041 catatattcc agctcaatca aggctttact attatcctca gatagcaagg cgttattttt
    17101 tagcattagc tttgttttct tgacaaggct gcttgaaaag cgccccatct tgatgtcatt
    17161 gagctcttta accattagct gcagggctct tgtccggtgc tgtctatcta tgccagcata
    17221 agcctcaaat aagcctgtgt aaacatcaaa tcgactacca atactatagg ccagcccctc
    17281 cttctcacga atttgggtaa agaagcgaga gtgtgtaaag gctcctaata gaccatttaa
    17341 cacaactaag gcataatact ctgcttgccc ataaaccagc ggaaaatggt aggctagctc
    17401 taaaacagac tgattaagct gcttttgctc gaccaattcg ttgacaacat tgacaggctg
    17461 ctgtaaataa aagaaatcta gctttttcct gcgtccctca aagggaaatt ggtgtaacaa
    17521 ttgtaccata cgataatcat caaaatcacc aaggataaaa atatcaatct gatcctcatt
    17581 caacatttta tgaaattctt gatagcttgt gtaggctgtt tccttagcaa ttaactcagt
    17641 attaccatat tttgacagct tcaggctatc attagcataa aataattgct tggtttttag
    17701 ggtactataa taaaaggaat cctccttgtc tgcctcgaca taagtcatca aatgtctttt
    17761 ttcaatgtca aatagtttgg gctggtactg agccactgat aacaaaggag aaaaaaggat
    17821 atcctttaga aattgaatca tttcatctag aagcttctct ccataaaaag catactgatc
    17881 ctgaataaag gtaatgtcaa tatccacaat atgaaccaaa cccttggttg acacatgagt
    17941 tgacaggctt gctccataca tttgtgctaa tttttctcta aattgcttgg cagtaggata
    18001 ggtatcgtta gccgttgcta acatttgagc tactaagact cgctttgcta ccgttttttg
    18061 attcaaatca cctgaaaagc gaaacgttat ctgattcgtt ttaaatgttt tgttttttat
    18121 cagatgaagc tgaactccct gaataagttt cataatattt ccttattaat aaatgtgtga
    18181 tctctagaat tataccattt ttatcgctat tcgttgagtg ttaacatcag tctggtagcc
    18241 tattttgact ctttatcaaa atgctatcct gtggctatag tctagacttt agaaggtcag
    18301 catttcagca ttattattta gtggcttttt atgctataat gacttgaatg acaaattgga
    18361 gatgactatg acatacacac tatttactga ctttattacc ctacaagctt tattaaagga
    18421 gcaaggtatt atccaaagtg gtggtgccat taaaggtttt ttagctcaaa cagaggtttt
    18481 tttaaatggt caagaggaac aacgacgtgg caagaagcta agagtcggtg acgtcatcac
    18541 cattccatca cagcacatca agattgagct tgtagcgcct agtcaggccg aaaaaacagc
    18601 ctatgaagct gaaaaggcag aaaaagagcg agttgctaag atggttaaac aaatgaatca
    18661 acaggctaaa aaagcacaga ccaagcaagc agctactacc aaaagcaagc gtggtcaagc
    18721 tacctcagct gtaaaagcta agtctaatca ccaaaagcct attcgcttcc caggattgta
    18781 gcatgtggat caaagaacta aacctcaccc attaccgtaa ttatcaacaa gcctcagcag
    18841 ccttttcacc aggcttgaat gttttcattg gtgacaatgc gcaaggaaaa acaaactttc
    18901 ttgaagctat ttattttttg tcagtaacaa gaagtcatcg caccaaatct gataaggact
    18961 taatctactt tgacgaaagg gattgctcta tatctggaac tcttgagcgc cttagtggtc
    19021 gtgttcagct agaaatacta ctgtctgata aagggcggat caccaagatt aacaccctaa
    19081 agcaggcaaa gctttctgat tatatcggag caatgatggt ggtcctcttt gctcctgagg
    19141 acctacagct ggtcaaaggc tctcctagtc ttagacgaaa atttatggat attgacttag
    19201 gtcagataaa gcctgtttac ttatcagatt tatcacatta caatcatgtc ctaaagcagc
    19261 gaaatgccta tctcaaaagt gttcatcagc tggatagtga ctttttgtct gtgttagatg
    19321 agcagttggt tacctatggg agtcgtgtaa tggcgcatcg gttggcgttt gttcaatcac
    19381 tagcaaaaga ggcaagcaag catcatcaag ctatctctaa tggcctagag aagctttcaa
    19441 tctcctatca agcctctgta agctttgagc accagcaaga gatttatcag caattcatgg
    19501 accagcttaa agcaactcat caaagagatt tcttaagaaa aaatactggt gttggtcccc
    19561 accgcgatga tttggttttt tatattaatg acatgaacgc taattttgct agtcaaggcc
    19621 agcatcgtag cctgatttta tcactgaaaa tggcagaggt tagtctgatg aagcaattaa
    19681 caggcgacaa tcctatcctt ctacttgacg atgttatgag tgagttagac aatatcaggc
    19741 aaacaaagct tctggaggct gtcaaaaaag aaaatgttca aacctttatc acaacaacta
    19801 gtttagagca tttgtctcag ctacccaagg acattagtct ctttaaggtt aataaaggga
    19861 cgattgcact agattctgtc atgattgatt aactgagtaa accaaaaaag ggcaccttaa
    19921 cagtggccct ttttatggtt aaatcagttg atactctatg acttgacgat acctaagagg
    19981 atagcgccaa caataaagca aaggatacct gtaataaccc agcgcatctc tttttttgtt
    20041 tttgtctcgc ctaagaataa aatacctccg acaatagaga taatagcgcc caattgtgaa
    20101 aagctaaaag caattgccag accagccttt gaggctgcta gcagcatgaa gatatttcca
    20161 actccccaaa gcaagccaac aacactgttt ttgataacat actggtcaaa cgatacctta
    20221 aacgacataa acatggctgc accaagcacc atgcccactg ccatcggtaa aataaccgac
    20281 aacacatcaa atttcataat gttattgaac aacacagcat acatcacata gccggttgtt
    20341 gagtaggtta aggctctaaa gccctttgaa aaatcatgca attgattact tgctgcattc
    20401 gtctcgtcct gcttgcttga aaaataaaaa ccaacaatca aaagaagtaa ggcaatcgta
    20461 ccaacgacaa attgaatagg cttggtccac tcatgaaaga ccagcacacc aatcagacta
    20521 cctaaaacta gctgagaacc actagacaag ggatttgcta ctgaaacacc catatactgc
    20581 atggcatgaa attgcccagt ctgaccaaca gaccagataa caccacctaa aatcccaaaa
    20641 atccagagct tcatagacat ctcaggtctg accactagcc aaacaactag agcaaatagc
    20701 aaagctccta gggtcatccc aaaggtctgc tgtgagggtt taccgccaat tttattacta
    20761 acaaaaccaa tacttcccca tgcaaacatt gggacaagtg caaataaaat accttccaaa
    20821 tttacatctc ctttacaata agttgacaca tgatgttaac gataaaagtg ctttcatacg
    20881 gagaactatt atagcctatt tccttagaaa atacaataac atcatgtcaa aaatcagctg
    20941 tttaccctaa tttccctaaa aaggtgtcaa agcagcagat agagcttatt tactgcaatg
    21001 ctagaggatt attcaatgaa aaccgtttgg cctgatggct ggctctaact ggagctttgt
    21061 tagggacttt tgtgacatga gttccaaagc aatcagcgac tagctgactg aaatagccta
    21121 agcgtttgag aagtagggca agatgactaa ccatagcact agctgccttg ccggacatgc
    21181 ttacttctat ggtagctttg acaaaggata gctcaacgat gattttatcc agtagcctgc
    21241 caaccatctt ttgactagtg atgataccat ctaaatcaag agcgctgtaa actccctttt
    21301 cgatcaagcg actgagatct cgatgcaggt tttgaagccg atgccttgcg gtattgactc
    21361 gctgtatcgt atcggtcaat gctggtacta gaggacatac ctcaactctg gcagaagcaa
    21421 taccggatct tatgcgataa ggatataagg tacccagatt tccccaatag tcccttgtcg
    21481 ttatggaggt ttcatctttg atttctgttc gttcaacata aaccctatct gaaaaacgtc
    21541 tgtctaacac tgttacaata tccttaaagg tattcacctc agtagtccaa taatcaagtg
    21601 tatcaaatag ccttgaaaag gttgacgcat aaacagaggc aacctttctg gaatagtccc
    21661 gactcttttg ttccatctgc tcatcaaagg cttggagaat atctctgaca tcatctaaaa
    21721 gacctgttct ttctaagtaa gcatcatagc tgcttgggac acagacgaca tcagcacttc
    21781 cttgaaattg accatttttt aggctgttgc ctagccagtt atctgtagct gtgacatttt
    21841 gtgatacccc taggatcagc tcactggtat tgattatcat tttttccagc tctatgatat
    21901 cctgtaattc cacgcgaaat acctctttta aggaatcgct aataccgtca gctttacttt
    21961 cacgtaaacc agttccttca aaggtcttat cactctcctt caatagctga cgactggcct
    22021 catcaataat ctgccaagat ttcaaaagtg tcgagcgacc gataatacta tcaatccagc
    22081 ctgatttttc atgctgagca gatgaggcaa gctgaagcga ctttgtgttt aagctcgcta
    22141 attctgaatc atacatggcc agattgaggc gattattatt cacatatggg atctcatcat
    22201 aggaaaaggg atagtctagg ctagccgaat gagacagcat atcaaacaag tcctgctgac
    22261 caactaatct ctccaaagag ctttgcagac tattgaaggt atcggttagg ccatttgtag
    22321 caagcagggc tttgatgttt tctgaaactc gctttttcct ctcttcaaag gagtctttta
    22381 tgacatcatt ttttgcctga catttttcag taatgtagcg aatcgtttgc aagtctccta
    22441 atatagagga ttgaaggttt tgtgcaaggt tagtcaggac accagcattg atgacaatcg
    22501 tttgcttatc agaaagcaca ccgtatcgag ccgatgttga cgcatcaaag taatttctaa
    22561 agcctaggta cagctcctct accttagtgt ctaatcggtt atcgctgtca atatcaacag
    22621 gcaacaggac attagcatga acaaaccggc catttacgtc tgtcatgttg ccatattgat
    22681 catactgata gccatgccac atatgctgta agactatatc attgaccttt tttgtattga
    22741 caacaaagac ctgaccgact gctccctcct tttggtcaaa gcccatacca ataatgtcat
    22801 gcggatccac atagttgtaa atgcggtcat gcaagtgctt tgcacgtttt ctttgatact
    22861 cattaagcac acgataggtg ttggggccat tgtagatata gactccagag atacgagata
    22921 agtttttatc actaacagag gtaacgccgt actgaactgt catggagcct agcgaatgac
    22981 cataaaactc aaatgttgcg ttagggtatt gctttaatgt cttattggta aaggttgctg
    23041 cctttcggag ctgagctgtc cctttagttg gtgtctggtc cggtaaaaga atgcgcatag
    23101 ccataggcaa atcattgcct acccaatctg caaccacatc tactgggtgt ttctgccact
    23161 ggtctgggcc agtagagccc cggtacagca ttgtgacatg cttgacctga gcatagtctg
    23221 ccttggtagg atgaggggga agcttgacat ctgtcacgac ataggcttga aaacctgata
    23281 tcgaatcctc tatctgagac acataaccga tgaagaattt agagttacta tctttaacaa
    23341 taaccggtga acctactgta tgttcttcat atccctctgc tgcaatttct tttctttgtt
    23401 catctgtaaa aatcatcaat caatccctct ttttctaata acttttctag tttttcggaa
    23461 tagtatatgc tagcaatctc caaatctctt tcccaattac gccgatcaag acgaaccctt
    23521 aagtaagtat caggatcatt attaataatc aggtgaatgg aaaagcctcc cattggatta
    23581 ataaagagcg agtctgagtc gatagtgtag gacttaataa gcccttcaat tgtcaaggct
    23641 tgtggatcta ttgatgttaa ctccttttca taaatatcta tcgcttcttt actatgcgcg
    23701 tttttgagct ctacctgttt gatttgatta tagatatcca ttctatgttt tacctccatg
    23761 ccaagaataa gtacaagagc accaacaata aatacaatga gttttaacaa tgttttcatt
    23821 tctccactcc ttttagtagt ttttctaact tttctgagcg atagatacca tcaatctcca
    23881 aatttctttc ccaatcatat ctgccaaaac taacccttaa gtaagtatca ggatcatcat
    23941 tgataatcag gtgaatggaa aagcctccca ttggattaag agttattgag tctaaatcaa
    24001 tagaatagga tttaatagtc ccttcatttg tcaatgcatt tgggtccaac cattttaact
    24061 cctgttcata aatcacaatt gcttctttac tttgggcaat ttttatctcc tcctgcttga
    24121 tttgatcgta tatatccatt ctatgcttta cttccatgcc aagcataatg acaataacac
    24181 caacaataag cagactgatc tttaaaaacc tattcatgtc tat
//
LOCUS       DARYSY010000032        23756 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYSY010000032 DARYSY010000000
VERSION     DARYSY010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23756
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(8..646)
                     /locus_tag="TVR04_001189"
     CDS             complement(8..646)
                     /locus_tag="TVR04_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1269886.1"
                     /translation="MKYGYIRVSTKEQNIDRQLSAILKEVGDMKQIYIDKASGRDFER
                     KKYKRLIRTLKEGDELYIKSIDRLGRSYDDIIKQWHLITKVKNVDIIVLDFPLLNTKH
                     QINNLTGKFLSDIVLQILSYVAQIERENTHQRQMEGIKEARKRGVKFGRSKKEVPKQF
                     DDVVTMWVDKKISLREGAKLLDVSHTTFSKWIQEKGYMREKKKNLDKIKAHK"
     gene            complement(813..1052)
                     /locus_tag="TVR04_001190"
     CDS             complement(813..1052)
                     /locus_tag="TVR04_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1269887.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(1062..1334)
                     /gene="rpsP"
                     /locus_tag="TVR04_001191"
     CDS             complement(1062..1334)
                     /gene="rpsP"
                     /locus_tag="TVR04_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1269888.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(1571..1717)
                     /locus_tag="TVR04_001192"
     CDS             complement(1571..1717)
                     /locus_tag="TVR04_001192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269889.1"
                     /translation="MVKKGRVPACAGTVLFDMIISLSYLFDVKQTAPLTSGYACLIKL
                     LMIK"
     gene            complement(1769..2386)
                     /locus_tag="TVR04_001193"
     CDS             complement(1769..2386)
                     /locus_tag="TVR04_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1269890.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILLSVMLVVYLVRQLDIINNPK
                     ALAHLIKDHLLIGAICFFVLQIVQVVVPIIPGGVTTVVGFLAFGPILGFVLNVFGICI
                     GSFILFKLVRTYGKPFILLFLSKEQLHFYEEKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(2379..3602)
                     /locus_tag="TVR04_001194"
     CDS             complement(2379..3602)
                     /locus_tag="TVR04_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1269891.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(3614..4324)
                     /locus_tag="TVR04_001195"
     CDS             complement(3614..4324)
                     /locus_tag="TVR04_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1269892.1"
                     /translation="MPDEKKELIQLKNIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(4324..5586)
                     /locus_tag="TVR04_001196"
     CDS             complement(4324..5586)
                     /locus_tag="TVR04_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1269893.1"
                     /translation="MSKRGKMKLSTKTKGIIAGAVALTVVVIGGVLWKQQQNTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSATGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(5842..9018)
                     /gene="carB"
                     /locus_tag="TVR04_001197"
     CDS             complement(5842..9018)
                     /gene="carB"
                     /locus_tag="TVR04_001197"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1269894.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNLAMEL
                     SKAGILQELGVELLGTPLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEGAISFAN
                     AIGYPVIVRPAFTLGGTGGGICTNEEALRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFEQGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQELVKKPVDIDLLTEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDRAEDRKLFEKALKELGIPQP
                     PGQTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENEDDLLSYMKTAIKASSEH
                     PVLIDSYIVGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILDQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHTPEYGTIVFTIADDHKPEALALARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGGNAHDIPALLRKGQIQAIINTVGAKRVADQDGQVIRSSAIEQ
                     GVPLFTALDTAAAMLRVLESRTFSIEAI"
     gene            complement(9436..10527)
                     /gene="carA"
                     /locus_tag="TVR04_001198"
     CDS             complement(9436..10527)
                     /gene="carA"
                     /locus_tag="TVR04_001198"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1269895.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGIQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(10550..11485)
                     /locus_tag="TVR04_001199"
     CDS             complement(10550..11485)
                     /locus_tag="TVR04_001199"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1269896.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGKYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRQLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(11543..12802)
                     /locus_tag="TVR04_001200"
     CDS             complement(11543..12802)
                     /locus_tag="TVR04_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1269897.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYVFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(12818..13339)
                     /gene="pyrR"
                     /locus_tag="TVR04_001201"
     CDS             complement(12818..13339)
                     /gene="pyrR"
                     /locus_tag="TVR04_001201"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1269898.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPE"
     gene            13701..14315
                     /locus_tag="TVR04_001202"
     CDS             13701..14315
                     /locus_tag="TVR04_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1269899.1"
                     /translation="MNDITRKINHKQLIQVTTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFIFPGFPDDFLCM
                     VAGLSSMSVKKFISIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(14395..15285)
                     /locus_tag="TVR04_001203"
     CDS             complement(14395..15285)
                     /locus_tag="TVR04_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1269900.1"
                     /translation="MEIKMTESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGSPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHVKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSDKDRKKQTVTAKGKEALTRFKVLERFGRYSLV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGNGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(15275..15733)
                     /locus_tag="TVR04_001204"
     CDS             complement(15275..15733)
                     /locus_tag="TVR04_001204"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1269901.1"
                     /translation="MKRISFVIAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITILVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRMRLSYVVDMIHLDVINFAIFNVADSYLTVGVLLLVICLWKEEDYGN"
     gene            complement(15983..16891)
                     /locus_tag="TVR04_001205"
     CDS             complement(15983..16891)
                     /locus_tag="TVR04_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1269902.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTTGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSVASQHYDFL
                     PALITSFAQKHDGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKSHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKRK"
     gene            complement(17286..17579)
                     /gene="rpmA"
                     /locus_tag="TVR04_001206"
     CDS             complement(17286..17579)
                     /gene="rpmA"
                     /locus_tag="TVR04_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1269903.1"
                     /translation="MVKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(17601..17933)
                     /locus_tag="TVR04_001207"
     CDS             complement(17601..17933)
                     /locus_tag="TVR04_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1269904.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSIEQMTGLEPALEIVDDGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHSSE
                     YVQKPVMN"
     gene            complement(17946..18260)
                     /gene="rplU"
                     /locus_tag="TVR04_001208"
     CDS             complement(17946..18260)
                     /gene="rplU"
                     /locus_tag="TVR04_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1269905.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(18294..18368)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(18490..19683)
                     /locus_tag="TVR04_001209"
     CDS             complement(18490..19683)
                     /locus_tag="TVR04_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1269906.1"
                     /translation="MLKDFQYKKTMLSVLTLIVAALAFALAFDLLGMPKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEDRI
                     QKDLIRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            19947..20564
                     /locus_tag="TVR04_001210"
     CDS             19947..20564
                     /locus_tag="TVR04_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1269907.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELIAIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLALSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(20859..22088)
                     /locus_tag="TVR04_001211"
     CDS             complement(20859..22088)
                     /locus_tag="TVR04_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1269908.1"
                     /translation="MRVLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTRRKTRNLIIIGFIQSLLFTIVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFSQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEVGVSLMKQFRVMYTS
                     MTETFKKTDHVSFVKLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSIVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLAQTQGIAFLLVGASNAMQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALTLSTSSTRG"
     gene            complement(22160..22345)
                     /locus_tag="TVR04_001212"
     CDS             complement(22160..22345)
                     /locus_tag="TVR04_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269909.1"
                     /translation="MRKPRITKKCIYKEDSRERSSSFEKSFEAYVEKKVKTIIEHPEK
                     YPFIQLVHGEAYGSDKL"
     gene            complement(22664..23531)
                     /locus_tag="TVR04_001213"
                     /pseudo
     CDS             complement(22664..23531)
                     /locus_tag="TVR04_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         7091 a         5412 c         4200 g         7053 t
ORIGIN      
        1 ttttttatca cttatgagcc tttattttat caaggttctt tttcttttct ctcatatatc
       61 ccttttcttg aatccatttg gaaaatgtcg tatggctgac atcaagaagc tttgctcctt
      121 cccttagact gattttttta tcgacccaca tcgtgacgac atcatcaaac tgtttaggca
      181 cttctttttt gcttcgtcca aatttaaccc ctcttttcct tgcttctttg atgccttcca
      241 tttgcctttg atgagtgttt tctctttcga tctgagccac ataagacagg atttgtaaca
      301 cgatgtccga tagaaatttc cccgtcaaat tattgatttg atgtttggta ttcagtaagg
      361 gaaaatctaa aacgatgatg tcaacgtttt tcactttagt gatgagatgc cattgtttga
      421 tgatgtcatc atagcttcta cccagtctgt cgatggattt tatatagagc tcatcaccct
      481 cctttagtgt tctgatcagt cttttgtatt tcttgcgctc aaagtccctt ccgctagcct
      541 tatcaatgta gatttgtttc atgtcaccga cttcttttaa aatagcactt agctgtctat
      601 ctatgttttg ttctttcgtt gatacgcgta tatacccata tttcatcttt taacctcctg
      661 attgatctat tgttacacat aagatgttat acagatacct ctgtcagata gagttcttgc
      721 ttttgtgtct tgacctgacg attcaagata caaaaaaagc ctgctagaca gaactagcaa
      781 ggctttaaga ttagtcttgt tcaaaataga acttattttt catcaatgac taatcgaacc
      841 ttttttccta aagttggcac cgaatagaca atcgatctta tcgctgtgat ggtacgacct
      901 ttctttccga taacacgacc gatgtcttga gcatccaagt caagatggta ctctaaaaaa
      961 tccggagtat cttcaatttt aatagtaagc ttatctggtt gtgaaatcaa gggcttcaca
     1021 atagcgataa tgagattttc aatggtatcc ataggctttt attacttaga aaacttttga
     1081 tcgtggaatt tagccataac cccagcttta gacagaaggc tacgaactgt atcagaaggt
     1141 tgtgcacctt ttcctagcca atcaagaaca cgatcttctt taagagttac ttgattttca
     1201 gctacaagtg ggttgtaagt tccaactgtt tcgatgaaac gaccatcacg tggtgcacgt
     1261 gaatctgcaa cgttaatacg gtagaaaggt tttttcttag aacccatacg agttaaacgg
     1321 atttttactg ccattttaat atgtctcttt tctttaaatg ataatagtca agaaatgtag
     1381 tcttgctcat ttcttaccta accagtatac tttacttttg attttgtgtc aagttttttt
     1441 cttgacactt ttttatgatc ataatactac tcaacatctt caatcagcta agctgcttag
     1501 atgacatcaa acagcaggca gctgctttta tgaaagcata cagctccaag ctagcctact
     1561 ctagtgaccc ttacttaatc atcaataatt tgatcaggca agcataacca ctcgtcaaag
     1621 gagcggtttg tttcacatca aaaaggtaag acagactgat aatcatatca aaaaggactg
     1681 tccctgcaca tgcaggcact cgtccttttt ttaccaatat gacttagcca ccttgctttt
     1741 aaggctgagg tattggctaa gcgttacact aataatgcat caggatatgc ttgaggaact
     1801 ccccaccata aatccaaaaa taactgaagg tcaaaattga aatgggccta caaattagga
     1861 taatcagtaa aaagcgcttg taggtcatct gactcaatcc agtgatcatg atgagagcat
     1921 cagcaggagc tagaggagaa atcatattga gaataaagaa acgctcaaat aatttcgttg
     1981 atagcttctc ttcataaaag tgtagctgct ccttacttaa aaacagtaag ataaaaggct
     2041 ttccgtatgt cctcaccagc ttaaacaaaa taaaggatcc aatgcagata ccaaacacat
     2101 ttaaaacaaa gcctaatata ggaccaaagg ccaaaaaccc aacaactgtg gtcacaccac
     2161 caggaatgat aggaacaacc acctgcacaa tttgcaggac aaaaaagcaa attgctccga
     2221 taaggagatg atccttgatt aaatgagcta aggcctttgg attgttaatg atatctagtt
     2281 gcctaacaag gtaaacaaca agcatgaccg ataacagaat tgataagcca ccaagaatct
     2341 taaacagctt ctttaacaac gaatgtgaaa caccaaagct actcatagcg caaagcctct
     2401 atcggatcaa gcttgcttgc tttgtttgct ggcagcaatc caaaaataat accaattgat
     2461 gccgaaaaga taatagctac agccgcaaca tctaaggaaa cagctgctcc ctttaattgc
     2521 atcgcatttc ctagcacacc tacacacatc tgtgctagca gcagccctaa aagaccacca
     2581 attaacgtca acaccactga ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct
     2641 cccaaggctt ttcgcaagcc aatttcacga gtacgctctg ttacagatac caacatgatg
     2701 ttcataacac caataccacc cacaagaagg gaaattcctg caatggaccc aacaactgtg
     2761 gtcatgatac taaattgtgc gttaatgtca ttaataattt ggctattgtc aggaacagca
     2821 tactcgccct ccttaacatg agacagtgtc gtcaacatag cagctgcctg atttcctaat
     2881 tcaaggcttc gcttaacgtc gccaatataa agatagacag agccaatttc cttgacatga
     2941 aattctgagg ccacctgagt attggccata atggctcctc cagaaatccc accagcaaac
     3001 gaaacaacct cctgatcagt cttgtaaaca cctactacaa ggtaatcctt gctatctaga
     3061 ctaaccacct tatttagagc ttgttcataa ttgcctttgc caaataattc gtcagccaag
     3121 acagtatcta ataggataat gcgagaaaaa tttttataat ccttgctatt tagcgtccta
     3181 cctgcaacaa tatcatattt tttgacttta aaataatcct gactaacccc agtgatggcc
     3241 acattgtcca tcttcttttt ctcaaaagaa atggtagagg ttgaattatt ggtatagtaa
     3301 taagaatcta ccccatcaat tgctttgaca atctgctcta gccattcagg cttgacctct
     3361 tgctcatttt catgcgctgc aaaggccgcg taagggttgt cctcatctcc ttttgccttg
     3421 aaataaagct gaacctcttt ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg
     3481 gcagcaccaa gccccatgat aatcacaaca gcagctacac cgataataat tcccagcatg
     3541 gtaagaatcg aacgcagctt gtgcccccag attgaactaa gagcaaattt ccaattttcc
     3601 atcacttttc ctcctagtca atcctgacac tttctgttgt atcagctgtg atttcaccat
     3661 cacgaataac aatttttcga gtggcaaagt ccgcaatctc cggctcatga gtaaccataa
     3721 taatggtttt accctcctta ttcagctccg tcaaaagcct cataatctgc tcaccagtct
     3781 ttgtatctaa ggcaccagtc ggctcatcag ctaagataat agacgggtta ttaaccaagg
     3841 ctcttgcaat ggcgaccctt tgcttttgac cacctgataa ctctgatggc aaatgcttca
     3901 ttcgcatacc aagctcaacc ttttccaaaa attgcttagc caattcacga cgctttgata
     3961 ctccaactcc agcataaatc aagggaagct caacattttg cagggcattt agctttgcta
     4021 gtaaaaagaa ctgctgaaag acaaagccaa tctcttcgtt tctcacctga gcaagctttc
     4081 gatcatttag gatctcaacc tgtgtgccat tgagacgata atcacctgag gttggtctat
     4141 ctaataagcc gatgatattc atcagggttg atttccctga gccagaaggc cccataatag
     4201 cgacaaattc accttcatat acagtcaaat ccacgccttt taggacctgt agctcctgat
     4261 caccattttg atagctttta acaatgtttt ttaattgtat taattctttt ttctcatctg
     4321 gcactactta atcacctcgg attctttact gcttttttta gaatcttttg atgcctttgt
     4381 gtctgcggaa ataacgtctt ctagcttttc accctctttg atgttcttat cagggttagc
     4441 aatgacaata tctcccacct ttagacctgc acttacttct tgtctttcag catcagcatt
     4501 gcctagggtt acttcaacct ttttagcctt tgcagttgag tcatcataga cccagacaaa
     4561 atgcttcttg cctttgttaa cgatagcagt aactggtact aaggcatgct ttgcttcgtt
     4621 gataacctca acagacaccg taaaaccttg ctttagctga ttaagtggac tggtgatatc
     4681 aattttatag tcataggttg caccagttga gcttgatgag cctgagcccc ctgtagctga
     4741 acctcctgca ttggcatcag ttgggtagtt tgacacataa gaaatctttc cggtccactc
     4801 ttgatcagca tagacctttg atttaatctt tacagcttgt ccgaccttaa tattggccaa
     4861 atcatactct gtcagggttc ctttgacctg tagcttacct tctgttgcaa catgaaccaa
     4921 ggtttggcta ttttttgaag acgggtcaat atcattatta acctctacaa ctgttcctga
     4981 cacaccactg acaactactg tttcatttaa ggcctgctgt gctttattga cctctgcttg
     5041 agcatcagca taggaatcat ttaaatcctg caattgctga gcatagctag cattttgctg
     5101 ggctgagggc tgaatagttg tagtggtttc ttgtcctgtc tcctcgtcct tgcttgtctc
     5161 agtggttgca gctggaacac catacgtttt taaatgatta atctgacgac cgattttatt
     5221 gagattgcga acagcggtgt cataagctgc ctgtggtaca gtggtgttgt attgtactag
     5281 ctgctgtccc tgtgtaacct gatctcctac cttaaccgta acggtagcgt ctgaaccttt
     5341 gctagcatca aaataaacgt attcttctga aagagcttta acagtaccag agagtaaggt
     5401 tgaagaggct attgtccctt ctgttacatt taccgcagaa taaggcaact tgatattttg
     5461 gtcagagatg gtattttgct gttgcttcca taatactcca ccgataacga ccacagttag
     5521 tgcaactgca cctgcgataa tgcctttggt tttcgttgat aacttcatct ttcctctttt
     5581 agacatttct gtcctcccct tttgtactat ttttgtaaga caagtatatg atgtttttaa
     5641 aaacttgtca agaatttctt ggataagctt aataaaacag cctcttcatc atgtagatga
     5701 caactctatt ataatggttt ttcaagctgt actagcttac acttttgtaa tattaaaaag
     5761 agaacaagcc tagttttcga aatctcagaa aactagactt gttcgtttgt ttagactttt
     5821 ctctcagtct cttcatcagg tttaaatagc ttctatgcta aaggtacggc tttcaagaac
     5881 cctaagcatt gctgctgctg tatctaacgc ggtaaataga ggaactccct gttcgattgc
     5941 tgagcttctg atcacttgcc cgtcctgatc agccacccgc tttgctccta cagtattaat
     6001 aatagcttga atctgtcctt ttctaagtaa ggctgggata tcatgagcat tgccaccgat
     6061 ctttccgact aactgtgagt ctagcccttg gtcagcaaag aaagcagctg tgccttcggt
     6121 tgccatgatc tggtagccaa tagcactaaa gcgtctagct aaggcaagag cctccggctt
     6181 atggtcatca gcaatggtaa aaactattgt tccatattcc ggcgtgtgca gatagctggc
     6241 ttcaaaggcc ttatacaggg ctttttcaag tgttaaatca gagcccatga cttcacctgt
     6301 tgatttcatc tcaggcccta aaaggctatc caccttagca agctttgcaa atgagaaaac
     6361 cggcgccttg atatggacaa gcgagctttc aggataaagg ccatcttgat agcctaagtc
     6421 ttttaaggtc tgatccaaaa taagcttcgt agcaacttgt gccattggaa tattggttac
     6481 ttttgataaa aatggcactg tccgactagc acgaggattg acctcaatga catagacctg
     6541 ctcgttttgg atcacaaatt ggatattcat catgccaata cagtttagcc ctatagcaag
     6601 acgcttagtg taatcaacaa tcttgtcttg aacctgttta gacaggtgct gcggtgggta
     6661 cacagccatt gaatctcctg aatgcactcc tgctctttcg atatgctcca tgatccctgg
     6721 gattaagact gattgaccgt cagagattgc atctacctcg cattccttac caacaatata
     6781 ggaatctatt aaaacagggt gctcagaact agccttgata gctgttttca tgtaggaaag
     6841 caaatcatct tcgttttcaa cgatttccat tgctcggcca ccaagaacat aagagggtct
     6901 gaccaacacc ggaaagccaa tagcacgcgc tgcctccaag gcctctgcct cattagtggc
     6961 tgtttgccca ggaggctggg gaattcccaa ttccttcaag gctttttcaa agagcttcct
     7021 atcctcagcc cgatctaagt cctctagctg tgtgcctaaa ataggaactc cggcctttgt
     7081 tagctgctct gctagattaa tagcggtttg tccgccaaac tgtaggatca ctccctttgg
     7141 ctgctctaat tcaataacat tcatgacctc ttcaaaggtt aagggttcaa aataaagctt
     7201 gtctgatatc gaaaaatctg ttgacactgt ctcaggattg gaattcatga taatggcttc
     7261 atagcctgca gcctgaatgg ccttgacaga atgtacggtt gcataatcaa actcaactcc
     7321 ctgaccgatg cggataggac cagagccaag gacgataaca gattctttct cggatttgat
     7381 tgactcattt tcccactcat aggtcgagta aaaataaggc gtttgtgagt caaattcagc
     7441 tgcacaggta tcaaccatct tataaactgg caagacacga taagcccgcc ttaaccgtct
     7501 aatacttgca gcatcagtct gccaaagctc tgcgattttt tgatctgaaa aaccatatcg
     7561 cttggcttct gtcaacaagt caatgtcaac tggcttttta acaagctctt gctccaattc
     7621 tacgatatga cgtaatttat ccaaaaagaa taaatcaatc ttggttaagc cagctagctc
     7681 ctcaatactg tagccacgac ggagggcctc agaaagatag aatagacgat cgtcctgcgc
     7741 ccttacaatg tgagcaacca gctcatgatc actgatagta tctagaccct tcagttcgtt
     7801 atggtgtact ccaatttcca acgagcgaca agcctttaag aggcattcct caatgcgacg
     7861 cccaatagcc ataacctcac cagttgcttt catctgggtt cctagacgac gctccccctg
     7921 ctcaaacttg tcaaatggaa agcgtggcag cttggcaacc acataatcaa gagctggttc
     7981 aaacatggca taggtggttc ctgtgaccgg attaagcatg tcatcaagcc ttaagccaac
     8041 tgcaatttta gcagctattt tagcgattgg ataaccagtt gcctttgaag ccagtgctga
     8101 tgagcgagat acccgcggat taacctcaat cacataatag ctgaagctat tggggtcaag
     8161 tgccagctga acattacagc ctccttcaat cttaagggca cgaataattc tcaagctagc
     8221 atcacgaagc agttgattct caacatctga tagggtttgt gtcggggcaa aaacgattga
     8281 atctccagtg tgtatcccta ctgggtcaaa attttccatg ctgcaaacaa ccagcgcgtt
     8341 atcagcagca tcacgcataa cctcatattc aatctcttta aagccggcaa tggagcgttc
     8401 aatcagacac tgggtgacag gagatagctt caggccattt tccacaatat ctcgcaaggc
     8461 ctcttcgttg gtgcaaatac cacctccagt acctcccaaa gtaaaggccg gtcggacaat
     8521 gacaggatag ccaatggcat ttgcaaagct gatagccccc tctactgtcg tcacgatctc
     8581 tgattctgga ataggctctc ccagctcttt cattaattgc ttaaataaat cacgatcctc
     8641 tgcctggtca atagcagata agggtgttcc aagcagctcg actcctaatt cttgtaaaat
     8701 accagcctta gacagctcca tcgccagatt aagaccggtc tgaccaccta aggtcggtag
     8761 caaggcatct ggtctttcct ttcttaagat acgactaaca aatgccagcg tcaggggctc
     8821 aatataaacc ttatctgcaa cctctttgtc tgtcataatc gtcgcagggt tagaattaac
     8881 cagaacaacc tgatagccct cttcctttaa ggctagacaa gcctgtgttc ctgcgtaatc
     8941 aaattcagct gcctgcccaa taacaatagg accagaccct atcaccatga tttttttaat
     9001 atctgtacgt tttgccataa tatctggtac aaaaggcctt aacaatccga ataaaataag
     9061 tataagagcc caacataaag cttcaaaatc tatttgttac taggatttgt gcctatactc
     9121 gactgcagcg agcctcttgt acctactcct ttcattattt gccgtctcac agggcggcat
     9181 taaataaaac acttaacagt ctgtcacatg agacgatgag tacaagatca agtaaccctt
     9241 agctcagcaa gtatagatga cttaattgat atagtccttt tacttctaaa gagggcgatc
     9301 ttgccagcaa atactagcca taaccagcgg cagagcgatc atttcctact agtctatctg
     9361 ctgcctgact caagctgttt catgacagct gatcaagctt ttggtgcttg ctttttgatc
     9421 tgctagcaca cttgattaac atttgccttg ctgctctagc tgccaggcgt caatcatatc
     9481 taaaaattca tcaaatagat agctagcgtc atgagggcct ggtgcagcgt ctgggtgaaa
     9541 ctgcacagaa aaggcgggaa catgtcgatg tctcacccct tcaacagttt tgtcattaat
     9601 ctcctcgtgc gtaaccatca agcagtctgg caagctgtcg cgctcaacag cataaccatg
     9661 attttgacta gtaaaatcaa tacgtccagt cgctatttct ctgacagcat gattaaagcc
     9721 acgatgtcca aaaggcattt taaaggtctt agcgccatta gctaagctaa gcagctgatg
     9781 acccatgcag atgccaaaaa tcggaatttt cccttgaata ccacgaatca tctctaaagc
     9841 ctctggcaaa tcctctggat tacctggacc atttgatagc attagaccat ctgggttgag
     9901 ctgtagaatc tcttctgctg tgatatcaaa ggggactatt gtcatctgac attgcctttt
     9961 ggataattct cttaaaatgg aatgcttcaa gccaaagtcc accaaaacaa tatttttccc
    10021 aacacccgga gcgggatagg cagtcttagt tgacacctgc tcaataccat tagtcggaag
    10081 cacagttgca cgcagctgat cctttaggtg ttcaagcgta tcaccatcat ctgccattgt
    10141 tgccttcatc gtaccatgct gacgaatgat tttggtcaac gctctggtat caattcctga
    10201 aatgcctgga atccccttat gctttaaaaa ctcgtccaag gtcatttgct gacgccaatt
    10261 gctagctatc ctgcttactt cagagacaat gacccctttg caagttgggg caatggactc
    10321 ataatcatca cgattaatac cataattacc aacaagggga taggtaaata ctaagagctg
    10381 cccgttatag gactggtctg tgattgactc ctggtagcct gtcattcctg tattaaagac
    10441 aatctcgcca gtgacatcaa tatctgcacc aaagggcttt ccttcaaaaa tggtgccatc
    10501 ctctaagata agtaaccgtt ttgccatttt aaccccctct aacatgcctt tagaccttat
    10561 cgtttctgcc attaaggatc gcttcaataa tggccatacg gacaaagaca ccattagcca
    10621 tttgagctac tattcttgcc tttggagcct ctactaaatg gtctgcaatc tctacatcac
    10681 gattaactgg tgccgggtgc ataataatcg cagagtcctt taattgcctg tagcgctcct
    10741 cagttaaacc aaactgtcta tgataatctt cctttgaaaa gctttgacta ccatcatggc
    10801 gctcatgctg cactctaagc agcatcaaca catctaattg atcaataata tgatcaatcg
    10861 ccatgtactt tccatagctg tcaaattcag acgaatacca ttgctcaggt ccatagaaat
    10921 aaagctctgc tccaagccgc tttagaatct gcatgtttga tttagccaca cgagaatgtg
    10981 tcaaatctcc tgcaatagca atctttaggc catcaaaatg accaaattct tcataaatgg
    11041 ttagcaaatc aagcaagcat tgactagggt gctgacctga tccatcacct ccattaacga
    11101 tagaggcagt aatcgttgga ctgtcaataa gctgctgata gtaatcatct tctgggtgac
    11161 gaatcacaca gatttctgtt cctagagcac tcatggtaag aacagtatca tataaggttt
    11221 cacctttatt gacagcactt gtatcagcgt taaaatcaag gactctaaga ccaagcttat
    11281 tctcagcaac ctcaaaggat ttatgggttc ttgttgaatt ttcaaagaat aaattagctg
    11341 caaagtgcct actgttatct ttaatagcta ccttacctgc cttgtattca gagccacgac
    11401 taataagtcc taaaacctct tcatttgtta aatgctccat tgacaccaaa tgcttaagcg
    11461 caacacgatt atttacaact gacatgattt atcccctttt accaataatg aaatgatgat
    11521 aacaattgac aacagctaca gactagtttt ctggaagaag ctgatataat ataatgccaa
    11581 gaagcgttga aaaagcaaca cccgaaatct gaaggccgtt gatttgaagc atgaggcctc
    11641 caataccaga aaccagaata acactagcaa tcaataggtt tttcttgttg tccatatcaa
    11701 ccttagcttc aatcaggatt ttcaagccac tagaggctat aaccccaaac agagcaatcg
    11761 aaatccctcc aatcactgga gtaggaatag actgaataag tgctgatacc ttaccaacaa
    11821 agcttaacag accagcaatc acagcggcac ctgcaataac atagactgag aagattttat
    11881 tgagggccat cacaccaata ttttcaccat aagatgttac cggaggcgct cctaaaaatc
    11941 cagcaatcac ctgcgcaagg ccatcacccg tcaaggtttt ttccaagcca ggatccttga
    12001 aataatctct tttagtcagg ctattaagca ccatgatatg accgaaatgc tctgtcatgg
    12061 tgacaaaagc aatcggagcc atcgttaaaa tagcgctagg atacagggta atgtcatagg
    12121 ttaaaaaggg gatagccaca gctggcacac tgagccactg agccttagcg acctgtgtaa
    12181 agtcaacaat agactgaccc gtcaccatac caacaagaat cgcaaacaca tagccaacca
    12241 acaagcccaa caaaatagga atgatggcga caattccctt gccataaatg ttaaagaaaa
    12301 taatcgctaa caaggtgaca agaccaatca aaaggtatag caggttatac tttccatcct
    12361 ttagcatgac atcactaact gctgttgagg ccaagctaag accgatcacc ataacaatgg
    12421 gaccaaccac aactggaggt aagatcttat cgatccattc atttccaatc gccttcacca
    12481 ccaatgctac aaccagataa accaagccac ctgtaattgc tccctgtgca actgccccaa
    12541 tgccatctgt tttcattagc atttgcatgg ctgcaatata agcaaagctt gagcccatat
    12601 aagcgggaat tttaaatgtt gttactgaca aatgcgccag agtcccaagt ccacttgata
    12661 agagggcaac tgacggatca atcccaacca aaattggaac caaaacagtt gctccaaaca
    12721 tagcaaataa atgctggaag gacaagccaa gcaaaatccc tgcctttggc acttcttcta
    12781 catcataaat gacatctttc acacaatcac ctctttctta ttccggatca acaatactaa
    12841 tacgatcttg accgtcaacc tcaaccactt caacgacaat ctcttctgtc ttgcttgtgg
    12901 gaatattctt tccaacataa tcggcccgaa ttggtaattc acgatggcct cgatccacca
    12961 aaacagctag gctaacacgt ccaggacgcc ctaagctaac caaattgtcg atagctgccc
    13021 gaatcgttct gccggtataa agcacgtcat ctactaggat aatatccttg ccggtaatat
    13081 ctaccggcat gctggtagtg tcctcttcca ctctcatgtc atctctgaag ggcttggtat
    13141 ctagctctcc aactgccaag tgcaggcttt ctagctgctc taatctttct tgaatacgac
    13201 gagcaaggta aacacctctt gtcttaatcc ctacaagcac tacattatct agttgcttgt
    13261 tgcgttcaat aatctcgtac gtaatccgcg tgatcgcacg cttcatggtt agctcatcaa
    13321 caattacctt tgatttcatt caaggcctcc tcaaaaaatt caactaaaaa aatctccctg
    13381 ttaacaagga gattcagcaa aacaggcaca caactagaca taactgtgca cttttttatt
    13441 cagaacatgc tccttgccag cctcacagga ctgttttaaa ggaatatttt atttttatca
    13501 gtatagcaaa atcacaagct aaaaacaaga attttttaaa aaataattca aaatatatgg
    13561 agctattaca gcacaaagga aaatgccact aaagtcatca gtaattgttc agcacaattc
    13621 ctaaaatagg tctttagacc tattgcgttt gtaccaaaac aatagtacaa tgatatcaaa
    13681 cacaaaggag agcgtttatg atgaatgata taactagaaa gattaaccat aagcaactga
    13741 ttcaagtcac taccattcta ggcattattg ttaccatcgt tattttgttc tatctgcagc
    13801 agcaccctaa tctttttgca gttggcggtc cttttcagac ctatcttatg gaacttggta
    13861 tcctagcccc ctgtttgttt atactgcttc aaatcattca ggtggtttac cctatcattc
    13921 ctggaggctt gacctgtgtt ttagggcatg tagtctttgg gccattttgg ggatttctgt
    13981 acaatacact aggtattttt attggttcgt tgcttagctt tatgcttgcc agaaaatatg
    14041 gtgaacagtt tgctaaagcc tttgtatcag atgataccta taacaaatac atcccttacc
    14101 tcaataaagg caagtatttt gaacgatttc tcataacagc ctttattttc cctggttttc
    14161 cagatgattt tctctgtatg gtagctggac taagcagcat gtctgtcaag aaatttatta
    14221 gtattttctt gatatcaaag ccaatcactc tttatatcta tacccttctt gcttaccaag
    14281 ggatacaaat cgttggacag gtattgcaat cctaaaaaag ctagtattaa gctatcaagc
    14341 ctggttggaa tacagtattc caatcaaaaa ggcgctcagc ttagtaccag ctttttatcc
    14401 ttgtcttagt tgctccaaag tcctttggaa gatttctggt ggctcaacag taaagaccag
    14461 ctcctctcct gtcacagggt gggttagtcc taatgtttgc gcatgaagaa actgcccatt
    14521 gccagccaag gtcttacgag gaccgtagag cggatctcct gcaagagggt gaccaatata
    14581 agccatgtga acacgaattt gatgagttcg acctgtttcc aattgcaatt ccactaagct
    14641 gtaacggcca aagcgctcca agaccttaaa gcgggtcaag gcttccttgc ccttagcagt
    14701 tacagtctgt tttttacgat ccttgtcact acggccaatc ggagcttcaa taacacctcg
    14761 atcctttggt aaattaccat gaacaatggc cacatacttt cgtaaggatt tcttagcctt
    14821 aagctcatca gctagtagct gatgggcctt atcagtcttg gcaaccatta aaaggccaga
    14881 ggtatcctta tcaattctat gcacaattcc tggacggata acaccattaa tagaggacaa
    14941 gtcttttacg tgatagagca aagcattgac cagcgtccct gtagaatgcc ctgcagaagg
    15001 gtgaacaacc attccctgag gcttattaat aatggccaat acatcatctt ggtagacaat
    15061 atctagtggt atatcctgag cctgatagtc caagctgctt tcctctggaa tatgatagct
    15121 aatgcaatca ccgacctgca caatatactt ggccttctta ggtgagccat tgaccaatac
    15181 ccttttttgc ttgatctgat cattagcctg acttcttgat aatggtgtca aatcagccaa
    15241 ggccttatcc aggcgatgac ctgattctgt catcttaatt tccatagtcc tcttctttcc
    15301 atagacaaat gactaatagc aaaacaccta ccgtcaaata agaatctgcc acattaaaaa
    15361 tagcaaaatt gatcacatct aaatgaatca tatcaaccac ataggataac ctcatacggt
    15421 caataaaatt cccaagacct ccagatataa tcagcaataa agagagctgc agccaaaagc
    15481 tagccttggg gtgcttcagc acataataaa tggcatagcc aaccaccaaa atagttatga
    15541 ttgtaaaaaa ccactgttga ttctgtaaga ttgaaaaagc tgctcctcga ttttgaagat
    15601 aggttaagct caccaagcct ggtataaagg gcttcacctg ccctagctca atatgtgtaa
    15661 cagtccacca tttacttagc tgatccagta tcattaagac aatggcagct ataacaaaac
    15721 taattctttt caactaatcc tattcctttc agcttaaaaa caagagatta ccttaatggc
    15781 ttcaaaagag caacaacagc cagcaacctc tatagcgtac ttaacctcaa agcctccaaa
    15841 gagctggtgt gctaatagtc ttttagcatc atttatagtc aaccacacag cagctctaga
    15901 cttgacctta taccaataag tctcgccaca gcagctcgct taagtcgtat ccaggccaga
    15961 gctaagtcct gttgtctatc gtttactttc tttttcgatg ctcaaaataa tcctgtaaaa
    16021 tggtcacaaa atgtaaagcc gcagcagata ggttcttatc cctacgtttg acatagatca
    16081 ttttatgctc catatgatca cgcaagggaa taaccttaat gccattaaca ctttgctgat
    16141 ctaaaaatcc agatcctgtt gcaaaggcag ctgtcctttc taaaatgcca tttaaggttg
    16201 ccctgtctga cacagtgtat atatgagggc tcttgcttgt atcaataaaa ttttctgaat
    16261 aataaagata ctcttccttt tcttgagtaa agcgtactgc tggtaaccct tgcaaatcct
    16321 ctaagaaaag ggctttcctt tgggccaatg ggtggctttt tgataggtaa atgtgggttg
    16381 taaaggacag caattcaaca taatccaaag ccagcttatc cattcgctga aaaagcccct
    16441 gacggttttg tgcattaaga tagataatcc caagctcact atttccctgt gccacctcat
    16501 ctaaaatttg catcgtcgtt gactcaaaaa ctctgaaaac cttatgccca tcatgctttt
    16561 gggcaaatga cgttattaag gctggtaaaa aatcataatg ctggctcgca actgaaaatt
    16621 catttggctc taaagccgat tgagaaaact ccttttccag tgaatcaaag cacttaacaa
    16681 cctctaaggc tttttcataa aataaaagcc cctggctggt taagacagtt cctgttgttg
    16741 tcctacgaaa gatctgaaag ccaagctctg tctctaaatc cttgactgaa acagacaaac
    16801 tgggctgact aacaaatagc tttgaagcag cctcacgaaa ggtaccatta tttgcaatag
    16861 caaccacata tcgtaattgt tgaatattca ttaatccact tcctaaatct agtacccttc
    16921 attataccat aaagctagct aataaaaaac aaaggcttcc gtcctgacca cgacaaacgt
    16981 atgtacagat aatcaggaaa catcattgac tttttcaata gtgttctatc atatttagct
    17041 atagaaaaca gccttactat aagttatact tttgaaagaa gtaagcctta aatcacaccg
    17101 agatttttat gggctatccc gtctgtccaa ggactgagga ttggctacat ctagctaaat
    17161 aagccatttc gggattttac tatctagaag tacttataga caactattac agtaaagtag
    17221 cgtcacaata taaaaaaggc tatcccaaag tacagaacag ccttatatca tgccttttta
    17281 gcacattatt ttgcgattgg gtatacagaa acttgtttct tatcgcgtcc tttacgctca
    17341 aagcgtacaa caccttcaac cttagcaaaa agagtatcgt ctccgccacg accaacgtta
    17401 acaccaggat agatatgtgt gccgcgttga cggtaaagga ttgagccgcc tgaaactgtt
    17461 tgtccatcag ctgctttagc accaagacgt tttgcttgtg aatcacgtcc gttagaagtt
    17521 gaacctccac cttttttgtg ggcgaagtgc tgcaagttag aaagattaag tttaaccatt
    17581 tgaatttcct ctcgttgaat ttaattcatc acaggctttt gaacatattc tgatgaatgc
    17641 tctgctaaat tctctaagcc aatcacaaca gactcaaaga gaatttgcca tacctgctct
    17701 tgttgttcag taaatccctc aggctttgtc acccttagga atccaccatc atcgacgatt
    17761 tctagtgctg gctcaagacc tgtcatttgt tcaatcgaat taacaagatt gaaggccaaa
    17821 actgaaaccg aagcacaaac tacatcaaag ccgtactcac cgcttccagc atgtcctgtg
    17881 ataagcatct cagtccagcc agctgcgtct tttgttaacc gtactttaat catgtcaaac
    17941 tagaattatg ccttgatagc gttaatcaca actttagtgt aaggctgacg atgaccttgc
    18001 ttacggtggc tacctttttt aggcttgtat ttgaaagtga caactttctt ttgttttcct
    18061 tgcttttcaa cagttccaac tacagtagct ccctcaacaa ctggagtacc aacgacagtc
    18121 ttatcaccac ctacgagaac aacctcgtta aaagtgattt ctgcgccagc ttcagcgtca
    18181 attttctcaa cgtagattgc ttgacctact tcaactttaa cctgttttcc accagttttg
    18241 atgattgcat atgtgctcat gatgcacctc ctataagatt tttgatgagg tttccctctg
    18301 tgaagactcg cctagaatcg tgagagccaa tctacttgaa aacgattttc gtgcggttgc
    18361 acaggacgtg cacttagtca acgttacaat tttaacatca aatttggttt ttatcaagaa
    18421 aaatatgctt ttatcttcct aaaatcttaa gctatacata gtcacagcca tgtaaaggct
    18481 agcaatgctt taccatttta ggttaaccag ggcattcatt tctttataag caatggctgc
    18541 tttttcttgc gtttcgggat caatcttatc ataatacctg ccgcctttga taaagtcctc
    18601 caaaaccatg gtacgatagc tatatagctc atagccttca ctaccataga ggcccttagg
    18661 cttagctaaa accattgtcg ggtgagcctt tactgttttt atttttgttt tttgcccctt
    18721 cttctcaaag gtaaggtcca ttagcacgcc gcgctctgtc caaatatcat caacagtctc
    18781 taggcgttgg ttggaaatga aattacccat tgaatagata ataaatttct tttccttgtc
    18841 cttaacaatc gtctctgccg gctctacaac gtgggggtga cctcctaaga caacatcagc
    18901 accccagtca atcatttttc gataaagagt tttttgctca gctgttggtt ctaaagcata
    18961 ctctgtgccc atctgcggca taacaatggt aatgtctgcc tctttttcag cacgtatgag
    19021 gtctttttgg attctgtcct cattaaggtc agacaggtgc ttatcatact cctcctgact
    19081 gagtgtagcc tccattccat tatagccata tgaatagccc aatattgcaa tcttaatccc
    19141 attaaccttt ttaatgagaa tgttctcctt agagcgatcc tgctcataaa taccaatgct
    19201 gtctatcccc atatcagcaa aaacacgctt ggtattgaga gctccctcta atcttgagtc
    19261 caaaatatgg ttatgggcca aatcaaccac atcatagcca gtatgcttaa gcgcagctgc
    19321 aatagcctct ggcgcattaa acaaaggata gccagctaga ggatagtctg gactgatcgt
    19381 tccctcatag tctccaatgg ccaaatcagc ctgactaatc caatccttca catactcaaa
    19441 atagggatta aaatcatagc taccatcagc ctttttagca ctcatataga gaatatcatg
    19501 aatcaaaata tcaccatttg cgacaacacg cgctgtttgt gtcttttgag gtgtcttgct
    19561 tttcgtttgt gtgccttttt tgggcatgcc caacaaatca aaagctaacg caaaagcaag
    19621 tgccgcaaca atcaaggtaa gcactgaaag catggtcttt ttatattgaa aatcttttag
    19681 caagtgtcaa acctcctttt tgtctattat accatgttga cacgactttt tagtaacaaa
    19741 tcccaaagaa aagattatgc ccatttgaga agaatgcctt aaacagcaat ataggttcgt
    19801 accaactagt caaaagctgg agtgctcctc tttgcttgat gtcatatact tttagcctaa
    19861 atagctttca acaaagtcta atagttgaat aatgtcatgc aaaatatggt ataatgaaac
    19921 aaaatcaaac tagtcaggat agtcacatga agcataactc tttcagccgc tcactattac
    19981 tcccccttct catctgttcc ttgtctgctt gctcttctca tacagagaaa aaagaccata
    20041 ccaaagacgc tactgctatc accgataccc gaaaagcaga gcatcaggac atcagggcaa
    20101 atatggaaaa ggtcaagctc gctaccgcta gcaccgactt caaaggtggc tcaagccttg
    20161 aggaactaat cgctattttt ggacagccta gtcagcacga agaaaaagcg gccggtagtg
    20221 ttactcttga ctcctacaca tggcagtttg accatgttac ggttaatatt aacctctatg
    20281 aaaacagcag cattgttaaa actattgcta actttgcttt tattagagac ctggccttat
    20341 ccttaaagga ctacaacagc ttgaaaaagg gcatgaccta tgatgaggtc aagcagctat
    20401 tgactgagcc tgacaattac agtcaagcca attccagtga aaaagaaacc attcaagcca
    20461 tttggattag tggcttaaaa gctcagacac agggtgccaa tatagcacta acctttgaaa
    20521 acaaccagtt gacagaaatg tcacaggttg gtcttgaaga ctagtcttga aaagcacaat
    20581 aatcacatta ctgataagaa aaagagcttg attattaata agatcaagct caaacgatag
    20641 acccagcagc tgctgacctt gacagtaata tgtaacaagc tgagctacta ctcactaggc
    20701 agtatttact agcagccact gaatttcctt tatgatgaca ggcaaccacc ttttttgtgg
    20761 tgacctgtca atagcaccat aagctctcat tttaccagat agctttgctt aactctaagc
    20821 gtatgatgag ctttttaggt tgtctgatag tataacatct aacccctagt tgatgatgta
    20881 gataaagtaa gagctgctaa agatagcacc ataaataaga tccaacatag ggtcatatta
    20941 tatagtgcca agaacgaaaa aataaagaca cctacaggga gtgataaaga gaacagaaga
    21001 cctaaaaagt tattgctttg ggctagcata tctgatggga gattttccat taaaagggcg
    21061 tccagcttgg gtgtggcttt tcccataata taagctgcaa aggctaagca taaaacccct
    21121 atgatggcag gtaattgcat agcattagaa gctcctacca gcaaaaatgc tataccctgg
    21181 gtctgtgcta gctttgatat tgaaagcctt gaaaagtaat cctttggtgt tagatttccc
    21241 aacatcgctc cgataatcgt aacggcatca acaataacta tagactgccc ataatgaaaa
    21301 tgaaatagct gatgatccat caaataaaaa tgataaatgc tattaattgc tcctccaata
    21361 gcgtttaagg tcaaaatgga taagagtagc tttacaaaag agacatgatc agtcttttta
    21421 aaggtctctg tcatgcttgt atacattacc ctaaattgct tcattaatga aacacctact
    21481 tcagaagctt caacgacatc atgccttagc ttttgccgat ttttaagaag cacaacagat
    21541 gacaacaaaa aggaaatagc atttatcaaa gcaacaaagg cataattgtt acctgatgtc
    21601 gttagcagcc aaactcctaa agcctgtcct gcaatactag agaggtagcc gataaattga
    21661 gaaaacgaat aggcctcata gagcttttct gattcaatat ttttctgcat tatcgggaga
    21721 cgtaagccat ttttgtaatc acttagaata tcagaaacca cattcaaaaa gcccacaaag
    21781 gcaaatacca agaacgtctg gtttgtcatc aacaaggcta caatcgtaaa taaaagagat
    21841 tgtataaaac caataataat aagatttctt gttttccgcc ttgtcttatc tgctttgacg
    21901 ccaatccaaa aggtaaacac cataggaatg atggtgatga tattggctat aaaaacagca
    21961 atatgagaat aaggcagcgt ggttgcataa ataataaaaa caatattgta aatataagag
    22021 cctaaagcac ttaaaaagtt tgaaactgtc agcgttctaa aaacgacatt tttaatcaat
    22081 accctcattt ggttacctgt tgacgtcctt tcttagttga ttgttgcctg cttagctagt
    22141 gaatacactc tctatatatc taaagcttgt cagatccata tgcttcacca tgtaccagct
    22201 gaataaatgg gtacttctct ggatgctcta tgattgtctt aactttcttt tccacgtagg
    22261 cttcaaagct tttttcaaag ctacttgaac gctcacgaga atcttcttta tagatacatt
    22321 ttttagtaat ccttggtttt ctcataacaa tacatctcct cagtcttttt agtaggacta
    22381 gttactaaat tatggtttgt agattgtaca tttccaagtc acaacaaagc ctttcactgg
    22441 cgcaaagcat ctactagcct cgtatacaaa tggagtcatg tttgtgatct cctttcattc
    22501 ttgatgagtc tagtgtatca tcaaaaaccg caccaaagct aaactgttca taagttcaaa
    22561 tcatggtttt gacattaatc aaaaaacagt agctcaaaaa gccactgttt gctgctagtt
    22621 aaacatctaa acattttttg cttatcaatg ctttagattg catttattca acttccttta
    22681 accatttctc taaactatct gaataatagg ctgcactttc atcacaattt aatgtcttta
    22741 agatgtgtat ggcgtcattt atttgcttta agcccagttc cttttcccct ttacaatata
    22801 ggtgctgacc atcagcaatc atataaacaa ttcttaagta ggtgtcattt tcctcaaaaa
    22861 aaatgattgt taatcatgtt atcaaaatat gcagctatac ctagcctttt ttcctgagta
    22921 gctttaaaca gcccatttaa taaaatgctg tgcactaaat ttcgatgctg ccaaagctcc
    22981 tcaaaaaagt ctactcttcc tagcatttct cgagtatacc gcaaatacac atccaaggat
    23041 aataagggag aaatatctga aaataattgt aattcgtata ttccccaaat ctccactgaa
    23101 aacaaataat catataaaaa gctttgctca tctggagtca ttttgatatt ctcatctaaa
    23161 aagagcattt gacttttaat catcaaagca tttaaaaaat agatatcctt tttgtataaa
    23221 tgatactgct ccagctcttt tgtatacaat tgatgtaagc tgaacaggtc tttttttgat
    23281 atggcctccc agatctcttg ctttaggaca gcatatgggg aaggcttaaa gccatttgct
    23341 agataaacaa attcattcag ctctgtccga atattgctga gtccaaccaa tagctttgag
    23401 attgttatat cggattcgcc attttcaaat ctgcttaaca tcgaatgaga aaatgcatct
    23461 cctgtcgctt cctttaaaga tatgtgtcgc gatgtccgca gtaatttaaa catttctccc
    23521 atatattgca tgtcaatacc tctctaatct ttcattttag tatagtatat aacctcaaaa
    23581 atgtaaatct agtcctgatt gcataagcct ttaattcaac gtttggtgct actaaatatc
    23641 ttatttttcc gaggtaaagc ctcagcttta tgctataagc acttgctgcg ttttagaaaa
    23701 tgggctaaat cagctatatt cctttttaat aacaaaaaag ccttatttat gtactg
//
LOCUS       DARYSY010000033        23729 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYSY010000033 DARYSY010000000
VERSION     DARYSY010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23729
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..323
                     /locus_tag="TVR04_001214"
     CDS             <1..323
                     /locus_tag="TVR04_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269910.1"
                     /translation="PEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPM
                     PDPAPKPETKPQKPTKPSNATSQSSGKALPKTNDTGSLMTALGTGLLSLLGLGFLSKR
                     KRKQ"
     gene            complement(489..1082)
                     /locus_tag="TVR04_001215"
     CDS             complement(489..1082)
                     /locus_tag="TVR04_001215"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1269911.1"
                     /translation="MSKIIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQAKGG
                     RLYQVLLETFGQDILLPSGELDRPKLAELLFAHADSMAKSSQQQNAIIREALATKKEQ
                     LAQTEDIFFMDLPLLVELGYQDWFDAIWLLYVDDNTQLKRLMERNQLTELAAKQRIAS
                     QLPMSQKKVYADVVIDNNGDLQALEAQISKALQDLEA"
     gene            complement(1082..1900)
                     /gene="mutM"
                     /locus_tag="TVR04_001216"
     CDS             complement(1082..1900)
                     /gene="mutM"
                     /locus_tag="TVR04_001216"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1269912.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVKVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDLGQLVMISHLRMEGKYLLFSDTVPDQKHFHVFLTMTDGS
                     TLVYQDVRKFGTFELLPKSELAAFFQKRQLGPEPTKQAFRLKPFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPERRSASLKKAEIKRIHDEIIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGAAIVKLKVGGRGTHVCPRCQR"
     gene            complement(2375..4174)
                     /locus_tag="TVR04_001217"
     CDS             complement(2375..4174)
                     /locus_tag="TVR04_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1269913.1"
                     /translation="MNLEPFQISDQFYLDGRPLQILSGAIHYFRIHPDDWYHSLYNLK
                     ALGFNTVETYIPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWE
                     FGGLPAWLLTKNCHIRSSDPAYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYG
                     SYGEDKAYLKAIKALMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQEN
                     FADMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEELADAVMEVLAQGSINLY
                     MFHGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAQFPEL
                     ESTLPLLKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTH
                     LLKDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIEN
                     MGRVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPG
                     FYHYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLND
                     IVIFETEGVYQDSIRLVDKPISLDCLQSDERNS"
     gene            complement(4290..8930)
                     /locus_tag="TVR04_001218"
     CDS             complement(4290..8930)
                     /locus_tag="TVR04_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1269914.1"
                     /translation="MFFNRSGQEQVRRYAIKKLSVGVTSVCVGIGLAVCLPVAVFAED
                     MSEASPQPPIEAVVTDTSNDQELHLETSESLDVSEAVKASEVVVIDMVASNDPAVNQA
                     PDQADQKAPVDLNKVTDGSFDHQYVSNKTQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEAATPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKFSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWEDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLENGNLVLNVTERKGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYVKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDERLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSIENEYLFTNKGGNTNATLQASGRNDLAA
                     LSELAPGIYNIYYSAVPEAANLGSTVTPTAKIAREVAILTVLPKEGLYGQKGEPLSTV
                     ALPTNWQWVEPEELLGSADRYQVKYTTEGGRAVYTTIEASYIADQPSSDEQSILVDLG
                     NAILDATAEKAAVTDDEVLSKLDDVMSLNQGTVTIRYRLDTADTTVRSASPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTVTVGGLSRSYDGESAFHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLVAAADA
                     RKKHYNDWGDIATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQNGHQTDMYVDEGNFETAFSTRGNLYRTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGATWGDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSINWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEKVTITSVAPKQNDTATLTIQVTFNQPMFILGDRQLAVTVDGVEKTASYVLGNGT
                     DTAIFELSLDSMPEEPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPDPTTA"
     gene            complement(9105..10463)
                     /locus_tag="TVR04_001219"
     CDS             complement(9105..10463)
                     /locus_tag="TVR04_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1269915.1"
                     /translation="MNNYMNFLSQKLLPIATKIGNQRFLVALRDSFIATMPVVMTGSI
                     ALLINAFLVDIPDQFGLQGITEAFQWWVTINNLVFKGSISIVSLLFVYCLGVNVAKLY
                     KTDTLSSGLVSLAAFVIAIGDSVTSSIDASGLKGVDLVTAFKDSGVTVSGSSLNVTIS
                     GLLPGAQINSNGYFTAIIIGFLASIIFCKLMLKNWTIKLPDSVPPAVAKPFLSIIPGF
                     CALYSVAILTFVFEKLTGSLMIDWIYKVLQIPLLGLSQSFIAVVLVAVLTQFFWFFGI
                     HGGNVMAPIMEGVFGVALLANLEAYQKHEAIPYLWTSVSYGAFVWYATLGLLIAIFWK
                     SKNEHYREVAKLGVAPVLFNIGEPVMYGLPTVLNPLLFIPFIVCPAVMSSVAYIATSL
                     GLVAPVTQNVTWVMPPVLYGFFSTGFDWRAIVLSLVNLALATLIYLPFVKMADNELEK
                     AG"
     gene            complement(10528..11844)
                     /locus_tag="TVR04_001220"
     CDS             complement(10528..11844)
                     /locus_tag="TVR04_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1269916.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEVWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVPFVDESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYVDLGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTTNEG"
     gene            complement(11837..12169)
                     /locus_tag="TVR04_001221"
     CDS             complement(11837..12169)
                     /locus_tag="TVR04_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1269917.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADEALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(12179..12496)
                     /locus_tag="TVR04_001222"
     CDS             complement(12179..12496)
                     /locus_tag="TVR04_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1269918.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLQADIFALPLTEA
                     GDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(12520..13419)
                     /locus_tag="TVR04_001223"
     CDS             complement(12520..13419)
                     /locus_tag="TVR04_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1269919.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KDYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALIMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            13599..14801
                     /locus_tag="TVR04_001224"
     CDS             13599..14801
                     /locus_tag="TVR04_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1269920.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQVDPSISSYYKADYISELIQVFLKQHKHYSVQAIGIALPGHYDHSISSSTHINT
                     NNPIWQQVDLTAIAKSFSIPVVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPAGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PHSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(14964..15440)
                     /locus_tag="TVR04_001225"
     CDS             complement(14964..15440)
                     /locus_tag="TVR04_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1269921.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNAETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(15751..17082)
                     /locus_tag="TVR04_001226"
     CDS             complement(15751..17082)
                     /locus_tag="TVR04_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1269922.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLSWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVASILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDQKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLNHKNGFKQTFITVFGSTLVAESIIILTSLFF"
     gene            complement(17174..17953)
                     /locus_tag="TVR04_001227"
     CDS             complement(17174..17953)
                     /locus_tag="TVR04_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1269923.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADCVLCDVTDEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAADLGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(17983..18627)
                     /locus_tag="TVR04_001228"
     CDS             complement(17983..18627)
                     /locus_tag="TVR04_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1269924.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFIVTPEGIAVEEIHPDYTFEEVQEVTEARLICPN"
     gene            complement(18633..19283)
                     /locus_tag="TVR04_001229"
     CDS             complement(18633..19283)
                     /locus_tag="TVR04_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1269925.1"
                     /translation="MNKRISMEEAVNLIKDGDTIMVGGFMTNGSPERLIDALVAKGVK
                     HLTLICNDAGFPDKGVGKMVAQHQFQKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAEITIVEARDIVPVGAIEPIAVQTPGIFVNYLVEGE"
     gene            complement(19298..20488)
                     /locus_tag="TVR04_001230"
     CDS             complement(19298..20488)
                     /locus_tag="TVR04_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1269926.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKTVSAVQLGKVVVEALLEKSG
                     LKPEQIDEVIFGNVLHAGLGQNVARQVAITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSEIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDTFALASQEKAAAAQAAGRFVDEIVSVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALRPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     MGVIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNADIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            20680..21582
                     /locus_tag="TVR04_001231"
     CDS             20680..21582
                     /locus_tag="TVR04_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1269927.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCVFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(22483..22932)
                     /locus_tag="TVR04_001232"
                     /pseudo
     CDS             complement(22483..22932)
                     /locus_tag="TVR04_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(23495..23674)
                     /locus_tag="TVR04_001233"
     CDS             complement(23495..23674)
                     /locus_tag="TVR04_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutT"
                     /protein_id="HEL1269928.1"
                     /translation="MIQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAILGGDCVIIMTGA"
BASE COUNT         7190 a         5676 c         4276 g         6587 t
ORIGIN      
        1 aaccagagcc taaaccagag cctaaaccag agcctaaacc agagcctaaa ccagagccta
       61 aaccagagcc taaaccagag cctaaaccag agcctaaacc agagcctaaa cctgaaccta
      121 agcctgaacc aatgcctgat ccggcaccta aaccagagac aaaacctcaa aaaccaacca
      181 agccgtcaaa cgctactagc caatctagtg gcaaagcact accaaaaaca aatgacactg
      241 gcagcttgat gactgcactt ggtacaggct tactctctct tcttggacta ggcttcctgt
      301 caaaacgcaa aagaaagcaa taagctgaat aagctaatgc aagacagcac tagtatataa
      361 tgcgtgcatg gtccatctaa tgcagcacaa aagccttatc gcaccaaaaa tggggggtac
      421 gataaggctt tttgcatacg ctatagaagc tccaaaacca ctagactagg gcaacagcat
      481 ggcaaggctt acgcctctaa atcctgcaga gccttactaa tctgtgcctc taaggcttgt
      541 aaatcaccat tgttgtcaat cacgacatca gcatagactt ttttctgaga catggggagc
      601 tgacttgcta tccgctgctt agcagctaat tcggtcaatt gattgcgctc cataaggcgc
      661 ttgagctgtg tattgtcatc aacataaaga agccaaatag cgtcaaacca atcctgatag
      721 cccagctcaa ccaaaagcgg taaatccata aagaaaatat cctctgtttg agccagttgc
      781 tcctttttcg tggctaaggc ttctctaatg atagcattct gctgctggga ggacttagcc
      841 atgctgtctg catgagcaaa tagcagctct gccagcttag gtctgtctag ctctcctgac
      901 ggtagcaaaa tgtcctgacc aaaggtctca agcaagacct gataaagcct tcctcccttt
      961 gcttgcaact catgtaccac ctgatcggcg tcaatgacct gatagcctgc ttgcctgatc
     1021 aatgcaacag cagttgactt tccagaggca atgcctcctg taataccaat gatttttgac
     1081 attatcgttg acacctagga caaacatgtg tccctctccc tccaaccttt aatttcacaa
     1141 tagctgcacc acagcgctga cagggcttgc ctgtttggcc atagaccatc aagtagtgct
     1201 gcatactgcc attcattccc aaggtatttt gataggtcct aaccgtcgag cccccctttt
     1261 caatacctag ctgtaaaata cgaatgatct catcatggat ccgtttgatt tccgcttttt
     1321 ttagactagc agaccgacgc tcagggtgga ccttggccgc ccatagaacc tcatctacat
     1381 agatattgcc aaggccagcc accagagtct gatccaagag gtggggctta atggtctttt
     1441 tagaggctag cagagcagct tcaaagggct ttaagcgaaa ggcttgcttg gtaggctcag
     1501 gaccaagctg acgcttctga aaaaaggcag ccagctcaga ttttggcagc agctcaaagg
     1561 tcccaaactt tctgacatct tgataaacca aggtggagcc atcagtcatg gtcaaaaata
     1621 catgaaaatg cttctgatca ggcactgtat cagaaaacaa gaggtatttg ccctccatac
     1681 gtaagtgcga aatcataacc agctgaccaa ggtcaaagag caggtacttc ccacgacgat
     1741 ccaccccttg cacctgctgc ccagggatcg tcatcacaaa atgctcaagg tctgttttga
     1801 ccattttagg caccttaact gtcactgctg caatctgctt gccaacgact aagcgctcaa
     1861 gcccgcgtcg cactgtctca acctcaggga gttcaggcat aattaacgat accaaacgcg
     1921 ctaacaaaga aactacatga ccaaaaccag cagaatcagc cagtcttagc gtcttttgct
     1981 cagcctcaat gtcacaaaca cgcttccttt ctgtaaagct agtcttggaa aggcctgccc
     2041 aaaacctcaa taggcttgag cacaagggac tatcctttga taagaactat tatcattctt
     2101 attttacgca taatccataa agaaagcaac tctcacgaac aggccttgac ccatttctgt
     2161 tgaccaaccg tccttgctag ctagactaat acagtaggca ggctgagact ttaatctaaa
     2221 aagaagtacg ctgattgttc acccccatct gacaagccaa aaaatcccct gaaccagcta
     2281 attgtgagct gacccaaggg taaaaggaag tgtaagctta taagacagtg aaggacaagc
     2341 taccactaaa agccttggct aacttaggct tagcttagct gttcctttcg tcagattgaa
     2401 gacagtctag actgatcggc ttgtcaacaa gacggatact atcctggtaa acaccttctg
     2461 tttcaaaaat aacaatgtca tttaatccct tgttgaaata gccctttgga atataaaggg
     2521 ttaataaggg acccacttcc caaaaacgac caatagggtg attgttgata aagacacatc
     2581 ccttcccaaa gccagtcata tcaatatagc ttgcctcagg ctcatgacat tcaaattgat
     2641 aatgataaaa gccgggctgc ccctcgtaaa aatcgccatc aaaacaaagc tgagacaaat
     2701 catcaagcgg cagacaatac atctcccaat tggtcacaaa gtgcaagtca gccatcatac
     2761 cacgtcctag acccttactt tgactaggtg ctgtcagctt gtgcccataa ttgacccggc
     2821 ccatattttc aattaaaaca tcgacctgac tcaaggcatg ctgctggtta atgatgatat
     2881 catcaccaat cgtctcctga tactgtgttg caaccttttg accatctaaa aagacctgtg
     2941 ctctatctct actatcaatc aagcgtaaac gctcgtcctc acgcttatcc ttcaaaagat
     3001 gtgtccgata caggatatag cccgttgatt gccctaaagc ctctatgtta ctaggatagc
     3061 aagcagtctg acagctgctg atgtgctcca gcgtgctaaa cagactaacc ttgtccttca
     3121 gaccaatcag aggcagtgac atcaatggct taagcaaagg aagtgtcgac tctagctccg
     3181 gaaattgtgc tgtcaagcgc ttttggatcg cgtaaaactt agctgtcgga ttgccagcct
     3241 catctaagat ggcatcataa tcataagagg ttacctgcgg cagatctagc tgctttctgg
     3301 cagagcagcc attcataaag ccaaagtttg ttccaccatg aaacatgtaa aggttgatgc
     3361 tgccttgagc caagacctcc ataacagcat cagctagctc ctcagggtca cgtttgatga
     3421 taggttcgtg ccaacgattg aaccagccgt cccaaaattc catacacatt aaaggccaat
     3481 gcttgccatg ctcagaaaag aaggcctgca tgtcagcaaa attctcctgt gcccttgagc
     3541 caaagttgcc agtcacaaag acatcatctt caatcagact accagctcta agagtggctc
     3601 gccaaggacc atctgctgta aacaaaggcg cactgaggtg ctcctccatc aatgccttaa
     3661 tggcttttag ataagccttg tcctctccat aggagccata ctcgttttca agctgaaaca
     3721 tcaaaatatt gccgccctgc tgccattcat gccttgctag cctcggcagc agctcctcat
     3781 aatagcgcct cacgtaggct aagtaggcag gatcagacga cctgatatga caattctttg
     3841 tcagcagcca agcaggcaag ccgccaaatt cccattctgc acaaatataa ggactaggtc
     3901 tgacaatagc atagagcccc aattgctgcg ccagcgtcaa aaaggcttcc acatctaatt
     3961 ggccagagaa atcatagctt tcctccctag cctcatgtaa attccaaggg atataggttt
     4021 caaccgtatt aaatcccagt gcctttaaat tataaagaga gtgataccaa tcatctgggt
     4081 gaattctaaa ataatggatc gcccctgaca ggatttgcag cggtctacca tctaaataaa
     4141 attgatcaga aatctgaaaa ggttccaagt tcatttcctc acttactatt attagttgcc
     4201 cactaagtct cattgttgag cctatgtcag ctgattgatg ttaagctcaa taggcttata
     4261 gcaataacga taccgtctct cctctgctat taggctgtag taggatcagg ataagagaca
     4321 gtgtatgcct tgtcatctgt caatctaatg ccgtatttgg tttcaacaat agtatggtca
     4381 aactgtggta aaacagttat cggttcttca ggcatactat ctagagacaa ttcaaatatc
     4441 gctgtgtctg tgccatttcc taaaacatag ctggcagttt tttcaacacc atctacagta
     4501 actgctaatt gacgatcacc cagaataaac atcggttgat tgaaggtaac ctgaatcgtt
     4561 agtgttgctg tgtcattctg ctttggagct actgacgtta ttgttacttt ttcaatttca
     4621 gctttatcct cacgaaactg gtctgaaatc atctgcttga tattaaaggt tgaataggtg
     4681 atctgaccac tgtattcgta taacaaacca accctctcgt cgtctagttg aaccaagcta
     4741 gagtaagcaa agcgctttgg ctcaaaaatg gttgaagcga cccaattaat actgtcgtcc
     4801 tctaacacct cgccgacacg taaaatccct ttcatgcgtt gatttctaat cgtcaactgc
     4861 tcacctgaag gctctcctaa aggattggat aagacaacat attccttgcc atcaaccatc
     4921 atatgaatag ctgacaaatt gacataaggc tctggcaggt ctgtgattgt aggattatcg
     4981 ccccaggttg caccgtaatc tgtgcttctg gcaataacga ttgtctttcc ggtattgcgc
     5041 ataaactgta ataagtgacc attgtttagc tgaatgattt gattttctgt caattctgtg
     5101 actgatgtat caaaatcctt agaggttgtt tgttggttat gaccataaat tctgccatca
     5161 tttggtgatt cacctcgttg ccatgtttga ccgccatcat cactaaaaat attagcacta
     5221 ctttgacgac ctagactagc tgatgtcgca ttttgttgat tggtatagta aatcgggaaa
     5281 actaaccgtt tcacctgctc accctctgca ttgactgcgt ctatttcaat gccagctgcg
     5341 gcacccgtac ctaaaaatcc catccaatct tcttttattt gtggggtaat atcaagaggt
     5401 gtggaccagg tttgcccttc gtcttcactg gttagcagcc ataaaaagct ggtcatgtaa
     5461 gtaaatagag gagctgtttg tgagccttct ctagtgattc cttgcttagt gcgaccactt
     5521 ctcagataaa tattccccag tagaatatcc tctcctgcct ctgttcgata gaggttgccg
     5581 cgcgtgctaa aggctgtctc aaaattgccc tcatcaacat acatatctgt ctgatgacca
     5641 ttctggtcat agacgatacc accttcacgc acagtgtatt tattattgtc aaaatcataa
     5701 agatttaaat aatactgacc gttaatcaat tcatatcctg agcctgcttt agaagcaaca
     5761 gcaccctgtg actcaggaaa gacatctacc agcaaataaa gcttgccaga agcgtctgtt
     5821 agcaaggtgg agtctattga aaaagcagat tgagtcatgt tggtattcca atcagccaag
     5881 ctatattgtg ttgtaaaata aggctgagtt ggcatatcta agaccgtaat gttattactc
     5941 caggttttgc catcatcatg gcttatcctg acaacagttg caatgtctcc ccagtcattg
     6001 tagtgcttct ttcttgcatc tgctgcagct actaaggtgc ctgatggggt tttaacaacg
     6061 gagggaatac ggtactcaaa gaccccttca tcatacttat cccaaacgtt cgtcttttcg
     6121 ccagtaactg gtcgaagggt tggctgatga gccttggcaa tatctgtcag atcatagaca
     6181 tctgtatcaa tcagcacctg atcaaccagt ccctttaacc cccaatggaa ggctgattcg
     6241 ccatcataag atcggcttaa tcctccaacc gttactgtat cagcagaagc cttccaaggc
     6301 aattgcttca taaacccagc aaagtcagct tctccatata agtcaccatt caagtaaatc
     6361 tttagcctag accctgtaaa gacatagctg atcgtctgcc agtctgagtt agttagtagg
     6421 ttaaagcctg agcccacttt tacaatcggc acctcagctc ctttaaactc aagacctatt
     6481 ttattatttt taggctcgat aaagaaagag gcgtattcat tggctgatgc ttgatttgag
     6541 atcgataaca gggctaaagg tgatgcactc cttacggttg tatcagcagt atctaggcgg
     6601 tacctgattg ttactgttcc ttgatttaag ctcatcacat catctagctt gctaagaacc
     6661 tcgtcatctg ttacggctgc tttttctgcc gttgcgtcca aaatagcatt gcctaaatca
     6721 actaaaatag attgttcatc agagcttggc tgatctgcga tatagcttgc ctctatcgtt
     6781 gtataaacag ctcttccacc ttctgtggtg tatttgacct gatagcgatc agcgcttcct
     6841 aagagctcct ctggctcaac ccattgccaa ttggttggta gggcaactgt agacaagggc
     6901 tctccttttt gaccatataa cccttccttt ggcaagactg ttagaatagc cacttctctt
     6961 gcaatttttg ctgttggggt cactgttgat cctagattag cagcctcagg aactgcacta
     7021 tagtaaatat tataaatacc aggagctaat tcagataaag ctgctaagtc atttcgtcca
     7081 gaagcctgca aggtggcatt ggtattccca cctttgttgg taaacaggta ctcattttca
     7141 attgaaaaat caaccacata gccttcctga tcagtggtta cagcttgagc taaatcagga
     7201 ctggttccct ctagcatggt caaatccttg acccccttga gaactggctg tgaggcataa
     7261 taagcttctg aggctgcttt ttgctcagcg tcttggtaat aacgcacata atcaatcaca
     7321 aaggctgtct catctgaagc tagatagtac cctgcatttt tgctccagtt tcctccagtc
     7381 gcaaggttga attggagata ttgtggcttg ttaaaagcag ctgctgccgc ctctaagcgt
     7441 tcatcacctg ttaaatacat ggtgttgtaa acaatcccat caacatacca ctcaatctta
     7501 tctggatacc agttaatgcc aaaaatatga taatcatcat aaaagtcatc acttaatgtc
     7561 agattgccac ccaatgcagt tggactatag ctgccgtcct tatctgcatc acctttgacg
     7621 tagtaaaaat gaggggtccc gtaaactgtt ttgttgcttt gatcaccttc ggcaagctca
     7681 ccctcatgct ctccgttagg agcaccgatt agctccataa tgtcaagctc acctgtgctt
     7741 ggccagccat agccttgagt tgacgcaata tcaccatcta aggtaaaatc agcccccaat
     7801 gtccaaaagg ctggaaaggc tcccttaccc ttgggaagct tggccctagc ttcgatacga
     7861 ccatataaaa attcttgctt gccaaccgtt cgtacgcttc ctgaatcata aatgacctga
     7921 cgtgcgcttg ttcctcctct aggattggca taacggtcct cacccttacg ctctgtgacg
     7981 tttaaaacaa gattaccatt ttcaagataa acattctctg tgctgtctgt gtagtgctgc
     8041 tgttcattcc cgcgaatact tcccaattca tatccccagt tctcttggtt taaccgatct
     8101 cctgaaaact catcctccca aatcaattca taatcatttt cctctacgac actcacgtta
     8161 tcaatactag cagaggcagc caaggcttcc ggagaagagg cttccaacca tttgactaag
     8221 ccaacaaagg tttctgaagt cgtcgctgta aaggagaatt taatatgtga ccaagtaccg
     8281 tctgtatctg tgaggctgac ctctttgata acaggacctt gaagattgtg gttggactct
     8341 ttagcggtaa ggtataagcc attatgaggc gtagcagctt caaccttcac atcagcctct
     8401 agcgtatagg ttttcccaac cgttgtagac accttttgaa ggatatgctc atctaaagtg
     8461 ccgcttgtta cctcagcata gctattacca ttttctgttg taagaactga atgacctccc
     8521 tctctatatt gccactgcgt cttattagag acatattgat gatcaaagct accgtcagtc
     8581 accttattta agtccacagg agctttttga tctgcttgat caggtgcttg gttaacagca
     8641 ggatcattgc ttgctaccat gtcaatcact actacttcac ttgcctttac tgcttctgaa
     8701 acgtctaagc tttcactggt ttctagatga agctcttggt cattgcttgt atctgtcaca
     8761 actgcctcaa taggcggctg cgggcttgcc tctgacatat cctcggcaaa aacagctacc
     8821 ggcagacaga cagcaagacc aatgccgaca catactgaag taacaccaac actaagcttt
     8881 ttgatagcat atcttctgac ttgctcttga ccactacgat taaaaaacat gttcatttcc
     8941 tcacttactt acctgtataa caccaacaaa aggtctactc aactggtcct ttcccttgct
     9001 ggcagtgcta gactatgcac atagcctagt tataaaaacg ctttcaacaa tacacttaaa
     9061 agaagatata ccagatgaca ccgatatatc ctctcacaga gtgactaacc tgccttttca
     9121 agctcattat cagccatttt aacaaatgga aggtaaatca aggttgctaa agccaaattg
     9181 acaagggata acacaatagc acgccaatca aagccagttg aaaagaaacc atacaagaca
     9241 ggcggcatta cccaggtcac attttgcgta acgggtgcaa ccaagcccag actagttgcg
     9301 atataagcaa cacttgacat aacagcagga caaacaataa acggaataaa caacaaagga
     9361 tttaaaacag ttggtaaacc atacatcact ggctctccta tattaaacaa gacaggagca
     9421 acacctagct tagccacctc acgatagtgt tcatttttag acttccagaa aatagcaatc
     9481 aatagcccta aggtcgcata ccatacaaag gcaccataag aaacactcgt ccaaagataa
     9541 ggaatcgctt catgcttttg ataagcctcc aaattggcca agagggcaac accaaacact
     9601 ccctccataa ttggcgccat aacattgccg ccatgaatcc caaagaacca gaaaaattgg
     9661 gtcaaaacag ctaccaaaac aacagcaata aagctttgtg ataagcccaa aagtgggatt
     9721 tgcaagacct tataaatcca atcaatcatc aaagaacccg ttagcttttc aaagacaaat
     9781 gttaaaatag ctacgctata caaggcgcaa aagcctggta tgatagataa gaagggcttg
     9841 gctacagcag gtggcacact atctggcaat ttaattgtcc aattttttaa cattaattta
     9901 caaaaaataa tagaggctaa aaagccaata ataattgctg taaaataacc attggagtta
     9961 atttgcgcac caggcaatag gcctgagatg gtcacattaa gtgagctgcc gctgacagta
    10021 acaccactgt ccttaaaagc cgtcacaaga tcaacaccct tgagacctga cgcgtcaatg
    10081 ctagaggtaa cagaatcccc aatcgcaatc acaaaggcag ctaaagaaac caaacctgat
    10141 gagagcgtat ctgtcttata aagtttagcg acattaaccc ctaagcaata cacaaatagc
    10201 aaggacacaa tcgaaatgct tcccttaaag acaaggttgt tgatggttac ccaccattgg
    10261 aaggcctctg taatgccttg caagccaaat tggtctggaa tatccactaa aaaggcattg
    10321 atcaacaggg caatagagcc tgtcatcaca accggcatcg ttgcaataaa ggaatctcgc
    10381 aaggccacta aaaatcgttg attaccaatc ttcgtagcaa ttggtagcag cttttgcgaa
    10441 agaaagttca tatagttatt cattcatagc tccttaaaac aatcataaaa cagctaagat
    10501 agagcagtaa aggctctctc taacagctta gccttcattt gtagtttgct cgcttgcctg
    10561 ccatcttctt tccacattaa taataaatgg caagtaaaga agaatatcta gaataattaa
    10621 aacaagctgt aggactgagg cttgccagct gcctgttgcc aaaaatcctg aaataacagg
    10681 cggcattgtc caacccagat caacataggt accaggtaca ataccagaag caaaggcaaa
    10741 ataagcgaca aacaaattca taacaggtgc taacacaaaa ggaataacgg tcaatagatt
    10801 taaaacaacc ggtaagccaa acatggtcgg ctcgttaatg ttgaaaaatc ctggaatcaa
    10861 ggtcaatggc gacaaaacct ttgcctgctg actagccttg cgacgacgtg ctaaccaagc
    10921 caaagccagc accaagccaa tggttgcacc agctccaccg ataaaaacaa agttatccat
    10981 aaatacagac gtaaagacat gaggtaattc ctgaccagcc ttatgagctg ccatattttc
    11041 agtcaggtta gacaaccaga tcggcttcat aataggattg tttaggacat ttccaccatg
    11101 cacaccacag aaccataaaa agccattaag aagaacaacg ataaaattac caaataaggt
    11161 acttcccagc aagccaaatg gaactcctag tacggactta acaatgtcat gaacatttgg
    11221 caggctaaaa tgatccaaga aagcataaac agcaagccaa aacacaataa tcaccgctcc
    11281 aggaataatg gcgctaaagc tttttgatac tgcaggcggc acaccctcag gcatcttaat
    11341 ccgaatatcc tttttcataa accattgata agcatagccg tttaccaatc ctaaaacaat
    11401 ggcaacaaac aagccgcctg atgaaaggta agaaggcgca atacccgcta cctcacccaa
    11461 ggctttacca gattcatcga caaatggaac agtaaacggt gtcactgtta aaaaggcaga
    11521 gatattaata atcccagcag aaatcccgtc tgccttatac tgcttagcca agctataaga
    11581 aatcccaaag gccgcaacca aggcaatcag attaaagctc gaatctactc ccttccacag
    11641 ataggtagag acaccaatct caccaagcca aacttcccaa ccaggaatcg gcaggctagc
    11701 aatcaccatt aaaaaggacc caatcaaaat caagggcata gcgtaggtga tcccatcacg
    11761 aatagcaata agaaagcgat tgcttcctaa gcgaccagca actggaacaa gcttttgctg
    11821 gataaaatct tcaaatttag tcattgttac ctccttgtga cgttaacctt tcataaatag
    11881 atactagctc ccttgccaaa tcaacaaagg taatactagt catcaaatga tcctgaccat
    11941 gaactaatag taggcttact ggcgtagcat ttcctcgtgc ctcttgagtt agcatatctg
    12001 tttgtgcatg atgggcctgc accaacgcct catcggcctg ctttagactt tcctgagctt
    12061 gattgagctc tcccttttta gcaaaagcaa tcgcctccat cgcaagcgac ttggcactac
    12121 caccatgcat gatcaggccc ataatcgttt ctagctgctt atcttccatg accaccacct
    12181 atttcatcaa gctttcagct aaggcaataa ccttatcacc attcatcata ccgtaatcaa
    12241 ccattggcac aaccgcaact ggaatgtcct tttctgccaa gctttcctga aatgctgaca
    12301 attgataagc aacctgtggc cctaataaca ccacatcaac aggatggctt agagcataat
    12361 cccctgcctc agtcaatggc aatgcaaaaa tatctgcttg cagtcctcga ttgtcagccg
    12421 ccttttccat ctttgtcact aaaagactcg tgctcatacc tgctgcacag gccaacataa
    12481 tttgtttttt actcatgatc ttctccttta tcccaaatcc taacgtcgaa tagagcgcga
    12541 cattctcaca atggtgtgtc tttttcctcg gatagcgtca ctaagggcaa agatattttc
    12601 caccggcgca attccgctat agccagcatc accaatatga tgaatgtcga caccacagat
    12661 tttattgcga atagcaatat ctcgaacgat cgtagtatct gacccttcct gactcgttcc
    12721 aatagctgac atgatcaggg catcgtgagc atgcacctcc tcgacaatag ctctaaggtc
    12781 accctctgta aagccaggaa ctgtcccaac agcaggaact aaaatcacat cagctccagc
    12841 ctctataaat cgccgaacag tttctaagtc aatcaccgct tcattagagc cagcagcatg
    12901 catcttccca gcaataatca agcctgaaaa atagtccttg gcctgttgaa tagctctttc
    12961 aatttgatta ttgctaacac cagtgcctgg atttcctgtc aagcaaacaa agtcaaagcc
    13021 caaggcttca atctcttgaa aggtcttagc tgtcgcctgt cgcccttcta ctagctccaa
    13081 gcgcttttca gtcatgtcaa catctaaatc aattggttct aaattaacac ctattggacg
    13141 ccccaccaga cgacgcagct ctaaaatagg ctgatcagta gcaggtagac cagatatttg
    13201 aacatcaaag acatctacac agttcagcaa gatcaaatca gcactaaaag ctgccgcaac
    13261 ctcagcgttc gtaaggtcat ctcctgtcca agagggtctt ggcgctacat tttctgagac
    13321 aatggtacgt ccctcgcttg ccttaatggc ttgctttagc tctaacgatg ttaactgtag
    13381 catttctgag ctactagcac tcaataatcg tgttttcatc gcttctcctt tatttttatt
    13441 ttaaaaacat taacaaaaga taaataagat ttaactctta tttgtttact ttttataaac
    13501 aaataaagta tattctattt accagtattt gtcaacgttt tcaagaagga tttttaattc
    13561 ttttttggta tgatagaggt acaacaatcg aggttactat gaagacggat aaacaacaag
    13621 agctttacgc aaaaatttta gataccattt atgcccaacg gcctatttcg cgcattgata
    13681 tttcaaagct aacgcatatc acacctgcta cagtaggggc tatcactaaa gagctgctag
    13741 cacaggggtg gatacacgaa atcggagagc tgacggacca ctccgttggc cgcaaaaaaa
    13801 tattacttga tgcttcggct aatgcctttt attttgctgg tgtcgaatta tccgaaaagc
    13861 atttctattt ggtcattaca gataacctgg gtaccatcta tgccaagcac aaccagcagg
    13921 tcgacccaag catttcctcc tactacaagg cagactatat ctctgagctg atccaagtct
    13981 ttctcaagca gcacaagcat tatagcgtac aagccatagg aatagccctg cctgggcatt
    14041 acgatcactc catctctagc tcaacacata ttaataccaa caatcccatc tggcagcagg
    14101 tcgatttgac tgcaattgcg aagtccttct ctattccagt ggtctttagc aacaatgctc
    14161 attgtatgat tattgctaag cgtttatacg agcaacaggc acataatcac aattttattt
    14221 tcttccatgt aggacgaggc atgcactgct cttatatgta taagggggtc atttatagcc
    14281 gtcacaatgc agtagttggt gaaatcggac ataccattgt caaccccgct ggagagcttt
    14341 gtgaatgcgg caaaaaaggc tgtttacaga cctatgccag caatgcttgg ctgctcaaaa
    14401 aagcaaagct gctgcatcag tacgctcctc attctcatct aagaagtctt gttgataagg
    14461 cctgtgagct taagctagac catctcttga ttgcttatga gcttggcgat gtcggagtga
    14521 ccacgctcat tcacacagct attgattacc ttgttttatc cctgtctaac ctctccttac
    14581 tgattgatac cgagcaaatc tatctccatg gcagatttat cagccatcct cttatatcct
    14641 ccaaaattct gcaagccctg caaaatgaca ttaagcttct tagcaatcaa aaaaagccag
    14701 aaatcattgt catgcctttt tctgtctata atgccgctgt gggagctaca ggcttatgta
    14761 tagatgaact ttacctcaat tataaaaaca aatatgattg ataaccccca caccaatatc
    14821 agctaaagct ttaaagccca tttgagaagc tatttctcaa gtgggctttt gcattatgcg
    14881 actttcagtc catctagctc cgcaggtgcg agacaaatga taaccataaa aaaagagagg
    14941 cacttggttc tctctgttct atcctaatgc cccatttgaa actcaccagc aaaatactct
    15001 gccagcatca gtctatgctt gtctgagatt gaagacagct ctgcaatctc ttctctagaa
    15061 aaataaccga gccttaaggt ttcagcattt tgataatcag tgatagcctt atctgccttg
    15121 gctataacct cataaagcat cacaacggtc tgaaccttat caccatttgg ataggtctct
    15181 tcaaaattgg tataaacatt caacaaccgt aaaggctcta ctgtaatccc cgtctcctca
    15241 taaaattcac gcctgcaggt ttcagcagaa gactcaccca gctccatggc acctcccgga
    15301 attgcccagg ttttcttatc tgcacgtagc tgcaaaagca ccttaccttc ggcattggcc
    15361 aaaataccac cagcaaaagt cagaataatg ttatcatgcc ccacctttga gcgaatatag
    15421 gaaatatagt cctgtgtcat cgtaactccc ttcattgcca tcataagatt aaagccagtc
    15481 agctggcgca attgctgctt ttttgccaac caataagcaa tgcaggcttt gtctcttgtc
    15541 cttgataggc tggcaaagca tatagcccta atttttcaac ctgattatat cacacttttt
    15601 aaaagccaga aagaaactta aataccaagg ccatgccaaa cgcgcgaaac aattctttcc
    15661 gaatgatagt atagagtaaa gcagacagct tcaatggttt tcctatctat aaactaatag
    15721 atcaatggtt tgccattgat ctactgtgta ttaaaaaaac agactagtta aaataatgat
    15781 gctctcggct accaaagtac taccaaaaac tgtaataaag gtttgtttaa agccattttt
    15841 atgattgaga ccagtaaggc tcaagaaggt taaaaagacg ccagactggg gtacaatggt
    15901 caaaatatta gaggcaacag ctgccacacg atgaatgatc tcaggtgaaa cgcctgcatc
    15961 taaataatat tgagcgaagt ttggcattac gatccctaac gctcctgaag acgaacctgt
    16021 aatagctgcc atagccgaag tcaggacagt caagctgatc acaggtggcc caggaatatt
    16081 caaaatgatg tctgagaata cgccaaaacc agatgctgcc gtaacaacag agccaaaggc
    16141 tactgcagag gctgtcgcaa agattggacc aaccgcaccg ctagcaccaa tgctgagggt
    16201 cgcaattttc tgatcaatgt acttgttaaa taaaacgata gctgaaataa ttcctgtcaa
    16261 gagggccaca taaatgatat ttttcttaac gaattcgtcc cctagcagac tacctatgat
    16321 ggcaataaca atcaagagta tcaaaggcaa gatgctggct acaaatggtg gtaaaaccct
    16381 ttcagttgta tcttcatttg tttgactagt ataggtcgca tagttttcac caacttctaa
    16441 actcttagtc aaacaacgct tcatatagaa aagaccaaag gcgatacagc caacgctacc
    16501 caaaatactt ggcaccaggg ctgcggttag agacgtgttg aggtattgta tagggataac
    16561 attttgaatc gctggtgtac caggtaagat cgtcatagta aaggttgcaa tccccaacca
    16621 aagtggtact tgaattaaat tccatgataa gtccatcttt ttaaagagag agcgtgccaa
    16681 ggggagaaca gcaaacatga ccacaaagag actaatacca ccataagtca agatagcact
    16741 gatgataaaa atagccacca agatacggta ggggttttga taacctactt ttttcaagat
    16801 aaactcagca atggaaactg ttgcaccgct gacttccatc aatttagcta aaatagaccc
    16861 caacaagaag atagcaaagt agctcatgat atagccaccc agcgcgccca tatagttatt
    16921 tggttcctta cccaagagtg actcaactag tggcatacta tttagaagga cgaccaaaat
    16981 cgttgccata ggagccgcaa tggtaatatg aatttccttt agagaaaaat aaacgatggc
    17041 aataatgccc agcaagaccc caattggtcc taaaaattcc atagtatttc tcctctcaca
    17101 ttcaaaagga gcaagagata gagcaatgtc actctatctc tgatcctcct attttgcact
    17161 gaacggatag ctcttattga gcagtgtagc caccatccaa gataaccggt tgaccagtaa
    17221 ttccctttgc cttatcactt gccaggaagg agacataatc tgcaatttct tgtacgtcaa
    17281 tcaaacgttt ttgcggtacc aacgggtaca acacttcttc caatacattt tcaagcggaa
    17341 tcttacgtgt cttagagagg tcttcaaatt ggccacgaac gagtggtgtg tccacatagc
    17401 ctggacagat agcgttgact gtgataccta aatctgcggc ttcaagcgct gcaacctttg
    17461 tcaagccaat caaaccgtgt tttgctgaat tgtaagccgc ttttccggca aaaccaatga
    17521 caccattgat agaagccata ttaatgacac gaccaaagcc ttgctttttc atagttggaa
    17581 aagcgcgctt aatagcaata aatggcgctg tcaacatgac cttcaacata aattcatatt
    17641 ttgctgttgg aaaatcctca atcatagcaa catgttgcaa acctgcgttg ttgaccaaaa
    17701 tatccaaacg accatgcttt tcaactgtat agtcaattgc tttgttgatc gcttcttcat
    17761 ctgtcacatc acacaaaaca caatccgctg cccatccttt tgttgtatac tcatcaacaa
    17821 cagcatctaa tttttcttgg ttgatatctg agaagacaac aattttgccc tctttcaaga
    17881 atgtttcacc aatttgctta ccaataccgc ttgctgcccc tgttacaaat actacttgtt
    17941 tagacatatt tatttcctca cttttttaaa acatatttcc tattagttag gacaaatcaa
    18001 tcttgcttca gttacttctt gaacttcttc aaaggtataa tctggatgaa tctcttctac
    18061 cgcgattccc tctggagtga ctatgaagac acccatctct gtgacaatct tgtcaacaac
    18121 tcctgctgct gtcaatggca atgaacactc cttcaagatt ttccatttgc ctttattggt
    18181 atgctccata gcaacaatga cttttttagc accgactagt aaatccatgg caccgcccat
    18241 tcctggaacc attttccctg gaataagata gtttgcgatg tttccttttt catcaatttg
    18301 caaagcgcca agaactgttg catcgacgtg gccaccacga atgatcccaa atgaagtggt
    18361 gctatcaaaa aatgctccgc ctggtacgat gccaaccggc tgaccacctg cattaactat
    18421 agttggatca atgtcatcgc ctactttatc taagccgaca aaaccattct cagattgcag
    18481 catgatggtc acaccttctg gtaaaaatct agctaccttg gttggcaagc caatccccaa
    18541 attgaccagg gaattatttg gaagctcgag tgccacacgt ttagcaattc gttcttgaat
    18601 ttcttctttg cttaattctt tcaccataac actcactctc cttccactag ataattgaca
    18661 aatatgcctg gtgtttgaac tgcaatgggt tcaattgctc caaccggtac aatgtcacgc
    18721 gcttcaacga tggtaatttc tgcatttgct gccatcactt ggttgaaatt attttcagaa
    18781 cccttgtagc ataagtttcc taattcatca gccttatctg caaaaattaa agcgacgtca
    18841 gctttcaatg gtaattctaa aagataatcc ttgtcattga cctgtaattt ttgcttgcct
    18901 tcttctacca aagtaccgat acctgtcgga gtcaagaagc cacccaatcc gtaagctcct
    18961 gctcggattc tttcagccaa ggttccttgt ggcactaagt caatgactgt ttcaccagct
    19021 gtcatttggc gtcctgcttc tttgttcaag ccgatatgag aagcaatgat tttctggaat
    19081 tgatgttgtg ccaccatttt accgacaccc ttgtctggaa aacctgcatc gttacaaata
    19141 agggttaaat gtttaactcc ttttgctacc aaagcatcaa tcaggcgctc tggactcccg
    19201 ttggtcataa aaccaccaac catgatggta tcgccatcct ttataaggtt cacagcttct
    19261 tccatgctaa ttcgtttatt catgaaacga tctcctttta tttttcaatc aatacagatg
    19321 tcccttgacc gccaccgata cagagtgttg ccaatccttt gtgcgcctga cgcttttcca
    19381 tctcgtgcaa tagtgttacc aagatacgcg caccactagc accgatcgga tgaccaagag
    19441 caatagcacc gccattgaca ttaacgatat ctgcattaag accaagctca tctacaacac
    19501 tgatagcttg tgaggcaaag gcttcattgg cttccaccaa atccaagtct tcaattgtcc
    19561 aaccaacctt agcaagagcc ttctgagtgg aaggaattgg cccagtaccc atgacctctg
    19621 gtgctacacc agcacttgcg taacctttaa taactcccat aattggaaga ccaagctctt
    19681 cagctttgtc acgactcatg agaaggacag ctgctgcacc gtcattaatt cctgaagcgt
    19741 ttcctgcagt aacagttcct gagccatctc ggacaaaggc cggacgaagg gctgttaatt
    19801 tttcaagggt tgtcccagct ttaatgtact catcctctgc caccaagatt ggatcacctt
    19861 tacgttgcgg tactggaact gaaacaatct cgtctacaaa gcgaccagca gcttgtgcag
    19921 cagcagcttt ttcctgactg gccaaagcaa atgtatcttg agccttgcgg ctaatcccat
    19981 agttttttgc gatattttct gctgtaattc ccatgtggta atcatgaaag gcatctgtca
    20041 aaccatcatt gaccatagta tcaatgattt ttccatcgcc taagcgacca ccccaacggt
    20101 aatctttgag cacatagctg gcttggctca tattttctgt cccacctgca ataatgatct
    20161 ctgaatcacc acagacgata ctttgtgctg ctaactcgat ggatttgaga ccagaaccac
    20221 agaccatatc cacagtgaag gcaggtttgt cgtttggaat acctgcagtt atcgctacct
    20281 gtctagcaac attttgacca agtcctgcat ggaggacatt tccgaaaatg acctcgtcaa
    20341 tttgttcagg cttcaaacct gatttctcta gtaatgcttc tacaaccact tttcctaatt
    20401 gaacagccga gacagtttta aaggctccac caaatgaacc aatgggtgtc ctaacagctg
    20461 tagtgataac aacttcttta accaacatgc gattctccaa tctatttgtt atagaaagcg
    20521 ctttctattt ttgtaaattt attttatcac tactaaaagc gtttgcaaaa ttcgattttt
    20581 ttatatgact ataaaaattt tttattattt tttattgaca gctataaaaa ttattattag
    20641 tatgaagaaa aagacatctg aaatgaaaga agaggcaata tggatattaa acatttacgc
    20701 tttttcattg ctattgtaga aaataatttt aacctgagcc gtaccgctca acagctttat
    20761 atttcccagc ctaccctcag tattatgatt aatgattttg aagaaaagca gggcattaag
    20821 ctcttcaata aaaaatacaa taaaatcctc ggcttaacca tgacaggcaa gcaattttat
    20881 gaggattctt tggaggttat ccgcaaatat gacaagatgc accaaaatct cttttccacc
    20941 aatcaaaagt tggacggtaa tatcactatc ggcattcctc cattaattct gtcaattgtt
    21001 ttttcaaaaa tcatgccaga aattattcta gaaaatccca atatccactt taatattaag
    21061 gagtatggtg ctaatcggct acgtcaggaa ttgattttag agaatgtgga tatcgccatt
    21121 cttctgcatc ctgaacgaat tgctgcaaac accattgatt ctttccaaat ccaagaatct
    21181 gagctctgtg tatttgtttc caagaaccac catttggcca ataaaaaaat cctgacttgg
    21241 atagaactcc acaatgaaaa actagctata tttgataaaa ccttcatgat tcaccatctc
    21301 atcaaggaaa aatgtaagta tactgacatt aacccccaaa tcattctgga atcagcttct
    21361 tgggactttc tgatcaattc tactcgtatc aaccctcaac taatgacgat tattccaaaa
    21421 ccaacggtag atagctatgg ttttcaggat attgtggcta ttcctatgga gaatcctatt
    21481 ccttggaaag tcatggttag tcgtctcaaa aaagatcatt attccaccat agaagaatac
    21541 attttcaaca aaatgcttga aaaatttcat gtaatcgaat agagactaac aagtgatccc
    21601 tttcacatga ctgcacgtgc ccttcgacat atggcacctc aactaaccct tagcgcatat
    21661 ggaaacagct caattctttt tgaaggataa aactaaagag gcttgaagat ccatactaac
    21721 tcagaccaaa tattgctatc aagagcctaa atcttaaaac aactcattta aaacaattaa
    21781 ctaaccaaaa aatggtctac tcctttgagg cgtgacagca atactgcaat ttgtaaaaaa
    21841 tgactgtcag gataatatct ctgaactcag tcacacactc tctcaaaagt caattcacat
    21901 ctaatggagg actatcaaga aaaagttatt tttaaaatca tcaataacct atctaaatct
    21961 tctaaacgat gtcatataaa aagagctgga gtcaccaagc tctaattgat ttttacatga
    22021 tgctctataa caatatcgtt taaagatcat tcttttttac tagtatgttg atcacatttt
    22081 ctaaaagcca gaaagagact tgaataccga gtcccttttc tttttatcta tagacagccg
    22141 caaagaagcc caaacaagct aggataactc tcttaacatt agcttctgcc acttctcttg
    22201 ttaagccctg ctcacttgat gattcgttat ttttaccacc tgaagactct cctttacata
    22261 agctgctttg tcatctagtt cctgcctatt aacgatatat catcgtctca attgatacca
    22321 ttttccttat catcttggga aaaagctaat ttctatacct ttaggtgttc tagatcacaa
    22381 aatagctttc tcaatcctat ctaccttgca agaattcatt gaatgccctt aacttttgca
    22441 gtaacgacaa taaaaatagt ttagataacg atgctattga tgttactgac ttaccctctt
    22501 cattgataag tatgctaaat ataagcaaag aaatgcaaaa gctaatctaa tcatgacaat
    22561 aactaatcca tcaacccaaa aactgccaaa aaagccgtca taagcaagct taagcattat
    22621 gtttggtgta ctcgcagttg atacagataa aatactcaac accttatgag gtattcctgc
    22681 ttggaaaata tccataagaa agcttggtac aaaaacacta gccgcagaca aggcaaaacc
    22741 tgtcaatgga gacttaacct tacttgaaat aaggatagtg atagccgtaa tcaggataag
    22801 cccaataaac tgatagatga ctagattgat aaatgttccc aaaagggtca gtttttctgg
    22861 aaaagccatt atattcacat tattgttaat ccaatacaga ttgagttgaa cactcgtgtc
    22921 ccaaccactt aaacgacatt cgtatgagac attttcatgc ctctgttatt cttatcagaa
    22981 gccatattaa ttacgacgac attttcagaa atcattatcg tgtgtttggt atcatcgaca
    23041 caaccgctaa taaatcgttt aaatgtattc aaaaccaaat tcatgattac ctgttcaaag
    23101 aataaccaga gggcttactg attgctttaa caatcttttc taactttctc attttacgcc
    23161 tatataaact aatctacttt gctaaagatt gctgcgaaca gaaaagcttt ctcaatctat
    23221 ttcagtttta tagccgtagt taggtttaaa gtacccccct gcattttcca tacctaagat
    23281 caattgactt gctttctcag catcaacagt catgttatcc ataagatgcg atgtattgtg
    23341 gttattgttc ttctagattc agccttacct cctgaaaata aaaaacgaga acacctttta
    23401 aatgttctca tataagcaat cttatatatt aaatgaggat ttttttcctt cataatagat
    23461 tatagaatac ttaaattcta gatttatcat cgttttaagc acctgtcatt attatgacac
    23521 aatccccacc cagaattgcc caggttttct tatctgcacg cagctgcaaa agcaccttac
    23581 cttcggcatt ggcaaggatc ccaccagcaa aggtcagaat aatgttatca tgccccacct
    23641 ttgagcgaat ataagaaatg tagtcctgta tcataaaatg tcccttttag gctttttctt
    23701 gtattttgaa ttacctagca ccactagta
//
LOCUS       DARYSY010000034        23660 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYSY010000034 DARYSY010000000
VERSION     DARYSY010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23660
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            98..970
                     /locus_tag="TVR04_001234"
     CDS             98..970
                     /locus_tag="TVR04_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1269929.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     gene            1050..2669
                     /locus_tag="TVR04_001235"
     CDS             1050..2669
                     /locus_tag="TVR04_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1269930.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTIDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            2792..5356
                     /locus_tag="TVR04_001236"
     CDS             2792..5356
                     /locus_tag="TVR04_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1269931.1"
                     /translation="MTKPKTWYLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYGSLSLLFIQHYYFGYMVAIFVFLLFLVNLISL
                     DTWKRRLRACLSFISVSILSALTSAFILIPAYLDLAAYGEKLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMVSF
                     YLQPLDLFWQGMHAPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIVFAFILLSC
                     LLTLPYLTMDQYSFLQPNLLILSLSFLAAYLILLLSMQKDSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDKLVKKAATNNDQFFRLEQLLPQTGND
                     SMKYNYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGVKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNVYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQAFNGRISGEAAENTSTTIVHYQVTVPDHRQLYLSLPNIS
                     FSNHNTTAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLR"
     gene            complement(5578..5651)
                     /locus_tag="TVR04_001237"
     tRNA            complement(5578..5651)
                     /locus_tag="TVR04_001237"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5615..5617),aa:Asn,seq:gtt)
     gene            complement(5684..5755)
                     /locus_tag="TVR04_001238"
     tRNA            complement(5684..5755)
                     /locus_tag="TVR04_001238"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5720..5722),aa:Glu,seq:ttc)
     gene            6036..6109
                     /locus_tag="TVR04_001239"
     tRNA            6036..6109
                     /locus_tag="TVR04_001239"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6070..6072,aa:Arg,seq:tct)
     gene            complement(6395..6874)
                     /gene="rlmH"
                     /locus_tag="TVR04_001240"
     CDS             complement(6395..6874)
                     /gene="rlmH"
                     /locus_tag="TVR04_001240"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1269932.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            7084..8307
                     /locus_tag="TVR04_001241"
     CDS             7084..8307
                     /locus_tag="TVR04_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1269933.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            8427..9200
                     /locus_tag="TVR04_001242"
     CDS             8427..9200
                     /locus_tag="TVR04_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1269934.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTSKEQELYFHNILDQGLSVRQIEQLVKTKHPQKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            9434..10786
                     /gene="dnaA"
                     /locus_tag="TVR04_001243"
     CDS             9434..10786
                     /gene="dnaA"
                     /locus_tag="TVR04_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1269935.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPTVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            10943..12079
                     /gene="dnaN"
                     /locus_tag="TVR04_001244"
     CDS             10943..12079
                     /gene="dnaN"
                     /locus_tag="TVR04_001244"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1269936.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKDFKAVATDSHRMSQRLITLDKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKDFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            12157..12354
                     /locus_tag="TVR04_001245"
     CDS             12157..12354
                     /locus_tag="TVR04_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1269937.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKRVLQP"
     gene            12478..12840
                     /locus_tag="TVR04_001246"
     CDS             12478..12840
                     /locus_tag="TVR04_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1269938.1"
                     /translation="MTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATPD
                     LENLVTLAAVLEVTLDELVTGKESAIKVTKKTEKPMNVWEFLTEESKRPISKGDLLML
                     LLVPIVLLGVYLIVIYFS"
     gene            12924..14039
                     /gene="ychF"
                     /locus_tag="TVR04_001247"
     CDS             12924..14039
                     /gene="ychF"
                     /locus_tag="TVR04_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1269939.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     ATPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKLEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            14198..14767
                     /locus_tag="TVR04_001248"
     CDS             14198..14767
                     /locus_tag="TVR04_001248"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1269940.1"
                     /translation="MVKMIVGLGNPGSKYQQTKHNVGFMAVDRIVNDLDISFTEDKTF
                     KALVGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            14770..18264
                     /gene="mfd"
                     /locus_tag="TVR04_001249"
     CDS             14770..18264
                     /gene="mfd"
                     /locus_tag="TVR04_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1269941.1"
                     /translation="MNILELFSQNKSIQTWQSDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEDSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDKIVKKLVKIG
                     YQRVAQVVNPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDVESQKSLQKKD
                     STSIKPASDVIFEPEDFDRAIHNLEKQLQLAKAEHKGYLEELLAITKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDKNATFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKMHSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLETYQCQLPLVSADAIVLRQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGIHRDYVTIQYQQSDRISLPVEQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESIKPMDRLLVGDVGFGKTEVAMRAAFKAVGDHKQVAILVPTTVLAQQHYENFKE
                     RFENYPVEIAVLSRFRSKKEQAESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTIDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMNRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKK
                     EHQVMVRFEAVSLQYYLTQNYFEALSKTSLKARISEHQGKIEIIFDVRGQKDHIILEE
                     LILFGETLGEIKSRKASS"
     gene            18233..19744
                     /locus_tag="TVR04_001250"
     CDS             18233..19744
                     /locus_tag="TVR04_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1269942.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISSFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCCTSFLLSGILV
                     LSHKALASWMGAQQLAPSIIITAMVLLTIPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIAAALCYSVFGWTVYLTANVSAFGNLVASLVILAYLKRYSTYSLKSFFSEDTV
                     AIRDLTSLGLPTLVFLLFSVYLLVFQLVDSLLVKNILVNSGLSELTAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTALFHVEREIYKEQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVIYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYTVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLDVFKEKLWSFLPFVKEK"
     gene            19775..20047
                     /locus_tag="TVR04_001251"
     CDS             19775..20047
                     /locus_tag="TVR04_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1269943.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKQN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRIKSDEEA"
     gene            20034..20405
                     /locus_tag="TVR04_001252"
     CDS             20034..20405
                     /locus_tag="TVR04_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1269944.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            20547..21833
                     /locus_tag="TVR04_001253"
     CDS             20547..21833
                     /locus_tag="TVR04_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1269945.1"
                     /translation="MKKLLAAMLMTFFVTPLKVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSESKSLKYIDEVNHFYGDYDPTGSGK
                     ISKIADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            21830..23113
                     /gene="tilS"
                     /locus_tag="TVR04_001254"
     CDS             21830..23113
                     /gene="tilS"
                     /locus_tag="TVR04_001254"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1269946.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     ELQIRIGIAHVNHKQRPESDAEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHFRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKEELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIALSAESRLLL
                     QAFDDLTKGLAFHRLDCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFVIKKIIPKTDLNRESKMVSYGDPLDYGGYRFAFSGDLTD
                     KGHDIVIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTNEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            23118..23660
                     /gene="hpt"
                     /locus_tag="TVR04_001255"
     CDS             23118..23660
                     /gene="hpt"
                     /locus_tag="TVR04_001255"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1269947.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
BASE COUNT         7313 a         4248 c         4793 g         7306 t
ORIGIN      
        1 ctgctgagat ttttaagcaa tagggcttga cggtttctat tcttttagga gataatgggt
       61 ctattatgtt tactaaacga taaaggaggt attaaatatg aaaaaaaggg taatggattt
      121 actatttgta accatcggct ccttcatcac agctatcggt tttaacacaa tgtttgtcga
      181 taataatatt gcttcaggtg gtatggtggg gatttcagtt gttatcaaag cgctgtttgg
      241 gattagcccc tcgctctttt taatgctaag caatatccct ttattgattt tatgctactt
      301 ctttcttggt aaacaaaatc tcatcaaaac cctctacggt tcatggattt accctattgc
      361 tattcgccta actagccagc ttccaacact cactcataac caattattag cagcgatttt
      421 tggtggtatc atttgtggga tcggccttgg aatggtcttt tggggaaatt catcaaccgg
      481 tggtactggt attctgacac aaatcctaca caaatattct ccattgtcat tgggagttgc
      541 tatgactatt gttgacggca ttagtgtttt aatgggattc atcgccctat ctgctgatga
      601 tgtcatgtac tctacgatcg ggctgctcgt tattggctat gtcattagtg tcatggaaaa
      661 tggctttgac tcttctaaga atgtcatgat tatttcaaag gaatatcagg ccatcaaggc
      721 ttatattaca ggtgttatgg atcgtggtgt ctctaagatt cctatccgag ggggctacac
      781 aacatcagat aagatcatgc taatggctat tgtttctggc tatgagctgc cagctttaca
      841 ggaaaaaatt ctagaaatcg atgacactgc ctttatcgtt gtcatgccag cagcacaggt
      901 catgggacgt ggctttagct taaccaagca ttacaaacta gaggacaaag atgtgctgct
      961 gcctatgtaa gccctaagcc cttttctgat tgaaaaaagg ggctttttta ggtacaatga
     1021 ggattagata aataaaatga ggtgacaaat tgctaacagt ttctgacgta tcactgcgct
     1081 ttagtgatcg aaaacttttt gacgatgtta atatcaaatt tacagctggc aacacttatg
     1141 gcttaattgg tgccaatggt gccggaaaat caaccttcct aaaaattctc gcaggtgata
     1201 tcgaaccaac aacaggtcat atctctttag gaccagatga gcgtctttct gtccttcgcc
     1261 aaaatcattt tgattacgaa gaggaacgtg ccattgatgt ggttatcatg ggaaatgaac
     1321 agctttacag tatcatgaag gaaaaggatg ctatttacat gaagcctgat ttttcagagg
     1381 aagatggtgt tcgtgctgcc gaattagaag gaagctttgc tgagctaggc ggctgggagg
     1441 ctgaaagcga ggcctctcaa ttactacaaa acctaaatat ccctgaggaa ttgcattatc
     1501 aaagcatgag cgagctcacc aatggtgata aggtgaaggt tctcctagct aaagcactct
     1561 ttggcaagcc tgatgttttg ctactagacg agccaaccaa tggtcttgat attcagtcca
     1621 tttcatggct agaggacttc ttgattgact ttgaaaatac cgttattgtg gtgtcacatg
     1681 accgtcactt tttgaacaag gtatgtactc acatggccga ccttgatttt ggaaagatta
     1741 agctttttgt cggtaactac gatttctgga agcaatcatc tgaattagct gcacgccttc
     1801 aggcagatcg taacgccaag gccgaagaaa aaatcaaaga gctgcaagaa tttgtagcac
     1861 gcttttctgc caatgcttct aaatcaaagc aagcaacctc tcgtaagaaa atgctggaca
     1921 aaattgaact agaagagatt attccatcta gccgtaaata cccattcatc aattttaaag
     1981 ctgagcgtga aatgggcaat gactttgtaa cagttgaaaa tttgtctgta accattgatg
     2041 gtgacaaaat tctagataac attagcttca ttctgaggcc aggtgataag actgccatta
     2101 tcggacaaaa tgacattcaa acaacagctc ttatgcgcgc tctggctgat gacattgact
     2161 atgaagggac tatcaaatgg ggagtaacaa ctagtcgctc ctatctgcca aaggacaact
     2221 cacgtgactt tgctagcgat gagtctatcc ttgaatggct ccgccaattt gcagcaaagg
     2281 gtgaagatga tgataccttc ttgcgtggtt tcttaggacg tatgctcttt tctggagatg
     2341 aggttaaaaa atctgttaac gttctctctg gtggtgagaa ggtgcgcgtg atgctatcaa
     2401 agttaatgct tttaaaatca aatgttctcc ttcttgatga cccaaccaat cacctagatt
     2461 tggaatctat ttcaagtctc aatgacggga ttaaagattt taaagagtct gttattttta
     2521 ccagtcacga ccacgagttt attcaaacca ttgctaatca cattgttgtt atttctaaaa
     2581 atggtgtgat tgaccgtatt gacgaaacct atgatgaatt ccttgaaaac aaagacgttc
     2641 aagctaaggt agcagagctt tggaaataag gaagaaacaa ggagctttgc tcaataccat
     2701 cattaaagta tagaaatgat cactgatgac atctgagggc tggaaactat ttctagccct
     2761 tttttcaaaa atatcataga agggcttatt tatgacaaaa cctaaaacat ggtatcttgt
     2821 ttatgacatt gctagcttcc tccttccctt tttgataatg ttttttgttc ttttgtcaat
     2881 gggaatttca tatggcagtg agaaaaccat tttagctagt gatggctttc atcaatatgt
     2941 tatttttgcg caagccctaa gaaatattct tcatggggct gatagtattt tttacacctt
     3001 taccagtggc ctaggtgtaa acttttttgc tctggctagc tattatctag gcagcctttt
     3061 gtctcccctt gtctactttt ttaatctgca atccatgcca gatgctatct atctcttgac
     3121 acttattaaa tttggtttga ttgggcttgc cgcttatttc tcctttcatc gtatttaccc
     3181 taaaatcaaa ccctttttag tcctgacatt gtcagtttct tactccttaa tgagctttct
     3241 aacaagccag ctagagctta ataactggtt agatgttttt attcttctac caattgtctt
     3301 actggggctc tatcggctga ttactcaaac caagccctta ctttattatg gctcacttag
     3361 tcttctcttt atccagcatt attattttgg atacatggtt gctatctttg tttttttatt
     3421 atttctagtc aaccttatat cactagacac atggaaaaga cggttaagag cctgcttaag
     3481 ctttatatca gtgtcaatct tatcagcctt aacaagtgct tttatactca taccggccta
     3541 tctagaccta gcagcctacg gtgaaaaact ctctccaatc aatcagatta tcattaagcc
     3601 tataggagcc tttgatttat tagcaaagct atcacttggt gcctatgata cgacaaagtt
     3661 taatgcgatt cccatgatat ttattggtct gttgccttca ttgttaagta tcgttttttt
     3721 caccttaaaa tctattagct ggcgcttaag gctgggctat gggctgcttt tagggctcat
     3781 catggttagc ttttatcttc agcccttaga tttattttgg cagggcatgc atgcacccaa
     3841 tatgttttta caccgttatt cgtggtcgtt ttcaatcatt atcattattt tagcctgcga
     3901 agccctctct agacaaaaag acattactaa cactagaata gtctttgcct ttatattatt
     3961 aagctgctta ttaacacttc cttatctgac aatggatcaa tatagctttt tacagcctaa
     4021 cttattgatc ttaagccttt cctttttagc ggcatatctt attttattgt taagcatgca
     4081 aaaagactct gtaccaatgc catttttaat cttttttacc ctactgttta gctgtttaga
     4141 aaccagttta aatacctatt atcagcttaa tggcattcat catgaatggg tgttcccatc
     4201 acgtaagggc tatagcagag ctttacagga tattgacaag cttgtcaaga aagcagctac
     4261 taacaacgac cagtttttca gactggagca gctcctgcca caaacaggca acgacagtat
     4321 gaaatacaac tataatggca tttctcaatt ttcatctatc cgaaatcgtc actccagctc
     4381 ccttctggat cgtctaggct atcagtctgc tggaacaaat ttaaaccttc gctatcaaaa
     4441 caacactctc atcatggata gtcttttagg ggtaaaatac aatcttagct accatcagct
     4501 tcataaattt ggcttttcaa ggatagcctc cagtcatcac actacactct atcaaaatca
     4561 ctatagcagc aatctagcta tcttaacaga taacgtttac aaagatgtca agttaactgt
     4621 caacacactt gacaatcaaa ccaagctgct gaatcagctg agtggaaaaa ggctcaccta
     4681 ttttcagcta gagccttcta agctaatatc aaatgctcag gcatttaatg ggagaatttc
     4741 aggggaggct gctgagaata cgtcaacaac cattgttcat tatcaggtta ctgtaccaga
     4801 ccataggcag ctctacttaa gccttccaaa tattagcttt tcaaatcaca atacaacagc
     4861 tgttaggatc cgtattgatg atcagaccta cgagtacact actgacaacg ctttttcatt
     4921 ctttgactta gggtactttg aaaaaggaag aaccttaacc cttgctatta tgtttccgaa
     4981 aaacaaaaat atttcctttg ctaccccaca cttctacagt ttaaatagtg acaactatct
     5041 ggcagccatg aatgcgatta accaaaaaga ggttactact tacacccgta gcaatcaggt
     5101 catcagccat tacaaggcca aatcagaagg ctctatgatt tttacccttc cctatgacaa
     5161 aggctggaca gcaagactaa atggccgacc agtggctctt aaaaaggctc aaggtggttt
     5221 tattaggata gatgttccaa aaggatctgg taaattagta ctcacctttg ttccaaatgg
     5281 ctttacatta ggcttattgc tctcatttat tggtatcttg ctttacagct tcttacatta
     5341 ctacttactc aggtaaacag ccaagctaaa agcttaaaca gcaatttcca tatataagca
     5401 aaacgcttga ttttacagcc cttacaggta tcaaaatcaa gcgtttttag ctggtctatt
     5461 ggtttaagga tattaaagta cagagctttc catagatcac gtgtccctta gtaaattaca
     5521 atctctcttc aaggtcaata aaaaaatcct aagaaaacct taggatgtgt cttatcactc
     5581 cggcagtagg actcgaacct acgacatcat gattaacagt catgcgctac taccaactga
     5641 gctatgccgg aaaataaaaa aattgccaca atgacaattc tgatagtccg tacgggattc
     5701 gaacccgtgt taccgccgtg aaaaggcggt gtcttaaccc cttgaccaac ggacctgaag
     5761 cttaggagta actctcctta acactcttat tattatagca gaatgttttt atttgtctat
     5821 acttttttca aaaaaatctt gattttttga tcacttttga cataaacaac ctaaaataaa
     5881 tctaatcacc ccaaacatgc tagaaaaaat aacatatgtc tcttctgaca cagactacta
     5941 aaagacacac cgctacaggt ttggggcagt gaagcatctt atcaaaaata agcattgaca
     6001 ggcataaggt ttttttgtta aaatgaagtg gttgaggtct catagctcag ctggatagag
     6061 cattcgcctt ctaagcgaac ggtcgcaggt tcgaatcctg ctgagatcag aatacttaaa
     6121 aatgccatta gtcaatagct agtggccttt ttgtattttt agcaatagca agctgctgac
     6181 tcccgtagga gagtcagtaa gagtgatagt acttatctga catcgtctaa ggctaaaatc
     6241 acaaaacctc caaatcgcca gctttgtaaa gctataatgg cagtagctga gtaaaactac
     6301 aaattagcag ccctattaat gaaagctaga aatatggttg aggtatacac gcgcttcttc
     6361 tatgccatgt gtggtgtttc atgtgaaaca actgctattt atgatatgga ctgccttgtt
     6421 gaatcataaa agcacgataa acctgctcga ttaaaaccaa acgcatcaat tgatgaggta
     6481 aggtcaatag gccaaagctc atcaataaat tagccctatt tttaatggat tgatccaaac
     6541 caagactccc accaatgaca aaggcaatgt ctgaatagcc ttttacagtg acctctgata
     6601 gtagatgact aaactgttct gatgccaatt gcttgccctc tattgccaaa gcaattacaa
     6661 aatcacgctg accaagcttt ttcttgatcc tgtcagcctc cttagccata atctgctgtt
     6721 tttcagcatg gctagcctta tcaggtgttt tttcatctgc taattcaatg atatcacatt
     6781 ggcaaaagcg agacagtctt ttttggtatt ctgcaatccc atctcttaaa tacgcttctt
     6841 ttaattttcc gacacaaata agctttattt tcatatcctt attgtaccat aatcaactct
     6901 ttttacacag cttatccaca tgttgatttc ttattttctt tatataaacc cttttctaca
     6961 gcctttttag tatagtcctg aaaagttttc cacaagttgt ggattacttt tcttttttat
     7021 ggttttaagg tataattaag tgaggtttta tatcctatgt gaaaaccatt cggaggtgat
     7081 tttgtgttaa aatcaaaaaa tatattgaag cccttatggg ttttagccat tggattttta
     7141 gggggcttat tagctgcctt agttgttaat ggatttagtc agaattctct aacatcttca
     7201 aatgcaaagg gagcaacgac aacaagcaac gtcagcttta ataatacaac tgatacaaca
     7261 aaggctgtta aggtggttca agatgctgta gtgtctgtta ttaactatca aaaggctgct
     7321 tcgcctgcca tttcaaatcc ttacatcaat cttttcggag aagaaaatga tacctcagca
     7381 gtacaaaaag aggacgagct aagcatacac agtgaaggct cgggtgttgt ctacaaaaaa
     7441 gaaggaaata ctgcttatct tgtaaccaac aatcatgtta ttgagggagc tcaacgaatt
     7501 gaaattttaa cagcagacgg ctctaagatc gttggagaac tagttggtgc agacacttat
     7561 tctgacctag ctgttgtcaa agttgctgct gataaaatca aaacaatagc caaatttgca
     7621 gattcaacca aaattaatgt tggagaggta gccattgcaa ttggtagtcc tcttggaaca
     7681 aaatatgcca actcagtgac agaagggatt gtttcaagtc taagccgtac agtcacttca
     7741 agaaatgagg caggcgagac catctcaaca aatgctatcc aaactgatgc tgctatcaat
     7801 ccaggtaatt caggtggacc actcatcaat attgaaggcc aggttattgg tatcaactca
     7861 agtaaaatat cctcaacacc tactggtagc ggcggagcca ttgagggaat tggctttgct
     7921 attccatcaa gcgatgttgt caccattatt aaccaactag agtctaacgg agctgttatc
     7981 agaccagcct taggcattac aatggtaaac ttaagtaatc tatcaaccaa tgcattgatt
     8041 caattgaata ttccaacaag cgttaccagc ggtgttgtcg tagcctctac tcaagatggc
     8101 atgcctgctc ttggtaaatt ggagcagtat gatgtcatta ctgaggttga cggtaaagaa
     8161 gtcagctcaa ttagtgacct acaaagtgtc ttatatagtc atgagattaa cgacaccatt
     8221 aaggtaacct tctacagagg aactgctaag aagaaagttg acatcaaatt aacaaaaaca
     8281 actaaggatc taactaaaaa gcagtaaaca ttgggtatcc ccgtgagatt gagtccgaga
     8341 cgatagtcgc gggctcttgc tcttttatcc catatgtatc tctaataacc gttaagctac
     8401 cactatttcc cttttgagag gcttatatga cagaaatcct aatgcacatt cctatcgagg
     8461 atattgtggc aaatccttat caaccacgtc ttcaatttaa tcaaaaagag cttgaggagc
     8521 tggcacattc cattcaggct aatggtttga ttcaaccaat cattgtcaga aaatctgatg
     8581 tatttggcta tgaattagtc gctggagaac gacgctttaa agcagccaag ctggcaggac
     8641 ttcaaaagat tccagcaatt gttaaggaaa tctctactct tgagagcatg cagcaggcca
     8701 tcgtagaaaa cctacagcgc tcaaatttaa atgctattga agaggctaag gcctatcaat
     8761 tacttattga taaaaataag atgacccatg aggacatcgc gacatacatg ggaaaatcac
     8821 gcccttatat cagcaacacc atcagactgc tgcaattacc agacgttatt agacaagcga
     8881 ttgaggacgg taccattagc gccggccatg caagagcttt attatccttg tcaacatcaa
     8941 aagagcagga gctgtatttt cacaacattc tggatcaagg cttaagcgtt aggcaaatcg
     9001 aacagctggt aaagactaag catccccaaa aaaaaagaaa caaacataaa accatttttg
     9061 tgaagtcttt agaaaaagag ctctcaaaat cattaggatt acctgtggca ttgtctctcc
     9121 aaaaaaatga cagtgggcag ctgcaactgt cattttcaaa ccaagaagaa ttgaacagaa
     9181 ttatcaacaa gctgctttag cttgttgatt gtctgttttt tttattcagt tttccacaag
     9241 agaaatgggg ctaaaacctt ttagtcacaa ggctttctct tttttccaca agttgtggaa
     9301 aactatcttg cacattgtgt attttatctc cacagcttgt gggtaagtct aaaataatcc
     9361 ttgatccttt gtggaaaact atctttattt atgatagaat ggttctagaa ttatccacaa
     9421 gaaggaatct catatgactg aaaatgaaca aattttttgg aatagggtct tagagctagc
     9481 tcaaagccag ttaaagcagg caacttatga attttttgtt catgatgctc gtttgatcaa
     9541 ggtagacaat catgtcgcaa caattttttt ggatcagatg aaggaattgt tttgggaaaa
     9601 aaatctcaaa gacgttatcc taacagcagg atttgaagtt tacaatgctc aaattgctgt
     9661 agactatgtc tatgaggatg acttgatgat tgagcaacag catcagggac agcaaggata
     9721 tactgaacaa gcctttcagc aattaccaac agtacagtcc gatttaaacc ctaaatacag
     9781 ctttgacaac tttatccaag gtgatgaaaa taggtgggct gttgctgcat caatagcggt
     9841 agctaataca ccaggaacaa cctataatcc tttatttatc tggggaggtc caggtcttgg
     9901 taagacccat cttttaaatg ctattggaaa ttcagtttta ctggaaaatc caaatgctag
     9961 gattaaatac attacggctg aaaattttat taatgaattt gttgttcata ttcgtctaga
    10021 tactatggac gagctaaagg agaaatttcg caatcttgat ctcctcctaa ttgatgatat
    10081 tcaatcccta gctaaaaaaa ccttgtctgg tacacaagag gagttcttta acaccttcaa
    10141 tgctctacat aacaacaaca agcaaattgt tttaacaagt gaccgaaccc ctgatcacct
    10201 caatgaccta gaagatcgcc tagtgactcg atttaagtgg ggactaacag ttaatatcac
    10261 accgcctgat tttgagacac gtgttgctat tttgaccaat aaaattcaag aatataattt
    10321 catctttcct caggacacca tcgaatattt ggccggtcaa tttgactcta atgtcagaga
    10381 cctggagggg gctttgaagg atattagtct tgtggctaat tttaaacaaa ttgatacaat
    10441 tacagtagac atagcagcag aagctattcg agctagaaag caagacggtc ctaagatgac
    10501 tgtcattcca attgaagaaa tccaagctca ggttggaaaa ttttatgggg ttacggttaa
    10561 ggaaatcaag gcgaccaaac gcacacagga tatcgtgctt gctagacagg ttgctatgtt
    10621 tttagctcgt gagatgacag ataatagtct accaaaaatc ggtaaagaat ttggaggacg
    10681 tgatcattca actgtgcttc atgcttataa caaaataaaa aacatgattg gacaagacga
    10741 gagcctcaga attgaaattg aaaccatcaa gaacaaaatc aaataagcaa tgtggataac
    10801 ctttagcaaa aaggaaaatt tatccacagc ttgtgcacaa gcgttttaac tagtaacgac
    10861 tggtacaagg agacttatcc actattttaa caagacctac tactactact agctataata
    10921 cttatataac aaaggagtta ccatgattca attttctatc aatagagccc ttttcattca
    10981 agctttaaca gccactaaaa gggctatcag cagtaaaaat gctataccga tcttatcaac
    11041 catcaagatt gaggttaatc catcagacat taccctgact ggctctaatg gtcaaatctc
    11101 tattgaaaat accattcctg ttagcaatga aaacgcaggc ttgttgataa cctcaacagg
    11161 ggctgttctt ttagaggcca gcttttttat caatattatc tcaagtcttc cagatgttag
    11221 cttagaattt aaggaaattg aacagcatca ggtggtgcta accagtggga aatctgaaat
    11281 caccttaaag gggaaggatg tttctcaata cccacgtctt caagaggtat caactgaaaa
    11341 tcctttaatt ttaaatacaa gactcttaaa atctatcatt gctgagacag cctttgctgc
    11401 tagtatgcag gaaagtcgtc ctattttgac aggtgtacac attaccttaa gtcaacataa
    11461 ggacttcaaa gcggtagcaa cagattcaca tcgtatgagt caacgtttga ttactttgga
    11521 taaaacctca gccgattttg atgtggtcat tccaagtaaa tccttgagag aattttcagc
    11581 tgtctttaca gatgatatcg aaactgttga agtgttcttt tctgctagtc aaatgttatt
    11641 tagaagcgac tacatttctt tttacacccg tctattagaa ggtaattatc ctgatactga
    11701 ccgtttgctg atgaaggatt ttgagacaga ggctgttttt aacacacaat ccttacgaca
    11761 tgctatggag cgtgctttct tgatttcaaa cgctacgcaa aatggtactg ttaagcttga
    11821 aattgaagca aatcgcattt cagctcatgt taactctcca gaggttggta aggttaacga
    11881 ggatctggac gtggtgagtc aagcagggaa tgatttaacc attagcttta acccaaccta
    11941 tctgattgaa gccttaaaag ccattaaaag tgagactgtt aagattcact tcctatcgcc
    12001 tgttcgtcct ttcaccttaa caccgggaga tgatgaagag agctttatcc aattaatcac
    12061 accagttcgt acaaactaag cgaaaaatgc tcccttttag gagctttttt tgttatgata
    12121 aataataaat ataagagatg agtgagtgat aaagtgatgt atcaagttgg atccttaatt
    12181 gaaatgaaaa agcctcatgc ctgtgtcatt aaagaaacag gaaaaaaggc aaatcaatgg
    12241 aaaatcacaa gagtaggagc agatattaag ttgcaatgca ctaactgtaa tcatgttatc
    12301 atgctaagtc gtcatgattt tgagcgtaag atgaagaggg tcttgcaacc atagaagctc
    12361 tattgtcata aggtttttaa ctaccttcgc aaccaattat tgcgtcaaaa attgctagct
    12421 tgccttttaa aaaagagtta ttgtaaaggt atcaaaaagg aaaggcggtc attaatgatg
    12481 actaaattcg cagaacaatt aaagaagtat cggcttgaaa agcagttgtc gcaggacgcc
    12541 ttagctgaga agcttttcat ctcccgtcag gctatttcaa agtgggaaaa tggagatgcg
    12601 acaccggatt tggaaaattt agttacattg gcagctgttt tagaggtgac tttagatgaa
    12661 ttggtgactg gaaaagagtc tgcaatcaag gttaccaaga aaactgaaaa accaatgaac
    12721 gtatgggaat ttttaactga ggaatctaaa cggccaataa gtaaaggtga tcttctcatg
    12781 ctgttattgg ttccgattgt cttgttgggt gtgtatctta ttgtgatcta ttttagttaa
    12841 agatcattac taggcaagct ttttcttctt ttttttgcta taatgatagg gattgaaaaa
    12901 atgtaacgga gaccgaaaaa aatatggctt taacagcagg catcgttggt ttgccaaacg
    12961 ttgggaaatc aaccttattt aacgcaatta caaaagcagg ggcagaggct gctaattatc
    13021 cttttgcgac aattgatcct aatgttggta tggtagaggt tccagatgag cgtttacaga
    13081 agttgacaga gcttatcacg cctaaaaaaa cagtacctac aacctttgaa tttacagata
    13141 tcgcaggtat tgtaaaggga gcttcaaaag gagaaggact tggaaataag ttcttagcca
    13201 atatccgcga ggttgatgct attgttcatg tggttcgtgc ctttgatgat gaaaatgtca
    13261 tgcgtgagca agggcgtgag gatgcctttg tggatccttt ggcagatatt gatacgatta
    13321 accttgaatt aattttggct gacttagaat caatcaataa acgctatgcg cgtgtcgaaa
    13381 aaatggcccg tacacaaaag gacaaggatt ctgtagcaga atttgctgtt cttgaaaaaa
    13441 ttaagccagt gcttgaagaa ggtaaatctg ctcgtaccat tagctttaca gatgatgagc
    13501 aaaaaattgt taggcagtta tttttattaa cgactaagcc agtgctttat gtggcaaacg
    13561 ttgatgagga taaggtagca actccagacg ctattgatta tgtgaagcag attcgtgact
    13621 ttgcagcaac tgaaaacgca gaggttgttg tcatttcagc tcgtgcagaa gaagagattt
    13681 cagagctaga tgatgaagat aagctcgaat ttttagaggc tatcggtctg acagaatctg
    13741 gcgttgacaa gctgacacgt gcagcctatc atttacttgg acttggcacc tactttacag
    13801 ctggtgaaaa ggaagtgcgt gcatggacct tcaagcgcgg cattaaggca ccacaagcag
    13861 ctggtatcat tcactcagat tttgagcgcg gttttattcg tgcggtgacg atgagctatg
    13921 atgatttgat taagtatggc tcagaaaagg ctgttaaaga ggcaggtcgt ctgcgtgagg
    13981 aaggaaagga atatatcgtt caggatggcg atattatgga atttagattc aatgtttagt
    14041 ggtaacaata tcgtgttcta gggttgggat agtattccag cccttttggt gcctatcaaa
    14101 agcttagaaa ggacaaaaaa tagaggggaa gaggctgata aagctttaat aatgatagca
    14161 ggctgctatc atacctcgtt tctctggtgt attagttatg gtaaaaatga ttgtaggatt
    14221 aggaaatcca ggctcaaaat atcagcaaac aaagcataat gttggtttta tggcagttga
    14281 cagaattgtc aatgatcttg acattagctt tacagaagat aaaaccttca aagcccttgt
    14341 tgggagtact tttatcaatc aagaaaagat ttattttgtt aagccaacta cctttatgaa
    14401 taatagtggt cttgctgtta gagctttatt gacctattac aatatttcaa ctaaagattt
    14461 aatggtcatc tatgatgatt tagatatggc agttggtaaa attcgtttgc gtcaaaaagg
    14521 ctctgcaggg gggcataatg gtattaaatc cattattgct catatcggta cacaggaatt
    14581 tgatagggtt aaaattggta ttggaagacc aagtcatgga atgagtgtta ttaatcatgt
    14641 tctaggaaaa tttgatacag atgatatgat aacaatcaat atagcacttg ataaggttga
    14701 caaagcaatc aactattatt tacaggaaaa aagcattgag aaaacaatgc agcaatttaa
    14761 tgggtagtta tgaatatttt agaattattt agtcaaaaca agtcaatcca gacctggcaa
    14821 agtgatgtta caagcttaaa acggcaatta gtcatggggt tgtcaggctc aagtaaagcc
    14881 gcagctattg cctcagccta tcttagcttt caagggaagc tggtcgtggt gacgtcaact
    14941 caaaatgaca tggaaaaatt agctggtgat ctgtcagcct tgcttgatga ggactctatt
    15001 tttcaatttt ttgcagatga tactgctgca gctgagttta ttttttcgtc tatggataaa
    15061 acaatctcta gaatagaagc actagctttt ttatcaaatc cagaagcaag aggaatattg
    15121 gtcataagct tagcaggact cagaatccta cttccaagtc ctaagacttt tcagcagggt
    15181 cagattgact tagcagtagg agttgacact gatcttgaca agattgtcaa gaagcttgtc
    15241 aagattggtt atcaaagggt agctcaggtt gttaatcctg gtgaatttag cagacgaggc
    15301 gatattttag atgtttacga ggtaacacag gacttgcctg ttcgcatcga attttttggt
    15361 gatgagattg atggtattcg gagctttgat gtagaaagtc aaaaatctct ccaaaagaag
    15421 gatagcacca gtatcaagcc tgcaagtgat gtgatttttg agccggagga ttttgatagg
    15481 gctatccata atcttgaaaa acagcttcag cttgctaagg cagaacataa aggctatctg
    15541 gaggagctgc tcgccataac aaaagaaggc ttgaagcata aggatattcg taaatttcaa
    15601 tcactgtttt atgataatga atggacaatt ttagattatc ttcctaaggg aacaccagta
    15661 ttttttgatg atttccaaaa gttagttgac aaaaatgcta catttgactt agagcttgct
    15721 catttgttga cagatgattt acaacaagga aagtcacttc catttctcca ttattttgct
    15781 gacaattatc gtgagctgcg acactataag cctgccacct tcttttcaaa ttttcacaag
    15841 gggcttggta atattaaatt tgataaaatg cacagcttga cacagtatgc catgcaggag
    15901 tttttcaatc aatttccatt actcattgat gagattaagc ggtatcaaaa atcaggagca
    15961 actgttcttt tacaggttga atctcatcag gcctatgaac ggttggcaaa atcccttgag
    16021 acttatcaat gtcaattgcc ccttgtttct gctgatgcaa tagtattacg tcaagcacag
    16081 atcattattg gtcacctagc aggtgggttt tactttgctg atgaaaaatt agttttaatc
    16141 actgagcatg agatatatca taagaggctg aagcgtcgtg ctcgtcgtac caatatgagt
    16201 aatgctgaac gcttaaagga ttacaatgaa ttgtctaagg gtgattatgt ggttcacagt
    16261 gtgcatggga ttggtcgttt tttaggcatt gaaacgatta atatacaagg aatacatcga
    16321 gattatgtca ccattcagta tcagcagtca gatcgaattt ctttgcctgt tgagcagctt
    16381 gaaagcttat cgaaatatgt gtcagcagat ggtaaagagc caaagattaa taaattaaat
    16441 gatggtcgtt ttcaaaaagc aaagcaaagg gttaaaaagc aggttgagga tattgcagat
    16501 gacctgttga agctttatgc agagcggagt cagcaaaaag gatttcagtt ttctccagat
    16561 gatgagttac aaagagcatt tgaggaggat tttgcctttg ttgagactga tgatcaagtt
    16621 aggtccataa aagaggttaa aaaggatatg gaaagtatca agcctatgga ccgtttgcta
    16681 gttggtgatg ttggctttgg taagaccgag gtagctatga gagctgcttt taaggctgtt
    16741 ggtgaccata agcaggtagc tatcctagtg ccaacaactg ttttggcaca gcagcattat
    16801 gagaatttta aggaaagatt tgaaaactat ccagttgaaa ttgctgtctt aagccgcttt
    16861 cgcagtaaaa aggagcaagc tgaaagtcta gaaagactaa aaaagggaca ggttgacatt
    16921 attattggga ctcataggct gctgtcaaag gatgtgattt tttcagattt aggcttgatt
    16981 gtcattgatg aagagcagcg ttttggtgtt aagcataaag aaaccctaaa ggaattaaag
    17041 accaaggttg atgtccttac actgactgca acacctattc ctcgtaccct gcatatgtct
    17101 atgcttggta ttcgggattt atcagtgatt gagacgcctc ctacgaatcg ctatcctgtt
    17161 cagacctatg ttttagaaaa caatcctggc ttgattagag aagctattat tcgagaaatg
    17221 gatcgtggtg gtcaagtctt ttatgtttac aataaggttg acacgattga caagaaggtg
    17281 gcagagctgc aagaattggt tccagaggct tctattggtt ttgtccatgg tcaaatgagt
    17341 gatattcagc ttgagaatac cttgatggat tttatcaatg gtgattatga tgtcttagtt
    17401 gcaacaacta ttattgagac aggggttgat atttctaatg tcaatacctt gtttattgaa
    17461 aatgctgatc atatgggact atcaaccttg tatcagcttc gaggtcgtgt tggaaggagc
    17521 aatcgtattg cctatgctta tctcatgtat aagcctgata aggtactaac agaggtttcc
    17581 gaaaaaaggt tagaagctat taagggcttt acagagctgg ggtctggctt taaaattgct
    17641 atgcgagatt tatctattcg gggagcagga aatatattgg gtgcttcgca aagtggtttt
    17701 attgactcag ttggctttga catgtattct cagctgctag agcaggctat tgcaagtaag
    17761 caaggaagag cgttgacgcg acaaaaaggt aatgcagaga ttaatctcca tattgatgct
    17821 tatttaccta gtgattatat caaagacgag cgtcaaaaaa ttgacattta taagcgcatt
    17881 cgtgagattg actctagagc agcttattct gatttgcaag atgaaatcat gaatcgtttt
    17941 ggtgactatc ctgatcaggt agcctattta ctggagattg gcttgttgaa atactacttg
    18001 gatacagcct ttgctgaatt agtcgagaag aaggagcatc aggttatggt taggtttgag
    18061 gctgtctcgc ttcagtacta tttgacacag aattattttg aagctctgtc aaaaacaagc
    18121 ttaaaagcaa ggattagtga gcatcagggt aaaattgaaa ttatctttga tgttaggggt
    18181 caaaaagacc atatcatttt agaagaattg atactttttg gagagacact tggtgagatt
    18241 aaatctagaa aagcttcctc ataaaactaa gcaatcaagc cttttgattg ttatcagtag
    18301 ctttatgtca aaattattag cagccagtta ccgtatccct tatcaaaatt tagtagggga
    18361 taggggcttt tatgcttacc aacaaatcta tcctttgcta ggtattattt cagctttagg
    18421 tctaactgcc ttacccaatg tgattgccag tatggcccag aaaaaaaaac agctacagct
    18481 agcagctcta tttaaattgc aatgttgtac cagcttccta ttatcaggaa tattggtgct
    18541 gagtcataag gcattggcta gctggatggg ggcacagcag ctagcaccat caattatcat
    18601 aacagcaatg gttttgttaa caatcccctt tatatccttt tatagaggtt tagcccaggc
    18661 tgatatgaat atggctccaa cagctctgag tcaggttctt gagcagatca taagagttgc
    18721 tataatcatt gctgctgctc tatgctacag cgtgtttggt tggacggttt atttaacagc
    18781 aaatgtttct gcttttggaa atttagtagc gagcttagtt attttagctt atctgaagcg
    18841 ctatagcact tattcgttaa aaagcttttt ctcagaagat acagttgcta ttagagattt
    18901 aacaagtctg ggcttgccga ccttagtttt tttacttttt tcagtttacc tgcttgtttt
    18961 tcaattggta gattctcttt tggtgaaaaa tattttggtt aattcaggct tatcagagct
    19021 aacagctgaa atgactaagg gtgtttacga taggggacag cccttgctgc aatttggtct
    19081 cattttttcg acagccttat ttacagccta tttaccgaat ttaacagcct tatttcatgt
    19141 tgaaagggag atctataaag aacagagtca atgtttcttt gagtttatct tttattttag
    19201 cctgacgttg actgttggct ttattagtat tcttcatctg atgaatcgag ccttatttga
    19261 ggacaataag ggctggctgg ccttagtgat ttacctgatg attatagcag tgtcaagtat
    19321 gattcaattc tttcatcaaa aatgcttcat tgaagatcac atcaagcagt ctttgcttat
    19381 tttgctgttt ggctttttat taaaattagg cttaacacct atattaactt actattacgc
    19441 tattgttgga agctccttat caactctaat ccccttgctg gtcgttttac tcctatatac
    19501 tgtgctggct gatattgatt ttaaagcgat agtgaatgct aaatatgggc ttgctttagt
    19561 gatcatgctc atgtgtgtgc ttacaagtca gtattgtttg ccattatcag gtcggcttgg
    19621 tgcgctgatt agtcttttgg tgtcatctgc tgttggttta tcctcttttt taatagcttg
    19681 caaaaagcta gatgtcttta aggagaaatt gtggtctttt ctaccatttg tcaaagaaaa
    19741 atgatagaat gaaagggatt gtgaggcaaa agatatgaga ttagataaat atttaaaggt
    19801 atcaagattg attaagcgtc gatcagtggc caaagaggtt gcagataagg gacgtattaa
    19861 ggttaatggt atccttgcga aaagctcaac tgatttaaaa caaaatgatc aggttgaaat
    19921 cagatttggc aataagttgc tgactgttcg tgtgcttgac atgaaggaca gcacgaaaaa
    19981 agaagatgct gctaaaatgt atgacattat cagcgaaaca aggataaaga gcgatgaaga
    20041 agcctagtat cgtccagttg aataaccatt atatcaacga agaaaatatc aaaaaacggt
    20101 ttgaggaaga ggaaattcaa aaacggaacc gttttatggg gtggatcttg gttagtatga
    20161 tgttcttgtt tattctgcca acttataacc tggtcaagag ttatgtttca ctgaaaaaac
    20221 aaggtcagca gattattaca ttggaaaaag agtatcgtga gttagaaaaa aagactaagt
    20281 ctgaaaaaca gttagctgag cagctaaaaa atgatgattt tgtcaaaaag tatgctaggg
    20341 ctaaatatta cttatcaaga gaaggagagg ttatttatcc aactcctgga ttattaccaa
    20401 aatagtaatt gactatggat aatattgtcg aaaaaattga aacatttctt gccttttctg
    20461 atgacaaatt agcagagcta gaaaaggaaa atcaaaagct gaagaaagac catcatcaca
    20521 caaaagtaaa ataggaggga gccattgtga aaaaattatt agcagctatg ttaatgacat
    20581 ttttcgtgac tcctttgaag gtcattagta cagaaaaaat tccagtgttt tctgaagcaa
    20641 cacgatacca tttaagtcag gatattgtta gctctactct ttattatagt cggattccga
    20701 ctaatcccaa tgtttttgag gagacagttg cttataggga tcccgaattg agtgtgccaa
    20761 agacgatgat cgcaccagac aatagaattg ttatcaagga tgttttgcta aacaaggcag
    20821 ctattcctgt ctttagactg gcagatgaca cttaccttga agctagtcgt cagattgttt
    20881 acgaggatat tatgtttgag cagacagctg tggatttgga tttttggact caaaaaaaga
    20941 tgactatata tgctgaaccc tatgttttag gtgttaagac aattgcatca gatagtgagc
    21001 ctggcagaaa ggttcatgct agtaagatgg ctcaaacaga gcatgggacc tattatttca
    21061 ttgatcataa gggctgggtt aatcaaaagg agttgtcacc taccgacaat cgcatgttga
    21121 aggttcagga aatgctattg caaaaatata ataaagagaa ttattctatt tttgtaaagc
    21181 agcttaacac gcaggccagt gcaggtatca atgctgataa acagatgtat gcggcaagta
    21241 tttccaaatt agcaaccctg tacagtgttc aaaaaaaact aaagtcaggt agcttatctg
    21301 aaagcaagag cttaaaatac attgatgagg tcaatcattt ttatggtgat tacgatccaa
    21361 ccggcagtgg taaaattagt aaaatagctg acaaaaagga ctataatgtg atggagcttt
    21421 taaaggctgt ggctcagcag tctgacaatg ttgctactaa tatcttaggc tactacctat
    21481 gtaatcaata taatcaagcc tttcaatcag agattcgggc tctagctgga gtagattggg
    21541 atatggaaaa gcgcttgctt tcttctcatg cagcagcaaa tctcatggaa gctatctatt
    21601 atcaaaaagg tcagattatt tcttatttgt cacagacagc atttgatgat cagcgcattt
    21661 caaaaaatat ttctgtgcca gtggctcaca agattggaga cgcctacgat tacaagcatg
    21721 atgttgccat tgtttatggt gataatccct ttatcttatc cgtttttaca gataaggctt
    21781 cctatgacga catcacagca attgctgacg atgtttattc gattttaaaa tgacttatca
    21841 acacatttat aacatcataa aaaagaaggc ctattttgat gctcatcagg ctgttttgat
    21901 agctgtatct ggtggagtag attcgatgaa tttgctgcac tttttgcatg cttttcaagc
    21961 agaattgcaa attcggattg gcattgcgca tgtcaatcac aagcaaagac cagaatcaga
    22021 tgccgaagag gcttatttga ggtcttgggc taaaaagcat gctattccta tctatgttgc
    22081 ttattttcag ggcgcttttt ctgagaatgc tgcgcgtcat tttcgctatc aattttttga
    22141 agaaatcatg cagcaggagc attattcggc tttagtcaca gcacatcatg ctgatgatca
    22201 ggctgagact attttgatga gactgattcg tggtagtcga ttgcgtcatt tagctggtat
    22261 cagagaggtt cagccctttg ctaatggtca attgatacga ccgtttttaa cagtatcaaa
    22321 agaagagttg cctaatccct ttcattttga agatcattct aatgacagca tggcttattt
    22381 tcgcaatcgt gttcgtcatc attacctgcc agatttcaaa agagaaaatc ctcaggctac
    22441 tcaatctttg attgctttat ctgcggaaag tcgcctgctg cttcaggcct ttgatgattt
    22501 aacaaaagga cttgcatttc accgattaga ttgtttttta gctcaatcag ctgctgttca
    22561 gttttttttg cttcagcatt atttagaaac gtttccgcag ctagctatta aaaaatcaca
    22621 atttgatgat cttttacaca ttatcagacg gcaaaagcag gggatttatc caattaaaaa
    22681 tacttattgt ctcctcattg aaaaagagtc ttttgttatt aaaaaaatca ttccaaagac
    22741 tgatttaaat cgagaatcaa aaatggtatc atacggtgat cctttagatt atggagggta
    22801 tcgatttgct ttttcaggtg acttgactga caaaggacat gatatagtta ttcctttata
    22861 tagcttatca ccagttacct tgcgtcacag gcaggcagga gatcggcttt ttcttggtga
    22921 attttcaaaa aaattaagac gattgtttat cgatggaaag tttacaaacg agcagcgtca
    22981 aaatgccatc gtaggagaac aggccggagt tattattttt gtgctggttg gcgatgaaac
    23041 atatttgaga aaagcatcta aacatgatat aatgttggct aaactgtata ttgataaatt
    23101 agaaaaaagg tgacagtatg cttgagcaag atattcaaaa aattctttat tctgaaaatg
    23161 acattattca aaggaccaaa gagcttggtg agcagttgac gaaggattat catggtaaaa
    23221 atccattgat ggtcggtgtc ttaaagggct ctgttccatt catggctgag ctcatgaagc
    23281 acattgacac tcacgttgaa attgatttta tggttgtttc tagctataat ggtggaacaa
    23341 ctagcagtgg agaggttaaa atcttaaaag acgttgacac caatattgag ggaagagacg
    23401 tcatctttgt tgaagatatt attgatactg gtcgaacact caaatatttg cgtgacatgt
    23461 tcaaatatcg taaggctaat tccgttaaga ttatcacact atttgacaag ccagagggtc
    23521 gtgtggtaga cattgaggca gactatgtgt gctacaatgt tcctaatgag tttattgtag
    23581 gcttcggatt agattacgca gaaaattata gaaatctccc ttatgtcggt gttttaaaag
    23641 aggaagtcta ttcaaaatag
//
LOCUS       DARYSY010000035        23531 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYSY010000035 DARYSY010000000
VERSION     DARYSY010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23531
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            475..741
                     /locus_tag="TVR04_001256"
     CDS             475..741
                     /locus_tag="TVR04_001256"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269948.1"
                     /translation="MKRLKTLCFLATAITLTLAPISTSQTQPQTVYASAVVIKDYNNG
                     YRYFDENNGQTMRATSFEGRRRSWRDSILDLLERVWNTVVKWLF"
     gene            971..2455
                     /locus_tag="TVR04_001257"
     CDS             971..2455
                     /locus_tag="TVR04_001257"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1269949.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVGRKIAILTATSGDTGKAAMAGFADVPGT
                     DIIVFYPKSGVSRIQELQMITQASHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     RQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLAAGEVINIVVPTGNFGNLLAAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     HLLGNDAQKTASLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2495..3796
                     /locus_tag="TVR04_001258"
     CDS             2495..3796
                     /locus_tag="TVR04_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1269950.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGIIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKGIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLLTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYVWGFGVIGIAWSTVVSRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TTTVILVANQLGSGKGATIAKTVKETFLLTTLMMLVVGLITYLLGPGLLPLFTADVKA
                     QQAGMVVLTFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTVGMWLVRISLGYFIGV
                     TLDYGLIGVWLATILDNATRWLILAVAFKKQQKLLSSDCHS"
     gene            4174..4482
                     /gene="rpsJ"
                     /locus_tag="TVR04_001259"
     CDS             4174..4482
                     /gene="rpsJ"
                     /locus_tag="TVR04_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1269951.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4780..5406
                     /gene="rplC"
                     /locus_tag="TVR04_001260"
     CDS             4780..5406
                     /gene="rplC"
                     /locus_tag="TVR04_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1269952.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            5431..6054
                     /gene="rplD"
                     /locus_tag="TVR04_001261"
     CDS             5431..6054
                     /gene="rplD"
                     /locus_tag="TVR04_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1269953.1"
                     /translation="MANVKLFDQTGKEVSTVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            6054..6350
                     /locus_tag="TVR04_001262"
     CDS             6054..6350
                     /locus_tag="TVR04_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1269954.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            6368..7201
                     /gene="rplB"
                     /locus_tag="TVR04_001263"
     CDS             6368..7201
                     /gene="rplB"
                     /locus_tag="TVR04_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1269955.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKIGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLIVRRRNE
                     K"
     gene            7313..7591
                     /gene="rpsS"
                     /locus_tag="TVR04_001264"
     CDS             7313..7591
                     /gene="rpsS"
                     /locus_tag="TVR04_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1269956.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7607..7951
                     /gene="rplV"
                     /locus_tag="TVR04_001265"
     CDS             7607..7951
                     /gene="rplV"
                     /locus_tag="TVR04_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1269957.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7964..8617
                     /gene="rpsC"
                     /locus_tag="TVR04_001266"
     CDS             7964..8617
                     /gene="rpsC"
                     /locus_tag="TVR04_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1269958.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8621..9034
                     /gene="rplP"
                     /locus_tag="TVR04_001267"
     CDS             8621..9034
                     /gene="rplP"
                     /locus_tag="TVR04_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1269959.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            9044..9250
                     /locus_tag="TVR04_001268"
     CDS             9044..9250
                     /locus_tag="TVR04_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1269960.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            9275..9538
                     /gene="rpsQ"
                     /locus_tag="TVR04_001269"
     CDS             9275..9538
                     /gene="rpsQ"
                     /locus_tag="TVR04_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1269961.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9563..9931
                     /gene="rplN"
                     /locus_tag="TVR04_001270"
     CDS             9563..9931
                     /gene="rplN"
                     /locus_tag="TVR04_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1269962.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            10015..10320
                     /gene="rplX"
                     /locus_tag="TVR04_001271"
     CDS             10015..10320
                     /gene="rplX"
                     /locus_tag="TVR04_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1269963.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            10344..10886
                     /gene="rplE"
                     /locus_tag="TVR04_001272"
     CDS             10344..10886
                     /gene="rplE"
                     /locus_tag="TVR04_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1269964.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10902..11087
                     /locus_tag="TVR04_001273"
     CDS             10902..11087
                     /locus_tag="TVR04_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1269965.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            11459..11857
                     /gene="rpsH"
                     /locus_tag="TVR04_001274"
     CDS             11459..11857
                     /gene="rpsH"
                     /locus_tag="TVR04_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1269966.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            12180..12716
                     /gene="rplF"
                     /locus_tag="TVR04_001275"
     CDS             12180..12716
                     /gene="rplF"
                     /locus_tag="TVR04_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1269967.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12820..13176
                     /gene="rplR"
                     /locus_tag="TVR04_001276"
     CDS             12820..13176
                     /gene="rplR"
                     /locus_tag="TVR04_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1269968.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            13195..13689
                     /gene="rpsE"
                     /locus_tag="TVR04_001277"
     CDS             13195..13689
                     /gene="rpsE"
                     /locus_tag="TVR04_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1269969.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13704..13886
                     /gene="rpmD"
                     /locus_tag="TVR04_001278"
     CDS             13704..13886
                     /gene="rpmD"
                     /locus_tag="TVR04_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1269970.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            14089..14529
                     /gene="rplO"
                     /locus_tag="TVR04_001279"
     CDS             14089..14529
                     /gene="rplO"
                     /locus_tag="TVR04_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1269971.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14546..15850
                     /gene="secY"
                     /locus_tag="TVR04_001280"
     CDS             14546..15850
                     /gene="secY"
                     /locus_tag="TVR04_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1269972.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATVREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            16002..16643
                     /locus_tag="TVR04_001281"
     CDS             16002..16643
                     /locus_tag="TVR04_001281"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1269973.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVSDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16761..16979
                     /gene="infA"
                     /locus_tag="TVR04_001282"
     CDS             16761..16979
                     /gene="infA"
                     /locus_tag="TVR04_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1269974.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            17005..17121
                     /gene="rpmJ"
                     /locus_tag="TVR04_001283"
     CDS             17005..17121
                     /gene="rpmJ"
                     /locus_tag="TVR04_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1269975.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            17139..17504
                     /gene="rpsM"
                     /locus_tag="TVR04_001284"
     CDS             17139..17504
                     /gene="rpsM"
                     /locus_tag="TVR04_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1269976.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17522..17905
                     /gene="rpsK"
                     /locus_tag="TVR04_001285"
     CDS             17522..17905
                     /gene="rpsK"
                     /locus_tag="TVR04_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1269977.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17952..18890
                     /locus_tag="TVR04_001286"
     CDS             17952..18890
                     /locus_tag="TVR04_001286"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1269978.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18905..19291
                     /gene="rplQ"
                     /locus_tag="TVR04_001287"
     CDS             18905..19291
                     /gene="rplQ"
                     /locus_tag="TVR04_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1269979.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASESYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19502..19733)
                     /locus_tag="TVR04_001288"
                     /pseudo
     CDS             complement(19502..19733)
                     /locus_tag="TVR04_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20589..22156
                     /locus_tag="TVR04_001289"
                     /pseudo
     CDS             20589..22156
                     /locus_tag="TVR04_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622116.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22146..23018
                     /locus_tag="TVR04_001290"
     CDS             22146..23018
                     /locus_tag="TVR04_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269980.1"
                     /translation="MTVKDRLFSGTFEQSKKIVSKSILTEEGAAIGLMSSMTLRKKCL
                     IPFLDIIFLGLIFAVGVALPVFILNDTSSILSESTRELIYFIGQFTSPITQILIIIHF
                     VLVMLNLFPKPNYAYQLLYGNIIVLLLVVLASFSFVPFSLGLTIAAFGWIGFLPQLLL
                     CLYLWKVCVIDKCQQLRTAIYQESTIAPDWGSKLVSFIKSYGGILLGLSVLNRWTFNL
                     GELVKESPGLLSFLYGWIFLFFMFLMLFALGQALKNTIIAYYFFRYQKEYRKYFNISD
                     EQWYGKWSSKILSK"
     gene            23039..23332
                     /locus_tag="TVR04_001291"
     CDS             23039..23332
                     /locus_tag="TVR04_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1269981.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         7270 a         4218 c         5205 g         6838 t
ORIGIN      
        1 aatatttaaa ttaaacaata gtcaagtcac ctttcactaa gaaaaatcac ttgattattg
       61 cttagttttt tctaatggag gatttttagt ttagaagctt tgagtttaga cctcaaaact
      121 tagatatgga attcgaaagg cagtcactgc tgtcaacatt actttgggaa agttcctata
      181 agagactttt cattagactg aagtagcttc aatagctcta aaactaccta gactcaagta
      241 acaacaagtc cttagaattg attttctaag ggctttttac atacctaaag taattgattt
      301 catatgacaa aatcagatga ttatccattt tattaaaaaa aaaaaaacga aactgcggag
      361 acaaactaat gagtagctat ttctcactat cagctggcgt gctaaacttt tcttagaaag
      421 cgttagcagt aactaactgc catgccaaaa aattatctat caaggagagt aacaatgaaa
      481 cgactaaaaa cgttatgctt tttagcaact gctataaccc taactttggc tcctatcagc
      541 acaagccaga cacaaccaca gaccgtatat gctagtgcgg ttgttataaa agactataat
      601 aatgggtata gatattttga tgaaaataat ggacagacta tgcgtgctac aagttttgaa
      661 ggtcgtcgtc gttcatggcg agattccatt ttagatttgc ttgaacgtgt atggaataca
      721 gtggttaaat ggttgtttta aagctcaaaa tctaaagtcc ttagaattga ttttctaagg
      781 gcttttttgc tgcctcaagg taaagacatg ttcagtaaca aattgactgg ctaggccagt
      841 cctttattta tgctgatggc ttgaggctgc tgggttatta gcacagaaaa tggctgtctc
      901 aaaatcctag aaggcttatg attggaatat gatataataa tcaaaagaaa tgatgaggtg
      961 atgtgaagca atgccaatga tgtatcaatc aacaagaaat gcagctaata aggtaacagc
     1021 tagtcaagcg attttaagtg gcctagcaga cgatggtggc ttgtttactc ctacaagcat
     1081 gccagtgctg gatctagatt ttgaggagct aaagaccaag tcctatcaag aggttgccaa
     1141 gcttatttta tcagcctttt ttgatgatta tactgaagca gaattagatg cttgtatctc
     1201 ttctgcctat gatgataagt ttgatacagc agtgatagca cctctagcta cgttaaagga
     1261 ttatcataat ttggagctat ttcatggctc aaccatcgca tttaaggaca tggctctatc
     1321 tattttgcct tatctcttga caactgctgc taaaaagcaa ggtgtggggc gaaaaattgc
     1381 gattttaacc gctacctcag gtgatactgg taaggcagcg atggcaggct ttgctgatgt
     1441 tccgggaacg gatattattg tcttttatcc taagtcaggc gttagcagga ttcaggagct
     1501 gcagatgatc acacaggcca gtcacaatac ccatgttgtg gcgattgaag gtaattttga
     1561 tgatgctcaa acggaggtca agcgcttgtt taatgatcct gatttgcgtg agcggctagc
     1621 agctcgacag atacagctat cttcggccaa ttcgatgaat attggtcgtt tgattcctca
     1681 ggttgtctat tatatttatg cttatgccca attggtaagg catcagcgac ttgcagctgg
     1741 agaggtgatt aacatagtag tgccgacagg aaattttggc aatctactgg cggcttacta
     1801 cgctaaagaa attggacttc ctgtggctaa attcatctgt gcttccaatg aaaacaatgt
     1861 cctgacagat ttctttgcta gtggcaggta tgacaaaaaa cgtcccttta aggtaaccac
     1921 tagtccatca atggatattt tggtgtcttc aaatttagag cgcttggttt ttcatttact
     1981 aggcaatgat gcccaaaaga cagcatcatt aatgaagagc ttggcagaaa caggtcagta
     2041 tcagctagct gatgcagatc agtctatcct tgatttattt gcagcaggct ttgcaacaga
     2101 gcaagagact gctaaagaga tcaaaacgat atttgagtct gatcattatg tgcttgaccc
     2161 acatacagct gtagcttcag ctgtttatcg tgcttatcgg gagcaatcag gtgactctag
     2221 accgactatt gttgcgtcaa ctgctagtcc ttataagttt ccgcgggtag ttgtggaagc
     2281 tattagtggt cagcaggttg ccagtgattt tgaggcgctt gagcagttgg ctgatatatc
     2341 aggtgtagtc gtgccacaag ctgtcaatgg cttacaggag gcgcccattc gtcatagcct
     2401 tttagtgaca gtagcagata tgcagcaggc agtggaggct tatcttggag tataggaggc
     2461 ataaaggagc tccctttcaa ttgatatgaa tataatgact cacaatagaa aaaagatact
     2521 gtccttagcc cttccatcaa tggcagaaaa tatattgcaa atgctgatgg gaataataga
     2581 caattatttg gctgctcaaa ttggacttac ggcagtttcg ggcattgcga ttgctaataa
     2641 tattctgacg atttatcagg ctctttttat cgcattgggt gctgcagtct ccagcctcat
     2701 tgctagaagc gtaggagagc aaaaccattc taaaggaatc gactacatgg caaatgctat
     2761 cttagtaacg ggggctctat cagttcttct aggcttgatg tccgtagtgg gacataaaag
     2821 catattagcc tttctgggag cagctagtct ggtagctaga cttggtgggc agtatttagc
     2881 cattgtcggt ggaatgattc ttagtcttgg tcttttaacg agcttaggtg cgattattcg
     2941 tgctaagggt cagcctagca ttccaatgaa ggtcagcctt ttaactaatc tgctaaacgc
     3001 tgtattttca gccctttctc tttacgtatg gggatttgga gtaataggga ttgcttggtc
     3061 aaccgttgtg tcgcgtctta ttggagttgt tattctatgt cactttcttc ctattaaaga
     3121 aattattaaa cgttttgcta atcccttaga taaagagatc tttagcctct ctcttccagc
     3181 ggctggtgag cggctcatga tgcgagctgg tgatgtgctg attgttacta ttattgttag
     3241 atttggaaca gaggccttgg caggcaatgc gattggagaa accttaactc aatttaatta
     3301 tatgccggga cttgctatgt caactacgac cgtcatttta gttgccaatc agctgggcag
     3361 tggcaaaggg gctacaatag cgaagaccgt aaaagaaacc tttttgttaa ccactctgat
     3421 gatgcttgtt gtgggactga ttacctattt gttggggcct ggtctgctcc cattatttac
     3481 agcagatgtc aaggcccagc aggctggtat ggttgtcttg accttttctc ttttgggtgt
     3541 accagcaaca gcagggacct tggtttacac agcagcctgg cagggtatcg gacaagccaa
     3601 gctgcctttt tatgcgacaa cggttggtat gtggctggtt cggatttctt tgggctactt
     3661 tattggagtg accctagatt atggattaat aggtgtttgg cttgcgacta ttttggacaa
     3721 tgccaccaga tggctcattc ttgcggtagc ttttaagaag cagcaaaagc tgctttcttc
     3781 ggattgtcat agctaagctt tgtacctaga tctcaagact tccaagtaac ggcttccttt
     3841 tgggagtcag tcttgtcatc acaacgcaaa gtatgtctta ggctttgttg gttaatagct
     3901 tctcctatct acgggagatc aaagaggatt gctggaacag ctgagacttg tctgcaatct
     3961 tgcttgccct ttcttagggc aagttttttt tgaaaaattc cctgaaaggc ttgcaatgcc
     4021 ttattaattc tgctattata ttatggtgct gtaaaaatac agctttagct atgatacgag
     4081 aggttgcgac acgctcggtt gcattgccac gtgacaggtg tcggttttct cgaggagcta
     4141 gcctattatc gtaaatagac gagaggagaa aagatggcaa acaaaaaaat ccgtatccgc
     4201 ttgaaagcgt acgaacaccg tacacttgat acagcggcag aaaaaatcgt tgaaactgca
     4261 actcgtacag gtgcaacagt agctggacca gttccacttc caactgaacg cagtctttac
     4321 accattattc gtgcgactca caagtataaa gattctcgcg aacaatttga aatgcgtaca
     4381 cacaaacgtc ttattgatat tgtgaaccca acgcaaaaga ctgttgatgc acttatgaaa
     4441 ttggaccttc caagtggtgt caacgtagaa atcaagcttt aattgtttga aacatgagcg
     4501 aggaatgagt tcgtatctaa ttgaacacag gctaagctct gtgtgaaaaa gagacacagc
     4561 cgttctaatt ttaattagat tacggatgtg gctacctgta ggtgtaaatc ttcctagaaa
     4621 cagaagtttc ttcgtcagat ttcctatttt cactgtgagg ttgacgcctt aagtatcttg
     4681 ctttgagcat aaaaaacgct cgtaaaaaac ttttttgagc atgaaaaacg ctcactaaaa
     4741 actttttgaa atattattaa gaaaaggaat tattttctca tgacaaaagg aatcttaggg
     4801 aaaaaagtgg gaatgactca aatcttcact gaatctggtg aatttatccc tgttactgtc
     4861 atcgaagcaa ctccaaacgt tgtgcttcaa gttaaaactg ttgaaacaga cggttacgaa
     4921 gcagttcaag ttggctttga cgacaaacgt gaggtattga gcaacaaacc tgccaaaggc
     4981 catgtagcaa aagctaacac agctcctaag cgcttcattc gtgaattcaa aaacattgaa
     5041 ggcttagaag taggtgcaga aatcactgtg gatatcttcg cagctgggga tgttgttgat
     5101 gtaactggta cttcaaaagg taaaggcttc caaggtgtta tcaaacgcca tggtcaatca
     5161 cgtggtccga tggcccatgg ttctcgttac catcgtcgtc caggttctat gggacctgtt
     5221 gcaccaaacc gcgttttcaa aaacaaacat ttggcaggac gcatgggtgg caatcgtgta
     5281 actattcaaa atcttgaaat tgtacaagtt atcccagaaa agaacgttat tcttattaaa
     5341 ggtaacgtac caggtgctaa gaaatctctt atcaccatca aatcagcagt taaagctgct
     5401 aaataataag aaaggagaaa acagttaaaa atggcaaacg taaaactatt tgaccaaact
     5461 ggtaaagaag ttagcacagt tgaattaaat gatgctatct ttggtatcga accaaacgaa
     5521 tcagttgttt ttgatgttgt aatcagccaa cgtgctagcc ttcgccaagg tactcatgcg
     5581 gttaaaaacc gttcagcagt atcaggtggt ggacgtaaac cttggcgtca aaaaggaact
     5641 ggacgtgctc gtcaaggttc tatccgctca ccacaatggc gtggtggtgg tgttgtcttt
     5701 ggaccaactc cacgttcata tggatacaaa cttccacaaa aagttcgtcg ccttgctttg
     5761 aaatcagttt actcagcaaa agttgctgaa gataaatttg tagctgtaga aagcctttca
     5821 tttgcagcac caaaaacagc tgaatttgca aaggtgcttt cagctcttag cattgataca
     5881 aaagtacttg ttcttgttga agaaggaaat gaatttgcag cactttctgc acgtaacctt
     5941 ccaaacgtag ctgtggcaac agcagcgact gcaagtgttc ttgatatcgt aaacgcagac
     6001 aaacttcttg taacgaaaga agcaatctct acaattgagg aggttcttgc ataatgaatt
     6061 tgtacgacgt aatcaaaaaa ccagttatta ctgaaaaatc aatgtatgcc cttgaagaag
     6121 gtaaatacac atttgaagtt gacacacgtg cgcacaaact gttaatcaag caagctgttg
     6181 aagctgcatt tgacggagtt aaggttgcaa gcgtcaatac tgttaacgtt aaaccaaagg
     6241 ctaagcgtgt tggtcgttac acaggtttta cttcaaaaac taaaaaggct atcatcactc
     6301 ttacagctga ttctaaagca atcgagttgt tcgcagctga agctgaataa tctaaggagg
     6361 aaataacgtg ggtattaaag tttataaacc aacgacaaat ggccgtcgta acatgacttc
     6421 tttggatttc gctgaaatca caacaagcac acctgagaaa tcattgcttg tttctcttaa
     6481 aaacaaagct ggtcgtaaca acaatggtcg cattacagtt cgtcaccaag gtggtggaca
     6541 caaacgccat taccgtttga ttgacttcaa gcgtaacaaa gatggtgttg aagcagttgt
     6601 taaaacaatc gaatacgatc caaaccgtac tgcaaacatt gcacttgtac attacactga
     6661 cggagttaag gcttacatca tcgctcctaa gggtcttgaa gtaggtcaac gcattgtttc
     6721 tggaccagat gcagatatta agattggtaa tgcacttcca ttagcaaaca ttcctgttgg
     6781 tacagttgtt cacaacattg agcttaagcc tggtaagggt ggagagcttg tacgtgctgc
     6841 tggagcttct gcacaggttc ttggtcaaga aggtaaatat gttcttgttc gtcttcaatc
     6901 aggcgaagtt cgtatgattc ttggaacatg tcgtgcaact gttggtacag ttggtaacga
     6961 gcaacaatca cttgttaaca ttggtaaagc aggacgtagc cgttggaaag gtatccgccc
     7021 aacagttcgc ggttctgtaa tgaaccctaa cgatcaccca catggtggtg gtgaaggtaa
     7081 agcaccagtt ggacgtaagg cgccatctac tccttggggt aaaccagcgc ttggtcttaa
     7141 aacacgtaac aaaaaagcta aatctaacaa gcttattgtt cgtcgtcgta acgaaaaata
     7201 agcggcaaat ctagcataag cttattcaat cattccgcca gctcggtaga gtttgagctt
     7261 gctctcatgc tcaagccgct gtggtacatt atttaaagga gaaaactaca aaatgggacg
     7321 tagtcttaaa aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc
     7381 taatgacgaa aagaaaaaag taatcaaaac ttggtcacgt cgttcaacga ttttcccaag
     7441 tttcatcgga tatacaatcg cagtttatga tggccgcaag catgtacctg tgtacattca
     7501 agaagacatg gtaggtcaca agcttggtga atttgcacca actcgtacct acaagggtca
     7561 cgcagctgac gacaagaaaa cacgtcgtta ataggaggag gacacaatgg cagaaattac
     7621 ttcagctaaa gcaatggctc gtacagtgcg tgtttcacct cgtaaaacac gtttagtact
     7681 tgatcttatc cgtggtaaga aagttgctga tgcaatcgca atcttaaaat tcactccaaa
     7741 caaagcagct cgtgttattg agaaaactct taactcagca attgctaacg cagaaaataa
     7801 ctttggtttg gaaaaagcta acttggtggt atctgaaaca tttgcaaacg aaggaccaac
     7861 aatgaaacgt ttccgtccac gtgcaaaagg ctcagcgtca ccaatcaaca agcgtacaac
     7921 tcacgttaca gtagttgtat cagaaaaata aggaggtaaa atcgtgggtc aaaaagtaca
     7981 tccaattggt atgcgtgtcg gaatcattcg tgactgggat gcaaaatggt atgctgaaaa
     8041 agaatacgcg gattaccttc atgaagatct tgcaatccgt aaattcatta acaaagaatt
     8101 ggcagaggct tcagtttcaa caattgaaat tgagcgtgct gtaaataagg ttattgtttc
     8161 acttcacact gcaaagcctg gtatggttat cggtaaaggt ggagcaaatg tcgacgctct
     8221 tcgcgctcag cttaacaaat taactggaaa acaagtacac atcaacatca tcgaaatcaa
     8281 acagcctgat cttgatgccc accttgttgg tgaaaacatt gctcgtcagc ttgagcaacg
     8341 tgttgctttc cgtcgtgctc aaaaacaagc tattcaacgt accatgcgtg ctggagctaa
     8401 gggaatcaaa actcaggttt caggacgttt gaacggtgca gatatcgcgc gtagtgaagg
     8461 ctactcagaa ggaactgttc ctcttcacac acttcgtgca gatattgact atgcttggga
     8521 agaagcagat actacatacg gtaaactcgg tgtcaaagtt tggatttatc gtggtgaagt
     8581 tcttccagct cgcaaaaaca ctaaaggagg caaataacag atgttagtac ctaaacgtgt
     8641 taaacaccgt cgtgagtttc gtggaaaaat gcgcggtgaa gcaaaaggtg gaaaagaagt
     8701 atcattcggt gaatatggtc ttcaagctac tactagctca tggatcacta accgccagat
     8761 cgaagctgct cgtatcgcta tgactcgtta catgaagcgt ggtggtaaag tttggattaa
     8821 aatcttccct cacaaatctt atacagctaa agctatcggg gttcgtatgg gttctggtaa
     8881 gggtgcacct gaaggttggg tagcaccagt taagcgtggt aaagtaatgt ttgaggttgc
     8941 tggtgtttct gaagaaatcg ctcgtgaagc acttcgtctt gctagccaca agttaccagt
     9001 taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa gacatgaaac ttgaagaaat
     9061 caaaaagttt gttgctgagc ttcgtggctt gtctcaagaa gagcttgcta agaaagaaaa
     9121 cgaactcaaa aaagaacttt tcgaccttcg ttttcaagct gcagcaggtc aactagatca
     9181 aactgctcgt ttgaacgaag ttaaaaaaca aattgcacgt gtaaagactg tgcaatctga
     9241 aatgaaataa tagattggga aaggagtatt ctaaataatg gaacgtaatc aacgtaaaac
     9301 ccttgttgga cgtgttgtat ctgacaagat ggacaaaaca atcactgtta tagttgaaac
     9361 aaagcgtaac cacccagtct atggtaaacg tatcaactat tctaaaaaat acaaagcaca
     9421 tgacgaaaag aaccttgcta aagaaggcga tatcgttcgt atcatggaaa ctcgtccact
     9481 ttcagctaca aaacgcttcc gtcttgtaga aatcgtggaa gaagctgtta ttatctaatc
     9541 aaactaaaag gagacaattg aaatgattca acaagaaact cgcttgaaag ttgctgataa
     9601 tagcggtgct cgtgagatct tgactatcaa ggttcttggt ggttcagggc gtaagtttgc
     9661 taacatcggt gacgtcatcg ttgcatctgt aaaacaagct actcctggtg gagcagttaa
     9721 aaagggtgat gttgttaagg ctgttattgt tcgtacaaag agtggtgctc gtcgtccaga
     9781 cggttcatac atcaaatttg atgacaatgc ggctgtcatt attcgtgatg acaagactcc
     9841 tcgtgggact cgtatctttg ggcctgttgc acgtgaattg cgtgagggtg gctacatgaa
     9901 gatcgtatca cttgcaccag aagtacttta attttaatca ttaaacaaac taagtcccct
     9961 aggctagctt agggtgccca taagggcgta agaaaataat aggagaaacc cataatgttt
    10021 gtaaaaaaag gcgacaaggt tcgcgttatt gctggtaagg acaaaggtgt tgaagctgtt
    10081 gttcttaaag cacttccaaa agtaaacaaa gttattgttg aaggcgtagc catcatcaaa
    10141 aagcatcaaa aaccaaatag cgaaaatcct caaggtgcta tcgttgaaaa agaagcacca
    10201 atccatgcat caaacgttca agttcttgat aaaaatggtg ttgctggacg cgttggttac
    10261 aagtttgtag acggcaaaaa agttcgttac aacaaaaaat caggcgaagt gcttgattaa
    10321 tcacgaagga aaggagaagc ataatggcaa atcgtttaaa agaaaaatat actaacgaag
    10381 taattcctgc gttgacagag aagtttaatt acacatcagt tatggctgtg ccaaaggttg
    10441 agaaaatcgt tcttaacatg ggtgtgggtg acgctgtatc aaacgctaaa aaccttgaaa
    10501 aagctgctgc agaattggca cttatctcag gtcaaaaacc acttattact aaagctaaga
    10561 aatcaatcgc tggcttccgt cttcgtgaag gtgttgctat cggtgcgaag gtaacgcttc
    10621 gtggcgaacg catgtacgaa ttcctagaca agctagttag cgtttcactt cctcgtgttc
    10681 gtgacttcca tggtgttcca acaaaatcat ttgacggtcg tggtaactac actcttggtg
    10741 tgaaagaaca acttatcttc ccagaaatca actttgatga tgttgataaa gtacgtggtc
    10801 ttgatattgt tattgtaaca actgctaaca ctgacgaaga atcacgtgaa ttgcttaaag
    10861 gtcttggaat gccttttgca aaataatagg gggtaactaa attggctaaa aaatctatga
    10921 ttgctaaaaa caaacgtcct gcgaagtatt ctacacaagc ttatactcgt tgtgaaaaat
    10981 gtggacgtcc acattctgtt taccgcaagt ttaagctttg ccgcgtttgc ttccgcgagt
    11041 tggcttacaa aggtcaaatc ccaggtgttg ttaaagcgtc ttggtaaaat gatgatgtaa
    11101 aggaccttga aaaatctgta tgaaaatagg agactgacgc agcggtcttt ggacttcaag
    11161 gaagtctatc ttttcactag gattttagtc cgtactcaaa taacatgata cagagagctt
    11221 gacggacaag gtgaaaatag gaaatctgac gtagatgctt acattctagg aagctttgca
    11281 cctaaaggta gctacaactg taatctagct gaagctataa acggctgcat ctctttttca
    11341 cattgttcgt ggctcgggtt caaatcagct gataagctgt gctgaactat tttgccctgt
    11401 gggcatcatt aactagcaag tgcagcttgc aaactactag taagaggaga ataataaaat
    11461 ggttatgact gacccaattg cagacttttt gacacgtatt cgtaatgcta atcaagtaaa
    11521 gcatgaagtg ttagaagtac ctgcatcaaa tattaaaaaa gggattgcag aaatccttaa
    11581 gcgtgaaggc tttatcaaaa acgttgaagt tattgaagat ggcaagcaag ggatcattcg
    11641 cgtatttctt aaatacggtc aaaatggtga acgtgtcatc actaacttaa aacgtgtttc
    11701 aaaaccaggt cttcgtattt attctaagcg tgaggatgtt ccaaaggttc ttaatggact
    11761 aggaattgca attatttcaa cctcagaagg tcttttgact gacaaagaag ctcgtcaaaa
    11821 gaacgttggt ggagaagtta tcgcatacgt ttggtaaaat gatgatacaa aagccgtaac
    11881 gaacaatcta aaattagaaa actattctag tttgcttgca aacaaaatag tttgtctatt
    11941 ttagatggca gttcgttggc tgtgttcaaa tgatgaacac tatcaacata gcaaacgtaa
    12001 aagaactaat tgaacatggg ctaaagtctg tgtgaaaaag ataaactttt ctagaaacct
    12061 tggtttcata gtaaagtttc ctattttcac tttgcctttt acgccctaag tattttagtt
    12121 taccccgtga aaactcgtcg cgtaagcggc ctgataattt aacaggagaa aaaattaata
    12181 tgtcacgtat tggtaataag gttattatta tccctgcagg cgttgaaatc attaacaatg
    12241 acaatgttgt tactgtaaaa gggcctaaag gagaactcac tcgtgagttt aacaaaaata
    12301 ttgaaatcaa agtcgaagga aacgaaatga ctcttgtacg tcctgacgac tcaaaagaaa
    12361 tgaaaacaat tcatggtaca actcgtgcaa acttgaataa catggttgtt ggagtttcag
    12421 aaggtttcaa aaaagagctt gaaatgaagg gtgtcggtta tcgtgcacag cttcaaggct
    12481 caaagcttgt tctttcagta ggtaaatctc accaagatga ggtggaagct ccagaaggga
    12541 ttacatttac tgtagctaac ccaacatcaa tttcagttga aggtatcaac aaagaagttg
    12601 ttggtcaaac tgctgcttac attcgcagcc tacgttcacc agagccttac aaaggtaaag
    12661 gtattcgtta cgttggtgag tatgtacgcc ttaaagaagg taagacaggt aaataatgtg
    12721 cttagtggac tatggcctag gcttgcttat gtcatgctcc atgagttcaa ttaatcattt
    12781 gtcaaagaga caaacttaaa aaattaagag gtgaaaattg tgatttcgaa accagataaa
    12841 aacaaaatcc gccaaaaacg ccatcgtcgc gttcgcggta aactctctgg aactgctgat
    12901 cgcccacgtt tgaacgtatt ccgttctaat acaggcatct acgctcaagt tattgatgac
    12961 gtagcgggtg taacgctcgc aagtgcatca actcttgata aagaagtttc taaaggaaca
    13021 aaaactgaac aagccgttgt agtcggcaaa cttgttgctg aacgtgcggt ggctaaaggt
    13081 atttctgaag tggtgtttga ccgcggtgga tatctctatc atggacgtgt taaagctttg
    13141 gctgatgcag ctcgtgaaaa cggattgaaa ttctaatagg gaggacacaa aataatggca
    13201 tttaaagata atgcagttga acttgaagaa cgcgttgttg ctattaaccg cgttacaaaa
    13261 gttgttaaag gtggacgtcg tcttcgcttt gcagctcttg tagttgttgg tgatggaaac
    13321 ggacatgttg gattcggtac tggtaaagct caggaagtac cagaagctat tcgcaaggca
    13381 gttgaagctg ctaaaaagag catgattgaa gtgccaatgg ttggtacaac aattcctcac
    13441 gaggtttaca ctaactttgg tggagctaaa gtattgttga agccagctgt agaaggttct
    13501 ggagttgctg ctggtggtgc ggtacgtgcc gtcatcgagt tagcaggtat tgctgatatt
    13561 acttcaaaat ctcttggttc aaacactcca atcaacatcg ttcgtgcaac tgttgaagga
    13621 ttaaaacagc ttaaacgtgc agaagaagtt gccgcacttc gtggcatttc agtttctgac
    13681 ttagcttaag aaaggggatc atcatggctc aaattaaaat tactttgact aagtctccaa
    13741 tcggacgtaa gccagaacaa cgtaaaacgg ttgttgccct tggacttggt aaattaaact
    13801 cttcagttat caaagaagat aatgctgcta ttcgtggtat ggtgacagca atttctcact
    13861 tggtgacagt tgaagatgtc aaataaaaag ttagctagaa atctctgatt tcttgcatta
    13921 gcatgcagaa ccggcttttg tgagttattc ctttgaatga caagcagtgg tcggttggtg
    13981 catataggca tcaggctatg acatagcttg atcatgtata ggcgagtttc tatggagagt
    14041 cctttccctt catagaggcg ctagcatttt acaaaaaaag gagaaaaaat gaaacttcat
    14101 gaattgaagc ctgccaaagg ttctcgtaaa gtccgcaatc gtgttggacg tggtacttca
    14161 tcaggcaatg gtaaaacatc tggtcgcggt caaaaaggtc aaaaggctcg tagtggtggc
    14221 ggcgtacgtc taggctttga aggtggacaa acacccttgt tccgtcgtat tccaaagcgt
    14281 ggatttacaa atatcaacac taaagagtat gctcttgtta accttgatca attaaacgct
    14341 tttgaagatg gtacagaagt aactccagtt gttcttaagg aagctggaat cgttcgtgct
    14401 gaaaaatcag gcgttaagat tcttggtaac ggcgaattga ctaaaaaatt gactgttaaa
    14461 gcagcgaaat tttcaaaatc tgctgaagca gccattactg ctaagggtgg ttcaatagaa
    14521 gtcatctaat gaggggatac tcattatgtt cttaaaaata ctcaaagacg cattgaagat
    14581 aaagaatgtt agaaataaaa tattttttac aatctttatt atccttatat tccgtattgg
    14641 aacacatatc actgttcctg gtgtaaatgc aaaaagctta gagcagctga gtgagcttcc
    14701 tttcctaaat atgttgaact tggtcagcgg taatgcaatg agaaactttt cagttttctc
    14761 aatgggtgtt agtccctata ttacagcctc aatcgttgtt cagctattgc agatggatat
    14821 tttgccgaag tttgttgagt ggggaaaaca aggtgaggtt ggccgtcgta agctaaacca
    14881 agcgacgcgc tatatttccc ttgtcttagc ctttgctcaa tctatcggta ttacagcggg
    14941 ttttaacacc ttatcaagtg tggccctagt caaaacacca gatgtaagaa cctatttact
    15001 gattggagct ttactgacaa caggtagtgt gattgtgacc tggcttggtg aacagattac
    15061 cgataaaggc tttggtaatg gggtgtctat gattatcttt gcaggtatca tttcctctat
    15121 tccaaatgct attgcaaccg ttcgtgagga ttattttgtc aatgtgaagt caggtgacct
    15181 acagtcatct tatatcgttg ttggtattct cattcttgca gtgcttgcta tcgtcttttt
    15241 cacaacgtat gttcagcagg cggaatataa aattccaatc caatatacaa agcttgttca
    15301 gggtgcgcct acaagctcat accttccctt aaaagtaaat ccagctggtg ttattcccgt
    15361 tatctttgcc agctcgatta caacaattcc aagtacgatt atcccgttct ttcaaaatgg
    15421 cagagatatt ccatggttga caactttgca aggaattttt aactatcaat ctccaacagg
    15481 aatgattgtt tatgccttgt taattatcct gttttcattc ttctatacct ttgttcaagt
    15541 aaatcctgag aaaacagctg aaaatctaca gaagaattcg tcctatattc caagtgttag
    15601 acctggacga gaaacagaag aatttatgtc atccttgcta aagaaattgg caactgtggg
    15661 tgctatcttc ctagcattta tatctcttgt tccaattgcg gcacaacaag ctcttaacct
    15721 atcttctagt attgcattag gtggaactag cttgctgatt ttgatttcga caggtatcga
    15781 aggtatgaag cagcttgaag gttaccttct caagagaaaa tatgtcggat ttatgaatat
    15841 tacagaatag aatatgggtt gacactgtca accttctatt ttgtttttaa atgacaataa
    15901 gatttacaga gccttggttt ctatcttctt attgccattt gaaaacaaaa acaaggaaaa
    15961 ctaaatttcc tattatcttt atgtcaaaag aggagaaaaa gatgaatctt ttaatcatgg
    16021 gcttacctgg tgccggtaag ggtacacagg ctgcaaagat tgttgaaacc tttgagctta
    16081 ttcatatttc aacaggagat atgttccgcg ctgcaatggc taatcagact gaaatgggag
    16141 ttcttgcgaa atcttatatc gataagggtg atttggtgtc agatgaggta accaatggta
    16201 tcgttaaaga acgcttagca caagctgata ttaaagaaaa gggatttctt ttagatggct
    16261 atcctcgtac cattgagcag gcacatgcct tagatgaaac cttaaaagca ttgggactta
    16321 cgttagatgg tgtgatcaac attgaggttg atcctgcgtc actcattgac aggcttagcg
    16381 gtcgtatcat caacaaaaaa acaggggaaa ccttccataa gatctttaac ccaccagtgg
    16441 gagactataa ggaagaggac ttttatcaac gtgaagatga taagcctgaa acagttaagc
    16501 gtcgcttaga tgttaatatt gcacaaggtg agcctattat caagcattat cgtcaagcag
    16561 gcattgttcg tgacattgac ggaaacaagg acatttctga ggtctttgct gacattaaaa
    16621 aggtcatcga aaacctgaaa taaattccag aaaatcgctt gcgaaagtga ttttatcgtg
    16681 atatactaga ctagtctgac ttataattgt tacctctgtg ctcagaggac atcaaatcga
    16741 aatttagggg gtacttttgc gtggcaaaag aagacgtgat tgaaattgaa ggtaaagttg
    16801 tcgaaactat gccaaatgca atgtttactg ttgaattgga aaatggacat cagattttag
    16861 caaccgtatc aggaaagatc cgcaaaaact acattcgtat tttagtgggt gatcgtgtta
    16921 ctgtagagat gagtccttac gacttgacac gtggacgtat cacataccgc tttaaatagt
    16981 cgaaataatt ggagggatta aaacatgaag gtaagaccat cggttaaacc aatttgcgaa
    17041 tactgcaagg ttattcgtcg taacggtcgt gttatggtaa tttgtccgac aaatccaaaa
    17101 cacaagcaac gtcaaggata agatagaaag gagaaaaaat ggctcgtatt gctggagttg
    17161 atattccaaa tgataagcgt gtagtaattt cacttaccta tgtgtatgga attggtcttg
    17221 caacatctaa aaaaatctta gcagcagcag gtgtctctga ggacattcgt gttaaagatt
    17281 tgacatcaga tcaagaagac gctatccgtc gcgaagtgga tacaattaaa gttgaaggtg
    17341 atcttcgtcg tgaagtaaac ctaaacatca agcgtttgat ggaaatcggt tcatatcgtg
    17401 gaattcgtca ccgtcgtgga cttcctgtac gtggacaaaa cacaaaaaac aatgctcgta
    17461 ctcgtaaagg taaagctgtt gcgattgcag gtaagaaaaa ataaaatagg aggtaaaaaa
    17521 attggctaaa ccaacacgta agcgtcgtgt gaaaaagaac atcgaatctg gtgttgcaca
    17581 tattcacgct acatttaata acactattgt tatgattaca gatgtgcacg gtaatgcttt
    17641 agcatggtca tcagccggtg ctcttggttt taaaggttct cgtaagtcaa ctccttttgc
    17701 tgctcaaatg gctgcagagg ctgctgcgaa atctgcacaa gaacatggtt taaaaactgt
    17761 tgaagttact gtaaaaggtc ctggttcagg tcgtgaatca gctattcgtg ccctagctgc
    17821 tgccggtctt gaagtgactg ccattcgtga tgtgactcct gtaccgcata atggtgctcg
    17881 tcctccaaaa cgtcgtcgtg tataatcaca gtaacaaata gtacacaagt ttcgtttcga
    17941 ggggtgaaag aatgattgag tttgaaaaac caataataac aaaaattgat gaaaataaag
    18001 attacggtag atttgtaatc gaaccacttg aacgtggata tggtacaact ctaggtaatt
    18061 cacttcgtcg tgtactcttg tcttcacttc caggtgcagc tgttacatca atcagaattg
    18121 atggagtact acacgaattt gatacaatcc caggtgtacg tgaagatgtc atgcaaatta
    18181 tccttaatgt taagggactt gctgtgaaat catacgtcga agacgaaaag attatcgagc
    18241 ttgatgtaga aggcccagca gaggtaacag ctggagatat tctcacagat agcgatatcg
    18301 aacttgttaa ccctgatcat tatcttttta ctattgctga tggttataca ttgaaggctt
    18361 caatgactgt cgctaaaaaa cgcggctatg taccagcaga gggtaataaa aaagatgatg
    18421 cacctgtggg gacgttggca gtagattcaa tctatacgcc agtaaaaaag gttaattatc
    18481 aagttgagcc tgctcgtgta ggtagtaatg acggctttga taaattgact attgaaatca
    18541 tgacaaacgg aacaattatt ccagaagatg ccttaggttt atctgctcga gttttaatcg
    18601 aacacttgaa tttgtttact gacttaacag atgttgcaaa agcaactgaa gtgatgaagg
    18661 aagctgaaaa agtaaacgat gaaaaggtac ttgatcgcac tattgaggaa cttgatttgt
    18721 ccgtacgctc atataactgc ttgaaacgtg ccggtattaa tactgtcttc gatttaacag
    18781 aaaaatctga gcctgaaatg atgaaggtcc gtaaccttgg acgtaagagt cttgaggaag
    18841 taaaggtcaa gcttgctgac ttaggtttgg gactaaaaaa cgataaataa cataggagga
    18901 taaaatggct taccgtaaac taggacgcac tagctcacaa cgtaaagcaa tgcttcgtga
    18961 cttaacgaca gatcttttga ttaacgaatc aattgtaacg acagaagcac gcgcaaagga
    19021 aatccgtaaa acagttgaaa aaatgattac tcttggtaaa cgtggtgatc ttcacgctcg
    19081 tcgccaagca gctgcatacg ttcgtaacga aatcgcatca gaaagctatg atgaagctac
    19141 tgataagtac acatcaacaa cagcacttca aaagcttttc tctgaaattg cacctcgtta
    19201 tgcagaacgc aacggtggat acactcgtat ccttaaaaca gaaccacgcc gcggagatgc
    19261 tgctccaatg gcgattattg aattagttta atttttatca attttgttga gtgttatgat
    19321 gatggagcag ttcttttaag ctgttcttag tctagctctg gtctaccgct aggacctttc
    19381 ctagcggtaa cactcatcat gttgaggata agtaacgctt gtttacgaaa ggtctctaag
    19441 ctgtaggtgc ccttcgtaag caggcgtttt gttgtgactc catgttaact gtagtggatg
    19501 actaatatct agagaggatc agcttggtgc tctcttttct gatattaaaa gcattgggaa
    19561 tcttggtttt gaagttctta aagctcctaa agccaaagtc tttcgcttga tgtctttggt
    19621 catcttgtta gtggtctccg gcttagcatt ggaataaggt agttcaaagc attagtgatg
    19681 taaaatctat actttctgaa tgtcttgaaa accgttttga aggtgtgatt gacctgtagt
    19741 gggagtagat tagatcaatg gcgtttgcct gctttgaaaa tttaggtgac aattgttttt
    19801 atatctttgt ttaaaaatgg tataatatta aaaaattaaa caaaatgtac ataaaaaagc
    19861 catataaaag aatgatatta agataatgtg atcaatagtt ttagaaaatg aatgtgtaag
    19921 gttaaggtat gcccccttga tataatgcta gttttacgaa gaggcattct gtacagacat
    19981 aatgcactct tacaaatgat acggtaattg ctcaacaagg cgcaacagcc ttggcaaatg
    20041 taatatttgc cttagctagc agcgaattag ttacgcttga tacatagaca agggtttctg
    20101 gcatacagca gcagatggtg tgcctgtctc agagagtggc tgcttggctt atcctattca
    20161 tgtcttaaaa cttacaggag gtgttatgtg gcctttggtc gatggatatt tagctaggtg
    20221 aacagctatt agctgtaaat atgaggtagg agctttagtt tgcatgatgt taaatgaatt
    20281 gaaacagact taggaaagct tggcttagca actatcacgc aagttcttaa caacgataaa
    20341 gatcgtatgg gaaaatatga tcaagcatca acggacatga gatgtgtttt atgaagaaac
    20401 cattatactt ttataagact tatttagttg tttttctttg cggacttgtt tgaggagtag
    20461 tctacatagg caataggctc aggcttacag cacttaggag acattagagc atgagaagca
    20521 ctaactggct agtgatagaa aagtaatagc acagtgtttt tataactaac aagaggagta
    20581 gacattctat gagtattgac atgtatttga gcttatctga agagcaggca cagagtgtag
    20641 aggctgtctt agctaggcga caaacagcct atcaatcctt acaggagacc ttgatccaat
    20701 tgatttctaa cagtcctgat ttatcagggc ggacctatga ttctgctaag gcttatagta
    20761 gtcaagtgct aattcctttg ttaaaggggt gtatgctttt agatgaggcg attataacag
    20821 cctgtaagag gctacctagt gggtaccgta gtcaggtaga ccaaattgat ttgaaggaga
    20881 gtgatctggt tgagcgtatt gcccagttcg atcatgtgat tggtcggtac atggatttga
    20941 ttagtattga atacggtaga gaggagccta gctattccta tatctctcat ttaagatcag
    21001 ctgagcagct ccatcgggcc gttaagcggc gtcttgagga gatattgcga aggctaaggc
    21061 attttgatac caactcagtt cacctttttt cgactattca gactttggca gcagcggtac
    21121 agataggcat gcgtcaagct aggacctcgt ggcatgcagg aagtcaggta tttgtgattt
    21181 cagaggatat ggcatgggcc gatacgatta attctaagtg gtcaaaaagt aaagggttaa
    21241 gccatcttgg tgattatgtt tacgacccag atgtgctcgc taagggagta gctattagtc
    21301 acccttggat taaaacaggt tatactatgt ctaaacattt tggtaaagct gtttcaaaag
    21361 attatacaaa agcaagcttt tgagctatgg taaggcaggt aagagagcca gtgatgactt
    21421 aaatcttgct tggcgtgata ttagaaatct tgcccgtcaa aagcattggg catggtatga
    21481 gaggttgggg cataaatgga aaaaaggaag ctttagccag ctgcttaaca cgtttcaaaa
    21541 gacgatattg aaaaagatct cggattttaa ggcttttggt aaatattcta taaaacagat
    21601 aagtacaatt gttggaaaag ttacagatcc tatcaaaagc tctattgaaa cacttggaaa
    21661 acacattaaa aattctcgtt tatttaacaa agtgagatgg attggtaagg cagccaaggc
    21721 gactggctgg acttctatgg cagtagatac tggaataact agtgtaaggg aatacaataa
    21781 gaaaaatagt agagcctatg gcagtgaggg caaggcgctt attcatgcta gtgtggctca
    21841 aatcaagagc atgggaccta tagaaggggc aattgtaggg tcagctttaa gtggtccaat
    21901 aggggcaatg ttaggtttta tcggaggaac gataaataca ttgtggggca tagcagcacc
    21961 agactctaga gataaagcct tttcttgggg acaagctaga ttggacgacg cttacgattt
    22021 gattgcccag acggatcttg gcaaagggac ataccatgct aaagaaagag tcaaaggtca
    22081 tatcggtcga gctattgtaa ggacatggga ctttgtcagt caatcatttg gtaaaggagt
    22141 gggctatgac agttaaagat cggcttttta gtgggacatt tgagcaatca aaaaagattg
    22201 tgtctaaaag catattgaca gaagaaggtg cagcaatcgg tctaatgtct tcgatgacac
    22261 taagaaaaaa atgtcttata ccttttctag atattatttt cttgggcctg atttttgcag
    22321 ttggtgtggc tcttccagtt tttattttaa atgatacatc tagtatactc tcagagagta
    22381 caagggagtt aatttatttt ataggacaat tcacatcgcc tataacacaa atcttaatta
    22441 ttattcattt tgttttagtt atgcttaatc tttttcctaa gcctaactat gcttatcaat
    22501 tattatatgg aaatataatt gttcttcttc ttgttgtttt ggctagtttt tcttttgttc
    22561 cttttagttt aggccttaca attgcagctt ttggctggat cggttttttg cctcagctat
    22621 tgctttgcct ttatttgtgg aaggtttgtg tcatagataa gtgtcaacag ctacgcacag
    22681 caatttatca agaaagcacc atagcacctg attggggcag taagctagta agctttatca
    22741 agtcctatgg tggtatctta ttaggccttt ctgttctcaa ccgctggact ttcaatctag
    22801 gagaactagt caaggaaagt cccggtttgt tgagttttct gtacggctgg atctttttat
    22861 tcttcatgtt tttgatgcta tttgcactgg gtcaagcgtt aaaaaatacc atcatagcct
    22921 attatttttt tagatatcaa aaagaatacc gcaagtattt taatataagc gatgagcagt
    22981 ggtacggtaa atggagttca aaaatattat caaaataaac gatataagga gtaatcatat
    23041 gcaaaaagaa ttattaccgt taggaagtgt tgtctatcta gagggagcaa caagcaagct
    23101 aatgattgtc ggacgtggtc ctatatttga atctaatggc caaaatgtct acagtgatta
    23161 tgttggagta atgtatccag aagggatcaa tccagaagac gcgatttttt tcaaccacga
    23221 agatattgca aaaacagtct ttgaaggctt caaggacgaa gaagaacaac gctttttaga
    23281 agtgtattct gattgggaga gtactttaga aatttccaaa ataaagctat agatgaactg
    23341 tagcagatct atttgtcagt agattgttat gattatattg aaagattatg actttctctg
    23401 gcttaaatac ttctaaagtt ccaaagttta gaaaaggctt taaaatgagt gttataatag
    23461 catttatgct cattaaataa aggtagcatt tcaatagaat cggtaaaaaa ataaaaaaac
    23521 cagcaaaatc c
//
LOCUS       DARYSY010000036        23008 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYSY010000036 DARYSY010000000
VERSION     DARYSY010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23008
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            131..970
                     /locus_tag="TVR04_001292"
     CDS             131..970
                     /locus_tag="TVR04_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1269982.1"
                     /translation="MKKQSFLTGFVFPLLFFLGLLIASYPLLSHYYYRVQQNRAVQAF
                     ETAKRQVDSNDVQQRIALAKAYNATLDPGRLNDPYTNLEKKGVAEYARMLELNEQIGY
                     VEVPRFDINLPIYAGTSEDVLQKAAGHLEGTSLPIGGESTHTVITAHTGLPQAKLFTD
                     VHQMKKGDLFFIHNLDKTLAYRVDRILVVEPDDFSPVLVTSGKDYATLLTCTPYGINS
                     HRLLVRGYRIPYQKAAQKVKQQSLWDRYRLLILFLFVSVILLSVLLMLWYHKRYRKEK
                     VSE"
     gene            963..1856
                     /locus_tag="TVR04_001293"
     CDS             963..1856
                     /locus_tag="TVR04_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1269983.1"
                     /translation="MNRQRYFGYLLMMLGLGLPLIFLTMMLISQLQETSSYHQFQVTQ
                     RTWSDLQVKWIKHHNQHQELTDQATTDPFVESRSQQEQSPFDDDIIGYVIISKLNMVQ
                     PIRIGASEGHLEKGVAQVTGTSLPVGGLGTRSVIAGHRSWYSDPRFLRIAELEEGDEI
                     LIDLGVRQLEYRVQSVEIINAMDWQQLKAKEGQDLLTLLTCNPLYPPFNERLLVNAER
                     VSSSHEETTGFSAVLQAGQKRRKDRPHRSILDMVLDSTKRLIANVPLLYWVIAGWSME
                     VYFGLCLLRKRRSINSTLSSH"
     gene            complement(2035..3300)
                     /locus_tag="TVR04_001294"
     CDS             complement(2035..3300)
                     /locus_tag="TVR04_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1269984.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     ALDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTLSITSVTALAESLVAQNNGIIAAIDQGRKERAQLESAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIDQAEHKP"
     gene            complement(3315..4172)
                     /locus_tag="TVR04_001295"
     CDS             complement(3315..4172)
                     /locus_tag="TVR04_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1269985.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QTGETNTTN"
     gene            4515..5807
                     /locus_tag="TVR04_001296"
     CDS             4515..5807
                     /locus_tag="TVR04_001296"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1269986.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(5920..6693)
                     /locus_tag="TVR04_001297"
     CDS             complement(5920..6693)
                     /locus_tag="TVR04_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1269987.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEIVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            6818..7564
                     /locus_tag="TVR04_001298"
     CDS             6818..7564
                     /locus_tag="TVR04_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1269988.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            7579..8559
                     /locus_tag="TVR04_001299"
     CDS             7579..8559
                     /locus_tag="TVR04_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1269989.1"
                     /translation="MKEERKRLLAKVAYLHYVQGKSQTAISKEMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTIKDGDKIGLSWGATLSSLIDELDPKAMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQEDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGRQ
                     TSQWRDLLTDKDYKQLADEKAVGEVCCRFFDQEGHGVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQDKAKAILAALKAKFINYLITDKATIMAVLALDQDQTAGTYLS"
     gene            8797..9117
                     /locus_tag="TVR04_001300"
     CDS             8797..9117
                     /locus_tag="TVR04_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1269990.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINLIKEIIELRKE
                     LAEN"
     gene            9142..9450
                     /locus_tag="TVR04_001301"
     CDS             9142..9450
                     /locus_tag="TVR04_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1269991.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEAICKENGIPIAVIPMADYGMLDGGKVLDLALSLIKE
                     "
     gene            9461..10765
                     /locus_tag="TVR04_001302"
     CDS             9461..10765
                     /locus_tag="TVR04_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1269992.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKEGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPQAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTLIYFPFFKVQDNIAYQNELAAEKA"
     gene            11046..13463
                     /locus_tag="TVR04_001303"
     CDS             11046..13463
                     /locus_tag="TVR04_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1269993.1"
                     /translation="MTEVKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYKK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERARAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            13478..14146
                     /locus_tag="TVR04_001304"
     CDS             13478..14146
                     /locus_tag="TVR04_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1269994.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNQAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RQTI"
     gene            14271..15362
                     /locus_tag="TVR04_001305"
     CDS             14271..15362
                     /locus_tag="TVR04_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1269995.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHDLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVAAALVAVDAYVCSRT"
     gene            16255..17307
                     /locus_tag="TVR04_001306"
     CDS             16255..17307
                     /locus_tag="TVR04_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1269996.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYLDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFSEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEQWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYELLD
                     SSRYSDNAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            17336..17914
                     /locus_tag="TVR04_001307"
     CDS             17336..17914
                     /locus_tag="TVR04_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1269997.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSLYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WADFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            18105..19049
                     /locus_tag="TVR04_001308"
     CDS             18105..19049
                     /locus_tag="TVR04_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269998.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPMG
                     PAGPQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDTGAPGP
                     KGEKGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQGQR
                     GEKGEQKPKGDQGKDTKPSAPKAPEKAPAPKAPKASEQSASPKVPALKSAPSKSASPA
                     GQKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(19276..20622)
                     /locus_tag="TVR04_001309"
     CDS             complement(19276..20622)
                     /locus_tag="TVR04_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1269999.1"
                     /translation="MKKNQITRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGHSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDSEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     VVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYELFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(21259..21363)
                     /locus_tag="TVR04_001310"
     CDS             complement(21259..21363)
                     /locus_tag="TVR04_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1270000.1"
                     /translation="MTAFEVVQTLLGFSSFTIALISLCYKIFKNDNKK"
     gene            complement(21662..21766)
                     /locus_tag="TVR04_001311"
     CDS             complement(21662..21766)
                     /locus_tag="TVR04_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1270001.1"
                     /translation="MTAFEVVQTLLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(22146..22661)
                     /locus_tag="TVR04_001312"
     CDS             complement(22146..22661)
                     /locus_tag="TVR04_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL1270002.1"
                     /translation="MKVVIIGHSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLN
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNKLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHNS"
BASE COUNT         6483 a         4633 c         5162 g         6730 t
ORIGIN      
        1 aataagtggc atctttattt cattatagga ttattgttac tgctagtgct cttaatttat
       61 ttttggtatc gttgcatcaa aaaaaggatc attaggaaag gagcgattct tggtaaaaaa
      121 taattcagct attaaaaaac agtcttttct taccggtttt gtctttcctt tactgttttt
      181 ccttggttta ctcattgctt cctacccttt attatcacat tattattatc gtgttcagca
      241 aaatcgagcg gtgcaggctt ttgagacagc caagcgtcag gttgactcca atgatgttca
      301 acagcgtatt gccttagcaa aggcttataa cgctaccttg gatcctggtc gcctcaatga
      361 cccttataca aatcttgaga aaaaaggtgt tgcagagtat gcgcgaatgc tagaacttaa
      421 tgaacaaatt ggttatgttg aggttcctcg atttgatatt aatctaccga tctatgcagg
      481 tacgagtgag gacgttttac aaaaagcagc agggcatttg gaagggacct cccttcctat
      541 tggaggagag agtacacata ctgttattac ggcgcataca ggattacctc aagctaaatt
      601 atttacagat gtccatcaaa tgaaaaaagg agatttgttt tttattcaca atctggataa
      661 aactttagct tatcgggtgg atcggattct ggttgtagag ccagatgatt tttctccggt
      721 gctggtaaca agtggtaaag actatgcgac gcttttgact tgtactccct atgggattaa
      781 tagccatcgg ttgctagtaa gggggtatcg catcccttat caaaaggcag cccaaaaggt
      841 aaagcaacaa agtctctggg ataggtaccg ccttttgatt ttatttttat tcgtttctgt
      901 tatactatta tcagtgcttt tgatgctttg gtaccacaag cgctacagaa aggaaaaagt
      961 gagtgaatag gcaaagatat tttggctacc ttttgatgat gcttggtttg ggtctgcctc
     1021 tgatttttct aacgatgatg cttattagcc agctacaaga gacctcttct tatcatcagt
     1081 ttcaagtaac tcagaggaca tggagtgacc tacaagtaaa gtggattaag catcataatc
     1141 aacatcaaga gctgactgat caagccacaa ctgatccttt tgttgaatca aggtcacagc
     1201 aggagcaaag tccttttgac gatgatatta ttggctatgt gatcatttca aagcttaata
     1261 tggtacagcc gattcgtatt ggtgctagtg aaggtcatct tgaaaagggg gtggcacagg
     1321 taacggggac tagtttacca gttggtggct tgggaacacg atcagttatt gcaggtcatc
     1381 gtagctggta tagtgatcca cgctttctta gaatagcaga gctagaggaa ggagatgaga
     1441 ttttaattga tttaggtgtt cgccaattgg agtacagggt acagtccgtc gagatcatca
     1501 atgcgatgga ttggcagcag ctgaaggcta aagaagggca agatctctta accctcttga
     1561 cctgtaatcc tctttatcct ccttttaatg aacgtttatt ggttaacgct gagcgagtat
     1621 cctcttccca tgaagaaaca acaggcttct cggcagtcct gcaagcaggt caaaaaagaa
     1681 gaaaagacag gccacaccgt tctatcctag atatggttct tgattccact aaaagactca
     1741 ttgccaatgt tcctctgctg tattgggtga tagctggttg gagtatggag gtttattttg
     1801 gcctttgctt gcttcgaaag cgaagatcaa ttaacagtac cctctctagc cactaatttt
     1861 agctataagc ccttgctaag aatacctagt agctaagtca tacaaagaaa ataagtgact
     1921 attacaaata ccctttgtca gtagtggtgt ctgacaaagg gtattttttg ttattaccaa
     1981 tcaaaaagcc acaggcagag tgtctgtggc aggtctatct taccaagaga ggctttaagg
     2041 cttgtgttct gcctgatcga ttgtctcttg tttttccttg ccctcattga ggagagcttg
     2101 aatgatgctt tggtcgcgca gcttgacaga gtcattaatg gtttctgctg atttgataat
     2161 cgctgactcc agctgagccc gttccttgcg tccttggtca atagcagcaa taatgccgtt
     2221 attttgagca actagacttt ctgctagagc agtcactgag gtgatagaaa gggttgggct
     2281 ttgagctgtc cgctcaagat ttggaattgc ttctttactt gtctcagcta gcatttgtag
     2341 ggcagcgttg ttggcattga caatggcgtc tgcggtcatt ccagacttga cagactgctg
     2401 catgatcccc agctgagcaa tagataattt catggttgga atggtgttgc ggcgtagcat
     2461 gcccagcttt tgccgcatgt cagaggacac cttgacgagg ttacgcattt gcggtgttgt
     2521 tgcccaagcc acatagagcc gactaaggta ttcggtatgc tgctgctcaa gggtattgag
     2581 aacctctgtt gtcctagcca ataggtcaga ttgcacctga tactctggtg ttgtcgtgtc
     2641 aagtgctgca agctcctgct gcaaagtaag ggcgcggcta gaggtttcct tttggctagc
     2701 ttcaagaaag gcaatcaccc caaccagatt ttcaatcgac ttggtattat cctcgatcaa
     2761 gagctctgca gccacaatat tacgagcaag cgtgtcttct tgcttgacaa cagctgctgc
     2821 catgccgtcc attttttgct caatggtctg agaatcaaag taaaattcct gaagcgtgtt
     2881 cttgctttgt ttgaatagct tttgcaaaag cgttggcttt ttttcaagct cagctgcagt
     2941 cgcttcctta tatttggcaa taaaaccatt gagctcacga ttggtgtttt tgaggagctc
     3001 atcaacctgc ggaatctgta atttcttttg ctcagctaga atatgattaa cagtagcatt
     3061 aaccccttca acggctgctt gaccaaaatc aagtagggca ttttgatcct ccataaaggt
     3121 atccacaagg gctggtgcct ttgcagtaat ggcctgctgc tgctcaggac tcagcttttc
     3181 ataaaaagaa atttgtccag tagtattggt cggtagctta gtgataatat cggtggtttt
     3241 atctgtttta gtgatagcat tattagcaat ctggtcaata tcaaagtgaa attctgccat
     3301 aaatagctcc tttatcagtt ggtagtgtta gtctcaccgg tctgggcaga gcccttcatc
     3361 atacgtagac taacatcaaa atccttaagc tcactctcgt ttagcttcct tagggtctca
     3421 tcaaggtcca gatcaaactg ttggattgcc tcaagagcct gctgcaagcg ctcatcagca
     3481 ttgtaataat ttttaggtgt ttctttgatt tttaggtagc cctgcaaaat gtcttgaaac
     3541 ctgcgcatat tagcctcatg gagtgctaag agttcctcgt gattatcagc tcccttgatt
     3601 ttttctaaaa tcgagtggtg gtcagcctgg atattgtcat aatagtgacg tagctcgggc
     3661 gccttataaa tggggtcagc tgcctgctcc tttaggcttt cagccttcag atttgctgcg
     3721 atttgaatct tttcgagctg tagctgcaca tcgctttcca cgtcattagc ctttttggtc
     3781 acacgacggt aaatgctaat atccatgtgt tccttgaggt gaccgctttc ttttttgatt
     3841 tcactcaatt gcggcagtag ctgcttggct aaaatggcat actgtgtaaa atcttcctta
     3901 gccagataat gatcaaggag cttaaccttt cggtcggcaa gctgaatagt tgcctttaaa
     3961 tcctccaagc gtttctcaag tgttgccgtt tttaagcgag cctgacggtt cgaatagcga
     4021 taagcagcat aaccaacacc cagcgctgca aaaatcagaa cagctttgtc aatattttct
     4081 acaactccta ctaaaatcgc gaagcctatc agccagccaa accagctaaa gccctttctt
     4141 cgtcgagata cttggtaata ttttcgtgac atgtaaaact tcctttgtac tttttatcac
     4201 agtaaacaat cagttagttc tattttacct taaaaatgtg atttcttaaa ggaaagatta
     4261 gcagatttag cattattttc cttcaaagac tggtcttgct tgctttttag tgaaatgttc
     4321 gctttctgcc tgttttcaga aaaaagcatt tgccatttga tattttttct taataatgcc
     4381 aaggaaagat agcagaaaac cacatttttt gctataatga ggtgtaacag acacttgcag
     4441 gtgagagtcc tgccacattt atcaagaaag gtgggggctc tctttctttg ttgagatgag
     4501 cctatatcga agatatgaca tcagtagtag tagttggtac ccagtggggt gacgaaggta
     4561 agggtaagat cactgacttt ttatcctcag atgcagaagt gattgcacgt taccaaggtg
     4621 gtgacaatgc aggacatacc attgttattg ataacaagaa attcaagctg cacctgattc
     4681 catcaggtat tttcttccca gaaaagattt ctgtgattgg aaatggtgtg gttgtcaatc
     4741 caaaatcctt ggttaaggag cttgcttacc tgcatgagga gggcgtgacc acagacaatt
     4801 tgcgcatttc tgatcgtgct catgtcattt tgccatacca tatcaagctt gaccagcttc
     4861 aagaggaagc aaagggtgac aataaaatcg gtaccaccat caagggcatc ggtccagcct
     4921 atatggataa ggcagcacgt gttggtatcc gtattgcaga ccttttagac agggatattt
     4981 ttgctgagcg cttaaagacg aatctggctg agaaaaatcg tctttttgag aaaatgtatg
     5041 acagcgcacc gattgcattt gacgagattt ttgaagaata ctatgcttat ggtcaagaga
     5101 tcaaaaaata tgtgacagac acatctgtta ttttgaacga cgctcttgat gcgggcaagc
     5161 gtgtcctttt tgagggagct caaggggtta tgcttgatat tgatcaggga acctatccat
     5221 ttgtcacctc atctaatcca gttgctggcg gtgtgaccat tggctcaggc gtcggaccaa
     5281 gcaaaatcaa caaggttgtt ggtgtgtgca aggcctatac tagtcgcgtt ggtgatggac
     5341 cattccctac cgaattattt gacgaggttg gcgagcgtat tcgtgagatt ggtcatgagt
     5401 atggaacaac cactggtcgt ccacgtcgcg ttggctggtt tgattctgtt gtgatgcgtc
     5461 atagtcgtcg tgtgtcaggc attaccaatc tatcactcaa ctctattgat gtgctatcag
     5521 gccttgagac cgtaaaaatc tgtgtcgctt atgaccttga tggcaagcgc attgatcatt
     5581 acccagcaag ccttgagcag ctaaaacgct gcaaaccgat ttacgaagag cttccaggct
     5641 ggtcagagga tattaccggt gttcgcagcc ttgaggatct cccagaaaat gctcgcaact
     5701 atgttcgtcg tgttggcgaa ttggttggtg ttcgtatctc gaccttctca gtaggtccag
     5761 gacgtgagca aaccaatatc cttgagtctg tttgggcaac tatctaagct ggctattgtg
     5821 atgacacagg cttagctgaa tattaacgaa aacacgagca atcctaagga aggctatccc
     5881 aaggagctgc tcgtgttttt tggtataagg cttttaagtt taaaaatagc aatggatatg
     5941 atgattgaga aagatttgct gataatccac cagatcctct gggtgataag cgacagcatc
     6001 agccatgtca taacttctgc ctagcaattt gtatttgttt tcaccaaatt ggtggaaggg
     6061 aagtagctgc acctgattaa tgtttagctg attgaaaagc tcagaaaatg ccttggcgtc
     6121 ctccaaagaa tcgttgaaat tcggaatgac agggatacgc aggacgattt ctttgcccat
     6181 ctcaaaggcg tagtggatat ttttaatgat caggtcattt cgcactccgg tgaccttggt
     6241 gtgctttagg cgattatagt gcttcaaatc ggtataaata aagtctacat agttgatcag
     6301 ctcagcaaat tgctcgtgct tagcaaaggc tgtcgtttcg atagctgtgt gtagcccttc
     6361 tgccttagca gcctttagaa gcgctaaggc aaagtcaaat tgagcaaaga tttcaccgcc
     6421 agacaaggtc ataccaccgc cagattcctc gtaaaaatca agatccttta aaacctcagc
     6481 aataatctct tcaaccgtct tttcctgacc aacgatttct gtctttagtc catctgtgct
     6541 tagcattttt tcgggtaacg ttttttgtga ttcgggattg gcacaccagg gacagcgtaa
     6601 gggacacccc ttgagaaata cagttgtgcg aatgcctggt ccatcgtgta tgctaaaatg
     6661 ctggatatta aatacaatgc cttttgtcgt catagcgaga cttcctttcg ttctaggact
     6721 atcataacag ataaacgtaa ataaatcaat tacgaacgaa agttattttt gcttttcatt
     6781 taccgccata attgttacaa tggaaaggag gtaaattatg aatcgtttag aaaaaattat
     6841 ccaattagta tttcaaaaga aaaaaataga tgttaatact ttatctgagc agctacaggt
     6901 ctccaaggta accattcgta aggatttaga caagcttgaa agtaaggggc tgctgcgtcg
     6961 tgtgcatggc tatgcggtgc tcaatagtgg tgatgatttg aatgtgcgcc tgtcctataa
     7021 ttataacatc aaaaggcgga ttgctgaaaa ggctgccgag ctggtgcagg acaacgatac
     7081 catcatgatt gagtcaggat cgacctgtgc cctgttggca gaggtgctct gtcaaaccaa
     7141 acaaaacatc aaaatcatca ccaactcctg ctttattgca agctatattc gtcagtatag
     7201 tagctgtcag cttatcctgc tggggggcta ctatcagcct aattctgagg tgaccgtcgg
     7261 cccactttta aaggaaatga tttcgctttt tcatgtggat cgtgtttttg ttgggacaga
     7321 tggctttgat ccggcaattg gctttatggg caaggacatg atgcgctcag agggcgtccg
     7381 ttacatggca gaggcttctg aggagcttat tatcctgaca gattctagca agcttagcaa
     7441 acccagtctg gttcatcagc tatcgcttga ggctgttgac cgtatgatca cagatgagca
     7501 attggaggca agcacctata agctcctgca agagcatggt attgccattg actttatatc
     7561 gtagcatagg taactcaaat gaaagaagaa cgtaaacgcc tgcttgccaa ggtcgcctac
     7621 ctgcattatg tgcagggcaa aagccaaacc gctatttcaa aggaaatgaa tatttaccga
     7681 acaacggtct gtcgcatgct tgccaaggct agggctgaag gcattgtgcg tatcgagata
     7741 gctgattatg atgctaattt gtttgccttg gaggagtatg ttcgtcaaaa atatggctta
     7801 gaaaagcttg atattgtatc caatcaaatg gaggacagcc ctagtgatac cttggtaaag
     7861 gtggccaaaa cagcagctga ggtcttgcgc agcacgatta aggatggtga taagattggg
     7921 ctatcgtggg gagcaacgct gtcaagcctg attgatgagc tggatcctaa agcaatgaag
     7981 gacattatgg tgtgtccctt ggctggaggt cctagtcata tcaatgccaa gtttcatgtg
     8041 aatactctgg tttatcgcct agcaaggatc tttcatggca atagctcctt tatcaatgct
     8101 atggtggttc aggaggacaa gcagctaacc agagggattt tgcagtccaa gtattttgaa
     8161 gaaaccctga cctattggaa ccatcttgac cttgctctgg tcggtattgg aggagaacca
     8221 aatggtcgcc agaccagtca atggcgtgat ttgttgactg ataaggatta taagcagttg
     8281 gcagatgaaa aagctgttgg tgaggtctgt tgtcgctttt ttgatcagga ggggcatggt
     8341 gttcatcagg aattacagga cagaacgata ggcatttcgc tggagcagct agcgcgtgtg
     8401 cctaagacaa tagctgttgc tgttggtcaa gataaggcca aggctatctt agcggcttta
     8461 aaggctaaat ttatcaatta cctcatcaca gataaggcta ctatcatggc tgttttggct
     8521 ttggatcagg atcagacagc tggtacctat ctctcatagc aatagcttga tcagaaaacg
     8581 attgttttct gattttttgg tgctcaaaaa ccttgcaaag catcattttt gcacaatagt
     8641 gctaaaaaat aaatacagca cataatatat tgacgaagga agtaaaaatg ataaaatgaa
     8701 cttatcaaag aaatgtaaac gattacaaac gcaagctgtt ttttacgaaa aaagcaaggg
     8761 taatccttac atgagcacgt cacaaaggag aaacaaatgg aattaattgt accagaccaa
     8821 atcatcatgg ggttaatcct aaatgcagga gacgcaaagc agcacatcta tcaagcccta
     8881 aagctggcca aggctaagga ctatgaggct agtgacaagg aattggcctt agctgatgat
     8941 gctttattag aggcgcataa tttgcagaca caatttttgg ctcaggaggc tagtggggca
     9001 aaggcagaca ttacagccct gtttgtccat tctcaggatc acttgatgac aactattaca
     9061 gaaatcaatt tgatcaaaga aatcattgag cttcgtaagg aattagcaga aaactaaaga
     9121 tcatatcaaa aggaggacgt tatgattaaa attggcttat tttgtgcagc aggcttttca
     9181 acaggcatgc ttgtgaacaa catgaaggtg gctgctgaga aaaagggcat tgcttgtgag
     9241 attgaagcct actcacaagg aaagctggca gactatgcac cagctattga tgttgccctc
     9301 ttaggtccac aggtggctta taccttggat aagtcagagg ctatctgtaa ggaaaacggc
     9361 attccaatag ctgttatccc aatggctgat tatggtatgc tagatggtgg taaggtgctt
     9421 gacttagcgc tcagcttgat aaaggaatag gagcttggtc atggctaata tgaatgctca
     9481 aaaaatcatt gcaccgatta tgcggtttgt taatatgcgt ggcattatcg ctctaaagga
     9541 cggtatgctg gcgattttac ccttgacggt tgtcggaagt ctttttctta ttgcaggtca
     9601 gattcccttt cagggggtca atgacgctat agcgagtgtc cttggggcag actggacaga
     9661 gccatttatg caggtttatc agggtacctt tgctattatg ggcttgattt cctgcttttc
     9721 gattggctat tcctacgcta agaattcggg cgttgagcca ctgccagcag gtgtgctgtc
     9781 tctgtcagcc ttctttatcc tgctaaggtc ctcttatgtg ccaaaagaag gtgaggctat
     9841 tggtgatgcc attagtaagg cttggtttgg tggtcaaggg attattggtg ccatcattat
     9901 tggtttagtg gttggtgcga tttatacagc ctttattcgt cgtcatatcg tgatcaaaat
     9961 gccagagcag gtgccacagg ccattgccaa gcaatttgaa gcgatgattc cagcctttgc
    10021 gatctttatc ctgtcaatgc ttgtttatat catcgcaaag ctagtgacag gtggtggcac
    10081 ctttattgaa atgatttatg ctgtgattca ggtaccccta cagggcttga ccggctctct
    10141 ttacggtgcg attggtattg cctttttcat ctccttctta tggtggtttg gtgtgcatgg
    10201 ccaatcggtg gtcaatggta tcgtgacagc gctgctcttg tcaaatctag atgctaacaa
    10261 ggccttgtta gcagcaggtg atttgtcttt ggctaagggt gctcatattg tgacgcagca
    10321 gtttttagat tctttcttaa ttttatcagg ctcaggtatt acctttggct tagtgattgc
    10381 catgattttt gcagccaaat caaagcagta caaggctcta ggcaaggtag cagcctttcc
    10441 ggctctcttt aatgtgaatg aaccggtagt ctttggcttt ccaattgtga tgaatccagt
    10501 gatgtttctg ccctttattt tggtgccagt tgttgcggcc ctgattgttt atggctctat
    10561 tgcgattggg tttatgcagc catttgcagg cgtaacgctg ccttggtcta caccagctat
    10621 tatctcaggc tttatggttg gtggctggca gggagctctt gttcaggctt tgattcttgt
    10681 cttgtcaacc cttatttact tcccattctt taaggttcag gataatattg cttatcaaaa
    10741 tgaattggca gctgaaaaag cttaacagta tgctgatatc aatcaccatg acttaaaaac
    10801 agtctttagt cactagctat agcattccta gagaagggct tagagaagga ggatttcttc
    10861 acgtaaccat ctcaatgagg tggttttttt gaaagagact cttagacaag tctatttttg
    10921 cacgatagtg caacgttaaa tgaatagctg aatgctatgg atatgatagg caaaatgttt
    10981 taaatatggt aaaataatta cgaaagaaag taatttaatt tcgtaagaaa caaaggaggc
    11041 ctaatatgac tgaagtaaag aatccctatt ttgggacatt aacagaaaga atgcaccgct
    11101 atcgtgaggc agttctagac aaaaagcctt atattgatgc tgagcgtgct attttagcaa
    11161 cagaggctta caaaaaacac caaaacaagc catctaatct aaaacgcgct tacatgctgc
    11221 aaaatatttt ggaaaacatg accatctaca ttgaggacga aagcttgatt gctggtaatc
    11281 aggcgtcttc taataaggac gcaccgatct ttccagagta cactcttgaa tttgtcctaa
    11341 atgagcttga cctttttgaa aagcgtgatg gcgatgtgtt ttacatcact gaagaaacca
    11401 agcagcagct ccgcgagctt gcacccttct gggaaaataa caatttgcgg gcccgctgtg
    11461 gtgtcctact accagaggag gttcaggttt atatggaaac tggcttcttt ggtatggagg
    11521 gcaagatgaa ttcaggagat gcccatttag ctgtcaatta ccaaaagcta ttagaggttg
    11581 gcttgaaggg ctttgaggag cgagctcgtg cagctaaggc tgcgcttgat ttgaccattc
    11641 ctgaaagcat tgataagtat catttttatg attctgttct gattgtgatt gctgcggtta
    11701 aggcttatgc agagcgctat gccaaattgg cgcgtgagct ggccaaaaca gctaatccag
    11761 agcgtcaggc agaattgctt gaaatcgcgc gtatctgtga caaggtgcct taccagccgg
    11821 cggaaacctt tgctgaagcg gtccaatcag tttggtttat ccagtgtatt cttcagattg
    11881 agtcaaatgg gcattctctt tcttatggcc gatttgatca atacatgtat ccatatgcca
    11941 aggctgattt ggaggctggt cgtgaaacag aggattctat cgttgagcgc ttgactaacc
    12001 tttggataaa gactctgacc atcaataagg tacgcagtca ggctcatacc ttctcatcag
    12061 caggtagtcc gctgtatcaa aatgtcacca ttggtgggca aaccagagat aagcaagacg
    12121 ctgtaaatcc tctatcctac ctagtgcttc gcagtgtggc tcaaaccaaa ttaccacaac
    12181 caaacctaac cgttcgatat cacaagggct tggataatcg ctttatgaat gaatgcattg
    12241 aggtcatgaa gcttggcttt ggtatgccag ctatgaacaa cgatgaaatc atcattccgt
    12301 cctttatcaa aaagggtgtc cttgaagaag acgcctacga ttattcagca attggctgcg
    12361 ttgagacagc tgttccaggt aaatggggct atcgctgtac tggtatgagc tacattaact
    12421 tcccgaagat tttgctgatc accatgaatg atggtattga cccagcctca ggcaagcgct
    12481 ttgcaacagg acatggtcac ttcaaggata tgacctctta tgacgagcta aaggcagctt
    12541 gggacgcgac tctgcgtgaa atcactcgca tgagtgtcat cgtagaaaat gccattgacc
    12601 ttgggcttga acgagaggtg ccagacattc tttgctctgc attgactgat gattgtatcg
    12661 gccgaggcaa gacgctcaaa gaaggtggag cagtctatga ttacatctca ggcttacagg
    12721 tggggattgc taacctgtct gattccctag ctgcactgaa aaaattggtg tttgaggagg
    12781 gtcgcctaac cactgatgag ctctggcatg ctctagaaac agactttgca ggtgagcgtg
    12841 gtgaagagat ccgtcaaatg ctgattaacg atgcaccaaa atatggtaat gatgatgact
    12901 atgctgatag cttagtggtt gaagcctatg atacctacat tgatgaaatt gctaaatacc
    12961 ctaatacgcg ctacggacgt ggtccgattg gtggtattcg ttactcaggc acctcatcta
    13021 tttcagctaa tgtcggccaa ggtaagggaa ccttagctac cccagacgga cgtcatgcag
    13081 gaacaccgct tgctgagggc tgctcaccag agcacagcat ggataaaaaa ggaccaacct
    13141 ctgttttgaa atccgttgcc aaattgccaa cagatgaaat tgtaggtggg gtcttgctca
    13201 accaaaaggt taatcctcag acactagcaa aagaagaaga caagatgaag ctgatggctc
    13261 tgcttcgtac cttctttaac aggctgcatg gctatcatat tcaatacaac gtcgtctcac
    13321 gtgaaacgct tattgatgct caaaagaatc ctgaaaagca ccgcgatttg attgtgcgtg
    13381 tggcagggta ttcagccttc tttaatgttt tatcaaaagc tactcaggac gacattatcg
    13441 aacgtaccga acacacacta taggagaaca gttacttatg gaatacatgc tagatactct
    13501 aaatctagag gctattaaaa agtggaatcg cattttaccc cttgcagggg taacctcaaa
    13561 cccttcaatt gctaaaaaag agggagatat tgattttttt gaacgcatta gagaggttcg
    13621 tgcgatcatt ggagataagg cctctattca tgtgcaggtc gtggcacagg attatgaagg
    13681 tattttaaag gacgctgcgg ctattcgtca gcaatgtggt gatagtattt atgtaaaggt
    13741 tcctgtgaca acagagggcc tcgcagcgat caaaacccta aaggcagagg gctatcacat
    13801 cacagcaaca gctatctata ctaccttcca gggcttactg gccatcgaag caggagcaga
    13861 ttatctggcg ccttattaca atcgcatgga aaacctcaat attgatccgg aggctgtgat
    13921 tggccagctg gcagaggcca ttgatcgtga atgctctgac agtaaaatct tggcagcgag
    13981 cttcaaaaat gtagctcagg tcaaccaagc ctttgccttg ggtgctcagg ccatcactgc
    14041 tggtccagat gtctttgagg caggctttgc gatgccatct atccaaaagg ctgtagatga
    14101 ttttggcaag gattgggagg ccattcatca tcgtcaaacc atctaaaagc catctaaccc
    14161 atcgttatat gagcaagagc agggacgctt ctatcagcat agctagacta gtcttgctca
    14221 ctcttagatg gtgagaagcg tcaaaaatct gatttagaaa gaggaacatc atgaaagtat
    14281 ttgcaagtcc atcacgctat attcaaggga aaaatgcctt atttaccaat agtgacatca
    14341 tcaaaaagct agggcaaaag ccggtattgc tctgtgatga tattgtttac ggcattgtcg
    14401 gagaacgttt tgagggctat ttaagtgagc atgatctacc acctgttcac gtagccttta
    14461 atggcgaagc gtctgataat gagattaatc gtgtcgttgc cattgctaga gaaaatgata
    14521 atgatgtcat tatcggactt ggcggaggca agaccattga cagtgccaag gcaatcgctg
    14581 acatcttgga ggtaccagtg attattgctc caaccattgc ctccactgat gctccgacat
    14641 cagccttatc ggttatttac acagatgagg gcgcctttga aaaatacatt ttctattcta
    14701 aaaaccctga gcttgtcttg gttgataccc aggttatctg tcaagcacca aagcgcttgc
    14761 tggcttcagg tattgccgat ggcttagcta cttgggtaga ggcacgtgct gttatgcaaa
    14821 aaaatggtga cacgatggca ggtggcaacc aaaccttggc aggacttgct attgctgagg
    14881 cctgcgagcg taccctattt gctgacggtc tcaaggcaat ggctagctgt gagaaaaagg
    14941 tcgttactcc agccttggaa aatgtgattg aagccaatac tcttttaagt ggccttggct
    15001 ttgaaagcgc aggacttgct gctgctcatg ctattcacaa tggctttaca gctttgacag
    15061 gtgacattca tcacctcact catggtgaaa aggtggccta tggcacccta acacagcttt
    15121 tcctcgaaaa taaatcaaga gaagaaattg accgctacgt tgacttttat caggctatcg
    15181 gaatgccgac aaccctaaaa gaaatgcatt tagacaccgc caccgaagag gatttcttaa
    15241 aaatagggcg tcaagcaacc atggcaggag aaaccattca ccaaatgcca tttaccatca
    15301 cagcagagga cgttgccgca gcacttgttg ctgtagatgc ttacgtttgt agcagaacat
    15361 aatgcaggcc tactaaagcc ttcatagtcc tgtcagggcc tgttgctggt ggctcttgtg
    15421 tgagataggt tgcggaaaca gcaaggcttg actttctaaa gacctctcag ctttcctgtt
    15481 tgcagtgtgg gaacgcttgc tttacgacta aggctagtca tgactattca aggtagacag
    15541 ccccctccca atgttgacat ctagtaaagt caagcgatat tcaggctgta gacaagcctt
    15601 agcggtcacc tcatcaactt tgaggactgc agacaagaga ccctatgagc gaagcatgtc
    15661 aaatgagcct tcagtcatcc ttttgtagct gactgttccc ttgaaagtca gcaacttgaa
    15721 ggctctaatg tctaggctca cagctaagtg tggagagtca gtagaggctt gggctttaac
    15781 tgctgtgtga ctgagatggc aagcctctca tctaacaagc cctttagcgt cactcacagt
    15841 taccataacg gtaacaggca caaaacgaac caattaggaa tctggtatcc agaaaactaa
    15901 tcttggttcg ttttttgttt aggagctgat acttgtctta gcctcatagg gctttaagtg
    15961 tgagtcaccc aagcctattc gttagcaggc ttaattgatc ccactcgcag tagcattaac
    16021 tagcataaaa ggcttaaatc cccccttact agctgccaat cagagctatc ttaggggtgt
    16081 tctccagcaa ttctttcccc agtagcctaa ggtcttgatt tagtgaatcc aaatgtctcc
    16141 tagcacccta gagcttctca gtcctctcag ctattactag aagttatcaa taagcataag
    16201 gctgccgcta gctttgtggt ataatgacac aacaactttt taaggaggtt agctatgatt
    16261 cggaagattg gtattgtcag cttgtctagt ggtatgcttg gcgaggctaa tgtcaagcac
    16321 gaattggatt taggcttagc gcgtttaaaa cagctaggct tagaggtaac gatactccca
    16381 aatgctttaa agggcataga ctaccttgat cagcaccctg aagcaagggc agcagatatg
    16441 attcaggcct ttgcagatcc gtctattgac atgattttgt gtgccattgg tggggtggat
    16501 acctatcgcc tcttgcccta tctgtttagc gaacatcagc tacaagatgt tgtcaatcaa
    16561 aaggtttttc ttgggttttc tgacaccacg atcaatcatc tgatgcttca caagcttggc
    16621 atcaaaacct tttatggtca gtcctttctt gccgatattt gtgagctggc tgatgacatg
    16681 cttccttact cgctggctta ttttaaagag cttcttgaga caggaacgat cgctgagatc
    16741 agacccagtg agcagtggta tgaggagcgg actgatttta gcgcaaacag ccttgggacg
    16801 cagcgaatag ctcatcgtaa tcaaggcttt gaattattaa aaggtccgtc cttattcaag
    16861 ggagagatac taggtgggtg tttagagtca ctttatgaac tattggattc ctcaaggtat
    16921 tcagataatg ccaagctctg tgagcaatac cagctctttc cagatctgtc tgactgggca
    16981 ggcaggctct tgcttctaga aaccagtgaa gacaagtcag atccagctca ataccgccga
    17041 atgcttgaaa ccctcaaagc aacagggatt ttttcggtga tctctggatt attggttgga
    17101 aagccgatag acaacagcta ctatgacgac tataagcagc agctgctagc tgttgttgat
    17161 aatgatatcc ccattcttta caatgtcaat gttggccatg ctaccccaag agccattgtt
    17221 ccctttggtg tcatggctgt ggttgatgcc aaagagcagg tcattcgatt tgtccctgat
    17281 gagcatacag accaaaatga cgtctaacaa atcaaaacag aaagtgagag agtctatgcc
    17341 aaaggttgac acgataacgc aggtttattt tatccgccac gcagagccta actatcaaaa
    17401 ccacaatgac gtgactagag agctctccga gcatggggtt aaggcgagcc aagacctggt
    17461 taggcaacta gcagaggtgt cgattgacgc cttttattcc agtctctata aacgctctat
    17521 tgacaccatt gccccactag cagctagtag ggcaatggaa attaagctga ttgacgattt
    17581 gagagagcgt aagctagctg atgcttggat agaagacttt gtcgacacag ccaaaaagca
    17641 gtgggctgat ttcaccttta aattgccgac aggcgaaagc ctgcaagagg tacaagacag
    17701 aaatatagca gctcttaacc gtattttaaa agaagcaaaa ggcaagacag tagtcattgg
    17761 cacacatggc acagcactgt caacccttat caactactat cagcctgact ttggttttga
    17821 ggatttcgac cgatataagc atgtctttcc ttggatagtc agagctagct ttgatggtga
    17881 caagctgctt gggcttaatg agtttctagt ctgacaagtc tagccttgat ccagctatta
    17941 taggtgatga cagcaacaaa atcagataat taaccctttc attaaaaaaa acaaaacctc
    18001 ggagacaaac tagccagcag ctatttctca tgagtaatca acatgttaaa atcttctttg
    18061 gagatattag acaaccataa ttattatatc atcaaaggag agagatgaca aacaaaacaa
    18121 agcgtacagg attggtacgc aagtacggtg cctgctcagc agctatcgcc ttagcagctc
    18181 ttgcaagcct gggagcaggt aaagcagtaa aggcagacca gccagcagca ctaaaatatc
    18241 cagaacctag agactatttt cttcatactc gtgaaggtga tgttatttat gatgaggata
    18301 taaaaagata ttttgaggat ttagaagcct atttaacagc tagacttggt gggattgata
    18361 aaaaagtaga agaagctgcc caaaagccag gtattccagg tcctatgggg cctgctggcc
    18421 ctcaaggtcc taagggagac aagggggatc caggtgcccc tggtgagcgc ggtccagctg
    18481 gaccaaaggg cgatacaggc gaagccggac caagaggtga gcaaggccca gccggacaag
    18541 ctggagaacg tggaccaaag ggtgacacag gtgctccagg ccctaaagga gaaaagggtg
    18601 atactggtgc agttggtcct aaaggtgaaa aaggtgatac cggagcaact ggacctaaag
    18661 gagacaaagg cgaacgcggc gaaaaaggcg agcaaggcca acgcggtgaa aaaggcgagc
    18721 aaggccaacg cggcgaaaaa ggcgagcaag gccaacgcgg cgaaaaaggc gagcaaaaac
    18781 caaagggtga tcaaggaaaa gatacaaaac catcagctcc aaaagcacct gaaaaggctc
    18841 ctgcaccaaa agctccaaag gcttcagagc agtcagctag ccctaaggta ccagctctta
    18901 agtcagcacc aagcaaatca gcgtccccag caggtcaaaa agcagtccta ccagccacag
    18961 gagaagcaag ccatccattc tttagcttgg cagctctcag cgtcatcgct agcgcaggct
    19021 tgctaaccct aaaaagaaag aaaagctaag ctagccattg tgtctttccc ctatggcaat
    19081 agctaatcac aagctttaga gaggtctttt ctgacctctt tttaatatat actgaataca
    19141 tgcttacctc aaaaagacag tagtctaagt ttgactactg tctcaaaaat catttttacc
    19201 taaagccttg atccccttga taaatggtag agaagagctt tatttctagg gcctttgact
    19261 tcagtttgaa tgttgttagt tttccttacg ttttatagct gctacaccag ctgtagccat
    19321 cactgcaagt gcagctgcgg tgaagaatgg gttcacagcc tcacctgttg ctggcaattg
    19381 attagtcgtt ttcttcatct cagctttagc tgccgctgct ttagaagctg tgtgagctgg
    19441 cgctgctact ttacctgctt gatcagcttt ttcaggactg agtggtttag cctctggctt
    19501 agtttctggt ttggtttctg gaactttagg tgcgtcttct tgtggttttg aatgtggact
    19561 tgatttttta atatctttag catctagggc aacgcttctt tcctcacctg ttgtagcttg
    19621 agaaagcttt ttgccgttga caaaaagctc atagaaagtg ccatctagaa gccctttaga
    19681 aaatacagct ttgccatcag ctcctgttgt tactttctct atcacacgac ctactctatg
    19741 ctttagagtg acttcttgcc ctgataaagg ttcagcatct tcattacgaa cgacaacaac
    19801 caacggtgtt ttactgtatt ctggctcaac tgttcctttt ccgtcaacag taaagctagc
    19861 tgaatgcttg tcgccatcaa cacctgttcg tacagtatag ccttgaggaa cgccgttcac
    19921 aaaaatggat aaacttcttc ctaaaggaag cttgtcaaaa acagcttgcc ctttttcatc
    19981 tgttgtcaca gtcgcaagtg tctttctgcc acttgttata tctaccactt ggacgtcttt
    20041 tccagataat actttaccct cagagtctat aactgttgcg gtaaaagcaa agctaccttc
    20101 aataacatca tcatgatggt ggtgtgcatg atcactgtga tgactactgt gcccatcgtc
    20161 aaaaggctta gaaacatcaa tcttatccaa taaaataaca tgatgatgat cgtcatgtgg
    20221 atacatcaag gccttaccct ctgaagtatc caataattga atcttgtcta atggcaagcc
    20281 tgtatttttg gcaatataag ctttttttac ggcaataata tcttcagctg attgattagt
    20341 gtctagcggt aatttatcag ctgctgctac aggatttgcg gtttctgatg cttttgtaat
    20401 tggtttatca gccatcacct cagtgctgtc agataactgt tgattagctg tatctgcagt
    20461 atctttatcc tcacctaacc tcggttggac tacagtgtga ttatccactg ctggtgattc
    20521 atcagcaaat gctactgacg agttagttga catcgctaaa ccagcagcca ttaaagcagc
    20581 tgggataagt aaagagtatc gggtaatttg attctttttc attaataact ccttataact
    20641 attattcatt ttaattaatt aaccagttaa ctatatcaat ctatcaaaaa aaatatagta
    20701 tgtcaacccc ttaaagtgat ttaatcagaa caaacgtata aagaaaatca tttagtgaaa
    20761 aagacgccta ttttagctga aatagatcca ttataaaaga ggtgttgtaa agtgacccaa
    20821 tattcgtcta ttttagttgc aagcgttcta atgggaatag aaaaagggca gttgcttgca
    20881 acaactaccc aatgtagaat cgttaaagac ggtgacagaa aataactgtt aactgaacta
    20941 cctcaaaagt tagaccaaag atttaaccgt tggaggttga tttgtagagc ggttattttt
    21001 ttattgttat gtttacaacg actaggctca tcagtgcaag ggagaaggac ttccatatta
    21061 agaaatatat agacatctcc tagatgagac gtgtaatgaa tgggttgaac aaatagttgc
    21121 ttaattttgg gataagggtt ataatgaaaa tagaaaaagg gcagttgctt gcaacaacta
    21181 cccaatgcag aaccgtttaa gacggtggct ggttttatag ttaaaaaata accgttaact
    21241 ggccaaagtt aaagacggtt attttttatt gtcatttttg aagattttat agcacaaact
    21301 gataagtgca atagtaaagc tactaaagcc taaaagggtt tgtaccactt caaaagctgt
    21361 caatgctttg gctcctcctt tctgttagat tttgatgaac tgcccatagg cctcacctac
    21421 ctttcagaaa taagagcccc cgtcttaacc tttctgcttt atttatagca tattgttatt
    21481 aaggttgact attcagactc gtctaaagaa gtataatagt tgcttaattt tgggataagg
    21541 gttataatga aaatagaaaa aggtagttgc tcgacacaac tacccatgca gaaccgttta
    21601 agacggtggc atgttttatg ttattaaaaa ataaccgtta actcgccaaa gttaaagacg
    21661 gttatttttt attgtcatct ttgaagattt gatagcacaa actgataagt gcaatagtaa
    21721 agctactaaa gcctaaaagg gtttgtacca cttcaaaagc tgtcaatgtt ttgactcctc
    21781 ctttctgtta gattttgatg aactgcccat aggcctcacc tacctttcag aaataagagc
    21841 ccccgtctta acctttctgc ctttttatta tagcatactg tatctctgat tgactagctt
    21901 aagaaggagg ggatgtgatt tggatacaaa tttttgttaa cttttttaaa gtctccaaat
    21961 gatttaaaaa aatgatatta atgctctaag taagaatatt aataatatgg ttttaccact
    22021 tattgtatga ggtatcattt ctaaagagtt atttttcaga cagaaggctt gttaaagcaa
    22081 acagaagcaa tactaaaggc attagatgat aatcaaggcc tttttcatgt cttaaaatga
    22141 gtattctagc tgttgtgttg gatagaattc atataatgat ttaactgctt ttgatttttt
    22201 aaaacgattg ttttatgagg atactgttta ataactgctt tatagttatt taacttattt
    22261 tttgagcgtc cgtccaacag aatccatttc ataaattcaa catcaaattt ttcattacag
    22321 ttttcagcca tatcaggacg tgtttgcccc ctatagttta aatatcgctt aaaagctcgg
    22381 taaaaacaat taaatctatt aaagttaaag tatataatgt gatcagcctc tctcatacgc
    22441 tcttcataaa gacagcttga ataattacct tcaataatcc aatgtttttg tgacataaat
    22501 gttgatatat cagagaccat ttgactaact gttcgctctt gccagtttga tgcaaaatga
    22561 attttgtcta aatgaagtac agcacaattg tagtgttgac ctaaaacatt tgctaaagtc
    22621 gactttccag aaccactatg gccaattatt acaactttca atttttatct cctttgtcaa
    22681 tgctgtgttt tgattcatat catagcataa agaatatatt ttggggacaa accctcttta
    22741 ggcaagcaaa aaagcctttc tagcagaggc tttttttgaa tttggatacc tcctacaacg
    22801 atttcctaca attttttctg acaataataa tcgataatgc cgattttaaa ggctttttat
    22861 tttgataaat tattgaaaaa tggttatcag aaaaataatg tgggacaaaa aagggacatt
    22921 tccatataaa tttggtataa aaatttaaaa tcagatttta tcatttttaa tatattctgt
    22981 ttgattagta tatgagattt agtattac
//
LOCUS       DARYSY010000037        21749 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYSY010000037 DARYSY010000000
VERSION     DARYSY010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21749
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(62..832)
                     /locus_tag="TVR04_001313"
     CDS             complement(62..832)
                     /locus_tag="TVR04_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1270003.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGIIDRIIPERGYF
                     SSEIIEMIRSHLIDEITQLQAKSLEELLDQRYQRFRKY"
     gene            complement(829..1695)
                     /locus_tag="TVR04_001314"
     CDS             complement(829..1695)
                     /locus_tag="TVR04_001314"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1270004.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(1704..3068)
                     /gene="accC"
                     /locus_tag="TVR04_001315"
     CDS             complement(1704..3068)
                     /gene="accC"
                     /locus_tag="TVR04_001315"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1270005.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSAAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEVARRIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDLQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRVDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(3102..3524)
                     /gene="fabZ"
                     /locus_tag="TVR04_001316"
     CDS             complement(3102..3524)
                     /gene="fabZ"
                     /locus_tag="TVR04_001316"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1270006.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVIPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(3521..3994)
                     /locus_tag="TVR04_001317"
     CDS             complement(3521..3994)
                     /locus_tag="TVR04_001317"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1270007.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRSMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(3996..5228)
                     /gene="fabF"
                     /locus_tag="TVR04_001318"
     CDS             complement(3996..5228)
                     /gene="fabF"
                     /locus_tag="TVR04_001318"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1270008.1"
                     /translation="MTLNRVVVTGYGVTSPIGHSPEELWSNLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPNRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAISN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(5244..5978)
                     /gene="fabG"
                     /locus_tag="TVR04_001319"
     CDS             complement(5244..5978)
                     /gene="fabG"
                     /locus_tag="TVR04_001319"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1270009.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKVNLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILSQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(5995..6915)
                     /gene="fabD"
                     /locus_tag="TVR04_001320"
     CDS             complement(5995..6915)
                     /gene="fabD"
                     /locus_tag="TVR04_001320"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1270010.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQHAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEASLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(6928..7914)
                     /gene="fabK"
                     /locus_tag="TVR04_001321"
     CDS             complement(6928..7914)
                     /gene="fabK"
                     /locus_tag="TVR04_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1270011.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVVN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(8109..8333)
                     /locus_tag="TVR04_001322"
     CDS             complement(8109..8333)
                     /locus_tag="TVR04_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1270012.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(8391..9365)
                     /locus_tag="TVR04_001323"
     CDS             complement(8391..9365)
                     /locus_tag="TVR04_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1270013.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIERRH
                     ISTVEMTSDLATRVAEQLLARSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGARGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(9365..9799)
                     /locus_tag="TVR04_001324"
     CDS             complement(9365..9799)
                     /locus_tag="TVR04_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1270014.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     NRLHAKFHKNMVGHVVADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(9879..10670)
                     /locus_tag="TVR04_001325"
     CDS             complement(9879..10670)
                     /locus_tag="TVR04_001325"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1270015.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK"
     gene            complement(10996..12132)
                     /gene="dnaJ"
                     /locus_tag="TVR04_001326"
     CDS             complement(10996..12132)
                     /gene="dnaJ"
                     /locus_tag="TVR04_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1270016.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKEVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(12289..14118)
                     /gene="dnaK"
                     /locus_tag="TVR04_001327"
     CDS             complement(12289..14118)
                     /gene="dnaK"
                     /locus_tag="TVR04_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1270017.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQAALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(14523..15092)
                     /gene="grpE"
                     /locus_tag="TVR04_001328"
     CDS             complement(14523..15092)
                     /gene="grpE"
                     /locus_tag="TVR04_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1270018.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSADTVADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(15137..16171)
                     /gene="hrcA"
                     /locus_tag="TVR04_001329"
     CDS             complement(15137..16171)
                     /gene="hrcA"
                     /locus_tag="TVR04_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1270019.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDFYQLVKAFDFEAFKLE
                     DVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQ
                     FAIPKNFMNRDLLVLKVIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYRFLDEEQRLALSIRQSLSEEEMVTVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(16620..17192)
                     /locus_tag="TVR04_001330"
     CDS             complement(16620..17192)
                     /locus_tag="TVR04_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1270020.1"
                     /translation="MRRRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     GQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQATSKHKTVYAIYRDREDSIRAYLSWLSQGTGGDKKLYQSLATEKGYKRPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(17189..17932)
                     /locus_tag="TVR04_001331"
     CDS             complement(17189..17932)
                     /locus_tag="TVR04_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1270021.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGIYLFIKPEKQAVGPKANQTAPAP
                     KAAKQAKKTTDLPKVSATDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQERLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDSLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASAQYITAHSLSLEEYLTRLKEKK"
     gene            complement(17922..18629)
                     /locus_tag="TVR04_001332"
     CDS             complement(17922..18629)
                     /locus_tag="TVR04_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1270022.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRESDNEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(18704..20041)
                     /locus_tag="TVR04_001333"
     CDS             complement(18704..20041)
                     /locus_tag="TVR04_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1270023.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAIGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLPLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEMGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEMVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQMPAPIHSFKN"
     gene            complement(20056..20322)
                     /locus_tag="TVR04_001334"
     CDS             complement(20056..20322)
                     /locus_tag="TVR04_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1270024.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(20586..21701)
                     /locus_tag="TVR04_001335"
     CDS             complement(20586..21701)
                     /locus_tag="TVR04_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1270025.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQASPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRDGKRGYGYSYNPD"
BASE COUNT         5976 a         5487 c         4126 g         6160 t
ORIGIN      
        1 taaagaagac ctctgtaact cctagctaac tgctagcctt acagaggtct ttttgatgtc
       61 cttaatattt tctaaagcgc tggtaacgct gatccagtaa ttcctccaag gacttagcct
      121 gtagctgagt gatttcgtca attaagtgtg atcttatcat ctcaataatc tcactcgaaa
      181 aataaccccg ctctggaata atccgatcaa tgatgcccat ttgataaagc tcagctgcgg
      241 taattttcat gagctcagca gcttcagtag ccctagagcc atccttccag agaatagagg
      301 caaagccttc tggactaaga acagcgtaca tggtgttttc cagcatccaa acctgatcag
      361 caacagctaa ggctaaagca ccgcctgatc cgccctcgcc aataataata gcaatgatag
      421 gaaccttgag gtcactcatt tccatcaagt ttctggcaat agcttcacct tgaccgcgct
      481 cctcagcacc gacgcccgga taagcccctg ctgtattgat aaaggtaatc accggacggc
      541 caaatttttc agcctgcttc attaagcgta aggccttacg atagccctca ggatgcggtt
      601 gcccaaaatt tctagccaga ttatcttgaa gattttttcc tttttgaata ccaatcactg
      661 tgactggctg atcagccaaa taggcaatcc caccaacaat agagccatca tcagcaaact
      721 gacgatcccc atgcaactcc ataaactcat caaaaatcag gctggcataa tctagagctg
      781 tcattcgacc ctggtcacgc gcttccttta atattcttgc gacgtctgtc atgatacacc
      841 tccatgaaat gccaccaaat gagcaatccg atcacgcagg tcagtccgct tcacaatagc
      901 gtcaacaaag ccatgctctt ttaagaactc tgccttttga aagtcatctg gtaaattttc
      961 tctaactgtc gtctcaatga cgcgtcgacc tgcaaaacca accaaggact gaggctctgc
     1021 gataatcata tcgccctcca ttgcaaagct cgctgtcaca ccacctgtgg tcggatcagt
     1081 taggatagtc aggtaaaaaa gcccagcatt tgaatgtttc tttacagctg cagaaacctt
     1141 agccatctgc atcagactca taatgccttc ttgcatacgg gctccaccag acgctgtaaa
     1201 aataacaact gggagccgct cactaatagc cagctcaaat aagcgagtga ttttctcacc
     1261 aacaacggtc cccatgcttg ccatgataaa atgcgaatcc atgatagcta gagcaagcct
     1321 ttgtcccttg accagagctg ttccagtcag gacagcctca tgcaagccag tagcctgcct
     1381 ggccttttgc agcttggctt ggtagtctgg aaatcttaat ggatccttgg tttcaatatc
     1441 tgtaaacaat tcctgaaaag agccttcatc aacggttaaa gtcaagcgct cctgagcaga
     1501 aatcctaaaa ttataggagc aggtcggaca aatctttgcc ggccccagat ccttttgata
     1561 aatcatgtgc ttacaggcag gacacttggc aaataattcg tctggcacct ctggaacatt
     1621 acgactgaca gagcttttga gagaattatt aggagtaata cggatatatt tgtctttttt
     1681 actaaataag gccatatcta ctcctaatct ttattgtagc tgggtaaaaa ggtttccatc
     1741 aaaaacgacg tatcgtaatc acccgcaatc acttgcttgt ctgaaatcaa gtccatctga
     1801 aaatcaatat tggtcataat cccttcaatc tctaactcaa acagagccct ttgcatcttc
     1861 atcaaagcat caaatcggtt atcaccatga acgataatct tagcaatcat actatcataa
     1921 taaggcggta tcgtataacc actgtaaaca gcagaatcaa ccctaagccc aacacctccg
     1981 cttggtaggt aaagatctgt aatcttacca gggcttggtg caaaattaaa gcttggattt
     2041 tctgcgttaa tacgacactc aatagcatgg ccagtaatca caatatcctc ttgacgaact
     2101 gacaaaggaa gacctgctgc gatccgcaat tgctccttga caatgtcaac gcctgtaaca
     2161 aactctgtta cggggtgctc tacctgaaca cgcgtattca tctccataaa gtaaaaatca
     2221 ccgctagctt catctaataa gaactcaatt gtgccagcat tctcatagga caccgctttg
     2281 gcagcacgaa cagcagcttc acccatcctt tgacgcagtg ttgtgccaat cgcaatcgaa
     2341 gggctttcct ccagtacctt ttgattgtta cgctgtaagg agcaatctct ctctccaagg
     2401 tgtatcacat gcccctgtaa atcacctaaa atttgcacct caatatgcct tgccggataa
     2461 ataaccttct ccaaatacat ggcaccatta ccaaaagctc ctagagcttc ttgactagca
     2521 gcgttaaagg cagcctctaa atcagcctcg gattcaacct ttcggattcc tttacctcca
     2581 ccgcctgcag cagcctttag catcactgga tagccaatcc gccttgcgac ctcaagggcc
     2641 tcttgggcat tgtaaacctc gccgtctgag cctggaataa caggaacacc tgccttaatc
     2701 atctcagcgc gagcgttgat tttgtcgccc attttatcca tgacagctgc tgaggggcca
     2761 ataaacttga tgttcatttc ctcgcacatg gtcacaaatt ttgaattttc acttaaaaaa
     2821 ccaaaccctg ggtggatagc ctgcgcccct gtcaccacag ctgctgataa gacagaattc
     2881 atattgagat aggattcctt tgatcttgac ggtccaatac agatggcttg gtctgccaag
     2941 atcgtatgta aagcctcttt atcagcctcg gaataaacag caactgtgga aatgcctaat
     3001 tctcgtgctg cacgaataat ccgcactgct atttcaccac gattggcaat taagattttg
     3061 ttaaacatag gttctttttt cctccacaga cgattagtct tttactgccc aaaagcaaag
     3121 gtcaaggtcc cactagctgc taatttgcca tcaacctctg ccttggcttc gacaactgct
     3181 attgtcccac gacgcttaat aaacctagct gtcatgacta gctggtctcc cggaatcacc
     3241 tgctttttaa attttacctt gtccatacca gcgtaaaaaa caagcttgcc tttattttcc
     3301 tcttttgata gctccaagac gccagcagtt tgtgccaagg cctccatgat caaaacacct
     3361 ggcatgactg gatactgagg aaaatgaccg ttaaagaagg gctcattgat agtgacattt
     3421 ttgatggcaa caatttcatc gtctgaagcc tctaaaatcc tatcaacaag cagcattggg
     3481 taacgatgtg gcagtgcttc ttgaatctgt tttatatcca tcatttaatg cgtaccaatc
     3541 cttgtccaaa ctcaaccacg tcctcattgg ccactaaaat ctctgtcacg ataccgtcgc
     3601 aaggagcagg aatctcgttc atgaccttca tcgcctcaac aattaacaat gtctgtccct
     3661 ttttaacgct atcaccaaca gtaacaaatg gaggcttgtc aggaccagct gcaagataag
     3721 ccacaccaac aagaggactg tcaactactt ctccttctgg ctcttgcaga cctgaagaag
     3781 caggaattga ttcctgttta gagacaatct cctgcgtcag gctaataggg gctacctcct
     3841 ggtgcaaagt aacaggctcc ggagctggag ctgccatcga acggtgctca tttttactaa
     3901 ataacagctc cccatcactt gatttgaatg aaaattcgcg taggcttgac gcatcaaact
     3961 gtgccatcaa atcctttatc tcttgaatat tcattttaat cctcccaacg cttaaaggct
     4021 aatacagcgt tatgacctcc aaagccaaag gtatttgaaa tggcataacg aatatcggct
     4081 tcttttcctt ggccaaaaat aacatttgct tcaatgtcgt ctgacagctc ctttgtccca
     4141 gctgtcattg gaacataatt gtgacgtatt gcttctatgg ttgcaatagc ttccacagca
     4201 ccagctgccc ctagtaggtg acctgtaaag gacttggttg atgagacagg aacctcttta
     4261 ccaagcactg caacgatagc ttgactttct cctttttcat tagcaggagt tgatgttcca
     4321 tgagcattaa cataatcaat agccgctgca tcaataccag cctcctgcaa ggctagatta
     4381 atggccttac gagcaccaag tccttctggg tgtggtgagg tcatgtggta agcgtcacag
     4441 gtattgccgt agccaacaat ctcagctaaa atagtcgctc cacgcttttg agcatgctct
     4501 aagctctcca agaccagcat acctgagcct tcacccatga taaagccgtt tcgatcctta
     4561 tcaaatggaa tagagctgcg gtttgggtcc tcagttgttg acaaggcagt taggctttgg
     4621 aagcctgcaa tggcaaattt tgtaatggct gcctctgagc caccaaccat catcacgtct
     4681 tgaaggccaa acttaatcgt gcgaaaagca tctccaatag cgtcatttga agaggcacag
     4741 gctgtattga ttgacttaca tacgccttgg gcattcagct tcatggcaac attaccagcc
     4801 gccatatttg gcaaggcctt tggtagagtc atcggcttaa cgcgctttgg tcctttttca
     4861 tgtaaccgaa tcacctgctc ttcaatctct tgaatgcctc caataccaga cgctacaata
     4921 acaccaaagc ggtcagaatc aatcgcttca atgtctaagc cagcatgttc aatcgcttct
     4981 gtcgcagcat ataaggcata caaggagtac atatcaaaac gattaaggtc ctttttgaca
     5041 aaatacttat caaatggaaa atcctgaatc tctgctgcat tcttaacagc gaagtcactc
     5101 gtatcaaatt ttgtaatcgg cttaatacca atatgacctg cctttaaatt tgaccatagc
     5161 tcctctgggc tatgcccaat tggggaagtc acgccataac ctgttacaac tactctgttt
     5221 aatgtcattt taatacctct attttattgc attgtcatgc cgccgtcaat ggcaagcacc
     5281 tgaccagtaa tataatcctg actagctagg aagcttgctg cctgagcaac ttcctgcccc
     5341 ttaccaatac gcttcattgg aatttgactt aaaatctgct cctgcatctt ttcagaaagg
     5401 acacctgtca tatcagattc gatgaagccc ggtgcaatcg catttacccg aataccacgc
     5461 gccgcaacct cacgagcaac tgacttggta aagccaatca agcctgcctt ggacgctgca
     5521 taatttgctt gaccgatatt tcctgttagg ccgacaacac tagacacatt gatgatagca
     5581 ccctgacgag cctttgtcat cggctttaag accgattgtg tcatgttaaa tgctcctgtc
     5641 aggttgactt tgagaacacg ctcaaagtcc tcctctgaca tcttaagcat taatttatca
     5701 ttagtgatgc cagcattgtt aatcaaaatg tccacagagc caagctgctc aatagcctca
     5761 tcaaccattc gcttagcatc agccccctct gaaacatctc ctgagatcgg cacaaccttc
     5821 acaccgtaat ccttaaaggt ctccaccagc tcatcagaaa ttgctgagcg accattgaga
     5881 acgatgttgg cgcctagtcc tgcaaattga tgagccattg ctagtccaat gcctcttgtt
     5941 gaccctgtga taaaaacgtt ttttccttta atttccatag cttagcattc cctcctattt
     6001 tcccaaatac aattgtaggc ttggcatatc ttcaacactg ctgcatagca gctttttgtc
     6061 gattttttta ataaagcctg ttaaaaccct gccagggcca atctcaacaa actgggtgat
     6121 accgttagcc ttcataacct cgatactatc ataaaaacga acaggctcca tgacctgacg
     6181 cgccaataat tctgcaatcc gatccttttc catgacctta gcctctgtat ttccaaccag
     6241 tggcagatca aagtcctgaa attgaatctt gctgagctcc tctgccaacc tttgactagc
     6301 aggcgctaaa agtgctgtat ggaaaggtcc tgagacattc agcggaatta aacgcttcac
     6361 tccctttgct tttaagattt caagtgccgc attgacagcc tcagctgtcc caccaataac
     6421 aatctgtcct ggcgtattat agttagcagg tgacacaaca ccaaccgaag aagcctcttg
     6481 acaagcctcc tcaataagac tagcctctgt attcatcaca gctaccatct taccagagcc
     6541 agcaggcgct gcctcctcca taaagcgtcc ccttttagca actagctcta gggcagtctc
     6601 aaaactcaga acacctgctg caactagggc agaatattct ccaagagaaa gccccgccac
     6661 catatcaggg tgaaccccat aagacgttaa aatacggtaa atagagactg aagcagttaa
     6721 gattgctggc tgcgtgtagg ctgtctggtt caaccgatct tggtcggtat caatgagctt
     6781 gcgtaaatca tagcctaaaa gctgactagc ctgatcaaag gtgtcacgag caatggcatg
     6841 ttggtcatac aaatctcttg tcatgcctag tgtctgagct ccctgaccag caaataaaaa
     6901 ggctgttttt gtcatacttc tccttaatta tatcgtttcg tttttgtcat cagctgcaag
     6961 agcttgccag cgcttagctt cttggctaat cactgctgcc gcgccatagt agatatcctt
     7021 taggatggct tcacagcttt cttctgctct gattaatccc gcaatctgcc ctgccatgac
     7081 agagccattg accacatcac catcaatcac agcgttgcgc agagctcctg ctcccatttc
     7141 ttcgatgtca ctagcagcct tacgatctgc taaaaattct ttttcagcct tagcataagc
     7201 tgatgttagc ttatttttga tagagcgtac cggatggcca acaacttgag ctgaaatgac
     7261 agtatcaata tccttagcct tcaaaatttt atccttaaag ctttggtgag cattagattc
     7321 ctttgccaca acaaatcgag ttccaacctg aacagcctca gcacccagca taaaggctgc
     7381 tgctgcacct cgaccatctg caatcccacc tgctgcaata actggaatag aaacagcatc
     7441 tactacctgc ctaaccaagg tcatcgttgt caatttaccg atatggccac cagcctccat
     7501 tccttcagca ataacagcat caacgcctaa tttttccatg cgcttagcca gggcaacgct
     7561 aggaacaact ggaatcacga taatacctgc ctcatgaagg cgctccatgt atttccctgg
     7621 atttccagcg ccagtggtca ccaccttgac accttcttcg atcaccaaat cgacaatgtc
     7681 atctgcaaag ggagatagca gcatgatatt aaccccaaag ggcttatctg tgatcgcttt
     7741 gacacgatca atatttgcct tgaccacctc tttaggagcg tttcctccac caatgatccc
     7801 aagaccacca gcattggaga cagcacctgc tagatcacca tcagccaccc aggccatacc
     7861 tccctgaaaa atgggataat caatattaag taattctgta atacgtgttt tcataataac
     7921 cttctatgca aagaaatcag gagaataatt tgataatcaa actatcataa taagaagaaa
     7981 gagcgagtta gagcctgaaa gagggtctaa tctcaccctg atggttcgat tattacatat
     8041 caattgacca actaaagcag ttcattaatc agcaggctgg ttaatcagta ttctcgcttg
     8101 tttgagcttt attttgtttt ttcttcaacg taggcaacaa ggtcaccaac tgtgtttaag
     8161 ccttcttctg tttcgatttg aatgtcaaag gcatcttcaa tttctgagat cacttggaaa
     8221 acatcaagtg agtcagcatc taaatcatca aaggtggttt ctagagttac ttcctctgcg
     8281 tccttgccaa gctcctcaac gataatttct tgtacttttt caaatactgc cattttatgt
     8341 ctccttaata taaatattta ttttataaat gtgctaggca catgatataa ctagatttta
     8401 acaattagac tgccccatgt caaacctcca ccgaagcccg acagtaaaat atgctggctg
     8461 ccatctaatt taagctgtcc attctggact gattcagata gtaagatcgg tatactagct
     8521 gcactggtat taccatagtg catcatattt tccagaaatt tctctcttgg cataccaatt
     8581 ttcttagcca tcttatctaa aatacgccga ttggcctgat gtaaaagcag gtagtctaac
     8641 tcctccttgg ccaagcctga ttgctcaata attgctgtaa tgctccttga aacatctcta
     8701 atcgcaaagt caaagatagc acgaccatcc atctgaagaa aggagttgac ctcctgtcct
     8761 tgagaaaatg gtgagcgcag actgctctga cctgatgtca ggctttgacc tcgcgcacca
     8821 tcagtatgta aggcctcagc tagaaaatgc tgctgctcgc tggcctctaa taagactccg
     8881 ccagcaccat ctccaaataa aacagctgtg cttctatcct gccaatcaat aatcttagac
     8941 agggtctctg ctccaataac caagcctctt tgataagccc ctgatgcaat caacttatcc
     9001 gccattgcta aggcaaagac aaagccactg caggccgctg tcatatcaaa agcaaatgca
     9061 ttagtagcac cgatagcagc ctgaaccttt gctgccgtcg atggcatgct agcatctggg
     9121 ctaatcgtag caacgatgat aaaatcaagt gcagtcgcat catatcctga tcttgctaat
     9181 aattgctccg ccactcgagt tgctaaatca ctggtcatct ccacagtgga aatgtgacgc
     9241 ctctcaatcc cagtccgcga cgaaatccat tcgtggctgg tgtccatgat ttgcgacaaa
     9301 tcgtcattac taataacctg cttgggcgta taatgagcca cctgactaat ttttgaaaag
     9361 accattaaac caaatcctcc aaaaactgat gtaaattccc caagccacgc aacagggctt
     9421 gcatttcgtc ctcattcata tcagcgacaa catgaccgac catattttta tgaaacttag
     9481 catgaagacg attcaagaga cgaccctttt tggtcagtga caggtaaacg acccgtctat
     9541 ctacacttga cctcgtcctt tcaatgtagc cctttagctc taacttgttt aagctagtgg
     9601 taaccgttcc tagggtaacc atgagctctc ttgcgatgtc acttggtgtt acctgctgat
     9661 attttccaat aatctcaatt gtatgcatct cctttagaga aacatcatta aactgacttg
     9721 tttttaagct catttcctca ataaccaaaa ttctgttgaa aatatcaact aaatattgat
     9781 taatcttatt atattccaag taaacacctc cctagctgta aaatactttg attttcaaag
     9841 tatatcagac atcaaagtat ttggcaagca cataagagct atttcccctg aaaatttggc
     9901 cgcctcctat ctccataggc cctgacgccc tctttaaagt cctccttaaa ggccaattcc
     9961 tcttgaatgg caagctcttt ttgggcataa tcctcccaac ctgcaaaaaa gctttgccat
    10021 accaaagatt tcatgccggc gtaggaattt gaagagccac gcctcaaacg ctttaacagc
    10081 tgactacagg tcttatcaag cttatctgac tcagcagctc gatagacaaa tccgtactca
    10141 agcccttttt ctgctgtcac cccctcaccg gtcatcacca gatgagtcgc tctatttagg
    10201 ccaacggcac gtgttaacaa gaaaagaccg cctgcatctg gcgctaagcc gacattaaca
    10261 aaggcctgaa taaattttgt ctgggtgcta gcaatacaaa aatccaccgc taaggcaata
    10321 ttaaaggccg caccagccac cgcaccatca gcacagagga taacaggctt tggcaattgc
    10381 ttaatagcaa aggaaatatc ctgaaccagc tcagcaatct tgaccagaga ctggacatca
    10441 tctctttcaa cagcattttg catttcaacc aagtcaccac cgactgaaaa gaccttaccc
    10501 tttgccttaa tcactaaaaa gcgcagagag gggttatcct taaccaacct aatagcctcc
    10561 agaatctcct gacaggctgg aatgttaaag ccattagaca cctctggacg atttaaggtt
    10621 aaaatggcca gatcctcttc aagctcaaaa atgatatttt gaaacgtcat atcactcctc
    10681 ttttctgaca gcttatttga tgaacaaata attttatgac caaataattt gacaatcaaa
    10741 ttaattacta gactatagta cactagaatc agtcgttatg caagaaaaag attgtaaaaa
    10801 atacattaaa attatatacg caatttaaaa agttcagttc caaagccaag cttagatcca
    10861 gcacagccct tatacctcta acaaaaagag cctaagacaa aagtgtccta gactctgaaa
    10921 ctttggcatg tgctatgctc aaccattcta tacaattgtg atcaatcact catagagcat
    10981 gtaaacaaga tctgcttaaa tatcctctag agcatctttg accttatcaa agaagccttt
    11041 tttctttgga gcaattggct tttcaccact agcctctgca aaggccttca aggcttcctt
    11101 ttgagcttca ttgagcttgg taggcgttac aatgtttaca gtcacgtgct ggtctccttg
    11161 acctccgcct cgaagcttgg gagctccttt gcctttcaaa cgaaacacct taccagtttg
    11221 cgttccagcg ggaatagaca tggcaacgtc accatgaacc gttggaatat ctactgtatc
    11281 tcccaaagca gcctgaacaa atgaaatatt caagctgtag taaatagtag agccattgcg
    11341 ctcaaactgt ttacttggaa gcacgtttaa aataacgaac aaatcaccat aaggtccacc
    11401 attaaagcct gcttcaccct gaccctgtag gcggatttgt tggccggttt caacacctgc
    11461 tgggattttt actgaaacct tatgaacctt cttttcatga ccagttccat gacaggtatg
    11521 gcaaggctct ttgatttctt gaccgctgcc atgacagaca tcacaggtca cctgacgacg
    11581 catcatgcca agtggggtct gcgtatcaac attaataacc cctgatccat gacatttacg
    11641 acaggttgta ggacttgttc caggcttagc tcctgagcct gcacaggtac tacaggttga
    11701 ttcacgatga tagctgactt ctttttcagt accaaaaacg gcttcctcaa aagaaaggtt
    11761 taccctatat tgaaggtcat caccctgacg cggagcattg gggttacgca taccaccgcc
    11821 gccaaaaaag cttgagaaaa tatcctcaaa gccaccaaag ccgccgccat caaagccgcc
    11881 aaaaccgcct gcgccaccac caaagccacc gtttgctccg gctgccccat attgatcata
    11941 agctgcacgc ttttgtgagt cgcttagggt ttcataggcc tcctgcactt ccttatattt
    12001 ttgctcagct cccggctctt tattgatgtc tgggtggtat tttttagaca tcttacggta
    12061 agctcgttta atatcatcgg ccgaagcgtc ttttgaaacc ccaagacgat catagtattc
    12121 cgtattattc atttattctt tccttcattg acaaaaacag acggagcgag gcgccccgcc
    12181 tatttgattt ttatttattt agccttgcta tgctattttc tagcaattag gggaggggac
    12241 tatcgcctca gtttctagct ttactgagcg gcctcagctc ctcacagctt atttttcagt
    12301 gaactcacca tctacaacat catcgccact gtttgttgag cctgtatctg ctgcaccttc
    12361 tgcaccagcc tgggcttgtt gtgctgcagc tgcttgctcg tacattttaa cagcaagggc
    12421 ttgtgctttt tcattaagcg cttcaagctt agctttcata tcatcaaggt cgcctgactc
    12481 ttgagccttc ttaagctcat caagagctgc ttgagcagca tcacgctctg tgtcaaagcc
    12541 tttgccttca gtttctttaa tagtcttttc agttgcaaag atagcctggt caacttcatt
    12601 tttaaggtca acctcttcct tacgttttgc atcggcttca gcattggctt cagcgtcttt
    12661 catcatgcgt tcaatctctt cttcagaaag accatcgtta gatttgatga caatgtgttg
    12721 ttctttttga gtacctaggt cttttgcctt aacagaaacg ataccgtttt tgtcgatgtc
    12781 aaaggttact tcgatttgtg ggataccacg aggggctgca ggaatgtctg tcaattggaa
    12841 acgtccaagt gttttgttat ctgccgccat tgggcgttca ccctgaagca cgtggatatc
    12901 aacagctggc tggttgtctg ctgcagttga gaagacctgt gatttagagg ttggaattgt
    12961 tgtgttgcgg tcaataagct ttgtaaagac gccacccatt gtttcgatac caagtgacaa
    13021 tggtgtcacg tcaagaagaa caacgtcttt aacatcacca gtgatcacac caccttggat
    13081 agcagcaccc atcgctacaa cttcatcagg gttcactgat ttgtttggct ctttgccagt
    13141 ttcagcctta acagcttcaa ccacagctgg gatacgagtt gaaccaccaa caaggataac
    13201 ctcatcgatt tctgacaagc tcaagcctgc atcagacagc gcttggcgaa caggaacctt
    13261 cgtacgctct actaaatcac gagtcaggtc atcaaatttt gcacgagaca ggctcatttc
    13321 caagtgaaga ggaccagcag cgccagcagt gatgaatggc aatgaaattt gagtttgagt
    13381 gacacctgaa agatcttttt tagctttttc agcagcgtcc ttcaagcgtt gaagagccat
    13441 tttatcttgt gataggtcga ttccgttttc tttcttgaat tctgctacta agaaatcaat
    13501 gattttttgg tcaaagtcgt caccaccgag cttgttgtca ccagcagttg caagcacatc
    13561 aaagacacca tcacccaatt caaggataga cacgtcaaag gtaccaccac caaggtcaaa
    13621 gactaagatc ttttcttctt tatctgtctt gtcaagaccg taagcaagag ctgctgcagt
    13681 tggttcgttg acgatacgtt ctacctcaag cccagcaatc ttacctgcgt ccttagtagc
    13741 ttgacgttgt gcatcgttga agtaggcagg aactgtgata acagcctttg ttaccttttc
    13801 accaaggtag tcctctgcat agcctttaag gtattgaaga atcattgctg agatttcttg
    13861 tggtgtgtat tctttaccat tagcagcaac cttttcagag gttcccattt ttgatttgat
    13921 tgagataaca gtatcaggat ttgtcactgc ttgacgctta gcggcgtcac caacgatgat
    13981 ttcaccgttt ttgaatgata ctactgaagg cgttgtgcgg ttgccttctg ggttggcaat
    14041 gattttgctt tctgttcctt caagaactgc tactgctgag tttgttgttc ctaagtcaat
    14101 accaataatt ttagacataa tattttttcc tcttttatat atttatgata ctcctcttat
    14161 gtagcaccga cgctagcagc ttcctatgga atctcatagc tgaaatttga gcctaaagtc
    14221 tcaaattttc cgagtcataa aacattaatg ttttatgaat tttgccacgg cgaagagtat
    14281 cggtaatgct cacttcgttc gcttttgcta gcgaaaaaag cagcaatctt atttcttgtt
    14341 ttcatagttt actgtcattt cggacatgat tcattttatt gattagctat catcacggga
    14401 taattgcgac gtgagatagc aaaatcgata ccattttgct atcgaactag taaggagtct
    14461 aggcaagccg ccacagctgt tgccgtctaa tgatgagcca tttcaatggc catcattagt
    14521 gactagttgt acacaaccac catcgctggt cttagtaagc gctcatgaag cttatagcct
    14581 ttttggaaaa cctgagcgat actatctgct gggtggtcat catctgctgg tagggtttgg
    14641 actgccatgt gcagattgtg gtcaaaggct tccacaggaa cctcttcaat accttcttct
    14701 ttaagggctt gaacaaggct ttcttgcacc atttctaggc cttttttgac atcatctgtc
    14761 agaccctcaa cagccaaagc acgctccaag ttatctaagc ttggaaggat ttttttagct
    14821 aaatcctgtg aacgatagcg ctgcaagctt tggcgttctt cattcgcacg acgctgaata
    14881 ttttgcattt ctgcgtgagc tctgaggtat ttattttcaa aatcctctgc tcgctggaga
    14941 gccaactcta gctcagatgg ttcctcggct gcttcatcag caacagtatc agctgattga
    15001 tcagcctctt caactggctc tactgcttcc tcagcagcct catcaagaat gtcctcttga
    15061 tccttgagct cttcttttgg ttttttagac aaggtgtcta cccctttctt acattttctt
    15121 aaatcatatt aaggccttag tgaacctcat aatggttgct gtttaagtaa cggtaataat
    15181 ctcttaactt cacagccagc agctgaccaa tcacattaat caagctaacg ctacggcgat
    15241 aatccatatc aaccggccca attaagctta acaagccaaa tcctctgtat ggaattaaaa
    15301 acttgtaggt cagcaaggtc acgtttgcta gggctggctc actgctgtca gcaacctgaa
    15361 ccgttaccat ctcttcctct gatagactct gtctgatgga tagggctaag cgctgctcct
    15421 catcaagaaa ccgataggtc gcaaggccag cataatcaag agcagcaacc ttgccagaga
    15481 caaaaatcgt ttctcgaaaa agcccaacaa agatatagtc aaacaaatcc aaaacattgt
    15541 ccgtcaccgt aaaatacttc tgaacaatct gagggatttc tgttcgtagc ttgtaatgaa
    15601 cagtcatgac atctttgcca agtaagcgat cagcaacaat gaccttaagc accagcaaat
    15661 cacgattcat aaaattctta ggaatagcaa actgtacggt caacggcttg gactcatcta
    15721 aggtcaaaac agctaaggca tcatgactag atagctgaac aatatcaaag cctgtcagtc
    15781 tttgccttgc aggctcgaca tctaaaatcg ctgccgtata gccggtcata tccgataaca
    15841 tctggctagc ccttagcaaa acgtcctcta gcttaaaggc ctcaaaatca aaggccttga
    15901 ccagctgata aaaatcctgc tcatcaatgc tgccaaggtt aagagaatgc tctacaaaat
    15961 atttaaagcc tgccgcactt ggcatacgtc cacttgatgt gtgagccttc tccagcaatc
    16021 ctagtttttc aagctttgcc atgtcatttc taatagtggc actactagaa gcaataactg
    16081 actgcaaagc cttagagcca accggttcat gggtctgtgt aaataaatct acaataagat
    16141 tcaagatgtt agattgtctc tctgtgatca caaaccaatc actccctttc tgttagcact
    16201 ctatacatcg gactgctaat ttatagttct attatatcct tttaaaacag catgtcaaga
    16261 aaaaaactca aaaaattagc actctttttt tagagtgcta attccgtata agacattgac
    16321 agtatcacct ttgaaatcat gatttaaagg agcaatagaa agccacttac tatctctcag
    16381 actggtatta gattcacctt actcgctaaa aagagcgctg ggcagtaaaa ggcgattagc
    16441 ttagctgctt gaagccttaa ggcctaacaa tcaagccttc agtagagcag gatagggctt
    16501 ggctgcgtaa tcacagctcc cactcctaag gcttacgcct gcaagctgac acaaagctgc
    16561 agtacctgct aaagcaaata tctgggctta ccggttgttt cagtgtcttt ttcgtctcct
    16621 caatcatcat agcttgtcaa gcctcttgct tcaatcagct gcacaagcct ttgggcatag
    16681 cccttgtcat cagaataacg ataggtctgc aagctcttgg ccggtctttt gtagcctttt
    16741 tcggttgcta ggctttgata aagcttttta tctccacctg tgccttgact caaccatgac
    16801 aagtaggctc tgatcgaatc ctctctatcc cgatagatag catagactgt cttgtgcttt
    16861 gaggttgcct gcttcttgag gctaatggaa gcctgccctg gagctggctg cagtgaaaaa
    16921 aggttatgat atttggccgc caacagggtt ctgccataat tggtttctaa gataatctga
    16981 ccaatcaaaa tagaaggacg aataccatag tttttggcta aaggcttgac ttccttggca
    17041 acgagctgga taaattgccc ctctgtataa ggaacagaca tctcctgact ggctgatgtg
    17101 cctttggcat tgaacagcaa gggaccaatc aaagctacca taatgaacac taaaaacact
    17161 agaaaatagg aaaatttaag tcgtcttctc attttttctc cttcaatcgt gttaggtatt
    17221 cttctaggct gaggctatga gcggtaatgt attgggcaga ggccttacca acatatcgat
    17281 aatgccagtc ttcatactca atccctgtgc tcgtctgctt gccttttgga tagcgcaaaa
    17341 taaaaccaaa ttgtggagct attttttgaa tctcctgtgc caccttaggg tcactagcat
    17401 ttaggctatc tactgtactc atatcaatag ctagaccggt ctgatgctca ctagtgcctg
    17461 ctggctgggc atatttccga accaaggctt cagctgcctc ttgggtcagg ctaggatcat
    17521 ttgccagctc ttgggcaata taagactgat aaagctcttc ttgctggaca accgaacgat
    17581 aaccagcaat caagcgctcc tgaggttcaa tcgtctgcgc cgctgctaga aaatcagccg
    17641 tctcctgctc aatgcgctta tcaataggaa tcccgttaat ctcaaccaac tcaggactca
    17701 tttcctcttg agggtgatcg cgattgacga ggaccagctg ccagtccgta gctgatacct
    17761 ttggcagatc agtagtcttt ttagcctgct tagctgcctt tggggcaggt gctgtttgat
    17821 tggccttggg gcctacagcc tgtttttcag gcttgataaa aagataaatc cctgataaaa
    17881 acaacaggac gaccaaggcc tgtaaaagga ctcttatagt gttattcttc atctcttatt
    17941 gactcaatta tctcacgacc acgatagcgg tagctcatat ctccaatagt tttgatggta
    18001 aactgcccat tctcatattc cacaacagtg acgcttccat tgtcaatgta ttgcttttcc
    18061 ctatctgggt caattagcca catgaaggta ccgatggtca tgccatgact aaccacgata
    18121 gcattgccac ctcctgcatt ttcaacagca agcgcgatag cctcaaagcc ctcatagata
    18181 cgcttgctca atacctccca gggctctgcc cagttagcag tatcaacctc gacaatactc
    18241 tctgctaatt ctgaataagg cacatcacgc agattgtcac gattttcaaa ggcctttgtt
    18301 ctaggaagaa cacctaaaaa cagctcagaa tcataagccc catccaggct accaaagcac
    18361 cactcacgaa tccgcttatc tctagtgtag ggtaaaaact cattgtcaga ctctcgtaga
    18421 ataatctcca ttgtctgcat ggtacgacct gaatcactcg aaaaagcagc cttgaatgga
    18481 ataccagcag ccttcaaacc aagtcccaat tcacgaatcc cttcttctcc tgcctttgtc
    18541 aagggggtat cactccagcc ctgtgcacga ccaatggtat tgaacatcgt cttgccatgt
    18601 ctggcaatgt ataatcttgt ttttgtcata atgaacctcc aaagtctctc tgctattata
    18661 gcattaaaag aaaacacttg caaaaccatg caagtgctag ccgttaattc ttaaagctat
    18721 ggataggggc aggcatttgc ccaccacgag caataaagtc agccgatgaa tgcggattaa
    18781 cagccataac cggagctgtc cctaaaagac caccaaaagc aatcatatca ccctccttac
    18841 cctttggaat aatacggacc gctgttgtct tttgattaat cacaccgata gctgcctcat
    18901 cagcaatcat ggctgcaatg gtttcagacg gtgtctcctc tgggatcgca atcatatcca
    18961 agccaaccga gcaaatggca gtcatggctt ctagcttttc aagattaagc gagccaccct
    19021 gaactgctgc aatcatgccc tcgtcctctg atacagggat aaaggcgcct gacaggccgc
    19081 ccactcggtt gcaagccatg acaccaccct ttttgactgc gtcattaagc aaggctagag
    19141 cagcagttgt gccatgtgta ccaaccattt caagtcccat ctcctctaag acacgtgcca
    19201 cagagtcacc aactgctgga gtgggagcta gcgacagatc cacaacacca aagcccacac
    19261 ctagccgctc acttgccatc tgtcccacta gctgaccgat acgcgtgatt ttaaaggccg
    19321 tttttttgac tgtctcggct agaacgtcaa agctttcacc acgaaccttt tccaaggctc
    19381 ttttgaccac accaggtcct gaaacaccaa cgttaatcac cgtatccgcc tcaccgacac
    19441 catgaaaggc tcctgccata aaaggattgt cctcaacagc attagcaaag actactagct
    19501 ttgctgcccc catttcagaa gccttggcgg tttccttgat gatacgcccc atatctgcaa
    19561 ctgctgtcat attaatacca gaccttgttg atccaacatt aaccgaagcg cagaccttct
    19621 gtgtttgagc caaagcctga ggaatagact caatcaaaat cttatcaccc ttttgatagc
    19681 ctttttgcac aagagctgaa aagccaccga taaagtcaac tccgatatca caggcagcct
    19741 gatccagagc ttttgcaagc ggcaggtagt cttctgcgtc tgttgccgcc ccaataaggg
    19801 ctatcggagt tacagagaca cgcttattaa caatgggaat acctagttct gctgcaatgt
    19861 catcaccaat cgccacaaga ttggctgcct ttgtcgtaat cttttggtaa atcttagcgg
    19921 cagctctatc aatatccgaa tcaatacaat ccagcaagga aatccccatc gtaatggtac
    19981 gaatatcaaa atgctgctcc tcaatcatct caactgtttc acgaacctgt ctaatatcca
    20041 tagtcatcaa gctccttata tgttatgcat agcatcaaaa atcgctgcgc tttgaatatt
    20101 aatcgtcacc tgcaattgct ttccataagc ctgaagcacc tcacgcagat gagcaaaatc
    20161 ctgcttttca ctgcttgaga caatggccat catggtaaaa taatcatcta aaacggtctg
    20221 tgaaatgtca tcaatattta atcctaatgc agcaatttgt cctgaaacac ctgcgacaat
    20281 cccttgattg tccttaccaa caactgtaat gatagctttc atggcacacc tcctcaatat
    20341 gtgttatatt ttatcacaaa caaaaagaga aagctatcag agataagagg tctggtagcc
    20401 ccttgcaaaa atagaacaat gggtaccaga aaaaagagtt tgttatccaa ttgataccgt
    20461 ttattaatat ttagacttta taatataata gcagctaata aaagataaga cgtttgaagc
    20521 tgccaaaaaa gctgggctcc cttaggccca gtttttttgt aggttaatta agggatagca
    20581 gaagattagt cgggattgta agaatagccg tatcctctct taccatctct atcagctaga
    20641 ccatctaaat agccatttcc ataattatca ttataccctt gactatagtc attatattcc
    20701 tttggactag actcatcaaa ccgcttagga taatctcctt tgtgcttttt gccaccatat
    20761 ccatcctcat agccaactcg gtaaccatca cgacgaccat gattgtaggg gtgttcgtct
    20821 ttaagttttg gtgattcatc attttctccg cttaagcctt taccgtctaa atcttccttt
    20881 ggcttattct ctccatctaa tccttttaaa ggatttttac gattatttcc ttctaaattc
    20941 ggagttgatg ggggaccagc ctcacctcgt tcaccttgct ctggttcctt ctgattctcg
    21001 ccattcaagc ctggaagcga aggacggcct tgattattac cactcaaccc tgaaagtggg
    21061 ggaccggctt cacctcgttc accttgctcg ggttccttct gattttcacc attcaagcct
    21121 ttttctggca gctttggact attgccctga ggctttggtt gaggctgcgg gctagaatta
    21181 tccttaccta gatctaagtg ctgtggcttt ccttgtggct gatggtgatg acctgaacca
    21241 gagctgttac ctcctctcag ccccagtggc tgggaaggcc cttgattagg actagcctga
    21301 ggctctgagg cctgtccact actatttcct tggctgttca cactgagaga ctgaggttga
    21361 ttcccatgat gacctgagct ctttgctgtc ggctgggacg ggctagtagc ctgatgctga
    21421 tgattagtag gctgatctga aggcttaggc tgcaagttat cctttttcgg tggccgactg
    21481 accattgaat ctgatgagct cttgtgcgac ttatcgtcat ctccaatcga gctgactggc
    21541 tgctcctttg gcctcgcttg atgggatgag ccaccaagac ttcctaataa acctccaaag
    21601 acaagtgcag ctcccagcag caagctggtc accactgcac cggcaaatag ccattgtttt
    21661 ttggacttcc atgtgcgaaa acgtccttct gtttttctca tactttttta actctctcca
    21721 tattttttgg taaaaatacc aagaaatag
//
LOCUS       DARYSY010000038        20321 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYSY010000038 DARYSY010000000
VERSION     DARYSY010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20321
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            18..98
                     /locus_tag="TVR04_001336"
     tRNA            18..98
                     /locus_tag="TVR04_001336"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TVR04_001337"
     tRNA            105..175
                     /locus_tag="TVR04_001337"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TVR04_001338"
     tRNA            187..259
                     /locus_tag="TVR04_001338"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TVR04_001339"
     tRNA            268..339
                     /locus_tag="TVR04_001339"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TVR04_001340"
     tRNA            358..441
                     /locus_tag="TVR04_001340"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(536..1732)
                     /locus_tag="TVR04_001341"
     CDS             complement(536..1732)
                     /locus_tag="TVR04_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1270026.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYILETTNSAWYV
                     GVLNFLIFIPNTFSFIFGKKIDSHPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIILTCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFIDIVTFLGSILFFRRIEFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFAGLNVYQLLIAREVGNSAFYGLLVSASAIGTLVGTTLGANLVLQR
                     LSVGKAFWLATALFGTGIGFTALFRNSFSLLLIWFLSCLFLGITHVTQKPILQTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLIFGFLANFLSWRLFVVLFAFSFILVSLLYFSNKTL
                     RQYDIS"
     gene            2294..3013
                     /locus_tag="TVR04_001342"
     CDS             2294..3013
                     /locus_tag="TVR04_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270027.1"
                     /translation="MRSKKTSIRLVQKYGICSAVVALATIASLGTAGAVHAEAPEYPK
                     TTEFSMGVQPYSVFRKGFETYAEKLKKHLEYRLTEFQKRQEELEERGQQSSGKPGPVG
                     PKGQTGDAGPRGPVGPKGEKGEDGRDGQPGPKGPIGPKGQTGDQGQKGERGDQRPNSD
                     QEKGSKPSAPKAPEKAPAPKAPRALEKSAHTKKSVSSAQKGILPATGETNHPFFTLAA
                     LSIIASAGRLALKEKKNKISY"
     gene            3140..4510
                     /locus_tag="TVR04_001343"
     CDS             3140..4510
                     /locus_tag="TVR04_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270028.1"
                     /translation="MTNKVNHHKVVRRSGLCSVVLALAVTVGLGTDREAKADVGVPSY
                     PNTNVFKGAHWTVLDEKLADYHQELEEYLSFKFNVLSSRMNGLDKKIKENAERPGPPG
                     PAGPKGDTGPIGPVGPTGPKGDKGKDGQDGKPGLPGAQGPKGDTGPIGPKGDKGDPGL
                     KGDKGAPGPKGDTGPIGPKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEPGLKGDK
                     GEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQG
                     LKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGDKGEQGLKGD
                     KGEQGLKGDKGEQGLKGDKGEQGQRGEKGEQKPKGDQGKDIKSSAPKAPEQSPAPQAP
                     KSLEQQSASPKVPAPKSAPSKSAAPTSKKAVLPATGEASHPFFSLAALSVIASAGLLT
                     LKRKNN"
     gene            5020..5544
                     /locus_tag="TVR04_001344"
     CDS             5020..5544
                     /locus_tag="TVR04_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1270029.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLALDLAGVRPHFSI
                     TFDNGFDDTFLVLQAVDVTKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            5758..6609
                     /locus_tag="TVR04_001345"
     CDS             5758..6609
                     /locus_tag="TVR04_001345"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1270030.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            6679..7122
                     /locus_tag="TVR04_001346"
     CDS             6679..7122
                     /locus_tag="TVR04_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1270031.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQKMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITVFSEELEG"
     gene            7126..7845
                     /locus_tag="TVR04_001347"
     CDS             7126..7845
                     /locus_tag="TVR04_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1270032.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVIIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            7838..8647
                     /locus_tag="TVR04_001348"
     CDS             7838..8647
                     /locus_tag="TVR04_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1270033.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGISPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(8828..10084)
                     /locus_tag="TVR04_001349"
     CDS             complement(8828..10084)
                     /locus_tag="TVR04_001349"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1270034.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEVAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            10189..12489
                     /locus_tag="TVR04_001350"
     CDS             10189..12489
                     /locus_tag="TVR04_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1270035.1"
                     /translation="MVKWKKNQISKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VASDAISDNIKKAIVSTEDDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKSETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAHNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            12752..16318
                     /gene="rpoB"
                     /locus_tag="TVR04_001351"
     CDS             12752..16318
                     /gene="rpoB"
                     /locus_tag="TVR04_001351"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1270036.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGSEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQEIAESTEDN"
     gene            16409..20044
                     /gene="rpoC"
                     /locus_tag="TVR04_001352"
     CDS             16409..20044
                     /gene="rpoC"
                     /locus_tag="TVR04_001352"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1270037.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLATEIAELKEELKTATGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQNIQEVIDSLPLNVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGLGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEGAEATE
                     EPAIIEE"
     gene            complement(20136..20321)
                     /locus_tag="TVR04_001353"
                     /pseudo
     CDS             complement(20136..20321)
                     /locus_tag="TVR04_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057303.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5732 a         3891 c         4971 g         5727 t
ORIGIN      
        1 gtaatttaat atattttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 agtatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat atttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtcctcac ggacgtgccg
      421 gttcgacccc ggccgccggt atagcttaaa gtaaaagaaa agacaaggtt tcttagcctt
      481 gtcttttctt ttatactttt actgcccttg ttttgggaca cattgttaac tatacttagg
      541 aaatatcgta ttgtcttagc gtcttgtttg agaaataaag cagactaact aagataaagg
      601 aaaatgcaaa taggacaaca aagagacgcc atgacaggaa gttggctaga aaaccaaaaa
      661 ttagcgaacc cagggcaagt gttgggatgg ttacggtata aaaagcactg aaaacttcac
      721 caagatgctc atcaggaatc tcagtttgta aaataggttt ttgggtaaca tgcgttattc
      781 caagaaataa acaggaaaga aaccaaataa gcaataaact aaagctgttc cggaataatg
      841 ctgtaaagcc aataccagtt ccaaaaagag cagttgctag ccaaaaggct ttccctacac
      901 ttagcctttg taacacaaga ttagcaccaa gtgtcgttcc tactagggtt ccaatagcgc
      961 ttgcagatac taagaggcca taaaaagctg aattccctac ctctcttgct attaataact
     1021 gatagacatt taagccggca aaaaggaaat tagcgatagc acctcccaat gtgatggcta
     1081 acaccacttt attgtgccag ataaagcgca agccacttaa aaagtctgtt cgttcatttg
     1141 tttgttcaat tatttcttta aattctattc tcctaaaaaa taggattgaa cctaagaagg
     1201 taacgatatc aatgaaaagc aaaggaatgt agctgatcac agaaagcaaa aagccactaa
     1261 tggcagtaaa aacataatct gttccattgt aagccactga catatacatt tctgctttag
     1321 ctaaatcttt agtaggaatg agtttaggta caagagcatc ttgaacagta taggtattca
     1381 acccaaccat agaagccaga aagacacaag ttaaaataat ggttaagcta agacttgcat
     1441 gtatctccct taaagacatt cctaaaataa tccccaaaac agccaataat tgggcccact
     1501 ccagaatcac tagcaggttc ttcttagggt gcgaatcaat cttttttcca aagataaagg
     1561 agaaggtgtt tggaataaaa atgagaaagt tcaatactcc aacataccaa gcactattag
     1621 tggtttctag tatataccaa gacagcacta gggtgtaaat cgagtcaccg caattgctaa
     1681 tcagtcgccc caaaaataac cggcaaaaat cattatattt ccttaatatc atattgtatc
     1741 ctttgataaa gagattgaac atcttttata tttatagtat caataaatga taaaaaatta
     1801 ctgaatgata gctgtgtttg atgttcgcaa cattttaaaa tatctttgca aaaatcatac
     1861 ctagacacat acaatcccac ataagtttta aaagcattca attgcctttt aagatcttta
     1921 tgagtcatgt ttgtaaagat atcctcttgc aacagatctc ttaatctcta attgtatcca
     1981 ataagaagca gctttgtcaa tacggaagcc gaatagtctt tttgcctttc cttgtcagct
     2041 gggcaatcat gagggctttg tgctttgatc ttttgcatct ataaggaggg tgaatctatt
     2101 gatgaggtgt tatcggtagt ggggcctact gatgtcagac aattgcccct ttgattagaa
     2161 aaaaaaaaaa aacgaaacta cggaagcgaa atctccaaaa catattcaca gcctacaagc
     2221 gtcatgttaa gattttcttt ggaataaaaa agattagaaa tcattaacgt ttctaaacta
     2281 aaaggagaga aacatgagaa gtaagaaaac aagtatcagg cttgttcaga agtacggtat
     2341 ctgctcagca gttgtcgccc tagcaaccat tgctagctta gggactgctg gtgctgttca
     2401 tgctgaggct ccagaatatc ctaagactac ggagttttct atgggagttc agccttatag
     2461 tgtctttcgg aaaggctttg aaacatatgc agagaaattg aagaaacatc tggagtatag
     2521 actaacagaa tttcagaaaa gacaagaaga actagaagag cgtgggcagc aaagctctgg
     2581 aaagcctggt ccagtgggtc cgaaaggaca gacaggtgat gctggtccta gaggtccggt
     2641 tggtcctaaa ggagagaagg gtgaagacgg aagagatggt cagcctggtc ctaaaggacc
     2701 aattggtccg aagggacaga caggcgatca aggccagaaa ggcgagcgtg gcgatcaacg
     2761 accaaatagc gaccaagaaa aaggtagtaa gccatcagct ccaaaggcac ctgagaaagc
     2821 tcctgcacca aaagcaccaa gggctttaga gaagtcagct catactaaga agtcagtgtc
     2881 ctcagctcaa aagggtatat taccagctac aggagagaca aatcacccat tcttcaccct
     2941 tgcagcgctc agcatcatcg ctagcgctgg taggctagca ttaaaggaaa agaaaaataa
     3001 aattagctat taaaatgttt tttgtagcta ttggttgcta gtgttatcag tagatgactg
     3061 ctggctctgg tgtcaattta aaaattggtg ccagctcatg ataataaaat tacctagctg
     3121 ataagataaa ggagataaca tgacaaataa ggtaaatcat cataaagtag ttcgtaggtc
     3181 tggtctttgc tcagtggtgc tagctttggc agtgactgtt ggcttgggaa cagataggga
     3241 ggctaaagca gatgtaggag tacctagtta tccaaatact aatgtattta aaggagctca
     3301 ttggacagtt ttagatgaaa agcttgcaga ttaccatcaa gaattggaag agtatttaag
     3361 ttttaaattt aatgtgctta gttctcgaat gaatggttta gacaaaaaaa ttaaagaaaa
     3421 tgcggagaga ccgggccctc caggtccagc gggtccaaag ggagatactg gtcctattgg
     3481 tcctgtaggt cctaccggcc caaaggggga taaaggtaag gatggccagg atggtaagcc
     3541 aggtcttcct ggtgcccaag gtcccaaagg tgacaccggt ccgattggac ctaaaggaga
     3601 caagggcgat ccaggtctca aaggagataa aggtgcccca ggtcccaaag gtgacaccgg
     3661 tccgattgga cctaaaggag acaagggtga gcaaggtctg aaaggggata aaggtgagca
     3721 aggtctgaaa ggcgataaag gtgaacaagg tctcaaaggg gataaaggcg agccaggtct
     3781 caaaggggat aaaggtgaac aaggtctcaa aggggataaa ggcgagcaag gtctgaaagg
     3841 cgataaaggt gaacaaggtc ttaaaggaga caaaggtgag caaggtctta aaggcgataa
     3901 aggtgagcag ggtcttaaag gagacaaagg tgagcaaggt cttaaaggcg ataaaggtga
     3961 gcagggtctt aaaggagata aaggtgagca aggtctgaaa ggcgacaaag gcgagcaggg
     4021 tcttaaagga gacaaaggtg agcaaggtct taaaggcgat aaaggtgagc agggtcttaa
     4081 aggagacaaa ggcgagcaag gtcttaaagg cgataaaggt gagcagggtc ttaaaggaga
     4141 caaaggtgag caaggtctta aaggcgataa aggtgagcag ggtcttaaag gagacaaagg
     4201 tgagcaaggt caacgcggtg aaaaaggtga gcaaaaacca aagggtgatc aaggaaaaga
     4261 tatcaaatca tcagctccaa aggcaccgga gcaatctcct gctccacagg caccaaaatc
     4321 tttagagcag cagtcagcta gtcctaaggt accagcgcct aagtcagcac caagcaaatc
     4381 agcggctcca acaagcaaaa aagcagtcct accagccaca ggagaagcaa gccatccatt
     4441 ctttagcctg gcagctctta gcgtcatcgc tagcgcaggc ctgctaactc taaaaagaaa
     4501 aaacaactaa attagctttt gcaactttct cctactaaat gatagccttt agcttgaagg
     4561 tgattgatta gtttaaaagc tgatatgagc actagagagg ccctaatggg gtctcttttt
     4621 gcttgcagca gtagatattt tgtcttcctc tttcatgggg tgatgtagtt ggtgtgcttt
     4681 ttggttgagc tgttttcatc agagccttta agggtctgtg taactaagat gatgaggcaa
     4741 gtcagctgtg tgtatcacca tatcgttaac tgagtaagac gcttggagat cttaactact
     4801 agtttgttag cgtggtgagc tttttgatac gtttcgggaa aacagatctt tttgtccatt
     4861 ttctgtgcga ggcattttaa ggcagggaat tgtagaaaaa aagaattaag acaggttggt
     4921 aattgttgtt ttgtctggat ctggttgttt tggatatgct tattgtgata tgattaatat
     4981 actggatctg gtaatagctg tatcaggagg tgtgtttgta tggttgagta ttgggacatt
     5041 tatacgatga atcgtcttaa gactggtaga ctcatggagc gtggagctgc ttttgtagag
     5101 ggtgcttatc atttagtggt tcacgcctgt gtctttaatg acaagggaga aatgctgatt
     5161 cagcagcggc aaaaggataa agagggttgg cccagctatt gggatataac ggtaggcggc
     5221 agcgctcttg caggtgagac gtcacaagag gcagtgatga gagagctgaa ggaggagcta
     5281 ggacttgctc ttgatttggc tggtgtaagg cctcattttt caattacctt tgataatggc
     5341 tttgacgata cttttttggt tttgcaggct gttgatgtaa cgaagctagt tcttcagaca
     5401 gaggaggtac aggctgttcg atgggctagt cgtgatgaga ttttagccat gattgatgct
     5461 ggtattttta ttccctactt taagagcaag attgatatgt gctttgagtt agtggggcaa
     5521 tatggagcga tcaagtggtc atagagactg ctgctgtctt agctttgctt gctatgctag
     5581 tggttgctgt ttttggttgc tgatctggta aagcctcacg ctagtaggga caagtggttg
     5641 gctattttga tacaaacacg ctgtctatgc atcattagat actaactgta tttatttgaa
     5701 tttttcatga agattgtgta tatttgatac tataatgaca tcaaataaag gagtattatg
     5761 actgcaatca ttgagagagc tcctgcaaaa ataaatctag gcttagatat tcaaggcaag
     5821 cgaccagatg gctatcatga cctgtctatg gttctagtta gtgtagatct ttgtgattat
     5881 attacagtgg atcatttaga ggaggatagg attttattga cctctaattg ccctagattg
     5941 cctattaatg agcacaatga cgtttacaag gcggcttatt tgctgaaaga gcgatttcaa
     6001 atctcaacag gtgtctctat tttcttggat aagagggtac ctgtttgtgc tggtatggga
     6061 ggtggctcaa gtgatgcggc tgcagcaatc agagcattga atcagctgtg gcagctaaag
     6121 cttagtcccc gtcagatgat tgacattggc atgcagattg gtagcgatgt gccttattgt
     6181 ctttttgcag gctgcgccca agtgactggc aaaggcgagg tggttaagcc aatcaatggc
     6241 cgcttgtcct cttgggtggt tctagtgaag ccagaatttg gcatttctac tagaacgatt
     6301 ttttgggata ttgattgtga gacgatatct cgagtgccga ttgaggatct ggtttcagcc
     6361 attgaggcag gtgattatca gcgcttgctt gcaacgatgg gaaattcctt agaggatatt
     6421 tccattgcta aacggccgtt tattcaaaag gttaaggata aaatgctgca gtcaggagca
     6481 gacattgccc tgatgacagg aagtggtcca acggtatttg ccctatgtca aacagaaaaa
     6541 caggccaatc gtgtggtgaa tagcctgaag ggtttttgta aggaggtcta caaggttaga
     6601 acactgtaga tcagccttga agttgcgtct tttggggcgt catgctataa ttaactggtt
     6661 aatgaggaga gggaaatcat gacaatttta gaaaaaaagc ttgataattt ggttaatcgt
     6721 attttgttaa aggctgaaaa tcagcatgag ctgctctttg gtgcttgtca gagtgatgtc
     6781 aaattaacaa atactcaaga gcatattttg atgcttttgt cacaggaaaa gctaaccaat
     6841 acagatttgg caaaaaggct aaatatcagt caagcagcag taactaaagc gattaaaggc
     6901 ttgatcaagc aaaagatgct agcaggaaca aaggataccg ttgatgctcg agtaacctat
     6961 tttgaactga ctgatctagc aaggccaatc gctaaggagc atacacatca tcacgataaa
     7021 acactagctg tttatcatcg tttgttggca catttttctg cggaggagca ggtgattgtt
     7081 gaaaaattta tcactgtttt ttcagaggaa ttagaagggt aattaatgag atacatatcg
     7141 gtggaaaatc tctcattcca gtatgacagt gagcctgttt tagagggaat tagctatcat
     7201 ttggatagtg gagagtttgt cacattgact ggtgaaaatg gcgctgccaa gtcaacccta
     7261 atcaaggcga ccttggggat tttaaagcca agggctgggc aggtgattat agctaaacag
     7321 aacattcatg ggaaaaagct gagaattgcc tacttgccac agcaggttgc cagctttaat
     7381 gcaggctttc cgtcgactgt ttatgagttt gtcaaatcag gcaggtatcc tagaagtggc
     7441 tggtttacca gactaagtaa gcatgatgaa gagcatgttc ggacgagctt ggagtctgtt
     7501 ggtatgtggg atagtcggca taagagaata ggaagtttat caggtggtca aaagcagcgt
     7561 gtggttattg cgcgtatgtt tgcttctgac cccgatattt ttgtgcttga tgagccgacc
     7621 acaggaatgg atagtggaac aacagacact ttttatgagt tgatgcacca cagcgctcat
     7681 agacatggta aggctgtttt gatgattacg catgacccag aggaggtcaa ggcttatgct
     7741 gatcgaaata ttcatttgat tagaaatcag cggcttcctt ggcgctgctt caacattcat
     7801 gatgctgagg ctgatgagag taaaggaggg tcattccatg cttgagattt tatcttatga
     7861 ttttatgcag cgtgctgtta tggctgttgt agcgatcagt atctttgctc cgattttggg
     7921 tatctttttg attttgcgtc gtcaaagctt gttgagtgat acgcttagcc acgtttctct
     7981 ggctggtgtg gcctttggtg ttgttcttgg catttcgcca accttcacaa cgattattgt
     8041 ggtggtgcta gctgccatct tgctagaata tcttagggtg gtttataagc actatatgga
     8101 gatttcgaca gctatcctaa tgtccttggg gctggctatt tccttgatta tcatgagtaa
     8161 gtccactagc tcttctagta tgagcttgga gcaatacctt tttggctcta tcattactat
     8221 tagtacggag caggttgctg ccttatttgt cattgctttg attattttag ccttgacgat
     8281 attatttatt cgtccaatgt atatcttgac cttcgatgag gacacagcct atgtcgatgg
     8341 cttgccagtg cgtgtcatgt ctgttttgtt taatattgtg acaggtgttg ctattgctct
     8401 aacgatccca gcggcaggag cccttttggt atcaacgatt atggttttgc cagcaagtat
     8461 tgccatgcgg cttggtaaga attttaaatc ggttattttt cttgggatta tgattggctt
     8521 tacaggtatg ctgtctggta ttttcttgtc ctatttttgg gaaacgccgg caagtgcgac
     8581 cattacgatg atttttattg cgatcttcct tgtggttaac ctgctgtcct ttatacgtca
     8641 aaaataatca tccaaagcaa gattttccta gctgtcagat aaacacttct gttcgctctg
     8701 ccttttctag aatagctact tggagaaagg ctctaatcaa tactaaaacc gtatgatatc
     8761 gagccttgca gcatatgata tcatacggtt tttaataggt tatattagtc tttctagctg
     8821 tctgtgatta gtaggttagt acagcgtatt ttttcttgcc gcggcgaatg acggtcaact
     8881 gattgtcaat gcgatctgct gtagataagc tgtaatccag atcctgaagt cgttctccat
     8941 tgaggtagat cgcgccattt tgtaaatcct cacgcgcctg acgttttgat ggtgaaatgc
     9001 ctgctgtgac taacatatcc acgatattta ggctgtcttc tgcttgaacc tgatagttag
     9061 ggacattgct taagccttgc ttaagctcag ctgccgaaag gtttttgata gctcctgcaa
     9121 aaagctgttc ggtaatattg agggcttgct ggtaggctac ctctccatga accagtgtca
     9181 ccacctcacg cgcaagcgtc ttttgagcga ggcgctcatg gcgtgctgcg ttgaactgct
     9241 cctcaatagc agcaatctca tcaagtgata agaaggtgaa gatcttcagg aagcgtaccg
     9301 catcatcgtc cataacattt aaccagaact ggtacatctc gtaaggagat gtttttttag
     9361 cgtcaagcca aatcgcatta ccctctgact tgccgaattt tttacctgtt gcatctgtaa
     9421 tcaatggcac tgtcatcaca tgtccagtct tgtcagcttt tttgcggagc aattcggtac
     9481 ctgctgtcat attaccccac tggtcagagc cgccgatttg cagtgtcaca ttgtgcttag
     9541 catttagctc gtaaaaatcg tagccttgca tgacctgata tgcaaattcg gtgtaggaaa
     9601 ttccggtttc gatacgtttt ttcactgaat ccttgctcat catgtaattg atagtgaagt
     9661 gcttgccgac atcacgaagg aagtcaataa agctaatctg tgagaaccag tcatagttgt
     9721 tgacaagctc agccttgttt tcaccgttgt caaagtcaag aaagcaagag agttgttctt
     9781 taatcttttg gctccaatca agaacggttt ccttggtttg taggctacgc tcagcgtctt
     9841 taaaggacgg atcaccaatc agcccagttg ccccaccgac aagagcgtag ggcttgtgtc
     9901 ctgctagctg caagcgacgt gatgtcaaaa tggcaacgag atgaccaaga tgcaggctat
     9961 cagctgttgg atcatagcca gtgtaatagg atacttgccc ttctgttaat gctttgacaa
    10021 gggcttcttc atcggtcgtt tgaaagacca agccacgagc tttgagttct tcaaaaatat
    10081 tcataggctt tctccatttt ctttatgatt tccgaatcat tatatcaaaa atgactgtgg
    10141 ctgtgcaagc ttaatcaaag tttggtataa tgaagattga ggtacgttat ggtgaaatgg
    10201 aaaaagaatc aaataagcaa aaatcatcag cgattagaat tagttgattt tggaacggtc
    10261 tttttgcgca cattaaaatt catgtcgagc tttttttatg tggctgtctt tttgtttggc
    10321 atgctgggtg ctggtatggc ctttggctat ttagccagtc aaattgactc ggtaaaaatt
    10381 ccaagcaagg aaagccttgt caagcaggtt gaatcattga ccatgatgtc acagatcact
    10441 tattcagaca atagcttgat ttcaggcatt gatacggatc tgcttaggac accggttgct
    10501 agtgatgcga tttcagataa tattaaaaag gccattgtct caactgagga cgacaacttt
    10561 cagcgtcata agggcgttgt accaaaggcg gtttttcgtg cgactctggc ctctgttttg
    10621 ggctttgggg agtcaagtgg tggctctacg ctgacacagc agttgattaa gcagcaagtc
    10681 ttgggcgatg atccgacctt taggcgaaaa tcaaaggaaa ttatctatgc actggcctta
    10741 gagcgttaca tgtcaaagga cgatatttta tcacattatt taaacgtgtc gccttttggt
    10801 cgtaataata agggacaaaa cattgcaggt gtggaggagg ctgcgcgtgg catttttgga
    10861 gtctctgcaa aggatttgac ggttccgcag gcggcctttt tggcaggact tccgcaaagc
    10921 ccgattgttt attcgccgta tttgccaaca gggcagttaa aatcagccga tgatatggcc
    10981 tatgggatta agcgccagca aaatgtcctc tacaatatgt atcgaacagg tgtgctgaca
    11041 gaaaaagaat atcgtgatta taaggcatat cctattagca atgattttat taaatctgaa
    11101 acagtcactg ccaatactca tgattacctc tactactctg tcttggcaga ggcacaaaag
    11161 gccatgtata gctatctgat caagcgagat aaggtgcctg ctaaagattt aaaaaatgat
    11221 gagactaagg ctgcctatga ggagcgggcc ttaactgagc tgcagcatgg cggctacact
    11281 gtcaaaacaa caatcaataa accaatccat caggtgatgc aaaaagcggc agctcagttt
    11341 ggtggtttgt tagatgatgg cactgggaca gtgcagatgg gcaatgtcct aacagacaat
    11401 gctacaggag ctgttttggg ctttattggt ggcagagact atgctcacaa tcaaaacaac
    11461 catgccttta ataccgttcg ctctccaggc tctagcatta agccgattat tgcttatgga
    11521 cctgccattg atcagggatt aatgggaagt gctagtgtcc tatccaacta tccgacgacc
    11581 tattccagcg gtcaaaaaat catgcacgtc gatagtgaag gaacagcaat gatgcccttg
    11641 caggaggcgc ttaatacctc atggaatatt ccagcctttt ggactcaaaa gctgctgcgt
    11701 gataagggcg ttgatgttga aaactatatg agtaaaatgg ggtatcggat tgctgattat
    11761 tccattgaaa gtctgccact tggtggtggg attgagacct cggtagccca gcagaccaat
    11821 gcttatcaga tgattgctaa taatggtctt taccaaaagc aatatatggt ggctagtatc
    11881 acagcaagtg atggatcagt tgtttatcag catgaggcta agccagttcg tattttttca
    11941 gctccaacag ccacaatttt gcaggagctc ttgagaggac cgatttcatc tggggcaaca
    12001 accaccttta aaagccggtt agcagggatc aacccaagcc ttgcaggtgc tgactggata
    12061 ggtaaaacag gaacaaccga aaattatacc gatgtctggc tggtcttagc tactccaagg
    12121 gttactttgg gtggttgggc aggccatgat gacaatacct cgcttgcacc actgacggga
    12181 tacaataata attcaaatta catggcttat ttggttaatg ccatcagtca ggctgatcca
    12241 aatatttttg gccttggtca gcggttttca ctggatcctg gcgttatcaa ggcttctgtc
    12301 ttgaaggcca ctggtctaaa gccgggtaca gtgacgatca atggccaaac catctccatc
    12361 ggtggagagc taacaaccag cctttgggct caaaagggac ccggagcaac tacctatagg
    12421 tttgccattg gtggaacaga cgcagactat cagaaagctt ggggaggttt tagtggtaga
    12481 agaaattagt tgtattttcc agaaaaatag tgtataatgt ctataactat ttgtcgtcta
    12541 atctagctga aatattgtcc agctagaaag aacagcagtt aaatcacact gataaggtca
    12601 gatttagctg ctctttttgt gcctattttt agataaaaat caattttgta acaaaaattt
    12661 aaagattcta aaaaatacca cttgagacaa atattgatgt tgcaattgtt tgcttgatag
    12721 caaagcttaa aaagaaaaag gagctaaaaa cttggcagga catgacgttc aatacgggaa
    12781 acatcgtacc cgtcgtagtt tttcaagaat caaagaggtt cttgatttac caaatttgat
    12841 tgaaattcaa actgattcat tccaagattt cttagattca ggcttgaagg aagtatttga
    12901 agatgtgctt ccaatctcaa actttacaga cacgatggag cttgagtttg ttggttacga
    12961 atttaaggag cctaaatata ctcttgaaga ggctcgtatc catgatgcaa gctattctgc
    13021 accaatcttt gtgaccttcc gcctgattaa taaggaaact ggcgaaatca aaacacaaga
    13081 ggtctttttt ggtgattttc cgattatgac tgaaatggga acctttatca tcaacggtgg
    13141 agagcgtatt attgtttctc agttggttcg gtctcctggt gtttatttca atgacaaggt
    13201 tgataaaaat ggtaaggttg gttatggctc aacagttatc cctaatcgtg gtgcttggct
    13261 agagctagaa actgactcaa aggatattgc ttatactcgt attgaccgta cgcgtaaaat
    13321 cccatttaca acgctagtgc gtgcacttgg tttttctggt gatgacgaaa tcattgatat
    13381 ttttggtgat agtgagcttg ttcgcaatac cattgaaaag gatattcata aaaaccaaag
    13441 tgattcacgt acagatgagg cccttaagga aatttatgaa cgcttaagac caggtgagcc
    13501 aaagacagct gatagctcac gcagcctttt gacagctcgt ttctttgatg ctcgccgtta
    13561 tgacttggca gcagttggtc gttataagat taataaaaag ctgaacatca agacacgtct
    13621 tttaaatcaa attattgctg aaaatctaat agatagtgag actggagaga ttctggttga
    13681 ggctggaaca gagatgactc gtagtgtgat tgagtcaatc gaagagcagc ttgacgggga
    13741 tttgaacaag tttgtctaca cacccaacga ttatgcggtg gtgacagagc ctgtaatcct
    13801 ccaaaaattc aaggtggttt caccagttga tcctgatcgt gtggtgacga tcgttggtaa
    13861 tgctaaccca gatgataagg ttcgtgccct tactccggct gatattttgg ctgagatgtc
    13921 ttatttcctt aaccttgctg aaggtcttgg aaaggtcgat gacattgacc acttaggtaa
    13981 tcgtcgtatc cgtgcagttg gtgaattgct tgctaaccaa ttccgtattg gtcttgctcg
    14041 tatggagcgc aatgtccgcg agcgtatgtc tgtacaggat aacgatgtgt tgactccaca
    14101 acagattatt aacattcgtc ctgtaacggc ggctgtcaaa gaattctttg gttcttcaca
    14161 gctatcacag ttcatggatc agcacaaccc attgtctgag ttgtcgcaca aacgtcgttt
    14221 gtctgcctta ggacctggtg gtttgacacg tgatcgtgct ggctatgagg tgcgtgacgt
    14281 gcactacact cactatggtc gtatgtgtcc gattgaaaca cctgaagggc caaatatcgg
    14341 tttgattaat aacctgtctt catttggaca ccttaacaaa tatggcttta ttcaaacccc
    14401 ttaccgtaag gttgatcgtg tgattggccg agtgactaat gagattgttt ggctaactgc
    14461 tgatgaagaa gatgaattta cagtagcgca ggctaattct aagctcaatc cagacggtac
    14521 ctttgctgaa gagattgtca tgggacgtca ccaaggtaat aaccaagagt ttcctgctag
    14581 ccaggttgac tttgttgacg tgtctcctaa gcaggtagtt gctgttgcga cagcatgtat
    14641 tcctttcctt gaaaacgatg actccaaccg cgccctaatg ggagctaaca tgcagcgtca
    14701 ggctgtgcca ttgattgatc caaaggctcc ttatgttggt acgggtatgg aatatcaagc
    14761 agcccatgat tcaggtgctg cggtaattgc ccagcataat ggtaaggttg tcttttcaga
    14821 tgctgaaaga gtagaggtgc gtcgtgagga cggttcactt gatgtttacc acatcacaaa
    14881 attccgccgt tcaaactctg gtactgccta caaccaacga acccttgtta aaataggtga
    14941 tattgttgaa aagggtgact ttatcgctga tggcccttct atggaaaaag gtgagatggc
    15001 tcttggtcaa aatccaatcg ttgcttacat gacctgggaa gggtacaact ttgaggacgc
    15061 ggttatcatg agtgagcgtc ttgtgaagga ggacgtttat acctctgttc acttggagga
    15121 gtttgaatca gaaacacgcg acacaaagct tggatctgag gaaatcacac gtgaagtgcc
    15181 aaacgttggt gaagaagccc tcaaggacct tgatgaaatg ggtattatcc gtatcggtgc
    15241 agaggtcaag gaaggcgata ttcttgttgg taaggtaact cctaagggtg aaaaagacct
    15301 ttctgctgaa gaacgtctcc tgcatgctat ctttggtgat aaatcacgtg aggttcgtga
    15361 tacctcgtta cgtgttcctc atggtggtga cgggattgta cgtgatgtga agatctttac
    15421 acgcgcaaat ggtgatgagc ttcagtcagg tgttaatatg ctggtgcgtg tttacattgc
    15481 tcaaaagcgt aaaatcaagg tcggagataa aatggccggg cgtcatggta acaagggtgt
    15541 cgtctcacgt attgtaccag ttgaggatat gccatatctg ccagacggaa cccctgttga
    15601 catcatgctg aaccctcttg gggtgccgtc tcgtatgaac attggacagg ttatggagct
    15661 tcacctaggt atggctgctc gtaatttggg tatccatatc gcaacaccgg tctttgacgg
    15721 agctacgtct gaggaccttt gggaaactgt tcgtgaagca ggtatggata gcgatgctaa
    15781 gactgttctt tatgatggcc gtactggtga gccgtttgat aatcgtgtgt cagttggtgt
    15841 catgtatatg attaagcttc accacatggt tgatgataag cttcacgcgc gttctgtagg
    15901 accatactca ctggttaccc aacagccgct tggaggtaaa gctcagtttg gtggccaacg
    15961 ttttggtgag atggaggtat gggctcttga ggcttatggt gcttcaaatg ttcttcagga
    16021 aatcttgacc tataagtcag acgatgtgaa tggtcgcttg aaagcttatg aggcgattac
    16081 caaaggtaag ccaattccaa agcctggtgt accagaatcc ttccgcgttc ttgtgaaaga
    16141 attgcaatca cttggtcttg acatgcgtgt ccttgatgaa gatgataatg aagttgagct
    16201 tcgtgatctt gatgaaggtg aggacgatga cgttatgcac gttgatgatc ttgaaaaagc
    16261 gcgtgaaaag caggctcagg aaactcaaga aattgctgaa tcaactgaag acaactaaat
    16321 cataaacatt tgtaacagaa ataatgacta gactagggct atttgcccta gctgctagta
    16381 agtcatcaaa ggcagaaagg taaaactagt ggttgacgta aatcgtttta aaagtatgca
    16441 aatcacatta gcttcaccaa gtaaggtccg ttcatggtcc tatggtgaag ttaaaaaacc
    16501 tgaaacaatc aactaccgta cattaaaacc agaacgtgag ggtctttttg acgaagtcat
    16561 ttttggacca accaaggatt gggagtgtgc gtgtggcaaa tataaacgta ttcgctataa
    16621 aggtattgtc tgtgaccgtt gtggggttga ggtaactcgt gcaaaggttc gtcgtgaacg
    16681 catgggacac attgagctaa aggcacctgt gtcacatatc tggtatttta agggtatccc
    16741 atctcgcatg ggcttgactc ttgacatgag tccgcgtgcc cttgaggagg taatctactt
    16801 tgccgcttat gtggttattg atccaaagga tacaccactt gagcccaaat cactattgac
    16861 agagcgtgaa tatcgtgaaa aaatccaaga atatggacat ggctcattca tcgctaagat
    16921 gggggcagag gccattcaag acctcctaaa gcgtgtcgat ttggcaacag aaattgctga
    16981 gctaaaggaa gaattaaaaa ctgcaacagg tcaaaagcgt atcaaggctg ttcgtcggtt
    17041 agatgtgctt gatgccttta ataaatcagg caataagcca gaatggatga tcctgaatat
    17101 cttgccggtc attccaccag atcttcgtcc tatggtgcaa ttggacggtg gtcgctttgc
    17161 agcctcagac ttgaatgacc tttaccgtcg tgtcattaat cgtaataacc gtttagcacg
    17221 tttgctggag cttaatgcgc ctggtatcat tgtgcaaaat gaaaagcgta tgctgcaaga
    17281 ggcggttgat gctttgattg ataatggtcg tcgtggtcgt cctattacag gacctggtag
    17341 tcgtccgctg aagtccttga gccacatgct taaaggaaaa caagggcgtt ttcgtcaaaa
    17401 cctgcttggt aagcgtgttg acttctcagg tcgttcagtt attgctgtag gtccaacgct
    17461 taaaatgtat caatgtggtg tgccacgtga gatggctatt gagcttttca agccatttgt
    17521 gatgcgtgag attgttgcac gcgaatttgc cggcaatgtc aaagcagcta agcgtatggt
    17581 tgagcgtggc gacgagcgca tttgggatat tctagaagag gtcatcaagg agcacccagt
    17641 gcttcttaac cgcgcaccta ctcttcacag gcttggtatt caggcctttg agccagtgct
    17701 tattgatggt aaggctcttc gtcttcaccc acttgtgtgt gaggcctaca atgccgactt
    17761 tgacggagac caaatggcca ttcacgtgcc gctttcagag gaagcacagg cagaggctcg
    17821 tttgttgatg cttgctgctg agcatattct taaccctaag gacggtaagc cagttgtaac
    17881 accttctcag gatatggtgc taggaaacta ctacctaaca atggaagatg ctggtcgtga
    17941 aggcgaaggt atggtcttta aggacaagga cgaagcggta atggcttacc gtaatggcta
    18001 tgttcacctt catagtcgtg ttggtatcgc tgttgacagc atgccaagca agccttggaa
    18061 ggatagtcaa agacacaaaa tcatggtgac aacagtcggt aagattttgt ttaatgacat
    18121 catgccagag gaccttcctt acctccaaga gccaaataat gctaacctga cagagggcac
    18181 tccagataaa tacttcttgg agccaggtca gaatattcag gaggttattg atagcttacc
    18241 gctcaatgtg ccattcaaga agaaaaatct tggtaacatc attgcggaaa ccttcaagcg
    18301 tttccgtaca acagaaacat cggcctttct tgaccgcttg aaggaccttg gctactatca
    18361 ttcaaccctt gcgggcttga cggttgggat cgctgatatt ccggttattg acaacaaggc
    18421 tgagatcatc gaggctgctc accatcgtgt tgaggaaatt aataaggcct tccgtcgagg
    18481 cttgatgact gatgatgatc gctatgttgc agtcacaaca acatggcgcg aggcaaaaga
    18541 agcccttgag aagcgtctga ttgaaacaca ggatcctaag aacccaatcg ttatgatgat
    18601 ggactcagga gcgcgtggta acatctctaa cttctcgcag cttgccggta tgcgtggctt
    18661 gatggctgct cctaatggcc gtattatgga gcttcctatc ctgtctaact tccgcgaagg
    18721 cttgtctgtt ttggaaatgt tcttctcaac tcatggtgct cgtaagggta tgactgatac
    18781 ggctcttaag acagctgact caggctatct gacacgtcgt ttagttgatg ttgcgcaaga
    18841 tgtcatcatt cgtgaggacg attgtggtac agaccgaggc cttcttattc gagctatcac
    18901 agatggcaag gaagtcactg aaacacttga ggagcgcttg cagggtcgat acactcgtaa
    18961 atcagtcaag caccctgaga ctggtgaagt attgattggt gctgaccaat taatcactga
    19021 ggacatggct cgcaagattg ttgatgctgg tgttgaagag gttaccattc gctcagtatt
    19081 tacctgtgct actcgtcatg gagtgtgtcg tcactgttac ggtatcaacc tagcgacagg
    19141 tgatgcggtt gaggttggtg aggctgttgg tactatcgct gcccaatcta tcggtgagcc
    19201 tggtactcag ctgaccatgc gtaccttcca cacaggaggg gttgcctcta atactgatat
    19261 cacacagggt cttcctcgta tccaagaaat ctttgaagcg cgcaacccta aaggggaagc
    19321 agttatcaca gaggttaagg gtactgtcat tgagattgaa gaggacgcat caacccgtac
    19381 gaagaaggtt tacgttcaag gtaaaacagg tctgggcgaa tatgtcgtgc catttacagc
    19441 gcgtatgaag gttgaggttg gtgatgaggt caatcgtgga gctgccctta cagaaggctc
    19501 cattcagcct aagcacctcc ttgaggtgcg tgataccttg tcagttgaga cctacttgct
    19561 tgctgaggtt caaaaggttt accgcagcca aggggtagaa atcggagaca agcacgttga
    19621 ggtgatggtt cgtcaaatgc ttcgcaaggt acgtgtcatg gatccaggtg atacagatct
    19681 tctgccagga accttgatgg acattgcaga cttcacagat gccaacaagg agattgttat
    19741 ctccggtggt attcctgcga cttctcgtcc agtgcttatg ggaatcacaa aagcctcact
    19801 tgagactaat tcattcttgt cggcagcttc cttccaggaa actactcgtg tgctgacaga
    19861 cgctgctatc cgaggcaaaa aagaccatct attggggctt aaggaaaatg ttatcattgg
    19921 taagatcatt ccagcaggta ctggtatggt tcgttaccgt aacattgaac cgcaagctat
    19981 caatgaggtc gaggttatcg aaggagctga agctacagaa gagccagcaa ttattgagga
    20041 ataagagata aaaggagcta gtcttagctc cttttatcat gctaaaatca ttagattaat
    20101 tgggctccat gtcaactata gtaggtgact gataactaag cacgagagga gacgaatttc
    20161 gtcttctctt gtaccatgtt caaagcaagg ggaatgcgtc tcttgaagtt gtcaaaggtt
    20221 ctgaatccaa aagattgcgc ttgatgtctt tgatcagttt gctagtcgct tcaaacttgg
    20281 cgttagaata aggtagttca atagcattag tgatatagtc t
//
LOCUS       DARYSY010000039        19762 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYSY010000039 DARYSY010000000
VERSION     DARYSY010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19762
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            19..468
                     /locus_tag="TVR04_001354"
     CDS             19..468
                     /locus_tag="TVR04_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270038.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEEPAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            899..1591
                     /gene="pyrF"
                     /locus_tag="TVR04_001355"
     CDS             899..1591
                     /gene="pyrF"
                     /locus_tag="TVR04_001355"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1270039.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYIKSLGHSVFLDLKLHDIPNTVRSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLIASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKAEVPVGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITRAADPV
                     KVYHQIKAEWNR"
     gene            1651..2286
                     /locus_tag="TVR04_001356"
     CDS             1651..2286
                     /locus_tag="TVR04_001356"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1270040.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKDPFTWASGITSPIYTDNRITLS
                     YPKTRTLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMNLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            2338..3081
                     /locus_tag="TVR04_001357"
     CDS             2338..3081
                     /locus_tag="TVR04_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1270041.1"
                     /translation="MTYKDLLEMGETIYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            3313..4767
                     /locus_tag="TVR04_001358"
     CDS             3313..4767
                     /locus_tag="TVR04_001358"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1270042.1"
                     /translation="MTFKDATEMAQAVREGRVSPLALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYLVQ
                     RLEELGFIILGRSNTPEFGFKNISDSHLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQLQP
                     SKELIDKLAKTECYPSSQRLELVEVMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGVARQFEQAGLLKLPS"
     gene            4887..5753
                     /locus_tag="TVR04_001359"
     CDS             4887..5753
                     /locus_tag="TVR04_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1270043.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            5781..6434
                     /locus_tag="TVR04_001360"
     CDS             5781..6434
                     /locus_tag="TVR04_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1270044.1"
                     /translation="MIDLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRGYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            6565..6972
                     /locus_tag="TVR04_001361"
                     /pseudo
     CDS             6565..6972
                     /locus_tag="TVR04_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            6984..7637
                     /locus_tag="TVR04_001362"
     CDS             6984..7637
                     /locus_tag="TVR04_001362"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1270045.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETKVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKYRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLK"
     gene            7870..9144
                     /locus_tag="TVR04_001363"
     CDS             7870..9144
                     /locus_tag="TVR04_001363"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1270046.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEAEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPGHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(9198..9845)
                     /gene="plsY"
                     /locus_tag="TVR04_001364"
     CDS             complement(9198..9845)
                     /gene="plsY"
                     /locus_tag="TVR04_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1270047.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNVSPIAIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPGYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            9978..11927
                     /gene="parE"
                     /locus_tag="TVR04_001365"
     CDS             9978..11927
                     /gene="parE"
                     /locus_tag="TVR04_001365"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1270048.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIASAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PIVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            12026..12842
                     /locus_tag="TVR04_001366"
                     /pseudo
     CDS             12026..12842
                     /locus_tag="TVR04_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
     gene            13316..15775
                     /gene="parC"
                     /locus_tag="TVR04_001367"
     CDS             13316..15775
                     /gene="parC"
                     /locus_tag="TVR04_001367"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1270049.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDYTEKEPTVLPAAFP
                     NLLVNGSSGISAAYATDIPPHNLSEVIDAVIYMIDHPKAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKGRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPGIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGNEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAITNFAADEMVIYAELIQSFEQGLYASVTQHGLIKRFERKEMMPW
                     RSYKSKSIKYAKLKAADDRIIAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLLVLRELKTK
                     PHRVFLAGMVKGDTTIGTIDLFTHDSEDTANDQQLEIISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            15876..16898
                     /locus_tag="TVR04_001368"
     CDS             15876..16898
                     /locus_tag="TVR04_001368"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1270050.1"
                     /translation="MTTAIDWENLGFEYRKLPFRYISYYKDGKWDAGRLTEDATLHIS
                     ESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFIDA
                     VKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFTVFAMPVGNYFKGG
                     LAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTKI
                     EEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLDR
                     FVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPEG
                     WIVAID"
     gene            16966..17196
                     /locus_tag="TVR04_001369"
     CDS             16966..17196
                     /locus_tag="TVR04_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1270051.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            17257..17337
                     /locus_tag="TVR04_001370"
     tRNA            17257..17337
                     /locus_tag="TVR04_001370"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17291..17293,aa:Tyr,seq:gta)
     gene            17376..17447
                     /locus_tag="TVR04_001371"
     tRNA            17376..17447
                     /locus_tag="TVR04_001371"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17408..17410,aa:Gln,seq:ttg)
     gene            17575..18777
                     /gene="rpsA"
                     /locus_tag="TVR04_001372"
     CDS             17575..18777
                     /gene="rpsA"
                     /locus_tag="TVR04_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1270052.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRRQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
     gene            19093..19164
                     /locus_tag="TVR04_001373"
     tRNA            19093..19164
                     /locus_tag="TVR04_001373"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19126..19128,aa:Arg,seq:ccg)
     gene            complement(19222..>19762)
                     /locus_tag="TVR04_001374"
     CDS             complement(19222..>19762)
                     /locus_tag="TVR04_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1270053.1"
                     /translation="GKKADNLIQRQFEAAKPYEKCYTDVTEFALPNNDEKLYLAPVLD
                     GYNSEIIDFTLSRSPDLKQVQTMLEKAFPDQSYHGTILHSDQGWQYQHQSYHHFLESK
                     GIRPSMSRKGNSPDNGMMESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYNNKR
                     IKTKLKGLSPVQYRTKSFQ"
BASE COUNT         5681 a         3756 c         4772 g         5553 t
ORIGIN      
        1 ggtggtgatg gtgtaaatat gactggacaa agtagtcatc aggtattaat tcaaaagctg
       61 ttggtcagca ctcactattt gacattattt agagatgagc tgaagctagt tgagaggaca
      121 ccatctattt tgggaagtga attccctgtc tctcttgtcc aaacggaatt aggtgatatt
      181 atcaccttgg tggatacctt aaataagcag cagcgtttga ttgagtcgac cttttggtat
      241 gaggagccag ccttcaagct catgaacaag gccttagata ttgttgataa ttggataaaa
      301 gggatagatg gcttgattaa gctctgccag tccaaggagg tctttcaggc cattgttggt
      361 gataaaagaa cgcgtgtttt tggtgtttta attgatgttt tttcctctct aaaaattagc
      421 accatgtcat tgaaggaatt tgctgctccg gctgctcttt gccattagat taggctggac
      481 taagcttggg tagtgactgg ttaagtcttg taggacgcct ctctcatgac aagtctaggc
      541 tttagggtga gtagtgtgct aagggtgtat tacatgttgg ctgtttttag acttagcctt
      601 gttaggttag ctgtgagtga tgtcaaaacc ctttgacagg ggctgtaaaa aaagctataa
      661 tggttaagat aagttacctt taagtgagtc cagagaggcg agcaaggtac acaggataag
      721 gcgagagggc ttgctctctt gattttcgtg tagcctcgct tctttggaag tgaggctttt
      781 atgatgtgac tttcagttgg tcttgtagca aggatccata agaccagtaa accgctcgtt
      841 agacgggtgg gcatgattta tttgggagta ttcccaaact gcatagaaag gataggttat
      901 gcgagaagaa cgccctatta ttgccttaga ttttccttcc tttgaggagg tcaagtcatt
      961 tttgtcgctg tttccagctg atgagaggct atacgttaag attggtatgg aactgtatta
     1021 tgctgaagga ccagacattg tccgttatat caagtcctta ggccacagtg tttttctgga
     1081 tttgaagctg catgatattc caaatacagt cagatcaacg atggcagtcc tatcaaggct
     1141 tggtatagac atgacgactg tgcaggctgc tggaggtgta gagatgctta gagcagcgcg
     1201 tgagggcttg gggcagggtc cgatactcat tgcggtgacg cagctaacat caactagcga
     1261 agagcaaatg cgtgaggatc aaaatattca atccacactg atagcatctg tgcttcacta
     1321 tgccaagcgt accgctcagg ctaagctaga tggtgtggtt tgctcagccc atgaggtcaa
     1381 ggccattaag gcagaagtgc cagtaggctt tgtgtgtttg acacctggga ttcgcccaac
     1441 aggtgctgat atcggagatc aaaagcgagt gatgacccct catcaagcta gagctatcgg
     1501 aagtgactat attgttcttg gtcgtccaat cactcgggct gcagaccctg tcaaggttta
     1561 tcaccagatt aaggcagagt ggaaccgtta gcagcaggat catcatgaca catgtagctg
     1621 ggctatgaca ccaaggaaaa gaggagaaaa atgacattag cagcacaaat tgcaacagat
     1681 ttacttgaga ttaaggccgt ttacctaaga ccaaaggatc cctttacttg ggcatcaggc
     1741 attacatcac cgatttatac ggacaatcgg atcactcttt cttacccaaa aaccagaacc
     1801 ctaattgaaa atggttttgt ggagacgatt aaggcagtat ttccagaggt tgaggtgatt
     1861 gctggcacag caactgctgg tattccacat ggtgcgattg ttgcagataa gatgaacctg
     1921 ccttttgcct atatccgcag caagccaaag gatcatggag ccggcaacca aatagaggga
     1981 catgtgcgtt gtgggcaaaa aatggtgatt atcgaggact tgatttcaac aggtggatca
     2041 gttcttgaag cggcagcggc agctagtcgt gagggggctg atgtgttagg agtagtggcg
     2101 atttttacct atgaattgcc agtagcaagc atcaattttg aaaaggcagg gctttctttg
     2161 gtgaccttgt ctaattattc agacctcatt aaggtcgcta aggctaaggg ctatattgat
     2221 gctgatggct tagccttatt aaaaagattt aaagaggatc aaaagcattg gcagcatgag
     2281 agttaaacag tactgaaaag ctgctgacat gctgatcatg tcttaaggag agaaaaaatg
     2341 acttacaaag acttacttga gatgggtgag accatttatt atcagacgga tcgcttgact
     2401 tactacaaaa atcctgtggt atctgagcgc tattttgata attaccttag ctatcgtagc
     2461 atgccttctt tggctgattt gaaaaaggac ttggcctatg tggcaaaaga gcagcaggat
     2521 tatcctagtc actacgcctt tctctttttt gctgaaaatg aggagctaag tacagacatg
     2581 cgagcttatt tgacagatca tcactttagc cttgaaaagc acctgatctt taccaatgag
     2641 ctggcaaagc ttcacctaaa ggagcgtgat atatcaccag tcactattga acagctctca
     2701 gaaacaagct tttctgccta tctggcttac aaatatcagg ctaatttggc ttatggtgaa
     2761 acctatgcca atcaatgcaa ggctgataat gaagccaatc tattgacaaa cggctcaacc
     2821 atttatttag ccatcaagga agggaagatt atcggagata ttacggcttg ggaatgtggc
     2881 gactatattg aaatggacga tttcagtgta gatgaggcct atcgtggtcg tggtatcggt
     2941 acagccttac agcgtaaggc cagtcaaggc tataagaagg tcattctcat ctcagaagaa
     3001 gctaatcgcg ccatgtatga acaccaaggc tatcaggagg ttgcttacta ctggacagcg
     3061 ctaaaaacat cgactagata agtgataaag aaacagatta taggattgaa ggtgtgggct
     3121 cttatgagta tgactcttca atcctttttt tctgagcgca tttgctaatc atacctgatg
     3181 aataagtcgt agcctgtcta gtggctcgtt ttaatggcgt cttgttctgc tttatggtta
     3241 aatataagaa aaaagttatt gctagggcat gcttgttgat ctagcaaggc tgatggatag
     3301 gatagggaac tgatgacttt taaagatgca acagaaatgg cacaggctgt tcgagaaggc
     3361 agggtaagcc ccttagcctt agtgagagac acgatcaaaa aggctcaagc actcaatcct
     3421 gagttgaatg ctattacctc agagcgtttt tcagaagctc ttgctgaggc agcagcaagg
     3481 gatttttctg gaaagccatt tgctggtgtg cctatttttc taaaggattt agggcaggag
     3541 caggaggggc agttggccac tgcaggatcg gtgttattta aggattatcg tgcttcaaaa
     3601 actgattatc ttgtgcagcg actagaggag ctgggcttta ttattttagg aagaagcaat
     3661 acgcctgaat ttggctttaa aaatattagt gatagccact tacatggtcc ggtaaatctg
     3721 ccacaggata agagtcgtaa tgccggtggc tcatcaggtg gagcagcagc tcttgtgtcc
     3781 tcaggaatca ccttgctggc tcctgctagt gacggaggag gatccattcg gattcctgcc
     3841 tcctttaatg gcttgatcgg tttaaagcca agcagaggaa gagtgcctgt ggggccaggc
     3901 tcttatcgtg gctggcaggg ggcgtctgtt cattttgctc taacgaggtc tattcgagac
     3961 acaagtcgtc ttctttatca cttgcaggtt tatcaggtag aaagcccttt tccattagtg
     4021 ccattaacca aagaagagct ttttcaccct ttagacagac ccttaaggat tgctctttat
     4081 gatcacatga tagatggaac taccgcctct atagatgctc agacagcttt aaccgaggcc
     4141 tgtcattttc taaaagagat ggggcatgag gttgtgcgat tagataagct tcctctagat
     4201 ataccaaagg ttatgaggga ttactacctg atgactagtg ttgagacagc tgccatgttt
     4261 gctgatagcc aagaagccct tggtcgtcag gtgaccaaag cagatatgga ggtcatgacc
     4321 tgggctatct atcaagcggg taaggatatt cttgcttcgg tctattctca ggcgctgcag
     4381 cgctgggatc attatagtgc tgaaatggca agctttcatg agcagtatga tcttttgctg
     4441 acctttaccg ccaatacgcc tgctccaaag catggacagc ttcagccaag caaggagcta
     4501 atagataagc tggctaagac ggaatgctac ccctccagtc agcgcttaga gctagtagaa
     4561 gtcatgtttg agcagagctt gttcataacc ccttacacag ctttggcaaa tctgacaggc
     4621 caaccagctc ttagtttacc aacctatgaa acgtctgctg gattgccgat gggcattcaa
     4681 ttgatagctg ctaaagggcg agaagactta ttgctgggag tagctagaca gtttgaacag
     4741 gctggattgc taaagctacc tagttaaata ttataaaaca gagctaatct attataggtt
     4801 agcttttttg ttaaatcgag catatctagt ctcttataag attagtcaat gctatactgt
     4861 cattaataat gaaaaaggag ttcttgatga aaaaaggagt tgctttactt tctgttagct
     4921 tggcgagctt gctgttagcc gcctgtgggt cacagccatc agctcaaaaa acaagctggg
     4981 aaaagattaa agataaaggt gttttaaagg ttgctacgcc tgcgacctac cagccaacat
     5041 cgtactataa tgatgccaat gaattggtcg gctatgaggt tgacctgatg aaggaaattg
     5101 gaaaacgcct tgatcttaag gtgaagttca ttgaaacagg ctatgatcag gcttttactt
     5161 cggttgatag cggtcgtgtt gatgtttctc tcaataattt tgacattaca gccaagcggc
     5221 aaaaaaaata caacatctca acgccttata agtacggtgt tggaggaatg attgttcgtg
     5281 ctgatggtag ctcaggcata agcaaggctg acctaagcga ttggaaaggg aaaaaagcag
     5341 ctggcgcctc tggtacagaa tacatgaagg ttgccaagaa gcaaggtgct gaattagtca
     5401 cctatgataa tgtgacgggt gatgtttacc tgaacgatgt tgctaatggc agaacagact
     5461 ttattcccaa tgattatcct gcacaaaagc tttttgtgga ttacatgaag tctcaaaatc
     5521 ctaacctcaa tgtcaaaatg agtgatgtgt tgtataatcc gacagcacag ggcattatca
     5581 tgagtaaaaa agatgacacc cttaagaaaa agattgatgc ggtcatcaaa gatatgaaac
     5641 aagatggcag cttgaaaacc atttcaaaga catattatgc tggtcaggat ttgaccgttc
     5701 cttttggcaa ggacaagaaa attccagtca ttgatgccag tgatgtggac tagtgtctta
     5761 gataaaggag ctctaaagca atgattgatc ttagattgat actagagagc ttgggctttg
     5821 ttttatcagg cttgccctat accttaggca tttctttttt aagctttcta acaggtcttt
     5881 tgttgggctt gcttttagcc tttttaaggc gttctactag ccactttagc cattatctgg
     5941 ttagaggtta tgtgtccata atgcgtgggg ttcctatgat tgtggtactc tttgttcttt
     6001 attttgggct tccctattat ggcttagagc tgtctgcctt gctatgtgcc tatttgggct
     6061 tttcactggt tagtgcagcc tatatctctg aggtctttcg tgcctcgatt gatgctattg
     6121 atcaggggca gtgggaggca gcaagggctt tggggctgcc ttatgtcagc attgtcaagc
     6181 atgtgattct gcctcaggcc tttcgtattg ctattccgcc tttaggaaat gttgtgattg
     6241 atatggtcaa aagttcgtct ttggcagcta tgattaccgt tcctgatatt tttcaaaagg
     6301 ctaaaattat tggtggcagg gagtgggatt acatgtctat gtatatcttg gttgccttta
     6361 tttattgggt gattgccttt ttgctggagc gctgtcaggg ctttttagaa aagaggctgc
     6421 gcttactctc ttaaaaaccg aatatttacc ctagaaatat tgtatttcta gggtttttat
     6481 gataaaaata tgatagacta aagtagccta atcagttagc tagctttgtc aagaactgac
     6541 tggctagagt gttggaggta ggatatggca gactctattg tatttcggaa aaatcatatg
     6601 atttcaactc aggcatttgc tcgagtgctg gaagcctcag ggattaaaag accgactaag
     6661 gacgaggcta gataatcgca aatgctaaag cattccgatt atctatggac agcatgggaa
     6721 ggtgacaagt tggttggtgt tgctagagct cttactgact atgcttatgt ctgctatatt
     6781 tctgacctag cagttgacca ggcatatcag ggtcaaggga taggcaagca attgctgtct
     6841 tttatctcag aggatcttgg agatactgtt gctcttgtat tgctgtcagc accttcggcg
     6901 atgtcctatt accctaagct tggctttgaa caatcagaca aagccttcgt tattccacga
     6961 aaaccgtttt agagaggtat ttaatgacac attcagcttg gcatgatgag attaagcagg
     7021 tgttacctaa ggattattat cggcgtatca atcgcttttt agatgaggtc tatgcgactg
     7081 gagtggttta cccgcccaga gacaatgtgt ttaaggcctt acaggtaacg ccattagaag
     7141 agacaaaggt gcttatttta gggcaggatc cttatcatgg ccctcttcaa gctcagggac
     7201 tttccttttc agtgcctgac tccattcctg ctccgccatc tttgcaaaat attttggagg
     7261 aattagcagc agatattgga gtaaggaatc atcacgatct tagcagctgg gctgagcagg
     7321 gagtgttgct cttgaatgcc tgcttgaccg ttccagaagg acgcgccaat gggcatgcag
     7381 gtctcatctg ggagcccttt accgatgcgg ttataaaggt cttgaatgct aagtataggc
     7441 ctgttgtgtt tatcctctgg ggagcctatg cgagaagaaa gaaggccttg attactaatc
     7501 cgattcacca tgttatcgaa agccctcacc ctagccctct gtcagcctat cgtggctttt
     7561 ttggcagcaa gcccttttca agagctaacg ctattttaga aaaagaaggc ctaggacaga
     7621 ttgactggct aaagtaggta ttgagacagg ctattatggc taagcaggaa gattgctcac
     7681 taaagttatc catctttgga gctttgggca tgcctagcta aatagagatt gatgatatca
     7741 gggatcaaga cagtcatgtc agatatggca agtaaaacaa gcaatcgctg cccagttaaa
     7801 tcggaagtca ctaaggttat gcttgattat cctgataagc agataagtag atttgacata
     7861 ggaggggtca tgttattaat taaaaatggg cgtgtgatgg atccaaaatc acagctagat
     7921 caggtggcag atgtcttaat tgataatgga aggattttac ggattgctcc agacattgag
     7981 catgatgagg cagagcagat cgatgccagt ggactcgttg ttgctcctgg tttagtggat
     8041 attcatgttc attttagaga gcctggtcaa acgcacaagg aggacataca tacaggtgct
     8101 ctggcagcag cagctggtgg ggtgacaaca gtagtcatga tggcaaacac caatcctgtt
     8161 atatcagata cggaaacctt acaggctgtt ctagcaagtg ctgctaaaga aaaaattaac
     8221 atttatacca atgctagtgt gaccaagcgg ttcaatggcc aagagctaac agactttaaa
     8281 gcgctcttag cagctggtgc ggtcagtttt tctgatgatg gcattccttt agagagctcc
     8341 aaggtcttaa aggaagcatt ggatttggct aaggccaaca agaccttcat tgccctgcat
     8401 gaggaggatc cccaattaaa cggtgtcctt ggcttcaatg agcatatcgc taaggatcat
     8461 tttcattttt gtggcgctac tggtgtggca gaatatagta tgattgccag agatgtgatg
     8521 attgcctatg atcgacaagc tcatgttcat attcaacatt tgtctaaggc tgagtctgtt
     8581 aaggtagttg cctttgctca gcagctaggt gccaaggtta cagccgaggc gacgccgcag
     8641 catttttcta aaacagagga ccttttacga cttgcagggg caaatgccaa gatgaatccg
     8701 cctctaagaa cagaacaaga tagattagca gtcattgagg ggctcaaatc aggtgtcata
     8761 gctattattg caacggatca tgcaccacat catcgtgatg aaaaggctgt tgctgatctg
     8821 accaaggcac catctggaat gaccggctta gaaacctcat tgtcattagg cctgaccaat
     8881 cttgtggagc cgggccatct ttcattgatg gcattattag agaagatgac cattaatcca
     8941 gcctcactat atagctttga tgctggttat ttggccgaat ctgggccagc tgatcttgtt
     9001 atttttgctg acaaggagga gcgtttggta acagaagcct ttgcttcaaa ggctagtaat
     9061 tcacctttta ttggggaaac cctaaaggga gttgtgaaat acaccattgc taagggacaa
     9121 attgtttatc aggcagacaa ctaatcaaca cttaaaaagc tgagcatctg atagtaactt
     9181 atgctcagct ttttgattta gtgatggctt gcgggctgct gcttgcttaa gttcaagccc
     9241 caaggaatga gattttcaga ttgctgcttg attcgcttca tattatcctg atgccttagg
     9301 ataatgattg ctgctagcac aacgatggta atggttaata gccaatcgta gccaggcaat
     9361 aaaaagtggg cggcaggaaa agtcagaaca ctaatcacag ctactacaga cgctgttaga
     9421 ctagccagtg aaatcatgct aaacaaataa agcgttagca caaacacagc cgctaaaaaa
     9481 aggagataga gtggggcaaa gcctagcaag acaccagcac tggttgcgac tgcctttcct
     9541 cccttgaagc cagcgaaaat aggaaaggta tgccctagga cagcaaaaaa accaatagca
     9601 attggtgaga cattgctagc gccaaccaaa accggaagaa gcgtggcaag cgtgccctta
     9661 aaaatatcaa ttaataaggt tgcagcacca gcctttagcc caagaatccg aaaggtattg
     9721 gtcgtaccgg tattacctga gccatgctca cgcaggttga tgttatagaa atattggcca
     9781 atccataggc ctgttggaat ggagccaagt aaatatgctg taagaattaa taggatcaat
     9841 ttcataacat acattatatc ataatgattg atttaagcgg aagcagttac aaagaattac
     9901 gaaaaaatct taaattattt tgcaaaattc tcaaaaaacc tgtaagataa aaaagatgaa
     9961 aacgtctgga ggtcaacttg gctaagaaag aaataagcat aacaaattat aatgatgatg
    10021 ccattcaggt cctagagggc ttagaggcag ttcgtaaaag accggggatg tatatcggat
    10081 caaccgatgc aaccggactt caccatttga tttgggaaat tgtcgacaat gctgttgacg
    10141 aggccttatc tggctttgga aatgagatcg atgtgacgct aaacaaggac ggttctgcca
    10201 ccatctctga cagcggacga ggcatgccga ccggacagca cgcccttggt ataccaactg
    10261 ttcaggtcat ctttaccatc ttgcatgcag gtggtaaatt tggtcaaggg ggctataaaa
    10321 cctcaggagg cctgcatggt gtgggctctt cagttgtaaa tgccctatcg tcatggctag
    10381 aggtggaaat cacgagagac ggagcggttt acaagcagcg ctttgaaaat ggcggtaggc
    10441 cagtgacagg cttggaaaaa atagcttcag ctccaaaaag caaatcaggg acaagggtta
    10501 ccttcatgcc tgatgacaag attttttcga caactgagtt caagtggaat accatcgcag
    10561 agcgtctgaa ggaatccgcc tttctgctaa agacggttaa aatgaccttg actgatctac
    10621 gaggtgacga tccgatcgtt gaagagtttc attatgaaaa tggtgttcag gattttgttg
    10681 cctacctcaa tgaggacaag gaaaccttga cccctgtgat ttacatggaa ggacaggagc
    10741 aggattttca ggttgaggtc gctttgcaat acaatgatgg gttttcagat aacattttgt
    10801 cctttgttaa caatgttagg acaaaggacg gtggcagcca tgaaactggc ttaaaatcag
    10861 ctattacaaa ggccatgaat gactatgccc gcaaaaccag cctactaaag gaaaaggata
    10921 aaaacttgga gggctcagat tatcgtgagg gcttgtctgc agtgttatcg atccttgtac
    10981 cagagcagca tttgcaattt gaagggcaaa caaaggacaa gctaggaagc ccactggcaa
    11041 ggccgatcgt tgagagcatt gtatcagaaa agctgacctt ctttttactt gaaaatggtg
    11101 agctagcagg tcatttgatt cgtaaggcta tcaaggcaag agacgcgcgt gaggcagcca
    11161 gaagagcgcg tgatgagtct cgaaatggta agaaaaacaa aaaggacaag gggcttcttt
    11221 ctgggaaatt aaccccagcc cagtccaaaa atcctaagaa aaacgagctg tacctagtcg
    11281 agggagattc agccggtggc tcagctaagc agggtaggga tcgtaaattc caggcgattc
    11341 tccccttacg tggtaaggtt ttaaacacag aaaaggccaa gatggctgat attctcaaaa
    11401 atgaggaaat caatacaatg gtttatacta ttggtgcagg tgttggtgct gatttcaatc
    11461 ttgatgatat taattacgac aagattatta tcatgaccga tgctgatacg gacggggccc
    11521 atattcagac cctgctgttg acttttttct accgttatat gcggccgctt gttgaggcag
    11581 gacatgtcta tattgccttg cctcctcttt ataaaatgtc aaagggtaaa ggcaaatcgg
    11641 agaaggtttc ctatgcttgg acagatggtg agctggagga tcttcgcaag gaatttggta
    11701 aaggtgcaag tctccaacgc tataagggac ttggggagat gaatgccgat cagctatggg
    11761 aaaccacgat ggaccctgac acacgaaccc ttatccgagt gacgattgat gacctggcta
    11821 gggcagagcg acgcgtttca gtcctcatgg gagataaggc tgccccacgc cgtcaatgga
    11881 ttgaggacaa tgtcaccttt accttggagg aaaatacggt tttttaaggc atttttccta
    11941 aggaaggtcc taacatatct tatatcaaat tgctattcgt gtgctcagta ttcatttatc
    12001 aaggataacc atcgaggtaa cagtgatgaa gctagacatt tgccaacaaa gctacagtct
    12061 tcagtggggg aggcacctat tattttgcgt taacagatta tcccaatatc aaggcttggg
    12121 aattggaaaa gatagcagcc ttttatgcct acgaagcctt acatcatcgc caaacagaca
    12181 ttagctgtca ggacagcaag cttcttgaaa aggttcatca atttcttgaa gcacatgctt
    12241 gtgcctaacc ctgtaggcct agctgtaaat tggtggcttc aacatttaac atcaatggag
    12301 aggcagtctg ttgtccttat ttaagtcata cctgcactgt agcggctgct ctaagtattt
    12361 tcaagacagg aaagctcctg tctgctgtaa gagcttttgg ggtaacggcg caggagttag
    12421 ctgagagtga gcgaaatgct gctggtgatc ctgctgatta ttttcattat gtgatgcttg
    12481 gctggtccaa tacgacctcg ggctatcgct tggctatgga gagattgctc aatcgtatgc
    12541 caaatgaaaa ggacttaagg gagcattttg tgcccggagt gagctttcac tatagctatt
    12601 ctgatatttg tcagatgaaa ggttatgttt ttgatggtta tcaccctgcc aaggtaaaag
    12661 acgagcttag cttggagaaa ttgcaggctt gtattgctcc taaaagctgg cagcagcgct
    12721 ttgaagcggt tattccaaag gccttgcgct caaaggttca ttacctagac tatagaggtg
    12781 aaggcttagt tgagtggtct aatagggttt atcagctgtt acgagcgatc agtgacagct
    12841 agctgtaaat aggctagctt tatgctattt tttgaatatc atagacaatc taacaaaaag
    12901 gaaagtccag tgagaagtct tttgatgggt gcgggatggc tttcctgaaa aatgctaatc
    12961 ctagagatag gcgagcgtag cgagcccatt ctgaaagctt ctgccgtagt gaaaagaaga
    13021 taatcgctta cgattatctt cgagggaaat ttcgagactt cagctcgaaa tttaggaatg
    13081 gaatcgtagg ttcgcttctg tccccactac ctaaaggagc tttcaaaaaa actaattaaa
    13141 gaaagagata tctttctgaa agaaacaaag aaaggaatgt tcagctagtt tactaactga
    13201 atacgggact atttttccta gaaaaatcgg taacctccta atgtccaagg acacgtcgtc
    13261 aattccagca ttttttacgg aaaaatttcg caagcgaaac gtccctttgt atcttatgag
    13321 taatattcaa aacatgtccc ttgaggacat catgggagag cgttttggac gctactccaa
    13381 atacatcatt caggagcgag cgcttcctga tattcgagat ggtctaaagc ctgttcagcg
    13441 ccgcattctt tattctatga ataaggacgg taataccttt gaaaagggct accgcaagtc
    13501 agccaagtct gttggtaata tcatgggcaa tttccacccg catggagatt cttcgatcta
    13561 tgacgctatg gtgcgcatga gtcaggattg gaagaatcgt gaaattcttg ttgaaatgca
    13621 tggcaataat ggctctatgg acggcgatcc accagcagct atgcggtaca ctgaggcgag
    13681 attatctgaa attgctggtt atctgttaca ggacattgat aaaaaaacag tgccatttgc
    13741 ttggaatttt gattatactg aaaaagagcc aacagtattg ccggctgcat ttccaaatct
    13801 attggtcaat ggctcatcag ggatctcagc agcctatgcc acagatattc caccacataa
    13861 tttgtcagag gtgatcgatg ctgttattta catgattgat cacccaaagg ctaagctaga
    13921 taagctaatg gagctgttac cgggacctga ttttccaaca ggtggtatta tccaaggagc
    13981 agccgaaatt aaaaaagcct acgaaacagg taagggccgc gttgttgttc gctccagaac
    14041 tgaaattgag gatctaaagg gaggcaagca gcagatcatt gtgaccgagc ttccttatga
    14101 ggtcaataaa gctgtcctag ttaaaaaaat tgatgatgtt cgggttaata acaaggttcc
    14161 aggcatagca gaggtgcgtg atgagtcaga ccgtacaggg ctacgcattg ctattgagct
    14221 caaaaaagac gctgacagcc aaaccatctt gaattatttg ttgaagtata ccgagcttca
    14281 agtcaattat aattttaata tggttgcgat tgatcatttt acgcctcgtc aggttggatt
    14341 gcaaaaaatc ttatcaagct atatcgctca ccgcaaaagt attattatca agcgctctca
    14401 gttcgacaag gaaaaggctg aaaagagatt gcatattgtt gagggcttga tacgtgtctt
    14461 atctatttta gatgagatta tcgcgctgat ccgagcttct gacaataagg ctgacgccaa
    14521 agaaaaccta aaggtcagct atgacttttc agaggaacaa gcagaggcta ttgtcacctt
    14581 acagctttat cgactgacca atacagatat tgttaccctt cagcaggaag agcatgacct
    14641 aagagagctc atcacaactc tctcggctat tattggtaac gaagcaacca tgtataacgt
    14701 gatgaagcgt gagctaagag aggtcaagaa aaagtttgca gggccacgtt tatcagagtt
    14761 gcaggctgaa agccaagcga ttgaaattga ttctgctagt cttattttgg aggaagaaac
    14821 ctttgtcagt gtgactcagg gaggctatat caagcgaaca agccctaggt catttcatgc
    14881 ctcaagcctt gaggaaattg gtaagcgcga tgatgatcat ctgatctttg ttaagcaggc
    14941 taagacaaca gaccacctgt tactctttac caatctaggt aatgttattt atcgcccagt
    15001 ctatgagctg actgacttgc gctggaaaga catcggggag catttatcac aggctattac
    15061 taattttgct gcagatgaaa tggtgatata tgctgagttg atccagtcct ttgaacaagg
    15121 actctatgct tcagtgacac agcatggact gattaaacga tttgagcgca aggagatgat
    15181 gccttggcga agctacaaat caaaatcaat caaatacgct aagctaaagg ctgctgacga
    15241 ccgtattatt gcgatagcac caattatcat ggaagatctt cttttggtga cgcagcaggg
    15301 ctacgccttg cggttttcta gccaagaaat accgattcag ggcctaaagg ctgccggagt
    15361 taaaggaatt aacctaaagg ctcaggatta cttggtttct gcctgcccag tcaatgctga
    15421 ttccttcttt gtgctgacgc aaagaggagc actaaagcga gtggcgattg ctgatattcc
    15481 acagaccagc cgagctaaca gaggtctgct ggtgttacga gaattaaaga ccaagccaca
    15541 cagagttttc ttggcaggaa tggtaaaagg agatactaca ataggtacca ttgacctatt
    15601 tacacatgat tcagaggaca cagctaatga ccagcaatta gagattatta gtaagaccgg
    15661 tcagcaatac cagcttgctc tcaatagcct gtctctatca gataggacaa gtaatggctc
    15721 ctttatttca gagagcattt cagatcagga ggtcgctgct gcaaggctca tctagccaag
    15781 gtcttttagc tgtaccagtg aaggctctga gtctttcgtc gaaaaaagac gcaaaacaat
    15841 gatgaaaaga atacaaaaag aaaagaggta ggataatgac aacagctatt gattgggaaa
    15901 acttaggctt tgaataccgc aaactgccat ttcgctatat atcatactac aaggacggca
    15961 aatgggacgc aggtcgctta acagaagatg ctaccctgca catctcagaa agtgcaccag
    16021 ctctgcatta tgggcaacaa gcctttgaag gcttaaaggc ctatcgcact aagaacggtt
    16081 ctattcagct atttcgccca gaccgcaatg cagctcgctt gcaggcaaca gctgaccgtt
    16141 tgctgatgcc acaggtatct accgagcaat ttattgatgc tgttaagcaa gtggtaaagg
    16201 caaatgagga ttttgtaccg ccatatggaa ccggtgctac cctttacctt agacccttgt
    16261 taattggtgt tggcgatatt atcggtgtta agcctgctaa cgaatatata tttacagttt
    16321 ttgccatgcc tgttggcaat tactttaaag gcgggcttgc gccaaccaac tttattgtat
    16381 ctgaggatta tgatagagca gctccttatg gtactggagc tgccaaggtt ggtgggaact
    16441 atgcaggtag cttattgcca ggaaaggcag ctaagacagc agggtattca gatgtgattt
    16501 acctagatcc agcaactcac actaagattg aagaggtcgg agccgctaat ttctttggta
    16561 tcactgccaa caacgaattt attacaccgc ttagcccatc aatcttgcct tcaatcacca
    16621 aatactcctt gctccaatta gccgaagaaa ggcttggcat gactgccatt gagggtgatg
    16681 tgccgattaa cgatttggat cgatttgttg aggcaggagc ttgtgggaca gctgctgtga
    16741 tctcaccaat tggaggcatt cagtatcagg ataagctaca tgtcttttat agcgagactg
    16801 aggttggtcc agtgacacgt cgattatatg atgagctggt cggtatccaa ttcggtgata
    16861 tcgaagcacc agaaggctgg attgtagcta ttgattaaaa taagtgaagc ttgctattgc
    16921 aagctctttt gattttgtgt aaaatagaca aggcgaggtg aagtgatgag taaaaaagag
    16981 aaaaaaattg aactgcaatt atgcgatcaa caagtaacag tcaacaatac caagatagac
    17041 ggttatcagt tacaaattgg caagcgtgtc gttggcgaga ttgcagagct tgatggcaag
    17101 tttgctgttt taaaagacag cacagtagat gcttttttta aaacattaga gcaagcagtt
    17161 gaaaatatta ttgaaaacta taatttgaac cattaaaaat gcttaaaaag acttgtcagc
    17221 ttacaaaaac tatggtagaa tagtttttgt tattacggaa agatagcgaa gaggctaaac
    17281 gcggcggact gtaaatccgc tcctttgggt tcgggggttc gaatccctct ctttccatgc
    17341 ctaagctatt aggttcattg ttttaatgat gatattgggg tatagccaag cggtaaggca
    17401 agggactttg actccctcat gcgttggttc gaatccagct accccagtca gaggtatcag
    17461 attagcgtct gagaccgtca aggataaaag ttgttgtcat tgcgggttac cttgagaaaa
    17521 tatattgtta tcaaaagcta gcataagcta gcttttgttg gaggattttt tagaatgaat
    17581 gaatttgaag atttgctaaa cagtgttagc gaagtcaatc ctggtgatgt agtcactgcg
    17641 gaggttttga cagttgataa cggtcaagca aacgttgtta ttgaaggcac aggtgttgaa
    17701 ggcgttttga cacttcgtga attgactaac gatcgtgaag ctgatattaa tgactatgtt
    17761 aaggctggcg acaccgttga agtgcttgtt cttcgtcaag ttgtaggtaa agatactgat
    17821 acagttactt tcctagtatc taaaaaacgt ttggaagctc gtaaggcatg ggacaagctt
    17881 attggtcgtg aaggtgaagt cgttactgtt aaggggactc gtgctgttaa aggtggactt
    17941 tcagttgaat ttgaagggct tcgcggattt atccctgctt caatgattga cactcgtttt
    18001 gttcgcaata cagaaaagtt tgtcggtcaa gaatttgacg ctaaaatcaa agaagttgat
    18061 gcagcagaaa accgctttat cttatcacgt cgtgaggttg ttgaagaagc agctaagcaa
    18121 gcacgtgaca aagtcttttc aacactttca gaaggttcag tggtaactgg tactgttgcg
    18181 cgtttgacaa gctttggtgc ttttattgat cttggtggtg ttgacggtct tgttcacgta
    18241 actgagctct cacatgagcg taatgtgtca cctaaatctg ttgtttctgt tggtgaagag
    18301 gttgaggtga aggtacttgc tcttgatgag gaagcaggtc gcgtatcact atcacttaaa
    18361 gcaacaacac ctggaccttg ggatggcgtt gagcaaaagc ttgcacaagg tgatgttatc
    18421 gaaggtaagg ttaagcgctt gactgacttt ggtgcttttg ttgaggtatt acctggcatt
    18481 gatggcttgg tgcacatttc acaaatctca cacaagcgtg ttgaaaatcc aaaggacgtg
    18541 cttactgtag gtcaagaggt aactgttaag gttcttgacg ttaacgctgc tgatgagcgt
    18601 gtatcgttgt caatcaaggc gcttgaagag cgtccagcac aagcagaggg tgaaaaagaa
    18661 gaaaaacgtc aatcacgtcc acgtcgtcaa aaacgtgaag ctaagcgtga ttacgaactt
    18721 ccagaaacac aaactggatt ttcaatggct gacctttttg gtgatattga attataatac
    18781 taagagaagc tgggtaattg ctcagctttt ttatagtatt tttttagcac accaatgcat
    18841 ggagaaactg acgttttctg atagcatttt cgtaatcaat gtgctttttc aagaacattt
    18901 atggtataac taaactgtat ttgaaccatt gatgatgtca aaatatcaaa atattaaaaa
    18961 tatagtgata aaatacagat gactagaaaa taatgacatg cattttcgtc atgtgtatgg
    19021 tgtgatcttt ttaaaaaaag gattttaaaa tacccacttt tatgctatac tgtagtggta
    19081 tggttaaagg tgccaccttt agtgtaatgg atatcacgca agattccggt tcttgagatg
    19141 ggggttcgat tccctcaagg tggatagaaa cgatataaaa aagcctctgt ttgtactgcc
    19201 cccaaaaagt tggacgaata attattgaaa ggatttagtt ctgtattgaa caggactaag
    19261 tccttttagt ttagttttga ttcgtttatt gttgtagtaa aagatgtatt cagtgattgc
    19321 ttgttcgagc tcatccagtg agtggtagga tttctcaaag ccatagaaca tctctgactt
    19381 taaaatgcca aagaaggatt ccatcatccc attatcaggg ctgttaccct tgcgagacat
    19441 tgatggacga atgccctttg attctaaaaa atgatgatag gactgatgct ggtattgcca
    19501 cccttggtca ctgtgaagaa tcgttccgtg ataggattga tctggaaaag ccttctcaag
    19561 catggtttga acctgtttta agtctggaga cctagatagt gtgaaatcaa taatctcact
    19621 gttgtaacca tcaagaacag gcgctaaata aagtttttca tcgttgtttg gtaaagcaaa
    19681 ctctgtcaca tcggtataac atttttcata tggcttagca gcttcaaact ggcgttgaat
    19741 cagattatca gccttcttac ca
//
LOCUS       DARYSY010000040        19450 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYSY010000040 DARYSY010000000
VERSION     DARYSY010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19450
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(51..2054)
                     /locus_tag="TVR04_001375"
     CDS             complement(51..2054)
                     /locus_tag="TVR04_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1270054.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTV
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLGTDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQVQDYTITPGREVGDFRFVIIEERVSYARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2181..3797)
                     /locus_tag="TVR04_001376"
     CDS             complement(2181..3797)
                     /locus_tag="TVR04_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1270055.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPDHRQTLLFSATMPAPIKEIGVKFMKDPEHIQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNDYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4213..5757)
                     /locus_tag="TVR04_001377"
     CDS             complement(4213..5757)
                     /locus_tag="TVR04_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1270056.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTEEQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLIVGKNQFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5926..6621)
                     /locus_tag="TVR04_001378"
     CDS             complement(5926..6621)
                     /locus_tag="TVR04_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1270057.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSIMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLIGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EDNQLELKLSKER"
     gene            complement(6705..8090)
                     /locus_tag="TVR04_001379"
     CDS             complement(6705..8090)
                     /locus_tag="TVR04_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1270058.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIAVLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNQEDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKPS"
     gene            complement(8329..9375)
                     /locus_tag="TVR04_001380"
     CDS             complement(8329..9375)
                     /locus_tag="TVR04_001380"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1270059.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPIFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
     gene            complement(9523..10119)
                     /gene="recR"
                     /locus_tag="TVR04_001381"
     CDS             complement(9523..10119)
                     /gene="recR"
                     /locus_tag="TVR04_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1270060.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRIL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            complement(10131..12185)
                     /locus_tag="TVR04_001382"
     CDS             complement(10131..12185)
                     /locus_tag="TVR04_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1270061.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELRVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHETREIKTSRSGEVISDKIVEKGQVGRNLKLTVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            complement(12297..13067)
                     /locus_tag="TVR04_001383"
     CDS             complement(12297..13067)
                     /locus_tag="TVR04_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1270062.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLSKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKSKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWMDFVTNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            complement(13206..13745)
                     /locus_tag="TVR04_001384"
     CDS             complement(13206..13745)
                     /locus_tag="TVR04_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270063.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            complement(14140..14661)
                     /locus_tag="TVR04_001385"
     CDS             complement(14140..14661)
                     /locus_tag="TVR04_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1270064.1"
                     /translation="MKAKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSSALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASRAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            complement(14770..15465)
                     /locus_tag="TVR04_001386"
     CDS             complement(14770..15465)
                     /locus_tag="TVR04_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1270065.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            15708..16643
                     /locus_tag="TVR04_001387"
     CDS             15708..16643
                     /locus_tag="TVR04_001387"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1270066.1"
                     /translation="MVSTATKIATFAFDNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNYGYQYYLDLVIEMQKDQTSKHHFLSVV
                     GMSAEETEAILTAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDHLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAATIFNQYPLAFVNCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNPSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQK
                     GPAIFKRVTKELQDIMAEKGYKTLDDFRGQLQYKP"
     gene            complement(16691..16864)
                     /locus_tag="TVR04_001388"
     CDS             complement(16691..16864)
                     /locus_tag="TVR04_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270067.1"
                     /translation="MPITVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            17233..18126
                     /locus_tag="TVR04_001389"
     CDS             17233..18126
                     /locus_tag="TVR04_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270068.1"
                     /translation="MTNHQLGKTFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCDPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLYGIKDMTTAISIFESLDCPHLA
                     QNYQKDFERFVTPSNLICKKT"
     gene            18181..19389
                     /locus_tag="TVR04_001390"
     CDS             18181..19389
                     /locus_tag="TVR04_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1270069.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYGNSSWIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISHAFSGTAFRAYVVTLVEKERLVHFNAQLEIISQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASFLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGLLLITAMALLKLPVIVIVLGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMVTASLAYYCNY
                     RQSSKKKPFI"
BASE COUNT         5848 a         4606 c         3622 g         5374 t
ORIGIN      
        1 tctttttatt agtttagctt aaaaagcgat cagaataagc caagccttac ctaggccttt
       61 tcatcttttg tacacgcttt gatttccttg attggaagct ttaagacatc tgataagagt
      121 aaaggaacaa cctcaactgt tgcctcagaa tattgcaagc caaaccagcg cataggactt
      181 gctgtcacat gcttgatact agcctttgtc tgcatgacaa aacgttccag agtactcagc
      241 tgccttgcat atgacacgcg ctcctcaatg atcacaaatc taaagtcacc aacctctcgg
      301 cctggtgtaa tcgtgtaatc ctgaacctgc ttaggcagac ggccactctc catcaaatcc
      361 tgaacaatcg ttctaaggta acgcggaaca gtctgtggca ttctaaagcc aaggtagagc
      421 tctacacaaa cgatatagtc tgttcctaac atatccacct tgtaggtcgc cgtataaggc
      481 tcatctgtca cacgaacatt gacaaaccaa taaacctgcg cgcgtttagg acgcttatct
      541 aaaatggaat acagaattga gcgatcaatc agatcttttt tcatgcggtt ggtcaagtaa
      601 acaacattgg tctgatacaa atcaaagcga agatcatctc taaggagctt gatttgatgc
      661 ttgtaatcat ttaggctcaa ggacttaaca tatttagcaa caatcacggt tccagcatgc
      721 caaatcacca taacaaagac aatggcaaga gctaaaacaa caacaacata gcccccatgc
      781 ataaacttaa ctgcagatgc taaaaagaaa ataaactcaa taaaggcaaa aaaagccatg
      841 agcagactag ctaggagcgg ctttaccccc tccttaataa ggtaataggc taagagaatc
      901 gttgtcatca gcatggtaat cgtgatggca aggccatagg cagcctccat atgcgctgat
      961 gttctaaaat acagcaccgt acaagacgtt accgcaaaca agctccagtt aatgacaggg
     1021 atgtatagtt ggcctaggtt ggcacctgga taggtaatct taaacaacgg aaaaatcttc
     1081 aagcgcatag cctcagaaac caaggtaaag gaacctgaga ttaaagcctg cgaagcaata
     1141 atggctgcta gagttgctag aataacaaga taaacccgta atccctctgg aacactagca
     1201 aagaagggat taagcgcaat gcctgagtcc ttatgcgcta aaatccaagc tgcctgacca
     1261 caataggata agatgataca aaccttaaca aagggccagc tagcataaat atttcctcga
     1321 ccgacatgac ctaaatcaga ataaagagct tcagcaccag ttgtcgctaa aaaaatagag
     1381 cctaaaatga aaataccccg atgattttcc ggactaacca ataagtgcag cgcataatag
     1441 ggattgatag cctttaggat ttccaaatgc tgtaagctat tcaagagacc actgatcccc
     1501 aaaacgctaa accaaaccag catgactggc ccaaataatt taccaataac acccgttcca
     1561 aagcgctgca ggccaaacaa gaccatcaat atcagcaagg tcgttaggat cacattggtc
     1621 tgattctggt aaatactgct gagctcagga acagccttta agccttcaat ggctgatgtg
     1681 accgtaacag ctggtgtcaa ggcaccatct gataagagcg ttgctccccc aagcatagct
     1741 ggaatgatta accaccttga catccttcta actaaggtaa agagtgaaaa aatccctccc
     1801 tcatgatgat tatcagcctt taaagcaatc aaaacatact tgattgtcgt taccaaggtt
     1861 agagtccaaa taatcaagga tactgagcct aaaataaaag cttcagacac ctgtgaaagg
     1921 ccgccttgat tgtcaaccaa cgactgcatg gtatacagtg gacttgtgcc aatatcacca
     1981 tagacaattc ctagtgcaat aataaaacct gcctttgttg ctttatcaaa ggcatcatga
     2041 tgggcattag acatcccaat gttcctccta agacttaatc atgccaaatg gactgagacc
     2101 attatagcaa aatctataac aaaatcaata ttttcagaaa attaaaaaga gagctgacaa
     2161 tcatcagctc tcttgaaact ttagttccct ttatgacgga taataaatcc agacgtctta
     2221 gcttcgacag ccttgccctt cttgtgcagg tccttgttag agcgtttttg ctttcgctta
     2281 aagtcatagc taccactgct atcatgactg tcacgtttat cacgccttgg acggcggtca
     2341 ccatcataat catttctttt ctcatgacga tagccacctc gacggttatc acgaccgcta
     2401 cgactacgat tgccacgacc tgtcttgcca tttttattgc catgaccacc accaacgtac
     2461 ttgaacggta atggcttttc acgcgcaatc tcaacctctg gtaaggtatc tggatcttgg
     2521 acggtcaagc tcaggatata gagtgctagc tcctctgggg taaactctgc tgccaatttc
     2581 atcgcatcgc ccttaaattt ctcaaagttt gagcgaatag catcatctgc aaaatcacgc
     2641 tcaatttttt tgagggcaac ctttttctta gcctgaaagg cttcctctgc cgtagctggc
     2701 ttgagtggct tcatgcgctt cttagtcagg tgctcaatca tggtcagata gcccatctca
     2761 tttggtgaga caaaggtaat ggattcccct gacttacctg cacgaccggt ccggccaata
     2821 cggtgcacat agctttctgg gtcctgggta atgtcgtaat tgtacacatg agtaacgcct
     2881 gaaatatcaa gcccgcgcgc agcaacatca gttgccacta aaatatcaag ttgatcattt
     2941 ttaaagtccc gtatgacacg aaggcgctta ttttggtcaa ggtcaccatg tatcccttct
     3001 gcgcgaaagc cacgtaattt caagccacgc gtgatttcat caacacggcg ctttgtgcga
     3061 ccaaatacaa ttgatagctc tggctgctga acgtccatca gacgtgtcat ggtatcgaat
     3121 ttttcttgct ccttaacacg cacatagtat tgatcaacat tcacatttgt taattccttg
     3181 tttttaacct gaatgtgctc agggtccttc ataaacttga caccaatttc cttgattgga
     3241 gctggcattg ttgctgaaaa tagcaaggtt tgacgatggt cagggacacg actaataatt
     3301 gcttcaatgt cctctaagaa tcccatattc agcatttcat cagcttcatc taaaatgagt
     3361 gtctcaacat ggtctagcct caaggcctta cgcttaatca aatctaatag acgtcccggt
     3421 gtcccaacaa cgacatgtgc cccagatttt aaggccttaa tttgcttttc aatgcttgag
     3481 ccaccatata ctgagcgaac cttgacgcct ttatcacgac caaaacggaa cagctcttcc
     3541 tgactttgga cagccagctc acgcgtcgga gcaatcacca atgcttgaat ggtgttgtca
     3601 gctgtacgaa tcttattcag agttggtaga ccaaaggctg ctgtttttcc tgttcctgtc
     3661 tgagcctgtc cgataacatc tcgtccctcc aaggctaacg gaatggtcag ctcctgaata
     3721 ggagaagctt tttcaaagcc tgctgtaaca acagctgact gaatatcttc tgataagtta
     3781 aatgctgtaa atttcaattg tttctctttt ctaaaaaggc agtgcgaagc tgccttataa
     3841 accttttaat attgtcgttc gattaacaac ctatttagtg taacataatt aatattaaaa
     3901 agataggaaa taagccatga aagtgttttt atctcaaaat gattaacact atcaggcagc
     3961 taaattgata aaagcattac gtcttattgc tgatcggcta acagcctcaa aaaggcctcg
     4021 tcggacttgc ttacctatgc tttttatcta ctctgctaaa aagactcggc acagagacga
     4081 gccttcgcga ttccatcacc aatcttcaaa gacagcaatt aggattcctg aaagctcctt
     4141 atgccaatag cctgcctttt cttagcagca gaagcgcaaa aacggactag gttcccccaa
     4201 tccgcttagc tgctacattt ttgcttctag cttaacatct ggatatttat ctgcaaacca
     4261 acgaagcgca aagtcatttt caaagagaaa aacaggctga tcaaagcgat cccttgccaa
     4321 aatgtttcgg cttgatgaca ttcgttggtc caaatcctcc tctgaaatcc aacgaacagt
     4381 ctttttgccc attggtgtca tgatgacctc tgcattgtac tcaccctcca tacggtgctt
     4441 gaaaacctca aactgcagct ggccaactgc gcctagcatg tattcacctg tctgataatt
     4501 cttataaagc tgaacagccc cctcctgtac aagctgctca atacctttgt ggaaggattt
     4561 ttgcttcatg acatttttag gtgcaacctt cataaaaatc tctggggtaa aggtcggcaa
     4621 tggctcaaat tcaaactggt ttttaccaac aatcaaggta tctccaacct gataagtccc
     4681 tgtatcgtag accccaataa tatcgccggc aactgcattt tggacatttt cacgagattc
     4741 agccataaac tgagtaacat ttgacagctt aacgctttta cctgtacgag acagctttac
     4801 agccattccc ttttgaaact ctcctgagac gatacgcaca aaagcaatac ggtcacgatg
     4861 cttaggatcc atattagcct gaatcttaaa gacaaagcct gaaaaatcct gattgagagg
     4921 atcaatcatc tgctcctctg ttgttttatg cccatgaggc tccggagcaa aggctaaaaa
     4981 ggtatctaaa aaggtctgca ccccaaagtt tgtaagggca gagccaaaga ataccggagt
     5041 cagctgacca tctaaaatag cctgctctga aaaatcatta cctgcctcct ctaagagctc
     5101 aatatcttca agcacctgct cataaaaagg gttgctggca aaaatccttg ccccctcctc
     5161 taaatcagca aaccgctgct ctcccttata gagctccaag cgcttgttgt gcaaatcata
     5221 caaaccttca aaagcccgtc ccataccaat tggccagttc ataggataag aagcaatccc
     5281 aaggacctct tctagctcct ccaacaactc caaaggctca cgtccatcac gatctaattt
     5341 attaataaac gtaaaaacag gtatgttacg atgcttaaca acctcaaaga gctttttcgt
     5401 ctgtgcttcg atccctttag ccgaatcaac aaccatcaca gcagcatcaa ctgccattaa
     5461 ggtacgataa gtatcctctg aaaagtcctc gtgaccaggt gtatctaaaa tattgatacg
     5521 cttaccagca tagtcaaact gcatgactga tgatgtgact gaaatcccac gttgcttttc
     5581 aatatccatc caatctgact tagcaaattg accagatttt tttcctttaa cggtcccagc
     5641 ctcacgaatc tcaccaccaa aataaagtaa ctgttcggta atagttgttt taccagcatc
     5701 tgggtgactg ataatcgcaa aggttcgacg ctttttaatt tcttctgtaa ttgacattct
     5761 tttttcctta tttgttcaca ttgcagagca agactctgat taatagcttc aagtcacacg
     5821 tcacagttat gtctacatga tctcactcct aaatactgat atgataaaaa gagctgctag
     5881 agcagctcct ttattatagc tgattcgaag cgctttttca acgccctatc tttctttaga
     5941 gagcttcagc tctaactgat tgtcctcact aaatctcaca tagataagct cgatcagctt
     6001 aattaaacca gtcaacccca ttgtcacaat gacaaaattc ataagcaggt gatgcgtatg
     6061 aataatcgga atatccatca caaagccgta atttcccttt gttgccaaat tgatcaatac
     6121 taaaacaaaa ttaatggttg ccaagtaacg gcaaacaagg actggcttta gctgacttgg
     6181 attgtaaaac cgcagcaggt aaaccaagcc attgaccaaa agagcataat gccctaggta
     6241 aaaagaaata ttagccacat gccatagctg ataagggtat aaatcaggtg ataacagggc
     6301 caagaaggtc ccaccaatcc ctaaaaccat aaaaagctgc tttaagctgc tgcgatccgg
     6361 taagaaaaag atagctagca tggccattcg gcaatggtaa agcggcaaag cctctgtcaa
     6421 cggaaaacct cgcaaggcat accagctgta caaaccaatc aattggacca actgaagccc
     6481 taagaagata tagcgatacg actttagctg atagagctgc agggtcataa aaaccaaaaa
     6541 cggcgctatc ataatcgaca atagataaaa tagcaaagac acatgcggta gcccaatagg
     6601 ttcaattgca aaaaaattca taaacatccc tttctacatt ttttcattat accttaatct
     6661 taatgagagg acaagatgtt tcatgtgttt tttctgaaaa agtattagga gggcttccca
     6721 gcatgaggag ctgtcaggcg atcaaccaca tttgctagca gcatggagtg gctgcccttt
     6781 agcagcatct ggtcattagg ctcaagaata gtcaacaggt actggcacat gtcctcgtat
     6841 tgatcctctt gattattctt tttaaagaag ctaactctgc cacttggata atcttgacta
     6901 gctagcttgg ccaaggcttg aatatcatca ccgtaaaaga ccaattgatc aatacgcttg
     6961 ggatctaagc tggtaatcag ctgagaatgc aaagcaactg agtcagcgcc taattccttc
     7021 atatcagcta aaacagctat ttttttgcca ttagggttgg ccggaatggc agcaaaggtt
     7081 tccaaaatta accgcatagc agttggattg gcattgtaca catctgccaa aaggtcggcg
     7141 ccattagccg ccttgaccca ctcggttcgg tggcgtgtca gcttgacggt ttctaaagct
     7201 tctataatat cctcatcagg cacagccaag agtttaccaa cataagctgc tatcatagca
     7261 ttggttgcat tgtattttcc agttaaggga agagtgaccg gtcttggtaa gacattagtc
     7321 ctaaaggtca aggagtcctt gcactctttg atatcctcaa ccaccagctc ttgatgatcg
     7381 ccaaagcgaa tgaccatctg actatccggc aaatatggat caaggatagg atcgcccgga
     7441 gcaatcaaaa tcccgttaga atccatccca tcaacgattt gcattttccc ttcggcaatc
     7501 ttctcacgag agccaaaata ggctaagtga gcctcaccaa taagggttag cactgcaata
     7561 tgaggtctgg caattctaga gagcagctga atgtctccca tatgatcctg ccccatctct
     7621 aaaacaatct tctcagtatc ctctggcatg tgcagcaccg tataaggcaa gccaatgtca
     7681 ttattataat tgccttgggt tttataggtc ttataggctt ttgccaggac tgcttcaatc
     7741 atatccttgg ttgatgtttt accgtttgag cctgttacag caatgacgtc gacacgcagc
     7801 ttatcaatat aatactgggc taatttttga aaagcggcca agcaattctc aactagtata
     7861 taaggcctgc cactgattgc tctttctgaa aaggtagcta cggccccatt ttcaaaggct
     7921 aagtcaataa aatcatggcc atctcgctca ccctgtagcg gtaaaaaaag atcacctttt
     7981 gtgatgtttc tactgtcaaa ttcaatctga ttcagaggaa cgtcgtctaa atcagaaaga
     8041 ctattttgag catcaacaac tcttgccact tcatgtaatg ttaatttcat cttatttttc
     8101 ctcttaaaac actggttttt aaagccttgc ttatattata gcataacata ttaggaatat
     8161 tctttctatt tcactttatt cctacaggct gagccttcat agacaggctc aagctggcac
     8221 gaccaataat agacgatagg gctttaaagg ctattgacca gaaaacgtta ccaatcaggc
     8281 caaacgaaag gacagaggat tactatatct ccttccgtcc tttgtctctt atattaaatg
     8341 cccttcacgc ttttcaaaca tttcctgtgc caatctgacc agctcctcaa taagctcagc
     8401 atagctcagt cccatatgct cccagagcaa gggatacatg gaccactggg taaagccagg
     8461 catggtattt aattcattga ggtagatctg accgtcctga ccaagaaaga aatcacaacg
     8521 cgacaggcca caagccccaa tagccttaaa ggctgtttct gcgtaggtac gcatgcttgt
     8581 catagctgat tcgtcaatag ctgccggaat agccattgtg atctcattat caatgtattt
     8641 ggcctgataa tcataaaagt caacattctt gaccacctct cctggaaggg ttgatttgac
     8701 atcggtatta ccaagcagtc caacctcaat ctctcttgcc aaaacccctt gctcaatcag
     8761 gatacgactg tcatacgtca aggccaacag gatagctgca cgcagctcct cctctgactc
     8821 tgccttagaa ataccaacag atgatcccat attagccggc ttaacaaaaa tagggtagct
     8881 caacacagcc tcagtctctg ccagacacct atctaaatcc tgtccctcaa tataaacggt
     8941 ataagcaacc tgtgggatac cagctgactc taggaccctt ttggtggtaa tcttatccat
     9001 tgcaacactt gatgagagga tattagttcc cacataaggc atttttagca cctctaaaaa
     9061 gccttgaata gagccgtcct ctcccatagg gccatgtagg actggaaaaa caacagcccc
     9121 ctcctcgtag atatcactag gccttatctg ctgttctagc ctaatagtgt cattagtcat
     9181 cagcctttct gttaaggtcg gccgactaga gaattcctgt gtcttgataa actgacctgt
     9241 ctggctgata aaataggttt tcacaaaaaa tttggtgtaa tcaactgctc tcatcacgct
     9301 ctcagctgaa agcactgata cttcacgctc tgccgaacgc cctccgtata ataaaattaa
     9361 ggtttgttta gacattgata accttcccta tctgaattag actatcactt attataacaa
     9421 aaacgagctt gcttttcaaa agactctgac aaaatctgcc ttcctttatg gccttatcac
     9481 atggcataag ggctaatgac agagagctga aaatgggcta agctataatt ctgttcgatt
     9541 ttcaatcgct cgcagcaggg tcacttcatc agcatattca atgtctgatc ctactgccaa
     9601 gcctctagcc aatctcgtta ccttgatacc agcaggcttt aggatacgtg aaatgtacat
     9661 cgcagtcgcc tcgccatctg ctgtggcatt cgttgcaaca atgacctctg ttgcctctcc
     9721 agccatcaaa cgcgtgatta ggctctttag attgatgtca tctgggccaa ccccattcat
     9781 gggagaaatc aagccatgca gcacatggta atagccatga tattcttgaa ttttttccat
     9841 ggcagaaacg tccttggaat cctcaacaac taaaatgatc tctttatccc gactgctatc
     9901 tgtgcaaata tggcagggat catcatctgt caaattgcca cagatagagc aataggttaa
     9961 ttctcgctta gctgctaata aatttttggc aaaatcattc acatcctcat cagacattcc
    10021 aatggtgtaa aaagccaatc ttgtcgctgt tttaacacca atccctggta atttagaata
    10081 gctttcaatt aattttgcga ttggtatagg gtaaagcact cgtttctcct ttattggttt
    10141 ttatacatct tcatgtacaa attaatgata tccttagcca cgtattgatg tgccttggct
    10201 agagagtctg tcgcatgagg gtacatgaca gcaacagcaa tttgaggact agcactcgga
    10261 ccataggcaa caacattcaa gttaaaggta gataaagcct gaccattttt atccttagca
    10321 taggtttctg cggtaccggt tttagcacta atggtaacag gacctcctgc aagagcccta
    10381 cctgtagcat agccactacc gctattgacc acctgataaa aaccgtcctg aataatcgct
    10441 aaactatcag cagctaagtg caccttgttt aacaaggtag tctcaatagc cttacttagc
    10501 ttacctggtc ctgactggtc attatcctga taaatgcctt ctacaatgtg aggcgcaagg
    10561 cgactgccgc cattagcaat agttgagaca tattgggcca gttgcatggt tgtatagtta
    10621 tcaaactgac caaaggcctc tgtcaaaaca tttgcagtat tatattgatc tatgaggtag
    10681 ccactggatt cgccaggcaa atcaacgcca gttgccactc ccatgccaaa ttcagcatag
    10741 gctgcccgca attttttcat ggtttccttc ataccagtat tggccaaggt cataccagtc
    10801 acgtaatcct gccccatcat tctcaaggca acctgaacca tgtaagtatt tgatgaatat
    10861 tccagcgcct gactagcagt aatagggtgc tgaccgctgg taaaccaaga attaatcggc
    10921 tgggagccac caaattgaat cggctgatca atcaagacct gattcccctg aatcactcca
    10981 gcctgccagc cggcagccaa ggtcgccccc ttgacaacag acccaggtgt aaacacatca
    11041 gtaatagtcc ctaaagcgtc cttttgaagc tcaccggttt tgggattgtg tgataaacct
    11101 gccatcgcta aaattgctcc cgtattaggg ttaagcgcca cagcatagat cccttctgag
    11161 taagcagcct gaccattttt gagctctgtc tggaagtgct gattcaagat ctgctcaacg
    11221 ccctgttgaa aatcaagtgg cacggtcaac ttcaggttcc gccccacctg acccttttcg
    11281 actattttat ctgaaataac ctcaccagat ctgctcgttt tgatttctct ggtttcatgc
    11341 tttccttgaa ggacctcctc atattgcttt tccagataag aggttccaac acgatcatta
    11401 agcgaatacc cctttttaag ataggccttt gcttcttcct ttggaagacc ggcttcctca
    11461 ctagagaccc ttccaataat ggcagcaagg cttgtctcct ccacctgacg ctcccagtct
    11521 gtcccaactg aaattcctgg taattttgac ttattggcca taatgatggc aatatcctgc
    11581 tcagacaagg ctgatgtttt gagctttaca gtgctaaata cagctgctgc attcatttgg
    11641 ttaaaaatag caatgaccct tagctcttgg tctgaatagg tcaagtctgt ttccttaaga
    11701 gaggctgctg cattttgata tatttgtgct tcgactaatt tattgccaaa gcgatccacc
    11761 ttgtcctttt ggggtaaggc ttgaaccgtc ttagcataag cctctggatc tgccaaataa
    11821 taatcctttt tggctctgac tgtcacttta gcctcaggat agctaatata agcagctagc
    11881 tgatgagcca aagccttaat gtccttagcg ctagccttgg gacttctcgt ataggttacc
    11941 acgtccttga tacgattaga aactagaacc ttcccattac ggtcaaaaat ggttcccctt
    12001 ggcatagagc tttttacttt gtaaacggtt gacgctgtca gctttgcctt gtaaaaatcc
    12061 ttctcataaa tctgcatttg tgccaatctc aaaatcaggg caacaaacaa aaaaacaatc
    12121 accaaaaaaa ggagatgaat tcgcctagga atgcttgctt ttttcttttt tatccatgat
    12181 gccatattag atgcttatca actcctcctt tttaaacgtc gtttcctatt ttatcacaaa
    12241 atataaaaat aagactgaga ataaggtctc ccagtctaaa aatataacag cactaatcag
    12301 gcttccttag agtgatcata agccttgtaa taaaagagac taacaaaaat agcaccgccc
    12361 agaacattgc ccacataaac aagcgcaaag ttggtcacaa aatccatcca gctggcgcca
    12421 ccctcaaaaa tagccgccgg aataacaaag gcattggcca cactatgctg aaagccaagg
    12481 gcaacaaagg tcatcacagg aaaccaggtt ccaaggagct tacctgtcgc atcactagcg
    12541 ccatagcaca gccaaagcgc caggccaaca aaccagttac agccaattcc tgaaacaata
    12601 gcctgtaggg gagttgcagc aagcttggca tgggctacct caatgacctc ttctttaaag
    12661 ctgccagtag ctgtcagacc cagaaaatga ccaaaaacaa aggcaacgaa caaggctccc
    12721 aaaatattaa aaagggtaat caccagccaa ttggccatca agtccttgga cttaatcttt
    12781 tttgcaaaaa aggctgccga caccgccatc atgttgcctg tgatcaattc accaccagcc
    12841 atcaaaataa taatcagccc aatcggaaag gcacaagcac ccaaaatact agaaaaagcg
    12901 ccaaaggtct ccagcccact agctgcaatc ctaacataca ataagtagcc taaactaatc
    12961 atcgcaccgc caataaagcc taaaatagcc ttagacaaaa aaggctttgc aaccttatgc
    13021 tcaccaatcg taatcgtcgc ggctaatatc tgttctggtg ttttcatgac atctcctttt
    13081 gttagtatat tcacaaatgc actctttagt atagcaattt ttcaaaaaaa tgcaagcact
    13141 ttcagaaaaa agagcctcag cttgtaacag ccttggctac taaaacataa atacccacag
    13201 aaatcctagc ttgtcactga tagatgaccc ttctgcctta agaagcgcca gataaataag
    13261 gccagataaa aatccaccat accatgcagc aaagacccaa agccaacaag catcagcatt
    13321 gaccaaaaat aagaaagatc agttgctgct gttgctgtca tcagataaac cactaaaaac
    13381 tctgctaggc catgaatcac atttgcgata atcccaaaaa caaaggttct taacggtgtt
    13441 tccagccatt taggctgcct tttgagcata aaagccgcaa tagctgcaaa aagcacgtgt
    13501 gagaaagctc gcataacaat aatcatagga aatcctgcta gcaaaaagcc cagccctgtt
    13561 cctatcccca ccaagatcgc taccggaatg gatataaata tggctaaaaa caagggcaga
    13621 tgactagcta gggtaaagga agccgggcca ataataagct taatgggcat tatcatcgga
    13681 atcaagatgg caaaggccac caaaatagaa gagtaggcaa tcagttgtgt tggttttttg
    13741 gtcataatat ctccttttac tagtcgctag tataaccaaa aatgtgacag atgtcaagac
    13801 acctagcaaa tcaaaaaaca accacagcat aagctcaatc ccagccctcc tcaagcacca
    13861 aaagctaaga caaaagacag acacatctca gccattgcag caccaagccc tgcagcctaa
    13921 cagcataaaa gattatccta gcaaaaaaag taaactcaaa gctaggcttt tcaccataac
    13981 cgcagcagcc tccttccttt taacctcatt tgaggcccag ccacaaggct ttggcctcag
    14041 catctaggag ctgtcctgcg gtccctatca cctacgacaa aagagggaca ttggctatca
    14101 agccaagact aaatccctgt gaagccagct gctatcagat tattgttcac catagagaat
    14161 gcctgcagct gctagatctc tcttgatctc ttcaaatgcc tcctgatcag ggcaggacaa
    14221 aaggtgagtg tgcagaccct ctgtcaaaga cgacaataat tctgccctag aggctccgag
    14281 cttttcaata aagttattaa tatcagctga gcttttaatg ttaagcggtg ctgtcagcat
    14341 gccataaata gggtgctcta cctccacatt ggtcacaatg ccatcatgtg ctaatatcaa
    14401 ctccaactcc tgccttgtct gctcaggtcc atgctggcaa acaattctag cagaatagtg
    14461 atgactaaac aaagcacttg acaggatata tccctttggg gttgaaataa tgtcaagctg
    14521 ctgcgcccta agtaaggcaa tgtctccgac aatcacctga cgactaactc ccaatgcctt
    14581 ggctaagcta gttgctgaga tggcttcttg tgcttggctt agcctatctg taatagcttc
    14641 tcggcgttcc tttgctttca taagattccc ttcttttacc actttttaac tatcatatca
    14701 catttctggt ggaaacgcct tttttatcac caaaacaaaa aagccagagc taagtctggc
    14761 ctcacagcat tattcaccgc cgaggtagta ctcagcagta aggtttagct tgtcatcaaa
    14821 ttcaaaaaca agtggtggga agtttggaat ctccacattc ataatctcgt catctgataa
    14881 ttgcttgatg tgtttgacaa gggcacgaat agagttacca tgtgctccaa caaaaacatt
    14941 tttaccatca actaaggctg gtgcaatctt atcctcccag aaaggaagag cacgctctag
    15001 tgtcaccttc aggttttctg catctggaat aacagaatga tcaagatgag cgtaacgacg
    15061 atcagtatgt gctgaatgct catcatcctt agccatatca ggaggcaaca catcatatga
    15121 acggcgccag atatgaacct gctcatcacc aaattgctca gctgcttctg ccttgttttt
    15181 accagtcaag ccgccatagt gacgctcgtt caagcgccat gatttttcaa caggcaccca
    15241 aagctgatca gaatactcaa gtgcaagatt agttgtcttg atagcacgct taagcacaga
    15301 tgtgaaggca aggtcaaatg caatgccagc ttccttgatt aattttccag catcaatagc
    15361 ctgctgtgtt cccttttcgg acaaatcaac gtcagcccaa ccagtgaaaa ggtttgcttt
    15421 gttccattct gactcaccat gacgagcgaa aaccaatttt accattagtt aatatctcct
    15481 tattaagttt aaaggcttcc tgccttttta caactcctat tttacaaaaa ataggctaaa
    15541 aaagctagtc tattcctctc tttattgaaa atcattttgt taatatcatg aaaaaagcta
    15601 aaacctcaca aaagaaggcc ttcaagcaaa tattttgcaa aaatgccttg ctattctcat
    15661 gctctagtga tagaatagaa aaaatttgtc taaaaatgga ggaaaacatg gtttctactg
    15721 ccacaaaaat cgctacattt gcctttgata attgcctgat gaatgctgcc ggggtgtatt
    15781 gcatgaccaa ggaagaactg ctagccattg aggcctctga ggctggatca tttgtgacga
    15841 aaacaggcac cctagcccct cgacagggca accctgagcc tcgctatgca gatacagcac
    15901 taggctcaat caattcaatg gggcttccta actatggtta ccaatactat ttggatcttg
    15961 tgatcgaaat gcaaaaggat caaacaagca agcaccactt tttatctgtt gtgggcatgt
    16021 ctgctgaaga gacagaagct attttaacag ccatccaggc ctctgattat caaggacttg
    16081 tggaattaaa cctgtcatgc ccaaatgtcc caggcaagcc tcagctggcc tatgactttg
    16141 aagccacaga tcacctccta aaaaagatct tctcctatta caccaagcct ctaggcatca
    16201 agctacctcc ttattttgat attgtccatt ttgaccaagc cgcaaccatt ttcaatcaat
    16261 accccttagc ctttgttaac tgtgtcaatt ctattggcaa tggtctggtt attgatgacg
    16321 agcaggtcgt catcaagcct aaaaacggct ttggtggtat tggtggtgat tacatcaagc
    16381 caactgccct ggctaatgtt catgcctttt accaacggct taacccttcg attcagatca
    16441 ttggcacagg tggcgtcaaa acaggacgtg atgcctttga gcatatccta tgcggcgcag
    16501 ctatggtaca aattggaaca gcactgcacc agaaaggacc agctattttt aagcgtgtca
    16561 ctaaggagct acaagacatc atggctgaaa agggctacaa gacactagac gattttcgtg
    16621 gccaattaca atacaagcct taaaaaatga gtctgagacg aaacatctca gactcatttt
    16681 tagctttatg ctaaaaggga aaggcttttt ttgactcctc ttggtcaatc gcctgcttgg
    16741 tttctttttg atcctgttct agcttcttta gttgtttttt ctcaaatgct ttataaaagc
    16801 atagaaaaat aatgacctta accaccgaaa agatagcaag tccaaggatg acagttattg
    16861 gcatagctct actttcattt ttaatgttct cactattatt ataagctctt tttccctttc
    16921 aagcaagctt taatagcagc aggtcatgac gcaggcatga agaaaatgcc tatacccatt
    16981 ttccagctac aggcattgtt caacatattt ttagcatgtt tacagtgtca catcatcagt
    17041 ttcttaattt taatctgata ataccgtaca aatgttgcga aaaagaccat atcaatgata
    17101 aaaatagcta tcaaaaagtg taaatgcttt catgcctttg tggcggcagc agacaagttt
    17161 caatgtttgc acatacggga aaatacagca acagaagcct tacatgatat actcattaga
    17221 ggaggaaaaa atatgactaa tcatcagttg ggaaaaacat ttcgcagcat tagacaaaac
    17281 agaaatatca ccttacagca gcttgccagt aaagacgtgt ccttgtctca gttatcccgc
    17341 tttgaacgcg gcgaatctga tctatcagta acaaagtttt taacagcttt agacagcatg
    17401 caggtggaaa tcagcgaatt tatggacata gctgccaact tcaaacagac agagcaaatt
    17461 caattcatgt cgcagctgat caagctggaa tatgcacgcg atattgaggg attcaagcaa
    17521 ctgcaaaagc aggaattggc aaagcaccaa gctgatcctg ataccaatcg ttactattta
    17581 aacagtatat tactccaagg ctttatctgt aaatgcgatc ctagcattcc ttttcctaag
    17641 gcttatcttg atgaggtcac tgactacctt tttaggactg aaagctggca tatctatgag
    17701 ctgattttaa ttggaaatct ctatcttttt attgatattc ccctgctaga taaaatggga
    17761 aaggaaattc taaacaatca tacctactac gaaagcattt caaccaataa gcatttggtt
    17821 accataaccc ttctcaatat ttgggaaacc tgtatccacc gacatcagct tgactatgcg
    17881 cgctattatc aaaagcagat actagcccta ctcaataatg aaaccaagct atatgaaaaa
    17941 accatctttt tatttttaaa gggcttagag gactaccaaa gagggcagtg tttatatggt
    18001 attaaggaca tgactactgc tatttccatt tttgagagtt tggattgtcc tcacctggcg
    18061 caaaattacc aaaaggattt tgaaaggttt gtaacaccct ctaaccttat ctgcaaaaaa
    18121 acataaagcc ctaaaaaact gatttataat aaaaccacat aattttttgg aggttttatc
    18181 atgcgcaaaa acgactacca gctgctcgct agtcgagcta ttaacaaaat aggaaatact
    18241 gtttacgatt atggcaacag cagctggatt gctggactcg gagcaactgg ccgacaatat
    18301 ttgggttatt atcagctagc tgaaggcctt atctcactca tcttaaatcc tatcggtggt
    18361 gccattgctg atcgttataa acgacgacaa ttgttattgt ggacagatgc tatcggagct
    18421 atcagctgcg gacttttagc cctgatagct aaccctacta tcatgcttta tgggcttatc
    18481 actgttaatg ctcttttagc aatatcgcat gccttctccg gaactgcttt tcgagcctat
    18541 gtggtcacac tagttgaaaa agaaagactt gttcatttca atgctcaact agaaatcata
    18601 tctcaaatca tcagtatttc ctcaccgatg cttgcttttt tagtgatgga ttgctttggc
    18661 atcaaaacag ccctggctct agatagcatt agctttctgt tgtcctttct atgtctatat
    18721 acaatcaagg acaaggaaag gcacatcact aagcagagca gccaaggcaa caggcttcag
    18781 cttttaacag atattaagga ggggctgcaa ttcatctacc atgacaatga cattttttct
    18841 ttgttgatta ttgcttctct tgtgaatttc tttattgctg ccttcaatta tttaatacct
    18901 ttttcgaatc agctgctagg cagccaatca agctatgcta gttttctttc gatgggagct
    18961 ttaggggcta tcttaggagc ttttatggct aacaagctct ttaaaaataa tcagcaaagc
    19021 ttactcttat ctctaggcct tagtggtcta ggtctgcttc taataacagc tatggctctc
    19081 ttgaagcttc cagtcattgt gattgtcctt gggaatttat ggtttgaatg ctttttaaca
    19141 atctttaaca ttcacttctt ttctatcgtt caaaaaaagg ttcctgaggc attgctagga
    19201 cgagtcttta gctcaatcgt cacaactgct attctcttaa tgccactggc aactaccatc
    19261 atgacctgca ttccagcctc tgttcatcta gcaacctttg ctgttattgg aataggtatc
    19321 atggtgactg ccagtcttgc ctactattgt aactataggc aatcctccaa gaaaaagccc
    19381 ttcatctgag tcagtcattg gtgttagaaa tcccttgtaa cattatctca gaaaaaaatc
    19441 aaatagcttg
//
LOCUS       DARYSY010000041        18946 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYSY010000041 DARYSY010000000
VERSION     DARYSY010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18946
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            69..1070
                     /gene="ccpA"
                     /locus_tag="TVR04_001391"
     CDS             69..1070
                     /gene="ccpA"
                     /locus_tag="TVR04_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1270070.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            1140..2615
                     /locus_tag="TVR04_001392"
     CDS             1140..2615
                     /locus_tag="TVR04_001392"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1270071.1"
                     /translation="MSHQLLMQAFEWYLPADAKHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFDQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQPLTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDARSNEIGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQLLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            2911..3909
                     /locus_tag="TVR04_001393"
     CDS             2911..3909
                     /locus_tag="TVR04_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1270072.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASHQHLVLRDIPVYEGWIDQ
                     DSAELAKDTSGFVAALRRILSGESNKTEAGYRVAKGRSLDRIAHQLVAIYQKVMEL"
     gene            3911..5245
                     /locus_tag="TVR04_001394"
     CDS             3911..5245
                     /locus_tag="TVR04_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1270073.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIRKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSSGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDRMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSSSIKLVQGAIHLPKKAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            5860..7806
                     /gene="thrS"
                     /locus_tag="TVR04_001395"
     CDS             5860..7806
                     /gene="thrS"
                     /locus_tag="TVR04_001395"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1270074.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVMP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVA
                     KTLRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAIAEFVDNILADIARKSRPAEG"
     gene            8088..9080
                     /locus_tag="TVR04_001396"
     CDS             8088..9080
                     /locus_tag="TVR04_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1270075.1"
                     /translation="MAMIEVSQLQKQFKKSMKSPGLKGALQSFINPQYQTFEAVKNLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDKVFHKRMDFLNEVLELNDFIKDPVRTLSLG
                     QRMRADIAASLLHHPKVLFLDEPTIGLDVSVKDNIRKAIMQINQEEETTILLTTHDLS
                     DIEQLCHRIFMIDKGQEIFDGTIEQLKQEFGKTKSLSFELYPNQDHIASSFEGLSHIS
                     VRRQDLLLDLQYDVSYYQTADVIQKTLAEFSVRDLKFKEVDIEDIIRRFYRKEL"
     gene            9082..9900
                     /locus_tag="TVR04_001397"
     CDS             9082..9900
                     /locus_tag="TVR04_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEL1270076.1"
                     /translation="MTSFWRRYKPFLVAGIQELITYRVNFFLYRAGDVLGAFVAFYLW
                     RAVFDASHQSLIRGFRLSDMTLYIIMSFVTGLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFATSFLFMELGFRLMVFLSVGLPFLFLLFGMRLAAGVPFWQVTGNLLAFLMSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNSLVAFMSGSLIPLVFFPKLIADLLHLLPF
                     SSLVYTPVMIVIGKYSIAQICQALALQAFWLLVMVLASQLIWKKVQSHLTIQGG"
     gene            9902..10687
                     /locus_tag="TVR04_001398"
     CDS             9902..10687
                     /locus_tag="TVR04_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270077.1"
                     /translation="MTKLARMHMIFIRQYLKQIMEYKADFVIGVLGVFLSQGLNLLFL
                     TVLFQHIPALEGWSFSQIAFIYGFSLVPKGLDHLLFDNLWALGQRLVRKGEFDKYLIR
                     PISPLFHVMVETFQVDALGELLVALILLAATASSIDWTATKLFLFIVTIPFAALIYTS
                     LKIATASISFWTKQSGAVTYIFYMFNDFAKYPVSIYNSLLRWLISFVVPFAFTAYYPA
                     AYFLRGEHVVFHIGGVIVMSLVGLAIALRLWEMGLEAYESAGS"
     gene            10895..11033
                     /locus_tag="TVR04_001399"
                     /pseudo
     CDS             10895..11033
                     /locus_tag="TVR04_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062665.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            11186..11725
                     /locus_tag="TVR04_001400"
     CDS             11186..11725
                     /locus_tag="TVR04_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270078.1"
                     /translation="MRQLITAMVEKNQDLPRNSLVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSQALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLILDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGVLLAKGELHV"
     gene            11722..12837
                     /locus_tag="TVR04_001401"
     CDS             11722..12837
                     /locus_tag="TVR04_001401"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1270079.1"
                     /translation="MIDVYIQKGLRTPIGLAGRQFARVRPELLGAQLINALVKAYKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            12827..14089
                     /locus_tag="TVR04_001402"
     CDS             12827..14089
                     /locus_tag="TVR04_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1270080.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEEEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSDFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPQLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQRSLTAVKAYLEAHLSPVQLPKRYMLLKEL
                     PLNDSGKVDSRRLSQLANKPSNAAHNTK"
     gene            14134..15150
                     /locus_tag="TVR04_001403"
     CDS             14134..15150
                     /locus_tag="TVR04_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1270081.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSVSLQLLAVASAIDD
                     RLGSPTFFAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEGMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGRFLNEMDGELVTNKGIINGASFNYGTAGKRHWELDIAPISRHDPAFRKD
                     CLAGYRAPKWLKRSWFQLSPPDFDYSYFNAKGFFSLNSKSCFALVKRQACAFRWQIWR
                     SRLF"
     gene            15359..16069
                     /locus_tag="TVR04_001404"
     CDS             15359..16069
                     /locus_tag="TVR04_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1270082.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            16062..17414
                     /gene="vicK"
                     /locus_tag="TVR04_001405"
     CDS             16062..17414
                     /gene="vicK"
                     /locus_tag="TVR04_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1270083.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            17418..18227
                     /locus_tag="TVR04_001406"
     CDS             17418..18227
                     /locus_tag="TVR04_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1270084.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     TQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         5066 a         3712 c         4573 g         5595 t
ORIGIN      
        1 aagtggttac aaatcatgct aaaatacttt ttgaaagcgt cattttcagt tagaaaggaa
       61 gatgaagaat gaatacagat gatacaatca cgatttatga tgttgctcgc gaagcgggag
      121 tttcaatggc gacagttagt cgagttgtaa atggtaacaa aaatgtaaag gaaaataccc
      181 gcaaaaaggt cttagaggtt attgatcgtc tcgattatcg tccaaatgct gttgctcgtg
      241 gtcttgcaag taaaaagaca acaacagttg gtgttgtgat tcctaatatt gcaaatagct
      301 atttttctat cctggcaaag ggaattgatg atattgctgc tatgtacaag tacaatatcg
      361 ttcttgcttc aagcgatgag gacgacgata aagaggtcaa tgttgtgaat accctctttg
      421 caaagcaggt tgatggcatt attttcatgg gacatcactt gactgacaag attcgtgcag
      481 agttttctcg ttcgcgtacg ccaattgttc tggcaggaac ggttgatctg gatcatcagc
      541 tgccaagtgt taacattgat tataaggcgg ctgttgctga tgttgtggac attttagcta
      601 aagaccacca aagtattgcc tttgtttcag ggccgctcat tgatgatatc aatggaaagg
      661 tgcgtttggc tggctacaag gacggactca agaagaacaa gcttgatttt aaagagggtc
      721 tggtgtttga agccaactat tcctataagg aaggctttga gctggctcag cgtgtgatca
      781 attccggagc gacagctgcc tatgttgcag aggacgagct ggcagcaggc cttttgaatg
      841 gtctttttga agctggtaag cgtgttccag aggactttga gattatcaca agcaatgatt
      901 ctccagtggt tcagtacaca cgtccaaatt tgagctctat cagccagcca gtctatgact
      961 tgggtgctgt tagcatgcgt atgctcacta agatcatgaa taaggaagaa ttagaagaaa
     1021 aagaaatttt attgaaccat ggcattaaaa agcgtgggac aacaaaatag ttctgcctgt
     1081 ttaggcagct ttgaggacaa gctgggagtt ttctggtttg tcctttttag gaggttaaga
     1141 tgagtcatca actattaatg caggcctttg aatggtattt acctgctgat gcaaagcatt
     1201 ggcaaaggct gaaaagcagt attcctgagc tgcagcagct aggtgttagt cagctgtggc
     1261 tgccgcctgc ctttaagggc actagctctg acgatgtggg atacggtgtt tacgatttgt
     1321 ttgatttggg agagtttgac caaaatggga ctgtcagcac aaaatatggc agcaaagagg
     1381 attatttgca gctgattgca gccctaaaag aggcaaaaat aaagcctatt gctgatgttg
     1441 tgctgaacca taaggctaat ggtgatcaca aggaacgctt ttctgtgatc aaaatgaatc
     1501 cagagaaccg tcagcagcct ctcacagagc cctatgagat tgaaggctgg acaggctttg
     1561 attttcccgg cagacaaaat acctataatg actttaaatg gcactggtat cattttacgg
     1621 gattggatta tgacgccagg tctaacgaga taggtattta catgatcacc ggtgataaca
     1681 agggctgggc caatgatgag cttattgatg atgagcatgg taattttgat tatctaatgt
     1741 acaatgacct ggatttcaag caccctgagg taatccaaaa tttacaggat tgggccaagt
     1801 ggtttattga gacaactggt attgagggct ttcgcttaga cgctgtgaag catattgatt
     1861 cttattttat tcagaccttt atcaatgata ttcgtaccca actaaagcct gatttagagg
     1921 tttttggaga atactggaag tctgatcagg aatctatgga ggattacctc gaagcaacga
     1981 aggctcagtt tgctctggtt gatgttgcgc tgcatatgtc cttttttaat gctagccagc
     2041 aaggagctga ttttgatttg accactatct ttgatggcag tcttgtggct agtcggccgg
     2101 accttgctat tacctttgtg gaaaaccatg acacccaaag agggcaagcc ttagagtcaa
     2161 ctgttgagga atggttcaag cccttagcct atggcctgat tcttttacga caagagggca
     2221 agccctgtct tttttatggt gattattatg gtatttctgg agactaccct cagcaaagtt
     2281 ttaaggaggt tatcacaaaa atggcagagc tcaggcagca gctggtctat ggggagcaga
     2341 ttgattactt tgatcatgcc aattgtatcg gctggacctg cttaggagat gatcagcgtc
     2401 ctcagctttt ggcagttgtt ttgtctaatg gcgatgcagg ctggaagcac atggaggttg
     2461 gtcaagccta tgctggtcaa gttttttgtg atttcttaga caattgtcag gagactgttg
     2521 ttgttgctga ggatggctgg gcagatttca aggtagaggc aggctctatc tcagcctggg
     2581 tgttacaaaa agcacagcca aaagaagaag cttagctgat aggctgaatt aatcagaaga
     2641 aaaggccagg tcttgcaggc tttttggcca gtgagaaagg tgggaggctt tcttgaaagg
     2701 gctaatacgt gagccttgag ctggagcttt cacgatcttg gtctagctga tattaccaag
     2761 atcagccatt tgatgacagc aaaagcagga cttaaaagca tttttgagat gagtataggg
     2821 gtagaagaag ccttacccta aaatcagtct cagggctgat ttttaactct cttagtgaaa
     2881 aataccataa aataggctat aatagacagt atgaaagtct tattgtattt agaagcagaa
     2941 aattatttaa gaaaatcagg tatcgggcga gcgattaagc atcaggcaaa agcgctatcg
     3001 cttgtgggac aggagttcac cactgatcca aaggacgact atgatttggt tcatctcaat
     3061 acctatgggc ttaaaagctg gcttttgatg tcaaaggctc aaaaggccgg taaaaaggtg
     3121 atcatgcatg ggcattcgac agaggaggat tttagaaatt cctttatttt ttcaaatcta
     3181 gtgtctcctt tattcaaagc ctatctctgc cgcttttaca ataaggcgga cgccattatc
     3241 acaccgaccc cttattctaa agccttgatt gagcattacg gggttaagac tcctattttt
     3301 gcagtatcta atgggattga tttggagcaa tatggtgcta atgctgacaa agaagctgcc
     3361 tttcggcgtt attttaacct taaagagggt gagaaggtag tcatgggagc ggggcttttc
     3421 tttcttagaa aagggattga tgagtttgtt aaggttgctg agatgatgcc agatgttcgg
     3481 tttatctggt ttggtgatac caataaatgg gttattcctg ctcgtgtccg ccagattgtc
     3541 aacggtaagc accccgataa tgtgatcttc cctggttata tcaagggaga tgtgtatgag
     3601 ggggctatga ctggggctga cgcctttttc ttcccaagtc gtgaggaaac agaaggtatt
     3661 gtagtcctag aagccttagc cagccatcag caccttgttt tacgtgatat accagtctat
     3721 gagggctgga ttgatcaaga cagtgctgag ctggcaaagg atacctcagg ctttgttgca
     3781 gccttaaggc gcattctttc aggggaaagc aacaaaacag aggccggcta tcgtgtcgcc
     3841 aaggggcgca gccttgatag aattgctcat caattagtgg ctatttatca aaaagtaatg
     3901 gagttataag atgcgtgtag gtctatttac agatacctat tttccacagg tttccggagt
     3961 ggctaccagt attcgcaccc taaaggagga gctggaaaaa gaggggcatg aggtctatat
     4021 tttcacaaca acagacaagc atgttaagcg ctttgaggat ccgaccatta ttcggttacc
     4081 aagtgttcct tttgtgtcct ttacggatcg tcgtgtggtt tatcgtgggc tcatttcctc
     4141 ctacaagatt gctaaggaat atcatttaga cattatccat actcaaacag agtttagctt
     4201 aggtctgctg ggcaaaatgg tgggcaaggc cttaagaatt ccggtcgttc atacctatca
     4261 tacccagtat gaggattatg tgagctatat tgctaatggt aagatcattc gacctagcat
     4321 ggtcaagccc ctgcttcgtg ggtatttaaa ggaccttgat ggtgttattt gcccaagtcg
     4381 gattgtgcta aatcttttgg aggggtacga ggtgaccatt cctaagcgtg tgattccgac
     4441 cggcattgca ctagagaact atgttcgtga ggatatcaga aaagaagatg tcgctgcctt
     4501 gagaaaggaa ttggccattt ctgatgatga gaccatgcta ttgagcctgt cgcgggtgtc
     4561 ttatgagaag aatattcagg ctattatcca tcagctgcca gctgttttga gtgaaaatag
     4621 caggatcaag cttgttattg ttggtgatgg tccttatctt caagccctaa aggagctggc
     4681 tgtcagctca ggcgttgagg atcacgttgt ctttactggt atgattgctc atgatcaggt
     4741 tggactttat tataaggcct gtgatttctt tatttcagcg tcaacgagtg agacacaggg
     4801 gctgacctat attgagagcc tcgctagcgg caagcctatc atcgctcatg gcaatcctta
     4861 cctagatgat ttgattacag atagaatgtt tggaacactt tattatgctg agtcagaatt
     4921 gtcagatgcg attattgacg ccattttaga aacacctcaa atgaaccaga ggctgctaga
     4981 tgagaagcgc tatgagattt cagctcagca ttttggcaaa tcagtgtaca ccttttattt
     5041 ggataccttg atttcgcgac acaataagga gacgaaaaag ctaagtctct atctcaatcg
     5101 aacagaaaag agcagctcaa tcaagctggt ccaaggagcg attcatctgc ccaagaaagc
     5161 agctaaggca actgcactga catctgtcaa ggtgctcaaa gcccctatca agctagtcaa
     5221 tgcgattcgg gactttttgg actaaggtta aataacgaaa gaagcctgca attacaggct
     5281 ttggctctgc gtgagagagc agatagccct gttttttagg acaatcattt atccaaaagc
     5341 cttggcttgt tatcttgtga actgagatga caggcagcaa gtcctgtttg ggctatccgt
     5401 caaaggcttg tggcagagtt tcagggctcc ttgtctggtt attcttgcct tgtgggcttg
     5461 gtgccgggag gtctgtggac ttatctcagc tttttaggaa aaatctcttg aattatttcc
     5521 aaatattgct ataataatca agaagacaag ttagattagg tcacaccctt ttagcgagtg
     5581 ctggttggtg agaagagcac agggtgtcta gtgtaatact ccttccttgc ttttatgcaa
     5641 acataaaacg gtggtcacga tatagccaag ttgaggtgca ggacaagagt cttttgtcgt
     5701 gcataaatga aggtggaacc acgctgattg cgtcctttgg gaggcagtca gtttttttat
     5761 gttgtcataa gcagctggag ctttgctcat ctgatcaaga gcgaagcctt gttctagcta
     5821 gcttgtttta agttctagat tgtttaaagg aggaaacaga tgattacaat cactttccca
     5881 gatggcgcgg tgcgtgagtt tgaatctggt gtcacaacct ttgagattgc tgactctatc
     5941 agcaaatctc tagctaaaaa ggccttggct ggtaagttta atggccaatt aattgatacc
     6001 acgcgcgcca ttgaagagga cggtagtata gaaattataa ctgctgatca tgaggacgct
     6061 tttgaggtgc tgcgtcattc tgcagctcac ttgtttgctc aagccgcgaa gcgcttattt
     6121 cccaagctgc atcttggtgt aggccctgcc attgcagatg gtttttatta tgatacagat
     6181 aatgctgatg gtcaaatctc taacgaagac ctgcctcgca ttgaagagga aatgaaaaaa
     6241 attgtcaaag agaactttcc atgtattcgt gaggagatca caaaagaaga ggctcttgag
     6301 ctttttaagg atgaccctta taaggttgag ttgattaatg agcatgcaga tgatgcggct
     6361 ggcttaactg tttaccgtca gggtgaattt gtggaccttt gtcgtggacc tcatgtaccg
     6421 tcaacaggtc gtattcaggt ctttcatttg ttaaatgtag ctggagctta ctggcgtggc
     6481 aatagcgata ataacatgat gcagcgtgtc tatgggacag cctggtttga taaaaaggac
     6541 ctcaaggcct atttgacacg ccttgaggag gctaaggagc gcgatcaccg taagctaggc
     6601 aaggagcttg atttgtttat gatctctcag gaggtaggac aaggcttgcc attttggcta
     6661 ccaaatggag cgacgattcg tcgcacgctt gagcgctata tcactgataa agagctggcc
     6721 tcaggctatc agcatgtgta cacaccaccg cttgcgtcag ttgagctata caagacctca
     6781 ggtcactggg agcattatca ggaggatatg ttcccgacaa tggatatggg agatggtgaa
     6841 gaatttgtcc ttcggccaat gaactgccca caccatattc aggtttacaa gaaccatgtg
     6901 cattcttatc gggagctgcc tattcgtatt gcagagcttg gtatgatgca tcgctacgag
     6961 aaatcagggg ctctttcagg gcttcagcgc gtgcgagaga tgaccttaaa cgatgggcac
     7021 ctgtttgtga tgccagagca gattcaggag gaattccagc gtgcccttca gctgattatt
     7081 gacgtgtatg aggattttaa cctgacagat tatcgcttcc gtctgtctta tcgtgatcca
     7141 aaggatacac acaaatatta cgataacgat gagatgtggg aaaatgctca aagcatgctg
     7201 aaggctgcgc ttgatgaaat gggcgttgat tactttgaag cagaaggaga ggctgccttt
     7261 tacgggccaa agcttgatat tcaggtcaaa acagcccttg gaaatgaaga aaccctatca
     7321 accattcagc tggacttctt actgcctgag cgttttaacc tgagctatat tggtgctgat
     7381 ggagaagaac accgtccagt gatgatccac cgcggtgtaa tttcaaccat ggagcgcttt
     7441 actgctattt tgattgaaac ctataagggg gctttcccaa catggcttgc accacatcag
     7501 gtgacagtta tcccaatttc aaatgaagct catattgatt atgcttggga ggttgctaaa
     7561 acccttcgtg atcatggcat tcgtgcagat gtggatgatc gtaatgagaa aatgcaatat
     7621 aagattcgtg cctctcaaac cagtaaaatc ccttaccaat taatcgttgg tgataaggag
     7681 atgcaggaca agtcagttaa tgtgcgccgc tatggcagca aagcaacgca tactgaagct
     7741 atagcagaat ttgttgacaa tattttggct gatattgctc gcaaatcgcg cccagctgaa
     7801 ggctaaaaag cagaccaagc aagctggttt tggataggct gatcaggtag aaagtggctt
     7861 gacttgcaaa acagatgaca taaaaaagct tagctttaca aaagactagg cttttttatg
     7921 attagaaaat aacgaaagcg attgcattgt ttttgtaatc atgctataat gattctcatc
     7981 tatcggctgt agtaggagct tttgtgctgt ggctgactca gtaagggtca gctgggtgag
     8041 gccttagcag ctgatggcag gaattgatta gaaatgggga atggccaatg gcaatgatag
     8101 aagtatcaca gcttcaaaag cagtttaaaa aatcaatgaa gtcacctggg ctaaagggag
     8161 cccttcaatc ctttatcaat cctcaatatc aaacctttga agcagttaag aacctgacct
     8221 ttgaagtgcc taaggggcag attttaggat ttatcggagc taatggcgct ggtaaatcga
     8281 ctaccatcaa aatgctgacc ggcattttaa agccaacatc aggctattgt cgtatcaatg
     8341 gcaaaatccc acaggataac aggcaggact atgtcaagga tattggtgtc gtcttcgggc
     8401 aaagaactca gctctggtgg gacttagccc tgcaagaaac ctatacggtc ttaaaggaaa
     8461 tctatgatgt tcctgacaaa gtctttcata agcgcatgga ctttttaaat gaggttcttg
     8521 agctcaatga ctttatcaag gatcctgttc gtaccttatc tctaggtcag cgaatgcgtg
     8581 ctgatattgc agcctcacta ctgcatcacc ccaaggttct ttttttagat gaaccaacaa
     8641 taggcttaga tgtatcggtt aaggacaata tccgtaaagc gattatgcag attaatcaag
     8701 aagaggagac gacgatcctc ttgacaactc atgacttgag tgatattgaa caactttgtc
     8761 accggatttt tatgattgat aaggggcaag aaatttttga tggcactatc gagcagctaa
     8821 agcaggaatt tgggaaaacc aagagtcttt cctttgagct atatccgaat caggaccaca
     8881 ttgcctcaag ctttgaggga ctttctcata ttagtgtgag gcgtcaggac ctgttgttag
     8941 atttacagta tgacgtgtct tactatcaaa ctgctgatgt gattcaaaaa accttggctg
     9001 aattttctgt gcgagacctt aaatttaaag aggttgatat tgaagatatt attcggcgct
     9061 tttatcgaaa ggagctgtaa gatgacaagc ttttggagac gctataagcc ttttttggta
     9121 gcagggattc aggagttgat tacctatcgg gtgaatttct ttttgtatcg tgcaggagat
     9181 gtattgggtg cttttgtggc cttttacctc tggcgagctg tttttgatgc ttctcatcag
     9241 tctttgatta gaggtttcag gctatctgat atgaccttgt atattattat gagttttgtc
     9301 actggcctgc tgacaaagtc agacagctct tttatgattg gtgaggaggt caaggacgga
     9361 tcgatcatta tgcgcctgct taggccggtg cattttgcca cctcctttct ctttatggag
     9421 cttggtttta ggctgatggt ttttctgtct gttgggctgc cctttttatt cttgcttttt
     9481 ggcatgagac tggctgctgg agtacctttc tggcaggtta caggaaacct gctagcattc
     9541 ttaatgagct tgctgctagc ttttttgatt aatttttact ttaatatttg ctttggcttt
     9601 tcagcctttg tgtttaagaa cctttggggc tctaatttgc taaagaattc tttagttgcc
     9661 tttatgtctg gcagcttgat tcccttggta tttttcccaa agctgattgc agatctgctg
     9721 catttgctgc ctttttcttc cttggtgtat acaccagtca tgattgttat tgggaaatac
     9781 agtattgctc aaatctgtca ggcgctagcc ttgcaagctt tttggctttt agtgatggta
     9841 ttggcttccc agctgatttg gaaaaaggtc caatcacatt tgacgataca aggaggatag
     9901 gatgacaaaa ttagcacgta tgcatatgat ttttattagg caatacctaa agcagattat
     9961 ggagtacaag gcagattttg tgattggtgt tttgggtgtt tttctgtctc agggcttaaa
    10021 cctgttgttt ttgacggtgc tctttcagca tattcctgct ctagagggct ggagctttag
    10081 tcagattgcc tttatctatg gtttttcctt ggttccaaag ggacttgatc atcttttgtt
    10141 tgataatctt tgggccttgg ggcaacgtct ggtgcgtaag ggagagtttg ataagtactt
    10201 gattagaccg attagtccgc tttttcatgt gatggttgag acctttcagg ttgatgctct
    10261 gggtgaattg ctggttgcct tgatcttatt agcagcaacg gcgtcaagca ttgattggac
    10321 agcgaccaag ctctttctat ttatagtgac cattcctttt gcagccttga tttacacctc
    10381 cttgaagatt gcgacagcta gtatttcctt ttggaccaag cagtcgggtg ctgtgactta
    10441 tattttttac atgttcaatg attttgcaaa atacccagta tctatttaca atagcttgct
    10501 gcgctggctg attagctttg ttgtgccttt tgcctttact gcctattatc ctgccgcgta
    10561 tttcttaaga ggtgagcatg tggtttttca tattggtggt gttattgtga tgtcattggt
    10621 aggcttggcc atagcgctta gactttggga aatgggacta gaagcctatg aaagcgcagg
    10681 atcttagacg gccttgtgat gataggctta gtaataccaa caagtcctcg gcacgatagt
    10741 cctgacccct tgtttgagcc tacttcttca ctgtcctaag atcgctttta agataatcta
    10801 gccaagccta ggccttagtt ggagtaccgt aacattcgca gcagccttta tcagctaatg
    10861 tcttagaatg ataataggtc atgcgactta tctagcgcgt gaatgacctt ggacctcgtc
    10921 tcatgcatgc cttgcttcct attccaaata aaggtgattc tgattggtct tatgcttgga
    10981 ttcctgtttt aggaccaatc cttggtgggg ttgcaggtgc cttgatttat taaatgatat
    11041 tgaacatgat gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctatct
    11101 aagccttgtt tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta
    11161 acttgttcgc aaaaggatgg ttacaatgag acagctaatc acagctatgg ttgagaaaaa
    11221 tcaggattta ccaagaaaca gccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc
    11281 agatgattat cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg
    11341 gcttgtgcta gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac
    11401 aagtgctaag ccttctaaag cagttaatag ccaagcatta gctgagcata gccatgtact
    11461 gagcgttaat caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct
    11521 tcatcaaaca gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg
    11581 gcttatttta gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc
    11641 tcctattcac ctagtgatga gagaaaaggc tatcagcctc tatcaggctg gggtattatt
    11701 agcgaaagga gagcttcacg tatgattgat gtctatattc aaaaagggct tagaacgcct
    11761 attggtctag ctggcaggca atttgctagg gtgcgtccag agctgcttgg tgctcagctt
    11821 attaatgcct tagtcaaagc atataagctg gctattgatg aggtgatctg tggtaatgct
    11881 gttgggacag gcggtaatat tggtcggctg atgaccttgt attctgactt gggagagacc
    11941 gtacctgcca taactgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc
    12001 tatgctaaaa tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc
    12061 tctttgcagc ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta
    12121 gctcagtttt caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg
    12181 gctcaggcct accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag
    12241 cgagcacaca tagctaggca gaagcattgg ttagctgata ttatattagc aatgccaggt
    12301 atgtctgatc agggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg
    12361 atacttgata aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca
    12421 gcatttttag tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt
    12481 gctggcaatc ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct
    12541 agaaacggcc tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg
    12601 attgatctgc tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga
    12661 ggcgctcttg cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta
    12721 atgcaggctt tggccttaaa gcaaggaagg tatggtttag cagccattcc agcagctggt
    12781 ggtcaagcct ttgccctgtt attggaatat cataaggact actcacatgc tatctagact
    12841 gctagcttgg gcaagccaag caccacaaag acctgctatc ctaacagacc aaaagaccct
    12901 aacctatcag gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta
    12961 tccgaccctg attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt
    13021 gcaacatggt aactacccac ttatctgtca cccaaatcta ccagaagaag agcaaaggcg
    13081 tctgtctagc tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc
    13141 tactggccgt cccaaggttt tttggcgctc ctgggcttct tggtctgatt tttttgagca
    13201 gcaaaaccag ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag
    13261 ctttacaggc aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt
    13321 tagtgatcag cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca
    13381 tttatatctc ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta
    13441 ttttgccccg tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta
    13501 ttaccaacgc tttccacagc ttgagctatt gatgttttac ggtgccagcg agctttcctt
    13561 tatcagctgg tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt
    13621 tcctcaggta aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat
    13681 tgagggcatt gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt
    13741 gattctaaag gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc
    13801 tagccttgtt cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg
    13861 tggcagcagt gcagctgatg agcatgtgat cctgtgcttg gtactaaaaa agcaaagaag
    13921 ccttaccgct gttaaagctt atcttgaggc gcacctaagc ccagttcaac tgcctaaacg
    13981 gtatatgctc ttaaaggagc tgccgcttaa tgacagtgga aaggttgata gcagaaggct
    14041 tagccagctc gctaacaaac catctaatgc tgctcataat accaaataag gaaagtcccc
    14101 taagtcccaa gcatcagctc aatgtggtat aatatggtca aaaaaggagg tcagttgatg
    14161 aagcaggata tgctagcacg ttaccaggcc ctcaagcctt acgtaagagc aggtctttcc
    14221 tcggtttctc ttcagctatt ggcagttgcc tcagctattg atgatcgctt aggctcaccg
    14281 actttttttg ccatttggca gtgtgaaaaa cagtgtcgat ctcccaagga attactaggg
    14341 cttgttctag atcttgtcgg catgccaata gagttatccg gaaggctaga ggatacgcag
    14401 gctctgctga gtcgctttta tcctgacttg ccaccggatc attgcttttg ggtggagcta
    14461 gcccagatgg ttagtcttgc ttttccggat aaggagctag cgcagcagag cgcgttagct
    14521 aagggtcttc atcagcttcg ctaccttatt tcgagccagc aggcacaata tattcgcagc
    14581 cattttagat cagagggcat gactgacgct caggcactgg ctatctttct caaggataaa
    14641 aaaggcccag ctttttggcg cagccagcct gactacacgc ttatggaatc ggctcgtctg
    14701 cataacaagc taaagcttgt caatggatta gcaagctttc ctgatcatga gatttcccat
    14761 aatattaaaa ttctgttgca tttccatacc gaatttatcc ttgatagtca agggcgtttt
    14821 cttaatgaaa tggatggtga gctagtgacc aacaagggaa tcattaacgg agcctccttc
    14881 aattatggca cagcaggcaa gaggcattgg gagctagata ttgctcctat cagccgacat
    14941 gacccagcct ttagaaaaga ctgcctggca ggctaccgag ctcctaagtg gctgaagcgc
    15001 tcttggtttc agttatcgcc accagatttt gactattctt attttaatgc taagggcttt
    15061 tttagcctca atagcaaaag ctgctttgcc ttggtcaagc gacaggcctg tgcctttaga
    15121 tggcagattt ggcgcagcag acttttctaa gcaatggatc agcagccgtt ttgcctgatg
    15181 aggtatttag agcacttttg tggctagtat agcggtcatt gtcaatttct cctaaatttt
    15241 gatataatca aaaggacata aaaaatgatt ggtcctgtct ctaaatctta tggcatagag
    15301 atgaggcagc ctagtaatta gtagcaatta atgaagagaa atgttctgag gtataagcat
    15361 gaagaaaata ctgattgttg atgatgaaaa gccgatttct gatatcatta aatttaatct
    15421 gacaaaggaa ggctatgata cggtcacagc atttgatggc aaagaggccg ttgcagtctt
    15481 tgaagaggaa aagccagatt tgattatttt ggatttgatg cttcctgaat tagatggcct
    15541 tgaggtagcc aaggaaatcc gcaagaccag ccatattcct atcatcatgc tatctgctaa
    15601 ggatagcgaa tttgataagg tgattggact tgaaataggg gctgatgatt atgtgactaa
    15661 gcccttttca aatcgtgagc tgctggcgcg tgtcaaggca catttgcgtc ggacagagac
    15721 tattgagaca gcagtagccg aagaaaatgc ctcctcaggc tctcaggagc tgaccatcgg
    15781 caatctacag attttaccag atgcctttat cgctaaaaag catggtcaag aggttgagct
    15841 gacccatcgt gaatttgaat tgctgcatca cctggcaaac catattggac aggtcatgac
    15901 acgtgagcat ttgcttgaga ccgtatgggg ctatgattat tttggcgatg tccgaaccgt
    15961 tgacgttact gtccgtcgcc tgcgcgaaaa aatagaggat acaccgagtc gtccagagta
    16021 tattttgaca agacgtggtg ttgggtacta catgaaggct tatgactaag gacatcattg
    16081 gaaacctttc tgcatttgag ctagccatac tcttattgct tgtttttgtt gctttttatt
    16141 tcattcattt agccattcgt gattatcgca atgctcggat cattcgtctg atgagccata
    16201 agataagaga tttgatcaat ggtcgctata ctgatacgat caatgaaaag gctgatattg
    16261 aattgatgga gctgtctgag cagctcaacg acctatcaga tgtttttcgt ctgactcatg
    16321 aaaaccttgc ccaagagaaa aatcgtcttg ctagtatttt ggcttatatg acagatgggg
    16381 tccttgcgac caatcgttcc ggcaagatta tcatgattaa tgagactgct caaaagcagc
    16441 tcaatttaaa tcgtgagcag gcgctggaaa aaaacattac agatttatta gacagtgact
    16501 caccttacac ctaccgagag ctggtctcaa aaacaccgat tgtgacctta aatcgtcgta
    16561 atgacacagg agagtttgtt tcgctgcggc tgcgttttgc gcttaatagg cgagagagcg
    16621 gctttatttc aggtctagtt gttgtgcttc atgacacgac tgagcaggaa aaggaggagc
    16681 gtgagcgcag actctttgtc tcaaatgtta gccatgagct tcgcacacct ttgacctctg
    16741 tcaagtcata cctagaggct ctagatgaag gcgcgctaaa ggaggacata gccccaagct
    16801 ttataaaggt ctcactagac gaaaccaatc gcatgatgcg catgatttca gatttgctca
    16861 atctatcaag aattgataat catgtgacac agctgtctgt tgaaatgacc aactttacag
    16921 cctttatgac ctctatctta aaccgctttg atttggtgaa aaatcagcac accagtacag
    16981 gaaaatccta tgaaattgtc agagattacc ctatcacctc tatttggcta gaaattgata
    17041 acgataaaat gacgcaggtc attgaaaata ttttaaacaa tgccatcaaa tattcacctg
    17101 atggtgggaa aattatcgta aacatgaaaa caacagatac ccagctaatc atttcgattt
    17161 ctgatgaggg tttgggcatt ccaaaaaagg acctgccttt gatttttgac cgtttttacc
    17221 gagtggataa ggctagaagt cgggcgcagg ggggtaccgg cttagggctg gctattgcca
    17281 aagaaattat caagcagcac cgaggcttta tctgggctaa gagtgactat ggcaaggggt
    17341 caacctttac cattgtgtta ccttacgaaa aggatgctgc tatctatgat gaatgggagg
    17401 atgatattga ttaattgatg agtgaggttg gctttaaata tagtatttta gcatcaggat
    17461 cgacagggaa ctgcttttac ttggaaacgc ccaagaagcg gttgttgatt gatgcaggac
    17521 tgactggaaa gaaaatcact agtctccttg ctgagattga cagaaggcct gaggatttgg
    17581 atgctatctt gattacccac gagcattccg accatatcaa gggtgttgga atcatggctc
    17641 gaaaatataa cctagatgtc tatgccaatg aaaagacttg gcagatgatt gatgagcgtc
    17701 atatgattgg caacctagac gtcacacaaa agcatgtctt tgaaagaggt aagaccatga
    17761 cctttggaga cattgacatt gagagctttg gtgttagtca tgacgctgta gacccacagt
    17821 tttaccgcat tatgaaggat aacaagtcct ttgtcatgct gacggataca ggatatgtga
    17881 gcgaccgctt ggctgggatc attgaaaatg ctgacggcta cttgattgag tcaaatcacg
    17941 atgtggagat attgcgagcc ggctcttatc cttggagcct caagcagcga atcttatctg
    18001 acctagggca tttatccaat gaagatggtg ccggtgccat gattcgaagc ttgggcaata
    18061 aaaccaagaa aatctatctc ggtcacctaa gtcaggagaa caatatcaaa gaattagccc
    18121 acatgacaat ggtcaatcag ctagcaatgg cagatttagg tgttggaaca gattttactg
    18181 ttcatgacac ctcaccagat accgcctgtc ccttgacaga catctagcct tatgacttca
    18241 cccctgcttg ttacagtttg acaagtaggg gtgttttcgt gaggtaaaag agctctacct
    18301 cgtccagcgt aacagacttg ctatgaaaag gtttatttgg tgctacctga ggcttgttta
    18361 tgtgtgacag gggacgctca tcttttttac tttagctatt cagcaagcaa agatctagaa
    18421 gctattgcaa gatatttttt ggcttcttac taagcaggtc aactctgtta tcttctaact
    18481 aagagtagag gctatgacaa tttagcatat atggttctct aatggtctgg ctatgtgaaa
    18541 ccgtaattgc tgttattgta gggattatgt ataatatgta tcaaaagaga gatgcttgtt
    18601 ctcggtgtta ttactttacc tataatgtcg ctgctgatct gtaaggctgc tagcgatcag
    18661 gtactagcta ctcaaattag tagctttcta gctgtttttc tcatcttttg tcctgttttt
    18721 attaaaaata atgaatttat aaagatagct ttttcaaaga atagtcttta agctgacagt
    18781 agtatcatgt ggcgattttt gtcttggttt ttgcatttat ttcggttttt ttatctttaa
    18841 ttaagttact aatattctga ttatgttagt aaaatgacat tctcataaaa tgtctaaaaa
    18901 aggctaattt gtcaaggtat tatcataagg cttgatttta taagct
//
LOCUS       DARYSY010000042        18402 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYSY010000042 DARYSY010000000
VERSION     DARYSY010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18402
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            60..1013
                     /locus_tag="TVR04_001407"
     CDS             60..1013
                     /locus_tag="TVR04_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1270085.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAVRPQLLKESDMIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVAALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1073..2272
                     /locus_tag="TVR04_001408"
     CDS             1073..2272
                     /locus_tag="TVR04_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1270086.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKKTVS"
     gene            complement(2640..3230)
                     /locus_tag="TVR04_001409"
     CDS             complement(2640..3230)
                     /locus_tag="TVR04_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270087.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTRIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLG
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
     gene            3753..5795
                     /locus_tag="TVR04_001410"
     CDS             3753..5795
                     /locus_tag="TVR04_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1270088.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELQATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELRYTRASGYTLVGDELDKHRLA
                     LAMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQACLY
                     AFIFILCRYQRRVDRVKQRPVVVSEQLDQLTALLVSEIMQQLSLRYQLFEADEAYFQL
                     LLAGCFEGEGTVSDDFFESLTAAIVDQMQGVALLSFSQSDQLKEDLKRHLIPAYYRLR
                     YGLPSDNDYTLRVKDSYSELFDLVKQSLEPLAKELDSPIPDSEIAYFVLHFGGYLKQQ
                     GKDFHRQAYRAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDESCYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQDVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGPFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASTSFEDIKTIIAEEA"
     gene            5797..6084
                     /locus_tag="TVR04_001411"
     CDS             5797..6084
                     /locus_tag="TVR04_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1270089.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAGHLGDVRILNSIIDMDELTSLVKAICQEEGLI"
     gene            6097..7440
                     /locus_tag="TVR04_001412"
     CDS             6097..7440
                     /locus_tag="TVR04_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1270090.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGFTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDINFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPAWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIVYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            7443..8300
                     /locus_tag="TVR04_001413"
     CDS             7443..8300
                     /locus_tag="TVR04_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1270091.1"
                     /translation="MALSDEKLTQVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFAQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYTIVGDGELNEGQCW
                     EAIQLAAHQQLSHFFVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRTLQASSSHKPKCIVLDTVKGQGVSVLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            8297..9229
                     /locus_tag="TVR04_001414"
     CDS             8297..9229
                     /locus_tag="TVR04_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1270092.1"
                     /translation="MTRASQEMRHVYRDFLIAANQDHPELVVLEADLSSSMATNHLDQ
                     VFGKRYVNVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFISLGYAQLSA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSKGYCLLRQGEDLVFVCSGIMVKRCLEVADRMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLKILAAD"
     gene            9780..11675
                     /locus_tag="TVR04_001415"
     CDS             9780..11675
                     /locus_tag="TVR04_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1270093.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEAKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDDIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHTYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFDIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(11875..12915)
                     /locus_tag="TVR04_001416"
     CDS             complement(11875..12915)
                     /locus_tag="TVR04_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1270094.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(13083..13853)
                     /gene="rpsB"
                     /locus_tag="TVR04_001417"
     CDS             complement(13083..13853)
                     /gene="rpsB"
                     /locus_tag="TVR04_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1270095.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEV"
     gene            complement(14314..15846)
                     /gene="ahpF"
                     /locus_tag="TVR04_001418"
     CDS             complement(14314..15846)
                     /gene="ahpF"
                     /locus_tag="TVR04_001418"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1270096.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITIEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(15867..16427)
                     /gene="ahpC"
                     /locus_tag="TVR04_001419"
     CDS             complement(15867..16427)
                     /gene="ahpC"
                     /locus_tag="TVR04_001419"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1270097.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASGLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            16775..16845
                     /locus_tag="TVR04_001420"
     tRNA            16775..16845
                     /locus_tag="TVR04_001420"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16807..16809,aa:Cys,seq:gca)
     gene            complement(16953..18026)
                     /locus_tag="TVR04_001421"
     CDS             complement(16953..18026)
                     /locus_tag="TVR04_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1270098.1"
                     /translation="MAKYRKRGDKWSYRIYYTDSQGSKREKSKGGFKTKALATAAAVK
                     AEAELNKDNNNEDITLYDFCKEWAEIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNK
                     VTHTLYQKKMNVFASKYAQETLEKFHYQIKGAVKVAVRDGLIKTNFAEGAIVKSQKEA
                     RAKEFDFLEEDEYLNLVKVTSEKYQYISYFTLYIIAVTGLRFAEVTGITWNDIDFEKG
                     FIDINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLKAFKENYYKENKLNRVLYGA
                     SNSLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAH
                     QLDKLKEKNNQVIKDIFGHLTDF"
BASE COUNT         5045 a         3527 c         4054 g         5776 t
ORIGIN      
        1 cagtacaccc ggttagtggt attcttttca tttcagtctg attttgatat gatagacgta
       61 tgaattttga aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg
      121 aaaatgattt aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg
      181 gagcccaagg agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagc
      241 taaccaagga ggagtggcgt caggcttacc agtttgtttt gatcaaggct gggaaaacag
      301 agccattaca ggccaaccac caatttaccc cagacgcgat cggttttatc atgctttata
      361 ttttggagac cttgagttca caagagtcac ttgatgtgct tgagattggc agtggaacag
      421 gtaatttagc tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg
      481 agcttgatga tttattaatt gatctatcag ctagtattgc tgaaatcatg gggtcgtcag
      541 cccagtttat tcaagaggat gctgtcagac ctcagctgtt aaaggaaagt gatatgatca
      601 ttagtgattt gccagttggc ttttatccta acgatgatat tgccagcagg tatcaggtgg
      661 ctagctcaga tgagcatacc tatgcccatc atttactgat ggaacaggcc ttaaagtacc
      721 tgaaaaaaga tggttttgct attttcttag caccggtaaa tcttttgagc agcccacaaa
      781 gtcacctctt aaaacaatgg ctgaagggct atgctcaggt tgcggccttg atcactttgc
      841 ctgaggctgt gtttggcaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat
      901 cgaatcgctt tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg
      961 ttcgtgattt tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taacggaatt
     1021 ttttgatata atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa
     1081 gacaattgca attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga
     1141 agaaaaggta ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac
     1201 tgttaaatac gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc
     1261 tgttaagcgc ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat
     1321 cacaggtgtt gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggtggt
     1381 tgatgataag gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc
     1441 gggagcagca gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg
     1501 tgtgtttgat acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc
     1561 tcaaaaatat tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa
     1621 atatgttgct gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat
     1681 tacagcccat gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga
     1741 tacctctatg ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat
     1801 tgatcctgct attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga
     1861 tgtggtcaat atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga
     1921 tatgcgtgat attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa
     1981 tatctttatc gatcgtatca agaaatttat cggacaatac tttgcagtat taaatggtgc
     2041 agatgccttg gtctttaccg cgggcatggg tgagaatgcg cccttgatgc gccaagatgt
     2101 cgtcaatggc ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta
     2161 tcgtggtgat atctcaacag cagcttcaaa ggtgaaggtg cttgtcatct caaccgatga
     2221 agagctgtgc attgcgcgtg acgttgaacg cttgaaaaaa acagtatcat aataggctga
     2281 tgatatactc ttagctcagc taatcagttt taaagagtcc aaaaaatact tttaattggt
     2341 accgacctcc aaaagttaga cttaaaggtt taacttttgg aggtcggtat tattatatag
     2401 ccaaatattc tcaagacaaa gacagccaaa aaatgagacg gtcgtaaccg tctcaaaaaa
     2461 gtctaattta attaaaaaca ttcatttatc agtctttatt ttttgttatg taaaaagtat
     2521 aggcagttat ggctgaatag aaaactagtt ttggagtaaa tgatagggat aagcgattga
     2581 aacaatatgc tattgctgta taaactgaca ttacaataat aaaataacaa atatagttct
     2641 taagcccacg catttatacg accgttattt gggtgataat ctcgagcatc gacatattgt
     2701 gctagggcat atccgacatt atagtaaatg tttattactg agaatgcagc tccaagtaaa
     2761 ccggaaataa atccggttag tacaccaagt cgttgagctg cagcttttgc agctcggcta
     2821 agtacagctc gagctgcagc tactccatgt ttggcaacgt actttccgat ggttgcatat
     2881 ccactaatta acccgcctac aataacatca aaagcccaag cgaattcatc taaggttact
     2941 ccttgcccgt cccatacact agctctaaaa gtgtatggac tcatggcttt atacgcaatt
     3001 tcacgcattt cttgttctgt taaatttgga taaagagctt ttttctcttg gattaatgta
     3061 tctaactcac tttttgaaat ttctagaggt tgtgataatt tttcttcaat tactttttct
     3121 tcctgttgaa tcctagtcac ttcactagca tatacaatgg aaggtacagt gtttgcaatg
     3181 agtagtaagg acgctatcat tgcgatgatc aattgtttta cttttttcat tttgaatttc
     3241 ctttctgaaa acgatggtga tctactaagg gttaattagc tttactcctt tctaaccaag
     3301 atggtagtta tttgtcattt aataagatat cttatagttt tattatatta ttaaaataat
     3361 aaaacacaag tcttttttgg taaccgtttt cgtggtataa taaaagatta ccggttaact
     3421 attaagtctg tgatcttgtt ttaggcttat atctagagtt atcacatgct gatgaggtca
     3481 atcagttttt ttgattattt ggaacatttt tgactgttat tactccagag agctttagct
     3541 ttggcttgga cttagaaaat catggggaca actgcttagc ggcagggatg gacttgtttg
     3601 ctctttattg atagttagga ggagctggta gcctgtttag attggcatct tgagcccaag
     3661 ggctgttgat gatgttggat aagaaattgt gcccaatggg gactagttta ttgtaaccgt
     3721 tttcgataga atgactttag aaaggaaatc aaatggttga tagcaaagca gttgtcattt
     3781 tgatgacgtt gatgacttat caagacttat cactttacga gctgagtgtt aagacaaaat
     3841 tcaccattag agagattaag gaccgtattg atgagctgaa tgagtttttg gctcagcatg
     3901 agctctcaga gctgcaggca acaagatctg gctataggat cagtcagcag cttaaggctg
     3961 agtcagatca tttgtttacg ttgattaatg ctgagcaggt ttatctttct caggcagagc
     4021 ggatcaatct tatctatctg tatacctttt gccgcaggga ttttgtttca aatagtcatt
     4081 atcaggactt tttaaaggtc agcaagaaca cagcattgac agatattaag gccttgcggc
     4141 agaagctggc agatgttgac ttggaattaa ggtataccag agcaagcggc tatactctag
     4201 ttggtgatga gcttgataag caccgattag ctttggctat gattgctact ctgcttaaat
     4261 ctcctattgg cttgtgggcc ttggattata ttttggcttc ttggcactat caggtgtcgt
     4321 ttgaagcgct tgaaaaacgt gtgagccatt tttatcagac ctttcagatg tctccgatcc
     4381 ttgatcgtct gcaggcctgt ttgtacgctt tcatctttat tttatgtcgt taccaaagac
     4441 gagtggatag agtcaagcaa agaccggtag tggtttctga gcagctggat cagctaacag
     4501 ctcttttggt gtcagaaata atgcagcaat tgtctcttag gtatcagcta tttgaagctg
     4561 atgaggccta ttttcaattg ctgttagcgg gctgctttga gggtgagggg actgtcagtg
     4621 atgatttctt tgaatcacta accgctgcga ttgttgatca aatgcagggg gttgctttac
     4681 taagcttcag ccaatcagat cagctcaagg aggatttgaa gaggcatttg atcccagcct
     4741 attaccgttt gcgctatggt ttgccaagtg ataatgatta taccttgcgg gttaaggata
     4801 gttattctga gctctttgac ttggtaaagc agtctctgga gcctttagcc aaggagctgg
     4861 atagtcccat accagatagt gagattgctt attttgttct tcattttgga ggctatttaa
     4921 agcagcaggg aaaagatttt catcgtcaag cctatcgggc tgtgattgtc tgtcctaatg
     4981 gtgttagttc ttctttaatg atcaaggagc atttaaagct tttatttcct gatattgctt
     5041 ttcgggggct ttcaaggctt gatcagcttg ggcaattaga tgagagctgc tatgatttgg
     5101 ttttttcaac gatacgatta gagactgata agccctttta tttggtacct atgataatga
     5161 ctgatgagca ggcttttcag ctggttagct tggttaatcg tgattttcca gatattggct
     5221 atcggctaga ggttgaagag ctgctccatc ttatcagctc atatgcggtc attcatcaaa
     5281 aagaaaagct gcgctttgct ttgcagcaat atttaagaca agatgtgaaa agaaaggata
     5341 ttcgaccagt gttacaagac ttaattacca agaaaaccta tcaatcaacc tcagagcaat
     5401 tggggtggag agaggctatt tatttggcgg ctcagccctt gttagagagt gggcagattc
     5461 aagcgagcta cccggaggct atgattgcta aggttgagga gtttggtcct tttattaatc
     5521 taggtaaggg gattgctatc ccacatgcga ggccagagga tggtgtgaat caggtaggta
     5581 tgtcgatgct tgttttagag cacccgattt atttgttaga tgatcctaag caggagattc
     5641 gtttgttaat ttgtattgct gctattgata atgaaacaca tttaaaagcc ctgtctcggc
     5701 tgacgaccat tttaagagac aatgagcagg taaaggcttt acttgcatct acatcatttg
     5761 aggatattaa aactattatt gcagaggagg cataaaatgg cattaagaat tggtacagcc
     5821 tgtggttcag gcttagggtc tagctttatg gttcagatga atatcgaatc cgtattaaag
     5881 gacttgggag taaccggtgt tgaggtagag cattatgatc ttggcggcgc ggatcccaca
     5941 gcggcagatg tgtggattgt tgggcgtgat ttggcagact cggcagggca tctgggagat
     6001 gtgaggattt taaatagtat cattgatatg gacgaattga ctagtctggt aaaggctatt
     6061 tgccaagaag aggggcttat ctagaaggag cataagatga catttttact tgatattgtt
     6121 agcacaccag ctattttggt tgccttgatt gctattgttg gtctcttact tcaaaaaaag
     6181 ccagctcctg acattgttaa gggaggtatt aagacctttg ttgggttttt agtggtttca
     6241 ggtggtgcag gtattgtgca aggctcactc aatccttttg gaacgatgtt tgagcatgcc
     6301 tttcatctgt ctggtgttgt gccaaataat gaggctattg ttgcagttgc tttgacgacc
     6361 tatgggtcag cgacagctct cattatgttt acaggaatga tctttaatat tttgattgct
     6421 cgctttaccc gctttaagta tatcttcttg acggggcatc atacgcttta catggcctgt
     6481 atgattgctg tgattatgtc tgttgcaggc tttacgtcag tgtccttgat agtgtttggc
     6541 gggctggcct tagggattat catgagtgtt tcaccagctc ttgtgcaaag atacatgatt
     6601 cagctgacgg gaaatgacaa ggtcgctttg gggcatttta gctctcttgg ttattggtta
     6661 agcggttttg tgggaggtct tgttggagac aagaccaagt caacagagga catcaatttt
     6721 ccaaagagcc ttgccttttt gcgcgatagt acggtaagca ttaccctgtc aatggcaatc
     6781 atttatttga ttgtagctat ttttgcaggt cctgcttgga ttagcaagga attatcctct
     6841 ggcacacatg gcttggtttt tgccttgcag ttggcaggac agtttgctgc aggcgtcttt
     6901 gtgattttag ctggtgttcg tttgatccta ggtgaaattg taccagcctt caagggcatt
     6961 tctgaaaaat tagtgccaca ttctaagccg gccttggatt gcccgattgt ctatccttat
     7021 gcccccaatg cagtgctgat tggctttgtt tctagctttg ttggtggcct tgtgagcatg
     7081 gctgtgatga tcgtaagtgg aacgacagtg attttacctg gcgttgtgcc tcatttcttc
     7141 tgtggtgcca cagctggtgt tattgggaat gcttctggag gtgtgcgcgg tgcaactgtg
     7201 ggagcctttt tacagggtgt tcttattagc tatcttccga ttttcttgat gcctgtttta
     7261 ggcggcttgg gctttgaggg ctcaaccttc tcagatgccg attttggctt atcaggtatt
     7321 ttactaggaa cacttaacag cataggtggt gtgacagcta ttgtgattgg tatttttgtg
     7381 atattagctg gacttgttgg gctttctgtt gttggaaaat cagtagctaa ggaggaataa
     7441 gtatggcttt gagcgatgaa aagctaacgc aggtgaagcg attcgcagca gagattcgtc
     7501 taaatacctt ggagactctt aatcatctag gctttggtca ttatggcggt agcttgtcta
     7561 ttgtagaatt gctggctgtg ctttatggag aaatcatgcc tatgacacct gagctctttg
     7621 cccagtcaga tagagattac ttggtcttat caaagggaca tgcgggtcct gccctctata
     7681 gcactctcta tctcaaggga ttctttgata aggccttttt acagtctctt aataccaatg
     7741 gaacaagcct gccctcgcac ccagatcgtc tgttaacgcc tggtattgat atgacgacag
     7801 gctctcttgg tcagggaatt agcgtagcaa cgggcattgc ctatgctcaa gcgcttgagc
     7861 agtcaccaca ttatacctat actatcgttg gtgatggcga attaaacgag ggccaatgct
     7921 gggaggctat tcagcttgcg gcccatcagc agttaagtca tttctttgtc tttgttgatg
     7981 acaataagaa gcaattagat ggaacaaccg aggcaatctg tcgtccaggt gattttgttg
     8041 aaaagtttac ggcatttggc tttgaaagct tacgtgtaga tggtagggat gttcaggcta
     8101 tttttgaagc catcaggact ttgcaggcgt catcaagtca taagcccaag tgtatcgtcc
     8161 tagatactgt taaaggtcaa ggggtcagcg tactagagtc aatggcagct aaccaccatc
     8221 taagaccaac agcagccgaa aaggagatgc ttgctgccgc tgtcaggaag ctacgagcta
     8281 gtttggaggt gacaagatga ctcgagcaag tcaagaaatg cgtcatgttt accgagattt
     8341 cctcattgca gccaaccaag accaccctga gctagtagtt ctggaggcgg atttatcaag
     8401 ctcaatggca accaaccatt tggatcaggt gtttggtaag cgctatgtca atgtgggaat
     8461 tatggaggca gaaatggttg gtctggcagc aggtttagcc attaaaggct ataagcctta
     8521 cctgcacacc tttggtccct ttgcttcacg tcgtgtgttt gatcagctgt ttatctcatt
     8581 aggctatgcg cagctaagcg caacggttat tggctcagac gctggcgtta gtgcggaaat
     8641 gaatggcggt actcatatgc cctttgagga tctagggctg ctgcgcctga ttccaagggc
     8701 tattgtttat gaggtcagtg atgacgttca atttaaagct gttttaaagg aaaccctatc
     8761 actcgatggc ctaaaataca ttcgaaccat tcgtaaaaag ccagaggcta tttatcaagg
     8821 gcatgaggac ttttctaagg gctattgcct attgcggcag ggagaggatc tcgtctttgt
     8881 ctgctcagga atcatggtca agaggtgctt agaggtggct gatagaatgg cagagcaggg
     8941 ctattctatc ggtgtgattg atgttttcag agtgaagccg cttgctgatg agctaaaggg
     9001 tctacttaca ggcagtcctg ttctaaccgt tgaaaatcat aatcgtatcg gtgggcttgg
     9061 gagtgctatc tgtgagctac tggctcagga aagtaatact ccagtttacc gtatgggggt
     9121 ggacgaacgt ttcggtcagg tcggacagat ggattatctg ttagaggaat accagctgac
     9181 gccagcagct attgagcagc aggttttgaa gattttagcg gcagattagc taaaaaagcc
     9241 tatcaggtgt accacaccca aaaagctgga ccttatagat taggattgag ctttgtatga
     9301 aacagggttc agtcctttta gttatgcgct ttcagtccct ttcactctgt aggcgtgaaa
     9361 taatgattga taactcttga tttcaccttc taattttaat gtcatagaaa aagatcttaa
     9421 gcgttaggtt ttatcttcac ctttggggta caattctttt gtcaggactg atagggcctt
     9481 ttgctattac tgctgagttt ttggcatatt gtgagggctg ttttcatgaa gctggagaag
     9541 aatcgtttga tttcttagtg attgttcagt ttttatgatt aatcttactg ataaaaggac
     9601 caaagcagct aagcttttac tatctatgcc atgcgatacg aagaatgaac ttatttttga
     9661 acagaaagtt aatgtaaaac gagtattttg atcgattttt tggtagaatg taagagatta
     9721 cattattagg aatgaaatca atcctgacat aatggtttaa ctaaaaaaag gagctattca
     9781 tgacaacata tcaagaagat ttttatcaag ccgtcaatgg tcaatgggca gaaacagctg
     9841 ttatcccaga cgataagcct cgtacagggg gcttttcaga cctagcagat gagattgagg
     9901 acttaatgct gaccacaaca gatgcttggt tggctggtga gcatgttccc aatgacgcta
     9961 tattagaaaa ctttgtcaag tttcaccgct tggttgcaga ttatgacaag cgtgatcagg
    10021 tgggcgtagc gccagccttg gacttaattg aagaatacaa ggccttagga tcttttgccg
    10081 agtttgctag caaggtggct gattatgagc taaatggaaa accaaatcag tttccattta
    10141 gtgtagcacc agactttatg aatgctcagt taaatgtcct ttgggcagag gcaccaggtc
    10201 ttatcctgcc agataccact tactatgcca aagacaatga caaaggcaaa gagctgcttg
    10261 ctatctggcg tggcatgcaa gaggagctat tgcctaaatt tggcttttca catgaagagg
    10321 ctaaggactt gctggataag gttatcacgc ttgataaaca gctggcagat tatgtccttt
    10381 ctcgtgagga atattcagag tatgccaagc tttaccaccc ttatgactgg gccgagttta
    10441 ccaagctagt gccagaattg cctttagatg atatatttac tgtgatttta ggtgaagtac
    10501 cagacaaggt tgttgtgccg gaggagcggt tctggacaga atttgcagct gactattatt
    10561 ctgagaagaa ctgggagctg ctaaaagcct ggctagtgct tacagcagca ggtgcttatc
    10621 atacttattt gactgatgag attcgtgtgc tatcaggagt ttacagtcgt gccttgtcag
    10681 gaactccaca ggctatggac aagaaaaaag cagcctatta cttagcacaa ggaccattta
    10741 atcaagctct tgggctttgg tatgctggtg aaaaattttc accagaggct aaggctgatg
    10801 ttgaacacaa ggtagctaag atgattgagg tttataaatc tcgtcttgaa actgcggatt
    10861 ggcttgcacc agcaacacgt gagaaagcca ttacaaagct aaatgttatc accccacaca
    10921 ttggctatcc ggaaaaatta ccagaaacct atgctaaaaa ggtcatcgat gataagctat
    10981 cacttgttga aaatgctcag aatttagcca aaatttcaat tgctcattca tggagcaagt
    11041 ggaataagcc tgtggatcgt agtgaatggc acatgcctgc caacatggtt aatgcttatt
    11101 atgacccaca gcaaaaccaa attgtgttcc cagcagctat tttgcaggcg ccgttttatt
    11161 cgttgagtca aagctcatca gctaattatg gtggtatcgg tgctgttatt gctcatgaaa
    11221 tttcgcatgc ctttgatacc aacggtgctt cctttgatga gcatggtagc ctaaagaatt
    11281 ggtggacaga cgaggattat gccgccttca aggagcgtac cgataaaatt gtagagcaat
    11341 ttgatggtct tgattcttac ggtgctaagg tcaatggtaa attaacagtg tctgaaaatg
    11401 ttgctgacct aggtggtgtg gcttgtgcct tagaggcagc tcaatcagag ccagattttt
    11461 ctgccagaga tttctttatc aactttgcta ccatctggcg tatgaaggcg cgtgaggaat
    11521 tcatgcaaat gatggcaagc attgatgttc acgcacctgg tcaatggcgt actaatgtca
    11581 cactgacaaa ctttgatgaa ttccaccaag aatttgacat taaagagggc gatccaatgt
    11641 ggcgtgcccc agaggatcgt gtgattattt ggtaatcatt gctcattaaa aaagactaag
    11701 aggctttgta cggccctcct atcgttagaa cgtgcagtct agcttgtgga ggaaggcatg
    11761 cttctcttag tctttttgtg ttggataagc tcgaaaagct ctttttttag gtgtaaaaaa
    11821 aagattgaag atagctctta aaagctatcc tcaatcttat gatttatgat tagactagtt
    11881 gttaagcgca gctgccattg tagcagcaac ctctgattca aagtcgttag cttttttctc
    11941 aataccttca ccgacttcaa agcgagcaaa gctaatcgct ttagcattga ctgagtcaag
    12001 gtaagcttca accgttttgc tgtcgtccat gatgtaaact tgtgcaagaa gagtataggc
    12061 ttggtcaacc ttagtgttat caagcatgaa gcgatccatc ttacctggga taattttgtc
    12121 ccagatcttt tcaggcttac cttcagcagc aagctcagcc ttgatgtctt cttcagcttg
    12181 cgcaatcacg tcagctgata attgagcctt tgaaccatat ttcaagaatg gaagtgctgg
    12241 cttgttaacc attgcacgtg attcattgtc aagctcaata gcgtggttca attgtgccaa
    12301 ctcgtccttg ataaattgtg ggtcaagctc agtgtatgat aaaacagttg gcttcatagc
    12361 tgcgacgtgc attgatactt gcttggcaag tgcttcgtct ccgccttcaa caacagtgat
    12421 aacgccaata cggccgccat tatgttggta agcgccaaag tgttggtcat cagttttttc
    12481 aactagggca aagcgacgga atgagatttt ttcaccgatt gtagctgttg cattgacata
    12541 agcatcagca agtgtttcac cagaaggcat gataagagca agtgcttcgt cgttattagc
    12601 tggcttacct tctgcgatag cctttgcagt tgcgtttacc aattcaacga attgagcgtt
    12661 tttggcaacg aagtcagttt cagcattaac ctcaacaaca gcagcaacgt taccattaac
    12721 gtaaacacct gttaagccct cagcagcaac gcggtcagcc tttttagcgg cctttgccat
    12781 acccttttca cgaagaagct caatagcctt ttccatgtcg ccatctgttt caacaagtgc
    12841 ttttttagcg tccataacgc cggcaccaga tttttcacgc aattctttta caagcttagc
    12901 tgtaatttct gccattttta tttcctccaa aattagaatc ggtcctctta aagctcgctt
    12961 tagcagagcc cttgacctgc taggttttct tacttaaaaa ataacgagac agagcggaat
    13021 gctttgcccc gttagaccat gttgtgaata gcaaggagct atcctagttc aatatgcctg
    13081 acttagactt cgtttgaacc ttcaacaacc tcaacgattt cttcgattga ctctgcttga
    13141 gtatcagctt caaatgcaac ctctgcgtct tcaccttgac ggccttcgat aacagcatca
    13201 gccaatttag cagtgattaa tttgacagcg cggatagcgt cgtcgttagc tggaatgatc
    13261 acatcaatgt catctgggtc agcatttgta tcaaccattg ccacaactgg aataccaagc
    13321 ttcttagctt ctttaacagc gatttgttct ttgtgtgggt caacaacgta catcacatct
    13381 gggatacgag gcatatcctc aataccaccc aagaattttt caagacgagc acgttgcttg
    13441 ttaagaagtg caacctcttt cttaggaaga acctcaaagg ttccttcttc ttccatgcgt
    13501 ttgatttctt tcaaacgagc gatacgcttt tggatagttc cccagtttgt aagtgttcca
    13561 cccaaccaac gatggttaat gaagtattga cctgcacgag tagcttcgtc agcaactgct
    13621 tcagccgctt gctttttagt accaacaaac aaaataacgg catcattagc tgctgcatca
    13681 cgaacaaact cgtaagcttg atcagctaat tttacagttt gttgcaagtc gataacgtgg
    13741 ataccgttac gctctgtgaa gatgtattta gccatcttag ggttccagcg acgagtttgg
    13801 tgaccaaagt gaacaccagc ctcaagaagt tgtttcattg aaattactgc catgagtagt
    13861 ttctccttta tagaaatgtt tttttcctct cttagacgtc ggcttgcaac tccacctgat
    13921 ggcaacagaa tcacaatcga tctaagatga gtatttgttg tctgcacaac tacaacagta
    13981 taccaaaaaa agctagtcat agcaagccta aatacactaa aacccacgtc gtacgcatga
    14041 ggaaaatgca tgccattatt ttctaaccat atgcatgttt tcaatgcatt tttgatatgt
    14101 tgacgttttg acacgatcca tttttcaagc gcagcttagt tttactatca atctttctga
    14161 aaaagaacac atgaatcatg aaaagatatc agagaacata agtttcttca agcatttggc
    14221 gtaccccaaa tgcttgatct atcagccttg ctgtttatta ggcctctaaa aagcaaaaac
    14281 cagggtaaac agttaccttg gttttttgct aacttactga cgaatcaggt aatcaaatgc
    14341 tccaatagca gcagtagcac ctgaccccat agaaataata atttgtttgt aggctgaatc
    14401 tgtacagtcg cctgcggcaa agatacctgg aatattggtt gaaccatatt tatcaacaat
    14461 aatctcgcca cgatcggtta agctgatacc gctgtctttg agccaagctg tatttggcac
    14521 caagccaatc tgtacaaaga ctccttcaag gtcaagatgc ttttcttgat tgctgtcacg
    14581 ctcgatatag ttaagccctg tgacatgatc gtccccaaca atatcctttg tagcaacatt
    14641 ttttagaata gtcatattgt ctgttttagc agcgcgatcc tgtagcacct tgtcggcctt
    14701 aagctcaggt aagaactcaa gaacatagac atgcttagct aagccagcta aatcaagtgc
    14761 agcctcaagt ccagagttac caccaccgat aacagcaacg tttttatctt caaagagagg
    14821 accgtcacag tgtgggcagt aggttactcc tttattttta aactcatttt cgccaggaac
    14881 attgatactg cgccattttg caccaagcgc tagaatagct gttttagcct tcaagacagc
    14941 gccattagca agagtaacct caacaaggtc ttttttctca atcgaagtag ccagctgggc
    15001 tttgatgatg tcaacatcat aggatttagt atgctcctca acctgggcca taagctttgg
    15061 tccctctgta tacagggttc ctatcatgtt ttcgatacct acagtttcca tgacttgacc
    15121 accaaaggtc tcagccaaaa gacctgtatt taagccttta cgagcagcat agatggcagc
    15181 actatttcct gcaggtcctc caccaatgac aaggacgtca tagactcctt tatcagcaaa
    15241 ggcttcctta gatagaggtc ctgcgatttg ctcaagcagc tgttcaatag tggcgcgacc
    15301 agaagtgaat tcttctccat ttaaaaagac agttggtaca gacatgatgc cctttgcctt
    15361 gacttcctct tggaacatgc caccttcaac catggtatgt gaaatgttct tgttaagaac
    15421 agccataatg ttcaaggctt ggaccacatc tgggcaatta tgacacgtta agctgacata
    15481 ggtttcaaag cttaaaggac ggtcaatagc cctgatgcgg tcaataatat cctgctcaat
    15541 ctttggtgcg cgtcctgaaa cctgtaatag agcgaggata aaggaggcaa actcgtgtcc
    15601 tagaggcagt ccagcaaaga tcactccgct atcttgacct ttttgtgtaa tcttaaaact
    15661 tggttgacgt gttagggtag tctcctcaat agtgatgcgg tctgacatgg cagcaatttc
    15721 ttcaatgaag tccttgacct tttgtgagct atcgtcacta ccaagataag cttgtaggac
    15781 taagtcagat tccaaaagat taaggtattg agcaagctgc tctttaatat caggacttaa
    15841 tgccatagct tttctccttt gcctgcttaa attttgccga caaggtcaag gctaggtgtt
    15901 agtgtttcag ccccttcttt ccatttggct gggcatactt cacctgggtg cttacgaacg
    15961 tactgagcag cacgaatctt atcaatcaag ccgcttgcat cacgtccgat accatcagca
    16021 ttgatttcca tcatttggat aacaccatct ggatcaataa tgaaagtacc gcgttgagca
    16081 agtccgtcct caccaagaac atcaaaggct tgtgaaatag catgtgatgg gtcaccaatc
    16141 attgggtaag tgattgttcc aacaacatct gaatcatcgt gccatgcctt atgaacaaag
    16201 tgtgtatcag tagatacaga ataaacctca acacctaaag attttagtgt ttcatattgc
    16261 tcttgaaggt cacctagctc tgttgggcaa acaaaagaaa agtctgctgg gtagaagcaa
    16321 acaactgccc atttcccttt aagatcctca ttagttacag tgataaattt tccattgtga
    16381 aaagcttggg ctgaaaattc agcaatttcc tttcctacta aagacatgtc atgtcctcct
    16441 tttttacatt tgatacctgt attataagct aagaaatctt atctgtctac ttgtaaaccc
    16501 tagatttatc aaggtttttg atgttctttt ctaacaattt catatgtgaa tttagtcaca
    16561 ctgtttaaaa ctattctaaa taatagaaaa ctctgataat atcaaagatt ctcgaaaata
    16621 agtttttcaa ataattctaa tattattaaa aaacgatttt ctgatttaaa ctctaaaaaa
    16681 taacataaac tgaaaaagga gcagcctgct gaaaaatagc tgctattttt atcttgacga
    16741 atgctgtcaa ctagggtaaa atagttcttg ttatggcggt atagccaagt ggtaaggcac
    16801 ggctctgcaa aagcttgatc gtcggttcaa atccgtctac cgccttttat atacaaataa
    16861 aaaccttgat taacctcgcg aaaacgttgt taaatcaagg tttttatttt ttgcgacagg
    16921 ataaaaaaag agaaaaaaag aaataaagtc ggtcaaaaat cggtcaaatg tccgaagatg
    16981 tcttttatta cctgattgtt cttttctttg agtttatcta gctgatgggc atacactttt
    17041 aaagtgatgt ttaggttctc atgcccaagc aactgcgata tggatattag gtcaacgccc
    17101 tttaggatta aaaaagatgc gtaagtatga cgtagagagt gattacgcac aggacgacca
    17161 acaatttttt taactaatct attgcagagt gagttagaag ctccgtagag caccctattt
    17221 agcttatttt ctttataata attttcttta aatgctttga gcaattttat agtttgctga
    17281 tcaatgggaa tttgtctttt tgattgctcg ttttttgttt ccttaaattc ttgagttttt
    17341 gagtaatcaa atgatttatt aatgtctata aatccctttt caaagtctat gtcattccac
    17401 gttatccctg ttacctcagc aaatcgcaga ccagtgacag ctatgatgta tagagtaaag
    17461 taggaaatat actggtattt ctcactcgtt actttgacta gatttaagta ttcatcctct
    17521 tcaaggaaat caaattcttt tgctctagct tctttttgag attttacaat cgcaccttca
    17581 gcaaaatttg ttttgataag tccatctcta actgcgactt taacagcccc tttgatttga
    17641 tagtggaatt tttcaagcgt ttcttgggca tatttactag caaaaacatt cattttcttt
    17701 tggtaaagtg tatgtgttac tttattaagc ttgatatcgc caaaatattt tttgatgtgt
    17761 ttgaggtttt tagtgtaagt ctcccaagtt ttgtcgacga catgcggacg tttgtagatt
    17821 tcagcccatt ccttgcaaaa atcataaagc gttatatctt cgttattatt atctttgttt
    17881 agttcggctt cagctttgac tgcagccgca gtagctaacg cttttgtctt aaaaccacct
    17941 ttagattttt cccttttgct cccctgacta tctgtgtagt agatacggta agaccatttg
    18001 tctccacgtt ttctatattt tgccattgtt ttatacctca tttatgtgtt aaaataggca
    18061 tagtaaaaga cctgcttgag agctggttaa ttactatgat ggatgcacca tactcaaact
    18121 ttggtcgggg agagtgtggt gtttttatat aattgactaa tttaggaact ttatataaaa
    18181 tagttaatga agaaagtgct attttctatt ttcaattaga acctgccttc tcatttgcct
    18241 gaacgataga tttctacttc ctgttgtagt cctctatcgt ttttatttat cttatatcac
    18301 cgtttttcaa taaatcatat gctaataaaa ggcgtctctg agcagatagt tctgtagcag
    18361 agttgttata attatcagag aaaacaggca aaacagaact at
//
LOCUS       DARYSY010000043        17646 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYSY010000043 DARYSY010000000
VERSION     DARYSY010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17646
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(150..1820)
                     /locus_tag="TVR04_001422"
     CDS             complement(150..1820)
                     /locus_tag="TVR04_001422"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1270099.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDDDDLELYGNYKAKLSFEK
                     IKSVKGNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGIPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENVAAVRAGFANLKRHVENIRKFNIPVVVAINEFVTDTKAEIQAL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVSAIAEESAAYKRLYADKDSLEEKLRA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            2018..2710
                     /locus_tag="TVR04_001423"
     CDS             2018..2710
                     /locus_tag="TVR04_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1270100.1"
                     /translation="MAMKLLITSGGTTEAIDTVRGITNHSTGQLGKIIAETFLAKGFD
                     VTLVTTKTSVKPVKQPHLTIREVINVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMI
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKIISYIKEWNPNIRLVGFK
                     LLVNASDEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVDDKTVCSANTKEEL
                     AQLIYERIIAHD"
     gene            2703..3248
                     /gene="coaC"
                     /locus_tag="TVR04_001424"
     CDS             2703..3248
                     /gene="coaC"
                     /locus_tag="TVR04_001424"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1270101.1"
                     /translation="MTKQITLAVSGSISAYKAADLTSQLIKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPETTPKLIAPAMNTNMYLNPITQQNLKRLAALGFREIPPKTALLACGDT
                     GPGALADIDDIVTAISQQLAR"
     gene            3304..3876
                     /locus_tag="TVR04_001425"
     CDS             3304..3876
                     /locus_tag="TVR04_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1270102.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGVISVITNTLVLLPTSYLFSPFVTNGNLASLVIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFVFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
     gene            4055..5770
                     /locus_tag="TVR04_001426"
     CDS             4055..5770
                     /locus_tag="TVR04_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1270103.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDDKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINVFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLATHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGADG
                     GQMPPADADALTDYIRAIDNPFAIRLANLEEAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQNLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFESVQVVEAQAKPDPDFSTVKSP
                     NPESQEAFALAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
     gene            complement(6203..7159)
                     /locus_tag="TVR04_001427"
     CDS             complement(6203..7159)
                     /locus_tag="TVR04_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270104.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGAFSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPIIGDVLFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(7161..8225)
                     /locus_tag="TVR04_001428"
     CDS             complement(7161..8225)
                     /locus_tag="TVR04_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270105.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            complement(8218..9750)
                     /locus_tag="TVR04_001429"
     CDS             complement(8218..9750)
                     /locus_tag="TVR04_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270106.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKEVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            complement(9877..10929)
                     /locus_tag="TVR04_001430"
     CDS             complement(9877..10929)
                     /locus_tag="TVR04_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1270107.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            complement(11020..11409)
                     /locus_tag="TVR04_001431"
     CDS             complement(11020..11409)
                     /locus_tag="TVR04_001431"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1270108.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNVE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATSP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            complement(11396..12058)
                     /gene="deoC"
                     /locus_tag="TVR04_001432"
     CDS             complement(11396..12058)
                     /gene="deoC"
                     /locus_tag="TVR04_001432"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1270109.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            complement(12072..13349)
                     /locus_tag="TVR04_001433"
     CDS             complement(12072..13349)
                     /locus_tag="TVR04_001433"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1270110.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKVLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            complement(13448..14077)
                     /locus_tag="TVR04_001434"
     CDS             complement(13448..14077)
                     /locus_tag="TVR04_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1270111.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            14311..15231
                     /locus_tag="TVR04_001435"
     CDS             14311..15231
                     /locus_tag="TVR04_001435"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1270112.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQIYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVKLVTTDGFLYPNSTLIENNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYARYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            15285..15533
                     /locus_tag="TVR04_001436"
     CDS             15285..15533
                     /locus_tag="TVR04_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1270113.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     TEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLG"
     gene            complement(15744..16028)
                     /locus_tag="TVR04_001437"
     CDS             complement(15744..16028)
                     /locus_tag="TVR04_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270114.1"
                     /translation="MIAIEMILTGQEPIRALKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(16047..16439)
                     /locus_tag="TVR04_001438"
     CDS             complement(16047..16439)
                     /locus_tag="TVR04_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270115.1"
                     /translation="MTALEKIRAAIHQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQCRKMSQQE
                     EEIAHRYRSKRQAIEKDITALRRQWREG"
     gene            complement(16436..17638)
                     /locus_tag="TVR04_001439"
     CDS             complement(16436..17638)
                     /locus_tag="TVR04_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270116.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     AEDNPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLC
                     THEGPDSFKVVKSQLSTAKAFSDYIRTRYPNAAISYTGHSLGGYLALITAAHAKQPAT
                     VFNAPSSVNNLSKEAIDFVTANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKA
                     GIGRHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTDYRLLKKKYAASNGISS
                     SEEFYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEALHQKTRDMPFFVSELS
                     WAELEEAYAQAGVTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIATD
                     QKLGGDFS"
BASE COUNT         5171 a         4134 c         3277 g         5064 t
ORIGIN      
        1 tctatactgg taaaaaaaga ttgtgaataa cgattaaaat agtacaatat gagctattgt
       61 tatcagctta tccttagaca ttaaaaaaga ttgaagaaaa cccctttctg aagctttctt
      121 caatcctgat tctggctata acaaataaat caaaacaatc ctactgctgt accgtcttcg
      181 gtgacgtcca tcttcatagc tgcaggaatc tttggcaagc ctggcattgt catcacatct
      241 ccagttaagg caacgataaa accagcccca gtcttaggca ctaattcacg aatggtaatg
      301 tcaaactgat ctggcgcacc taggagagat ggatcgtctg aaaagctata ttgggttttg
      361 gccatgcaaa caggcaattg atcccagcca aattgggcaa attgcttgag ctgattttta
      421 gctttaggtc cgaattgcac agccctgcca ccatagattt cagtcacaat tgccctaagt
      481 ttctcctcta agctatcctt atctgcatat agacgcttat aggctgcgct ttcttctgca
      541 atagcactga caacagcatt ggcaagagca ataccgccat cagctccctt ggcccacaca
      601 cttgccaatt caaccggaac agctatttct gcacacaatt cttttagggc ttgaatttct
      661 gctttggtat ctgtcacaaa ttcgttgata gctacaacaa ccggaatatt gaatttacga
      721 atattctcaa catgacgctt taaattagca aagccagccc gaaccgcagc aacattttca
      781 aaggttaaat ccgctttagc aacaccgcca tgcatcttca aggcacgaag tgttgcgaca
      841 ataacaactg catcaggagc cttaggtaga ttcggtgttt tgatgttaag gaatttttct
      901 gctccaagat ctgctccaaa gcctgcctct gtaacagtat aatctgccaa ccgcagagct
      961 gttgatgtcg ccagaacaga attacagcca tgagcaatat tggcaaaggg tccaccatgc
     1021 acaaaggctg gtgtaccata gatcgtttga acaaggttag gcttaatagc gtccttcaaa
     1081 atcaaggcta atgccccttc tacctttaaa tcacgcacat atacaggtga tttatcatag
     1141 cggtaggcaa tcacaatatt agctaaacga gccttcaagt ccttgagatc agtcgccaag
     1201 caaaggatag ccatcacttc agaggctact gtaatatcaa aaccgtcttc tcttgggata
     1261 ccattgacag gactccccaa gccaacaatg acctgcctaa gagaacgatc attcaaatca
     1321 agcacacgct tccagatgat acgacgcggg tcaataccaa gctcattgcc ttgctgaagg
     1381 tgattatcaa taagggctga taaagcgtta tgagctgtgg taatggcatg catatctcca
     1441 gtgaaatgaa gattaatatc ttccatcgga agaacctgag cgtagccgcc acctgcagca
     1501 ccacccttga tccccataac tggtcctaga gagggctcac gcaaggccag catggttttt
     1561 ttaccgatct tagtcaaggc atctgccaaa ccgatagaca tggttgattt gccctcacct
     1621 gctggcgttg gatttatagc agtcactaaa atgagcttac caggcttatt gccctttact
     1681 gatttgattt tttcgaagga taatttggcc ttataattac cgtacagctc caaatcatca
     1741 tcatcaatcc ccaccttttt aacgatttct gtaatcggct ttaaggggac gctttgagca
     1801 atttcgatat ctgatttcat gaaaactcct tgactcttac ttgatagtat cattatatca
     1861 cactctatct taaacgtata tttatttatt ttcatttcaa aaacgttcgc ttttgaaatg
     1921 aaaataaaag aaaaaaagcc tagtagcatc agcatcgtca gtgaaaataa ttttaattag
     1981 tgattttatt tactattttt gctttttctg ataaaatatg gctatgaaat tattaatcac
     2041 gtcaggcgga acgaccgaag caatagacac tgttagaggg attaccaatc attccactgg
     2101 ccagctagga aagataatag ctgaaacctt tttagcaaag ggatttgacg ttactctagt
     2161 gacaacaaag acctcggtaa aaccagtaaa gcagcctcat ttaaccattc gtgaggtgat
     2221 caatgttgat cagctgatgg ctatcttaaa agaggaggtt cctaagcacg accttctcat
     2281 tcatagcatg gctgtttcag attatagccc agtgtacatg atagacttcg atacagtcgc
     2341 agctgctgat catttgcaaa cctttttaac agcaagcaat aaagaagcca aaatctcatc
     2401 ggcagctgat tatcaggtgc tctttctaaa aaaaacaccc aaaatcatat cctatattaa
     2461 ggaatggaac cctaatataa ggctagtcgg ctttaagcta ttggtcaacg cttcagatga
     2521 agagctgatt tcagtagcac gagatagcct gcataagaac aaagcagact atatagtagc
     2581 caatgaccta gcagatatca aggccaatca gcacaaggct tttcttgtcg atgacaaaac
     2641 agtctgctct gctaacacca aagaggagct tgctcaatta atctatgaaa ggataatagc
     2701 tcatgactaa gcagataaca cttgcagtct ctggtagtat ttctgcctat aaggcagctg
     2761 atctcaccag tcagttaatc aaaaaaggct atgaggttac tgtgctgatg acgcaagcgg
     2821 ctactgcttt catcactccg ttgaccctac aggtcttatc aaaaaatcct gtccatttag
     2881 acgtcatggc agagcatgat gtcaaaattg tcaatcatat cgagctagct aaagcaacag
     2941 atctatttgt ccttgctcct gcaagtgcca ataccattgc tcatttagcc tatggctttg
     3001 ctgataatat ggttaccagt gtcgccctag ccctacctga gacaacaccc aaactcatcg
     3061 ctcctgctat gaatactaac atgtacctta acccaattac tcagcaaaac ctcaaacgct
     3121 tagccgctct tggctttcga gaaataccac ctaagacagc cctgcttgcc tgcggcgaca
     3181 caggacctgg tgccttagca gatattgatg atatagtcac agcaattagt cagcagctag
     3241 caagatagct tgtcacagat tagcaattgc tgtattgtaa tataaaaatt aatggagaat
     3301 gcaatgaatc acaacaaatc ttctgaaatc tctcgtattg ccatcttttt tgcagttatg
     3361 ttggttattc actttattag cagctggttt ttttatatct ggcctgttcc gattaaacca
     3421 acgctcgtcc atattccagt tattgttgct tctatcatgt atggtccgcg cactggagct
     3481 attttaggag gcttgatggg ggttatcagt gtgataacaa acaccttggt gttacttcca
     3541 acaagctatc ttttctcacc atttgtcaca aacggtaatc tggcttcctt ggtgattgcc
     3601 atgctgcctc gtatcctgat tgggatcact ccttattatt gctataagct tatcaaaaac
     3661 gagcttgggc ttgtcctagc tggtcttgtt ggctcgctga caaacaccat ttttgttctc
     3721 tcaggaatat ttgtcttttt cccaacagcc tctggagaca atgttaaaac gtttctaact
     3781 accattgtat ctggcaacgc tattactgaa atgattgttt cagctatcgt taccattact
     3841 cttatcccag ctttatccaa gcttaaaaaa tcataatatg gctcacgcta tgaagcatgc
     3901 tgtctgttaa ggatagcatg cttttatgat atgtgacaag caagaaaatt gatccttatg
     3961 tgaaaaaatg attggaagct attacagaaa ataagtgatt tttccttttc aacatgatat
     4021 aatgaaagcg gttaaaaata taaaggagaa tactatgact tacacagaaa actatcaaaa
     4081 atggcttgat attccagatc ttccagccta tttaagagat gaattactta gcatggacga
     4141 caaaacaaag gaagatgcct tctacaccaa tcttgaattt ggaacagctg gtatgcgtgg
     4201 ctatattggc gctggaacga atcgtatcaa tgtttttgtt gttcgccaag caactgaagg
     4261 cttggcagca ttagttgagt caaagggaga agctgctaag aaggcaggtg tcgctattgc
     4321 ctatgattct cgtcattttt ctccagaatt tgcctttgaa tctgcacagg tgctagcaac
     4381 tcatggcatt aaatcatacg tttttgaaag ccttcggcca acacctgagc tttcctttgc
     4441 tgtgcgacac cttggtgctt ttgctggtat catggttacc gccagtcaca accctgctcc
     4501 attcaatggc tataaggttt atggggctga cggaggtcaa atgcctccag ctgacgctga
     4561 cgctctaaca gattacattc gtgcgattga taatcccttt gccattaggc ttgctaattt
     4621 agaggaagcc aaagctaatg ggctcattga ggtaattggt gaagctgttg accttgctta
     4681 tttagaagag gtcaaaaagg tcaatatcaa ccagaacctc atcaatgatt acggtcgtga
     4741 catgaaaatt gtctatactc ctcttcatgg aacaggtgaa atgctagcac gtcgtgcctt
     4801 agcacaagca ggctttgagt ccgttcaggt ggtcgaggcg caggcgaagc cagatccaga
     4861 tttttctact gtcaaatccc ctaatcctga aagtcaagag gcctttgccc ttgctgagga
     4921 gcttggacgt caggttgacg ctgatgttct tgttgctact gatccagatg ctgaccgtct
     4981 tggggttgaa attcggcagg cagatggcag ctatcgcaac ctatcaggca accaaattgg
     5041 tgctttaatt gctaagtata ttttagaagc acatcagcag gctggaaccc tacctaacaa
     5101 tgccgctctt gccaaatcca ttgtctctac tgagttagtg actaaaattg cagagagcta
     5161 cggggcaacc atgtttaatg tcttaacagg cttcaagttc attgctgaaa aaattcaaga
     5221 atttgaagaa aagcacaatt acacctatat gtttggcttt gaggagagct ttggttatct
     5281 cattaagcca tttgtacgtg ataaggacgc tattcaagcg gtgctattgg tggctgagat
     5341 tgctgcctac taccgctctc gtggactaac ccttgctgat ggtattgatg acatttacaa
     5401 ggaatacggc tactttgcag aaaaaaccat ttctgttacg ctgtccggtg ttgatggagc
     5461 agctgaaatc aaacagatta tggataaatt ccgcaagcat gcccctgcac agtttaatca
     5521 cactgatatt gtgttaacag aggatttcct cagtcagacg gcaactcata aagctggtca
     5581 aacccagcta accactcctc caagcaatgt cttaaaatat accctagctg atgattcttg
     5641 gtttgctgta agaccatcag gaacagagcc aaaaattaaa ttttatattg caactgttgg
     5701 tgataccctt gcgcttgccg aagaaaaaat tgccaatatt gaatctgaaa tcaacgcctt
     5761 tgtctcttaa atgagctgat atctaaccat gaccacccgt tataaggtgg tctatttgtt
     5821 tttacatcat tagctgtgag gcaaactgga gaagtggtct aagacctgtc gcttcctttt
     5881 tgggagcatg aattgaaacc tgctaaccac aagcaagctt gcacaggtcc tatcgctttc
     5941 ttttcagttg tgtggattaa aaaccacgca gcaaaaagca ccctaacctt gtcaaaacga
     6001 gccgatctct caattgtcag ttcagtgctt tagctagctt ttgtgaacac ttcacttgcc
     6061 aaaccaaagc taagctactt ctttgataaa aagcttgata gcatgccttt aaagagtctg
     6121 ttaaaagcaa aagagaagac gaatgtcgtc ttctctcgtg cttaactatc agtcacccac
     6181 tacagttgac attaagcttt ttttattttg atttgatgta attaacacca tctgcctttg
     6241 gagctactgc ttgtccaaag aaagcagcca aaatgataat ggttaatagg tatggcgcga
     6301 tttggaggta aaccgttggg attttttcca atactggtaa ttgtgcccca ataactgcca
     6361 agctttgcga taatccaaag aacaagctag atagcatagc acctaccgga ttccacttac
     6421 caaaaatcat agcggcaagg gcaataaatc caggtcctaa aatggttgtc actgcgaagt
     6481 taacagagat agattgtgcg tagacagccc caccaatacc cccaagaaaa ccagagatca
     6541 taactccata atatttcatg aggtaaacat taataccaag tgtatcggct gcttgagggt
     6601 gttcacctac agagcgcaag cgcaacccaa atcttgtttt gtaaagcaca aaccaagcta
     6661 ggaaagaaaa ggcaacagct aaatacccaa ctaagctagt atttctaaag agaacgtccc
     6721 caattatcgg aatttttgag agaatcggaa aatcaaactt accgaatgat tgctggatat
     6781 tatcagtttg ccccttaccg tacatcacct taaccaagaa aatggcaagc gatggtgcca
     6841 gcagatttag cactgtacca ctgacaatgt gatctgccct aaaattaatc gttgcaagcg
     6901 catggatcaa tgaaaagatc aatccaacaa ctcctcccac caaaactgca agccagggag
     6961 tagctttacc aaagatatga gcaaattcaa gattaaagac aatgcctgaa aaagccccca
     7021 tgaccataat gccttcaagg ccgacattga caacaccagc tcgttctgag aaggtaccac
     7081 caatacttgt aaaaataaga ggtgtagcat agataagcat tgatgaaacc aataaagcaa
     7141 aaatagtaac taaactcatc ttatttacct ccctttacta gttttttagg cctgataata
     7201 tagcgttcga taaggtagtg agcacctaca aagaagataa ttgaggcagt cactactttt
     7261 accaattctg gtggaattcc tgcgatattc ataccaggag cacctatgct caacacccca
     7321 aataggaatg atgagaagaa gataccaatc ggtgaattgg cagcaagcaa gctaacagcc
     7381 ataccgtcaa aaccaattgc tagagagctt ccctgtacaa aaacattctc aaaggttccc
     7441 aagccttcaa caactcctcc caagcctgct aaagcacctg aaatgatcat tgataggata
     7501 atcgtacgct ttgaggacat acctgcatat tctgaagcat gtggattaag acctactgaa
     7561 cgaatttcaa atccgagggt tgttttgttt agtaagaacc aaataactgc aattgcaata
     7621 agcgcaaaaa agataccgat attaatacga gaattattgg ttaaatctga cagccattga
     7681 ctttgatagc tggcattatc actgacctgt atggttgaat caatactttg cttaacactt
     7741 tcagggtagc ctctttgaat gatagcgtta ccgacataca gaataatata attcatcata
     7801 atggtaacaa taacttcact cgtaccaaga taagctcgca aaatacctgg aatagcgcca
     7861 gcaattccgc cggcaaccat accaatcaag acagtcatca gaattaaaag cggacgaggc
     7921 atattaggat tgacaagagc aaaccagccc gcagcaatcc aaccagccaa agcttgacct
     7981 gacagcccga cattaaagaa gccggcacgg ctagcaacgg taaaaccaag tgcaatcagg
     8041 attagtggtc ccatcgctct gaagatttca ccaatatttt tgatactacc aaaggctacc
     8101 tgaaataggc cctcatagcc ccaaattgga tcatagccaa agataaacat gacaatagcg
     8161 ccaagtaaga atcctaacaa gatagaaatc attggcacag caatcttttg tgcattttta
     8221 gacatgactc tcctccttat caatggaacc accagccatc aaaattccca attcttgctt
     8281 attggtatct tgaggcaaca caataccttg aattttaccg tcatgaataa ctgcaatacg
     8341 gtcagataaa ttcaagattt cgtcaagctc aaaactaaca acgagaattg ccttgccttt
     8401 gtcacgctct tcaatcaaac gcttatgaat gtactcaata gcaccaacgt ccaagccgcg
     8461 agttggctga ctgacaatca ataaatcagg gttacggtca acctcacgtg caatgatagc
     8521 cttttgttgg ttaccaccag aaaatccacg agctggaacc aattcattgg caccacgaac
     8581 gtcaaattcc ttcatcagtc tacgagcata atcgttgatt gtattgtaat ttaaaatacc
     8641 gttcttactt agtggctctt tataataggt ctgaagcgca gtattttcag ccaaggaaag
     8701 gtccaatacc agtccatctc tatgacggtc ctcaggcaca tgccccactg atagctctgt
     8761 gattttacgg gagcttaaat gaacaacctc ctgacctttg attgtaatgc taccagatct
     8821 agtctttctc aagcctgtaa tggcctgaat cagctctgac tgaccattac catcaatccc
     8881 tgcaatcccc acaatttcac cagctctaac gtcaagagaa agccccttta ctgctggaat
     8941 accacgattt tcatcgacct ctaaattctt gatggacagc accacctctt taggctctgc
     9001 tgccttttta gctgttgtaa aggaaaccga acgaccaacc atcatttcag ccaagtcctg
     9061 agaggttgca cctgctacat ctactgtttg aatgcttttt ccacgtcgaa taacagtgac
     9121 tctatcagca actgctctaa tttcgtccag cttatgagta atcaaaataa tcgatttgcc
     9181 ttcctttaca agattacgca taatttccat tagctcttgt atttcagcag gcgtaagcac
     9241 cgctgttggc tcatcaaaaa taagaatatc tgcaccacga tataaggtct ttaagatttc
     9301 aacacgctgc tgtgccccta cagaaatatc agcaatcttg gcagtaggat caacagctaa
     9361 accatatttc tcagaaagct ctttaatgtc cttgctagcc ttttttaaat caagacaacc
     9421 gtttttgaca acttcatttc ctaaaatgat attctcagca actgtaaaag cttctactag
     9481 cataaagtgc tggtgtacca ttccaatacc caatctagca gatttggaag gagagtcaat
     9541 aacaacaggc tgaccgttaa tgacaatgtt tccactagtt ggctctaaaa gcccagctaa
     9601 catattcatt aacgttgatt tacctgcacc attctctcct aacaatgcat gaatttcgcc
     9661 ttttctgaca ttcaaattaa tatggtcatt cgcaacaaaa tcaccaaatt tttttgtaat
     9721 ctctttcatt tcaatgacat gctgtgccat aggattattt cctttcaatt taatcttttg
     9781 tttcagtaaa gccagccatt tgtcacaacc tttactgaag caaaaggtgt tccactctaa
     9841 aaagggcgac cgacgaaggt cgctcttttc cagtaactac ttttcaggaa cttttacgtc
     9901 accagattta attttttctt tcgcttcttc gatggctttg ataacgtctt tagaaagatt
     9961 tgttgtggca atctcaacac caccgtcctt cagaccataa acagttgttt tacctgcagg
    10021 gaatttctta tctgctgcct gcttattgat caattgaaca gccttaccaa caccttttat
    10081 agtagatgca agtacaaagt tagatgattt gccatcctta gatgtatatt taccttcttc
    10141 gttttggtcg cggtcaacac caattaccca aaccttatca gcttcgtcac gtttttcgtt
    10201 aattgttctt gcttcgttga aaacacccgc acctgttcca ccagctacct gatagataac
    10261 atcagcacct gctgcgtatt gcgctgctgc aattgtctta cccttagcgg catctccaaa
    10321 tgatccagcg tagtccacct tgatcttgat tgagtcatca acagacttaa cgcctgcctc
    10381 aaagcctttt tcaaagcgtg taacaactgt tccttccata ccacctacaa aaccaactgt
    10441 ttttgttttt gtagtcatag ctgccgcaat acctgcaagg taagcagctt cgttatcagc
    10501 aaatgttacg ctagcaacat tgtctttgcc ttcgataaca tcatcaatga taacaaattg
    10561 tactttgttg ttgtcatcag cagccttact gattgcatcc ttcaaggcaa atccgatacc
    10621 ataaacaacc tcataaccac tagaaactgc tgtatcaatg ttagttgcat attcagactc
    10681 gtttgtagat tggaagtaat caaagcctga accctttgtt agtccattgt ccttacccca
    10741 agcctgcaag ccttcccaag ctgattggtt aaatgactta tcatcaacac caccagtgtc
    10801 agtaaccatt gctaccttca aatctgtttt agcatcacca gatccctttg aagcgttacg
    10861 attaccacaa ccaactaaac ctaataaagc tacagaagct aaaccaacac caataaattt
    10921 cttgttcatg aatatgaacc ctcctaaaaa tatttctagc aaaccaattg ccgaaagtaa
    10981 atataaagcc taatggctag ataacaaaat taagtcagat tacgataaat ctgtaaacga
    11041 ataaggaagt aactcgccaa cagttgtgcg catggtacga ccgtccttag caattagcgt
    11101 tactggagaa gtggcttcaa aaaattctgc catgacctga cgacaggcac cacaaggaga
    11161 gattggctca tcagtctccc cataaatggc aatttctaaa agctgctgat gtccctcaga
    11221 aacagccttg aaaatagctg tccgttctcc acaattggtc aagccaaagc tggcattctc
    11281 gacattacaa ccggtataaa tcgtcccatc cttggtcttt aaagcagctc cgatcggaaa
    11341 gtgtgagtaa ggaacataag ctcttttact agcttcaatt gccaacgaaa ctaaatcagt
    11401 agcctccatt ggcaacttca cctttcataa tcgttacccc tgcagaagtt ccaatacgtg
    11461 tagctcctgc ttcaacaaaa gctaaagcgt cctctagaga acgagcacca ccggctgcct
    11521 tgaccccaat atctggacca actgtctgac gcatcaattt aacatcagaa acggtcgcac
    11581 cgccagttga aaaaccagta gaggtcttca caaagtcaac acctgcattt accgccaact
    11641 gacaagcctt aaccttttca tcatcagtca agaggcaagc ctcgataatc accttgacta
    11701 atttgtctcc gctagcctct accactgcac gcatatcatc ttcaacagct tggtagtcac
    11761 cctgctttaa cagaccaata ttgataacca tatcaatctc atcagcacca ttttcaatag
    11821 cgtcctttgt ttcaaaggcc tttgttgctg aggtagttgc acctaaagga aaaccaacaa
    11881 ctgtacaaac cttaacgtct gtccccttta aagcctttgc agcataggct acccagcaag
    11941 ggttgacgca aacgctagca aagtcatagg ctttagcctc ctcaattaat tggtcaagct
    12001 gcgattgaac gctgtcagct tttagtagtg tgtggtcaat atacttgtta atattcatgt
    12061 tatactcctc cttaggaaat gattttgata atttcgttag cctctaggtg ttccgcccct
    12121 attttaacat ttttttcaaa ttctgtaagc actttttcgt ctagggcttc ctgtgaaaag
    12181 acaactgcaa tgcgctctcc cttagcgaca gcgtcaccaa ccttcttgtc aaagacaatc
    12241 cctgtttcat aatccagact atctgttttg actgctctac cagcacccag cctcattgca
    12301 aacaatccaa actcaagagc aggcaatgct gtgatgtaac catcttctga cgcaaaaacc
    12361 tctgtttgaa cagccgcctg tgatggacga taaaggtcct caagatcacc tccttgataa
    12421 acaaccatct cttctaattt tttcaaggct gctccgccaa ccaaatgatg gtgaatatcc
    12481 tcaagagagt gttgagcacc agcaagctcc agcataatct gagctagctc acaaataaag
    12541 tgagtaatat ccttgcgtcc cttgcctttc atgatatcaa ttgcctctag cacctctaag
    12601 cgattaccga tagcacgacc aagaggctga ctcatatctg taatgacagc cactgtctga
    12661 cgcccaacct ccttaccaag gtcaaccatc agtctagaca gcttctcagc atcttcaata
    12721 gtcttcataa aggcaccgtc accaacggta acatctagca aaatactatc agcgccagca
    12781 gcaattttct tactcataac agagcttgca atcaaaggaa caatatcaac ggttgccgtc
    12841 acatcacgaa gagcataaag cagcttatct gccttcacaa gcttatctga ttgtccaata
    12901 actgaaagtc cgatctcttg tacctgcttg ataaattcct cttgggtccg accaatctga
    12961 aagcccttga tagattctag cttatcaagc gttccaccgg tgtggcctaa gccgcgtcca
    13021 ctcattttcg ctacaggaac gccaaagcta gcaactagag gagctaagat gagtgtcacc
    13081 ttatcaccaa caccacctgt tgagtgcttg tccgtcttga taccagctat agctgacaaa
    13141 tcaatctgct cacctgtctc aaccatgctc atggtcaaat cgcgagtttc tcgtgtagac
    13201 attcccttga aatagatcgc cattgcaaaa gccgacattt gataatctgg cacagtacca
    13261 ttggcataac cattaatcag ccactggatc tcttcggtag atagctcttt accatcacgc
    13321 tttttttgga ttaaatcaac tgctctcatc aacaagatac caaaagctct gagaaaatag
    13381 tgatattaga aggcaactct tactaaaata ctgctatgct ttttaatacc actttttaca
    13441 cttgagctca attcctttcc ttaatacttc ttaaaatgta gtaacccttt tctcttttga
    13501 gaatagtcac attcccaaaa acggcctcca ttttgtcttt agcacttggt gctccctgct
    13561 tcttttggat aacgactgtc aaatcaccgc ctttagttaa aaaatcaata ctcttttcaa
    13621 taatctcatg aaccactttt ttccctgccc taataggtgg gttactaatg atgtgctcaa
    13681 atgtccctgt cacaccgtca tagaggtttg attgaaaaat ggtcgcctca acctgattac
    13741 tctcagcatt ctgcttagct aagccaacag cgcgatgatt aatatctact agagtcgcct
    13801 caacaccttg agcctttgcc aagctaagtc ctagcggccc atagccgcag cccaagtcaa
    13861 gcagacgatc accttcttga aaatctaatg tgttgagcag gacctgactt ccaaaatcaa
    13921 ccattctttt tgagaaaaca ccagaatctg tcaaaaaagt aaaggactgt cctaacaaat
    13981 tgaccgtcaa ttgatggata tcatgagcac tatctggatt ttcatcataa tacatttttg
    14041 tcatgtgttt tcctatcttt tttcgatgct ttttcattct atcacacttt gaaatggttt
    14101 acaagacgtt tgtttttctt ggtttttcgt ttatcgaacc atatattccg aacattgacc
    14161 gattaacttt atattagcca attgttaggc taaaattgtt cgatttttat agggtttttc
    14221 agtgtttttt taagaatttc agacgaaaca tttttcaatt tttttattga catgttataa
    14281 tgtaagcact gccaattagt aggagtaact atgtcaaacg aatttattac ttttgaaaaa
    14341 atttccagaa aatcctggaa gcaattacat caaaaaagca agcccttatt gactcaagag
    14401 gagcttacta gcatcaccag tttgaatgat aatattgata tcaacgacgt tgttgaggtt
    14461 taccttcctt tgattcatct cattcaaatc tataaaatcg ctcaagaaaa cctgtctttt
    14521 tctaaaagcc tctttctaaa aaaagatatt cagcaaagac cctttattat tgggatttct
    14581 ggctcagttg ccgtcggtaa gtccacaact agcaggttat tgcagcttct tttggcgcgc
    14641 acacacaaga ccagcactgt taagttggtc acaacagatg gttttttgta ccctaatagc
    14701 acactaatcg aaaacaatat gctgaatcga aagggcttcc cagaatccta taatatggag
    14761 ctattgttaa actttctgga tactgtcaag ggaggacaaa ccgcatcagc ccctgtttac
    14821 tcgcatgaga tttatgatat cgttcctgat cagcagcaaa cctttaccaa tcctgacttc
    14881 ctcatcatcg aagggattaa tgtttttcaa aatcaacaga ataatcgatt gtatatgagt
    14941 gattattttg atttttcaat ttatattgac gcagatagcc atcatattga gcaatggtat
    15001 ttggaacggt tcttaagcct tttagagctg gctaagcatg atccggctaa ctattacgct
    15061 aggtacacct cattgccaca aaatgaagcc attgcctttg caaaaaaggt ttggaaaaca
    15121 attaacctag aaaatctgga aaagtttatt gagcctacac gcaaccgggc agagctcatt
    15181 cttcataaag cggcagacca taaaattgac gaaatttatc tcaaaaagtg ataagtgctt
    15241 gccaaacacc tataatttct atataatggt gtagttagat taatttggag gtgaaaacat
    15301 tggcaaatat taaatcagct attaaacgcg ctgagcttaa cgttaaagca aacgaaaaaa
    15361 attcagcaca aaaatcagct atgcgtactg ctatcaaggc atttgaagca aacccaactg
    15421 aagagctttt ccgcgctgct tcttcaagca ttgataaagc ccaatcaaaa ggtttgattc
    15481 ataaaaataa agcaagccgc gataaagcac gtcttgctgc aaagcttggc taatacataa
    15541 ccaatgaaaa ctccaatcgg agtttttttc tttttggctt tagaaaaccg ttagcacagc
    15601 tggtgcttcc aaatgggtga tggtgattca tcagccctct agggcagcgc ctttgcttct
    15661 tactgctgct cacatcgcaa gtctagcagt gtggtgactg ctgtaaaagc ctagacagct
    15721 ggtaggacat gaagaactta ctattacatc aggctgctat agcccctgtt ctgtgtctta
    15781 atcgcctgct cgagcgctgt cctgccttgc cctctaatgc tgctatctag ctgattgaca
    15841 atggtctgaa tatgatctgc ggtgtctgtg gcaatccgag atacctcact gtcatagcgc
    15901 ctttgaagag catgaagcct gcctaaggtc aagggggcac atatggactg aaccaatctc
    15961 ctatctagct ctttctttaa agccctaatc ggctcttgtc cggttaaaat catctctata
    16021 gcaatcatct tcttatctcc ttttccttaa ccttcacgcc actgacgcct cagcgctgtg
    16081 atgtccttct ctatagcctg tcgcttgctg cgatagcgat gggctatctc ttcctcctgc
    16141 tgcgacatct tgcgacattg ttcgtgatag cactgctctg ttcggtgctg gtagtcatca
    16201 ataagtctcg ttagaacagt atattggtct gttatcagac tagcatcata atgtctgagg
    16261 tagctgctaa cggcctgata gctagaggca tagagctctt gcagctggtt atagttgcct
    16321 cttaactcgt catgggctgc tgccatttgg agccgctctt gatgatagtg ctcctgcagc
    16381 tcctctagct cctcttcctt ttgatggata gcagctctga tcttctctaa tgctgtcatg
    16441 aaaagtcgcc tcctagcttt tggtcagtag cgattgtcct ttcgatcccc tcctctagct
    16501 gctcctttac ggtcttgaac ttagtggcca gtcccctggc ctgagcgacc ttgtcatcaa
    16561 agtgcctcct ggtctgaccg acaaggctgt cataggtcac tcctgcctgg gcataagcct
    16621 cctctagctc cgcccagctc aattcactca caaaaaaggg catgtctctt gtcttttggt
    16681 gaagcgcctc tgcctctgca accgcctcct tccgacgagc gatgatctcc tcttgggcaa
    16741 gctgagtggt ctgctccaaa gcctgtgcga ctgctcgagc ctgaaactga tcaaggtaaa
    16801 actcctctga gctgctaata ccgttagagg ctgcatactt tttctttagc aggcggtagt
    16861 cggttagctt tgagcttagg gtagcaagag caggtgcttg agcagcggca ggacgaccct
    16921 tacggtcaat cacctgaccc tttgagttga agcgataagc ggctaagcta tgacgtccta
    16981 ttcccgcctt accgtcaacc catcttgaaa tccctagctc atcatctcca aagtaagtgc
    17041 ctaggtttcc aatgtagtca ttgttaatac ggtagctgtg atagagtccc ttgttggctg
    17101 taacaaagtc aatagcctcc ttggagaggt tattaacaga gcttggcgca ttaaagacag
    17161 tggcaggctg cttggcatgg gctgctgtga tgagtgccag atagcctccc agagaatgtc
    17221 cggtgtagga gatggcagcg ttaggatacc ttgtcctaat gtagtcggaa aaggctttag
    17281 cagtgcttag ctgactcttg accactttaa aagaatcagg cccctcatgg gtacacaggt
    17341 attgatcatc tccaaaaaca acggattgaa tatcggtgtc aatatcgcgt atatcactgc
    17401 tatttgtccc ggcataggca atgacgatat gacttctatc ctctttgcca tcttttattg
    17461 gcacaacagc catagcttgc ataccattgt cgggattgtc ttcagctttg aggacgcggt
    17521 aatctttccc gttagtttta aaagtcttac cgtttcgcca aggtctaata actttgccag
    17581 catcaacttt ataaacccca tcggctatat cattataatt tttatctgtt actatcattg
    17641 ttactc
//
LOCUS       DARYSY010000044        17588 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYSY010000044 DARYSY010000000
VERSION     DARYSY010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17588
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            676..2508
                     /gene="lepA"
                     /locus_tag="TVR04_001440"
     CDS             676..2508
                     /gene="lepA"
                     /locus_tag="TVR04_001440"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1270117.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEAILEQIVEKVPAPSGDVDKPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHREFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            3033..3470
                     /gene="msrB"
                     /locus_tag="TVR04_001441"
     CDS             3033..3470
                     /gene="msrB"
                     /locus_tag="TVR04_001441"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1270118.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSRPIHHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPREAGGLRYCINSAALKFIPYDQMEQEGYAKWLGIFDKS"
     gene            3758..4777
                     /locus_tag="TVR04_001442"
     CDS             3758..4777
                     /locus_tag="TVR04_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1270119.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALIYQNRAYTKAGIAFTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            5121..5546
                     /locus_tag="TVR04_001443"
     CDS             5121..5546
                     /locus_tag="TVR04_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1270120.1"
                     /translation="MKRKFLIGSHGKMASGLKSSIDILAGRGQELQIIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMNSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            5561..6052
                     /locus_tag="TVR04_001444"
     CDS             5561..6052
                     /locus_tag="TVR04_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1270121.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNNKVSLSQ
                     LIK"
     gene            6070..6879
                     /locus_tag="TVR04_001445"
     CDS             6070..6879
                     /locus_tag="TVR04_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1270122.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            6876..7703
                     /locus_tag="TVR04_001446"
     CDS             6876..7703
                     /locus_tag="TVR04_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1270123.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            7874..9508
                     /locus_tag="TVR04_001447"
     CDS             7874..9508
                     /locus_tag="TVR04_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1270124.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLVFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKAFLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSLLRISMDNEEGHHLLLI
                     KPIKVEHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQLDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMVLDMQAISRQEKSAIDLQSQDEFQYLSVQINQMINRL
                     QALHQKTLALEKQNVIFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIVVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFTKVELIFCQRDERFLLTYVVKE"
     gene            9512..10297
                     /locus_tag="TVR04_001448"
     CDS             9512..10297
                     /locus_tag="TVR04_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270125.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGARLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQGSDRSSL"
     gene            10321..11331
                     /locus_tag="TVR04_001449"
     CDS             10321..11331
                     /locus_tag="TVR04_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1270126.1"
                     /translation="MVIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIVTLKEDYDYITGHKKDILERYNQLRKT
                     TD"
     gene            11584..13368
                     /gene="uvrC"
                     /locus_tag="TVR04_001450"
     CDS             11584..13368
                     /gene="uvrC"
                     /locus_tag="TVR04_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1270127.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEIFIPEMIDETLVAAIVPARIVKPQRGEKR
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQVPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALIDHLTSKSDT"
     gene            13496..14098
                     /locus_tag="TVR04_001451"
     CDS             13496..14098
                     /locus_tag="TVR04_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1270128.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            14179..15588
                     /gene="pepV"
                     /locus_tag="TVR04_001452"
     CDS             14179..15588
                     /gene="pepV"
                     /locus_tag="TVR04_001452"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1270129.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFAAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(15855..17231)
                     /gene="mnmE"
                     /locus_tag="TVR04_001453"
     CDS             complement(15855..17231)
                     /gene="mnmE"
                     /locus_tag="TVR04_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1270130.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKN
                     LTTVASHTLNYGHIIRPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLITNTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTQEFQALLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQLFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         4915 a         3336 c         4097 g         5240 t
ORIGIN      
        1 cagtctttta gagcgaagag cgacttgaag aaactgataa atgtgtttgg ttttctgcta
       61 aaaatcctgc caaaaaatct ttggcaggat ttttatttta ctaagagata tttaggagtg
      121 gctttgtcat ttaatgcaga ttatgatata gcgggagaca tattgttgaa gctgtctatg
      181 tcacttttgg tggcaggtag gtcttattgg aattggtgac ttatgacatt tatcggtggc
      241 tgtaagcgtt tgactttttc acgtttcata gtggtccgct ctggaatgag tgggtatttt
      301 ttcagaatat gatcaaagat agatgacatg ttttacagca ggctatagct ggtatgattt
      361 gtttaaaaaa tcaaggccaa tgataagggc tgggtgacat aagtcttatg gctttacttc
      421 ttgttagctt gtgtcagcag gtgctgagtc aatcgttgta ggaattatcg taaacctaac
      481 agtagctgct gttctatttg tttattttct ggtttatatt caagttccta aaatgctagg
      541 gcaacaaata aatgatttat tgaaacaagc aagtggcggt actgcgatta ttgcctgctt
      601 aaaaggttgc tgtagcgcca ttgtcattat tttggtacaa tagtaggtaa aagactaaat
      661 gtataggaaa atagaatgaa cagtcaagaa ttaaaaaaac gtcaggagaa cattcgcaat
      721 ttctctatta ttgcccatat tgatcatggt aagtctactc ttgccgatcg gattttggaa
      781 aaaacagaaa cggtttcaag tcgcgaaatg caggcccagc tccttgattc tatggacttg
      841 gagcgtgagc gtgggattac catcaagctg aatgctattg agttgaatta taaggctaag
      901 aatggtcaag attatatttt tcacttgatt gatacgccag ggcatgtgga ctttacctat
      961 gaggtgtctc ggtcactggc tgcctgtgag ggtgctgttt tagtggtgga cgctgctcag
     1021 gggattgagg cacagacctt agcaaatgtg tatttggcgc ttgataatga tctggaaatt
     1081 cttccagtga tcaacaagat tgatttacca gcagctgatc ctgaaagggt ccgtcaggaa
     1141 atagaggacg ttatcggttt agatgcttca gaggctgtgc ttgcctctgc aaagtctgga
     1201 attggtattg aagctatttt ggagcaaatt gttgaaaagg ttccagcacc gtctggtgat
     1261 gttgacaagc cgctgcaggc cttgattttt gattcggttt atgatgctta tcgcggggtt
     1321 atcctgcagg tacgtgttgt caatggtatg gtcaagccgg gtgatacgat ccaaatgatg
     1381 tcaaacggaa aaacctttga tgtgaccgaa gtggggattt tcacccctaa ggctatcggc
     1441 agagactttc ttgctactgg tgatgttggc tatattgcgg cttcaatcaa gacagttgct
     1501 gatacgcgtg tcggtgatac ggtcactctg gctacaaatc ctgcagcaga gcccctgcat
     1561 ggctacaagc agatgaatcc aatggtgttt gcagggattt acccgattga gtctaacaaa
     1621 tacaatgatc ttcgtgaggc cttagaaaag cttcagctta acgacgctag tctacagttt
     1681 gagcctgaaa cctcgcaagc actaggcttt ggctttcgtt gtggctttct tggactattg
     1741 cacatggacg tcattcaaga gcgcttggaa cgtgaattta acattgattt gatcatgacg
     1801 gcaccgtctg ttgtctatca tgttaataca actgatggtg acatgcttga ggtctctaac
     1861 ccgtcagaat ttccggatcc aactaaggta gatagtattg aggagcctta tgtcaaggcc
     1921 cagatcatgg taccgcagga gtttgttggt gctgttatgg agttggccca gcgtaagcgt
     1981 ggggattttg taacgatgga ttatattgat gacaatcgtg tcaatgtgat ttaccatatt
     2041 cccttagctg aaattgtatt tgacttcttt gataagctga aatcatcaac gcggggctat
     2101 gctagttttg actatgaaat tgctgaatac cgtcgctcgc agctggtgaa aatggatatt
     2161 ttgttgaatg gcgataaggt tgatgccctt agctttattg ttcatagaga gtttgcctat
     2221 gagcgtggca agctgattgt tgaaaaattg aagaaaatca ttcctcgtca gcaatttgag
     2281 gtgccgattc aagcggctat tggtcaaaag attgtggctc gctctgacat caaggcttta
     2341 cgtaaaaatg ttcttgcaaa atgttatggt ggagatgttt cacgtaagcg caaattgctc
     2401 gaaaagcaaa aggctggtaa gaagcgcatg aaggcgattg gctctgttga ggtgccgcaa
     2461 gaggccttct taagtgtctt gtcaatggac gatgagagta agaaatagtg atatgctaag
     2521 taaggagcta gatcatgcga tctggctctt atgatttatg acttgatagg ctagaaaata
     2581 ggacttgtgt catggtaggc ttgtatgttt gagatggttt ggagcataat ggccctatca
     2641 tatctgtagt ggattgacaa agagctgtaa atattggtat ttggatagtt cattccgagc
     2701 cattctgtgc tactcttaag gtctttcata tgagcttttt taatgatggt ttgggataag
     2761 tcatatgggg tttttggata cattgaaaaa gcctccaatc tccacagtgg cgttccctct
     2821 acagagatga tagagccaga gtaatcgtta tgatctggag ctttgacgcc aagccttaat
     2881 gcaggagggc ttaatcagac tgctgttagg cttgaaggct taagccatac tggctgtcag
     2941 ctttatttag aggagcataa gcttatggct cacaaatgct cggtcttttt gttacaatag
     3001 agttaatcag ttatttttat aaggaggcag ctatggaatc taaggaagag cttcgccagc
     3061 gtattggaga tttggctttt gaggtcactc agcatgcagc gaccgaaaga gcctttacag
     3121 gtcagtatga tgattttttt gagaagggga tttatgttga tgtggtgagt ggagaggtgc
     3181 tcttttcctc tttggataaa ttcaattctg gctgcggttg gcctgccttt tcaaggccaa
     3241 ttcaccaccg tatggtaacc aatcatcatg actcatcaca tggtatgcga cgtgttgagg
     3301 tcaaaagtcg tgaggctggt tcccatctgg ggcatgtgtt caatgatggt cccagggagg
     3361 cagggggctt acgctattgc attaactcag ctgcgctgaa atttatcccc tatgatcaaa
     3421 tggagcaaga gggctacgcc aaatggttag ggatttttga taagagctag gaattgctag
     3481 cggccaatga aaaggtagag ctcttagcca atgctagtgg ctaaatcaaa gaaataaaaa
     3541 ggtggctaaa gtacatagag aaaagaggta agcagattgg caggtggtca atctgctttt
     3601 tgtgaggaga ctttcagcct gctttgcgct aaaaagtatg acaccaataa accacctact
     3661 atgcgggtgt gtgtcggtgg ttagcttaag ttttttcagt tcggttttac aagcttctct
     3721 aaaaggacta taatagctaa tggaaaagga gattcatatg ctaacgtctt tagaaaaatt
     3781 accgggcgtt ttactgtgct tgctgttagc actgcctgcc tggtatttgg gaagcttatt
     3841 tcctattatt ggagcgccag tttttgctat tttattggga atgctattgg ctcttattta
     3901 tcagaatcgt gcctatacta aggcaggaat tgcttttacg tccaaatata ttttgcagct
     3961 ggctgtggtt ttcttgggct ttggcttaaa cgtgacacag gttttagtgg ttggcttgca
     4021 atccctgccg attattgtag taacgattgt gactgccttg ggcataagct atttgttcaa
     4081 aagatggtta aggctaccag ccaagacagc tatcttagtt ggtgtgggct cgtctatttg
     4141 tggtggctct gctattgcag ccacagctcc tgtcattgat gcgcaggacg atgacattgc
     4201 caaggccatt tcggttattt ttttgtttaa tatcttggcg gccttgctgt ttccagcttt
     4261 gggtcagatg cttggcttat caaatcatgg ctttgctatt tttgctggaa cagcagtcaa
     4321 tgatacctca tctgtaacag ctacagcgac agcctgggac gctattcacc agtctaatac
     4381 gctagatggg gcaaccattg tcaaattaac cagaacgctg gctattattc ccataacgct
     4441 tggcttatct atttaccaaa ccaagagcag gcaggcacat acgacagagg gttcctttag
     4501 cctcagaaag gcttttccga cctttattgt ctttttcttg ctagcttcct tgataaccac
     4561 ctttgctgct agcttaggtc tgccaatggc aatctttcat cagcttaagc tactctcaaa
     4621 attctttatc gttatggcca tggcagcgat tggactcaat accaatctag tgaccttagt
     4681 caaaactggt ggtaaggcca ttttgctggg tgggatttgc tggctagcga tcacatcagt
     4741 tagcttagca atgcaggcag ctttggggag ctggtaactg atgagaatag ctggtgatac
     4801 gctgctttat aggaaaagca aagcccttgc ttctcctaaa aaagcttgtt agagcagctc
     4861 acttagctgt taagtgtggc ttgatggggt gtgagtagga tctattagtt agaaaagcca
     4921 tcagaacaaa cactatcatt aagctgaagc cggggaaacc cggcttttac gttatgcaga
     4981 attgtctaca tattgaatag gataatccat tttaaaaacg ttttcatttg atagaataca
     5041 attatagctt ggttattagg gtaaacgaga ttgaacttct tatctggttt agcttaagta
     5101 aaagagcagt tggaggaagc atgaaacgta aatttttaat aggtagtcat gggaaaatgg
     5161 ctagcggtct gaaaagctct attgacattt tggccggtag aggtcaggaa ttacagatca
     5221 ttgatgctta tattgatgat agtgattata ctgagcaggt attgaccttt atcgaagatg
     5281 tagcagctga cgagcaggca ctgattttta cagatttatt aggtggcagt gttaatcaaa
     5341 aaatagtaac tgccctaatg aacagtggca aggaaaatat ctttttgatt tcaaatagta
     5401 accttgcagc cttgctatcg ttgatgtttt taaagccaga agaagagctg acaaaagacg
     5461 agattgtagc aacgattaac gattctcagg tgcagctggt ggatctagct ccagcgacag
     5521 ccgcagaaga tgactttttt aattgaggag gaaaaaagaa atgattacac aaattcgtgt
     5581 tgacgacaga ttgattcatg gacaggttgc tgttgtttgg accaaggagc ttaatgcccc
     5641 tttgcttgtg gtagctaacg atgaggctgc taaaaatgag attacacaaa tgactctgaa
     5701 aatggcagtt cctaatggca tgaaattatt gattcgctct gttgaggact ctatcaaggt
     5761 tttcaatgat ccacgcgcag tggataagcg tatttttgtc attgtcagct ctatcaagga
     5821 cgcttgtcag attgcaaagc aggtgaagga tttagaggct gttaacgttg caaatgtagg
     5881 gcgctttgac aagtcagacc cagcaactaa ggtcaaattg gcttcaagcc tattgttgaa
     5941 tccggctgaa ttagaagcag caaaagagct cgttagcttg cctaacctag atgtctttaa
     6001 tcaagtgtta ccgtctaata acaaggttag cctgagtcaa ctcatcaaat aaagaaaggt
     6061 gtaataacta tgttagtacc agcaacaatg gcagccctag ctgtattgat ttgtttcggg
     6121 ggaaattatt taactggcca aagcatgatg gaaagaccac tcgtggttgg tctagtgaca
     6181 ggcctgctct taggagatat gaaggtcggt atcttgatgg gagcgtcact agaggcactt
     6241 ttcctaggaa atgttaacat tggtggtgtc attgcagcag agcctgtaac agcaacagct
     6301 atggcaacga cctttaccat tatttcacat attgatcaaa aagcagcaat gaccttggct
     6361 gttccgattg gcatgctagc agcctttgtg gtcatgtttt tgaaaaatgt ttttatgaat
     6421 atctttgcgc caatggttga taaggcagca gcggcaaacc atcagggcaa gcttgtcatg
     6481 ctgcactatg gcacatggat tgtctattat ttgattattg cctctatttc ctttatcggt
     6541 atcctggttg gaagcggacc tgttaacgcc tttgttgagc atattccaca aaatctgatg
     6601 aatgggctaa gtgcagctgg tggtcttctt ccagcagtcg gatttgccat gctaatgaag
     6661 ctcttatgga caaataagct agcagttttc ttcctattag gctttgtgtt gacagcttat
     6721 ttgaagctac cagcagtagc tgtggctgca cttggtgcag ttatctgtgt gatcagctcg
     6781 cagcgtgatt tagagttaga tgctattact aagggagcta tcagtaacca aagcagcttt
     6841 gactctaaag aatcagaaga ggaggacttc tttgcatgag atctcaagac aatttaacta
     6901 aagaagaaag aaaaatgcta cgctctgttt tctggcgttc atggaccatg aatgctagtc
     6961 gtacaggagc tactcaatac cacgctgttg gggtcatcta taccttgttg cctgttatca
     7021 atctctttta taagacagac aaggataagg cagacgccct tgttcgtcat accacttggt
     7081 ttaatgcgac catgcatatc aataacttta tcatgggctt ggttgcctca atggaaaaga
     7141 aaaatagtga ggatccgacc tttgatgcca gtgcgattac agcggtcaag gcttctctga
     7201 tgggacctat ttctggtgtc ggagattcct ttttctgggg tattttgagg gtcattgcag
     7261 caggtattgg gatttcactt gctagcacag gctcagcgat gggagcagta gtctttttac
     7321 ttctctataa tattcctgct tttatcattc attattatag cctttatggt ggctattctg
     7381 ttggtgctgg ctttattaaa aagctttatg agtctggtgg tattaagatt gtgaccaaga
     7441 cctcaagcat gcttgggtta atgatggttg gctccatgac agcttcaaat gtgaagttta
     7501 agaccatttt aacagttgct gcaaagggag ccaaggaagc agcctctatc caaaattatt
     7561 tggatcagct ctttattgga attgtccctc ttttggtaac catgaccgcc ttttggcttt
     7621 tgcgtaagaa ggtgaacatt aactggatta tgtttggcat tatgctattg ggtattgttc
     7681 ttggtctttt aggtatttgc taataatctc ctagcatcaa ggataggtaa ggcagggact
     7741 tcttgctttg cttatccttt tttgtagtga gggctgctga aatagcttat gaatttgtta
     7801 gatagattaa gattttctta gctttaagaa atgatttggt ataatagaag gaaataaggg
     7861 gaaaaggctg cctatggaag aaagatttaa aaagcgattg caggatgata tttcacatca
     7921 tttttcacac caatcattga ttttgtccat tttactgatc ggactctttc ttgttttttc
     7981 cttggcacct cagcaaattg ggctatatca agatttgaag gctgttgaac atagctatca
     8041 ccagctgatt cggcaaaata aggcattttt aacggagctc aatcagcata ttctgaccaa
     8101 atttgtgaat catcagctga gctcttctga ccttagcaag caatattatc acctaagaaa
     8161 ccgctcacaa agccaatcag agctgctggt ttttgatgct aacagtcaca tgctgtttgc
     8221 tagtaatcag catctgggaa atttttttcg caatgctgtc tatatgacag aagtcttaaa
     8281 aaaagcaagg caaaggagta gcctcttgag gatcagtatg gataatgagg aggggcatca
     8341 tttactgctg ataaagccta ttaaggtaga acatcaggtt aagggctatt cgcttcttgt
     8401 gatgaatggt aaggattttc ttcagctctc acatcagatt gcttcagatt ttgtgattgc
     8461 agatcagctt gacaatagct ttgcctttac caatcggacc tttatgacct caagtctgaa
     8521 taagcttgac agccattttc ttaagggcta ttttatcttt catgagcatc gtgcctttat
     8581 cctaagaaag gtcgctctta gtccttctat cactctttac agctaccgcc ctttgattcc
     8641 agtttctatt gcgctcttgt tttcattgat gtcctctgtc atgatttatg ctattttata
     8701 ttggaagtcc aaggctctgg cgacacagat tgcttctagc aattcagcag cgatcaatca
     8761 gatggttctt gatatgcagg ccatctcaag gcaggaaaaa agtgccattg acctgcaaag
     8821 tcaagacgaa tttcaatacc tgtcggttca gattaatcag atgattaacc gattgcaggc
     8881 acttcatcag aagaccctag ccttagaaaa gcaaaatgtg atttttgaaa aacgcatgct
     8941 ggaagctcaa tttaaccctc attttctcta taatacactt gaaacaattt tgattacaag
     9001 tcattatgac agtgacctca cagaaaaaat tgtccttcag ctaaccaggc tgcttcgcta
     9061 tagcttagac gaatcacagg aggctgtgtg tctgggagag gatttggctg tcttagaatc
     9121 ctatctgttg attagccaga ttaggtttga agagctgcgc tacacgatag ttgttgaacc
     9181 agccctagag accctaaggg ttcccaaatt atttttattg ccattgattg aaaatgcgat
     9241 caaatatggt ctgcgctatc gccatgacct tgtgattgag atcagtgtga gacagcttgc
     9301 tgatggaatt tactttactg tagcagataa cggtcctgga attagtcaaa aaaggcaggc
     9361 cgatattaaa gagctcttgc attcagagga ttcacatcat ggcttggtca attcttatcg
     9421 tcgactcaag catcaattta caaaagttga attgatcttt tgtcaaagag acgagcgctt
     9481 tttgctaacc tatgtggtta aggagtaaca gatgtataag ctactaatcg ttgaagatga
     9541 gcatattatt cgcaaatggc ttcgttatgc gatcgattat catgcgctaa atatccttgt
     9601 tatcggggaa gctaaggacg gtcagcaggg ggctaggctg attgcagagg ctaagccgga
     9661 tattgttttg acagacatta acatgccgat tatgactgcc tttgagatgt ttgaggccac
     9721 aaaagagcag tcctatgcta aaatcatttt gtctggctat gctgatttcg ctaatgcaaa
     9781 gtctgctatc cattatggtg tgcttgagtt tttgaccaag cccttggaaa ggcaggcctt
     9841 acatgattgc ttgctaacta ttatccaaaa gctgcaacag cagtctcaag agcaggagct
     9901 aagccagcag caggattacc tcaaactgcc acagcctaat gaccaattgc ctgatgttgt
     9961 ccaagaaatg ctcagctgga tccatgagca ttaccaggat aaaatcatga ttggtcagtt
    10021 ggctcacgat ctgggctata gcgaaagtca cctctatcat ttagctaaaa aatacctgaa
    10081 aatgactttt agtgactata tcaaccaata ccgcctgaat cgagcaattc aattgctgat
    10141 tgctgagccg gatgtgatgg tttatcagct tgcagaggct gttggcattt atgactaccg
    10201 ctattttgat cgtgtgttca aaaaatattt aggacaaacg gtcaaggatt tcagagaaac
    10261 ggtattacac cagggatcag ataggagttc attgtgacaa gaaaaacgct gctattagca
    10321 atggtaatag tgatactagg tgtgattggt tctggcttgt atgctatctg gaggcatcaa
    10381 gcaggaccag ctcccagcaa accaagagaa ttggttgttt tgacccccaa cagtcaaaat
    10441 atcctaacag gtacgatccc agcctttgaa gaaaaatacg gcattaaaat ccgtctgatt
    10501 caaggaggca caggccagct cattgatcgc ttgcaaaagg acaaggacca gcttcatgca
    10561 gacatctttt ttggggggaa ttacacacaa tttgagagtc ataaggagct atttgagcca
    10621 tacctttcaa agcatattgg ctttgtattg ccggattacc tgctgcaaag cgaggtcgca
    10681 accccctaca cgcttaatgg aagtgttctg attgtgaata atgaattggc aaaggacatg
    10741 gttattacca gctatgagga tttgctaaag ccagagctaa agggaaagat tgcttttgca
    10801 gaccccaata cctcctcgag tgccttttct cagctgacca atattctctt agccaaaggg
    10861 ggctacacta atcccaaggc ttggagctat atcaagcagt tgatccatag catgaattcg
    10921 atcaaatctg ctagctcatc agatgtttat cagtcagtag cagaaggaaa gatgaccgtc
    10981 ggtcttacct atgaggaccc ctgtgttaac cttttaaaga gtggtgccaa cgtttctatt
    11041 gtgtatccaa aggagggaac ggttttttta ccctcagcag ttgccattgt taagcaatct
    11101 aaggccaagg ctgatgccaa attgtttatt aattatatgt tgtctttaga tgtgcagcgg
    11161 gcctttggtc aatcaactag taataggcca attcgaaagg acgctaaggc cagtcaagac
    11221 atgaagcctt tagatgacat tgtcacgcta aaggaagact atgattacat cacaggacat
    11281 aaaaaggata ttttagaacg atacaatcaa ttgagaaaga ccactgacta aatggctttg
    11341 ttatatgaaa cagttcatgc tgtgctgcac ctgaatcgtt agctgctttg tctagctttt
    11401 tgaggtcaat ctctgcttgg gctgtttttt atgttaccat aacccaccgt atttgttcag
    11461 aaagtcaagc gagatcttaa tagccagtta taataggtct ttgagaggga gtctgagctt
    11521 gcttgaggtg gcaagaagat ctgttttgaa gtcaaatggc tgaatttttg gtaaaatgat
    11581 agcatgaatg aactgataaa acacaagcta gagcttttgc cagatagtcc aggctgctat
    11641 ttgcataagg acaaggctgg cactattatt tatgttggca aggccaaaaa tctgagaaat
    11701 cgcgtacgct cttattttcg aggaagccat gataccaaga cagagctgtt agtttctgaa
    11761 atagctgatt ttgagtttat tgtcacagga tcaaatacag aagcactctt attggaaatc
    11821 aatttgattc aagagaacat gcccaagtac aatatcaagc taaaggacga caagtcttat
    11881 ccctttatca agatcactaa cgagccattt ccaagactat taatcacacg tcagattaaa
    11941 aaaaatgacg gcctgtattt tggtccctac ccagatgctt acactgccac tgaggttaaa
    12001 aagctgctag accgtatttt tccctttaaa aaatgcaaaa accctgttaa caaggtctgc
    12061 ttttactatc atttagggca atgtcaggct cacacgattt gccatacaga caaggcttat
    12121 tgggacagct tagttgctga tgtcaagcag tttttaaacg gtaaggacga caagatcatt
    12181 gatgatttgc gctccaagat gcttgaagct tcgcacaatc aagaatttga acgggcagct
    12241 gaatatcgtg atttgatttc aggtattgcc accatgcgaa ccaagcaaag ggtgatgagt
    12301 aaggacttgc aggataggga tatttttggc tattttgttg ataagggctg gatgtgtgtg
    12361 caggtctttt ttgtccgtca gggtaagctc attcagcgag atgtgaatat gtttccttat
    12421 tacaacgaag ctgaagagga ttttttgacc tatgtcgggc aattttatag cgaccaacgg
    12481 catttgattc ctaaggaaat ttttattcca gagatgattg atgagacctt ggttgcagcc
    12541 attgttccag caaggattgt caagccgcag cgaggggaaa aaaggcagct ggtcgcctta
    12601 gcaactaaga atgctcgggt tagccttcag caaaaatttg atttgctgga aaaggattta
    12661 agaaaaacaa gtggtgctat tgagcatctt ggtcagctgt taggcattga aaagcctgtt
    12721 cgtattgagg cctttgacaa ttcaaacatt cagggcacaa gtccggtagc tgcgatggtg
    12781 gtttttgtcg atgggaagcc cagcaagaag gactatcgca aatttaaaat caaaacagtg
    12841 attggtccag atgattatgc gagcatgaga gaggtgattt atcgtcgtta cagccgcgtg
    12901 aagcatgaag ggctacaggt acctgatttg attattgttg atggtgggca ggggcaggtc
    12961 aaggctgctc gcgatgtcat tgagcaccag ctaggcctta gcattccagt agctggcctg
    13021 caaaaaaatg acaagcacca gacccatgaa ttgctttttg ggaacccctt ggcagttgtt
    13081 gagctgccga gaaattcaga agagtttttt ctgctgcatc gtatacaaga cgaggttcat
    13141 cgttttgcca ttacctttca tcggcaggtc aggagtaaaa atgccttttc atcaaagcta
    13201 gatcacattg caggcttggg gccaaagcgc aagcagctac tgctcaagcg gtttaaaagc
    13261 atgactgctc ttgaacaggc tagccttgaa gagattcagc agctagggat tccaaaaacg
    13321 gtcgctgaag cgctgattga tcaccttacc tcaaaaagtg acacctgaat ttgccttatc
    13381 aggagcccta acagtctgaa ttttcttgac aaaagtgaaa aaatagctga aaccagtttc
    13441 aaaaaatgat agaatgatac tacaacataa aagaattaga taggaagcat ttgcagtgaa
    13501 atttctcgaa ttaaacaaaa aacgccatgc tattaaacgg tttaacgaca agccagttga
    13561 ctataatgac ttgcgaacag ctattgaggt tgccactctg gcaccaagtg ctaacaatat
    13621 tcagccttgg aaatttgtca ttgttgagga aaaaaaggca gagctggcaa aggatctgcc
    13681 gttggctaat aagactcagg tagagcaggc tcagtatgtt attgccctgt tttctgatac
    13741 cgacctcatt cagcgctctc gtaagattgc ccgcattggg gtcaagtcct tgcctgatga
    13801 cttgattggt tattacatgg agaccctgcc gccacgtttt gctaccttta ctgagaccca
    13861 aaaaggcgaa tatctggcca ttaatgctgg cttggtggcg atgaatttgg tccttgcctt
    13921 aacggatcag aaaatggcct caaatattat tttaggcttt aataaaaagc taactaatga
    13981 gattttagat attgatccac gctttcgtcc tgaattattg ataactgtgg ggtatagcga
    14041 tgacaagcca gagcctagct atcgcctacc agtggacgaa atcattgaaa gacgctaaga
    14101 tacacaacta ctcgtccagc tagcctataa gtttttggat ttaggaggat agcgaggcaa
    14161 cacataaagg agaaaaagat gacaacaatt gattttaaag cagaggttga taagcgcaag
    14221 gaagctatgc tagaggatct atcaaaccta ttaagcatta attccgagcg agacgatgct
    14281 aaggcagatg ccaagcaccc atttggtcct ggtccggtta aggccttgga gttctttctt
    14341 gccatggcag agcgtgatgg ttaccaaacg cgtaatattg ataactatgc tggtgatttt
    14401 gaatttggtc agggagatga ggttttaggg atttttgccc atttagacgt ggtacctgct
    14461 ggtagtggct gggaaacaga tccttataag ccggtgatta aggataatcg tatctatgcg
    14521 cgtggttcat ctgatgataa ggggccaacc atggcttgct attatgccct gaaaatcatc
    14581 aaggaattag gcttgccagt ttctaaaagg gttcgcttca ttgttgggac tgatgaggag
    14641 tcaggctggg gtgatatgga ctattatttt gcccacaatg gcttgaagaa ccctgatttt
    14701 ggtttttcac cagatgctga atttcccatt atcaatggtg agaaaggaaa cattacagaa
    14761 taccttcatt ttgctggtca aaatgctgga gcttttgtcc ttcatcgctt ccaaggcggt
    14821 ttacgtgaaa atatggttcc tgaatcagcg acagctctga tcagctcacc gcatgagctt
    14881 aatgttatcg aagcttcttt ggagcaattc ttatctgagc acgcagtgac aggatctgtc
    14941 aaagaggctg atgggctatt ggaagtgacc attattggga aatctgctca tggctctaca
    15001 ccagaggctg gtgttaacgg tgcaaccctg ctggctaaat tcttaaatca atttagcttt
    15061 gatggcgcag ccaaggctta tttgcatatt gcaggcgagg tgcttcatga ggatttcgca
    15121 gcagaaaagc ttggcttggc ttatacagat gacaaaatgg gtgcccttag catgaatgca
    15181 ggtgtcttta gctttgctaa ggattcagat gacaatacca ttgccttgaa tttccgttat
    15241 ccaaagggaa ccaatgcggc agtgctaaag gcagggcttg agcagttacc aggtttgact
    15301 aaggttacct tatctgagca tgaacacacc cctcactatg tgccaatgga cgatgagctg
    15361 gtctcaaccc tcctatccgt ctatgaaaag caaacaggac tcaagggcta cgagcaggtt
    15421 atcggtggtg gcacctttgg acgcttactt gagcgtggtg ttgcttttgg tgcgatgttc
    15481 ccaggtgatg aaaacacaat gcaccaagcc aatgaataca tgccattaga caatatttac
    15541 cgatcagctg ccatttacgc cgaagctatt tatgaattga tcaaataaga gattgaacaa
    15601 gctctctgtc taagatgagc cttgctaata ttaacgaata aaagccttat gaagtcagtc
    15661 gtttaatgag acttcataag gctttttgtt tggcgtcaag ccattattta caaagagaaa
    15721 tgccacagtg gatcatcttt tgaaaagtcc ttgtaagaac agacgtaaaa ctagctttaa
    15781 aggagacatt gataggcagt catgcttatc aagaggtctt gtctagcagt tatggcaaaa
    15841 agatcaatga actattattt tccaaggcag aactgactga acaattgagt gattaattca
    15901 tcaggtgcgg catcgcctgt gatttcccct aggatttccc aggctctggt caaatcaatc
    15961 tgtaagagat caaccggcat tcctaaagca agtccttcat tgacagcctc taagctttgt
    16021 actgcctgct caatcaagga aatatgacga gcattggata ggtaagtcgc atcttgctct
    16081 attagcccag tatgatcaaa gaaaagctgg ttgatccggt cttcaatcag gtcaatattt
    16141 tggttttgca aaactgatat tgggatcgcc tcttctggaa gctggtcttt ttcaatgacc
    16201 tgctccagat cggttttatt gaggagaata atgcgattgc tatcctgact aagggctagc
    16261 agagccttgt cctgttcggt cagcttttcc gaagcattga gaaccaaaag gaccagatca
    16321 gcctcctgta gggctttttt agagcgctca acaccaattt gctctactaa atcatctgtt
    16381 tctctaattc cggcagtatc aactagcttt agtggaattc ccttgatatt gacatattct
    16441 tcaatgacat cacgagttgt tcctgcaata tcagtgacaa tggccttgtc ctcacgcaac
    16501 aaggtattga gcagactaga ctttcctaca tttggtcggc cgataatagc tgttgacaag
    16561 ccctcacgca ggatctttcc gcgcttggca gtgcgtagaa gctgctctaa aagtgcctga
    16621 aattcttgtg ttttgtcacg caaaagagca gtggtcattt cttcaacatc atcatattcg
    16681 gggtagtcaa tattgacctc aacctgggct aaggtattta ggatttcttg acgtgtgttg
    16741 gtgatgagct gtgataagga gccatctagc tgcttgatag caatagacat ggccttatca
    16801 gtctttgcac ggatcagatc cataaccgct tcggcttgtg tcagatcaat acggccattt
    16861 aaaaaagcac gctttgtaaa ttcgccgggc tctgccattc gagctccctg tttaatgagg
    16921 agctgtaaaa tgtcatttgt cactgcaata ccaccatggg tattgatttc aatcacgtcc
    16981 tctctggtaa aggtttttgg cgctagcatc accgaaacca tgacctcatc aatcacctca
    17041 cctgtgcttg gcctgataat atgaccatag ttaagggtat gtgaggcgac cgttgttaga
    17101 ttctttcctt taaagatcga tttagcaatg tccagagcct tagtaccaga caagcgaaca
    17161 atgccaatag ctccttcacc taatggagtt gaaatggctg caattgtatc aaattcttta
    17221 gttatactca tgccctctat tgtagaacaa gtcagcatag aaagcaaggt attgcattag
    17281 ctgcttgttg tcgtcattct tgtctagtgg caaagcctca aaagcagttg taaacagcta
    17341 aagctatgat taaaaagcct tgtatggtaa gtacaggata aagccaaaaa gctgatgagt
    17401 tttagataaa catacaggct cgaaaagccc tattaaaccg gcagcaacga tcctcgcaca
    17461 gtatagttga cttaactacc tgatgtcatt tccgactgtt tttataatga caaagaaagc
    17521 aggccatatt aaatatccta aacttagtat agaaaatacc ggtaaacagc aataatttaa
    17581 gtgtataa
//
LOCUS       DARYSY010000045        17224 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYSY010000045 DARYSY010000000
VERSION     DARYSY010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17224
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(167..472)
                     /locus_tag="TVR04_001454"
     CDS             complement(167..472)
                     /locus_tag="TVR04_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HEL1270131.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQTHDMKAGGLISISAHQSYHLEAATNCKYLQIEMV"
     gene            complement(474..812)
                     /locus_tag="TVR04_001455"
     CDS             complement(474..812)
                     /locus_tag="TVR04_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1270132.1"
                     /translation="MSLIHKIPTSTVIDLKAEVPIEEDQMLSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSSGDAMVNVLSGVADITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(840..1595)
                     /locus_tag="TVR04_001456"
     CDS             complement(840..1595)
                     /locus_tag="TVR04_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1270133.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLIQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAVIDQL
                     RDTINVNVSPLQLDAWRQLLVNSGFTAVNYSYGNMTLMSPLGMIKDEGIVDAIRIMLR
                     GMKKENRRQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            1855..2310
                     /locus_tag="TVR04_001457"
     CDS             1855..2310
                     /locus_tag="TVR04_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1270134.1"
                     /translation="MEYDTLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTRLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            2294..2944
                     /locus_tag="TVR04_001458"
     CDS             2294..2944
                     /locus_tag="TVR04_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1270135.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            3054..3959
                     /locus_tag="TVR04_001459"
     CDS             3054..3959
                     /locus_tag="TVR04_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1270136.1"
                     /translation="MKTVHIFYNPNSGKPENDLAEKVKHYLIQNGFSEDKVQIITPKN
                     ADQAFQLAKKSSQDHIDLVIPLGGDGTLNKIIGGVYEGGAHSVIGLVPSGTVNNFAKA
                     LNIPLQLTEALETILSGTIKKVDICKVNKGYMISSLTLGLLADIAANVTTEEKRKFGP
                     LAFLKDSIKILKRNRTYAISLISHHHVLHLKTKFLLITTTNTIAGLPSFSPGAQADDG
                     LCQVYTMSRLSFLKCLRHIRDFRRGDFSKVKEISHFQADSLKLLPQYQRQSAIPRTRI
                     DGDKADDLPVELKVIPKAISIIVSQ"
     gene            complement(4325..4597)
                     /locus_tag="TVR04_001460"
     CDS             complement(4325..4597)
                     /locus_tag="TVR04_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270137.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSKTIEKL
                     NHYIQEKGEQLIETASDKVEASKVAANACGNSAAKAIKGALEVIKI"
     gene            complement(5020..6570)
                     /locus_tag="TVR04_001461"
     CDS             complement(5020..6570)
                     /locus_tag="TVR04_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1270138.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETAAVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKIAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(7242..7802)
                     /locus_tag="TVR04_001462"
     CDS             complement(7242..7802)
                     /locus_tag="TVR04_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1270139.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(7780..8649)
                     /locus_tag="TVR04_001463"
     CDS             complement(7780..8649)
                     /locus_tag="TVR04_001463"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1270140.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKSFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKHQLPF
                     VLDPIMADKGRVYAQLTPQHLPAMRLLAQSAQLILPNVTEACLLADTPYLGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATGRVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEAELGSLGAAFR
                     RLLEEKDDIKTID"
     gene            8740..10011
                     /locus_tag="TVR04_001464"
     CDS             8740..10011
                     /locus_tag="TVR04_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1270141.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGDKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELRKALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRRHILLETPTYHRMEQLAISLGLPYQTIERDFNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKQEKESIVRLAEQYQVYIVEDDYLGDFAPHSELPLHYYDTQQRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQIRQFFNNRAHDLLDFLQKHLPSLAYQLTPQALIIQLDETVNRKGLLKPHHAQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(10047..10385)
                     /locus_tag="TVR04_001465"
     CDS             complement(10047..10385)
                     /locus_tag="TVR04_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270142.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(10485..11573)
                     /locus_tag="TVR04_001466"
     CDS             complement(10485..11573)
                     /locus_tag="TVR04_001466"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1270143.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYVPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIHETLAQYDQIINQGLSPKEVEASILPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDSSVSFD"
     gene            complement(11976..13553)
                     /gene="cls"
                     /locus_tag="TVR04_001467"
     CDS             complement(11976..13553)
                     /gene="cls"
                     /locus_tag="TVR04_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1270144.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMTELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(13767..17123)
                     /locus_tag="TVR04_001468"
     CDS             complement(13767..17123)
                     /locus_tag="TVR04_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1270145.1"
                     /translation="MTKKYHSKKSLLCQLTLATTSILLLHSQTVFAEEQQGSDASVSQ
                     ASPVVAVEATATGDNSQAAASNQAASEIEAKEEKVLSAFAEGTESSAPTNLSLNDSVN
                     AKALQEQTQKGSGAVIAVIDVSFDPEHDAFKLDSDLKNSGTIPAKEAFLAKKQDQHIT
                     YGKWYNEKIIFAYDYTKQSDDIGGLTADNGHGNHTAAIAAGNGKTPAGNGLRVEGIAP
                     NASLMLMKVTGAPERDQFAKSYAKAITDAVNLGATVISMSFGKTADSLSTVHEDVKKA
                     MAYAQEKGVLLVAGAGNESAVGMGTREPLAANPDFGTLNSPAIFEEVISVAASNPVYA
                     ISQSVNAKTADGSQKLAIFMSEGDSFDADQDYFVADAKFGEASHFNGSDVKGKVALIE
                     RGGSLSFYQKIENAVKAGASGVIIYNNNALEGSFTIEKASIPKEARIPVGFMSYKDAQ
                     ALKAGHSFTFNKAYEKMPNNAGGRVISQSSWGVTAEGHIKPDISAPGVNVYSAVHGNQ
                     YDYKTGTSMSTPVVSGLVAMLHKAYKQKFPELSDKELSQLVRAVLMSSARTLYSAESK
                     AYISPRQQGAGEVDGQKALAASYYLTDQKQNPKINLGNITDEFVINLNVNALSKNQGP
                     KKLYFQVNLITDQTKDGHFTLQPKALKDSEWQEINITEDQQHIQVSVDAKAYAAELLK
                     VMPNGYFLEGFVRFTDNLETKEELMSIPFSGFRGDFANLPALDTPIYETLEQGAFYQK
                     LEQDPETGKYILPEKFSKLTALIGQVSPYFLSQDTKNGTVNELGPEAERYIILGTQES
                     ADQKDLIAKEANRTFLISPNDDGNKDFILFQGVFLRSVKDIKAQVLDHQGQVVWESDV
                     ATAQKYYQAGAVLPYRFEHTKWSGKDANDQPVADGSYTYRVWYTPIADGAEAQKQDFK
                     VQVKTSLPELPKSASYDESTRTLKIDASNFPAYRIQVGHIVEIGEGEEADIVINYFQL
                     AEDGTVIIPKTVTSELSGEEVEVDMAALKVIVEDEFGNFNAIALADLLKQKEPEIKDD
                     KQPEPETPMPEQPKGNDSSKEQQSPKGNNSGSKQPLVMKQDSAVKPMTSSPSHELPKT
                     SEKQGSSLLAGLGMLLASLSLGLFKKKSDN"
BASE COUNT         5075 a         3906 c         3164 g         5079 t
ORIGIN      
        1 ctttttatca tcaaaacagg taattgttat tattattaat cactttgagt gatttgaagt
       61 aagctagatc ttcagctaaa ccttatgaca ctaaacacaa aaagccccct aagaccgcta
      121 aaacaccagc ctagggggca agatttgaga gagtcactct atacttttag accatttcaa
      181 tttgcaggta tttgcaattt gttgcagcct ctaaatgata agactgatga gcagagatac
      241 tgatcaagcc acctgctttc atgtcatgag tctgatccgt aagactgacc agcaatcttc
      301 cttctaagac aagcaggagc ttaccttcag ggcttgactc gttgctaatc gtctcaccct
      361 gatacatggc atataaaaca acagattgct taaagcctag gctttgatga agtgaacgac
      421 tagctatttg gtcatcatga taccttacta attctagtaa atcagccaac atgctaagcc
      481 tccggcttta caacaactaa aagcatttgg aaggcttcct tagcaaataa gctatgagga
      541 atattagcag gcatgatgat cgtctcacca gcagctacct cataacaagc ttctccaata
      601 gtaatgtcag ctactccact taacacgtta accattgcat ctcctgatga tgaatggcga
      661 ccaatttctt gtcctttatc taatgaaaac agggttatgc ccaaatcttt tctttgaact
      721 agtgtccgac ttaacatttg gtcctcttca atcggcacct ctgcctttaa atcaatgact
      781 gtgcttgttg gaattttatg aatcaatgac atgtcacttc tcctttatca ttattctagt
      841 tatttttgac ttacagcagc aatataacac agctttcttc cagttttgtt gaaaaaatga
      901 cgcatcttta aaaactgcct tcggttttct tttttcatgc cgcgcagcat aatacgaatc
      961 gcatcgacaa tcccttcatc tttaatcatg ccaagcgggg acatgagcgt catattacca
     1021 taggagtaat tgactgctgt gaagccactg tttaccagca attgcctcca ggcatctaac
     1081 tgcaatggtg atacgttcac attaatcgta tctcttagtt gatctataac agcctttgtt
     1141 tcatcagctt cataggaaac gtcatgcgtc agtaggcgac cacctggctt taaaacacgc
     1201 caatattcct taagcgcttt ttcctttgca gcatcattca acatggttag catagcttcg
     1261 ttaataacga tatcaaagct attatctgca aaaggcagct tcaaggcatt agcttgagta
     1321 aggtgaatat agtcttgcat ttgagctgcc tcaatagcct ttcttgcctc cgccagtacc
     1381 ttggtatcca aatccactgc tgtaatatga cactgataag tctgtgccag ctcaatggag
     1441 gtcgtacaac ggttgcaggc cacctccaag accttgcaat cactcgaaaa ctctccttgc
     1501 tgaatcagcc aatttgtcgc ctcaacacca ccaggccgta gtcgtttctt tcccagtcga
     1561 gctaaaaact ggtgaccaac ttctttttga gacatcacac gccctcccat tgctctgcta
     1621 tatattctta cttagaataa actaactgtt aacaaattga tcaataaatg attactacaa
     1681 ctatatcaca cttcaggcat atcctcaatg aagctttagt gtttctaatg attgttttta
     1741 tggtaaatca taggattgga tcatatttct tgtgctatac gaccttttta cttgctattc
     1801 ttttttgaaa aatatataat ctagttatca aaactagata aagaggtttt agtgatggaa
     1861 tatgatacgc tgccaagctg gaaggatcta cctgatttgg agctatactt ggatcaagtg
     1921 ttgctctatg tcaatcaagt cacacaattg agtcaggcca cagaccataa gctattaact
     1981 gcttcaatga tcaataacta tgtcaaacat ggctatattg acaagcccat taagaaaaaa
     2041 tatcagaaaa agcaggttgc ccgcttaatt gctattagca ttttgaaaaa cgtatttccc
     2101 attcaggata ttagtcaggt cttgacgagg ctacaagcag cctccagctc agaggtcttg
     2161 tacgatacct ttgtcaacta ttggaataat ggccttaccc aatcaacgcc tgaaattatt
     2221 agctatgctt gtcaaaccgt caaggactat cagcacacaa tgaagctttc aagagaaatg
     2281 gaggatacca agcatgaacc aaacctttaa acaaagtctc ccactatcag ttaatgaaga
     2341 ggtcgcaaat agtgtgacac acgctattgg agcagctgct atgctgatac tgctacccat
     2401 cactgctatt tactcttacc agacttatga tctcaaggct gccgttggag catctatttt
     2461 tatcatcagc ttatttctca tgtttttatc atcaacgatt taccattcca tgtcctatgg
     2521 aacaactcac aaatacattt tacgtatcat tgatcatagc atgatttata ttgctattgc
     2581 tggtagctat acacctgttg ccttatcctt ggttgagggc ttgttgggct atgtgattat
     2641 catactccag tggggaatca cactttttgg gattttgtat aaaatttttg ctaaaacgat
     2701 taatgaaaag ttcagtcttg cgctttacat tattatgggc tggttggtcg tttttatcct
     2761 gccggtgatt atccaaaagg ccagtctgcc atttggaatc ttgatgctac taggtggctt
     2821 atcctatact gtcggcgcag gcttttatgc taaaaagaag ccctattatc acatgatctg
     2881 gcaccttttt atccttttag cctctgcttt acaggttatt gccattattt tctatatgct
     2941 gtaaaaagta gctgttgcta ctttttaaac gcgagcgctt gcttaccccc agacacctgg
     3001 cttgattcat gctataataa agggcagtaa atagttgaag ggatcaaagc aatatgaaaa
     3061 cggtacatat tttttacaat cctaattcag gaaaaccaga aaatgatctg gctgaaaaag
     3121 tcaagcatta tctgattcaa aatggttttt ctgaagacaa ggttcagatt attaccccaa
     3181 aaaatgctga tcaagccttt caattagcca aaaaatcctc acaggatcat attgatctag
     3241 tcattcctct aggcggagat gggacactta ataaaattat tggaggtgtt tatgaaggtg
     3301 gtgctcattc tgttattgga ctcgtaccgt cgggcactgt caataacttt gcaaaggcct
     3361 tgaacattcc actccagcta actgaggcac ttgagacgat tttatctggc acgattaaaa
     3421 aagtagatat ttgcaaggta aacaagggct atatgatttc tagcctaacc ttgggtctgc
     3481 ttgctgatat tgcggctaat gtgactacag aagaaaaacg aaaatttggc cccttagcct
     3541 ttttaaagga tagtattaag atactaaaac gaaaccgcac atatgcaatt agcttaatca
     3601 gccatcatca tgttcttcac ttgaaaacca aattcttatt gattaccaca accaatacta
     3661 tagcaggtct tccatcgttt tcaccaggtg cacaagctga cgatggcttg tgtcaagttt
     3721 acacgatgag ccggctatca tttctgaaat gcttgcgcca tattagagac tttagacggg
     3781 gggatttttc caaggtaaag gagattagcc attttcaagc tgattctcta aagctattgc
     3841 cacaatatca gcgtcaatca gccattccta gaactcgcat tgatggcgat aaggctgatg
     3901 atctccctgt tgaattgaag gttattccaa aagcgatttc cattattgtt agccagtaaa
     3961 aaagtgccct agggcacttt ttgatataga ttcatctcca agctgagttt tagaaaacta
     4021 agctatagct gtaacgttag ctgtggcttc ttcttgctgg cttgcagtac tcttttcttg
     4081 tcgtaggaga gctcctcttc ttaggacatc ggctttaagc ctgctttctc aaagaagcta
     4141 tctgactagt ccgacctttt attctcagga caaacatcaa gaaagtgcat gtccttcgat
     4201 tctagagaac cttagctgtc tctgtgtctc attgtaagtg cagctctatt tgactgatgc
     4261 cagctatagc gataagccca gtcgcatatt atagaggatt accaggcgat ttagcttaac
     4321 actcttatat ctttattact tctaaggctc cttttatagc tttagctgct gaattaccac
     4381 aggcattagc agcaacctta gaggcttcta ccttatcaga ggctgtctca ataagttgtt
     4441 cacccttttc ttggatataa tggttcaact tctcaatagt tttagagcct tcctttaaga
     4501 gctctttctt tttagctgag gataagctta aatatgtcac agcaattgct gctgaaccaa
     4561 gaagtaatcc taagccgatt ccatagcttt ttttcatcat caaccctact ttctatgacc
     4621 ttccttaatc atctttttag ctaattttac agctggtact actaaaagca ccaattgtaa
     4681 aagctccata tacttgattt ttcgtcgttt tttcaccatg tgctatttcc tttttcttgt
     4741 ttgcaccata caatcgtctt ttattgcgca gtgccagaga ctgcctgatt aggcagcgta
     4801 agctaagaac tatcagcgtg tcagactagt ctagatacag ctaagcacta gcttgattac
     4861 gataatactt accgctaggc cataagctca gctatcatca aacctaaagt gacaacactt
     4921 tttatttatt atattgtcat tttactaaaa tacacagtta tcgtcaatga ttttgcttta
     4981 ggcagcaaaa atgcccaaga taaagacctt ggacatctgc tacaatgacg ttaattgatt
     5041 gaaatcccaa atatcagtta cccagccctc ataaaactcc ggctcatggc aaaccatcaa
     5101 aatagagcct ttatagactt gcaaggcgcg ttttaactcc tccttagcat ctacatctaa
     5161 atgattggtt ggctcatcta ggattaaaac attgtgctca cgattcatta agagacaaaa
     5221 acgaaccttg gcttgctcac cgcccgagag cacctgaatc tggctttcaa tatgcttaga
     5281 agttagaccg caacgagcta aggctgcccg aacctctgct tgatttaaag caggaaaagc
     5341 gtcccatact gcttctagtg gcgtttgacg cttaacacct gcagtttctt gctcaaaata
     5401 accaagctcc acgaaatctc ctgtttccac ctctcctgac agtggctgaa taatgccaag
     5461 caggctcttt aggagggttg acttaccaat accattagca ccgataattg caattttttg
     5521 atgacgctca aatgttaagt tcaagggatc ttttgttaag ggtctgtcat agccgatgac
     5581 aagctccctt gtttggaaaa taaagcggct tggtgttctt gcttccttaa actcaaagct
     5641 tggctttggt ttttctgcct gaagctcaat gatttccatt ttatcaagct tcttttgacg
     5701 ggacatagcc atattgcggg tagctactct ggccttatta cgattgacaa aatcctgtag
     5761 ctctgcaatc tctttttgct gacgctcata ggctgcctct agctgagctt ttttcatctc
     5821 atagacttcc ttaaactgat cgtaatttcc agaataccta accaaattcc gattatcaac
     5881 atgataaaca atattaatga catcatttaa aaaaggaata tcatgtgaaa tgagcacaaa
     5941 ggcattgtca taatgctgta aatagcgctt taaccactca atatgctcag catcaagata
     6001 attggtcggc tcgtccagca gcaaaatatc tggcttctcc agtaacagct tggccagcag
     6061 gatcttggtt ctttgccctc cagataagga ggtcacctct gtttccatcc caaaatccat
     6121 aacacctaag gcacgcgcaa cctcatcaat cttagcatct agggtataaa agtccctgct
     6181 ttccagacgg tcctgtagct ctccgacctc ctccatcaaa gcatcgacag cagctgtctc
     6241 ctctgccata gacatgtaaa tggcattgat acgctcctct gttttgaata gctcatcaaa
     6301 ggctgtccta agaacatcac gcacagtttg accaggttct aaaacggtat gctgatccaa
     6361 atagcctgct gtaacatact ttgaccattc aatcttacca gcatcaggct gcaagtgacc
     6421 agtaacaata ctcataaagg tggacttgcc ttctccattt gctcctacta atccaatatg
     6481 ctcgcccttt aaaagacgaa aggaaacatc ttcaaaaatg gcacgatcac caaatccatg
     6541 acttaactgc ttaacttcta atatgctcat gattactttc ctttattgtc atcaaaaaag
     6601 ccgttaaaac ggcttacact ctctcaatta tggcaaaaat gcagcctttt gtcaatgaag
     6661 gctgaaaaag cctacgtcat acgcatgaaa gatttttagc aagaacagaa ggttttttgc
     6721 attttaatgt tcagctattt taagaatatg tcttattatt ttagaaactt tactatagga
     6781 aaaaccttaa aagtgcctgc tttaatccct actatcattc ggaaagaact gtttcgctcg
     6841 tttgtcgtgg aaagccgctc acaacaaaga catggagagt ctgagacaac aagagctgcg
     6901 ctttagccat ttttaattga catgctttat tgcccagtct aattcattaa aaagcgaaca
     6961 ggtctagctt ttggaatctc agaaaactag acctgttcat ttgtcttata ttgaggtagc
     7021 cttttgtttc agcctcgtct ttttcaggtt ttcagatcga acttaaggac aaaaaacact
     7081 ctcctgtatc agctaacctt atcattcatt ataaaggaaa atgatttcta atacaaggaa
     7141 ataccgttat ttcattaaaa ataactaaaa atagtttgtc aaatcattag ttattaatag
     7201 gcttagataa caaaaatgat gatactgcta gcaaggttag ctcaaccaag cctattactc
     7261 gcttcttgct tttttactgc ctgccttaat tgcttaaaaa cagggtataa gagaggcaca
     7321 gcaataacgg tcacaagggc agtaccaaga ctgccaccaa ttttgccaag tgctgcccac
     7381 aaagcaacag acaagggcag ctgggcgcca aaataagcaa tcaagctata tttcacaaga
     7441 ttcatgacta attttgctgc tgctgctaac aagccaattg ctacaataat catcggttta
     7501 tcaactgatt tcagaagttt ctcataaatc acatgaagca ggtaacaaac cactaaggct
     7561 tcaagcactg ttatccagac cacagccgca tagccattaa tcatatcaaa cagtcctaga
     7621 ccaatggctg ccaccaaagc tgcccttcta gcaccataca ataaaacagc caccaccact
     7681 aaggcattcc ctagatgaat aaattgggct ccaactggaa tacgcagcag ctcaaccgat
     7741 ataaaaataa gagcagcaaa taggctaagc tcgatctgat cagtcaatcg ttttgatgtc
     7801 atctttttcc tccaataatc ttctaaatgc ggctcccaag ctgcccaatt ctgcttcgta
     7861 ggcaattcca agtgaaagct ctcgatttag cgcaacagta gccgctaacg acttgtctaa
     7921 gaagctaata accatatcca acaactcatc aatagcaagc ctgtgaaaat acccagcgct
     7981 aacaatagca gagacaagat cacccgtacc ataaaagtga taagggtatc gttttccaaa
     8041 atgatagcta accctccctg tcgccttttg ataataagca aagccgatgt gctgatcatc
     8101 aaaggatatg ccagtaagga caatctctct aggtcctagt gtagctaact tagacaatag
     8161 cctctccaaa tcctctctgc tataggtctc tcctaaatag ggagtatcag ctaacaagca
     8221 agcctctgtc acatttggca gaatcagctg cgcagactga gctagtaacc tcatggctgg
     8281 caaatgctgc ggcgttagct gcgcgtagac tctcccctta tcagccataa taggatctag
     8341 cacaaaggga agctgatgct ttttgatgta atcaagaatg atcaaagcat catcaggacg
     8401 gtacaaataa ccagaaaaaa agccatcaaa ggcaagaccc gcttgagacc aagtcgtcaa
     8461 aaatgacttc agcccttctg acgtactctg gatataaggt gtcttagcaa ttgcagtgtg
     8521 gcttgataac aaacaggttg gaagaatggc ctgttcaatt tggcaagccg ccataatggg
     8581 aatactagca gacagagcaa ccttgccaac tccgacaatg tcatttgcaa caataacacg
     8641 ttttaacaac aataagctcc ttcatttctt tttttactat tgtaagaaaa tccttgatga
     8701 gatacaataa ggatagattt catctgtatg gggacactta tgacaagtaa atatcaacaa
     8761 atcattgcag acctagagtt ggccatgcaa tcaaaccaat tcaaaaaggg agataagctc
     8821 ccttctatta gacaattaag tcagcagtat cactgcagca aggataccgt gcaaagagca
     8881 cttttggccc tacaatacaa gcgcctcatt tatgctattc caaaaagtgg ctattatgtg
     8941 cttggtaaaa ttgaggaaaa gcagcattcc tttgagctaa gccttgagga ttataatcag
     9001 ttggcctatg aggactttcg gctctgtcta aatgaagccc tagacggtaa agattctgat
     9061 ttatttaact actatcataa ggctgaggga cttgaggagc tgcgaaaggc tttgctgcct
     9121 tatttggctg ataatgggat ttacgctaac aaaaatcagc tgctaattac ctcaggtaca
     9181 cagcaagccc tttacatttt agctcaaatg agatttccca atggccgccg tcacattctc
     9241 cttgaaaccc cgacctatca ccgaatggag cagctagcta tttccttagg cttaccctat
     9301 caaaccattg agcgcgattt taacggcatc aatcttcatc agcttgaaag catctttaaa
     9361 accggacaga tcgctttttt ctatactatt tctcgatttt caaaccctct tggcctctcc
     9421 tacagcaaac aagaaaagga aagcattgtt cggctggcag agcaatacca ggtttacatc
     9481 gtagaggacg attatctagg ggactttgca ccgcatagtg agcttccgct acactactat
     9541 gacactcagc aacgggtcat ctatctgaaa tcattttcaa tgagcgtctt tcctgcccta
     9601 cgcattggag ccttgctttt acctgatgat ctcaaggaag gctttttgtt acaaaagtca
     9661 atgattgacc ttgatactaa cctgatcatg caaaaggcac tagcattata tttagcaaat
     9721 ggtatgtttc aaaaaaacct aaagcaaatt aggcaatttt tcaacaacag agcacatgat
     9781 ttactagatt ttctacaaaa acaccttcct agcctagctt atcagctcac tcctcaagcg
     9841 ctgattattc aattagatga gacagttaac cgcaagggac ttctgaaacc acaccacgcc
     9901 caaatcatct caacaagaaa agcaaggtat atgcttctaa caatcagtcc tgatatgcca
     9961 tctaagctgc tcgacttgtt ttcagtgaca catgaaaaga cccaagaata gctcattggg
    10021 tctcagtgtc ataaaaatgt caatagctat ttgatctgct cgaatcgtaa atgaacacta
    10081 atgctatcac cgtagccatt tctctccaaa tctctttgga ggcggtaagc aatataatgc
    10141 tctgcaatag tcatgtaacc tgcatcaatc agacgatttt caacaagtga ttgaatcata
    10201 ttaatcgtcg gacgctccgc ctgcacctcc tctagatcaa taacaacctt tttagttacc
    10261 tgagctagat gctgtctcca gctatcatca atcacataca ctgttcttgc tgccttaatc
    10321 aaagcctgat aaatcttatc cggatcaaag tctgccagct gaccgtcacg cttaataatt
    10381 tgcataagag cgcctctttt catttagttt cattgcttac attcattatg caaatgtttt
    10441 catcatttgt caagctatta ggctcctata cctcttagga atgatcagtc aaaagagaca
    10501 ctagaatcaa ataaattgtc ctgtgctggt cggacaagcc cacgctcgtg cagggtctct
    10561 gcaatctgaa cagaattcca ggctgcgccc ttgagcagat tgtcagatac cacccacatg
    10621 tgaatgccct tttcaacatc taaatcctta cgaagccttc ctacaaaggt ctcacgactg
    10681 ccaacagcat taacggcctg tgggtatcgc tgcactccgg tatcgtcctc caaaacagca
    10741 cccggaaatt gtgcaatcgc ctccttaaca gcttcgatag tagctactgc cttggtttca
    10801 atgtagatag attctgaatg ggctgataaa acgggtatac gaacacaggt cgcagacacc
    10861 ttaatcgtat cgtcctccat gatttttttc gtttcatttg tcattttcat ctcttcataa
    10921 gtgtagtcat tttcagtgaa acgatcaatc tgtggtaaag cattaaaagc aattggataa
    10981 tgtctcttgt caccagctga cggtaaaata cttgcctcca cctccttagg agacaagccc
    11041 tgattaataa tctgatcata ctgagctagg gtttcatgaa ttgctgactg accagcacct
    11101 gaaacagcct gataagtaga aacaataata cgctcaagac cccacctttg acgaataggc
    11161 tccagcgcta tcatcatttg aatcgtagag caattagggc aagcaacaag gccttgatgt
    11221 gtatcaagag cgtgagcatt tacctcagga acaacaagtg gaacagctgg gtgctgacga
    11281 aaataagagg tattgtcaac cacaacagca cctgccgcaa cagcataagg gacatatttt
    11341 gcagaaacat tgcctcctgc tgaaaaaagg gctagatcaa tgccttggaa ggctgctttt
    11401 gttagctcct caacaacaaa atcctctccc ttaaatgaga ggatttttcc tgctgaacgt
    11461 gcagaagcca ataatttaat agctgaaata ggaagacttg actcctccag catcttaatc
    11521 atttgctgac cgacagcgcc tgtcgctcca accactgcta ctgtatatcc cataggtcta
    11581 cctcacttta actgatgata atggacctat tatagcctat ttcatcacaa aagaaaagca
    11641 agctaagcta aaagcctatg gcatgacagt caatagataa gtttttcata tcagaactat
    11701 tgtcccatga taacatacac ccttaggaga agcagttatg ctatggatat gatgagagtc
    11761 acatctaaca cagtgagatg aactagatat cacaacataa aaaagctgag agaaactctc
    11821 agctctcagg ggcattcgta tcacgaatgt gataaaaagg ttcacacaaa ttatcaaagt
    11881 cggctcctgc cttaatgacc tccccagcac aactgtgatt taaaaatcac aatcgactca
    11941 tcgcataggt ctattatagc aaacatatca tctctttaca agaggggagc tatcgtttta
    12001 accaatagac caacgagctt ctgataccaa ggtctttgcc ttagctgact ttctgtgact
    12061 agcttagagc ttgcctgggt ttctttgaaa tcctgaacaa tgtctgcaat aacagaggaa
    12121 cgataaaggt aggtggcgca ttcaaaatga tgatagaggc tgcgataatc cagattaatg
    12181 gttccaacga ctgccttaga atcatctgaa ataaagacct tagaatgcac aaatcccgga
    12241 ctatattcgt agattttaac tcctgaggtg atcaagcctt tatagtaggt tttagcaagg
    12301 gcataaggaa cagccttgtc aggcttacct ggcataataa tccgaatatc cacccctcgc
    12361 tctgctgcaa atctgagagc atgctctgtt tcgctatcca aaatcaggta tggagtcatg
    12421 atataaacat attccttagc gtgattcaag atatcaatat agacgtttct gccaattttg
    12481 tcagtatcaa gtggtgagtc tgcataagga atgacatagc catctgaggc gacctcctct
    12541 gtatgctggg atagataagg ctccacgatc agcctttttt cggtaattga ccacatttgt
    12601 aaaaacatga tcaaaaagct atcaacagcc tcacccttta gcataagacc tgcgtccttc
    12661 caatgcccaa agcgtttgac ctcattaatg tactcatcag ctaggttaat accgcctgta
    12721 aaggccacct ctccatcaat caccacaatt ttacgatgat cccgataatt gtaataggtt
    12781 gaaataaaag gcgagatcgg caaaaaagac tttgccttaa taccaatgcg ttcaagtctg
    12841 gcagcataat ccgctgataa ggtcgacagc tctgtcatgc catcaaaaag aacgcgaacc
    12901 tctactccct cttgcacctt cttttctaaa atccctaaaa tttctcccca catctgcccc
    12961 tctgcaatga taaaaaattc cagaaaaata taggacttag ctaataaaag ctgagttttt
    13021 aagccttcaa aaaaggcttc tccaatggga aagtaggttg cttgagtctt gcgataaatg
    13081 ggaaaattcc cacgactacg ctctaaatac tgaacgaggt gataggtcgt tgaggtatga
    13141 cccttcaacg cctgtaaaat agcgtcatca tctctcaagt aaggagaaga caagtcaact
    13201 aaatggttaa ttcgctgctt taggtcacga taaccccagt ctaatttagt gtaaataaga
    13261 aataaagagc ctagtaaagg ggctatcata ataagaatca gccatgtcac ccttgaaata
    13321 gcgtccatat cgctattcac caggtacaag acaattgaaa ttgaaaaaat acgctcaata
    13381 atagcaatta aaacacgata ctgctccatc caagcatagg actggcataa aaagaagatt
    13441 tgcagaacga tcaaagcagc aataatggtt gttctgctaa aaatccccct cagcaatcct
    13501 tttttccctt tatggagcag gtatcttact tttttattct ttttgatagt caaccctcca
    13561 gctttatttt ttcttattat atcataaaac tggaggccat gatttaagct gctgctaaaa
    13621 gtttcagcaa ttagtgcaag cattaaaaaa gacctcaata cttcctttac agcctgtaat
    13681 cctcataaga cctattgcct caaaaactaa aaaagattga aggagatatg attccccttc
    13741 aatccaagtt tcatcaggtg atgagatcag ttatctgatt tctttttaaa taagcctaga
    13801 gataggctag ctagtaacat acctaagcct gctaataatg atgagccttg tttctctgag
    13861 gttttaggaa gctcatggct aggcgatgag gtcatcggtt ttactgcact atcttgcttc
    13921 atgactaacg gctgcttaga acctgaatta ttacccttag gtgactgctg ctccttagat
    13981 gagtcattgc cctttggctg ctctggcatt ggtgtctcag gctcaggctg cttgtcgtct
    14041 ttaatctctg gttccttttg ttttaaaagg tccgcaagag caattgcgtt aaagttacca
    14101 aattcatctt cgacgattac ttttagtgct gccatatcaa cctcaacctc ttcacctgat
    14161 agctcggagg tcactgtttt tggaatgata actgtgccgt cctcagccaa ttggaagtaa
    14221 ttgatcacaa tatctgcttc ctctccttct ccaatctcga cgatatggcc aacctgaatg
    14281 cggtaggctg ggaaattaga agcgtcgatc ttaagcgttc tggtagattc gtcataagaa
    14341 gctgattttg gtagctctgg taggcttgtt ttcacttgaa ccttaaagtc ttgcttttgg
    14401 gcctcagcac catctgcaat aggagtatac caaacacgat aggtgtagct accatctgct
    14461 acaggctgat cattggcgtc ttttccactc cattttgtat gctcaaagcg atacggtaac
    14521 acagcacccg cttgatagta tttctgtgct gtagcaacat cactttccca aacgacctga
    14581 ccctgatgat caagcacctg agccttaatg tctttaacgc ttcttaggaa taccccttgg
    14641 aagagaataa agtccttatt gccatcatca tttggggaaa ttaagaaggt tctatttgcc
    14701 tcttttgcta tcaaatcctt ttgatcagct gattcctgtg ttcctaaaat gatataccgt
    14761 tctgcttcag gacctagctc gttgactgta ccattttttg tatcctgaga caagaagtat
    14821 ggactaacct gaccaatcaa agcagttagc ttgctgaatt tttctggtaa aatgtatttc
    14881 cctgtttcag gatcttgctc aagcttttga taaaaggcac cctgctcaag cgtctcataa
    14941 ataggagtat ctaaggctgg caagttagca aaatcacccc taaagccact aaacggaata
    15001 ctcatcaatt cttccttggt ctctaaattg tctgtgaagc ggacaaagcc ttcaaggaag
    15061 tagccatttg gcattacttt tagcaattca gcagcgtaag ccttagcgtc aacagaaact
    15121 tgaatatgct gctggtcctc ggtgatatta atttcctgcc actctgaatc ctttaatgct
    15181 tttggctgca aggtgaagtg accatcttta gtttgatcag tgatgaggtt gacttggaaa
    15241 taaagctttt taggtccttg atttttcgat agggcattaa cgtttagatt aatgacaaat
    15301 tcatctgtaa tatttccgag gttgatttta gggttttgct tctgatcagt cagataatag
    15361 ctagctgcta gtgccttctg accatctacc tcaccagcac cctgctgacg tggtgagata
    15421 taagccttgc tttctgcgct gtaaagcgtt cttgctgagc tcatcaacac agccctaaca
    15481 agctgagaga gctccttatc agatagctct gggaatttct gcttgtaagc tttatgcagc
    15541 atggccacaa gccctgacac cacaggggtt gacatgctcg taccagtctt gtaatcatat
    15601 tgattgccat gaaccgctga atagacattg acaccaggtg ctgaaatatc tggcttgata
    15661 tgaccttctg ctgtcacgcc ccagctggat tggctgatga cgcggccacc agcattattc
    15721 ggcattttct cataggcctt attaaaggta aagctatgac ctgccttaag agcttgagcg
    15781 tccttgtagc tcataaagcc aacaggaatg cgagcttcct ttggaataga ggccttttca
    15841 atcgtaaagc ttccttcaag cgcattgtta ttgtagataa tcacaccgct ggcaccggct
    15901 ttaacagcat tttcaatttt ttgatagaag ctaagcgagc cgcctcgttc aatcaaagca
    15961 accttgcctt taacatcaga accgttaaag tgagaggctt caccgaattt ggcgtcagcc
    16021 acaaagtaat cctgatcagc atcaaatgag tcgccctctg acataaagat cgctagtttt
    16081 tgactaccgt ctgcggtctt agcattaaca gactggctaa tagcgtaaac aggattggaa
    16141 gccgcaacac tgataacctc ttcaaaaata gctggactat taagggtacc aaaatcagga
    16201 tttgctgcta gaggctctcg agttcccata ccaactgcac tctcattacc agctccagca
    16261 accaacaaaa cacccttttc ctgagcatag gccatagcct ttttaacgtc ctcatgaacc
    16321 gttgataagg aatccgctgt ttttccaaaa ctcatgctaa tcaccgtagc tcctagatta
    16381 actgcgtctg tgatcgcctt agcataggat tttgcaaatt gatccctttc tggggcacca
    16441 gttaccttca tcagcataag agaagcattt ggcgctatcc cctcaacacg aaggccattt
    16501 cctgctggtg ttttcccatt acctgctgct atagcggcag tatggttacc atgaccatta
    16561 tcagcggtca agccgccaat atcatctgat tgcttggtgt aatcgtaggc aaaaataatt
    16621 ttttcgttgt accacttacc gtatgtgatg tgctggtctt gctttttagc aagaaatgcc
    16681 tctttagcag gaatagtacc gctatttttt aagtctgaat caagcttaaa ggcgtcatgc
    16741 tcaggatcaa aggaaacatc aataacagca ataaccgctc cgcttccctt ttgtgtttgc
    16801 tcttgtaggg ctttagcgtt gaccgagtca ttcagtgata aattggtcgg tgctgaactc
    16861 tctgtgcctt ctgcaaaggc tgataggact ttttcctctt tagcctctat ttctgaagcc
    16921 gcctggttgc ttgctgctgc ttgagaattg tcacctgtag cagtagcttc aacagctaca
    16981 actggactcg cttgtgatac agaagcatct gagccctgct gctcctctgc gaaaacagtc
    17041 tgactgtgaa gcaataaaat acttgttgtt gccagtgtta attggcataa taaacttttc
    17101 tttgagtgat attttttagt cactaataaa acctccattt atacctgact ataataatat
    17161 aacaatatct ctttattaac aatagatttg tgaaaaatta attccatcat ttaatattaa
    17221 aagt
//
LOCUS       DARYSY010000046        16907 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYSY010000046 DARYSY010000000
VERSION     DARYSY010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16907
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            211..915
                     /locus_tag="TVR04_001469"
     CDS             211..915
                     /locus_tag="TVR04_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1270146.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTHASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGISEEELARYYHDKTFDPQILSAIKPGARYTKQG
                     FMSTTAIKNAAMPHRSVELRIRVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(973..1248)
                     /locus_tag="TVR04_001470"
     CDS             complement(973..1248)
                     /locus_tag="TVR04_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1270147.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(1346..1933)
                     /locus_tag="TVR04_001471"
     CDS             complement(1346..1933)
                     /locus_tag="TVR04_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1270148.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNTAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTKKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            complement(1911..2753)
                     /locus_tag="TVR04_001472"
     CDS             complement(1911..2753)
                     /locus_tag="TVR04_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1270149.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSNFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNQKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            complement(2746..3585)
                     /locus_tag="TVR04_001473"
     CDS             complement(2746..3585)
                     /locus_tag="TVR04_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1270150.1"
                     /translation="MGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSDNELK
                     EEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTIEASR
                     QGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQSGASLEEILEAVESIKRKTELYIG
                     VSTLEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLDSYLA
                     ENSQRQIAEVAISYAGQRDFADGLKQTIATVFDGPITVLETGSIIQTHTGEGAFAVMV
                     RYE"
     gene            complement(3733..4605)
                     /locus_tag="TVR04_001474"
     CDS             complement(3733..4605)
                     /locus_tag="TVR04_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1270151.1"
                     /translation="MLKKRMGLACLLVLTTFIYQCCSVTAEQYSDTEAEVLQINEEKS
                     QIMESQEVLEGLITSSDQLKKKALKPKEADANKSEQEASTVYLAEDDPVTIDSSDEES
                     NRDIIADSVPDLVIKGDQVDVSEVMVSVKEDPSKVAKQRTNAAQRYSMAKHQLTQKLE
                     AFNTATNQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLDS
                     SATILDELGRVISDISGHKGMLPFNRKISFKAHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANNKS"
     gene            complement(4825..6486)
                     /gene="recN"
                     /locus_tag="TVR04_001475"
     CDS             complement(4825..6486)
                     /gene="recN"
                     /locus_tag="TVR04_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1270152.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIDAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGGDRSSDELERELKALEKQLVLTASQLSDQRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGRYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            complement(6505..6975)
                     /locus_tag="TVR04_001476"
     CDS             complement(6505..6975)
                     /locus_tag="TVR04_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1270153.1"
                     /translation="MKKSERLELIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYIYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            complement(6962..7789)
                     /locus_tag="TVR04_001477"
     CDS             complement(6962..7789)
                     /locus_tag="TVR04_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1270154.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPALCSLLQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVTDTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKENSSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            complement(7782..8651)
                     /locus_tag="TVR04_001478"
     CDS             complement(7782..8651)
                     /locus_tag="TVR04_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1270155.1"
                     /translation="MDKLTRINATIHQHYDRQSTVSADLEEAILYSVDGGGKRLRPLI
                     LLELLEGFGLALTDAHYAVAAAIEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFDEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLVQQFSLASGTFGMVGGQLLDMKGEQQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDV
                     TASFDELGKTPQKDLAVEKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            complement(8651..8866)
                     /locus_tag="TVR04_001479"
     CDS             complement(8651..8866)
                     /locus_tag="TVR04_001479"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1270156.1"
                     /translation="MSTKKTFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            complement(8844..10184)
                     /locus_tag="TVR04_001480"
     CDS             complement(8844..10184)
                     /locus_tag="TVR04_001480"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1270157.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSIIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGVVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANIARANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELVTPITKTDIVSWIAEQQN
                     RSYQACLRYIRQGQERVDKLSYSVMFRQPERLYDAYSQRLDRLTTSLMTTFKETLSEA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGAVAACVKDIKKGDHLSIVMRDGQLEVEVEDVNEKNI"
     gene            complement(10468..11322)
                     /locus_tag="TVR04_001481"
     CDS             complement(10468..11322)
                     /locus_tag="TVR04_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1270158.1"
                     /translation="MIIDQSLVARVVVPRQTESHKGSYGRVLLVGGLYPYGGAIIMAA
                     LACVHSGAGLVTVATDRENIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKKTADTKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQHDAANQAALRRFSRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVDKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            complement(11319..12173)
                     /locus_tag="TVR04_001482"
     CDS             complement(11319..12173)
                     /locus_tag="TVR04_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1270159.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSEMASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            complement(12285..13979)
                     /locus_tag="TVR04_001483"
     CDS             complement(12285..13979)
                     /locus_tag="TVR04_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1270160.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAAHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGADILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYGIETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNKLIERAGAMSLKTVVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            complement(14441..15178)
                     /locus_tag="TVR04_001484"
     CDS             complement(14441..15178)
                     /locus_tag="TVR04_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1270161.1"
                     /translation="MTETVISIRQLHKSFGQHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPDQVFEAPREERTKDFLSKVLS"
     gene            complement(15180..15863)
                     /locus_tag="TVR04_001485"
     CDS             complement(15180..15863)
                     /locus_tag="TVR04_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1270162.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTLMISACVVLFGTAIGVLVTLIKRS
                     HIKPLSWLVSLYVWVFRGTPMVVQIMIAFAWLHFNHLPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            16251..>16907
                     /locus_tag="TVR04_001486"
     CDS             16251..>16907
                     /locus_tag="TVR04_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1270163.1"
                     /translation="MRKPIRKYSVCSAAIALATMASLGTAGNARAEHKELKDYPDPTR
                     RISSKTLGDNEVRKYLHELRDFLKGYLKELEEKAEQPGPMGPAGPAGPIGPKGEAGPQ
                     GEPGPQGEPGPQGPRGDKGETGEAGPKGEQGPAGKPGEAGPKGEPGERGPKGDKGDTG
                     ATGPKGDRGERGEKGEKGQRGEKGEKGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     K"
BASE COUNT         4884 a         4293 c         3165 g         4565 t
ORIGIN      
        1 atttttatta tgtttgttac attaaggaag tttgtaatca tttcaactaa ggctaatcct
       61 gttagcaaca gacatcatca ttaggtgatg acactcttgg cactactgta aaggaggaaa
      121 agctaaatga ctcatcaaca tcataacgca aagttatctt atcaaaggat agctattcgt
      181 acactatgct tgtttacatt tttcttatcg ttgcttgtcg ttcagccttc aaccatcaag
      241 gcacagtctt atgatgaagg acaaacagtt gtttttgagc cctatgggaa tagctttaag
      301 ccttattata aatttagtga gcctgatgtt accaaataca ttatcaccaa tcgctggagg
      361 tctcaaacag cctttacaga agcagaaaaa aagatgatgt atcaatatac acacgcctct
      421 gccagtccta ttaacctagc cctagaacag gtgatgggag ataccagcca actggatgcc
      481 cagctgcaac agtctgtagc cttacttgat agtgctactc ataagctaac catcccttgg
      541 aatatcatcg tctatcgcta tgtttatgaa acattcttaa cagaattagg catttctgaa
      601 gaggaactcg ctcgttacta ccatgataag acctttgatc cgcagatcct atcagcgatc
      661 aagccaggtg ctcgttatac aaagcaaggc tttatgagta ctacagccat caaaaatgct
      721 gctatgccac atcgctcagt ggaattaaga attcgggtcc ctcaaggcag ccaggctgct
      781 tttgtacagc cctactcatt ttatccttat gaaatggaac tcttgttccc aagacagtgc
      841 acattagaaa ttattggcgc taatctttca gacgatcaca caagattact tattgaaaca
      901 agactccttc cttaatggaa aaagccctat ctcacaggct aaacagctta atgagacagg
      961 gattttgatt tattatttta cagcgtcctt aagagcttta ccagccttga atgctggaac
     1021 ctttgaagct gcaatttcaa tttcttcacc agtttgtggg ttgcgacctt tacgagcagc
     1081 gcgttcacga acctcaaagt taccaaaacc aattaattgt accttttcac cttcagcaag
     1141 aaaagcttcg attgcagaaa agacagcgtc aactgctgct gctgaatctt tctttgtaag
     1201 ctcagttgct tctgcaacct ttgcgattaa atcttgtttg ttagccattt aacaatcctc
     1261 caaataatta gtaagcttaa cgctttaaca gatattatca tatctaaaaa acagccacag
     1321 gtcaagtatt aaacgttagt tagactcatt tcttatagat gtcaaatcga atatcatcct
     1381 tgacaagatc aatcttttga gcctttaaat agatgttggc atcattttcc aattgctgta
     1441 gattgataat aatagctgat tgcttaggta agacttcaac gaattttggc agcttatagc
     1501 tggatttcaa gtattgcaaa acgtcctttt ccggcaaaga aagggtcccc acagaaaagg
     1561 agagaacctg cagctgtatc gcaccattgg ttaagcgatg aggctgaaaa taaatgtata
     1621 acggcacctc atatcctaag agctgatagg ttccttcaaa gagaatggtc gaggaggtgg
     1681 catacacctt ataggtcatt tttttcgtct gaaaatcctt taggtagcta acgactgcct
     1741 catttaattg ctctttagtg gttgttaagg tccctatttt aatattcttt gctgcttttt
     1801 gattgatcag ctcagactta ggctctctta tttgtataat acgactgcca ataactgcta
     1861 aaaaggctgt attaaaagcc aataatagca aaaaagccca tttccaccaa ttaaggttta
     1921 atttcttttc cattctttct tattgtctcc attactgcgt ctgacatgat ttgatagcct
     1981 gtattattgg ggtgaaaatg atcccctgaa aacaaagcat cattcacaat cgttgtttgc
     2041 tctcctgttg actggacaat gccctcttta ccatctactc ctttgtacaa tagatcatta
     2101 attggaacaa agtaaacatg gtcatagtca tcaacaacct cttgtgtttt ttggttccag
     2161 tcattaatga ccgtctgcat ttctgttagc tcctgaaaat tcaaataaaa aggattgtag
     2221 atgcctaaaa caaagatcgg caggtcctga ttatcctttc tggccaagtc aaggattttg
     2281 cgtaagcgct cttggtattg tcttgctggc tttttaaagt ttgacacctt aagattagcc
     2341 aagttcttgc gaataacagc caagacatca ttgccaccaa ccgtcaatgt catgagattg
     2401 gcttttttga gctgctctgt gatctcctta ttctcagtca ttctcgttaa aatttgctgg
     2461 ctggtattac cggaaacacc gtaattttca gtattaacgg tagcattaaa gtagtctcca
     2521 agatcaccag acaataaggg cacaaagcct ccttggttgg tgagatcacc cactccctct
     2581 gtcaaggagt ctccgatagc aatataatta aggcttatct tcttgttttt tagaaaatca
     2641 cttttcttca gctgtgggtc agactttgga ataaggacag ctaatatcac aaatgataag
     2701 gcaaaaacac tgaaaaagaa gataaggcct cccaaaaacc ctcgcttatt catatctaac
     2761 catcaccgca aaagcgccct cgccagtatg tgtttgaatg attgagccag tctccaaaac
     2821 agtaattggc ccatcaaaga cagtagcgat tgtctgcttc aggccatcag caaaatccct
     2881 ttgcccagca taggaaatgg ccacctcagc tatctgtcgc tgactgtttt ctgctaggta
     2941 gctatccagc catttggtaa aggttttatt gccgcgtcct ttaacaagtg tttgcagggt
     3001 atcatttttc atttccatga ccacacgaat gttcagcaag gagctaagca agcctgtcac
     3061 acgaccgatt cgtcccccct taaccaaatg ctcaagcgtt gacaccccta tgtaaagctc
     3121 tgtctttcgt ttaatactct ctactgcctc aaggatttcc tcaaggctag cgccagactg
     3181 agccagtcta gccgcctcaa ccacctgaaa cttcaaagcc tgatcagtaa agccagaatc
     3241 taataccgta acaggtgctg ctgcgatttc agctccctga cgtgatgcct caattgttcc
     3301 tgaaagagct ggtgagaggt gaatggcaac aatagctgtc gccccctcct tgaccaatcg
     3361 ctcataaata tctgcaaaaa gccctaccgg tggctgacta gtttttggca atgacttact
     3421 agctctcatc agctgtagaa attgcccttc ctcttttagc tcattatcag aatacagctt
     3481 gctatcaatc atgacagaaa gcggtacaac cgtaatatca agagatttga ttagctctgg
     3541 ttcaatcgtc attgatgaat ctgcaacaat tttaatagtt cccatcttaa attccattct
     3601 aacctcattt atcgtctctt tattttatca ctcctttaaa aataaagcaa agctggtatc
     3661 tagcccttgg tgttatctaa agcatctgtc aagaacttac cttcttaaaa gacaaaaagc
     3721 caagaccatc tcttagcttt tgttgttagc tactttaggc agcataaggc ctattagtaa
     3781 aagcagtaag ccagccagct gggcaggtag cactgttcga tcaccagtta gtggaagatc
     3841 gtatctgact tgatgtgctt taaagctgat cttacgatta aaaggaagca tacctttatg
     3901 accactaatg tcagaaatca cacgtcctaa ttcgtctaaa atagtggctg atgagtctaa
     3961 gccttttttg tgcttttgtt gcatgaccaa ttgctcagca agcttttttt cattttgagc
     4021 agccagcatt tctcccaacg aatgcccaac cacataatat tgaccagtca aatcagattt
     4081 tttagcaatc atggtcagca attggttcgt tgcagtatta aaggcctcaa gcttttgggt
     4141 caattgatgc ttggccatac tatacctctg cgctgcgttt gttctttgct tagcaacttt
     4201 cgatggatcc tcctttacag agaccataac ctcagataca tccacctgat cacctttaat
     4261 aaccaaatca ggaacagaat ccgctataat atctcgattg ctttcctcgt cagagctatc
     4321 aatggttaca ggatcgtcct cagctaaata aactgtcgaa gcctcttgct cgctcttgtt
     4381 ggcatctgcc tctttaggct ttaaagcttt cttctttagc tgatcagacg acgtgatgag
     4441 gccttcaagc acctcttgac tttccatgat ctggcttttc tcctcgttaa tctgcagcac
     4501 ctcagcctca gtatcagaat actgctcagc agtaactgaa cagcactgat aaataaaggt
     4561 tgttagcact agcaggcaag ctaagcccat tctttttttc agcattgtac ctccttaatc
     4621 tgcagttttt aatccttcta tttatcataa tattatcaat caatcactcg ccaatgcaag
     4681 agacaaaaag acttatcctc tgatagcata cgcataagag ctagccttct tgcttgcctt
     4741 tcaggtggct cattctgaac ctgtagcgat aagtgcagca ggcaagcttg ctctaagact
     4801 gctgttctgc ttttgctatg atactcagtc cttacctagc aattcacgcg cttgatttct
     4861 tgctgtctct gtgacatcag ctcctgcaat catctttgca atttcctcga tccgctcctc
     4921 ctgcgtcaac agcttagcct tagacactgt cgactcctcc ttgctttcct tggaaataaa
     4981 atactggtta tctgcaatag caatcacctg tggcaaatgc gaaatcgcta atacctgacc
     5041 atagcggcca attttatata tttttttagc aatggcctgt gccacacgtc ctgagacacc
     5101 tgtatccacc tcgtcaaaga caatacttgt cttgtcctct tttttagaaa tggcagcctt
     5161 gatagcaagc atcaagcggg aaagctcacc acctgaagca accttaacca gtggcttaaa
     5221 gccttcacct ggattggttg agatataaaa ttctaagctt tcattgcctt ctcggttaaa
     5281 ctttgacctt gtaaagtgaa ccttaaaatc agccttttcc atataaagct ctcttagctc
     5341 agctttgatg tcggcttcta attccaaggc cagggcgtga cgctgatcac ttagctgtga
     5401 ggcagtcagc accagctgct tctcaagagc ctttaattcc ctttccagct catcagatga
     5461 gcgatcacct ccgcttaata attggtattc cttggtaata ttggcatagt agtccaaaac
     5521 atcattcaca ccaccgccat attttcttgt caggctatta atgctgtcta aacgcagctc
     5581 aatgtcctgc aatctgcctg catcaaaatc aagctggtcg atggtatcag ataattgctt
     5641 tgtgacctcc tcaagaatat aataagcctc tgacacacca gctgatataa gctgatactc
     5701 tggggcaagg tcctcaatag acagcaactc attcatgcta gagcgaacct gtgagagact
     5761 ggaaaagtcc tcattatcca aggaaaggta ggcactggtt aaggtatcag caatcttttt
     5821 gtgattgagc aatcgctgcc tttcttgatt aagcaggtca tcttctcctc taaccaaatc
     5881 tgctgcatca atttccccta tctgaaaggc cagcaggtca aggcgcgcct gatgttcttt
     5941 ttcatttttt tgcttctcaa gagcctgcct tcgcaaagcc ttatagcgat caaaaatctg
     6001 ctgataggac tgcttgagct ggtcaaaggc ctcatctcca aaactatcca aaatatgctg
     6061 gtgcagctgt ggacgcatca attcctcctg atcatgctga ccatgaatat ccactaaaaa
     6121 ctgcccgagt ttttttaggg tgctgacagt gaccatttga ccattgatac ggctgacgct
     6181 acgaccgtta gcaaaaatat cacgacgaag aatcaactcc tcttccatgc taatccctga
     6241 ttctgccagc acagcggcta aatgaggatt agcatcaacc gaaaagaagc cctcaatctc
     6301 tgccttatca gcaccatgtc gaatcacctc agtgcttgcg cgcgcaccca gcagcatgtt
     6361 catcgcatca atgataatgg actttcctgc ccctgtctcc ccagtcagta cggtcatacc
     6421 gttttcaaag tttaaagaga tttcctctat gatagcaaaa ttcttaatgg aaatttctaa
     6481 taacattggc ttctttctat ttccttagac taatccctgc atccaaaggg acaattcctg
     6541 acggatatga tcagcgtctg cttctgattt tgcaatcaac agcaaactat catcatctgc
     6601 aatcaggcta aacaattgac ctgaaaagtc tgtcatcaaa taacgcttga ttagcttgct
     6661 attgccagga acaacgttga ggtgaatatg ctgctccaag cccgctgttt tttcagacat
     6721 ttccaaaatc gtttttttaa tagaggcagg cctttgcacc acccgcttgc cactatcctg
     6781 tgacaagcca taaatgtagc gacctgtccc agacggaatt ttgacaatgc caatttcatt
     6841 catgtctctt gagatagtgg cctgagttag ctctagccca taatcagcta ggagctttaa
     6901 tagctcatgc tgggtctcaa tctcatgaga caaaaccatt tttttaatta attctaatcg
     6961 ttcactcttt ttcatgctgt ttaaattcct tatgtgcact gctaacaacg ctctgtatga
     7021 gctgatcatc aatagccttg gagctgtttt ccttgactaa atgagctaaa aattcaatat
     7081 taccatgacc accttggata ggcgaaaaat caagcccctt aactataaat ccgcaattaa
     7141 gagcagtatc tgttacctgc ttaatcactt tttcatgaat cagccgatcc ttgacaattc
     7201 cttttttgcc aatctgctcg cgccctgcct caaactgtgg cttaatcaga gcaacagcct
     7261 ctgctccctc ctgtaaaaga ctgcacaaag ctggcagtat caggctaaga gaaataaaag
     7321 acacatcaat gctggcaaag gctggctgac cttctgaaaa atctgccagc tttgcatagc
     7381 gaaaattgta ctgctccatg cttcgaacac gactatcctg cctgagcttc cagaccaatt
     7441 gattggttcc aacatcaaca gcgtaaacca gcctagctcc tgcctgtagc ataacatctg
     7501 taaagccacc tgttgaagca ccaatatcaa ttgtcacctt atcctgcaca gagatcccaa
     7561 agacctgcaa ggctttttcc agcttgagac cccctcggct gacatactta agcttctcac
     7621 ccttgagcct tagttcgatc ccctcatcaa tcttttcacc aggcttatca aagcgtaagc
     7681 cacttatagc tgatatgact agtccagcca tcacaccgcg cttggcctgt tctcgcgttt
     7741 caaaaagtcc ctgtctatag gctagcacat ctactctttc tttagccatt tagtcgcaac
     7801 ccctcgatcc ttttgataat agcctgagac tcaaagcctt cttccctttc tagcctgcta
     7861 aaaatagcta gcgcttgact caaagactcc tccaaaatag cccttgaacg ctctaaacca
     7921 agtagactcg gataggttga tttttcaacg gcaagatcct tttgcggtgt cttgccaagc
     7981 tcatcaaagc tagcagtaac gtccaaaata tcatctctta tctgaaaggc ctgtccaaca
     8041 agcctaccag cctcccacag acaagacaaa acgtctgctg actgctcagc tatgataccc
     8101 gcagccacaa aaggaagggt caacaatttc cctgttttat tggcatgaat atcagatagc
     8161 tcctgaatat ccagcagctg ctgctcaccc ttcatgtcca agagctgacc accgaccatg
     8221 ccaaaggttc ctgacgctaa ggaaaactgc tgaaccaatt gcaccagcag gtcagccggc
     8281 aaatctgccc ctgcgattag agcaaaaggg tccaaaaaaa gactatctcc tgccaaaata
     8341 gcagttgctt catcaaattg cttgtggcta gttagtcgcc cgcgacggta atcatcgtta
     8401 tccatagcag gcaaatcatc gtgaatcaga cttcctgtat gaatcatctc aatagcagca
     8461 gcaaccgcgt aatgggcgtc tgtcaaggca agaccaaagc cctctagcag ctccaataaa
     8521 atgagtggac ggagcctctt tccaccgcca tcaacagaat ataaaatggc ctcctccaga
     8581 tctgctgaaa cagtagactg cctgtcataa tgctgatgaa tcgtggcatt aattcttgtt
     8641 agcttatcca ttaggcgtcc atttctagct ctgtgccatc tgcctgcatg accttaacaa
     8701 gtgtcttttc agctgcttgt aaggtttttt gaaggtcctt ggacagcacc ataccctttt
     8761 gaaattcaga gatggcttct tctagtggca catcaccatt ttctagcctt gtcacaatgg
     8821 cctctaattc ttgtaaacgt tcttcaaatg tttttttcgt tgacatcttc tacctctact
     8881 tctaattgac catcacgcat gacaatgcta agatgatctc cctttttaat gtccttaaca
     8941 caggcagcta ctgcaccgtc cttttttaac aaggcatagc cgcgggcaat gatacgactc
     9001 gtatcaagcg acagcagggc agcttgagct cgttcaaagc ctgctagctt actgtcatat
     9061 tgattggtca tattggctat caagagacga tgtgcagttg ccagacgatc ctgataacgc
     9121 tcaagccttg cttgtacgtt gacagaagct aagcgatgct ccaaaatcag atgctcttgc
     9181 ttagcttctg ataatgtctc cttaaaggta gtcatcaagg aggtcgtaag cctatctagg
     9241 cgttggctat aagcatcata gagcctctct ggctgcctga acataacaga ataagacagc
     9301 ttatccactc gctcctgccc ttgtctgata tagcgcaaac aggcctgata ggaacgattc
     9361 tgttgctcag caatccaaga aacaatatct gtttttgtaa taggtgtcac tagctcagca
     9421 gctgcggttg gggtagcagc tctgcgatca gccacaaaat cagccaaggt cgtatctgtc
     9481 tcatgcccca cactagaaat aacaggcaag cgagactcaa aaatagcctg aacaacgatt
     9541 tcctcattga aagcccacag gtcctcaatc gagccaccgc cgcgcccaac aatcaacaaa
     9601 tccagatcct cacgctggtt agccctagca atattagcag caacctcttg agctgccccc
     9661 tcgccctgaa cctttgttgg aaacaaaaga atgctcaccc caggaaaacg ccttgaaatg
     9721 gttgtgataa tatcacgaat cacagcccca cttggactcg tcacaacacc tacctttgtc
     9781 acaaattgtg gcagagcctg cttatgcctc tcatcaaaga agccttcacc agccagcttt
     9841 tgcctgagct gctcaaattg cagcgccaaa gcaccaatac catctggctc agccttttca
     9901 atgatgatgg aatacgagcc gtttggttca tagagctgaa tacgcccgac cacattgagc
     9961 ttcatgcctt cttctaaatc aaagccaagc tttttataag ctcctgccca catggtggcc
    10021 tgaatcaccg ccccctcgtc ctttaaggaa aaatattggt gatttggtct ttttctgaaa
    10081 ttggacacct gaccagtgag atagacacgc tccagataag ggtctcgatc aaatttcaat
    10141 tttaaatatt ttgtcagctg agtgacggat aaatagtctg ccatcagttt acctttcact
    10201 tcatgaagcc taactgctcc aactgtatac taatgcaatt atatcatgtt tccacataaa
    10261 tagtgagcaa aaaagagaca aaaaaagaag ccagctaagg cttctacagc ttgacacaag
    10321 tttttccaat gatagcttcc ttgaatcata aagcagcacc cagtcttaag ctagcagctc
    10381 taaactcaaa atagctaaac gactgaaacc agctgctgtc atgcctacca attaaccgct
    10441 ttttccaaac gacctcgcag cacagcctca acctagcttc tggcctgtgc tgattgcctt
    10501 tagccatcta ggaagctcat agctaatagc agtcggcaaa accacatagg cagtctttgc
    10561 cagctcatca gcaatggcag agtgcagata ggtcgcacaa gcaaccttat ccaccaagct
    10621 tgactctgga aactggacag ctatccctgc tatcatacct gccaaggtat ctcccatacc
    10681 acctgtagcc tgatagggtc cgcccactct tagccggtag atctggttgc catgataaat
    10741 cttggttgct gagcttttag caaccaaaat cgtagccctt gaaaaacgcc tgagagctgc
    10801 ttggttggca gcatcatgct gctgatcaat cgctaaacct gacagcgcct cccattcctt
    10861 ttggtgcggc gttaacacaa gagggcacct cagctgcttg gtatcagctg tctttttcgc
    10921 taaaagcctt aaggcagagc catcaatgac caatacctgg tggtcagcga catgtgcaag
    10981 gaccagttca aacagcctag ctgctctgct attctccgac agccccggac caatcaaaat
    11041 caggtctgcc atacctagct gagataacag taattcctca tcatctaccg caatcgccat
    11101 cgcctctggc aaatgactat gcaaggcagc aatattctcc ctatccgtag caacagtcac
    11161 cagacctgct ccactatgaa cgcaagccag cgctgccata ataatagcac caccgtatgg
    11221 atacaagccc cccaccaaca gcactctacc atagctgccc ttatgcgact cagtctgccg
    11281 cggaacaaca accctagcaa caagcgattg atctataatc attgactcac ccttcttaga
    11341 gctgcttgat aggtttgctc caaaagcata gtaatggtca tcggtccaac accacccgga
    11401 acaggagtaa tcatgctagc catctctgac acctcatcaa aggcgacgtc tccaatcaat
    11461 cgcccattga cgtcacgatt cataccaaca tctataacaa cagcaccctc tttaacaaac
    11521 tcctttgtga taaaatgccc ctgaccaata gcaacaatca agatatcagc acgacgacaa
    11581 atatctgcca gtcggcgcgt gcgcgaatgg gtaagcgtta ccgtagcatt tttatccaac
    11641 agcagctgcg ccataggctt cccaacaata tttgagcgcc cgacaataac agcatttttc
    11701 ccttcaagtt cgataccata gtcatgaaac atctccataa tccctgccgg agtacaaggg
    11761 accatattcg gacgacctga ccacagatga cctgtattca tagggtgaaa gccatcgacg
    11821 tcctttttag gatcaatagc aaggataatg cttttgtcat taatatggtg cggaagagga
    11881 agctgcacta aaataccatg aatcgtatca tcttgattat attgctcaat gagctctatc
    11941 aactcttcct gacagactga atcagacaag cgaacggttt cacttttaaa acctgctgct
    12001 aaggcagcgc gttccttatt acggacataa acctgactag cagggttgtc tcctaccaga
    12061 atgaccacaa ggcctggaac aattcctttt tctgccttta agctctctac cttcttagcc
    12121 aatgctgcct gcattttctg tgctagggcc ttcccatcaa taatctgtac catatgcact
    12181 ccttgctaat tttttaacta ttataacgaa aaaaggaagc actgtcactt ccttttcctt
    12241 tttgcttatt gattagctga ttttctgttg cagagcttga acaattagct gacactgtcc
    12301 atctttgctt gacaggctga ctcaatagcg tctagcttag caatgctgtc tgcctctgtt
    12361 tcaccaatag tatagatgta aagcttgatc ttaggctctg ttccagatgg tctcagcgca
    12421 taccatgacc catcatcaaa ataatatttc aaacaatttt gctttggaaa atcaaggtag
    12481 ccgtccttaa agtccacaac ggtctttaag ctcatagcac ctgcacgctc aataagctta
    12541 tttctaaagt cctccatgat acgtgcaata cgcttttgcc cctcaacacc ctctaattca
    12601 agcgctacct gacgctcatt gtaataacca aattccttgt aaatatcttg aagcacgtcc
    12661 aagagtgact gacctctttg cttgtagtag gcagccatct ctaccaccat cattgaggca
    12721 ctaaccgcgt ccttatcacg cacaaaagta ccgtaacaaa aaccaatgct ttcctcatag
    12781 ccaaagacat aggtcttctc ctttgtgatg tcataatcat tagccttgcc acagatgttt
    12841 ttaaagcctg taagggtctc aaccgtttca atgccatatt tagcggcaat agcctttgac
    12901 aaatcccctg tcacaatgga tttgacaagg acaggattgt caggaaggtt atgcctagca
    12961 tggcgctgtg aaaagatata gtaggacaac aaagcaccaa tcttattacc attaagaaag
    13021 acataactac cgtcagcagc tcgaacctct agtgccacac gatcacagtc cggatcagtc
    13081 gcaatcagaa tatctgctcc tacctcttgc cctagtcttt ctgaataagc aaaggccttt
    13141 ggcacctctg gatttggata accaactgtt gtgaaatctg ggtctggcat ttcctgctcc
    13201 ggcaccacaa agacatgatc aaagcctcgt ctcttcaata cctcacgaac aggtaaatta
    13261 ccaacgccat tcaaaggtgt ataaaccaca cgcactgact tatcaatatc agtatcattg
    13321 atggtcaagc ctaaaacctc tttcttatag gcctcctcta tactatcatc aatatagctg
    13381 gtcagaccac ttgccaatgc ctcctcaaag ggtatctgct taacgtcctc aaagcgctca
    13441 atagcgtcca tatgagccgc tatctgatta gcaatgtcat ctaggatctg tgagccctct
    13501 tcccaataag ccttgtagcc attgtaggcc tgaggattgt gactagcagt aatcataaca
    13561 ccagagatac aattcaaggc acgaatggca taagagcaca ttggtgtcgg acgaataccc
    13621 ttgtagatat aagacttgat cccattagct gccatgatag agcaggtcaa ttctgcgaac
    13681 tctttagact tgtagcgcac atcatagctg atggcaatcc cgcgtgagac tgcttctggt
    13741 ccatgatcaa taatggtatt agctaaagcc tgagcagcct taccaaccat ataaatattc
    13801 atgcggttgg taccggcacc gagcttgcct cgaagcccag ccgtcccaaa ctcaagcacc
    13861 ttgtaaaaac gatcttgaat ctcagcctca tcatgcttaa tcgcctctaa atctgccttg
    13921 atttcttcat tgaaaaaatc attgtgcagc cactcctgat aaacagcttt gtagtccata
    13981 ttatcctcct actttcagac caccatgttg atatcaacat gttacttaag atgtcatcat
    14041 atgataatga ttgccatcat caaaaaagca aagcgctttc taatgacaga cttacctgaa
    14101 tagtaacaaa caataacaca aaagtcaacc taattccgca attaagcaat gttaacacac
    14161 acgcaaatga aaccccttac tcagcacaac aagcaaagcc cttgtgacag cctgccacaa
    14221 cagtgctgac aaataaagag accacacctt caatcactag ggataagccc tcagcgctca
    14281 gcgagtagat ccagacctgc aaagccagat atggctacag cactagccaa actttctaat
    14341 ccttttacag aaaaaacggc caaagcaaac aggccacagc aagagttaac tgactaatag
    14401 ccagcccttg aggtgacatg ctccccctta gctgccctag ctatgacaat accttactca
    14461 aaaagtcctt ggttcgctcc tccctagggg cttcaaagac ctgatcaggg ctgccttctt
    14521 caatcacaag gccaccgtcc ataaaaatca cacgatctgc cacctctttg gcaaagccca
    14581 tttcatgcgt cacaatgacc atcgtcatgc ctgattttgc caaatcctgc ataacagcca
    14641 aaacctcacc caccatttcg gggtcaagcg ctgaggtcgg ctcatcaaag agcagcacat
    14701 cgggatccat tgccaagccg cgcgcaatcg caatgcgctg ctgctgacca ccggataagc
    14761 ttgccggata ggcagcagcc ttatctctca gcccaactcg ctcaagcagc tcataagctc
    14821 tctgctccgc gccagccctt gacattcctt ttgttttgat gggtgacagg gtgatgtttt
    14881 ccagcactgt catattggga aacagattaa actgctgaaa aaccatgccc atcttctcac
    14941 gcatcttgaa aatatcattt gccttatccg taatatcgac gccctcaaag ctgatgtgtc
    15001 cctttgttgg cacctcaagc aaattcatcg tgcgcaatag cgtggacttt cctgagccag
    15061 atggcccaat aatcaccaca acctcaccct gattaatggt caggtctatt ccttttagca
    15121 cctcatgctg cccaaagctc ttatgcaact gacgaatcga aatcactgtc tcagtcatct
    15181 tatctccctc cctgtgctag cttgcgctcc aagcagccta ataattgcga caatattgtt
    15241 gttatcatca agtaataaaa ggccgcaaac agcaagggtg taataggcag ataggtcgcc
    15301 gtcacaaccg actgagctcc attccaaagc tccatcacac caatcgtctg aagcaaggca
    15361 ctatccttga taatggtgat caattcattg cccaaggccg gcaaaatatt cttaaaggcc
    15421 tgaggcaaaa tcacatagcg catggcgttc ttaggacgga taccaagaga gtaagcagcc
    15481 tccagctgcc cctttggcac cgcctcaatc ccagccctga cgatttcaga tatgtaagca
    15541 ccgctattca aggaaataat aataatacca ggaagcagtc ttgaaaaatc caaatccagc
    15601 accccaaagc cgatcgtcgg caggtgatta aaatgcagcc aagcaaaggc aatcataatc
    15661 tgcaccacca tcggtgtccc acgaaagacc cagacataaa gactgaccag ccaggataaa
    15721 ggcttgatat gactgcgttt tatcagtgtc accagcacac ctatagccgt tccaaaaagc
    15781 acaacacaag ccgaaatcat cagggtaaca agcaccccat agttgaaata agcccaatat
    15841 ttaggcaaaa aagtaaaatc cattccaatc tcctaatctt gatagcatga ttacaataga
    15901 gataattata ccacttgatg aatattaata caacatcttt tttcaataat cctctctcac
    15961 agctcaataa gcctaggctc aagacaaaga ctacaaagcc agaaggcttc ttagcctaca
    16021 ggtgaacgcc tgagctcctt tactatcctg caatgagccg gtcacagcac ctctgcagct
    16081 aatagctagc aactgataaa gtcagacgat aatcattttc attaaaaaaa aaaaaaacga
    16141 atctacggag aaaaactgac tagcagctat ttctcaccag cggctgccat gctaaactct
    16201 tctttgggaa agaatttaaa ataatgataa tatcatcaaa ggagagaaag atgagaaaac
    16261 caatacgcaa gtacagcgtc tgctcagcag ccattgctct agcaacaatg gccagcctag
    16321 gaacagctgg aaatgcccga gctgaacata aagaattaaa ggactatcca gacccaactc
    16381 gtagaattag tagcaaaaca ctgggagata atgaagtaag aaaatatctt catgaattga
    16441 gagactttct aaagggttac ctaaaagaat tagaagaaaa agcagaacaa cctggaccta
    16501 tggggcctgc cggacccgcg ggacctattg gccctaaagg agaagctggt cctcaaggtg
    16561 agcctggacc tcaaggtgag cctggacctc aaggaccgcg tggagataaa ggtgaaaccg
    16621 gagaagccgg ccctaaaggc gaacaaggac ctgctggaaa accaggagaa gctggtccaa
    16681 agggtgaacc gggtgagcga ggtcctaaag gggacaaagg cgacactgga gctacaggac
    16741 ctaagggaga cagaggcgaa cgcggtgaaa aaggtgaaaa aggccaacgc ggtgaaaaag
    16801 gtgaaaaagg ccaacgtggt gaaaaaggtg agcaaggcca acgcggcgaa aaaggcgagc
    16861 aaggccaacg cggcgaaaaa ggtgagcaag gccaacgtgg cgaaaaa
//
LOCUS       DARYSY010000047        16245 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYSY010000047 DARYSY010000000
VERSION     DARYSY010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16245
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            374..1996
                     /gene="nikA"
                     /locus_tag="TVR04_001487"
     CDS             374..1996
                     /gene="nikA"
                     /locus_tag="TVR04_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1270164.1"
                     /translation="MKTKLNVLLLFLFALLLTACQNAKQASHRTDQLRIAWGEDFGDV
                     NPHRYNPDQFIIQDMVYEGLVRYGDKGKIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDTIFSEQNKGNHNWFHFTNQLESYRALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHEGYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQLLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSALVEPDEDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKNAADKAVKN"
     gene            2074..3015
                     /locus_tag="TVR04_001488"
     CDS             2074..3015
                     /locus_tag="TVR04_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270165.1"
                     /translation="MIKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGPSSLVLPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLMRNALPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKAKEEACPNT"
     gene            3000..3806
                     /locus_tag="TVR04_001489"
     CDS             3000..3806
                     /locus_tag="TVR04_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270166.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGARYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            3794..4582
                     /locus_tag="TVR04_001490"
     CDS             3794..4582
                     /locus_tag="TVR04_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270167.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPANVQMTGSITCQGMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQMIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGEL
                     LVMSKGKVIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            4569..5249
                     /locus_tag="TVR04_001491"
     CDS             4569..5249
                     /locus_tag="TVR04_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270168.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQAYQLTYIFIAHNANICQAICDRVLLLEQGRLVAVRDKESQTS
                     CGDIELDN"
     gene            5939..6667
                     /locus_tag="TVR04_001492"
     CDS             5939..6667
                     /locus_tag="TVR04_001492"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1270169.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGIGINITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKVCD"
     gene            6704..7261
                     /gene="frr"
                     /locus_tag="TVR04_001493"
     CDS             6704..7261
                     /gene="frr"
                     /locus_tag="TVR04_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1270170.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            7395..8252
                     /locus_tag="TVR04_001494"
     CDS             7395..8252
                     /locus_tag="TVR04_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1270171.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHSLGDM
                     VKGFVYTDMKHRLRLTTKPIDSRRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLANPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            8590..9099
                     /gene="msrA"
                     /locus_tag="TVR04_001495"
     CDS             8590..9099
                     /gene="msrA"
                     /locus_tag="TVR04_001495"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1270172.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVPNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAEQSKQSLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPQRYAQSSAIR
                     HQFLEEHWQ"
     gene            9096..9311
                     /locus_tag="TVR04_001496"
     CDS             9096..9311
                     /locus_tag="TVR04_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1270173.1"
                     /translation="MRKAFYTWLMAQRHSTSNKPAALLADLVFEDTTFPKHTDDFETI
                     SRYLEEEANFAFNLGQFDQIWEDYLSH"
     gene            9414..10514
                     /locus_tag="TVR04_001497"
     CDS             9414..10514
                     /locus_tag="TVR04_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1270174.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTIRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDTSQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVYFSAKDVVRHPVVAEIIKAYETVGSKVESLKSSPNQLQHQA
                     KAPDRPKTETGQSTSGLTTYEIIGELPKEDKS"
     gene            10561..11136
                     /locus_tag="TVR04_001498"
     CDS             10561..11136
                     /locus_tag="TVR04_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1270175.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPHVKLVVLVGQYAQQYYLGKGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELIPVLKDKVRQILRD"
     gene            11191..11817
                     /locus_tag="TVR04_001499"
     CDS             11191..11817
                     /locus_tag="TVR04_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1270176.1"
                     /translation="MASFFEKLAEHSYLETERLCLRPVTLDDANAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKATGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKDNPASGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDQQKSLASANKPDRYLNNSFKNS"
     gene            12158..12655
                     /gene="ybeY"
                     /locus_tag="TVR04_001500"
     CDS             12158..12655
                     /gene="ybeY"
                     /locus_tag="TVR04_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1270177.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            12636..13037
                     /locus_tag="TVR04_001501"
     CDS             12636..13037
                     /locus_tag="TVR04_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1270178.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            13175..14071
                     /gene="era"
                     /locus_tag="TVR04_001502"
     CDS             13175..14071
                     /gene="era"
                     /locus_tag="TVR04_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1270179.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNKKEY"
     gene            15106..15240
                     /locus_tag="TVR04_001503"
     CDS             15106..15240
                     /locus_tag="TVR04_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEL1270180.1"
                     /translation="MADEVLKLQMLSVEEETDEVDGMRFSTTSLSWCGNWSAISAFGC
                     "
     gene            15351..>16245
                     /locus_tag="TVR04_001504"
     CDS             15351..>16245
                     /locus_tag="TVR04_001504"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1270181.1"
                     /translation="MVRLIYYQFNYRRREWSGAFPVLFSAGVVVGTCFTILFNVLGNT
                     ELFSRVIPAPLFIAPVFFGGLTLFFLISTLIKLLLNIFKDEYRLWYILGADRRQLSML
                     VGGQFAIVTLISSFIGSFISILSAKSYYYLIQGRVGVDYFPSISIQFNLLAVFLTIIF
                     LTLVCFASATYNAYKLLDENIIFEEDKGEKKIYKFTKFGIFGINVFLWLSLVVGSVVV
                     PYLDLPGGVSYKLSFMSSAIFYLLVIHILFLKYLSPWIELRIVQFLFKKVKGFATVLS
                     KWSVIEKKYFLSSVTISMVTAI"
BASE COUNT         4407 a         2874 c         3922 g         5042 t
ORIGIN      
        1 attaacacct aaattgtctg atattacaac taattgctaa ggaccttaaa ggaaattgat
       61 gctatcagga ttgtttatct tgatagctga tcagtaaggt taacgttcgt cttttatcat
      121 tattttggct tcctttatca ggtaattgtt cattatttct aataactatt agaaaatatt
      181 cctcagcaag cttgaagtgt tcatgatttt gacgttctcc ttatttgtag ccttctggct
      241 ttttctaggc tggttttgtc tcattttttc ttgacaagag ggccataaaa tgattaaatt
      301 aaccatactt aattttgtga taaaccacat ctaaaattag atagattcat atctttagaa
      361 agttaatgac ataatgaaaa ctaaattgaa tgtgctattg ttattccttt ttgctttgct
      421 gctgacggcc tgtcaaaatg ctaagcaggc gtctcatcgt acggatcagc tgaggattgc
      481 ttggggtgag gattttggtg atgtcaatcc tcatcgctac aatcctgatc aatttattat
      541 tcaggacatg gtttatgagg gtttggttcg atacggtgat aaggggaaaa ttgagccagc
      601 gttagcagag agctggacga ttagcccaga tggcaaaacc tataccttta acctgagaca
      661 ggctaaattt tcagacggct ctgattttaa tgctcaaaat gtcaaacgga attttgatac
      721 gattttctct gagcagaata aggggaatca taactggttt cattttacta accaattgga
      781 gagctacagg gccttagatg accatacttt tgagattaag ctaaaggagg cttatagtgc
      841 gactctttat gatttgtcaa tgattagacc gattaggttt ttagctgatg ctggttttcc
      901 tgatggcgat gacaccaata agcataatgt taaaaagccg attggtacag gtcaatgggt
      961 tgttaaagag aaaaaggcaa atgagtacat tacctttaca cgtcatgagg gctattgggg
     1021 agaaaagcca aagctaaagg aagtaaccat caagattatg cctgatgccg agacaagagc
     1081 cttggcgttt gaggctggtg atattgattt gatctatgga aatggtctga ttagtcttga
     1141 tacctttgtg caatatgcta aggacaagaa gtatgttact gatgtttctc agcccatgtc
     1201 gactcgttta ttgctgttaa atgctaagca gtcagtgttt caggacaagc gggttcgtca
     1261 ggcaatgaac catgcggttg acaaaaaggc tattgctaag cacaccttta gaggaacaga
     1321 gacagcagca gataccattt tttcaaaaac aacaccgcat gcagatgcag gcttagttcc
     1381 ttatgaatac aatctccaaa aggctaagga tatgttgaca gccgctggct ggaaggaaaa
     1441 ccaagagggg attagggaaa aagatggtca gctcttgcgt ttacaggtgc cttatatttc
     1501 aactaaagca acagacaagg atttggttga atattttcaa ggcgagtgga aaaagcttgg
     1561 gattgatgtg gtcttgacag ctatggagga ggatgactac tgggctaatg ccaagacagg
     1621 acagtttgat atgatgctga cctattcatg gggagctcct tgggatcccc atgcttggat
     1681 gacagcctta acggcaaagg cagatcatgg gcacccagaa aatattgcct tagagagttt
     1741 gccatcaaag gctgagattg atcgcctgat taaatctgct ttggttgagc cggatgagga
     1801 taaggtagac aagggctata agcaggtatt gtcactgttg catgatgagg ctgtttatat
     1861 tccactcacc tatcagtcag ttgtttcggt atatcgcaag ggagacttta agacaatgcg
     1921 ctttgcacca gaggaaaatg cccttccttt acgctatatt gaaaaaaatg ctgctgataa
     1981 ggcagtcaag aattgataga gcagaggagc tggttgtgag tgactatcct gacaactctt
     2041 atctgatgtc ttagtgaagg gttgagagaa aatatgataa agaagcttat ttctaccttt
     2101 ggcgccttgc taatgatttc gatagtgacc tttgttttgg ttaagctatc ctccgctaac
     2161 ccggcagagc agtatttgcg cctatctaag atcagtatta caccagaagc tcttcacaat
     2221 gctaggctct atttgggctt agacaagcct ttatgggagc agtatgtgac ctggttatct
     2281 gacattcttg taggaaattt tgggacctct tacgtgttaa aggtccctgt cctgcctttg
     2341 gtggtggagc gctttttagc aacgctaatg ttaagcttga cctctttttt actggtactt
     2401 gtgattgcct ttcctttggg ggtaggcagt ggtttgtttg agcattcctt gtttgatcgg
     2461 ctggtgcgtt tattcagctt tgtggctgtg tcaatgccta gcttttggtt gggttatctc
     2521 ttgattatag ccttttctgt taagctaaat ctcctgcctg tgtcaggcaa ggcaggtccc
     2581 agcagcctcg ttttgccgag tattacgctt agcttttcct tgattgggca atatactgct
     2641 ttgatacgaa aggcaatcag tgagcagcta acgagtctgc atgttgaaaa tgccaggcta
     2701 agaggggtta agacctatta tattgttaag catcacctga tgagaaatgc ccttcctgct
     2761 attgccacag gcttgagctt gacctttgtt tatttgatga cgggctctat tattgttgag
     2821 gatattttct catggaatgg tattggcagt ctatttgtta tgagtctgaa ggcagcagat
     2881 attccggtta ttcaggcctg tatgctctta tttggtgctt tgtttttact acaccatgtg
     2941 ataactcaag agctagtgtc ttttattgac cctcgtctgc gcaaggcaaa ggaggaagca
     3001 tgcccaaata cgtaattggt tcagctgtta tgctattgct gttgtttatc tgtgtcttgt
     3061 ttgctcctta tcttgctccc tttgatcctc atgctgttga tgttgctagt aagctcatgc
     3121 cacctagtca gcagcactta ttaggaactg accaattggg aagagatgtg ctgtcgcgct
     3181 tgttatatgg ggctaggtat tccttgcttt tggcggttac tattagtttg ttagagctat
     3241 ctattggtgc tgtggttggt ttggttgtag gctggtatca aggaaggctc gaggcagctt
     3301 ttctgtggct agctgatgtt gtttctgcct ttcctagctt tttactatcg ctagctacaa
     3361 tggggatact tgggcagggc ataggcaaca tgatcctagc tattgttctg gtagagtggc
     3421 tgtattatgc taggctgatg gtcacgatgg tcaaaagcgc taaggcagag ccatatgtca
     3481 ttagtgcgca gacaatgggc ttatctgtgc ggcatatctt aaaaaagcat atcctgccat
     3541 ttgtttatcg gccgattgta gtgttggctt tgatgaatat tggcaatatt attctcatga
     3601 tctcaagctt ttcttttttg ggtatcggtg ttcagcccaa tgtgacagag tggggaatga
     3661 tgttacatga tgctaggagt tattttagga cagctctgtg gctgatgatg tcaccagggc
     3721 ttgccatttt agtgactgtg ctagctttta acagcctagg tgattacgct gatgctaagg
     3781 ggtggaggaa aacatggaac ggttaattgt taatgattta tcggcttata atggctctga
     3841 tgtgctatta agtaagctca atcttgagtt gcccttgggg agctccttgg tgattgttgg
     3901 caggagtggt tcgggcaaga ccctcttgac taagctatta attggtcaat gtccagcaaa
     3961 tgtgcagatg acagggagca ttacctgtca gggcatgaga ctagatcaat tagacgccaa
     4021 gcaatggcag agcattagag ggcgccacat ggcctatatg gtccaaaatc ctatggcaat
     4081 gttcaatccc tttcagacca ttgaggctca tctccttgaa accatccgaa gtcatgagag
     4141 actttcaaaa agagcctgtc taaaaagggc tctgcctttc atgcgagagc tctatctaga
     4201 gcagccagag gagctgctga ggaagtaccc ctttgagcta agtggtggta tgctacagcg
     4261 ggtaatgcta gctattttgc tgtgcttaga cccacaaatg atcattttag atgagcctac
     4321 ctctgcttta gatgatgcca atcgttctaa tatcatacgg atgctgaagt tattgcagga
     4381 caagggaaaa accattatta cagtgacgca tgattaccaa ttggcacaga ccttgggagg
     4441 ggagctgctg gtgatgagta agggaaaagt catcgaacaa ggaagtgttg agtcgatttt
     4501 tcatcggcca agtcaggctg ccaccaagga gttgcttttg caaaatcatt atgatcggct
     4561 gatacgctat gatagagttt agacatgttt ataagagctt tcatcaaaag ccagtgctaa
     4621 cagattgtca ttttcaaatg gaaaagggtg agagccttgg gattatggga gaaagtggta
     4681 gtggcaagac aacgcttgct aggttaatca ttgggctaga gcagccgaca gctggtcagg
     4741 tgctctttca tggtcagccc tattctgtaa aagtatgtgg acctcggatt ttacttgtct
     4801 ttcaggatgc gctaagatca gtcaatcccc tctttactat tcaagagata ttgacagagg
     4861 ccctttctaa ggactttgcc ttagaggagg ttgttcaaat actagctgcg gtcggtcttg
     4921 acgccactca tctgggtaaa aaggccagag agctgagtgg tggtcagcta cagcgtgttt
     4981 gtatagcgag agctcttttg ttaaggccgg aggtgatcat ttttgatgag gctttgagtg
     5041 gcttggaccc tattacccaa gggcagctat tggacttgct ctatgagtta aagcaggcct
     5101 atcagctgac ttatattttt attgcccata atgctaacat ttgtcaggct atttgtgatc
     5161 gtgtcctgct gctggagcag ggcaggctag tagctgtcag agataaggaa tctcagactt
     5221 cttgtggcga catcgagcta gataattaaa ataaatcatc tctcaatatc acatgacttg
     5281 gaatccggcc tggcttgagg ctagatttta agtctttttt tgttgctgtt ttgttttggt
     5341 atgatctgtc taccctgctg tacatgaggt aaggagctta tgctaaggtg tgagaacctt
     5401 gtctgtgttt tgggtgatgt gcttatggtt aacctagcag ctatgagaga tttaggctac
     5461 tgataagcct tcgcggtttc atcaatgctt ttttagcggc ccaagtgagc taggagctag
     5521 actttttgtt gtgctgcgcc ttgctgacct gttgagcttt agctcttaga ggctttgaga
     5581 cctgctgagt atgacatgtc aaaggaggct ggtgtccttc ctggcgtttt aagaaaatct
     5641 tgttttaaaa gatatggtgc caattcctga ggctgatata aagcttagct gataagtata
     5701 aaaacgaact ataaatacat ttttgtaata tttattctgt ttttagtcgt gttttgggtt
     5761 atagctgtac tatttggata ttataatacc ttttttgtaa caattcatct tttttgctgc
     5821 tcttggaggc tttgacaaaa ggatcatcaa aaatttcgct ttcctctctt gcattggtct
     5881 attaaatttt tttgttttgt ggtagaatgg taaggacaaa ataaggagat cataaatagt
     5941 gaaacctaaa tatcaacgta ttttaattaa attgtctggc gaggccttgg ctggtgataa
     6001 gggtataggc attaacataa caacggttca gtcgattgct aaagagatcg cagaagtcca
     6061 caattcaggt gttgaaattg ctcttgttat tgggggtggt aatctctggc gcggcgagcc
     6121 tgctgcagag gctggtatgg atcgtgtgca ggctgattac acaggcatgc ttggaaccgt
     6181 tatgaatgct ctagtaatgg ctgatagcct tcagcattat ggcgttgata ctcgtgttca
     6241 gacagctatt cccatgcaaa acgttgcaga gccttatatt cgaggtcgtg cgcttcgtca
     6301 tctggaaaag gggcgcattg ttgttttcgg tgctggtatt gggtcacctt atttttcaac
     6361 agatacgaca gcggccttac gtgctgctga gattgaggca gatgctatct tgatggctaa
     6421 aaatggtgtt gatggtgtct acaatgctga cccaagaaag gacgcaaacg ctgttaagtt
     6481 tgatgaattg actcatgggg aggttatcaa gcgcggtctc aagattatgg acgcgacagc
     6541 ttcaaccttg tcaatggata atgatattga tttggttgtc tttaatatga atgaagcagg
     6601 aaatatcaag cgtgtggtct ttggagagca tattggcaca acggtatcaa ataaggtctg
     6661 cgattaggat tttagagcta aaggattaag gagaaaaata atcatggcaa atgcaattat
     6721 tgaaactgcg aaagaacgtt ttacacagtc acatcactca ctagcacgcg agtatgcaag
     6781 cattcgtgca ggtcgtgcta atgctagcct tttggaccgt attcaggtcg attattatgg
     6841 tgcaccgaca ccattgaacc aattggcttc tattacagta ccagaagcgc gtgtgctttt
     6901 gatttcacca tttgacaaat catctatcaa ggatattgag cgtgccttga atgcttctga
     6961 tttgggcatt acaccggcta acgatggctc tgtcattcgc ttggttattc cagcgcttac
     7021 agaagaaaca cgtaaggaat tagctaagga agtgaaaaag gttggtgaga ctgcgaaggt
     7081 ttcgattcgc aatattcgtc gtgatgctat ggacgaggct aaaaagcagg aaaaggctaa
     7141 ggaaatcacc gaagatgagt taaaagcctt ggaaaaggat attcaaaaag caacagatga
     7201 ggctgtcaaa gagattgatc gaatgactgc tgacaaagaa aaggaattgc tttcagttta
     7261 agtggcttat ctgaccatta agctagatca gctgcgtaac ctaatacaca tcaggcataa
     7321 aaggataggt gacaaggcta aaaagcagct gctttggact tgtccctatt ttttaaagga
     7381 aagaataaaa agaaatgaac catttattag caacagtcat cactggctta gtaaaagaag
     7441 aaaatagtca gttttatctt gtccaaaagg aggggctgag ctttgctcta gctaaggagg
     7501 aaggcagcca tagcttagga gatatggtta agggctttgt ctatacagat atgaagcaca
     7561 ggctgcgctt gaccacgaag cctattgact caaggcgtga tcattatggc tggggcgagg
     7621 tgaccactgt ccgtcgtgat cttggggtgt ttgttgatac tggtattcca gataaggaga
     7681 tcgtggtttc cttagatgtt ttgccagagc taaaggacct ttggcctaaa aaaggagaca
     7741 ggctttacct taagcttgta gttgacaaaa aagatcgtat ctggggtttg ccagctgagc
     7801 cagagatatt tcaaaggctt gccaacccag cctatgataa catgcaaaat caaagcctgc
     7861 ctgctattgt ctatcgcttg aagctatcag ggacctttgt ttacctgcca gaaaataata
     7921 tgctgggctt tatccatcct agcgaacgtt atacggagcc tcgtttagga caggttttga
     7981 ctgctcgggt gattggcttt agagaacgtg accgtactct aaatctttcg ctaaagccgc
     8041 gttcctttga aatgctggaa aacgatgccc agatgattct gacctatctc aagtctaatg
     8101 gtggctacat gacccttaat gacaaatcaa gccctgagga catcaaagca acctttggga
     8161 tttccaaggg ccaatttaaa aaggccttag gtggcttgat gaaggctaac aagatcaagc
     8221 aggacgtgac aggaactgag ctgatatcat aaggagctgt ctgtctctca gcctgtaatc
     8281 atgagctgga tcagtgctgc taagacttat cctctatcag tatagctagc ttccttattt
     8341 tgagtgtgga gcttagctga tggcttgttt taaagcatca gtcacttttg ttgtggaaaa
     8401 agctctgtgt gggcctcttg atctagtagt ggctgcttga cagtactgct tagtgctagg
     8461 tactagctgg gctgaggagt cttgttactt tgagtctgtg acttgtttta tattaagctt
     8521 tgcctctggc aaggtttttt gttacaatga aaatcattaa tgtaaggact aagaaggtgg
     8581 aggttaggca tggaaagagc aatttttgca ggaggctgtt tctggtgtat ggtgcagccc
     8641 tttgaggagc aggcaggtat tttatcggtg agaagtggct atacaggagg acatgttccc
     8701 aatccaagct atgagcaggt ttgctcaaag acgacaggcc atactgaagc tgttgagatt
     8761 atttttgatc cgagcctgat tagctattca gatttggtag agctttactg ggctcagacc
     8821 gatccgaccg atgcctttgg gcaatttgag gacagaggag acaactatag gcctgtgatt
     8881 tactatactg atgagcggca gcgagaaatt gctgagcagt ccaagcagag cctgcaggcc
     8941 tcagggcgct ttgatcagcc gattgtgaca agcattgaac cggcagagcc tttttatcta
     9001 gcagaggact accaccaagg cttctatcaa aagaatccac agcgttatgc acaaagcagt
     9061 gctattcgtc atcaattttt ggaggaacac tggcaatgag aaaggcattt tacacttggc
     9121 tgatggctca gcgccactcg acatctaata agcctgctgc tttattagct gatttggttt
     9181 ttgaggacac gacttttcca aagcatacag atgattttga gaccatcagt cgttaccttg
     9241 aagaggaagc gaactttgcc ttcaatctgg ggcagtttga ccagatttgg gaggattacc
     9301 ttagccacta gccataggct agctctttta ggctttaaag ctgggtctta ttcccgattt
     9361 atagcaaaat ttgttataat agagttactt atagatggaa aaggaagaca aatttgcatt
     9421 attcgactga cattagcttg aatcacccag atgatctgtt agctcttttt ggtagcaatg
     9481 agcgccattt gaagatgata gaatctcacc tcaatgttgt gattcatgct agaactgagc
     9541 gagttcagat tattggtgat gatgagcggg ctgttgagct agcgcgtttg acgatacaag
     9601 cccttttagt tttggtgggg cgtggcatgg ttatcaatac ctctgatgtg gtgactgcgc
     9661 tgtctatggc ggattcagat aggcttgatc aatttgttgc tctttatgag gaagagatta
     9721 tcaaggactt ttatagcaag ccaattcgtg ttaagacatt aggacaaaag gcctatgttg
     9781 atagtatcaa gcatcatgat gtggtatttg gtattggtcc tgctgggaca ggaaagacct
     9841 ttttagcggt cacgctggct gttactgctt taaagcgtgg tcaggtcaag cggatcattc
     9901 tcacacgacc ggctgttgaa gcaggagaaa gcctaggctt tttaccagga gatttgaagg
     9961 aaaaggttga tccttacctt aggccagtct atgacgcgct ttatcagatt cttggtaaag
    10021 agcagaccat tcggttaatg gagcgtgata ttattgagat tgctccctta gcttatatgc
    10081 gtggtcggac cttagatgat gcctttgtga ttttagatga ggcgcaaaac acaaccatca
    10141 tgcagatgaa gatgtttcta accagacttg gttttcagtc taaaatgatt gttaatgggg
    10201 acactagtca gattgatttg ccacgtcata tcacatcagg cttgattgac gcagctcaaa
    10261 aattgcaggc catcaagcag attgattttg tgtatttttc agccaaggac gtggtgcgcc
    10321 atcctgttgt tgctgagatt attaaggcct atgaaactgt aggttcaaaa gtagagtcat
    10381 taaaaagcag ccctaatcag ctgcaacatc aggctaaggc tccagatcgg cctaaaacag
    10441 agacgggtca gtctacgtca ggcttaacaa cctatgagat cattggagag ctgcctaaag
    10501 aagacaaatc gtaaaaaaga gctcttcacc tgaagagcct tttatgaaag tgagggtatc
    10561 atgacagagc tattgcaagc gattatggct gatcctgcca atcgtgacta taccaaaaaa
    10621 ggtatcgaac cactttatgc agctcctcag actgctcgga tagtcattgt tggtcaggcg
    10681 cctggtattg tagctcagga gacgcgtctg tactggaatg atcgtagcgg agttcgcttg
    10741 agagcttggc tgggtgttga tgacaggact ttttatcagt cgggcttgtt tggcgttctt
    10801 cctatggatt tttattatcc aggtaaggga aagtcaggtg atttgccacc gcgaaagggc
    10861 tttgccgcca agtggcatgg tccgctaatg gctctgatgc ctcatgttaa gttggtggtg
    10921 ctggtcggac agtatgccca gcaatattac cttggaaaag gttgcaggcg taatctcacc
    10981 gaaacggtcc agcattttga ggactatctt ccggattatt ttccccttgt ccacccgtct
    11041 cctagaaatc agctctggtt agctaaaaac gcttggtttg aagaggagct gatccctgtt
    11101 ttaaaggata aggtaaggca gattttacgc gactaggaca gacagtcata ctgttaggtg
    11161 agttagattt tttgtaaaag gagagtagca gtggcaagct tttttgaaaa actagcagag
    11221 catagctacc ttgagacaga gcgtctatgc ctgcgtccag tgaccttaga tgatgctaat
    11281 gccatgtttg attatgcttc tgatgaagag actgtcaggt atagctttcc agccaatcag
    11341 acgattgagg agacccgtca ggtcattgct tctgtctatt tggctagtcc acttggacgg
    11401 tgggggattg tgttaaaggc aacaggagac tttattggga cgcttgatct tcatcatata
    11461 cagctggatt taggtagagc tgagattggc tattgtcttc ataagcatca ctggggaaga
    11521 ggctatgcga cagaggctgt caaggctgtg ctggtcttgt gttttgaagc tttaggcatg
    11581 aattgtgtga ttgctaagca tgataaggac aatccggctt cgggacgtgt catggcaaaa
    11641 agcggcatgt gcttttcaca tgaagagcca tatgctaagc gggatcacct tgattccaac
    11701 cgttttgtga cagtgctgca ctattattta accaaagaag attatgacca gcagaaatca
    11761 ctggcatcag ccaataagcc agatcgttat ctcaacaata gctttaagaa cagctagcgc
    11821 tacctacagg agctgcctag gaattcatct ttagacgatt gaagtgatct gcaagattta
    11881 tctggtatta tagtaggagc cccagctatc taagagacct gtattctgcg cagcaggcta
    11941 ggtattccag aagcagctac tggtgtatca acggtcatgt cattgttcag gcttcttttg
    12001 gagcaggcta gactaatgtc tgctttttct tttttcttgt ggtataatgg aaagaaaata
    12061 ctgaaatgat gttgaaagga taagaggtat caagcttttt gacctagcgg tgtggttttt
    12121 gtttggaccg gtcttgctag gacctcttca tataatgatg tatatagaga tgattgatga
    12181 aaccaagcag gtttctcaag agatgatgga gcaaaccatt gatttgctca attttgctgc
    12241 caaaacaatt ggtaaagagg acaaggaaat ggcggttacc tttgtgacca atgatcgaag
    12301 ccatgccttg aatcttgaat atcgtgatac tgatcgtccg accgatgtga tttctctgga
    12361 gtacaagcca gagcttccga tcgcctttag ccaagaggat ttggagcttg atcctgactt
    12421 ggcaggtatg atacaggagt ttgatgctta tattggggag ctgtttattt ctgttgacaa
    12481 agcccatgag caggcagaag cctatgggca ttcctttgag cgtgagatgg gcttcttggc
    12541 tgttcatggc tttttgcata ttaatggata tgaccattac actcctgagg aagaaaaaga
    12601 gatgtttacg ttacaggaag agattttgac tgcttatggc ctcacaagac aataataaac
    12661 gtaaatggaa aaacagaacg gttatcgcta gcttagaatt tgctttgaca ggggttctga
    12721 cagcctttaa ggaggagcgt aacctaagaa gtcatctttt gtcagccctg ttagcctctt
    12781 tggctgggat tgtttttggt atttctgcaa tagagtggct gtttttattg ctggctattt
    12841 ttttggtgat taccttagag attgttaatt cagctattga aaatgtggtt gacttggcaa
    12901 gcgattacca tttctccatg ctggctaagc atgctaagga tatggccgca ggtgctgtct
    12961 tggtcatttc aggctatgct gttttgacgg ggctgattat ctttgttccg aaaatttggc
    13021 gaatgttatg ccattaaaaa aatgaaagga aatgggctat cctgtgtgat attgcagcgc
    13081 aggaagggag gtataagctt taggaaggca atcaggtgaa tggcctgcta cttggtcctt
    13141 gccttggctg atccctttgg gcccttaata gcttatgttt aaatcaggct ttgttgccat
    13201 tcttggccga ccaaatgtcg gcaaatcaac gtttttgaat catgtcatgg gacaaaaaat
    13261 cgccattatg agcgataagg cgcagacaac tcgcaataaa attatgggga tctataccac
    13321 agagacagag caaattgttt ttattgacac gccaggcatt cataagccta agacagcctt
    13381 aggtgatttt atggtggaat cagcctatag taccctgcgt gaggttgaga cggttctttt
    13441 tatggtgcct gctgatgaaa agcgtggtaa gggtgatgat atgattatcg aacgcctcaa
    13501 ggctgctcgt attccagtta ttttggtgat caacaaaatt gacaaggttc acccagacca
    13561 attattggag cagattgatg atttccgtag tcagatggac tttaaggaaa ttgttcctat
    13621 ttcagcactt caaggaaaca acgtcgaaac gctcgttcag ctcttaaagg ataaccttga
    13681 agagggcttc cagtatttcc cagaggatca aatcactgat cacccagagc gctttcttgt
    13741 ttctgagatg gttcgagaaa aggtgcttca cttgacacag caggaggtgc ctcattcagt
    13801 tgctgttgtg gtcgattcga tgaagcgtga tgaggtgact gacaaggtgc atatccgagt
    13861 taccatcatg gtagagcgtg acagccaaaa aggcattatt attggaaaac aaggcgccat
    13921 gctcaaaaaa atcggtaagc tggcaaggcg tgatattgag ctaatgctag gcgataaggt
    13981 ctatctggag acctgggtca aggtcaagaa aaactggcgt gacaaaaagc ttgatttggc
    14041 tgactttggc tataataaga aagagtattg atacctagta ggcgtcaata gtccctcgac
    14101 cttgaaacga gagggagaga gttgaggtat gggagacctt agtatttcga gctctgaagt
    14161 gggaaagcga ggtagttcta gtggatcttt ttaacctagg tttggatatt aaaagtagca
    14221 tcctacggac aggcttgttc cctcttgact tagattagaa gtacaaaaga aattttacga
    14281 ggttgattaa ccaagcagac aatcattctt tatctgcttg gttagcctta gccgtagtgg
    14341 tttggcagac agagaacagt aaagatatta atcgtagact aaatgaggtg atagagtcct
    14401 aaaaagcctt tatggcacag gactacgttt ctgatattcg ttcaaagata ggcattattc
    14461 ttatttcttc ctcgctgagc gttacctcta cattgagaag taaacaatca atggtctttg
    14521 attgtttacg ggattttatg ttgccatcaa aggcttcagt gacaaatgcc ttggtttctt
    14581 ggttctgttg ctacgcacaa aagtagcttt tcctcttgtt tatagtctag gataagggta
    14641 ttgacttgta gtctagataa gcctagcttc acacaagccc tgtctttctt tttttccttg
    14701 tgtagtgctg tgatgacttg atacttattt atctcaagtg ttgttaaatc aatcctcttc
    14761 attctactag tgtaacagat ggggcaattt caccttcgac ttaacaaaga tatgatcact
    14821 ttcgaatggt ataataaaaa aattttaatc ataaaaatgt tgacatgtag tacatatagt
    14881 ggtataatca ggcttaaaag agtagattag ttttactttt tgtgattaga aaaacaaaaa
    14941 tactaacatt attatatttt tgttagttat atttgctgga agatattttt attatcataa
    15001 catctaaaga aatcaataac atatatttaa ttgttaaacc ttggttagag ttgaatttta
    15061 atgtgtataa gtacttataa aataaatagg aaggaggaaa gaacaatggc tgatgaagta
    15121 ttaaaattgc aaatgttgtc tgttgaggaa gaaacagatg aagttgatgg tatgcgtttc
    15181 agcactacta gtctaagttg gtgtggtaac tggagtgcga ttagtgcatt tggttgctag
    15241 tttgtttatt ttgattttta ttgagcctta taatatctgt tattgtggaa ttgattgtac
    15301 ccattggata ttataaggct ttttttgtcc caattataaa aagagagatt atggtacgac
    15361 ttatttatta tcaatttaat tatagacgaa gagaatggtc aggtgctttt cctgtattat
    15421 ttagtgcagg tgtagtagta ggtacatgtt ttacaatact gtttaacgtt ttaggaaaca
    15481 ctgaattgtt tagtagagta atccctgctc cattatttat tgcaccggta ttttttggtg
    15541 gcttaacgtt attttttctt atttccacac taattaaact tctacttaat atttttaaag
    15601 atgaatacag actttggtat atattaggag ctgatagaag acagttatca atgctagttg
    15661 gaggtcagtt tgcaattgtt actttgattt ctagttttat aggttctttt atatcaatat
    15721 tatcagcgaa gagttattat tatctcatac aaggacgagt gggagtcgac tatttcccct
    15781 ccatctcaat tcagttcaat ttattagctg tatttcttac gataatcttt ttaacattag
    15841 tatgttttgc tagcgctact tataatgcat ataagttatt agatgaaaat attatatttg
    15901 aagaagataa aggagagaaa aaaatatata aatttactaa atttggtata tttggaatta
    15961 acgtgtttct atggctttcc ttggttgttg gttctgttgt agtgccatat ttagatttac
    16021 caggaggagt tagttataaa ttgtcattca tgtcttctgc tatattttat cttctagtga
    16081 ttcatatact ttttttgaag tacttatcac catggattga attacgaatt gttcaatttt
    16141 tatttaaaaa agtgaaaggg tttgcaacag ttctatctaa gtggagtgta attgaaaaga
    16201 aatatttttt aagttcagtc acaatatcca tggtgacagc catta
//
LOCUS       DARYSY010000048        15225 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYSY010000048 DARYSY010000000
VERSION     DARYSY010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15225
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..321
                     /locus_tag="TVR04_001505"
     CDS             <1..321
                     /locus_tag="TVR04_001505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270182.1"
                     /translation="KSEEELRNYEYEVSLVKALKNSYKGIEEITITNPHYTIPPGNWS
                     CDLELIFNDTSKISYRIGHNVDDDSNYNGALTYRQSDFLKRKRGTTDIFVKVTFSDGT
                     ERSV"
     gene            324..1637
                     /locus_tag="TVR04_001506"
     CDS             324..1637
                     /locus_tag="TVR04_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270183.1"
                     /translation="MGDFLYTDRQLNVLNQGKNVYSVNPEFAKREGYPVIMDTISESP
                     SLNEMKIKNVITVDNQDFQVIKTYSDPKTGFDGMAVAPIIDDKIDLKHVAVVAAGTDP
                     NAKDLKLRIATVSPVGMEPMAATVTISQDLVSAGLAKYTNLSPQYKSLEAFIETVQDL
                     PDVRISQLTGYSQGAYVTKAGAKYHIPATTFNAWFNYHALTTEELAFLQKNPHMFISY
                     RKKNDTVTSYNDLNKPWKYYDDYGTIHWVEGKSHSISDWYFDSRTGAVLSKKNGDMVV
                     NEYSRIYSHAVQGMTHLKSLKAHWQSTGKGLSSSEELFLDAAQGMILGSSMAKAAREG
                     ADEALDHKTVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQ
                     SKVSKMSALATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            1619..2011
                     /locus_tag="TVR04_001507"
     CDS             1619..2011
                     /locus_tag="TVR04_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270184.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKAYQKREDSLSERRR
                     VLDDLINSEYQKMGAFLKRLDLSVNAASDFFKELDRLKDQSKAEFHLQRAALEEERAQ
                     STKTFRQEQDQREAELLDMRRAYANTNN"
     gene            1992..2282
                     /locus_tag="TVR04_001508"
     CDS             1992..2282
                     /locus_tag="TVR04_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270185.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQAEAI
                     KKTFKDQVKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            2582..2869
                     /gene="groES"
                     /locus_tag="TVR04_001509"
     CDS             2582..2869
                     /gene="groES"
                     /locus_tag="TVR04_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1270186.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
     gene            2937..4562
                     /gene="groL"
                     /locus_tag="TVR04_001510"
     CDS             2937..4562
                     /gene="groL"
                     /locus_tag="TVR04_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1270187.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGVGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(4898..5368)
                     /locus_tag="TVR04_001511"
     CDS             complement(4898..5368)
                     /locus_tag="TVR04_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1270188.1"
                     /translation="MLEVIKNWVNICVKEDDKILLLNRQHDDFPGWIQPGGKVNASES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEAFEGKLLTESREG
                     QPQWHPIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTVTHLYD"
     gene            5954..7588
                     /locus_tag="TVR04_001512"
     CDS             5954..7588
                     /locus_tag="TVR04_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270189.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFVVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKTYDGKNHTLDLRVAFKTFTVTSNVRDGELYVDGERV
                     ETLKAGQLQLEEYPVTETAKAYIKKTFPDGELTSSKYSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7729..8622)
                     /locus_tag="TVR04_001513"
     CDS             complement(7729..8622)
                     /locus_tag="TVR04_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1270190.1"
                     /translation="MTIANKPEMGFQVSLTNPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLRFDQEDYPDKGILMGKPALVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LERRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLT
                     QEMIRVTAPSKSFEEGLQQLN"
     gene            complement(8606..8797)
                     /locus_tag="TVR04_001514"
     CDS             complement(8606..8797)
                     /locus_tag="TVR04_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270191.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVALAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9040..10782
                     /locus_tag="TVR04_001515"
     CDS             9040..10782
                     /locus_tag="TVR04_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1270192.1"
                     /translation="MNKPLIKSCLLALLTLAGLTNMAAQADVNTYNQDRTYNDTHYYN
                     YYDNTRDTADNGIADWGRVTRYHYYRETYYQLEAERQQLVRTYLELKAAYDNQIALNS
                     QQLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNLQSYQTLLQQLSLADFVSQ
                     HKDRLDALTRLDTERARLIDAWWESDSNYSDLNTNLTLVNGYIKELNQALQELLKDHQ
                     GKMTSDLRTLEDRQAELARWLTDIESRPKRQATSHARGSQTHWRSASRADVALWNELR
                     NEGDYASAMTDDALPSQPYRADLTAVHDLEALQAQSDKAHRLRAKEIVFTLQRSNISR
                     QGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMTDDQY
                     KEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQTPYA
                     FIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQYYHI
                     DLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRTFPRYGTYAA
                     NDSRNTFYPRYSYA"
     gene            10923..11303
                     /locus_tag="TVR04_001516"
     CDS             10923..11303
                     /locus_tag="TVR04_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1270193.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEAVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKSLQTAFA
                     HQGGPDGLLFQIDGVAYSKHISVS"
     gene            11341..13674
                     /locus_tag="TVR04_001517"
     CDS             11341..13674
                     /locus_tag="TVR04_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1270194.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTRGQSVLQRSKSYGAKRKKQPVWLQRLEAILPLSQNPIRRFLRRYHIGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIENATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETVPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSDTKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKIDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13723..13875
                     /gene="rpmG"
                     /locus_tag="TVR04_001518"
     CDS             13723..13875
                     /gene="rpmG"
                     /locus_tag="TVR04_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1270195.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            13887..14063
                     /gene="secE"
                     /locus_tag="TVR04_001519"
     CDS             13887..14063
                     /gene="secE"
                     /locus_tag="TVR04_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1270196.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14453..14998
                     /gene="nusG"
                     /locus_tag="TVR04_001520"
     CDS             14453..14998
                     /gene="nusG"
                     /locus_tag="TVR04_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1270197.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4480 a         2938 c         3575 g         4232 t
ORIGIN      
        1 aaatctgaag aagagttacg gaattatgag tatgaagtta gtttggtgaa agcgttaaaa
       61 aactcctaca aagggattga ggaaatcacc atcacaaatc cgcactatac tataccacca
      121 ggaaattggt catgtgatct agaactcatc tttaatgaca cttctaagat ttcctatcga
      181 attggccata atgttgatga tgattctaat tataatgggg cacttaccta taggcaatca
      241 gattttttaa aacgtaaaag aggaactaca gatatatttg taaaagttac tttctcagat
      301 ggcacagaaa ggagtgtttg attatgggtg acttccttta tactgatcgg cagctgaatg
      361 tattaaatca aggaaaaaac gtttatagtg ttaatccgga atttgctaag cgagaaggtt
      421 atccagtaat tatggatacc attagtgaat ctccttcatt gaatgaaatg aaaataaaaa
      481 acgttatcac agttgataat caagatttcc aagttattaa aacctattct gatcccaaaa
      541 caggttttga tggtatggct gtggcaccga ttatagatga taaaatcgat ttgaaacatg
      601 ttgcggttgt tgctgcggga actgatccga atgcaaagga cttaaagctc cgtatagcta
      661 ctgtatcacc tgtaggaatg gagcccatgg cagcaactgt taccatatca caagacttag
      721 tttctgcagg gcttgcaaaa tatactaacc tatctccaca gtacaagtcg ttagaagctt
      781 ttatcgaaac cgttcaagac ttacctgatg tccgtatttc tcagctaaca ggttatagcc
      841 aaggggctta tgtgactaag gcgggagcaa aataccatat accagcaaca acatttaatg
      901 cttggtttaa ttatcatgcc ctcactacag aagagttagc ttttttacaa aagaacccgc
      961 atatgttcat cagctataga aaaaagaatg atactgtgac gtcttataat gatctcaata
     1021 agccttggaa atactatgat gattacggta cgatacattg ggtagaagga aaaagccata
     1081 gtatctctga ttggtacttc gactcgcgaa cgggtgcagt tcttagcaaa aagaatggag
     1141 acatggttgt caatgagtat agtcgaatct actcacatgc tgttcaagga atgactcatt
     1201 taaagtcttt aaaggcgcac tggcagtcta ccggcaaggg gctcagtagt tctgaggagc
     1261 tctttttaga tgcggcacag ggaatgatcc taggctcgtc catggctaag gctgctcgag
     1321 agggggctga tgaggcactg gatcataaaa cggttgccga cgcaaagctt atggaagtgt
     1381 ggtcggcgat tgattttaac gcttttcatg agctgcccta ctatgaggta caggccttgt
     1441 ttgcttctta tgggatcact tatgaccgct tcgtccgaga ctttcaggac tatactcaat
     1501 ccaaggtcag caagatgtca gccttggcca cagactttga aaacctgaat agagatattc
     1561 agacagttat tgatagcaag cttgaaacgg atcaacagtt agcaggagag tttagagcat
     1621 ggcagacaga attgtagagg aagtggctat ctatcgtaag ctgcgggaga tggatgatgc
     1681 cgagcaggac tttctgcgcc agaaaaaagc ctatcagaag cgtgaagaca gcttatccga
     1741 aagaagacgt gttttagatg atttgatcaa ctctgagtac cagaagatgg gtgctttttt
     1801 gaagcgttta gacctatctg tcaacgctgc gtcagatttt ttcaaggaac tggatcgctt
     1861 aaaggatcaa tccaaggcag agtttcacct ccagcgggca gctcttgaag aggagcgagc
     1921 acagtcaacc aagacttttc gtcaagagca ggatcaaaga gaggcagagt tattagatat
     1981 gaggagagct tatgctaata ccaataactg agtattatat cgaagaagaa tacgcctatg
     2041 ccctgaggct aatgcgtcaa atgctggagc gtcaaaggat tgccacagtc gctaggcttg
     2101 caaacagcca agctgaagcg atcaaaaaaa cgtttaaaga ccaggtcaaa gcgactgcca
     2161 gccaaactaa ggaaagcctt cagatcatgg aagggcagct agatacggcc ataaaaggag
     2221 cggtcagaga tcagctggag caggtcgtaa agaagaagct gccaaaatac aacaagctat
     2281 agtcaaatgg tgtcatttat aagagaccgt aggggttcaa tcaataccta ccaagcaagt
     2341 attatcaaaa gaggcgatca gcctccagag cttttgtcct gttatctttg aaaggtgata
     2401 attgtataca gggtgaccga tagctaaaga cgagagagga ccggctgggt cttttctttt
     2461 ttcctagact ttttttcttg actatttttg accaagtgat aaaatagaga agaaagttag
     2521 cactcataaa acaagagtgc taacaaaata gataatctag tcattattgg aggtactatt
     2581 catgttaaaa ccattaggag atcgtgtggt cctaaaattt gaagcagaaa aagagcagac
     2641 cgtcggtggc tttgttcttg ctgctagtca caaagaagcc actaaagtag ggacagttgt
     2701 agctgttagt gagacaggta ttcgtactat tactggagac attgttccac caagtgtggc
     2761 tgtaggtgac aaggttttgg ttgaatatgg atcaggctta gaggttaaag atggcgatca
     2821 agagcttgtc atctgtcgtg aagctgacat tcttgcagtt ttagcttaat tgtgaatccc
     2881 tatcatttca ggtaggatta acagatatac attcaaatag gaatagagga aataacatgg
     2941 caaaagatat aaaattttca gcagatgctc gtgaaagcat ggtacgtggt gttgatattt
     3001 tggcggatac cgttaaggta acccttggcc ctaaagggcg taatgtagtc cttgaaaagg
     3061 cctttggttc tcctttgatc acaaatgatg gtgtaacgat tgccaaagag attgaattag
     3121 aagatcattt tgaaaatatg ggggctaagc ttgtatcaga ggtagcttca aaaacaaatg
     3181 atattgctgg tgacgggaca acaacagcta ctgttttgac ccaagcgatt gtgcgtgaag
     3241 ggcttaaaaa tgtaacagca ggtgctaacc caattggtat tcgtcgtggg attgaagcag
     3301 cgacaacgac agctgtcgag gccttaaagg ctgttgctca accagtatct ggaaaagaag
     3361 ctattgctca agtagcttcg gtgtcatcac gttctgaaaa ggttggtgac tatatttctg
     3421 aagctatgga gcgcgtggga aatgatggtg tgattactat tgaggaatca cgtggtatgg
     3481 aaacagagct tgaggttgtt gagggaatgc agtttgaccg cggctatttg tcacaataca
     3541 tggtcactga caatgaaaaa atggttgctg atcttgaaaa cccatttatc ctgattactg
     3601 ataagaaaat ttctaatatc caagacattc ttccattgct tgaggaggtg cttaagacta
     3661 gccgtccatt gttgatcatt gctgatgatg ttgatggcga agcccttccg accctagtgc
     3721 ttaataaaat tcgtggtacc ttcaatgttg tagcggttaa agcgcctggc tttggagatc
     3781 gtcgtaaagc gatgcttgaa gacattgctg tcttaactgg tggtacagtc atcactgagg
     3841 atcttggtct tgaattgaag gatgctacaa tggctgccct cggacaagcg gctaaagtaa
     3901 ctgttgacaa ggataataca gtgattgtag aaggtgcggg cagctcagaa gctatttcaa
     3961 accgcgttag cctgatcaaa tcacaattag aaacaaccac atctgaattt gatcgtgaaa
     4021 aattacaaga gcgcttagca aaattagcag gtggtgttgc agttatcaag gtgggtgcag
     4081 ctactgaaac cgagctaaaa gaaatgaagc ttcgtattga ggatgcgcta aatgcaacac
     4141 gcgctgcggt tgaagaaggc atcgttgcag gtggtggtac tgctcttatc aatgtcatgg
     4201 ataaggttgc agcccttgag cttgatggtg atgcagcaac tggtcgcaat atcgtgcttc
     4261 gtgcgcttga agagcctgtg cgtcaaattg cttacaacgc tggctatgaa ggttcagtga
     4321 ttattgataa gctgaaaaat agtgctgctg gtgttggctt taatgcagca actggtgaat
     4381 gggttgatat gattgctaca ggtatcattg atccagtcaa ggtaacacgt tcagcacttc
     4441 aaaatgcagc ctctgttgca ggtcttatcc tgaccaccga agctgttgtt gccactaagc
     4501 cagagcctgc tgcaccagca atgccgcaag gaatggatcc aggcatgatg ggtggcttct
     4561 aacaagaagg cctgttagga taggctagtt gttctatcat aggatatcaa aataattgat
     4621 aaagactccc ctgacgttaa ggtgatatga ttatccctaa aacgcctagg ggagcttttt
     4681 tattgcttac cttagcaagc ttaacgaaca tgtgacttgt ctttgtctta aatcattgac
     4741 aacaattaaa atgaccagtg tgaactagtg cttttctgaa ggcaaaaaag caaaagccct
     4801 gagaaatcaa ggcttttgca ggagatttat gaaaaagaaa aatttaggat agtgcaagta
     4861 taagctagtt tccttaagga aagcttaact gaagcaatta atcgtagaga tgggtgactg
     4921 ttttgacgac ttttttctcc ttgtcagacc aataatgaag acgttcaaaa gatccttgtc
     4981 gccagtagag cggtagcctt tgtcgaatgt cctcttgcat gtctagctta tctaagtcag
     5041 caatcgggtg ccattgtggc tgaccttctc gtgactctgt tagcagcttg ccttcaaagg
     5101 cttcgcagag aaaatcataa taaacatagc gctcaggctt atcaggattg gtaaagcctg
     5161 agattccctt taattgcaga tttaaggcgg ttaagccggt ttcttccttt agctcacgca
     5221 ctgccgcttc aaaaaaggat tctgaggcgt taaccttgcc acccggttgg atccagccag
     5281 gaaaatcgtc atgctgtcgg ttgagaagta ggatcttgtc gtcctccttg acacagatat
     5341 tgacccaatt tttgatgact tcaagcatta gtgacctcgt ttttagtttt agtatagcat
     5401 agataacagc gaggatacca taaaaaaaca ccttacaaga tatttgatga tcaatcctcc
     5461 ttgaattaag ctttctttaa gcaagtgtgt gtatactggc tataatccta aataattggt
     5521 tacctaatga taactaattt tttcataacc tccttcctaa aaacgatgtc agggcagtcg
     5581 ggattgattg ctgttatggc atcgtttttg ttgtgctttg atagcaaatc tagctgtatg
     5641 tcaaatagcc tatcgggatt gatgaagatg atcagcaggg gtctcttgga tctaggctat
     5701 gctgacgttt catgagaaac agctcttgat tatcagctta ggcagtattt agtgtggtca
     5761 ttttaacctt ttaggtcttt agtgagctcg tcaaaattaa ctgttgaaag gactataccc
     5821 caaaaaatag gccttattag ctgttaggcc ctgagcagct ttgtgctggc tcatttttaa
     5881 tgtgttagtg tttacacaaa taattctcat tttttgatat aatagaaaag gtaaggaagg
     5941 gtaggagata aggatgacaa gattctttca aaaaaaacag gccaaaagct tagcaattgg
     6001 ttttgttagc ttatttgttg tactaattgg gtatggggct tttcattatt ctaaggccag
     6061 tcgtatcaat gcctacctac aagcaaggtc atcaggctct gggcaggtgc ttgaaaatat
     6121 caaggaatac ctcgtgtggg cagataccaa tgagcagctg accaatgatc aagcaagata
     6181 caccagcttt aagagataca gtaaggcaga gctagtaagc aagcgtcagc agctgcaaac
     6241 agcaactgca gctgatgata tgtatgtcaa atcggttggt cgcaaatttt tgattttccc
     6301 tgattatcgc atagcagtga agcctgtagc cttgaccatc aagaccaatg tgccaaatgt
     6361 tgatatcttg ttgaaccata aaaagattgc tgtatcacag tcagaggatt ttagcacaac
     6421 tattgaaaga ctgccggctg ctgattataa ggcgagtatt aatggctatt ataaggatcg
     6481 taagattaag gttagtaaga cctatgatgg caagaaccat acactagatt tgagggttgc
     6541 ctttaagaca tttacggtaa ccagcaatgt cagagatggc gagctttatg ttgatggtga
     6601 gcgcgtggaa actttgaagg ctgggcagct tcagctggaa gaataccctg tgacagaaac
     6661 cgcaaaggcc tatattaaaa agacctttcc tgatggcgag ctaacctcca gcaagtattc
     6721 ccttgctcct gttgctgagg gctcccagct agagattaac attgatcacc tcttgactga
     6781 ggaacaggcg ggacaggtgt tggtggcagc ctttgatcaa ttgctcacct atctcaatca
     6841 agggcaggat ccagcaggtc tttcaactgt ttttgagcaa ggggctaata atgcttttta
     6901 caaaggcttg aaggattcca tcaaagcaaa atttcaaact gataccagaa aggcttctcg
     6961 gttaagcatt ccgtctattt tgttaagtaa gctaactcaa attggtaagc agtcttatct
     7021 agtggacttt acagctgttt atgattttgt ttacgataag gaaactgatc ctgaaaaagg
     7081 cacttcaggg aatgttcgtc aagacctgac tggtaagttg accctgaaaa aatctgggga
     7141 tagctacctt gttagtcagt ctggtcctaa aaatattaca gttgccagcg aaaaaaatca
     7201 ggtcaagccg tctattttcc cagaggggct agtgggaacc tggataggac atcgctcgga
     7261 catgaccttt acgatgatat tggctaagga cggcagcatc acaacaacca ttggaaacaa
     7321 aaatgggaat ggctcacaga ccactaagtc tgctaaaatt accaaggtag aggaaaaagg
     7381 agatggcttg ttcctctaca ctgtagctcc agatgctgat atagcagctc ttgttccagg
     7441 aggtggattg ggtggtgtca atgtcaaata cgcttttggt gtcaaatgga gtggagatgt
     7501 cgctacgata gtggtttggc agacagcaaa taatgcggca tttgattaca gtaagccaat
     7561 gcttggccct gacatgaaaa agcaataagt actttaccct acaagttggt ctagcattta
     7621 ttgctaggag gaatcagcat aaagaaaaag cctctctttt aatcttttgt ggttaagaag
     7681 agaggctttt tagtataggg ctgactgtat gaggagcaac cgatgtaatc aatttagctg
     7741 ctgtagtcct tcttcaaagc ttttagacgg ggcagtgacc ctaatcatct cttgagtcaa
     7801 ggggtgtcta agggttagct gatgagcgtg cagcatgaga cgctccgctt tttgcctgct
     7861 atagagggga tcaccaatta gagggtgttt atgatgagcg agatgtactc tgatttgatg
     7921 tgttcgtcct gtctctaggc gacagttgac taggcaggtc tgatcaaagg cttgtaataa
     7981 ggctagatgg gtgattgcct cttgcccatg cttactatca accacacgct tgcgcctatc
     8041 gtggcggtga cgtccgattg gatcgcgata ggttactgtt tgctgctcta gctgaccttc
     8101 gattagggcc caataatctc gcttaatgtc tcgacgctcc aataggcgat ttaagatcgg
     8161 aaggataaag ggatttttag caaagagaat cgctccgcta gtctccatgt ctaagcgatg
     8221 aaccacatag caggtcttgc cagtataggc agagacatgg ttgagcaagg cgagctcagt
     8281 aggctcattg ccatgtgttt tcatgccttc gggcttgttg acaatgatga ggtgttcgtc
     8341 ctgatacagg caatccacta gggcaggctt gcccattaag atgcctttat cagggtagtc
     8401 ctcttggtca aagcgtagct tgatgtgatc accctgcttg acagggctct gccagttaat
     8461 cagctcatca ttgacccaaa catgcttttt gatgcgcaag aaatgtctaa ttttacgggg
     8521 aattaatagc ctatcttcta ataactcctt gacagttgtt gcttgatagg ggttagtgag
     8581 ggagacctga aagcccatct caggcttatt tgctattgtc attgagccag tcatggtatt
     8641 tttcaatcaa attgatagcc atttgggtgg caagagctac agagaaggct tcggttcctt
     8701 cgcgctcgtc actcgcaacc tctaagcgtg tctcatcata gacagccttg aggctctctg
     8761 ctgacagggt ttctttaaaa gcttgaaatt tgttcatgat catgtcctac ctttctaaac
     8821 gtttgtgaca atgctattat aacatgtttt tcgtcaaagc taatcatttg ctcgatgatt
     8881 tgtgctgcgc taacagcgtg attcttttga gaaaagataa gattagctat ttagctattg
     8941 tgaaattgtc tgtcttttat tatactaaga atagtctgat aaatatatta tttaaggaca
     9001 cgataacatt gggattatga atgatttagg agaatactat tgaacaagcc attgataaaa
     9061 tcctgtttgc ttgctctatt gaccttggcc ggcttgacca atatggcagc acaggctgat
     9121 gtcaacactt acaaccaaga taggacatat aacgatacac actattataa ttactatgac
     9181 aacacgaggg atactgctga caatggtatt gctgattggg gtcgtgtgac acgctatcac
     9241 tattacagag agacctatta tcagcttgag gctgagcgtc agcagcttgt taggacttac
     9301 ttggagttga aggctgcata tgataatcag atagctctta acagtcaaca actacagcag
     9361 taccagtctg gctggtctga tctccaatca cgctttgagc agctcaggaa aaccaatcct
     9421 gttgtaggcg gtgattatcg gattgttgaa ctagaaggca atcttcaaag ctatcagacc
     9481 ttgctgcagc agctttcttt ggctgatttt gtcagccagc acaaagatag actagatgcc
     9541 ttgactagac ttgatacaga gcgagctagg ctcattgacg cctggtggga aagtgatagc
     9601 aattactcag acctcaatac caatctaaca ctggtcaatg gctatatcaa ggagctgaat
     9661 caggctttac aggagcttct taaggaccat caaggtaaaa tgacatcaga tctgcggacc
     9721 ttggaggacc gacaggccga gcttgctaga tggctgacag acatagaaag caggcctaag
     9781 agacaggcta ccagtcacgc tcgtggttca cagacacatt ggcgatcagc ctctagagct
     9841 gatgttgcct tgtggaatga attgcgaaac gaaggagatt atgcttctgc tatgacagac
     9901 gatgctttgc catcgcagcc ttatcgagca gacttaacag ctgttcatga tctggaagcc
     9961 ttgcaagcac aatctgataa agcacaccgc ttgcgggcaa aggaaattgt ctttacattg
    10021 cagcgttcta acattagtcg tcagggcgat atagatttgt caggagccat tacagcattt
    10081 atcaaagaaa agcttctcgt cactccaaat gcgcgtgggg tatcatctgg ctttaggtgg
    10141 caaatgcaaa cctatgacaa tgaacgctta accatcactc taatgcctca atattatatg
    10201 actgatgatc agtacaagga gtattacgac cacctcaagg cttggacagc tcagcatatc
    10261 cagtctaccg atacagaggt tgagaaaatt gataagattc aagactatat catgacaaac
    10321 taccactatg cgaccggcaa ggttggagga gtgacccgta ctggcatttc tgtgcagacg
    10381 ccatatgcct ttatcaagga caaggaggct gtttgtcagg cctatgcgca gatgtttaag
    10441 gacatgggac gactagctgg acttgatgtt cattatattc aaggctatgg agacccagtt
    10501 ggcggcttat caagtctaca tgcttggaat atcgtcaagg ttgatggcca atattatcat
    10561 attgacctga cttggaatga tactattgac agcaccaatc acaatcatac ctacaccctg
    10621 cgaggcaatg attttatgag caaaacacat ttgtggaatg ctgcctatgc gatctcagat
    10681 agtgactatg ctgcttatcc taggaggacc ttcccgagat atgggaccta tgcggctaat
    10741 gattcgagaa acacatttta tccaagatac agctatgctt aataacagct aatgtcatag
    10801 aaagccctgg aaagcttact tgattctttc agggcttttt gagatgtcat ggtttttggt
    10861 ataggatttt gaaagaaatt gttataatag gataaaatgc ttatgtaaca ggagaaaata
    10921 aaatgaaaag tattagacgc tatgatgtca atgaagagtg ggcacatact ggcttagtag
    10981 aggcaggcga tttttatttt ttaaattatt gtgtaggaaa tgtcggtcaa gatatagagg
    11041 ctcaaattaa cggtgccttt gatgaaatgg agcgtcgttt ggggctggta ggtctgacgc
    11101 tggaagctgt tgttcaaatg gattgcttgt ttagagacat ttggaatgtg ccagttatgg
    11161 aaaaaatcat caaggagcga tttaatggca aatacccggc tcgtaaatct cttcaaacag
    11221 cctttgcaca tcagggtggt ccagacggct tgctatttca gatagatggg gttgcttatt
    11281 caaagcatat ttccgtatcc taaacaatat gacttggagg cttagtagta tcataaggct
    11341 atgacatttt tagaattatt acaaaagaaa ttttttccaa aaaaatacca agaaaaacag
    11401 gccttaaagg aaagggcagc acagcatatg gctgacaaag aggctactac tcaggctact
    11461 gccactgctt tggccgatca ggaggcacaa gcagggcaga ctagggggca atcagtcctt
    11521 caacgcagca agtcttatgg ggctaaaagg aaaaagcagc cggtctggct tcaaaggcta
    11581 gaggcgattt tgccattgtc acaaaaccct attcgccgct ttcttcgtcg gtaccatatt
    11641 ggtaaaatcc tgttgatttt gatgggtacc tttgtcttgt tgctggggtc ttaccttttt
    11701 tacctctcaa agacagccaa ggtttctgac ttgcaggacg ctcttaaggc gacgacagtc
    11761 atctatgacc gcaagggaga atatgcaggc agtctttctg gtcaaaaggg aacttatgta
    11821 gagcttgacg ctatttcaga tgatttggaa aaggcggtta ttgccacaga ggaccgtacc
    11881 ttttatacca acaatggtat taatttcaag cgctttttat tggctattgt gaccgcaggc
    11941 cgctttgggg gtggctcgac cattacccag cagttggcta aaaatgctta tttgtctcag
    12001 gagcagagca ttaaaagaaa ggcgcgtgaa ttcttcctcg cacttgagct caccaaaaaa
    12061 tacagtaaaa atgacattct gaccatgtac ctgaataatt cctactttgg taatggtatt
    12121 tggggtgttg aggacgccag ccaaaaatat tttggtacct cagcagctaa tctaaccttg
    12181 gacgaggcag caacccttgc tggtatgctc aagggacctg aaatttacaa tccctattac
    12241 tcaatcgaaa atgcaactaa tcgtagagat accgttttgt cagctatggt tgacgctggg
    12301 aaaatcagca agcagcaggc acaagaggcc caagctattg gtatgggcaa ccgtttagca
    12361 gacacctatg tcggcaaaac agatgattat cagtacccat cttattttga tgctgttatc
    12421 aatgaggcaa tctcgcgcta tggcatctca gaaaaggata ttgtcaatga tggctacaag
    12481 atttacacag agctagatca aaattatcaa gcaggcatgc agaccacctt taatgaggat
    12541 agtctatttc ctgtgtctga gtttgacggc agctcagctg aggcagctag tgtggctcta
    12601 gatcctaaaa ccggggctgt cagagggctt gttggtcgtg tcaatagtac agaaaaccag
    12661 ccctttagaa gctttaacta tgctactcaa gccaagcgca gccctgcttc cacgatcaag
    12721 ccactagttg tttatactcc tgctgttgca gcaggctggt cgctggagca cgaactgcca
    12781 aacagcgttc aggattttgg cggctatcag ccgcataatt atgggaatta cgaatcagaa
    12841 acagttccta tgtatcaggc tttggctaat tcctacaata ttcctgctgt ttcaattctg
    12901 gatcagttgg gggtggataa ggcctttagc tatggtgaaa aatttggttt gaagatgagt
    12961 gataccaaaa aggagctggg agtggctctt ggtagtggtg tcaccaccaa tccgcttgag
    13021 atggcacagg cctatgcagt ctttgccaat ggcggtgtca agcatattgc ccacctgatt
    13081 accagaattg aaaatgctaa gggcaaggtt atcaagacct ttacagacaa aaccaagcgg
    13141 gttatcagcc aatcagtggc tgataagatg actagcatga tgcttggaac cttttccaat
    13201 ggtacagctg ttaatgccaa tgtctatggc tatactctgg ctggtaaaac agggactaca
    13261 gaaactgact ttaacccaga tctgtccggt gatcagtggg tcattggcta cacgccagac
    13321 gttgtcatca gtcaatgggt cggcttcaat caaaccgatg agcatcatta tttatcagat
    13381 tcaagcgcgg gcactgcctc agcaattttt agcacacaag cttcctatat attgccatat
    13441 accaaaggaa gtcaattcaa gatcgataac gcttacgctc aaaacggtat ttcagcggtg
    13501 tatgggatta atgagaccaa tacgcaagcg ggtattgatt ctcaatccat cattgatagt
    13561 cttagaaagt cagccgagga agcctcaaaa tccatctcag aggcagttga tcagtctggt
    13621 cttagagaaa aggcgcaaag tatctggaag agtattgttg actactttag atagcttgcg
    13681 aaaatatcta aatcgtgtta gaataatcac tacggaggcg ttatggcaca gaaaaaagca
    13741 agcctagcgt gtgtagaatg tggcagccgc aattattcta tcgggattag cagcacgcct
    13801 agaccaacac gactagaagt caataagttt tgcaaatatt gtaaagcata caccttacac
    13861 aaagaaacac gttagaggag agcctgatgg gattcattag tgggattttt aagcttttaa
    13921 gggatacaac ttggccggat cgtaagcagc gctggaagga ctttatttct gtccttgagt
    13981 atacagcatt ctttacggta atcatcttta tctttgacca gttgctatca aaaggcattt
    14041 tatcattgat taatttattc taagtcattg caatgatgag acctgttatg attaaaattg
    14101 cttggaaaag cctaggctga aacaatcgtt tcggcctttt tgagtgcgat gggcaggttg
    14161 tactctgata gatgcaagac caatagacca cctactatgc gggtgcgtaa aggggtgata
    14221 gctgccgaca gtcaagggct atagcaagta gaaaggctgg gcagctcagc tgatccgctg
    14281 ttatgactaa aggcattgac cagaaaggtt cgttgacagc caacaaagtg ctcttaccct
    14341 gctatgaggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14401 taacagcaat gcaaaggcca acagaggctt ttttataatg aaaggaagta acatgttaga
    14461 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaggtaaa
    14521 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14581 gattcctacc caaacggtaa atgttgaaaa aaatggccag gtcaaagagg ttgaagaaaa
    14641 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14701 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14761 ccctctactt gaagaggaga ttcgcgcaat cctgttgtca atggggcaaa ctgttgatgt
    14821 ctttgatacg aatatcaaag aaggtgatat ggttcaaatc attgatgggg cctttatcgg
    14881 acaagagggg cgtgttgtag agattgaaaa caacaaggtc aagctcatgc tcaatatgtt
    14941 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctaata
    15001 gactcttaaa acgattattc ataccatata aaaataaaag gctggcatcg gctttctcag
    15061 ataccgatgt taggtctttt tttgttggtc tcctacgacc aagactcaaa ttaaccagac
    15121 cccaaaaaga gtcatttttc cttcgctttt aagtctctaa ctgatcgccc tagcttattt
    15181 ttaatccagt aatcgcaaca ggtcaagagt taaacgatat cgtgc
//
LOCUS       DARYSY010000049        14887 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYSY010000049 DARYSY010000000
VERSION     DARYSY010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14887
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            231..488
                     /locus_tag="TVR04_001521"
     CDS             231..488
                     /locus_tag="TVR04_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1270198.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            525..1256
                     /locus_tag="TVR04_001522"
     CDS             525..1256
                     /locus_tag="TVR04_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270199.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVLVNGQLLSEHRDAIKKQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            1261..2889
                     /locus_tag="TVR04_001523"
     CDS             1261..2889
                     /locus_tag="TVR04_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270200.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRKLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPLSGQALLNFWLPLLLVMLMLYGLVRRVMPAYYR
                     ETLYVGGNAKKAAVARKAAAADRQQSLQRLLIKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITYEYFGIALLVGVLLGSVCTVPTSFVGVGISLEKENFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYAFIGLFVLGFHPVIVLFFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWLQRSFWKNLNKM"
     gene            complement(3476..4594)
                     /locus_tag="TVR04_001524"
     CDS             complement(3476..4594)
                     /locus_tag="TVR04_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270201.1"
                     /translation="MLKLSKTTKIAMSFLIVFCGIVFVAQRRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGKVTYLPAADYAFTSSGVSSDYYFTSTANTDDSFIAVFDPKLKEIDK
                     HIFDTSIIASDFSVDGDDIYLLGTDVKTKDNYPTYLYTLSIKNGQLAMKNKELLYEQP
                     ESTYFFHDSIVKEKQLYTASSGYRNNVTKERTVLGQVFHYDMQSGQKHFFDLTEIAPV
                     NIFDLGHDTLAIEHEKNEAGKIGFSLFHLNDKTSTFIDLSQFGLSIESDYLKDVKQID
                     ENTLLILAGHTLIGYHINDHQAIFNKQVSDDAFHIWVK"
     gene            5203..6021
                     /gene="proB"
                     /locus_tag="TVR04_001525"
     CDS             5203..6021
                     /gene="proB"
                     /locus_tag="TVR04_001525"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1270202.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVIFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDACLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            6021..7268
                     /locus_tag="TVR04_001526"
     CDS             6021..7268
                     /locus_tag="TVR04_001526"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1270203.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEIMLDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSIDAFSLAFKTNNAIILRGGKDALYSNMALVKLV
                     RNALEASAITPDAVQLIEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            7288..7704
                     /locus_tag="TVR04_001527"
     CDS             7288..7704
                     /locus_tag="TVR04_001527"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270204.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLEDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            7807..8757
                     /gene="rsmH"
                     /locus_tag="TVR04_001528"
     CDS             7807..8757
                     /gene="rsmH"
                     /locus_tag="TVR04_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1270205.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQRAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTELDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQQAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            8761..9084
                     /gene="ftsL"
                     /locus_tag="TVR04_001529"
     CDS             8761..9084
                     /gene="ftsL"
                     /locus_tag="TVR04_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1270206.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            9088..11343
                     /locus_tag="TVR04_001530"
     CDS             9088..11343
                     /locus_tag="TVR04_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1270207.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKINGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYRLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            11345..12352
                     /locus_tag="TVR04_001531"
     CDS             11345..12352
                     /locus_tag="TVR04_001531"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1270208.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTLQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            12435..13778
                     /locus_tag="TVR04_001532"
     CDS             12435..13778
                     /locus_tag="TVR04_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1270209.1"
                     /translation="MSFHDYHFKHYIQKALDELGFVEPTEVQQRLISIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(14419..14874)
                     /locus_tag="TVR04_001533"
     CDS             complement(14419..14874)
                     /locus_tag="TVR04_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270210.1"
                     /translation="MKKVIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
BASE COUNT         4157 a         2811 c         3501 g         4418 t
ORIGIN      
        1 acgattatcg tctgattttg ttacctatgg ctaaaaataa gaagcacaac tgactgcccg
       61 tattgcccta aaaaaggaac aaaagtaagc gccatcatcg ttggtatatc tgcttttgtg
      121 aaaagagaca aatatggcga taggatattg acaaaaagcc taataaagat tatgattgaa
      181 gtgttaacta gttgtattag cgtaaacgta caaaattaga gggaggccct atggaaaagg
      241 aacagcagcg cttatacgat gtcatcaaac aggcctacga ttacccagaa aatcgtgcta
      301 atagccattt agccagatta ttgctgtcag cttctaacca attaatcaaa aacagtaatc
      361 cgctgacgat tgcagagcag ctaaatcaag cgcttgatga ttacttacag gccaatgatt
      421 tgttgttgcc taagtccttg tgtggcttta agcagtcgct tgacgcttat ttattagaaa
      481 aaggctgacc agcatgagcg gctggtttag gataggagag agttatgata gaatttagac
      541 atgtttcaaa gctatacggt gacaaggagg ccttgagtga tgtaagcctc acgattaagg
      601 acggtgaaat ctttggtctc attggtcaca atggggctgg caagacgaca acaatcagta
      661 tcctgacctc tattatcgaa gcaagctatg gcgaggtctt ggtcaatggt cagctgctaa
      721 gtgagcatcg tgacgccatc aaaaagcaaa tcggctatgt gcctgattca ccggatattt
      781 tcttaaacct gacagcctat gaatattggc agtttcttgc taagatttat ggcgtcagtg
      841 aggcggatac caaagctcgg attgaggagc tgacgcagtt atttgagctg acgcaggaga
      901 tgcacaacac gattgataac ttttcacatg gtatgcgtca aaaggtcatt gtgattggtg
      961 ctttgatctc caaccctagt atctggatcc ttgatgagcc cttgactgga ctggatcctc
     1021 aggcttcatt tgatctaaag gaaatgatga aagagcatgc tgcttctggt aatacggttc
     1081 ttttttcaac gcatgtcttg tcggttgctg agcagctgtg tgaccggatt gggattttga
     1141 aaaaggggaa attgattttt gttgggacag ttgagcagct aaaggctgat tatcctgata
     1201 aggatctgga gactatttac cttgaattgg caggacgtca agcacaggag gcatagtggt
     1261 atgaattggt caactatttg ggaattagtc aagattaata tcctttattc caatcctcag
     1321 tccctgacag ctttaaagaa aaagcaagaa aaggctccca aagagaactt caaggcctac
     1381 aagagtatga tcagacagca agccttgatg attgctctgt ttttagtcat ttacatcttt
     1441 atgtttatgg gtgttgattt tagccaatat ccgggactgt tgtcacttta tattgctatt
     1501 ttctttgtca tggcaactgt caatgccttt acggcaatgt atgcggtctt ttatgagagt
     1561 aatgacgtta agctctatgt tcatttgccc ataaggtctg aggagctttt cattgctaag
     1621 ctgatttcct cattaggtat gggatccata tttttaatgc cactgctaag ccttttcgtg
     1681 attgcctact ggcagatcat tggaaatgct ttggcgattg tgctagcgtt tatcctgttt
     1741 gtggtgctat ttgtcagctc gattgttttt gctctgtatc tcaatgcttg gattggcagg
     1801 attattctga ggagcagtaa gcgcaagctg atttcagcgg ttttgatgtt tgcttctacc
     1861 tttggtgctc taggcttgat tgtatttctc aatatgacta acaatcagcg aatgatggct
     1921 gatcaagcct tttcagatcg ccctttgatt ccttatttta ggggcagcta tgatgttgtt
     1981 gtggcaccgc tttctggtca ggctctgctt aatttttggc ttcccttgct tttggtcatg
     2041 ctgatgctgt atggtcttgt tagacgggtc atgccggctt attacagaga gaccctctat
     2101 gttggtggaa atgctaaaaa agcagcagtg gcgcgtaagg cagctgcagc tgatcgtcag
     2161 caaagcctac agcgattgtt gataaagcac catcttgcaa cactgcaaaa tgcgacgcta
     2221 ttgacacaga cttatctgat gcctttgatt tatgtgatga tctttatcac tcctagtgtg
     2281 acaagcggtg cacaattttc aagctacatt acctatgagt actttggtat tgcgctttta
     2341 gtgggggtgc tcttgggaag tgtgtgtact gtgccgacca gctttgttgg tgttgggatc
     2401 tctcttgaaa aggaaaattt cacctttatt aagaccctac ccattagctt aaagggcttt
     2461 ttgcttaaca aatttcgctt gctgataggt ctgcaaatcc ttgctccact ggtggtttat
     2521 gcctttattg ggttgtttgt attaggcttt caccccgtta ttgtcctatt cttttcatta
     2581 ggttttgtct tgatgggaat catacaaggg caattgatgt ttaggcgtga ttatcgcatg
     2641 ctagatctga aatggcaaga cgtcacccag cttttcacca gaggaaatag ccaatggttt
     2701 atgcttgggc tgatgtttgg cgacttaatt gttggtggct ttttgattgt tttagcaatt
     2761 atgtgtgcta ccattagtca gcagcctctt cttgtgagca ttgctgtgag ccttattctt
     2821 ctgagctgct tgctctttgc tcagctctgg cttcaaagaa gcttttggaa aaatctgaat
     2881 aagatgtaaa tagctctggg gtattaattc tccagattgg ccaaggtaag atgtgacgaa
     2941 gttttggttc tagctcaaat agtgagagta attgcagtaa ctatatgtta aaagctagag
     3001 cagctattga aaaaagaaag caaaaagctt tagcaagcta gcagtgccct gtcgtagcag
     3061 cttgtggaac atcaagttca agctcctaaa gctgttagtg atgttgctca gcaaatagct
     3121 ttgggagcct cacgaaaaag ctaactcagc tttagtagct attagcttta ggtcaacagt
     3181 aatgcgccaa atcattttca aaaagggctt ccatgacgtt ttggctggag tgacattctg
     3241 ataaccaatc acaagcatgc tagctttatc ccgtcttaat ggcggtttca aatactacta
     3301 atttaggcta gcttcttgga aaaagctagc ctaagtgttt taatcatgcc cacccgtttg
     3361 acgggtgggc atgatttgtc acgcacctta cggagcgtga cggactaaaa gtcacataac
     3421 taaaaaatca aggtacaggt ccttgatttt ttgttgtttt cagttaactg actagctatt
     3481 ttacccatat atgaaaggca tcatcactca cttgtttgtt aaagatagct tgatggtcat
     3541 tgatatggta tccgattaat gtatgaccag ctaatattaa tagggtgttc tcgtcaattt
     3601 gtttgacatc ttttaagtag tcactttcaa tggataaacc aaattgagat aagtcaataa
     3661 aagtagacgt tttatcattg aggtgaaaca ggctaaaccc aatttttcca gcttcatttt
     3721 tctcatgctc tattgccagt gtatcgtgac ccaaatcaaa aatgttgact ggagcaatct
     3781 cagtgagatc gaaaaaatgt ttttgacctg actgcatatc ataatggaaa acctgcccta
     3841 aaacggttct ctccttggta acattgtttc gatagccgct tgaggcggta tagagctgct
     3901 tttctttgac aatgctatca tggaaaaagt aagtggattc aggctgttca tagagcagct
     3961 ctttgttttt catagctaat tgcccatttt tgatagatag cgtatataag taggttgggt
     4021 agttatcctt ggttttcacg tctgttccta agaggtaaat gtcgtctcca tcaactgaaa
     4081 aatcgctagc aatgatagaa gtatcaaaga tatgcttatc aatttctttg agcttgggat
     4141 caaaaacagc aataaaacta tcatcggtat ttgctgtaga agtgaaataa taatcagatg
     4201 atactccgga ggaagtaaag gcataatcag ctgctgggag atatgttacc ttgccttttt
     4261 gaaaatcaag tgcgataagc cttcctattg cccccaaagg tggcccctcc tcggaaaaga
     4321 ccagataacg atttgaaagc tctgctcgtt taaccacttg attgatctga cctttgacca
     4381 cttcgagctt agcgtcagaa attttttgcg gctgctcgtt tgtcaactga taaccttcaa
     4441 tattgtggta accgactata tagaaatctg catctggcct tacggtaaat gattggtctg
     4501 atgaaccgaa tcgtctttga gcgacgaaaa ctataccgca aaagacaatt aaaaatgaca
     4561 tagctatttt ggttgttttt gatagtttaa gcatagtgat ttattcctat aactaattaa
     4621 ttgctttaga tgactgacaa gttctgttgt cctgagcacc ctaaactagt tgaacagttg
     4681 aggcttcctg attgtttggt attccaaaac atttaaatgg tacagctttc ctacctgaat
     4741 tccagcccat tgatctgcgt tccagtcttg ttgaacactg gtagcctttg cgccaatgtg
     4801 ccagacagta tgcctgtgac ttgttcttgc gacttctgaa acgtgttctt tctgtcaggt
     4861 attgcgcttt acagcaaggt ctggccctta cgtagtaaat atagctgttt gcgctttcat
     4921 tttatcctat tgtgcgtttt tgtcaatagc tttagtgttg gtatatggtc attaaaaatg
     4981 acaggacaat gcaggaggat cagacttaaa cttacaatag gataaagcgt agcgtggtat
     5041 gtggtgtcac aaaggaaatc ctgcttggag tggctatcag gtgggtttta tatcttaggt
     5101 gaatgggtag ccagtgatcc ttttttgtca agctgatagg ctgattgatt ttgtcttcaa
     5161 tctgccagtc ctctgagctg ttttttatgc tataatccta atatgatgaa acgacaattt
     5221 gaagatgtaa agcgtattgt aattaaaatt ggaaccagct cactggttct tgcgaacggg
     5281 aagattaact tagaaaagat cgatcattta gcctttgtga tttcaagctt aatgaataag
     5341 ggaaaagagg ttattttggt ttcctctggc gccatgggct ttgggcttga tctgttgaaa
     5401 atggccaaaa gaccaagtca gcttgccaag cagcaggctg tctcaagcgt agggcaggtt
     5461 gctatgatga gcctttattc gcaaattttt gctcactatc agacgacggt gtctcagatt
     5521 ttattgacac gtgatgtggt tatttttcca gaaagtctag caaatgttac caatgccttt
     5581 gagagcttga ttagcctagg tattgttccg attgtcaacg aaaatgatgc tgttagcgtt
     5641 gatgagatgg atcattcaac aaaatttgga gacaatgacc gcttatcagc tattgtggct
     5701 cgtattacaa gggctgatct gctgattatg ctgtcagata ttgatggtct ttttgataaa
     5761 aacccgacca tctatgagga tgcttgcttg aggagtcatg tgacagagat cacagaggac
     5821 attatagcct cagcaggcgg tgcaggcagc aggtttggaa ctggtggcat gctaagtaag
     5881 atccaatcag cccagatgat gtttgagcat caagggcaga tgattttgat gaatggtgcc
     5941 aaccctagag acattttaag ggtcttggag ggagaaaagc taggcacctg gtttaaacag
     6001 atagaaagag gtgacgcgtg atgacaatag aacagctagg acaaagggct aaggcagcta
     6061 gtagagcctt ggtatcctta acaacgaagg ataaaaatca atttcttgcc tttttggctg
     6121 aggaattggt ggcccagacg gatatgattt tgacagaaaa tgccaaggat ctggctaagg
     6181 cggctgagca tgggatttca gagattatgc ttgatcgctt gcgcctgaca gcagatcgta
     6241 tccatgcgat ggctcagggc gtcagacagg tggcagactt ggctgatccc attggcgagg
     6301 tgattaaggg ctatacaaat ctggacggtc ttaaaatcac ccaaaagcgt gtgcctttag
     6361 gcgttattgc aatgattttc gaaagccgcc ctaatgtttc tattgacgcc ttcagcttag
     6421 cctttaagac caataatgcc attattctta gaggtggcaa agatgctctc tactctaata
     6481 tggctttggt caagcttgtt agaaacgcct tagaggcgtc agctattacg ccagatgctg
     6541 tccagctgat tgaggatacc tctcatgctg tagctgagga attgatgcag gcaacggatt
     6601 atattgatgt tttgatacct cgtggtggtg ccagattaat tcaaacggtc aaggaaaagg
     6661 ctaaggtgcc agtcattgag acgggggttg gcaatgttca catttatgtt gatgaagcag
     6721 ccgacctaga gatggctgtt aaggttgtga ttaatgctaa gacgcaaagg ccaagcgtct
     6781 gcaatgctgc agaaagcctg attattcatg agaaggtagg agcgaccttt attcccatgc
     6841 ttgaagcagc catcagtaag gttcagcagg tggaatggcg agcagatgag caggcaaaag
     6901 ccttgtttag caaggctgta ttagccacag aggaagatta tgcggctgaa tttttggatt
     6961 atatcatgtc tgttcatctg gtttcttccc ttgatgaagc tatttcttgg attaatcagt
     7021 ataccagtca tcattcagaa gccatcatca cagctaatat caatgctgca gagcgttttc
     7081 aggatctggt tgactcggcg gctgtttatg tgaatgcctc gacacgcttt acagatggct
     7141 ttgtctttgg tctaggagca gaaattggca tttccacaca aaaaatgcat gctcgtggcc
     7201 cgatgggact tgaggccttg accagcagta aatacctgat caatggaaat ggccagattc
     7261 ggagctagct gctaaggagg taggcttatg acaagggatc taaagaagca agaaaccata
     7321 cgagacctaa agacattagc ttttaagctt gagtctgtca ttgaggcatt gaaagagctt
     7381 aagaggtggg gattttttga tttgttcgac aatgggatac taacaagttg ggtaaaaagg
     7441 caaaaaatca gtgctattaa tgagagccta gaggacgtga gaaatctggt ctgtaggtat
     7501 caaaaggagc tgaaggttag tgagttgcgc ttgccttcta gcttatctca tacaagacag
     7561 gataagatct ttgatatttg gctagataat tcggtgacag attttcgggt gttaaaggag
     7621 accaagcagg tgctcgaatc ggctgagctg ctgtatgagg ctgtgcagca agctcttagt
     7681 catcttgatg tcaaggatag ctaagtcaaa aaaagtaaga taaagatgga ctttcttagg
     7741 ccttgaaagc ccttttctct tactttttga tttataaacc ctttgaagta tggtacaatt
     7801 agagctatga caaacgaatt tcatcatgta actgtacttc ttcatgaagc tgttgatatg
     7861 ctggatatta agccagatgg tatttatgta gatgcgaccc ttggtggctc tgggcactca
     7921 gcttatttgc tgtctctgct tggtgataag gggcacttgt attgctttga tcaggaccaa
     7981 agggctattg atcacgcgca ggagcagctc aagccctata ttgacaaggg acaggtgacc
     8041 tttattaagg acaattttag acaccttaag gcacgcttgc tggagcatgg ggttacagag
     8101 cttgatggga ttttgtatga tttaggggtt tctagtccgc agttagatga gagagagcgt
     8161 ggcttttctt acaagcagga cgctcccttg gacatgcgaa tggatagcca ggcggctttg
     8221 acagcctatg aggttgtcaa tacctatgat ttcaatgact tagttcggat cttttttaaa
     8281 tatggtgagg ataagttctc aaagcagatt gctcgtaaga ttgagcaggc gagagccatt
     8341 aagccaatca gcaccaccac agagctggca gcattgatca aatcagctaa gccagccaag
     8401 gagctcaaga aaaaaggaca cccggccaag caaatctttc aggctattcg tattgaggtc
     8461 aatgatgagc ttggtgctgc tgatgcgtct atccagcagg cgatagagct gctagccctt
     8521 gatggccgta tctcagtgat tacctttcat tctttggagg atcgtctgac aaagcacttg
     8581 tttaaagaag caagcacagc tgatgctcca aagggacttc cctttatacc tgatgagctc
     8641 aagcctaagc ttgaattggt ttcgcgtaag ccgattttac caagtcaaaa ggagctaatg
     8701 gctaacaata gggcacattc agccaagcta cgagtcgcaa gaaaagttcg gaaatagatt
     8761 atggttaatg aaaaaagaac tcaggcagtt tcaaaagcct tgcaaaaaag aattagaact
     8821 ttctcgaggg ttgagaaggc tttttatgct acgcttatcc tgacagcagt aacgatggct
     8881 gtaagcatta tttacctgca aagccgtaaa ttgcagctcc agcagcatat cactcagctc
     8941 aataggcaga tctcagataa aaggacagag cttaacaatg ccaagcaaga ggttaatgag
     9001 ctgtcgcgac gtgaccgcat tgttgatatt gctggcaaag cagggcttag taaccgaaat
     9061 gataacatta agaaggtcga gtaagctatg acaaaatggc aaagatattt tttagattat
     9121 gtggttcgtg atcgaaagac acctgttcag aatcgcttga gggtggggca aaacatgatg
     9181 ctcttaacca tcttcatttt cttcattttt atgattaatt ttatgatcat tatcgggacg
     9241 gatcagaaat ttggtgttaa gctatcagat ggagccaaaa aggtttatca agagacggtt
     9301 tctgttcagg ccaagcgagg cacgatttat gatcgcaatg gcacagctat cgctgtggac
     9361 tcgacgacct atagcattta tgccattctt gataagtcct ttgtgtcagc gactggcgag
     9421 aagctctttg ttcaaccgtc tcagtatgac aaggttgctc aaatcctcaa ggagcagctg
     9481 ggtatggagg aaaaggacgt tattaagcag cttaagcaaa aaggtctttt tcaggtttcc
     9541 tttggtccgt ctggctcagg tatttcttat agcacgatga caacgatcca aaaggctatg
     9601 gaggcagcta aaatcaatgg gatcgcattt tcagcaagtc ctagccgtat gtatccaaat
     9661 gggacctttg cttcagagct gattggtctt gcttcacttg aggaaaacaa ggaggacggt
     9721 accaagagcc tagttggaaa gatgggcatg gaggcggcct ttgatagcat cttatctggg
     9781 gaagatggaa tcatcactta tcaaaaggat agaaacggta ataccctgct tggaacagga
     9841 aagacagtga aaaagccagt tgatggtaag gacgtttata ccaccctgtc agagcctatt
     9901 caaacctttc tagaaacgca aatggacgtc tttcagtcga aggcgcaagg agagcttgct
     9961 agtgctactc tagtaaatgc taagactggt gaaatcttag cgactactca aagaccaacc
    10021 tataatgcag acaccttgga ggggctaaac agcaaaagct atagctggca aaatattctc
    10081 catcaggggc agtttgagcc cggctcaacc atgaaggtta tgactttggc agctgctatt
    10141 gatgagaagg tctttaatcc tgatgagacc tttagcaatg cgaatggctt aaccattgct
    10201 gatgctacta ttcaggactg ggcgattaac gaagggattt ctacagggca gtatatgacc
    10261 tatgctcaag gcttttcgtt ttcaagtaac gttggcatga ccaagctaga gcaaaaaatg
    10321 ggaaatgaca aatggatgaa ctacctaact aaattccgtt ttggattccg gacacgcttt
    10381 ggcttggaaa atgaagaccc aggtattttc ccttctgata atattgttac ccaagcaatg
    10441 agcgcttttg gtcaggggat ttcggtgacg caaattcaaa tgcttagagc ctttacagcc
    10501 atctctaatg acggtgtgat gctagagcct caatttgtta gtcgcattta tgacccaaat
    10561 acagatactt accgggtgtc agacaaggag attgtcggaa agccggtgtc ccaaaaggct
    10621 gccagtgaaa cacgaaaata catgattaac gttgggactg acccacaatt tgggaccctc
    10681 catttgaaat catcaggtcc agtggttaag gttggtcaat taccagttgc tgtcaagtca
    10741 gggactgcgc agattgcgac taaggacggt acaggttatt tagatggtgg cttgacaaac
    10801 tatatttatt cggtggttgc tatggtgcca gctgatgagc ctgattttct gatgtatgtc
    10861 acactgaagc acccagagca ttgggcaatg gtgttttggc aggatattat caaccctgtt
    10921 ttagaggaag cctatttgat gaaggatact ttagacaagc cggttgctgt agataccagt
    10981 cacgaggcta cttatcggtt gcctgatatt gttggccaag atacaggaaa atcagctgat
    11041 gagctacgca gaaatctggt tcaccctatt gtccttggca atggcagcaa gattaaaaag
    11101 gtatctaaaa aggcagggac caatctagct gctaaccaac agctcctgat tttatcaaat
    11161 cattttgatg agatgcctga tatgtacggc tggactaagg ctaatgtggc tacctttgct
    11221 aaatggactg gcattgatat caagtacaag ggatcaagct cgggacgtgt cgttaaacag
    11281 agcgttgatg tcggaaaagc gctcaaaaaa gtcaaaaaaa ttaccataac tttaggagat
    11341 taacatgttt ttaaccattc tagcaggtct gatagccttt gctgtgactg cccttgccat
    11401 gcctcacttt ataaggcttt accagttgaa aaaaattggg gggcagcaga tgcatgagga
    11461 cgttaagcag catttggcta aggctggaac acctacaatg ggaggaacag tttttcttct
    11521 tgttgccaca agcttatcct ttgtgtttgc tttagtctat tttcgagatg gacaaagcct
    11581 aggcttgatt tcggggatct tgttgattgt attgatttac gggatcatag gctttttaga
    11641 tgatttctta aagatcttca agcaggttaa tgaaggcctt actgccaagc aaaaattcac
    11701 gcttcagatt gttggaggcc tggtctttta tgtgatacac gtcatgccaa gtggtattga
    11761 tgcgattaat gtctttggtt atcattggca tttgggcttt ttgtacctat gctttgttct
    11821 tttttgggtg gttggctttt caaatgcagt caacctgaca gacggtattg atggtctggc
    11881 ctcggtatct gttgtgatta gcctgctggc ctatggtgtt atcgcttatg ctcagggaca
    11941 atttgatgtt ttgctcttga taggtatcat ggttggtgcc ttgctggcct ttttcttgtt
    12001 caaccataag ccggccaaaa tttttatggg tgatgttgga agcttagcct taggagcaat
    12061 gctagcagcg atttctattg cgcttcgtca ggaatggacc ttgctggtta ttgggattgt
    12121 ctatgttctt gagacaagct cagtcatgct tcaggttact tactttaaat acaccaagaa
    12181 aaaatatggt gaaggccgtc gtatttttag gatgactcct tttcatcatc atctggaatt
    12241 aggcggccta tccggtaaag cagccaagtg gtctgaatgg aaggttgatg ccttcttatg
    12301 ggctcttggt cttgtagcca gtctcattgt tttagcgatt ctttatttgt aagcagctgg
    12361 ggcagtgctt gaggcaccgc cttttgctca tctcaagcac taataatatt atcagaaaga
    12421 aaacgaggta aataatgtca tttcacgatt atcactttaa gcattatatt caaaaggcct
    12481 tagatgagct tggctttgta gagccaacag aggttcagca gcgtcttatc tcgattgtca
    12541 gtacaggacg agacttagtg ggtgagtcaa agacaggctc aggaaagacg catacctttt
    12601 tgctgcctat ttttgaaaag ctcaaggagg aaaaagaaga ggttcaagct gtcattacag
    12661 cacctagccg ggaactagca acacagattt ttgaggccag caggcaaatt gctaagcatt
    12721 ctaagcagga gattcgtatt gctaattacg ttggagggac agacaagcag cgtcagcttg
    12781 acaagttaaa gcttagtcag ccccagcttg tcattggaac gccaggtcgt atctatgatc
    12841 tagtcaagtc aggagattta gccattcata aggcctctac ctttgttgtt gatgaggctg
    12901 atatgacaat ggatatgggc tttttaagca ctgtggataa gattgcttca gcactgccaa
    12961 agactatcca aatacttgta ttttcagcaa ccattccaca aaagctacaa ccctttttaa
    13021 ggaagtattt gaccaatcct gtcattgaac agatcaagac agaaaccgtt attgcagata
    13081 cgattgacaa ctggctgtta tcaaccaagg gacgcgataa aaatgagcaa attttggcga
    13141 ctctaaaggc tatccagcct tatctggcca tgctttttgt caataccaag gagagagctg
    13201 atgacttaca tgccttttta gcagctaatg gtatgaaggc agccaagctt catggaggta
    13261 ttcctcctag agagcgcaag cggatcatga atcaagtcaa aaacctggca tttgaataca
    13321 ttgtggcaac ggatttggcg gcgcgtggta ttgatattga gggggttagt catgtgatta
    13381 acgacgccat tcctcaagac ctatcctttt ttgtgcatcg tgtggggcgg acaggtagaa
    13441 acggcctgcc agggacagcc attacctttt atcagccaag tgatgattct gatatcaagg
    13501 agctggaaaa gctaggcatt acctttatac caaaggtttt aaaaaatggt gagtttcagg
    13561 atacttacga tcgtgatcgt cgccagaatc gtgaaaaagc ttatcagaaa ttagacactg
    13621 aaatgattgg cctggttaag aaaaaaaaga aaaaaattaa accgggctat aaaaagaaaa
    13681 ttcaatgggc agttgatgaa aagcggcgca agcagcgacg agcagaaaaa cgtgccaagg
    13741 gacgagcaga gcgtcagtcc agaaagcaaa gcttttaaga caggtgcttg gtaaagatca
    13801 tccgttcaag aaaaattaga tcaaaaagtt ttttagcgat cattctaagc tgatatgaac
    13861 agaatccttg atagagctga gtcaaggagt agggattagg tctaaaagct gtttagggat
    13921 tgttttttag gatttcaact ctgttcagtg tcccgtgtca aatggtcctg tcgttgcgtg
    13981 caaggatttc aatctacgct cccacaaaag gtgtgataaa agtattgtta catttgaaat
    14041 tgtcgaacct acttcaattg ttacagcaac tatctttgaa gcgtggcaac taaaaccagc
    14101 tattaacaac taaagccgca ccttttgctg tcagaatagt gattgaaatt aacgggttga
    14161 tacgctttga cacaccagcc ttaaattact tcctctgtgg gagtatggat tgaggtgtat
    14221 taatgtttgg agaggagctt gctcctcttt ttgcttgttc agctcaatgt ctctatgaag
    14281 gctatggttt tggttagatg gtaagcacta aaaaacctta taagcattga gcatgggtct
    14341 aaccatttca atgcctataa ggcttatgat tagctaatac tagctattat ataaagcagt
    14401 cggttaacta agctgcggtt acttattagc ctcataccag gctagcaccg cttcttgaag
    14461 ctctccgatg ctggtagatt ctggactaaa gatattgagc tctgagacgc cgtcaatacc
    14521 agtcttaaca ccgccatctc cctcataacc ttctaggata ctccaatacc ctccatcagg
    14581 atcggcaata atccttgaat ttttagtcag gtactcaccc tctccagcga aaatataatt
    14641 catgaggaag gtctctgtca gaatgccttc tcttttagcc tgagctaggt aagtaatcat
    14701 tttattaatg gttacattgt catgatactt aattactggt tgttttcttg actggataag
    14761 acgtgccatc tccttatgat ttaaatcaga ataatcagtg gagtagataa atcttgttga
    14821 taagcttaaa acagctactg ttaacaaagt aaccgatact attacctttt tcatagaaaa
    14881 cctcctc
//
LOCUS       DARYSY010000050        14859 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYSY010000050 DARYSY010000000
VERSION     DARYSY010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14859
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(433..2844)
                     /locus_tag="TVR04_001534"
     CDS             complement(433..2844)
                     /locus_tag="TVR04_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1270211.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGKHKALNSSSKDHSIAYVD
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVTHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELAAAQAYWNNKQGGKPSVIGGQPLPDQGYQPRPYDIPVNPI
                     HHPVGNLPSVGDPSLSFADKTFAELLDQLHGLDKKYRHVEEDGLIFEPTQVILANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGVTAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTDIQPKLAVEVSSLPMHAGNATYDTGT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPSKGQEPSAQDTAADGTEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLVLYDVTT
                     LQQIK"
     gene            complement(2859..3782)
                     /locus_tag="TVR04_001535"
     CDS             complement(2859..3782)
                     /locus_tag="TVR04_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1270212.1"
                     /translation="MKRKWLHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSEVAVFEASKTLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLT"
     gene            complement(4109..5656)
                     /locus_tag="TVR04_001536"
     CDS             complement(4109..5656)
                     /locus_tag="TVR04_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEL1270213.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANVNTYTTYARDNAVAATSQT
                     AEGFDFVATILASNGHVLEGKTVVLSDTTANPAKQVASAVSNSDGQAIFTQLPLNRNL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPIYSKNVIDITVRNQDSEPLEGQ
                     TVTLKTRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKASPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     ARTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSEPNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMLYDIVINGVKIPKKASTGSDVSGFLTKAQIRTGNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKPSSSRNVAPKEGKKETKALPRSGEAAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6301..7182)
                     /locus_tag="TVR04_001537"
     CDS             complement(6301..7182)
                     /locus_tag="TVR04_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1270214.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGDTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMREGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7347..8348)
                     /locus_tag="TVR04_001538"
     CDS             complement(7347..8348)
                     /locus_tag="TVR04_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1270215.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSIGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSAYQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMTKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPKYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8489..9661
                     /locus_tag="TVR04_001539"
     CDS             8489..9661
                     /locus_tag="TVR04_001539"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1270216.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLAFDKADLWANYPKGVLSFL
                     QKAGHPIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFELNVDRLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGANKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEKALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDRVDSFIETVEKTYTEVIGYAPAFYLAEIAQGARLLSRK"
     gene            9665..11149
                     /gene="galT"
                     /locus_tag="TVR04_001540"
     CDS             9665..11149
                     /gene="galT"
                     /locus_tag="TVR04_001540"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1270217.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11159..12169
                     /gene="galE"
                     /locus_tag="TVR04_001541"
     CDS             11159..12169
                     /gene="galE"
                     /locus_tag="TVR04_001541"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1270218.1"
                     /translation="MTVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHP
                     EAMFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMTDPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHELETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIITSAWAWHTKHPKGYDDKAS
                     GS"
     gene            12246..13289
                     /locus_tag="TVR04_001542"
     CDS             12246..13289
                     /locus_tag="TVR04_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1270219.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINANGVEAHLLTLGATLQAFLVP
                     NEKQPKNIILGHNRPSDYLKNPLCAGQTIGRVAGRIKGGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTADYLEVTFKRDILEADDRFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHSLHIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKPLYPAIVENNGFDTAFEIDQQAIGTTQPIAVLQDSISHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKVGLAREGIAMEAQTLPDAIHHNQFGDIILKEGDIK
                     SYTICLAYEHLPD"
     gene            13511..13726
                     /locus_tag="TVR04_001543"
     CDS             13511..13726
                     /locus_tag="TVR04_001543"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270220.1"
                     /translation="MSVSLSLKQSVASVIGYLKDKNSLIIFNKDANLKQKHRNQKFWC
                     LGYYGDTAGKNLKKIANYIPNHYRKIG"
     gene            14381..14503
                     /locus_tag="TVR04_001544"
     CDS             14381..14503
                     /locus_tag="TVR04_001544"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270221.1"
                     /translation="MIKDMKQQAFGFRNFKNFKVKIPNALNITKEETKFISSRA"
BASE COUNT         4239 a         3364 c         3031 g         4225 t
ORIGIN      
        1 ttgcgaatgg gtacaattgt acggctgcta acctttttcc taaccctttt agacaccaaa
       61 aaactcccct tatcgttttt agtgattgtt tttcactgtc cactttaaag gggaggtcta
      121 gctattaaag gctaggcggt tttgactgga ggactattag gtgtgaggtt aattggtaaa
      181 aagtctttct gtgctgccct ccttaggtca tatagacttt cttggaacca aaacccacat
      241 atagcctaca gagatccaat gctttaaaag ctatgaggtg ctaagctgct gatcaagtca
      301 gcttctctga ctgttgctgc aagcaaaagc ctactaagcg atcttaggct gtgaggcgta
      361 agaacaggtc atcataccaa tagctttttg gggataagct atgatttgta tgccttagct
      421 attttatagt gtttatttga tttgttgcaa tgttgtcaca tcataaagca ctaggtgtcc
      481 tttttggtca tagaatttga caccctctgg cacgaaaata agatactccg gtttaatgcc
      541 tgctatttca gctaactgat tgatctgacg ttcaagagtt gcccgatcta aaccataatt
      601 aggaatatcg tcaaataaag acttggtctg ctctgtgcca tctgcggcag tatcttgcgc
      661 tgacggttcc tggcctttgc ttggcttaat agtgctttca gctgcgtctg aggtcttatt
      721 gcctaataat tcttgaacct tttgccattc atcatgagat aactcatctt tagtaatggt
      781 tcttaaagag cgtccaccaa ctctaggaat gctaaaggaa tcattacgcc aaacaaaggt
      841 tccttcagca agaacgtcct taggatcaaa aatatagcca tctggagctg cgtaccgacc
      901 tgccttgata gctgcttgga cctcttcggc agagtgaata atttgccagt tttccattga
      961 agtacgttga tcagctggtg tgacattagc aatgactcct ccagcttcat catgatttgg
     1021 gttagaccaa acatcaggac gagtattagg gtgctgcatg acatatttga tggttgcaat
     1081 ctgatcctta gttagccatg aataaggtac aacatggata tgatcgatgt gaggaatgac
     1141 aaaagatgtc cctgtatcat aggttgcatt gccggcgtgc atcggtaggc tagatacctc
     1201 tacagctagc tttggttgaa tgtctgtatc aacaatgtca taaatatagt gttgcttatc
     1261 cttaagcatg agctcttgct ctgcaaaggc aatttgtgtt aggtctaaat gctcacgatc
     1321 atagaaatac tctttaccat cttttgtcat catgtaacca accttaccgc cattggttac
     1381 cttgcgactg acatgcttag cgtcaaagga catgtctttg ccgtctgatt gaactaatgc
     1441 ccttgcaatc tcatctgctt gaccatgctc ctgcaaccat tgtgcaacct gatcaagctc
     1501 ctcttgctct agctcaccaa agcccatgta atggaaatgc tcctcatgct tagctgtgac
     1561 acccgcctta tcaacagagg aaatagatgc cttactaaag acataatggt cactcgtgtc
     1621 ataaggcttg ccatctaagc ctttgccata agccttaatc tggtgaccaa ggaattgatg
     1681 tgtaacctct tttgcagtct ggtcttgagt agctggcttt ggcttagcta ttggactgcc
     1741 ctgtgtttga cctgctagat aacgatcagc taaggttatt tcaagggctg ataattgctc
     1801 acgaggaata atatggtagt gatctccatg agggataaca tagccaaagg cattggcaag
     1861 gatcacctga gttggctcaa aaatgagacc atcttcctcg acgtgcctgt attttttatc
     1921 caagccatgc aattgatcca gcaattctgc aaaggtttta tctgcaaatg acaggcttgg
     1981 atctcctact gacggcaaat tcccaactgg gtggtgaatc gggttaacag gaatatcata
     2041 tggtctaggt tgatatcctt gatctggtaa aggctgaccg ccaataacac ttggttttcc
     2101 gccttgcttg ttattccaat aggcctgcgc tgctgctagc tcacttgggg ataagtcctt
     2161 tttagggata tagtggaagt gactgccatg gggcactaaa aaggcatctc ccatgtctcc
     2221 aataacatct gtcgggctaa agatatagcc atcatcagtt gtatagcgtc cttgacttct
     2281 tgcttcgtta acagctgcca cctctgcctt actcaagtgg gtaaccttgg ccaagccttt
     2341 ttccttagct tcctttgttc ccttttcaac ctgctcagca atttgctgct tggtacgaat
     2401 atttttacgc ttgcttcctg gctttagata aacataatac ttgccatcaa ccttgataat
     2461 atagccatct agaatctcgt taacaacatc agactgttta aactgataat tggggtccgt
     2521 cattaatagc tcttcactaa gaatagcatc ataaggaacc ttaccattgt agaaatggaa
     2581 atgatcacca tgtgaggtta catagccttg atctgtgatt ttaacaacaa tttgctctgc
     2641 agagattccc tcttctgcac tgatttgatc cattgttttt tctttaggta gagctttttt
     2701 accatccttt gaatcgacat aggcaatgct atgatcttta gacgaggaat ttagagcctt
     2761 atgctttcca aactgatatg aagcagcatt agtagccaat aaaatggcca cagctgatcc
     2821 taaaacaata tgcttctttt tcacgttttc atctcccttt atgttaagct ttggtaaaga
     2881 gcttccaagt tagctctcaa attatctaga taggacttgt tatttttagg cgcggcctct
     2941 agtggactga gcagcttgac ctttgctccg gctgttttag ctatcgcctt agcaatttta
     3001 ggattaacat tgtcttctgc aaaaatcgtt tttaccttat actctttaac aaagtcttga
     3061 atttcagtta gttggcgcgg agtaggctct tgctctggcg aaataccaga aatacctaac
     3121 tgcttcaagc caaagcgctt tgctagataa gaaaaggctg tgtgctgtgt gacaaaggtt
     3181 ttagatgatg tctttttaaa ctttttagtg tactcatcag ccagctcttt tgcttccttt
     3241 tggaatgctt gagcattctc agtgtaaatg gcctcatgct taggatctaa acgactgagc
     3301 tccttagcaa tagcgagtgc ttcttcacct gctaaaatag gatctgtcca ggtatgagga
     3361 tcatacaggg tagcagggtc aatgccatct gtcacctcaa tatcctctaa accagtcaca
     3421 cgatccaagg ttaaggtttt ggaagcttca aaaacagcaa cctctgactt cttcagatta
     3481 ggatccaaat catcagccca ggcctctagg gtgtgagagt gataaacaaa taaatcagca
     3541 tcgtaaatgg cagcaacgtc atttacagat ggctcaaagg aatgaatccc tgcccctgac
     3601 tgaatcatcc gaacatcgtt tagctcacca gataccgcct ttgtcatggc gtaaatagga
     3661 taaaagctag tgacgatcgt catgcctctt gactgcttgc tttgctcctt gggcttgcta
     3721 caggcaacaa gacctgaaaa aagagcaagc aacagtgtta aatgtagcca ttttcttttc
     3781 atataatctc cttcgctcat taaccagtta tgaaccggtt aattttaaca gctttagatg
     3841 tatttgtcaa attttttaat aaaaaataaa agccattaaa acgatggctt aatcagcccc
     3901 taacctgctt aacctttata agaagccata gctctatgat aaactgtggt ctgtgacgca
     3961 tgacctcact gtctgttatc ttactgttgc atgatacgtt taaaaaagat ttagccttct
     4021 ttttttagat tgtagaacgg cgctgaacaa tcacttaacc gtcaaaaaaa cgccttgata
     4081 gttgcaagac gtttttactt atttggtttt agctagagcg acgttttgtc acaagaccga
     4141 tgacagctgc aaggcctatt aatagaactc ccatgaacgc taccatcgga gctgctgctt
     4201 caccagatct tggcaaagcc ttagtctctt ttttgccttc tttaggggct acattgcggc
     4261 ttgatgaggg cttggtttct ggcttagcga cattcttatc tttttcaggg tcctttggct
     4321 ccttgcctaa aggctttgta tctttagaat ggcgctcaga ctcgctgagc ttattaccag
     4381 ttctgatttg agctttggtt aaaaagccgc tgacatcact accggtggaa gccttcttag
     4441 gtatctttac cccgttgata acgatgtcat aaagcatgcc gtccatgagc tgatttacaa
     4501 aggttgcctt accagattga tccgttttac ctattgccct gatagctccg tatcgatttt
     4561 tcagcacaac ctcttgccct gctagtttat tgccattggc atcataaaca gttactattg
     4621 ctggtgtctt agagtaaaca acaggctttg ttcctttacc gtcgacataa aaagcagcag
     4681 ccttatgctc attaggctca ctcgtgcgaa cagtatagcc ctgtagctta ccatcaattg
     4741 agacactgat attacgtgat agtggtagct tggtaaagac tgcttgacca tcagcatttg
     4801 tctttgctga agcaattgtc gtcctagcac cgtctatcaa agcagtcagg ctgacctcct
     4861 tgcctgcgac gactctatcc tctttatcta gagcagtgac aacaaaatga aagccttcct
     4921 ctagcggact tgcctttcca tcctcctgct taggagtgtc cttggactga ggtgacgtac
     4981 ctgatgacga gcttgatgag gtgtcaaggt aagcgttaac agacattttt gtcatgacct
     5041 gccctatata cttgccattg agctcatagt gataaaaggt tccgtccagc aagcgatcct
     5101 tgaaggttac ctttccattt ttatctgaga caagacttcc taccagctga ccctggcgtg
     5161 tttttagggt gactgtttga ccttctagag gctcactgtc ttgattgcgg accgtaatat
     5221 caatgacatt tttactataa ataggctcct ttgtccctgc tcccttggcg acaaagctgg
     5281 ctgcctcttt agatccggca agactagttc tcactgtata gcccttggtt tccccgtcaa
     5341 cagaaacgct caggttacga ttcaagggca gttgagtaaa aatagcctgc ccgtcactgt
     5401 tagagacagc agaggccacc tgcttagcag gattagctgt cgtgtctgac aagacgactg
     5461 tttttccctc aaggacgtga ccgttgctag caagtatcgt tgcaacaaaa tcaaagccct
     5521 cagctgtttg tgacgtcgca gctacagcgt tgtctctggc ataggtcgta taggtgttga
     5581 cattggctgc taaggccaag ctagatataa cagtaaccgt taaaagactg acttttttca
     5641 atgactgttt cttcataaaa aagctccttt attttgatta actagcctag ttttaatggg
     5701 gaatatcccc ttgataccct ttctgaggtg ataggaacag cagcgacctc tcttagtcta
     5761 ctatatctag gcttcaagac gagagcctca aagtcttcaa gcaacgaatc tacaagaaaa
     5821 gcaaccacct ttaccacagc agagggcacc atgtgagcaa acgacaagag ccgctagcca
     5881 agttaaggca atgcctaata gccactttag ctgctctcaa ggctgtcgct gcagtgatga
     5941 tgtgattgtc tacacttttt aataaaactt aactagttaa gatttttgtg ctgctatcct
     6001 atcaaataac ccccgccaag tcaacaacaa tgctcatacc acagcaagca aagcattttg
     6061 atgatgactg aacagccaaa tcagctgggc ctccggcagc aaaaaagagg attcaaacca
     6121 aatcctctct ctactaagcc tgctactgtt gacatatcat gctaaaggca aatggtatag
     6181 ccacgctgat atgaaggtct gattaacagc tacgacagac acgcttgcta aggctaccat
     6241 tgccaatcac actaggtcat atcctccacc gtataagaat gactaacttc attattcaga
     6301 ttaacgatat acctgcaggt gctgaggaag taccttgaca gtgattggta aggcctcacc
     6361 ctcatcaccg tccacattga tagataattg tccttccctc atggcaatag tagcctcctt
     6421 gaaggtttga tagccaagcg tttgatctga agcctcaacg cccttcaata ggctaggaag
     6481 ggcctttacc gtttctaata gattgctatc ctttagatag ataaggtgca gcagaccatc
     6541 gtccacacgc gcctctggca aaatacgctc gaagcccccg attgaattgg tcaagccaat
     6601 caacagtgtt gtgctattga tttcttttgt atcgccatca atatctagct ggaaggtgta
     6661 gcttttattt ttaatcagct gcttaaagcc tgacataaaa taagccattt tcccaaaggt
     6721 cgtcttctcc tcaggggcaa catcattgat cgcctctggg agcgtcccta tggcaacaac
     6781 attcataaag taagcatcgt tgaccttacc aatatccaga ggactggttg tctcaaagct
     6841 tatctgatta atcgcttcct ctgggtctaa cgacatgccc aaggcacgtg ccaaatcatt
     6901 gactgttcct agaggaaaaa agccaaactt agggcgatag tcctgctctg caagtccgct
     6961 gatcccttca ttgacagttc catcacctcc catgacaaag acactgtcca gccgctgctg
     7021 ggctgcctca tgagcaaacc gtttggcatc tcctcctttt tcagtgtgct taacgtcaac
     7081 atcatcaaaa tacgaagcta gtttatcata ggctaaggct tcatattcct tggccttttc
     7141 accgccagag ctaggattaa caatcaatag ggcttttttc atttatgata tcctatattt
     7201 tctattagat ttcacgacta ttataatcat tattcaaaat atcgtcaaat aatactcact
     7261 atgtcattag tcagtcttaa agcttctaat atgattgccg tttaatgttt cattttactg
     7321 aactctttac ccagctagct caatgcctaa ccaatcgtgc tgtctcttaa ggtcaactct
     7381 gtcgccaata tcgtcatggt cttgacacgt tctgggttaa ggatattcct attaagcaca
     7441 tcaacagcca tacgtcccat atcctctgta aatacagtca cactagaaag cgcaggaaag
     7501 acctgtcttg ttaaaggagt atcgttaaag gagataagct caacacgctc aggcaccgca
     7561 agccctcttt cttggagagc tcttagagca cctattgcaa gggtatcatt agcaataaaa
     7621 aatgctttag gcaaatcatc acctagctcc tcaattgcct gtgtcataag ctcatagcca
     7681 gattgtgctg aaaaaggacc gatatagaca tacttcggct gataaatccc atgctcagag
     7741 gcataatttt tataggtgcg aaagcgctgg tccactaaag cttctctacc gtcagttgtc
     7801 ttttcctcac cagcaatcat gccaatgcta taaatccctt tagtcataaa ataatcaagt
     7861 acctttagca ctgcattgtc aaagtcagtt gtgacacagg ggtgccccaa ttcaagcgta
     7921 tcgctgtcca caaataccaa atgctgggat aaagcttcaa gctccttgat ttgataagca
     7981 ctaaactttc caatagcaat aatcccggca tggtcatctg aaaccctcaa aatgtcattg
     8041 ttgaaataac gaacaatatc ataatccaat tcataagctc ttttttcaat gccaatgcgg
     8101 atcgcataat agtagaggtc attgagctcc tcttcttgag aataccattg aacaatagct
     8161 atttttagct ttgatttagg gctattcgtc gcttttaaat gcttttggta gcccagctca
     8221 tcagcaattg tgagaatgcg gtgctttgtc tcttgaccaa tagacaagct ttggtcctta
     8281 tttaaaactc tagaaacagt tgcaggagaa accttggcca gagctgcaat atccttaagc
     8341 gttaccatat caaaccttct ttctaatctc tactagtata tcacaagcat ttttaaaagc
     8401 aatatttagt aaaattttag taaaaatatt gacgagtagt ttagcgaagc gtaaaatcaa
     8461 gctatcaaca tcgttaaagg agtcgctaat ggatattgcg caacttaagc aaagctttac
     8521 tgacgttttt ggcaaggagc cagatgctgt ctttttctca ccgggtcgca tcaacctcat
     8581 tggtgagcac actgattaca atggtgggca tgtctttcca gctgctatca gtctgggaac
     8641 ctatggactg gcccgcaagc gtgaggatca gcagctgcgc tttttctcag caaattttga
     8701 agaggctggg attattgagg ttgacttaaa tcagctggcc tttgataagg ctgacctttg
     8761 ggctaattac cctaagggag tcctctcctt tttgcaaaaa gctgggcacc ctattgatac
     8821 aggctttgag ctttacgttt ttggcaacat tccaaatggg tctggcctgt cctcctcggc
     8881 atcactggag cttttgacag gcattgtggc acaagagctg tttgagctca atgtggatcg
     8941 gttagatctg attaaaatcg gtcagcaagc tgaaaatcac tttatcgggg tgaattcagg
     9001 tatcatggac caatttgcta taggtatggg agctaataag caggctctat atcttgatac
     9061 caacacctta gcctatgagg ctgttccgct tgaccttggt gatcatgtga ttgtcatcat
     9121 gaataccaac aagcgtcgtg agctagctga ttcaaaatac aatgaacgcc gagcagagtg
     9181 tgaaaaagcc cttgaggaat taaatgccct tcttgatatt aaagcactgg gggaattaga
     9241 cgctcagcgc tttgatgagt acagctacct tatcaaagat ggtaaacgtc tcaaacgcgc
     9301 tcgccacgct gttttggaaa atcaacgaac actccaagca agacaggccc ttgaagcagg
     9361 agcattggag caatttggtc gtctgatgaa tgcttctcat gtatccttgg agcatgatta
     9421 tgaggtcaca ggccctgagc tggacacact ggtccacaca gcttgggagc aagaaggggt
     9481 cctaggggct cgcatgacag gagcaggctt tggaggctgt ggcattgcta tcgtggctaa
     9541 ggacagggtg gatagcttta tagaaacagt tgaaaagacc tatactgagg tcattggcta
     9601 tgctccagcc ttttatctgg ctgagattgc tcagggagca cgactacttt caaggaaata
     9661 agatatggca agcttaatag acacctttgt aaggaaggtg attgaacaca gcgactacac
     9721 atcagaggac gctatttata tccgcaatcg ggttttagca ttggttggtg agaaccatgt
     9781 ctggcaagaa acctccttaa cagccttaat agctctcaaa gaagcattgg ttgagctagc
     9841 tgctgaaaat ggcaaaatag gcaggcttcc tgaagaaaag gactgcttag gagctgaatt
     9901 aatgaacatg ataaccccta ttccaagtgt ggttaatcgt cgcttctggg atacctatgc
     9961 acaatctcct caacaggcta tctcagattt ttaccagctt agtcagctaa atgactacat
    10021 caaaacagca gcaattgcca aaaacatctc ctttacagtg ccttctcaat atggtgatat
    10081 ggctattacc attaacttat caaagcctga aaaggaccct aaggccattg cagccgctaa
    10141 gaaggctaaa gcatcctctt atccaaaatg ccagctttgt atggaaaacg aaggttatca
    10201 gggacggatt aaccacccgg ctcgagctaa tcatcgcatt atccgtatga gcttaggcaa
    10261 tgaggcttgg ggattccagt attcacccta cgcttatttt aatgagcaca gtattatttt
    10321 taatactgag catgtgccaa tgacaatcag tacaagcacc tttagacagc tccttgatat
    10381 tgttgatatc ctgccagact attttgtcgg ctctaatgct gatctgccta ttgttggcgg
    10441 ctctattttg acccacaacc attatcaggc cggtcggcac gtttttccga tggaaatcgc
    10501 aaaacaagac aaacgcttta cctttaaagg atttccagac atacaggctg ccactctcaa
    10561 ctggcctatg tcagttatcc gactgcgcag cagcaacaaa gatcagctag ttcaattagc
    10621 agacacgatt cgactggctt ggcgtcatta ttctgacgac agtgttgata tcgtcgctta
    10681 taccaaccaa gagcctcacc ataccatcac acctattgcc agaaaaaaag aagggcagtt
    10741 tgaattagac ttagtcctac gtgataacca tacctctgag caatttccag atggtgttta
    10801 ccacccacat gccgatgtgc aacacattaa gaaagaaaac atcggcctta ttgaggttat
    10861 ggggctagct attttaccac cgcgcctcaa agaggaattg gttgaggtca aaaaatatat
    10921 cctcaatcaa gccaatcaaa tcgcagacta ccacaaggac tgggctgatc agatcacatt
    10981 acgaccagat ctctcagcga taactgttga tgacattatc caagaagagg tcggctctgt
    11041 ctttgttcgt gtccttgagg acgctggcgt ctacaaacgt gatcaagaag gtcaagcagc
    11101 ctttatgcgt tttcttaaga gcattggcat tgaagcaatt gaagaatagg aggaaaaaat
    11161 gactgttcta gttttaggcg gtgcaggcta cattggatca cataccgtag accgtctcgt
    11221 agcacaggga aaagaaaaag tcgttgttgt tgatagcttg gtgacaggac accgcaaggc
    11281 tgttcaccca gaggctatgt tttacaaagg agacttagca gacaaagcct ttatgcgtca
    11341 agtctttagg gacaatccag acatagacac tgtcattcac tttgctgcct cttccttggt
    11401 cgcagaatcg atgacagacc ctctgaaata ctttgacaat aacacagcag gtatgattaa
    11461 gctgcttgag gtcatgagag aagccaaggt taagcgcatt gtcttttcat caacagcagc
    11521 cgtctatggc attccaaaaa cagttcccat cttagagtca gcgcctaaat gcccaatcaa
    11581 tccttatggc caaagcaagc ttatgatgga aacgataatg acctgggccg acaaagccta
    11641 tggcatcaca tttgtggccc ttcgctactt caatgttgct ggagcaaagc cagatggctc
    11701 catcggtgaa gaccatgagc tagaaacaca tttattaccc attatcctac agactgcaca
    11761 gggagtgcgt gagcaggtga tgatttttgg tgatgattat gacacaccag atggtactaa
    11821 cgttcgagat tacgtccatc ctatcgattt agctgatgca cacattttag cgatggcata
    11881 cctgcgtcag ggcaaaccat cacaggtctt taatctaggg tctcaaacag gcttttccaa
    11941 tcgtcaactg cttgaagccg ctcgtcgggt aacaggacaa gccataccag ccaaaaaagc
    12001 tgcgagacgt cccggtgatc cagacacctt aattgcgtca tcagaaaaag cacgcaaggt
    12061 tctcaattgg aagccaagct atgacgatat tgacaagata atcacatcag cctgggcctg
    12121 gcataccaag catccaaaag gatatgacga taaagcaagt ggcagctagt ccctcaagac
    12181 agctaccaca gtaagtactc agcctccctt aattcataca cctatactaa taggagaaac
    12241 aaactgtgaa catttatcaa gacatcattg aatacatcga tcaagtacca gtcacccagc
    12301 taagactgat taatgctaac ggtgttgagg ctcacctgct gacactagga gcgaccctac
    12361 aggcctttct agtgccaaat gaaaagcagc caaaaaatat cattttggga cataaccgac
    12421 caagtgacta tctaaaaaac cctctttgtg cagggcaaac cattggccga gtagcaggtc
    12481 gcataaaggg aggaagcttt cagctagagc agcaaagggt ttgtgttgac accaatgaaa
    12541 atgggcattg cctgcatgga ggcttcaagg gctttcataa gcttcattgg ccttatgata
    12601 cccgccaaac agctgattac cttgaagtaa cctttaaaag ggatatttta gaagcagatg
    12661 accgtttccc aggtgacctg accgtaagca ttacctaccg tctagacaac cataatcgtt
    12721 taagcattca ctttaaggct catagcatga gaggcactag cctattcaat ccaaccaacc
    12781 atgtttattt taatttaggg caaacacaag acctaaccaa tcacagccta cacatcgcag
    12841 cctcacatag gattgaaaca gataatgagc taatcccaac aggtcaaaag ctagcagttg
    12901 accagacggt ctatgatttt agatcaataa agcccctcta tcctgctatt gtcgaaaata
    12961 atggctttga taccgccttt gaaattgatc agcaggctat tggaacaacc caacccattg
    13021 ctgtcttaca agacagcatc agccatgacc aaatcagtat ctactccgat cgaaatgcac
    13081 tcgtcattta cactatggac agtatccaag atggcttgta ttttggaaga gaccagggca
    13141 aagtgggact tgctcgtgag gggatcgcta tggaagcgca aaccctgcct gatgctatcc
    13201 accacaacca atttggtgac attatcctca aagaaggaga catcaaaagc tacactatct
    13261 gcctagccta tgaacatcta ccagactaga taaacagcag tcaagctcta ataaagtaac
    13321 aagaccttga tttttttgaa ttgcacccca acagttagcc aaaaactcta acaagctggg
    13381 gtcagttcat gcatcaaggt ctttttgtct atagtcgtta caaaacaagc ataggaacaa
    13441 gcataccaga tgtgttcaaa agctaacacc ttatcatcac aaagcgaata cctgttcaaa
    13501 ccatatctat gtgtcagtga gtctttcgct taaacaaagt gttgccagcg ttataggata
    13561 cttaaaagat aagaacagtc taatcatttt taacaaagac gccaacctca agcagaaaca
    13621 tagaaatcag aagttttggt gtcttggtta ttatggagac acagctggta aaaacctaaa
    13681 aaagatagcc aattatattc caaatcacta tagaaagata gggtagcaaa ccaactgaca
    13741 tcatttgata ccattgatcc attgacaggc cagccaaata agaaaaaata accttggcgc
    13801 ttgagctgcc gctcagaaaa gtgggacgcg agtattcaat ggcctcgtta tcctcgatcg
    13861 atgagagcgg cttatagcca tagtactaaa gaggctggaa cagacaacct cttttgattg
    13921 acaataaatg tttgatagca ttttatggga ttactttcac atcattcagc acctgggtcg
    13981 agctttgatg accgccagaa ttgctagcca ttatgaaggg ctttgagcag ccatttctgc
    14041 tttatcgaac cataaaatat cattgatgac tgctccaaaa ggacagtcat aaactgtctg
    14101 atcagcgctt ctagtcacga acctttaagc aaaccttaat actcaaaaaa ggtaagtcag
    14161 aaaatacttg atttctcaga tgagctgtgg aattaccacg acctttacca gctcttgctc
    14221 tttcattttc aaaaagtggg taacggagtt tttcgggctg attgaagagc tttgagcttg
    14281 gtcaatcatc acgttttaac cgtcctcaaa atctttttga aatacaaacc ctacatcaca
    14341 aatgccttat tccaatgcta aattggagcc cactaacaag atgattaagg acatgaaaca
    14401 gcaagccttt ggatttagga actttaagaa cttcaaagtc aagattccca atgctttaaa
    14461 catcacaaaa gaagagacaa aatttatctc ttctcgtgct tagctatcag tcacccactg
    14521 cagttgacat tgagccaaat tatagagcca ttttcgtaga aagcacagaa aaacacccat
    14581 gaggtaaagt cttgagtgct ttgaaacgtt gatataatgc gatatattaa cgttttgagg
    14641 cacggagact gcgtctcctt tgcagccgta ttcgtaagcg actaaagccg caacgactac
    14701 gtcaattgcg tcgccagttc tttcaaaaaa gaaaataccc catggtaacc catgaagtat
    14761 tgttctgctg tattgtagct ggttcttaac gtttagagaa ctggctagct ttacgagctt
    14821 tcttaagacc tggtttgaaa gaatcttgtt tgaataaat
//
LOCUS       DARYSY010000051        14151 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYSY010000051 DARYSY010000000
VERSION     DARYSY010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14151
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(230..1909)
                     /locus_tag="TVR04_001545"
     CDS             complement(230..1909)
                     /locus_tag="TVR04_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270222.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIHLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLKQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQDPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2084..6988)
                     /locus_tag="TVR04_001546"
     CDS             complement(2084..6988)
                     /locus_tag="TVR04_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1270223.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGIGSVAAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLGD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADM
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRVDLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKDLTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAVGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGDGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIEAAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASSFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLRDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAAGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQASVYKATDTDRKELLWISPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQKPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDSLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDIDAQHQLSYSDDLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMAGHYRYVVSYLDA
                     NGMPQAETYGVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSKVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSFGAAGSCQRQKKY"
     gene            7341..8168
                     /locus_tag="TVR04_001547"
     CDS             7341..8168
                     /locus_tag="TVR04_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1270224.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDSLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8243..8596)
                     /locus_tag="TVR04_001548"
     CDS             complement(8243..8596)
                     /locus_tag="TVR04_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1270225.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSIEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8600..9112)
                     /locus_tag="TVR04_001549"
     CDS             complement(8600..9112)
                     /locus_tag="TVR04_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1270226.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVSLIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLRRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9568..10122)
                     /locus_tag="TVR04_001550"
     CDS             complement(9568..10122)
                     /locus_tag="TVR04_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1270227.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKAALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10333..10962
                     /locus_tag="TVR04_001551"
     CDS             10333..10962
                     /locus_tag="TVR04_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1270228.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVSRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGNFVYNDLELRAMEADILKAIEAGTDALVMGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11436..12521
                     /locus_tag="TVR04_001552"
     CDS             11436..12521
                     /locus_tag="TVR04_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270229.1"
                     /translation="MMTRYFYKLLLTILILALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETVSRTQHKLFERESFKQANQGYFAKTREGNDLKILLTHIDQASL
                     EGKILHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDCHLKKQAHKSIPNRDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERIIRFEELAGQETNSPYFMMTSSNYYFLFPKRLYRYDC
                     SSHQMTCINLDQYGVTHAHAMIAKPTL"
     gene            12935..>14151
                     /locus_tag="TVR04_001553"
     CDS             12935..>14151
                     /locus_tag="TVR04_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1270230.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFIGGSARVLAEQYYGYDDGTKNG
                     GEWPAFLYVTPTDHPERKTDTDHCVYCFNRDNAYPNPWEANTYQRPDILQFPLPIYNR
                     HLGDDNLLGMYSKTHAKNLAVTLGVLLENGYPRKLLGNLDADKSRRLTQLAIWHFTDG
                     YQAQLFQQNYNLSPEENKELMNLISLAKAGKLSANYNLDLYITADPLIKTGQKPFQQL
                     LGSTARNKVPENNNSCQCTKIYITEGSGGYWIYTYIDENNNNVKDSNEKELQKVFVKN
                     GKDGKPGLNGQRGPKGEEGKPGPAGPQGPQGDPGKDGKPGEKGPKGDRGEQGIPGPKG
                     EDGKPGPKGDTGDRGPTGPQGPRGENGKDGKPGHDGQPGPKGEKGDPGKQGPQGERGE
                     QGPQGERGEQGPQG"
BASE COUNT         4092 a         3416 c         2858 g         3785 t
ORIGIN      
        1 ttttaaaagg caaacaaaaa ccatgccaca ttgcaatgac atggttttct tcaagaaagg
       61 agcgagcttt ggtttggtgc ttttttacaa ctgatctcca atagcagctg ctcctcgtta
      121 gtccctgagc cacaggtgac tgagctttcc tgcggctact ctgatagtac cagctactct
      181 tacaactgca taaagcagtg gctgccagcc aagctaaagc taaacaatat tactctgtta
      241 tagcttggtc tgctgacgag ctctcaatgg tcatgtgatt gaggtagttg tcatcagcca
      301 gctgagcctt aaactggtct ccgaccttta ggaaaggcag acggtcacta gtttcactgc
      361 ttgccttgat tttataaatc tgacccttgg aggaaatgta ataaaccgtt gttcctgaga
      421 taatctggct ggccaattgc tccacctgcc cagtaatcat cttgaccttc tgatcattgg
      481 tgtctgacac tgacagcgag cttgtgtcct tatctgtgaa ttgtgagatt aaggtctgaa
      541 tgtcattatt cactgttacc tgctgataat cctctgcatc aaccaaggca taggatttta
      601 tcagaccagc cccgtccttc aatgagataa ggtaataagc cttgtcattt aacttgacta
      661 gggttggtgc agttgcagtg tatttcttct cttgaacttc gccctcggct gatttcatgg
      721 cagaggcctc tgttgcagaa ggcagcttat agttagtgac ctctctggta cgcatgttaa
      781 ccaaaataaa gccgagattt gacgaatcag ctgttgctga ggtgattcct gtatagaggt
      841 aaatgtctga gccgatggta atgtagttat agctgtctgt tgtttgcttg acatctgtct
      901 ggctaaagac agtgttccaa tagccctttt gataggtgta atagtcatta accctctcca
      961 aaacattgtc agcagaatag acacgatcaa cccattttgg aacgtccttt agctcatagt
     1021 attgagactt gccgctaacc gcgtctaaca ggattacacc tgtcggatcc tgagaggaca
     1081 ggccaaattt tggggcgtag gttgttgcaa catagtaagg attaccatca tcgtcaacct
     1141 caaatgacgg gtctgaaaaa atggtcatcg ggtattggaa gcgcaaatgc ctcattgtat
     1201 ctctaaacat aaattccgaa tgagaatact tcataggctg ctttaacttg actagctctg
     1261 ccttaccagt tgtctgattg accttgacat aatagccaat accgtcctta cgattggtta
     1321 gccatttcca gaaggatttg tactccaagg gagaaacacg ataagggagc ttgccgatcg
     1381 taatctgacg gtactcatca gaaataccaa actgcgatac cttatcaatg gtcccaagat
     1441 aagtatctcc aatcttttca gccgaatctc gatccagcaa tgccaaggct gacagatcag
     1501 tgtctggaaa atccttgtta aaatcagcgt cctttacctt aatcacatga gcataggact
     1561 tagcacgaaa cattctagtg ttaacagcta gcagcaagga caagccagca atgataacgg
     1621 caagggcaag accaagccac tttatgccac cggttaattg cttgagtgaa agacctgagg
     1681 tcacgtcctt gcggccagac ttttgcgtga aaaagctggt cactgttttt ttcaacccaa
     1741 acaaggacag gataaaaaga ctcaccatcg ccaagataag cgcaagaatc acgaaaaacc
     1801 aaaattctaa gctcatcacg ttcattggcg gcaaatgaat ccagtaaaag ccagccagga
     1861 tcaagctgtc taagccaatc agcaccaaag aagcaacttt ttttgtcata ctaatctcct
     1921 cgtcacaccc taaggctatc aggggtattc aatatcttct caccgctatt gtaccacatt
     1981 tcccctcaaa atatgacatc tcagccagac atttttatca gctcttagag cacctcagct
     2041 agagtgatca atacagctga caggctacgc tcatagagct tgcttagtac ttcttttgac
     2101 gctggcaaga gcctgctgct ccaaaactga gcaagcctag caggactaga ttgaccgctg
     2161 cttgctcacc cgttgatggt aggacttggg cttttttaac tgcttgtgct gttagggcag
     2221 agctagtgat tgatgagccg gtataatgag tcaagcctcc agcctgatgt tctagctgag
     2281 gctgcttagc tttgataacc tcaaaggtaa gctcaatcac accattatgt gatacctcta
     2341 gacctccttg accgattagc tgatagccct ccggtagctc aacgaggacc tcatagcttc
     2401 cttgtcgcag tgttttacca taggcacttg gaacatagag agacggagct agagaaatca
     2461 actgaccatt tgctgctttc aggctgacct tgctgccttc tggcaagact tggttaaaca
     2521 agagccaaac agaagccaca ataggccttg tcatctcaaa ggcaactgaa gcaagccttg
     2581 tatctgcatc tagactaaag ctaaccaagt tgtcagacct tagctcaaac agatgattat
     2641 cataagccaa gagctcaacg gtgtagcgtc caaatggcaa tatcaagcta ttagctgagc
     2701 tattgaaata atccagctgc tcgattggct tgccctgctc atcacgaata agataagtaa
     2761 aggctggctc ttttttgttc tcaagcacat caagtgccaa ggcaacggac actactccct
     2821 tgtctggtcc tacagctcgc aaagcagcta agctcatata agcaatctga cctgcctcgt
     2881 cttccactag ataataataa tctgcttctg caacgccttc aaccttagga atggtgtagg
     2941 tgccgtctgc attttgagca atcatcacct tattatcctt gaatctgatc agctgatctt
     3001 cgacagttag atcaaacttg cgtccatctt tcttgacaag gtagaagacc tcttctctaa
     3061 caatacctat tggactttgt cccttgcttg gtcccggacg aaagacctca gtagcaccat
     3121 cagcttggaa gctggctggc gtaatgactg gcttttgatg gctgactgtc accccatagg
     3181 tctctgcttg aggcatacca ttagcgtcta gataagaaac aacatagcga taatgtcctg
     3241 ccatcaccct agctcctgag gctcttgtgc cataccaagc ggtgctgtca acattagcca
     3301 cgcttgcacc tggttggcta gaccagattg ggcttgtcat agctgtatcc tcctgggcaa
     3361 agaccgttac ctttagatct tgatacactt gatgtggcaa gcccttgaat gccacaaaat
     3421 ccttgtttcc atcatcattc ggcgagatga cagcggtttg acctaattta gccaaacgac
     3481 tctgtggtct attgcggcta ataatgagaa gctctgcttc atttgtcacc agtcctgtat
     3541 ctgcagcagt catgttgagg tcatcactgt agctcagctg atgctgagca tcaatatcag
     3601 ttagggtcaa tgccaactca gcctgaccga ttttttctgg caagtgattt cccagcttag
     3661 caatggcaac attgcctgca aaatcctcga ccatgtaata aaaatcacca agcgccacct
     3721 gatccactgg caggacaaaa gagccatctg ctaagcgctc aacaaactgc ttattatctg
     3781 atacggtcac atactttaag ctatcattaa tggtaatcgt ataaggcttg tcatcctttg
     3841 tttccaagta aaaaacacta tctcgaagaa caccagcctg accgcgatca agccactggg
     3901 acggtctgaa gcgatgggtc acagggttat agcttgccgt tcctagctcc ggcttttgac
     3961 gatccacaat cacctcaaag accatttctt gacgtttcgc tcctaccaca tctggataat
     4021 aagaaaccac ataatggtat ttgccatctg gtaggtcagc tccggtcagc gatttaccac
     4081 taaagcctgt ttctaacagc gttgttgact tggcaaagcg aatatcactg ttaaagtttt
     4141 tatccccttg aagggctgat gggcttatcc agagcaactc cttacggtct gtatctgttg
     4201 ccttatagac actggcttgc aggccttggt atttacgtaa gaacacccct ttgaaggcag
     4261 caaagtcttg attgttgtcg ccatttggag agatagccaa cacaggatag ccagctgcat
     4321 ttcgctccaa cacaaattta ccgtctttat tacgaaaggt tcctagtgtg tgcaagccat
     4381 tgtcagcaat agtagtcata gagacattgg tatctgtacc aacagtcacc agcccggtaa
     4441 aatgattgcc aacataaatc tcgtccctta gccctgagct gtcaaaataa aagccagttt
     4501 ttccttgagc ctttagctca taaatagagg cttcaacaac aggtaagttt tcaaaggctc
     4561 ccttaaagcc aacaaatgga atgttgatgt tatccttatg ctcgtccttg ctatccacaa
     4621 agcgaacaaa gccctcaagg taatagccat ttggcatttg cttagagagt tcctctgtaa
     4681 agcttgaggc atctagggta atggtaatgg tcttgtgtcc ttgagcaggt acgtcaacct
     4741 gttctccctg ataggttttc agagatcttg aacgtaaggc aaaacgtcct tccttagtat
     4801 ccacctgatc agtcaacaat tctgtctggt agcgcagcga cttagcctga ttagacaagt
     4861 tatggattgt cacctcaaag cttatctgat cagtcacatt tccaagagaa atactgccat
     4921 agttgtcttt acctgtcagg tacagaccac tggttaccgc ggcctctata ttcaagagcc
     4981 ctgctccctg ctggcgtggc gatgtggtgg tattggtctt agggttgatg tggatctgag
     5041 cattactcat cagtatattt ttaaccagat ctgctagctt atccttggca agctgtggtt
     5101 gaagcgcttc tagatattgc ttgaccaaaa ggcttgcccc tgcaatgtgt ggggttgcca
     5161 tactagttcc tgactggctg ccatagtgat catcgttgaa ggtcgagtaa atatctccac
     5221 ctggagcagt gatgtcaggc ttcaaatagc catctgaggt caagccccag ttagagaaat
     5281 agttcatctc atttcccttt tggctaatgg ccttagagac ctcagcatca aaggtcagag
     5341 tgcctgtccc atcgccattt aaagcagcca ttgccatgcc aaattcatga gagataaagg
     5401 cagatggcag caccatcccc tttgaactca gacgcatggt gcggttagcc ttgcctggct
     5461 cattgttaaa gatcaagacc ccgactgcac catactgctt ggcctctgct ataatatcgt
     5521 cgtatttccg attaggatct cgctgtacca agacaatctt gccactcacc tcacgttctt
     5581 ggtagccctc ttttgtcaag tctttgacat aaacaaagga gtatggtaca tcaaagccaa
     5641 gactagtctt aatgtccttg aaatcaacag attccaaata gatagccttt ccatgattta
     5701 agtcaaccct atccttcaag ccctcaactg tcatcagacg ctctataatc actttgttat
     5761 taatagacgc aactgaggta ggagtccgac ctgctgatgg agcccccact aagccataat
     5821 caggatttgt caccaacggg tctgcatgat ctgacccaaa ggcacgctca ttacctgcag
     5881 caacgaccac agagacacca gcctgccttg ccttttcgat agctgccatc agggcacgat
     5941 tcccattcaa ttgagaccca ttggccgagc ccagacttaa attaatcata tcagcaccca
     6001 gtgccacagc atcttcaatg gctttgataa acaagggatc tccagttccc atcaaatcat
     6061 gggtaaaaac ccgcataaac atgacctgag cctccggagc aatgcctaaa aagcgttctc
     6121 ctgctgcggc agcctttagg ccatttccag ctgcaatgcc tgtcacatgc atgccatgcg
     6181 attcatattt gctgtcatca tctgtatctt gccagtcaat gatagttcct cctgatgtgt
     6241 catcaagctt gataaccgtt tcctgaggtg cctctattga ctgcggacgg ttcctcctaa
     6301 tatcaatctg ctgcacaatc acatcaaaat ccaaatcgcc aaggccctca aacggatcgt
     6361 cctttatctc ctttacctta tcattgtttt ccacatagtt gtgggcaaag actaccttat
     6421 cgcttagcca gacaccgtac tgaatgcctg ctgctttttt gcgctggtca atatctgcct
     6481 ttgatgtaaa cttagcagct gctgggtttg taatgcgcat ggcatggtga ctagcgtcaa
     6541 taccagtatc aataacagca ataaccttac cttgaccctt atagcctcta ttccaagctc
     6601 cttctgtttt tatccagcgg tgagtatcca tatttactgg aggtagctcg cgcgattctt
     6661 cttgctgctt gactgattgg ttagattccg ttagcgcttc catttcggaa gaaactaatc
     6721 cagtcgccat tgcctcctct gtcttttcct ctgctttact tgactggctg tcgatgtcct
     6781 gagcattaac agcagctccc tcactagcct gagagacaga tagcacctcc cttgattctt
     6841 gatgttgtcc tgctgacacg tgagctgagc taactccctg ctcctcagcc gcaactgatc
     6901 ctattcctgt cagaaaaagg attccaatca acacagaaac cattcctgat ttatatttcc
     6961 tcagtgagaa gcgttctttt ttctccactt gatgtcctcc tagatttatt aaaaaaggtt
     7021 attttaaaca aatgattcat ttatgtttta atcaataatg tctaagctat ttaaccattt
     7081 tttaatcaca aaagcaataa gactagaagc tctcagttta tgtcattttt taatcattca
     7141 actcactgaa atgaggcctc tcagaacctg tctcatcaac agataaggct aaactcagcc
     7201 gctagacttc aaaaatgtca caccattttt agacattacc tgtcctcata cctataacag
     7261 aaccaagctt ccacagtcgc cttggcctta tttttttgtt acaatatagg ttaagattat
     7321 catttagaaa gcgaagaaaa atgaaactca tctcatggaa cattgactct ttaaatgctg
     7381 cgctcactgg tgaatctcct agagccctct tatcacgcgc tgtgcttgat agtctcgtgg
     7441 cacaggacgc tgatattatt gcaattcaag agacaaaact atctgccaaa ggccctacca
     7501 aaaagcacct tgagagcttg cttggctact ttcctaatca tctcaatgtt tggcgttcat
     7561 ctgttgagcc tgccagaaaa ggctatgccg gaaccatgtt cctctataaa aaagagctca
     7621 atcccattgt cacattccca gatatcggag ctcctaccac tatggacgct gaagggcgta
     7681 tcatcaccct agaatttaac gatttctttg tcacacaggt ctacacccca aatgccggtg
     7741 atgggcttag acgcttggaa gagcgccagc tctgggacca aaaatatgcc gactacctag
     7801 cccagctcga tgcccaaaag cctgttttgg ctactggtga ttacaacgtt gcccacaagg
     7861 aaatcgacct ggctaatcca gctagcaacc accgctctcc gggctttaca gatgaggagc
     7921 ggcttggctt tacgaacctg cttaaccgag ggtttacaga tacctttcgc tttattcatg
     7981 gcgatattcc aaacgtttat agctggtggg cacagcgcag caagaccagt aaattgaaca
     8041 ataccggttg gagaattgat tactggctca cgtcaaatcg gttgattgat aaggttagtc
     8101 gctcagagat gatttcctca ggagaacgtc aggatcacac accgatttta ttagaaattg
     8161 atctatagac tagaggcatt cggacaaatc aacccagaca tcacaaaaac ggctctccaa
     8221 gagaaccgtt ttttttaatc gcttaaagac ctagatcctt ataggctgtt cgatacccca
     8281 cctgcaagac ctgattatcc tgtaagagga tcggccgctt aatcagcatg ccatctgttg
     8341 ccaaaagctc tgctgcctcc tcgatgctca gtgaattaac cttatcttta agcccaagct
     8401 cacgataacg cataccactg gtattgaaaa agcttttgag gctataatct gagtgttcta
     8461 gccattgttt cagctgctca gctttagggg gattggcctt aatatcaatg atatcaacct
     8521 cagaaaccaa ggtctttagc tcagcaaggg ctttttgaca ggtactacac tttgggtatt
     8581 ggtaaatggt aatcatcagc tactccttat taacactaat ttgctcgtgc ctgagcaacc
     8641 aggccttctt ttcaagtcct ccagcatagc caatcaagcg accatcagca gccagtacac
     8701 gatgacaggg aataaaaata cttaagggat tgcgtcctat ggcaccacca acagcctgag
     8761 ccgaacgaca ctgcaggcgc ttggcaagct caccatagct caaggtctct ccccacctta
     8821 tcgtctgcaa ttctcgccag acagctcgct gaaaatcagt accctgtggg gataagcaat
     8881 caagcatggg atagggcttc ctctcaaagt aagcatcaag ccacaaacag gctcttctta
     8941 acagggcatg ctgctcctgc cagatgggct gcaccttaat cccagcttga aaataccttt
     9001 gaccttcaaa ccaggctcct atcaaagaaa cgtcagtcgc aaccaaggat atttttccta
     9061 agggtgattg atacacacac tcgtacaatg gcaagatctg acctccccac ataatagctt
     9121 attcccttga ctatttatta taagaaaaag cctagctaaa ggcaagaagg agccctctga
     9181 cacctcaaca aacgcatgaa gaaaatacca actgcttcaa tgctgccata caatcgttag
     9241 tgtcaaaagc cgcttactat acagttgtcc cccttgaaaa acgaagctga aaagacacaa
     9301 catgctaaag ctgtttcaag cgccggtgtc tgattagatg ttgttctaat taaaggccaa
     9361 tgttctgatt aaaaagtcat ttcatgcgct gatacctact cagataggac cacataatgt
     9421 aagactaaac caatcactca caggtcatca gatagctcgt ctataagctg cattttatca
     9481 cattgggatc agcagacata tttgccggct cagtcgtgct tgcctgatag ctaactaaag
     9541 gcctcatgag ctttttctgg tcctatatca atagctgtag cggctatcct cgctaatctc
     9601 ctgataagcg gctctttcat ggcttttctt tattttttga taggctaagc gctcgccatc
     9661 aatcggtacc ttgccacaat aaacaaagcc tagcttttca atgatatgcc gcatgacctg
     9721 attatgctca tgagtatcta tccgaaaatc tggcccatgc tgcccctcaa tgagcccttg
     9781 caaaaaggtc tgagcaatcc cctgaccagt cctatcactc agcaccgcca cacgatgaaa
     9841 ggtcacatag cggtggtgat tatgctgcca cctgccatca taaatcttgt cgtaggcgtc
     9901 ctcttgacca tcaataacag ccgcataagc aacaatctgc ccctcaagca aagccacata
     9961 gccctgcccc tgcaaaacat cagcagcaat atcctgataa gcaggatacc catctgcttt
    10021 ctgccattgg ctggagcctg attgggctaa ggctgcctta gccgaattga tcaccgtcat
    10081 gatctgacta agctcattgg gaaaagcaag tctaatctcc atcgttcaca ctcacaatct
    10141 attctgattt gatgatgcta tactaccacc aaaagcctca caccttgtca cactattagg
    10201 gacacctcat agctttatga ttacctctca tctcagctga gtatagcaca atagtcatca
    10261 tttgacaaaa agcctcttca aggattgcca gcaatcgtgc tataataaag taaaccacaa
    10321 aggagaacca ttatgattaa agaattttgt gctgaaaacc taaccatgct aaaccaattg
    10381 accagccagt cggtcagtcg tgttgagctc tgcgacaatc ttgcagtcgg tggcaccaca
    10441 ccctcttatg gtgtcatcaa ggaagcctgc gacctcctac atgacaagca gattagtgtc
    10501 gcaacaatga tccgcccaag agggggtaat tttgtctata acgaccttga attgcgtgct
    10561 atggaagcag atatcttaaa ggctatcgaa gcaggaactg acgccttggt catgggctta
    10621 ctcactaagg acaaccagct tgacaccgat gctatcgaac agctcctacc agctacgcaa
    10681 ggactccctc tggtctttca catggccttt gacctgattg ctcgcgacca acaaatcgca
    10741 agcctagaac agctcattga ctatggtttt gtacgaatcc tgcttcatgg ctcaagcgat
    10801 accagatcca tctatgaaaa cattgaccat atcaagcagc tagtcaaggc tgctcagcac
    10861 cgaatcgaaa tcatgattgg tggaggtgtc acagctgata attgccaaga gctaagtcaa
    10921 ctaacaggaa cagctattgt gcatggcaca aaaatcattt aactatcagc tcaaataaag
    10981 gaaaagtcac tccctacaag ggggcaaata atagcgtctg ttctcgttga aagccatacc
    11041 tgagcccttg gactaggctc ctagtaaact aatagcatag gaacttcact gcctttacat
    11101 caaaaaggct gctgtccaga aaaaagagaa agccacatat tgataaaagc catagccagc
    11161 taccatagtt ggctctacta ctgtcagtat ctatcatcag cttctgagct gcctaaaagc
    11221 ttcggcgatt gttaacaact acagactatt tgtttctaaa ttaaatcata aaataagcaa
    11281 ttataggaaa tcattagtga atcattattc atttcctgtt gattattgtg atatcataaa
    11341 caaagagagc gctttctttt ttgtttttaa gctacttaat catttagact ttaggtttat
    11401 gtttaccatc ctacctataa gaatcggaat aaataatgat gacaaggtat ttttataagc
    11461 tattgctgac gatattgata ctagcattag gaggattttc cctatctgct tgccattcca
    11521 agattagtaa gccctatcaa gtcgctattt ttgacaagga tcatgttagg acctttatgg
    11581 aaaaagctga cagtctggtg cctgttgaga ctgtctctcg aacacaacac aagctatttg
    11641 agcgagaaag ctttaagcag gcaaatcagg gatattttgc aaagacaaga gagggaaatg
    11701 accttaagat cctgttaact cacattgatc aagcaagcct agaaggaaaa atccttcatg
    11761 ctgatggcaa tgacgcctac acctctacaa ctgatggtga ttacttttac acaacagctg
    11821 tctttgccga tcgtattgac tgctacaagt atgactgcca cctgaaaaaa caggctcaca
    11881 agtctatccc aaaccgagac accattaatg ccagcaatca gtttctggtg attgatgacg
    11941 ctctgtacct gcttgtcagt gctgtagaca tcaagagtca gcaacccaaa actgagctat
    12001 ggaaaatgga caaatccttt actatcactg atcggataga tctggacgaa agcactgcct
    12061 acctacgcat ggtcaacgtc ggacgaaccc tttacattac ccaggctgct gatggcattt
    12121 tagaaactgg agaacctaga cctggtaaca aggtgatgac ctatgactta gatagcggtc
    12181 aaaagtccta cctcatgctt catgtcaaca gtcctagagc catttaccac catgccaaaa
    12241 ccaatgagct tatcatcgaa aatgatcagc attataatcc tgactttgca tggaccatct
    12301 accagctaga taccggagag gaaagaatca ttcgctttga ggagctagcc ggtcaggaga
    12361 caaactcccc ctactttatg atgacctcaa gcaactacta cttcctcttt ccaaaaaggc
    12421 tttaccgata cgattgtagt agccatcaga tgacctgcat caacctagat cagtacggag
    12481 tgacgcacgc ccatgccatg atcgctaagc ccacactata aatcacaaca ggcctaatca
    12541 ccactcattc atctacaccc caatgcttag acaaagcagc taatcatggg gtgttttctt
    12601 atggactctc aacgctagca aagcctattc gtatgcgtta atgaatagac cattaatcat
    12661 taaccaaccg ccaagctttt gcatatagct catgagttat aaaaaccatt agcctgataa
    12721 gccccaataa caatgctttt ctagccttat ataagccttg ttgatgtgta acaatatcag
    12781 acaattaagg tgttgattaa aaaaaaaaaa aaaacgaaac tacggagacc aattatcaga
    12841 aagctattca cagccagcaa agggcatgct aaagtattct ctggaaaaag aaaggcttag
    12901 gaatgattat ttctaaacta aaaggagaga gacaatgaaa aaaacaatga agaagatgct
    12961 ggcagcctcg acgctctgta tcatcatgtc aggcagcttt attggcggct cagctagagt
    13021 gttggcggag cagtattatg gttatgatga tggtacaaaa aacggaggag aatggcctgc
    13081 atttctatat gtaacaccaa cagatcaccc cgaaagaaaa actgacacag accactgtgt
    13141 atactgcttt aatagggaca atgcttatcc aaatccttgg gaggctaata catatcagag
    13201 acctgatata ctacaatttc cactacctat ctataacaga cacctaggtg atgataacct
    13261 tttaggtatg tattctaaaa cacatgcgaa gaacttagca gtaacattag gagttctcct
    13321 tgaaaatggt tatcctcgta aactgttggg aaacttagat gctgacaaaa gtcgccgact
    13381 aacacagcta gcgatttggc attttaccga tggatatcag gcacagttat ttcaacaaaa
    13441 ttataatttg agtcctgagg aaaataagga gttaatgaat ttaataagtc ttgccaaagc
    13501 aggaaaactt tcagctaatt ataatttgga tctttacata actgcagatc cattaataaa
    13561 aactgggcaa aaaccctttc aacaactact cggatctact gcgaggaata aagtaccaga
    13621 aaataataac agttgtcagt gtactaaaat ctatataaca gaaggttctg gaggatattg
    13681 gatttatacc tatatcgatg aaaacaacaa taatgtgaaa gattctaacg aaaaagaact
    13741 tcaaaaagta tttgtcaaaa atgggaaaga cggcaagccg gggctaaatg gtcaacgcgg
    13801 acctaaaggc gaagaaggga aacctggccc tgcaggccct caaggaccac aaggggaccc
    13861 tggtaaagac gggaaaccag gcgaaaaagg gcctaaaggg gacagagggg aacaaggtat
    13921 tccagggcct aagggtgaag atggaaagcc tggtcctaaa ggtgatacag gagatcgtgg
    13981 tcccactggc cctcaagggc ctagaggaga aaacggtaaa gatggtaaac ctggacatga
    14041 cgggcaacct ggacctaagg gtgaaaaagg agaccctgga aaacaaggac ctcaaggcga
    14101 acgtggggag caaggacctc aaggtgaacg cggggaacaa ggacctcaag g
//
LOCUS       DARYSY010000052        13664 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYSY010000052 DARYSY010000000
VERSION     DARYSY010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13664
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            279..3425
                     /locus_tag="TVR04_001554"
     CDS             279..3425
                     /locus_tag="TVR04_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270231.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDASDGTAATVNAGDT
                     AAPSAEAKPSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATASTEPEKEQILSLLDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNDKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDEKNRTLHFLGLGNAEYATLKVDYNAS
                     TLTLKTKKTKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQVLTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKKDNKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYKASHQGIQLKMAIAVALEFTKPVGAWYNESQKIDPLERF
                     VTFAEAEQGNVLFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVGTNPETGVSVHSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
     gene            complement(3715..4803)
                     /locus_tag="TVR04_001555"
     CDS             complement(3715..4803)
                     /locus_tag="TVR04_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
                     /protein_id="HEL1270232.1"
                     /translation="MTISNDFEAIAKRHKRRLTLKYVVLSAGLALVALVLGYMGLNRL
                     TSINGQYLMAYYNNRIQIAYPNIDVNSFFYNANSQFTGELHSERTKDIDGISVPFEPY
                     RAPYSLVLRRTDSSNEYLVSGDDGRSTYTRGAHYKMPRFFNTKAKITESNYDKPTQDL
                     DFIADMSGQAVEVAITFDKPYLLSDIVKLVPDQLKLNWIWIGTESSYDTSGLFPANLY
                     GFKPDWKANMTYKEQKQLDEKINNILKKDNEADLSKLNAAYDKPVTPTVALQNSYDTF
                     RHYLQEAVDNHWINNTYGDANGTHLSEQEDVALFLKNNRNVKTAKFAGIILTGKAEQF
                     ASLKTADWIYASNIGQSVTIQPYHQLTK"
     gene            complement(4787..5257)
                     /locus_tag="TVR04_001556"
     CDS             complement(4787..5257)
                     /locus_tag="TVR04_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1270233.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALSPEKI
                     RAWMYRVAVRKYIDQYRRDKAYLDILQRDFFHQERVVEFDQPNYEPLYTAVNELPEKY
                     RWVLSLYYFQDLSVKEVASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFK"
     gene            5613..5822
                     /locus_tag="TVR04_001557"
     CDS             5613..5822
                     /locus_tag="TVR04_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270234.1"
                     /translation="MSSLSRKHEQIHHQRKLAKPSQSQFAELLETNKQTLSMTENGQR
                     KAPIKKLIMLHNIFGVTANELLPKD"
     repeat_region   6185..7341
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6251..6286
                     /rpt_unit_seq="gttttggaaccattcaatacagcataactctaaaac"
     gene            complement(7617..8294)
                     /gene="csn2"
                     /locus_tag="TVR04_001558"
     CDS             complement(7617..8294)
                     /gene="csn2"
                     /locus_tag="TVR04_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEL1270235.1"
                     /translation="MMINFSLLDEPLKLEQMTILTVKDVRVFSSLIRNFYQYGESGDL
                     KLFDHRLKGLKETELMIITDILEYDINSPTILKMVHADLEECFNEQPEVKSMLEKLAA
                     TITELIAFECLENELDLEYDKITILELIKALGVKVETQSDTIFEKCLEILQVFKYLTK
                     KKLLVFVNSGSYFTREEFEQLKEYVELSNQTVLFLEPRPLYDFPQYILDEDYFLVTQN
                     KLEGIEH"
     gene            complement(8284..8628)
                     /gene="cas2"
                     /locus_tag="TVR04_001559"
     CDS             complement(8284..8628)
                     /gene="cas2"
                     /locus_tag="TVR04_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEL1270236.1"
                     /translation="MSYRYMRMILMFDMPVDTVEERKAYRKFRKFLLSEGFIMHQFSV
                     YSKLLLNNTANNAMIRRLREQNPQKGNITLLTVTEKQFARMIYLHGEKNASIANTDKR
                     LVFLGEAYSGDD"
     gene            complement(8625..9494)
                     /gene="cas1"
                     /locus_tag="TVR04_001560"
     CDS             complement(8625..9494)
                     /gene="cas1"
                     /locus_tag="TVR04_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEL1270237.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHFIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLIKRLVDNNSLVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMAWSEELK
                     ADVWTQIIAQKMLNQSCYLGQCSYFEKSQAIMNLYHDLKSFDPSNREGHSARIYFNAL
                     FGNQFSREQDCDINAGLDYGYTLLLSIFAREVVICGCMTQFGLKHSNQFNQFNFASDL
                     MEPFRPIIDRIVYDNRHKTFVQIKRQLLSIFSETYPYNGKEMYLSNIVSDYTKKVIKA
                     LNNEGEGVPEFRI"
     gene            complement(9494..13540)
                     /gene="cas9"
                     /locus_tag="TVR04_001561"
     CDS             complement(9494..13540)
                     /gene="cas9"
                     /locus_tag="TVR04_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEL1270238.1"
                     /translation="MKKPYTIALDIGTNSVGWVVVTDDYRVPTKKMKVLGNTERKTIK
                     KNLIGALLFDSGDTAEGTRLKRTTRRRYTRRKNRLRYLKEIFTEEMAKVDDGFFQRLE
                     DSFYVLEDKEGNKHPIFANLADEVAYHKKYPTIYHLRKELVDNPQKADLRLIYLAVAH
                     IIKFRGHFLIEGTLSSKNNNLQKSFDHLVDTYNLLFEEQRLLTEGINAKELLSAALSK
                     SKRLENLISLIPGQKKTGIFGNIIALSLGLTPNFKANFGLSKDVKLQLAKDTYADDLD
                     SLLAQIGDQYADLFLAAKNLSDAILLSDILTESDEITRAPLSASMVKRYREHHKDLVT
                     LKTLIKDQLPEKYQEIFLDKTKNGYAGYIEGQVSQEEFYKYLKPILARLDGSEPLLLK
                     IDREDFLRKQRTFDNGSIPHQIHLEELHAILRRQEVFYPFLKDNRKKIESLLTFRIPY
                     YVGPLARGHSRFAWVKRKFDGAIRPWNFEEIVDEEASAQIFIEKMTKNDLYLPNEKVL
                     PKHSLLYETFTVYNELTKVKYATEGMTRPQFLSADQKQAIVDLLFKTNRKVTVKQLKE
                     NYFKKIECWDSVEITGVEDSFNASLGTYHDLLKIIQDKDFLDNPDNQKIIEDIILTLT
                     LFEDKKMISKRLDQYAHLFDKVVLNKLERHHYTGWGRLSGKLINGIRDKQSGKTILDF
                     LKADGFANRNFMQLIHDSELSFIDEIAKAQVIGKTEYSKDLVGNLAGSPAIKKGISQT
                     IKIVDELVKIMGYLPQQIVIEMARENQTTAQGIKNARQRMRKLEETAKKLGSNILKEH
                     PVDNSQLQNDKRYLYYLQNGKDMYTGDDLDIDYLSSYDIDHIIPQSFIKNNSIDNKVL
                     TSQGANRGKLDNVPSEAIVRKMKGYWQSLLRAGAISKQKFDNLTKAERGGLTQVDKAG
                     FIQRQLVETRQITKHVAQILDSRFNTEFDDHNKRIRKVHIITLKSKLVSDFRKEFGLY
                     KIRDINHYHHAHDAYLNAVVAKAILGKYPQLAPEFVYGDYPKYNSFKERQKATQKTLF
                     YSNILKFFKDQESLHVNSDGEEIWNANKHLPIIKNVLSIPQVNIVKKTEVQTGGFYKE
                     SILSKGNSDKLIPRKNNWDTRKYGGFDSPTVAYSVLVIAKMEKGKAKVLKPVKEMVGI
                     TIMERTAFEENPVVFLEARGYREIQEHLIIKLPKYSLFELENGRRRLLASASELQKGN
                     ELFLPVDYMTFLYLAAHYHELTGSSEDVLRKKYFVDRHLHYFDDIIQMINDFAERHIL
                     ASSNLEKINHTYHNNSDLPVNERAENIINVFTFVALGAPAAFKFFDATIDRKRYTSTK
                     EVLNATLIHQSVTGLYETRIDLSQLGEN"
BASE COUNT         4426 a         2836 c         2260 g         4142 t
ORIGIN      
        1 taagattttc ccaaacctat ttatcatttc taggattaaa gaaaataaat attgacatat
       61 tctgattttt taatattatg gaataagaga gacaaaatag tcaaaaagga ggggtaggat
      121 ttttagcacc ataacaatat catcaccata gcatcaagag ctaaggaggg taaatagtct
      181 ttctatttta tagtatttgc gagtatagtt ttaaggctag ctattctttt cccagagttt
      241 tgaatcactt tattttattg taaaaggact ttataacgat gaaactaaag aaaataatag
      301 cactagcatg tgttggaata ttaacattac atcagctctc tccagcaatt gtttatgcaa
      361 ctactgatgc ttctgatgga acagctgcta cagttaatgc aggtgataca gctgctcctt
      421 ctgccgaggc taagccatca caactgatga ctgataccca agccttattt acagataact
      481 cttgcagtaa gctggcaagt ggtgtcacac aagaaaaaat agatacctta aagcaaaagg
      541 cgactgactc aacagagcct gaaaaagagc aaatcctagg tctactagat aaggcagcta
      601 gcctattaca acagtttacc ctacaagggt taggcaatgg tgtctttgct caactttact
      661 tctatgctga tggcagctac actgcaagtt tggtcactaa aaggggccaa cctcactctt
      721 atttctctac taattacgct acgataacga ttcttaataa caagaaggaa accgtctatt
      781 caaaagaata cgctggcaat gtttctcagg tagcacaaac agaagagctt gagctaaaag
      841 aaggctatta cctcatcatc aataagcagg agcctaaccg cttctacact aaccacaatg
      901 acgctctaaa gcaaaacaat accaaccctt acacttatgt ggtgagagat gggcagcttg
      961 agcgtattga tgacagcaat agaacgctgc gcttccttgg cttaggcaat gcagaatacg
     1021 caaccttaag ggttgattac aatgcctcta ccctaaccct caaaaccaag cagaccaagc
     1081 cacatgttta cttcagtggg tcttatgaaa agcttgaggt gctggataca gaaaatcaag
     1141 taatctacac aaaggacttt attggaactc aagtcctcga agctaaaaca gagactattc
     1201 cttttaaagt aggctacaag atccgcttga caggtagtga gcaccatacc agagtgaaat
     1261 tctacgatga ttatgcggta gaagcgccat taacactctc taaaaatcaa gcaaccttaa
     1321 agcttcttga ccactcacta gagctaatga ggtctaaaac aggctcagag cttgagtctg
     1381 aggtactgac tctatttaca gatgagtcta caagtaagct agcaagtggt gtcacacaag
     1441 aaaaaataga tgctcttagg aaaaaggcga ctgcctcaac agagcctgaa aaagagcaaa
     1501 tcctaagcct actggataag gcagctagcc tattacagca atttacccta caagggctag
     1561 gaaatggtgt ctttgctcag ctctacttct acgctgatgg cagctacact gcaagcttag
     1621 tcactaaaaa aggacagcca cactcttaca tcgctaacaa ttacgctacc ctaaccattc
     1681 tcaatgacaa aaaagaaacc gtttatgcta aggaatacgt gggtaatgtt tcccaaacag
     1741 ctaaaacaga aagccttact ctcaaggaag gctattacct agtcatcact aaacaggagc
     1801 ctaaccgctt ctacactaac cacaatgacg ctctaaagca aaacaatacc aacccttaca
     1861 cttatgtggt gagaaacggg cagcttgagc gtattgatga gaaaaataga accctacatt
     1921 tccttggctt aggcaatgca gaatacgcaa ccttaaaggt tgactacaat gcctctacct
     1981 tgacactcaa gaccaaaaag actaagccac atgtttactt cagtgggact tacgaaaagc
     2041 ttgaggtctt agacttaaaa gacaaggttg tctacacaca agactttatc ggaaaccaag
     2101 ttctaacagc taaaacagag actattccct tcaaggtggg ctacaagatt cgcctaactg
     2161 gtagtgagca ccatactaga gtcaaagcct atgatgaaga aaacaaggct gtttctctta
     2221 gtctccctaa aaataaggca gagattcgaa tcaccaaggg tggtttggct tctgtatttg
     2281 cactagaggc taaagctact aatacactcg tacaagccgt tgaaaaaaga ctaaccaagg
     2341 aaaaaatcga ggacttcaag aagaaagaca acaagcataa agcctttatt gattggttgc
     2401 tcaaagataa tgaagccatg caattgtatc ttggcgcagg ctatgcccat tctgcagcac
     2461 agggtggcat gtcatcatac caattcaaaa atacctataa cctcaccaat gaactagaag
     2521 cattggaatt gtggtttaag atttgggata aatacaaagc ctcacatcaa ggtattcaac
     2581 tcaaaatggc tattgcggtt gccttggaat ttaccaagcc tgtgggcgct tggtacaatg
     2641 agagccaaaa gattgatcct cttgaaagat ttgtaacctt tgcagaggcc gagcaaggca
     2701 atgtcttatt tgaagatttt tacagcttaa ctgttgagca aatccgaaat gtcgtcaatg
     2761 ccaaaattac tgatgaggac atgaaatggc taagacaata cgttgaaacc aataagcctg
     2821 ctatgattaa ccgtaatgac atcactaagg gctattcgct aatcagttat gtcgggacca
     2881 acccagaaac aggtgtgagc gtccacagct ctggctttta cggaccaaat ccaaccatca
     2941 aggaagtcat caaatatggt ggtgtctgcg gtgccatgtc taaattaagt agtgtgctag
     3001 cacaggctta cggtgtgcca gcctttccga ttggacaacc aggtcactgt gcttatatct
     3061 acttaaatgc tgaccatacc tatcagctcg gctatgatgt ctcaggctgg acaggctgtg
     3121 gtaactacaa cacaacactt ccttatgtcc aaattcataa cgtctactct cttaatatag
     3181 acgcttataa tgcctcagaa tatgaacgat ataaggctga agcagctact gacaaggaga
     3241 ctaagcttaa tcatttagat gctgctctaa aggcagagcc attaaactat aaagcatgga
     3301 atgacaagct agcattggta gcttcagacc aaacagcata ccaaagcact ctaaatgaca
     3361 tgaagtctgc attgaaggat tatccagtta ttatcaataa tttagaaaaa gatactaaac
     3421 agtaagctaa ttccttgggc ttaaaagaag gctagctaaa actatactta caaatactat
     3481 aaaatataag agtctcagct tgaaggacat gctcaattga gagagctgct tcaagctttt
     3541 ttgattgcag caaagcaaaa agccccagaa gcagtgatca aacactgacc tccaagagcc
     3601 ttttgacgtc ttttgaccta agctggagct tttttaagca tcgattgctt gacttaatct
     3661 tttaagcttt tatcctttgc ctgatgcgct tgattgtcag cacaagcttt ttatttactt
     3721 agttagctga tgatagggct gaatggtaac agactgacca atatttgaag catagatcca
     3781 atcagccgtt tttaaggagg caaactgctc agccttgccg gttaaaataa tgccagcaaa
     3841 cttagctgtt ttgacattgc gattgttttt tagaaataag gccacatcct cctgctcact
     3901 taaatgagtt ccattagcgt cgccataggt attattaatc cagtgattgt caactgcctc
     3961 ctgtagataa tgcctgaagg tatcatagga attttgcaga gccaccgtcg gggtaactgg
     4021 cttatcgtaa gcagcattaa gcttagacag atcagcctcg ttgtcctttt ttaggatatt
     4081 gtttattttt tcatctaact gcttttgctc cttgtacgtc atattggcct tccagtctgg
     4141 cttaaagcca tataaattag cagggaaaag ccctgaggtg tcatagctgc tttctgtgcc
     4201 aatccagatc caattcagct ttagctggtc tggaaccagc ttgactatgt ccgataataa
     4261 ataaggctta tcaaaggtaa tggctacctc aaccgcctgt cctgacatgt cagcaataaa
     4321 gtctaggtcc tgcgttggct tgtcataatt gctttctgtg atcttggcct tagtgttgaa
     4381 gaagcgaggc attttataat gtgcgcctct tgtataagtt gaccgtccat catcacctga
     4441 aacaaggtat tcattgctgg aatcagttcg gcgtaaaacc aaggaataag gagctctata
     4501 gggctcaaac ggcaccgaaa tgccatcaat gtccttggtt cgctcagaat gaagctcacc
     4561 agtaaactgc gaattggcat tgtaaaagaa gctattaaca tcaatattag gataagcaat
     4621 ttgtatacga ttgttgtaat aagccatcaa atactgaccg tttatgcttg tcaatcgatt
     4681 taatcccata tagcccagca caagagctac taaggctaag ccagcactca acactacata
     4741 tttaagagtc agtctccttt tatggcgctt agcaatggct tcaaaatcat ttgaaatcgt
     4801 cataggtata acctgctttc tttagttttt ctttaaggca tcgtcttccc cgcatcaagt
     4861 tgaccttgac gctgctaaca gaccaatgga gcaaagatgc cacctccttg actgataggt
     4921 cctgaaagta ataaagcgat agaacccagc ggtatttttc tggcaattca ttgactgctg
     4981 tatagagcgg ctcatagttg ggctggtcaa attcaacaac cctctcttga tgaaaaaagt
     5041 ctctttggag aatatccaag taagccttat cccgcctgta ttggtcaatg tattttctaa
     5101 cagcgacccg atacatccag gcacgtattt tttcaggaga tagagcaagg tcactctcaa
     5161 gcatttttaa caaaacgtct tgactaatat cacgcgctag ctccttagca acacctgatc
     5221 tcactaggta ggcaataatt tccttagaat aagccactag ctctctttca taagcatcta
     5281 acctaatgat cctcccctcc cttcttcacc tatataacga acaactgctt catttggtta
     5341 caaaaaaatc cccaaatgga gattttggct ctatcatttc tgtagtgggt aaatccacca
     5401 tggagattat agggcttttt gggcatcaaa aaagtcccat aagacttatc atgaaaagcg
     5461 accaaacaac tcattagaaa ggctcatatg aaagacctta agaataccac agaatcgctc
     5521 ggaataaaag ataaacatat cacagtactc tctgctggaa agcatcacac tcacatcgtt
     5581 atcaaggcta agcaggatca tgagcctctg ccttgtcctc gctgtcaagg aagcatgagc
     5641 aaatacacca ccaaagaaag cttgctaaac caagtcaaag tcaatttgct gagctactag
     5701 aaaccaacaa acaaactctc agtatgacag aaaatggcca gcgcaaagct ccaatcaaaa
     5761 agttaatcat gctgcataac atttttggtg taacagcaaa cgagctattg ccaaaagatt
     5821 gacaatcgtt tgataaatca cagattaaac agaccagttc attctatggt cattttctgc
     5881 cagtagtagg gtagaaaaat aaaagtaagg gtaatttcct caacaaccac tacatcaaac
     5941 atatcttacc tgaaaatatt gattaacctg accgacaacc taagctatcg caagcataaa
     6001 tcccctttgg tggggaaagg gaagttacag ttcccttaat ttgtccccat tatgccagca
     6061 gaaaagaggc catacaatga caatcactat cgtagtatta cccatcatta gcaatcgtta
     6121 cttgcttaat agcaagcatg aagaccaatt actactgcaa ctgttacctt ttaatcattt
     6181 acggatatta aaactattca aaacagcata actctaaaac ataaaaggat ctagaataac
     6241 agctcctttg gttttggaac cattcaatac agcataactc taaaactagc gtggatgggc
     6301 ttaaaagagg gccacggttt tggaaccatt caatacagca taactctaaa actcaataca
     6361 gcagcaacac tcacaagcac cagttttgga accattcaat acagcataac tctaaaactg
     6421 tgtcatgata cggaaagtag ctctagtcgt tttggaacca ttcaatacag cataactcta
     6481 aaacattagc attcgtgcgt tggcattatg ataagttttg gaaccattca atacagcata
     6541 actctaaaac tagctataca gtaaacgaag atgggtcaat gttttggaac cattcaatac
     6601 agcataactc taaaacaggc tgatgtcgga gcatcagtgg aggcaagttt tggaaccatt
     6661 caatacagca taactctaaa actcgttggc ctcgagctcc acaaaatcct gagttttgga
     6721 accattcaat acagcataac tctaaaactg aacctattat ctctgaggaa gtctttaagt
     6781 tttggaacca ttcaatacag cataactcta aaactaccca tttcataccc aaaaatatgc
     6841 aagtgttttg gaaccattca atacagcata actctaaaac atgcttctaa accaaggtca
     6901 acaggagaaa gttttggaac cattcaatac agcataactc taaaaccgct catttagttc
     6961 tactgcatat tccaaagttt tggaaccatt caatacagca taactctaaa actacgtaga
     7021 caacgataaa attcgcgtgg cgttttggaa ccattcaata cagcataact ctaaaactat
     7081 atatcaggtt tagaaactgc gtttctagtt ttggaaccat tcaatacagc ataactctaa
     7141 aaccctgaga ttgttcttta aacgataaaa gtagttttgg aaccattcaa tacagcataa
     7201 ctctaaaact aaagggatag tcgttacacc tttctgatag ttttggaacc attcaataca
     7261 gcataactct aaaacaacct gtataaatgt tgtggtacgt aaccagtttt ggaaccattc
     7321 aatacagcat aactctaaaa cctcgtagac catcttttgc tataagacgt cattatcaga
     7381 ttatttgtcg tggctaaact tcaattgcaa ataatctttg aactatcaag attataactc
     7441 aagaagtata ttatctcaat ggtttcccct atcccaagcc attttgttat cgtcaatctt
     7501 taatttacca gctatgatac atgattaatc caactttcat ctacttagag agcttaacta
     7561 accgctacct gactggacgg ttgatttcta agagaacata aacacttacc ctatccttaa
     7621 tgttcaatac cttctaactt attttgtgta actaaaaaat aatcttcatc taaaatatat
     7681 tgtgggaagt catacagagg tcttggctct aaaaagagaa cagtttgatt tgacaattca
     7741 acatattctt ttagttgctc aaattcttct ctagtaaagt aggagccact gttaacaaaa
     7801 actaataatt tcttttttgt gaggtattta aacacctgta aaatttcaag gcatttttca
     7861 aaaatagtgt cactttgtgt ttcaaccttc actcccaaag cctttattaa ttccaaaatg
     7921 gtgatcttgt cgtattctaa atccaactca ttttctaaac attcaaaagc aatcaactct
     7981 gttattgttg ccgctaattt ttcaagcatt gatttaactt ctggttgctc attgaagcac
     8041 tcttccaaat cagcatgaac catttttaag atagttggtg aattgatatc atactccaaa
     8101 atgtctgtaa tgatcatcaa ctcagtctct tttaaacctt ttaaccgatg gtcaaataat
     8161 ttcagatcac cagattcccc atactgataa aaattcctta tcaaagagga aaatacccta
     8221 acgtccttca ctgttaaaat tgtcatttgt tcaagcttta aaggttcatc taaaagcgaa
     8281 aaattaatca tcaccactat aagcctcccc taagaatacc aaccgcttat ctgtattagc
     8341 aatagatgca tttttctcac catgtaaata gatcatacga gcaaactgtt tttccgtcac
     8401 cgttaataaa gtaatatttc ctttttgggg attctgctct cgtaaacgtc ttatcatagc
     8461 attattagct gtattattca gcaatagttt actataaaca gaaaactggt gcatgatgaa
     8521 tccttcactc aataaaaatt ttctaaattt ccggtaagct ttacgctcct ctaccgtatc
     8581 aacaggcata tcaaacatca aaatcattct catataacga taactcatat cctaaactca
     8641 ggaactcctt ccccttcatt gttaagtgcc ttaataacct ttttagtata gtcactaaca
     8701 atatttgata agtacatctc tttcccgtta taaggataag tctcagaaaa tatagacaat
     8761 agttgacgtt taatctgtac gaatgtctta tgacggttgt catagacgat tcgatcaata
     8821 atcggtcgaa atggctccat tagatcactg gcaaaattaa attgattgaa ttgattggag
     8881 tgcttaagac caaactgagt catacaacca cagataacca cctcacgcgc aaatatgcta
     8941 agtaagaggg tatagccata atctaatcct gcattaatat cacaatcctg ttcacgtgaa
     9001 aactggtttc caaacaaggc attaaaataa attctcgcag aatgtccttc gcgattactc
     9061 ggatcaaagc tttttaaatc atgatataaa ttcataatag cttgagattt ctcaaaataa
     9121 gagcattgcc caagataaca ggattgattt aacatttttt gagcaataat ctgggtccaa
     9181 acatcagctt taagctcttc tgaccaagcc atttgtctgc taagctgcaa gctggaatca
     9241 tgtctggcat agtaaggcat cagcatagca gttggtaaac gcttgtcatc acaaaaaatc
     9301 actaagctat tgttatcaac caatcgctta attagcatag tagacaacac aatatccgtt
     9361 gtctctaata ataaaatatc aatctctgat aaatgaatta attctgtctt ataagcatcc
     9421 ttaaaaataa aatgattatt tttataagat aatttagagt gtgtattaac tacaaccgta
     9481 cgccatcctg ccattagttc tctcctaatt gactcaaatc aattcgcgtc tcatacaaac
     9541 cagtaacaga ttgatgaatg agagtggcat ttagcacttc cttagttgag gtatatcgtt
     9601 ttcgatcaat agtcgcatca aaaaatttaa aggctgcagg tgctcctagg gctacgaaag
     9661 taaacacatt aatgatattc tctgctcttt cattaactgg aaggtcagaa ttattgtgat
     9721 atgtatggtt tattttctct aaattactac tagcaagaat atgacgctct gcaaaatcat
     9781 taatcatttg aataatgtca tcaaaataat gcaaatgcct atctacaaaa tattttttcc
     9841 tcaaaacatc ctctgaggat ccagttagct catggtaatg agcagctaaa tatagaaatg
     9901 tcatataatc aactggaaga aacaattcat ttcctttttg tagttcacta gcacttgcca
     9961 ataaacgtct tcttccattt tctaattcaa acaagctata tttagggagt tttataatga
    10021 gatgctcttg aatttctcga tagcctcttg cttctaaaaa gactacagga ttttcttcaa
    10081 atgcggtcct ctccataatg gtaataccaa ccatttcctt cactggcttt aatacttttg
    10141 cttttccctt ttccatttta gctatcacca aaacagaata agctacagtt ggactatcaa
    10201 agccaccata cttcctggta tcccagttat ttttccttgg gatcagctta tcagaattac
    10261 ccttagacaa aatggactct ttatagaagc cccctgtttg tacttccgtt ttcttgacga
    10321 tattaacctg cggaatcgaa agaacatttt taataatagg taaatgctta ttggcattcc
    10381 atatttcttc accatcagag ttaacatgaa gactttcttg atctttaaag aattttaaga
    10441 tatttgaata gaataacgtc ttttgagttg ctttctggcg ttccttaaag ctattatatt
    10501 tggggtaatc tccataaaca aattctggag ctagttgagg atacttacct agtatcgctt
    10561 tggcaacaac agcattaagg tatgcatcat gagcatgatg ataatgattg atatcacgaa
    10621 ttttatacaa accaaactct ttacggaaat cagaaaccag ctttgatttt agcgttataa
    10681 tatgaacctt tcgaatacgc ttattatgat catcaaattc agtattgaag cgactatcta
    10741 agatttgtgc cacatgtttt gtgatttggc gtgtctccac taattgacgt tggataaagc
    10801 cggctttgtc tacttgagtt aaacctccac gttctgcttt tgtcagatta tcgaattttt
    10861 gctttgagat agctcctgct ctcaataagg attgccaata gcctttcatt ttcctaacaa
    10921 tagcctcact aggaacatta tctaattttc ctcgattagc gccttgtgag gttaatacct
    10981 tgttatcaat ggaattattc ttaataaagc tctgcggaat gatatgatca atgtcatagc
    11041 tactcaaata atcaatatct aagtcatcac ccgtatacat atcctttcca ttttgaagat
    11101 aatagaggta acgcttatca ttttgcaatt gactattatc aacagggtgc tccttcagaa
    11161 tattgctacc caattttttg gcagtctctt ctagctttct catgcgttga cgagcatttt
    11221 taattccttg agctgtagtc tgattttcac gtgccatttc aataacaatc tgctgcggga
    11281 gatagcccat gattttgacc agctcatcaa cgattttaat tgtttgtgaa ataccttttt
    11341 taatagccgg actacccgct aaattcccaa ccaggtcttt cgaatactca gtttttccaa
    11401 tcacttgggc tttagcaatc tcatctataa agcttagttc actatcatga attaactgca
    11461 taaagtttcg attggcaaaa ccatcagcct ttagaaaatc taaaattgtt tttcctgatt
    11521 gtttgtctcg aataccattt ataagctttc ctgataaacg cccccaaccg gtatagtgat
    11581 gcctctccag tttattcaat acgactttat caaagagatg tgcatattga tctaatcgtt
    11641 ttgaaatcat ttttttatct tcaaaaagtg ttaaggtcaa aataatatct tcaatgattt
    11701 tctggttgtc aggattatct aaaaaatcct tatcctgaat gatttttaac aagtcatgat
    11761 aggtcccaag tgaagcattg aagctatctt caaccccagt aatctcaaca ctatcccagc
    11821 actcaatctt tttaaaatag ttctctttta attgtttaac agtcacttta cgatttgttt
    11881 tgaacaataa gtcaacaata gcttgtttct gatcagcaga taaaaattga ggacgtgtca
    11941 ttccttcagt agcatatttg acctttgtta gctcattata aactgtaaaa gtttcatata
    12001 ataggctatg cttaggaaga accttttcat ttggcaagta gagatcattt ttagtcattt
    12061 tttcaataaa gatctgtgcg gaagcttctt catcaacaat ctcttcaaaa ttccagggtc
    12121 taatagcccc atcgaatttt cgctttaccc atgcaaagcg actatgacca cgagccaacg
    12181 gacccacata ataaggtatt ctaaacgtta aaagagattc aattttcttt ctattatctt
    12241 ttaaaaatgg gtagaagact tcttgtcttc tcaaaatagc gtgtaattct tctaaatgaa
    12301 tttggtgagg aatagagcca ttatcaaagg ttcgttgctt tctcaaaaag tcttctcggt
    12361 caatttttag aagtaacggt tccgatccat ccaatcttgc taaaataggc ttaaggtatt
    12421 tgtaaaattc ctcctggcta acttgtccct caatatatcc agcataacca tttttagtct
    12481 tatctaaaaa aatttcctgg tacttctccg gtaactgatc ctttattaat gttttcaaag
    12541 tgaccaagtc cttgtgatgc tcacgataac gttttaccat agacgctgac agaggtgctc
    12601 tagttatctc gtcactttct gtcaaaatat ctgacaaaag aatggcatct gataaatttt
    12661 tagccgctaa gaataaatca gcatactgat ctccaatttg agccagtaga ctatccaaat
    12721 catcagcata ggtatcctta gccaactgta atttgacatc cttacttaaa ccaaaattag
    12781 ctttaaaatt tggtgttaat cctagcgaga gtgcaataat attaccaaaa atacccgttt
    12841 tcttttgtcc aggaatcaga gaaatgagat tttctaaacg ctttgactta cttaatgctg
    12901 cagacaacag ctctttggca ttaatgcctt cagtaagcaa tcgttgctcc tcaaacaata
    12961 gattataggt atccacaaga tgatcaaatg atttctgaag attattattc tttgaactta
    13021 atgttccctc aatcagaaaa tgtcccctaa acttaataat atgcgctact gccaaataaa
    13081 ttaagcgtaa atctgctttt tgaggattat ctactaactc ttttcgtaaa tgataaattg
    13141 ttggatactt tttatgataa gcaacttcat ctgctagatt agcaaaaatc ggatgcttat
    13201 ttccctcctt atcctctaaa acatagaatg aatcctccag tcgttgaaag aaaccatcat
    13261 ctacttttgc catttcctca gtaaaaattt ctttaaggta acgtagtcta ttctttcttc
    13321 ttgtatatct gcgacgggtc gttcttttta agcgagttcc ctctgcagta tcaccactat
    13381 caaataataa ggcaccaatc aaatttttct taatggtttt tcgctctgta tttcctagta
    13441 ccttcatttt ctttgttgga accctataat catccgtcac aacaacccat cctacactat
    13501 tagtaccaat atcaagagca atagtataag gttttttcat aaaaagtctc ctttttgaaa
    13561 tagactaacg atttccctag caagcaaggc attcattttc tttttattta taattttcta
    13621 aatattgtat accaagatat aatactaatt ataactctat aata
//
LOCUS       DARYSY010000053        13202 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYSY010000053 DARYSY010000000
VERSION     DARYSY010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13202
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..812
                     /gene="glmU"
                     /locus_tag="TVR04_001562"
     CDS             <1..812
                     /gene="glmU"
                     /locus_tag="TVR04_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516067.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1270239.1"
                     /translation="AQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVNDRLALAQA
                     EVIMQERINRQHMLNGVTLQNPAATYIESSVEIAPDVLIEANVTLKGQTRIGSRSVIS
                     NGSYILDSRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDECVHIGNFVEVKG
                     SHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGSHAFIGSHSTLI
                     APVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAN"
     gene            843..1397
                     /locus_tag="TVR04_001563"
     CDS             843..1397
                     /locus_tag="TVR04_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1270240.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1397..1645
                     /locus_tag="TVR04_001564"
     CDS             1397..1645
                     /locus_tag="TVR04_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270241.1"
                     /translation="MGKPLLTDDIIEKARRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            1669..2370
                     /locus_tag="TVR04_001565"
     CDS             1669..2370
                     /locus_tag="TVR04_001565"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1270242.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELI
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAHTAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPNDN"
     gene            complement(2420..3067)
                     /locus_tag="TVR04_001566"
     CDS             complement(2420..3067)
                     /locus_tag="TVR04_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1270243.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MISQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGVFRLSRVHD
                     HFELIQYLEAHQLTVNSEFRLIQIDDFAKTYTIAYADKELIIPENIAKQLYVTAI"
     gene            3213..4145
                     /locus_tag="TVR04_001567"
     CDS             3213..4145
                     /locus_tag="TVR04_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1270244.1"
                     /translation="MKKKFSLALSAFLAVFMLVACSNGGHKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKKKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            4204..4929
                     /locus_tag="TVR04_001568"
     CDS             4204..4929
                     /locus_tag="TVR04_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1270245.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLDQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKELKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            4930..5763
                     /locus_tag="TVR04_001569"
     CDS             4930..5763
                     /locus_tag="TVR04_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1270246.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAVTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(5919..6725)
                     /locus_tag="TVR04_001570"
     CDS             complement(5919..6725)
                     /locus_tag="TVR04_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1270247.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEA
                     AAKAYEAKIKKALKADADQFPQLNKEVGKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSTDNYPKPIIDAYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(6812..6985)
                     /locus_tag="TVR04_001571"
     CDS             complement(6812..6985)
                     /locus_tag="TVR04_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270248.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAVVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            7105..9504
                     /locus_tag="TVR04_001572"
     CDS             7105..9504
                     /locus_tag="TVR04_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1270249.1"
                     /translation="MARRTQRKKNSPKKRLTKAELEKQKAIKRMIVSFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLILAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLSREALEEQEYLANQAIDPETGELLAEPADSSAEAISSKEPEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQSKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDHGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            complement(9710..10060)
                     /locus_tag="TVR04_001573"
     CDS             complement(9710..10060)
                     /locus_tag="TVR04_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1270250.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(10224..11021)
                     /locus_tag="TVR04_001574"
     CDS             complement(10224..11021)
                     /locus_tag="TVR04_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1270251.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIEGVSKGNILVID
                     DTVNHILNKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            11258..11683
                     /gene="rplK"
                     /locus_tag="TVR04_001575"
     CDS             11258..11683
                     /gene="rplK"
                     /locus_tag="TVR04_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1270252.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            11789..12478
                     /gene="rplA"
                     /locus_tag="TVR04_001576"
     CDS             11789..12478
                     /gene="rplA"
                     /locus_tag="TVR04_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1270253.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(12840..>13202)
                     /locus_tag="TVR04_001577"
     CDS             complement(12840..>13202)
                     /locus_tag="TVR04_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270254.1"
                     /translation="PRGENPTPTPDPMPQPMPDPAPKPMDPKPESKPEPKPTPQPETK
                     PQSKPAPQSEAKPQSKPAPQSEAKPQKPTKPSNATSQSNGKSLPKTNDTGSLSTVLGT
                     GLLSLLGLGFLTRRKRKQ"
BASE COUNT         3744 a         2489 c         3086 g         3883 t
ORIGIN      
        1 atgcccaagg ggagtactac ctaaccgatg tgatcagtat tttcaaggct ggccaagaaa
       61 gggttggcgc ttacctgctg aaggactttg atgagagcct aggggttaat gatcgcttag
      121 ctctagccca ggccgaggtg attatgcaag agcggatcaa caggcagcac atgcttaatg
      181 gggtgaccct gcaaaacccg gcagctacct atattgaaag cagtgtagag attgcaccag
      241 acgtcttgat tgaagccaat gtgaccttaa agggacagac taggattggc agcagaagtg
      301 tcataagcaa tgggagctat atccttgatt caaggcttgg tgagggcgta gtggtgagcc
      361 agtcagtgat tgaggattca gtcctagcag atggcgtgac agtagggcct tatgcacaca
      421 ttcgcccgga ctcccagctc gatgagtgtg ttcatattgg gaactttgta gaggttaagg
      481 ggtctcatct aggggccaat accaaggcag ggcatttgac ttacctgggg aatgccgaga
      541 ttggctcaga ggttaatatt ggtgcaggaa gcattacggt taattatgat ggtcaacgga
      601 aataccagac agtgattggc agtcatgcct ttattgggag tcattcgact ttgatagctc
      661 cggtagaggt tggggagaat gctttgacag cagcagggtc tacgatagcc cagtcggtgc
      721 cggcagacag tgtggctata gggcgtagcc gtcaggtggt gaaggagggc tatgccaaga
      781 ggctgccgca ccacccaaat caagcaaact aaaatgatgg agagaaagca aggagatcag
      841 gcatggattt tgaagaaaaa acgattaaaa ggcaagagat ttttgatggt cacattttca
      901 aagttgcggt agatgatgtc caattaccaa acggtctagg tcaggctaag cgcgaattga
      961 tttttcatcg cggtgcagtc gctatattgg ctgtaacgcc agagcgtaag ctgttaattg
     1021 tcaagcagta ccgtaaggct atcgaagcga tttcttatga aattcctgct ggaaaactag
     1081 aggtcggtga ggccaactca gcattagaag cagcagcacg agagctggag gaagaaaccg
     1141 cctattctgg tgatttgcgt cttattcacg agttttatac agcgattggt ttttgtaatg
     1201 aaaaaattaa gctgtacttg gcgacagacc tgcagagagt tgccaatcct agaccacagg
     1261 acgcagatga ggtgattgag cttcttgagc tgagctatca agaatgtatg gatctagtgg
     1321 cacaaggaaa gcttgtcgat gctaaaacca tcattgccct gcaatattac gcccttcatt
     1381 ttggaggtga tgtgtaatgg gcaagccctt gctgactgat gacattatcg aaaaggctcg
     1441 gcgcggagaa cagtttgagc ctgacgatta tgcagatttt gaaaccaaaa tcatgacctt
     1501 tgaggataag catactgatc gtatttacaa aagtcgcaga attgaaaatg caaagcgcag
     1561 tcgctttcaa tcgcggttaa atctgattct cttagcggtg cttgtcttga ttgctctctt
     1621 ggtttatgcg gtctttaatt tatagaaaaa aacaaataag gatatcatat gaaaattgga
     1681 attattgcgg ctatggaaga ggagctgcgg tttttattgg agcagctcca cgatagtcaa
     1741 gagcatcagg tgctttccaa tacctactat acaggtcgtc ttggtcgtca tgagctgatc
     1801 ttagtccaat ctggtgttgg aaaggtcatg tcagcgatga cagttgcgat gctagcagag
     1861 cattttcagg ctgacgctat tataaataca ggatcggctg gagcaatagc tagtggcttg
     1921 gctattggtg atgttgttgt tgctgatcgc ttggtgtatc atgatgtgga cgtgacggcc
     1981 tttggctatg actatggtca aatggctgcg cagccccttt actttgacag tgatagcaag
     2041 ctggttgaga cctttaagca ggtgcttgat caggaaaaga ccaatagtcg gattggcttg
     2101 attgcaacag gagatagctt tattgccggc caagacagta ttgataccat caaagcacat
     2161 ttcccagaga ccttagcagt ggaaatggag ggagcagcag tggcacaggc cgctcatact
     2221 gctggtaagc cctttattgt tgttagggcg atgagcgata cagcagctca tgacgctaat
     2281 atgacctttg accagtttat tgttgaggct ggaaaaaaat cagccaaggt cttaatagcc
     2341 tttttagagg ccttacctaa tgacaactga taatcaaaaa cctgatagtt tgtggtagca
     2401 gcaaactatc aggttttttc taaatagcag ttacatagag ttgcttagca atgttttcag
     2461 ggataatcag ctccttatct gcataagcaa tggtataggt ttttgcaaag tcatctatct
     2521 gtatcagtct aaattcacta ttaactgtca gctggtgggc ttctaggtac tggataagct
     2581 caaagtgatc atgaaccctg ctcaaacgaa aaactcccag ctctttaatg gtattaagcg
     2641 ttgttttgtt gatttcgatt aggggctgct ggcgacgtgg aattgtccct ccatgagggc
     2701 aaaaggtggg atagccaagg gttttatcca agcgatcaat aaacatatct gacaccgtat
     2761 gctctagcac ctcagcctct tggtgcacct ctctagcagt atagcccagt tgatggatca
     2821 agaaaacctc catcaatcgg tgcttacgat aaagatttgc cactaagcgc tgcccttgct
     2881 ctgttagata atagccgcag gtcttatcct ttacaatcca gccttgtgag atcattttct
     2941 taatcatttc tgacacagcg ggtgcagaaa ccttcattct ctctgctacc attttgttag
     3001 aaattttaat attctgctct ccgatttcat aaatacattt caaatagtct tctttattag
     3061 gcgtcatgtc taaaagcctt tctcttattt ataatgatta ttatatcaga ttatttcata
     3121 aaaatcttga caaaggccta aaaaaaagtt atgctaatag cataattaac tatacttaat
     3181 taattaaata atagatccta aggagataac tgatgaaaaa gaaatttagc ctcgccttga
     3241 gtgctttttt ggctgttttc atgctggttg cctgctctaa tggtgggcac aaggaagcta
     3301 agagtgacaa gctcaaggtt gtggttacca attccattat tgctgacatg actaaaaata
     3361 ttgcaggtga caagattgac ttgcacagca ttgtgccgat tggtcaagat ccgcatgagt
     3421 atgagccgtt gccagaggac gttgagaaaa ctagcaatgc tgaccttatc ctctataacg
     3481 gtattaacct tgaagacggc ggacaggctt ggtttacaaa gcttgtaaaa aatgctaaga
     3541 agaaaaaaga caaggactac ttcgctgtat ctgatggcat tgatgtgatt tacctagaag
     3601 gtgaaagtga aaagggcaag gaagaccctc atgcttggtt gaatcttgaa aatggggtta
     3661 tctattcaaa aaatattgca aagcaattga ttgctaaaga ccctaaaaac aaggaaacct
     3721 atgaaaacaa cctaaaagct tatgttgaaa agctagagaa gcttgataag gaagcaaaat
     3781 caaaatttga tgcgattgct gacaacaaaa agctaatcgt cacaagtgaa ggttgcttca
     3841 aatacttctc aaaagcttac ggtgtcccat cagcctacat ctgggaaatc aacactgaag
     3901 aagaaggaac tccagatcaa atttcatcat tgattgaaaa attgaaggac gttaagccat
     3961 cagcgctttt tgttgagtca agtgttgaca gacgtccaat ggagactgtt tctaaggaca
     4021 gtggtattcc aatctatgca gaaatcttta cagactctgt agccaaaaaa ggtcaagatg
     4081 gagatagcta ctatgctatg atgaaatgga accttgataa aatttctgaa ggcttagcaa
     4141 aataatataa caataaagca cagcagcttc tggtgttgtg cttgtttgta ttaaggagaa
     4201 aaaatgattg atacgcaaaa tctttcggtt agctataacg gtaacgtaaa agctttagac
     4261 aatatctcac tacaaatcaa aggaccagct atcgttggga ttatcgggcc aaatggtgca
     4321 ggaaaatcaa ccttgatgaa ggccatgctc aatcttttag attatagtgg ccaagtgact
     4381 gttgatcaaa aggacggacg aaggctgggg catacgattg cttacgtaga gcagcgcagc
     4441 atgattgact ataactttcc aattacggtg aaggagtgtg tctcattagg tacctacact
     4501 agactagggc tttttcgtcg tgtcggaaaa aaagaatatg atcaggttga ccagctacta
     4561 gatcaggttg ggcttgctgg ctttggtaat cgtccgataa aatctctttc tggtgggcag
     4621 tttcagcgta tgctagtagc taggtgcttg attcaggagt cagactatat ttttcttgat
     4681 gagccctttg tcgggattga ttcagttagt gaaaaaatca tcattgacct gctcaaggaa
     4741 ttgaaaaaag caggcaaaac gattttaatt gttcatcatg atttaagcaa ggtagagcat
     4801 tactttgatg agttagtggt attgaacaaa gagctgatcg cttatggatc tgttgatgag
     4861 gtgttcactg ttgaaaccct atcaaaggcc tatggtgatc atctattctt aggaaaggga
     4921 atgttttaaa tgtatttgaa gttttttgag ggtctgatgt cctatcattt tttacaaaat
     4981 gcccttatta cagcagttgt tattggtatt gtttcaggag cagtaggctg ctttattatc
     5041 cttagatcca tgtcattaat gggagatgcg atttctcacg ctgttttgcc aggggtagcc
     5101 ttgtccttta ttttagggat taattttttt gtaggggcta ttgtctttgg cttgctagcc
     5161 tctgttatca ttacctacat caaggaaaac tctgttatca agggagatac agcaataggg
     5221 ataaccttta gctcctttct tgccttgggg gttattctga ttggggttgc taatagctca
     5281 acggatcttt ttcatatcct ctttggcaat attctggcag tgcaagacag tgacaaatgg
     5341 attacgatta ttgtttcggt ttttgttttg gctattattg tcctcttctt taaggaatta
     5401 ctcattacct cctttgatcc tgtgctagca aggtctatgg gaatgaaggt cactgcttat
     5461 cattatctgt tgatgatttt gttgaccttg gtttcggtga ctgctatgca aagtgttggt
     5521 accattttga ttgtggcaat gctgattacg ccagcggcta cagcttattt gtatgccaat
     5581 agcctaaagg taatgctggt tatctcctca tgcttgggag ctgtgacctc tgtgttgggg
     5641 ctctatttgg gctacacctt taatattgca gcaggctcaa gcattgtttt gacctcggct
     5701 gtggtgtttc tgattagctt ctttgtttcg cctaagcagg gctactttaa aaagcattcc
     5761 tagtaaacca tagctggctg tgctttgaaa gcaacttatg gcatgatcaa caggccagct
     5821 cttcatttag ttaacaagaa aaaaatcacg accagctctt gaatcggcgg cttttccgat
     5881 aaggagctgg tcgttttatt gttgttgtgg cttagaggct attttttaaa ggagtaatcc
     5941 ttaacaatgt cgatagcatt aatagtgatg ttctctattg gcttgtcatt tggaccgact
     6001 gggctggcag ctattttatc aacgatatcc ataccctcga taacctgacc aaaaacggta
     6061 tagccaccat ctaggctagg attgccaccc tcttcgtagg cgtcaatgat tggcttaggg
     6121 taattatcag ttgataaggc cttggcttgg ttgagcttgc tttgattgat gaagaactgg
     6181 ctgccattag tatctgcacc ggcatttgcc atagcaagag cccctcgaat gttatataaa
     6241 aatggtgaga tttcattagc aaagccttgt cccgcatctt ttttgctgtc cttgcccttc
     6301 caaatggatt ctccgccaga tccatctccc tttggatcac cggtttgaat cataaagtta
     6361 ttaatcaccc gatggaacaa aagcttgtcg taatagcctt ccttggcgtg tgttaaaaag
     6421 ttttcaacag caagcggtgc atacttgggg aagagcttga gggtgatatc gccctgatta
     6481 gttttgataa tgaccttagc ttcgtccttg ccgacttctt tatttaattg tggaaactga
     6541 tcagcgtcag ccttgagcgc ttttttgatt tttgcttcgt aagcctttgc tgctgcctcg
     6601 ctttcctctc tagctatttt ttcgtcgaca tattcatcac ctttaatagc acgatcaata
     6661 gactcacagc cacttaagct aagcaaagca agaccgatta agccaaaaga tagtagtttt
     6721 ttcatgtgta ctccttagaa caatttcttt tattttatca caaaatgact tgaaaaataa
     6781 agctaaaggg cattgagacg aagtctattt tttaactatt tctaagcttc tctaagtcct
     6841 cctgagaaac cttaaaggtg acttgcccag tctgcatatc aacgacagcc ttgacttcaa
     6901 ctcctttggg aattagtttg ccatgtccca tatcaatttg caggggaagt ttgccatagg
     6961 tcaaggtgtt aaattctttt tccatcttca actcctattt gttcttatga ttgacattat
     7021 agcataaaat caagcagctt cacctattta ttgagaattt taatgtcatc tttcataacg
     7081 attaaaaaat gttataataa ggctatggct agaagaactc aacgaaaaaa aaattcccct
     7141 aagaagcgtt taacaaaggc agagcttgaa aagcaaaagg ctattaagag aatgattgtt
     7201 tctttctcct gcgctttatt gcttgttttt gctatgctta ggctaggtgc gcttggggtt
     7261 accttatata atcttattcg ctttatggtt ggcgacttgg ctaatctctt gatattggcg
     7321 gtcctttttt acctcttttt cttcaagtgg ctcaggcaaa aagatggcct tatcgctggc
     7381 tttatcatct tgtttttagg gcttctggtt gaatggcatg cctatctttt ctcattgcct
     7441 cagctagctc atcaggctat tgttgctggg actatccagc taatcaccaa tgacctgcta
     7501 gcctttaagg ttagcgagtt tgttggtggt ggtatgcttg gggccatgct gtacaagcct
     7561 atttccttct tgttttctaa tattggctct tattttattg gttttttgtt tatcctgctg
     7621 ggcttgtttt taatgacccc ttgggatatt tatgacgtca gtcattttgt taagacgctt
     7681 tttgaaaagc tatccctggc ctatcaagaa aacaaggaaa agaggtttgt tgagcgagaa
     7741 aagcagcgat tgctggctga agaggagcgc ctatcacgcg aggccctgga ggagcaagaa
     7801 tatctggcca atcaagcgat tgatcctgag acaggtgagc ttttagcaga gccagctgat
     7861 tcgtcagcag aggctatcag ctctaaggag cctgaggcat tttttgagcc ggaaattctg
     7921 gcttatgatt cacaccctgc tgatgacgag cctgaggcat ttggagatga agaggagtct
     7981 gtaccagaag cccctctaac gggtgcttca gcaatcgcag gagaggcgcc gctgtcagat
     8041 gatgaggagc tgtcagtgga ggtcgatttc acgccaaaga ccaatctgtt gtacaagcta
     8101 ccaacgatag agctgtttgc tgctgataag cctaaaaatc aatccaagga aaagtacctt
     8161 gttcgtcaaa atatcaaggt attagaggat accttcagaa gctttggaat tgacgtcaag
     8221 gtggagcggg cagagattgg gccatctgta actaaatacg aggttaagcc ggctgttggt
     8281 gttcgtgtga atcgcatttc caatttagct gatgacttgg ccttggcctt ggcagccaag
     8341 gacgtacgga ttgaagctcc gatccctggc aaatcccttg tgggtataga ggtaccaaat
     8401 tcagaggttg caacggtttc tttccgcgag ctttgggagc aatccaacac ctctgatgat
     8461 aaattgctag aaattcctct tggcaaggct gtcaatggta gtgccagaag ctttgatttg
     8521 acccgcatgc ctcatttgct ggtggctggc tcaacaggat cagggaaatc tgttgcagtc
     8581 aacggtatta tctccagtat tttaatgaag gctagaccgg atcaggtcaa attcctaatg
     8641 gtcgatccga aaatggttga gctgtctgtt tataatgaca ttcctcacct gttaatcccg
     8701 gtggtcacca accctcgtaa agcaagcaaa gcgcttcaga aggttgttga tgagatggaa
     8761 aatcgctatg agctgttcag taaggtcggt gtccgaaata ttgcaggcta caatgccaag
     8821 gttgaagcct acaacaagca atctgagcaa aagcaaatcc ctttgccgat gattgttgtt
     8881 attgttgatg agctagctga tttgatgatg gtggctagta aggaggttga ggacgctatt
     8941 attcgtcttg ggcaaaaggc gcgtgcagca ggtatccata tgattttagc tactcagaga
     9001 ccttctgttg atgttatttc tggattgatt aaggccaatg ttccatcacg cattgccttt
     9061 gcggtttcat caggaacaga tagtcgcacc attcttgatg aaaatggcgc tgaaaagctg
     9121 ctcggtcgcg gggacatgct ctttaagcca attgatgaga atcaccctgt gcgtctgcaa
     9181 ggctccttta tttcagatga tgatgttgaa cgcattgtta gctttatcaa ggagcaggca
     9241 gaggctgatt atgatgatta ttttgatcca ggtgaggtta gtgactctga tcatggcagc
     9301 agcggagctc ctgagggaga tccccttttt gaggaagcaa aggctcttgt gttggaaacg
     9361 caaaaggcaa gcgcctcaat gctccaaagg cgtctatcgg ttggctttaa ccgagcaact
     9421 cgactgatgg acgaattaga agaggccggt gtcattggtc cagctgaagg gactaagcca
     9481 agaaaggtac tgcaaaccaa ttaagaaaga gcttatttaa aggctcacaa taaaacaaac
     9541 ccgtaccaag ctaagcttaa cctgtggctt gatacgggtt tttgatatgc tgctttgaaa
     9601 aaagtcccac tcaagcagaa agttcaaaga cagcttcctt ttgagtgata gtgctagagt
     9661 taattggcag attcagactg ctaggcttga agtcatgtct ggtaaggcac taaacgataa
     9721 aaataagacc aactagcatc aggtaaaaga gtagtgtgac taaaaagcct actcgccaaa
     9781 atagtttgaa aaatcggcgg taagaaaact gctggattct gatgatcagt aagagtgcca
     9841 taacaatggc caatagggac ataacaatca ggtaataagg cagcaaatga tgggtgaaaa
     9901 attttcctga tacaataaca atttcaaaaa caaaaagtgg taaggctaaa tcagggaatt
     9961 taaggcctct tcgtcccagt ctcaataaag atatcattat catagagaat aagggagtca
    10021 ggataataaa ggctaaggct gttaatttgt agatgatcat aagtctattt tatacccaat
    10081 tgatagactt gtaaactaat tcctgctttt agtggctaaa agagctggta catcggctaa
    10141 tacctgaaaa agctgacctc ttgaccgaca aaaagagctt agcagcaagc ttgttgaagc
    10201 ataggactaa gctcttatca cggttaaacc aaaatattat gattgttgat tgcttctctt
    10261 ttggaagccc actcaatagc ctgaaaaagc ttcagaagct tagcctctga gatacttggc
    10321 aggtatagct tgttcttgtg cttgttaaga atatgattga cagtatcatc aataactaga
    10381 atattcccct tagacacacc ttcgatgtcg caaatagagt gaatccagca aatgttatca
    10441 aactgttgag cgagaccctg agtgatttct tggttttgaa tcggcaagct aaccagctca
    10501 aagggctccc ctgcaaaata agcactagct ttattgaaca ggagatgagg gtcactatta
    10561 atctggaaaa ataagggatc atcaataata ctatcaatag caatcaaagg aacaaaattg
    10621 ctatttccga tcttgtaaaa ttcctctttg gtgacctcta gggtgagaat gacatctgct
    10681 acatcatatt ttccgatgta ttcttgatta aggcaaatca aatgatagtg ctttgtgtaa
    10741 agaaaggcag atagctgggt aataaagtga agctgctctg ctctttttaa aacagagctg
    10801 tgctctttgt agtaaagggc gattagctgt cttttttgtg tcacgagtga ttttgcggct
    10861 tggtttggcc gataatttaa aagattaatc atttgcagca ctttattgcg cgtttcaggg
    10921 ctaatttttt gatcttctct gttattgatg acataggaga cagtagccac agaaactccc
    10981 gcctcgcgcg cgacatcttt gatcgtaact ttcttatgca tagctttgtt ataataaaaa
    11041 aacgcttaaa agtcaactag aagcggctcc ttggaagcct cacaagcttg tactgctagc
    11101 gccataggag acatctgcta tttgcggcaa cattttttgt gaaaatgact tgatttatct
    11161 gtctaataag gtataattgt aaggtatgct ctagcatacc tgtgggaggt aaaaatcgtg
    11221 aattaccgcc aaaaccacaa caggaggatt tttaaaaatg gctaaaaaag tcgaaaaact
    11281 tgtaaaactt caaatccctg ctggtaaagc gacaccagct ccaccagttg gaccagctct
    11341 tggtcaagca ggtatcaaca tcatgggatt cactaaggaa tttaatgctc gtacagctga
    11401 tcaggctggt atgattatcc cggttgttat ctcagtttac gaagacaaat catttgattt
    11461 catcacaaag acaccaccag ctgctgttct tttaaagaag gctgcaggtg ttgaaaaagg
    11521 atcaggtaca cctaacaaaa ctaaagttgc gacagttact cgtgcacaag tacaagaaat
    11581 tgctgaaact aagatgccag atttaaacgc tgcaaacatt gaagctgcaa tgcgtatgat
    11641 tgaaggtact gctcgttcta tgggattcac cgttactgat taatcagcaa cctgccctta
    11701 ttacccgcaa gacttcatca tagagatgag tgacgtggga gatttttaaa tcaaatcgat
    11761 atgaccacat tacaaggaga agataaaaat ggctaaaaaa agcaaacaaa tgcgtgcagc
    11821 acttgaaaaa gtggacagca caaaggcata cagtgtagag gaagctgtag cactcgcaaa
    11881 agaaactaac ttcgcaaaat ttgacgcttc tgtagaagtt gcttataact taaacatcga
    11941 cgttcgtaag gcagaccaac aaattcgtgg tgcgatggtg ttgccaaacg gaactggtaa
    12001 aactcagcgt gtccttgttt ttgctcgtgg agcaaaagct gaagaagcaa aggcagctgg
    12061 tgcagacttc gttggtgaag atgaccttgt tgctaagatc aatggcggct ggcttgattt
    12121 tgatgttgtt attgcaacac cagatatgat ggctattgtt ggacgtcttg gacgtgtcct
    12181 tggacctcgt aacttgatgc caaaccctaa aactggtaca gtaacaatgg acgttgctaa
    12241 ggcggttgaa gagtctaagg gtggtaaaat tacctatcgt gctgataaag caggtaacgt
    12301 acaagctatc attggtaagg tatcatttga tgctgacaag ttggttgaaa actttaaggc
    12361 tttccatgag gtaatggtta aggctaagcc agctactgca aaaggtactt acatgactaa
    12421 cgtatctatc acaacgacac aaggtgtggg tatcaaggta gatccaagtt cattttaata
    12481 agtaattaag gactgaccct aaaagggatt ggttttgaga cagatatcat gaattggtgt
    12541 ctgtcttttt ttgattaaca ttgtgaggat agcctttttt agacgaagcg tcacgattga
    12601 tatatgatga taagatgaag cagattgctt gatctcaata tctattagtc aaaataccac
    12661 tttacagctc atggtaacaa tgagaccttt ggaaggactg tggcacagaa agcctctaaa
    12721 tccctcgtgt cgttactacc catcaatctg caaaaaagcc tatcgttagg agtaaaacga
    12781 taagcttttt gtcctctagt tgatagccaa tgattaaagg gctatgggta atgctttaat
    12841 tattgttttc ttttgcgtct agttaagaag cctaatccga gaagagagag taaacctgtt
    12901 cccaatactg tgctcaagct gcctgtgtca tttgtttttg gcagtgattt gccgttagat
    12961 tggctagtag cgtttgacgg cttggttggt ttttgaggtt tagcttctga ctgaggcgca
    13021 ggtttagatt gaggtttagc ttctgactga ggcgcaggtt tagattgagg ttttgtctct
    13081 ggttgaggtg taggcttagg ttctggcttg gattccggtt taggatccat tggcttaggt
    13141 gcagggtcag gcattggttg tggcattgga tctggggtag gagtaggatt ttctccacga
    13201 gg
//
LOCUS       DARYSY010000054        13006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYSY010000054 DARYSY010000000
VERSION     DARYSY010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13006
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(678..764)
                     /locus_tag="TVR04_001578"
     tRNA            complement(678..764)
                     /locus_tag="TVR04_001578"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(728..730),aa:Ser,seq:gga)
     gene            complement(824..1459)
                     /gene="trmB"
                     /locus_tag="TVR04_001579"
     CDS             complement(824..1459)
                     /gene="trmB"
                     /locus_tag="TVR04_001579"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1270255.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEIDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYPDNVMTEYEARFAKKGQVIYRLEATF"
     gene            complement(1459..2250)
                     /locus_tag="TVR04_001580"
     CDS             complement(1459..2250)
                     /locus_tag="TVR04_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1270256.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(2313..3347)
                     /locus_tag="TVR04_001581"
     CDS             complement(2313..3347)
                     /locus_tag="TVR04_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270257.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLFLRLLLLSSLALAFISNSYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(3351..4076)
                     /locus_tag="TVR04_001582"
     CDS             complement(3351..4076)
                     /locus_tag="TVR04_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270258.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4612..5043
                     /locus_tag="TVR04_001583"
     CDS             4612..5043
                     /locus_tag="TVR04_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270259.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTISEKPQEVVI
                     TDGWQTISEKPQEVSTTNEAGEAQEAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVP
                     DKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5495..5914
                     /locus_tag="TVR04_001584"
     CDS             5495..5914
                     /locus_tag="TVR04_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1270260.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQRATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYNQEDGIAIQYTTHEPDFPALAALAQQISQEVSQ"
     gene            5911..6213
                     /locus_tag="TVR04_001585"
     CDS             5911..6213
                     /locus_tag="TVR04_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1270261.1"
                     /translation="MTLKTMATIGLTSVLAYQVYRKRHQIKETLVAMKTSKKAIQADV
                     DRIKANLAVIQKEAQTLQAAGTELTYKWQAFSQEAQAHLTEIQKHMSKYQQERPEA"
     gene            complement(6378..7640)
                     /locus_tag="TVR04_001586"
     CDS             complement(6378..7640)
                     /locus_tag="TVR04_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1270262.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSNGATTGTPAAP"
     gene            complement(7641..8168)
                     /locus_tag="TVR04_001587"
     CDS             complement(7641..8168)
                     /locus_tag="TVR04_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1270263.1"
                     /translation="MSEQVVTIEEAKASEASALITLIKEAADETDFIIGTEDIIAATV
                     EELECFLEASQESLTDICLLLKVGDTLAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETALDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(8161..8604)
                     /gene="tsaE"
                     /locus_tag="TVR04_001588"
     CDS             complement(8161..8604)
                     /gene="tsaE"
                     /locus_tag="TVR04_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1270264.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGI
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGSGVTVIEW
                     GELLAKGTLHDYLEILITKTAAGRQVDYLAHGCRSEALLEELKHV"
     gene            complement(8973..10433)
                     /locus_tag="TVR04_001589"
     CDS             complement(8973..10433)
                     /locus_tag="TVR04_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1270265.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDIDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10691..11503
                     /locus_tag="TVR04_001590"
     CDS             10691..11503
                     /locus_tag="TVR04_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1270266.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQAKGHEVIISTG
                     RPYRMALDYYLQLELKTPMISFNGSLTHLPEKRWKYEHNVTLDKAYLLKLLAVQEDFQ
                     MDFIASEYRKAFYITMNRPESIDPNLFGVKAITPDMALQIDKITQDPNALLMQTHHED
                     KYALAKAMQSFFKDEIEVDSWGGPLNILEMSPKNINKAYALKYLLSIYNKDKQDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPFADQQLAYSNEEDGVARKLEELFL"
     gene            11855..12847
                     /gene="manX"
                     /locus_tag="TVR04_001591"
     CDS             11855..12847
                     /gene="manX"
                     /locus_tag="TVR04_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1270267.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEKASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDDLRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSMAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
BASE COUNT         4059 a         2871 c         2492 g         3584 t
ORIGIN      
        1 aacagactcg tatttcaagt gacatttgat atacttgaag atgagaatac tgcttgagtg
       61 gaggcattgt aggtctagtt caacgtaaag cagcagcgga aatagcgaaa ctaatactta
      121 aagtgggcat caagaacgta gcccctgctg cagctgcaac atcattaatt tggagctttg
      181 gaaggtgcat gtggttttaa tgtcaaaaag atatagtatt tgtataacat ttcttgttat
      241 tatttcgaga ttcatttggt ttgcccttac aggaagaggt cctttttatg actttactgg
      301 gactatattt ttaggagtag tggttttact aattagtcaa aaagtattga aaaaattaga
      361 gtaacaaaat tattaatccg acaacagcga agcggaatgt gatattatcg atatgttcca
      421 taagatactt tctaatgaga ttgttagtgc ttctcatgat aagtcttatg ggactttttt
      481 gtactcaaaa agctctatca tttccatact ggataaatcc actacagaaa tgatagagcc
      541 taaaatatat gttcaccaat tggataagtt aaaagaaaaa aatgaccatc aggtcaaaag
      601 catttttcaa aatctcaaat ttgacgggtg aaaaacgggc gaaaaccccg aaacccttga
      661 tataccaaga ggatataagg agaggagggg attcgaaccc ccgagccccg ttaaggacta
      721 cacgctttcc aagcgtgcgc actcggccac tatgcgacct ctccagataa aaggctgatc
      781 aactcaacct caatagtgta tcatattttt gtcaaaatag ccactagaat gttgcttcta
      841 agcggtaaat aacctgcccc tttttagcaa atctagcttc atattcggtc atgacattgt
      901 ctgggtaatc actagcatgt aagtccagcc aaacctgctt gagtgtcatg ccatactgtg
      961 aaaagctcgc taggctatac tcaaataagc cacgattatc tgttttaaaa tgaatctcac
     1021 cattttctgg caaaatctgc ttataggtgt ctaaaaagga cttgtaggtt aatcggcgct
     1081 tctcgtgcct gctttttggc caaggatctg aaaaattcaa atacatcatg tcaatctcac
     1141 cagcatcgaa ataattggtc aggcttgacc catcaacccg caagagccta acattaggag
     1201 cctgagaagc taggacctta tctaaagcat agcttagcac tgatagctga atgtcaatac
     1261 caatatagtt gatctctggg tttttcaacg ccatacctgt gataaaagct cccttgcctg
     1321 agccaacctc aatatggatc ggatgatcat taccaaagac ctcacaccag cgccccttag
     1381 cagcctccgg ctctaaaatg acatagtgag gattgttttc caagtgctcc tgcgcaccct
     1441 ttcgttttct aactcgcatt atttctttct aaacatttct ctaaatttcc taagagcgta
     1501 aatctcttga ttgacatgct ccatatctct cttatcaaag caccttaaaa tctgagttag
     1561 ataagagaat tgagcatacc aaataatctt ttgcatgacc ttatcattat ttttatagcc
     1621 ataataggat agccagtctg cccaacggga gcgtggaata tagtggctta gcaaataagc
     1681 cacatcatac attcgatctg ttaggcgcac acaatcccag tccaccaaaa aaatcatgcc
     1741 actggtggta atcacccagt tgctatgctt gatatcacca tgtacaatcg tggccacctc
     1801 agagcgaaat tcaggtagac tgcgctttag ctccttgaca atagcctgta aataagaatt
     1861 ctgttgaatt tgcaaaggtg cattttgctc aaagtcgact aaaaggtcat aaggattttc
     1921 aattttatag ttgagctgaa gcaattgatt aaccaactgc ttggacttgt ggaggcgcag
     1981 caggatatgg acgatttgct tactgttcat atcttctcta gtcagggtac gaccattgag
     2041 ccactcttga gcactcatca tatcgccatt ccccatacgc tttgcccaaa gcaattgtgg
     2101 ggcaatctgt tcctttgcta aggcaggtag gattggtgtt gtattaagct tgataaagac
     2161 gctttcgcca tttggatagg tccctttgta ggctttgcca ctttttccgc gcaagggagt
     2221 caatacaaga tcctgttcag ttgttgtcac cttatcccct ccttttctat cttctgtaac
     2281 cagttatccc tattttactt gttttaaagg acttagtcaa tcatcttctt taacttgtac
     2341 ggtaagtaaa gaagatttaa taatcccatc gccacaatca acacaagagc attttgccaa
     2401 gaacggcaga gcacaagatt gacgataagc atcaaaccac ttaattgcct caacaaagaa
     2461 agtagatttc tttgcttatg ctgtggttta gtcgggtaaa gcccactcat ataatggtaa
     2521 tcataatgat gataaagtga taataactga aaaagactta aataatgaaa gaccaaggcc
     2581 aagcctactg ctaaataaga gttggaaata aaggcaagag ctaaagagct aagcaagagc
     2641 agacgtaaaa ataggcctaa ataatcagag ctgcgtaaaa atgcccttag atataggttt
     2701 gtccaaacct ttttgctatc tgccttgata agcttaagta taggattcaa gtaaggcctt
     2761 tccttaacct tggttgagat tcctttaaca tttgtaaaca aagcataaaa ctttaaaatg
     2821 gcctgctggc gatctgcctc aaaagcaatc gctttttccc aatcaagccc cttggagctc
     2881 aaaaagcttg ccaccttacg ctttaacagt aagcgcttag ccagcaccaa aacaccaagc
     2941 aatagcacaa aggcaagcaa ggaaacacca agcctttgaa acaaaggaaa taaaggtaac
     3001 agcaagaccg tttgaaggct agaccaaaga ataaaggaca agcgctctgc tgacctgata
     3061 tgggcaataa cctctgcctc cttggtcagc aaaaaatgct gatcagcctt ttcaagatag
     3121 gtagcaactg accccagatt aagcaaaaac aagacagcaa tcaacaagcc tagctgaatc
     3181 ggtagaggat tagcaggaaa atgcttgagt agttgactgt actgaaaaag aataaagccc
     3241 aaaagaaaca gcaagacaag aacaaaatga tcattaaaga cataaggcag atacttggta
     3301 tgcttgtgct gaaactcctg acgacgctta cgaaataatg ccttcatagc ttacccctct
     3361 tttgtcagcg ctaggtaaat gtcattaaga ctagctgaag catctccaaa gactgcctgc
     3421 aaatccgcca gagtcccttg tgcacgcacc tgtccctgat gcaatatcac aaaacggtca
     3481 cacatttttt ctgccgaatc cagcacatgg gtactcatta gaattgactt gccctttgcc
     3541 ttttcaacct ctaaagcctt aatcaaatca gcaattgcta aggggtcaag ccccaaaaag
     3601 ggctcatcaa gaataaaaag actagggtca atgacaaaag cgcaaataat cataaccttt
     3661 tgcttcattc ccttagaaaa atgcaccgga aaccaatcca gcttatccgt caaacgaaac
     3721 agctctaaga agggctcagc tcgcttatgt gccagctcca catcaatatc ataggccata
     3781 gctaccgtat tgatatgctc tgctaaggtc agctcctcat ataagcttgg tgtttctggg
     3841 ataaagccaa ttttcttgcg ataatcagct tcatgctccg ccaaggttaa gccatcaatg
     3901 gaaatccttc ctttatatgg ctttaaaaac ccaataattt cattaatcgt tgttgactta
     3961 ccagcaccat ttagaccaat aagccctact agctctccat ttccgacaga aaagctaata
     4021 tccttcaaaa ctggaatatt aaggtagcct ccagtgacat tctcaatgtt taacatatca
     4081 tttctttcta atatctaatc tattgtagct ttgcatacta gcttccctag atgacaggtt
     4141 attagcctag acagatagga cttactaggc aatgctttgt catcatcagc ctatccagcg
     4201 ctttgaagca ctgataagac cgattagctt gaccctactt aagaaagctg gggcagctaa
     4261 tactaagggt acacttatat tagctattat aacaaatttc tgcacagagc gttaactgtt
     4321 ttgatcaatg ctcccatcag ctaaaaacgc tgagtgaatc tgaagtctat tttaagatca
     4381 tcaagaaaaa ggcctagcta taaaaacaga ggctatatta gcttgatcta tcagtcctaa
     4441 ccatctatca catcatattc taatgaccta gtgagcctag atagcagctc atctaagggt
     4501 tcatctaaaa atcatgataa tattatctta ttgtattgaa tttttaataa tataatgtta
     4561 tcgttaactt gtaaataagt gttgcgtctt taatgacaaa ggaggtatgt tatgaatttg
     4621 tcacgctttt taacatttgg cttagtatca ctttcagcac tttctatttc aggcctagtc
     4681 caaacagagg ctaaggctaa cgaatggcaa actatctctg aaaagccaca ggaagtggtc
     4741 atcacagatg gctggcaaac tatctctgaa aaaccacaag aagtaagcac tacaaacgaa
     4801 gctggagaag ctcaagaggc tgttcctgat aaattctcac aaaacgaaga ccctagctta
     4861 tgggctgttc ctgataaatt ctcacaaaac gaggacccta gcttatgggc tgttcctgat
     4921 aaattctcac aaaacgagga ccctagctta tgggctgttc ctgataaatt ctcacaaaat
     4981 gaggacccta gcttatgggc tgttcctgat aaattctcgc aaaacgaaga tcctagcctg
     5041 tagtaaagcc atcaaaactc gattgaagat aaggcctatg ttgctgacgc ttcaatcttt
     5101 ttttgttcta aaaactttct cagccttaac cgtcaagaag ctccagcacc tcatactctc
     5161 tgaagctctt gtccttacag atattgtgcc atgtcactat catacgataa tgcgcaaatg
     5221 cacacctttt aaggatctag cttacagcaa atagcaagcc tagctgtgtg cttaaccata
     5281 atcgcttgtc catcagcatg attcaaaagg ccttgctagt catgtgatca ataaccatta
     5341 gctccagcta caaacaattg caatatagac cagtacatgc taagataact atagtatgag
     5401 atagctatgg tcactgagca actactgatt tcttattcta aaattattca actactgatt
     5461 tgagccattg ctacgcagac gaaaggatta tcacatggaa aattgtatct tttgcagcat
     5521 tattagcggt gagattccct cctccaaggt ttatgaggat gagcaggtac tcgctttttt
     5581 ggatatttcg caaacaacag cgggtcatac cctcttgatt cctaaaaagc atgtccgaaa
     5641 tattctggca atggacgccg agacagctag ccagaccttt gaacgattac ctaaaatcgc
     5701 tcgcgctatt caaagagcaa ctggtgctac tgcaatgaac attatcaaca ataatgaaga
     5761 gttagctggt cagactgttt ttcacgcgca tgtgcacctc gttccgcgct acaatcaaga
     5821 agacgggatt gccattcagt atacaacaca tgagcctgat ttcccagctc tagcagcctt
     5881 agcacagcaa attagccagg aggttagcca atgaccctaa aaacaatggc cacaattggt
     5941 ctcacatctg ttttagccta ccaagtgtac cgtaaacgtc accaaatcaa agaaaccttg
     6001 gtagccatga aaacctctaa gaaggctatc caggccgatg ttgataggat taaggcaaat
     6061 cttgctgtca ttcaaaagga ggctcagaca cttcaagcag cgggaacaga actaacctac
     6121 aagtggcagg catttagcca agaagctcag gcccatctga ctgaaatcca aaaacatatg
     6181 agcaagtacc aacaggaaag accagaagcc taagcagccc accaagcctc aaggcaacaa
     6241 aaaagggctc tatcatttct gtagtggcca agtctgctat aggaaggata ggactctctt
     6301 ttatatgtac aaaaaaacga agaaatcact cacaggatca agccttgata agatttcttc
     6361 gtttttttgg ctgtacccta aggcgccgct ggtgtaccag tggttgcacc atttgattgc
     6421 tgctctgctg gtgagtctgc ttgagggcta ggagtcacat tagctgctcc tgactcttgt
     6481 gtaccagctg ttgtgtcctg atagctgctg ctagaggacg tctctgagga ataggttgag
     6541 tactgggtag atgagtctgt ataggctggc aggctgcctg aattgtagta ataactgcta
     6601 tcctgagtag actgagtctt taatgagcca taaaggtttt cgtaaactgt ggcagtcgtt
     6661 tttagctgac taagcttttc aaggcctaat tcagcacgaa tgcgattttg gatttctaaa
     6721 agatgatctg aggtcacaat ttgataggag ccgccatctg acaaggtcgc tccctcaccc
     6781 tttagctgat aggtcttgat atttttaagg gcgtctgtat agcctaaaag attaggaatg
     6841 gttcgtgatg atatttcaat gttggtttgc atattaccac taacagctga caagatcttt
     6901 cggtaggagc tgatactatt aagggcaaga atctttttca gcaccttttg aataacctct
     6961 cgctgacgct tctgacgacc atagtctccc tctggatcat catagcgcat tcgagcatag
     7021 accaaggcct gctctccatt tatcttgtga gttcctggtg caacggtagc ctgatactca
     7081 ggctcattgt ctgcaataga gataggaaag tcaaattcat tggtaacagt aatgccacca
     7141 acagcattaa ccaaatcaat gagcccttgc atgttaatct gaacgtattt gtcaatcgtg
     7201 atattcagca agtcctgaac ggtcatgata gccatttggg caccaccagc tgcataagca
     7261 gcattcaact tagcttctgc tccattcatc tcattatcat ttggacctga cagagtgatg
     7321 agaatgtctc tttctaagct tgtcatggtt gtctttttgg tcttagggtt aatcgtaacc
     7381 agaatcatag aatcactatt tccttgccag gtagaggttc tgtgagacga tcctgtgtca
     7441 actcccatca atagaattga aaagggctct gtctgttgaa tggcatcact ttttttggag
     7501 gacgttgcaa aatccttaaa ggtctttgac aattctccag ttgaaaaggt ataggcattg
     7561 gttaggtaaa ctcccatagc ccccaaggtc aacagcacaa tagctgtcag cattaaaaag
     7621 attttttttc caattttcat ctattcacgt tccagatatt tacgcataag gtaaacatcc
     7681 tgatagtctc catttcttga tttgacgtcc tttcttttga cgccctctat tttaaagcca
     7741 tatttttcat aaatatgata ggcacaggta tttcgagcct gaacctccag ctccaaagca
     7801 caaagctgct ttgtttctct ggcccaatca agggcagtct ccatcaaaag ctgtcctagg
     7861 ccatgattgc ggtagggttt caagaccagc ataaagcaat cgccaacata gctagtctca
     7921 cgatatgctt tgccagctat atttagcaga ccagctaatg tatctcccac ctttagcaaa
     7981 aggcaaatat ctgtcaaaga ctcctgacta gcctctagaa aacactcaag ctcctctacg
     8041 gtagcagcta tgatatcctc agtccctatg ataaaatctg tctcatcagc agcttccttg
     8101 atcaaggtga tcaaagctga cgcctctgag gccttggctt cttcgattgt aaccacctgc
     8161 tcagacatgc ttaagctcct caagaagcgc ctctgatcga cagccatgtg ctagataatc
     8221 aacctgcctg cctgctgctg tctttgttat taaaatttca agatagtcat gcagggttcc
     8281 cttggctaaa agctcgcccc attcaatcac agtaacccca ctaccaaaga taaaatcatc
     8341 taaatcaata gagtctggat catcaccaat ccgataaaca tctaaatgat acaagggtag
     8401 tcttccctca tattctcgag cgatagtata ggttgggctt ttaatcatct gatcaatccc
     8461 caaaccctta gcaatcccct tggtcagcgt tgttttacca gcacctaagt caccagtcaa
     8521 gacaagcaca tctcctgcct ttagctgcct accaatgcct tgtccgtaag cgattaattc
     8581 attctcattt ttgctataaa acataaggct attataacag aaaaaaaacg gtcttccaag
     8641 cctaagccag cctgtcagta aaatattcta ggctcgtaat tcctcatata gtgtcgtcaa
     8701 agctcaatca gctttaaagt ccaataaatc aaaagggcta tcagcaaatc aagcgagtct
     8761 aacagtcatg atattctgct gtgatagcca gggctgaatg ctctagaaat caacccgcag
     8821 ctctaaaacc tagcctaaaa tctttagcta tcgtactacg aaaaaggcta caatgcgtat
     8881 aagcttagaa agtccatagt cccagtccaa acggtgatcc ctgtctttat tgtcccagca
     8941 aaaaagaggc acctaagcac ctcattagtc gtttacaata acgctaaaat gataaaattc
     9001 aaaacaaata agaaggttgc tccccaaaga atcgggtgaa tctccttggt tttgcccttc
     9061 acaagcttca ccaagcaata gaaaataaag gagccagcca caccgtatga aatagagtag
     9121 caaagtgcca taaagaaagc ggcaaagaag gacggtaggg caacatcaaa gtcgctccaa
     9181 tcaatatcaa ggaaggacga taccatcata acaccgacaa tgattaaggc tggtgctgtc
     9241 gcagcggctg gaacaatgcc aacaatcggt aataataaaa cagataagac aaagcagaca
     9301 gcagttgata cagctgttag acctgtacgt cctccctctg caataccagc agcagactca
     9361 acgtaggttg tggtatttga ggtgccaaat agagctccga ttgaagtacc aatagcgtca
     9421 gcaaagagcg cacggtccat ttttgagcta aagccagagc tgttttccaa agctctctca
     9481 tcctcctcag agaaaatccc tgttcgacga ccagtcccaa caaaggttcc aatcgtatca
     9541 aaggtatcag atagactaaa ggcaaagatc gtcattaaaa caagcggcaa gcgacttgaa
     9601 tcactaaaca gtgacgccat gccaccaaag gcagccaaga atgttgtccc taattcagca
     9661 aaggctgagc tgatgtgatt gtctgcaaaa ttaacagcag aaagatcaac cactccaata
     9721 ggaataccgg ctaaagttgt aactgtaata ccaattagga tggctccacg aacgttctta
     9781 agcacaagca ctgctgttag cagcagacca aaaactgcta gcaaaacact cggatcggtg
     9841 aaggttgaaa tagctggaac cacaccacca ttagcattaa cggaaaaaac gccattagca
     9901 aatgtttcag cagttgcctt agctggctca acaccattta cagtaacaat ctcagcagat
     9961 gatagcgaaa aggtgatcag gttagcattt ttaaaaccta gataagcaac aaagactcca
    10021 atacctccgc caatagcatg ctgcaggctt actggaatag ccttgataat gctcttgcga
    10081 agctttgtga cagtgataaa gatattaaac agaccacaaa gaaagacaat agccaaggcc
    10141 tcctgccaag aaaatcctaa gctaaaaaca acagtgtaag taaagaaagc attaagtccc
    10201 ataccaggag ccaatgcgta aggcacgtta gcaaacaaac ccatgatcaa ggtagagata
    10261 gcagctgcaa tgatagtcgc taaaaacacc gcctgtgacg gcatacccgc tgcactcaaa
    10321 atacttgggt taacaaataa gatatatgac atcgcaaaaa aggtcgtcac accagccatc
    10381 agctctgttg aaaccgtcgt gccattttct tttaacttaa aaaacttttc catttgaatg
    10441 gagtctcctt attgataggc aaaatcaaaa aagcccttat ctcatcagat aagctttttc
    10501 tcttaaaacc aaatgattat tatcgttttt acgaacgata tattcatcat aacattttat
    10561 cgttctattt tcaacagctt tttttcgttt gtttatcatg atcgttcaaa atttaacagc
    10621 ctttttctat caaccgccca agcagcaatt ttctcttcca ctgaccctaa aatctgttat
    10681 aatctagtgt atgactaaaa aactaattgc tattgattta gacggtactt tactacatca
    10741 cgacaatacc atctccacct atactcaaaa aaccattaaa gccgtccagg ctaagggaca
    10801 tgaggtcatc atctcaacag gacggcctta tcgtatggct cttgactatt accttcagct
    10861 agagctcaaa acacccatga ttagctttaa cggctctttg acccacctcc ccgaaaaaag
    10921 atggaaatac gagcataatg tgaccttaga taaggcctac cttctcaaac tcctagcagt
    10981 gcaagaggac ttccagatgg actttattgc tagtgagtac cgaaaagcct tctacattac
    11041 catgaatagg cctgagagca ttgatcccaa cctttttggt gtcaaagcca tcacaccaga
    11101 catggcttta cagatcgaca aaatcactca ggatccaaac gctctcttaa tgcaaacgca
    11161 tcatgaggat aagtatgccc tagccaaggc catgcagtct ttcttcaaag atgaaattga
    11221 ggttgactcc tggggtggcc ccttaaatat ccttgagatg tcccctaaaa acattaacaa
    11281 ggcctatgcc ttaaaatacc tgcttagcat ttacaacaag gataagcagg atctcatcgc
    11341 ctttggtgat gagcataacg acacagaaat gctggccttt gccggaaccg gctatgccat
    11401 gaaaaatgcc agccctgtgc tgctgccctt tgcagaccag caattagcct actccaacga
    11461 agaagacgga gtcgctagaa aactagagga gcttttcttg tgaaagcaaa cgaaaccatt
    11521 gttttgcaga aaacgatggt tttcttaatg ccgtttccgt caattgatga aagaatttct
    11581 aatattttcg ttatttttca gcatattttc ttttttatgc ggcataaaaa tccctttatt
    11641 atcaatattc tacttattcg gcagcgcatt atgaaaattt tttcatattt cgtaagattt
    11701 ttccgaaagg gcttgatttt taagtgaaaa cgttttaaaa tagagacgtt cttgaatttc
    11761 gtttaagtga aaaagaattg ccaaatgcta tttggaagga gattattctt cttcatttca
    11821 acgaaaaata ttttaataag gaggaagaac aagaatgggt atcggtatta ttattgccag
    11881 ccatggtaaa tttgctgaag gtattcatca atctggttct atgatttttg gtgaacaaga
    11941 gaaagttcaa gttgtgactt tcatgccaaa tgaaggacca gatgacctgt atggacactt
    12001 caacaatgct atcgcacaat ttgatgctga tgatgaaatc cttgtactag ctgacctttg
    12061 gagtggttct ccatttaatc aggctagtcg tgtggcagga gaaaatcctg atcgcaaaat
    12121 ggctatcatc actggtctca atttgccaat gcttattcaa gcctatactg agcgtttgat
    12181 ggacgctaat gcaggtgttg aacaagtagc cgcaaacatc attaaagaat ctaaggacgg
    12241 tattaaagcc cttcctgaag agctcaatcc agttgagaaa gcttctacag ctaatggtgg
    12301 tggtcaagcg cttcaaggag ctattcctaa aggaactgtc attggagatg gtaagctaaa
    12361 aatcaacctt gctcgtattg acactcgtct tcttcatggt caggtagcaa ctgcatggac
    12421 accagcttct aaggctgatc gtattattgt agcgtcagat tctgtggcta aagacgatct
    12481 tcgtaagcaa ttgatcaagc aggcggctcc tggtggggtt aaggctaatg ttgttccgat
    12541 caataaattg attgaggctt ctaaggatcc acgctttggc aacactcacg ctcttatcct
    12601 gtttgaaact gttcaggacg cccttcgtgc gattgaaggc ggcgttgaga tcaaagagct
    12661 gaacgttgga tcaatggcgc attcaacagg taaaacaatg gttaacaacg tattgtctat
    12721 ggacaaggat gacgttgctg cctttgaaaa attacgtgat ctaggtgttt catttgacgt
    12781 tcgtaaggtg ccaaatgatt ctaagaaaaa cctatttgag cttatccaaa aagcaaatgt
    12841 gcaataagca atttagaaat aagaggtagg cttgtttaac gcaacaagct gtctgcctca
    12901 tctacaatgc tgcgatgata tgataagcct gatgattgtt tttagacaaa tcatcatcac
    12961 ttaataacgc tttatattgt ccattgacaa ttgactcata tacgaa
//
LOCUS       DARYSY010000055        11538 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYSY010000055 DARYSY010000000
VERSION     DARYSY010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11538
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(235..1680)
                     /locus_tag="TVR04_001592"
     CDS             complement(235..1680)
                     /locus_tag="TVR04_001592"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1270268.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSADEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPIFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDESRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(2288..3001)
                     /locus_tag="TVR04_001593"
     CDS             complement(2288..3001)
                     /locus_tag="TVR04_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1270269.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGLMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(3129..3635)
                     /locus_tag="TVR04_001594"
     CDS             complement(3129..3635)
                     /locus_tag="TVR04_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1270270.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            4019..4297
                     /locus_tag="TVR04_001595"
     CDS             4019..4297
                     /locus_tag="TVR04_001595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270271.1"
                     /translation="MKRIKTICLLAAAAVLTLAPISTGQTQSQTIYASQVLEDQCINL
                     GNGVIRCPNKDGVGQDFYDPDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(4458..5819)
                     /gene="radA"
                     /locus_tag="TVR04_001596"
     CDS             complement(4458..5819)
                     /gene="radA"
                     /locus_tag="TVR04_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1270272.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHVNGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDIPSGIEVVGVMTVGEVLKA
                     VFA"
     gene            complement(5886..6332)
                     /locus_tag="TVR04_001597"
     CDS             complement(5886..6332)
                     /locus_tag="TVR04_001597"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1270273.1"
                     /translation="MTRIRGFELVSGFTDTELLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTVTLAVGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(6512..7279)
                     /locus_tag="TVR04_001598"
     CDS             complement(6512..7279)
                     /locus_tag="TVR04_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1270274.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKAWAREDVRPKILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFIKTVRGLEKEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKI
                     QGVDLVQVKKDAKAFLVDKDLEADFPRIRFSYAGKEI"
     gene            complement(7441..9237)
                     /locus_tag="TVR04_001599"
     CDS             complement(7441..9237)
                     /locus_tag="TVR04_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270275.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLTYLFIAAANLIYSLLFTR
                     IISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLVNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGASRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQEEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(9237..10946)
                     /locus_tag="TVR04_001600"
     CDS             complement(9237..10946)
                     /locus_tag="TVR04_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270276.1"
                     /translation="MLKDAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMGQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDKFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PTISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(10939..11388)
                     /locus_tag="TVR04_001601"
     CDS             complement(10939..11388)
                     /locus_tag="TVR04_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1270277.1"
                     /translation="MPRIIAELRELTHQVEQISEAIAKKYDLQHLSGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIEVIASNTDKRCKQVVLTSAGKAK
                     LPVLKECRKDIERYFFKEISREELLTVKKVIDQLKENIRVYKGDTDA"
BASE COUNT         3360 a         2917 c         2207 g         3054 t
ORIGIN      
        1 accagtgaca atttaatatt tattttaata atatattcca taatgatcac aaatcaagca
       61 gatcagccta cttgactatg atatctagct gcgcgctact ggacgtcacg ttgctgcctc
      121 aagcacacaa aaaaaagaat gaagcaaaca tcagatatct catctctgct tcattcatga
      181 tgttaccttt atgggcgata gccagctaaa ccaagctgtt agctacgata gtgcttaaag
      241 catattggca atatgctcaa tcgattgttc acgtccaagg aggtaaatgg tatttggcag
      301 ctctgggcca tgcatttctc cagaaacagc aatacgaatt ggcataaaga ggttcttgcc
      361 cttaatgccg gtttcttttt ggacagcctt gatttgtggg aaaatgtttt ctggcttaaa
      421 gtcctcatct gacatcgcct ctagcttttc cttgaaggcc ttcagaactg ttggaacagt
      481 ctcagctgcc atcacttctt tttcttttgc ggtcagctct gggaaatctg agaaaaataa
      541 atcagtcaat ggaacaatct catcagcaga gcttaattga ggctgataga gctcaactag
      601 cttctctgct ttttcagtca agcgacctgc tgcttcaaga aatggcttac aaagcgcata
      661 tacagcgcca agatcagcat gcttaaagta ctcattgctc atccagtcca tttttttctg
      721 gtcaaaggct gctggtgact tgctaagacg actctcatca aataaggcaa tcaattgctc
      781 acgagaaaag atctcagcct ccccgccagg attccagcct aaaagggcaa taaaattaaa
      841 gactgcctct ggcatatacc cttttttgcg gtaatcctca ataaactgca gggtattggt
      901 atcacgcttt gatagctttt tacctgtctc agaattaatg ataagggtca tatgaccaaa
      961 aatcggtgcc tcccagccaa gcgcctcgta aaccatcaac tgctttggcg tattggcaat
     1021 atggtcatct ccgcggataa cgtgtgagat ttgcatatcg tgatcatcaa taacaacagc
     1081 aaaattgtag gttggatagc cgtctttttt ctggattacc cagtcaccac cgacattgcc
     1141 accctcaaat acgatatcgc cttttaccat gtctgtccat ttgtaaacac cagcctcatt
     1201 gaccgctaaa cgaaccgtag gcacaatacc tgctgcttca cgctctgcaa tataggccgc
     1261 cttttcatct gctgacatgc caaggtattc attgacatag cgaggtgttt caccagctgc
     1321 ctcttgacgc tcacgctctg ctgccagctc ctcctcagtc acataagact tgtaagcctt
     1381 gccttctgcc aataattggt caatgtattg ttgataaagg gctagacgct ctgactgacg
     1441 ataacgctcg tgcgtctcag gactttcgtc ccaatctata ccaagccatt ttaaattttc
     1501 cagctgagaa cgctcgccgt cctcgacatg acgcttacga tcagtatctt caatacgaat
     1561 aataaagtca ccgccatgat gacgagcata aagatagtta aagagcgctg tccgcgcatt
     1621 tccgatatgt aaaaggcctg ttgggcttgg tgcatagcgc acacgaattg gtttagacat
     1681 tctttttctc ctatggtttc attgaaagaa gggatcctgg gctataaacc gttcctaggg
     1741 taggcttgtt ctatgagaaa atggtcgata aggaacaaaa atacagctaa tcccttggaa
     1801 atctaaagat ttcaatcgtt cctattatag cacaacttca agcattgggc gacaaaaatc
     1861 aacctagaac taggacagct gcataccgaa aatgcatgta accattttct gactacatgc
     1921 attgttttca tctacttctt atattttgat atcatcaact ggtcacattc agcttaattg
     1981 taacctgaat tgatttgaaa aagaccatac cactgatgag aaaatcgcta tcaaaaacgt
     2041 aaagatcctt gtacatttgg tgtgacttag cactaagata gctatagaag cagctcactg
     2101 gcaagcagtg ctgcctcttt caatagcttc atagcatgcc tagctataga tgttagtcag
     2161 gccattgacc tgcattgatg tcaagctaca ccccagcaaa gaaagtgaca atatactctg
     2221 gcaaccacga acctgtcata tccatttcaa tccatcaatt ggcaaggctt ggtttacttc
     2281 caactgctta atggccgcct gtgacaatat agctctgtaa aactccagca aattgctgaa
     2341 ggttcaggct ttgcacatag acatctccgt atccgctaaa ggtattgacc actccctcac
     2401 ctgtaccaat agactgcatt aagccatttt ccaaatgaat atcataatcc aaatcctgac
     2461 tccaagcaac tacatggcta ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt
     2521 taatcgaacc aaaagcattg accaataggg ttccttctcc ttgtgttgac atcacaaaga
     2581 agccaccctg accgctaaat aaggccttac caagtttttg gcgcttcatg gtgtagtgag
     2641 ctgagccatc taaagccaag aaggctccgt cattcaaacg gtattgatct acccctagct
     2701 caagagcaat aacctgacca ggcattgaag gggcaagcgc tagcttgcca ctaacatcat
     2761 tagcaatcgc ctgtgtgata aacatggatt ctcctgaaac cattgaacgg ccaatggcac
     2821 caaccagctt gccaagacct gagccacgcc cattgagctt ggtgtttaag ctgattgacg
     2881 gtgtgtggta aaccatactg cctttttgta gaaagacaga ctcccccatg tccaaatcaa
     2941 tttcaacaag aggaaactgc atgctgctgt caatagtata ggtcattcga ttataggcca
     3001 taacaccact cctttgtatg attttattga tacaatcaag tatagccttt tttggcagca
     3061 ttgtccacta gctactgtcg ccgccattcc taaccagtct caaagccata ctacaaaccg
     3121 atcagctgtc aggatttcgg catcgccacc tgagacatac gtccagtggc aacatcatag
     3181 accgcaccac taatgaccac gtcttttgga atcaacggtg attgctgcaa tatagccata
     3241 tcctcacgaa cacttgcttc cacatcagta aaggggagaa aatcacagtc agacacatct
     3301 actcccagag tatcatgaag ctgcgctgta aaggcttcat tggtaaaggt ttgtgcccca
     3361 caatccgtat gatgaagaac aacgatctca cgcgttccca gctgctgctg cgaaatcaca
     3421 agagaccgaa gcatgtcatc tgttatccgt ccaccagcat tgcgtaaaat atgggcgtca
     3481 ccaagcgcta agcctagggc ctgcgccaca tgcagtcttg agtccataca ggtcacaata
     3541 gctaccttag ttttgggctt tagaggcaaa tgagcagtcc catgtaaggc gacataggct
     3601 tcattggcag ataaaaagcg ttcaaaatat gacatgagta agatcctccc agactagtct
     3661 ttagactatc tcaaccttga gctgtctgtc tatcttatca tcttttgcct gaaatgtctg
     3721 aatgctgaac tgctttttaa tacaggcaga tagcactagc ctaactgaga ccagaggtag
     3781 gtgagccagc cttgacattg gaaacaagct cagcagccca ccctttgagc cgctaaagca
     3841 ggggcagcaa gcatgtaaca aaatcagacg attgtcgttt tgataaaaaa aaacgaaact
     3901 acggagacaa actgataaat tgctatttct cactatcagc cagcatgcta aactcttctt
     3961 agaaggcgtt tgcagtcact gactgctagg caacaatact aaattgagga gaataacaat
     4021 gaaacgaata aaaacaatct gcttattagc tgctgctgcg gtcctaacct tagctcctat
     4081 cagcacagga caaacacaat cacagaccat atatgcgagt caggttcttg aagaccagtg
     4141 tattaatcta ggtaatgggg taatcagatg tcctaataaa gatggggtag ggcaagattt
     4201 ctatgatcca gattatcaag cgccttcacg atcgccattt ttcacttgga tttcaggctg
     4261 gtttaacttt atatggcagt ggtttaaaag cttctaagat ctactaatac gctatccata
     4321 tcacaaggct cttagagact agctctctaa gggcttttta gccttatgag acaccataag
     4381 aaagctacca atagctactg gcaaaccaaa aagggctaga aataactgtc ctaaccctca
     4441 catcaaaagc agcaagccta agcaaagact gcctttaaga cctctcctac tgtcattaca
     4501 ccaacaacct caatcccact tggtatgtca atgccctgca atgagctttt aggagcgtaa
     4561 agcttggtaa agccaagctt tgcagcctca ttgatccgct gctcaatacg agtgacccgc
     4621 cgaatctcgc ccgtcaagcc aatctctcct aagaaggcct cctgagggtt ggttggtttt
     4681 tccttgtagc tagaagcaat agccacagca actgccaaat caatagcagg ctcatctagc
     4741 ttcacacctc ctgctgattt gaggtaggca tcttgatttt gtagcagcag gccgcagcgc
     4801 ttttctagga cagccataat caggctaaca cgattaaagt ctaatccagt agtggttcgt
     4861 ctagcattgc caaaaacagt cggtgtcacc aaggcctgca cctcagctaa aattggccta
     4921 ctgccctcca ttgtaacgac aacagccgag cctgttgcgc cgtccagacg ctcctctaag
     4981 aaaacctgac tggggttgag aacctccacc agaccgcctg attgcatgtc aaaaatacca
     5041 atctcattgg ttgagccaaa acggttttta acagctcgca gaattcggaa ggtgtggtgt
     5101 ctttcccctt caaaataaag cacagtatca accatatgct ccagcatgcg gggccctgct
     5161 agggtcccct ccttggtcac atggcccacg ataaaggtag cgatatgatt agactttgca
     5221 agctgcagca attcggcagt aacctctctc acctgactga ccgagccctg aacacccgaa
     5281 atctccggac tcatgatcgt ctgaatagaa tcaataatca aaaaatccgg ctgaatggct
     5341 tcaatctctg cccgaatagc ctgcatattg gtctccgcat agaggtaaaa atcattgtcg
     5401 gtctgtccca aacgatcact gcgcatcttg atctgctctg ccgattcctc tccagagaca
     5461 tataaaacag ttcccttatc cgcaagctgg atagaaacct gcaagagcag cgttgactta
     5521 ccaataccag gatcaccacc aatcaaaacc aagctccccg gtacaacacc tccgcccagc
     5581 acacgattga actcattcat ctcagtctgg atacgctggt agcgaacgcc attgacatgc
     5641 tttagcttga tgggcttact cttttctcca gtcaggctaa tacgggcatt tttgacgtcc
     5701 ttgacctctg tctcctctac aaaggaagac caagcagagc aattagggca gcgccccaga
     5761 tatttgggtg actgatagcc acattctcca cagataaacc tcgccttttt cttagctata
     5821 acacatttcc tccttgaatc taagcatcaa ctggctacaa gcacgtgaag cagcctgcta
     5881 ataccttatc ctcctgtcga accaaaacca cctgtccgct caccaccagc ctgatcacca
     5941 tcagcaatca aaaatggcat aaacacccct tgaacaatac gctcaccgac tgctaacgta
     6001 acggtttgat ccgtaatatt tttcatctga gcaaaaatat gaccttcatt cgcagggtta
     6061 ccatagtagt caccgtcaat aacacccaca gaattgatca gcaccagtcc ttttttgcga
     6121 ggattgctgg agcgatcata gagataaagc acctcaccgt cttgcatgta cgccttgacc
     6181 cccgttggca caaggacaat ctcacctggt gcaatgctgg tctcctctgc aacagatagg
     6241 tcatagcctg ctgcatgagc tgtctcacgt tttggtaata gctcagtatc agtaaagcct
     6301 gacacaagct caaagcctcg aatccttgtc atgattaatc ccaagagcct tggctagtca
     6361 ctacagcagc tctaaggctg ctgtatagta cagctaccca aagctctctt ctcctttttc
     6421 ttttttagtc ttcttattat aagatattcg caaaagaata gcaaaaaagt gagggctgca
     6481 cccctctata ccgcaaaaaa atgcaggagg gctaaatctc cttgccagca tagctaaatc
     6541 gaatccttgg aaaatcagcc tccaaatcct tatctaccag aaaagccttg gcgtcctttt
     6601 ttacctgaac caaatcaaca ccttgtattt ttgcagcata gacgcagcca caatagcatt
     6661 gacgataaat atcgtactcc tcacacattt cgaccgacct gcgatagcca ttatttttct
     6721 taaaatcgct cggtaaatac ttggtggtgt aaaccttttg cacatcaatg cctacatcgt
     6781 taatcgtctg tgagttttta tgagggctga tggtcaaggc actagcaaaa taatcaaagc
     6841 ccagctccac agccttttgt gccgtcttgt ccaagcgata atcaaagcaa acacgacaac
     6901 gatcgccccc ttcaggctct ttctccaagc ctcggacagt cttgataaac tcatttggaa
     6961 cataatctgc ctcgataaac tgcacgctat tacctgtttt atcgttgaac tctgctacaa
     7021 acttctgagt aacataggcc ctacgatggt attcgtcctt ggggtgaata tttgaattgg
     7081 caaaataaac cgtaatatca gcatactggg tcaaatattc tagcgtatag gtcgagcaag
     7141 gagcgcagca gacatgcatc aaaatcttgg ggcgcacgtc ctctctagcc caggccttgg
     7201 tcatctgctg catgacccga tcatagttta ttttctggtt tggattcatt ctagctagaa
     7261 tctcttgcaa gtcaatcatt acatcttcta ccttctattg tctgtcactt ttattatagc
     7321 acattgcctt gacatgcttt gcatcaaaaa actccgccaa agcggagtcg atcggcaaaa
     7381 gctgttttga tggtttttaa gaataacaac agcagcttat gtaatgatca tttttagaag
     7441 ctactcaaac acaaactgat tgtgataaag ctcggcataa aagccctttt gccttagcag
     7501 ctcatggtga cttccctgct caataacctt accgtccttt agaacgatga tttcatcagc
     7561 atttaaaatg gtttttaggc ggtgggcaat cacaaagctt gttcggcctg ccacgatagc
     7621 ctccatagcc ttttgaatct tgctttcggt aacggtatca acgtttgatg ttgcctcgtc
     7681 caaaatgagc acctgtgggt ctgttaacag cgtacgagca attgagataa gctgcttttg
     7741 acctgttgaa aagacattct catcatcaga tacctgagtt tggtagccat caggcagaga
     7801 catgataaac tcatgaatat gcgtcgcacg cgctgctgtc tcaacctcct cttgactaat
     7861 cgtttgatta ccaaagcgga tattatcagc aatagtccca gaaaacaaga ctgactcctg
     7921 taggacaata ccaacccgct gacgcagact atccaagtca tattccctaa tatcacgccc
     7981 atcaaaggta atagagccag catcaacatc ataaaaacgg ttaatcagat tcatgatagt
     8041 ggttttacca gaccctgtcg ggccaacaac agcaaccatt ttcccctttg gagctgaaat
     8101 cgacacatct gacagaattt tttgtcccgg cagataacca aagtcaacat gcttaatctc
     8161 aaccccttct tttaatgctg taaagacagg agcatgctca ggacggacct cttctttttc
     8221 gtcaaacatt tcttgaatac gactagcacc ggtaaaggcc agctgcaact caccccaact
     8281 ggaggcaatc tgcataatcg gttgataata ctgctgtgaa tactgaacaa aggtcacaac
     8341 caaaccaaga gcagcagctg ttgacatgga cttgtctcca aggacaatgg ttgagccggc
     8401 aaaaatgaca atagctgtat tgaccaagct cattccattc atcacaggaa acagcaggcc
     8461 ggcaaagaga cgccccttaa aggttgctgc acgcaccctc tcgttgtgct caataaagcc
     8521 atcaatagca tcctgctgca ccccttgaac aataatagcc ttttggcctg aaatcttctc
     8581 gtccatgtaa gcattcaagg cactgacctc cttttgctgc agatcagtgt atttgcgggc
     8641 cattgtaatg atgacaacga gaagaataag cgccacaggg gttgaggcta tcgttaccaa
     8701 ggccaagcga ctatcctgcc taaacatcat cagcactaga ccaatataca aagcaatatt
     8761 tgtcaagacc tgaatcagag attggttcat ggagttttga atattatcaa gatcactggt
     8821 aaagcgtgat agaatagcac catccttgtg actatcaaaa aagccaactg tcaagcgctc
     8881 caatttgcca aataagccct tacgcatgcg attggtcgaa tgcgaaataa tccttgtaaa
     8941 gaggagacta taaataagat tggccgctgc tataaagaga taggtcaaca atagctttcc
     9001 cataaccgtc ctaaaaggcg ccatagaggg ctcaactaag ggctgacccg tcattttgct
     9061 aagagcctga gccttgtaat agcgctgcac ccattctccc agctcagcta gagagtctcc
     9121 caaaaagaca ggggccttaa cctgcaggta ggttgccagg acaatagcaa agaatatcac
     9181 aacaaaagag agcttataac gtttaaaata aaaccagaaa aatcgcagga tcttcattag
     9241 ttctcctctc ttcccttttg agtttcgtaa atttcacgat aaatcggatt ggaagcgacc
     9301 agctcagcat gcgtcccttc tccaatcaat cgaccattat caagaacaag aatcttatct
     9361 gccttgacaa ctgacgatat tttttgtgcg atgatgactg ttgttgtctc tttgagctcc
     9421 ttgttcaagg cctcctgaac aagcttttca gatttggcat ctaaggccga tgtcgaatca
     9481 tcaagcacca aaatcttagg attattaatc acaccacgag caatagacat tctctgcttc
     9541 tgaccaccag aaaaattatt gccgcgctct tctacctcac tctggtagcc agcgtccata
     9601 cggtcgataa attccttggc ctgcgcaatg cgcgctgcat tttctaaagc caattggtca
     9661 gcatagggat tgccctgacg cagattgtcc gcaatagtcc cagaaaaaag aatagccttt
     9721 tgcagcacaa tagagactgt atcgcgcaaa gtctcttgac tgatagttgg caaagccttt
     9781 ccaccaatca ggatttgccc ttcctgtggg tcaaacaaac gcggaatcag ctgcgcaagg
     9841 gtcgacttgc cagcacctgt cgcaccgaca ataccaacca tttgaccggg ctcaacctca
     9901 aacgaaatat gctttagagt ggcttcactg tcatttggat aggtaaagct cacatcatca
     9961 aagacaatac tgcctgtcag ctcctcctgc tcatggttaa caaaggtcat agcaggctct
    10021 gtttctaaaa tctccctgat ccgaccaatc gaggtcaagg cacgactagc ctgcattccc
    10081 ataaaaccaa ccatcgtgat cgcaaagctg atttgtccca tataggtcat aaaggaagcc
    10141 atatttccaa taacagcagg gtctgttttg accagccctg aaaccagata caaggacaaa
    10201 taaatagcca tgtaagacac caacatcaaa ataggctgca tgattgaaaa gccatagccg
    10261 ataaacaaat tcaagcccag taggtcattt gaagcttcct taaatttgtc atactggctt
    10321 ttttcctgaa caaaggactt gaccacacgc acaccgcgta ggttttcctt agcaatctgg
    10381 ttgatcctat ccatcaagcg ctggaagatc ccaaagcgag gacccatctg gcccatcacc
    10441 agcccaatga ctaccattgt catcacaacc acaagcacca agacccacca aaggctcggt
    10501 aaggcctgca ccgctaaaat aaaggcaccg acaaataaaa tcggcaagcg caacaatatc
    10561 tgaaaaagca tcatcacaaa gttttggatt tgattaatat catttgtcat tctaacgaca
    10621 agatttccag cattgaaggc ttccacattg gcataagaaa aggattggat ctttctaaag
    10681 gtctgctcac gaatatcagc agatacccct tgagcaatct tggcagacaa gatggtattg
    10741 accgcacctg acaccaagcc aatccctgct atcactaaca gccaaaaacc cacctctgca
    10801 atccttgtct gatcattttc cataatagca gctagaacat ctttgaggta atgcggctgg
    10861 agcagggcac tggctacgac cccagagatc atcactaggg acagagccgc ataccattta
    10921 tacttcatca cagcatcttt aagcatctgt atctccttta taaactcgta tattttcttt
    10981 cagctgatca ataacctttt tcaccgtcag cagctcttct cttgaaattt ccttgaaaaa
    11041 atagcgttca atatccttac ggcattcctt tagtaccggt agcttagcct tacccgccga
    11101 ggtcaaaaca acctgcttac agcgtttatc cgtattcgaa gcaataacct caataaagcc
    11161 atttttttcc atgcgcttca ccagattact cgtaaccgac ttggatattt gaagctcctt
    11221 ttcaatgtcc ttgacaaaaa tatctctgtc ttgatggcaa tgcaaaaaga caaggacatg
    11281 accctgtgga cctgaaagat gctggaggtc atacttttta gcaatcgctt cgctaatttg
    11341 ctcaacctga tgggtcaatt cacgaagctc agcaatgatt cttggcattt ccttcctcct
    11401 tagttctcat ggtaaccatt ttagttctct tggaaactat tgtcaattaa aaagacttac
    11461 tatttgacca tctccttttt taacctatcc tttgctagca ccactaagct aacagactaa
    11521 gccagcagac cttttcta
//
LOCUS       DARYSY010000056        11425 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYSY010000056 DARYSY010000000
VERSION     DARYSY010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11425
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            98..394
                     /locus_tag="TVR04_001602"
     CDS             98..394
                     /locus_tag="TVR04_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WXG100 family type VII secretion target"
                     /protein_id="HEL1270278.1"
                     /translation="MSGQIRVSPETLQSRAREYGKASNDITTILNNLQRLQDTLRTEW
                     EGAAFQGFDNQFNELKPKVQNFAELMQQINTQLDKTAQAMQQNDQELSRNFGLH"
     gene            463..3651
                     /gene="esaA"
                     /locus_tag="TVR04_001603"
     CDS             463..3651
                     /gene="esaA"
                     /locus_tag="TVR04_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EsaA"
                     /protein_id="HEL1270279.1"
                     /translation="MSKKTLMVLTGLLLILTMSVSFFAIVKPSSIGMEASDQAAKKHT
                     IRIAAVNEDAGMTYNGQPVNIASALLASFSSHTDYDVELVSRSIAERGLENNVYQLML
                     VLPSKFSEEALALETTNPNSATFHYQITSDQSLTVKQAEQAVIDLKSLFNKDLITIYF
                     SSIIGNLQSAQSQMVDAISNEDKVLSAYQLHLINPLSLHSQQFTGLGTAPNELLSNYL
                     TFNKELNRSTDAFKSIIDVDKTYESELAQIKAQQEGWQQSLSAREDKLLAYDKGFSNL
                     TIEEQLAKLTEINAYVTEKLNEPAIWKDTLDKATAYNQDITSLLKYLRGLNTKITTTL
                     SNYDANIKQAIESSLSHRDPGAGGMGKTLGSYMESLKASMLLQTKQKWPAFWYSDEMI
                     AAFPLSEQDRQHLKNINAFMRWYSHKYLLPLPQLRASSLEGLYLAQVKEDRKRHLAET
                     RSLTISGVKGRAKQLDITVPKHYQLEVERHLLRSLGEGHYQIDLEDQDTSDVTIQYRL
                     SVTDSDVTLFSPVVVSAQLLTSEEVTALNTEDDEDAADEDYVPDSNGPLSKRRRGSKS
                     SATATRLTRKATRAGESAQQVIDRTYTVQDVIADTTYTPTENAKALFQDVQSYLQLSG
                     LATAYFGRDLSEGVYSETAITPREGSVAALANGDDLKAIMTNLIKQATVEALKADLTI
                     SEEELASIEKRRVSVEELTKTVEGLRAATTDLKTRLSQILEELGAVHKTLQEKPVFTT
                     TEKWDNTDMVAVSMTMNSDLSKLMAASRVLMDNTKSNQIVSETIEGTIKQLSNDVTTL
                     EKNGEALKGHVTELKDTMTGDYGSNAAFLKAFTAVLSNTKKGNAKNTAVYEYLSNPVD
                     ASKIDRVLSAAAGLKAVRQDERSGLLIILITYLTSLAVAYLFQQGAGLQGSLRVTQRL
                     AWKNAVAPMTYLSGMVLLIAPVIAVISGYRLDFSLGQLAFFALLLAVMMLVMTYTLNL
                     LLEKTRSLGFLMSIGILMLYLITAAQLFDAYYARSPQLLVRLSPLTYLELMVRAFINR
                     QGGLTIPMTILVVLALALAVANAYHYRQVKDR"
     gene            3617..4141
                     /locus_tag="TVR04_001604"
     CDS             3617..4141
                     /locus_tag="TVR04_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1270280.1"
                     /translation="MLTITDRLRIGEEAMMRKIMTLLVLAGLSLGLSSAVLANDGSLH
                     IDTSLNQGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTKNHLFMTHI
                     DSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGAVLTGYSLT
                     RGRLSRQKHKRHHE"
     gene            4458..4700
                     /locus_tag="TVR04_001605"
     CDS             4458..4700
                     /locus_tag="TVR04_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
                     /protein_id="HEL1270281.1"
                     /translation="MENYISISLDCSHFFPQEFDLRVPRTMTFKELLQIVSDAYGLGF
                     QVVNPSARNEQGGQLMTSTSRMDTLKNGALLVLENL"
     gene            4703..5860
                     /gene="essB"
                     /locus_tag="TVR04_001606"
     CDS             4703..5860
                     /gene="essB"
                     /locus_tag="TVR04_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1270282.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYALLASEHSLFVPSKLEQAS
                     DKLILEASLDDMYDWSALETMIVEEKLRHLLNLSELFDQLSDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMDGKLPFYKGN
                     LFCEAVAKAEMLQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPREEKAAGSSSDKE"
     gene            5872..10248
                     /gene="essC"
                     /locus_tag="TVR04_001607"
     CDS             5872..10248
                     /gene="essC"
                     /locus_tag="TVR04_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1270283.1"
                     /translation="MIYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEKSYSTGKHCVALSDEVTVTLLIFEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVPYYLNGKWTKGKQPLKASDELVFSQGLVLSFQDQLLSVQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFQIDYSDSELTKHHEKARQRVQELIAYYQVTAQVPIQNAITSPIGYIGA
                     RKVVIEQVQQLMMQIATFQSYHDVQFIPIFREEELPLWNWSRWLPHTKLKALNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEIFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITDNGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PEQQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRVVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREEVVPA
                     GFTFKKPILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPNQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            10261..10590
                     /locus_tag="TVR04_001608"
     CDS             10261..10590
                     /locus_tag="TVR04_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1270284.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            10594..11028
                     /locus_tag="TVR04_001609"
     CDS             10594..11028
                     /locus_tag="TVR04_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1270285.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            11030..11314
                     /locus_tag="TVR04_001610"
     CDS             11030..11314
                     /locus_tag="TVR04_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1270286.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQAEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
BASE COUNT         3285 a         2249 c         2708 g         3183 t
ORIGIN      
        1 aacaaaataa aaaaattaaa caaaatatac acaaaaactt gtaaaaattg taacaatatg
       61 ttagtattaa gttattaaat agttaaagga gacaattatg tcaggacaaa ttcgtgtatc
      121 gccagaaacg cttcagtcac gtgcgcgtga atatggtaaa gcatcaaatg atattaccac
      181 tatcttgaat aaccttcaac gtcttcaaga tacccttcgg acagagtggg aaggtgcggc
      241 attccaaggc tttgataatc aatttaacga gttgaagcca aaggtacaaa actttgcaga
      301 gctaatgcag caaattaata cacagcttga taaaactgca caagcgatgc aacaaaatga
      361 ccaagagttg tctcgtaact ttggtctgca ttaaacataa gaaactggta aggttgggga
      421 gggctcctca gcctttttta ttttagcgat taaggagcag caatgagtaa gaaaacacta
      481 atggtattaa cagggttact gttgatatta acaatgtcag tatctttttt tgctattgtc
      541 aaaccttcat ctattggcat ggaagcttca gatcaagcag ctaagaagca taccataagg
      601 attgcagcgg tcaatgaaga tgcaggcatg acctataatg gccagccggt gaacatagcc
      661 tcagctctat tagcgtcatt ttcttctcat acggattatg atgttgagtt ggtctcgcga
      721 tcaattgcag agcgaggact ggaaaataat gtttaccagc taatgctagt gttacctagt
      781 aaattttcag aagaggctct agctcttgag accacaaatc caaactcagc aacctttcat
      841 taccaaatta cctcagatca atccctaaca gtgaagcagg cagagcaggc tgtgattgat
      901 ttgaagtcct tgtttaataa ggatttgatt acaatttatt tctcaagtat tattggaaat
      961 ctccaaagtg ctcagtctca aatggtagat gctatatcaa atgaggataa ggtgttatca
     1021 gcttatcagc ttcatttaat caatcctttg tctctgcatt ctcagcagtt tacaggctta
     1081 gggacagctc ctaatgagct actttctaac tatttgacct ttaataaaga gttgaaccgt
     1141 tcaacagatg cttttaagtc aattattgat gttgataaga cctatgagtc tgaattggca
     1201 cagatcaagg ctcagcaaga gggctggcag caatctctta gcgctcgtga agacaagcta
     1261 ctagcctatg ataagggctt ttctaatcta accattgaag agcaattagc aaagctgact
     1321 gaaatcaatg cttatgtgac agaaaagctg aatgagccag ccatttggaa ggatactctg
     1381 gataaggcaa cagcttataa ccaagacatt acaagcctcc taaaatacct aagagggcta
     1441 aataccaaga ttaccaccac cctttctaat tatgatgcca atatcaagca ggcgattgag
     1501 tcctccttgt ctcataggga tccgggagct ggtggtatgg gtaaaacctt aggaagctat
     1561 atggaatcac tgaaggctag catgctattg cagaccaagc agaagtggcc ggcattttgg
     1621 tatagtgatg agatgattgc ggcttttcct ttgtcagagc aggataggca gcacttgaaa
     1681 aatatcaatg cttttatgcg ttggtatagt cacaagtatt tgctgccctt gcctcagctg
     1741 agagcctcaa gccttgaagg gctttatctt gctcaggtca aggaggatag aaaaagacac
     1801 cttgctgaga ctagaagtct tacaatatct ggggtaaagg gaagagccaa gcagcttgat
     1861 attaccgttc caaagcacta tcagctagag gttgagcgcc atttgctgcg tagtcttggt
     1921 gaggggcatt atcagattga ccttgaggat caggatacct ctgatgtgac tattcagtat
     1981 aggctgtcag tgactgattc agatgtgact ctttttagtc cggtagttgt ctcagcacag
     2041 ctgctgactt cagaagaggt gactgcctta aatacagaag atgatgaaga tgccgcagac
     2101 gaggactatg taccagattc taacggacct ttgtctaagc gtaggagagg gtctaaatcc
     2161 tctgctacag ctacgagact gacaaggaag gctacaagag ctggtgagtc agctcagcag
     2221 gtgattgatc gaacctatac ggtacaagat gtcattgcag ataccaccta tacgcctacg
     2281 gaaaatgcta aggctctttt ccaagatgtt caatcctact tgcagctatc aggtctggct
     2341 acagcctatt ttgggcgtga tttgtcagag ggtgtctata gtgagacagc tatcacacca
     2401 cgtgagggct ctgtagcagc cttagctaat ggagatgacc tcaaggccat tatgactaat
     2461 ctgatcaagc aagcaacagt ggaggctcta aaggctgatt taacgatttc agaagaagag
     2521 cttgcaagca ttgaaaagcg tagggtcagt gtggaggagc tgacgaagac cgttgagggc
     2581 ttacgtgcag caacaactga cttgaagaca cgtctaagtc aaatcctaga ggaattagga
     2641 gcggtgcata agacgcttca agaaaagccg gtctttacta ctacagaaaa atgggacaac
     2701 acagacatgg tagctgtcag catgaccatg aatagtgacc tttctaagct aatggcagct
     2761 agtagggtat tgatggacaa taccaagtcc aatcaaatcg tttctgaaac cattgagggc
     2821 accatcaagc agctatcaaa tgatgtaacg acccttgaaa aaaatggaga ggcactaaag
     2881 ggccatgtga cagagctaaa ggataccatg acaggggatt atggctccaa tgcagcattt
     2941 ttaaaggcct ttacagctgt tttaagcaat accaaaaagg gaaatgccaa aaatacagca
     3001 gtctatgagt atttatcaaa tccggtagat gcctctaaga ttgatagggt gttatcagca
     3061 gcagctggtc tcaaagcagt taggcaggac gagcgctcag ggcttttgat tatcctgatc
     3121 acttacttga ctagcttggc agtggcctat cttttccagc agggagcagg tttgcagggg
     3181 agcttaagag tgacacagcg tcttgcttgg aaaaatgctg tcgcaccaat gacttattta
     3241 agtggtatgg tcttattgat cgctccagtg attgctgtca tttcgggcta tagattggat
     3301 ttttcgctgg ggcaattggc tttctttgct ttattacttg cggtcatgat gttggtaatg
     3361 acctatacgc ttaacctgct gctggaaaaa acaagaagtc tgggattttt aatgagcatt
     3421 ggtattctga tgttgtatct tatcacagca gctcagctgt ttgatgccta ctatgctcgt
     3481 tcgcctcagt tactggttag gctgtctcct ttgacctatt tggaattaat ggtgagggcc
     3541 tttatcaatc gtcaaggagg actaaccatt ccaatgacta tattagttgt tctagcctta
     3601 gccttggcgg ttgctaatgc ttaccattac cgacaggtta aggataggtg aggaggctat
     3661 gatgagaaaa ataatgactt tgctggtttt ggctggcctt agccttgggc tgagctctgc
     3721 tgttttggca aatgacggtt ccttacatat tgatacctct cttaatcagg ggggtgagaa
     3781 aaaagacatt agctacatcg agcaagaggg cgatctgtct gccctatttc aatcagagac
     3841 agacttaagc attaaaaaga aacagcagca tcgaaaagaa actagtcaga cgaccaagaa
     3901 tcacctattt atgactcata ttgatagtga caaccttgtt gcaaggtatc agccactctt
     3961 atttaaccca gagcagcgtc tggcagcaac agatgaccag tatggtgttt tgctcgctca
     4021 aaaaactatc ggcatcactt ggcaaatgct ggccatactt cttgtgggag ctgtactgac
     4081 tggctattct ctgactagag ggcgattatc aaggcaaaaa cacaaaagac atcacgagta
     4141 gaatcgtctg ccaagagtat ctactcactg aaaatagagt gctagcttgg gagacttcct
     4201 aatgctgcat ttataagaaa aggccctcag ctgttttgac agtattgggc aaggcctcag
     4261 ggtctgtagc aaatatgaag agctgctttg atcagcaggt ggcaaatcag tcaatacaaa
     4321 tgcttgaaag cctacctgct gagaaaagtg tgtgttctac gatactttag tgatgtgaat
     4381 cacctcaaga ggcttttagc tagcttggca ggtgatgtca ggtgacatgg aaacttatca
     4441 ggaaagggct aatttttatg gagaattata ttagtatcag tcttgattgc tcgcattttt
     4501 ttccacagga atttgatttg cgggtaccaa ggacaatgac ctttaaggag ctattacaaa
     4561 tcgtatcaga tgcttatggt ttgggatttc aggtggtaaa tcccagtgct agaaatgagc
     4621 aaggtggtca gctgatgaca agcaccagtc gcatggatac cctaaaaaat ggtgcactgt
     4681 tagtattgga aaatttataa acatggagaa aaagatgaaa acaataatac gtgagctatt
     4741 ggttgaggat gttaaaggag atgctgaggt tgcttatgcc ttactagctt ctgagcattc
     4801 tctttttgtt ccttccaaat tggagcaggc ttccgacaag ctgattctag aggctagtct
     4861 tgatgacatg tatgactggt cagccctaga gacgatgatc gttgaggaaa agctaaggca
     4921 tttgctaaat cttagtgaac tgtttgatca gctctcggac tcaaagttca cctacagctt
     4981 tacaccagat aatctggtct ttaatcgtaa tgcagagcca cagttgattt ttcggggaat
     5041 caaggatcag gttcctcctt accagccgct tgagcgtgag gtctttgtga atacactgaa
     5101 atgtatgaca attgccttgc ttgataaaaa gaccagctat gacgctctga tggatggcaa
     5161 gcttcccttt tacaaaggca atcttttttg cgaagcagta gctaaggctg agatgctgca
     5221 ggagttgcag gagcttttag cgacaaagta ccatgaggag caaaaagaca ataaagagca
     5281 tttttctcgt gttgctaaca agacgatatc gcgcttgaaa ttgaccacca tttgttcatc
     5341 agtgcttgct ttgttgtctt tggcgggcgt tctttatttt ctattgtttg ctatgcctta
     5401 tcaggaaatg gttgctagtc tgcgtatggc ttttattaat caagactatt ctaaggttat
     5461 cacaacagcg aagcatacag acagcaaggc cttaagccag ggtgataaat atattgtggc
     5521 ttactctgtc ataatgacag agcctctaac agacaagcaa aaggaggaat taagtaaaat
     5581 atcgaaccag tctaatgaag attatttacg ctattgggtg ctgattggtc aagcgaggat
     5641 agatgatgcc atggatattg cgagctatct ggacgacccg cagctcttga tgtatggctt
     5701 gactaagaag attgatgatg ttcagcgaga tcctaatctg acagcagagg cgcgtacaga
     5761 gcagcttaat agctataaga gcaaattaga cgagctcaaa aaggcctacc taacccctag
     5821 agaggaaaag gcagcaggct ctagcagtga caaggagtga cggaggaatt tatgatatac
     5881 cttatttatg atgacaatgc ctatcacctt tattcggata ccgtttatca gttgggacct
     5941 tcatcagggt ctgatatttt cctgcccttg ctggaggata ttaccttatc agtggaggga
     6001 tcaggtgttg tcctactgga aaagagctat agcactggta agcattgtgt tgctctttct
     6061 gatgaggtta cggtgacctt acttattttt gaagctgtca ctaaatacct gctgccagac
     6121 tcctcgcttt acatttcagg agagactacc gcagcacttc aattgcttga ttaccctagt
     6181 gagctggtgc tgaccttgga ctctgattct gccagctgct atagcccagt gccctattat
     6241 ttaaatggta aatggacgaa aggcaagcag cctcttaaag catctgatga gcttgttttt
     6301 tcacagggct tagtgcttag ttttcaggat cagctgctat ccgttcagtc cttgtatgct
     6361 atccagacgg cattactgcc tcttacagag gcagtagctg aggatagagc cagtgaattt
     6421 catcgttctc ctaggattat cctgcgtgag cctgagggaa aggtaacgat tgcttctgtc
     6481 cccacagatg atgagggaaa aagacagtct ttattaaagc tgatcataac gccgcttgcg
     6541 atgattgtct ttacagggct ctcctatgtc tttttccgag gtgggggcat gctcatgatg
     6601 atgatgggaa tgtctgtgat tacgattgga agctccattc attcttactt ttcagataaa
     6661 aaatggcata aagaagccca gcagcaaaaa atcaaggatt atctagccta tttggatact
     6721 aagtatgtgg agctagccgg ctatcgtgaa gagcaaatcg aagcactgct ttatcattac
     6781 cctaatatga cgactattct ggagatggca caaaaaacag atcgccgtat ttatgagaag
     6841 gctccatatc attttgactt tttgacctac cgcttggggc taggtgatac tccagccagc
     6901 tttcaaattg attattcaga ttctgagctg accaagcatc atgaaaaggc aaggcaaagg
     6961 gttcaagagc tgattgctta ttatcaggtg acagcacagg tgcctattca aaatgcgatt
     7021 accagtccaa ttggttatat tggagcacgt aaggtcgtga ttgagcaggt ccagcagctg
     7081 atgatgcaga ttgctacctt ccagagctat catgatgtgc agtttattcc tattttccga
     7141 gaagaagagc tgccattgtg gaattggagc cggtggctgc ctcatactaa actaaaggcg
     7201 ctaaatagtc gtggctttgt ttatagccag cgaacacgtg accaattgtt gacctcgctt
     7261 tatcagctga tcaaggagcg gcaattagat agtgagcagg ataaggggac agaaaagcaa
     7321 tacactccgc attatatcgt gctgattact gacatgagcc tcatgcttga ccacaatatc
     7381 atggaataca tcaatgagga tttgtctcat ctaggcattc attatatttt tgttgaagag
     7441 gtcattgaaa gtctccctga gcatgttaaa acagttattg attatcgtgg agataagcat
     7501 gctcagctca ttttgcagga ggggctctac ctcaataagg cctttacccc gcttcagccc
     7561 ttatctatga aggataagga gatctttgct agacatatgg cagggattaa tcacgttgaa
     7621 accttacgta atgcgattcc aaatagtgtg acctttcttg aaatgtatgg cgttaacaag
     7681 gttgaggagc ttaatctctt aaagcgctgg aaggaaaatg aggcttatca gacaatggct
     7741 gttccgcttg gggtgcgtgg tcgtgatgac atcttgtacc taaaccttca tgaaaaagcc
     7801 catggaccac atggcttgat tgcaggaacg actggatctg gtaaatcaga gctggttcag
     7861 tcttatattt tgtccttggc ggtgaattat catccctatg aggttgcctt tttgctgatt
     7921 gactacaagg gtggtggtat ggccaatctc tttgctgatt taccacatgt cgttggaacc
     7981 attaccaacc tagatggcaa tcaggccaat agggctttgg tatcgattaa ggcagagctg
     8041 aaaaagcgtc agcggatttt ccttgaaaat gatgtcaatc atattgatca atacactaag
     8101 ctattcaagg aaggacgagt taaggagcct ctcccacacc tgttaatcat cagcgatgaa
     8161 tttgcggaat taaaggccaa tcagccagaa tttatggacg agctggtctc aaccgcccgt
     8221 attggtcgtt ctcttggtgt taagctcatt ttagcaacgc aaaagccaag tggtgtcgtt
     8281 aatgaccaga tttggtcgaa tgcgaagttt aaaattgcct tgaaggttca agatgttgca
     8341 gattctcgtg aggtgattaa aaccccagat gcagcagaga ttactcaggt tggtcgtgct
     8401 tatctccagg ttggtaacaa tgaaatttac gagctgttcc aaagtgcctg gtctggagca
     8461 gactacaatc caaaaggacg acataccatt cagcatgaga caacagtcta tgaaatcaca
     8521 gacaatggtc aataccaagc gattaacaag gaccttagtg gacttgacaa gaagagagaa
     8581 gcaaaatcca tgccaacaga gctagatgcg gttgtagcag aggctcagca gctctttgag
     8641 gacctgcata ttccaaaggt ggccagtcct tggctaccac ccctttcaga aaaaatctat
     8701 gccagtgatt tgcaatcgac gcatttcaag gactattggg gacagacaca ggacttgcag
     8761 cctgttttga ttggctatca ggatattcct gagcagcaag agcagtcccc gctctatttt
     8821 cacatggaaa aggctgggca tatcctctta gtgtctagtc ccggctttgg gaagtctacc
     8881 ttccttcaag gctttgcttt agatgtgatg cgaaagcaaa caccggcaca ggctcatttt
     8941 tacctctatg attttgggac aagtggcttg attgcgcttt ctgattttcc acatgtggca
     9001 gattacttta ccctagatga gacagacaag atcatgaaat cacttcgtta tttaagtgaa
     9061 gaaatcaaga cccgtaagca tgccctatct aaggctaagg caaccaacct caatcagtac
     9121 aatcaattat ctaaggatac cttcccagct ctttttgtca tcattgatgg ctttgatagt
     9181 gtcatggacg caccatttgt agatgctgtc tacaatgtct taaacgttat tgcgcgtgat
     9241 ggggcttcct tgggaatgta ccttgttgtg accttatcaa ggcttaatac catgaggcta
     9301 cagctgcagt ctaactttaa gaccaagcta tccctcttct tgtttgataa tagtgattta
     9361 tcaagtgtgg ttggtcgctc aaatatccca ctagatgata tcaagggacg agctatcatg
     9421 aaacgtgacg acattatcca atttcagatt gccttgccat atagcagtga gtactataca
     9481 gattatatgg cggaggtaaa aagagaggtc gaggcgatga gggttgttta tcaaggtgct
     9541 ttgccagcgg ctattccaat gctgccagaa aaggtcacac cagatatgat agcagccatg
     9601 tcagactctg cacaggactt tgtgattggt ttggagcgag aggaggttgt tcctgctggc
     9661 tttaccttta aaaagccaat actgatggcc tctgatagcc cagcctttgt ggctaactat
     9721 tataagctgc ttgattttca gttgcagcgt ctggctgacc agtatcgtac ggttatttta
     9781 gatcctagtc agcgcattgc aaggcaattc tttgaggata gtcaacgctt tagcacagcc
     9841 ttagatgttg gagacactct aagggctatt gtagaggact ttaaaaagcg tcttgcagcg
     9901 cctaatcagg attatcagaa atggctagtt gtgattcctg atattgcagc tacagcactg
     9961 gcagcaggga ttagcgagga agactttaaa cagcttgtga ccgagggcag ccagtatggg
    10021 gtcacgctta tctttgtcgg agcttatcag gatctggtca ataataccta tgataacttt
    10081 gtgaagcttg caaatcagct cattgagcag gtctttttag gcatgcgaat tagtgatcaa
    10141 agccatacac gatatgctta tatcagcaat gagccttcac ttagaccgac ccagggctat
    10201 atcctatacc cagaaggcta tgactttatt caattattag agatttagaa aggaacaaag
    10261 atgtcaacag ttacgatgct tccacttggt agtattgtca ttttaaaggg caatactaag
    10321 aaaatgatga ttattgcgcg tgtgatcgca gctccaatca aaggggaggt ttaccgcttt
    10381 gactatggcg cctgcctgta tccggagggc atgatggggg atagtctgat ttactttaat
    10441 catgacgata tttttaagat tattcaagaa ggctatgctg atgatgacaa tgctttgatg
    10501 ctagagacga tagcgcaggc tttagcaaca acggacattc caaaaggaga tgtttcagcc
    10561 ttaaacgata gaaagactgt tgaggattag cttatggggc aagttgacta caatcatatc
    10621 aatcagcttc aacgtcaggt tgaccagcac agggccagtc tatcaacggc tacagcagag
    10681 atagcgtcaa tagacgaaaa gctagagcgc ttgcgttgtg ccaaggcttc tgttggagcg
    10741 attcaaggag atgttcatca gatcaaggtc tctgtgatgg ctaagaggga tcagcctgat
    10801 tggaaggggg aacgtaagga ccgcttgatg tcgagctggg aggagttctc tcatgactat
    10861 cgccactttc agctggagct agatgcttat tacgatgcca tttgtgatac gataacacgc
    10921 ttggagaatc aaaaatatga gcagcaaggg cttatcggct ggtgtcagag catgattaat
    10981 agcttgggaa atgagattga aaagctattt catattaggg agggctagca tgtttggtgt
    11041 tattcaatta tctgaggttg tttttggagc acatgtgtta agcctgactg ctgctaaggc
    11101 tagcttgtct gatgtcaaag ctagctttcc cagccatcag tcatcaagta aggtgctcga
    11161 tctgtatcag gcagagtttg aagcactctc tcagcttgtt gctgcctatg ctaggctttt
    11221 ggaaaaggat attgccttga ttgccgaggc tggtcaagaa ttggccctaa cagataagca
    11281 gttgggacaa gctataggat ttaggttaca ataggaggag ggtatgggat ataagattca
    11341 ctttgaagcc atcagtgccg cccaacaaag cacccaaacc acgatcagtg cttggggaga
    11401 tgggatgacg agtatccaga ccgcc
//
LOCUS       DARYSY010000057        11354 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYSY010000057 DARYSY010000000
VERSION     DARYSY010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11354
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            184..1602
                     /locus_tag="TVR04_001611"
     CDS             184..1602
                     /locus_tag="TVR04_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1270287.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKETTQPSHLIVYDKYDDKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGVSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKGVLA
                     LVGVGILAMLGLGFWFRPYHKD"
     gene            1857..2126
                     /gene="rpsO"
                     /locus_tag="TVR04_001612"
     CDS             1857..2126
                     /gene="rpsO"
                     /locus_tag="TVR04_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1270288.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            2652..4796
                     /gene="pnp"
                     /locus_tag="TVR04_001613"
     CDS             2652..4796
                     /gene="pnp"
                     /locus_tag="TVR04_001613"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1270289.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGQSTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAVQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIKGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEDKHD"
     gene            4789..5541
                     /locus_tag="TVR04_001614"
     CDS             4789..5541
                     /locus_tag="TVR04_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1270290.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDGVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKAADMIQFMNNYTTILNTLMSDDNSVADTLDRIYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            5553..6089
                     /gene="cysE"
                     /locus_tag="TVR04_001615"
     CDS             5553..6089
                     /gene="cysE"
                     /locus_tag="TVR04_001615"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1270291.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSAQD"
     gene            6211..7554
                     /locus_tag="TVR04_001616"
     CDS             6211..7554
                     /locus_tag="TVR04_001616"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1270292.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKEAGLSPKQLADQFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDVYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKENPLDFALWKSAKTGEIAWASPWSSGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEVAQSEAKTGKAFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAEVNLKYLKNTLQQPTVATAD
                     SSQLAAFVTAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARTNRDFAKADAIRDQLAAQGIKLLDTKDGVRWIRD"
     gene            7547..7954
                     /locus_tag="TVR04_001617"
     CDS             7547..7954
                     /locus_tag="TVR04_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1270293.1"
                     /translation="MTNSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHH
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAVMGYLDMTGQTERLELLIQWCIKQVENRPQS"
     gene            8171..8959
                     /locus_tag="TVR04_001618"
     CDS             8171..8959
                     /locus_tag="TVR04_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270294.1"
                     /translation="MKPMRKVVLVTSAMVLLGSLAFVSAVAAQDNQPTIAAQAQVAAE
                     ASVSARMRSEQSVIEANIATSQPVSQSTEATILLKDAKGNTINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKSFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSETASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     DKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            9008..9754
                     /gene="rlmB"
                     /locus_tag="TVR04_001619"
     CDS             9008..9754
                     /gene="rlmB"
                     /locus_tag="TVR04_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1270295.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLRGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFVLRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIILKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            9755..10273
                     /locus_tag="TVR04_001620"
     CDS             9755..10273
                     /locus_tag="TVR04_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1270296.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            10457..11317
                     /locus_tag="TVR04_001621"
     CDS             10457..11317
                     /locus_tag="TVR04_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1270297.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDTSGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
BASE COUNT         3373 a         2171 c         2727 g         3083 t
ORIGIN      
        1 aattaataga taaaaaatga taatcgttcg tcaataaatc aaatatctaa tctaaaaaaa
       61 ttatattgtt ctgattattc gggaatcaaa gcaatagcgc ttgtcgaaaa actaatgttc
      121 tcttaatatc aggtagccat gccaagggtt ttgtgttaaa gtataggacg ttcaaaaaat
      181 gaaatggaga gactaatgag aacacaattg aaaaaattgc tggcaggaac agcagcaggt
      241 accctgctgc tgtttaacct gacctgcgga atgattaatg cttttgcaga gcaatattac
      301 gggtggagtg acgggagtag cagctatccg agtgctttgt atgttacacc ggtaggagat
      361 actacgaaaa agatagctat tcctgtttat tgctttgact ataagtttca ggagccactt
      421 gcttggaaag aaacaactca accgtcacac ttgattgtct atgataagta tgatgacaaa
      481 aatttgatgg cagcactggt tgaaaaacct aatatggtaa gctatgagac taaaactaaa
      541 cttcaaacac ttttaaagac aaagtcaaat ctaataactg caattttaag tagaggttat
      601 ccaaacaaaa gtttttttga taagtataaa aaattaactg atgaagataa aagacgagtg
      661 acacaatgtg ctctttggta tcatactgac aatatttcag aacaagatct tatcacaaaa
      721 catttggatg gggattcagg tgaaaaaagt caagcgctaa aggagttaat aggggttgta
      781 aaaaatactt ctaatgagtt aggagaggga ttaaccttct atactcgtta taatgataga
      841 tatggtccta aatatcaaaa cctaataggc tcaattattg ttcccgaaga gcctcagaat
      901 gatcttgaaa ttggtggtgg aaatgttatt gatttaaact accaatctgg accaatggta
      961 gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg acactaaaaa gcctgatgtg
     1021 attattggtg gtcagggaag cgtcactgag actactgagg atactcaaaa gggtgtgagt
     1081 ggcagtactg agactcagcc agaggttgag gatactaagc agccacaatc agatattatc
     1141 ctaggcggac aaggcaatgt gattgacaca actgaaaata cccaagaggg catgggtggc
     1201 caatcaggtg atactacaga gactgaggat accaagcagc cacaatcaga cattatccta
     1261 ggtggacagg gcaatgtaat tgacaccact gaaaatactc aagagggtat gagtggttcc
     1321 aacaatggtc aaacatttga ggaggacaca cgtcctaagc tggaattcca ttttgataat
     1381 gaagtgccta acgatgatga cgctcctaaa ccagagcagc cagaacagcc agagcaacca
     1441 aggaagccac agcaggagca gcaaagccta ccacgtccaa tagagggcaa ccagtcattg
     1501 ccaaaaacac atgaggcaaa aggtgtactg gctctagtag gagtaggaat ccttgctatg
     1561 ctaggactag gcttctggtt tagaccttat cacaaagact aagttaaagc ttggtgtcga
     1621 ctgagctgag atgatgtcgt ctaactaaaa gcttatgaag attggagagg ttagtatcag
     1681 tagcttctcc gattttttta ctagctgctg cttttgcatg tagcatttat gagaataata
     1741 gttgaccagt tctggctatt ttgctagaat agagaggtcg caagacagac taactttttc
     1801 ttggttttag gagtgccaac cctaagactc ggattaagca aaaaaggaga attattatgg
     1861 caatctcaaa agagaaaaaa aacgaaatca ttgcacagta tgcacgtcat gaaggtgaca
     1921 caggttcagt tgaggttcag gtagctgttc ttacttggga aatcaaccac ttgaacaacc
     1981 acattaaaga gcacaaaaaa gaccacgcaa cttatcgtgg gttgatgaaa aaaatcggac
     2041 atcgtcgtaa cctattagca tacctacgtc gtacagatgt taaccgttac cgcgagttaa
     2101 tccaatcact tggacttcgt cgttaataag attctaagga cgttaagcag tcctagtagg
     2161 ataggacact gtcaatgtgt agctgcataa ggcagtttgt cctgcttgct atggcttttg
     2221 caaaggttcg ataaggctct tctaatttag aagggctttt tttgaatcct tggctttctt
     2281 gtctttcaga gatactgagg attcattttt tatactggtg ttttgctatt gttataagct
     2341 gaaggtgtct agggctttct agcctagaga agccttggcg tggctgaagg tatgatattg
     2401 cttgcctctc ttgtgccaaa caaaagcagg tctggtacag taattgctta gtggcagtgt
     2461 caaaaagcag tgatggtaat agttacctag cttcttttct cttaaaaatc ctgtcaacag
     2521 ctctgctatt tccctaaaaa tatgatagaa tataagggat actgggtttt atgcaaagac
     2581 gggtccatga gctatcacgc gctggtcttt gtagaaaaca gagtatcaca tttaatgatt
     2641 aggagttttt catgtcaaaa caaacattta caacaacctt tgcaggcaaa ccacttgttg
     2701 ttgaggtcgg tcaagtggct aagcaagcaa atggtgccac tgtcgttcgt tatgggcagt
     2761 ctacagtgct aaccgctgct gtcatgtcta agaagatgtc aacaggagac tttttcccac
     2821 ttcaagtcaa ttacgaagaa aagatgtatg cagcaggtaa gtttcctggt ggctggatga
     2881 agcgtgaggg gcgtccttcg acagatgcaa ccttaaccgc tcgcttgatt gaccgcccta
     2941 tccgtcctat gtttgctgag ggctttcgta atgaggtcca ggtgattaat actgtcctgt
     3001 cttatgacga agatgctagt gcccctatgg ctgctatgct tggtagctca ttagccctat
     3061 cgatttcaga tattcctttt aatgggccta ttgctggtgt tcaggtggcc tatgttgagg
     3121 gtgaatttat catcaatcct gataaggccc agcaggaggc ttccctacta gagttaaccg
     3181 tagcaggaac aaaagatgcg atcaatatgg ttgagtctgg tgccaaggaa ttgccagagg
     3241 ctattatgct agaagcgctt ttggttggtc ataaggctat acaggagttg attgcttttc
     3301 aagaagagat tgttgcagcg gtgggcaagg aaaaggctga ggtagagcta ttacaggttg
     3361 ctgctgattt gcaggctgag atcatagaga cttacaatgc tgatttgcag caggctgttc
     3421 aggttgagga gaaaaaagca cgtgaggccg caaccgaggc tgtcaaggag cgtgtcatag
     3481 ctgcatacga ggagcgttat gcagcagacg aagagcatga ccgtatcatg cgtgatgtgg
     3541 ctgaaatttt ggagcaaatg gagcatgctg aggttcgtcg cctcatcact gaggataagg
     3601 ttcgtcctga tggccgtcgt gttgatgaga tccgcccact tgctgctgag attgatttct
     3661 tgccaagagt acatggctca ggcctcttta cgcgcggtca aactcaagct ttgtccgtct
     3721 tgaccctagc cccaatggga gacactcaaa tcattgatgg gcttgagcct gagtacaaaa
     3781 aacgtttcct gcaccactat aatttccctc aatattctgt tggtgagaca ggtcgctatg
     3841 gggcagcagg acgtcgtgaa attgggcatg gtgccttagg tgagcgtgct cttgctcagg
     3901 tccttccaag ccttgaggaa tttccatatg ctattcgtct agtggctgag gtattggaat
     3961 caaacggttc ttcctcgcag gcctctatct gtgcagggac gcttgctttg atggctggtg
     4021 gtgtgccgat caaggcaccg gttgcgggta ttgctatggg acttatctct gatgggacaa
     4081 actacactgt cctaacggat attcagggct tagaggacca ttttggcgat atggatttta
     4141 aggttgcggg gacacgccaa gggattacag cccttcagat ggatattaaa attaaaggta
     4201 tcacacctca aatcctagaa gaagccttgg cgcaggctaa aaaggctcgc tttgaaattc
     4261 ttgacttgat tgaggcaacc attgctgagc ctcgtccaga attggcacca acagcaccga
     4321 agattgatac catcaagatt gatgttgata agatcaaggt ggttattggt aagggtggcg
     4381 aaaccattga caaaattatc gctgaaacag gtgtcaagat tgacattgat gaggaaggaa
     4441 atgtttcaat ctactcaagt gatcaggacg ctatcaatcg tgctaaggaa atcattgcta
     4501 gcctagtacg tgaggctaag gtaggagagg tctaccatgc taaggttgtc cgtattgaaa
     4561 aatttggtgc ctttgttaac ctctttgaca agacagatgc gctggtgcat atctctgaaa
     4621 ttgcttggag ccgcactacc aatgtctcag atgttcttga aatcggtgaa gaggttgacg
     4681 ttaaggttat taaggttgat gataagggac gcattgacgc atcaatgaag gccttggtgc
     4741 cacgcccgcc aaagccagaa aaatcagaag caaaaaaaga agacaaacat gactaacaca
     4801 aatgaactag atattcgttt aagagccttt atcaatgccc cagacaattt tttagatggc
     4861 gtggccttgg ttaatgcttt tcatcagtat ccggtatggg cagcaaaaaa gccctatgcc
     4921 attgagattg aaggggtaag gatttttcct gtattcacag ataaggacga catggcgacc
     4981 tttaaagagg agcaaaagag tgcacaagct cagtactggg tagagcgctc tgctcttact
     5041 gtcttggagg aggctgttca tgcaggtgct gctgggctag gctttaatct caagaaaaag
     5101 ggagattttg gaaattctac agtattcaag gctgctgata tgattcagtt tatgaacaat
     5161 tacacaacga ttttgaatac cttgatgagt gatgacaata gcgtagcaga tactctggat
     5221 aggatttatc tggtgccggc ctttgtttac cctaaggaag aggagcatta ctatgacagg
     5281 ctttttccaa ccatgtcaac tccagagggg aagcgctatg ttcctgcctt ttcaaatctt
     5341 cagagcttcg ctaaatggta taatcaagag gagtttggcg gcctttttag gaaatcaggc
     5401 ggtgttatct taacatggaa gatagcagac atttatcagc caagaaatgg caataatgac
     5461 atagacgaga cctttggggt tgctattgac ccctttgatg atcagcagat tcttgttgat
     5521 tggtctgata ttgacacata aaaggagttt gaatgggctg gtggaaggac aatattgata
     5581 ttgtaaagca actagatcct gctgcacgta gcaccctaga ggttatccta acctaccctg
     5641 gattaaaggc cttggcagcg cacaggctgt cacatttttt gtggcagcat ggctttaagc
     5701 tgttggctcg aatgcatagc cagttttggc gattttggac acagattgaa atccacccag
     5761 gagctaggat tgcttcaggt gttttcattg accatggggc tggcttggtg attggtgaga
     5821 cggccattgt tgaaaaagga gccatgcttt atcatggagt gacgcttggt ggaactggaa
     5881 aagatcgagg aaagcggcac cctactgttc gtgagggggc actaatttct gcccatgctc
     5941 aaattatcgg tcctgtcgag attgggaaat cggctaaggt tggagctgca gctgttgtgt
     6001 tgactgatgt acctgctggc gtgacggtcg ttggcattcc agcccaaatt gttcgagtgc
     6061 atgagaaaaa gccttcagcg caggattaaa agccctctct aggtggagac agccagtcaa
     6121 aaaacgggag agttagagcc ctatgcttac ctcagttgct gacagcttgc gcagtctagg
     6181 agaaaaggat aaaaacaaaa gggaaaagtg atgataaaaa tctatgatac catgaccaga
     6241 agtctgcgag agtttgtacc aataactgat aaggtggtca atatgtatgt ctgcgggcca
     6301 acggtttaca attatattca cattggcaat gcgcgttcgg ctgtggcctt tgatacgatt
     6361 cgtcgctact ttgaatacgc aggctataca gtcaattaca tttcaaattt tacagacgta
     6421 gacgataaga ttatcaaagc agccaaggaa gcaggcctgt caccaaagca gttggcagat
     6481 caatttatcg ctgcctttat ggaggatacc aaggcactcg gtgtgaagcc ggccaccaaa
     6541 aatccacgcg tcatggacta tatggacgag atcattgcct ttatcgctgc tttaatcaaa
     6601 aaaggctatg cctatgagtc ggcaggtgat gtttatttcc gcgtggcaaa ggcatcaaat
     6661 tatgccagac tggctaataa aacgattgct gatttggagg ctggtgccag tggtcgtaca
     6721 gataccgaaa ctgctctcaa ggaaaatccc ttggactttg ccttgtggaa atcggctaag
     6781 acaggtgaga ttgcttgggc aagtccttgg agctcaggtc gtcctggctg gcatattgag
     6841 tgctctgtaa tggcaaccga gcttttggga gataccattg atattcatgg tggtggagca
     6901 gacctggaat tcccacacca taccaacgag gtcgctcagt cagaagcaaa aactggcaaa
     6961 gcctttgcca attattggat gcacaatggc tttgttaatg ttgacaacga aaaaatgtct
     7021 aagtcactgg gcaactttgt gactgttcat gatctgttaa agacggtaga tgggcaaaca
     7081 ctacgctttt tcttggctac tcagcactac cgtaagccaa tcaattttac agaaaaggct
     7141 attcatgatg cagaggttaa cctcaagtat ctgaaaaata cccttcagca gccaaccgta
     7201 gccacagctg atagcagtca gcttgctgcc tttgttacag cctttaaagc agctatgaat
     7261 gatgatttta atacagcaaa tgggatcaca gtcttatttg acatggcaaa atggattaat
     7321 tcaggtgcct actcagaagc tgtcaaatca gcatttgaag agatgctggc ggtttttggc
     7381 attgtctttg aagcagaaag cctagacaca gagattgagc agctgattgc tgagcgtcag
     7441 gaggcacgca ccaatcgaga ttttgcaaag gcagatgcta ttcgggacca gttggcagct
     7501 caggggatca agctgttgga tacaaaagat ggtgtgaggt ggatacgtga ctaattcagt
     7561 tgatgtcaat ttgattaatg gcattgccct tgcctttgtt ggtgatgctg tttattctta
     7621 ttatattcgt cgtcatctga ttttccaagg ccagaccaag ccaaataagc ttcaccacct
     7681 tgcaacaaaa tatgtttctg caaaggcaca ggcctctttg attcaggcca tgctagaagc
     7741 acagctattg accgaaaaag aaaaagacat ctacaaacga ggccgcaata ccaacagcca
     7801 taccaaggca aaaaatgctg atgtagtaac ctatcgtatg tcaacaggct ttgaggctgt
     7861 tatgggctac cttgatatga caggtcagac agaacggcta gaactgttga tccagtggtg
     7921 tatcaagcag gtggagaaca gacctcaatc ataatgatga ataatctaaa acactctcta
     7981 tgtcgctagc gatctgccat cgcttaaagc tatgagagtg tttttatgtt gcgtttaaat
     8041 tatatgtcac actattgata tatttgaatc aaaaaataaa tatttgtaac aaaaatgaaa
     8101 taaaataatt gaaaaatatc gcgaatagat tataatgaaa gagtcataac aaaatgatag
     8161 gagaatgtct atgaaaccaa tgagaaaagt agtcttagtt acttcagcaa tggtgctgtt
     8221 aggctcactt gcctttgtat cagcagtagc agcgcaggac aatcaaccaa ccatagcagc
     8281 tcaagcacag gtagcagctg aggccagtgt cagtgctcgt atgcgttcag aacagtccgt
     8341 tattgaagct aacattgcca caagtcagcc agttagccaa agcactgagg ctactatttt
     8401 actaaaggat gccaaaggca acacgattaa tagcacagct tataccatgc aggctggtca
     8461 aagccggttt tcagtatggt ttgaccttac gaacctaaag gtcagtgatt acagtatatc
     8521 agtaagtgtt cctgataaag aaaagtcctt tagtggtagc tcagcaccta ttcattttga
     8581 tggaaagcca accaaaaata ccccagagac agaacagaaa aacagcaatc cagtaccagc
     8641 taataaccag cctaaacccg ctgctagcgg cagggtgaca agcactgagc aaccccaaaa
     8701 tgtgcctagc gagactgcca gcgccaatca tatgacaaga accaatcatc gatctgataa
     8761 ggtcctaaag gcaagctcaa gcaacacacc atcagctgcc aaatcaatag actctgctga
     8821 gaaagacaag ggcatgcttt ctgatagcac agcccaagat aaagagcaaa aaggctttcc
     8881 ttggctgcta tcatctctaa ttgcaattac agcagctgct ttacttgctc ttgtcatcaa
     8941 agctgttcac aggaaataaa aagagcagca agagctattt tattgctttc gtggtataat
     9001 aaaaaccatg aaagctaaag aaatcaatga aaccaaggat attgtttatg gcgtccatgc
     9061 cgttaccgaa agcctactag ccaatactgg aaataagctt tacattcaag aggatctgcg
     9121 tggtaagcat gttgatcaca tcaaggattt agccactagt aagaaggtgt ctatctcttg
     9181 gacaaaaaag aaggctttga ccgaaatgac agcaggagct gttcatcagg gctttgtgct
     9241 tcgagtgtca gcctttgctt atactgagct agatgagctg ctagagctgg cacagcagga
     9301 ggataatccc ttgctgctca tcctagatgg gctgacagat cctcataatt ttgggtctat
     9361 tttaagaaca gccgacgcaa caggtgtttg tggtgtgatt atccttaagc atcgtgctgt
     9421 tggtgtgaca ccagtggttg ctaagacctc aacaggagct gttgagcatg ttccaattgc
     9481 tcgcgtgaca aatcttagcc aagcattgga tcagctaaaa gcaaatggct tttgggtctt
     9541 cgggacagat gtaactggta caccatcata caagtggaat acctcaggca agctggcttt
     9601 gattattggc aatgagggca agggcatttc agctaacatc aaaaaacagg tagatgaaat
     9661 gattaccatt cctatgatgg gtcatgttca gagcttaaat gctagcgttg cagctgctat
     9721 tttgatgtat gaagtattta gaaataaatt atagatgaaa aaaagactat tgctggttga
     9781 tggctataac atgattgcct tttgggaatc aactcgtcag ttttttaaga caaaccaatt
     9841 ggatcaagct agaaggatct tgctaaataa gctgaacaac tatgcgcatt ttgatgatag
     9901 tgacattatt tgcgtatttg atgctcagta tgttccagga cttagacagc gttatgacca
     9961 atataggatc tctgttatct ttactgagga ggaagaaaca gctgatagct atattgagcg
    10021 gactgctgct gagctcaaca ccgctctaac catggtagag gtggctacta gtgatctgaa
    10081 tgaacagtgg acgatctttt cccaaggcgc cttgcgtgtc actgctaaag agcttgagca
    10141 gcgtgttaat gctgttaagt cggatttaga taagctgtca caggatattg atcttaaaaa
    10201 gcctagactg ggtccctttg atcaagggca gcttaatcag ctcaaggact ttatgaatcg
    10261 attagatgat taataagctt atcttgctag cttttctagg tatgattctc caggctgcta
    10321 gagcagctca tacgatctaa cggtgatcat ttctgaggca gctggttctt attgctttct
    10381 tagctgatat ttttttgtta tactatgaga aaatcatttg attattaaac gataatgacg
    10441 ttacttggga gttcagatga catttgtatt gatgacagat tcaacagcgg atttagattc
    10501 tttttgggca aaggagcata acatcgatat agtaggccta actgttgaat gtgatggcaa
    10561 ggtttacaag acggttggtc cagatagatt aacgagtgat gctttgctag ctatgatgaa
    10621 aagtgggagc cagcccaaaa caagccagat aaatgttggt cagtttgaag agatttttcg
    10681 acattacgca gctgataacc aagctctttt atatatcgcc ttttcttcag tcctatcagg
    10741 tacctatcaa agtgctgtca tggcacgtga gctggttttg gaggactatc cggacgctgt
    10801 aattgagatt gttgatagct tggctgcagc aggaggagag ggctatttga ccatgctagc
    10861 ctcggaggcg cgtgataacg gaaaaagctt attagaaacc aaagcgataa tagaaggtat
    10921 tttgcctcgc ttgcgtacct attttttagt agatgacctt tttcatcttg tgcgaggagg
    10981 acgcttgtca aaaggctctg cttttatagg cagcttagtg aatattaagc ctctcttatg
    11041 gattgatacc agcggaaaat tagttcctat tgccaagatt cgtggccgta aaaaggccat
    11101 taaggaaatt gctgatagag ccacaaaaga tattgctgat tcaactgttg ttgtgtccta
    11161 tactagtgat cagactgggg cagatgacct gcgagaacag ctattagcac atgaaggtat
    11221 cagtgatgtc tttatgctgc cacttgggcc ggtgattgct gctcatacgg gtccagatac
    11281 cttagcggtt tttgtcattg gcaaggaaaa aagataaaaa gaaaaggatt gaaaggcttg
    11341 aactgctccc tgtc
//
LOCUS       DARYSY010000058        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYSY010000058 DARYSY010000000
VERSION     DARYSY010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            331..849
                     /gene="rimM"
                     /locus_tag="TVR04_001622"
     CDS             331..849
                     /gene="rimM"
                     /locus_tag="TVR04_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1270298.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGCSLKIAKEHQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLGVDIEKGRV
                     DVEIMEGLDDED"
     gene            839..1570
                     /gene="trmD"
                     /locus_tag="TVR04_001623"
     CDS             839..1570
                     /gene="trmD"
                     /locus_tag="TVR04_001623"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1270299.1"
                     /translation="MRIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSELSEGEN"
     gene            1570..2562
                     /locus_tag="TVR04_001624"
     CDS             1570..2562
                     /locus_tag="TVR04_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1270300.1"
                     /translation="MQERIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     TVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKVDGDFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFSGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKASHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEVMTLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTSLVD"
     gene            2694..3752
                     /locus_tag="TVR04_001625"
     CDS             2694..3752
                     /locus_tag="TVR04_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1270301.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            3764..4687
                     /locus_tag="TVR04_001626"
     CDS             3764..4687
                     /locus_tag="TVR04_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1270302.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQTIKENGL
                     KISGDVEEIVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTASLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKEDILKIK"
     gene            5123..5836
                     /locus_tag="TVR04_001627"
     CDS             5123..5836
                     /locus_tag="TVR04_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1270303.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKERIAQKAAELIFDNDVIFIDAGTTTEFLLPFLQ
                     SKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIKQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            5833..6744
                     /gene="pfkB"
                     /locus_tag="TVR04_001628"
     CDS             5833..6744
                     /gene="pfkB"
                     /locus_tag="TVR04_001628"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1270304.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESIHTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDSLAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEAAYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            6741..8687
                     /locus_tag="TVR04_001629"
     CDS             6741..8687
                     /locus_tag="TVR04_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1270305.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGTAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            9270..9869
                     /locus_tag="TVR04_001630"
     CDS             9270..9869
                     /locus_tag="TVR04_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1270306.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSFWTLASAKDHLKPHA
                     NSSTMLFVSRISHSAQVVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYQIDAPFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            10429..10626
                     /locus_tag="TVR04_001631"
     CDS             10429..10626
                     /locus_tag="TVR04_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270307.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
     gene            10661..10996
                     /locus_tag="TVR04_001632"
                     /pseudo
     CDS             10661..10996
                     /locus_tag="TVR04_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3146 a         1907 c         2613 g         3330 t
ORIGIN      
        1 ttttttgatg cttgtcagcg aggcgcaagg ctgttgttta gcagattttt cattcacttg
       61 actgagcttg ggcaaggcaa gtcatgatga tttgttaatt atagggggat caggattctt
      121 tagtatcaag ggctttgctt gctaggctta gctactatag ctgggagatt aattttttga
      181 aagagaagtg caaaataagg cagaacatgt tacaataagg ggagcttcaa agataggcta
      241 gagcgcttag gatgatgata tttatgtcgt gttgtcatga aaaaatagag gtctatcaag
      301 ctatagagtc taagatgatt aggagtaagg atggaatatt ttaacgttgg gaagattgtc
      361 aatactcaag gcttgcaagg agagatgcga gtgctgtctg tgagtgactt tactgaggaa
      421 cgatttcaaa aaggagctag attagctctg tttgacgaca aggatcgttt tgtgcaggag
      481 gttgagattg ctagccatcg caagcacaag cagtttgaca ttattaagtt taagggaatg
      541 taccacatca atgctattga gcagtttaag ggctgcagtc ttaagattgc taaagagcac
      601 cagggtaagc tagctgaggg agaattttac tatcaccaga ttattggtct ggaggtgtat
      661 gaaaaggacc agctagtagg agagattaag gaaattttac agcctggtgc aaatgatgtt
      721 tgggtggtca aacggcaaag caagcgtgat ttgctgttgc cttatatccc atcggttgtt
      781 cttggtgttg atattgaaaa gggtcgggta gacgttgaga ttatggaagg cttagatgat
      841 gaggattgat attttaaccc tttttccaga aatgtttgct cccttagagc attctattgt
      901 tggaaaggct aaggaaaagg ggcttttaga tattcattac cacaattttc gtgaccatgc
      961 ggagaaagct aggcatgttg atgatgagcc atatggtggt gggcagggca tgctgctgag
     1021 agcgcagcct atttttgata ccatggatag cattcaggct acaaagcctc gagtgatttt
     1081 actggatcct gctggaaaac cctttcatca gtcttatgct gaagaattag ctcttgagga
     1141 agagttaatt tttatttgtg ggcattacga aggctatgac gaacgcatta agacgcttgt
     1201 taccgatgaa atatctctgg gagattttgt cttaactggt ggtgagctgg ctgctatgac
     1261 aatgattgat gcaacagtga gattgattcc taatgtgctt ggaaagcaag ccagtcatca
     1321 ggaggattcc ttctcatctg ggctcttgga gtacccgcag tatacaaggc catatgatta
     1381 tcgtggcatg aaggtgcctg atgtcctaat gagcggccat catgagcata ttcgtctctg
     1441 gcgtatggag caaagcctaa agaagaccta tttgagaagg ccagatttat tagagactta
     1501 tgatttttct gatgaggaaa aaaggatttt tgataaaatc aaatcggagc taagtgaagg
     1561 agagaactag tgcaagaaag aatatatgat atcaccatca ttggcggagg tccggtaggc
     1621 ttgtttgcag ccttttacgc aggcctgcgt ggtatgactg ttaagattat tgaaagcctg
     1681 tcagagctag gaggacagcc gactgttctt tatcctgaaa aggttatcta tgatattcca
     1741 gcctatccag ccctgactgg agcagaacta acacaaaagc ttattgagca gctaagcaga
     1801 tttgacgatc gtatagcggt ttgtttgaaa gaagaggtcc tgtcctttga gaaggttgat
     1861 ggagattttg ttattcaaac aagcaaggcc agacattatt ctaaggccat tattgttgct
     1921 tgtggcaatg gagcctttgc acccagaacc ttgggactag acaatgagca gttattcgct
     1981 gatcataatc tcttttataa tgttcacagc ttgaatcagt tttctggtaa gagggttgtg
     2041 atctgtggtg gtggagattc tgctgtggat tgggctttag ccctagatgg tctcgctaag
     2101 agtgttactc ttgtgcaccg gcgagatgcc tttagggctc atgagcatag cgtagaattg
     2161 ctaaaggcct ctcatgttac aactctgact ccttttgttc ctcttgctct tgagggggaa
     2221 aatggctttg tcaacaaaat gactattcaa aaggtaaagt cagaagaagt gatgacgctt
     2281 gagctagaca gcctgattgt tagctttggc ttttctacat ctaataaaaa cctaaagcat
     2341 tggaatctag attataagcg ctcaagtctt cttgtctctc ccctctttca aacaagtcag
     2401 gaagggattt ttgcgatcgg tgacgcagca gcttatgaag gcagggttga tttgattgcc
     2461 actggctttg gtgaggcacc gattgctgtc aaccaagcga ttaagtatat ttatcctgat
     2521 agagataata gacctgttca ctcaacttct ttagttgatt aatggtggat tataattcgt
     2581 ggaatattct ggaaaaataa acattaatta aaatggttgt gacaaaatgc tctttttatg
     2641 ttagaatact ttcgtgatgt ttttcacact ataatattaa gagaggtcat gaaatgacaa
     2701 caacaaataa agagaccttt agttcgttta tgaataaggt cttagctggt acagcaattg
     2761 cgattgtagt tgcacttatt ccgaatgcta ttttagcgac gtttttaaag ccgcttttgc
     2821 caaatactgt agcagctgaa tttttacata tcgtccaggt tttccaattc tttacgccag
     2881 ttatggctgg ttttttgatt ggacagcagt tcaaatttaa cccaatgcag cagctggctg
     2941 tcggcggggc agcttatatc ggttctggag cttgggctta tacagaggtt atccaaaaag
     3001 gtgttgccac tgggaccttc cagctaaagg gcattggtga tctgattaat atgatgatca
     3061 cagctgcgct tgccgtttta gcagtgaagt ggtttggtga taaatttggg tctctaacca
     3121 ttattttgtt gccaattatt attggaacag gtgtgggtta cattggctgg aagctgcttc
     3181 cttacgtttc ttatgtgacg accctgattg gccaaggcat taattcattt acaacgcttc
     3241 agccaattct gatgtctatt ttgattgcca ttgcctttgc tcttttgatt gtgagtccga
     3301 tctcaacggt tgcgattggt ttagctatcg gcttaaatgg tatggcagct ggtgcggcct
     3361 caatgggtat tgcttcaaca actgctgttc ttgtgtgggc aacgttaaag gttaacaaat
     3421 caggtgttcc aattgccatt gcccttggcg ctatgaaaat gatgatgcca aacttcttaa
     3481 aacacccagt tatggctatt ccaatgatga tgacagctat tgttagctct ttaaccgttc
     3541 caatgtttaa tctgattgga acaccagcct catctggctt tggtcttgtt ggtgcagttg
     3601 gtcctattgc ttcacttgca ggtggcagca atattgtgat cattatcatt gcttggttgg
     3661 tcattccatt tggagttgct tttgtggcac ataagctttg taaggatatt ttaaagcttt
     3721 ataaagaaga tatttttgta tttgaaggat aagaggaaaa agcatgttag tttatattgc
     3781 aggctcagga gctatgggct gtcgatttgg ttaccaaatt tcaaaaacaa acaatgacgt
     3841 tattttactg gataattggg aagcacatct tcaaacgatc aaagagaatg gcttgaagat
     3901 ttcaggcgat gtagaggaaa tcgtaaagct tcctatcatg aagccgacag aggctactaa
     3961 ggaagctgac cttatcattt tgtttaccaa agccatgcag ctgccacaaa tgctgactga
     4021 tattaaaggt attattggcc ctgaaaccaa ggtactttgc ctattaaatg gtcttggaca
     4081 cgaagatgtg attcgtcact atattccaga gcataatatt ttaatgggtg ttaccgtttg
     4141 gacagcgagt cttgagggac ctggtcaggt acacttacaa ggagttggtg cgcttaatct
     4201 acaaagcatg gatccagcaa accaagaggc aggacatcag attgctgact tgctaaatga
     4261 cgctcaattg aatgcaactt atgatgataa tgttgttcca aatatttgga gaaaagcctg
     4321 tgtcaatggt acaatgaact caacctgtgc cctacttgat tgcacgattg gtgagttatt
     4381 tgccagcgaa gatggtttaa acatggttaa agaaatcatt catgaatttg tcattgttgg
     4441 tcgtgctgag ggggtggagc ttaatgaaga ggaaatcaca gcctatgtga tggaaacctc
     4501 agtgaaggct gctcatcact acccatcaat gcatcaggat cttgttcaaa atcaccgctt
     4561 gactgaaatt gactttatca acggtgcggt aaataccaag ggtgaaaagc ttggtatcga
     4621 taccccttat tgccgcttga ttacacagct agtccatgcc aaagaggata ttttgaagat
     4681 caaataggtt tagacataag gaatctggga taaaacaatt tctcagtaca ataaaacgag
     4741 aggctcacaa taggtgactc tctcgttttg tcttgttggc tgaaaagact ttgtcctaga
     4801 ctctcattat gaagcaacgg cagtaaatcc gttgcttttt gatttgtaag agactattgt
     4861 gtttcaggct tttgcaacag gtgagagctt ttggaggctc tagttaagaa agaggtcgtt
     4921 aaccattagc ctgcgggtat tgacggggac aatgactgat caattggcag ttattgttaa
     4981 ggcaatagag gtctaagatt gaatttgaat gtttttgaaa gatagtgctt gactttggaa
     5041 taaagtgtag tataatagag ctgtaaacga tttcagacaa aggggtggtt ttatcttaaa
     5101 atcaaaacga aaacagctca ttatggcaaa aatcacagct gaaaattacg ttgcgctaga
     5161 ggatttaatg cagctgttaa gctcgtcaga atcaactgtt cgtagagatt tagatgagct
     5221 ggagcgtgag ggcaagcttc atcgagtgca tggaggtgcc gagctttttc attccttaca
     5281 ggaggaatta tccaatcagg aaaaatctgt caaaaacagt caaatcaaag agaggattgc
     5341 tcaaaaggca gcagagctga tttttgataa cgatgtcatc tttattgatg ctgggacaac
     5401 aaccgaattt ctccttcctt ttttgcaatc aaaaaaagta acagtagtga ctaattctat
     5461 tcaccatgcg actagactgg tagatatggc gatcaagact attattattg gtggctatgt
     5521 caagcagaca acagacgcaa gcattggtca tgttgctttg gagcaaatta agcaaatgaa
     5581 ttttgataag gcttttcttg gtattaatgg cattgatgag gcatttttaa ccactccgga
     5641 tatggaggag gctgttatta aaaaagctgt cattgccaat gctaaaatca cctatgtatt
     5701 agctgatgca acaaagcttg gtcatgtttc ctttgtcaag gtggctccaa ttgatagggt
     5761 tgaaatcatt acagagaaat cttcgacagt aatgctgaag aaaatcaagg aaaaagcgaa
     5821 ggtaattgca ctatgattta cacagtaacc ttaaatcctt ctatagattt tattgtcaga
     5881 atagaccaat tagatattgg ggcggttaac cgcatggtca gtgacgatac atttgcagga
     5941 ggaaagggga tcaatgttag tcgcattcta cagcgattag gcattgataa tacagcgact
     6001 ggctttttag gcggcttcac tgggcgtttt attaaggaaa gtctagctgc tgagagcatc
     6061 catactgact ttgtaacggt tgatcaggat acgcggatca atgttaagat caaatcagca
     6121 gaggagacag agattaatgg ccttggacca gtgatttcaa agcagcaatt ggatcattta
     6181 aaggctatat tagcaaatgt gtcagcagag gacatcgttg tttttgcagg ttcagcacct
     6241 tcaagtctag gcaatgatgt ctataaggac ttgatcccat tagtcagaca agctggggca
     6301 caggtggttt gtgattttga aggacagacc ttgctagatt cattagcgta tcacccattg
     6361 ctcgtaaagc ctaataatca tgagctagaa gctattttta acgtcagctt aaatgggcta
     6421 gatgacgttg aaacatatgc tcgtaaggtc cttgacatgg gagcccaaca tgttatcgtt
     6481 tcgatggctg gtgatggcgc cttgctggtc actcaggaag ccgcttattt tgctaagcct
     6541 attaaagggc aggtgaagaa ttctgttgga gctggtgatt cgatggtggc aggctttaca
     6601 ggtgcctttg tcaaaagcca cagtccacta gaggctctaa aatggggagt ggcctgcgga
     6661 acagcaactg ctttttcaga tgatttagca gcaattgatg atattaaaaa aacatataat
     6721 gaggttgagg tagaggttcg atgaaaatac aggatttatt aagaaaagac atcatgattc
     6781 ttgatttgca ggctatttca aaggaggctg caattgatga aatgattaca gaactagtag
     6841 agcatgggat tgtacatgac tttgatgtgt ttaaaaagag tatcttagct cgcgaggagc
     6901 aaacttcaac aggtcttggc gatggcattg ctatgccgca ttcaaaaaat gttgtcgttg
     6961 accagccagc agtgctcttt gcaaaatcta acaagggcgt tgattacaaa tccttagacg
     7021 gtcagccaac tgatctgttc tttatgattg cagcacctca aggggcaaat gatactcact
     7081 tagcggcctt agccgaatta tcccaatacc tattaaagga tggctttgca gatcaattgc
     7141 gaaaggcaac aagtccagac gaagtgattg ctgtctttga tgcggcttct gatcagaaag
     7201 aggtagcttt tgttcctaca aatgctcagg agtttatcgt tgctgtgaca gcttgtacga
     7261 caggtattgc acatacttat atggcagaag aggccttgaa aaagcaggct gcacagatgg
     7321 gtgtcggcat caaagttgaa accaacggtg cttcaggggt tggcaatcgc ctgacagctg
     7381 atgacatcaa gcaggccaag ggagtcatta tcgctgctga taaggcggtt gagatggatc
     7441 gctttgatgg taagcaattg attgctcgtc ctgtagcaga tggtattaag aaaagcgagg
     7501 aattgatttc actgatttta aacaatgctg gtagtgttta tcatgctaag aatggcactg
     7561 ctgaacaagc aaaagcagct caaaagacaa gcctaggcgg agccttctac aagcacctga
     7621 tgagtggtgt atcacaaatg ctgccatttg taattggtgg tgggatcctg attgctcttg
     7681 ccttcttgct tgacaacatg cttggggtac caaaagatca gctgtctaat ttgggatcct
     7741 accatgaaat agcagctatc tttaaacata ttggtggtgc ggccttttca ttcatgttgc
     7801 cagtgctagc aggctatatt gcttattcta tcgctgaaaa gccaggtctt gtggcaggct
     7861 ttgtggcagg tgccattgct tctagcggtc ttgcttttgg aaaggttcca tttgctgctg
     7921 gcggtgaggc tagcctatca ttagcgggag taccgtctgg atttcttggt gcgcttgtag
     7981 gtggcttcct tgcagggggc gtaattcttg ctcttcgtca agtgcttgca gggcttccac
     8041 gttcgcttga aggggtcaag tcaatccttc tttacccatt acttggtgtt cttgtgacag
     8101 gtcttttgat gctgctgatc aatattccta tggcagctat caatacagca ttgaaccact
     8161 tcttagaaag tctgtcaggc agctctgcag ttcttatggg acttcttgtt ggcggcatga
     8221 tggctgttga tatgggtggc ccagtgaata aggcggctta tgtctttggt acaggaacac
     8281 ttgctgcaac cgttgcaagc ggtgggtcag ttgttatggc tgctgtcatg gcaggtggta
     8341 tggtgcctcc tctagctgtt tttgtggcaa cactcttatt taaggacaaa tttaccaagg
     8401 aagagcgtga atctggcttg accaacattg ttatgggact ttccttcatt acagaaggag
     8461 ctattccgtt tggtgcagca gacccagcac gcgctatccc aagctttatc gctggctctg
     8521 ccctaacagg tgctcttgtt ggtctagcag gtgtcaaatt aatcgcacca catggcggta
     8581 tcttcgttat cgctttgaca agcaatcctt tcttatacct attgtttgtc gctattggag
     8641 cagtggtttc tggtattctc tttggcgcac ttcgtaaaaa agcttagtta ctggctataa
     8701 agccacaagt actagggaaa gcttctgaat tagaatgacc tttccctagt cttaataaaa
     8761 cttcagacgc atgacatcag cctgttttta catgatgtcg tgcgttttgt ttgttgctag
     8821 tagtgatgac tggcgaaaag ctaatattta gagagaatca acctgatcta gaatagctaa
     8881 gtagtgatcc aatagcccta ctaagccaca ccaaacgtgc gaaacagtta ttttcgaatt
     8941 atagtacaaa ttaaagtaga tactatcaac gtttttccca tagtaacatc tatcaaaaat
     9001 aagacatatt cttgaaatag ctaaaccttg aaatcatttg attgtagata tcccatttgt
     9061 tttttgcatc gcttcctttg cgggagcgtg gattgaaata cagcaaagcc ttcttttctt
     9121 gttaaaaact ttttatgcgc ctgttgtggc tgctaggttt ttttagaagt cattaggcct
     9181 gtttttgaga tgagcatgtg gtctggctac attttgcttt taatttttgc tatactaggt
     9241 ttaaaagcaa ggaagtgagg atatttctgt tgaagaggag gaaagctaga agaagccaca
     9301 gggaggctag ctcttggctg gctgctggta ttgttttagg cagcatgttg cttagctttt
     9361 ggaccttagc gtcagctaag gatcacctta agcctcatgc caatagctca accatgctat
     9421 ttgtgagcag gattagtcat tccgcccagg tggttgcgca gcgaaacaag ctttatgcct
     9481 ctgtcatgat ggcacaggcg attttggagt cggcaaatgg tcaatctaag ctaagtcaag
     9541 agccctatta taattttttt ggtatcaaag gaagctataa aggaaaatca gttattttac
     9601 ctaccttgga agatgatggc caaggcaacc tttatcaaat tgacgctcct tttcggtcct
     9661 atggcagctt aacagcctgc tttgaggatt atgctagggt tttgagtgac ccgctttatc
     9721 gccctactca ccgaggcatt catacgagct atcagcaggc caccgctagt ttaacaggta
     9781 catatgccac agatactagc tatggcgaaa agctcaatcg tattataggg gattatcagc
     9841 tgacttattt tgacgctccc atacggtagt tacctccagt atgactgatc taacgagatt
     9901 aacctcatca gaacagcaaa ataattttct aaaatagtta gaaaagctca aacagccctt
     9961 tacgaacgtt taagacgaga tggtgacatg caaggagaaa gcaattctac aaatgatgtg
    10021 aggaaatact atgtgtaagg ctgggcagat ggttaaacgg tccggtttgg tttattgatg
    10081 gattaaatgg atagttaagc tacaaataga caaggcgcat ttttacctat aggtagtagt
    10141 taatagtgag atagcagaaa tgctatcttc ttttgattac tcaaaattaa gataaaaatc
    10201 ccaaaaatga aaagcatagt aaagatatca tcacaaagag aagaaagtgc caccaacaga
    10261 cagaagtata agaggaaaat gcagatatag agaagtggta cgggtaaaaa aagtaagagc
    10321 tagacctata aggaaacgat tttacggaaa gtatacttga cattttctct aaaaaacatt
    10381 atactttatg taaagttagc ttgtcattgt tgcaggaggt cattaaatgt gaaaaataga
    10441 cttgaggaaa tcagaaaaga aaatggaata acacaggaag agttagcatc tattcttgaa
    10501 gtatcaaggc agacaattgg ttctttagaa aacggaaggt ataatccttc cattatttta
    10561 gcttttaaaa ttgctaagta ttttagttta agcattgaag atatctttat atacgaggag
    10621 gaataaaaaa atgaaaagaa atataaaaaa agagatggtt atggcaagaa agttagctat
    10681 tatagttatt gctatcggaa tactttttgc cttgattgct tgcatattat tttttaaaaa
    10741 agatatttta caggtatttc caagaatgga tattgcatgg gtaggctttc tcgttgttgc
    10801 tattcttctg tgtgttagtg gaatatgggt attttcaatt tcaggtaaaa aacaagattg
    10861 gataaatgaa accgatgaaa gagagtcctt aataacagct aaggctaata tggtaggata
    10921 tgtgattcaa acaactttac tgggaatagt ttttttcttc tagtttttat gggctattta
    10981 aacaaagttt ctgggt
//
LOCUS       DARYSY010000059        10771 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYSY010000059 DARYSY010000000
VERSION     DARYSY010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10771
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            43..1332
                     /locus_tag="TVR04_001633"
     CDS             43..1332
                     /locus_tag="TVR04_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1270308.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTSSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHESDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKIFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
     gene            1626..2180
                     /locus_tag="TVR04_001634"
     CDS             1626..2180
                     /locus_tag="TVR04_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1270309.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQQFYDIICHGSHYQFV
                     FPKRMTKDESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            2173..3456
                     /locus_tag="TVR04_001635"
     CDS             2173..3456
                     /locus_tag="TVR04_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1270310.1"
                     /translation="MSKHQEILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            3473..4333
                     /locus_tag="TVR04_001636"
     CDS             3473..4333
                     /locus_tag="TVR04_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1270311.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            4335..5273
                     /locus_tag="TVR04_001637"
     CDS             4335..5273
                     /locus_tag="TVR04_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1270312.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGGVLGIA
                     TLTGLWTMSRSLASLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFIGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMVFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGESPKK"
     gene            5406..6689
                     /gene="aroA"
                     /locus_tag="TVR04_001638"
     CDS             5406..6689
                     /gene="aroA"
                     /locus_tag="TVR04_001638"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1270313.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQALRDLGVSIYEAADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLFGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQL
                     SYQAVDKDIQTASLRVSYSSLKGVEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            6682..7176
                     /locus_tag="TVR04_001639"
     CDS             6682..7176
                     /locus_tag="TVR04_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1270314.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     VLYDRLKKDRLCQRPLFLNHSEAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            7374..8804
                     /locus_tag="TVR04_001640"
     CDS             7374..8804
                     /locus_tag="TVR04_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1270315.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRVLFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            8882..10513
                     /gene="rlmD"
                     /locus_tag="TVR04_001641"
     CDS             8882..10513
                     /gene="rlmD"
                     /locus_tag="TVR04_001641"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1270316.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVEAYLTTSPVRQEKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDVKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKHISVEVELDELDLTSAESKATYAQIKKYILEKFDLKVSTLYIAQIKKKCGIAL
                     REHYNKSKKEKQVIPQCTPEKEEAIMDALRHFKMI"
     gene            10532..>10771
                     /locus_tag="TVR04_001642"
     CDS             10532..>10771
                     /locus_tag="TVR04_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270317.1"
                     /translation="MRWILKIILFPIRLLLSILTTFLTFLLGIGTTILYFLMLMCIVA
                     AIGSFIQKDISLGIEALVLGFLLSPYGIPMVGATVI"
BASE COUNT         3167 a         1962 c         2570 g         3072 t
ORIGIN      
        1 tttttagtgt caaagttttt tgaaaaaagc gagggaggaa aaatggaaaa aaacaaaaag
       61 gtatcctact ttttgcgtca atcagctgtt ggtttagctt cagtgtcagc agcctttctg
      121 gttggaacgt cttcagtggg tgctttagat gcagcaacgg tgttagagcc tacaacagcc
      181 ttcattagag aggctgttag ggaaatcaac cagcttagtg atgactatgc tgacaatcaa
      241 gagcttcagg ctgttcttgc taatgctgga gttgaggcac ttgctgcaga tactgttgat
      301 caggctaaag cagctcttga caaagcaaag gcagctgttg ctggtgttca gcttgatgaa
      361 gcaagacgtg aggcttacag aacaatcaat gccttaagtg atcagcacga aagcgatcaa
      421 aaggttcagc tagctctagt tgctgcagca gctaaggtgg cagatgctgc ttcagttgat
      481 caagtgaatg cagccattaa tgatgctcat acagctattg cggacattac aggagcagcc
      541 ttgttggagg ctaaagaagc tgctatcaat gaactaaagc agtatggcat tagtgattac
      601 tatgtgacct taatcaacaa agccaaaact gttgaaggtg tcaatgcgct taaggcagag
      661 attttatcag ctctaccgag ttctgaggtc attgacgcag cagaactaac accagccttg
      721 actagctata agcttgtcat caagggagca actttttcag gtgaaacagc tactaaggca
      781 gtagacgcag ctgtagctga gcagaccttc agagactatg ctaataaaaa tggtgtagac
      841 ggcgtttggg cttatgatgc tgccacaaag acatttacag tcactgaaca gcctgtagct
      901 gagactattg aggcggcaga attaacacca gctttgacca cctataggct tgttattaag
      961 ggggttacct tctcaggtga aacagctacc aaggcagtag acgcagccac agccgagcag
     1021 accttcaggc aatatgccaa tgacaatggc gttactggtg aatgggctta tgacgctgct
     1081 acaaagatat ttacagtcac tgaggcttta gaggagagtc cagctgatcc agaaaagcca
     1141 tcagcttctc ttccgttgac accgcttaca ccagcaacta agacagcacc agctaagcaa
     1201 aaagataagc aaaaggctaa gactcttcca acgactggtg agaaggctaa tccattcttt
     1261 acagcagcgg ctcttgccat tatggcgagt gcaggtgctt tagcagtgac ttcaaagcgt
     1321 cagcaggact aagcagtgta tttatggaag catgtttagc cttagaagga tgagcttact
     1381 cataggactt ttctatgatg tagtccattt aagcactagc agataagcta gcaagagaag
     1441 atcagacggt cttctctttt ttggttttga ctgttagtaa tagtttaaca gcttagagtc
     1501 tgattgagct gtgatatggc ttgtcaggtt attatgatca tcgtggcaaa actcataaca
     1561 gttatagaat gtttaggtga tatctgctat aataatagta ttacaggcat gttgaagggg
     1621 aggctatgga tatttggaca cagctagcaa ggtttgcttt tgttgagacg caacgactgc
     1681 ttttgagacc ctttcaatat gcagatcatc agcaatttta tgatataatc tgccatggta
     1741 gccattacca gtttgtgttt ccaaagagga tgaccaagga tgagagtgat ttcttaatgg
     1801 tcaatgcttt tatgaaagag cccttgggag tctggttaat agaggataag accagccata
     1861 gtatgcttgg ctctattaga ctagaaaaat atgataagca gcaggcaagt gctgagattg
     1921 gctatttttt agcgcagccc ttttggggac agggcttaat gaccgaggtc ttaaagacgc
     1981 ttaccttttt agcttttcag gagtttggct tgaggcagct gatcattgtg acacatctgg
     2041 aaaacaaggc cagccagagg gttgctgaaa aagccggctt tcgattaaca aagcaattta
     2101 agggcagtga tcggcatagt catcacatac gagattattt agaatatcaa ctaacgatag
     2161 gtgagtatca ttatgagtaa gcatcaagag attttggatt atttagaaag acttgctatt
     2221 ggaaaacgtg tcagtgttcg gagtatttca aatcatttaa aggttagtga tggtactgcc
     2281 tatagagcga tcaaggaggc tgaaaatcgg gggattgttg agaccaagcc gcgtagtggt
     2341 actgtccgca ttgagaaaaa aggacgggtt cgtattgatc gtttgaccta tgccgaaatt
     2401 gcaaggatca gtgattctga ggttttagct ggacatgctg gtttgggaca tgagtttagc
     2461 aagttttcta ttggagcgat gacccagcaa aatattcacc gttatttgat caaaggaggg
     2521 cttttgattg ttggcgatcg tgaaaatatc caactgttag cccttaaaaa tcacaatgct
     2581 atcttagtga cgggtggctt tccggtgtct aagcaggtta ttgaaacagc tgatagccaa
     2641 ggtattccgg ttatggtgac acattacgat acctttacag tggcaacgat gattaaccat
     2701 gccttgtcta atattcgcat taagactgat ttaaaaacag ttgctcaggt tctgattcca
     2761 gttgaagaat acggctgcct ttatgagaca gacactgtcg aggaatttaa tgcactgatt
     2821 aaaaagacag gtcaagtaag gtttccaatt gtagatgcgc ttgatcaggt ggttggtgtg
     2881 gtcagtatgc gtgatgtggt ggatcagcct gctgagacta gacttgagca ggtgatgtct
     2941 ccaaatccta tcactgcaaa gcccaatgct agcctggcta atattagtca aaaaatgatc
     3001 tttgaggatt tgaacatgct cccagtagtt gatgatcatc attttctgct ggggattatt
     3061 accagacgac aggctatgga aaatctgccg aatcaccagc cgggaaatct ttacacctat
     3121 agccagcaaa tgctatcaag ccttgaggag accttggatt attatcaggt catgattgag
     3181 cctaccatga ttgatagtgc tggcaatctg tcaaatggag tggttgctga attcttaaag
     3241 gaaatcagtg tcagagtgtt aacgaaaaaa caccaaaaaa atatcattat cgagcaaatg
     3301 atgatatact ttctacatgc tgtccaaatt gatgatcaat tgaggatata ccctaaaatt
     3361 ataactgaaa atagaagaag cagtacactt gatatggagg tcatggttga tgatcaggtg
     3421 attgctaaag ccattattac aactaagctt aattagagga gaaacaaaaa caatgataac
     3481 attaaaatct gcgcgtgaaa tagaagctat ggatagagca ggagactttc ttgctggaat
     3541 tcacattggc ctcagacaga tcattaagcc tggggttgac atgtgggagg tcgaagaata
     3601 tgtgcgcagg cgctgcaagg aagacaatgt gcttccttta cagatcggtg ttgatggtca
     3661 attgatggat tatccttatg ctacctgctg cgggctaaat gatgaggttg cacatgcttt
     3721 tccgcgccat tatattctac aggaagggga tttgcttaag gtagatatgg tgctaagtga
     3781 gccacttgat aaggctgtcg ttgatgtagc ggccttggat tttgataatg tggcagaaat
     3841 gaagaagtgg acagaatctt atacaggtgg tttggctgat tcctgctggg cttatgctgt
     3901 aggtacaccg tctgatgagg tcaaaaggct gatggacgtg accaaggaag ccatgtatcg
     3961 tgggatcgag caggcagttg tggggaaccg cattggtgac attggtgcag cagtccagca
     4021 atatgctgaa agtcatggct acggtgtggt tcgagacctt gttggtcatg gtgttggacc
     4081 aaccatgcac gaagagccga tggtgcctaa ctatggtaca gcaggaagag gactacgtct
     4141 gaaggagggc atggtgctca ccgtagagcc gatgatcaat actggcacat gggaaattga
     4201 tacagatatg aaaacaggct gggcccataa aacacttgat ggtggcttgt cctgccagta
     4261 tgagcatcaa tttgtgatta caaaggatgg tccagtgatt ttaactagtc agggcgaaga
     4321 aagaacttat tagaatgtca ataaagaaat tcttggacaa ggtcatatca aaatggcaat
     4381 atgagccaat ccaagccttt atgcgccatt ttcagagtgc agagatggat ttgtcagcga
     4441 tcgcagttgc ttattacctt attttgacag cctttccact cattgttatt gcggctaata
     4501 tttttcctta tttaaatatt gatatttcag acttattacg cttaatgaag gagcaattgc
     4561 ctaaggatat ttatcgctct gcctcctcta ttgtggttaa tattttttcc aagccatcag
     4621 gaggtgtctt aggaatagct accttgacag gactttggac aatgtcacga agcctagcct
     4681 ctttacaaaa ggcctttaat aaggcctatg atgcttctga gcatcgtgat tttttgcttg
     4741 gtcatttggt aggcttactg accagcctgc tgattctgtt tttgttgacc tttgccttga
     4801 ttttttcaac cttttctaag gcagcgattc aggtgctgga taggcattat catttaaatg
     4861 acaatatcac aacgctcttt ttattcttga tccagccgat tacgattttg attatattta
     4921 ttggtctgat gctactttat tttttgttac caaatatcaa aatcaagaaa atcaggtata
     4981 tcttaccagg aacatttttt accacctttg tcatgatttt tttgagcaat atggttggta
     5041 attatgtggt gcataatgtg gagcgaatgg tcgatattaa aacctttggt tcggtcatgg
     5101 tttttatcat catgctgtgg tttattttcc tggcaaggat attgattatg ggggcagttt
     5161 ttaatgctac ctatcaagag ctatccatcg gcaaattaga gggacgcagc ggcaatgttg
     5221 tttctctcat caaaaagaca ttaggcaatg atggtgagtc gcccaagaaa tagtggctta
     5281 tcttaaaatg aaaagcaaga ctgtgcttgg tgattagttg atggggtaag gacccttgtc
     5341 cttgcttcat tttcttttat ttgctttgct gagctaatgc tggtgtacta aaaataggag
     5401 taatgatgaa attaaaaaca aaagctaagg cgcttagggg acgtctaaga gtaccaggtg
     5461 acaaatcaat tagccatcgt gcagtcattt ttggtgctat agcagagggg caaacagtga
     5521 ttcatggcct tttaagggga caagatgttt tagccaccat tcaagctctt cgagacctag
     5581 gtgtcagcat ttacgaggca gctgatagct tgatcattga aggaagaggc tttaaaggcc
     5641 taaagccagc tcaaaagcct ctagacatgg gaaattcagg tacttctatg cgcctgcttg
     5701 cagggctatt agcagcacag gatttttcgg tgcagctgtt tggagatgat agcctatcaa
     5761 ggcgtcctat ggatcgtatt accataccat tgtctctaat gggagcagag ctatctggtc
     5821 aaggagaaaa agagcttcca ccactgattg taaaaggctg tcagggcttg cggccaatcc
     5881 attatcaact gcctgtggcg tctgctcagg tcaagtctgc tattttatta gctgctttgc
     5941 agacacaggg agagactgtt atccttgaaa aggaattgac aagaaatcat accgaagaga
     6001 tgattgaaca atttggagga aagctctcag tagctggaaa gcaaatcagt atcaaaggac
     6061 cgcagcgttt gcagggacag accttacaga ttcctggcga tctctctagc gcagcctttt
     6121 ggttagctgc tggtctgatt gttccggggt cagatcttgt gctcgaaaat gtaggaatta
     6181 atcctacgcg gacaggtctt ttggaggtta ttgagaaaat gggcggccag ctttcttatc
     6241 aggctgttga taaggatata cagactgcta gcttaagggt ctcttattct agcttaaaag
     6301 gtgttgagat ttctggtgac ttgattcccc gcttgattga cgaattgcct gtcattgctt
     6361 tgctggcaac tcaggcacag ggaacgactt atatcaggga cgctcaagaa ttacgggtca
     6421 aggaaactga ccgcattcag gctgttactg atgtattagg acagatgggt gctgatattc
     6481 aggcgacaga ggacggtatg gtgattagag gcaaaacacc attacatggt gcagctgtca
     6541 gtacctgtgg agatcataga attggcatga tgacagctat tgcagcccta ctggttgaag
     6601 aaggacaggt caccctagag cgagcagaag ctatcctgac ttcttatcct gactttttta
     6661 aggatttaga gaggttatgg catgactaag ctgttattag gatttatggg agttggtaag
     6721 acgacagttg cagcccaatt agatgagcat tttttggata tggataggct tattgaggct
     6781 aaaataggca tgagcatatc agcatttttt tcctatcgtg gtgaagcagc ctttagaaag
     6841 cttgagtcag ataccttaca ggaagtgctg gcacttgata atgagactat cgtatcaact
     6901 ggtggaggtg ttgtccttag taaggcaaac cgagaattaa tcagaaaaaa tcacaaaaat
     6961 aatatcctct taacagcctc ctttgaggtt ttgtatgaca ggcttaaaaa agataggcta
     7021 tgccaaagac cactgttttt aaatcattct gaagcagaat tctatgctat ttttcagcag
     7081 cgcatggcct tgtatgaggg attggcagac aaagtgatta atgttgagca tagaacacca
     7141 aaggaggttg cagcaatcat tgccaatatg tcgtaactgc tgaggattag acttttggcc
     7201 tcctattcgc agcccagctt ttcttaatga ttaggtatga aaagctaata ataggatgaa
     7261 ataaagttga attctaacga ttttagagga caatctcgtt aatataggtt ataatagaat
     7321 cattagacaa agaatagaag aaattgtatt agaatactaa gagttggaag agcatgacga
     7381 gataccaaaa gggtggtcta agccaccacg aagaattacg atatttttat ttattaagaa
     7441 atttaaatta tttgactgag actgaacgca gagaatttac ctttttaaag tcaaagatgg
     7501 agtcaagggc tatgccttct cgttctcagc gctccttgac tcattatact aggggtgggc
     7561 gtgacgatta tgctcaagct tcacaggata atgctgatgc ttatgatatg agtgatgagc
     7621 aacaggctgg acctaatggc ctgcctcttt atccgagatc agaaagacgt agcaaaaggc
     7681 atcagcaaaa gccaatacta gcccctcagc aggacttcta tgatgaccca gatcaggcga
     7741 tctatgagga gcttgcgcct gaggctatgc ctaaaaaggg tagaaggaaa aaaaagaagg
     7801 gacgtctgag acgttttttc agagtactct ttttcttgtt gctgctgctt gttgcaggga
     7861 tagctttcat gtttttcaag ggaatgatgg acgtgtctac taacaaggcc aattataagc
     7921 cagcagtttc gcaggtcttt catggtcagg atactagcga tggcactaat attttaattc
     7981 taggctcaga ccagaggatt acgcaaggct caacagatgc tcgaacagat acaatcatgg
     8041 tggttaatgt tggcaataag gagaataaaa tcaaaatggt ctccttcatg agagatacct
     8101 tggttaatat tcctggctat agctataata atcaggattc ctatgattta aaattgaacg
     8161 cctcctttaa tttaggagag caggaaaatc atcaaggagc agaatttgtg cgtcagacac
     8221 tcaagcataa ttttgatatt gacattaaat attatgtcat ggttgacttt gaaacctttg
     8281 ctgaggctat tgacacactg tttccagatg gtgttaccat tgatgccaaa tttgctactg
     8341 taaatggcga agcagtcgct gctgttgatg taccagatga tttacgaatg aaagacggag
     8401 tggttcccaa ccaaaccata acggttggtg agcaaaaaat ggatggtcgt accctgctca
     8461 actatgctcg cttccgaaag gacgatgagg gtgattttgg tcggaccgta cgtcagcagc
     8521 aggtgatggc tgctatcatg tctcaaatca aggatccaac caagctcttt acaggctcag
     8581 cagctattgg taagatttat gccctaacct caaccaatgt ctccttccca tttgtcctta
     8641 aaaatggagt gtccgtcttg actaatggca aaaacggtgt ggagcatgtg acgattcctg
     8701 aaaatgggga ttggattgat gaatatgaca tgtatggtgg tcaggctctc tttattgatt
     8761 ttgctaagta tcaaaatcga ttatctaagc tgggattacg ctaagatatg ctataatgaa
     8821 gggtaacgat ggttgctctt cttttttgag tgattagtgt agtaaaagaa aaggaaagta
     8881 aatgttaagt aaaaacgata ttgttcaggt ggaaatttct gatttaagcc atgatggctt
     8941 aggaatcgct aagcatgagg gctttgtttt ctttgttgaa aatgctcttc caggtgaaat
     9001 cattcagatg cgtgtcctaa aggtcaataa aaacagtggc tttggcaagg tagaggccta
     9061 tctaacaacc tcaccggtgc gtcaagaaaa acttgatgtg acctatctgc gcacaggtat
     9121 tgctgatttg gggcacttgc tttatccgca gcagctgctc tttaagcaaa agcaggttca
     9181 ggatagtctc tataagattg cagggattag caatgttgag gtcaaagaaa caattggtat
     9241 ggaatatcct tatgcttatc gaaataaagc ccaggttcct gttcgtcgtg tcaatggtca
     9301 gctagagact ggttttttcc gtaagcattc tcatgagcta gtaccgattt ctgattttta
     9361 cattcaggat aaagaaattg atcgcttgat cgcctttaca cgcgaccttt tgcgccgttt
     9421 tgacgtcaag ccctatgacg aaaaagagca gtcaggcctg attcgtcatc ttgtggttcg
     9481 tcgtgggcat tattcaggag aaatcatgct ggttttagtg acaacacgac ctaaaatctt
     9541 tcgtatcaac cagatgattg acagcctcgt cgcagaattt ccagcgatta cttctatcct
     9601 gcaaaatatc aatgacaagc ctactaatgt tatctttggt aaggcgttta caagactcta
     9661 tggaaaagag acaatcacag atacgatcct gggcaatcaa tactgtattt ctgctcagtc
     9721 cttctatcag gtcaatacaa caatggctga aaagctctat caaacagcta ttgatttttc
     9781 tgaattgacc gctgacgatg tggtgattga tgcctattca ggcattggaa ccatcgggct
     9841 atcctttgct aaagaagtca aagcagtata cggtgtcgaa gtgatcgaag cagcagtgcg
     9901 tgatgccgag aaaaatgcag cgctaaacgg tattaccaat gcctactatg tcgctgacag
     9961 cgctgaaaat gcgatggcaa actggtgtca ggagggcata aagccaacag ttatcatcgt
    10021 agacccccca cgaaagggac taactgagag ctttatcaag gccagtgcag caatgcagcc
    10081 tgacaaaata acctatatat cctgcaaccc cgccaccatg gcgcgtgaca tcaagcgcta
    10141 cgaggaactc ggctataaac tccagaaagt gcagccagta gacttgtttc caatgacaca
    10201 tcacgtcgag acggtggcat tattgtccaa acttaatgtc gataagcata taagtgttga
    10261 agtagagctg gatgaacttg atttgacaag tgctgaaagt aaagcgactt atgcacaaat
    10321 caagaaatat atattggaaa agtttgattt aaaggtttcg acactctata ttgcacagat
    10381 taaaaagaaa tgtggaattg cactgaggga gcattataat aaatcaaaaa aagagaaaca
    10441 ggttattcca caatgcacac cggaaaaaga ggaagctatc atggatgcgt taaggcattt
    10501 taagatgatt taatagaaat ggagggtatt tatgagatgg atattaaaaa taatcttatt
    10561 tccaattaga ttgctgttaa gtatcctcac tacatttctg acattcctgc tcggcatagg
    10621 aacaactatt ctatatttct tgatgctgat gtgtatcgtt gctgcaatag gatcatttat
    10681 acaaaaagat atatcacttg gaattgaggc gttggtatta ggatttttgt taagtccata
    10741 tggaataccc atggtcggag caaccgttat a
//
LOCUS       DARYSY010000060        10762 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYSY010000060 DARYSY010000000
VERSION     DARYSY010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10762
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..716
                     /locus_tag="TVR04_001643"
     CDS             <1..716
                     /locus_tag="TVR04_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HEL1270318.1"
                     /translation="RRRPFKNGEESIFAGIVKCPDCGKSLNLGRNKSKKREKLLTCNT
                     YRRYGKSLCSQHRIYYDTLYEIVLKDIRKNAEIALKDEKEIIKALERSREIDNEEEQK
                     FIMDKIYEDQIRVEDLTKKIERLYDDWLDNKISESNFQKILEKSQKEQDYLNQRIEDN
                     QKLIVKEDLEDINVKKWIELIKKHRDIKKLDKETLNELISKIYVHEKEVVNGEITQTI
                     DIYYNFIGNTDTLQVFYNL"
     gene            720..803
                     /locus_tag="TVR04_001644"
                     /pseudo
     CDS             720..803
                     /locus_tag="TVR04_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            823..1686
                     /locus_tag="TVR04_001645"
     CDS             823..1686
                     /locus_tag="TVR04_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270319.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGEVFAFIKSINDSVIIPIAGLIITAVLCIEIINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSATVSGDQIVAMMDTLKEKG
                     LGELVMILFETSIIKVAIQAISIVIMLVVYGRMFEIYVYSSVSAIPFATMGNKEWGQI
                     GTNYIKGLFALGLQGLFLMVCLGIYAVLVKTIEITDIHTSTMTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            1704..1967
                     /locus_tag="TVR04_001646"
     CDS             1704..1967
                     /locus_tag="TVR04_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1270320.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLYNKVDELEERTEDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEELSKDKEDGR"
     gene            1971..2360
                     /locus_tag="TVR04_001647"
     CDS             1971..2360
                     /locus_tag="TVR04_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1270321.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSANKVRRKQKGTEKSKAGLKAK"
     gene            2272..4698
                     /locus_tag="TVR04_001648"
     CDS             2272..4698
                     /locus_tag="TVR04_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1270322.1"
                     /translation="MNKKRKIQQIKLEENKKALRSQKRDLKQNKGKIKKDSNILDLIF
                     KKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQFA
                     NFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPNKGDGFDDIRLEFREMLKSQIVKGN
                     NGLKKSKYVTFTVEADNFEQATSKLERLEIDILSNLKGMGVRAESLTGEERLKILHDI
                     LNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELSD
                     RMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMDI
                     LPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKHN
                     CKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYYG
                     LNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEGE
                     YGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGSG
                     LTAEEKSVIDRCLPKIYEKYFENPTPDNMPILQDLYDMLKGQEEKVGKKLATEMEIYV
                     SGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATRY
                     YIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDFV
                     LMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILYQ
                     KMTTKPEEVR"
     gene            4702..6825
                     /locus_tag="TVR04_001649"
     CDS             4702..6825
                     /locus_tag="TVR04_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1270323.1"
                     /translation="MDRKLKKDFRERHKASLEREMLRAETSAIPEESKLKHNDDYRGK
                     IVHDKERFQDKVHEKISKVSSDNEQAQGTSKRNTKHRASDKESVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     SKYKRKNYSGSLYTRKKDDVPKENKSEGKRTGKDTLSEKENISLSKDQKKKVKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     DLTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFIGIIILGTFVINFAGTGMTGFMNSTSSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKNVSEVESILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMGEAFGNSDLI
                     SANGGVGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGRIRVT
                     TLDDWIATFCQHHPVGFGFPPNVNR"
     gene            6838..7077
                     /locus_tag="TVR04_001650"
     CDS             6838..7077
                     /locus_tag="TVR04_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1270324.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLMAKVNREKAELKKERTNENQFEKE"
     gene            7052..8602
                     /locus_tag="TVR04_001651"
     CDS             7052..8602
                     /locus_tag="TVR04_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1270325.1"
                     /translation="MKTSLKKNKKFWTAALAVIVSISCILGLWTVVYAQEQRSEVPTK
                     NEAVQTEVEVNVKYIFEDEKVYKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGKDEIIRKVAKTEVKDKQTQTEEEKPKQDTSTQTEDKKTEDKKTQTELSKDDISK
                     MEKEAKELQDKLDKLNGELKDKDKLSDKQKEKIKDLEDEVENLKEKMKKDKGNKDLSE
                     DIKKEIDKLTEKVKELEKKAAETNKAPVTSQSITPISPISGIKTSSGISPQTPQSSVS
                     STGKGSSDSVNSGSATKDTGKTEVKEKEKEVRYPNKLTAKAPANNSQDSSMDSASKSV
                     NTNKGVASAPSKARGSVIENKDNANKDYPIHHGDSSDNKETDMYSADARQFITFQTKN
                     GKTFHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPRQEVVKEEPVKEEVKPEKKD
                     EKSNLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEEIND
                     ADEVEDEE"
     gene            8697..10403
                     /locus_tag="TVR04_001652"
     CDS             8697..10403
                     /locus_tag="TVR04_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1270326.1"
                     /translation="MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLI
                     QMANPDVYDEKYAKWNMADLPIIPKEYKYEVAKSTKKQFAILKKLLNDKEIDTVINAC
                     DAGREGESIFRLVYNQANCKKKMKRLWISSMEDSAIKEGFDNIKDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYKQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELS
                     MNGFTLSTDRIDDEIAAEQLLNLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKY
                     FGYSAKQTLDYAQSLYEKKLITYPRSDSRCLTEDMIVNTVNNILGKNDFDTERIKAVF
                     NSKKVTDHHAIIPTVSSLSEDLSGIPEGEAKVYRLISDKFHASVGYPLIENTTKIVAV
                     FDGFEFTSTGKVIKDEGFSKYLKEYKSKQSEDAVMPDISVGDVLSIENKEIKEKFTQP
                     PKHFTEDTLLKSMEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNL
                     IATHKGISLVTIVADNFKSAETTAKWEMELSDIAQGKSSKEEFLKDIENEIKEAVLTY
                     SK"
     gene            10487..10666
                     /locus_tag="TVR04_001653"
     CDS             10487..10666
                     /locus_tag="TVR04_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1270327.1"
                     /translation="MKDIFMDTAKVMAKGQVTIPKRIRELLNLENGDYVTFVVNKDKV
                     EIQNSNVFIEENIKK"
BASE COUNT         4098 a         1575 c         2386 g         2703 t
ORIGIN      
        1 gcaggagaag accatttaaa aatggagaag aaagcatatt tgcaggcatt gtgaaatgtc
       61 ccgattgtgg aaaatcttta aatcttggaa gaaacaaatc gaaaaaaaga gaaaagttac
      121 tcacttgtaa cacttataga agatacggga agtcgttatg tagtcaacat agaatttatt
      181 acgatactct ttatgagata gtgcttaaag atattaggaa aaatgcagaa atagcattaa
      241 aagatgaaaa agaaattata aaagcacttg aaagatcacg agaaattgat aatgaagaag
      301 aacaaaaatt tattatggat aagatttacg aagatcagat aagagtagaa gacttaacta
      361 aaaagattga aagactatat gatgactggc tagataacaa gataagtgaa agcaacttcc
      421 aaaaaattct tgaaaaatca caaaaagaac aagattattt aaatcaaaga atagaagata
      481 atcaaaaatt gattgttaaa gaagatcttg aagatattaa tgtcaaaaaa tggattgaac
      541 tcataaaaaa acatagggat ataaagaagc tggacaaaga aaccttaaac gaactcatct
      601 caaaaatcta tgttcacgaa aaagaagtag tgaatggaga aatcacccaa acaattgata
      661 tttactacaa tttcatagga aatacagaca cactacaagt attttacaat ctctaattag
      721 gcataaagca gttgatggcg ggaggaggta ttgttcttat cggacttaag ctgattccgc
      781 ttcttgcaaa tgtactcaag taagaagaaa aggagagctt agatgtttgg aatattcgac
      841 aagatagaag aattctttaa agagcttcta ctgggcggta tccaagcaaa cttagagtcc
      901 atgtttcttg acatcaacga caaggttggt gcagttgcaa cagatgtagg aaaaacgcct
      961 atgggatgga acggagaagt atttgccttt atcaaaagca ttaacgattc cgtcattatt
     1021 cccatagcgg gactaattat cacagcagtc ctttgtatcg agattatcaa catggtaatg
     1081 caaaagaaca atatgcacga tacggatacc tttgaatttt tcaagtacat catcaagatg
     1141 tggattgctg tgtggcttgt atctcacgcc tttgagtttt caatggcggt ctttgatgtg
     1201 gcacagcata tggtaaataa ggcggcaggg gtgataaaca cctctgccac cgtttccgga
     1261 gatcagatag tggcgatgat ggatacccta aaagaaaagg gacttgggga acttgtcatg
     1321 attctctttg aaacctccat catcaaggtt gctatacagg caatttccat agtaattatg
     1381 cttgtggttt acggaagaat gtttgagatt tatgtttatt catcggtttc agccattcct
     1441 tttgccacaa tgggaaacaa agaatggggg caaatcggca cgaattacat caagggacta
     1501 tttgcacttg gactacaagg actcttttta atggtttgtc ttggaattta cgcagtatta
     1561 gttaagacga ttgaaataac agatatacac acaagtacca tgacgatact tggatatgcg
     1621 gttttgctgg ggttaatgat gcttaagagc ggaacactgg ccaaaagcgt attaaatgca
     1681 cactaaaaga aaggaaagat agtatgaaca aaagaaaaac agtatttaca gcagtagtaa
     1741 tggtcgcagg cattatggcg gtaattgaca gaatcagact ttataacaaa gtggatgaat
     1801 tggaagaaag aacagaggac atcggtcgct gccacaatga cttttgccta atgcagcaaa
     1861 gatataacaa gaatacagat gaacagcttg caattattca ggatgaaatc ggatctgtat
     1921 atgaacactt tgaggagctg tcaaaggaca aagaagatgg gaggtaagtt atggcgtatg
     1981 taccaattcc caaagatctc aagaaggtca agacaaaggt agcatttaac ttaacgaaaa
     2041 ggcagcttat cggatttacc attgcaggac ttgttggaat accggtctat ttatttatga
     2101 gaaaggtagt accaaatgat atagctgtca tatttctgat tgtgtccaca cttccaatct
     2161 ttttcatcac actttttgaa aaggatggac tgacctttga gaaatatttt aagcatatct
     2221 atcttcataa gttttatcag ccggcaaaga gagtgagaaa ggaggtttac cttgaacaag
     2281 aaaagaaaaa ttcagcaaat aaagttagaa gaaaacaaaa aggcactgag aagtcaaaag
     2341 cgggacttaa agcaaaataa gggaaagatt aaaaaagaca gtaatatact tgaccttatt
     2401 tttaagaaag agccgaaaag atacactgtt gaagatacca ttccctatct tagactctta
     2461 aaaagcggga tatgccagct cgatgaaaag cacttcagta aaagcatagc ctttcaggac
     2521 attaactatc agcttgcttt agatgaagat agggatttga tttttaatca gtttgccaat
     2581 ttcttaaatt cctttgatcc aagcatagcg attgagtttt cctacatcaa tcagcttgga
     2641 cgaaacgaag aaatgaaatc ggcaattcag ataccgaata aaggggacgg atttgacgat
     2701 atacgacttg agtttagaga gatgctaaaa agtcagattg taaaaggaaa taacggactg
     2761 aaaaaatcaa agtatgtaac ctttacagta gaggcagaca attttgaaca ggcaacatca
     2821 aaacttgaaa gactggagat agatatatta tctaatctaa aaggcatggg ggtaagagct
     2881 gaaagtctta ccggagaaga aaggctaaag attcttcacg atatattaaa tccgaataag
     2941 acctttgagt tttcctataa agacctgaag aaaaaggaaa gtaccaaaac atatatcgtg
     3001 cctgatgaat ttaactttat gccaagcagg tatttcaagt ttgggaagtt tatcggagca
     3061 acaagtcatt ttcaaatcct tgcaagtgag ctttcagacc gtatgttatc ggagtttttg
     3121 gatattgatg ataacatcaa tatatctttt catattaagg cgattgacca gtcagaagcc
     3181 atcaagatgg taaaacgaaa aaacaccgat attgacaaga tgcgaattga ggaaaacaag
     3241 aaagctgtaa ggtcaggcta tgacatggac attcttccaa gtgatttaat tacttacgga
     3301 gaagatgtaa aaagtctttt aaaagattta cagacaagag atgagcgtat gtttgttgta
     3361 agtattgtct ttatgaattt tgcaaggaca gtgcagaagc tcgataacac catagctcag
     3421 ataagctcca ttgcaaacaa gcataactgt aaattgaaaa gacttgacca tacgcaggaa
     3481 caaggcttag tgagcgtgct gcctcttggg gtaaacaaga ttgaaataga tagagggcta
     3541 acctcatcat caacagcagt ctttatgcca tttaccacag aggaactttt tatcaactca
     3601 agtaacagtc tgtactatgg actaaatgct ttaagtcata acctgattat ggcggacagg
     3661 aagaaattaa agaacccgaa cggcttaatt ttagggactc ccggaagtgg taaatccttt
     3721 agcgctaaaa gggagatggc aaatgcgatt ttagtaacgg acgatgatgt gattatttgc
     3781 gatccggagg gagagtatgg aaaccttgta agacagttta agggagaagt gataaaggtt
     3841 agcagtaagt caaaagacta cttaaatccc cttgatataa acatgaacta tggcgatgga
     3901 gatgcacctc ttaaagacaa ggcaaatttc attatgtcca tgcttgaact tgtagttgga
     3961 ggaagcggac ttacggcaga agaaaagtcg gtaatagata ggtgccttcc taaaatttat
     4021 gaaaagtatt ttgaaaatcc gactcctgac aatatgccga ttcttcaaga cctatacgat
     4081 atgttaaaag ggcaggaaga aaaggttggt aagaagctgg caacggagat ggaaatatat
     4141 gtatcaggtt ctcttaatgt ctttaatcac aggtcaaatg tggacttaaa taagaagctg
     4201 ctttgctttg atattaaaga gcttggaagc cagcttaaaa aaatcggtat gcttgtcatt
     4261 caggatcagg tgtggaataa ggtatcgcaa aacagaggaa acaaggctac aaggtactat
     4321 atagatgaat ttcacttgct gttaaaagat gagcagacag cttcatactc ggttgagata
     4381 tggaagcgtt tcagaaaatg gggaggtatc ccgacgggta tcacgcagaa tgtcaaagac
     4441 ctgcttatga gtaaggaaat agaaaacatc tttgataata cggactttgt cttaatgcta
     4501 aatcaggctt cgggagatag agaaatctta gcaagaaaac ttaaaatctc acttccacag
     4561 cttcggtatg taactaactc caatgagggc gagggattac ttttctttgg aaataccatt
     4621 gtgcctttcc ttgataaatt tccgaaagat accattcttt atcagaagat gactaccaag
     4681 cctgaagaag tgaggtagct tatggatagg aagctgaaaa aggattttag agaaaggcat
     4741 aaggcaagtc ttgaaagaga gatgcttaga gctgaaacaa gtgccatacc tgaagaaagt
     4801 aagctaaagc ataacgatga ttacagagga aaaatcgtcc atgataaaga aagatttcag
     4861 gataaggtac acgaaaagat aagtaaggta agctctgata atgagcaagc acaggggact
     4921 tccaaaagaa atacaaagca tagagcttct gataaggaaa gtgtaaatga agcaggaaag
     4981 gctgactatg atactgaggt aaagaacggg aaaatctatg attctttagg acaagacctt
     5041 gataatgatg gaatcataga cagatacgat aatgatttta gggacagcga ctactttgaa
     5101 tcaacttatg atgtagagga taatctacct caaaaagaaa aatcattaga aaatccctct
     5161 aaaaatcata aggctcaaaa gagtaagtat aagaggaaaa actattccgg aagcctctat
     5221 acaagaaaaa aggacgatgt accaaaagaa aataaatctg aaggtaaaag aacagggaaa
     5281 gatactctaa gtgaaaaaga aaatatcagc ctatcaaaag accaaaagaa aaaggtcaaa
     5341 aaggatatgg taaaagtatc tgccctgtca gggcttgcca aaggaagtga aaccgtaaga
     5401 gattaccttt ctcatggaag cgatgaaaat aaaggcgtag aagcaggaga aaagacggcg
     5461 gatgcaagtt ccaagctcat tcatggtatt aagagatact cagataagaa aagagctaaa
     5521 aaaggatatg atcttacaaa taaggactac aaaatcagaa agcgtaaatc caagttagag
     5581 tttcgtgatg ccaaagagga gctaaaaaag acagatgaat ataaaagagc aagtgcctat
     5641 aaaagatttc aaaagaaaaa tcaggtaaag gcagcgattt ctcgtgagaa taagtcaaga
     5701 cttagagatc ggattaaaga gggacttatt ggaacgctga aaagctcaaa ggatatgatt
     5761 atccgaaaag ccaaaggact gatgcttatc ttcataggta tcattatctt gggaactttt
     5821 gtgattaact ttgcaggaac aggtatgaca ggctttatga actccacaag ctctgttctt
     5881 acaacaagct atttatcaaa gccaaatgtc ctaagtgaaa tcaatcagaa gttttctgct
     5941 atggagagtg agcttcaaag tgaagttgat catgtagaag aaaattatcc cggatatgat
     6001 gaatatatct taaacaacac agagtacatc ggtcataatg tccatgagct tttatcctac
     6061 attacatcaa gatgcggaga ggtaaagaat gtatcggaag tagaatccat attaaaagaa
     6121 ttgtttgagt ccatgtatga ccttgaatac agggaagaaa ttgaaatcag atacaggaca
     6181 gttacagaaa cctataccga tgaagatggc aatgaatata ccgaaagcca cgaggaaccc
     6241 tatgagtaca aaaaactcat tgtaacgctt cataaaaaag agatggatag cattatccga
     6301 aaggtatttg caaactatcc agataatcta aaacactatg aagccttatt ccttgcacaa
     6361 ggaaatatgg gagaagcctt tggtaattct gaccttatca gtgctaatgg tggtgtaggt
     6421 ggtggaaaag agtatgaggc atctacggaa gtacaaaaga agattgttaa tgctgcatac
     6481 atcacaccat ctccgggtgc aggctggtgt gccatgtggg tatcacaggt ctaccaaaat
     6541 gctggacttg gatatatcgg aggaaacgct aatgatatgt atcgaaacta tacctttaca
     6601 tcagacaggt caaagctaaa agtaggaatg cttgtggcgg tagaaagcag cagtagcgga
     6661 agcacagcag gacttaccta tggtcatgtc ggaatctaca tcggggacgg taaggttatt
     6721 gataacatcg gtcgaataag agtaactacc ttagatgatt ggattgcgac tttttgtcaa
     6781 catcatccgg taggctttgg ttttccgcca aatgtaaaca gataaggagg gaacaatgtg
     6841 aaaaaagaac taacagcagt aaaaaacaga ataaagaagt taaaggataa aaaggctctg
     6901 attgatgaag aattggagcc tttatttatt cgtgaagaag aacttgaaaa tgaagaaatt
     6961 attgccattt gtagaaagaa caacatcaca atttctgatt tgatggcaaa ggtaaacaga
     7021 gaaaaagcag aactgaaaaa ggagaggaca aatgaaaacc agtttgaaaa agaataagaa
     7081 gttttggaca gcagcacttg cagtgattgt aagtattagc tgcattttag gactttggac
     7141 ggttgtgtat gctcaggagc aaagatctga agttcctaca aaaaacgaag ctgttcaaac
     7201 ggaagtggaa gtaaatgtaa agtatatctt tgaagatgaa aaagtttata aagaagaaaa
     7261 gattaaggca gagaaaggac agcttcttga tagcggtgat cttccaatgc tccctgatga
     7321 tatgaaattc attgacgaat tcctgtttta tgaggtaaag ggagatggaa aagatgagat
     7381 tatccgtaag gtagcaaaga ctgaggttaa ggataaacaa actcaaacgg aagaagaaaa
     7441 accaaagcag gacacaagca cgcagacgga agataaaaag acagaggaca agaaaacaca
     7501 gacagagctt tctaaagacg atatttcaaa aatggaaaaa gaggctaagg agcttcagga
     7561 taaacttgat aagttaaatg gtgagcttaa ggacaaggat aaattaagcg ataagcagaa
     7621 agaaaaaatc aaagaccttg aagatgaagt cgaaaacctg aaagaaaaaa tgaagaaaga
     7681 taagggaaat aaagacttat cagaagatat aaaaaaggaa atagataagc tgacggaaaa
     7741 agttaaagag cttgagaaaa aggctgcgga aacaaataaa gctcctgtaa catcacagtc
     7801 aattacaccg attagtccta tttccggtat taaaacaagt tcaggtattt ctcctcaaac
     7861 accacagtcc tctgtaagta gtaccggcaa aggctcatcg gattcggtaa actcaggcag
     7921 tgctacaaag gatactggta aaacggaagt aaaggagaaa gaaaaggaag ttcgctatcc
     7981 aaataagctg acagcaaaag ctcctgccaa taacagtcag gattcatcaa tggactctgc
     8041 aagcaaaagt gtaaatacca ataagggtgt ggcttccgct ccgtcaaagg caagaggaag
     8101 cgttatagaa aataaggata atgcgaataa ggactacccg attcatcatg gagatagcag
     8161 cgataataaa gaaacagata tgtattcagc agatgcaagg cagtttatta cctttcaaac
     8221 gaaaaacggt aagacttttc atcttatcat caatcacgat gaggatagtg agaatgtaat
     8281 gcttttaaca gaagtatctg aagatgacct acttaacatg gtggagaaaa aagaagcacc
     8341 aaggcaggaa gtagtaaaag aagaacctgt taaggaagaa gtaaagcctg agaagaagga
     8401 cgaaaagagt aatttaggaa cctatattat tttgcttctt gtagtaggtg gtgcattagg
     8461 agcaggctac tattttaagg ttgtgaaaaa gaaagaagac aaagaacttg aagccttaga
     8521 ggaggaagat gatgatttct tttctgaagc agaaagtgaa gaagaaataa atgatgcaga
     8581 tgaagtagaa gatgaagaat aaacgcacct aaaaacatat tattttgggt gcaaagttag
     8641 ggcgggagag taacatcttt cgccctattt tgatttataa caggaggaaa acacagatga
     8701 agttagttat tgcagaaaag ccgagtgttg caatctccat tgcaaaggtt attggagcaa
     8761 ataaaaagaa agacggatat tatgagggaa atggatatag ggtaagctgg tgcgttggac
     8821 atttaattca gatggcaaat ccggatgttt atgatgaaaa gtatgcgaag tggaatatgg
     8881 ctgatttacc gattattcca aaggaatata agtatgaggt agcaaagtca accaagaaac
     8941 agtttgctat acttaaaaag ctgctgaatg ataaagagat tgatacggtt atcaatgcgt
     9001 gcgacgcagg tagagaagga gagagtattt ttagacttgt atataatcag gcaaattgca
     9061 aaaagaagat gaaacgcctt tggatttctt caatggaaga tagtgccatt aaagagggat
     9121 ttgataatat aaaagacgga aaggactatg ataatctttt tgaatcggca caggcaagag
     9181 ccattgcgga ttggttagtc gggatgaata ttagtaggct ctactcttgc ctttacaaac
     9241 agaattattc tgtgggcaga gtacaaacac ctacccttgc catgatcgta aaaagagatg
     9301 atgagatagc aaactttaaa aaggaaaaat actatacggt agaactttct atgaacggat
     9361 ttacattatc gacagatagg attgatgatg aaatcgcagc agagcagctc ttaaatttag
     9421 tgggcgataa gattgaaatt accgatgtca ttcaaaagga aaaaatcaca aagcctgatt
     9481 tacctttcga tttgacaacg cttcaaaggg agtgcaataa atattttgga tattcagcta
     9541 aacagacgct tgattatgct caaagtcttt atgaaaagaa gctcatcacc tatccaagat
     9601 cagacagcag atgtttaacg gaagatatga ttgtaaatac agttaataac attttgggta
     9661 agaatgattt tgacacagag cgtatcaagg ctgtgtttaa ctctaaaaag gttacggatc
     9721 atcatgcaat tattccgaca gtaagctcac tgagtgaaga tttatcaggc attcctgagg
     9781 gtgaagcaaa ggtatatagg cttatatccg ataaatttca tgcaagcgta gggtatccgt
     9841 taattgagaa cactacaaaa attgtagctg tatttgatgg ttttgaattt acaagtaccg
     9901 gtaaggtaat taaagatgag gggtttagca aataccttaa agaatacaaa tcaaaacaga
     9961 gtgaagatgc tgtaatgccc gatataagtg ttggtgatgt tttaagcatt gaaaataaag
    10021 agataaaaga aaaattcacc caacctccga aacactttac tgaagatact cttcttaagt
    10081 ctatggagat tgcaggaaat gacgcacttg aaaaaggtgt agaagtggaa agaaaaggac
    10141 ttggaacgcc tgcaacgagg gcagggatta ttgaaaactt aatctttaag ggatttgtag
    10201 aaagagataa gaagaatttg attgccacgc ataaaggaat tagccttgta acgattgtag
    10261 ctgataactt taagtcggca gaaacgacag cgaagtggga aatggaatta tccgatattg
    10321 ctcaaggcaa atcttcaaag gaagaatttt tgaaagatat tgaaaatgag ataaaagagg
    10381 ctgttctgac atatagcaag taagtaggga ttaatttcag agtggaaaaa atgtcctaaa
    10441 agtgctataa tcttttgtag gaaaagtagg gcgaaaggaa gtaagtatga aagatatatt
    10501 tatggatacc gcaaaagtta tggcaaaagg acaggttact attccgaaaa ggataaggga
    10561 acttttgaat ttagaaaatg gagactatgt tacttttgtg gttaataaag ataaagttga
    10621 aattcaaaat tccaatgttt ttatcgaaga aaacattaag aagtaaaggc ggtgaaatga
    10681 ctatatgacg atagatgaaa taaagaagtt aattcaagtc ggagaaaaga tagatgtcga
    10741 atttaaagaa tcaaaaaatg ct
//
LOCUS       DARYSY010000061        10484 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYSY010000061 DARYSY010000000
VERSION     DARYSY010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10484
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            88..702
                     /locus_tag="TVR04_001654"
     CDS             88..702
                     /locus_tag="TVR04_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270328.1"
                     /translation="MVINMISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAI
                     KNNTDDADGMYFVQSHEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPE
                     EETLFRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIK
                     YGLGKMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            1569..2726
                     /locus_tag="TVR04_001655"
     CDS             1569..2726
                     /locus_tag="TVR04_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270329.1"
                     /translation="MTQKLRQNKHARKYGLCSAAIALATVASLGAAGSAKAEMTRSAA
                     DYPDPAKEITYSRWRTEDNGARQYLHKLKEFLVPYLEELEKQAKVPGPQGPAGPQGEK
                     GDKGDQGPAGPQGPKGDKGDRGENGHNGFNGQNGPEGRGQDGQGGQGERGQNGQNGQG
                     ERGQNGQGGQGEHGQDGQSGQGEHGRNGQGGQGERGRNGQGGQGEHGRNGQSGQGEHG
                     RNGQSGQGEHGRNGQSGQGLNGQGMNGLGMNGQGMNGQGLNGQGLNGQGMNGLGMNGQ
                     GLNGQGMNGLGMNGQGMNGQGLNGQGLNGQGMNGLGMNGQGLNGQGMNGLGLSALGLS
                     GHKSYYGKDASPAVQKAALPLTGDASHPFFTVAALGVIASAGVLALTGKKN"
     gene            complement(3129..3494)
                     /locus_tag="TVR04_001656"
     CDS             complement(3129..3494)
                     /locus_tag="TVR04_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1270330.1"
                     /translation="MIKVFETRVTAIGSEAADMINAANMLILFGQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFA"
     gene            complement(3528..4520)
                     /locus_tag="TVR04_001657"
     CDS             complement(3528..4520)
                     /locus_tag="TVR04_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1270331.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIADLTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSAPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(4536..5081)
                     /gene="srlA"
                     /locus_tag="TVR04_001658"
     CDS             complement(4536..5081)
                     /gene="srlA"
                     /locus_tag="TVR04_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1270332.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMILPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKTIEL"
     gene            complement(5217..5678)
                     /locus_tag="TVR04_001659"
     CDS             complement(5217..5678)
                     /locus_tag="TVR04_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1270333.1"
                     /translation="MSFMVIFGLFVIAAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWPLQAKQLLARFK"
     gene            complement(5678..7546)
                     /locus_tag="TVR04_001660"
     CDS             complement(5678..7546)
                     /locus_tag="TVR04_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1270334.1"
                     /translation="MTLVNRWYRILEPLVAQNQMAFEELRLQLDVSAQTLARSIDQLN
                     DILDGDATITQQGAFLQLQVYDYARLETILAGSLRKASDFNSASKRVAYLLKRLLQSS
                     SALVIDDLADEIGVSRSTINKDLKAAKALARTYSVMIQGKPNHGIQAVGTELNLRLLY
                     VHEVYKYFEPQGLCGDSLFFLDELYQTYQLPRKIQELLTKSLAITIERMRQGRYLTDP
                     IPYYSNEVDSNAFMEELVYHIELAYQLSLSQYERQFISFPLNIQYIEGLAYQERPLQQ
                     SIVRLYSKMIEHIKASLLVTIDQDKLFVALHTHLKLLVNRLIFHVQANDIFHGEIRYK
                     YPLAFDMANVAAQVLAEEFDCAIELSECSYLALYFEMMMQDAEHVTEPTVKKIAVVCT
                     TGRGTANMICRRLSKVLGPDLLISQFSEEQFNPDDNDHYFAIFTTVPLKFGQLKSPVV
                     QITNLFDDQWLQNEWRRVHHYHQKNLATITLHFARLSKGKAYTDYLTEMAELLEEKQL
                     VDRQFGQRLLEREALQSTLFGNRIAFPHTINDKETKTVLLLGLLDEPYREHDCLVEFI
                     FLVAIPKRVEAQMEADLLEIYDDIFKIASDDRLQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(7569..8369)
                     /locus_tag="TVR04_001661"
     CDS             complement(7569..8369)
                     /locus_tag="TVR04_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1270335.1"
                     /translation="MTDWLNISGKTVIVTGGSSGIGQAIVDELLALGVKVANFDIVDN
                     GIRHDHLLFIKVDVTSRQEVEAAVDQVVEHFGTVDALVNNAGINIPRLLVDPKDPHGK
                     YELDDKTFESITMINQKGLFLVSQAVGRILVAKKAGVIINMASEAGLEGSEGQSAYAA
                     TKAAVYSYTRSWAKELGKHGIRVVGIAPGIMEATGLRTLAYEEALGYTRGKTVDQIRA
                     GYASTSTTPLGRSGKLSEVADLVAYYISDRSSYITGITTNVAGGKTRG"
     gene            complement(8956..10305)
                     /locus_tag="TVR04_001662"
     CDS             complement(8956..10305)
                     /locus_tag="TVR04_001662"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1270336.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         3153 a         2366 c         2141 g         2824 t
ORIGIN      
        1 ttcaaaaaca gtcttgtttt ttaatttatt aatgttaaac ttaaattgtt gaaagactag
       61 tctaaacatt tatttttaaa gaagggcatg gtgatcaata tgatttctgt aaagaaaaat
      121 ttatgtcgct taggtgtttt gtctagtagt ttattacttt taacagctgc aacgactcca
      181 tctgtcattg cttttgcgga tattcaaaca agtgccataa aaaataatac agatgacgca
      241 gatggtatgt attttgtcca aagtcatgaa atgtctgtag aagataaaga attgcttgtt
      301 cgaaatgtta aagcaaatca tcctacagtt tctgaagatt ttatcagaga agttattgaa
      361 agacaattag taggtgatta tacattacct gaagaagaga ctcttttccg ctcagcatgg
      421 caaggggtta cagtagatca attgggagca gctctagatg tggctattgg tatggcatta
      481 acaggtggag ctggatcaat tgctgctggt gttttgagag tcggaaaaag agaagctgtt
      541 ggtcgggtaa aatcaattct aattaaatat gggctaggta aaatgatagc tgaaattcca
      601 gtcgattaca tgttaaattt attatcgcca ggatatcata tagctagata tattgatagt
      661 attgatacag ttcctaataa taatagaatt aacctttggt aagttaggaa atttagtact
      721 gtgaaaaaaa tttatatttt atattttgtg ctttattgct tattatacct tgtcatatca
      781 ttattaatta gctatggtat gtcccatttt cttaacatgg aatttaaatg gtggaataaa
      841 ttagctatat ctctaacatc tttatatatt atttatcaaa tgctgaaaaa ggataaatta
      901 attaaataat caactaatgt acaagttgtc tttaagctga aaagaggcta tcaacagcct
      961 ctttttacct tataggcttg atttttagac agcctttagt aaaggcctat aggctgacac
     1021 cagctgtaaa ggctagctaa gcctctcttt atgcaggaaa cctagaggct ttctttgccc
     1081 caaagcacca gctagtggtg gagaccctta agctttctcc tgtacaatgt agctatccta
     1141 acgagagcgg ttcgtcacca gaccgctaag agaatgaaat ctcccgtttt cttttatcat
     1201 catctcttgg acctttagtg catttgcgct aaaggtcttt ttagctgctt atgacataac
     1261 cgacatggga gctgacagac aagcagctca tcatcttcta ataacatcaa tatgtaactg
     1321 tcattaatgc aagcaggtac agcatcagac acccttaaaa agccgctgtt gccaactgat
     1381 cccttgcctg tgggtgatgc acaatttcga tagaccgagt taaaaaatca gattattagt
     1441 ctcaaaatta aaaaaaaacg aaagcttgga aacaaattgc taaaaacata ttcacagtct
     1501 gcaagcctca tgttagaatt tcgtttggga aaggaaaaaa tctaattcta agacaaaagg
     1561 agagaaacat gacacaaaaa ttaagacaaa acaagcatgc tcgtaaatac ggactatgct
     1621 cagcagccat cgccctagcg acagtagcca gcttaggagc agctggtagc gctaaagctg
     1681 aaatgacaag atcagctgca gactatccag atcctgcaaa agaaattaca tatagccgtt
     1741 ggcgcactga agataatggt gctagacaat acctccataa actaaaagag tttttagtac
     1801 cgtatttaga agaattagaa aaacaagcta aggtacctgg acctcaagga cctgccggac
     1861 ctcaaggaga aaaaggagac aaaggtgacc aaggacctgc cggacctcaa ggacctaaag
     1921 gagataaggg tgaccgaggc gaaaatggac acaatggatt caatggacaa aatggaccag
     1981 aagggcgtgg tcaagacgga caaggtggcc aaggagagcg tggtcaaaat ggacaaaatg
     2041 gccaaggaga gcgtggtcaa aatggacaag gtggccaagg agagcatggt caagacggac
     2101 aaagtggcca aggagagcat ggccgcaatg gacaaggtgg tcaaggagag cgtggccgca
     2161 atggacaagg tggccaagga gagcatggcc gcaatggaca aagtggtcaa ggagagcatg
     2221 gccgcaatgg acaaagtggt caaggagagc atggccgcaa tggacaaagt ggtcaaggct
     2281 tgaacggtca aggtatgaat ggactaggta tgaacggtca aggtatgaac ggtcaaggct
     2341 tgaacggtca aggcttgaac ggtcaaggta tgaatggact aggtatgaac ggtcaaggct
     2401 tgaacggtca aggtatgaat ggactaggta tgaacggtca aggtatgaac ggtcaaggct
     2461 tgaacggtca aggcttgaac ggtcaaggta tgaatggact aggtatgaac ggtcaaggct
     2521 tgaacggtca aggtatgaat ggactaggtt tgagtgcact aggcttgagt ggtcataaga
     2581 gttactatgg aaaagacgct agtccagcag ttcaaaaggc agcattgcca ttgacaggag
     2641 acgcaagcca tccattcttt actgttgcag cccttggcgt tatcgctagc gccggcgtgt
     2701 tagcattaac aggcaagaaa aactaaatca gccattaccc ctttcccctt aagtaatgga
     2761 ctagtaacag cttttctcat ctctactgca cctttcccct taggtaatga gctagtaaca
     2821 gcttttctca tctctattgc acctttcccc tcaggcaatg agctaagaat ggcttttctc
     2881 atctctattt agacagcatt gccttaagaa gatgatcaga gatgacctaa gttcaaaaag
     2941 aggctatgaa agcctctttt ttttgatgat atagataagc ccaatgctcc cttagcagag
     3001 ctcttctgtg agatgacctt atcacctgac attagctgct tagcttatgc ctacagctaa
     3061 aggaaatgcc ctgcaaggat agcagcactt agcctgctgg tctacggcgt gtctcagctg
     3121 cacctaagct aagcaaagat ttgtactagg ctaccttgtc tgacctgcgg cagccctttg
     3181 cccttgacat gcagagtacc gggaagagag ctggctgtgg agccatcaaa agaaatggtt
     3241 atatgcccta gctgagcaag atttttttca acaacagcac ctactgctgt gatgtcatat
     3301 gccatttgat caatgactag ctgaccacca gcagagatag acccagacac ttgcttgttg
     3361 tcaatcgtat agcaaaagtc tgccaagtct gcgggtgctc cctgaccaaa aagaataagc
     3421 atattggcag cattaatcat gtctgccgcc tccgatccaa tagcggtaac tcttgtttca
     3481 aatactttta tcatacattc tctctcttcc tatcacacga tagctcctta ctgatacaaa
     3541 ccaatacttg caatccaagc aacaacaacc cgaggaacac catttaaaaa gcgtgaataa
     3601 agcacagatg gcacaccaac ctctactgtc tcagcattag cctctgataa accaagcgct
     3661 actggaatga aatcacagcc attttgcgta ttaatagcaa aaagtgcagg aagagccatt
     3721 tgtggtggaa tagtgccttt tccaatctca acaccaatga gcgttccgat gatttgacta
     3781 ataaccgcac caggtcctaa cagcggtgat aaaaatggca acgaacagat aaagccaatg
     3841 ataatcaagc cccaaatatt accagccaac ggtaccatga gcttagccag ccaatttcca
     3901 acaccagagc cttggataaa accaattaaa agagagacaa atgccatgaa tggcagaatc
     3961 gtattgatta aggtctggat agcctcacgc gccgcttggt tgaagatagc aactacctta
     4021 cctgctccca taccaatgcg agccacaaag ctgctttctg cgcgctgctc agtaatcttt
     4081 ttgctagtat catagctgct agcctttgga gctgatgact ccttagcact agcaacatga
     4141 gcctgagcgt cactggctgt gatttgctca agacctacag cagacacgta aatgtcctcg
     4201 gtaatgtact gtgccaaggg accgctttta cctgtcgcca cgatattaat ggttggaatg
     4261 ccttttttag ggtaaatacc gcagcgtagg gtgccgccac aatccacaat agctagggct
     4321 atctcatcat cagggattga ggtcacaaag ccattgaccg cctccatacc tgttagatca
     4381 gcaattttat cgacaatgtc aggctttttt ccaccgccag taatatagat aaatttgtgc
     4441 ttagcttctg ttggtgtaat ggttaatggc ccaccatagc caccgctccc cttaacaact
     4501 gtaatactgt gataagtcat catgctacct ctcttctata actcaatcgt cttacttaat
     4561 gtcacaccct gctgcttggc cacgtaggct gtcgtaaagt cagttaccca gccaccaaca
     4621 aagttcatga ttaacccaac caagaggtaa cgaatcgcca agtccatttg gctcaagcct
     4681 agagtcttga tacctgaggc aatacctaac cagacaaaca attctcccgg attaatgtgt
     4741 ggaaagacac cgtttgacgt atgacaaaat tgcatttgag cggcaacata gcttggcttg
     4801 taatactcag gcataaaacg tcccatactg attgccattg gattacccag cataaaggct
     4861 gaaataaaag gtaatatcat gtagcgactg atagggtttt tagcagagat tttcgccaat
     4921 tgattgaccc tttgatctcc taaaatacca attaaggcat tcattgcaac cagcagcatc
     4981 aagaccaccg gcacaatgcc agtcatccag ctgacaaagg tttcaccacc aagctggaag
     5041 agcttcataa agccttccgc aaatcttgtt atcatttcca taaataaact cctcatatga
     5101 tgtacttaca agcaagacaa tacaaatgta ctgcctgctt gataatagct gcttgagctg
     5161 gactcaaaac agcttttatg ttgacaaggc aagcaatcaa tcctgctttt ggcaccttac
     5221 ttgaagcgtg ccagcagctg cttggcctgt aggggccaat caaaggctga ggcatatttt
     5281 ggcgcgtcct catagacccc tgcctcaacc ctcaagaaga cctctcttgc gtcctcaata
     5341 gccaagcgca gcaatttatt ttctcgtcta atcaagggat tgtagcgatc aaaataatga
     5401 atatcctgac cgatataagc tggcattggc ttaaacctag ctgccactgt cacaccctgc
     5461 atttgcctag catctaatac cttacctgac tgatccaagg caaacatgac aatggttccg
     5521 gccctgattt tcccggctct acggccaata gcaacgcgcc cctgtcgtct aagactggca
     5581 taaacagcat tgaagtgctt aagctgtctc agacctagca ataattgaaa aaggtaagca
     5641 gctatgacaa atagtccaaa aataaccata aaactcatta aaaaactcct ttttccttgg
     5701 taaatgcaat aaactcagct tgacttttta ggctccttag ctccgcctga agcctatcat
     5761 cgcttgctat tttgaaaata tcatcataaa tttccaagag atcagcctcc atctgcgctt
     5821 caaccctctt gggaatagcc actagaaaaa taaactccac cagacagtca tgctcacgat
     5881 aaggctcgtc taatagaccc agcagcagga cagtctttgt ttccttgtca ttaatcgtat
     5941 gtggaaaggc aatgcgattg ccaaataagg ttgactgcag ggcctcacgc tctaacaggc
     6001 gttgaccaaa ctgcctgtca accagctgct tttcctcaag cagctccgcc atttcagtca
     6061 ggtagtcagt gtaggccttc ccctttgaca gacgagcaaa gtgtagggtg atggtcgcca
     6121 ggtttttctg gtgataatga tgtaccctgc gccattcatt ttgcagccac tggtcatcaa
     6181 acagatttgt gatttggaca acaggagatt ttagctgacc aaacttcagc ggcacagtgg
     6241 tgaatatggc aaaatagtga tcattgtcat caggattgaa ttgctcctca gagaattgtg
     6301 agatcaacaa atcaggacct agcaccttgc tcaagcgacg acaaatcata ttggcagtgc
     6361 cacgacctgt cgtgcagaca actgcaattt ttttcactgt tggctctgtc acatgctcag
     6421 cgtcttgcat catcatttca aaataaaggg ccaagtagct gcactcagat aattctatgg
     6481 cacagtcaaa ctcctctgct aagacctgag ctgcgacatt ggccatatca aaggccaagg
     6541 ggtatttgta tctaatttct ccatgaaaaa tatcattggc ttgaacatga aaaatcaaac
     6601 gattcaccaa gagcttcaaa tgcgtatgca aagcaacaaa aagcttgtct tgatcaatag
     6661 ttaccaagag actggccttg atgtgctcaa tcatttttga ataaagcctg acaatgctct
     6721 gttgcagagg cctttcttga taggctagac cctcgatgta ttggatattc aagggaaagc
     6781 taataaactg gcgctcgtat tgactcagtg acagctgata ggctagctcg atgtgataga
     6841 ccagctcctc cataaaggca ttggaatcaa cctcattgct atagtaagga ataggatctg
     6901 tcagatacct gccctgacgc attcgctcaa tggttatcgc aaggctcttg gtcaaaagct
     6961 cttggatttt gcgaggaagc tggtaggtct gatacagctc atctagaaaa aacaagctat
     7021 caccacacaa gccctgcggc tcaaagtatt tgtaaacctc atgaacataa agcagccgaa
     7081 ggttcaactc agtgccaaca gcctgtatac catgattggg cttgccctga atcatgaccg
     7141 aataggttct agcaagggct ttggctgcct ttaggtcttt attgatcgtg ctacgactga
     7201 cgccaatctc atcagccaaa tcatcaatga ctaaagctga ggagctttgc agtagccttt
     7261 ttaaaagata agctacccgc ttactggccg aattaaaatc actagcctta cgtaaactac
     7321 cagctaatat cgtctctaat ctagcataat catagacctg cagctgcaaa aaggcgcctt
     7381 gttgggtgat ggtcgcatct ccatctaaaa tgtcattgag ctgatcaatg ctccttgcaa
     7441 gggtttgtgc acttacatct aattgaagcc gaagctcttc aaaagccatt tgattttggg
     7501 caactaaggg ctctaaaatg cgataccaac ggttaactaa tgtcacgtcc tacctctctt
     7561 gtcagatact agcctctcgt tttaccacct gctacatttg ttgtaatgcc cgtaatataa
     7621 cttgagcgat ctgatatata ataagcaaca agatctgcca cttcacttaa tttgccgctt
     7681 cgtcctaaag gtgttgtact ggtcgaagca tagcccgcac gaatctggtc aacggttttt
     7741 cctctagtat aacctaaagc ctcttcataa gccaatgtcc gcagtcctgt cgcctccata
     7801 atacctggtg caataccgac aactcgaatg ccatgcttgc ctaattcctt ggcccaagag
     7861 cgtgtatagc tgtaaacagc tgccttagtt gccgcatagg cgctttgccc ttctgagcct
     7921 tctagacctg cctcagaggc catgttaata atgacacctg cttttttagc caccaaaatg
     7981 cgcccaacag cctgactaac caaaaacaag cccttttgat taatcattgt tatgctctcg
     8041 aaggtcttat cgtccagctc atatttccca tgaggatcct taggatcaac tagcaatctt
     8101 ggaatattga ttcctgcatt gttgaccaga gcgtcaaccg ttccaaaatg ctctaccacc
     8161 tgatccacag ctgcctctac ttcttgacgt gacgtcacat caaccttgat aaatagcaag
     8221 tgatcatgcc tgatgccatt gtcaacaata tcaaagttag ccaccttaac gcctaaggcc
     8281 aagagctcat caacaatggc ctgaccaatg cctgatgagc ctccagtgac aatcactgtc
     8341 ttacccgaaa tgtttaacca atctgtcata acagcctcct ttaaaagatt ttaacagctt
     8401 tattataaaa cgcttacaag atgatattaa gacagacttt ttttcatatt ctaaaaatat
     8461 catgaactaa ttgattaact cttacgaagc aatgacagcc catagcctat taccatagca
     8521 ctctaaagca gctcttagac cagctgatga tagctgattc ttgatcactt aagtctcctg
     8581 taagcataga cgaaaggctg gattgcctga tgggaatcgc cagttaaatc gcctgaccaa
     8641 tgctacttgc agcgtttgac atcgtctttt cacaaagtca cagcttagaa agctagcaga
     8701 ggagacaaaa gcaagacctt atcagctaac agcaacatat taaacgagca gccattgaga
     8761 ctgatcctac taagcataga gctccaaaag cctgacttaa atagtattca aaatagaaca
     8821 agagctctca agaacaataa cctagcgcac tacttgcctt gataagccta accgaccttg
     8881 aaaagaagca aaaaaaagag cctctcacga gactctttgt tatgttttag cagactagtc
     8941 tagctagctc tgtcattaca agcgtgcgtt gagcgctgct cctagctctt caaagcctgg
     9001 cttaccaaga agggcaaaca tgtttttctt gtaagcctca acacctggct gatcaaatgg
     9061 attgacccca ttgaggtagc ctgaaagggc aatagcaagc tcaaagaagt agatcgtata
     9121 gcctagtgta aattcatctt gctctggaag cgtgataaac atatttggca caccaccgtc
     9181 tgtatgggca agaaggacac catctgttgc ttttttgttg acaaagtcaa cgtctttgcc
     9241 ttgtaggtag ccaaggccat caagatcctc agccatttct gggataatca cattttgacg
     9301 tggcttatcc acacgaatca ctgtctcaaa gaggttacgg tagccttctt ggataaattg
     9361 accaagagaa tgcaggtctg tcgagaaatt agctgaagtt gggtagatac ccttttggtc
     9421 cttgccttca gactcaccag ccagctgctt ccaccattcg ctaaaatact gcaatgatgg
     9481 ctcgtagttt gccaaaattt cagtcacata gcctttgcgg tagaggatat tgcggaccac
     9541 agcatattgg taagcgatgt tttctgagat tttatctgat gacaggtcct tacgagctgc
     9601 atttgctcct tccatcagcg cggtaatatc agcccctgat gctgcaattg gtagcaagcc
     9661 cacagctgtc agcactgaga aacggccacc aacattatct ggcacaacaa aggtttccca
     9721 atgatttgca tcagcctcaa ccttaacggc acccttgacc ttatcagttg tcgcatagat
     9781 acgcttgttg gcttcttctt gaccgtactt tttaacaagt aattctttaa agacacgaaa
     9841 ggcgattgca ggctctgttg ttgtaccaga cttagaaatc acgttaacag agaaatcttt
     9901 atcttgaaca tagtccacaa gatcagcaag atagcttgat gagatggagt taccagcata
     9961 aagaatttgt ggtgctttac gctcttttgc tgtttgtagg ttggcaaaat ggctgttcaa
    10021 aaagtcaatt gcagccttag caccaaggta agagccacca ataccaatca caacaagaac
    10081 gtcactgtca gccttaatct tctcagctgc tttaaggata cgagcaaatt cttctttgtc
    10141 atagttttca ggtaactcaa gccagcccaa gaaatctgat ccaggtccag tgccctgacg
    10201 tagtgcctga tcagcctctg ttacctgacc ttgtaaaaag tcaatttcat gctgtccggc
    10261 aaattgctca agaacctttg aataatcaaa tgtaatatgt gacattattt tactccctta
    10321 acttttaaag tttcattagt atcataacct tttctattca atatttcaat gtttttatat
    10381 ttaagaaaca ggtggctact cctagctacc cgataatcat ctcttttcaa aagctttttt
    10441 aatggcctag gttttctcac ctgcctcttt tggttgagcg atta
//
LOCUS       DARYSY010000062        10180 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYSY010000062 DARYSY010000000
VERSION     DARYSY010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10180
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(145..531)
                     /locus_tag="TVR04_001663"
     CDS             complement(145..531)
                     /locus_tag="TVR04_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1270337.1"
                     /translation="MTIEEMLDFHNVELAYFDNDLWPRPGIYVDEIKVVFVNRALSEA
                     SKRKVIFHELGHLEHDSNQYGRRHEEFELEANRYMIRCLLEDEFDRVEDKYEFNYLSF
                     MKRHNLKTITDEVMVISEYYNLLDAV"
     gene            complement(535..882)
                     /locus_tag="TVR04_001664"
     CDS             complement(535..882)
                     /locus_tag="TVR04_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270338.1"
                     /translation="MFSTFEKIKELAKKQGKSLGQVEEDLNYGRNTLYKIKNSTPNAE
                     RLGEIANYFNVSTDYLLGRTNNPTIAKDDQEYKSEDLRKMAENAKTFDGKPLTESDIE
                     AIKNIIEIYLKGR"
     gene            1639..1830
                     /locus_tag="TVR04_001665"
     CDS             1639..1830
                     /locus_tag="TVR04_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270339.1"
                     /translation="MSDNTVAVEKIKKYLLDNKLKQVDLAVTYNKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            1851..2081
                     /locus_tag="TVR04_001666"
     CDS             1851..2081
                     /locus_tag="TVR04_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270340.1"
                     /translation="MLNAILERNLMTDAEKQNYDALFINIFERLEKLEEGYDFSSVAT
                     TTEVQNSGGVQYRECQEDGTVVKTVSKRSLGY"
     gene            2147..2422
                     /locus_tag="TVR04_001667"
     CDS             2147..2422
                     /locus_tag="TVR04_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1270341.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKVKVMKMINNETEIYPLELNKKQVS
                     KMFGVDPKTFDARFNSHKDFPRIETGGREKYPRDLVIEWYHRNWSIT"
     gene            2419..2589
                     /locus_tag="TVR04_001668"
     CDS             2419..2589
                     /locus_tag="TVR04_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270342.1"
                     /translation="MNKLELFLLTTTVILAVIARVQHEVIKKHNSPENKRRIFREVAL
                     ENSKKWSAERYV"
     gene            2582..2788
                     /locus_tag="TVR04_001669"
     CDS             2582..2788
                     /locus_tag="TVR04_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270343.1"
                     /translation="MSKWELQKQLLANATDFESTVEALFELNELGEISDEELLLNLRS
                     SYRKYSEEKLCIIDKLIKLGGAER"
     gene            2785..3168
                     /locus_tag="TVR04_001670"
     CDS             2785..3168
                     /locus_tag="TVR04_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270344.1"
                     /translation="MTTFEKVISKLNRIEGELAKPESERRDNSYHLSALLGSIKQDLK
                     LMLWIELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRRN
                     FVKLAEKEFKGATLSWQEFLWGKKK"
     gene            3313..3516
                     /locus_tag="TVR04_001671"
     CDS             3313..3516
                     /locus_tag="TVR04_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270345.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            3604..3903
                     /locus_tag="TVR04_001672"
     CDS             3604..3903
                     /locus_tag="TVR04_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270346.1"
                     /translation="MIEVTFKAESMASVFDAMREALDMPKTATEDVVEEKSAPEKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            3903..5060
                     /locus_tag="TVR04_001673"
     CDS             3903..5060
                     /locus_tag="TVR04_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1270347.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKTFKENSDFYNEEMEEMTERYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVMEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNIVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVSRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            5074..5637
                     /locus_tag="TVR04_001674"
     CDS             5074..5637
                     /locus_tag="TVR04_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1270348.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHMFMS
                     ISSKTKPQIIDKYKNSVDSAEEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            5680..7602
                     /locus_tag="TVR04_001675"
     CDS             5680..7602
                     /locus_tag="TVR04_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL1270349.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLERCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKAITGLANPNSRAQLLPWLKEHGYSANGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDARGYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RLRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGHGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPDWAEG
                     LPLNSEGYITKYYMKD"
     gene            7607..9991
                     /locus_tag="TVR04_001676"
     CDS             7607..9991
                     /locus_tag="TVR04_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1270350.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVCDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVAYAPEATCETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMGEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRLKEEF"
BASE COUNT         3303 a         1847 c         2280 g         2750 t
ORIGIN      
        1 caattttatc ccaatactct tctagtagag ctgaccatgt aggaaaatct tctaaatatc
       61 tttttgatat cccagaaccg atgaatacga ttggatagct attattctca atgatatctt
      121 ttatcatttt tattcctcca atattcacac cgcatccagc agattataat actcactaat
      181 aaccatgact tcatcagtta tggtttttaa gttgtgcctt ttcataaaag ataagtaatt
      241 gaactcatat ttatcttcta ctctatcaaa ttcgtcttca agtaaacatc tgatcatgta
      301 tctattagct tcaagttcaa attcctcgtg tctgcgccca tattggttag agtcgtgttc
      361 caagtgccca agctcgtgaa aaataacttt cctcttagat gcctctgata atgctctatt
      421 aacaaagaca acttttattt catcaacata tatccccgga cgtggccata aatcattgtc
      481 aaaataagct aattctacat tatggaagtc taacatctcc tcaatagtca tagactatct
      541 tcccttcaag taaatttcaa taatattttt aatggcttca atatccgatt cggtaagcgg
      601 cttaccatca aatgtttttg cgttttcggc catttttcgc agatcttcag atttatactc
      661 ttggtcatct tttgcaatag taggattatt tgtcctgcca agtaaatagt cggtagaaac
      721 attaaagtag ttagctattt ctcctagcct ctctgcgttc ggagttgagt tctttatttt
      781 atacagcgta tttctgccgt agtttaagtc ctcttctacc tgtccgagcg atttaccttg
      841 tttttttgcc agttctttta ttttttcgaa tgttgaaaac attgatatat caacctttcc
      901 gagcatgaca aaaaatattt tagaaaattt ggtgtaaaat tattgacttt taccaaattt
      961 ggtgtaaaat agtttttgta agatagttag ttagtaaaaa acgaagttaa actttttaca
     1021 aatcttttta agtagttggg gaactgcgga atataaaaga gttataaagg ttataactag
     1081 gtttttctta tgccttcatt ttatcttata tggtgtaaag tgtcaactgt ttttaagaaa
     1141 atttactaac tttcttgctt acaaaaataa aacaccacct agctgctatc tagatggtgc
     1201 tacggaaatt attctgctca aactaatagc agtagtcaac aacacttcac cggtatcgtc
     1261 cccggcactg tagttggagt agaaaatgat tctcgatttt gatttcctat tcttcgtcgc
     1321 ttttgcgagc gacagccagt ttgcaatttc tgtggtcgtc cggccaggac gccaatgaag
     1381 atataggaac ccctattgaa tcttgctagt caagtgcggt aggcaaaagg aaaacctaca
     1441 aacgaatcca tcttctactg agacacagtc tccttcaaaa actcggacaa atgatacgtc
     1501 ctcctttcat acaaagggta cttacattat atatttgtaa gtcgaaaaaa tcaagatgga
     1561 tactgtttga atcgagcaga ataacgtttc cgttaagttg ttttaaataa atctacttac
     1621 tagaaaggag tctaacgcat gtcagacaac acagtcgctg ttgaaaaaat taagaagtat
     1681 ctgcttgaca ataagctaaa acaagttgac ttagcagtta cctataataa agaaccgcaa
     1741 gatgtggcga atatcttagc tggaagaaaa aaagatccag catcaaatcg ttttgtcttg
     1801 aaagttattt cagatttgaa aattagatag aagagaatta tatgaaccaa ttgcttaacg
     1861 caatactaga aaggaacctt atgacagacg cagaaaaaca aaactatgat gcccttttca
     1921 ttaatatttt tgaacgttta gaaaaactgg aggaaggcta tgattttagc tccgtagcta
     1981 caactacgga ggtccaaaat agcggcggtg ttcaatatcg tgaatgccaa gaagacggaa
     2041 ctgtagtcaa aacagtatcc aagaggagct taggctactg atgattatat caaaaaagtc
     2101 cgacgggaat cggactcaac aataatactt atgaggtaat tttatcatgg atagcagatt
     2161 attacaaatg ctagatgagt ttgaagcggg cctgattgat cgcaaggtca aagtcatgaa
     2221 aatgattaac aacgagacgg aaatttatcc gctagaactc aataaaaagc aagtcagtaa
     2281 gatgtttggg gttgacccta aaacatttga cgcaagattt aacagccaca aagatttccc
     2341 gcgcatcgaa acgggaggtc gggaaaaata tccacgagat ttggtcattg agtggtatca
     2401 caggaattgg agtataacat gaacaaatta gaattatttt tattaacaac aaccgtcatc
     2461 ttagcggtca ttgctagggt gcaacacgaa gtcatcaaaa aacacaattc gccagagaat
     2521 aaacgcagaa tttttaggga agtggcttta gaaaacagca agaaatggag tgcagaacgt
     2581 tatgtctaaa tgggaattac aaaagcaact gttggctaat gcgacagatt ttgagagtac
     2641 agtagaagct ctgtttgagt taaatgaatt gggcgaaatc tcggacgagg agctcttgtt
     2701 aaatttgaga agtagctaca ggaaatactc agaggaaaaa ctttgtatta ttgacaaact
     2761 cattaagctt ggaggtgcag aacgatgaca acttttgaaa aggttattag taagcttaat
     2821 cgaatcgagg gagaattagc taaacctgaa tctgaacgac gagataattc atatcacttg
     2881 tccgccctgt tgggttctat taaacaagat ttaaaattga tgctttggat tgagctgcct
     2941 tcgttaaata atgtggagaa atacgaagct ctttatcaag gaaatgattt taaattcagt
     3001 gaaactttct tagagcgtca agcgacaaga aaagcctttt ggagacgatt agctaaggaa
     3061 acttttaaag aagaccagga taggaggaac tttgttaagt tggctgagaa agaatttaaa
     3121 ggtgcaactt tgtcatggca agaatttttg tggggtaaaa agaaatgaat atttcaataa
     3181 aactcatagg tgaaacccta gctggtttaa atgatatttt acgccagggg ggctctcttg
     3241 ctcccaaaac caagccttag cagacgcagt ttttatatta acagctttaa aacaagtaat
     3301 tgaggagaga aaatgaacta cttagaatat gcactagttt atcttgaacg tgagttagaa
     3361 attattgata acgaagttat cgaagttgag ttgccgggcg gagattggga gtttgtgcct
     3421 aatccctact acgagaaagg tctacatgat agcccacact atcgtagtca ggttgctaaa
     3481 gacattcttg atattaaagg acttttgggg aggtgaggct attgattgca tcaaaaaaga
     3541 cggcttagga aaccgtcaac aattatacac aattaaatta taacacagaa agagagaaac
     3601 acaatgattg aagtaacttt taaagcagag agcatggcaa gtgttttcga tgctatgcgt
     3661 gaagctctgg atatgccgaa gacagcaacc gaggatgttg ttgaagaaaa atcagcccct
     3721 gaaaagaaag aagaatctgt aactttgaca ttagctgaca ttaagaaaat ggctaaagcc
     3781 aaggttgaag aagggaagtc aaaggacatc aaggaagtct tgaaagagat gaacgtcgca
     3841 aaagttggtg aacttgaaga ataccagttt gcggagtttg ttgagaagtt ggaggctctc
     3901 taatgccagt agaaaatcac gcactactgt ctgcttctag tgctcacaga tggctttatt
     3961 gccctatgct accgagatta gaagcagact atcctagccg cgacaccgta tacactcaag
     4021 agggcacaag cgcccacgag ctttctgaaa tcaaactgat gtacaagtct ggtaaaatca
     4081 ccaagcgtaa atttaacacg ttaaccaaga cttttaagga aaactcagac ttctacaacg
     4141 aagagatgga agagatgacg gagcgttaca cagatattgt tatggagcac ctaaatgctt
     4201 atgagaacgc cgaaattgaa cttgaaaaac gggttgattt tagcgactgg gttccgggcg
     4261 gttttgggac ttcggatgtc gtcattttgg ctgatggagt catggaaatt attgatctta
     4321 agtatggtaa gggcatgcct gtgtctgcta atcaaaaccc gcagatggga ctgtacgctc
     4381 taggagctta tgcttcctac gatatggtct atgactttga ccgtatcaag atgactatca
     4441 ttcagccgcg tttagattcg gttagttctg ttgacattta tgtagaggag cttctctatt
     4501 gggcggataa tattgtcttg cctatggccg ctcaagcaga cgcaggtatt ggcgactgga
     4561 acctaagtga aaaagtattg cagtggtctc ctgtcgcagc taaattggtg tcaagagcgc
     4621 aagaaaactg ggaattaatt gataaatatg actatcagga gcctgtctat ttatctgatg
     4681 aagccgtcgc agagatcctt gacaaagcct cagctatcaa gaagtgggtt gagtcagttg
     4741 aagcctatgc cctgaaagaa gcactctcag gaaaagaagt tccaggctat aagattgtcg
     4801 aaggtagaag taatcgagtt atcactgata aagacaaagc aattgatatt ttacaagata
     4861 acggctttga cgatgagatt tttaaaccga aagagctgtt agcaatggga gcccttgaaa
     4921 agttaatagg taaaaccact tttgctgatt tattagcaga agtaattgat aaaccacagg
     4981 gcaaacctgt acttgtccct gaaaaggata agcgcccagc aataaacagt ttagaacaag
     5041 caattaaaga ttttgaatag gagaaaaata attatgacaa caacaccaaa cacaactaaa
     5101 gtagtgaccg gaaaagtacg cctaagctat gtagctttac tagagcctaa agcctttgaa
     5161 ggccaagagg ctaagtattc aacagttatc ttaattccaa aaacagacaa agtcacaatc
     5221 aagaaaatta aagacgcgca gaaagctgct tatgaggctg ccaaggacaa taaactcaaa
     5281 ggggttaaat gggagcgcgt taagacaacg cttcgtgacg gtgacgaaga aatggatacc
     5341 gaagagcacc cagagtacgc tggtcacatg ttcatgtcaa tctcaagcaa aactaaaccg
     5401 cagatcattg acaagtataa aaactctgtt gattccgcag aagaagtcta ctctggcgtc
     5461 tatgctcgtg tatcacttaa tgcctatgct tacaacacag cgggaaataa agggatctct
     5521 tgcggattaa acaacgtcca aattgttgct aaaggagact accttggcgg acgttcgtca
     5581 gctgatgcag attttgacga gtggaacgaa gaagaggacg aagacgatat tttatagtag
     5641 agggcctctt tagaggctcc tcatttttaa aggagaggta tgagacattt aaatattgat
     5701 attgaaacct atagttcgaa tgacatcaaa aatggggttt acaagtacgc tgacgctgaa
     5761 gattttgaga ttttactttt cgcttactct atagatggcg gagaagtaga gtgccttgat
     5821 ttgacaaggc agtctctacc tgaagacatc aaagatatgt tatttgatga taaagtccga
     5881 aagcacgcct ttaatgccca attcgaaaga gtttgtctca gtcgttacct cggcctacct
     5941 tactatctag atccttgcca atggcaatgc accatggtgc tggcccaaga gttgggtctg
     6001 ccttcaagct tggaaaggtg tgcgctgtat ttaaaattag cacaggaaaa agatacctcg
     6061 ggtaaaaact taatcagata cttttccctg ccttgcaaac caagtaaaac taacggtggg
     6121 agaactagaa atttaccaga acacgccccc gaaaagtggc aaatgtttat tgactactgt
     6181 atccaagacg ttgttgttga gatggcaatc gccgaaaaac tagaatcagt tcctgtgcac
     6241 gaccgcgaat gggactacta cgcctgcgac cagagaatca acgacagagg cgtggcactt
     6301 gataaagagt tagttgcttc ggctttgtat tgtaaagatg ttaagatgga aagtttgtct
     6361 ggtgagctaa aagccataac aggacttgct aacccaaaca gtagagctca gctgctaccg
     6421 tggctaaaag aacacggtta ttcggctaac gggctgacta aagcagatgt tgaacaggaa
     6481 cttaagacgg ctgaaggaga acttaagaga gtcttagaac ttaaactaca aaccgctatg
     6541 tcaagcctaa aaaaatatga agctatggaa agagctatgt gctcagacgg acgagttcat
     6601 gggctacttc agttttacgg ggctagccgg acaggaagat gggcgggcag agttgtccaa
     6661 gtacagaatt tagctaggaa ttatataaag gatctagatg atgctagagg gtatgttaaa
     6721 aagcgtgata ttgatgctgt ggagatttta tacgatagcc ttaatgacac tttaaagcag
     6781 ctcgtgcgaa cggcactcgt ggctaaagat ggctgtacct tctatgtctc tgacttctcg
     6841 gcgattgagg ctagggtgat tgcatggttt gctggagagc agtggaggct tgacgtgttt
     6901 tcgacacacg ggaaaatcta cgaggcgtct gccagtcaga tgttcggaat tccaattgag
     6961 gagattgaca aggaactacg ccaaaagggc aaaatttcag agttagcact tggttatcaa
     7021 ggaggtcctg gagcgcttaa gcagatgggg gctctaaata tgggagtcaa ggaagaggag
     7081 cttcaagggt tagttgatga ctggcgcagg gccaataaga aaatcgtcca attttggaaa
     7141 gacgtacaaa gagccgccat caaagccatc aaatcgagag caccgataaa acttggaaaa
     7201 ctacgactta gataccggaa aggtttcctc tttataacat tgcctagcgg taggaactta
     7261 gcttatgcaa gagctaaggt tgagccaggc gactatggag acaaaatcat ctatgagggc
     7321 caaggagata aggcatactt cacagcgcaa gagacttatg gcggtaagct tgtcgaaaat
     7381 atcgttcagg cgacggctag ggatattcta gccgaagcgc ttctgagaat tgaagctgcg
     7441 ggccatggtg ttgttttcca cgttcatgat gaggctatta tcgaaggctc aggcctgaca
     7501 atcgaagagg ttaatgattt gatggctcaa gcgcctgact gggcggaggg tcttccttta
     7561 aatagcgaag gctacataac aaagtattat atgaaggatt agatagatga agcaagaaaa
     7621 actaatagta aagtcttctc ccctgcaaga gcttcatatc gcaacaggta gttcgcgaac
     7681 agctaagaca tggaaaaata tcacgctaac ttggcaggag ctggttgaga ggttagagaa
     7741 acctacagtc acccaagaga cgtttgcgga gtaccagaag atgtctcgag cagaaaaagg
     7801 gcaagcaaaa gacgtagggg gctttgtcgg tggatggcta aagcaaggta aacggaaaaa
     7861 tgaaaacgtt caaagtaggt ccttggttgc gcttgacgca gatagcccaa gtaaagattt
     7921 cttagatagg ctagacctgc ttgcggatta tgcctacgta ctctacagta ctcacagcca
     7981 ctcaaaaaaa gctgctaagt accgtcttat tatccctact gaccgtttaa tgatgcctga
     8041 tgaatatgag ccagtcgcta gatatttggc taatcaacta ggcatgtcaa actttgatga
     8101 cacgacttat caaagtgtac gcttgatgtt ctggccgagc cactcaagag atgcagactt
     8161 tacgtttaaa tataacgacg aggcttttct aagtgttgat gaggtgcttg atacgtaccc
     8221 cgactggcat gactcaagct tctggccaga aagcccgacg cacgctgtta aaagacagcg
     8281 tgaagctaaa aaacaaggtg acccgcttag taaaaaagga cttattggag ccttttgtcg
     8341 taactatgac attagacagg ccattgcaac attcttacct gaggtttatg aagaaggaac
     8401 gactcctgat aggtacacct acactgatgg ctcaaccgca aacggcttag ttatctatga
     8461 tgatgtcttc gcttatagcc atcacgggac agatcccgtg ggggatacgc ttgtaaatgc
     8521 atacgacctt gttcgtatcc ataaattcgg agagcaagat agcgaggcta aagataatac
     8581 tcctactaat aagctaccat caagcaaagc gatgaatgct tttgtctgtg acttacccga
     8641 aattaaagat tatctaatgg cggaggcttt aggcgatttc gatgaagagt taccagtcga
     8701 agatgacaga agctggcttg aaattgatga gaggggcgaa ccggaggtca atagttattt
     8761 gctagcaacg cagattatta aggaggttcc gatttattgg gatggcttag aatttttacg
     8821 ctacgacgct aaaaaaggca tctggttgcc aaacgctgag gaatatttga agagttatat
     8881 ctcaactaag aaactcggta aaattactaa gattaggcac attagcgaaa ccgtcgtagc
     8941 gattaaagca caggcttttt caagtgaagt gtttaccgag agtgatctta acaagatagt
     9001 gctagcgaat ggagtctatg acctgaggga taacagcttt aagactaagt ttgatccaga
     9061 attgcatgcc aggtcaagcc atcccgttgc ctatgccccc gaggcgacct gtgaaacctt
     9121 tgagggtttt cttagagaga ccgtcggagc tgaaaatata gatttcatct ttgagtggtt
     9181 tggctataac ttttatcgtg aatacactat tcaaaaaatg ctattcatct atggtagcgg
     9241 gggcactggc aaatcaacac taattaatat tttacgtgaa atgataggcg ctgataatta
     9301 ttcagccgtg acactgcagt acctgatgca agaacgcttt gcaaaaatcg gcttatatcg
     9361 taagacagcc aactttgaca ctgacgcaaa gccccaatat ttagcagatg gggctacgct
     9421 taaaatgttg actggggaag atacgataca cgctgaccgg aaaaacaaag agccgattaa
     9481 cttttacaat tatgctaagc tgtcttttgc catgaatgag ctcccaccta tgcgagattt
     9541 cagcggagga cttaagcgtc gcatgatgat ccttgagatg gataaagttt taacgcagga
     9601 ggttaaggca aaataccccc tagataagat tatgggcgag gtgcccggta tctttaacag
     9661 agcgatggag gggcttagaa aggccttaag taagagagat ttcagtatta gtgccagcat
     9721 gaggtcaagt gtcgagaaat gggaaaaagg caacgatgtc gtagctatgt tccttgaaga
     9781 cgagtgtgaa cttggcgaag acttcaaagt tcctgttagg gatgtctacc cagcctataa
     9841 attctattgt caggattcag gctacaaacc tttagctagg aattcgttta cgcaaaggat
     9901 gaatgagctg aattttgaaa ataagaacgc aaaaatgggg ggcaagaccg taagatgctg
     9961 gattggtttt aggctaaaag aagaatttta aagggttacg tttttcaaca aaaaaggtaa
    10021 acagaagata taaggttacg tagttacgca gaattcagac tgataaaaaa ttttataagt
    10081 tgaaaaaaaa cgtaactaca taactttctt gaaaaacctt tcctgtttaa gtcgatttac
    10141 ataactaacg ctacttttat gtaacctcaa aaaacctttc
//
LOCUS       DARYSY010000063         9799 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYSY010000063 DARYSY010000000
VERSION     DARYSY010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9799
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            56..1141
                     /locus_tag="TVR04_001677"
     CDS             56..1141
                     /locus_tag="TVR04_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1270351.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIRSILPSTAAKTIYVEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(1315..2898)
                     /locus_tag="TVR04_001678"
     CDS             complement(1315..2898)
                     /locus_tag="TVR04_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270352.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMIRAFNCLVAKKALYHFYHKQLNYSTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLSSITDFTKGVDTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVGPLIIGLLVMSYSSLSLTTLIAMMTASTNLVS
                     PLQQLLEATSSLQSATAIKEKMVRLLALEEETEHQALVPTDGLKLDVYFKKLHKHFDH
                     KLIFQGTDGHIPAGHKALLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLRLKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKKLVRCS"
     gene            3114..3965
                     /locus_tag="TVR04_001679"
     CDS             3114..3965
                     /locus_tag="TVR04_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270353.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKVAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQQQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFSLEYWTNLDVGLLGNIVHY
                     ITTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            4226..4894
                     /locus_tag="TVR04_001680"
     CDS             4226..4894
                     /locus_tag="TVR04_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1270354.1"
                     /translation="MSHKAIHQQLRNAFSFRAAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADNPRALFDWTAKQTYIALANMMTTAALM
                     GIDSCPIEGFDYDKVNAILAKHGIINPDTEGITSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            5009..5934
                     /locus_tag="TVR04_001681"
                     /pseudo
     CDS             5009..5934
                     /locus_tag="TVR04_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            complement(5918..6112)
                     /locus_tag="TVR04_001682"
     CDS             complement(5918..6112)
                     /locus_tag="TVR04_001682"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270355.1"
                     /translation="MVMTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQS
                     LSASLAADRGLDDCSVISFL"
     gene            complement(6218..6685)
                     /gene="smpB"
                     /locus_tag="TVR04_001683"
     CDS             complement(6218..6685)
                     /gene="smpB"
                     /locus_tag="TVR04_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1270356.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(6688..9012)
                     /gene="rnr"
                     /locus_tag="TVR04_001684"
     CDS             complement(6688..9012)
                     /gene="rnr"
                     /locus_tag="TVR04_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1270357.1"
                     /translation="MMIENITNYLKEHGQLNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRIQGIFRANKAGFGFLSVDDSEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKAAAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGSLRDIVGHQDDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDQQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDKEALQQ
                     FASIADDVSTMVELHQILEAMRVKRGALNFDTQEAKILVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAASSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVVASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFEYLASDYDVIEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRN"
     gene            complement(9099..9335)
                     /gene="secG"
                     /locus_tag="TVR04_001685"
     CDS             complement(9099..9335)
                     /gene="secG"
                     /locus_tag="TVR04_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1270358.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(9381..9527)
                     /gene="rpmG"
                     /locus_tag="TVR04_001686"
     CDS             complement(9381..9527)
                     /gene="rpmG"
                     /locus_tag="TVR04_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1270359.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
BASE COUNT         2943 a         2256 c         1852 g         2748 t
ORIGIN      
        1 gcttgctttt ttaagtattt tttggaaaaa tagaaggcag aaagaaggtt tatctatgac
       61 aaaattagat caaattcgtt tgtatcttaa tcaggaaaag gctgagcttg cgatcttttc
      121 tgattctgta acgatcaatt acttaactgg ttttttatgt gatcctcatg aaaggcagat
      181 gttcctattt gtctatcatg acaaggctcc tgtcttgttt gtaccagctt tagaggttgc
      241 aagggctgag caattgctgg acttccctgt ttttggctac gttgactctg aaaatccttg
      301 ggaaaagatc aggtctatcc taccaagtac agcagcaaag accatttacg ttgagtttga
      361 tcatttgaac attaccaagt ttcaagggct gcagagtgtt ttttcaggac gctttgacaa
      421 tctaacccct tacattcaaa gaatgcggct catcaagtct gctgacgaaa tccaaaaaat
      481 gctgattgct ggagaatttg ccgataaggc tgtcaatgtg ggctttgata atatttcact
      541 tgacgtcacc gagacagata tcatcgctca aatcgaattt gaaatgaaaa aacaaggcat
      601 cagcaagatg agctttgaaa cgatggtttt aactggtaac aacgctgcaa acccacatgg
      661 cattccagga accaataaaa tcgaaaacaa tgccctgctg ctctttgacc ttggtgttga
      721 aacattaggc tatactagcg acatgacgcg tacagttgcc gttggaaagc cagaccaatt
      781 taagctggat atttatcagc tttgcttaga ggctcagcta actgctcttg atatgattaa
      841 gccaggagtg actgcagctc aggtagatgc cgctgctcgc caagtgattg aaaaggctgg
      901 ctatggcgac tacttcaatc acaggctcgg ccatggtatc ggtatggacg ttcacgaatt
      961 tccatcaatc atggctggca atgacctgat tcttgaagaa ggcatgtgct tctcagttga
     1021 gcctggtatc tatatcccag gcaaggttgg ggttcgtatt gaggactgtg gtcacgtaac
     1081 taaagacggc tttgagctct tcacccaaac accaaaagaa ttactatact ttgaagggta
     1141 ataggaggct taaaaagcct gaaacaaaat gtctcagacc ctaatatcta aagcaacagc
     1201 acttggtctg ttgcttttca tattacaggc tattttctca caaggaaaag tcaaagcacc
     1261 ccttgatggg aaatcagagg ggcaaaagct atttgtacta agctcaaaag ctaatcaaga
     1321 gcacctgacc agctttttat cctttaagtg ataaatgcaa tcataagact gtgcattata
     1381 tttatgagct atctcaacca tggtgcaggg gagtgaatgg agtaactcac gaatctctct
     1441 ggcgctttct ttgtctaggg cagctgtgac ctcatcagcc agcaaaatcg gttttagtct
     1501 cagcaagcag cgtgcaattt ccagcttcat gatttgcccg ccagagagat tttgcccatc
     1561 tagatggaga tcaagatctc cgtttagctc attccaaaga tgaacctgct gtaatatctc
     1621 ctttagtcgc tggtccgaat aatcctgaaa cagcgtgaga ttatctcgca agcttccttc
     1681 aaatatgtaa ggcttttgat gtatcaaaga cacaacatca taggaaggaa aatagcgttt
     1741 tccattggca gcttcaaaat aaatagttcc agaataatcc ttatcctcac cacacaaaag
     1801 agcaaataaa gtggatttcc cactaccact ggctcctgtt agcaaggctt tatgccccgc
     1861 tggaatgtgg ccatctgtcc cctgaaaaat aagcttatga tcaaaatgct tatgtagctt
     1921 cttaaagtag acatcaagtt tgagaccatc tgtagggact aaggcttgat gttctgtttc
     1981 ttcctctaga gccaataacc taaccatctt ctctttgata gcggttgcag actgtaagct
     2041 cgaagtagct tctaataatt gctgcaaggg agagacaaga ttcgtagaag ctgtcatcat
     2101 agcaatgaga gttgttagtg atagacttga atagctcatc accaacagac caataataag
     2161 aggcccaacc aagccaatcc cttttaatgg accagtccaa aacattacca gattgtgggt
     2221 agtataatag ctatattgct tgtcttccat atgctgaatc atttctaaca catgatgagc
     2281 aaaagcttcg ttggcttgat tactctgtat cgtgtctacc cccttagtaa aatcagtaat
     2341 actggacaag cttttttccc tcgcctgact aagctccaag cctcgtgatt gaagtaagtg
     2401 attgaacaca aactgtggaa taatcatcaa aaagccacca atagtaaagg caataccaat
     2461 gtaaatatcc tgcaaaagaa ggtacaagac agaggctaat atagataggc caaaaacagg
     2521 ataaatgaat aaggggacca aatactcctg ccaaaacata ggaatatcct gtgtcaaaaa
     2581 cgaatttaag gctgaagtag agtagttgag ctgtttatga taaaaatgat ataaagcctt
     2641 ctttgcaaca aggcaattaa acgctctaat catagaacgt gctaaaatgt tattaagata
     2701 catgcacata taaataaaga caaaaaaagc cacacctcca agaccaaaaa gcaataccat
     2761 tcctttgttg ttcatatcaa tctgccctgc tatctgaatt aataccgata acaatagtcc
     2821 ctgcaaggaa tagagcaaag ccaataagct atacaagcag agctgccatt ttgaaatgac
     2881 ttgtaaaata cttttcatat caatcactcc tcacctgaat gctaaatgta ttgctctctt
     2941 ggaaagtatc aacgaagtca ccacaaacta gattcttgaa tgttaaatca agctcttgat
     3001 caaaatcatg ttctctgatt tcttgaacaa ccattggttc tctcctttca ttcttactat
     3061 ttctagtata taatggaaaa aaatacgaaa ggaaaaattt cggaaatccg gatatgaata
     3121 tcagagagaa atttaaagca attcgtaagc aaagaagact atccttaaaa acgcttggta
     3181 aggtagccgg ctcagctact agtatttctg acttcgaaaa tggaaaaacg aacctttcta
     3241 atgatgtttt attgcagctt ttaggcttta tgattgttga aataaacgag ctattcgaat
     3301 gggaggattt tcacgaaaag gaattggttg aagccatcaa gcaaatcgaa ctggcaataa
     3361 aatctaaaca tattcctgct ctatctcagc aacagcagga ctttcaaagc ttatctaaga
     3421 caaaggaaca gtacatttac cacatcatct cactgatcct aaccatcacc attgcagaat
     3481 atcaaaacaa agagatcgat ccacacatca tgtctgagct aacagactac ttcttttcct
     3541 tggagtattg gactaacctt gatgtcggcc tactaggaaa catcgtccac tacataacaa
     3601 cagatgccct aatcttattg acaaatgaca tcttagagca tacgcctcaa gtactccgaa
     3661 ataacctaga tcgtattagg atcgatactg tattaaactg tcttactgtc ttgattaatc
     3721 gtaaagagga gaaggcaagc agaacacttc ttaaattatt atttaacaaa cattatccta
     3781 attactttgc ctttgaaaag ctctatttac atgaattaca agcagtctat gattttaact
     3841 ggaaagataa agaacaggcg cttgcagctc atcacgtcat actggctacc atttcattac
     3901 tatttacagc tgatgaagcc aaagaatggg acagcttctt tcaagaaagt actagctctt
     3961 tgtaatactc cagctcatac actaaagaaa agcaaggata atcacataaa aactaatcac
     4021 atcactttgc cctgctagct gaattagctt gggtcatctc ttatgcccag caaaatatca
     4081 tctagtctca gctttcttcc aaagcttctt gtctctctgg gcttgcaagc ttttgatggc
     4141 ttaagaggca caagcatcaa caagggctaa caaatgcctg taaaaatatg ctatgatagg
     4201 ggtaacaaaa aactaggagg tgcttatgtc acacaaagcc attcatcaac agcttagaaa
     4261 tgctttttct tttcgggcag cggtacgcgt ctacaatgac caaaaaatag ccaaagaaga
     4321 cttagacctg attttagatg ctgcctggct cagtccttct tctatcggcc ttgaggcctg
     4381 gaggtttgtc gttttagaaa acgaagctgt caagcatgag ctaaaggagg tctcttgggg
     4441 agcagtttat cagtttgaga cagctagtca tatgatcctt ttaatcagcg aaaaaaacgc
     4501 cagatatgat ggcgcttcta tcaagcaaag cttattgcgc agaggcatta ctgacgagca
     4561 agccttggcc agtcgtctgg catgctacga agccttccaa aagcatgata tgaaaatagc
     4621 agataacccg cgcgcacttt ttgattggac tgccaagcaa acctatatcg cacttgctaa
     4681 tatgatgacc actgctgctc ttatggggat tgactcttgt ccgattgaag gctttgacta
     4741 tgacaaggta aatgctatcc tagcaaaaca tgggattatc aatcctgata ccgagggtat
     4801 tactagcatg ctgtctttag gctatcgcct gcgcgatccc aaacactcac aaaccagaaa
     4861 gcccagagaa gaggttattt ccttctttaa ctaagcccct tttgccattg ctcccaaaga
     4921 aagtgcaaag acagtccttt gccttttctt tttcataact ggtgaattat ggtacaatgt
     4981 gtcaaaagac ctgtggaaag tgatgcctat gacattatta tctgtaatta tcccctgctt
     5041 caacgaagaa gacacgatta ttccttatct tgaagaaatg aagcaaatcg aagcggccat
     5101 gaccagccaa ttagcctttg aatatctttt tattgatgat ggctctacag atcaaaccct
     5161 gagcgtgcta agagagcttg cggggcgctt ctctaatgtg cattacctct ccttttcacg
     5221 acattttggc aaggaagctg gactattagc cggcctagaa gagcaaaagg aagctatatt
     5281 acggtgatgg acgttgacct tcaagaccca ccagagctgc tccctctaat gtatagcaaa
     5341 ctacaagaag gctttgacgt ggtggccaca aaaagacaga gccgacaggg agagcctgct
     5401 atccgatcct tttttgctag gcttttttac aagctggtca agcatgtctc taacacagaa
     5461 atcgtcgatg gggtacgtga ttatcgttta atgacaagac aggtggtgga tagcatttta
     5521 gagctgggag aggtcaaccg cttttccaag gggatttttt cttgggttgg ctacaagact
     5581 gcctatatta gctttgacaa tcgcaagcgg cagtacggca aaaccagctg gaactttctt
     5641 gagcttttga actactcgat agacggcttt atcaattttt ctgagatgcc cttaaccatt
     5701 gctacctgga ctgggacact tagctttttg ctatctctgc tagccatttg ctttattgtg
     5761 atacgcaagc tgctttttgg tgatccggtt tcaggctggg caagcactgt atccattatg
     5821 ctatttatcg gtggaattca gctgttttgc atgggaatca ttggaaaata catttccaag
     5881 atcttccttg aaaccaagaa aagacccgtc tacatcatca aagaaaagaa ataacagagc
     5941 aatcatcaag gcccctatca gccgccaatg aggccgataa ggactggttg ccctcatcat
     6001 gacaagcacg acaaaaagac ttgatggtcc caatcaaaac catcaagtct tttttagtat
     6061 gtgaccttgc gtctgcctcg cacctaaaaa gacgagataa tgtcataacc accgtctatc
     6121 tactgacccc aaaaagttgg acaatttagt tttaagcaag ggatttagtt ctgtattgca
     6181 caggactaag caaggccatc agcttgtaaa cagacgctta gcggcggttc acactcttca
     6241 tcacacgccg aatgtcacga tcctgctcgc gtcgcttgat cgattcacgc ttgtcataat
     6301 catgctttcc tttggcaagg ccgattaaca ccttggcaaa gccatcctta agataaacct
     6361 ttagaggaac aagggtcatt cctgtgccct ttagctcatc tgctaggtgc tgaatctcac
     6421 gctttttgag caataatttg cgcgtgcgct ccggatcagc attccagata tttccctgct
     6481 caaagggagc aatatgaaca ttgaccaacc aggcctcacc attcttgatt tgggcaaagc
     6541 cgtccttgag ctggatacgt gcggcacgaa cactcttaat ctccgtaccg gtcaacacaa
     6601 ttccagcctc aactgtctca acgatatgat agtcatgacg agcctttttg tgttgcgcta
     6661 atacattacc ttcgcctttt gccatgctta attcctttta cgacctttct ttttagcagc
     6721 tttttggtaa aatggtttct ttgctttttt tcttgtcttc tgctttgatt ttggctttga
     6781 gggcttggac tccttgctcc tgctagccct tgaagcagcc ttttgcctgt gcttatgctt
     6841 agctttagct gaccttgtgg tcttttcaat cacatcatag tcactggcca agtattcaaa
     6901 atcaatgtca cctgtttcct tgtcagccct caccaatcta acccgaatcg gctgacctgc
     6961 tctaaatacc tttcctgagc gttcaccctt taaggagagt gtccgttcat tatagtgata
     7021 atattcaggc aaattggtaa tatgtaccag accttcaatt gtatttggca attcgacaaa
     7081 catgccaaac ttaaccacac tagcaaccac gccatcaaac acatcaccaa tatagtctgc
     7141 catgtattct gcttttttca tcgcctcaac cacacgctcc gcgtcaattg cacgacgctc
     7201 tagctgagag gacgatgccg ccaattctgg aataacctga gcaaaatgat ccaccttctc
     7261 ctgcgtgatc tgattgtatt ctcgaatcat gcggtgcacc agtaaatcag ggtaacgacg
     7321 aatcgggctg gtaaaatgcg tgtagtagtc tgctgctaag ccatagtgac catgattatg
     7381 ctcagaatac ctagcctgct gcatagagcg cagcagcatc atattcaaaa cctctgctcc
     7441 aggacttcct tctacctttg ccataaaggc ctgcaaggct tcttgagaaa tcttattagc
     7501 agttccctga atctgaatcc caaaggcact agcgtaatca ataaaggtct gcaatttctc
     7561 tgcctttggc tcctcatgaa cccggtaaat aaatggcaag ccagcccttg aaaaatgctc
     7621 agcaacacat tcatttgctg ccagcataaa ggactcaatc atgcgctctg caacacctcg
     7681 ctgacgcaaa accacatcaa ccggcatgcc cttatcattg acaaggatct tagcctcctg
     7741 cgtgtcaaag ttcaaggccc cacgcttcac gcgcatcgcc tctaatatct gatgcagctc
     7801 aaccatagta ctcacatcgt cagcaatcga ggcaaattgc tggagagcct ccttgtcacc
     7861 tgcaatcatc tgattgaccg cgctgtaggt cattctaaag gttgtgttaa tcactgactg
     7921 acacagctga taatcaacca catgcccctg ctgatcaatc tccatgatcg ccgactgggt
     7981 caaccggtca acctttggat tgagagagca gataccattt gacaaccgct ccggcagcat
     8041 tggcaccaca cgatctgtca cgtaaacaga ggttccgcgc gccgctgcct cacgatctaa
     8101 ggctgaccct tctgtcacat agtaggacac atctgcaatg tgaaccccaa gttcaacgtt
     8161 tccattggcc aatctcttga tatggatggc gtcatctagg tctttagcat cagcaccatc
     8221 aatagtgatg gtcgtttctt tgcgcaaatc aacacgcccc ataagatcct gatcactcgg
     8281 agcatcaggt atagcatttg cctcggctaa cacatcatct ggaaatgctg acacaatatc
     8341 catagactcc aaaacctcca gcacatcaat gccgacatca tcttggtgcc cgacaatatc
     8401 acgaagactt ccaacaaaat aatcctgccc agccttagga tattgcacaa tatcagcttt
     8461 aatgatttca gtaccatcta aggcaattgg agattttgcg atataaatcc tctgttgaat
     8521 cctttgattt ttcgacttga tatacccagc atacttaggg tgatcatcat ctaaaataac
     8581 cctaccaaca accgtcttta aagagcgctc cacgatagct accacgcggg cctctgctgc
     8641 tgcagcctta agacggttag ctggtttttt aataacagcc tcaaccctat cgccatcact
     8701 agcatacccc acatcatcgc gaccaataaa gatatcgtcc tcgctatcat caaccgacaa
     8761 aaagccaaag ccagccttat tggcacgaaa aataccctgg atccttatct ctggcttttt
     8821 ttgctgcggt gctctaagaa acacctcacc ctcatctgaa aaagacaaaa gtcccttgcc
     8881 ttccattttg gaaatggctt taatcagtcg aggaaagctc ctcgcatcag tcatctctag
     8941 agcagctgcc aaatcatgaa tatttaattg accatgctcc tttaaataat tcgtaatgtt
     9001 ctctatcatc atacctatct tctatttcta acaccatact tgatggttgt gctcattgat
     9061 aaaaaaatga gctagactaa ctctgtcaag ctcactcctt atttacttga taaaatggca
     9121 agcactaacg caattgctag ccaaaaaaac actagaactg ctgtaaaacg ttgcataaaa
     9181 gcttcaaatc cgcgagcttt tgtacgctca aacaaggctt ctgagccact gctatcaaaa
     9241 acattgctac taggattttt ttgtggctgc ataaagatag caatcacaag caacactgat
     9301 aatactagca atatcgtaag tagtaagtcg tacatgttaa ttcctccact gtagtctcaa
     9361 tcattctaac acaaaaccaa ctaagattca acatgcagcg ttacttttct ctccttagga
     9421 cagtatttag gaaccttaat cttctcaggg tgacttgttt tatttttact agtcaaataa
     9481 tttttgctgc cgcaatgact gcactccaaa tgaatcttta ctctcacatc atttccctaa
     9541 tcctaatatt tgttatcacc atcataaggc ttcaaatcac ccgcagcttc tttattaaag
     9601 atatctctag ttattatagc atattatcca gtaagaaaac aaactcagga cttttagcaa
     9661 aaaaaggctt aagcgccaac caataaacat tccaaggcta tcggggaata ttttttaatg
     9721 gttattagaa atcatgaaca attacctaac aaagcaatct aaaacaaaga taaaaaacga
     9781 acattcacct tgctgctca
//
LOCUS       DARYSY010000064         9672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYSY010000064 DARYSY010000000
VERSION     DARYSY010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9672
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..506
                     /locus_tag="TVR04_001687"
     CDS             <1..506
                     /locus_tag="TVR04_001687"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1270360.1"
                     /translation="PEKFDEDKYWITVDLYASNDKQVREFSHKLDDNISNQYYRVVLD
                     TKGSKYDFVYLPELQIIGYQLPAADLVMAMLATAEELSQQKDKFSQEQLKELETKVAA
                     LKASLDSKMFNADAINASAADLKAYVDKLLADRTNQEKAAKAAKVEQPVATDIKENTE
                     PENPKAD"
     gene            863..1747
                     /locus_tag="TVR04_001688"
     CDS             863..1747
                     /locus_tag="TVR04_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1270361.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDETLAIVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLAAAFAIP
                     FYVTTDVNSSAYGEVISRPDIDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYMM
                     LHSDDVANAFLGVCPFHQGCLEGMAAGPSLEARTGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEYMLARVQEAFTRLINGYLPVPDVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            1863..2807
                     /gene="manA"
                     /locus_tag="TVR04_001689"
     CDS             1863..2807
                     /gene="manA"
                     /locus_tag="TVR04_001689"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1270362.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSAVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            3185..5713
                     /gene="secA"
                     /locus_tag="TVR04_001690"
     CDS             3185..5713
                     /gene="secA"
                     /locus_tag="TVR04_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1270363.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERATQYATTTAA
                     QNIQSQAIGDDFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            5829..6185
                     /locus_tag="TVR04_001691"
     CDS             5829..6185
                     /locus_tag="TVR04_001691"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1270364.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            6182..7282
                     /locus_tag="TVR04_001692"
     CDS             6182..7282
                     /locus_tag="TVR04_001692"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1270365.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDNIHQHIPKKVKTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADESDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFSAIR
                     LGIVIYGLNPSGNSLSLPCSLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGERCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            7552..8967
                     /locus_tag="TVR04_001693"
     CDS             7552..8967
                     /locus_tag="TVR04_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1270366.1"
                     /translation="MRKDKLLRMVMLMTLLAPHLETARVLAEDTGAEVSQISATVNEA
                     VVAQTGESTSTTATTSGTDNSSSTPATTPNSGEPGATGSSSNTASSGAASSSTGQPTP
                     ASPEVSPQPASEAAAQGAQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            complement(9081..9263)
                     /locus_tag="TVR04_001694"
     CDS             complement(9081..9263)
                     /locus_tag="TVR04_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HEL1270367.1"
                     /translation="MTRISKYTQVLELTVEMVNELIDKIVIHKPTGTKRNRIIQIDIS
                     YNFIGKLTNEKASQAD"
BASE COUNT         2765 a         1820 c         2358 g         2729 t
ORIGIN      
        1 aaccagaaaa atttgatgaa gataagtatt ggatcacagt agatttgtat gcttcaaatg
       61 ataagcaagt cagagaattc agtcataaat tagatgataa tatatctaat caatattatc
      121 gagtagtttt ggatactaag ggtagtaaat atgattttgt ttacctccct gagcttcaaa
      181 tcattggtta tcaattaccg gctgcggatc ttgtgatggc aatgctagct actgcagagg
      241 agctatctca gcaaaaagac aagttctctc aagagcagct taaggagctc gaaaccaaag
      301 tagctgccct caaggcttct ctagatagca agatgtttaa tgccgatgct attaacgcta
      361 gtgctgctga tctgaaggcc tatgttgata agcttttagc tgatagaact aatcaggaaa
      421 aagcagctaa agcagctaaa gttgagcagc ctgtggctac tgacataaaa gaaaatactg
      481 agccagaaaa tccaaaggca gactagctta tccttgagca agctgtcgct cttggttatt
      541 agcttgaggt tactgatcat tatgttaaca cattaagctt tagagataag gcgatgaaca
      601 caccattaaa agcaattgtt tgtgctgctt cttagtggca gctcctgctg ccaaggcttc
      661 cctcctaaaa tcaattgcct tatctcttaa aggcatatca aaaatctgag atagtcctat
      721 cccagatttt tggtctttta taggaggcaa ggaagcaagc gatgatgttt agttactaag
      781 gtagctgctg attagctggt gtgattttga gccttgtgag aataaccagc acagggctta
      841 tcactattat taaggagaaa agatgaaaac attacttgga agtattgaag caggcgggac
      901 aaagtttgtc tgtgctgttg gagatgagac tcttgcaatt gtggataagg tgcaatttcc
      961 aacgacaagc ccaaaagaga ccattgagcg tacgattgct tattttaagc aatttgaggc
     1021 cgacttggct agtattgcta ttggctcctt tggaccgatt gacattgatc ctaagtcagc
     1081 tacctatggc tatattacca caacaccaaa gcctggctgg gcaaatgtag atctgttagg
     1141 gcagctagca gcagcctttg caattccttt ttatgtgaca actgatgtta atagctctgc
     1201 ttatggagag gtcatctctc ggcctgatat tgatagtctt gtgtattata cgattggaac
     1261 gggtattggt gctggagcca ttcaaaaagg cgagtttatc ggtgggctag gtcatacaga
     1321 ggcgggacat acctatatga tgttacactc tgatgatgtg gcgaatgcat ttttgggcgt
     1381 ttgtcccttt catcagggct gtttagaggg catggcagca ggtccaagcc ttgaagcaag
     1441 gacagggatt aagggtgagc tccttgatca gaaggcagct gtttgggata ttcaggcctt
     1501 ctatattgct caggctgctg tacaggcaac gctgctttat cgacctcagg ttattgtgtt
     1561 tggtggcggc gtgatggcac aggagtacat gttggcgcgt gttcaggagg cgtttaccag
     1621 actgattaat ggttatttac cagtacctga tgttagagaa tatttggtca caccagcagt
     1681 tgcaggtaat ggctcagcca ctcttgggaa ttttgcctta gcaaagctga ttgctgaaaa
     1741 gagctagata cttgagctta tctgataaaa gtcctagagt catttgcaaa atgtgcctga
     1801 aattggtaga attggggcaa agaatgtcac cataggttag tgaaaagaga atgaggatta
     1861 ctatgtcaga accattattt ttaacatcat gcatgcatga taagatctgg ggcggaacaa
     1921 agctaagaga ggtgtttggg tatgagcttc caaccgaaac cactggggag tattgggcaa
     1981 tctcagctca ccctaatggt gtttccgcag ttagcagtgg tagctaccaa ggccaaaggc
     2041 tagatcagct ttatgcagaa agaccagagc tatttggaaa tccaaaggaa aaggtctttc
     2101 cgctgttgac gaagatttta gatgctaatg actggctaag cgttcaggta cacccagatg
     2161 atgcttatgg gctggcccat gagggagagc taggaaagac ggaatgctgg tatattattt
     2221 cagctgaaga aggcgctgag attgtttatg gtcatcatgc aagctctaaa caagagcttc
     2281 gtgcgatgat tgaggcgggg aactgggaag agttgttgac gcgagttcca gttaaggctg
     2341 gtgatttctt ctatgttcca agcggcacga tgcatgccat tggtaaggga attttgatct
     2401 tagagacgca gcaatcctca gacacgacct atcgcgttta tgattttgat cgtcgagacg
     2461 ctgaaggtca gcttcgtgag ctccatattg agaaatctat cgatgtccta actattggca
     2521 agcctgagaa cagcacgcca gccacactag aacttgagca cttggtctct acctgcttag
     2581 tatctaatcc cttctttaca gtttataaat gggagattga tcaagcagtc agcatgaagc
     2641 aatcagcccc ttacctgctt gtcagtgtgc tggctggtca gggaagcctt acgattgatc
     2701 aagctgttta cgagcttcaa aagggtatgc attttatcct gccaaatgat gtgacgtcat
     2761 ggagctttga tggtcagctg gaaatgattg tcagtcaccc taattaagca cagaatacac
     2821 gaaaacacca agaaagactg tttggacaag cggcctttct ttttctgata tcttatcaca
     2881 acagacgcat gaagaaaaaa tttccaagat atttctgaaa tgcgaaaatt tattctgaaa
     2941 aataggaaag ccatagcgat agttgtagaa aagaaatttt tcaagaaaag tttatagagg
     3001 gagaatataa caattcagga aacactctgt caaaataccc taaaatggct attttgctat
     3061 tttcacaact ttttcaataa atgattttct tcatgtgtct gtcatggata tcttatgatc
     3121 atttcttgaa ctgcctgcct atttatgtta gaataaaatg attagtcgat cgaaaggaaa
     3181 gagaatgagc aatattctac gcaaagtcat tgaaaatgat aaaggcgaat tacgaaaatt
     3241 agaaaaaatt gcgaaaaaag tagagtccta tgctgactat atggagtcct tgtcagataa
     3301 agacctacaa gcaaaaacgc ccgaatttaa acaacgttat caaaatgggg aaacccttga
     3361 gcagttatta ccagaagcat ttgcggttgt ccgcgaggcg gctagacgtg tgctgggact
     3421 ttacccttat cgtgttcaga tcatgggggg aattgtcttg cacaatggag atgtccctga
     3481 gatgcgtacc ggtgaaggta agacccttac agcgaccatg cctgtttacc ttaatgccct
     3541 tgctggcgaa ggggtacacg ttatcactgt taacgaatac ctgtcaactc gtgacgcaac
     3601 agagatggga gaggtttata gctggctagg actttcagtc ggtatcaacc tagcagctaa
     3661 atcaccagct gaaaagcgtg aggcttatct atgtgacatt acctactcaa ccaactctga
     3721 ggtgggcttt gactacctgc gtgataacat ggtggttcgt caagaggaca tggttcaacg
     3781 accattgaac tttgccttgg tcgatgaggt tgactctgtt ttgattgacg aggcaagaac
     3841 gcctctgatt gtctctggtg ctgtgagctc agaaacgaat cagctctata ttcgtgcaga
     3901 catgtttgtc aaaaccttgg attcagttga ttacatcatt gatgttccga ccaagacgat
     3961 tggcctaagc gactcaggta ttgataaggc tgaaagctac ttcaacctca gcaacctata
     4021 tgacattgaa aatgtggcct tgacccactt cgtggataat gcccttcgtg ctaactatat
     4081 catgctttta gatattgatt acgtggttag cgaggaaggc gagattttga ttgtagacca
     4141 gtttacaggt cgtacaatgg agggacgacg cttttcagat ggcttacacc aagctattga
     4201 ggcgaaagaa ggcgttcgta ttcaagagga atcaaaaaca agtgcctcta ttacctacca
     4261 aaacatgttc cgtatgtata agaaattggc gggtatgact ggtacagcaa aaacagagga
     4321 agaggaattc cgcgaggttt acaacatgcg tattattccg attccaacca atcgacctat
     4381 tgctcgtatt gatcacacag accttcttta tgcaacgctg aattcaaaat tcaaggcagt
     4441 ggttgcagat gttaaggctc gctatgaaaa agggcagccc gttctagttg gtacagttgc
     4501 tgttgaaacc agtgacctga tttctaaaaa gctagtagaa gcaggcattc cgcatgaggt
     4561 cttaaatgct aagaaccact ttaaagaagc acagatcatt atgaatgctg gtcagcgtgg
     4621 tgcggtaacg attgcgacca atatggctgg tcgtgggaca gacattaagc tcggtgaggg
     4681 tgtccgagag ctcggtgggc tttgtgttat cgggacagag cgtcatgaga gccgccgtat
     4741 tgataatcag cttcgtgggc gttcaggtcg tcagggagat ccaggggagt cacaattcta
     4801 cctctcttta gaggacgagc tgatgaggcg ctttggtaca gaccgtatta aggctttctt
     4861 ggatcgtatg aacaatgatg acgaggatat tgttatcaag tccagaatgc tgtcacgtca
     4921 ggtggagtca gctcaaaaac gtgttgaggg taataactat gacacacgta agcaggtctt
     4981 gcagtatgat gatgtgatgc gtgagcagcg tgagattatt tacgctaacc gtcgtgatgt
     5041 tatcacagca aatcgtgacc taggtcctga aattaaggca atgatcaagc gtacgattga
     5101 tcgagcagtt gatgcccact cacgtaccaa tcgtaaggac gctattgacg ccatcgtgac
     5161 ttttgcgaga acatcaattg tcccagagga aaccatcggt gctaaggaat tgcgtggcct
     5221 caaggacgat cagatcaaag acaagctcta tcagcgtgcc cttgagattt acgataagca
     5281 gttatcaaaa ttgcgcgatc aggacgctat cttggaattc caaaaggtgc tgattttgat
     5341 gattgttgac aacaaatgga cagagcatat tgatgcctta gaccagcttc gtaatgcggt
     5401 tggtttgcgt ggttatgcgc aaaataatcc agttgttgaa tatcaaagtg aaggcttcaa
     5461 gatgttccag gatatgattg gtgctatcga atttgatgtc acacgtacca tgatgaaggc
     5521 acagattcat gagcaggagc gcgagcgtgc aactcagtat gcaacaacaa ctgcagcaca
     5581 aaacattcag tcgcaggcta tcggtgatga ttttgattca tcagctgatt tttcaagagt
     5641 cgagcgcaat gatgcttgtc cttgtcactc tggtaagaag tttaaaaact gtcatggtcg
     5701 taaggctttt taaggatagc gtgatggcca tgttgaaaac ctgtgaggag ctgagatttg
     5761 ttctcggctt ctccttgttt aggatttgtt tccctaaatt aaagtgaagg ctggtaaaat
     5821 aaaggcaaat gattgttgga catgggatag atttacagga tatttcagct attgaaaagg
     5881 tttatttgag aaatgctaga tttgctagaa aggttttgac ggacaaggag ctagcgctgt
     5941 ttgagcaatt ttcccatcac cgaaaaatga cctatctggc cggccgctgg gctggtaagg
     6001 aggccttttc aaaggcaatg gggacaggga ttggtcagct aacctttcag gatattgaaa
     6061 ttatcaatga cagcaaaggg cgtcccgtca ttacaaaatc tccctttcag gggaaggcct
     6121 ttatcagtat ttcacatagt gggggctatg ttcaagcaag tgttattttg gaggatttag
     6181 catgatttca agcttacatc gaccaacagt agctagagtt gacttagaag ctattcgagc
     6241 aaatattgac aatattcatc agcatattcc taaaaaggta aagacatatg ctgtcgtcaa
     6301 ggccaatgct tatggtcatg gtgcagttgc ggtgtcaaag gcagttgaag atcaggttga
     6361 tggctattgc gtatcaaacc ttgatgaagc cttggaatta cgtcaggcag gcattgataa
     6421 ggaaatcctg attttagggg tgattttagc aagtgaattg cagctagcca ttaagcatca
     6481 gctgacgata acggtggcca gcttagagtg gctagagctt gccaaaaagg aatcggttga
     6541 tttcagtcag cttcatgtgc atgtcaaggt tgactcggga atggggcgca ttggtgtcag
     6601 gtcgcttgct gaggccaatc agctcatctc aatcttatcc gatatgggag tgcagcttga
     6661 cgggattttc acgcattttg caaccgcaga tgagtctgac catgccatgt ttgataagca
     6721 gctgaccttt ttcaagcagt tggtggagca gctagataag aggcctgcat tagtgcatgc
     6781 aagcaattct gcaacaagcc tttggcatag tgaaacaatt tttagtgcca ttcgccttgg
     6841 gattgttatc tatgggctca atccaagcgg caatagcttg agcctgcctt gttccttaaa
     6901 ggaagccttg tccttagaat cacgtttggt tcatgtgaag caaattcagg caggggatag
     6961 cgttggctat ggagctagct atgtagcagc agagccagag tatgtcggga ccttacctat
     7021 cggctatgct gacggttgga ctcgaaatat gcagggcttt aaggtattgg tagaagggga
     7081 acgttgtgat attattggtc gtgtgtcgat ggatcaattg actattcgtt tacctaaagc
     7141 ctatcctatc ggcactaagg tgaccttgat tggacagcag ggtaaacaag taatcacagc
     7201 aaccgatgtt gccgattata gaggtacgat taattatgag gtgctttgct tgctgagtga
     7261 tcgtattcct agagaatatt aggaaattga gcctaggctc aactattgac tggcctcaag
     7321 gctgtttttc aaatgattag tcctgtaaag gtcttgagat ctcaggctaa tagcgtgaat
     7381 aaggtagatt aaggcaggtc ttgtttttct gccggttaag aaaaagaata aggaaaggct
     7441 cttaccttta tctgagtatt aaggcattaa tacaaaaaat cttgcatttt attttgcttc
     7501 aatgttataa tgtaggttag aatagagcag aaagaagtga ttgaatacta aatgagaaaa
     7561 gataaattat taagaatggt aatgctgatg actcttctgg cacctcattt agagactgca
     7621 agagtattgg cagaggatac aggagctgaa gtcagccaga tttcagctac tgttaatgag
     7681 gccgtagttg cccagactgg tgagtctact tcgacaacag ctaccacctc aggtactgat
     7741 aattcctcat caacccctgc gactactccc aacagtggag aacctggagc aacggggtca
     7801 tcaagcaata cagctagctc tggagcagct tctagttcta ctggacagcc gactcctgct
     7861 agtccagaag ttagccctca gccagcctct gaagcggctg cacagggagc tcagccggcg
     7921 ctgaatattg ttcctgctgc tcctacagtt gatttgtcct tgactctggc cctaccttct
     7981 gtaaatacct atgctgctta tgtgacgcat tggagtggtc agagtgctta tacccataac
     8041 ctcttgtcta ggcgctatgg gatcaaggca gagcagcttg atagcttttt aaagtctacc
     8101 aagatcaagt atgatgagaa gcgaattaac ggtgctgcct tgctgcaatg ggaaaaaaag
     8161 agtgggctag atgtgcgggc gattgtagcc attgcaatga cagaaagtga gctaggaacc
     8221 aagggaaatg caaccttact aggctctaac atgtttggct atgcgctttt tgaccttgat
     8281 tcgaaaaagc caaatcagtt taatgatgag cttgctattg ttaagctgac acaggagacg
     8341 attatcaaaa atagcaacct taattttgag cagcaggatc aaaaggctga taaatttgcc
     8401 aaaaagcagt tgaactttgc tagtgatggt ggtctttact tcacagatac caatggcatt
     8461 ggcaagcgtc gcgctgagat catggaaaaa ttagacgctt ggattgatca gcatggaggc
     8521 acgccagaga ttccggctga gctgaaaatt caatcctctt caagctttgc tgttgttcct
     8581 acaggctaca agctgtctaa gagctatgat attttaagct atcaggcgtc aagctatgct
     8641 tggggacaat gtacctggta tgtttataat cgcgctaagg agctaggcta tcagtttgat
     8701 tcctttatgg gaaatggtgg tgactggaga tttaagtctg gctacagtat ttctaaggag
     8761 ccaaaggtag gctatgcggt ttcctttgct ccaggtcaag cgggtgctga cggtctttat
     8821 gggcacgtct ctattgttga ggatgtcaga aaggacggct ccatcctgat ttcagagtca
     8881 aattgtcttg gcttaggtca gatttcatac cgcaccttta ctgctgagca ggccaaccaa
     8941 ttgacttatg ttgttggaaa atcataagta atcttcttgc tttaaaggcg agaagtacag
     9001 aatttttgta agaaaaaatc cagctctgtt agccaagctg acaccgagca gtttagttat
     9061 taggggttaa tagcagcgag tcagtccgcc tgactcgctt tttcgttggt tagttttccg
     9121 atgaaattgt aagaaatgtc tatctggata attcggttgc gtttcgtgcc agttggcttg
     9181 tgaatcacaa tcttgtcaat cagttcattt accatttcaa cggttaattc taaaacttgt
     9241 gtatatttag aaattctcgt cataaactta gagatattca agctatcttc ttgttgtttg
     9301 gctagctttt ctgttaagtc agaaatggaa gttcgaagtc tcctgccgaa tgagttagac
     9361 cgacaaatcc atagtatttc atgtgataga ctaggcttaa aaggctcgtt ttacggagat
     9421 gaaaaaattc tattcatcga cacgattcga agaccgattg gaacgagctt cattacaaat
     9481 aatatagtag tctcaactaa gaaatgaaaa ctacagtatc ttgaaagaat taattttgtg
     9541 agcgaaatat aatttaacga aatatttccc ggggtatttt agttggcgcg ttttaaaagc
     9601 tgtttaaagc tatactctgt ctcgcgctat ctctacgata tggtataata aaagaagcgg
     9661 tagtctgagt ta
//
LOCUS       DARYSY010000065         9325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYSY010000065 DARYSY010000000
VERSION     DARYSY010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9325
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            300..1010
                     /locus_tag="TVR04_001695"
     CDS             300..1010
                     /locus_tag="TVR04_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1270368.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQAFRAYPTVADSLYDYANLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDMVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            1223..1603
                     /locus_tag="TVR04_001696"
     CDS             1223..1603
                     /locus_tag="TVR04_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1270369.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            1603..2451
                     /locus_tag="TVR04_001697"
     CDS             1603..2451
                     /locus_tag="TVR04_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1270370.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGKSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSAEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMGKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTDSGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            2555..3766
                     /locus_tag="TVR04_001698"
     CDS             2555..3766
                     /locus_tag="TVR04_001698"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1270371.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFPRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIETETFEAMKSHAPLLEKISVERSFIELDKLLMAPKWRKGIL
                     AMIACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQRDHI
                     EAFVRRELLNE"
     gene            3759..5627
                     /locus_tag="TVR04_001699"
     CDS             3759..5627
                     /locus_tag="TVR04_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1270372.1"
                     /translation="MSDFIVEHLTKSVGDKTVFQDISFIIHAGDRIGIIGVNGTGKTT
                     LLDVISEKVGFDGDRSPFSKANDYRISYLTQEPDFDDDQSVLDTVLSLELKEMQLIRQ
                     YELLMADYSDSNQEKLAEVMTEMDRLDVWSIESEVKTVLSKLGIVNLDQRVGDLSGGM
                     RRRVQLAQVLLGASDLLLLDEPTNHLDIDTIAWLSHYLRTSKRTVLFITHDRYFLDSI
                     ATRIFELDKAHVTEYQGNYQDYVRLKAEQDEREAAHLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFEQLKKDLHQERPIDQLDMAFEASRIGKKVINFKEVSFAYGDQAIIEH
                     FNLIIQNKDRIGIVGANGAGKTTLLSLMTGDLKPTAGQLEIGETIRIGYFSQQIKDMD
                     GSKRVISYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGSLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLEHFLAQFAGPVITVSHDRYFLDKVATKVLAFE
                     HGAIREYYGNYSDYLDEKAFEAEVIEPAVSEQKAGTDHQVTSKKRMSYLEKKEWAAIE
                     EKLAAIEQQIATIEEQMLGAASDYDQLAQYQKELDQRNLELLEAYERFDYLSELEE"
     gene            5732..7477
                     /locus_tag="TVR04_001700"
     CDS             5732..7477
                     /locus_tag="TVR04_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270373.1"
                     /translation="MALIWSYLKTRPKWICLDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFVIVLLGVVGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAVKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITASTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLASNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            7477..9249
                     /locus_tag="TVR04_001701"
     CDS             7477..9249
                     /locus_tag="TVR04_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270374.1"
                     /translation="MTEKHVFRRIWTYLSAYRLSLITAITLKIVSAVMSVLEPFVLGL
                     VITELSANLLDIAKGVSGAGINKPYIAFLLVLYIIRALVYELGSYGSNYFMTKAVQSG
                     IRDLRRDLSQKINRIPVSYFDKHQFGDMLGRFTSDVETVSNALQQSFLQIVNAFFTLI
                     LVVGMVLYINAPLASVVIIAIPLIYAASRFVLKKSQPYFKAQANILGEMNGFVQENLT
                     GFNILKLYGREEASKEEFHQITERLQEVGFKASFISGIMMPVLHFISDSVYMIVALIA
                     GLQVIAGRLTIGNMQAFVQYIWQISQPIQTITQLAGPLQSAKSSLERIFAVLDEADEL
                     TIAQEHLEHDLTGQVSFNQVDFSYTADNPLIRNFNLEVKPGEMIAIVGPTGAGKTTLI
                     NLLMRFYDVNKGSITVDGQDIRQLSRQAYRRQFGMVLQDAWLFEGSIQENLRFGNLEA
                     TDEQIIEAAKAANVDHFIRTLPGGYHMVMNQESSNISLGQKQLLTIARALLADPKLLI
                     LDEATSSVDTRLELLIQKAMKRLMVGRTSFVIAHRLSTIQEADKILVLKDGQIIEQGN
                     HDSLLAAKGFYYELYHSQFKATQS"
BASE COUNT         2663 a         1661 c         2212 g         2789 t
ORIGIN      
        1 ttttctttac ctaaaaaata aaggcagtta aatggaaaat acttaacaga caggcataaa
       61 gaacaatagt aggtgtaata acctttcaaa ggtattgaag ctattacaag gcgatatagc
      121 aaataaggcg taaaagatta tgaaaagcct tcgctttatg gacttggtaa gccttcttta
      181 cattaaaata tttcgattta aagacaaaag ttatcaatat gattaaattg tttgtggata
      241 agtcttttta tgagcattct gtgctataat ctatttatca aaaaaagagg gaatgataaa
      301 tggcaaaaaa gaaaggtaag ctcacactta tcagtctttt tgttctagta gcctgcttag
      361 gtgtttatag ttcaattaga cagtcagaaa atacatcaga tgtctcagca gagactgtgt
      421 caacgtcgtc aacgcaagcc tttattgaag agattggagc aactgctagt gttgttgctc
      481 aagaaagaga cttgtatgct tcggttatga ttgctcaagc tattttagag tcagctaacg
      541 gtaaatcagc tttaagtcaa gcaccttatt ataatttttt tggcattaaa ggggcttata
      601 atgggtcatc agtgacgatg acaacatggg aagacgatgg ggctggaaat acttactata
      661 tcgaccaagc ctttagagct tatccgacag ttgctgattc cttatatgat tacgctaatt
      721 tgcttagctc agatatttat gcaggtgcta gaaagtcaaa taccttgtct tatcaggacg
      781 ctacagcagc cctaacaggc ttgtatgcta cagatactag ctataactgg aaattaaaca
      841 acatcattga gacctacggt ctaacggcct atgatatggt aaataatcag gcgcaagaag
      901 cgcttgctgc ggctcctttg acctctgtct ggaatcctta tcgcaagagc tatacagaca
      961 ctgaaaccct tgctattgat aaggcatggg cacaacgaat gggctactaa agaatagaaa
     1021 aatgacttag cactccaagg cttgagttct agccttgggg tgttttttgt tgtaggagat
     1081 tggttggttg atagaaagca ggctgattta ttgaagtgac aaggtctgga aaaaattatc
     1141 caaaatactg gtttaagtct actttaatat tcgtcaaatc tatgctataa tgggtcatat
     1201 cgccattaag gagaacgaaa tcatgcaatt agtacgtgaa aaagaatttg tcaatcagta
     1261 ccattatgac gccagaaatt tagaatggga aaaagaaaat ggaacaccgg aaacaaactt
     1321 tgaagtaacc tttcagttga ttaataaaga tgtggaaaat aaagagacgg ctattgtttc
     1381 tgttttacaa tttgtcattg tcaaggaaga gtttgtgatt agtggtgtga tttcacagat
     1441 ggttcgtatt ttaggacgct tggtggataa gcctagtgaa tttacacaag aggaggtcga
     1501 atccttggct gctccattat tagacatggt gaagcgcttg acctacgaag tgacagaaat
     1561 tgccttggat cgtcctggta ttaatttgga gtttaaaagt taatgaagtt agcaataata
     1621 actgataata cagctcacct tccagagcag ttagcggagc atgccgatat ttttgtatta
     1681 gacatacctg taatcattga tggcaaaagc tatgtcgaag ggcagaacct gaccattgaa
     1741 gccttttacc aaagcatgag agaatctcaa gagctaccta aaaccagtca gcccagtctt
     1801 tctgaattag atgatctact aggtcgtctg tctgctgagc actatactca tgtgattggc
     1861 ttgttcttgg ctagtggtat ttcaggattt tggcaaaata ttcaatttct tatcgaagag
     1921 caccctgagt tgaccattgc ttttccagat agtaaaatca cctcagcacc gttaggcagc
     1981 atggttagaa atgctttaga gtggtctcag cagggcttga gctttgcaga gattatgggt
     2041 aagctagaag agcaaatcgc tggaaccaca gcctttatca tggttgatga tttgaatcat
     2101 ttggtcaagg gaggacgctt atcaaatggt tctgctttgc tgggaaattt gcttagcatc
     2161 aagccaattc ttcgctttga tagtgaagga aagattgtcg tctatgaaaa ggttagaacg
     2221 gaaaaaaagg ccatgaagcg cttggttgat atcttaaagg aattgacaga tagtggtcag
     2281 tacgaggtat caattatcca tgctagagcg caggataagg ctgatatctt aaagcagctc
     2341 ttgttggata atggctatac ctgccctgtt gaggaggttc attttggtgc agtcattgca
     2401 gcccatcttg gagaaggagc agttgctttt ggcataacgc ctcttgtcta aagggggcga
     2461 cttgcccatt accaagctga gcttgatatg acagccctta acgagaagca tatgacaagg
     2521 ctctaagagc ctttaggtgg tagattagaa catgataaca ttaatgacaa tgccttctga
     2581 atttcagaag gctttaccaa tagtgaaaaa aatcaagcag gctggctttg aggcctattt
     2641 tgttggtgga agtgtgaggg atagcttatt aaacaggccg attcatgatg ttgatatagc
     2701 tgccagctgc tatcccgagg agacaaaggc tattttccca agaacgattg atgttgggat
     2761 tgagcatggc acagtgcttg ttttagaaaa tggcagtgaa tatgagatca caacgtttcg
     2821 aactgaggac gtttatgtgg attataggcg tcctagtcag gtatcctttg ttcggtcctt
     2881 ggaagaggat ttaaaacgaa gggattttac tgtcaatgct cttgccttag atgaggacgg
     2941 acaggttatt gatatcttta atggcttaga ggacctaaag cataagcttc taagagctgt
     3001 tggaaggcct caggagcgct ttgaggagga tgccctgcgg attatgcgag gctttcggtt
     3061 tgctgccagc ttagattttg atattgagac tgagaccttt gaagcgatga aaagccacgc
     3121 tcccttgcta gagaagattt ctgttgagcg ctcttttatt gagcttgata agcttttaat
     3181 ggctcctaaa tggcgtaaag gtatcttagc tatgatagcg tgtcaggcct ttaactattt
     3241 gccaggctta gtgggcaagg aagaagccct gcaaaagtac ctgaaaacct tagcagcgga
     3301 ttatgtgttt caggacaatc atcaggcttg ggcttatttg ctggttatgc tggagcttga
     3361 tcagcctaaa gcctttttaa aggcttggaa aacctctaat gattttcagc gtagggttac
     3421 gatgatggcc tctctttatc agattcgcca agaaagacag ctagaaaaat gggatattta
     3481 ctcgtttggc aaggacttgg ctttactcgt tgacgattta cgacaggcac agggcttggt
     3541 cagtgaggcc aagcgtgttg agagcttgta tcaggagctg acgatccatg ataagcatga
     3601 tattgtggtc aatggctctt atctgattcg tgagcttgga atgaagccag gaccacagct
     3661 gggaatgctt ttaaatcaga ttgagcaggc cattgtagag gggcgtctcg tcaatcaaag
     3721 agatcatatt gaggcttttg ttagaaggga actactaaat gagtgatttt atcgttgaac
     3781 atctgacaaa gtctgttgga gataagaccg tttttcagga tatttccttt attattcatg
     3841 ctggtgatcg cattggcatt attggtgtca atgggacagg aaaaacaacg ctgcttgatg
     3901 ttatttctga aaaggtaggc tttgatggtg accgctcacc tttttcaaag gcaaatgact
     3961 atcgtatatc ttatttaaca caggagccgg actttgatga tgatcagtct gttttagata
     4021 ctgttctttc cttagaatta aaggaaatgc agctgattcg ccaatatgag ctgttgatgg
     4081 ctgactattc agatagcaat caggaaaagc tagcagaggt gatgactgag atggatcgat
     4141 tagatgtttg gtcgatcgaa agtgaggtta agacggtctt atcaaagctt ggtattgtta
     4201 atctggatca gagagtgggt gacctgtccg gaggtatgag acgccgagta caactggctc
     4261 aggtcttgct tggggccagt gatttgttgc tgctagatga gccgaccaat catttggata
     4321 ttgataccat cgcttggtta agccattatt taaggacctc taaaagaact gttctgttta
     4381 ttacacatga tcgctatttt ttggatagta tagccacacg tatctttgaa ttggataagg
     4441 ctcatgtgac tgaatatcag ggcaattacc aggattatgt gcgtctgaag gctgagcaag
     4501 acgagcgcga agcagctcat ttgcataaga aaaagcagct ctataaacag gagttggctt
     4561 ggatgaggac acagccacag gcgcgtgcga ccaagcagca ggccagaatt aaccgctttg
     4621 aacagttaaa aaaggacctt catcaggaaa ggcctataga tcaattggat atggcctttg
     4681 aagccagtcg tattggcaag aaggtcatta atttcaagga ggtttccttt gcttatggtg
     4741 atcaggccat tattgagcat tttaatctga ttattcaaaa taaggaccgt atcggaattg
     4801 ttggagctaa tggtgctgga aagaccaccc tgcttagctt gatgactggt gacttaaaac
     4861 caacagctgg tcagctagag attggcgaga cgatccgtat tggttatttt tcgcagcaaa
     4921 tcaaagatat ggacggcagc aagcgtgtga ttagctattt gcaggaggtg gcagatgagg
     4981 ttaagaccag tgttggcacc actagtatca gtgagctttt ggagcaattt ctttttccgc
     5041 gttctagtca tggctcctta atcgctaagc tatcaggcgg ggagaaaaaa agactgtatt
     5101 tgctaaagct cttgatcgaa aagcctaacg tcctgctgct agatgagccg accaatgatt
     5161 tggatattgc aaccttaaca gtgctggagc attttttagc tcaatttgct gggccggtca
     5221 ttacagtgag tcatgatcgg tatttcttgg ataaggttgc aacaaaggtg ctagcttttg
     5281 agcatggggc tatcagagaa tactatggta attatagcga ctatttagat gaaaaggctt
     5341 ttgaagcaga ggtcatagag cctgctgtca gtgagcaaaa agctggcact gaccatcagg
     5401 tcacctctaa aaagagaatg tcctatcttg agaaaaagga atgggcagct attgaagaaa
     5461 agctagctgc tatcgagcaa caaatagcta ctattgagga gcaaatgctc ggagcggcaa
     5521 gtgattacga ccaattggca caatatcaaa aggagctgga tcagcggaac cttgagctgc
     5581 ttgaagccta tgagcgcttt gattacctaa gcgaattaga agaataatta attatgtgtc
     5641 aatttcatat ttttgtgtta aactagttat agacaaaaag aagtgctagc ttgcgcttct
     5701 tttcatatca ctattatttg ggaggaaatg aatggcttta atttggtcct atttaaaaac
     5761 aagacctaag tggatttgtt tggatattgt gggcggcttg ttatttgttc tggtcaacct
     5821 ggggctacca acaatattgg ctcgtatgat tgatcaaggc gttatgcagc aggatcaaag
     5881 ggctctttat ttttgggctc tgatgatgtt tgttatcgtg cttttaggtg tcgttggacg
     5941 ggtgattttg tcttatgctt ctggcaagct aaccactaac atgatcaagg atttacgtaa
     6001 tgacatgtat agctgcttgc aggattattc gcattcagaa tatgaaaaaa ttggcatagc
     6061 ctccctggtt acccggataa caaatgatgc ctttgttttg atgcaatttg ctgaaatgtc
     6121 cttgaggctg ggtgtcgtga ctcctttgat gatgatcttt tcagtggtga tgatcttttt
     6181 aaccagtcca tcattggctt ggattgtggc tgttgccatg ccttttttag ttattgtggt
     6241 gctttatgtt gcggtaaaga caagaccctt atcagaaaag cagcaggaga gccttgatcg
     6301 tattaaccaa ttggtgcgtg aaaacctgac aggtctgaga gttattcgag cctttgcaag
     6361 agaagacttt caagaagagc gcttcaataa gcgcaatgat cactattctg gaatctcaaa
     6421 gcgactattt accttgacag gcttaacaga gcccttattt gtgcaaatta tcattgctat
     6481 gattgtgggg atcgtctggt ttgccttgga tcccttggca agggggcagt ttaagattgg
     6541 tgatttggtg gcctttatcg aatatagctt tcatgctctt ttttcatttt taatgtttgc
     6601 caacctcttt accatgtacc ctaaaacagc agtgtcaagc aagcgtatca aggaagtgct
     6661 ggatatgccg atttcgattt ctaaaaatga agatggtata acagcgtcca caacacgtgg
     6721 ttatctagaa tttgataacg tgacctttgc ctatccgggt gaaacggaaa gtccagtttt
     6781 acataacatc tcatttaaga ctaggcctgg agagaccatt gcttttatcg gctcgacagg
     6841 ttcaggaaaa tcatctttgg ttaatctgat cccacgattt tatgacgtga ccttagggag
     6901 aatcttggtt gatggcattg atgtcaggga ttatcaatta aaagcgctgc gttctaaaat
     6961 cggctttatt cctcaaaaag ccctgctatt tacaggaacc attgaggaaa acctaaaata
     7021 tggtaagtca gatgccagcc acagtgagct tgagcaggca acagaggttt cccaagcgaa
     7081 ggactttatt accagtcgtg aaaagggcta tcaaacccat ctagctgagg ccggcagtaa
     7141 tctatcagga gggcaaaagc agcgcctgtc tattgccaga gcagtggtca agcagccaga
     7201 catctatatc tttgatgatt ctttttctgc cttagattat aagacagatg ctgaattacg
     7261 cagacggctg aaagaggtga cacaagatgc aacggtctta attgtggctc aaagggtggg
     7321 cacaattatg gatgctgatc aaatcattgt cttggatcag ggagaaattg ttggccgagg
     7381 cacacatgag gaattgctcg caagcaatgc catctatcgt gaaatcgcta attctcagct
     7441 aaacaaagaa gacatgacaa aagaggaggg ggattaatga ctgaaaagca tgtgtttaga
     7501 agaatttgga cctaccttag tgcttatagg ctctcactga taactgccat taccttaaaa
     7561 atagtgagtg ctgtgatgag tgtcttggag ccctttgttc ttggcttggt gataacagag
     7621 ctatctgcaa acctattaga catagcaaag ggagtttctg gtgcaggtat taataaaccc
     7681 tacatcgcct ttcttttagt tctctatatc attagggctc ttgtttatga gttaggctct
     7741 tatggttcaa attattttat gacgaaggct gtgcaatcag gcattcgtga tcttcgtcga
     7801 gacctcagtc aaaaaattaa tcgtatccct gtgtcttatt ttgataagca tcagttcggc
     7861 gatatgctag gacggtttac ctctgatgtt gagacagtct ctaatgccct gcagcagtcc
     7921 tttttacaaa tcgttaatgc cttttttacc cttattttgg tggttggcat ggtcttgtat
     7981 attaatgcac ccttagcctc tgttgtgatt atcgctatcc cgttgatata tgctgcttct
     8041 cgatttgttt taaaaaaatc acagccttat tttaaagcgc aggctaatat tttgggagaa
     8101 atgaatggct ttgtgcagga aaatttgacc ggctttaata ttttaaaact gtatggtcgt
     8161 gaagaagcct caaaggagga atttcaccag atcactgagc gattacaaga agtaggcttt
     8221 aaggccagct ttatttctgg gatcatgatg ccagttctgc attttatttc agattctgtt
     8281 tacatgattg ttgccttaat cgctggctta caggtgatag caggccgcct gacaatcggg
     8341 aacatgcaag cctttgttca gtacatttgg caaatcagtc agcctattca gaccataaca
     8401 cagctggctg gtccactgca aagtgccaag tcatccttag aacgtatctt tgcagtgctt
     8461 gatgaggcag atgaattgac tattgcccaa gagcatttag aacatgattt aacaggtcag
     8521 gtgtccttta atcaggttga ttttagctat actgcagaca atcctctgat tagaaatttc
     8581 aatttagagg tcaagcctgg tgaaatgata gccatcgttg gtccgacagg agctggcaaa
     8641 accactctta ttaatttgtt aatgcggttt tatgatgtga ataagggctc tatcacagtt
     8701 gatggtcagg acattcgtca gctgtcacgt caggcctatc ggcgccagtt tggtatggtg
     8761 ctgcaggacg cttggctatt tgagggcagc attcaggaaa acttgcgctt tggtaattta
     8821 gaggcgactg atgaacaaat aattgaggct gctaaggctg ccaatgttga tcatttcatt
     8881 aggacattgc caggtggcta tcatatggtg atgaatcagg aatctagcaa tatttccttg
     8941 gggcaaaagc agttgctgac cattgctcga gctcttttag cagatccaaa gctactaatc
     9001 ctagatgagg ctacctcatc tgttgataca cgtcttgagc ttttgattca aaaagccatg
     9061 aagcgattaa tggttggcag gaccagcttt gttattgctc atcgcttatc aaccattcaa
     9121 gaggcggata agattttagt cttaaaggat ggtcagatta tcgagcaggg aaatcatgac
     9181 agcctattgg ctgctaaggg cttctattat gagctttatc atagccaatt taaagctact
     9241 cagtcttaaa aagcttaggg tcttggaatg aattattcca agactctttt catttggttt
     9301 agatcatagt aaaagcttga catca
//
LOCUS       DARYSY010000066         9091 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYSY010000066 DARYSY010000000
VERSION     DARYSY010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(581..1405)
                     /gene="nadE"
                     /locus_tag="TVR04_001702"
     CDS             complement(581..1405)
                     /gene="nadE"
                     /locus_tag="TVR04_001702"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1270375.1"
                     /translation="MTLQEDIIRQLGVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQRALAFIQ
                     PDQALTVNIKEAVDGQLRALETAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKALKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(1402..2862)
                     /locus_tag="TVR04_001703"
     CDS             complement(1402..2862)
                     /locus_tag="TVR04_001703"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1270376.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGAMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNELEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(3138..4532)
                     /locus_tag="TVR04_001704"
     CDS             complement(3138..4532)
                     /locus_tag="TVR04_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1270377.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGIFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVTVGVSALINILPGVSDAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCRKALKH"
     gene            complement(4653..5570)
                     /gene="trxB"
                     /locus_tag="TVR04_001705"
     CDS             complement(4653..5570)
                     /gene="trxB"
                     /locus_tag="TVR04_001705"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1270378.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYNTKT
                     VIVATGAKHRLLGIAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTNHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGTIAGQGVYHYIESLSS"
     gene            complement(5630..5857)
                     /locus_tag="TVR04_001706"
     CDS             complement(5630..5857)
                     /locus_tag="TVR04_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1270379.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(5967..6710)
                     /locus_tag="TVR04_001707"
     CDS             complement(5967..6710)
                     /locus_tag="TVR04_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1270380.1"
                     /translation="MIKVTHLTKSFSGQKVLDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSIAIDDFAVDFEHITKQDMLTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGTPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(6710..7513)
                     /locus_tag="TVR04_001708"
     CDS             complement(6710..7513)
                     /locus_tag="TVR04_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1270381.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLLLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASVFAITAFAFNEAAYTSETIRAAIQSVDAGEIEAAKS
                     LGMTSVQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYKMAIKAPVPTNNSKIGELR"
     gene            complement(7889..8716)
                     /locus_tag="TVR04_001709"
     CDS             complement(7889..8716)
                     /locus_tag="TVR04_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1270382.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKEHSITGYDIEVLKRVFKGSKKYRLSIEVVPFPSILTGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPLTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
BASE COUNT         2781 a         2136 c         1697 g         2477 t
ORIGIN      
        1 tcttcaagta aaaaaattag gctaacttaa ttttttaaag ctaagcagca gctttccaac
       61 agccagacaa agagccttct aaaaagacga caaaacctgc tggactttga gcacctaaac
      121 atgtcatatg tccacctcag catgaactca aagaagctag ctgtatctag tcttcacgtt
      181 atctcagtga ttagcacaaa aaattgtctc tactgcagca aaagcaattg ataggacatt
      241 atcagctagt ccaagaaact gcaggtagct agctgaaaca tatagcaaag ctaaaaccag
      301 agacctccca accttaaagc ctctggtttt tagttagctg agcattctcc tttatcttgg
      361 ctgctttaag atagtgacaa atcaacacct acaccaatcc tgttaaggaa gccttaagcc
      421 aggtccttca tagggctaag ggtgagggaa gctcttaggc aacagctact ggatttatgc
      481 ctaatagaag ctcctgtccc tcctcactta ttaaacatag cattggttta tctatagtct
      541 acgtaggttt ggtcatcact tctaatctaa cagggaagga tcacttccaa aagtcatcaa
      601 aaatagtaat tggcagatgg cgcttgtgct gccctttatg ccaccagtct tcaatccttg
      661 cctgagcttc agcggaaatc gtatgcccct ctaagtaatc gtctatctct tgataagtaa
      721 cacctaatgc tacctcatct gcaagtcctg gcttcttatc ctctagatct gctgttggca
      781 ccttctcata gaggctgggg tcagccttta gcgcctttaa caaggcctta ccctgccgct
      841 tagtcaagcg aaaaaggggt agaatatccg ctccgccatc accaaactta gtgaaaaagc
      901 ccgtaacatt ttcggcggca tgatctgtcc caatgacagc accagctgtt tgaccagcga
      961 tagcatactg actaatcata cgctgacgtg ccttaatgtt tcccttatta aagtcagaaa
     1021 tctcaagccc tgccgtctct agggctctta gctgaccatc aacagcctct ttaatgttaa
     1081 ccgtcaaggc ttgatcaggt tgaataaatg ctaaggctct ttgtgcgtct gcctcatctg
     1141 cctgaacacc atagggcaag cggacagcga taaattggta ctgctcatca cctgtttcag
     1201 cgcgcagctc ttcaatcgcc atctgagcta gctttccggc taagctggaa tcctgaccac
     1261 cagaaatccc taagacataa gtctttaaaa aagggtgctt taacaaataa gcctttaaaa
     1321 aatcaaccga ctggcgaatc tcctgcttag gatcaattac tgctttgacc ccaagctgac
     1381 gaatgatatc ctcttgtaat gtcatatcaa atcactcctt ttacaggctt ccttgcgaat
     1441 tttgtcaatg agatgcatct tattttgcca aacatcaagc gcaagatcca caggatagtg
     1501 ctgtggattc aagacacgct tgtattcgtc ccaaagctta tcaaattcct ttctagcata
     1561 agccttgatg tcttttaagc ttggcagctg ataaactagc tttcctttat caaaaatatc
     1621 tactagcaaa ggaacagcat caaaatctct gacggtttta ttaatgtagg tataagtcgg
     1681 gtggaacatg tgaatttctt ctagctcatt aacattaaca cctgtaaagg tgatgtagtc
     1741 gccttctgac ttgccctttt cgcggctggt aatccgccaa acctgctttt tacctggtgt
     1801 tgataccttt tcagcattat ttgatagctt gatggtatca cgcatggcgc catctgcctg
     1861 ctctatcgaa acaatcttat aaaccgctcc cagagctggt tgatcatagg ctgtaatcaa
     1921 ttttgttcca acaccccaaa catcaatttt agccttttgc attttcaggt tgaggattgt
     1981 attttcatct aaatcattgg aagcgtaaat cttagcctct gtgaagccgg cagcatccag
     2041 ctgctggcgt acccttttag ataggtaagc aaggtcgcca gaatccagac gaacacccaa
     2101 gaaattaatc ttatcaccca attccttggc cacacgaata gctgttggga cacctaccct
     2161 caaggtatca taggtatcaa ccaagaaaat acaatccttg tgcacactgg cataggcctt
     2221 gaaagcatca taatcattac cataggcctg taccagagca tgtgcatgcg tgccagacac
     2281 aggaatgtca aaacgctttc cggcacgaac gttactagtt gcgtctgctc cgccaataat
     2341 ggcagcacgt gtcccccaaa cagcagcgtc catctcctga gcgcggcgtg tcccaaactc
     2401 taaaagtggc tcatcttcaa taacagagcg aatacgagct gcctttgtag caatcaaggt
     2461 ttggaaattc acgatattca aaagagctgt ttctactagc tgacattgac ctaaaggtcc
     2521 ctcaacctga acaataggct cattggcaaa aaccaaatct ccctcttgtg ctgagcgaat
     2581 cgttagctct aaacgaagct ctctgagata ggtcaaaaaa gcagggctgt agcctagctc
     2641 cttcaaataa gccaaatcgg tctcagaaaa ggtcaattgc tcaaggtatt ctacgattcg
     2701 ttgtagacca gcaaaaactg cgtagccatt gttaaaaggc tctctacgga aataaacctc
     2761 aaagacagca ttacgattat gaatgccctg ctcaaaataa acctgcatca tatttaattg
     2821 atataaatca gtatgaaggg ttaagctatc atctctgtac atataagtaa ctccttaaca
     2881 taattgttat tattatacca tatttttggc atagacctgt aagactcaac taaaatcctc
     2941 tgctcaagct ttctaaaaaa aaagccttga gctgctatta agcctgacat attttttgcc
     3001 agtaccttcc taaaaagtct atagcacaag ggcttatggc tttttaacaa aagcagtttc
     3061 agttgatagc attcataaaa aaagattgaa gaaattgacc aaaatagccc ttttcttcaa
     3121 tctgtttaac tcacacctta gtgctttaac gcttttctac acttgagctg actatagcag
     3181 ccaaagacta ggatccaaat gctagcaccg attgccccga tataggtgga cttctgtaaa
     3241 aacagggaaa taaaaacaaa ggcaaaaaag gctagggtca atggcgttgt tagctgatag
     3301 cttggcatca aataaccatc tggcataaag tcactggatt gacgatattt ccaatgcgca
     3361 agcatggtca aagcataaat cgcaatataa acaccagatg aggaggccgt aatcagcgaa
     3421 aaggcgtctg aaacacccgg cagaatatta atcaaggccg acactccaac agtaacagct
     3481 gaggcaataa tagccctgct tggtacccct tgacgagaca gagtgttaat ccttaaggct
     3541 ttagtaagag catttggggt ctcattagcg atttgataca aatgccgccc tgtcgaatac
     3601 aaggtcgaat ttagggctga tgccgctgat gttaagacca caaaattaat taaagcagca
     3661 gcccatttaa tcccaatcag cttaaagacc atcacaaagg gagattcgtc cgtaggcagc
     3721 tgataccaag gcacaatcgc cataatagac accaaagcac caacgtaaaa aatgacaatc
     3781 cgcatcggaa tctcttggat agcctttggc aagacctttc taggatttgc ggtctctgag
     3841 gttgtaatac caacaaattc gatggcctga taggcaaaga aaaccatctg aaaggccatg
     3901 aaaaatttca acttcccatt cggaaatagt gaaaaatgat ccacaatatt ggcaaggctg
     3961 gcatgaccga catgcgtttc aaagcccgtt agaaccataa aaacggctgt tgcaatcaag
     4021 gctaaaatcg caacaatctt aatcatggca aaccaaaact cagtctctcc aaagacccgc
     4081 acagcaatta aattgatgga gctaagcaac accaaaaaaa cgagctgaat cagccaagat
     4141 ggccaagcag gaaaccaaaa ctgaacatag gaggcgacag ctgtaatctc tgccatgcca
     4201 ataaagatca gggaaatcca gtaagaaagc ccagaaaaat agccccagcc tggcccaata
     4261 tattttgtaa tgaaattgat aaaggtatgc tgatccggat catagtacag catctcacca
     4321 atagcccgca tcatcaaaaa cataaagata cctgtaatca tgtaaacaaa gataatagac
     4381 ggacccgtta aggcaataga acgaccagct cctagaaaga gacctgttcc aatagtgcct
     4441 gctatggcaa tgagctgaac atgtcggttt tgcagccccc ttaccatgcc attctcaagt
     4501 tctttagtgc ttttagcttc ttttgtagac atttgactct ccattcaatt aaaaaaaaca
     4561 ccactattat atctgttttt cagaaaatgt tcaactttct ctaaggcttg caaactaaaa
     4621 aggtcaactg aaccttttta gcgttgacct ttttaagatg ataggctttc aatgtaatgg
     4681 tagacgcctt gaccggcaat ggtaccatct ccaactgctg ttgtgatctg acgtagctgc
     4741 ttttgacgaa catcaccgac agcaaaaata ccaggaatac ttgtcttcat ttgatcgtct
     4801 gtcacaatcc agccctcttg attggtaatg cctagctcag ataccatttg agtaactgga
     4861 atcaagccga catagataaa gacaccacca aagtcatggt tagtcacttg acctgttttg
     4921 acattttcaa tcacaacatt agaaacctta atgtcgtttc cttgaatctc cttgacaaca
     4981 gaatcccata taaaatcaag cttttcgttg gcaaaggcac gctcctgcaa gatcttttgg
     5041 gcacgcagct ggtcacgacg atgcacaatc gttaccttct tagcaaactg ggtcaggtag
     5101 atcgcttcct caactgctga atctccacct cccacaacta atagctcctg attgcgaaag
     5161 aaagcgccat cacagaccgc acaataagaa acacctcggc tggtgtactc ctcttctcca
     5221 gcaataccta aaagacgatg ctttgctcct gtcgcgacaa tcactgtttt agtattgtag
     5281 tgcgtatctt ctgtgtacac acgcttataa tcaccacaat cctcaaccct ttgaacaatg
     5341 ccataaatgt tttcaacctt aaatttttca agcggctcat acatctttag cgatagctcc
     5401 ggtcctgaaa tgtgatcata gccaggataa ttttcaatat ctgatgtgtt attcatttga
     5461 ccaccgggtg ctccctgctc aataatgcca actcgtaggt tactacgtgc tgcatataaa
     5521 gcagctgtca taccagcagg tcctgatcca ataatgagtg tatcgtacat gggttaactc
     5581 ctcttaatag tcttgtcatc attttaacaa tagctacatc gtattgcaat tatttcgcct
     5641 tcaataccac tagaatgctc ataaaggcaa aggacaaaat cggaatcgtc aaaatagcaa
     5701 ccatgatcat ctcatataaa aatgcctgtc tctggagaat ggttttatcc tttttggtca
     5761 cagcacgcca taaaatccac aaaagacaaa gcatgaccat cgtaatagct gctaacaaca
     5821 gaccttccaa ataaaagcga aaaatttcta ctaacatctt tatctacctg attaccataa
     5881 ccttttttca tggcagctta gcttttaagc acatacaaga aaagcctagc ctacctagac
     5941 ctttttatta tatcaaaagc cggcttttaa atatacgttt ttgcatagtt tgcaaaaaat
     6001 tcctttgttc ttgcttcctt agggtgtcta aagatctgct caggagttcc ctcttcaaga
     6061 attttcccct tgtctaaaaa aagcacccta tctgcaacct gataaacaaa agccatatca
     6121 tgactcacta aaatcatcgt ttgacctgcc ttggcagcat caataataga ccgttcaacc
     6181 tctccaacca gctcagggtc taaggctgag gtcggctcat ctaataagag cacatctggc
     6241 ttcattgcta aagcacgtgc aatagcaacc ctttgctttt gaccgccaga tagatgacga
     6301 gggtaatggt tttcgcgatc agacaagcca accttagcta attctgctct agctatgtct
     6361 gttgcttctt ggtcagacag ttttttaact atttttaagc cttccttgac attgtcaagc
     6421 gctgtgcggc gttcaaagag gttaaattgc tgaaaaacca ttgctaattt tcgtctaagc
     6481 gttagcatgt cttgttttgt gatgtgttca aagtcaactg caaagtcatc aatagcaata
     6541 ctccctgtgt ctggctgttc aagataattc atgcttctaa ggaaggttga tttccctgcg
     6601 cctgatgcac caaccaaggc gatgacctga cctttttcaa tcgtcaccgt taggtcgtcc
     6661 aagacctttt gcccagagaa ggacttggtt aaatgggtta ccttaatcat tagcgcaatt
     6721 ctcctatctt gctattattt gttgggaccg gtgctttgat agccattttg tattcaatca
     6781 agcgaccagc ctgctctatc aaaatactaa tgccccaata aactaaggca actgaaatat
     6841 aacgttcaaa ataacgataa tctgctccac ctagaatctg ggcctgtgca aacatttcaa
     6901 cgatgcctgc attgaaggcc aaagaggttc cctttgtcag gcctatcaag ccattaatca
     6961 gggtcggtgt tgccacaaca gcagcatttg gaatgatgac tcggcgataa acctgaacag
     7021 aggtcattcc taagctctta gcagcctcaa tttcacctgc gtcaacggat tgaatcgcag
     7081 ctctaatggt ttcactcgta taagcggctt cattgaaggc aaaggctgta atcgcaaaaa
     7141 cagaggccgg aatggcatta atattccagt caaagccata gcgttgattt aagaatttca
     7201 gaaaaagagg aataccatag tagctcagca ttagctgaac caagatgggt gttccacgca
     7261 aaaagctaac aaaaaccgct tgaatcggat aaagaatgcg aaccctattg attttgacaa
     7321 tggcaaaaac caaggctaac aaaaggccca aggcagcacc agctattgtc agaccaagtg
     7381 tgatcggcaa acgcctgata atatctggaa tggcatcaaa aacagcatgc cagctaaata
     7441 gcttcccttc tgggatcaac gagatgagct tgtcatacca agcccaacca cttgttaaaa
     7501 acgtagatgt catgtatcgc ccctttgtac tgttttatct caatattttc attttaacat
     7561 tcttgagagg tcatgtaaaa tagtaaatcc gcatgataac gataagaaaa gcctatcgca
     7621 gaggatagga ctcaagctaa ggaaaaaact cttttagctg cctgtgacag tatctccttg
     7681 gagctaccaa gcttgatctt gagctgcact ctcaaagcct caaaatggct gattctaaag
     7741 gaatacagcc actggtacaa gactaacaat cagctactag gccaaaaagg tcaaaagctt
     7801 ggctagctgg cacagctaac tgcctcaaag gctaggtcaa cgaaagattg aagcctgccc
     7861 agggcttgag ggcttttagc cctgtcaatt aattgacctt ggagataaag tctcctccca
     7921 aaaatgcttg gctgagcttt ctgagctgac ctgatttttt aagcttagcc agccttttgt
     7981 tgacaaagct ctgtagagcc ttaccctttt gatcattggc aaacacataa tattccaagc
     8041 cgtccttagc agtatcagcc tgctccttga gctttgtcac atgcacatca aagccttgct
     8101 cctcagctac ggttgttaga gaaatagcgt catagaaaag aaagtccagc tggccattct
     8161 ccagcagctg cagcctttgg gtcaatgggg ttgactcaga agcataggtg agatgaatag
     8221 gcttttgatc agggtgagat tggttccatt tttcaaggat aagcatgtaa ttggagccag
     8281 ctattccttg ggttttcttt ccagaaagat cagctaagct tttatactgc tgcttaccct
     8341 ttgttgccag agcataatgc gaggccgaaa tagggcttga aaacaaatac ttttcagctc
     8401 tttccttact atagccaaaa ttattggccc caatctgata acgacctgca tcaataccag
     8461 tcagaatcga tggaaaagga actacttcta tgcttaaccg atactttttg gagcctttaa
     8521 aaaccctttt cagaacctca atatcatagc ctgtaatgct atgctccttt ctataggtaa
     8581 agggcttggt tgcagcatct gttgctactc tgatcacctc tttttgacga gctgtgacct
     8641 catggctagt cacgactgcc aagagtccta gactagctag caaaaaaaag agtgctcgct
     8701 gtaattgttt tgtcatacca tactcctatc tcttatacag tagccatttt aacaaaaaat
     8761 gataaatttg aataatatca tttctctatc aaggcaataa gaaaatagta tcaaacaagc
     8821 aattaaaaca gcacattctt catttacctg atcatggatt aaccacaaca gacaagcttt
     8881 agctattagc aggctgccta agccaaaatc aacacctcaa gctttcaact gactgatgta
     8941 aaagctagta gtcacctcta caagaagaaa aagaactgtt tgtgtcattc aaccagtagc
     9001 acccttctta actggtcatt cctatccagc tctactacta ggctatcagt taacgatcag
     9061 aaaaaaagtt gacctatctg ccttatgaag c
//
LOCUS       DARYSY010000067         9032 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYSY010000067 DARYSY010000000
VERSION     DARYSY010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9032
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            303..1010
                     /locus_tag="TVR04_001710"
     CDS             303..1010
                     /locus_tag="TVR04_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270383.1"
                     /translation="MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFL
                     DSVAGIIQYDKGNVSLDGHASGSDAFKTNSFYIPSDSYLPEYLTGREYAAFIQSRYAN
                     ANGSVFVELSRLLDMTEALDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDL
                     ETVILIQELFSLYAREHKLLLVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYI
                     YQKGRITEKLQRIAEIL"
     gene            1015..2364
                     /locus_tag="TVR04_001711"
     CDS             1015..2364
                     /locus_tag="TVR04_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270384.1"
                     /translation="MSFYYNDALNGFLNRPFFKKKKNQYLVAIVGFVLYFGYFLANVR
                     EIGRLGFGARQLDTETLIALTRLTIMSYINMCLIISIALFVFVNSVISLTKSSVYITN
                     ILPYSKREILIAQKMFKMGVALIGYEALLLLVFPLFGQLPIIKLSDQFLLLLLFHVLF
                     IAVFLIVDACYAVLARATARYKKCSIGSLVFGLDIFFTLFCVAYLVYFKIGIDTFIGK
                     LPIGLTALIVLALLIASFVLIVVSQLSYRYALTIQHYKKSSYGLVRLPMIRLNLMTTF
                     PAIYRHKSFIHSLALITVFSLIISYQLGLKSGLETFANLNALLTFSAVNYADATAKIR
                     KYYHFFRVSLKEEVLSLVLGGIVVSMAPFLISLYFGGSMLAFFLSMAIYLCAVIAGLL
                     FPTTQGNLNEAASTTTTIFLSIALYLILKHDSLYISSAILSVLVLVLSVCLARERRG"
     gene            2366..2644
                     /locus_tag="TVR04_001712"
     CDS             2366..2644
                     /locus_tag="TVR04_001712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270385.1"
                     /translation="MGKRIMTDIKWGSMLYLFLVVIDLMIELFQIDESGTVITLFGIK
                     IISRITLHELNTTFLLDNRLLLSYAVTISLCLLVGYFWTRRGSKEPLK"
     gene            2641..3006
                     /locus_tag="TVR04_001713"
     CDS             2641..3006
                     /locus_tag="TVR04_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HEL1270386.1"
                     /translation="MTTVELVLQLPLALLTIALHELLHYLVAYLLGYKPKFGWERKLI
                     PFVSFPNKNRDIDNLLIALAAPVGLFVIGMLIPRSIAFLSLVRIICLLNILHVFPWCT
                     DGQVILLSLIHCCQKGGRV"
     gene            3003..3506
                     /locus_tag="TVR04_001714"
     CDS             3003..3506
                     /locus_tag="TVR04_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1270387.1"
                     /translation="MRKSMKALAIGIVMVICLVGGYYWAIGKAKKPAYAVNTPQFIHE
                     RPDVVLRRLENGEQGVYYFGFADCPWCVELLPVLDEALAVSDLQAYAVDTKGKDFTET
                     LRSRLSRFYARYYQNHLSVPFLVTILEDGKVQTHVGTLEKHNAHEEPLTDKQKKELKK
                     IVLALLR"
     gene            3737..4096
                     /gene="rnpA"
                     /locus_tag="TVR04_001715"
     CDS             3737..4096
                     /gene="rnpA"
                     /locus_tag="TVR04_001715"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1270388.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHALMELGDHLKTEDFVVIARRGTEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            4080..4889
                     /locus_tag="TVR04_001716"
     CDS             4080..4889
                     /locus_tag="TVR04_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1270389.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            4901..5800
                     /locus_tag="TVR04_001717"
     CDS             4901..5800
                     /locus_tag="TVR04_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1270390.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRGVPEEINRQNAPVVNPDEVELEELKAVRSEGKRV
                     AQSVAHQSINPSSTDQSVPAQSKAQPALSAAGMSQLDPAAADTSKDIELAAQEVSDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            6422..7684
                     /locus_tag="TVR04_001718"
                     /pseudo
     CDS             6422..7684
                     /locus_tag="TVR04_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8161..8619
                     /locus_tag="TVR04_001719"
     CDS             8161..8619
                     /locus_tag="TVR04_001719"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270391.1"
                     /translation="MMFNIKKNSDTISGKVAYSTEGQEIKVQPSINSDITFLIAYLQL
                     GFDSENMLSTQISGYLPCFNWEAACLAKPLAVKGRILLCRSDIEPGDSVRIPNVEYWK
                     IQYDNASGWLRYGNVTDLRGITYVEIFQNELVGLNSDGHIEEIWLKPVWL"
BASE COUNT         2589 a         1539 c         2062 g         2842 t
ORIGIN      
        1 ctgttcgtaa tcatgctgcc ttattttgga tttttgttct attgatagtt ttctactttg
       61 ggtatgccta ttattgtact agtcgtggtt ataatttctc agggatagca aacttcttta
      121 gtggtggtgt taacattggt tgttatagat aactgttaat atttcatttt tagattagta
      181 tttaatgagt tgtaaacacg agtgagctag tttctagaga gtctgtagtt tattcgcttt
      241 tcgcttttaa tagcccatca tgtcctattc tcagacagca gattattatc ttaggaggtc
      301 gtatgcttga agtcaaaagc ctgtgtaaat catttggcag tcattgtgtt ttggatcatt
      361 tatcaatcac acttggaaca agagggatta ctgttattgt tggcttgaac ggttcgggaa
      421 agactgtttt tctagattcg gtagcaggaa taatccagta tgacaaagga aatgtctcac
      481 tagatgggca tgcgagtggc agtgatgctt ttaaaacaaa tagcttttat atcccatcag
      541 attcttatct gccagaatat ctaaccggtc gtgaatatgc ggcatttatc caatcacgct
      601 acgctaatgc taatggctct gtatttgttg agctttcccg tcttttggat atgactgagg
      661 cattagatag accaatagaa gcttattcat ttggtatgaa aaagaagctt caaattgctc
      721 tggggctttc tttgaatgtg ggatatcttc ttgcagatga ggcatttagt ggattagatt
      781 tggaaacggt cattcttatt caggaattgt ttagtcttta tgccagagag cataagcttt
      841 tgcttgtttc tcatgagcga catattatca atcaattttc gactgatatt ttattaatgg
      901 agaaagggaa actaactgag tttagaggta cagcagatga gctttctgac tatatttatc
      961 aaaaaggaag gattactgag aagcttcaaa gaattgcaga aatcctttga gttagtgtct
     1021 ttttattata acgacgcttt aaatggcttt ttaaataggc ctttttttaa gaaaaagaaa
     1081 aatcagtacc ttgtagcgat tgttggcttt gttttatatt ttgggtattt tttagcaaat
     1141 gtacgtgaaa ttgggcgatt gggttttggg gcaaggcagt tggatacaga gacgcttatt
     1201 gcattaacac gcctaacaat catgagctac attaatatgt gtcttattat ctcaattgct
     1261 ttatttgtat ttgtgaactc ggtaatttca cttactaaaa gctcggttta cattactaat
     1321 atccttccct acagcaaaag agagatttta atagctcaaa aaatgtttaa gatgggagtt
     1381 gcactgattg gatatgaagc actgttactt ttagtgtttc ctttgtttgg ccagctgcca
     1441 attattaagc taagcgacca gttcctcttg ttattgctct ttcatgttct ttttatagca
     1501 gtatttttga tagtagatgc ctgctatgca gtgctagcaa gagcaacagc aaggtacaaa
     1561 aaatgttcaa taggctcact ggtctttggc ttagatatct tttttacctt attttgtgta
     1621 gcctatttgg tttattttaa aatagggatt gataccttca taggaaaact tccaataggg
     1681 ttgacagcgt taatcgtact tgcattactg atagctagct ttgtgcttat tgtggtatca
     1741 caattaagct atcggtatgc tttgactatt cagcattata agaagtcatc ttatggctta
     1801 gttagattac caatgattag gcttaaccta atgacaacct ttccggcaat ttatagacac
     1861 aagagcttta ttcattcact agccttaatt accgtttttt cactgattat ctcttaccaa
     1921 ttggggctta aaagtgggtt ggaaaccttt gctaatttaa atgctctttt gaccttttca
     1981 gcggttaatt atgcagatgc aacagctaag ataaggaaat attaccattt tttcagggtt
     2041 agcttaaagg aggaggtcct ttcgctagtt ttagggggaa ttgtggtctc tatggcgcct
     2101 tttctgattt ctctttattt tggtggctca atgctagcct tcttcttatc aatggcaata
     2161 tacttatgtg ctgtgatagc aggtcttctt tttccaacga cacaaggtaa tttgaatgag
     2221 gctgcttcga cgacgacaac gattttttta tcaatagcat tatatctgat actaaagcat
     2281 gatagccttt atatttcatc agcaattcta tcagtgctag tgcttgtatt gagtgtatgt
     2341 ttggcaagag aaagaagagg ttaatatggg aaaaaggata atgactgata tcaaatgggg
     2401 cagtatgctt tatctgtttt tagtagttat tgatttaatg atagagcttt ttcaaattga
     2461 tgagagtggc actgtgataa cactttttgg tataaagatt attagtcgta taacgctaca
     2521 cgaattaaac acaacattct tactagataa taggcttttg ctttcttatg ctgtgacgat
     2581 ctcgctatgc ttattggttg gttatttttg gactcgtaga ggatcaaagg agcccttgaa
     2641 atgacaacgg tagagcttgt tctccaattg ccactggctt tgttgaccat agcccttcat
     2701 gagcttcttc attatctggt tgcttacttg cttggctata agcccaagtt tggctgggag
     2761 aggaaactga ttccttttgt gtcgtttcct aataaaaata gagatataga taaccttttg
     2821 attgctttag ctgctcccgt aggccttttt gtcattggta tgttaattcc aaggtctatt
     2881 gcttttttat cactagtaag gatcatttgc cttttaaata tcttgcatgt ttttccatgg
     2941 tgtacagatg ggcaggttat tttactatca ttgattcact gttgtcaaaa aggaggacga
     3001 gtatgagaaa aagtatgaaa gctttagcta ttggtattgt catggtaata tgccttgtgg
     3061 gaggatatta ttgggctatt ggtaaagcaa agaagcctgc ttatgctgtt aatacccctc
     3121 aatttatcca tgagaggcct gatgttgtgc ttaggaggct tgaaaatggt gagcagggag
     3181 tttattactt tggttttgct gattgtcctt ggtgtgttga actgcttcca gttttggacg
     3241 aagctttagc ggtgtcagac ctgcaggcct atgctgtaga taccaaaggt aaagatttta
     3301 cagagaccct tcgttctcgc ttgtctcgat tttatgcccg ttattatcaa aatcacctct
     3361 cagttccttt tttagttact attctggagg atggaaaagt tcaaacccat gttggtacac
     3421 ttgaaaaaca taatgctcat gaagagccac tgacagataa gcaaaaaaag gaactgaaaa
     3481 aaatagtatt agcattactt cggtagctat agctgatcta aaatacatca ggtaaggctt
     3541 ggtgtatttt ttgtttatgg ctagtgtgag ccatgactgt atcaggacca tacagatgct
     3601 gctatcctca aaggctctct tttttctagc tttgactggt agtccgttaa tctgtcatta
     3661 ggctaacgtg ataagggttg aggcttttta atgttttatg gtataatggt aataatttag
     3721 atatgggagt taagttttga agaaaagcta tcgtgtcaag cgagagaaag atttccaggc
     3781 gatttttaag cttggtcaga gcatggcaaa tcgaaaattt gtcatttacc atttgaaagg
     3841 ggaacacaag cattttcgag cagggatttc tgttggcaaa aagctgggaa atgctgttac
     3901 tcgaaatgcg gtaaagcgca agatacgaca cgctttaatg gagctgggtg atcatctcaa
     3961 gactgaggat ttcgttgtta ttgctaggag aggtacagag gagttagatt atcaagcagt
     4021 caaacaaaat ttacatcatg ttttaaagct agcaaaattg cttgaggaag gttttgagat
     4081 tgaaaaaaag agttaaaaca gcagccctag tgccgcttgt cttgctccta gtagcctgtg
     4141 ggcgtggaga ggtgacagca caatcatcta gcagctggga gcaattggtt tatttttttg
     4201 ccaaggcgat ccaatggttg tcctttgatg gatcgactgg gattgggatt atcctattta
     4261 cgataatgat tcgcttactt ttactgccat tgtttaacat gcaaatcaag tcagggcaga
     4321 aaatgcagga cattcagcca gagctaaagg ccctgcagaa aaaatacgcc gctaaggaca
     4381 cagcaactcg tatgaagcta gctgaagaaa gtcaagctct gtacaaaaag tatggtgtca
     4441 atccttacat gagccttttg cccttgctga ttcagatgcc ggtgatgttc gccttgtttc
     4501 agtccctgtc tcgtgtggcc ttcttaagag aaggaacctt tttatgggtt gagctggcgc
     4561 gacacgatca tctctttatc ctgcctattt tagcggctgt ctttaccttt ttatcaacat
     4621 ggctaaccaa tctagcggct agagaaaaga cggctatgat aacgatcatg acctacgtga
     4681 tgcctatatt catcttcttt atgggcttta atctggccag tggtgtggtg ctttattggg
     4741 cggtttccaa tgcctttcag gttgttcagc tcttgttgtt taataatccc tttaaagtta
     4801 ttgccgaaag gcagcgttta gcagatgaag aaaaagagcg tcgagctaag gaacgtcgcg
     4861 ctcgtaagag agcaatgaaa agaaaatagg agtttaggat atggtattgt ttacaggtaa
     4921 gactgttgaa gaagcaattg aaaaaggact tcaagagttg gggttgtcac gtctaaaagc
     4981 acacatcaag gtgatttcaa aggagaaaaa aggcttttta ggctttggta aaaagccagc
     5041 tcaggttgat attgaaggca ttaatgaaaa aacagtctat aaggctgata aaaaagccgt
     5101 acgtggtgtt ccagaggaga tcaaccgtca aaatgcaccg gttgttaacc ctgatgaagt
     5161 ggagcttgag gagttaaagg ccgtccgatc agaaggcaaa agggttgctc agtctgttgc
     5221 tcatcagtca ataaatccat caagcacaga tcagtcagtc cctgctcagt caaaggcgca
     5281 gcccgcgtta tcagctgctg gtatgagtca gcttgatcca gctgcagcgg atacgagtaa
     5341 ggatattgag ctagccgcac aggaggtttc tgattatgtg accaagatta tctatgagat
     5401 ggatattgaa gcctctattg agaggaccaa caatcgtcgt cagatcaatc ttcagataga
     5461 gacaccagag gcaggtcgtg ttattggcta tcatggtaag gttttgaaat cactgcaatt
     5521 gctggcccaa aatttcttac atgaccgcta ttctaagaat ttttctgtct ccttgaatgt
     5581 tcatgattat gtagagcatc ggacagaaac cctgattgac tttaccaaaa aggtatccaa
     5641 gcgtgtgctt gagtctggtc aagattatac catggatcct atgagtaaca gcgagcgaaa
     5701 gattgttcat aaaacagttt ctgctattga tggggttgag agctattcag aaggcaatga
     5761 ccctaatcgc tatgtcgttg tctcactaat tcacgactaa tgtcatcaaa gaggctcaat
     5821 gtcaactgta gtggggtgac taataactaa tatctagaga ggaccagctt ggtgctctct
     5881 tttgtgatgt taaaagtatt gggaatcttg gctttgaagt tcctaaagcc aaagcttgct
     5941 gttctatgtt tttgctcagc ttattggttg cttctaactt agcgtttgaa taagagagtt
     6001 caatgagata ttttttggca acgaataaag gtactaagag cggttttgaa gcttgattta
     6061 tattcgtaat cggatcgaag agatgtcact gttcttttct tgcagataat aaagaatgat
     6121 ttggtaaagg tcatcataat catttagctg aggcactatt tgatgttatc aagaattgtc
     6181 atggttttct tgaccacgtt tgtcccacct atttatatca gcttttcctc ttagtaatac
     6241 attatttgta atactcctgc taacaaggtt ggataagcta tatgctatta accctcaatg
     6301 ctcttagctt ggtgtgataa ccattaagtt ttttgatata ataaaagaga tatattaagg
     6361 aaatatattg ctattattgg tgaaacattt tgatatcgca ttgaaaacgt taggggaaga
     6421 aatgagctat aatatcgaat atgatgagat tacctccctt caacaaagca cccaaaccac
     6481 gatcagtgct tggggagatg ggatgatgag cttacaaacc gctatgtcag tcttaattgg
     6541 agacagtcgc cttcagggtc agaccgctag ctcgatcaag agctacctga gtgaggtgca
     6601 tgggactctc ttacaaaccc tacaaagcct gatgaatgat tactcagcca gcctcttgct
     6661 gtataaggac cgctattact agatagacag taacagccat gcccagttac ctggtcaggt
     6721 ctttaagacc ctgcagtcag agcttcggct ctcgcaggcc cacctcaagg atcagcttga
     6781 gttactacag aatgctagag ctaaggtatc agacttggtg cactactctg gtgtcagtca
     6841 tgccaagaca gtggtggatt atagtgaact gatcactgat atccatcgct tggacgaggc
     6901 catcattcaa tacgaaagca atcatgccag tcaggacttg gccgccttca aggagctttt
     6961 ggcttcgacc aaggccttga tagcagagta cagcagtaag cccaagcggg ctgggagcta
     7021 tcaggttggg gatataggac agctcaacac cataaaacgc tttgcgacag cttatcaggg
     7081 ggtggctcgt tatcttgaga ccaatgccaa gcgtctccaa gcagcgcagg agcgagatca
     7141 ggctcgcttt gaggcaatag ccgcagcgga cagagccagt cagggttggg tggatctggc
     7201 acttagcctt gtgacaatag cggttggggt agcggctatc gtcatgacag caggggcagc
     7261 gactccccta gtggttggag cctgtgtggt cggcagctgc acagctgctt atggcgcgtc
     7321 gaatcttttt gaggctgggc acaacattta tctaggcagc gttggtgatg gactcacagt
     7381 ggctaccaat ccccttcggg ataccttgtt catggggaat gacaggctat accaccaagt
     7441 tggcgggctg ttcacaacag ccagtgcagc cctaatcccg atcggacaga ccaagagtgt
     7501 tgccaagggc ttaacagagt tcacgatcgg ggaggtcggc ggttttatcg gtggccaagc
     7561 cagctatcat ggcaccaggc tcttaggcgg cagtgagcaa gacgcccaaa gagctacatt
     7621 agtagggaat atcttaggag gacttgccgc ctcaagcgct gctagaaggt tcagcttgaa
     7681 tgagccaata gcagctaggg tgacgaaacc gacctacaag cgccagcagc ttttgaagaa
     7741 ccttgaaagc agcagactgg caagggaaag ctcaaggttt aagaattatg gagcaagaga
     7801 aaagttagcg aagtttaggg tagctactga tgaacttgaa aacaattttg aaaatgtcag
     7861 aattaaagca tatgacttaa tgttgacgga tactgttaaa aatcactcga aagatattat
     7921 tcggaaggga aagtatgttg gacagaaagc tagaccttat atagaaaatc cagggacaca
     7981 aacactaatc caagaaatta tggacgctga aaaaccatcg gcagataaat ttttattaaa
     8041 tggattacgg tgggacgtca aaggaagctt caatggaaga agtgaaggga tctgggaatt
     8101 ggttgttgat ttagaaacaa atagaattgt tcattttaat tttacgcgat aggaggataa
     8161 atgatgttta acattaaaaa aaatagcgat acaatttcag gtaaagttgc ctattctact
     8221 gaggggcaag aaattaaggt tcagccttcc ataaattcgg atattacgtt tttaattgca
     8281 tacttacaac tgggatttga ttcagaaaat atgctttcta ctcaaataag tggctattta
     8341 ccatgtttta attgggaggc tgcttgttta gctaagcctt tagcagttaa aggacggatt
     8401 ttgctatgta gatcagatat tgagcctgga gatagtgtga gaattcctaa cgtagagtat
     8461 tggaaaattc agtacgacaa tgcgagtggc tggttacgtt atggaaatgt cactgatcta
     8521 agggggataa catatgttga aatttttcaa aatgaactgg ttggtcttaa ttcagatggg
     8581 catattgaag agatatggct gaagcctgta tggttatagt cattttctgt gcaaaggtta
     8641 tttgaagact ggaaatttag ttaagcttaa agtagctatt aaaaagcaga tcttaaatat
     8701 tttaaacaaa cttgtttagt aatagtaatt tagtttttag aggatatagt taaataaaaa
     8761 agtgataact tctttttgtg atgtaggata gctaggcaaa gagtaaaaat tttcctaaag
     8821 ttgtctaata aaaattgttt ctagtaaaaa tgttccttgg gttatttcgt caaaatagac
     8881 tgcctcacag gctaattgtt ggtagaaaat agaaatgggt tatgataatg cactgtataa
     8941 accaagaact ccagtgtatg aaatagaatt atcagaggat actatgtttg tttgagtata
     9001 tgctggtgag gtttcagatc aatttgtgaa gt
//
LOCUS       DARYSY010000068         8944 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYSY010000068 DARYSY010000000
VERSION     DARYSY010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8944
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            93..4304
                     /locus_tag="TVR04_001720"
     CDS             93..4304
                     /locus_tag="TVR04_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding adhesin SdrG C-terminal
                     domain-containing protein"
                     /protein_id="HEL1270392.1"
                     /translation="MMKKRKLLSLVATTGLLFAQFLTPLGQIGALMGYADAKNSITEV
                     VTDGLNNRQTADLPQSETAASKLEETASPAPTTSGDDKSENTTKKSPLELQPRALRVA
                     DDLLTRTGSFKVKKVDEDGKTLLGNAKFRLMSDSTNTPVYQTELTTSIAGEATFSNIP
                     PGTYLLKEIHAPSGYQEMTDCYKITVSQDGYTQYTYVKTSVGTEVIPSVAPSTGEAGS
                     TEVRAPKTSGVVTVENYQFTTKNKASGNADYKKLWATSGEFFDMSFTLKVKEGTQPGD
                     SFTIKLSPYLSPNGIREKFISAPPLMLDNQVVATGIYDEKENSYIYTFNDLITRKKNI
                     TLTANYTFSPEAKKVDREWYINTYNITNVIDEQKQDSGDFTIDYGEGQYMAGVLNSGL
                     RLRNNVTYLNRTTGEVEYTIYLNNGASPRDSKYTVSDPWVALHYVNVSEKSSAVLFNK
                     DDITVYRVPLSQKTSKMPYSMSGETDGLEIISVNHDNQGFSLPKGSFYDSETKKNTAG
                     ILIKIKAKIDSPIRTADVSLNAIWKYTQVGGQSNAKASAIELGNTSSGSANNIEPTLT
                     IRNYKKKKGSIAFTKQDSEEKTALKDVTFKLEKKAGDQWHVVDKYKEVKSETDGKLSL
                     IDLDPGEYQLIETKPLDGYLIPSGPVATFTITDQGTEDAVKPSDKVIQNTKPGHQKIK
                     VVKKDEQSSTPLSGATFQLESSKGVVLTGETNQKGEYTFKDLPFGEYLLTEIRAPKGY
                     ILDKTPRTIIVGETSNDMAPSTVQPRSVEFRSAPAALTTGKDVSDNIVVKKVEYSSTN
                     GQEFLNVNPNHGENLIARTEFELKKEIKIQKGDYFAVKLSENIDPFGIATGETTSFNI
                     VGTYGILAVGKYDNNSRSIIYTFTDYVEKYEVSRFSTILPYFIDRYTVKRDQDIVVST
                     SVSNQEYSTNVRVLYTPYYGATDSYSPVNIGSMLTKLDLKQELFTNYVYINPRHESIR
                     NGELYFIGDGSAIINEETSVTLFKAHYNENMPPSWGVNDADLTEEVNIPIVKKNGQIY
                     INFGNNLQYRDSFVMKVVGRYDTDSDVPIKTSATLYQNYYNYYGYYTENGRWIPQGPY
                     SEYFTYNAGAVLKSGESSADGAIRVSVTNRKNSVAFTKTNGLEKPLEATFELRRLNSN
                     KTFTSVKTTTSTKDTGTFSFEGMEAGSYEVWETQSPEGYLKPDKAVATFKVDKDGTIK
                     DLTPDNGKIINYPNTAKIIFTKMLASEKGELSPATKEKSATFSLWRLKEENLKETNTI
                     NQAYDEQHYEPVIDNNSVRTVTSDSRGNVLFDKLSPGFYAIKEEKAPDGYVKQQGIVR
                     IFQVDSAGKVIKYQYSKDKSIADKLTEITALETEQLKQFDEIVNKQFVFPMTGGQGVA
                     LFVMIGGAMMGIAYLGHRRKQKLNS"
     gene            4428..6539
                     /locus_tag="TVR04_001721"
     CDS             4428..6539
                     /locus_tag="TVR04_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270393.1"
                     /translation="MKTKIFSILAAVLLVLGSLLPTLVTVAEGESPHQTDIVIHKIKM
                     TSLVGWPKEKNPDGTYTGDNNQNYNGEKINTITSYFGAGAEELDGVSFTYWKVGKKED
                     YEKLVKDPQSYNTVAKVKGLLKDVTEKQTGATAGQAGVKVEHLEDGYYWFVENTGSLI
                     ANGETLSSGAAVPFSLELPVYKADGSTIKELHVYPKNTTTKPKIDKNFSNEEKDAKLA
                     GGANYDYYQKDKGHVSRILGSEVSFQIKTEIPAGAQYQTLRWEDTMTKGLTYKVGSLE
                     LQITANGSKFSFDGLDYTIFENQSGFALLFTPEGLEKVKKAVQATKNDKGQIADDGNP
                     MTIELNYKAIVNSDAVVDQFDQNTVVFDYGNNPKAYKDPRDKSTKPKDKSITVNKTWA
                     TQPAPSGVEVTYYLYQKGTTANEDKVVDSVILTKDYHHTFTNLDDSKEYYVKESAIGY
                     IPEYTSAQGGTISIKNTKDDKNPDPLKPTSPAIVTHGKKFVKTSQEDERLQGAAFVVA
                     NQKTGGKYLAIKADNEQNAEEKAYQEAEKKYQEEIKKATTGKPNTLEIEKAKKARDDA
                     FKKARTAYQWVDDKEKAIKLTSNSKGQLELTGLAAGTYYLEELTAPIGFAKLQERVEF
                     KLGFNSYHGHKDSSGQSLEDHIQYEKGTPDFGYAQRVINKKITIPQTGGIGTVIFTIA
                     GLAIMIGSGYVMVRRHRNDKA"
     gene            6544..7416
                     /locus_tag="TVR04_001722"
     CDS             6544..7416
                     /locus_tag="TVR04_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEL1270394.1"
                     /translation="MTITTKGGRQLEKSRWLQFILSVCTCLCFLTPPVFAVTKTSSIT
                     IRLEKSSEDTHLSLWSLPKDKALPELATLFSLTDADVTKQYPKVFTAVLPKGETDLVL
                     VDLPVGASYYVREAESEHKEHVLAPFIVTVKASDDQVIYAKDITPQKRGSYPFVKLSS
                     QGGTLEGATFEVWRQSKDKASPVLKKGKTYLVASNSKGFFEVQDLPFGSYYLKEVKAP
                     KGYLLSQKKIFFEVTNYSAKAAPTKIINAAKTPPRIEVPYTGNAVMIIVVLIGFVMFI
                     LGFYFVHQDSKKDS"
     gene            7505..8149
                     /locus_tag="TVR04_001723"
     CDS             7505..8149
                     /locus_tag="TVR04_001723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270395.1"
                     /translation="MKLVKRLIPICLAIFWGSLSIPKTVAANQVFKAEHQQPLAETTV
                     KAFKVGDQAITIQTPAHWYAYVYVNNNLVTQAVKTIERPCVHHVEDGCVSNSYLYSGY
                     RTGYNGSYTVKLPKALEASDTIKVSFSNDDNFYYGDLIYTIPKVEVSQAITTISNPTE
                     EAGQESQIIPTEETYQLYKTYLDYEARKSWQHKVSDFFGHQWANLKSWWQDMKS"
     gene            8152..>8944
                     /locus_tag="TVR04_001724"
     CDS             8152..>8944
                     /locus_tag="TVR04_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1270396.1"
                     /translation="MGKNKKEAALSDKKQSSLICKQSKWYRFKRNAPLVFIFLIGLAI
                     LLYPQLSRIYYTIDSNNQAKYFDRDKSQLDQADIEKRIALAKAFNASLHDVSLRDPYS
                     DEQKKAGRTEYARMLELHEQMGHVEIPKIKMDLPIYAGTSNEVISKGSGHLEGTSLPV
                     GGKNTHTVLTSHSGLPSAKLFSDLSKVKKGDIFYIHNIKEILAYQVDQIKTIEPDNFS
                     DLLIVPKKDYATLLTCTPIGINTHRLIVRGHRVPYRAKEHKKAQEE"
BASE COUNT         3046 a         1482 c         1903 g         2513 t
ORIGIN      
        1 tttggttgtt accaaaaatg acagtcgtag atataagggg ataggtaaat tggtaagcac
       61 tatataggaa gagagaggcc tacaaacaat ttatgatgaa aaaacgaaaa ttacttagcc
      121 tagtagcgac tacggggctt ctttttgcgc aatttttgac accattagga caaattgggg
      181 cattaatggg atatgctgac gcaaaaaata gtattacaga agtagttact gatggtctta
      241 ataatcgtca gacagcagat ttgccacaat ctgagaccgc tgcttctaag cttgaggaaa
      301 cagccagtcc agcaccaact actagtggag acgacaaatc agaaaatact actaaaaagt
      361 ctcccctaga acttcaacct agagcgttaa gagttgccga tgatttgcta actagaacag
      421 gaagctttaa ggtaaaaaag gttgatgaag acggtaagac actgcttggt aatgctaaat
      481 ttcggttaat gtcggatagt accaatacac cagtctatca aactgaatta acaacgagta
      541 ttgcagggga agcaacattt tcaaacattc caccaggaac gtatctttta aaggagattc
      601 acgcaccaag tggttatcaa gagatgactg attgttataa gataacagtt agtcaggatg
      661 ggtacacaca gtatacttat gtcaaaacga gtgtgggtac tgaagtgatc ccttcagtag
      721 ctccttcaac aggtgaagct ggatcaacag aagtgagggc acccaaaaca tcaggggtgg
      781 tgacagtaga aaactatcag tttacaacta aaaataaagc aagtggtaat gctgattata
      841 aaaagctgtg ggcaacctct ggggaatttt ttgacatgtc cttcaccttg aaggtcaagg
      901 aaggaacaca acctggtgat tcttttacga ttaagctaag tccatattta tcgccaaacg
      961 gtattcgtga gaagtttatc tcagcaccac cgcttatgct tgataatcaa gttgtcgcta
     1021 cagggattta tgacgagaag gaaaatagtt atatttatac ttttaatgac ttaataaccc
     1081 gtaaaaagaa tataacccta actgccaatt atacctttag tccagaagct aagaaggttg
     1141 acagagagtg gtatatcaat acctataata ttacaaatgt gattgatgag cagaaacaag
     1201 attctggtga ctttactatt gattatggtg aaggtcagta tatggccgga gttctaaata
     1261 gcggactacg attaagaaac aatgtcactt atcttaatcg gacaactggt gaagttgagt
     1321 acaccattta tttgaataat ggagcatcac ctagagatag taagtatacg gtatcagatc
     1381 catgggtagc attacactat gttaatgtat cagaaaagtc tagtgctgtt ttatttaata
     1441 aagatgatat cactgtttat cgagttccat taagtcaaaa aacgagcaag atgccttaca
     1501 gtatgtcagg tgagactgat ggattagaga ttatttccgt taatcatgat aatcaaggtt
     1561 tctctttgcc aaaaggtagt ttctatgatt cggaaactaa gaaaaatact gctggaattt
     1621 taatcaaaat aaaagctaaa attgattctc cgattagaac tgcagatgtc tctttgaatg
     1681 ctatttggaa gtatacgcaa gttgggggac agtcaaacgc caaggctagt gccatcgaat
     1741 taggaaacac atcttctggg agtgctaata atatagaacc aaccttaact attcgaaatt
     1801 ataaaaagaa aaaaggatca attgctttta cgaagcaaga ttctgaagag aaaactgctt
     1861 taaaagatgt cacctttaaa ttagagaaaa aagcaggtga tcaatggcac gttgttgaca
     1921 aatataaaga agttaagtct gagactgatg gtaaattatc tttaatagac ttagatccag
     1981 gagaatatca attaattgaa acaaagcctt tagatgggta tttgatacca tcaggacctg
     2041 tggcaacctt taccataaca gatcagggaa cagaagatgc ggttaagcca tcagataaag
     2101 taatccaaaa tactaaacca ggtcatcaga agattaaagt cgtcaaaaag gatgagcaaa
     2161 gctcaacacc attatcagga gctacatttc aacttgagtc aagtaagggt gttgtcttaa
     2221 ctggtgaaac aaatcaaaag ggagagtata cgtttaaaga tttgcctttt ggagaatatt
     2281 tattgacaga gattcgtgca cctaagggat atattctgga taaaacgccg cgtactatta
     2341 tagttggtga aacgtctaat gatatggcac cttctacggt acaaccgaga tcagttgaat
     2401 ttagaagtgc tcctgctgca ctgactacgg gtaaagatgt ttctgataat atcgtggtta
     2461 agaaggttga gtacagttct acgaatggtc aagagttttt gaacgttaac cctaatcatg
     2521 gtgaaaacct gattgctagg actgaatttg aactgaagaa agaaataaag attcaaaaag
     2581 gtgattattt tgctgtcaag ctttcggaga acattgatcc ttttggtatt gcaactggag
     2641 agacaactag ctttaatatt gttggtactt atggaatatt agcagttgga aagtatgata
     2701 acaatagtag gagcattatt tataccttta cggattatgt tgaaaaatat gaagtatcac
     2761 gtttttcaac catattgcca tactttattg accgttatac tgttaaaaga gatcaagaca
     2821 ttgttgtttc aacaagtgtt tcaaatcagg aatattcaac caatgttaga gtgctctata
     2881 ctccttatta tggagctaca gatagttatt ctcctgtaaa tatcgggtca atgttaacaa
     2941 agctggattt gaaacaggaa ttgtttacca actatgtata tattaatcca aggcatgaga
     3001 gcatacgtaa tggtgagtta tattttatag gtgatggttc tgctattata aatgaagaga
     3061 cgagcgtaac cctttttaaa gcacattaca atgaaaatat gcctccaagc tggggggtaa
     3121 acgatgctga tttaacggaa gaagttaata ttcctattgt taagaaaaat ggacaaattt
     3181 atattaactt tggtaataac cttcaataca gagattcatt cgttatgaag gttgttggtc
     3241 gttatgatac tgattctgat gtgccgataa aaactagtgc gacattgtat caaaactact
     3301 ataactacta tggttactat actgaaaatg gacgctggat acctcaagga ccatattcgg
     3361 aatactttac ctataatgcc ggagctgttt taaaatcagg cgaaagtagt gcagacggag
     3421 ctattagggt atcggtgact aatcgtaaaa atagtgtagc atttactaaa acaaatggtt
     3481 tggaaaaacc gttggaagct acctttgagt tacgccgatt gaattctaat aagactttta
     3541 cttctgtgaa aacaacaacg tcaactaaag atactggtac atttagcttt gaaggcatgg
     3601 aagctggaag ctatgaggtt tgggaaactc agtcaccgga aggttatctg aagccagata
     3661 aagcagtagc tactttcaaa gttgataagg acggtacaat taaagatttg acacctgata
     3721 acggtaagat tattaattat cctaatactg ctaagattat ttttacaaaa atgttggctt
     3781 ctgaaaaagg ggaattgtct cctgctacga aagagaagtc tgcaacgttt agtttatggc
     3841 gacttaaaga ggagaatttg aaagaaacta atactataaa tcaggcctat gatgagcagc
     3901 attatgagcc agtgatagac aataatagtg ttcggacagt aacctcagac agtagaggaa
     3961 atgttttatt tgataagctt tctccaggtt tttatgccat taaggaagaa aaggcgcctg
     4021 atggctacgt taagcagcaa ggaattgtgc gcatcttcca agtagatagt gctggcaagg
     4081 taattaagta tcagtattct aaagataagt caatagctga taagctaaca gaaataacag
     4141 ctttagaaac agagcagcta aaacaatttg acgagattgt taataaacag tttgttttcc
     4201 ctatgacagg tgggcaaggt gttgcactat ttgtgatgat tggtggtgct atgatgggga
     4261 ttgcttatct tggtcatcgt agaaaacaaa aattaaatag ctgacgattg ctatttgatt
     4321 gctgcaggag agctcccttt tgagaaaagg gatggcagat aacttaacaa tcaaaaaaga
     4381 attgaaaaac acttaggcaa atatttttta caaacaggag agaacagttg aaaacaaaga
     4441 tatttagtat attagcagca gtattgctgg ttttgggaag tcttttaccg acactggtaa
     4501 ctgtggcaga aggagaatca ccacatcaaa ctgatattgt tatccataaa attaaaatga
     4561 caagcttagt tggctggcct aaggaaaaaa atccggatgg aacgtacact ggagataata
     4621 atcaaaacta taacggtgaa aagattaata caataacaag ctactttggt gctggtgctg
     4681 aggagcttga tggtgttagc tttacttact ggaaggtagg gaaaaaagaa gattatgaga
     4741 agctagtaaa agatcctcaa agctataata ctgtagcaaa agttaaaggt ttactaaaag
     4801 atgtaacaga gaaacagaca ggtgctactg caggacaagc tggcgtcaag gttgaacatc
     4861 ttgaagatgg ctactattgg tttgttgaaa atacaggatc attaattgct aatggtgaga
     4921 ccttgtcttc aggagctgcg gtaccattta gcttggagtt accagtttat aaggctgatg
     4981 gctcaacaat taaagagctg catgtgtatc ctaaaaacac cacaacaaaa ccaaaaattg
     5041 acaaaaactt tagtaacgag gaaaaagatg caaagctagc aggcggagct aattatgatt
     5101 attatcaaaa ggataaaggt catgtatcgc ggatacttgg ctcagaggtt tccttccaga
     5161 ttaaaacaga gattccagcc ggtgcacagt atcagaccct tcgctgggaa gataccatga
     5221 caaagggctt gacctataag gtaggaagct tggagttaca aatcacagca aacggttcaa
     5281 agtttagttt tgatggctta gattatacta tttttgaaaa tcaaagtggg tttgctttgc
     5341 ttttcacccc tgagggctta gagaaggtta aaaaagctgt tcaagcaact aagaatgata
     5401 aggggcaaat cgcagatgat ggtaacccaa tgaccattga gctcaactac aaagccattg
     5461 taaatagtga tgctgtggtt gatcagtttg atcaaaacac cgttgtcttt gattatggta
     5521 ataatcctaa agcgtataaa gacccaagag ataagtcaac aaagccaaaa gataagtcta
     5581 ttacagttaa caaaacatgg gctactcaac cagcaccgtc aggtgttgaa gtgacctact
     5641 acctttacca aaaaggcacg acagcaaatg aagataaggt agttgattct gtcatattaa
     5701 ccaaggatta tcatcatacc tttacaaact tagatgattc caaggaatac tatgtcaaag
     5761 aaagtgctat tggttacata ccagagtaca cttcagctca aggtggaaca atttccatta
     5821 agaataccaa agatgataaa aatccagatc ctcttaaacc gactagtcca gcaattgtaa
     5881 cacatggtaa aaaattcgtt aagacaagtc aagaagatga gcgtctacaa ggtgcagcct
     5941 ttgttgtagc taatcaaaaa acaggtggta agtatttagc cattaaagct gataatgaac
     6001 aaaatgctga agagaaagct tatcaggagg ctgagaaaaa gtaccaagaa gagattaaga
     6061 aagcgactac aggcaagcct aatacattag aaattgaaaa ggctaagaaa gcgcgtgacg
     6121 atgccttcaa aaaagcaaga actgcttatc agtgggtaga tgataaagaa aaggccatta
     6181 agttgacgtc aaacagtaaa gggcaactgg agctaacagg gcttgccgct ggcacctact
     6241 atttagaaga attgacagct cctatcggct ttgcaaagct tcaagagaga gttgaattta
     6301 agcttggttt caactcttat catggtcata aagattcatc tggccaaagc ttagaagatc
     6361 atattcaata tgaaaaaggt acacctgatt ttggctacgc gcaacgcgtc atcaacaaaa
     6421 aaatcactat tccccaaacg ggtggtattg gtacggtcat ttttactata gctggtttag
     6481 ctattatgat aggatcgggt tatgtaatgg ttcgtcgtca taggaatgat aaggcttagt
     6541 tgcttgacga taacgactaa aggaggtaga caattggaaa aatcacgctg gcttcagttc
     6601 atattgtcag tttgtacatg tttgtgcttt ctgactcctc cagtttttgc tgtaactaaa
     6661 acatcatcaa taactattcg tcttgaaaaa tctagtgagg atactcatct atctctatgg
     6721 tctttgccta aggataaggc tttgcctgaa ttggctacgc ttttttcctt aacagatgct
     6781 gacgttacca agcagtaccc taaagtgttc actgcggtat tgccaaaggg agaaacagat
     6841 cttgtgctag ttgatttgcc tgtaggggct agctattatg tccgagaggc agagagtgaa
     6901 cataaagagc atgttcttgc ccccttcatt gtaacggtta aagcaagtga tgatcaggtc
     6961 atttatgcta aagatataac accacaaaag cgtgggtctt acccctttgt aaagctttct
     7021 tcgcaagggg gaaccttgga gggggcgacc tttgaagttt ggcgtcaaag taaggataaa
     7081 gccagcccag ttctaaaaaa gggtaagacc tatcttgtag cttcaaatag taaaggcttt
     7141 tttgaggtcc aggatttacc ttttggtagc tattacctta aagaagtgaa ggctcccaag
     7201 ggatatctct tatcccaaaa gaaaatcttt tttgaagtaa ccaattattc tgcaaaggca
     7261 gcaccaacta aaatcattaa tgcggctaag actccgccta gaattgaggt gccttatact
     7321 ggaaatgctg taatgattat tgttgttttg attggctttg tgatgtttat acttggattt
     7381 tactttgtac atcaagatag taagaaggac tcctagatcg tgagagagct agaggtatcc
     7441 agcctattga gacagggtgc ttctagttct ttttaactaa ataagaatta gaaagaaaat
     7501 tacaatgaaa ctagtaaaac ggttgatacc tatttgtcta gctatttttt gggggagctt
     7561 aagcattcct aaaactgtag cagctaatca agtatttaaa gcagagcatc agcagccctt
     7621 ggcagagact actgtaaagg catttaaggt gggggatcaa gcgataacta tccaaacacc
     7681 ggctcattgg tatgcttacg tatatgtgaa taacaactta gtcacacaag cagttaaaac
     7741 aatcgagcgt ccatgtgttc atcatgtgga agatggttgt gtgtctaata gctatctcta
     7801 tagtggctat cgtacaggct acaatggttc ctataccgtt aaactaccga aggccttaga
     7861 agcctcagat accattaaag ttagcttttc taatgatgat aatttctatt atggggattt
     7921 gatttataca attcctaagg tagaggtatc acaagcgatt acgactattt caaatccaac
     7981 cgaagaggct ggccaagagt cacaaatcat tcctaccgag gagacttatc agctttacaa
     8041 gacttattta gattatgaag cacgtaagtc ttggcagcat aaggtcagtg atttttttgg
     8101 tcatcagtgg gcgaatctta agagctggtg gcaggatatg aagagttaaa tatgggtaaa
     8161 aacaaaaaag aggctgcctt aagtgataaa aagcaaagct ctttaatctg taaacaaagc
     8221 aaatggtatc gttttaaacg taatgcaccg ttagtattca tatttttgat agggttagct
     8281 attcttctct acccacagct ttctcgtatt tactacacta ttgactctaa taatcaagct
     8341 aagtactttg atagggataa gtctcagctt gatcaggctg acattgaaaa gcgcatagcc
     8401 cttgctaaag cctttaacgc aagtcttcat gatgttagcc tgagagatcc ttactctgat
     8461 gagcaaaaaa aagctggtcg gacagagtat gcgcgcatgc tcgaactcca tgagcaaatg
     8521 ggacatgtag aaattcctaa aattaagatg gatttaccga tctatgcagg aacaagcaat
     8581 gaggttatat cgaaaggaag tggtcatctg gaagggacct ctttgccagt tggtggaaaa
     8641 aacacacata ctgtcttgac ttcacattct ggattgccgt ctgccaagct cttttcggat
     8701 ttatctaagg ttaaaaaagg ggatattttt tatattcata acattaagga aatcctagct
     8761 taccaagtag atcagattaa aacgattgag cctgataatt tttcagattt attgattgtg
     8821 cctaaaaaag attacgctac ccttttgacc tgtactccaa ttgggattaa tacgcatcgc
     8881 ttaattgtac gaggacaccg cgttccttat agggcaaaag aacacaaaaa agcgcaagag
     8941 gaaa
//
LOCUS       DARYSY010000069         8811 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYSY010000069 DARYSY010000000
VERSION     DARYSY010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8811
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(11..373)
                     /locus_tag="TVR04_001725"
     CDS             complement(11..373)
                     /locus_tag="TVR04_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1270397.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHREYQAQM
                     DYAKAQLMAEMVYQEQPPSDGQIAFNCGQASYKSHKQRFIIEIKLPHQQLYQFSYPKV
                     QQVSQTSKKEPELKQSLP"
     gene            complement(351..785)
                     /locus_tag="TVR04_001726"
     CDS             complement(351..785)
                     /locus_tag="TVR04_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1270398.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMVSERYLAA
                     NDQDNWLLFSQQLRAELSGTTLQGIRNNRLYVEKDKKALSFGQVKGHDFRKAAGNGRG
                     YQPMLFGLSSSQITAVGQQVIIKLKWQSGLERTFIYAFQEKG"
     gene            complement(772..1062)
                     /locus_tag="TVR04_001727"
     CDS             complement(772..1062)
                     /locus_tag="TVR04_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1270399.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALHYSQQELSAC
                     RQKQELLNTAVMAIQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1019..1444)
                     /locus_tag="TVR04_001728"
     CDS             complement(1019..1444)
                     /locus_tag="TVR04_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1270400.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLCLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1422..1745)
                     /locus_tag="TVR04_001729"
     CDS             complement(1422..1745)
                     /locus_tag="TVR04_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1270401.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDRQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1746..2732)
                     /locus_tag="TVR04_001730"
     CDS             complement(1746..2732)
                     /locus_tag="TVR04_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1270402.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLPPVYV
                     TNMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNALTDLLLHLPHYFLGFCLLLLSL
                     IGSFYLYARSCSRLRLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFRKELSLMIEYGDIKSKLGRELD
                     IYAQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQHMGDVF"
     gene            complement(2713..3651)
                     /gene="tadA"
                     /locus_tag="TVR04_001731"
     CDS             complement(2713..3651)
                     /gene="tadA"
                     /locus_tag="TVR04_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1270403.1"
                     /translation="MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDKRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDGTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVTYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3808..4476)
                     /locus_tag="TVR04_001732"
     CDS             complement(3808..4476)
                     /locus_tag="TVR04_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270404.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKLSKEEGQQRELEVLKAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHENRTIIIATHNPSIWEMADEVLSVDQLSLPKLQIKH
                     GLAK"
     gene            complement(4478..6088)
                     /locus_tag="TVR04_001733"
                     /pseudo
     CDS             complement(4478..6088)
                     /locus_tag="TVR04_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(6116..6481)
                     /locus_tag="TVR04_001734"
     CDS             complement(6116..6481)
                     /locus_tag="TVR04_001734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270405.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVE"
     gene            complement(7028..7393)
                     /locus_tag="TVR04_001735"
     CDS             complement(7028..7393)
                     /locus_tag="TVR04_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1270406.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQTSLSCKLGI"
     gene            complement(7454..8500)
                     /locus_tag="TVR04_001736"
     CDS             complement(7454..8500)
                     /locus_tag="TVR04_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1270407.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFTQMLKTYLLWSLIYFPYAYAFF
                     ESLHLPKHYLPLGLCLALGYFGMCYHLWYIPALWLGWVLVQLSLKTFGQKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMYIFQTSRNGIFYTPAYLCAGCLLYDHFSSVL
                     FSQRYMKKAALCLILLTLESLLIYHHQGLDKNFFLLSALFTTFLFNASVRTSLLSKYS
                     LAKLKKLSYYYFFLHPMFIESSLFLLKPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
BASE COUNT         2759 a         2004 c         1626 g         2422 t
ORIGIN      
        1 gctcccttag ttatgggagt gattgcttaa gctcaggctc ctttttagaa gtctgagaga
       61 cctgctgaac tttaggatag ctgaattgat ataactgctg atgtggtaat ttgatctcaa
      121 ttataaaacg ctgcttatgc gacttatagc tagcctgacc acaattaaag gcaatctgac
      181 catcgctagg aggctgctcc tgatagacca tttctgccat tagctgagcc tttgcgtagt
      241 ccatctgagc ctgatattcc cgatgtagct ggctaatatg actaagataa gcctgtaaca
      301 gtaataaaaa gactgatgcc atcagcaaag catacaaaag cactcctgcc ttaacccttc
      361 tcttgaaatg cataaataaa ggtcctttct aagccgcttt gccatttcag cttgatgata
      421 acctgctgac ctactgctgt tatttggcta cttgacaagc caaacagcat gggctgatag
      481 cctcgaccat tgccagctgc ttttctaaaa tcatgaccct tgacctgtcc aaaggacaaa
      541 gccttcttgt ccttttcaac atatagccta ttattgcgga taccctgtag ggtagtacct
      601 gaaagctctg ctcgcaattg ctgggaaaac aaaagccagt tgtcctgatc atttgctgct
      661 agatacctct cactcaccat aaggctctta gttaaggcct gataaactaa taaagagcct
      721 gagatgacaa gcaaggcaat aaggcactct atcaaggtga aagcctttaa cctactgtct
      781 ttcaatccta ataatcgttt ggtctttttc aacaatagcg atacccttct gatgtgataa
      841 tagcttaata tgacaaccat taaggcttaa tgctctttgt tttgtctgta tggccatcac
      901 agctgtattc aacagctctt gcttttggcg acaggccgac agctcttgct ggctataatg
      961 cagggctgac aggatcagtg ttacaataac aagaataagt cctgtcgcta tcaagccttc
     1021 aagagcgatg taggctttga cttgtttttt gataattacc actccctaaa taaaattgat
     1081 aagtaatctg ccgatctcta ttttcaaaga caacccttgc cagcgaatga ttgccgccca
     1141 gtttatcaat ggttaaggtc tgggtagatt ttagcttgac ctgctttggc agaggcaaaa
     1201 tagcttcttc ggccttaata taatgtggct ttaagaccag cacatgctct ttttgacgta
     1261 atatcgatag cttctgcagg tgcctatagg cctgttcaaa gcgcatgaaa aagagatgct
     1321 cctcaaccct agcatagcta tctgataccg gtagtgacaa gcacagcagc ataaagctaa
     1381 tcagaaaaag cgtcaataag ccctctaaga gggtaaaagc tttaattgag cttcttagct
     1441 tcatctttat gctttgcata ataatcctga taagcctttt gttgcctgtc actgatgctt
     1501 ccatcctctt gcagctgctt taggcttggc ttttccccat gtgataattc ataaagctct
     1561 gcctgatttt caactagctt taccactgca gcgttgcctg tatctgtcac cttatccttt
     1621 tgcttactta aatttggaac aaataacagc atcagaacac taatgattaa caaaaccaga
     1681 agcatttcca gcaaagtgaa ggcctgaaca ccttgatctt ttaagattga taatctcatt
     1741 ttcatttaaa aaacatctcc catatgttga taaattggta ataaaatagc agcataaatc
     1801 atcacaataa ccacagcaac cactaaaaaa ataatcggct ggatccattg tgttgcccga
     1861 ttgagctgac taaaaaaggt ctcccagctt tcttgggcat agatatctag ctcccgacca
     1921 agctttgatt tgatgtcgcc atattcaatc attaggctta gctcctttct aaaaaaggga
     1981 taagctgcaa ccctttgatg aaaggattgg ccagctagta gactctgctt gatatccttg
     2041 gcaagctctc gcatgagctg tgacttttcg tttgacatca tttctaaaat ggtgattaat
     2101 tctaagcctt gtccgatgag gttgccccat tctctagcat agtaggctgt caaatattgc
     2161 cgcaataagg acccaatgat aggataatag ctcagctgac taaatagcct taacctgcta
     2221 caggacctgg catataggta aaaagagcca atcagcgaca gcaaaagcag acaaaagcct
     2281 aagaaataat gaggcaaatg aagcaacaag tcagtcaagg cattttgact ctctagctga
     2341 gggattaggt aatgccgcaa gcctagcatg ataaccacta aaaaacctaa aagtatgatc
     2401 ggatacgtga ctgcctcgat ggtctttcgc ttgatttggc gaaattgact cagataatcc
     2461 tgaatttttt ccaaggttag cttgatattg ccatgcttat ctgctagatt aatttgtgtc
     2521 atgacagcat cagagtagcc taaggctgcc agcatatcag caaggccatt gccctttaat
     2581 aggcttgctt ccatatttgt aacatagact ggtggtaaca gctggctttt tctcaaaaaa
     2641 gcaatgacct ctgttaaatt aaaaccgtta gacaataggt tatagagcaa ttggataagc
     2701 ttttcttgct gcttactgga taattttttc aagccttgcc tgcctggtat tgagatgtcc
     2761 ctctgcaaga agctgatcaa tctgctgatt ccaccggttg gcttgatgat gttcaaattc
     2821 cttttgtgca caatcaatta aagcacctcc actaataaat cgctggtaag taaccattgc
     2881 tagactatta tccaattctg ccctagaaat gcctaattct agcagcctag cgtaaacgcc
     2941 tgaaatactc tttgcatgga cggttgaaaa gaccattgct cctgttaggc tagccctaat
     3001 aaccgctcta gcagtctgtg tatctctaat ttctccgata atcaacacat ctggacgatg
     3061 acgcaaggag agcttaatca gattatcgta tgtcatgcca atgctgtcgt taacctgtaa
     3121 ttgcaggagc tgatcatttt taatttccac aggatcctca atactgatca cctgaagctc
     3181 cttgcaatag tcagagacta gctgatacat cagggttgtc ttacctgatc caaccggtcc
     3241 agaaaagagg taaaggcctc tggctccaat agctgatgtg actcgctcta aaccatcaaa
     3301 ccaatacctg agctggcgtt gatgatgata caagagacga ataaccaagc tctcctgtcc
     3361 ctgatagtca cccacagctg ataatcgtag agatacctta gtgccatcaa ggtcgtagtc
     3421 acaagcaccg agctggcagc gtcttttttc tcccacattc attcctgcaa cgaacttaaa
     3481 gtgactaata agattagcca tccgatcact ttcacaaaca tctattagcc tcttgtcatc
     3541 acctatcctc atcaaaagct catagcttgc ccctcttggc agtatataaa tatcctgagc
     3601 ctgcaattct tcggcctgcc tgataagcct cttggctaat tcttgaacca ttcttacctc
     3661 ctcactaaga ctattcgaaa aataaaaaaa atagcctcaa gaaaaaggcc attttttgat
     3721 aaatgtttaa catcaagtaa ggaattcagc acgctataac agcgcagaat ctttttacga
     3781 tgctatgatg acaagatcaa gccttaatca cttagctagt ccatgcttta tttggagctt
     3841 gggaaggcta agctgatcaa cagagaggac ctcatctgcc atttcccaaa tgcttgggtt
     3901 atgggttgcg ataataattg tccgattttc atgtcgaagt gacaacaaaa tagccataat
     3961 tgccttagag gcctctggat caatagaagc tgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctaaggcaac acgctggtat tcaccaccag ataattcaaa
     4081 aacaggcttt tctaagctaa gataatccaa accaactgcc tttaggacct ctaattccct
     4141 ttgctggcct tcctccttgc ttaatttttg accaattagc cctagcttta aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccac ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaaa gcaaataacg acgatgcagc tcaaaaaatc
     4681 tgagaccaga aacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac acagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccatttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagtagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgcttcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggcgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggcag
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctctatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 ctttcttcgt atttccaata tctaagccat cacgtcatat taaaagagta accggcctat
     5521 cctcttgtcg ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gagtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctgatgat acctctaaca ggtatctgcc ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgctaggcta aggtcaagta gtaggcctag acagcaatag cacacatcag
     5881 atctgattgg ataaagaaag atctgccaac gacgttcacc tgaaatcaag cgaatacctg
     5941 ctgttctcag ggtacgaata tgacctatca aggccagggc tccaaaggtt agacagaata
     6001 tcacaagacc caaagcctga gaaccgctac taaaaatcag aaccacagtc cctaaaaatg
     6061 aaggcttcag cactgtcatt ttggtcatac caagcccagc taatgtgtct cttagtcact
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taagagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaaga tcattaattg aaaacgtccc ctcaatctct
     6721 tggatcaggt gaccaccacg ataccactca aatcattaac tctttaacaa aaatatacca
     6781 cattttgtta ccgtttacaa tgttgttttt aatccatttt tataaaaaac aacattatat
     6841 ctctaatgag tttatcataa taagctatcg ctatgctgtt ttctctattc caatcaagca
     6901 tcactagatt aaacatcttt ccagacaaca aaaatagctt aaaggcagct tcccttgatt
     6961 ggtcgccctt aagctatttg agtgataata aacataatgc ttgctttgac tgataggcat
     7021 aagcctctca gatgcctaat ttacagctaa gggaggtttg tgggcagtca tttctttgct
     7081 caaaatatga ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag
     7141 aatgatactg ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc
     7201 aaaaggtagc caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct
     7261 gccattcttc ctcaaaataa gctagtgcag caggccagct gtcaaacgat ttctcctgaa
     7321 caatatcgtc ttgccagcca tctataaacc accaaggctc ccagtctcca tacatttcaa
     7381 tcacttgata catgttctca tttcctctat tgcctattat agccgaagaa agatattttt
     7441 aaaaaacatc tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca
     7501 gcagcataag ggcctctgag caaagatgag tagctagcag agtcatgaga aagaccagtt
     7561 tcccttttgt ggcaggggca agctggtagg gctttagcag aaatagtgag gattcaataa
     7621 acattgggtg caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt
     7681 tagacagaag gctggtacga acactagcgt tgaataaaaa ggtagtaaac agcgcagaaa
     7741 gcaagaagaa atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggtca
     7801 ataagatcag acaaagagcc gcttttttca tataccgctg agaaaaaagc accgaggaaa
     7861 aatgatcata aagcaagcag cccgcacaaa gataggcagg ggtgtaaaaa atgccattac
     7921 gacttgtttg aaaaatgtac atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta
     7981 aaaaatgaga ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg
     8041 ttaccttctg accaaaagtc ttcagagaaa gctgaacaag cacccacccc agccataaag
     8101 caggaatata ccacagatga tagcacatcc caaaataacc aagggctaaa cacaagccaa
     8161 ggggaagata atgcttgggc agatgaagcg actcaaaaaa agcataagca taagggaagt
     8221 aaatcaaaga ccaaagcaaa taggttttta gcatttgcgt gaagtactgc ttttcccgat
     8281 tcgcctctct aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg
     8341 ccattcttcc taaaaagctt ttcaaaaaga aatgtagcgg ctcatactga aacagcctac
     8401 cgctatgaat aacaataacc attatggcaa agcagtattg taacaggctt accacagagg
     8461 tattgaggct gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt
     8521 aagagattaa tacacgcata actttagtgt ttatcgcatt tatctctcat tttgattaat
     8581 attgctttta ttatagcgta atatagccaa ttaatctaat gattttagca taacaaaagg
     8641 agctaagact agctcctgaa catcacaaaa gagaagacga ccttcatctc ctctcgttgt
     8701 tagctatcag tcacccacta cttttcttgg aatattttta tagacttttc ttacgaatat
     8761 agtaagaata accaccagta ataatgacat aattcaataa aagacaaaat t
//
LOCUS       DARYSY010000070         8242 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYSY010000070 DARYSY010000000
VERSION     DARYSY010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8242
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(366..662)
                     /locus_tag="TVR04_001737"
     CDS             complement(366..662)
                     /locus_tag="TVR04_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1270408.1"
                     /translation="MLTREEILNKVYNLILDPTLTSEERVILVRFKDRVGESNSFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKEFDKQLGRGLISLGVIRR"
     gene            complement(669..917)
                     /locus_tag="TVR04_001738"
     CDS             complement(669..917)
                     /locus_tag="TVR04_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1270409.1"
                     /translation="MNTTLMKQFEIIDTDKLAHVEGGGKGICKFVMAGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            1176..3332
                     /locus_tag="TVR04_001739"
     CDS             1176..3332
                     /locus_tag="TVR04_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1270410.1"
                     /translation="MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYIFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTKAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            3343..4701
                     /locus_tag="TVR04_001740"
     CDS             3343..4701
                     /locus_tag="TVR04_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1270411.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLTLLLTFLILFSCFAYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINGISQQIADYEELRAAVINQSNNLSSNNPHQATLDAY
                     LSQSQTDQEAATNQLLFQIDQSLLSLKASMDSLNKQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNRHITELKAQLEQATLQVNSLVIKAPKSGIVQLNSAFEGKTSIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSEYISLLKKNQIVRLALDSHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            4801..4935
                     /locus_tag="TVR04_001741"
     CDS             4801..4935
                     /locus_tag="TVR04_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1270412.1"
                     /translation="MDKPTRQSKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLEW
                     "
     gene            complement(5054..6388)
                     /locus_tag="TVR04_001742"
     CDS             complement(5054..6388)
                     /locus_tag="TVR04_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1270413.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLPKTLLIFYGLFPITLWSLWYRL
                     LGFFVVPLLGLNRHIINQSEWGIFTDIISTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVARLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNNDMSIVR
                     SVYQSVFKDSNKRFRKPKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEAI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFVIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(6388..7137)
                     /locus_tag="TVR04_001743"
     CDS             complement(6388..7137)
                     /locus_tag="TVR04_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1270414.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(7769..7972)
                     /locus_tag="TVR04_001744"
     CDS             complement(7769..7972)
                     /locus_tag="TVR04_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TmhB bacteriocin enhancer peptide"
                     /protein_id="HEL1270415.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCTVGAGQAIINGL"
     gene            complement(7989..8231)
                     /locus_tag="TVR04_001745"
     CDS             complement(7989..8231)
                     /locus_tag="TVR04_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1270416.1"
                     /translation="MNQFDVMNIKALATVEGGYSGKDCLKDMGGYMLIGAGSGALWGA
                     PAGGIGALPGAFVGAHVGAIGGGFACMGGMIGNRFN"
BASE COUNT         2749 a         1820 c         1273 g         2400 t
ORIGIN      
        1 gggggcattt catttgatag ctagtagcgc agatgatgtt tcttttccaa gctcaataag
       61 actcaaaatt aagttctttg taagaaaaaa ataaatcact aaccaaatga gataagctta
      121 ttgcccttgc aattatctca agctacttct tgtccgaagc caccctagat agttaactac
      181 cacaaaacaa taggtatcag ctttaaaccg atacctattg ttatatcctg cgattaacca
      241 atcaactcaa tcgttactta ctttaccttt agctagccat ctcacaaaat agcaataaca
      301 gccttttcat gtcgtttcgt ctattaacaa taacaccaat acaacaataa ggtatgagca
      361 ttttattatc gcctaataac tcccaatgat attaggcctc gacctagctg tttatcaaat
      421 tctttgtaag tagagatttc tttatagaat ttagccattt ctacactcat tgtttcaact
      481 cttatctgct taacagctaa ttgacgcaga gattcagaca gcatcatcac ttccctgtca
      541 aagctatttg actcccctac tctatcttta aatcttacca gaatgactcg ctcttctgat
      601 gttaaggtcg gatctaaaat taaattataa accttattta gtatctcttc tcgcgtcaac
      661 atacccaact accctctata gcctggatgg aaataaccac ctcctaaaga tgatatccaa
      721 ccattaacaa taacatcttt agttgcttca aaattacttt tagtaacaat atagccccat
      781 tcgccattgc tatatcgaca ggcataccca ttagaaccag ccattacaaa cttacaaatt
      841 cctttgcctc ccccctcaac gtgagcaagc ttatctgtat ctataatctc aaattgtttc
      901 attaatgtcg tattcatcgt gaatacctcc tatctttatt ttttgtctgt tgcaactgac
      961 aaacccagta tagcagataa acagctgctt tcaacgctta gtcctgaaat gtcgtcgaaa
     1021 cgtcttgaat ggtaatgtcg cagctgatta aaaaagagtg ttaatatcat tattcccatt
     1081 taagacgttt caacgactat tcaagactag ctcagttttt ttctgagctt ttgtggcaca
     1141 atagagtcgt tacaacagag aaaggaagcc aaccaatgac actcttttat aaaagaacct
     1201 ttgtaccaca aatagatgcc agagattgtg gcgtagctgc tctagcctca atcgcaaggt
     1261 attacggttc agattattca ttagctcatt tgagagaatt agcaaagacc aataaggaag
     1321 ggacaacagc tcttggtatt gtcatggctg ctaaggaaat ggggtttgaa accagaccta
     1381 ttcaagcgga tatgaccctc tttgacatgg cagacgtgcc ctatccattg atcgtccatg
     1441 tcaataaaga aggaaagcta cagcactact atgtggtcta caaatctaaa aaagactatc
     1501 ttatcattgg tgatcccgat ccaatggtca aggtcacaaa aatgtccaag gaacgctttg
     1561 cttcagaatg gacaggtgtc accatatgcc ttgctcctaa gccaaattat aaaccacata
     1621 aagaccaaaa aaatggacta ttaggcttct ttccgcttat ttttaaacag cgaaccctta
     1681 tattttatat cgtgttagct tctgtcttgg taacggtcat taatattgct ggttcatact
     1741 atctccaggg gattttagac gagtatattc caaatcagct gaaatctacc ttagggattg
     1801 tatcaattgg tctcatcatt acctatatac tccagcagct aatgagcttt tctagagatt
     1861 atcttttaac tgtccttagc caacgtctta cgattgatgt gatcctgtcc tatatccgcc
     1921 atattttcga attgccgatg tccttttttg caacacgtcg aacaggtgag gtaacctcgc
     1981 gctttacaga tgctaactct atcattgacg cactcgcttc aaccatttta tccctctttc
     2041 tagacctctc tatattagct attgtcggaa gtgttctttt ggtgcaaaat agcaggcttt
     2101 ttctgctatc tctgatttct atcccagtat ataccattat catatgtgcc tttataaagc
     2161 cgtttgaaca aatgaatcat gatgtgatgc aaagcaatgc catgctaagc tctgctatta
     2221 tcgaagatat caacgggatc gaaaccataa aatcactaac cagtgaagaa aaccgttacc
     2281 aaaaaattga cagcgacttt gtggattacc ttgataagtc ttttaagctt agtaaatata
     2341 ccatcttaca agccacactt aagcaaggag cgcagctaat tctgaatatc atcattcttt
     2401 ggtttggggc tcaactggtt attaatggta ggatttcaat tgggcagtta attaccttta
     2461 acacacttct tgcctatttt acaacccctt tagaaaatat cattaatctt caaaccaagc
     2521 tccaagcagc taaggttgcc aacaatcgtc tcaatgaggt ctatcttgta gagtccgaat
     2581 ttaaagcctc gcaagcctta tacgatttat cgctcttaca gggtgacatt cagtttgaag
     2641 ctgtttccta taggtatggc tttggcaagg atacattatc agatattaca ttaaccatta
     2701 agcagggagc aaaagtaacc cttgttggtg tcagcggctc aggaaaaaca accctagcca
     2761 agatgctcgt caatttcttt gaaccttata agggacgtat aaccatcaac caaaacgatc
     2821 tcaagaccat tgataaaaag aatcttcgac aatacatcaa ctaccttcca caacaagcct
     2881 atatctttaa tggatctatc ttagaaaatc taaccttggg agccaagcaa ggcatcagcc
     2941 aggaagacat tcttaaagcc tgtgagattg ctgacattcg tcacgacatc gagcaaatgc
     3001 caatgggata ccaaaccgag ctctctgatg gagctggctt atctggcgga caaaaacaga
     3061 gaattgcact ggctagagca ttattaacca aagctcctat attagttctt gatgaagcaa
     3121 ccagcggact tgacatactg acagaaaaga aaatcattga ccgtctcatg aacatgacag
     3181 acaaaacgat tattttcgtt gcccaccggc ttagtatcgc agagcgcact gatcaggttg
     3241 tggttcttaa tcaagggcaa atcattgaaa caggcagcca ccaggaatta atgaaacaag
     3301 gtggatttta ttaccaccta tttagtgaat aaggagacaa tcatgaatcc caatatgttt
     3361 aaaagtgcgg aattctacca aagacgctat catcatttga caacattctt aacaattccc
     3421 ttaaccctct tgttgacttt tcttatcctt ttttcttgct ttgcttataa agaaataacg
     3481 gtaacgtcct acggagaaat cactcccact caagtcattg caacagtcca gtctattagc
     3541 aataatccta taattgcgaa ccatctcacc aataaccagc caatcaaaca aggagactct
     3601 attattcaat atgctaaaga cctagaagag tctcaaaagc aggtacttga gaaacaatta
     3661 gctacctacg aaaagcaaaa aagcagcctt aatactctat tgttaagctt aaaacaaggc
     3721 cagaaccttt ttcagaacga tgatcaattt ggttacgtca atacctttaa tcatttcatg
     3781 agccaagccc aagatattga ccttggtttc tcaaaaataa aggcagagac cagccagcag
     3841 gcccagctga ttcaggactc tattgttgct atcaatcagc aaataaacgg tatctctcaa
     3901 caaatagcag attatgaaga gcttcgagct gcggtcatta accagtccaa taatctatcc
     3961 tccaataacc cacatcaagc cacccttgat gcctacctct ctcaatctca aacagatcaa
     4021 gaggctgcca ctaatcagct tctatttcaa atagaccaaa gccttttaag tctaaaagct
     4081 tctatggata gccttaataa gcaacgtgct aatctgcatc aatctaccag ctatgataac
     4141 agtctcaaca caaagctaga aatactccga acacagtttt tgataacagc ctctcagcag
     4201 ttaacagacg tcaatcgtca tattactgag ctcaaggcac aattagagca agccactctt
     4261 caggtaaaca gtctggtgat caaagcccca aaaagtggca ttgttcagct caatagtgct
     4321 tttgaaggca aaactagtat tccaatcggt catgacattg cctacattta tcctagcctc
     4381 aaacaaacaa aacaagcctt gctcacctac tatgtcagct ctgaatatat ttctctcctt
     4441 aagaaaaacc agattgtcag actagctcta gatagtcatg gaaatcaacc gatagtcatt
     4501 acgggaacaa ttaagaccat tgatgagcta gcgaccaaaa ccaagcaggg aaatcttttt
     4561 aaggttacag ccaaactaac actttctgaa aaagaaagca ctactattca atatggtcag
     4621 cagggacgag tgataagtgt tattgccaaa aaaacattct ttgactttta taaggacaag
     4681 ctctttaaag tgacagaata accatttagt gcttttcaac gaccatttag gacatatagt
     4741 acaacaaaga gtcaagataa gctataataa catagacagt atttaaaagg agcttttaat
     4801 atggataaac caactagaca atcaaaattt caggaactaa caccttctca attaactcag
     4861 attactggag gaggctggct tgaaggtctt caaaaagttt tcaatgtctc taagccaaaa
     4921 ctattagaat ggtaacattc tcccttttca aaacaccact atctaaagat actgagacac
     4981 tatccgaatg atttgatcct aaacatcaaa tctgagaggt gtaagacagt ttttctttac
     5041 tagtggtgtt tttttataac ctaagctcaa gtgtttgacc aaatacatga ttttgactta
     5101 tggtttttat catcacattg ggataacgat tgataatttc catagcattg taaagtccta
     5161 cacctctatt atcccccttg gtgcttactc cgaaatcata tagaaaggat agatcaatct
     5221 tctcttcctt agttgtattt tcaatcacaa atagttgctt attgtccaag gtaaaataag
     5281 aaatcgttat cttagacgaa gaagcttcaa cagcagcctc tatagcatta tcacataaaa
     5341 tagacacaat agtaagaaaa tcaatcagct ccatgccttg cggactaata gcctctggaa
     5401 cctctaagga tactgaaatc ccactttcta aagcctgact aaattttgca gctaaaagac
     5461 ttttcaaggc tgtgtcagtg acatggataa gacgcccaac atcatatttt ggcttgcgaa
     5521 accgtttatt tgaatcctta aagactgatt gataaactga cctaacaata gacatgtcat
     5581 tattatctat accaaacttt aacgtggcaa tcagattgct atagtcatga cgaaatcctc
     5641 gaacctctct gtaaagctcc tctatctgac gactatagct ctcaatattt gccagctgca
     5701 gctctctttg aaaggtcagc ctttcttgta gtgtatctct tagcgaccgg tccagtctcg
     5761 ccacagttcc cataaatata atccaatagc caagcatcat gcattgacga taggcataag
     5821 tatcaacagc tagctcatac tctaaataag caagtaattg gatcagaaaa taatagctaa
     5881 ccatagacca gttggtcaca cctaaaattc ttttatccct atcagataag agattaattc
     5941 tcaatgctct gaaatcatat cgtagccacc gcaaaaagag aaaaaccatc aaagtagata
     6001 ttatatctgt aaaaattccc cactcacttt gattaatgat atgacgattc aatcccagta
     6061 atggaacaac aaaaaaacca agcagtcggt accaaaggct ccacagggta ataggaaata
     6121 gtccataaaa tatcagtaac gtttttggca agggtcgcag caatagccat gatatcacta
     6181 ccatataaat gggaagactc caataattga gaagtgaaat gtcggcaaca tgattagcta
     6241 tagtgaaaaa aacagcaaat cctattctta aaaaagtact gaaagcaact tcaagccagg
     6301 ttaattgacg tccactgatt ttggaaaaga gcactaacga taagcctata cttgtcgtca
     6361 tttctaagaa aaataaaata agcttcatta attatctcct ctatgtaggt tctcaattgt
     6421 tgttaaaaca ctgttcattt tactacgagc aattaagcag ctagagccat ttcgaaaata
     6481 aaccactcgc tcaatcttat ctaccctaac gacattccta ggattaatca aaaaagaacg
     6541 atgacattgc aaaaaacgag actcttgctt caaaatatcc gtcaaagtcc ctgtaaattg
     6601 cattctctcc ttttttgtat acaaattgac acgatgcgct cgtgacgatg tctcaatata
     6661 caggatatca ttaaaaggca cctgtacctg agcataacga gatgtaaaat aaaaagcact
     6721 ttccgctatc gtttcactat tttgccgcac agcatataat aaagcagtct ctacccgttg
     6781 aacaaactca gtttgaggca gctctttatc gatatagtcc aaagcagata cctgatactg
     6841 aaaagccaag ggcataaatt ctgaatgagt tgtcacaaaa acaatcatcg catctggatt
     6901 tatctgacga atttgcctag caacctcaag cccttttttg tcctcatttt ttatctcaat
     6961 atctaaaaag aatagctgct gaccacagtt cttcttgata gcacttaata gctgatgagg
     7021 ccttccaaaa cagtcaagtc cttgaaataa tagctggtgc ttaacctcaa gctctttaat
     7081 gagcttttct aaatatctct gctgaatcat atcatcttct aaaataacta ctctcaccta
     7141 aactcagtcc cctatccaat ctgcagaagc attagcatta ctaccgtttc aacaaaataa
     7201 taagcacaat agcaaaaata aatccattaa aaataactgc atcaaatctc ataaaaataa
     7261 tattttgtac ttattttagc ataaaatacc atttttgaat acactaatct ctaataaact
     7321 aatgctatct agtcttagct ggcaataacc tagtgcttct aacaacaata atcagctcaa
     7381 caatttttag cagctacctt tttaaaaaaa agagactggg ataaaaagat ttctcaggta
     7441 agaaaaatag agattcacca aacagtgaat ctctattttt tgaactgaaa ctccttttgt
     7501 cccaaactca taagatgtat tgactttgtg agatgaacaa tttattacac ttgatttgat
     7561 catcggggtt tagaaaaaat agtgaaaaga atcctcataa ttcgtgaaaa atataatttc
     7621 tcacccaaaa atccaattca agattgtatt tataagaagt agcatgatta aagttataga
     7681 aattcttatc aacgcttctt cttttttaac aacaccaaat atcaatagta taatcggaac
     7741 taaaactaat actactaata atattgtttt ataatccatt gataatggcc tgtcctgcac
     7801 caacagtgca tcctattcct gcacccaata catacaatgg accagagaaa gcacctgtaa
     7861 cgattgctcc acctgcacaa tgccctgcaa cagagcccca attaatttta ccgccattta
     7921 cacttgccaa gtcaagctca tataacatct gaaaatcttc gtactgcttc atggtatata
     7981 ctccttcctt agttaaatct attacctatc attccaccca tacatgcaaa acctccccca
     8041 attgcaccaa catgtgcacc aacaaatgca cctggaagcg cgccaatccc tcctgctggt
     8101 gctccccaca aagccccact tccagctcct attaacatat atcctcccat gtctttaaga
     8161 cagtccttac cagagtatcc accttcaaca gttgcaagag cctttatatt cataacatca
     8221 aattgattaa tcgtttctgt at
//
LOCUS       DARYSY010000071         7621 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYSY010000071 DARYSY010000000
VERSION     DARYSY010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7621
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(153..434)
                     /locus_tag="TVR04_001746"
     CDS             complement(153..434)
                     /locus_tag="TVR04_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1270417.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQSKKSKID"
     gene            complement(467..1234)
                     /locus_tag="TVR04_001747"
     CDS             complement(467..1234)
                     /locus_tag="TVR04_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1270418.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFASTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLNNLLQHVPRSGVDIILCNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQVAR
                     HALKSNGRLAMVHRPDRFLEILDTLKTNGLAPKRLQFVYPKLGKEANMILIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKS"
     gene            1353..2093
                     /locus_tag="TVR04_001748"
     CDS             1353..2093
                     /locus_tag="TVR04_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1270419.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDRQKPGPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVNIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEGIEEVARRIQAEFDRLDQEMAPFKSSQRRSMLTYLYRIPLG
                     ILLVFILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3088
                     /locus_tag="TVR04_001749"
     CDS             2411..3088
                     /locus_tag="TVR04_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEL1270420.1"
                     /translation="MLEELFLKGKEMIKAPYFLSRCVTVVLSVGLLLVLWLALTGKEK
                     AREESAPFPEHSQVQQSEKPAQLEASEQEIAAEDIVVDIKGAVHKEGVYKLAKGSRIT
                     DLIELAGGLTDQADKNAINLAEKLSDEKVIYVAKLGENISVIKGSSAEAQSASADHQK
                     SEKVHLNRASLADLQSIPGIGAKRAQDIIDVRESLGGFKSLEDLRKVSGIGAKTLEKL
                     KHEISLD"
     gene            3069..5312
                     /locus_tag="TVR04_001750"
     CDS             3069..5312
                     /locus_tag="TVR04_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1270421.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVVLIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQLLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKIISPRSINDHISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHLPIDKIKLLEVV
                     CSFCYSGLTGHSISVVRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFILATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLCLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPLINEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWQRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDIDHVGD
                     LEAVAEAFSIKQIYVSRGSLTNTRFVKRLQRLAIKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5425..6486
                     /locus_tag="TVR04_001751"
     CDS             5425..6486
                     /locus_tag="TVR04_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1270422.1"
                     /translation="MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDFRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6564..7169
                     /locus_tag="TVR04_001752"
     CDS             6564..7169
                     /locus_tag="TVR04_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1270423.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
BASE COUNT         2071 a         1410 c         1766 g         2374 t
ORIGIN      
        1 tactagctag aagtcatgga ggttttgctg cttttttggt tttggacttt agtagcctcg
       61 ggctaaatga gccttgatct agtagcatgg gcttatctca gctgttgaca gtaagtccta
      121 tagaggtttg ccagcttagg tgtgtcagga gcttagtcta tcttagattt tttgctttgc
      181 tgctctgcaa tataggtgag cttttgctgt ctggtgtttc gttttttaaa caaggcttcg
      241 gctctcattg cagcctgctt gctatcaaag ctttcataat acagcaggct gacaggtaag
      301 cgacagcgtg tgtattttgc tcccttacca gcattatggg ctttgagacg cttgtctaaa
      361 tctgttgtat agccagtata gagggttttg tctgcacatt ctaaaacgta catataagcc
      421 ttttgagttg tcatgatgaa aaaacctctt gatgcaaaag agcctgctag ctcttaaaag
      481 ccttgtcctt ggctccgaaa taaatctcct taattgtatc ggtatagtct ccgttgtctt
      541 tatggacaat aagtggtggc aggattttca agccttccat agaaccatcc ttgatggcct
      601 caatcaagat catgttggct tccttaccaa gctttggata gacaaattgc agccgctttg
      661 gagcaagacc gtttgttttt aaggtatcta gaatctctaa aaagcgatca ggcctatgga
      721 ccatagctag acggccattg gatttgagtg catggcgtgc tacctgacag atcttagcta
      781 gatttgttgt gatttcgtgt ctggctagta gataatgctc agataggttt ttctttgagg
      841 tttgactgct tttaaagtaa ggaggattac aaagaatgat atcaacccct gagcgaggca
      901 catgctgaag taggttgttc aaatcatcac aaatcatcgt cacctgatcc tctagctgat
      961 tgagcctgat agagcgctgt cccatatcag ctaatcgtgg ctgaagctca atttcaacaa
     1021 tagaggcctt ggtttgtgta ctagcaaata agccgactgc accatttcca gagcacaaat
     1081 ctacaattag cccacgtgag ggaagctttg gaaagcgaga aagcaagacg ctatcaatag
     1141 aatagctaaa gacctctttg ttttgaataa tttgaacgtc gcttgagaaa agctggtcaa
     1201 tccgttcacc atcttttaat atcgaatgta gcatatcatt attatagcaa aaataatcct
     1261 atcagagtag ggggggctga ttgagctttc cctttaatat taaaatattt catggtacaa
     1321 tgagtaggat tataagtgaa aaggagactg atgtgtttta cgtctattta cgtggcttag
     1381 ttgtcttttt attgtgggtt gttaatggca atgcccacta ccataatgag gataggattc
     1441 ttgataagtc tgaaaattat attctagttg ctccacatag gaccttttgg gatcctgttt
     1501 acatggcatt tgctgcacgt ccaaagcaat ttatttttat ggcaaaaaaa gagctcttca
     1561 ccaatcgttt atttgcctgg tggattaaga tgtgtggtgc ctttccaata gaccgccaaa
     1621 agcctggtcc agatgccatt cggtatcctg ttaatatgct gaaaaaaagt aatcgctctt
     1681 tggtgatgtt tccgagtggg agtcgtcatg cgacagatgt caagggtggt gttgctgtta
     1741 ttgccaagat ggccaaggtt aacataatgc ccgcagccta ccaaggtccc atgaccctaa
     1801 aaggcttgct agcaggtgag cgcgttgata tgaactttgg tcatgcaatt gatgtttctg
     1861 acattaagcg tatgaatgat gaggggattg aggaggtagc taggcgtatt caggctgaat
     1921 ttgaccgctt agaccaagaa atggctccct ttaagtctag tcaaaggcgt tctatgctga
     1981 cctatcttta ccgtattcca ctaggaatac ttctggtgtt tattttggcc ttaaccatgc
     2041 tattttctta tttggcaagc tttgtttggg atccagacaa gcatcgctct taggtcgtgt
     2101 tatggattag cgctgaaggc gcgcaaaaat cagggctttg ttgctactct gctgaagctg
     2161 gcttgcagct acccttctga catgttatgt ctaggatacg aatgccactg gttagtcaaa
     2221 gctacaagaa agccagcact ttccacagta aggggattag gtaaggcaag gtaggttatg
     2281 cttgtagtgt agctgtatgt tacaatttga tgaggttgaa gaggtagtcc attttggact
     2341 gcttttttaa tatgctagaa aatagaacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaaa atgttagaag aattgttcct aaagggtaaa gagatgataa aggcccctta
     2461 ttttctgtca cgctgtgtta ctgttgtgct gtctgtaggg cttttgctgg tgctgtggct
     2521 tgccttgact ggcaaggaaa aagcaagaga agagtcagct ccatttcctg agcattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tagcagctga
     2641 ggatatcgta gtggatatta agggagctgt tcataaggag ggcgtctata agcttgctaa
     2701 gggaagtcgt atcacagatc tgattgagct agcaggtggc ttgacagacc aagctgataa
     2761 aaatgctatt aatctagctg aaaagctatc tgacgaaaag gtcatttatg ttgctaagct
     2821 gggtgagaat atatcagtca ttaaaggatc ttcagctgag gctcaatcag cgtctgctga
     2881 tcatcagaag tctgaaaagg ttcatttgaa cagggctagt cttgctgatt tgcaaagcat
     2941 tccaggcatt ggtgcaaaga gagcacagga tattattgat gtacgagaaa gcctgggtgg
     3001 ctttaaatct ctagaagatc tgagaaaggt atcaggtatt ggtgctaaaa cactggagaa
     3061 gctaaagcat gagatttccc ttgactaagt attttccaat tgctccgata caatttgccc
     3121 ttttagtgct tgttttgcat tatttgattt atcgacctag ctggttaacg gctggtttgt
     3181 tagctggctt gttggtatta ttaggctatc gctttgtcct caagcaggtc ttaaagacgc
     3241 ttcttttgct agggcttttt ggctgtcttt ttgcttatca aaagggtcag ctagaggcta
     3301 atcagatcaa tcagcctgat cgcttatcaa cggttgtgct gattccagat tcgataatgg
     3361 tgaatggtga tcacctatcc tttatcggtc ggcactcggg gcatcattat cagttggctt
     3421 atcgcatgac ctcaaaagaa gaggcagatt tttttaagca gcagagccaa ttgctaaagc
     3481 taaaggctga catcaggcta gaggaagcag cagggcttag aaattttaag ggctttaacc
     3541 atcaggctta tttagcttat cagggaatct ttagagtagg aaaaatcaaa agcttgcagt
     3601 cattgaagat tatctctcct aggtctatta atgatcatat tagccaatgg cgacgtcagg
     3661 ccatcgtttg gtgccaatct aggtttccac agccgatgag tcattatatg acaggattgt
     3721 tatttggcta tcttgataag tcctttgggc aaatgacaga gctatacagc cagctcggta
     3781 ttatccatct gtttgcttta tctggtatgc aggtcggctt ttttctgacc tacctgcgtc
     3841 gtggcttggt ctggttacat cttccaatag acaagattaa gctactggag gtggtatgtt
     3901 cattttgcta ttctggtttg actggtcata gtatttctgt ggtacgtagc ttgctacagg
     3961 cccagctgcg tcatattggt ctgacaggac tagataatct agcaatgact tttttgatga
     4021 tgtttttgat taatggtcac tttctgatgt ctattggtgg cgtcttgtcc tttgcttatg
     4081 cttttatcct tgctacggtc agatttgaag agctttctgg taataaacag aggcttttga
     4141 aagccttagc catttccttt ggcattgtgc ccttgctggc ctactatttc tcggttttta
     4201 atccgatctc ggtagtattg acagccttat tagcctattt gtttgatggt cttattctac
     4261 caggtctagc gatcttgttt ttcttctcgc cccttgctgt tgtgactgcc gtcaatccat
     4321 tcttcttatg cttagaaaag gggatcggca tgattggaag ctattttagt gctcccttgg
     4381 tgttaggaag tcctacagcc ttacagcttt gcctttgtat ggcttgcttg gctatagtgt
     4441 atgattatcg agggaatcga ggcttacagt tggttgcagg tggtttgttg ttgctgacgc
     4501 tctttacggt aaaatggccc ctgatcaatg aggtaacgct tgtagatgtt gggcagggag
     4561 acagtatttt tattagggat aagcaaaatc ataccatgct gattgatgtg ggaggagtgc
     4621 ctgctcctca ggaaaaggag caatggcaaa ggaaatacca ggcctgtaat gcccataaaa
     4681 cactcattcc ctatcttaga agccgagggg tggatacgat tgatcaactg gtgctaaccc
     4741 ataccgatat tgatcatgtt ggagatctgg aggctgttgc tgaggctttt agtatcaagc
     4801 aaatctatgt tagtcgggga agtttgacga atactcgctt tgtcaaacgc ttgcaaagac
     4861 tcgcaatcaa ggttaaggcc attagtgctg gtgatcactt gcccattatg ggaagctttt
     4921 tagaggtact ctatccttgg gagataggag atggtaaaaa caatgattct ttagtccttt
     4981 atggcaggct attggataaa agctttttat ttacaggtga tttggaggca gaaggagaag
     5041 aaaggctgat tgctcgttat cctaagctta aggctgatgt tttaaaggca gctcatcatg
     5101 gttctaaggg ctcttctata ccagcatttt tagaccatat ccagcctcag ctgagcttga
     5161 tttcagcagg aaggaacaac cagtatcagc accctaaccc cgaaacctta gcacgctttg
     5221 aagcgagaca cattccttac tacagcaccg caagcaaggg cgctattcgc ttaacaggtc
     5281 aagctcactg gcaattagaa tcctgtagat aggctcatcg agccagagct atatgcaagg
     5341 gcctaggtct ggcaatgaag tagagaatga aaaagatcag ctttagcaag gtcatattta
     5401 gtaagaaaat gctataataa aaccatgatt gcgatagaaa aaatagatgc cttaagcaaa
     5461 gaaagcttag gcttgattac ggtcgtagct ggtgaggata ttgggcaata tagccatatg
     5521 aaggcgctgc tactaaaaaa aatagccttt gatccggctg acttgactta ttcttatttt
     5581 gatatgtctg aggctttgta tcaaacagct gagatggacc ttgtaagcat gccctttttt
     5641 gctgaccaaa aggtggttat ttttgatcat ctgctggaca ttaccactag taaaaaaagc
     5701 tacctaaagg aaaaagagct aaaggcattt gaggactatt tggaaaatcc tgtagagacc
     5761 acacgtttgg ttatctttgc accaggaaag cttgatggca agcgtcgttt ggtcaagatt
     5821 ctcaagcgtg atgcccttat ttttgaagcc agtcctttga aggctgctga aaaaaggacc
     5881 tattttcaaa aatacagtca ccagctggac ttgagctttg ctagtggtgc ttttgatcaa
     5941 ttgctgctga agtcaaatga tgattttagt caaatcatga agaatatgac cttcttgaag
     6001 gcctataaaa aaagtggtcc tatcacagta gaggacattg ctcaagcgat tcccaagagc
     6061 ttgcaggata atgtctttga cttgacaaga ttggtgttac aaggaaagat tgatgctgct
     6121 cgggagctgg ttcatgattt gcgcctatct ggcgaggacg atattaagct tattgccatt
     6181 atgctggggc agtttcgtct gtttttgcag ctggcaacct tggtgcggtc tggaaaaaca
     6241 gaacagcagc tagtcactag cctatcagac ctgttaggca gacgtgttaa tccctatcag
     6301 gtgaaatatg cactcaagga ttttagagcc ttgtctctct cttatttgca gctggctgta
     6361 aagaccttaa ttgaaacaga ttatcacatt aaaacaggtg tttacacaaa ggattatctt
     6421 tttgaccttg ctctcttaaa gctagtagcg cattctcagg gaaatactga cctctcagac
     6481 ctatgagcat caatcaaatt agttgaaagc ctctattttt tgagataaga tagacttatc
     6541 ataaaggaaa agaggaaaga gacatgacca ttacattacc ggatcttccg tacgcatatg
     6601 atgcccttga gccttatttt gacacagaaa caatgacgct tcatcatgat aagcaccatg
     6661 ccacctatgt ggctaatacc aacactgctt tggaaaaata cccagagcta ggagaaaatt
     6721 tagaggaatt attagcagat gtaagcagca ttcctgctga cattcgtcag gctgtgatta
     6781 ataatggcgg tggccatttg aaccatgcgc ttttctggga gctgctttct ccagaaaagc
     6841 aagaggtttc tgctgatgtc gcagcagcta ttgatgacgc ttttggttcc tttgctgcct
     6901 ttaaagagca attcacagca gcagctacgg gtcgttttgg ctcaggttgg gcctggctgg
     6961 ttgtgaataa ggctggtcag cttgaaatca catcaactgc taatcaggac acaccaatct
     7021 cagagggcaa gcagcctatt ttagcacttg atgtttggga gcatgcttat tacctcaatt
     7081 accgcaatgt tcgtccaaat tatatcaagg ccttctttga aatcattaat tggaaaaagg
     7141 tctcagagct ttaccaagct gcaaaataat agaagtcagt taccaatctc agaagtagat
     7201 tggtttttta agtgccttat agtttggtca tgtcataaag ggagatctag tctataattg
     7261 acgccatcaa tccggtagta ttagcagatc agcaatgacg gctatttttg tgcaaaaagg
     7321 ctataggttc catttgtaat tagctgagtg atcttaaggc tatgcggtca taatagctat
     7381 caacttactg ctggagtgat ataaaaatgg ttaattggta agcaatgagt agtaactagt
     7441 tatcaattga tcgtatttct aattatttta cactaggtat taattgttgt attgagtgtt
     7501 atacttttta tgaactactt ttcctgtgat tttagtgttt tagattgact tttagatcct
     7561 catttgatat catttatatt agttaaagat gaaaattcaa ttaaaagaaa gtataggtga
     7621 t
//
LOCUS       DARYSY010000072         7438 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYSY010000072 DARYSY010000000
VERSION     DARYSY010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7438
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            229..1584
                     /locus_tag="TVR04_001753"
     CDS             229..1584
                     /locus_tag="TVR04_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270424.1"
                     /translation="MARHLETNAKRLQAAQERDQARFEAVAAADRASQGWVDLALSLV
                     TIAVGVAAIVMTAGAATPLVVGACVVGSGTVAYGASNLFEAGHNIYLGSVGDGLTVAS
                     NPLRDTLFMGNDRLYHQVGGLFTTASAALIPIGQTKSVAKGLTEFTIGEVGGFIGGQA
                     SYHGTKLLGCSEQDAQRATLVGNILGGFAASSAARRFSLNEPIAARVTKSAYNRQQLL
                     KNLENSKLARESSRFKGYVAREKFTTTLAVMSPEDSQRYIQWHKYAKAGLSPSDRVRI
                     LEISEKAPKIEYRPGKNSKTILAQAKGKRDSVELYLASEYIETHRHLFDDGATRFQKF
                     KPNVDYQDGLVGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYR
                     LDVSPEVVSQKGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAV
                     N"
     gene            1566..1988
                     /locus_tag="TVR04_001754"
     CDS             1566..1988
                     /locus_tag="TVR04_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270425.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKELEKNAIRKSPTVLIDIP
                     RFREYFTQEELKELIPIAEQQWIDWRGKLPDDYVSPLK"
     gene            2179..3333
                     /locus_tag="TVR04_001755"
     CDS             2179..3333
                     /locus_tag="TVR04_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270426.1"
                     /translation="MDLALSLVTIAVGVAAIVMTAGAATPLVVGACVVGSCTAAYGAS
                     NLYEAGHNIYLSHKGDGVTVASNPLRDTLFMGNDRLYHQVGGLFTTASAALIPIGQTK
                     SVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSEQDAQRATLVGNILGGLAASSAARR
                     FSLNELPTSKSFIDGMSPEDSQRYIQWNKYAKAGLSPSDRVRVLEISEKAPKIKLKSR
                     KNRQKFFKKIEAIDKEVTRRPDPSSYLAPEYIEAHRHLFDNGAARFQRFQPSESWNNG
                     VVGGKDGMSFWVSKDHADIIEDIAKGDNRLYETLLGFDEGYLGNDPLYRLDLSPKMVS
                     KKGVSIPSGNESGANEWWRPGGRTYPGNMPECVIKGISTKKGEHTWNVVN"
     gene            3315..3704
                     /locus_tag="TVR04_001756"
     CDS             3315..3704
                     /locus_tag="TVR04_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270427.1"
                     /translation="MERSQLTWEEVSQYEEVKGYGQQVWKHQGEYYLVREEGGIATQR
                     VVYKLPNELFQLLDSGRKSLLEIDFYVKNNCWPPNISQEEADRLFLRDNPELLENDVD
                     NQKLFTRKELEELLPKGSPILASSDSD"
     gene            3714..4136
                     /locus_tag="TVR04_001757"
     CDS             3714..4136
                     /locus_tag="TVR04_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270428.1"
                     /translation="MGITQMTWEEYETFNKVETPDNLYIREHNGTYYTVFELGIASVR
                     RIFELSAADFEEYLKGFRAADELLFKAQNDRWPPTEEEKRNVQKQLLIKHPISLIDVP
                     KSRAYFTQEELKELIPIAEQQWIDWRGKLPDDYISPLK"
     gene            4314..5321
                     /locus_tag="TVR04_001758"
     CDS             4314..5321
                     /locus_tag="TVR04_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270429.1"
                     /translation="MDLALSLVTIAVGVAAIVMTAGAATPLVVGACVVGSCTVAYGVS
                     NLYEAGHNIYLGSVGDGVTVASNPLRDTLFMGNDKLYHQVGGLFTTASAALIPIGQTK
                     SVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSDQDAQRATLVGNILGGYAASSAARR
                     FSLNEPIAAKVTKSAKITLSEKVLDTKVRFDESRIVAYAESMSKNYTEADVAKLTELT
                     THNAKTKTALLGYYEANSVTSYEQIAHQNKLTYFDAGSDGWNAMSRVDSKLAQRVNRE
                     FLIKQIEKRKTFILTSNPYTAQSIADVSGIGKSYAKEIQILAENGYNIEKFERFWRAY
                     K"
     gene            5318..5746
                     /locus_tag="TVR04_001759"
     CDS             5318..5746
                     /locus_tag="TVR04_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270430.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            5739..6143
                     /locus_tag="TVR04_001760"
     CDS             5739..6143
                     /locus_tag="TVR04_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270431.1"
                     /translation="MSEQYLPIKESLGYKNVKQALWTIFSVNLYEIPIHEGEDENFNF
                     VFTYKNCEMTMGISSTGKYTQFEAGEGGLFNVWFSHYVGKRFAITFLYEVIGDEGIKR
                     VFGKDEQSIEYAMRVLKDYLDSDEAKVLLKNE"
     gene            6187..6609
                     /locus_tag="TVR04_001761"
     CDS             6187..6609
                     /locus_tag="TVR04_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270432.1"
                     /translation="MARSQLEWEDVSQYEEVKGYVQQVWKHQGEYYLVREEGGIAVQR
                     VVYKLPNELFQLLDSGRKSLLEIDFYVKNGCWPPTEEETRNVQKELLIKHPISLIDVP
                     KSREYFTQEELKELIPIAEQQWIDWKGKLPDDYISPLK"
     gene            6841..7257
                     /locus_tag="TVR04_001762"
     CDS             6841..7257
                     /locus_tag="TVR04_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270433.1"
                     /translation="MSEEQYLPVKESLGYRNVKKALWSIFLIDLDDIQVREGEYENFG
                     FTLHYKDYSITMILSGTGKHTQFEFGEGGKLSILLPNPKDTLWGSSNLYELISDKVTK
                     EKLEYIFGKNEKDVEYAMHVLKDYLDSDEAKVFPNK"
BASE COUNT         2351 a         1248 c         1901 g         1938 t
ORIGIN      
        1 gtggattata gcgagctgat cactgatatc aatcgtttgg acgaggccat cattcaatac
       61 gaaagcaatc atgccagtca ggacttatcc gccttcaagg agcttttggc ttcaaccaag
      121 gccttgatag cagaatacag cagtaagccc aagcgggctg ggagctatca ggttggggat
      181 ataggacagc tcaataccat caaacgcttt gcgacagctt atcagggggt ggctcgtcac
      241 cttgagacca atgccaagcg tctccaagca gcgcaggagc gagatcaggc tcgctttgag
      301 gcagtagccg cagcggacag ggccagtcag ggctgggtgg atctggcact gagccttgtg
      361 acaatagcgg ttggggtagc ggctatcgtt atgacagcag gagcagcgac tcccttggtt
      421 gttggggcct gtgtggtcgg cagcggcaca gttgcttatg gggcgtcgaa tctttttgag
      481 gctgggcaca acatttatct aggtagcgtt ggtgatggac tcacagtggc tagtaatcct
      541 cttcgggata ccttgttcat ggggaatgac aggctgtacc accaggttgg tggcttgttt
      601 acaacagcca gcgcagcatt aatcccgatc ggacagacca agagtgttgc caagggctta
      661 acagagttca cgatcgggga ggtcggcggc tttatcggtg gtcaggccag ctatcatggc
      721 accaagctcc taggctgcag cgagcaagac gctcaaagag ctacattagt tgggaatatc
      781 ctaggaggat tcgctgcctc aagcgccgct agaagattca gcttgaatga gccgatagca
      841 gctagagtga cgaaatcagc ctacaaccgc cagcagctct tgaagaacct tgagaacagc
      901 aagttggcaa gggaaagctc aaggtttaag ggctatgtag caagggaaaa attcacgaca
      961 actcttgcgg tcatgagtcc tgaggatagc caacgctata ttcaatggca caaatacgca
     1021 aaggctggac ttagtccgtc agatcgagta agaattttag aaatatctga gaaggcaccg
     1081 aagatagagt atcgtccagg taagaattct aaaactattc tagcacaggc aaaaggaaaa
     1141 cgagatagtg ttgaactgta cctcgcttca gaatatattg aaacccatcg tcatttgttt
     1201 gatgatggag caaccagatt tcagaaattt aagcccaatg tagattacca agacggttta
     1261 gttggtgacg atttaggcaa tagtttttgg ttaagtacca aggacgcaga tattatccag
     1321 gagataggaa agggaaataa ccgtctttat gagacactct taggctttga tgaagggtat
     1381 ttagaagatg gtcccctcta tcgcttagat gtttcaccag aagttgtttc acaaaaaggt
     1441 gtttcaatac caagtggtaa tgaaaaaggg gcaaatagct ggtggcgtcc tggaggtcgt
     1501 acttatccgg gtaatatacc agagggagtt atgcaaggta ttagtacaaa gaaaggagat
     1561 cacacatggc acgcagtcaa ttagagtggg aagatgttag tcaatatgag gaggtaaagg
     1621 gctatggtca aagggtgtgg aagcatcaag gaaaatatta ctttgttgcc gaagaaggtg
     1681 gcattgctgt tcaacgagta gtatatgagt taccgtatga cttatttgaa ttgttggaaa
     1741 gtggagaacg tagtcttgga gatgttcatt caaagctaca agatggtaat tggccaccaa
     1801 cagaagagga gaagaaggaa ttagaaaaga atgctataag aaagagtcca actgttttaa
     1861 ttgatattcc tcgttttcga gaatatttta ctcaagagga attgaaagag ctaattccaa
     1921 tcgctgaaca acagtggata gattggagag gaaaactgcc agatgattat gtcagtcctt
     1981 tgaagtaatg tttaagatag cggagcagtg attagctctg ctattttaaa gcatgttctt
     2041 aataattagc ctgcgaccgc ttatcaggga gtagttcgtc accttgagat caatgccaag
     2101 cgtctccaag cagcgcagga gcgggatcag gctcgctttg aggcagtagc cgcagcggac
     2161 agggccagtc agggctgggt ggacctagcg ctcagccttg tgacaatagc ggttggggta
     2221 gcggctatcg ttatgacagc aggggcagcg actcccctag tggttggagc ctgtgtggtc
     2281 ggcagctgca cagctgctta tggcgcgtcg aatctgtatg aggctggcca caacatttat
     2341 ctaagccaca agggcgatgg ggtcacagtg gctagcaatc ctcttcggga taccttgttc
     2401 atggggaatg acaggctgta tcaccaggtt ggtggcttgt ttacaacagc cagcgcagca
     2461 ttaatcccga tcggacagac caagagtgtt gccaagggct taacggagtt tacgatcggt
     2521 gaggttggtg gctttatcgg tggtcaggcc agctatcatg gcaccaagct cctaggcggc
     2581 agcgagcaag atgcccaaag agctacattg gtagggaata tcctaggagg acttgccgcc
     2641 tcaagcgccg ccagaaggtt cagcttgaat gagctaccaa cttccaaatc gtttatagat
     2701 ggcatgagtc ctgaggatag tcagcgctac attcaatgga acaaatacgc aaaggcaggg
     2761 cttagtccgt cggatcgggt tcgcgttctg gaaatttcgg agaaggcgcc gaaaattaaa
     2821 ctaaaaagta ggaagaatcg gcaaaagttt tttaaaaaaa ttgaagcaat tgacaaagaa
     2881 gttactcgcc gaccagatcc atcaagttat ttagctccag aatacataga agcccatcgt
     2941 catttgtttg ataatggagc tgctagattc caaagattcc aacctagtga aagttggaac
     3001 aatggggttg ttggtggtaa ggatggcatg agcttctggg ttagtaagga tcatgcggat
     3061 attattgagg atattgccaa gggtgataat cgtctctacg agacgctact cggcttcgac
     3121 gagggttatc ttggcaatga tccgctctat cgcttggatc tttcgcccaa gatggtttca
     3181 aaaaagggtg tttcaatacc aagtggtaat gaatcgggag ctaatgaatg gtggcgaccg
     3241 ggaggccgaa cctatccagg taatatgcca gaatgtgtta taaaaggtat cagtacaaag
     3301 aaaggagagc atacatggaa cgtagtcaat taacatggga agaagtcagt caatacgagg
     3361 aagtcaaggg ttatggtcaa caggtgtgga agcatcaggg agaatattat ctagtcaggg
     3421 aagaaggagg aattgccaca caacgagtag tgtataaact acctaatgaa ctttttcaat
     3481 tattggatag tggccgaaaa tctttattag aaatagattt ttatgtcaaa aataactgtt
     3541 ggccgccgaa tataagtcag gaagaagcag atagactctt tttaagagac aatcctgagc
     3601 tattagaaaa cgatgttgac aatcaaaagc tctttacgcg aaaagaacta gaggagttat
     3661 tgccgaaggg atcccctatt ttagcaagca gcgatagcga ttaaggtaat aatatgggaa
     3721 taacgcaaat gacgtgggaa gaatacgaaa catttaacaa agtagagacg cctgataatc
     3781 tttatatccg agagcataac ggaacatatt atactgtttt tgaacttggt attgcttctg
     3841 ttcgccgaat ttttgagctt agtgcggctg attttgagga atatttaaaa ggtttccgcg
     3901 cagcagacga gcttctcttc aaggctcaaa acgatcgctg gccgccgaca gaagaagaga
     3961 aaaggaatgt tcagaaacaa ttgttgataa agcatccaat atctttaata gatgttccga
     4021 aaagtagagc atattttact caagaggaat tgaaagagct aattccaatc gcagaacaac
     4081 agtggataga ttggagagga aaactgccag atgattatat cagtcctttg aaataatgtt
     4141 taagatagca gagctgagat tagttctgct attttaatac tagctttgcg accgcttatc
     4201 agggagtagc tcgtcacctt gaggttaatg ccaagcgtct tcaagcagtg caggagcgag
     4261 atcaggctcg ctttgaggca gtagccgcag cggacagagc cagtcagggt tgggtggatc
     4321 tggcactgag ccttgtgaca atagcggttg gggtagcagc tatcgtcatg acagcaggag
     4381 cagcgactcc cttggtggtt ggggcctgtg tggtcggcag ctgtacagtt gcttatgggg
     4441 tgtcgaatct gtatgaggct gggcacaaca tttatctagg cagcgttggc gatggggtca
     4501 cagtggctag caacccgctt cgggatacct tgttcatggg gaatgacaag ctgtaccacc
     4561 aggttggcgg cttgtttaca acagccagtg cagcattaat cccgataggc cagaccaaga
     4621 gtgttgccaa gggcttaacg gagtttacga tcggtgaggt cggcggcttt atcggtggtc
     4681 aggccagcta tcatggcacc aagctcctag gtggcagcga ccaagacgcc caaagagcta
     4741 cgttagttgg taatatccta ggaggctatg ccgcctcaag cgccgccaga agattcagtc
     4801 tgaatgagcc aatagcagct aaagtgacga aatcagcgaa aataaccctt tctgaaaagg
     4861 tactagacac aaaggttcgg tttgatgagt ctcgcattgt ggcttacgca gaaagtatga
     4921 gtaagaacta tacagaagct gacgtggcca aattaaccga gctgaccacc cacaatgcaa
     4981 aaaccaaaac agctttgctg ggatattacg aagcaaacag cgttacttcg tatgaacaaa
     5041 ttgcacatca aaataagtta acttactttg atgctggaag tgatggttgg aatgcgatgt
     5101 cgagagtgga ttctaagcta gctcaaaggg ttaatcgtga atttttgata aaacaaattg
     5161 agaaaagaaa aacatttata ttaacgtcta atccatatac tgctcaatca atcgcagatg
     5221 ttagtggtat cgggaagtct tatgctaaag aaattcagat tttagcagaa aatggatata
     5281 atattgaaaa atttgaaagg ttttggaggg catataaatg agtgaagaac agtatttacc
     5341 agtaaaggaa agcttaggat atcgtaactt aaaaatagct ttaatgaatg ttttttcaat
     5401 agatttggat aagtttacaa ttattgaagg agaatttgaa aattttggtt ttcatttaaa
     5461 ttataacaat aaagaaatca taatctggat tacatcaact ggtaagaata gacaatttga
     5521 atatggagaa ggaggacaat tgatgatttc acttcctaat ccaaagtatc ctgatagatc
     5581 ctttcttgat agggtaacct tagaaagtct tttaacagac accgaaaaaa tagaagcagt
     5641 tgactatgct tttggaagat acgagcatcg tctcgaaata gcgttggcca ttctaaaaga
     5701 ttatttagat tcagacgaag caaaggtttt attgaaaaat gagtgaacaa tatttaccaa
     5761 taaaagaaag cttaggctat aagaatgtta agcaggcttt atggactatt ttttcagtca
     5821 atctttatga gattcctata catgaaggag aagatgagaa ttttaacttt gtctttacat
     5881 ataaaaattg tgaaatgacg atgggtattt cctcaacagg taaatataca cagtttgaag
     5941 ctggcgaagg tggattgttt aatgtttggt ttagtcatta tgttggtaag agatttgcaa
     6001 taacattttt gtatgaagta ataggagatg agggtataaa aagagttttt ggcaaggacg
     6061 aacaatctat tgagtatgct atgcgtgttt tgaaggatta tctagattca gacgaagcaa
     6121 aagtgttatt gaaaaatgag tgaacagtat ttagcgatta agctataaaa acggaggaga
     6181 tcacacatgg cacgcagtca attagagtgg gaagatgtta gtcaatatga ggaagtcaag
     6241 ggttatgtcc aacaggtgtg gaagcatcag ggagaatatt atctagttag ggaagaagga
     6301 ggaattgctg tacaacgagt agtgtataaa ctacctaatg agcttttcca attactggat
     6361 agtggccgaa aatctttatt agaaatagat ttttatgtca aaaatggttg ctggccgccg
     6421 acagaggagg agacaaggaa tgttcagaaa gaattgttga taaagcaccc aatatcttta
     6481 atagatgttc cgaaaagtag agaatatttt actcaagagg aattgaaaga gctaattcca
     6541 atcgctgaac aacagtggat agattggaag ggaaagctgc cagatgatta tatcagtcct
     6601 ttgaaataat gtttaagata gcggggctga gattagctct gctattttaa agcatgttct
     6661 taaaagttaa tagaattagc aacccataat aaggaaggga aagattttgt acttatttct
     6721 aattcgtata atgctaaacg gatagctgtt gagacgagta taggaaagtc atatgttatt
     6781 acttttacga gaaaaaggct ataaacttga ggaatttgga aattattgga gggcatataa
     6841 atgagtgaag aacagtattt accagtaaag gaaagtcttg ggtacaggaa tgtaaagaaa
     6901 gcattgtgga gcatattttt aattgattta gatgacattc aagttagaga aggagagtat
     6961 gaaaatttcg gatttacatt gcactataaa gattattcca taacgatgat tctgtctggg
     7021 actggaaagc atactcaatt tgaatttgga gaaggaggga agttaagtat tttactacca
     7081 aatccaaagg atactctgtg gggaagttca aatttatatg aattgatttc tgataaggtc
     7141 acaaaagaaa aactcgaata tatttttggt aaaaatgaaa aagatgttga atatgccatg
     7201 catgttttga aggattatct ggattcagac gaggcaaagg ttttccctaa caaataaacg
     7261 gttggaatag tttgatgatt tagctaatat tcagaagggt gagattgcca aagtatttgg
     7321 gcaaggtgga ggaattcaga ttaaatttcc gacaggtgtt ggtatttaca agaaaatggg
     7381 tttattaaag gagattaacg agatggataa tacaaatata ttgaattgga aaaaagat
//
LOCUS       DARYSY010000073         7067 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYSY010000073 DARYSY010000000
VERSION     DARYSY010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7067
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(153..596)
                     /locus_tag="TVR04_001763"
     CDS             complement(153..596)
                     /locus_tag="TVR04_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270434.1"
                     /translation="MMTVKINNRKLWLGLIIAVGAMIMLFSLNGKITEEQQKRDLETS
                     IAKLLVSDYEGVETIKFTGWGHSRETGSWGTTVVINGENEMGFSFDGLSGLADISGRS
                     YHPDTFKLVEKNSLEEMGPVKYRIKDIEKVSLERVAVTHSHEKRS"
     gene            complement(960..4511)
                     /gene="smc"
                     /locus_tag="TVR04_001764"
     CDS             complement(960..4511)
                     /gene="smc"
                     /locus_tag="TVR04_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1270435.1"
                     /translation="MFLKEIQMQGFKSFADRTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMLDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALAALREDLAAYHRKRQSLETENHHLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSHQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVKLLQQE
                     ADMSNQLTAVIAQLDKESQTRENQEQEYQALQAKVDQLNQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTMLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAVAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGANRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEEARLAEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTDQSSERLLSEKARLEEALELLADEKSTLTSEIEQIKENKDTIN
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELADLEAVLSHQVSQ
                     EAIDQLPHLENQLTEANQRKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLTFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFQETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(4512..5204)
                     /locus_tag="TVR04_001765"
     CDS             complement(4512..5204)
                     /locus_tag="TVR04_001765"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1270436.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GKGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDRLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(5463..7043)
                     /locus_tag="TVR04_001766"
     CDS             complement(5463..7043)
                     /locus_tag="TVR04_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270437.1"
                     /translation="MTFKSYQLKCIWSYKLIRREIILLDYYLERDIVERKLILAVLLT
                     EKEITLDSLCSQTSITPRKAKEYLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFH
                     SIYASSDTLKILKFLLTDNYRTKCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDID
                     DYRVIGDEYRIRYLIAMLHKEYGFAVYEMTPKDMEIIHAFIFSTPTRLKPSVFLDKKF
                     YLFDILLMLSWKRQNYDVSLPQLTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGD
                     LDYLYLVYLTVDSSFLMHYWNDKQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQ
                     MYFLLPFFRRCLFQLHDLISFQDYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSP
                     GHLHFMCLHLEQMLELSLPPVEVIIVENKRALGDVLSYFVISSIPSYKVNITRINMLT
                     DSLENYEQAPDFVITSDNILPFLEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFH
                     RKHYEQLLEQLLIGDRVE"
BASE COUNT         2019 a         1698 c         1240 g         2110 t
ORIGIN      
        1 tttttccata atgttatccg ttatgagtta aattctccag ctcataatct ttccattaaa
       61 acaataggga catcattaac ttagctttgc taggttagat attatagacc tgttctgaca
      121 acttcttata actactatcg gatatcgtca tattaactcc ttttctcatg agaatgcgta
      181 actgccactc tctctaaaga aactttttca atgtctttaa ttctatattt cacaggcccc
      241 atttcttcca gactattttt ctcaactaac ttaaacgtat ctgggtgata agagcgccca
      301 ctaatatccg ctaatcctga caagccatca aacgaaaagc ccatttcatt ttctccattt
      361 ataactactg tcgtccccca cgaacctgtt tcccgagaat gtccccagcc tgtaaactta
      421 atggtttcaa caccttcata gtcactgacc agcagcttag cgatactggt ttccaagtcc
      481 cttttttgtt gttcttctgt gattttgcca ttcaaactaa aaagcattat catcgctcct
      541 actgctatta ttaagcctag ccacagcttt cggttattaa tcttaactgt catcatgtcc
      601 tccccttcac ccttttgctg acaaccgtca ctctaagaaa gacagcatga ctaattaggg
      661 tgaaattaat ataaaatctt atttatatta ttctcatttt gtaattaaat tataatatac
      721 agacatctac ttgtcaatat attatgtcct tagttacttt tttggtatat tttaattaaa
      781 accagccgcg ccaagttcta ggagcatgtc aaaaacaaca gcttactgct agtcaatcct
      841 cgcactttgt tctttggaaa gccaaaaaac ctatcatgac gataggtttt ttatagctta
      901 ttcttagtta tcatctgcta catgtagaaa tacagctaaa actaagctct gtcctagagt
      961 tatgacaagt aagtcagatc ctgcgtatcc ttgagcttaa cagatactac cttagaaaca
     1021 ccagattctt gcatggtaat cccataaata ctgtctgctg ctgccattgt ccccttgcgg
     1081 tgggtaacca cgataaactg actatccttg tcaaaacgat tgagataatc tccaaaacgc
     1141 ttgacattgg cctcatcaag ggccgcctca acctcatcta aaatcacaaa gggaatggtc
     1201 ttaatgcgga taatagcaaa taaaagggct agcgctgata aggctttttc tccgccagac
     1261 atcacattca aagattgaag ctttttacca ggcggttgca ctgaaatatc tactccagca
     1321 gaaagcagat cagtctctgt caacatcaag tccgctgagc ctccaccaaa catctgccta
     1381 aaggtctcct gaaagctatc gcgaatagcc tcaaaggtaa ccctaaagcg tgccttgacc
     1441 tcatgatcca tattgccaat cgtatctacc aagagattct tggccttgat aaggtcagcc
     1501 ctttgaccat ttaagaaggt caaacgctca ctaacctcat caaattgagc aatagcatca
     1561 ctattgattg ggcctagggc acgaatgctt tgctgaacct gctgcaattt ctgtcttgct
     1621 gctgccatgt cagtgtcatt gattgggctt gcctgctcct tggcctcctc taagcttagc
     1681 tgaagctcct ctgataggct tctagcgtgc tgccgtaagc gaccaataac ctgctctaag
     1741 tcagcctcca gtcttgcctg ctgacgaatg aacgcttcat ttttcttagc ttccttaagt
     1801 agctgagcct ctagctcctc cagtctggcg tcatagtcct caccttcaaa gcgcagctga
     1861 atgaagcgct cctgagtctt gatcttgcgt tgattagcct ctgtcagctg attttctagg
     1921 tgaggcaatt ggtcaatggc ctcctgacta acctgatgtg ataaaacagc ctccaaatca
     1981 gctaattcct tctgaccttg agcgatcatc gtctccaagc gacgctggtt ggctgcttca
     2041 aactttttct cgttgagtaa atctcgctct ttaagacgag cctgagataa ttcttggcta
     2101 agctggtcct tcttttgatt aatcgtgtct ttgttttcct taatttgctc aatttctgac
     2161 gttaaggtcg atttttcatc agctaagagc tccaaagcct cctccagcct tgctttttct
     2221 gataataaac gctcactaga ctgatcggtc tgacgattgc tgagaagctc taacagctct
     2281 tttgagtcag ccagcttttc tgccagctgc tgataggcca attgtgtttt ttgctcggcc
     2341 agtcttgctt cctcaccagc cagcttagta tcagcctgtg cagccttttt agccttcaaa
     2401 tcagcctgta cagcagctac tgctttttca gattccttga tctgctcaga aagcaaggct
     2461 aattccttct caatctgctc tagctctggc ttgataaagg ttgtgctatt gtgacgatta
     2521 gccccccctg aaaaggcacc accgggacgc agctcggtac catcaagcgt tacaatcctg
     2581 accttataat gcagctgctt agctgcctga ttagcatgat caatggtatc aaaaatagcc
     2641 gtcacaccta acaggctttg tacaatagcg accaaagagg gctcataggt caccaaagaa
     2701 tcagctgtgc ctaaatagcc ctgacaagcc ctgagctgct tgagagtcac ctcagaaagc
     2761 tgacgggcct taatcgttgt cagaggtaaa aaggtcgcac gcccctgacg attagccttt
     2821 aaaaaggcta tcgctcgctt ggctactgcc tcatctgcca cgataatatg ctgactacta
     2881 gctcccaaag caatctcaag tgccgtttga tactgactat caaaggtcaa atgctcacta
     2941 acagctccta aaataccatc tagcttacca gcagcttgaa gcactgccct aacacctgcg
     3001 taaaattgac tatgattttt ttggatagaa accaaactag ccctacgagc ctccttggct
     3061 tttttctgat ctaacaaatc aaaaagcatc gtttgtccct gatgataatc ctgctctaag
     3121 gcttcaactg tctttgctag ctcttgataa tcagctagga gctgctcaag ccttgattga
     3181 ctagcttgat aagctaaaag ggcagtctgt gtgtcctgat tgagctggtc gaccttagcc
     3241 tgcagggctt gatattcctg ttcctgattt tctctggtct ggctttcctt atccagctga
     3301 gctattacag cagttagctg attggacata tcagcctcct gctgcagcaa tttaacaaaa
     3361 tcctcacgaa gagcctcaag cagctgatct ggatcgctag aaaatcgctc aagctcctga
     3421 gaaagctcgc tgaccttggt attaaactca gctaaggctt gatggatctc atctagctga
     3481 tgactctttt gctgatgttc ctgttgaaaa gcaagcaatt gctcctgagc ctgctgcctg
     3541 cgctgactgg cctctgtttt cttttcctgc ttttgactaa ggtccagctt gatgaggtca
     3601 atctgtcgct ccagatctga tatgaccttt gtcaattcca gcaaatcagc ctgcgtctgc
     3661 tcagctacag cagagagctt ttgccgcttg gtttttaagt gatgattttc cgtctctaga
     3721 ctctgacgct tcctatgata ggccgctaga tcctcacgaa gagctgctaa ggccttttct
     3781 tgagcctcct gctccatacg gtcttgctct atatccttga ccaaaatatc cagctgtagc
     3841 tgcttacgat cagcatctaa ggctaaaaat tgcctagcag ttttcgcctg tctttctaga
     3901 ggaccagctt gatgctcaag ctcatagata atatcgtcta agcggtcaag attatcttga
     3961 gtttggttta acttagtttg cgtctccttc ttgcgggtct tgtatttcaa aactccagct
     4021 gcctcttcaa agatggcccg tctttcctct ggcttgctat taaaaatctc ctcaacacga
     4081 ccttgagaaa taatggaaaa cgaatcacga cccagtcctg tatccatgaa cagctcatgg
     4141 atatctctta gcctaacctt tttgccatca atcagataat cgctgtcgcc attgcgatag
     4201 atatgcctct ccacacgaat ctctttctga gcattcttga taaaggcatc tgaattatcc
     4261 aagacaacag ccacctctgc ataattcaag ggactccgat gctcagttcc agcaaagatc
     4321 acatctagca tcttaccacc gcgcaggctt ttggcactgg cctcaccaag tgcccaacga
     4381 aggctttctg tcacattact ttttccagag ccatttggcc ctacaacagc tgtgaccccc
     4441 ttatcaaaga taatcttggt cctatctgca aaagacttaa agccctgcat ttgtatttct
     4501 tttaaaaaca tttagacctc actaagttgg gctagggcat ttttagcagc atcctgctct
     4561 gccagttttt tagatctacc tgtccccttg ctaagacgat cctcaccaac caatacagct
     4621 acctcaaatt gcttagcatg agctggtcca gtctcgctaa tcacctgata atcaatcaca
     4681 acatcaccct tagcctgtaa caactcctgc aagcaggttt tataatcctt gaccttctca
     4741 aaggttccct gctcaacctg tggaatcata acctgattta aaaagcggcg aacctcttca
     4801 atgcctttat ccaaaagaag agcacccaaa aaagcctcga acaaatcgcc taaaatcgta
     4861 tcacgatgac ggcctcctga tttttcctcg cccttgccaa gcttaatata agcatcaaac
     4921 gaacaatagc gtgaaaagcc tgctaagctt tcctctctga caatcgttga tctgagtttt
     4981 gacatatcac cctcagtctg cttaggatac ttggcaaaga ggtattctga aataattaac
     5041 tgtagaacgg cgtctcctaa aaattccaaa cgctcattat gtgaaatgtt taggaggcga
     5101 tgctcattag cataagaggt atgtgtaaag gcagtctcta gtaatctttt atcatcaaaa
     5161 cggatattaa aagagttttc cagcagggcc tcaagctttt tcatcatgac aaatctcctt
     5221 ttctaatgtc cttataaacc attctattat aacaaaaatc cacttgaaag gcttatcaca
     5281 agtggatttt tcagaaatta ttgtaccaaa tagacacgag ctattggctg ctgctattta
     5341 gcataggtgt tatcacgatc agcagtaagc caatcaaaac aggtatcgct aaagcaagtc
     5401 ctcacaaaaa atggtctaaa gaaaaaccta gtagctttat accacttgct tagcaaaaaa
     5461 ccttactcta ccctatctcc aatcaagagc tgctctaaaa gctgctcgta atgcttacga
     5521 tgaaagttga gaattgattt taccactgtt tttccctgct ccttaatgta atccatgctc
     5581 ataccaatta agacgctctt atctggaaat acctgctgct cctcaagaaa aggcaaaata
     5641 ttatcactcg taatcacaaa atcaggagcc tgctcataat tttccagact atctgttagc
     5701 atgttgatac gagtaatatt aaccttataa gaaggaatac ttgagataac aaagtaagac
     5761 aagacatcac ctagtgctct cttgttttca acgatgatga cctctacagg cggcaaggac
     5821 agctcaagca tctgctctaa atgaaggcac ataaaatgca ggtgccctgg tgagagcgtt
     5881 tctgactggt agctaaccat cagccagtcc ttgatttgct cctcaacctt ttctagcagc
     5941 agctgactgc cttgatacct ctttgaatag taatcctgaa agctaatcaa atcatgcaat
     6001 tgaaagagac atcttctgaa aaagggaagc aaaaaataca tctgatccct taaatgaagc
     6061 tgacgaccaa acaacatttc caagcgatta acaagctcct tatacagtgg atcttcttct
     6121 aagatattgt agacaagacg taattgcttg tcattccaat aatgcataag aaaagaacta
     6181 tcaactgtaa ggtaaaccaa gtaaagataa tctaagtcac cagaattaaa cacaacctga
     6241 gtacgtgtct caatttcttg cttagcatag caactgattt gctcaaaaat agataattct
     6301 tttaaacgat caaataaagt aagctgtggt aaggatacat cataattctg cctcttccaa
     6361 gacagcatga gtaaaatatc aaaaagataa aatttcttgt ccaagaaaac agagggcttt
     6421 aaccgcgtag gggttgaaaa aataaaggca tgaataattt ccatatcctt aggtgtcatc
     6481 tcataaacag caaacccata ctccttatga agcatggcaa ttaagtagcg aatccggtac
     6541 tcatccccta taacccggta atcatcaata tccaaatgaa tggattgcag gtagcccttt
     6601 agcttattga caagatgata ggcctttgat ttggaaataa actgtcttct gatgaaagtt
     6661 gtcagacact ttgtcctgta attatccgtc aacagaaact tcaaaatttt aagcgtatca
     6721 gatgatgcat aaatactgtg aaaatacttt tccttgttat taggatcaaa ctcacaggta
     6781 atgcctgact tcaatacagt aatagacagg tctttgtcaa atagagcatt aatctgatta
     6841 aggtattcct tagcttttct gggagttatt gacgtctgcg aacacaatga atcaagtgta
     6901 atctcttttt ctgtcaataa gacagccaat attagttttc gctcaacaat atctctttct
     6961 aaatagtaat ctaacaaaat aatctctctc cttattagtt tgtatgacca tatacatttt
     7021 agttgatagg atttaaaagt caactaaaaa aaatacacaa aaaataa
//
LOCUS       DARYSY010000074         6903 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYSY010000074 DARYSY010000000
VERSION     DARYSY010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6903
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(334..1677)
                     /gene="brnQ"
                     /locus_tag="TVR04_001767"
     CDS             complement(334..1677)
                     /gene="brnQ"
                     /locus_tag="TVR04_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1270438.1"
                     /translation="MVRKGFLTGLLLFGIFFGAGNLIFPPTLGVGSGQEFWSAILGFC
                     LSGVGLAVITLLLGTLTNGGYREEMTQKFGAWFSLAFLVVLYLTIGPLFAIPRTATVS
                     FEVGISPLIGYSPLALFLFSACFFAAAYFLAIRPNGILDSVGKILTPVFALLILLLVV
                     VGALVYGGHEPAQASAAYAGQAFGGGVLAGYNTLDALAAVAFCLVATETLKQFGFQSK
                     KEYLSTIWVVGIVTSLAFSILYIGLGFLGNRFPIPADVLADPNVNQGAYVLSQASYQL
                     FGSFGRLFLSVMVILTCFTTTVGLIVSVSEFFEKSFRFGNYRLFARLFTFVGFLIANL
                     GLNAVITFSVPVLTLLYPIVIVMVVIILLNKLVSLSKKGMTLTIGLVALVSLMEVLAS
                     QFQLGALTALVGLLPFHTVSMGWLVPGLVGLLVAMLLPDKQKGQAFDLEAFNHQD"
     gene            complement(2236..4410)
                     /gene="nrdE"
                     /locus_tag="TVR04_001768"
     CDS             complement(2236..4410)
                     /gene="nrdE"
                     /locus_tag="TVR04_001768"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1270439.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSRRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAAGFEQLIATSIRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRVYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVPFTDTNASGEACQSCML"
     gene            complement(4456..4866)
                     /gene="nrdI"
                     /locus_tag="TVR04_001769"
     CDS             complement(4456..4866)
                     /gene="nrdI"
                     /locus_tag="TVR04_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1270440.1"
                     /translation="MAARIMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNNANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVLKVQAILAGDWLSY"
     gene            complement(4868..5881)
                     /gene="nrdF"
                     /locus_tag="TVR04_001770"
     CDS             complement(4868..5881)
                     /gene="nrdF"
                     /locus_tag="TVR04_001770"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1270441.1"
                     /translation="MTQYYYDRSQSPIDYALSQSKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETTDDD
                     WEF"
     gene            complement(6338..6574)
                     /locus_tag="TVR04_001771"
     CDS             complement(6338..6574)
                     /locus_tag="TVR04_001771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270442.1"
                     /translation="MINDIRNVRREVKLTRKANKILEDMLRVAPSDSFSEFIRKRLLN
                     NFPEEKYIENFLENYLKIELLYGIRNISRDIHKI"
BASE COUNT         2138 a         1592 c         1362 g         1811 t
ORIGIN      
        1 gtctatttag aagctagtaa gggctgagaa accaaaaaca cagcccacaa ggcttggctg
       61 atactataga tacacaccaa tagtcttaga agcatcgtaa gaaaaaacac tttgcaaatc
      121 aagtaactct aggatcacgc tttttcacta tgctaagagt agctagacgc cttaagcagc
      181 actagggtat cttgcactag gtaggcatta gcaaaaagct agtgcaagtc acactactag
      241 acaaagaaaa aagaccccac tcaaggtcat tgagtgagga tctttaaggt aagaacactg
      301 cttaaatagc tcttgctata gcgatgatag gtactaatcc tgatgattaa aggcttctag
      361 atcaaaggct tgaccttttt gcttatccgg caaaagcata gccacaagca agcctactag
      421 acctgggact agccagccca tagacactgt atgaaagggc agcaagccta ccagtgctgt
      481 caaagctccc agctgaaatt ggcttgccaa gacctccatc aaggagacca aggccactaa
      541 gccaatagtt aatgtcatgc cctttttaga gagagatact agcttgttga gcaaaataat
      601 aacgaccatg acaataacaa tcggataaag cagggtcaag accggaacag aaaaggtaat
      661 gacagcattt aagccaagat tagcaatcaa aaagccaaca aaggtaaata atcttgcaaa
      721 gagcctgtaa ttcccgaaac gaaagctctt ttcaaagaac tctgaaaccg agacaatcag
      781 accaaccgtt gtggtaaagc aggttaaaat aaccatcaca ctaaggaaca agcggccaaa
      841 ggaaccaaac aattgataag aggcctgaga cagtacgtaa gcaccttggt tcacattagg
      901 atcagctaaa acatcagctg gaataggaaa cctgttgcct aaaaagccaa gaccaatata
      961 aagaatgcta aaagcaagac ttgtgacgat acctaccacc cagatagtcg ataggtattc
     1021 ctttttactt tgaaagccaa actgtttaag ggtttctgtt gccaccagac aaaaagcgac
     1081 agctgccaga gcatctaagg tattgtagcc agccagaaca ccgccgccaa aggcctgacc
     1141 agcataggct gcgctcgctt gagcaggctc atgccctccg taaacaagag ctcctaccac
     1201 cactagtaat aaaataagca aagcaaagac tggtgttaaa attttcccaa cgctatctag
     1261 gataccgttt ggcctaatgg caagaaaata ggcagccgca aaaaagcagg ctgaaaacaa
     1321 gaagagagca agtggactat aaccgataag cggactgatc ccaacctcaa aggaaaccgt
     1381 tgccgttctt ggaatggcaa aaagaggacc aatcgtcaaa taaagaacaa cgagaaaggc
     1441 tagcgaaaac catgccccaa atttttgagt catttcctct ctgtaaccac catttgtcag
     1501 tgtgcctagc aaaagcgtaa taaccgctaa tcctacacca gataggcaaa agcccaaaat
     1561 cgcagaccaa aattcctgac ctgagccaac acctaaggtc ggtggaaaaa tcaaatttcc
     1621 tgctccaaaa aagataccaa ataaaagtaa gcccgttaaa aatccttttc taaccatcgg
     1681 caaccactta tgtaagctgg aaagcctaca ccctttctgt acaaaatact agcactccag
     1741 tcaagctagg ataggcacag ctaaaccctt gtctctcaca ctatgctgtc taagcccgac
     1801 cagctatttt tttattataa cagaatattt tagaaatact ataggttatt ttgaattttc
     1861 tgactgtttt gacagttaca agaaaaccca gtggttaata tggaaacaaa cctcagtaat
     1921 caccgattca aaaggagcct ttttcttgat tcccctttag caaatcagca agcattgggc
     1981 ttatcaaaca aactgtcctt acaacaagca ccggtagccc acttcgtttg gcaaggcctc
     2041 tgttaaccat cagtggtcac gaccacaagc caggctgacc tgcattaagc tcaagagagc
     2101 ttgctatcag cctgttggac caaaagatac tctaagccta ttaacaagcc aactagacag
     2161 agcttgggtg agccaattcc ttcatgctgg atgaaggctt acttggtgct gcctattttt
     2221 aacgctaaaa aagatctaaa gcatgcagga ttggcatgcc tcgcctgaag cattggtatc
     2281 ggtaaacggt acaatcgtat cttcctcata ctgctcgctt ccttctagga cgtcctgtct
     2341 gacgcggaca taataaatgg acgcacactt tagcttaaag gcatgtatgt aggcacgatt
     2401 gagatcacgc gttgttgctt ggtctgtcat aaacagggtt aaggaaattg cctgatcaac
     2461 gtgcttttga gccgctgcta cgatattaat aataggctca ggcccgacct cataggcacc
     2521 acgctcgtaa taggcatagt tatcatcact tatctgataa gcaggcacat aaacccttcc
     2581 taagtgaccc tcctttcgca cctcaactgg tgcaacaaca ggctgtaagc tcggtgtaca
     2641 tgaggacaag tagctgatcg atccggttgg tgcgactgcc atcaagtgtg cattggcaag
     2701 gcctgtctct tgaatcgtgg caaccaattc ctgccaatca gccacactag gcactcgaag
     2761 cccgtagcgc tcaagcaagg ccgcaacctt agctgtctta ggcttagcct cttttgtcaa
     2821 atagcgggca aagtagctgc catctgcata ggttgactgc tcaaagccag caaatgctcc
     2881 cttttcctta gccaattgac tagaagcctt aaaggcataa taggccattg tgtgaaaaaa
     2941 gagatcagta aaatctactg cttcagctga atcataaaag atgtgattgg tcgccaaaaa
     3001 accatgcagg ttcatcgccc caagaccaac agcatgatta gcagcattcc ccttttcaac
     3061 agaaggagca cagctgacgt ctgaagctct tgacacatga tccaaggccc taatgctggt
     3121 tgcaatcaat tgctcaaagc cagccgcatg cttcatggct tcggcaatat taatggagcc
     3181 aaggttacag caaatgtcct cgccgatttg cttaaaggtc aaatcctctt caaaggtgct
     3241 ggctgtgctg acctgagcga tttcagagca aaggtttgac atgacaatcc gtcccttttg
     3301 agggtgtgga ttgcgcttat taaccgtatc atcaaacaag agataagggt agccagattc
     3361 aaaatgaagc tctgcaataa gctgaaagag cttacgggca ctgatatagg tctttttaat
     3421 ggctgggttg gccactaggc ggtcatactc ctcggtaatg gcaatatctg acatgtcctt
     3481 gccataaact cgcttaatgt catagggaga aaatagcgcc atgtccttat tttcccgtgc
     3541 cagctgaaag gtaatatcag gaataacgac acccagcgcc agtgacttga tacggatttt
     3601 ttcgtctgca ttttctctct tcgtatctaa aaaggtcaga atctctgggt gatgcacatt
     3661 gaggtaaacc gcacctgctc cctgtctttg ccctagctga ttggcatagg aaaaggaatc
     3721 ctccagtagc ttcatcactg gcacaatgcc tgtcgcttga ttttcaatgc cttttatggg
     3781 agagccaacc tctcttagat tggttaaaca caaagcaacg ccgccgcctc tttttgagag
     3841 ctgcaagctc gtgccaatcg cacgcgaaat agattccatg ttgtcttcga ttcgcagcaa
     3901 ataacaggaa atatattcgc ctcgacgctt tttacctgca tttaaaaagg taggggtcgc
     3961 cggttgaaag cgcctgctaa gtatctgatc aatcaaatcc cgcaccaaat caggatcacc
     4021 attagccaaa aacaaggcat tcatgacagc acgatcctca aaatgctcta ggtattgtga
     4081 cccatctaga gttttaagcg cataggactg gtaaaatttc atggctccca ttaagcttaa
     4141 aaatgagaac ttttgctggt aagcgtaggt aaaggcttca gtgatacatt cagccgaata
     4201 agcctttaaa atctcttgat cataataatc atgcgccacc aaataacgcc atttctcctc
     4261 caaactatca aaggataggc tttgtgggta gacatgctcc tctaaatagc gctgaacagc
     4321 ttccttatca ctgtcaaagt gataggtacc atctgctcgt ttaaagcgtg taagggcatt
     4381 taatgagagg taggactctt tttgtgacat tcttttttcc tttcgttaca atgtgtgatc
     4441 attctacggt aataatcagt atgacagcca atcacctgct aaaatcgcct gcaccttgag
     4501 gacatctctt tgtgtcccca gcaattcaaa ttggtgcaaa agcggcacct gcaatttttg
     4561 tgcaatgatt ggtcctgcaa tggcaaaggt atcaccaaag ttagtattgc cagaggaaat
     4621 aaccccctta cagtgccttc gattgttagc attgtttaga aaatgaatca cctgcttggg
     4681 aacagctccc ttgctgtctg agccaccagc agcataggta gggacaatca aaatataatc
     4741 ctcatcaact aatagaggct caccagtgac tggaattctt agagctctta catctagctt
     4801 ttgcacaaag cggtgagtgt tgttagatcg cgatgaaaaa taaacaagca ttatccttgc
     4861 agccatctta aaactcccaa tcgtcatcag tggtttcctc agtaactccc atcacgtaag
     4921 aagagccatt tcctgagaaa aagtcatggt tctcatctgc tcgcgctgat agctgagcaa
     4981 atacctcagg ggaaatacgt gtttcctcct cagtaaaggg agaatcatac cctagatttt
     5041 gcaaaaattt tccggcatta tagacgctaa agcgaatcgc atcgtcagca agatcaaagc
     5101 cgtcatacaa ttccctcagg taagccttct ccaaatcaat cagctgataa agcaggtcaa
     5161 acacaaaggc cttcatctca gcctgctttt caggacttag ggctgccacc ttttgttgat
     5221 acttgtagcc actgtaataa ttgtgaataa ccttatctct caggattaag cgaataatgt
     5281 ctgaggtatt gggcattttc cctctagctg acaggtaaaa aggaaggtaa aagccaccat
     5341 acagcaaaaa gccaggcatc atagctgctg cgaccttaga cttcagaggg tcatcaccag
     5401 tataatacgg aatcaacaca cgtgctcgct cctgtaagct ctctgttgac accacccaat
     5461 cgtgggcctc ctcgatctgc tgactgctgc acagggtcga aaagattgtc ccataggacc
     5521 tagcatgaat agcaaccata aaggcaaaat tagtataaat cacctgctca tgatcggtca
     5581 gggaatgttg aatttgtgct acatctccaa ctgttgcttg aaccgtatct agcaaagtca
     5641 agccagtata ggttcttgtg attagccttt gccaatcctc ccccaaagaa cgccaagaat
     5701 taaggtcatt agaaacagga accttctcag gtagccaaaa attttgcgtc actcggttcc
     5761 agacctcaag gtccttatcg tcattaagct gattccagtt gacagagcgc aggctttttt
     5821 tgctttgaga cagggcgtag tcaattggtg actgtgatcg gtcgtaataa tattgggtca
     5881 tgttttctcc ttcaggcttg atagtcgcaa tatcaatcct tgagctgcca agccttctac
     5941 agctttagga ctagggaaga ctgctaagtt cacatttagg caacacaaaa aaacttgctc
     6001 taaagggcaa tcctgcaggc taatgatgat ttcttgctga tgatccctaa ccagtcagca
     6061 actgctttgt aagcgaggct aagcccgcct ttttctccgg ctgaattaag tatacttaat
     6121 tcttatgttt gttataataa cacaatatat agtgctttgc aatatttttt gatacaatat
     6181 atagattatt ttataaaaaa gaaatcataa aaggagctag cagcacctta acgaaagccc
     6241 tgtctgtatg ctcaccaatc ccctcaacta gcagacagct catatccaga ttaagcatca
     6301 gcaaagctgc tgcttactgt ccttgagtag cgtaaaatta gattttatga atatctctac
     6361 tgatgttccg aatcccatac aacaactcga tttttaaata attttctaga aagttttcaa
     6421 tatacttttc ttcaggaaaa ttatttaaaa gtcttttacg aataaactct gaaaaactat
     6481 ctgatggggc aactctcagc atatcttcca aaatcttatt tgctttacga gtaagtttta
     6541 cttctcgtct aacatttctt atgtcattta tcacgataac tcttcatgat tcctagtcgt
     6601 acaataaaca actgtacgcc gtacactata tgactaggaa ttaatgaacc taaacttgat
     6661 ctttgggttg tggtgagctc aggtattgtg gtcacaatac ctcaaaaata atgtcatcag
     6721 cctctttgaa attgttattt cactttgact gataatatta aaagcttgga gactctatcc
     6781 ctcctaaaaa tagtttaaac aattattctt attttttcta tcacaaaaaa caaacgaaag
     6841 tagttcttta tatggcttta aaacttttct agtgaggtaa ctgttgtatt cataaaaaag
     6901 acc
//
LOCUS       DARYSY010000075         6877 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYSY010000075 DARYSY010000000
VERSION     DARYSY010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6877
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..530
                     /locus_tag="TVR04_001772"
     CDS             <1..530
                     /locus_tag="TVR04_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEL1270443.1"
                     /translation="ELQKSINLDPDGFPTVWLAIDLLMFGDIVSILTIMSEKNIKQIC
                     QYYSCTPEELVSWLKCLNFIRNVCAHNSNVLDIQITTKPKLRSEWRNYIDTVKIKHNV
                     TKPSNKLSVIIAIVVYLVNTINSKYQWRKIQSSLKALCKEDDSRAKLLGFKDYDSVKA
                     MINGIKCTAFTNSKK"
     gene            716..916
                     /locus_tag="TVR04_001773"
     CDS             716..916
                     /locus_tag="TVR04_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1270444.1"
                     /translation="MSEEKLKAKVEQASGSLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            1053..1237
                     /locus_tag="TVR04_001774"
                     /pseudo
     CDS             1053..1237
                     /locus_tag="TVR04_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
     gene            1519..1722
                     /locus_tag="TVR04_001775"
     CDS             1519..1722
                     /locus_tag="TVR04_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1270445.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            1894..2355
                     /locus_tag="TVR04_001776"
     CDS             1894..2355
                     /locus_tag="TVR04_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1270446.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDRLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAIASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            2355..4796
                     /locus_tag="TVR04_001777"
     CDS             2355..4796
                     /locus_tag="TVR04_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1270447.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIKAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICKVTN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLRDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAIHTAVKLAQRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLAKEDKQPKLKPTAVTEDDMLHTLSRLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(5144..5230)
                     /locus_tag="TVR04_001778"
     CDS             complement(5144..5230)
                     /locus_tag="TVR04_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1270448.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            5570..6001
                     /locus_tag="TVR04_001779"
     CDS             5570..6001
                     /locus_tag="TVR04_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270449.1"
                     /translation="MKKSTKVFIALMILIGGLLMVFSLNGKITEEQQKRDLETSIAKL
                     LVHDYEGVKTIKFQGWGRSRETGSWGTTVVINGENEIGFSFAGLSSLEKIRGIVTDDD
                     IEKMEKPETDTKPRIMDRIDTINKTSLVGVTVIYSKDNQED"
     gene            6136..6567
                     /locus_tag="TVR04_001780"
     CDS             6136..6567
                     /locus_tag="TVR04_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270450.1"
                     /translation="MKKTTKAFIALMILIGGLFMVFSLNRKIIEEQQKRDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTIVVINGENEMDFSFNNLSGLKEISSTSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLERVAITYSHEKRS"
BASE COUNT         2186 a         1124 c         1551 g         2016 t
ORIGIN      
        1 ctgagttaca aaaatcaatt aaccttgatc cagatggatt cccaacagtg tggcttgcta
       61 ttgatttatt gatgtttggt gacatcgttt caatcttaac aatcatgagc gagaagaaca
      121 ttaaacagat ttgtcaatat tacagttgta caccagaaga acttgtttcg tggcttaaat
      181 gtttgaattt cataagaaat gtatgtgctc ataattcaaa tgtactggat attcaaatca
      241 caacaaagcc taaacttcgt tctgaatgga gaaattatat tgatacagta aaaattaaac
      301 ataacgtgac taaaccttct aataagttat ccgttattat tgctattgta gtctatcttg
      361 taaatactat taactccaaa tatcaatgga gaaaaataca gtctagtttg aaggctcttt
      421 gtaaagaaga tgacagtagg gcaaagcttt taggttttaa agattatgat tctgttaagg
      481 caatgattaa tggaataaag tgcactgctt ttacaaattc aaaaaaatag aattttttag
      541 caagagccgc ctgacactag cggctcttgc ttttttattt gttgtgtgct agtatatatt
      601 cataatccta aagctttcat aaaagctaat tttccccagc tatgtggctg ggttttttat
      661 ttgcttagaa ataatcaaag tgttattata aattaaaaat caaaggaggc atattatgtc
      721 agaagaaaaa ttaaaagcaa aagttgaaca agcttcaggt agccttaaag aaggtgcagg
      781 aaagctaact ggcgataaag agttagaggc aaaaggattt gttgaaaaaa caattgccaa
      841 aggtaaagaa ctagcagatg atgctaaaga agcagttgaa ggggcagtag atgctgtcaa
      901 agaaaaactg aaataaaaaa aacaaccgct cagattaatt tctgggcggt tgttttgtgt
      961 ttcacacatt ggcatatccg ttataacgga cttgttaaaa ttagtccatt aaaccagact
     1021 ttttgcgaat aataagataa ggaggataaa aaatgctaac atacgatgag tttaaacagg
     1081 caattgatga cggatatatc gcaggagaca cagtaataat cgtgtgcaaa aaaacggaca
     1141 gatttttgat tatgtgttgc cgcatgagga gataagagat tgggaggttg tgacagagga
     1201 gagagtagaa gaggtgacga gagagttaga acgctagtcg gtcaaaaatc ggtcaaacgt
     1261 catcaaaacc tttgttatta gtgtttttca aatccgtcta ccgccttaga ttgttaaagc
     1321 aaggtcagca tgactttgct tttttacatt ttagcaggtg gagtagaaaa gctgtcattg
     1381 tgagaggtat gtgttgacag tggctgccat tcgtgttaca ctgggcgagt aaattagttt
     1441 ttgaattagt agttgtgttt tggcatcttt atttctctct atgtttacaa atgcgttata
     1501 gaaaggaagt ggatgactat ggcacaaggt acagtcaagt ggtttaatgc tgaaaagggc
     1561 tttggcttta tttcaactga aaatggtcaa gatgtttttg cacatttttc agcaatccag
     1621 tctgacggct ttagatcgtt agacgaggga cagagggtga cgtttgatgt tgaagacgga
     1681 cagcgcggtc ctcaggcagt aaatatcact aaattgtctt aatctagtga gcagataata
     1741 ggggatgggt gttgtcaatg gcgcctgtct ttttacattc tagtgatttc catttgcttt
     1801 tagtgactgc tatttgatat aatgttagtc agttttagtc aaaaataaag gcttaaagca
     1861 gcaaatgaat cgttttagca aaggagtgac ggcatgccaa caaaaaatac ttccgatagt
     1921 atcgaagaat atatcaaaga attgttagcc caatcaggaa tcgcagagat caagcgctcc
     1981 atgctggcgg attcctttca ggtagtacca agccagatta attatgtgat caagactcgc
     2041 tttacagaaa gcagaggcta tgaggtagag agtaagcgtg gtgggggtgg ctacattcgt
     2101 attgctaagg ttcatttttc agataagcac cacctgatcg gtacgttgat cgcttctatt
     2161 gatgatcgtt taagcgagca ggcctttaca gattcgattc agctgctttt tgatgagcag
     2221 ttattaacag aacgcgaagg aaacattatt ttagctatag cgtctaatga tgttttggga
     2281 catcaagcac cagaaattcg tgctcgtatg ctttatcgcc tattgcaacg aattgataga
     2341 aagggaagca attagtgatg atttattcat taaagatgca agacattttt aatcaggctc
     2401 aatttcaagc agagcgcttt gatagtcctt accttgagac ctggcatatt ttattagcta
     2461 tggtagctgt tgaccattcc ttagcggcca tggtgttaag cgaatttgaa cgaaagatta
     2521 aggccgaaga gtatgaggct gctgctattt tagccatggg aaaaagtccc aaagaggtga
     2581 cttctgtcca attcaagcca caatccaagg ccttatcaga aatactagca tttgctcatg
     2641 ctatctgtaa ggttaccaat gagcatgagg ttggctcaga gcatgtgctt tttgctattt
     2701 tgctcaatcc ggatattatg gccagtcgtc tgttagaact agcgggctac aggctcagag
     2761 attctggcaa aggagagcct cgctttgcag atttgcgtaa ggctattgag ctaaatgccg
     2821 gctatagcaa ggaaactatt aaggcgattc atgagttgcg taagcctaaa aagagtaaat
     2881 cagtaggcac cttttctgaa atgatgaagc cacagagtac agctggtgag ctatcagact
     2941 ttacaagaga cctgacagag atggcaagac agggcttatt agagccagtc atcggacgag
     3001 aaaaagaggt gtcacgtatg gttcaggtgc tttgtcgtaa gacgaaaaat aatcctgttc
     3061 ttgttggtga tgcgggtgtc ggaaaaactg ctctagctta tggcttagcg cagcgaattg
     3121 ctaatggagc cattccttat gaattacaag acatgcgtgt cttggagctt gacatgatga
     3181 gtgtggttgc aggtacccgt tttcgtgggg attttgaaga gcgcatgaat caactcattg
     3241 acgatattga agcagatggt aagatcattt tgtttgtcga tgagctacat accattatgg
     3301 gatcaggaag tggtattgac agcacacttg atgccgctaa tattctaaag ccagcccttt
     3361 ctcgcggtac cctgcatatg gttggcgcta caactcaaga ggaatatcaa aagcacattg
     3421 aaaaggacgc agctctttct cgtcgctttg ccaagatatt gattgaggag cctagtgttg
     3481 aggacgctta tcagattttg cttggcttga agccttccta tgaacagtac cataatgtaa
     3541 caatctctga tacagctatc catactgctg tgaagctggc tcagcgctat ttgacaagta
     3601 agcagcttcc agactcagcg attgatctgc ttgatgaagc cagtgcgatg gtgcaaagta
     3661 tggttaaaaa gacgcagcct gactttataa caccgcttga tcaagccctg cttgatggtg
     3721 atatgagcaa ggtgtcggcc cttttagcca aagaggataa gcaaccaaag ctaaaaccaa
     3781 cagcagtcac tgaagatgat atgttacaca ccttaagcag gctatcaggt attccactag
     3841 aaaaactaac tcaggcggat agtaaaaaat acctaaattt ggaaaaggaa ttgcataagc
     3901 gtgttgttgg tcaggaaatg gctgtttctg ctattgcacg agccattcgt cgtaatcagt
     3961 caggcattcg cacaggcaga cgcccgattg gctcctttat gtttcttggt ccaaccggtg
     4021 tcggaaaaac agagctagca aaggccttgg ccgaattact ctttgatgat gagtcagccc
     4081 ttattcgttt tgacatgtct gagtacatgg aaaaatttgc agcctctcgt ctcaatggtg
     4141 ctcctcctgg ctatgttggc tatgatgaag gaggcgagct aaccgaaaag gttagaaata
     4201 agccttatgc cgttcttctt tttgatgagg tcgaaaaggc tcacccagac atctttaata
     4261 tcctgctgca ggtccttgat gatggtatgt taacagatag tcgtggacgt aaggttgatt
     4321 tttcaaacac gattattatc atgacgagca acctaggagc aactgctcta agagatgata
     4381 agacggttgg atttggcgct aaagcgatcg gtcatgacca tcaagcaatg gaaaagcgta
     4441 ttttagagga attgaaaaag gcttatcggc ctgaatttat caacagaatt gatgaaaagg
     4501 tggtcttcca cagcctaaca caggaaaaca tgcgtgatgt ggtcaaaatt atggttaagc
     4561 cgctgattgc agccttggca gaaaagcata ttagccttaa gttccagcca tcagctctca
     4621 agtacttgtc tgaagctggt tacgatgttg aaatgggggc tcgcccactt cgtcgcacct
     4681 tgcaaacaga ggttgaggac aggttagcag aattaatgct gtcaggagag ttatcaagcg
     4741 gtcaaagcct caagattggt gtatcacgtg ggaagttagc ttttgatatt gcttgatgac
     4801 tgattgcttg ctattaagtt aagagctttg agagggtctg agacaaagtt tctcagactc
     4861 tttttatcgt gtagtgatga agtaccagaa tgagagttta aagcgtagca gatagatagg
     4921 atttaatttt aatcgaatgt agcgaaaaat agggattttg agaaattggc taccaatcta
     4981 gctacctaaa tagatctcat ttgactactt ttcttagttg ggatataatg gaggtagaaa
     5041 aagggcagtt gctcaaaaca actacccaac gcagaaccgt ttaagacggt agcttatctt
     5101 aattataaaa aaataaccga gaactcgcca aagttaaaga cggttatttt ttattgctca
     5161 tttttacgat aataacaact aagccaatga gtgaaagtag aaaactaccg aacccaagca
     5221 tgagttgcat tgcctcgtaa acggacaata ttcgctcctt tctctttgga ttttagcact
     5281 tacagtcata agcaccacca cctttcagaa attagagcca ccgccttaac ttttctgcag
     5341 aaaccattat accatagtca tatgaaatag ctgaccgatt ttgaaaattc aggtagcttt
     5401 ttttgtgtcc tctgcttgca gggaagaaat ataccctaaa atcgttttta agcgattgtt
     5461 tgttgagatg gtatattttt tatcgaatac gacataaaaa ttgaatatgg ttattctatg
     5521 acttcttatt tattgtatac tcttattaga gattaaaagg agaactttca tgaaaaagtc
     5581 gacaaaagtt tttatagctt taatgattct cataggaggg ctacttatgg tatttagttt
     5641 gaatggtaaa atcacagaag aacaacaaaa aagggatttg gaaaccagca ttgccaagct
     5701 gctggttcat gactatgaag gggttaaaac cattaagttt caaggctggg gacgttctcg
     5761 tgaaacaggt tcgtggggga cgacagtagt tataaatgga gaaaatgaaa taggcttttc
     5821 gtttgccggt ttatcaagtc ttgagaaaat acgaggcatt gttactgatg atgatataga
     5881 aaagatggaa aaacctgaaa ctgatactaa accaagaatt atggatagga ttgacacgat
     5941 taataaaaca tctcttgtag gtgttactgt catttattca aaggataatc aggaggatta
     6001 atatggtgat atcggatagt agttataatg agttagcaga acagctctgt aatgtcgaac
     6061 ctagcaaagc aaagtcgaat gatgtagttc agtatgacct tgataagcag gaaactagtt
     6121 aaaaggagaa ctttcatgaa aaagacaacc aaagctttta ttgctttaat gattctcata
     6181 ggagggctgt ttatggtatt tagcttgaac cgtaaaatca tagaagaaca acaaaaaagg
     6241 gacttggaga ctagtattgc caagctgctt gttcatgact atgaaggggt taaaaccatt
     6301 aaatttcaag gctggggaca ttctcgtgaa acaggttcgt ggggaacgat agtagttata
     6361 aatggagaaa atgaaatgga tttttcattt aataatttat ctggattgaa ggaaatcagt
     6421 agtacttctt accatccaga tacgtttaag ctagttgaga aaaatagtct ggaagaaatg
     6481 gggcctgtga aatatagaat taaagacatt gaaaaagttt ctttagagag agtggcaatt
     6541 acgtattctc atgagaaaag gagttaatat gatgatatcc gatagtagct ataatgagtt
     6601 agcaagacag gcttataata tcgaacttag caaagctaag tcaaatgatg cctctatgtt
     6661 ttaacggaaa gactattagc aggggagttt aacgcataac ggatagcatt atggaaaact
     6721 gtttagcttt atttttagct catttttatt gtatactatt attagagatt aaaaggagaa
     6781 ctttcatgaa aaagtcgaca aaagctttta tagctttaat gattctaata ggagggctgt
     6841 ttatggtttt tagtttgaat aacccagata tcaacca
//
LOCUS       DARYSY010000076         6695 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYSY010000076 DARYSY010000000
VERSION     DARYSY010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6695
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1675
                     /locus_tag="TVR04_001781"
     CDS             <1..1675
                     /locus_tag="TVR04_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270451.1"
                     /translation="FNVHQLNGRDQNFSNRKAVVSEIRRRVLALKKTQEAEKKAEEAL
                     KTEKLEKQSLNHELEGTRKALKSVIEGSHKLEQQLATEQRKVQQAQDKAKKAQEEASQ
                     AEETAQQAKTDKEKAETEAKKAKEKAKTAEGKAKEAETAKKKAEDAAKKATEQANAAK
                     EIAHQAQEKAKQLEQATQKANQKANLAEKAKKDLETQKEKLEKDIEQATEAKNKAEQK
                     LKDLQDSASQGSELSKQLLKEKEELTTKLQDLQKQAKEKSTEIEKLKQELEANKQNSG
                     QLGQKEKELQEQLNKVQKELKQKEMELEKAKEQLKQEQKPHEGGGDSDASKAKIAELE
                     QQVQTLTKEKADLSSTLESTKAQLSETQAKLSETQKQLTAAQEKLTTLEAEKVALQHQ
                     VETISKQLSEARDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQNMQSHQGQDKPKD
                     PKTPETPKDPKVPEDPKTPEKNDQQQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSSQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLSLSPRRKKNQNNR"
     gene            2093..2935
                     /locus_tag="TVR04_001782"
     CDS             2093..2935
                     /locus_tag="TVR04_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1270452.1"
                     /translation="MVSVLSRVIKGMIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFIENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQADWLWLVLTFVLSGLGLYFLNDLVGTIPASFAAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLIGTFLPIAIGGLLTMLAFSKVMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNEEAISYAGAGLGTWLMAMLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(3022..3648)
                     /locus_tag="TVR04_001783"
     CDS             complement(3022..3648)
                     /locus_tag="TVR04_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1270453.1"
                     /translation="MKSIIEHYQARPLGEERCYAVCLPLIWQEGRWQVLYEIRSQHVS
                     QPGEVSFPGGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEIDYLVQPTRSIHCFVA
                     ELVIDDWRRLRVNEEVDSLFTVSLEKLMAQAPVAYPLQMQSIISSDFPLDRIPNGEQY
                     RLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDLLKNEC"
     gene            3850..4176
                     /locus_tag="TVR04_001784"
     CDS             3850..4176
                     /locus_tag="TVR04_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1270454.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKTTLDGIIEGR
                     LRHDKS"
     gene            4163..4603
                     /locus_tag="TVR04_001785"
     CDS             4163..4603
                     /locus_tag="TVR04_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1270455.1"
                     /translation="MTRAEYLAELDKYLRKLPKADYYEAAENSRQLELNEGRIKDSSI
                     TVADTKEENDYTEPSELAINHATIKGKNTINGGDININTTLANLRDIAYHVTTRGSIK
                     LSSHFSNAKLNTDAVTGATSFHSDIANAVNQLDITVNKGDLSIH"
     gene            4622..5677
                     /locus_tag="TVR04_001786"
     CDS             4622..5677
                     /locus_tag="TVR04_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1270456.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEIDSKTRSESNSQELEPIVDIRYSLL
                     NHDLTIEAADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGENDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCHIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(5746..6695)
                     /locus_tag="TVR04_001787"
                     /pseudo
     CDS             complement(5746..6695)
                     /locus_tag="TVR04_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611511.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2316 a         1428 c         1217 g         1734 t
ORIGIN      
        1 atttaatgtt caccaactta atggaagaga tcaaaatttt agtaatagaa aggctgtcgt
       61 cagtgaaatt agacgcagag tattggcttt aaaaaagact caagaagctg agaaaaaagc
      121 ggaagaagct ttaaaaacag aaaaactaga aaagcaatca ctcaatcatg aacttgaagg
      181 aactcgaaaa gctctcaaat cagtaattga aggttcacat aaactagaac aacaattagc
      241 aactgaacaa cgaaaagtac aacaggcaca agataaagct aagaaagctc aagaagaagc
      301 tagtcaagct gaagaaacag cccaacaagc taaaaccgat aaagaaaagg cagagactga
      361 agctaaaaaa gctaaggaaa aggcaaaaac tgctgaagga aaggctaagg aagctgaaac
      421 tgccaaaaag aaggctgaag acgcggctaa aaaggctaca gaacaagcta atgctgctaa
      481 agaaattgct catcaagcac aagaaaaagc taaacaatta gaacaagcta ctcaaaaggc
      541 taaccaaaaa gctaatctgg cagaaaaagc taaaaaagat ttagaaactc aaaaagaaaa
      601 gcttgaaaaa gatattgaac aagctacaga agctaaaaac aaagccgagc aaaaattaaa
      661 agacctacaa gattcagcta gtcaaggcag tgaattgtct aaacagctgt taaaagaaaa
      721 agaagaatta acaacaaaac ttcaagacct tcaaaaacaa gctaaggaaa aatcaactga
      781 aattgaaaag cttaaacaag agcttgaagc taataaacaa aacagtggtc agctaggtca
      841 aaaagaaaaa gagcttcaag agcagttgaa caaggttcaa aaagagctga aacaaaagga
      901 aatggagctt gaaaaagcta aagaacagct gaaacaagaa caaaaacctc atgaaggtgg
      961 cggagattct gacgcttcca aggcaaaaat cgctgaatta gaacaacagg ttcaaacact
     1021 aaccaaggaa aaggcagatc tgtcatcaac ccttgagtca acaaaagctc aattgtcaga
     1081 gactcaagca aaactatcag aaactcaaaa acaattgact gctgctcaag aaaagttaac
     1141 aacacttgaa gccgagaaag tagcgcttca acatcaagtt gagaccattt caaaacagct
     1201 atcagaagcg cgtgacctca gcgaaaagga aaaagcagca ctccaagagc agattaataa
     1261 gctaaaggct gagattgagc aaaagaccaa ggaaattgaa gccttaaagc agaacatgca
     1321 atcacatcaa ggtcaagaca agccaaagga tccaaagaca ccggaaacac caaaagatcc
     1381 aaaagtacca gaagatccaa agactcctga gaaaaacgat cagcaacaag cgcctgaaaa
     1441 acgtagtgtc ccttggactg ctcttacacc agctaagcca attgacacta ccaaagctcc
     1501 taagagctca gcaccaagct cacagactgg ggcagcaaca cctaaaaaac aattaccagc
     1561 aactggtgat acagcgacac ctagcttctt taccgctgct gctatggcag tattggctag
     1621 cgtcggtgtc ctaagtctct cacctagacg caaaaagaat caaaacaacc gttaatgtag
     1681 agactctcat atctggattg aataacagca aactcgacat gagcaaaaac aaatgtctaa
     1741 ccaaaaatca ctgacattag tgctttaaac aaagcctttg agtcaagcta aacaggctgt
     1801 cttgcctatt ggcttgactc attttatgct tgtgaaacac cccaaaagtc aaacccacct
     1861 tgtcctccat tttaaaccta ctcttttttc ctataccccc tttagcttac gcaagaaggt
     1921 gcctaatcat cacttttggt agcttcgatg ctctatataa atggatcaac aaagataaat
     1981 catacaaaac tgcgagttgt tcctatagtc acgatagctc ttacagatat gaaaagttaa
     2041 tacagctgtt aaaaatatgg tacaataggg gtacgatttt taggaggcat gtatggtttc
     2101 agttctttca cgagtgatta agggaatgat tattgcgctt ggctttattt taccgggagt
     2161 atctggagga gtattagccg ctatccttgg gatctacgag cgcatcattg cctttttagc
     2221 tcatatacgt gagcatttta ttgagaatgt tctctttttc ctgcctgttg gggttggtgg
     2281 tattttagga attgccctct tttcttaccc tgttgactat ctgctcaagc actaccaggt
     2341 accagtctta tggggctttg ctggggccat cataggaacc gtacctagtc tgataaagac
     2401 ttcgacaaaa acatctcagc gtgaccaagc cgattggctc tggctcgtat taacctttgt
     2461 cctatcagga ctgggacttt atttcttaaa tgatctcgtt ggaacaatac ctgcaagttt
     2521 tgccgccttt gtcctagctg gtgccttgat tgctttaggt attttagtac ccggtcttag
     2581 cccgtctaat cttttactaa tcttaggact ttactcaccc atgctaattg gctttaaatc
     2641 acttgatttg ataggaacct ttttacccat tgctattggt ggcttattaa ccatgctagc
     2701 cttttccaag gtcatggatt ttgctctcaa gcactaccat tcacgcgttt atcactttat
     2761 tatcggtatc gtcctatcta gtaccctgct cattttgatt ccaaatagca gcaatgagga
     2821 agctatctct tacgctggtg caggtcttgg cacctggcta atggctatgc tattatttgg
     2881 ccttggtgtc tggcttggtc tatggatgag ccagcttgag gaaaaataca aatagcagtc
     2941 gatacagcag caaataccac taacagtagt attaagatca aaaaacgaat gactagctct
     3001 cagccttatc accagctgtg actagcattc gttttttaat aggtcatcat gctgccttgc
     3061 ctctgtcacg atttctataa aacggttcgt caattgagca gttatccccc agataggctt
     3121 ttctaaatgc tcatagagta atacctgatc ttgcatgtac ctcaacctgt actgctctcc
     3181 attagggata cgatccaacg gaaagtctga cgagattatc gattgcattt gtaaaggata
     3241 agcaacagga gcttgcgcca tgagcttctc cagagacacc gtaaacaagc tgtcaacctc
     3301 ttcattgacc ctaagccttc tccaatcatc aataaccagc tccgcaacaa agcaatgaat
     3361 gctacgagtc ggctgaacta aatagtcaat ctcaccccag acatgaacct gctcaggctc
     3421 tatattgagc tcctctaccg tctcacgaat agccgcctgc tgataggtct caccctcctc
     3481 cacgcgccca ccaggaaaag aaacctcccc tggctgagag acgtgttggc ttctgatttc
     3541 atacaagacc tgccacctcc cttcctgcca aatcaaaggc aagcaaaccg cataacatcg
     3601 ctcctcaccc aagggcctgg cctgataatg ttcaataata ctcttcatct gtccttctcc
     3661 ttatcatatc cagcactagc tacttccata gtataaaata gcaatccttt ggtcaagaaa
     3721 tggctacgat tgctctctat aatatataaa atttttatat ataaaatatt gacatatcaa
     3781 aacagaagct ctatacttaa tatataaaat aattatatat ataaatacga ggcaagaagg
     3841 gagcaccaga tgtattttcc agtatctgct accttgattg aatttttgat tttatctatt
     3901 gtcgacaagc atgattccta tggttatgat atcagccaaa ccattaagct tgtcgctaat
     3961 atcagggaat caaccctata ccctatttta aaaaagctag agaaatcaga ctatttaact
     4021 acctatagtc aggaacatca aggtcgcaag cgtaactact acaccattac agccaaaggc
     4081 gaaaagcagc tgattttctt aaaggaagaa tggcaaagct acaagactac cctagatggc
     4141 attattgaag ggagattaag gcatgacaag agctgagtac ctagcagagc tagacaaata
     4201 cctacgaaaa ttacctaaag cagattatta tgaagctgct gagaactcaa ggcagctaga
     4261 acttaacgaa ggcaggatca aagactcttc tatcactgta gctgatacaa aagaagaaaa
     4321 cgactatacc gagccctctg agcttgctat aaatcatgcc acaatcaagg ggaaaaacac
     4381 gattaatggc ggcgatatta acatcaatac cacattagca aatctaaggg atattgctta
     4441 ccatgtcaca acaagaggca gtatcaagct cagctctcat ttttcaaatg ccaagcttaa
     4501 cacagacgca gtaacaggag ctacttcatt tcactctgac atagctaatg ctgtcaatca
     4561 acttgacatc actgtcaaca aaggggactt atcaattcac taatcaagag aggatatcgt
     4621 aatgactaaa caagactttc tagacaagct aaagcagcag atcaaccatt tacctcaaaa
     4681 ggattaccaa gaaatcattg accactttac agagtatttt gacgaggctg gtcctgacca
     4741 tgaacaagct attcttaaag aactgggaaa tccagaggat atcgccaaag agctattaaa
     4801 agccttagac ctccctgaaa aaacagacga agatgattgg acgaattggg agattgacag
     4861 caaaacaagg tcagaatcaa actcacaaga gcttgagcca atagttgaca ttcgctatag
     4921 tctgcttaac catgatttaa ccattgaagc tgctgacatt ccttacccta ctatttcata
     4981 tgatgataat cgcatcacaa taagccaaga tagtgacggc atgctcaata tcattgaaga
     5041 ctcagcagta caaacaatac agtatggctt tcatttccta gaccgctggc tggcaaaata
     5101 tcaacccatt accttgacac tacctgtcaa ccaccacctg aaaaaaatct ctggggaaaa
     5161 tgacaacaac gatgtcacca taaggcatat acattgtgat agcattgtct ctaacactta
     5221 caatggaacg atttctatca gtcatttatc agatagcact gtcaacctaa gcagcaaaaa
     5281 tggaaacatt attttagagc attgccatat ccagtctagt aaatgtcaag ccaaaaatgc
     5341 taacctcagc tgtgacaata gcaccctaat aaattgccag ctgaacaata acaatggaaa
     5401 catcagatta gaagcaagtc agctaacaga aaccttcatt gaaaacaaaa acggtaatat
     5461 catagggcag cagctgtctt tttccaatga catcactatc atcaataaga atggaatcat
     5521 tgacatcaat tgtcctagag aaaacctcat ctactatgat gtaaaggctt caaataataa
     5581 tggatttgta acgattagtc aagaagcagg tcgtcaaaca ccctttaaag cacagcttac
     5641 catttccaat aataatggtc ttatctccgt aagctaaacc agccataaaa aaagcttcta
     5701 gaaagagctt aaactgaaat gacccccaaa agttagacaa aatagttaag ctaaggattg
     5761 agttctgtat tgtacagggc tcagtccttt taatgttagt ttgattcgtt tgttgttgta
     5821 ataatcaata tactctgaaa tagctattgc caaatcctca agagaagtaa actctttctc
     5881 aaatccataa aacatttcta tcttcagcgt tccaaagaat gattccatca taccgttatc
     5941 taaactgttt cccttacgag acattgagga tttcattcca cggctctcaa gaaaattatg
     6001 atagtaaaca tgttgatact gccaaccttg atcactatgc aaaatagtat cttgataagt
     6061 tttttcagga aaggcttcgt taagcattgt ttgtagttgt tgtaagtttg gtgatacaga
     6121 gagattataa gcaataatgt cactgttata gccatcaaga actggtgaga gatagagctt
     6181 ctggtcacta gcaggaatgg aaaattcagt cacatctgtg tagcacttct gaagtggttg
     6241 tgtagctttg aattgacgct taatcagatt atcagctttc ttaccaactt ctcctttata
     6301 ggaattatag cgacgtttcg cacgaatccg agctttcaaa ccaagttcag tcattaagcg
     6361 ctgaactttc ttatgattaa cataaagccc tcgattttta agctcaagat gtactctacg
     6421 gtagccatat ctccctttgt gctcggcata gatgtcttga attgtttctt ttaagtcgct
     6481 atctttatct ttttgagcta accgtttaag gtggtaataa tacgttgaac gagatagatt
     6541 cagaatatca agcaatatcc ttaggttaaa ttctttgatc aatccctgaa tgatttccgt
     6601 tgctcttcga gctttgcctc gtccctcaag cggtattctc tcagcttttt tagtacagca
     6661 atctccgctc taaggtattc attttcatat tggag
//
LOCUS       DARYSY010000077         6620 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYSY010000077 DARYSY010000000
VERSION     DARYSY010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6620
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            223..834
                     /gene="rpsD"
                     /locus_tag="TVR04_001788"
     CDS             223..834
                     /gene="rpsD"
                     /locus_tag="TVR04_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1270457.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(940..1242)
                     /locus_tag="TVR04_001789"
                     /pseudo
     CDS             complement(940..1242)
                     /locus_tag="TVR04_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            1756..2066
                     /locus_tag="TVR04_001790"
                     /pseudo
     CDS             1756..2066
                     /locus_tag="TVR04_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2092..2437
                     /locus_tag="TVR04_001791"
                     /pseudo
     CDS             2092..2437
                     /locus_tag="TVR04_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058801.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
     gene            2542..2829
                     /locus_tag="TVR04_001792"
     CDS             2542..2829
                     /locus_tag="TVR04_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000543070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1270458.1"
                     /translation="MQILEKNTQVNFKTNSDLLEKAKAVITAQNLDMTASFNLFLENI
                     VQNNTLPFETDADKERAELLADLRAEIAQSFDDLEHGRVYNASEVRANLGI"
     gene            2819..3166
                     /locus_tag="TVR04_001793"
     CDS             2819..3166
                     /locus_tag="TVR04_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1270459.1"
                     /translation="MVSDHKPYSLIIPETVQEQLRSIKSYIATAYFSEQAGANTVNNI
                     LYGLERLEFFPEAGFNADERVGEAVYPPYNTRCIVLGDYLAFYHILEDRKAVFVSDIL
                     HSKQDYIRLFRKK"
     gene            complement(3596..4129)
                     /locus_tag="TVR04_001794"
     CDS             complement(3596..4129)
                     /locus_tag="TVR04_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1270460.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSGF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEREYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            4262..6541
                     /locus_tag="TVR04_001795"
     CDS             4262..6541
                     /locus_tag="TVR04_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1270461.1"
                     /translation="MLEELKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKI
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVTARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTGLGHLAADMPAYLDGVSRLSKGANHLNAGLTQLALESDL
                     SQDKQANIQALMTNLPKLNQAIQQLNTNLPLSLAPNVDSEAIAKHLADMTRLVQELVV
                     DDTADKNNQLAALQATATYQGLSSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSEE
                     LETMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQLL
                     SGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAFG
                     ANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSEK
                     DKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGMI
                     STVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVGWDARYGAFASLIM
                     LLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGFL
                     LSFMAIGVLIYRPKDKQSS"
BASE COUNT         2002 a         1229 c         1391 g         1998 t
ORIGIN      
        1 ttgatgatac aatattaaaa atgtaaaaaa accttgaata aaagcctttt tcatgttaca
       61 attggctttg tgtgaaataa cagcagaaaa atatgaagct cgtcaacagg cggttaacta
      121 aattgagtaa cctttgctgt ttaggcgaaa acctcctgca cgaatcagga tttttcaaac
      181 agttatttcc tcgttatatt tttttagagg aggacatgat acatgtcacg ttatactggt
      241 ccatcatgga aacaatcacg tcgtcttggc ttgtcattga caggcacagg taaggaattg
      301 gcacgtcgta actacgtacc tggtcagcat ggccctaaca accgcagcaa gctttcagaa
      361 tatggcttgc agcttgctga gaagcaaaag cttcgctttt catatggtat gggggaaaag
      421 caattccgta acctattcgt acaagctaca aaaattaaag aaggaactct tggtttcaac
      481 tttatgcttc ttttagagcg tcgtcttgac aatgtggttt accgcttagg tcttgcaact
      541 actcgtcgtc aagcacgcca gtttgtcaac catggtcata ttcttgttga tggtaagcgt
      601 gttgatatcc catcattccg cgttgagatt ggccaagtca tctctgttcg tgaaaaatca
      661 atgaaggttc ctgcaatcct tgaggcagtt gaagcaactc ttggacgtcc agctttcgtt
      721 tcatttgacg ctgaaaagct tgaaggatca ttaactcgcc tcccagagcg cgacgaaatt
      781 aacccagaaa tcaatgaagc acttgtcgtt gaattctaca acaaaatgct ttaattttaa
      841 gattaaactt acagaaagcc tacaaccgtg ggctttttgc cttgtcttaa atcgttgatt
      901 tctgggtttg cttacctttt tgctaacctt gaatttcagt tagatagatt gtagagcttt
      961 ttcgtagaac gagacggctt tttttgcgtt ctcttttgag agatggctgt atgtatccat
     1021 tgtcatggat agggtggagt gacctagacg gtgttgcagt tccttataag gtattccaga
     1081 gttaagcagt aaactagcgt gagtatgacg gaatccgtga aagcctatgt tagttactcc
     1141 agctctctta aaatgggttc ttaatcgagt ttgtagagtt cgattacttg ggtaatcatg
     1201 gataaagtca gagaatataa ctatttcagt acgtcctaat tccacatgtc cgaccttcac
     1261 gtcgtcactg tacatttttt cttgcgttag gatttagaaa ctataaaaaa acaatcataa
     1321 aaccttgata taatggtgtt tgttaaggtt tcaaatccta ataaatacag taaaacacac
     1381 tagaaaacag taagtaagga aagatcatat tatggctagc cccccttatt tttgaacggg
     1441 ggtatattgt tcggaaactt aagaacgcgc cctcttcctc gcacaaaatt ccctttttga
     1501 aatttttaac aaagattcaa agccttattc taaaggattt cacagataat tttagctaag
     1561 aaccctacta caaggaataa ctctctcagg ctaaaattaa gcatggtttt agcgcttcta
     1621 tctagtaggt tgataagttt atattgctag cttcaaaaaa cacttagaga ctatttttga
     1681 agctaaaaaa gccagctcac gctagctccc ttgttaataa ttcgataaat ctattttacc
     1741 atagaggagc gaatcatggg ggctaaagaa caacttaaag aattgaagcc actctttgct
     1801 ttaatgacct tattcgagga gcaacgagat aaaaatatta agctgataaa tacttttcat
     1861 aacctcgagg tactaaagga catgaaaaag gtactgccaa gaaactcttg tatttaggca
     1921 aagaacgtga taagagacta gccatgattg ccaccttaca aaatgagaaa cagatagctg
     1981 ttattaaggc taggtatgtg gacgacttat catgggacga gctacctgat aagttaggtt
     2041 attcaaggaa tactgttttc aaatgacaca gagaagcttt aaagatatta gatgagcaag
     2101 aagaatgcca ttcgtaaatt aaaaaagttc catagatggc aacgtgtcgc caatagcttt
     2161 aatttaacgt ataacaagcg ttacaagatt acatccacga gcagaaaacg ccttgaaata
     2221 agccgagaat gcgctctaga ggagctagac gctattaagc atgccattaa caaactatct
     2281 aagctagaat acaggaaaat actaattgaa tgctacttga tcagtgagaa aaaacctcaa
     2341 caggacatcg tagaacagct taataagaac caaagctggc actatgagag ctttgcttga
     2401 gtcttcggag cattataggg gtggagtgtt aaaataatct gggcaaatat cattgctttt
     2461 tgaacatcag taagcatgca actatatatg actatacata tatagttcat agtgttataa
     2521 tacctttaag gaggtgctac tatgcaaatc ttagaaaaaa atacgcaggt taactttaaa
     2581 accaacagcg atttactaga aaaagctaaa gccgttatca cagcgcaaaa tcttgatatg
     2641 acagctagct ttaatttgtt tttagaaaac attgtacaaa ataacacctt gccttttgag
     2701 actgacgccg ataaagaacg ggctgaacta cttgcagact tacgggctga aattgctcaa
     2761 agctttgatg atttagaaca tggacgcgta tataatgcca gtgaagtgag ggctaacctt
     2821 ggtatctgat cacaaacctt atagccttat tattcctgaa accgtacagg agcagctacg
     2881 gagtataaaa agctatattg caactgcgta cttttcagag caggcaggcg ctaacaccgt
     2941 taacaatatc ctttacggct tagaacgcct tgaatttttt ccagaagcag gatttaatgc
     3001 agacgagaga gtaggagaag ccgtttatcc gccctacaat acccgttgca ttgttttagg
     3061 ggattaccta gctttttatc atattttaga ggacagaaaa gccgtctttg tatctgacat
     3121 tctccatagc aagcaagact atatcagact gttcaggaaa aaataaacgc ttgtagaaac
     3181 aagacaactt aaaaagcacc tttttggagt gccagttctt gtttgttgaa ttcataactt
     3241 agagctactg aaaggctctt ttttgcttcc ctttttgcga actttggggg agtgtaatga
     3301 taagttattt ggttagaaag cctgtcatat cagggtttaa ggagtgtaaa gaacgtgtaa
     3361 agctaagtaa tcttaactgt ataacaaaat gctttaagat aagactttat attgtaagaa
     3421 gcctacaaca gtgggctttt ttggttgagc tgttagctga tttaccaaaa ggttagacca
     3481 aaattctaac gattggagat cagtattgtt aggcataaag atcattataa actcaagaaa
     3541 aaatagttta caaagctatt tttttggtgc tggatttggc atcatcagcg tagggttatg
     3601 ttttagatag catttttaag acgaaacgag tcatttcctg aggggattct ttttttcctt
     3661 tagcaatcca gctttggcag acaccgaaaa aggcatgtgc taggtagatg cttcggtatt
     3721 ctctttcggt tggggataag atgtccttac tgaacttgtc ctgaagatcg gtagtgatca
     3781 atagacgaac tttgttaatg ataaagcttt ggatttctcg ggtaccattg gaggatagca
     3841 gagcagatag tagttgctct cgcttgagaa attcaaatac ttctaaaaag gcatgctcct
     3901 tgttttggta ttctttttca aaaatgtatt ctaatttgtg aaagaaggtt tgctgatagt
     3961 aatcaatcat ctcatatttg tctttgtagt gagtataaaa gccagaacga ctaatgcctg
     4021 ccattttagc cagctgaaca gttgttacat catcgaagct ttctgttttt agtaagctca
     4081 ccattgcatt aagaatggcc ttcttggttt gctgcttgcg gctatccatc attgactcct
     4141 tttgaacact tgtagacatt atgtctaaaa agtttatttt ttaccttgta aaatgtcact
     4201 ttatttgtat aatatattct atcataattt ttgaacagta tgtctatttg gagaaaaaat
     4261 aatgctagaa gaattaaaag caataatcaa aaatcgtaag ctagtagtga caatgattgg
     4321 ggttgctcta gtaccagctc tctataattt gtccttttta gggtccatgt gggatcctta
     4381 tggtcgggtt gatcagttgc ctgtagcagt tgtgaatcag gataagcctg cttacttgaa
     4441 taacaagaga ctgactattg gtaacgatat ggtagacaat atgtctaaaa ataaggaatt
     4501 ggattatcat tttgtggctg cagataccgc acaaaagggc ttggaaaagg ggcgttatta
     4561 tatgacgatt acgctgccaa aggatttgtc acaaaaggcc actacgctat tagatcagca
     4621 gccagagaaa ctgattgtta gctatcaaac cagtaagggc catagcttta tcgcttctaa
     4681 aatgggtgaa tctgctatga atcacttgag agaggctgtt tctaaaaata taaggaagat
     4741 ctatatcacc tccgttttta agagcatgca tcagctccaa tctggtctaa aggaagcttc
     4801 aaatggcggt cagcaattag ccgctggctt agtaactgct agggcaagca gtcagctaat
     4861 gtcaaggcat ttgaacacct tatctgaatc aagtgctcgc ttgtctcaag gagcgggtaa
     4921 tctatctagt ggtatagctg cctatacagc cggtgttggt cagcttgata ccggcttagg
     4981 acacctagca gctgatatgc cagcgtatct agatggtgtc tctcggttat ccaagggtgc
     5041 taatcatcta aatgctggct tgacccaatt ggctctagaa agtgatctgt ctcaagataa
     5101 acaagctaat attcaagctt taatgactaa cctaccaaag cttaatcagg ctatccagca
     5161 gttgaatacc aatcttccct tgtctttggc accaaatgtg gactcagaag ccattgctaa
     5221 gcatttagcc gatatgacgc gtttagtgca ggagcttgtg gtagatgata ctgctgacaa
     5281 gaacaatcag ctagccgctc tacaagctac agctacctat caaggtctca gctctgagca
     5341 gcaggaggag ctgagctcag ctatttccaa tacttcaact aaagtaacaa tatcagcaaa
     5401 ggctatgttg acatcactgc aagccatgtc tgaggagcta gagactatgt caacaagtgc
     5461 tggtgtagct gatcaactga gggattttaa agcacttgtt aatcagctgg cttatcaagc
     5521 tgatcaaatc ctacctagta caggtaaggc cttgtcagag ctttcaactg gtttaagggc
     5581 tgttcactca gcaacaacag cccagctctt atcaggaagt caagctcttg ctggtggctt
     5641 taatcaattg acagctaaga atgaagctct tacagcaggc ctgtctactc ttgctacagg
     5701 ggcaacagct cttaaccatc aatccagtca attattagca ggtggacagc agcttacagt
     5761 aggcgctaat cagctagctt ttggagccaa tcagctctcc tctggcagct ctcagttgac
     5821 agatggcttg acaactctgt caacaggtct gtcaagctta acgacctcac tatcaaaagc
     5881 ttctgaccag ctttcaatgg cttgggtaga ggaccagaat gctgatatgg tatctgatcc
     5941 agtagcgtta tcagagaagg acaaggataa ggttaggacc aatggtattg gcatggctcc
     6001 ttatatgatt gctgtgtctc taatggtagt tgccttgtct acaaatatta tttttgcaga
     6061 ggccttatct ggtaagccga ttaaagatag atgggattgg gcaaagcaaa aattactgat
     6121 caatggcatg atttcgaccg ttggctctgt tattctttac gctgcacttc aactgctggg
     6181 ctttgaagct aatgacggta tcaagacctt aggctttatt atgctgagtg gatgggcctt
     6241 gatggcttta gtgactgcat tggtcggctg ggatgctcga tatggtgcct ttgcttcgtt
     6301 aattatgctg ttgctacagg ttggtgctgc gggtggttct tatcctattg agttgagtgg
     6361 tcagatcttc cagattctcc atccttatct tccaatgtct tatattgtct ctggccttcg
     6421 tcagacaata tcattaactg cccagatagg tttagagacg agtgtattag ttggcttttt
     6481 gttaagcttt atggctatag gagtgctgat ttatcgtcca aaggataagc aatcgtccta
     6541 gataatagct gagataacag gttatcgtta aacagtagat ataataaaaa agcttctaga
     6601 aattgtggtt tgaactgcac
//
LOCUS       DARYSY010000078         5726 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYSY010000078 DARYSY010000000
VERSION     DARYSY010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5726
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(292..1659)
                     /gene="rlmD"
                     /locus_tag="TVR04_001796"
     CDS             complement(292..1659)
                     /gene="rlmD"
                     /locus_tag="TVR04_001796"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1270462.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEDFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHRLVAID
                     DCLVQDQLTQAIVNRVTQLLDRHRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMIYVSCNTSTLARDLVSLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKLQK"
     gene            complement(1656..2624)
                     /locus_tag="TVR04_001797"
     CDS             complement(1656..2624)
                     /locus_tag="TVR04_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1270463.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDTLFGHETEFFSDDLEALL
                     NSMDNQSLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYESKN
                     YHRGDLLMEVPLMVGALLAGREELADDILVNLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQQYFQVFFEGAEGELTFLEELDLPLSNV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            2688..3464
                     /gene="recX"
                     /locus_tag="TVR04_001798"
     CDS             2688..3464
                     /gene="recX"
                     /locus_tag="TVR04_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1270464.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDNLTVTEDTIIRFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYVRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQPKLPSKALTDKIIEGLLNKGFSYDLTKGIVSQLSLEQDSQHIKDLLDQEFDK
                     LFRKYSRRYDGYQLKQKLYQALYRKGYDSDDINTKLNDYF"
     gene            3697..4230
                     /locus_tag="TVR04_001799"
     CDS             3697..4230
                     /locus_tag="TVR04_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1270465.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            4480..4791
                     /locus_tag="TVR04_001800"
     CDS             4480..4791
                     /locus_tag="TVR04_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1270466.1"
                     /translation="MAFQTTKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVDQQGIETILLPHEM
                     Y"
BASE COUNT         1828 a         1287 c          982 g         1629 t
ORIGIN      
        1 ttgtgtcgcg atcacaattt aagtatagca ttctagtatc atattttttc taaaagtctt
       61 aaacggtcgt tttttcatcg taaacggtca ttttcaatcg ttttcaaccg ttcaagacaa
      121 cattaactac cattcaggat tttcattgga taaatcgcta ttttttgact ccttgtcaac
      181 ccactaaagc tattaataaa aaaataagac agtagcctaa atgtgactac tgtctctttt
      241 atctaaagcc ttgatcggca agaaaagagc cagtcttttc caactaatca attatttttg
      301 tagtttttgt cgcttctgta gcttcactac agcctcggtc cttgctgtgt gtggaaacat
      361 gtcaacagat tgaatatata tcacatcata gacctgaacc aaggatacca gatcacgagc
      421 caaggttgag gtattacagg aaacataaat cattttggct ggctgatagt gtaaaatcgt
      481 ttgtaatagc ttgtcatcta ggcctgttcg agggggatcc acaatcaggg catcagcccg
      541 atagccttca gcgtaccagc ttgggatcag ctcctctgcc ttgccagtct cataataagc
      601 attgtcaaag cccaatgcct gcgcattttt cctagcatca gcaattgcct ctggaataat
      661 atccatacca cgaacagatc ttactttgtt tgcaactgcc agaccaattg agccaacacc
      721 gcaataagca tcaataatat gctcctcagc tgtgggctca agcgcctgaa ccacttgact
      781 atataaaacc tctgtctgtg tgggattaag ctgataaaag gctcttggcg acagggcaaa
      841 gctatgactc aaaacctcct cttgaatggt ctcctgaccc cagagaatct cagttttagc
      901 gccataaata tcactggttt ttgaagtatt gatgtttaaa gcaacagtcc tgatttgtgg
      961 aaatgcagca gtcagctcag caataagacc tgccagcctc acctctttac tgcttacaaa
     1021 aatcaactga acctgatcac tggcctgtgc cctacgaacc ataactgtac gaattccagc
     1081 tactctgcgt tcattataga taggaatcct atgccgatca agcagttgag tcacacgatt
     1141 aacaatcgcc tgtgttagtt gatcctgaac cagacaatca tcaatagcaa ccaagcgatg
     1201 gctcccttct gaaaataagc ctgccttgac ggagccacca aacgaacgcg tctgaaactg
     1261 taattttgct cggtaatgct gcggctctgc cattcctaag gtatgacgaa tctcaaaatc
     1321 ttcatacccc ttaggcttaa acttttttaa ggcctgccga atgatgtcat ccttaaagta
     1381 gagctgctta ggataggcca gatgcatgat ttgacagcct ccacaggtct cataaatgga
     1441 acaggccggc ttcacccggt ttttagaagc cttattaatc accaagagcc ttgcctcagc
     1501 aaaattgcgc ttaacagcag tcacttgaca aaaaacctct tctcccttca aagctccggg
     1561 aacaaagacc aaggtctttt tataaaaacc aattccctca ccattaatcc ccattcgctt
     1621 aatcttaagc ggtatttttt gctttatttt gacattcatt cctgactaaa tattactcct
     1681 aatcgcttaa gccttgctat catctgcttg ccaacacctg gaatatcaag aagctcttga
     1741 gttgtccagg cagaaaaatc ctccagagta tgaataccat actgattaaa caaattgaca
     1801 ttacttaaag gaagatcaag ctcctctaga aatgttagct cgccttcagc tccttcaaaa
     1861 aacacctgaa aatactgctg caggtaatat tgtgcagtca tcaatagcgg taggatatta
     1921 aaaaaggcaa ggtaaatact tgataagctg tttggctcgt agctctccag ggcaccagca
     1981 gctaaaatat catctatcgg aaaggctttc tgtctgacaa ttgccacaaa gtctggcacc
     2041 gtttcagcaa ggttaaccaa aatatcatca gctagctctt ctcttccagc taatagcgct
     2101 ccaaccatca aaggaacctc catcaacaga tctcctctat gatagttctt actctcataa
     2161 aaagcctctg ccatcgtaaa atcagacttt aacacataaa gagctaagat ttcatacctt
     2221 gtccctaagt gatctccttc atcgtattga tgaatttcta agaggtggtg taaagccttt
     2281 tcataaagac cattttgctt gtacagcatg gccagctcaa atttttgaga caagtaaggt
     2341 ctctcttcaa gattcaccca tcccataggc ttagaagcaa gccaggcctg atgctgacag
     2401 tcttcatcaa aggccaaata cttgattaaa tcataggctc tatctcctgc aaagtgctcc
     2461 aagtccgaca acgactggtt atccatactg tttaaaagag cctctaagtc atcactgaaa
     2521 aactctgtct catgcccaaa gagcgtatca tcttctgcat cagcttggcg atagtgctgt
     2581 aagctaacaa ccttatctct atctttttta tctttttctg tcataatgcc ctttcactct
     2641 attggccatt tatactctta ttttaccatt tttgttataa tgagggtatg aaaatcagtc
     2701 aaatcgaaaa gaaaaaacac ttatacctca ttaagctaga caacggtgat aacctaacgg
     2761 tcacagaaga tacgattatc agatttatgc taagtaaaca catggtcata gatagccaac
     2821 aatgggagga catcaaaagc ttcgcacaat tttcatatgg taaaagcaag gccttaggct
     2881 ttattgcctt ccaacaaagg agccaaaagc aggtccaaga ttatctgcta aagcaccaga
     2941 ttagtcctga tctcattcca agcattattg atagcctaaa acaaggcaag tggattgatg
     3001 accagcaata cgttgacacc tatgtacgcc aaaatagcct cactggtgac aagggaccat
     3061 tgcttctcaa gcaaaagcta atgctaaagg gaatagcctc acaactcatc gagcctgttc
     3121 tggcacagac tgatttttct tctatagcgc aaaaggctgc ggaaaaaatc taccagaaat
     3181 accaaccaaa attaccaagt aaggccttga ccgataaaat catagaagga cttcttaaca
     3241 agggcttttc ctatgacctt accaaaggca ttgtcagtca actaagcctt gagcaggata
     3301 gtcagcatat caaagacctg cttgatcagg aattcgacaa attgtttcga aaatatagtc
     3361 gccgctatga tggctatcaa ttgaagcaaa agctttacca agccctttac cgcaagggct
     3421 atgacagtga tgatattaac actaagctaa atgattattt ctagtcctat caaggctgct
     3481 gcaccgattt gacgcaaaag cttttagtca gcaacaaagt agtcctatta caatcctgtc
     3541 gctttgataa tgctttagct agctcttcaa ctgaacatca gatttctcaa agcttcttta
     3601 ggtatttgtc agatcatatt gtccaaaaca gtgatttatt ttctcaatta tggtaaacta
     3661 tagaggataa gtttaattgt agaaagttgg taaggcatga aattacctaa agaaggcgac
     3721 tttattacaa ttcaaagtta taagcatgat ggtagattgc accggacctg gcgcgatact
     3781 atggtactaa aaacaactga aaatgctctg attggagtta atgatcacac acttgttact
     3841 gaaagcgacg gcaggcgatg ggtgacacga gagcctgcga ttgtttattt tcataaaaaa
     3901 tactggttca atattatagc aatgattcga gataatggtg tttcttatta ttgcaaccta
     3961 gcaagtccat acctgatgga cgcagaagca ctcaagtata ttgactacga tcttgatgtc
     4021 aaagtctttg cagacggtga aaagagattg cttgatgttg acgaatatga aatgcacaag
     4081 caagaaatgc attattcacc taatttggat tttattttaa aagagaatgt caagctatta
     4141 gtcgactgga tcaataaaga aaaaggacca ttttcaaaag cctatgtcag tatttggtac
     4201 aaacgttatc ttgaactgaa gaatcgttag tcgttgtcta gcactccaca gggagtgctt
     4261 tatttaatag ctagtataac atcatattag taagtcgatc tggagcttac aacctgtcag
     4321 catttgttat caaatgcata tcattaacca ctgtagcttg gcacaagcac agacagccta
     4381 taacaccaag tagcaatcaa cagttatcat cagctaccta gctagatcag gcattcggat
     4441 gacctcatca taaaatcgca acaatagaaa ggattgacaa tggcatttca aacaacaaaa
     4501 ggacgatacg caagctttgg cgttgcagtc agccttccac ctgagctcat tgataccttc
     4561 tgggaaatca ttgaccatta cctaaaagga gtgtttcccc tcaatactgt tctcaccttc
     4621 aggctaatta aaaataaaaa aaacctttct tatgagtaca ttgatcaaca agctgggctt
     4681 cggattgttt ttgactataa cacaccattt aacgcctttt accccaaaac gctctatatc
     4741 gtagaccagc aaggaattga aacgatttta ttgcctcacg agatgtattg ataagacctc
     4801 agacatcagc tgtaagatcc ttaccattca gttgtagctc atcacatccg ctacaagcac
     4861 caacatgaga taatcttgtg tctttatcct agctctgaat gctgtataga tattaagcca
     4921 gccaaataca tagcaataaa ctaagcccat gccggtagaa atagtgctaa catgaactta
     4981 aaaaattttt cattctgtga atcattgcta agcaaataca tcacctaagc cctatttcct
     5041 attctgggaa atcttgatag aacatcccaa tagtcccatc atattgagct atatctatag
     5101 ggtccgacat tttgatatgt tatcatctca ttttacgaca atcactatag gctttatgac
     5161 aattggcatc attgtcataa cgattaaatt ctatatgacc aaatggctag taggaagcta
     5221 attgctttgc gttagcctca cataggatcc tcacataccc cgtaatctta aaagtagttt
     5281 taactgcaca aaacttatag aacctaaaaa tcaacaaaca cactttaaag tacaaaaact
     5341 ttgccctccc tcaaaaagct ctataatctc tgtagtcggt aagcccactg tggaaattat
     5401 agttttttta attgtacaaa aacaagccca tatgacttat catgaaacgc aatcaaacca
     5461 tcattagaaa gactcatagg aacaccttaa gcattactca gcatttaaaa aacaatatcc
     5521 aaccgttgac tgttctaaaa gctcaccccc acatcgttat caatcctaag cttgattatt
     5581 cagttctctt atgccctcac tacaaaggaa acatgagcaa acaagacttc caaaaagcct
     5641 ctaaaatccc tatcttcgat tgccaaagct ttccaacact gcttcaactc aaaaaacact
     5701 gctttcagtg gaaagccagt tctaaa
//
LOCUS       DARYSY010000079         5718 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYSY010000079 DARYSY010000000
VERSION     DARYSY010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5718
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            101..415
                     /locus_tag="TVR04_001801"
     CDS             101..415
                     /locus_tag="TVR04_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270467.1"
                     /translation="MKPQYRKGGYSNKKAKQYVDLQEPIYLFGDELEPQQKFEDGKPT
                     GEIIAYKTWFGQKGLPPFQVKFLEKPNLPEYLSLVTFDNLQACEINYNVYFKADGLKE
                     VK"
     gene            415..1503
                     /locus_tag="TVR04_001802"
     CDS             415..1503
                     /locus_tag="TVR04_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013991316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEL1270468.1"
                     /translation="MVQSLAKRELEQYLLQSLNMALGSVLQGETSYTNSFNISVQEDG
                     FIFIPRLPSGFIIDDDLYQKIFLIANASLYPQYTLLKQNSAYFIALKTDDIHVQRGLF
                     FPWKKGISERLVISDLEQFSTSLKGNSIPIMKNLVINYDKVTSLAIAGNSGSGKSYAL
                     TYLLSVLQNISDLIIVDPKFDTPSRWARQHQIAVIHPQENRSKSDFVSEINESLSQCL
                     AIIHKRQGILFENPRHEFKHLTIVIDEVLALSEGVNKNIKDSFFSLLSQIALLGRATK
                     VHLLLVSQRFDHNTIPVSVREQLNVLIQIGNINQKTTQFLFPDLNPEGIVIPIGKGTG
                     LIQIIDNEHPYQVLPLLCPTYYTKKGIL"
     gene            1507..2106
                     /locus_tag="TVR04_001803"
     CDS             1507..2106
                     /locus_tag="TVR04_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270469.1"
                     /translation="MKKSYYQKIFNPCIVLFFTGFLSIICSFLLNIGMNSLQRIAYLA
                     FLYQFVSTLYTTNLLIAIISLFLFLALVYYEVFLRLKEDSLSNLWKSVYQTFTMRIFL
                     KQSEHSETVTTIEQAKVTRYNPINKYFNRAVRKAIVDVRENKVTLLIRIPKTQQATKI
                     LKDMEMLISEEIANRNHDYYFSRPERNGKWLYFVGTKRK"
     gene            2320..2925
                     /locus_tag="TVR04_001804"
     CDS             2320..2925
                     /locus_tag="TVR04_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEL1270470.1"
                     /translation="MAKEQRSNKWAFLFYKESAPDNYLEILEEIHVPFVLSPWHDKDI
                     NKETGEFKKAHKHGAFYFDSLKSYSQVSELIKDKLNGPAHVEPVMSPKGMYDYFTHAE
                     NPDKTPYNIKDIESGCGFNLDQFLVEQNSENFMTEVIDTIETNDFTEFEELVWYARDN
                     NTALLGLIIERTFFFARYLDSRRHNPKRHQQNKDTEVENDE"
     gene            2918..3097
                     /locus_tag="TVR04_001805"
     CDS             2918..3097
                     /locus_tag="TVR04_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270471.1"
                     /translation="MNDTPLLLTRQQASDFLGIDPKSFDRYIRKHPDFQCFMVGKQER
                     YLKTYLITFIENHCV"
     gene            3187..4233
                     /locus_tag="TVR04_001806"
     CDS             3187..4233
                     /locus_tag="TVR04_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1270472.1"
                     /translation="MATITKRGNSFRATVSLYKKGEYKRETKTFSNKKDAQLWTLEME
                     LEKGRGKNIAERSTQFTDFYRNWVHTVKKNDVREATFINYKRTLVVIDSLFDGIQLKH
                     LDDLIMQKKIDQYAENHSKKTVKELVLKIRGSLKYAYARGLISNDFGHLLKAKGLELS
                     KRNIPLSITEFKQLKQYCLSHTEDEFNILVALALETGARRGELLGIKKEDIFEYGVKI
                     SRSISPTNDDTQLKTKYSKRDISINKDVYQAIVELASKKEDYIFDWNGFRQAQQLQKL
                     LKKLGLTKTTFHGLRDTHASFLFSKDISLDYISRRLGHNSILTTQQYYLELMPEKKHQ
                     QDADALSLLNDLSS"
     gene            complement(4290..4682)
                     /gene="rpsI"
                     /locus_tag="TVR04_001807"
     CDS             complement(4290..4682)
                     /gene="rpsI"
                     /locus_tag="TVR04_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1270473.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(4702..5148)
                     /gene="rplM"
                     /locus_tag="TVR04_001808"
     CDS             complement(4702..5148)
                     /gene="rplM"
                     /locus_tag="TVR04_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1270474.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
BASE COUNT         1897 a         1149 c          976 g         1696 t
ORIGIN      
        1 aaaggaaaaa tttatcaagt ccagctcatg acctcaaacc gagcatgtcg actacactac
       61 aaaatgaaaa atagaataca agaggtattt caaaatgaaa atgaaaccac aataccgcaa
      121 aggcggttac tcaaacaaaa aagcaaaaca atatgttgac cttcaagaac caatctactt
      181 gtttggtgac gaacttgaac cccaacaaaa gttcgaagat ggaaaaccaa ctggcgaaat
      241 tatcgcctac aaaacatggt ttggtcaaaa agggctacca ccatttcagg tgaaattcct
      301 tgaaaaacct aaccttcctg aatatctttc tcttgttact tttgataact tacaagcctg
      361 tgaaatcaac tacaatgttt actttaaagc cgatggattg aaagaggtga aataatggtt
      421 caatctcttg caaaaagaga attggaacaa tacctgttac agagtctaaa tatggcttta
      481 ggctctgttt tacagggtga aacatcatat accaattctt ttaatatttc tgttcaagaa
      541 gatggtttta tcttcattcc acgtcttcca tctggcttta ttattgatga cgacttgtat
      601 caaaagattt tcctaatcgc caatgcgtca ctctacccac agtacacact gttaaagcaa
      661 aattccgctt actttatcgc attaaaaaca gatgatattc atgttcaacg agggctattc
      721 tttccatgga agaagggcat ttctgaacgt ctggttattt ccgaccttga acaattttcc
      781 acatctctaa aaggtaatag tattcccatc atgaaaaatc tcgttattaa ctatgataaa
      841 gtaacttcgc ttgctattgc tggtaattcc ggttctggga agtcctatgc tcttacatat
      901 ttattgagcg tattacaaaa catctctgac ctgattatcg ttgatcccaa attcgatact
      961 ccttcacgtt gggcaaggca acatcaaatt gctgttattc accctcaaga aaaccgttcg
     1021 aagtctgatt ttgtgtcaga aattaacgaa agtttaagtc aatgcttggc tattattcat
     1081 aaacgtcaag ggattctctt tgaaaatcca cgtcatgagt ttaaacatct aactattgtt
     1141 attgatgaag tacttgcctt atcagaaggt gtcaataaaa acatcaagga ttccttcttc
     1201 tccttactct ctcaaattgc attactagga cgggcaacaa aggttcattt actccttgtg
     1261 agccaacgct ttgaccacaa tactatacct gtatccgtac gggaacaact taacgtactc
     1321 attcagattg gaaacatcaa tcagaaaact acgcagtttt tgttcccaga ccttaaccca
     1381 gagggcattg ttattccaat tggaaagggg acagggctta tccaaattat tgacaatgaa
     1441 cacccgtatc aggttttacc cctactttgt cctacatatt acacaaagaa aggtattctg
     1501 taaccaatga aaaaatcgta ttatcaaaaa atctttaatc cgtgtattgt cctatttttt
     1561 accggatttc tcagtatcat ttgttcattc ttgctcaata tcggtatgaa ctccttacaa
     1621 agaatcgcct atctagcctt cctttatcaa tttgtaagta cgctctatac tactaacttg
     1681 cttattgcta ttatctcact cttccttttt ctagcactgg tttattatga agtgttctta
     1741 cgattaaaag aagatagtct atcaaaccta tggaaatccg tttatcagac atttactatg
     1801 cgtatctttt taaaacaaag tgaacactct gaaactgtaa caactataga gcaagcaaaa
     1861 gtaacacgct acaaccccat taataaatat tttaaccgag cagttcgaaa agcaattgta
     1921 gacgttcgag agaataaagt tacactgttg attcgtattc ctaaaactca acaagcaaca
     1981 aaaattctaa aagatatgga aatgcttatt agtgaagaaa ttgccaaccg taaccatgac
     2041 tattactttt caagacctga gcgaaacggc aaatggttat actttgtcgg tactaaacga
     2101 aaatagctaa aaggaacggc gctgtggctc acgtagtgaa agccaaacag cgccgttttt
     2161 agagtaaaat attggattaa gtgggggtac tacgaccccc acttaatcca ataatcaata
     2221 atcaaaaaaa tcaagatttt tctcaaaaaa ctccgatttg tactttccca atctcctaat
     2281 agatagaaat aaaaaaattg aaagcgagga attttgccta tggcaaaaga acaacgttcc
     2341 aataagtggg ctttcttatt ctataaggaa agtgcaccag acaactattt agagattctg
     2401 gaagagattc acgttccctt tgtactctcc ccttggcacg ataaggatat aaacaaagag
     2461 actggagaat ttaagaaagc tcataaacat ggtgcattct attttgattc tcttaagagt
     2521 tattctcaag tttcagaact tatcaaagac aaattaaacg gtcctgccca tgtcgaacct
     2581 gtcatgtctc ccaaaggaat gtatgattat ttcactcatg cggagaatcc agataaaaca
     2641 ccgtataata tcaaagatat tgagagtggg tgtggcttca atcttgacca atttttagta
     2701 gaacaaaact cagaaaattt catgacagaa gttatcgata ctattgaaac aaacgacttc
     2761 accgagtttg aggaacttgt ctggtatgct cgtgataata acactgcctt attgggacta
     2821 atcattgaac gaactttctt tttcgctcgc tatttagatt ctcgccgaca taatccaaaa
     2881 cgacatcaac aaaacaaaga cacggaggtt gaaaatgatg aatgatacac cattactatt
     2941 aacaagacaa caggcttctg attttctggg aatagaccca aaatcctttg atagatatat
     3001 taggaaacac cctgattttc aatgttttat ggttggtaaa caagaacgtt acttgaaaac
     3061 ctatttaatc acatttattg aaaatcactg cgtataacca tcaacaattg ataaaatccg
     3121 atttttcata tatcctatat gtgactagtc tattttatca atcattttta tagagaggct
     3181 gataaaatgg caacaataac aaaacgtgga aattctttcc gtgcaactgt gtcactatac
     3241 aagaaaggag aatataaacg agaaaccaaa acattcagca ataaaaaaga tgctcaactc
     3301 tggacgttag aaatggaact tgagaaagga cgtggcaaga atattgctga acgctctacc
     3361 caatttaccg atttttatcg aaattgggtt catacggtta agaaaaatga tgtccgtgaa
     3421 gctaccttta tcaactataa acgaacactc gtagtaattg atagtctttt cgatggtatt
     3481 caacttaaac atcttgatga cctcatcatg caaaagaaaa ttgaccaata tgcagaaaac
     3541 cattctaaaa agacggtcaa agaacttgtc cttaaaatcc gtggctcgct gaaatacgct
     3601 tatgctcgtg gtttgattag caatgacttt ggtcatctac taaaagcaaa agggttagaa
     3661 ctatcaaaac gtaatatccc actctccatt actgaattca agcagctcaa gcaatattgc
     3721 ctaagccata cagaagatga atttaatatt cttgtcgcct tggcacttga aaccggtgca
     3781 agacgtgggg aacttcttgg tatcaagaaa gaagatatct ttgaatacgg agtaaaaatt
     3841 agtcgttcaa ttagccctac taatgatgac actcagttaa aaactaaata ttctaagcgg
     3901 gatatttcta ttaacaaaga cgtttatcaa gctattgtag aacttgccag taaaaaagag
     3961 gactacatct ttgattggaa tggctttaga caagctcaac aactgcaaaa attgcttaaa
     4021 aaacttggat taactaagac aacttttcac ggtctacgtg acacccacgc ttcatttctt
     4081 ttctcaaaag atattagctt agattatatt tctcgccgtt taggtcacaa ctcaatccta
     4141 acaacacaac agtattatct tgaattgatg ccagaaaaaa agcaccagca agatgccgat
     4201 gctttaagtc tcttaaacga cttatcatca taattaacac caactgacac caaaaaatgg
     4261 ctgtaaacgc tggtataata aggttttgat taacgttttg agaactggct agctttacga
     4321 gctttcttaa gacctggttt tttacgttca accatacgtg cgtcacgtgt tagaagacca
     4381 gcgcgtttta atgagtcgcg gaagtctggg tccacttgaa gaagcgcacg agcgatacca
     4441 tgacgaatcg cacctgattg accagcataa ccaccaccta caacgttaac aaaaacgtcg
     4501 tatgagcctt cagttgaagt cactgcaaaa ggctgattaa tgatcaaacg taagtcagca
     4561 tgtgggatgt attcttcaac atctttttta ttaacagtga ttttaccagt acctggaact
     4621 aaacgaacgc gtgcaacagc gtttttacga cgaccagtac ctgcatattg tgcttgtgcc
     4681 attatttaat gctcctttct cttagataag tcctgaaata tcaagtactt ctggttgttg
     4741 tgcagcatga gtgtgctcac caccaacaaa gacctttaat ttcatacctt gtgcacgtcc
     4801 aagagtgttg tgtggaagca tgccttttac tgacttttca atcaaacgaa cggcattttt
     4861 agagcgaagc tcaccagcag tgattgattt caagccacct gggtacattg agtgagtgta
     4921 ataaacctta tcagttgctt ttttaccagt taatttaacc ttctcagcat tgataacaat
     4981 aacaaagtca cctgtatcag tgtgcggtgt gaaggttggc ttgttctttc cgcgaagtac
     5041 gctagcaact actgcagaaa ggcgtccaag tggcacatct gttgcgtcaa caacgtacca
     5101 tttacgttca acttggcctg gtttagccat gaaagttgtt ttgttcatga tttctcctat
     5161 acgaattcgt ttttgtttac attagtgatg gatgttccgg tccatcgaag gtatttggaa
     5221 ggttccgggg cctttcaaat ggggtaaaca ataccgtcta ctatagtatc aaacttctta
     5281 actgatagtc aagtggttta gctctatttc tttgattatt tttgcttttt cacaagaaga
     5341 acaggcttgc ttttgagctg gactattagc cttgacttcc ctccaaaaaa tccgctcagt
     5401 tcctgttagc tcctatgcaa ataacaatac aaagattagt ggtggaatga ccaaagctcc
     5461 tgtcaactgc taaaacattt gacatctgac ttctggcaaa tcaaaaagcc ctgttctgtt
     5521 atgctagttc cttgcctgca cgcgcacctt cattgtcaaa caattcattc tgacttttga
     5581 ttaaaaataa aaaacgcgaa cacccatact cttaagcggc gtcacagcta aaacaaacta
     5641 tagcagacaa aaaagaattg aaacaagctg atatactccc cttatagtgg acagtgaaaa
     5701 aacaaaaatt cactagaa
//
LOCUS       DARYSY010000080         5429 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYSY010000080 DARYSY010000000
VERSION     DARYSY010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5429
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            34..813
                     /locus_tag="TVR04_001809"
     CDS             34..813
                     /locus_tag="TVR04_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1270475.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKDGRVFIYFTVEEIMRRRNISKPTAIKTLDELDMKKGIGLIERVR
                     LGLGKPNVIYVKDFMSILAVKENDFQKSKNLTSEVKDFNLRSKENELQEVQNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLTAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            810..1661
                     /locus_tag="TVR04_001810"
     CDS             810..1661
                     /locus_tag="TVR04_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1270476.1"
                     /translation="MMKELEKVMIEDVEYSYDPEKEYIKDGHAFCKVCHERKDGKVME
                     FFDNKMIFKISCKCDRDREEREKERQKQMEIERLKSSCFNSIIQWSYTFENYQGEENQ
                     SLIIAKNFVKDYEEMKKENIGLLFYGSVGSGKTYLACSIANSLIEQYQIGVKIRNFAQ
                     IINELQKGGFDFDKNAYIESLVNTSVLILDDLGIERDTSYAKEQVYNIVNNRYLKQKP
                     TIFTTNLSYDTIQNCKDSVEYQRIYSRIIEMCIPVMVVGEDFRKVIQKDKLNRNKDRL
                     LNGGERS"
     gene            1658..2143
                     /locus_tag="TVR04_001811"
     CDS             1658..2143
                     /locus_tag="TVR04_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1270477.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNTNGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKERGKYSVF
                     FQAKDMKVMDKAFKHALSESEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            2140..3921
                     /locus_tag="TVR04_001812"
     CDS             2140..3921
                     /locus_tag="TVR04_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEL1270478.1"
                     /translation="MIDKILKDIKGLFKVQDKVKFLKQNIPYLAFFYIGNIFSHHVRA
                     YIGGDIIDKIFQGILEINTMSFLPSLHPTDIIMGVVVAVLIKIIVYTKGKNVKKFRQG
                     KEYGSARWGNKKDIEPYMDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKSGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDDETYMNPIDRLFEALEKREPTHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIRELRDLMSEDELELDTLGDRKTALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDNADTIVGNCDSTLFLGGKEKTTLKELSETLGKETIDLYNTSETRSNQK
                     SFGLNYQKTGKELMSQDEITVMDGGKCIFQLRGVRPFLSDKFDITKHKNYKFLEDYDK
                     KNVFDIEEYIKRKGKVKLNRNTVITRL"
     gene            4003..>5429
                     /locus_tag="TVR04_001813"
     CDS             4003..>5429
                     /locus_tag="TVR04_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HEL1270479.1"
                     /translation="MSTIKIENLTFSYYGYVKPIFENVSFSFDTNWKTGLIGRNGIGK
                     STLFKLLLNQEVYKGKISKSVDFIKFPPNISDTSKLGIELYEELISDEEEWKLFRELN
                     LLNVDENLVYREFETLSKGEQTKILLAILFTKQDGFLLIDEPTNHLDMDGRKIVSEYL
                     KSKKGFLLISHDRDFLDGCINHVISINRNSIDVQSGNFTSWYENKVMKDRFEISQNEK
                     LRKDIKRLKEAARQSKIWSDKIENTKNGVKVSGVKPDKGHIGHQSAKMMKKSKNLENR
                     QNKAIEEKQSLLKDIETKESLLLHPLHHHKSPLISVSNLSSCYGERQILSNVSFEIKQ
                     ADIVAIYGQNGSGKSTLIKILLGLHHEYIGEIKSASNLKISYIPQDTSNLTGSLNEYI
                     HKQGVDETLCKTILRKLDFARELFEMDMKNYSDGQKKKVLIAASLSKPAHLFVWDEPL
                     NYIDVISRIQIEEIIKEAKPTLIFV"
BASE COUNT         2131 a          728 c         1090 g         1480 t
ORIGIN      
        1 ctttgtaaaa ttttaaggaa aggaggtgaa gcgatggact ttgactattt ctataacaga
       61 gaagcggaaa gatttaactt tctaaaagta ccggagatat tggtagacgg agaagaattt
      121 aagggattat ccgctgaagc gattatcctt tattcaatgc ttcttaaacg gacaggaatg
      181 tcttttaaga ataactggat agacaaagat ggcagggtat ttatctattt tactgttgaa
      241 gaaattatga gaagaagaaa tatctcaaag ccgacagcta taaaaacatt agatgaactc
      301 gatatgaaga aaggaatcgg actgattgaa agagtaaggc ttgggcttgg taagccgaat
      361 gtcatatatg ttaaagactt tatgagcata ttagcggtaa aagaaaatga ctttcagaag
      421 tcaaaaaact taacttcaga agtaaaagat tttaacctca gaagtaaaga aaatgaactt
      481 caggaagttc aaaatcttga ctctaactat atagagaata ataagagtaa gtatagtaag
      541 agagaatata gttttggtga aaacgggctt ggaacatttc aaaatgtatt tttaacggca
      601 gaagatatat ccgatttaca aatcataatg aactcacagc ttgataatta cattgagaga
      661 ttatctgcat atatcaaaag caccggaaag acctataaag accataaagc gacaatcctt
      721 tcttggtttt ataaagatca ggggagagga aaagaagtga aaacatcaaa tatcccgaca
      781 tgggaagaat atgataaagg agaacaccta tgatgaaaga attagaaaaa gtaatgatag
      841 aagatgtaga gtattcttac gatcctgaaa aagaatatat caaggatgga cacgcatttt
      901 gtaaagtttg ccatgaaaga aaagacggaa aagtgatgga gttctttgat aacaagatga
      961 tatttaagat ttcttgcaaa tgcgatagag atagagagga aagagaaaaa gaaagacaaa
     1021 agcagatgga gattgaacga ttaaagagta gctgctttaa ctcgattatt cagtggtcat
     1081 acacatttga aaattatcag ggagaagaaa atcaaagcct tatcattgca aagaactttg
     1141 taaaagacta tgaggaaatg aaaaaagaaa atatcggact tcttttttat ggctcagtag
     1201 gtagcggaaa gacctatctt gcctgctcca ttgcaaatag ccttattgaa cagtatcaaa
     1261 taggcgttaa aataagaaat tttgcacaga ttatcaatga actgcaaaag ggaggatttg
     1321 attttgacaa gaacgcatat attgaatccc ttgtaaatac ttccgttctt atcttggatg
     1381 acttaggaat agaaagagat acaagctatg ctaaagagca agtatataac atcgtgaata
     1441 acaggtactt aaaacagaaa ccgactatct tcactactaa cctttcctac gacacaatcc
     1501 aaaattgtaa ggatagcgta gagtatcaaa gaatctactc aagaatcata gagatgtgta
     1561 ttcctgttat ggttgtagga gaagatttta gaaaggttat tcaaaaggac aaactgaatc
     1621 ggaataagga cagactgctg aatggaggtg agagaagttg atcaatgaag aaatagcaag
     1681 aaaaacactg aatatggaag ttagagctgc taaagtaaca ggaaagctaa ttctgaactt
     1741 gttaaagaaa ttgatgaaag aagcagaaaa acttggagga cttgaaaagc tggttaatac
     1801 taacggaaat gaagtaaagc taaaagatat ggttaaaaag gggcagcttg aagaaattcc
     1861 agttgaagaa gcagaactta aggaactcaa aaaggaactt aatcggtatg gggtaaagtt
     1921 ttcagtcatg aaagataagg aaagagggaa atactcagta ttctttcaag ctaaagatat
     1981 gaaggttatg gacaaagcat ttaagcatgc cctttcagaa tcagaaaaga aaacggaaag
     2041 gaaggagtcc attcataaga atattgagaa gtttaaggag atggctaaaa actctgtttc
     2101 caaagataaa atcaagaata aacaaaagga gcagagccta tgatagataa aatattaaag
     2161 gacatcaaag gcttatttaa ggtgcaagat aaggtaaagt ttctaaagca aaacattccc
     2221 tatcttgcat ttttctatat aggtaatatc ttttcacatc atgtaagagc ctatataggt
     2281 ggcgatatta ttgacaaaat ttttcaaggg atattagaga ttaatacgat gagctttctt
     2341 ccaagccttc atcctacgga tattataatg ggcgtggtag tagctgtttt aatcaaaatt
     2401 atcgtatata ccaaagggaa aaatgttaaa aagtttagac aggggaaaga gtatggctca
     2461 gcaagatggg gaaataagaa agatattgag ccatacatgg atgaaaagtt tcaaaacaat
     2521 atcttgctta cgcaaacaga acgcctaact atgaatggta gaccagctaa tcctaaatat
     2581 gctcgtaaca aaaatgtgct tgtaatcggt ggatcaggaa gtgggaaaac gagattttat
     2641 gtaaaaccga atcttatgca gatgcactcg tcatattgtg taaccgatcc taaaggaact
     2701 atagtccttg agtgcggtaa gatgcttgaa gataacggat atgagataaa aatcctaaat
     2761 accattaact tcaaaaagtc tatgaaatac aatccctttg cttatcttag aagtgaaaaa
     2821 gacatactaa aattagtaca gacaatcatc gcaaacacca agggagaggg agaaaaatca
     2881 ggtgaggatt tttgggtaaa agccgaaaaa ctctactaca cagcacttat cggctacatc
     2941 ttctatgaag ctccaagaga agaaaagaac tttgcgactc tactcgatat gatagatgct
     3001 tctgaagtca gagaagatga tgaaacctat atgaatccca tagatagact ctttgaagca
     3061 cttgaaaaaa gagagccgac acactttgca gtgaagcaat ataaaaagta caaattggct
     3121 gccggaaaaa cggcaaaatc tattcttatc tcttgtggtg caaggcttgc tccatttgat
     3181 attagggaac ttagggactt gatgagtgaa gatgaacttg agcttgatac actcggagat
     3241 agaaaaacgg cactctttgt tattatctct gatactgatg atacctttaa ctttgtagta
     3301 tccattatgt actcacaact ttttaatctc ttatgtgata aggcggatga tgtatatggc
     3361 ggacgattac ctgtccatgt gagatgcttg cttgatgaat ttgcaaacat cggcttaatt
     3421 ccaaagtttg agaaacttat agcaacaatc cgttccagag aaatatcagc aagtatcata
     3481 cttcaagcac aatctcagtt aaaggcaatc tataaggata atgccgatac aatcgtaggt
     3541 aactgtgata gtaccttgtt ccttggtggc aaggagaaaa ctacactaaa agaattgtct
     3601 gaaacactgg gaaaagaaac gatagattta tataacacat cggaaacaag gtcaaatcaa
     3661 aagtctttcg gacttaatta tcaaaagaca ggtaaggaac tgatgagcca agatgagatt
     3721 actgtaatgg acggtggtaa atgtattttt cagcttagag gtgtaagacc ttttctttca
     3781 gataaattcg acatcacaaa gcataagaac tataagttct tagaagatta tgacaagaag
     3841 aatgtgtttg atattgaaga atatataaag agaaaaggca aggttaagct taatagaaat
     3901 acggtaatta caagattgta agatttactg ttataactat atggtcgagg gtatatttga
     3961 tataatagag ctagataaat ttgaatttga gggggtgttt ttgtgtcaac aattaaaatt
     4021 gaaaacctca ctttctcata ttatggctat gtaaaaccta tatttgaaaa tgtatcattt
     4081 tcatttgata cgaactggaa aacagggcta ataggaagaa acggaattgg aaaatcaaca
     4141 ctattcaagc tacttctaaa ccaagaagtt tataagggga aaatcagcaa aagtgttgac
     4201 tttattaaat tcccacccaa tataagcgat acttcaaaat taggaattga gttatatgaa
     4261 gaactaatat cagatgagga agaatggaaa ctatttagag aacttaactt gctaaatgta
     4321 gatgagaatc ttgtttacag agagtttgaa acactttcta aaggagaaca aacaaaaatc
     4381 cttttagcta ttttgtttac aaaacaagat ggttttttac ttattgatga accaacaaac
     4441 catttagata tggacggaag aaaaattgta agtgaatatc ttaaaagtaa aaaaggtttt
     4501 ttgctcatat ctcatgatag agatttttta gatggctgta tcaatcatgt aatttctatt
     4561 aacaggaatt ctattgatgt tcaatcagga aattttacat catggtatga aaacaaagtg
     4621 atgaaagacc gatttgaaat cagtcaaaat gagaaattaa gaaaggatat taaacgatta
     4681 aaagaagctg caagacaaag taaaatttgg tcagataaaa ttgaaaatac taaaaatggc
     4741 gtgaaagtat ctggtgtaaa accggataaa ggacatattg ggcatcaatc tgccaagatg
     4801 atgaagaaat ccaagaattt ggagaataga caaaacaagg caatagaaga aaaacagagt
     4861 ttgctaaaag atattgaaac aaaggaaagt ctattattgc atccattaca tcatcataaa
     4921 agtcctctaa tatcggttag caatttatca tcatgctatg gagaaagaca gatattaagc
     4981 aatgtaagtt tcgagataaa acaagccgat atagtggcta tatatggtca aaatggtagt
     5041 ggaaaatcaa ctttgattaa aattttgtta gggttacatc atgagtatat tggtgaaata
     5101 aaatcggcaa gtaatttaaa aatatcgtat attcctcaag atacatctaa tttaacaggt
     5161 agcctaaatg agtatattca taagcaaggt gttgatgaaa cattgtgtaa aacaattctt
     5221 aggaaattag attttgcaag agaattattt gaaatggata tgaagaacta tagcgatgga
     5281 caaaaaaaga aagttttaat cgctgcaagt ttgtcaaaac cagctcattt atttgtttgg
     5341 gacgaaccgc taaattatat agatgtaata tcgagaatac agattgagga aattataaaa
     5401 gaagcaaaac ctacactcat atttgtgga
//
LOCUS       DARYSY010000081         5410 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYSY010000081 DARYSY010000000
VERSION     DARYSY010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(104..844)
                     /locus_tag="TVR04_001814"
     CDS             complement(104..844)
                     /locus_tag="TVR04_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1270480.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(844..3009)
                     /locus_tag="TVR04_001815"
     CDS             complement(844..3009)
                     /locus_tag="TVR04_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1270481.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKASPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGAYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQMDSGEYVGIDMDLIRAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            3201..5192
                     /gene="uvrB"
                     /locus_tag="TVR04_001816"
     CDS             3201..5192
                     /gene="uvrB"
                     /locus_tag="TVR04_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1270482.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIEALVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
BASE COUNT         1562 a         1109 c         1201 g         1538 t
ORIGIN      
        1 tagtgaattt ttgttttttc actgtccact ataaggggag tatatcagat gcttaccttt
       61 gctttttaat tatttttcgg cctttagtag agtatcttgc cgcttaaaca tttaagacct
      121 tatctaaaaa ttcaattaag cgtggatgct tagggtgatc aaagatttcc tctggagtac
      181 cgtcctctag gaattggccg ccgtctgtaa agatcacacg attagccact tgacgagcaa
      241 agcccatttc atgtgtcaca atcagcatgg tcatgccctg ctctgctagg tccttcataa
      301 cgtttaagac gtctccaacc atctcagggt caagagcaga ggtaggctca tcaaagagca
      361 tgatatcagg gttcatggca agacttcttg caattgcaac acgctgcttt tgaccacctg
      421 atagacttcc tgggaaagca tcagccttat cagctagacc gaccttctct agaagagcaa
      481 gtcccttttc cttggccgcc tcctttgaga cctttccaag ctcaactggt gcaaaggtaa
      541 tgttatcaag gaccgtcatg tgtggaaaaa ggttgaagtg ctgaaacacc atgccgatat
      601 tttcacgagc cttatcaata ttggtattag gatctgaaag ttcaaagcca tcaaccacaa
      661 ccttaccact agtaatggat tccaggagat tgagggtgcg caggaaggtt gattttccag
      721 agccagatgg cccaataata cagaccacat ctccttcgta aaacttggca ttaatgcctt
      781 ttaagacctc gttttgccca taggatttgt gtaaatcttg aacatcaatt tttaattctg
      841 ccattagtta agcctctttt ctaaacgttt tgcaagcctt gttaagagtg taatcataat
      901 caagtagata actgctagga tagcatacat gcggaaggat tgatagtttc tagcgataat
      961 gattttccct gtttggaaga gctccactaa accgatcgct gagactatgg tcgtatcctt
     1021 caaggaaatg acaaactgat tgatgaagtt tggcagcatt agcttaatgg cctgaggaag
     1081 gataatcctt cgcattgttg tgtgatatga caagcccaag ctgcgactag cctccatttg
     1141 acctgccggc acagcctcga tacccccacg aacaatttcg gcaatatagg ctccaccgtt
     1201 tagcgaaagt gcaatagtag cagctacaaa atcattaatc ggtgattggt ggccagtcat
     1261 gctttcaatg aggtttggca ctccccagaa gataaaggca gcaacaatca tcaaggggat
     1321 accacgcacc acatcaacaa agatagtgga agccatgcgc aggttctttg atggggatac
     1381 agccatcatt ccaaaaacaa taccaataac caaagcaatg gcaaaggaga tgagtgtcag
     1441 accaagggtt gttccaagcc cagccaataa ttgcttgtag ttattagcta aaagtccata
     1501 aatggttgac tcatcggctg ttttgacaga tgcctctgaa tcaaggtatc tgctaatgat
     1561 ggcgtcgtat tttcctgatg ctttaagagc agccaaaccg ttgttaaaca tttcgatgag
     1621 ctcagggttg gctccttttt taacagcaaa accatactca ccagaaggct cccctttgat
     1681 aggaatatca agcttgtggc ctcgctgaat agcgtacctt aaaatagctt catcatccat
     1741 aagcccgtca atagaaccag aatttaagct atcgtacatt gaggaggcct catcaaaggc
     1801 ttttagacgg taaccataaa tatccttgtt gctttcaagg aaatcatagg aggctgttcc
     1861 ttttttggca ccgactattt tacccttgag gtccttgtat gatttgatag agcttccgga
     1921 tttgacccca aggcgaatat ttgatgtgta gtaggaatct gaaaaatcaa aaatctcacg
     1981 acgtgcaggt gtgatagaca tacctgcaat aacagcgtca gcctgaccag cttgaacagc
     2041 atttaaagca gcgtcaaagc caggattgct gatttcaata gtaaagcctt gctgcttagc
     2101 aatagccctg atgaggtcca tatcaatacc gacatattcc ccgctatcca tttgaaattc
     2161 aaagggagca aaggaggagt cggccacgat tttataaacc ggctttaaag gagtggcctt
     2221 agcagaggca tcgccagtag ccttgcctgc tgtgaccttg tcattgctgc cgagccattt
     2281 tgtcatgata gcttgatagg ctccatcagc cttcatagcg cctaaggctt cattgaagtc
     2341 gtcaatgaga taatcatagc cgctgccttt tttgacagca aagccaaagc ttccaatagc
     2401 ctctcccttc atgttgatcg cgagatcctg cttttggtta atggcatatt gaatgacagg
     2461 ctcgtcgtcc ataacagcgt caatagagcc cgttgcaaga ctgttgtaca tcaggtcacc
     2521 tgtgtcaaat gttttaacag tataaccata cgattttttg tatttatcta agaaggcttg
     2581 agcagctgtt ccatttttaa caccgactgt ttttcctttt agctcgctat atttcttaat
     2641 agggctagcc tttcttgtag caataacaat ttttgtatcg taatagggat ctgaaaaatg
     2701 gaagaccttt tgacgagcag cagtgatggt ggtgcctgcc ataagggcgt cagcttgacc
     2761 ggactgaatg gcattgacag cagcatcaaa gccagggaat gtcatattga tattccaacc
     2821 ctttcgcttt gctacttcat tgatgatgtc aacatcaatc cccttataca cctgatctga
     2881 atccttgaat tcaaacggtg cataagcagt atcagaaaca atatcaattg tctctgcact
     2941 tgcaatccca gcagtcatca aaacaacaga cagcattgca agcatccatg cttttaatgt
     3001 gtttttcata ctagtctcct taataaaaat aaaaaatatg cctaattata gcagattttt
     3061 ttcaaacagg caaatcatct cttcttttta tgtcataaaa cctaacataa acaactaaaa
     3121 tagtcaaaaa gctttgatag ggtctttaag tccttaacta tgttacaata gataagagat
     3181 aagatattga ggactaatga atgattgata aacgtgattt taaagcattt aagctcgtgt
     3241 caaaatatgc cccctcagga gatcagccgc aggccattga agccttggtt gataatatcg
     3301 aaggtggtga aaaagcgcag attttactag gagcaacagg aacagggaaa acctatacca
     3361 tgagtcaggt gatcagcaag gtcaacaagc caacgttggt gattgctcat aacaaaacct
     3421 tggccggtca attgtacggt gagtttaaag agttctttcc tgaaaatgct gtcgagtact
     3481 ttgtatccta ctatgactat tatcagcctg aggcctatgt tccttctagt gatacctata
     3541 ttgaaaaaga cagctctgtt aatgatgaga ttgacaagct gcgccattcg gccacttcat
     3601 cgcttttaga gcgtaatgat gtgattgttg tggcttcggt ttcttgtatt tacggattgg
     3661 gctcaccaaa ggaatatgct gattcagctg ttagcctgcg tcctgggcag gagatatcca
     3721 gggatcagct gctcaatgcc cttgtagaca ttcagtttga acgcaatgac attgattttc
     3781 aacgtggacg ctttcgtgtg cgtggtgatg tggttgaagt atttccagcc tcaagagatg
     3841 agcatgcctt tcggattgag tttttcggtg atgagattga tcggattcgt gaaattgaaa
     3901 gcctaacggg taaagtatta ggtgatgctg atcatttagt gctttttccg gccactcact
     3961 ttgtgaccaa tgatgagcac atggagcagt ctattagcaa gattcaggca gaattagcag
     4021 accagcttaa gctatttgaa gcagaaggca aattgctaga ggctcagcgc ctgcgtcaaa
     4081 ggacagagta cgatattgaa atgctgcgtg aaatgggtta caccaatggt gttgaaaatt
     4141 attcccgtca tatggacggg cgttcggcag gagagccccc ttataccttg ttagatttct
     4201 ttccagagga ttttctcatc atgattgacg agagtcacat gaccatggga caaattaaag
     4261 gcatgtacaa tggagacaag gctagaaagc aaatgcttgt ggattatggc tttcgtcttc
     4321 catctgcctt agacaatcgt ccacttcgtc gggaggagtt tgaaagtcat gtgcaccaaa
     4381 ttgtctatgt ctcggcaacg cctggggatt acgagatgga gcagactgat acgattgtgg
     4441 agcagattat cagaccgaca ggtctgcttg atccggaggt tgaggtccgg ccaagcatgg
     4501 gacaaatgga cgacttgctt ggcgagatta acctgagggt tgaacgaggt gagcgcacct
     4561 ttatcacaac cttaaccaag aaaatggcgg aggatttgac cgactacctc aaggaaatgg
     4621 gtgtcaaggt aaaatacatg catagcgaca tcaagacatt agagcgtaca gaaattattc
     4681 gcgaccttcg tttaggcgtt tttgatgtct tgattggtat caatctgctg cgtgaaggta
     4741 ttgatgttcc ggaggttagc cttgttgcta ttcttgatgc ggataaagaa ggcttcctaa
     4801 gaaatgaacg aggtttgatt cagacgattg gtcgagctgc cagaaatgct gatggtcatg
     4861 tgattatgta tgctgatcgt atgacggatt ccatgcagcg cgctatagat gaaactgctc
     4921 gtcgtcgtgc catacagatg gcatataatg aagagcatgg gattattccg caaaccatta
     4981 aaaaagatat tcgtgattta atcagtattt ccagagcagt tgaagcaaaa gcaacagaag
     5041 cagagacaaa ttatgagtca atgacgcggt ctgaaagaca agaagctatt aagcaattgc
     5101 aaaaaaacat gcaggaagca gcagagctgc tggattttga attagcagca cagcttcgtg
     5161 acctgatcct agagttaaaa gcaatggatt aagacctgat aagctaagtc tggctgtata
     5221 agctaggctt tttatctgct tttgagtttg tcctttaggt ctgtcttatg atctttggta
     5281 ccagacaaat gagtgatacc ttgagcttga tctacgcaag agctattgca gctactaact
     5341 tcagactact ttaatgattt aatgaaagat tgattttgat aagacaattc tgatataatg
     5401 taaagtagtt
//
LOCUS       DARYSY010000082         5389 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYSY010000082 DARYSY010000000
VERSION     DARYSY010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5389
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            247..945
                     /locus_tag="TVR04_001817"
     CDS             247..945
                     /locus_tag="TVR04_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1270483.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHRWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            1165..3168
                     /gene="metG"
                     /locus_tag="TVR04_001818"
     CDS             1165..3168
                     /gene="metG"
                     /locus_tag="TVR04_001818"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1270484.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMMGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTDDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVKNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAMMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEINYIKEQMKMSTAKPQEADWDPEKVALKSEKDTITFEAFD
                     AIELCVAEIKEVSRVEGSEKLLRFRLDAGDGEDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGAIIG"
     gene            3726..4619
                     /locus_tag="TVR04_001819"
     CDS             3726..4619
                     /locus_tag="TVR04_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270485.1"
                     /translation="MGDIKIEIGKRIRTARLDKRFTQIDICDDESELTIRQLARIENG
                     QAMITLPKIIFLSEKLGIPVQDLIDEKIEIPKRYLELKNKLIKSHTYGDKERIRHHES
                     MFNEIYEEFYDNLPEEEQLLVEVLQVRLDVFSSRNSEFGISLLEEYFHQILKKKYHSY
                     NDLLIIDLYLFCCAVGLEDKTYFDDLSQKVLSYIDYSDFERIYVLEKILLSILIQVEP
                     EKYLLYTKVFREIMETTNNFQHKPAIYAFEAKYYLQVRKDVEKTIELYDKSIMFARML
                     NDSVLVSNLEKEKLEDLGNLT"
     gene            4972..5112
                     /locus_tag="TVR04_001820"
     CDS             4972..5112
                     /locus_tag="TVR04_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein"
                     /protein_id="HEL1270486.1"
                     /translation="MEQFKNLSQSELQNTNGGGAWSPIVTVPVPVVLPMKVVKWVAGF
                     FE"
     gene            5225..5383
                     /locus_tag="TVR04_001821"
     CDS             5225..5383
                     /locus_tag="TVR04_001821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270487.1"
                     /translation="MTRFETLDNMNFVSLSEAEMMEMTGGGFDIAAPIKAIFNAGKEF
                     GRALAKWI"
BASE COUNT         1615 a          891 c         1205 g         1678 t
ORIGIN      
        1 gagccgtact ttttggctaa tggttagtct tatggtgcta gttgatcctg caaagcatct
       61 tgataaaaga gactgcctat gctatactaa agctgtattt aggggactta ccgagtctag
      121 ctgcagaact tgctttggtg actatctgtg atcaagggca attgagctta gcttatcctc
      181 ctaataatca catcaaatac tgtttgtcag tatttttctt ttggaatcac attaaggaag
      241 gcaagtatgt caaagaggaa acgaaaaacg tatcaggtat atgagggctt aaggtgcgcc
      301 atgatgcttt gctttatcag tggttatgtc aatgccttta cctacatgac gcaaggcagg
      361 cgctttgcag gggttcagac aggcaatctc ttatcctttg cgattcgtct gtctgagcgc
      421 cagtttgacc aagccctgca atttttattg cctatcattg tttttatgat tgggcaggcc
      481 tttacctact ttatgcaccg ctgggccaat aagcatggtc tgcattggta ccttttgtct
      541 agctttatct tgaccctgat tgctcttgtg acagcaatcc tcacaccctt attgtcgtca
      601 ttttttacgg tttcagctct agcttttttt gcttcgattc aggtagatac ctttaaaacc
      661 ttgcgcggtg cgagctatgc caatgtgatg atgactggta atattaaaaa tgctgcctac
      721 ctattgacaa agggactata tgagaacaac aaagagctag tccatattgg tcgcaatacc
      781 ttgattatta tcctctcctt tgcccttgga gtggtctgtt ctactctttt atcactatcc
      841 tatggtgagt atgccttatc tcccatgctg atcccattgt gctacgtgaa ctacctcttg
      901 gcacaggaat tttaccatca tcaggtatca ttgaaaaatg attgaagtct actaattgat
      961 atcctcctcc tataattttt gatgactgct tgtttgtcat tgtctattat ggggggaggc
     1021 atcagttaat aggctgagtg atcatttttt tatgctaaaa ttatggtata atgtcagttg
     1081 atagctgaca ggactcagct tgggaatggg tattgcccta gtccctgaat tagaaaggtt
     1141 tcattagcct tgaaaggacg taagatgact aagaaaaaac cattttatat tacaacaccg
     1201 atttactacc cgtcagggaa gcttcatatt ggctccgcct atactacgat tgcctgtgat
     1261 gttcttgctc gctataagcg tatgatgggt tatgacgttt tttatttgac tggtcttgat
     1321 gagcatggtc aaaagattca ggataaggca caggaagctg gcttatcccc tcaagcctat
     1381 gttgatggca tggctgagga ggtcaaggca ctatggaagc tccttgatat ttcttatgat
     1441 aagtttatcc gcaccactga tgactatcat gaggaggtgg ttgctgctgt atttgagagg
     1501 ttgctggcgc aggatgatat ttatttaggg acctattcag gctggtattc tgtttcagat
     1561 gaggaatttt ttacagaaag tcagttagct gaggtttatc gcgatgaagc tggcaaggtc
     1621 attggtggtg tggcaccatc agggcatgag gtcgaatggg tctctgaaga atcttatttt
     1681 ttacgcctga gcaagtatgc ggatagattg gttgccttct ttaaggctca gcctgatttt
     1741 attcagccgg acggtcgcat gaatgaaatg cttaaaaact tcattgagcc aggtctggag
     1801 gatctagcgg tgagtcgaac aacctttacc tggggagttc ctgtaccatc agatcctaaa
     1861 cacgttgttt atgtctggat cgatgctctc ttaaactatg caacagcact aggctacggt
     1921 cagaaggatc atgctaactt cgataagttc tggagtggta gggttttcca tatggttggt
     1981 aaggatattt tgcgtttcca cagcatttat tggccaattt tgttgatgat gcttgattta
     2041 ccaatgccag agcgtttgat tgctcatggc tggtttgtca tgaaggacgg taaaatgtct
     2101 aaatcaaagg gaaatgtgat ttaccctgaa atgctggttg agcgctttgg tcttgatcct
     2161 ctgcgttatt acctcatgcg ttccttgccg gttggctctg atggcacctt taccccagag
     2221 gattatgttg gtcggattaa ttatgagctg gctaatgacc ttggtaacct tttgaaccgc
     2281 acagttgcca tgattaataa atactttgac ggcagggttc ctgcttatgt caaaaacgtt
     2341 acagcctttg atgcggatct ggagcaggtt gtggctgatc atatttccga ataccacaag
     2401 caaatggagg ctgttgatta cccacgtgcc ttagaggccg tatggacgat tatttcacgc
     2461 acgaacaaat acattgacga gacagctcct tgggtgcttg ccaaagcagc tgatagtaag
     2521 gagcagctag ccagtgtgat ggcacactta gctgcaagtc tgcgcgtggt ggctcatttg
     2581 attcagccat ttatgatgac aacctcagct gctatgatgg agcagctagg tctcggtgcc
     2641 aaatatcatc tggaagagct tgatttagca gatcttccga caggtgtgac ggttgttgcc
     2701 aaaggagagc cgatctttcc tcgtcttgat atggaagcag agattaacta tatcaaagag
     2761 caaatgaaaa tgagtacagc taagccgcaa gaagcagact gggatcctga aaaggtagcc
     2821 cttaagtctg aaaaggatac gattactttt gaggccttcg atgctataga gctttgtgta
     2881 gcagagataa aagaggtatc aagggttgaa ggctctgaaa aactgctgcg ctttagatta
     2941 gatgctggtg atggcgaaga ccgtcaaatc ctgtcaggta ttgcagctta ttacccaaat
     3001 gaacaagagc tcgtcggcaa gaaggtgcaa attgttgcca acctcaagcc gcgaaaaatg
     3061 atgaaaaaat atatcagtca gggcatgctt ttgtcagcag agcatgatgg caagctgaca
     3121 gtgctgacag ttgatccggc agtgccaaat ggtgcgatta ttggctgatt gggcttttag
     3181 atgacaatat cccgtatggg tcttgctaat agattgatta gcaggagcat acgggatttt
     3241 tggtgtctta aaaacgaaat aaacaacaat gctttagaca gaagtgctct ttcaaaaatg
     3301 gtatataatg attaaaaaga aagaaatgga tatgcgaatc aagtgacgtt tttgactgat
     3361 atctctttaa actgctactg cgccacagcc ttgtatgacg atgctagtgt taacgtgtga
     3421 acgaacaatg aatcagattg gctagtttat tttgaaagat gctcaacaaa gctattagag
     3481 ttatttgagg tgtcgccttg attttattta ctttattacc ttctgagagg aagatgctaa
     3541 gggagatggc atctaagtct caaatccgta tgtcggattc attatttgtg gcttccaatt
     3601 tcacccagaa gacctatgaa gagagtagtg aaagtaggta attactatat catttcatta
     3661 ttttttaaaa ataaaaaatt ttgttataat ttagaatata tgaaagtata ggagaattta
     3721 ttttagtggg agatattaag attgagattg gcaaaaggat tcgtacagca cgcttagata
     3781 aaagattcac tcagatagat atttgtgatg atgaatctga attgacaata cgacagttgg
     3841 cgcgtattga gaatggacaa gctatgatta cattacctaa gataatcttt ctgtcagaga
     3901 agcttggtat tccagttcag gacttaattg atgaaaaaat agagattcct aaacgctatt
     3961 tggaattgaa aaataaactc ataaaatctc atacttatgg cgataaagag agaattcgtc
     4021 accatgagtc aatgttcaat gaaatttatg aagagtttta tgataattta ccagaagagg
     4081 aacagctatt agtagaggtt ttacaagtta gattagatgt tttttcgagt agaaattctg
     4141 agtttggaat cagtttactt gaggaatatt ttcatcagat tctaaaaaag aagtatcata
     4201 gctataatga ccttttgatt attgacttat atctcttttg ttgtgcggtt ggtttggagg
     4261 ataaaactta ttttgatgat ttatcacaaa aagttctgtc gtacattgac tatagtgatt
     4321 ttgagcgcat atatgtatta gaaaaaatat tgctttctat actgatacaa gtcgaaccag
     4381 agaagtatct tttgtatacg aaagtcttta gagaaattat ggaaacaacg aataattttc
     4441 agcataagcc ggctatctat gcttttgaag caaagtatta tttacaagtg cggaaagatg
     4501 ttgaaaagac gatagagtta tacgataagt cgattatgtt cgcaagaatg cttaatgatt
     4561 cagtattagt aagtaatcta gaaaaagaaa aactagagga cttaggcaac ctgacttaga
     4621 agtcatgttg ctttttttat gttttgaata taataagact ataaaaaacg agacaaatta
     4681 aaaagaaagg agcaaaggta tgattctagc aattatactt acagctttga tttggattgc
     4741 gggatgatac aatcatctat ttgttatcaa atcaaaaaaa tttttatcga gcataaagag
     4801 attaccataa aaaataactc tgactttgat aggttatgta gggttgctat caatcatgaa
     4861 ctgttcaaga ttatatattt aactcttaga gcagaagagg taatcaaata tacaggtgga
     4921 gtaatccgac atatagaagt ttcacgtata gaaattgaag aaggagaata gatggaacaa
     4981 tttaaaaatt taagtcaatc tgaattacaa aacaccaatg gaggaggtgc ttggtctcca
     5041 attgtgacag taccggtacc agttgtttta cctatgaagg tagttaaatg ggtagctggt
     5101 ttctttgaat agcatattaa actaaaaata aaaggaggaa gctataaaag atattcgagt
     5161 ctcaaataga taatagagat actgtaacac acagataaaa tttaaatata aggagaaaaa
     5221 taatatgact agatttgaaa cactagacaa catgaatttt gtatcattat ctgaagcaga
     5281 aatgatggaa atgactggag gtggctttga tattgcagct cctatcaaag ctatttttaa
     5341 cgctggtaaa gaatttggcc gtgcattggc aaagtggatt taaagggta
//
LOCUS       DARYSY010000083         5306 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYSY010000083 DARYSY010000000
VERSION     DARYSY010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5306
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(32..511)
                     /locus_tag="TVR04_001822"
     CDS             complement(32..511)
                     /locus_tag="TVR04_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1270488.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQRIADTIEAVKQIKFPFKKK"
     gene            842..1594
                     /locus_tag="TVR04_001823"
     CDS             842..1594
                     /locus_tag="TVR04_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270489.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            1597..3552
                     /locus_tag="TVR04_001824"
     CDS             1597..3552
                     /locus_tag="TVR04_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1270490.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     LELVFMYLGTVVVGSILSAIFSHVFYLIFANLVRAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIIEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYIYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKTYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKEEYLQSTYVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNILQE
                     VGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLLLFGVLNTSLIYLVSA
                     MTIGVIIVIYFTIYRITSRTYYNIIER"
     gene            3596..4261
                     /locus_tag="TVR04_001825"
     CDS             3596..4261
                     /locus_tag="TVR04_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1270491.1"
                     /translation="MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDLILMDITLPFFNGFYWTTEIRKTSTMPIIFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLSILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILA
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            4258..5235
                     /locus_tag="TVR04_001826"
     CDS             4258..5235
                     /locus_tag="TVR04_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1270492.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLSYFKMTSLTI
                     LTLLILQGFGNYIRFKKKMKILREFIYVNELNQLNSPSEQAYRSLIIKLKEAEAEAAL
                     NQLNNQKNTEALIKMWSHQMKLPLAAMSLMIQTNHTDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVYSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLDITISSQIDQGTLVVIQKKHSKQTKFSTSLL"
BASE COUNT         1680 a          993 c          964 g         1669 t
ORIGIN      
        1 agtatcagct tgttttttaa cagttatagc cttatttctt cttaaaagga aacttaattt
       61 gcttaacagc ttcgatggta tcagcaattc tttgatttcg ttcgacagcc tttagggtct
      121 cttgatctaa aatagcctga cttttctcaa ggacatctac agtaacataa taaagcttca
      181 ctaagcttcc cagcttatgc tttccaggct taggtgacat ggaaacaacc tcatttaagc
      241 tagcatgtat ccatttttta ctaggcttga ccggcaatag tgcgacaaca aaacctagct
      301 gttccaaatg cttttgcgct ttgtcaacag gtaaattaat cacatcatct aaaagcgtta
      361 gctgcatttc cttttcatgc ttttgttcca tatgcttttc gataatggga cgggtgttat
      421 ctattgtttt tcctataatt tcagtggtat cagggataat ggaaaacagc tttccgacag
      481 tccctagcgt ttttttgatt ttcttagcca ttgacgcttc tcctaaatag aattctcctt
      541 tcattatatc aaaatgataa gaaaaatgat gttataaaac ttacaaatct gtaagtcacc
      601 catcaaatct tgtaagctaa ccagactatt aattagggta aactataagc tgtaaagaaa
      661 aaagagttta gcgcaatagg ttcagtcagc taagatggtt cttgttgaga gctgggctgc
      721 ttcatgaaag aagaagtggt taaggctgac aaaaggcact aaatgcatca ctagctaaat
      781 acgtcacgat agtggctata tttaaagcta aaagagtata atagacacaa aggagtttca
      841 tatgttatta gaaattaatc atttagagaa ggtttttcgg acacgctttt caaaggaaga
      901 aactagagcc ttacaagatg ttgattttaa ggttgacaag ggtgagttta ttgccatcat
      961 gggagaatca ggctcaggga aaacaaccct attaaatatt ctggcaactc tggaaaaacc
     1021 aaccaaggga tctgttttat tgaatggcac tgacattaca aaaattaagg agggtgacct
     1081 agctaatttc cgacttcaaa acctaggctt tgtttttcag gattttaacc tcctagacac
     1141 cctatcgatc agagataata tctttttacc ccttgtttta aaccgtaagc catttaaaga
     1201 aatggaaaga cggctcaaca tcattgcccc taagctgcgc attgaaacgc ttttagataa
     1261 acgtccattt gaaatttctg gtggtcaaaa gcaaagggtt gctattgcaa gaagcttaat
     1321 caccaatccg caattattat tagctgacga accaacagca gcacttgatt accgcaattc
     1381 agaggatatt ctcaatcttt ttgaggccat taacctagac ggtcagacac tcttgatggt
     1441 aacacactct gccaatgctg ctagccatgc taagcgagta ctgtttatca aggacggccg
     1501 tattttccac caaatctatc gtggaaataa aacgaattta gaatttagca aagacatctc
     1561 gattgccatg gccggtcttt taggaggtga ataaagatgt tttatctcaa actagcttgg
     1621 aataatctac gaaagtcctt atccgtcaca gctccttttt tactggcaag cactgtttta
     1681 tatatgctca attgtattgt cttgattatc atgatgagcc ccgtatcaga atcgatgaga
     1741 catgggttta tgctattagg actagcaatc tttgttttaa tcatctttgc cactattatg
     1801 gagatttata gctataattt tttactaaag caaagaagtc gagaatttgg tctgtacaat
     1861 attttgggaa tgaataaaaa gcaggttggt ttagtctcaa cgctcgagct tgtttttatg
     1921 tacttaggga cagtagtcgt aggaagtatc ctatcagcta ttttttcaca cgtcttttat
     1981 ttgattttcg ctaatctggt aagagcagtc catttagaat tacaaatcaa tcctgttgct
     2041 tttatttaca ccactttaat cttcgctgct atctttggtt tattagaggt tgttggcttg
     2101 attaaaatca gaaagacctc tcccttaatg ctctttcgtc ataaagaaca gggtgaaaaa
     2161 gagccaaagg gtaatttatt actagcagcc ttatccatca tattgcttag tattggctat
     2221 tacatttcct tatcatcgac aaagctgaca gcattagaca ctttatatcg gttttttata
     2281 gcagttatta tcgttattat cgggacctat ctcttttaca tttcctttat gacttggcac
     2341 ttaaagcgtc gtcgtcaaaa caaggcttat ttttaccagc cagaacattt tgttagcacc
     2401 tctcagatga tttttagaat gaagcaaaat gctgtaggct tagcaaatat taccctctta
     2461 gctgttatgg catttgttgc aatagcaaca acgactgcgc tttatgctaa tagcgaggca
     2521 atgtctaacc agctttttcc taaaaatact catattaatt ttgataattc agagattgac
     2581 aatcaaaaag aggtttttaa tcgacttatt attgaaaaga ctaataagcc tgcctcagat
     2641 tttctagtct attatagtag catggtttct tttgaagtat cccaaaaaga aaccattgta
     2701 gtaaccaaag aatccttatt aaatcctagt ccagtcacta caggctatat ctacttagtc
     2761 actcaagatg atttccgcgc cttgggcaat caattgcctg aattaaagga caatcagact
     2821 gctttcttta agcaaagagg ggatagtcaa ttacgacagc tggatatttt gggtaaaaca
     2881 tataccaatg tcaaaaattt aacatcagta accttcccag aagcagctaa tacctataat
     2941 ggtgcagttc ttgtggtcaa agatatggaa acactaaagg acattcaaga cagcattcaa
     3001 agcattaatc atactggcgg acgggccagc atttcagcct atgctgattt aactaaggct
     3061 gaccttagga gtattagtga tgacaaggga atcattagtg atggcgatac tgttataggc
     3121 catatcgaaa ctaaagagga gtacctccaa tcaacctatg tcttaaccgg tggcttcctt
     3181 tttacaggct ttcttttagg cttgagcttt gtacttgggg ctgcactgat catttattac
     3241 aagcaatact ctgaaggcta tgaggataaa aaatcttaca atattcttca agaggtcggc
     3301 atgagcaaac aacaagtcaa aaaaaccatc aattcccaaa ttgtattggt gttctttatg
     3361 cccatagcta tggcagtcct acatttttgt gtcgctctgg ttatgctcaa gcaaatgctc
     3421 ttgctctttg gcgttttaaa cactagcctc atttacctag ttagtgcaat gaccattggt
     3481 gttattatcg ttatttactt taccatttac aggataacaa gcagaaccta ttacaatatt
     3541 attgaacgat aagacaagtg gcgatttttc gccacttttt tgataaaata atattatgat
     3601 taaagctgga aaaatttata ttgtcgaaga tgacgctgct gtcttaacac ccttaaaaga
     3661 gcacctgagt cagaactacc aggttcttac cgtctctaac tttagagaca taaaacaaga
     3721 ggtgattgat tataaaccgg atctcattct tatggacatc accttaccgt tttttaacgg
     3781 cttttactgg accacagaaa ttcgtaaaac atcaacaatg ccaattattt ttatctcaag
     3841 cagtaatgat gagatggata cggtcatggc acttaatatg ggaggagatg atttcatctc
     3901 taagcccttt tctctatcca ttttagacgc aaaaatcgca gcatttttaa gacgctcaca
     3961 gcaatttagc agtgatgatg tgaccataga tcaatttaag ctacattttg atggtacctt
     4021 atctaatggc acagatagca ttcatttatc gccaacagag cacaaaatct tagcgatttt
     4081 atttactcac ccacagcaaa ttgtgtcaaa ggaagatatt ctagcaaggc tttgggaaaa
     4141 cgagagcttt attgatcaaa acacgctcaa cgttaacatg acgcgtttac gcaaaaaaat
     4201 atcagctatt ggttttgacc gtattcacac agtgagagga gtaggctata ttatcaaatg
     4261 ataagagcat tttttaagga atattattcc tggtatatcc agtatggggt tgttatggct
     4321 ggttatctgc tgatcttttg gctttataga ctgcctctaa gctatttcaa aatgaccagc
     4381 ctaaccatac taaccttgct aatactgcaa ggctttggaa actatattag gtttaaaaag
     4441 aagatgaaaa ttttacgaga atttatttat gtaaatgaac tgaatcagct gaattctcct
     4501 agtgaacaag cctatagatc tttgattatt aagctcaagg aagcagaggc agaggcagca
     4561 ctaaaccagc ttaacaacca aaagaataca gaagcgctga ttaaaatgtg gtctcaccaa
     4621 atgaagcttc ccttagcagc tatgtcctta atgattcaaa ccaatcatac tgatattaag
     4681 gattatcaga tccaggtttt acgcttggag cattacctca acaatctatt aagctatttg
     4741 aaatttaatc agcatagtga cgattttcgg ttccaggttt actctgtaaa gcagcttgtg
     4801 acctcggtta tcaaaaagtc cagccagact tgtatcgcta aggggattag cattgcagtt
     4861 gatggcgatt ggcaattgag cactgacaac aaatggctgt catttgctct gacacaaatc
     4921 attgacaatg caatcaaata ttctaagcca caaggccaca tcaaagtcag cattaaggaa
     4981 ggtagtattt ttatatcaga taatggtatt ggaatactag aggaagattt gccacgtctg
     5041 tttgaagaag gctttactgg ctacaatggc catgagcatc aaaaggcaac tggtttaggc
     5101 ctctttatga caaagcaaat acttgataaa ttaaatttag acataactat ttccagtcaa
     5161 attgaccaag gaactttagt tgtgattcaa aaaaagcatt ctaaacagac caaattctcg
     5221 acttctttgc tgtaaaaaat gatagccata aatctccatg caaaaaagac tgaaagcaca
     5281 gattttcagt ctttttaagt aggtaa
//
LOCUS       DARYSY010000084         5273 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYSY010000084 DARYSY010000000
VERSION     DARYSY010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5273
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..538)
                     /locus_tag="TVR04_001827"
     CDS             complement(<1..538)
                     /locus_tag="TVR04_001827"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: protein motif:HMM:NF020596.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1270493.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTSHVSGEVV
                     EVWPYGQNPHSGTIGVDPGQQNLDTALGRRKAEERIKETLWVDGVKVDDKDFENIKDD
                     RTKSDYFVSEYGKGSGYYDVNKKFDGHDNLLCSGAVATNMFHWWVDQNKGYIEKFKKQ
                     DPENNGFVKFNDGYKKSVD"
     gene            complement(850..1659)
                     /locus_tag="TVR04_001828"
     CDS             complement(850..1659)
                     /locus_tag="TVR04_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1270494.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYISST
                     QALRHKDSQLMLEAANQYNQQQKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPAAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            complement(1740..3182)
                     /locus_tag="TVR04_001829"
     CDS             complement(1740..3182)
                     /locus_tag="TVR04_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1270495.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAADFAKEAGKHLT
                     TVVAGQGEQTITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSAGL
                     SYNKDAKVYVVNGDSRQDITGSFTINDAGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPTGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            complement(3197..5167)
                     /locus_tag="TVR04_001830"
     CDS             complement(3197..5167)
                     /locus_tag="TVR04_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1270496.1"
                     /translation="MKQLTKIVSIVLLLLLTLSASLPKVRATNISDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFEITVRNVTQTTTETTGTTTVRVGNHTATINVTK
                     PEAGTGTSSFYYKTGDMQPDDTDHVRWFLLINNNKEWVADTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGEKALEEFRQKFPYSTITADDKTGHIHVSLDKDDASKNTVNVAY
                     KTKITDYDQKEFANNSKIWYQILYKDQVSGQESNHQVANVNANGGVDGSRYTSFTVKK
                     VWNDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKIT
                     YSVKEVTVPAGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDKENQDGKRPKEIT
                     VRLLANNVATGDVTTASVKTGWKYTFTNLPKYKDGKQITYTIQEDSVADYTTTIQGFD
                     ITNHHEVALTSLKVIKAWNDKDDYYHKRPKEITISLKADGKVIREHQLTPDQQGKWEY
                     TFDQLPVYQAGKKISYSIEEKQVDGYQAPVYDINEDLNQVTVTNTINQSYSLPDTGGQ
                     GVKWYLLIGGSIITVACLVLINLYQKHKHHNM"
BASE COUNT         1348 a         1164 c         1025 g         1736 t
ORIGIN      
        1 catcaacaga ttttttatat ccatcattaa atttaacaaa tccattgttt tctggatctt
       61 gttttttaaa tttttcaata taacctttgt tttgatctac ccaccaatgg aacatattag
      121 ttgctacagc tccactacac aaaagattat catgtccgtc gaattttttg tttacatcat
      181 aataaccaga ccctttgcca tattcagaaa caaagtagtc tgatttggtt ctatcatcct
      241 ttatattttc aaaatcttta tcgtcaactt taactccatc aacccaaaga gtttctttga
      301 tcctctcttc agcctttctt cttccaagag cagtgtctaa gttttgctgc ccaggatcaa
      361 ccccaatagt accactatga ggattttgcc cataaggcca aacttcaact acctcaccag
      421 aaacatggct tgttgttagg aacatcattc ctagcataca tgaggcaagg ccaatagata
      481 attttctcat accgaattta ggtttacgtg agtgtgtgaa tgattgtttt ttcatcatgc
      541 tatcctttct tattataaaa cgttttcaaa aacaacaaat taaataaata tctaatattt
      601 tgtcgttaac tctcctcctt ttatcatttt attaggtttt ataagtcaat tttatcatgt
      661 tatgctcaga tgtcactttt gaaggctcca aatgctcgct cttttaaagc gttttcggtc
      721 actaagaaaa aaaaacgatt tctgtgtttt taatcatggt cgcaatttag cactaaaaaa
      781 gcccctgata ggtcctcagt aacctatcaa gggttgatga tttgacttag ttgcttctgg
      841 aaagcctgct catgctttag acctcctacg ccagcgccaa gtgcctatta gtacgagaga
      901 tagccctaat gcactgatta gcaagagcca gaggattagc ctactaggct tttgagatcc
      961 tcttgcagcg gctggtgtcg ctgttttgat acgatgccct ctgactaaga gccgatgcgt
     1021 gttgacaccg tagggggtac aggtgaccaa ggttaccaga tccttccctt cctctatcct
     1081 taagaggctg acatcatcag gcaaaacggt agcaatctta tccacctgat aggtcatagt
     1141 cctattaaga ctggtgatgg taaaggtatc gttaatcctc agcttatcaa tattggtaaa
     1201 tagcttggca gagggtaacc ctcgatgtcc tgagatgaca gcatgtgttc ccttgccacc
     1261 tacaggcaaa gaggtgcctg caagatgacc gatagccacc tgtaggatct cctcatcggt
     1321 gccatgataa atcggcagcc gttcatgcac ctttggaatg tctatgtagg ccatgatacc
     1381 tgtatttgtc agatccagct gctgctgata ggcttctgcc tcactatcgg tcagggttaa
     1441 atcaggatca tggttagctt tttgctgctg attgtactga ttggctgctt ctagcatgag
     1501 ctgactatcc ttatgtctca aggcttgcgt gcttgaaata tagtcagcga tgagctgtga
     1561 ttggtgctgt gcattccaat agttactaag ggtggggtaa aggacaatca gacagcctgc
     1621 caccaaaatc acactccaaa aaatgacact tttcttcatt ctatagcctc tatcaaaaaa
     1681 agaggtgaat aggtcttggt aagacgtcta tccacttctt tttacctact cacacgatct
     1741 tattgctgtt tctgacgaaa gataaacagc gttgatattg tcattagcat tactccaaac
     1801 acatagagca tggttgttcc gatacttcct gtcgaaggga ggatagaccc ttttttatta
     1861 acaatagttg cggatacggt accagcttct gtatcagcag tgaagccagt tgctttgtca
     1921 acggttaggc tagtcaactg aggatcgtct gactcggttt catgctgcgc tacaatgctg
     1981 aacatgacat ctgcaatagt gttgtaaccg ccaggtgttg ttgtttcgct gagcttgtaa
     2041 tcaccagcgt caagtccaac aaactcaaag ctagttgtat cccctgcttt aatttcttgg
     2101 actatttgat atttttcctc gccattatca cctttgacca gcttataaag ggtaaagcct
     2161 gcacctttta gggctttttg atcttgatca accttattga tgatagtttt ataggtgaaa
     2221 acgataacct tgtcttttgg tgtttcccct gttggagact cctctccttt tccaagagcg
     2281 tttggatcgt ttgagtattt caaagcaact tcgtttggat ttcctttttt gccgatggcc
     2341 gcttggtcat tgagggtagc agtgtattcg acaacgatct tactggtagc tgttattgtt
     2401 actccctgaa cagcttttag gttattgatt ttaaaagatg aaccagcgtc attaattgta
     2461 aatgaacctg taatgtcttg acgactgtct ccattaacca cgtaaacctt agcgtctttg
     2521 ttgtagctta gtcccgccga caaagtatct acgaattcaa ggtagtattc ttggaaggcg
     2581 tcgtaatttg acggtagggt tgcggttagc tggaatggca ccttgtcatt tttgtcatag
     2641 tcagctgaat cttgccagcc tgtctcaaga cctgtcttgt cattacggtc cttgaccttt
     2701 ttaaggactg ttgggatagc agattttggt ttgaagctgg tatttttaac aacctttaag
     2761 acaaatgagg tgtaggcatc atgcttacct gtttgagaat catttttgtc cttgatgagg
     2821 tagtagccag cctcgttaac ggtgattgtc tgttcacctt gtccagctac tacagtcgtc
     2881 aagtgcttac ctgcttcctt ggcaaagtca gctgcatttg cttccttcaa gccctctgca
     2941 atcttagcag cgtcttttga accatcaaat tcaaaaggtg taacaccacc tccccatgtg
     3001 atgtttgata gggtactgtc aaacaagtca cccttgaaaa tctgataagc ctcataggtg
     3061 tgacctgctg tagctccctc aacagtgatg gtatagcttg ctgtatcagc aaatgccttt
     3121 cctgacagca ttgttaggaa ggtgacaagc aagctcgtca agattaattt gattgttttc
     3181 atagctctct cctctattac atgttatggt gcttatgctt ttgataaagg ttaatcagta
     3241 caaggcaagc cacagtgata atactgccac caattaacag ataccatttc acaccctgcc
     3301 ctcctgtatc aggtaggcta taggattggt taatggtgtt agttacagtg acctgattta
     3361 ggtcctcatt gatatcatag acaggtgctt gataaccgtc aacctgcttt tcttcaatgc
     3421 tatagctgat tttctttcct gcctgataga ctggcaactg gtcaaaggtg tactcccact
     3481 tgccctgctg atccggtgtt agctgatgct cgcgaataac cttcccatca gcctttaagg
     3541 aaatggtaat ctccttggga cgtttatggt agtaatcgtc cttatcattc caagccttga
     3601 tgacctttag gctggtcaag gctacctcat gatgattggt aatatcaaag ccctgaatgg
     3661 ttgtggtgta atctgccaca gagtcctctt ggatcgtata ggtgatctgt ttaccatctt
     3721 tgtatttcgg tagattggta aatgtatact tccagccggt ttttactgag gcagttgtga
     3781 catcacctgt cgcaacgtta ttagccaata gacgaaccgt aatctcctta ggacgtttac
     3841 cgtcttggtt ttccttgtcg tcccaggttt tttgtccagt aatgctaatg acctctggcg
     3901 tataggtatt ggtaatggta aagcctactc cactatcacc ctcaacctgc gattggtagc
     3961 cagcaggaac cgtcacttcc ttgacactgt aggtaatttt ttggttctga ctgtcatact
     4021 tatccagctt accaaaactt gcttgccagc tattagtatc actcaattca atggtcttat
     4081 cattaacttt ctgatcattg gcgtaaagct gaacagtaat agtctttgga cgcttaccgt
     4141 cttgattttc cttgtcattc caaaccttct tgacagtaaa gctggtgtag cgactaccat
     4201 caaccccgcc gttagcatta acattagcta cttgatgatt ggattcttga cccgatacct
     4261 gatccttgta taaaatctgg taccagattt tactgttgtt ggcaaattct ttttggtcat
     4321 agtctgttat cttagttttg taggcaacgt taacggtgtt tttcgaagca tcatctttgt
     4381 ctaagctgac atgtatatga ccagttttat catctgctgt aatagttgaa tatgggaatt
     4441 tttgtcgaaa ttcctccagc gccttttccc caacaaagcg ctcattacga taaccagata
     4501 ccgtgatatc aaagctgctc atatccaagg tctgaccacc ctgaatgtcg tcttcaactg
     4561 taacagtatc tgctacccac tccttgttgt tattaatcaa caagaaccat ctcacatgat
     4621 cagtgtcatc aggctgcata tcaccagtct tataataaaa tgagctggtg ccagtgcccg
     4681 cttcaggctt ggtaacattg atggttgcag tgtgatttcc cacccttaca gtggttgtcc
     4741 ctgttgtttc agtggtggtt tgtgtcacat ttctgacagt aatctcaaac tctccccaac
     4801 cagagacatc atgcattgtt tcaatatttt gattgaatgt gaaaacagcc ttgtctagcg
     4861 tgacctccaa ggtaccaaca tctacccctc taatattaag cggtatggtt ttattaaagc
     4921 cctgaatgta gacattacca cttgtaggcc aagtgacctc tatcgtgtct cctgctttga
     4981 ttttctgttt tttgtcatca aacgcgacct ttaccgtcgt tctctctcca tctcggagtg
     5041 atgaagaagc aaccgtcaat gatgtgatat tgtcgctaat gtttgtcgct cgaaccttgg
     5101 gcaggctagc actaagcgtc agcagcagca acaacacaat actaacgatc tttgtcagtt
     5161 gtttcaagca aaatcctcct tttacattat tgatttgcaa aatttaattt tacaaatcac
     5221 atccatcatt gtataatgtt agcgaaaaat attatgtaca aaattaacat taa
//
LOCUS       DARYSY010000085         5271 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYSY010000085 DARYSY010000000
VERSION     DARYSY010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5271
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            266..1174
                     /locus_tag="TVR04_001831"
     CDS             266..1174
                     /locus_tag="TVR04_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1270497.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNSKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            complement(1305..2090)
                     /locus_tag="TVR04_001832"
     CDS             complement(1305..2090)
                     /locus_tag="TVR04_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1270498.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQIANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNALFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKKLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLISLAVFSGVNYIKEPFYFDVVNAVIAKELLDSAKP"
     gene            complement(2181..2990)
                     /locus_tag="TVR04_001833"
     CDS             complement(2181..2990)
                     /locus_tag="TVR04_001833"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1270499.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGKLAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRDTARLVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            complement(3204..4415)
                     /locus_tag="TVR04_001834"
     CDS             complement(3204..4415)
                     /locus_tag="TVR04_001834"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1270500.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            complement(4493..5176)
                     /gene="rpiA"
                     /locus_tag="TVR04_001835"
     CDS             complement(4493..5176)
                     /gene="rpiA"
                     /locus_tag="TVR04_001835"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1270501.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMR
                     EDKRLITDMQNFIIDLDLGCIENPFEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
BASE COUNT         1577 a         1247 c          984 g         1463 t
ORIGIN      
        1 agagcaatgg aaaaataggt attatctgac attatcacga ttacttttta ccgttcaaga
       61 ccagccgttt atcaaaacac agacatgcca aaaataagcg ttaaaaagca ttaaagctgc
      121 ctatttggca gctctttttt gtctgggtac gacgctagca tcaagctagc ttcaccgcac
      181 aagctaggct accgcttgtg aagtcttgtc ctaagctcta ataaaggcac ttgattcttt
      241 atactattta agatagactg tcagtatgag aatccaacaa ttacaatata ttataaagat
      301 tgttgaatgc ggttccatga acgaagccgc taagcaatta tttatcacgc agcccagtct
      361 gtctaatgct gtcaaggaat tagagcagga gatgggcatt actattttca ttcgtaattc
      421 caaaggcatt accttaacca aggacggggt tgagtttcta tcttatgcca gacaaattat
      481 tgaacaaaca gcactgctag aagatcgcta taaaaatcac aatactagtc gtgagctctt
      541 tagtgtttcc tctcagcatt acgcctttgt tgtcaacgct tttgtgtcct tgctaaagcg
      601 agctgatatg acccagtacg agcttttctt gcgagaaaca agaacctggg aaatcattga
      661 tgatgtgaaa aatttccgct cagaaatcgg cgttttgttt atcaatgact acaaccgaga
      721 cgtccttacc aagctgtttg aggaaaatca tttgaccgtt tctaccctat ttaaaaccac
      781 accgcatatc tttatcagca agtccaatcc tctggcaaat aaaaccagct taaccattga
      841 tgatctcctt gattttcctt atctaagcta tgaccaaggg attcacaatt ccttttattt
      901 ctcagaggag atgatggcac atatccctca tagcaaatct attgtggtga gcgaccgagc
      961 caccctattt aatctcatga ttggtttaaa tggctacacc gttgccagcg gtattttaaa
     1021 cacaaatcta aatggagatc agattgtcgc tattccctta gatgttcctg atgtgattga
     1081 gattgtcttt atcaagcacg aaaaagctaa cctctcaaaa atgggagagc gatttattga
     1141 ctacctgcta gaagaaatta gcttcaatca ttaattgact actagctaaa cacaaaaaac
     1201 ctgaaagacc tgttctaagg ctctaagctg actagtcaca gctagcttag agaagcctcg
     1261 ttcagatcgt tcaggttttt tattattgct aatctttcaa gtagctaagg cttggcgctg
     1321 tctaacagct cctttgcgat gacagcatta acgacatcaa aatagaaggg ctctttgata
     1381 tagttaacac cagaaaaaac tgctaagcta atcaaaccat ctagaaaggc ttgagaagaa
     1441 aaatgagttg tccgatatag ctcctcctca tcaaagggtt tgatcaaatg agctagggga
     1501 ttgcggactg atttttcaaa ctgccttaag actaccacta acttcttaat atcagctgga
     1561 agctccgata aaacaagtaa atcagccagg ctacgtgtcg tcacatgacg cggctgtctt
     1621 tgtgccagat agctcctaaa gagggcatta tcggcttttt ccattgcctt aaaattccaa
     1681 gtgtcatatt gatcattctt ggtatcaata atatagcttt gaacatctgg gacagcctgc
     1741 tcaagcagcc gcaaaaagag acgatataag acaggggaca ctgacctcac aaaatcaata
     1801 atctcaccgt ttttgacctt agctgccaaa tcaagcaggt aatttgcaat ctgctcctcc
     1861 tcttgggctt catttaacaa aagcttaacc tgatgtctat cctcaataag cctattttcc
     1921 gccctatgtt gaaaggcata agcaacgtta agctctcttc tttcctttaa aagctcaagc
     1981 aaataaagta ccttgggtga aaaatcaggc agagttcttg caattttgta ggcatgacta
     2041 taagcataaa cttctaaaag aatacttatc gtatgttcca tatcagtcat cactctaatg
     2101 tcccaatcct tatttttcct catcttatcg atcaaaggac tagcagcgac ccagcgttac
     2161 cgctaaccta agagcaagcc ttaaagctct gccaaaatag ccttaaccaa gcctttaaag
     2221 ttttccttga tacgctcagt tacctctaca acctcttcat gattaagctc tgattggaag
     2281 cccgctgcaa agttcgtaat cgctgaaatt ccaagcacct tcaagcctga gtgggcagcg
     2341 ataataacct ccggcacagt tgacatacca acagcatctg ctcccataac cttaaaggca
     2401 cgaatctcag ctggtgtttc ataggttggt cctgaacagc caaggtaaac tccctcttgc
     2461 aggtctaggc ctagcttttc tgctaccaaa cgagctgtat cacgataagc tgctgtataa
     2521 gcatcagaca tatccgggaa gcgtggacca aattcatcta ggttttcgcc aatgagcggg
     2581 tttgttcctg tcatattgat atggtcattg attagcataa gcgttccagg accatagcca
     2641 ataccacctg ctgcatttgt caccagcaag ctatggcagc ccagtgcctt catcacacgt
     2701 accgggaagg tcacaacctc cattggattg ccttcataga aatgaaagcg cccttgaagt
     2761 gccaatacct tacggccagc cagcttacca taaactaatt ttccggcatg accaacaact
     2821 gttgatttgc cccagtttgg aatatcagca taatcaatca caatcgcctg ctcaacctca
     2881 ttggctagct cacctagacc agagcctaga atgagaccaa attcaggctt gtcaataccc
     2941 ttgctttcta ggaaagcctg tgtttcacga attttttcaa gtaatgtcat cttatttctc
     3001 cttttatctt attttatttt ttactataaa acatgcttct cttgagcttt ttgctgtagc
     3061 aaagtccaat aaatcaacta atatcacacc gatcatcagg actagacaac ctgccacaag
     3121 cctattaata gacctaacca cagcgctggt tttcagtttg atacgccaag ctcctttgcc
     3181 tatcaaatgg tatttgctca ctcctatacc aagtcagcta agaatgatgt tccaatcata
     3241 gcagtgtcca caccgaagtt ttcggcaata gtcgctgaaa tatcagcaaa atgtccctgt
     3301 ggaatcacac ctgctccagt gcaggaggct gagtaagcaa gcaatggaat atactcacgt
     3361 gtgtggtcag ttccagcata ggtcggatca tttccatgat cagctgtaat caagagcaga
     3421 tcatcgtcct tcatgttggc aatgatctct ggcaggcgac gatcaaattc atgcaaacag
     3481 tcacgatagc cctctggatc acgacggtga ccaaagctag catcaaaatc aactaagtta
     3541 gtaaaagaaa ggccttttgt aaatgctggc agctgcaagg ttttgatcag ggtatcaatc
     3601 ccatgactgt tagacttatt gtgccccata tcgttggtaa ttcctgagcc attaaagata
     3661 tcattgattt tcccaacagc ataagtagaa atcccagcgt cagccagctt atttaagaca
     3721 gtgtcttgga acggtgagac tgcataatca cgacgattag ctgtgcgagt gaagctacct
     3781 ggctctccta tatacggacg ggcaataata cgacctaaaa gagcaggacg ctcaagggta
     3841 atggaacgcg catactcaca aatccggtaa agctcctcaa caggaatcac ctcctcatgt
     3901 gctgcaattt gcaatacagg atcggcagag gtataaacaa tcagctcacc ggtttccatt
     3961 tgacggggac caaaatcatc aatcaccttt gtccctgagt aaggcttatt ggcttcacga
     4021 atgaccttac ggcctgaaaa agcttcgatt ttttggataa tctcctctgg aaagccatcc
     4081 cagaaggtat caaatggctc agtaatattt aagcccataa tttcccagtg acctgtcatg
     4141 gtatccttac caagagatac ctcttctaat ttggtgacat agccagtagg atcagcctca
     4201 gctggaactg tctttagggg gacaggacga ggaatatgac caagtccaat ttttgccata
     4261 tttggaacag ccagaccagc tgtctctgaa atatgaccga gggtgtcaga atctgtatca
     4321 gctacaccag cattaaagaa tttgtcggca tctggtgctg caccaatacc aacagaatct
     4381 agaacgacta agtgaatacg attaaatttt gacataagtc tccaatctag gggaggttac
     4441 ggttggctcc ccaaaaccta taaaataata taaaacatga ttgagctagg aattaggttg
     4501 actgattagc ttcaaggacc gttacaccag cctgaccagc aacaatgacc ttatcaacca
     4561 taccattgaa aaggccatgc tcgacgacac caacagtttg atctagcaga cgcccaaatt
     4621 caaaaggatt ttcaatacag ccaaggtcaa ggtcaatgat aaagttctgc atatcagtta
     4681 tgagacgctt atcctccctc atgcgaaaag agggcttata gccagccctt tcaaagactc
     4741 gaaacagcct gtcagcaccg tattgaacga cctcaacagg gagcttgaaa gcacctaaat
     4801 gatccaccag ctttgattca tcaacaaccc agatatattc cttggtcggt gttgcaacaa
     4861 ttttctccat caatagagct gctccaccac ccttgatacc attaaaggcc ttatctacct
     4921 catcagcacc atcaacagtc aggtcaatgc aatcaatatc atcaattgat gttaggggaa
     4981 tacctagccc ctctgcctgt ttggttgtca cacttgaggt tgtcacacca acaacctgta
     5041 gtccctcttc cttgatgcga cgtccaattt cttcaacaaa gtaataggct gttgaccctg
     5101 ttcctaatcc aatggtcatt ccatctgtaa catattgcgc agctgtcaca ccggcaatct
     5161 ttttcagtgc ttccatgatt cccccttatc ttataataaa atgcttccta gcaccttatt
     5221 ataccatgaa agcgcaaact tgttaataat atctcacact gtttggtcaa t
//
LOCUS       DARYSY010000086         5050 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYSY010000086 DARYSY010000000
VERSION     DARYSY010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5050
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            6..932
                     /locus_tag="TVR04_001836"
     CDS             6..932
                     /locus_tag="TVR04_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270502.1"
                     /translation="MARKHLNKYARRYGLTSAAIVLMAAAIGSGTSVQAQERDLKVLI
                     DKISKYSSVDEFVQRNHSIVGNHYTTISIKNYLHMLERYFKDYFNVLNEELKIPGPRG
                     ERGPQGLPGDKGETGERGETGPAGPIGPVGPAGPRGERGLQGLPGDKGETGERGETGP
                     AGPIGPQGPKGDQGEIGPQGPKGDQGEVGPQGPKGDQGEVGPQGPKGDQGEMGPQGPK
                     GDQGEVGPQGPDSSQGEQGQESKPDMPAPKAPEQIPAPQAPSTATKMVSRPQKAAALP
                     ATGETSNPFFSLAALSIIASAGMLTLKEKKDR"
     gene            1692..3209
                     /locus_tag="TVR04_001837"
     CDS             1692..3209
                     /locus_tag="TVR04_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270503.1"
                     /translation="MSIDNLFTKQQWRELELITLLSETKNPLYYKDACQLLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSSLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLTEVKIDFAIFRHLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLGK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDINE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            3384..4535
                     /locus_tag="TVR04_001838"
     CDS             3384..4535
                     /locus_tag="TVR04_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270504.1"
                     /translation="MKSCKSTLRKAVMAAMLAGAITTTGGVKANEYNGILDSGSSLKK
                     QMADLFVKLGVTESGALIASVDSNIEVEKKLKSIFKNADVADLKVLMGKLGEEGGDLE
                     AYKKLLGEKVNLTRLLVDELKNRITSEESLKKEKSKLESDLTSARDKSAELLSELDEA
                     YKVNEEEGAKNTDLANKLLTAQAEIDQLTQDKAKAASDLETANANITTLQEELAGAKA
                     NVDKLSEEKAAADQALADANARVSELEQEVAAANNRVADLEAQLAEKTAELDVVKADK
                     AELEAKVKELQDMLQQKDRSNADLQANIERLKQELADKFKDQAQPRSKTPQASNSVAK
                     QKASRPAAKPAGQLPSTGEDAANPFFTAAAVAIMTGAGLVTVMPKRQKN"
BASE COUNT         1589 a          878 c         1130 g         1453 t
ORIGIN      
        1 agaaaatggc aaggaagcac ttaaataaat atgctcgccg atatgggtta acatcagccg
       61 caattgtcct tatggccgca gccattggtt caggaacaag tgtccaggcg caagaacgtg
      121 acttaaaagt tctcatagat aaaataagta aatattctag tgttgacgaa tttgttcaaa
      181 gaaatcattc tatagttggt aatcattata cgacgatttc tattaagaat tatctacaca
      241 tgttggaacg atattttaaa gattatttta acgttttaaa tgaggaactt aaaattcctg
      301 gtccaagagg ggagcgaggt cctcaaggtc tcccaggtga taaaggagaa acaggtgaac
      361 gaggcgagac aggccctgcc ggcccaatag gtcccgttgg tcctgctggt ccaagagggg
      421 agcgaggtct tcaaggactc ccaggtgata aaggagaaac aggtgaacga ggcgagacag
      481 gccctgccgg cccaataggt ccccaaggtc caaagggcga ccaaggtgaa ataggtcctc
      541 aaggtccaaa aggcgaccaa ggcgaagtcg gtcctcaagg tccaaaggga gatcaaggcg
      601 aagtcggccc tcaaggccct aagggcgacc aaggtgaaat gggtcctcaa ggtccaaagg
      661 gcgaccaagg cgaagtcggt cctcaaggcc cagatagttc tcaaggcgag caaggacagg
      721 agtctaaacc ggacatgcct gcaccaaaag ctccagagca aatcccagca cctcaggcac
      781 caagtactgc tacaaaaatg gtttcaaggc ctcaaaaagc agcagctctg ccggcaacag
      841 gagagacaag caatcccttc tttagtcttg ccgctcttag cattatcgcc agcgctggta
      901 tgctaacact taaagaaaaa aaggataggt aatatagtcc tggtttgctt gatagatggt
      961 ggttggcaac caaccattcg agtactttcc ttaactataa actcctaatc aattctagcg
     1021 tttaaaaaat aagattattc ttggagggaa gcaaagggct tctctccttt ttgagttgta
     1081 gcattcttga tcctgatctt ataagcagag tcctgtttgc cgggctgttg agatgaataa
     1141 gggcatttct atagtgatta tatagtgtta cagatgtgtg tatgatttaa ggtctaaata
     1201 cccttaaagc ttagttcttg ggcagtcagt tcggattggc tggctgattt ttaagccttt
     1261 aatggcttag tagtaagaca aaccagctta cgtttgctaa aaagccccta aggctataat
     1321 cattttttgt gactaagata aaaactagac cttttgggat ttgtaataat ttagattgtt
     1381 gtttttaaaa ttagcaaata ttaaacactt ttttattgaa tatacagatg atagtaatgg
     1441 cagagctaaa aaataagaga aaataaaaaa gtctacaatt tataatgtaa taaaaaaatg
     1501 agctgactgt tgtgttttaa aggcttttgt ctatttgtaa tcggttaatt tgcgaacaat
     1561 tctaaggtat ttctggctaa tagtatgcta taatgcaact ctattctaca accgacatta
     1621 agagttaatg aaatagtgtt gtgttgcggt aagtttttaa tcaggaaaag tatatttagg
     1681 agctagatac catgtctata gacaatctct ttaccaagca gcaatggcga gagcttgagt
     1741 tgattacctt attaagtgaa acgaaaaatc cattatatta taaagatgct tgtcagctgt
     1801 tggattgttc ggttttaacg ctgcaatcgt gcatcacgaa ttctgttttt atggaagatt
     1861 taggcaagtt gttctacaag gattctcaat ttcatattca ttacaatcat caaagtagct
     1921 taaaggaggt ttatcggaga gccttgctag agtctccttc tcttcagttg atgtcagcct
     1981 tgttttttga tgattttgcg tcattagatg atcttgcaga ggcacttttt attagcttgt
     2041 caaccttaaa gcgcttgatt cgtaaaacca atctctattt aaaagagcat tttgatatta
     2101 tcatttcggc taagcccatt cgtgtagttg gagatgaata caatattaga ctgttttaca
     2161 tcaagtattt ttcagaagca tatacctttt ctgaatggcc ttttgcttct ctacttaatg
     2221 aaaaccacca tgagcaattt gttcaattaa tggcatcttt gacagaggtt aagattgatt
     2281 ttgcgatttt tcgtcacctc aagctattaa gtgcggttaa tctcattcgc tacctcaaag
     2341 gctttaaaat tgggaagcat aaagcactga gtagtctttc gctggagttg ttacaggatt
     2401 ctcaggagat gaaaaagctg tcgcatttgt ttgtgcttaa attttcagta ccgcttgatg
     2461 agcttgtctt gtcagaaatg ttttccaatt atttagatga tgatttggta ttaggaaaat
     2521 ccttgcaggt agataaggtt aaggaggagg ttccgggtcc tcagtccttg ctgagctgga
     2581 tagatttgct tagtgaaatg gagggagcta caggtattgt attgccaaat aaatatgagg
     2641 ttgccagata tcttcatgcc actgttattt taggagtgga ggatattaat gaaagctttc
     2701 tgatttacga ttataaaaag gattacttgg ccttctttaa ggagcattat acctatgttt
     2761 attttaggtt taccgattat gtgaagaggc tatttaagga cggggatatg gagcttgcta
     2821 ctaatttgct caacaatttg gtttattcct tgctgatagc ctgggagaat ttctttttaa
     2881 ccatgtgtga attgatgaaa aaaccaaagc tcttgattat agaaagaagt catggcagta
     2941 cgggaagctt tttgaaaaaa tacattggtg aattttttga gattaccatt tttgataaat
     3001 taaccataga agccttgtgt ctacagcatg actatgacgt cattatcact gatacggtca
     3061 ttaggggctg tgagcatgct gatatctttt tctttagtcg atttgtgcca accgttatag
     3121 tcgccaagct taaccattat ctaagaaaac gaatgggtag tatctttgaa acgaaaacaa
     3181 ctaacaagct tgggaacatc ggctattgat agatatcggt atatttcatt aaaatagcca
     3241 caacttgtca tggtgtaaaa ttagtgagct ttgttaatcc aataaaacta ggtagaatat
     3301 agctataggc taacgtgtaa ctcccttagg gagtaggtgc tttggcctgg gaaagaggaa
     3361 aataaaaagg agaaacaaac aacatgaaga gttgtaaatc aaccctacgt aaggcagtta
     3421 tggccgcaat gctggcaggt gctatcacaa ccacaggagg agtgaaggcg aatgagtata
     3481 atgggatatt agacagtggt tcaagtttaa agaaacaaat ggctgatctt tttgttaaac
     3541 taggagtaac tgagagtgga gcgttaattg caagtgttga ctctaacatt gaagttgaaa
     3601 aaaagcttaa atctatattt aaaaatgctg acgtagctga tttgaaagtt ttaatgggta
     3661 aattagggga agaaggaggg gatcttgaag catataaaaa attactaggc gaaaaggtta
     3721 atctcactag actattagta gatgaattaa aaaatcgcat tacttctgaa gaatcgctaa
     3781 agaaagaaaa atctaaattg gaatctgact taactagtgc tcgtgataaa tcagctgaat
     3841 tacttagtga gcttgatgaa gcatataaag taaatgaaga ggaaggcgct aaaaataccg
     3901 accttgctaa taaactctta acagctcaag ctgagattga tcaattaaca caggacaagg
     3961 ctaaagcagc gtctgacctt gaaactgcta atgctaacat cacaacgctt caagaggagc
     4021 tggcaggtgc taaggctaat gttgataagc tttcagagga aaaagctgcg gcagatcagg
     4081 cacttgctga tgctaatgcc agagtatcag agcttgagca agaggtagca gcagctaata
     4141 atagagtggc tgaccttgaa gcgcaattag ctgaaaaaac agccgagctt gatgtggtta
     4201 aggcagacaa ggcagagctt gaggctaagg tcaaggagct tcaagatatg ctccagcaaa
     4261 aggatcgtag caatgctgac cttcaagcta acattgagcg cttgaagcag gagcttgctg
     4321 acaagtttaa ggatcaggca cagcctcgtt ctaagactcc tcaggcatcg aactcggtcg
     4381 caaagcaaaa agcaagtaga ccagccgcaa aaccagcagg tcagttgcca tcaacaggtg
     4441 aagatgcagc aaatccattt ttcactgctg ctgcagttgc gattatgaca ggtgcaggcc
     4501 tagtaacagt catgccaaaa cgccaaaaaa attaagctat tctcaattct ctccccttta
     4561 actattgttt tatagcattt tactaatgga cattggcatt cctataagct ctattgagcc
     4621 tcttatctga tagaaaggat aaggggcttt ttagtagctt agcaagcact ccttggtcaa
     4681 gttcaatacc tctttgagag cttaaaacta gagctagacc ggatctgaaa ccaagtgagg
     4741 tcatagtggg tattgggctg ttttatgagt ttgctcgtaa ggcttgagct tatgcgtcgc
     4801 agagacgcgc tatctagtct aaagggcttt agcaatgtcg tgacaaacgc atgaagacag
     4861 ttacgctttc tcatagcgag ttttcatcat cactatagtc tttttggtaa catgttatgg
     4921 aatagtcaaa tagcaatcgt gaagctagtg atcttgcaat gcaaaaccgc tgaacataga
     4981 ttaaaaaaat gcatgcagct agaaaatggt tacatgcatt tttgtgatgc caacgtcgtg
     5041 gcagcaatat
//
LOCUS       DARYSY010000087         4988 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYSY010000087 DARYSY010000000
VERSION     DARYSY010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4988
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            39..302
                     /locus_tag="TVR04_001839"
     CDS             39..302
                     /locus_tag="TVR04_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEL1270505.1"
                     /translation="MDTKYCQCCGMPMGEGTELYGTNSDGSVNEDYCKYCFEKGEFTF
                     KGTMEEMIEICVPHVVEANKDMNEDSARKMMMEFFPTLKRWKE"
     gene            309..851
                     /locus_tag="TVR04_001840"
     CDS             309..851
                     /locus_tag="TVR04_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEL1270506.1"
                     /translation="MPRPTTKNDLMIAAKENYEKLNLFISKMTEEELNTPFDFSKDEK
                     KKEAHWKRDKNLRDVLIHLYEWHQLILNWVHSNQKGEEKPFLPEPYNWKTYGDMNVEF
                     WKKHQNTSLEDATKMFHKSHRDVLELAEKFTSEELFSKGVYKWTGGSTLGSYFVSTTA
                     SHYDWAMKKLKAHQKKCKSK"
     gene            870..1748
                     /locus_tag="TVR04_001841"
     CDS             870..1748
                     /locus_tag="TVR04_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000545650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEL1270507.1"
                     /translation="MHFTKVKGILSSKNGMNLFRGCTHGCIYCDSRSNCYRMNHKFED
                     VEVKENGISLLEENLKRKRKKCMIGLGSMTDPYIKEELGLNYTRQALEIINKFGFGVT
                     LITKSANVLRDLDLLKEINSKTKCVIQMTLTTYDEELCKKIEPNVSTTKERVEALKIL
                     RDEGIPTVVWLTPILPFINDTEENILGILNCCKEAKVFGIVCFGMGVTLREGNREYFY
                     SQLDKKFPKLKEQYIREYGNSYVANSVNNKKLMGVFHEFCERNGIVHDNEAIFNYLGL
                     FEGKDISKQLSFFDLI"
     gene            1991..2401
                     /locus_tag="TVR04_001842"
     CDS             1991..2401
                     /locus_tag="TVR04_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1270508.1"
                     /translation="MAKEYYLYVSGQKVKVSEDIYKVYWREKEHEKYLEQVDRKNHLL
                     FFSSLDHDGHYVDNIIDENVDVAKIVETQMMIESLRYAISKLNDEERDIIERLYFNDE
                     TLRSVARLKSITHPALIKRRNKILEKLKKFIEDL"
     gene            2857..3057
                     /locus_tag="TVR04_001843"
     CDS             2857..3057
                     /locus_tag="TVR04_001843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270509.1"
                     /translation="MIIEELEGGVRVDNDWNGLADLIANLITKYAGVLDLDNLPDPMP
                     VNNNSENENIFDMVKTQIEKMK"
     gene            3142..4818
                     /locus_tag="TVR04_001844"
     CDS             3142..4818
                     /locus_tag="TVR04_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1270510.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKAFALYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQTM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAREGKWNG
                     GFAPYGYQLVDGKLFINEEEAVAIRTIFDQYVNTTIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLIAEGIHEAI
                     ISDELWQAAQVKLKSQAKKYEHVNKGKDIRTHLLSGIVKCPVCGVGMFGNKCIKKRKD
                     GTKYKDFYYYGCKHRQMMRGHKCTFSKQIREELLDDAVAEVIIKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDADDKHYKRRKQDLDDRLYR
                     MYDKIEELESFLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLITAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDEDLNIGLDNDEQVECVALLVKA"
BASE COUNT         1909 a          614 c         1045 g         1420 t
ORIGIN      
        1 atataattat cttaaataaa gataaggagg aataaaaaat ggatacgaaa tattgtcaat
       61 gttgtggcat gcctatggga gagggaacag agctttatgg tacaaattca gatggaagcg
      121 taaatgaaga ttattgtaag tattgctttg agaaaggcga atttactttt aagggaacaa
      181 tggaagaaat gattgagata tgcgttcctc atgtagtcga agccaataaa gatatgaatg
      241 aagatagtgc aagaaaaatg atgatggagt ttttcccaac tctaaagaga tggaaggagt
      301 aaaaaattat gccaagacca acgacaaaaa atgatttaat gattgctgct aaggaaaact
      361 atgaaaagtt aaatttattt atctcaaaga tgactgagga agagttaaat acaccatttg
      421 acttttcaaa agatgaaaag aaaaaagaag cccactggaa aagagataag aatctaagag
      481 atgttttaat ccatctctat gagtggcatc agcttatttt gaattgggta cattccaatc
      541 aaaagggaga agaaaaaccg tttttgcctg agccgtacaa ttggaaaact tatggagata
      601 tgaatgtaga attttggaag aaacatcaaa atacttctct tgaagacgca actaaaatgt
      661 ttcataaatc ccatagagat gttttagagt tggctgaaaa atttacaagt gaagaattgt
      721 tttccaaagg cgtctacaag tggacagggg ggagtacact gggttcctat tttgtaagta
      781 ccactgcaag ccattatgat tgggcaatga aaaaattaaa agcccatcag aaaaaatgca
      841 aatcaaaata attggaacag gatagtaaag tgcattttac aaaggtaaaa ggaatattat
      901 cttcaaaaaa tggaatgaat ttgttcagag gctgcactca cggttgtatt tattgcgact
      961 caagaagcaa ctgctaccgg atgaaccata aatttgaaga tgtagaagta aaggaaaatg
     1021 gaatcagtct tttggaagag aacctaaaac gaaagcggaa aaaatgtatg attggtttag
     1081 gttctatgac tgatccatac attaaagagg aacttggact aaattataca agacaggcac
     1141 ttgagataat aaataaattt ggcttcggtg taacgcttat aacaaagtca gctaatgttt
     1201 taagggattt agacttattg aaagaaataa attcaaaaac aaaatgtgta attcaaatga
     1261 cactaacgac ttatgatgaa gaactttgta aaaagataga gcctaatgtt tcaacgacaa
     1321 aagaaagggt tgaagcatta aaaatattgc gtgatgaggg aataccaaca gtagtttggt
     1381 taacaccgat attaccattt attaacgata cggaagaaaa tattcttggg attttaaact
     1441 gctgcaagga agcaaaagtg tttggaatag tatgctttgg tatgggagtt acactcagag
     1501 agggaaatag agaatatttt tattcgcagt tagataaaaa gtttccaaag ctgaaagaac
     1561 aatacatcag agaatatggc aatagttatg tggcaaacag cgtaaacaat aaaaaactaa
     1621 tgggtgtatt tcacgaattc tgtgagcgga acggtatcgt tcatgataat gaagcaatat
     1681 ttaactattt gggactattt gagggaaagg acatctcaaa gcagcttagt ttttttgact
     1741 taatctgact aaggggggtg aaatatttat aaaattataa ttaaggaggg atttattaat
     1801 gaaagtgtta atttttaaca tatacgatac aaatataata atgtcccttt tttacaacct
     1861 ttttttcatt atttaatcat gataatttag tatttttctt ccattacgga ggactcggta
     1921 tgctcaaatg ccgaagtcct ccttttttgt ctgaaaaaca aacagacaaa aaagaaatgg
     1981 aggaaacttt atggcaaaag agtattacct ttatgtcagc ggacaaaagg tgaaagtcag
     2041 tgaagatatt tataaagtct actggcgaga aaaagaacac gaaaagtatt tggagcaggt
     2101 ggacagaaaa aaccacttgc tctttttttc gtcattagat catgatggac attatgttga
     2161 taacatcata gatgaaaatg ttgatgtagc aaagattgtg gaaacacaaa tgatgattga
     2221 atcattgaga tatgctatat caaagctgaa cgatgaagaa agagacatca tagagcgttt
     2281 gtactttaat gacgaaacgc ttcgttcagt agcaagatta aaaagtatta cacatccggc
     2341 tttaatcaag agaagaaata aaatccttga gaaactgaaa aagtttattg aggatctata
     2401 aacttcggta accaaagggg tcaaactttc cttatataaa gtgaagggga gtttgatctc
     2461 ctttactttt ataagagata tagcctattt atggcaaaca ggaagatgta aagaaaatcc
     2521 ctttcaaata attgttcttt gacaactgaa tagaccatga cgggactttt aattacttag
     2581 tgagcgaaag aaattttacg ccataacttt cctgctgaag aaattcggtt taaatgaata
     2641 ctgtcaaaga caaggatata aggaaacgag cgataaataa attttcttaa agcaaagagc
     2701 gaggataact ttgcaagtga tgacctaagt aatgataatg atacttcttt agtgaaagcc
     2761 ggctcatctt aacaggggcg gtggtgagat tccaatgttg ctgatcctaa gcacccgtca
     2821 atgtcattaa acttggttag atgagaaaat tatatattga ttatagagga attagaggga
     2881 ggtgtacggg tggacaatga ctggaatgga ttggctgatt tgatagcaaa tcttattaca
     2941 aagtatgctg gtgttttaga tttggataat ctaccagatc caatgccagt aaataataac
     3001 agtgaaaatg aaaatatctt tgacatggta aaaacacaga ttgagaaaat gaaataaaag
     3061 tgctataata tacttgagat ataagtccaa actttttgga agtatgaaaa agatatagag
     3121 aaatatattg aggttaatgc tatgtcaaaa gagaaaataa aagtatacct ctacacaaga
     3181 gtatctacat caatacagat agatggttat tctttagagg cacaaaaatc aagaatgaag
     3241 gcttttgccc tttataatga ctatgaaatt gttggtgagt atgaagacgc aggtaagtct
     3301 ggaaaatcta ttgagggaag gatacagttt aatcgaatga tggaagatat aaaatctggc
     3361 aaagatggag tatcttttgt tcttgtgttt aagctatcaa gatttgcaag aaatgctgcg
     3421 gatgttttat caacattaca aacaatgcaa gattttggag tcaatttgat ttgcgttgag
     3481 gatgggattg attcatccaa agatgcaggt aaattgatga tttctgtttt atcagctgtg
     3541 gctgaaattg aaagagaaaa tattcgtgtt caaacaatgg aagggcgtat tcaaaaggca
     3601 agagaaggga aatggaatgg aggttttgct ccttatgggt atcagcttgt cgatggtaaa
     3661 ctgtttatca atgaagaaga agctgtcgca ataagaacta tttttgatca atatgttaat
     3721 acaaccattg gagctaatgg actttcaaaa tacttagaaa atcatggaat aagaaaaatt
     3781 ccaagacaga atggaaaaaa tccattgttc gatgcaggtc ttataagaaa gatattaaag
     3841 aatcctgtat ataacgggaa gatagctttt ggaagaagaa ctttagaaaa agttcatggt
     3901 acaagaaatg aatataaaca agtagaacaa gatgaatatt taatagctga aggaattcat
     3961 gaagctataa tttctgatga gttatggcag gctgctcagg ttaagctaaa atctcaagca
     4021 aagaaatatg agcatgtgaa taaaggaaaa gatatacgta cacacttact ttcaggaatt
     4081 gtaaaatgcc cggtatgtgg agtgggaatg tttggcaaca agtgtatcaa gaaaaggaaa
     4141 gatggtacaa agtataaaga tttttattac tatggctgta aacataggca gatgatgaga
     4201 ggtcataagt gtactttcag taagcaaatt agagaggaat tgttagatga tgcagttgct
     4261 gaggtaatta taaagatagt aagcaatccc aaatttgctt ctatgatgca agaaaaaatc
     4321 aatatgaaag tggatacctc tgaaatagaa aaggaaatag ataattatca aaaagaactg
     4381 cggaaaagtc attccacaaa gtttaagcta attgaggaaa tagataattt agatgctgat
     4441 gataagcact acaaacgaag aaaacaggac ttagacgata gactttatcg tatgtacgat
     4501 aaaattgaag aattagaatc attcttaatt gatgcgaaag caaaaaaaca aactattgaa
     4561 gctgaaaaac ttacaggaga taatatatat aaagttctga tctattttga taaactctac
     4621 aaggtaatga atgatgtgga gcgtagacag ttaattacag ctttgatttc tgaaattcaa
     4681 atttacgaag aaaagcaacc gaatggacaa tggctaaaat caattacttt taaacttcct
     4741 atcatcgatg aagatttaaa tataggtttg gacaatgatg aacaagttga gtgtgttgct
     4801 ctgctcgtaa aagcctagaa acctttgaac gaaagggata gtaaaatgcc ttgatatcag
     4861 ggcttttttg ttatgtaaag ggaagtatca gagtgagagt taagattgaa tgagtaggtt
     4921 tgatagtttg atgtttgagt gatttatttc cataaaccct agggggtacg gagttatttc
     4981 catatact
//
LOCUS       DARYSY010000088         4787 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYSY010000088 DARYSY010000000
VERSION     DARYSY010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4787
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..201
                     /locus_tag="TVR04_001845"
     CDS             <1..201
                     /locus_tag="TVR04_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270511.1"
                     /translation="ELTMDKKNYIEAICETMYDESNEWYEDIYDMSPYDIAELFEKTV
                     KEEVGITVTFKAIDLEVSILED"
     gene            392..706
                     /locus_tag="TVR04_001846"
     CDS             392..706
                     /locus_tag="TVR04_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1270512.1"
                     /translation="MDREMININANLVKEAEFSEFEKDGESIQVANFALVKKYGKGKE
                     YTNCSVYGEKVEIAKEFEKGDLIHVFGYFKENKKGDKVYKNFIVKSLNKIENKEKENE
                     EE"
     gene            708..923
                     /locus_tag="TVR04_001847"
     CDS             708..923
                     /locus_tag="TVR04_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1270513.1"
                     /translation="MEFFTAGVGVLKTLVTAIGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGIKLIPLLANALN"
     gene            934..1797
                     /locus_tag="TVR04_001848"
     CDS             934..1797
                     /locus_tag="TVR04_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270514.1"
                     /translation="MFGIFDKLTEFFKDMLLGGIKANLESMFLDINDKVGVIATDVGK
                     TPMGWNGEVYNFIKNINDNVIVPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMFIAVYLASHAFEFSMAVFDVAQNLVNKAAGVITTSATVSGDQIVAMVDTLKEKD
                     VGALIMVLVETSLVRIAIQCISLTITLIVYGRMFEIYVYSSVSSIPFATMGNKEWGQI
                     GTNYIKGLFALGLQGLFLMVCLGIYTVLIRTVQVTDIHASLFSILGYALLLGLMMFKS
                     GTVAKSIMNTH"
     gene            1807..2097
                     /locus_tag="TVR04_001849"
     CDS             1807..2097
                     /locus_tag="TVR04_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270515.1"
                     /translation="MLKKKNCVLLGLGILLGGTYEFLKEKKRNEEIRNLKKRINRLGR
                     CHNEFVMYQGEYNDRNEEKQEELEERISYLEEETTSNYDHILELSKEEVEGD"
     gene            2099..2509
                     /locus_tag="TVR04_001850"
     CDS             2099..2509
                     /locus_tag="TVR04_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1270516.1"
                     /translation="MAYVPIPKDLDKIKTKVAFNLTKRQLIGFSVAGLIGIPTYLFMK
                     KYLPNDVSIIVMLIVTLPIFFITLYEKDTLTFEKYFKFFYLHKFYQPTKRIRKEAYLE
                     AKKKANQRLKSKGKTIKKRPQGSKKAKSKERSNK"
     gene            2400..>4787
                     /locus_tag="TVR04_001851"
     CDS             2400..>4787
                     /locus_tag="TVR04_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1270517.1"
                     /translation="MKQRKKQISDLNLREKQLKKDRKEVRRLKAKKDPTNSLLSVLLK
                     KEKKRFTVEDTIPYIRMLPEGICQLDEKNYSKTISFQDINYQLALEEDRDLIFNQFAN
                     FLNSFDPSVHIELSYVNQLGRNKDLQDAIKIADKGDFYDDVRKEFREMLKLQLAKGNN
                     GLKKMKYITFTTEADNLEQARAKLNRLEVDILSNFKSMGVRAESLDGEERLRLVHDML
                     NPDKNFDFSYKDLKKKESTKSHITPNIFNFAPANNFKFGKYIGAVSHFQILASELSDR
                     MLSEFLDIDDNIYVAFHIDVVEQAEAIKLIKRKNTDLDRMKIEEQKKAVRAGYDMDII
                     PSDINTFGADVKSMLSDLQNRDERLFVVTIVMMNFARTNQKLENTIAQISSIANRHNC
                     QVKRLSHQQEQGLVSVLPLGVNQVEIKRFLTSSSTAVFMPFTTEELFIDSANSLYYGL
                     NALSQNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEGEY
                     SNLVKQFNGEVIKVSAKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGSGL
                     TAAEKSVIDRCLPKIYQKYFEDPKPENMPILGDLYDMLLSQEEGVGRKLATEMEIYVK
                     GSLNVFNNRSNVDLNRQLLCFDIKELGTQLKKIGMLVIQDQVWNKVSLNRGSKSTRYY
                     IDEFHLLLKDPQTASYSVEIWKRFRKWGGIPTGITQNVKDLLTSQEIENIFDNTDFVL
                     MLNQASGDRDILAKKLKISPYQLNYITNSNAGEGLLFFGNTIVPFIDKFPKDTMLY"
BASE COUNT         1850 a          624 c          905 g         1408 t
ORIGIN      
        1 gaactcacaa tggataagaa aaattatatt gaagcaatat gtgagacaat gtacgatgaa
       61 agtaatgaat ggtatgaaga tatatacgat atgtctccat atgatatagc tgagctattt
      121 gagaaaacgg taaaggaaga agtaggaata actgttacat ttaaagcgat agaccttgaa
      181 gtatcgattt tagaagatta gaaataaggt attaataggc gatagaaatt aaaaactcta
      241 tcgtcttttt ttatactcaa aattaggagg ttaagatggt aaggataaga agtcccactt
      301 aaaacaattt aatatataag acacttagcg attgaaatat aagttcagtc gcttttttaa
      361 ttgaaatttt tagattaagg agaagaaatt aatggatagg gaaatgataa atataaatgc
      421 aaatttagtt aaggaagctg aattttcaga atttgaaaaa gatggagaaa gtattcaagt
      481 agcaaatttt gctcttgtta aaaaatatgg aaagggcaaa gaatatacaa attgctcagt
      541 atatggagaa aaggtagaaa ttgcaaaaga atttgaaaaa ggagatctaa tccatgtctt
      601 tggatatttc aaagaaaaca aaaaaggaga taaggtctac aagaacttta tagttaaatc
      661 actaaataaa atagaaaaca aagagaaaga aaacgaggag gaataatatg gaatttttta
      721 cagctggagt tggagtttta aagacacttg taactgcaat tggtgcaggt ttaggagcat
      781 ggggagttat taacttgatg gaaggttatg gtaatgataa ccctggtgct aaatctcaag
      841 gtattaagca gcttatggct ggtggaggaa ttgtactaat cggtattaaa ttaattccac
      901 tacttgcaaa tgctttaaat taggagaaag tctatgtttg gtatctttga caagctaact
      961 gaatttttta aggatatgct actcggaggt atcaaagcaa atcttgagtc catgttctta
     1021 gatataaatg acaaggtagg agttattgca actgatgttg ggaaaacacc aatgggttgg
     1081 aatggagaag tatataactt cataaaaaac attaatgata atgtgattgt tccaatagca
     1141 ggtcttatca taacagcagt tttatgtatt gaactcataa atatggttat gcaaaagaat
     1201 aatatgcacg atacagatac ttttgagttt ttcaaataca tcataaagat gtttatagca
     1261 gtctaccttg caagccatgc ctttgaattt tcaatggcag tctttgatgt ggcacaaaat
     1321 cttgtaaaca aagcggcagg ggtaatcact acttctgcca ctgtttcagg agatcagata
     1381 gttgcaatgg ttgatacgct gaaagaaaaa gatgttggtg cattaataat ggtattagtt
     1441 gaaacaagcc ttgtaaggat tgcaattcaa tgtatatctt taactattac cttaatagta
     1501 tatgggcgta tgtttgaaat atatgtctac tcatcagtat catccatacc atttgcgact
     1561 atgggaaata aagaatgggg tcagattgga acaaattata tcaagggact ttttgctttg
     1621 ggactacaag gtttgttttt gatggtatgt ttaggtatct acaccgtttt aataagaacg
     1681 gtacaggtta cagatattca cgcaagcttg tttagtatat taggatatgc tctactactt
     1741 ggacttatga tgtttaagag tggaacagtt gcaaaaagta ttatgaatac gcactaggag
     1801 gaataaatgt taaaaaagaa aaattgtgtt ttattgggac ttggaatttt attgggagga
     1861 acttatgaat tcttaaaaga gaagaaaaga aatgaagaaa ttagaaactt aaagaaaaga
     1921 ataaatagac tcggaagatg tcacaatgaa tttgttatgt atcaaggaga atacaatgac
     1981 agaaatgaag aaaaacaaga agaattagaa gaaagaatta gctacctaga agaagaaaca
     2041 acatcaaatt atgaccatat acttgaactt tccaaagaag aagtagaggg agattaaaat
     2101 ggcatatgta ccaataccaa aagatttaga caagattaaa acaaaggttg cctttaactt
     2161 aactaaaaga caacttatag gtttttctgt ggcaggacta attggcatac caacctattt
     2221 atttatgaag aaatatctgc ctaatgatgt ttctattatt gtaatgctaa tagtaaccct
     2281 gccaatcttt tttataacct tatatgaaaa agacacctta acttttgaaa agtattttaa
     2341 atttttctat cttcataagt tttatcaacc aactaagaga ataagaaagg aggcatacct
     2401 tgaagcaaag aaaaaagcaa atcagcgact taaatctaag ggaaaaacaa ttaaaaaaag
     2461 accgcaagga agtaagaagg ctaaaagcaa agaaagatcc aacaaatagt cttctaagtg
     2521 tacttttaaa gaaagagaaa aagagattta cagttgagga tactattccc tatataagaa
     2581 tgttaccaga gggcatttgc cagttagatg aaaaaaatta ttcaaagaca atttcatttc
     2641 aagatataaa ttaccagttg gcattggaag aagatagaga tttaatcttt aaccaatttg
     2701 ccaacttttt aaattctttt gatccaagtg tccacattga actttcatat gtaaatcaat
     2761 taggaagaaa taaagaccta caagatgcaa ttaaaattgc tgataaggga gacttctatg
     2821 acgatgtaag aaaagagttt agggagatgt taaagcttca acttgcaaag gggaataacg
     2881 gacttaaaaa gatgaagtat ataaccttta ccacagaagc cgataaccta gagcaagcaa
     2941 gagcaaagtt aaatagactt gaagtagata ttttatctaa ctttaaatct atgggagtaa
     3001 gagcagagag tcttgatggc gaagaaagac taagacttgt tcacgatatg ttaaatccag
     3061 acaaaaactt tgatttttca tataaagatt tgaagaagaa agagtctaca aagtcacata
     3121 taactcccaa tatctttaac tttgcaccag caaataattt taaatttggt aaatatattg
     3181 gagcagtaag ccattttcaa atactagcaa gcgagttatc agacagaatg ttatctgagt
     3241 ttttagatat tgatgataat atttatgtag cttttcatat agatgtagtt gaacaagcag
     3301 aagccattaa actcattaag agaaaaaaca cagacctgga tagaatgaaa attgaagaac
     3361 aaaagaaagc agttcgtgct ggatatgata tggatattat tccttcagat ataaatactt
     3421 ttggggctga tgttaagtcc atgttatctg acttacaaaa tagagatgaa aggctctttg
     3481 tagttaccat agtaatgatg aattttgcta gaactaatca aaaattagaa aatacaattg
     3541 ctcaaatttc atcaattgca aacagacata attgtcaggt aaaaagatta tcccatcaac
     3601 aagaacaggg acttgtttct gtcttacctc taggagttaa tcaagttgaa ataaaaagat
     3661 ttttaacttc atcatcaacg gcagttttta tgccttttac aacagaagag ttatttattg
     3721 attcggcaaa ttctttgtac tatggcttaa atgcccttag ccaaaacttg attatggcag
     3781 ataggaagaa actgaagaac cctaacggac taatattagg aacaccaggt tctggtaaat
     3841 ctttctcagc aaagagagag atggcaaatg caattctagt aacagacgat gatgtaatta
     3901 tttgtgatcc tgaaggcgag tattcaaacc ttgtaaaaca atttaatgga gaagttatta
     3961 aagtttcggc aaaatcaaag gactacctaa atccattaga tattaatatg aactatggag
     4021 atggggacgc acctttaaaa gataaggcaa atttcataat gtctatgctt gaacttgtag
     4081 taggaggatc tggtcttact gctgcagaaa aatctgttat agataggtgc ttaccaaaga
     4141 tataccaaaa atattttgaa gacccaaaac cagaaaatat gccaatatta ggggatttat
     4201 acgatatgct cctatctcaa gaagagggag ttggtaggaa gctcgcaaca gaaatggaaa
     4261 tttatgttaa gggcagtctt aatgtcttta ataataggtc aaatgttgac ttaaataggc
     4321 aattgctctg ctttgatata aaagagctag gaacacaact taaaaaaata ggtatgcttg
     4381 taattcaaga ccaggtttgg aacaaggttt ccctaaatag aggaagcaag tctacaagat
     4441 actatataga tgagttccac cttttattaa aagaccccca aactgcttca tattcagtag
     4501 aaatctggaa aagatttaga aaatggggag gtattccaac aggtataaca caaaacgtaa
     4561 aagacctttt aacaagtcaa gaaattgaaa atatctttga taatacagac tttgttctaa
     4621 tgttaaatca agcatctgga gatagggata ttcttgctaa aaaattaaaa atatcgcctt
     4681 atcagttaaa ctatattact aattcaaacg caggtgaggg attactattc tttggaaata
     4741 ctattgttcc atttatagat aaattcccta aagacaccat gctatat
//
LOCUS       DARYSY010000089         4667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYSY010000089 DARYSY010000000
VERSION     DARYSY010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4667
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..860
                     /locus_tag="TVR04_001852"
     CDS             <1..860
                     /locus_tag="TVR04_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270518.1"
                     /translation="LNKGQTIDLSEVFDEVTKMYKETPNERYTFEIAGDKYKLERLKQ
                     PNDLEPYYHLVVEELRDFNFPSKTKLFGESQELGLADDEFLGEKMSALYDYENAVFML
                     QVNRNSISTNKFESFLSSLLEELGYSGCDIRLPIIIQADAERVAKSFTGYKHVAIKMD
                     EKSSPSDNFDLIEIIKNAISSSKDSNLFDVEISLTAKKDTGSTGEYLPDSIVNEIMSI
                     NRNGVKKLHVKGRNLDEKIETVDLISNKLMEVIHFQYDENRTLNPASVFSEMSVRYTE
                     VKNKVLRNK"
     gene            857..1342
                     /locus_tag="TVR04_001853"
     CDS             857..1342
                     /locus_tag="TVR04_001853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270519.1"
                     /translation="MKVIKQNRFWLVYGISAILIILVSISLSSCFVKLKINDFVGDVL
                     NFSSIMTGFLGAMLGILASISKSTAIMKTVFETTRAKLQLILSIIVPFAVGMVNIIVC
                     AFYRLFLLNNLDVKILSVFFWSSTLFFLVSSILMVVLIFIFYFFENDEINNTMMKPQK
                     K"
     gene            complement(1700..2917)
                     /locus_tag="TVR04_001854"
     CDS             complement(1700..2917)
                     /locus_tag="TVR04_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1270520.1"
                     /translation="MTITKTKNGTYRLKVYIPTEARMPLGIVNNNYFDKRFKTRKEAR
                     QAEIDLLTKLNQIENNEFTGLGKGEILFKDFYENIWWNPYKSGQTTSTSKPPTRSTVA
                     NTKTCFEKHILPLLGNYTIQFLNQNKQVILNLMTAKANEYANFKTLRSYVISIFDWAE
                     ELEYIEANRIAKTLRRIKSTKKIQLAEARKDEDLYLTQEQLQAWFTAFKQDLDDDKIS
                     LKDYVLFYLTFFLGDRKSETYALQWKHIDFSTSQIQLIQALDRYGEVKSTKGNKKTIF
                     SISNDLVQLLNSWKEQQKQELARFGIISNPEQFVFTYIDTKGNVNARLHPDYLNNKMK
                     TVRNRHKELAHATPHKLRHTGATLAKQAGMSLEAISEALTHSDTATTQIYVNTSNVVP
                     MAVGEFALKSLKQ"
     gene            complement(2983..3246)
                     /locus_tag="TVR04_001855"
     CDS             complement(2983..3246)
                     /locus_tag="TVR04_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1270521.1"
                     /translation="MQVILPNEQIQQIQLLLSNLIKREIEEQLSRNGIESPYLNKQQA
                     CNYLGISNNTLDSWIQQGLPYIKIGKSIRFNKQSIDTWLLSQN"
     gene            complement(3248..3853)
                     /locus_tag="TVR04_001856"
     CDS             complement(3248..3853)
                     /locus_tag="TVR04_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004049121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEL1270522.1"
                     /translation="MAKEQQKRSTIWTFLIYKESAPEDYKQVLEELCIPFVLSPWHDK
                     DIDRKTGEFKKPHKHGAFFFDSLKSYRQVSELIKNKLNGPEHVEIVMSPTGLYHYFTH
                     AENPEKSPYNIDDIESGCGFDLDKFLLERNSSEFINEVVDIIEENDFTEFEELVWYSR
                     ANNSMLLNLILERTYFFAKYLDSRRHNPNRLNNSKQISEEE"
     gene            complement(3994..4611)
                     /locus_tag="TVR04_001857"
     CDS             complement(3994..4611)
                     /locus_tag="TVR04_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270523.1"
                     /translation="MKKSFFQKTYNLNINLIILILLLLLLKFALLLLENQLGNIEIES
                     LQSSISFVQDKLNFIAYFVQSLTLTLTSILVLSICTELFQRFTKDSILNYFKSIYQTI
                     RLRQFLKQDEMSESIISIDNQTTVTKFNPILKNFNHAISSCTVDIRQNTLSVFIKYPR
                     TQQAQKLLRDMEGHVKEEISGQNPNYYFSSSIREGNKLWYIGTRR"
BASE COUNT         1441 a          671 c          883 g         1672 t
ORIGIN      
        1 ttttgaataa gggacagaca attgatttat ctgaagtttt tgatgaagtt actaaaatgt
       61 ataaagaaac accaaatgaa agatatacat ttgaaattgc tggagataag tataaattag
      121 agcggttaaa gcaacctaat gacttagaac cttattatca tctagttgta gaagagttaa
      181 gggatttcaa tttcccaagt aaaacgaagt tgtttgggga atcccaagaa ttaggattgg
      241 ctgatgatga gtttttagga gaaaagatgt cagctttata tgattatgaa aatgcggtgt
      301 ttatgcttca agtaaaccga aattcaatca gcaccaataa gtttgaatct tttttaagtt
      361 ctttgctaga agaattaggg tattctggtt gtgatataag acttccgatt attatacaag
      421 cagatgcaga aagagttgca aagagtttca cagggtataa acatgtagct atcaaaatgg
      481 atgaaaagag ttctccgagt gataattttg atttaataga aattataaaa aatgctatat
      541 cttcaagtaa agattcaaac ttatttgatg tagaaatttc attgactgcc aaaaaagata
      601 caggtagtac aggagagtat ttaccagaca gcattgttaa cgagattatg tctattaata
      661 gaaatggggt caaaaaatta catgttaaag gacgaaatct tgatgaaaaa attgagacag
      721 ttgatttgat ttcaaataaa ttgatggaag taattcattt tcagtatgat gagaatagaa
      781 ctttgaatcc agcttcagta ttttctgaaa tgtcagtgag atatacagaa gtaaagaata
      841 aggttttaag aaataaatga aagttataaa acaaaataga ttttggcttg tctatggtat
      901 aagtgcaata ttaattatcc tagttagtat ttctctttcc agttgttttg taaaattgaa
      961 gataaatgat tttgtcggag acgtacttaa cttttcttca ataatgactg gctttttagg
     1021 agctatgtta ggtatacttg cgtcaatctc caaatctaca gcgattatga aaacagtatt
     1081 tgagacaaca agagcaaagt tacaattaat actttcaatt atagttccat ttgctgttgg
     1141 tatggtaaat attattgtat gtgcttttta tagattgttc ttattaaata atctagatgt
     1201 taagatactg agtgttttct tttggtcatc aacattgttt ttcctagttt cgagtattct
     1261 gatggttgtt ctgattttta ttttttactt ttttgaaaat gatgaaataa acaatacgat
     1321 gatgaaacca caaaaaaaat aaaaacgcag gctgggttga gcctgcgttt tggattccac
     1381 aaattttaga aaagactacg ctatttcaaa aatttttatg aatgagaata aatgactagt
     1441 ctattttgtg gtgttaattg gtgtcaattt tatccaaatt tatggatttt agtccatttt
     1501 catggaagtt tcaaactgta agatgttgat ataaagggat ttataaggga tgagtatcct
     1561 tagttttcaa tggggaagtt ctcaaaacgt taatatcagc gatatatcaa cgtttcaagg
     1621 cactcaagag tttacctcat gggtgctttt ttcgttgttt tttggaaaag ttcacctcaa
     1681 aatttacctt attttcacct tattgtttta gagacttcaa ggcaaattcg ccaactgcca
     1741 taggaacgac attagaagta ttgacataaa tttgagttgt ggcagtgtcg ctatgtgtca
     1801 gagcctcaga aatggcttct aagctcattc ctgcttgttt agcgagtgtt gcccctgtat
     1861 gtcttaactt gtgaggtgtg gcgtgtgcga gctctttatg acgatttctg acggtcttca
     1921 ttttattatt taagtagtca ggatgtagac gtgcgttaac attacctttg gtatcaatat
     1981 aggtaaaaac aaactgttca ggattactaa taattccaaa cctagccagt tcctgttttt
     2041 gttgttcttt ccatgagttg agaagttgaa ctaagtcatt tgaaattgaa aatatcgttt
     2101 tcttatttcc tttggttgat ttaacttccc catatctatc tagagcttga atcagttgga
     2161 tttgtgaggt tgaaaaatca atgtgtttcc attgtaaagc ataagtttcc gatttcctat
     2221 ctcctagaaa aaaggtcaaa tagaagagga catagtcttt taacgagatt ttatcatcat
     2281 ccaaatcttg cttgaacgca gtaaaccatg cttgtaattg ttcctgagta agatagaggt
     2341 cttcatcttt tcgagcctct gctaattgga ttttctttgt tgacttgata cggcgtaagg
     2401 tttttgcgat acgattagct tcaatatatt caagttcttc tgcccagtcg aatattgaaa
     2461 taacgtaact tctgagagtt ttgaagttag cgtattcatt cgccttagca gtcattaagt
     2521 tcagaataac ttgcttgttc tgattgagaa attgaattgt atagttacct agcaaaggta
     2581 aaatgtgctt ttcaaagcaa gttttagtat tggcaacagt tgaccgagtt ggtggtttag
     2641 aagttgaggt tgtttgtcct gatttgtagg ggttccacca aatattttca tagaaatctt
     2701 tgaataatat ttccccttta ccaagccctg taaattcgtt attttcaatc tgatttagtt
     2761 ttgttaaaag gtctatctct gcttgtctag cctcctttct tgtcttgaac cgcttgtcaa
     2821 agtagttgtt attcacgata ccgagtggca ttcgtgcttc agttggaatg tagactttta
     2881 ggcggtaagt tccgtttttt gtcttagtga tagtcatgat attctccttt aggtcgaacc
     2941 agaaaatatc atgaccatta taaaacaaaa ttgtagatat ttctagtttt gtgaaagtag
     3001 ccaagtatct atagattgct tgttaaagcg gatagattta cctattttta tgtaaggaag
     3061 tccttgctga atccagctat ctaatgtgtt gttggagata ccgagataat tacaagcttg
     3121 ttgtttgttt agataggggc tttcaatacc gtttcttgac aactgctctt caatttctct
     3181 cttaataaga tttgaaagta gaagctgaat ctgttggatt tgttcatttg gtaggataac
     3241 ttgcatatta ctcctcctca gaaatttgtt tagaattatt taaacgatta gggttgtgcc
     3301 gtctagagtc aaggtattta gcgaaaaaat aagtacgttc aagtatcaga tttaatagca
     3361 tactattatt ggctcgtgag taccaaacaa gttcttcaaa ttcggtaaaa tcattttctt
     3421 cgataatatc aacaacttca ttgatgaatt ctgatgagtt tctttccaat aagaatttat
     3481 ctaaatcaaa accacaacca gactcaatat cgtcaatatt gtaaggtgat ttttctggat
     3541 tttctgcatg tgtgaaatag tgatatagac cagttgggga catgactatt tctacatgtt
     3601 caggaccgtt taacttattt ttgataagtt ctgatacttg tctataactt tttaatgaat
     3661 caaagaagaa agctccgtgt ttgtgaggtt tcttgaattc tccagttttc ctatcaatat
     3721 ccttatcatg ccacggacta agtacgaaag ggatacaaag ttcttctaat acttgtttat
     3781 aatcttctgg agcgctttcc ttataaatta ggaaagtcca gattgttgag cgcttttgtt
     3841 gttcttttgc catgcattac acctcattat tttgattact gattattgat tgtaatgggg
     3901 gtcgtagtag cccccattac atcgtgtgat tagataccct gaagaagcag agcttttggc
     3961 tttcactacg tgagccaagc cccgcttctt cttttatcgt cttgtgccta tgtaccagag
     4021 tttatttcct tccctgattg aagaagagaa ataatagtta ggattttgtc cagagatttc
     4081 ttctttaaca tgtccttcca tatctcgtaa aagtttttga gcttgttggg ttcggggata
     4141 tttgataaag actgacaagg tattttgccg aatatctacg gtacagctag agatagcgtg
     4201 attgaagttt ttaagaatcg gattgaactt tgtaacagtt gtctgattat caatagagat
     4261 aattgattcc gacatttcat cttgtttcaa aaactgtctt aatcgaattg tttgatagat
     4321 ggatttaaaa tagttcaaaa tagaatcctt tgtaaagcgt tgaaatagtt ctgtgcaaat
     4381 cgacagcacc aaaatcgatg ttagagtcag agttaatgat tggacaaaat atgctataaa
     4441 atttaattta tcttgtacaa aacttataga actctgtaga ctttctatct caatatttcc
     4501 aagctgattt tctagaagta gaagtgcaaa tttgagaaga agtaagagca aaatcaggat
     4561 gatgagattg atattcagat tgtaagtctt ttgaaaaaaa ctctttttca tgtcataaaa
     4621 tacctttctt ggtgtagtat gtagggcaaa gtaacggaag aactgaa
//
LOCUS       DARYSY010000090         4571 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYSY010000090 DARYSY010000000
VERSION     DARYSY010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4571
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            166..1386
                     /locus_tag="TVR04_001858"
     CDS             166..1386
                     /locus_tag="TVR04_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1270524.1"
                     /translation="MKTKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLNQTEKENYLLLYDSLSAFHEVTSLAPASKHSLMKTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDAFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISFINQQ"
     gene            complement(1496..1990)
                     /locus_tag="TVR04_001859"
     CDS             complement(1496..1990)
                     /locus_tag="TVR04_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1270525.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEAGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKV"
     gene            complement(1987..2769)
                     /locus_tag="TVR04_001860"
     CDS             complement(1987..2769)
                     /locus_tag="TVR04_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1270526.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDGVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHIPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLESLSQ"
     gene            complement(2868..3407)
                     /locus_tag="TVR04_001861"
     CDS             complement(2868..3407)
                     /locus_tag="TVR04_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1270527.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(3411..3722)
                     /locus_tag="TVR04_001862"
     CDS             complement(3411..3722)
                     /locus_tag="TVR04_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270528.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTNHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPACHKHQDIYFSKE
                     L"
     gene            complement(4110..4247)
                     /locus_tag="TVR04_001863"
     CDS             complement(4110..4247)
                     /locus_tag="TVR04_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1270529.1"
                     /translation="MHQNPTERSDLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
BASE COUNT         1402 a         1092 c          904 g         1173 t
ORIGIN      
        1 aaaaaacgtc tcacatctgg ctcataaagc ttaattagct caacagtagg cctagccaag
       61 ctgatcaaaa caaacaagca aacgctatca ataagaccat accttaaagc caagctcgat
      121 tagacttgtg ctataatggt accaacaaac ctgagtggag ataatatgaa aaccaagctt
      181 agcctattcc tgctagcagc actgactata gtcggtctct cagcctgtgc atggagatcc
      241 aatcctcttg ctgacaagga gcagcagttc ggcctgactg gagcaagacg tcagcaggtg
      301 cttgatcaga tcgatcaacg ttattattac cagcagctta atcagacaga aaaggaaaat
      361 taccttctct tgtatgatag cctctcagcc tttcacgagg tgactagcct agcaccagct
      421 tctaagcata gcttgatgaa aaccattgat gcctttatga tggataatcc tgcctttttc
      481 tggattacct cagccaacta tcgcttggaa cgctcagatc aggtggcctt cgttaccttt
      541 ccattgccag agaaggtcga acaaacctat cacaggcttc aagccattgg agatgatatc
      601 atcgctgaca tgccagcaac caatgactat gagcgcgtga ggtattttta tgagtggatc
      661 atcaagcaaa ctgactacaa tagagatgcc tttgaggcat atcaatcggg tcatgaggcc
      721 ttgatagcct ctaatcaaga cattcgcagt gtctttcttg atcatctttc tgtctgcaac
      781 ggctatgcac aggcctttca gtttctttgc caaaaggccg gtattcctgt cgcctatatt
      841 cgagggtcag tcacctttga tcgatcacag gacgctttta ctcatgcttg gaatactgtt
      901 cagattgcag gcaagaacta tgctgttgac acaacctttg gagatcccgt ctttgatcaa
      961 aacgaatcca ttaaacaact agaggttaat tataactttt tatgcttgcc agaccagctc
     1021 atgaagcagt cgcatcaagc cagcagggat attgtgatca atcagacaga aaccttgacc
     1081 gatgtctgga caattcctga gtgctcagac gattctctgc tctataccaa gctcaatcac
     1141 agctacttta ctgcctttga tagaccagac attctggcca gtcttgagca gcaattaagg
     1201 actaatcaac cacagaccag cttacaattt gctaatcagg acctctacaa ccaaatggta
     1261 agtgatcttg agcagcattc tgacagctac catagcctgt ttcaagctta ttggcctaat
     1321 gctgctggct atttctacag tctacacccc agcaccttta gcattagctt tatcaatcag
     1381 caatagccta ataccctgac agacaagcac aagcgcttat ggcatggctc taccagccat
     1441 taaagagctg tgctaggctc tcaaggggct tttttcttgc taatcgctca atgggctaaa
     1501 ccttactttc cttatcctgc tttttctggt cacgcctttg ccggaaaaag gtctgcatga
     1561 gcttggcaca gtcatcagct aaaagacctg cctcaagctg tacacgatgg ttcaggcgct
     1621 catcggttaa gatctgataa agactaccag caccgccaaa cttttgattg ctggccccat
     1681 agaccacatg aggaattcga gctagcccaa tggctccgct gcacatgaca caaggctcaa
     1741 tcgtcacaaa aagagtcgta tccaagagac gccaattgcc ttcgtgcgca ttggcttcat
     1801 taatggccat gatctcagca tgcataatcg cctgattgcg ctcctcgcga gcattgtgac
     1861 cacgcccgat aatgtgacca gccttcacaa taacgcagcc aatcggtatc tcgtccttta
     1921 gcagcgattt ctcagcctct ttgagggctt ctcgcataaa atactcttgc tcttgtttgg
     1981 aatagctcat tgagatagac tctccaaatc ccaagcccga tgtggcagag caagatcaac
     2041 aggaatctga ccagcatagc cttgagcttg ctgtcgcagc acctccaaat gcctcttagg
     2101 atcaatcccc tctggcggca gaggtggtat atgagtcaag accaagcgtt tcaccttagc
     2161 acgactggca agctgaccag cctcttttga ggtcaaatgc gccatatgat gttcattgcc
     2221 ttcataaagg tacacatctg ctaaaaacac atcagcctcc gcagcaaaat cagctagttc
     2281 ttcaaagtag cctgtgtctc ctgtaaagac aagcacctgc ccagttgctc tttccacaat
     2341 acgaaacgca tagcacacga ccgggtgaac cgtcttaata aaggtaatgt caaaaggtcc
     2401 aagagcttca accccatcaa cctgataggc aatgcccttt gagacacctg gcagagttag
     2461 cttggcaaac tcggcctcat cttcgtcatg accgtaaata ggtagtagcc ttggcttgcc
     2521 aagatgcctt ggatagagct gataataatg acgcaaaaca cccaagtctg ccacatgatc
     2581 tgggtgataa tggctaatga taacagcgtc taaatccagc ggattgattt ctttttctaa
     2641 ttcgttaaga gaacgactac cagcatccat caataattga aaaccatcat gccctgtcac
     2701 aagataggct gtcgtcccag catcttgata gggataggct ccccaagagc caagcgttgt
     2761 taatttcatc acaaaacctt ccttcatgct ttgttcttat tataacaaaa aatagcagca
     2821 aaaaataagt cctagtgcgc aagagctagg acttacaggc ttggtattta gctgttggtg
     2881 tttaaaaagc tgtctttata gctaacagca agcgccgttg cgatgactgc cttaatagta
     2941 tctcccggga taaagacaag gctagcaacg agcgatctag tgagcggcat gtctgtataa
     3001 accgctaacc aaatagtccc caacagatcc accagcagga caccagaaat aaagattgct
     3061 aaaaaagcaa gagaccgata ccttgctagc cagctgcggt acaagaatgc aaaaaccagt
     3121 ggaacaaaga gccaggccaa aacatagcca gccgatggtc ccattaggac tggaacagtt
     3181 gttctagagc ctgaaaatac tggcaagaac agaccaatca ctagaaaaag caggatagac
     3241 agggttcctt ttttcccacc taaaatcaag ccagcaagca tgacccctaa gttttgcaaa
     3301 acaatcggca ctggaacaaa gcctagagga atcgctggaa taagacctaa aataatgatt
     3361 aaggtggtca tcattgctac cttcactaag tccttggttg acaacatatc tcataactcc
     3421 tttgaaaaat aaatatcctg atgcttatga caggctgggt taaaagggct aaaacaaaaa
     3481 ggacagctgc cgcactcata ttcggacctt ctcagcagtt gtcggcaatg accacaaatc
     3541 accggatagg tctccttgtg gtttgtcggc tcaaaagcat gatcttgaag cgtgtcatga
     3601 caatgataac aggcataata agcctgacat cgagcacact tcaagccgac aatatccagc
     3661 actgtgtgat aatgtacaca gcgatactcc tgatcaagcg cgataccaaa acagttcctc
     3721 atgtcttatc ctcttattaa aaggataaag cattcgtttt attttgtcaa cctatattta
     3781 ctaatagggt tactaatcac ataagaagaa caccaaaaaa gcataaagta gtccccatag
     3841 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     3901 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     3961 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     4021 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     4081 taatcgtcga cctaccaaag ttgagacggt tattttttat tgtttaatat gacgattgca
     4141 acaactaagc tgattaaggt aagtaagaaa ctaccaaaag caagcatgag ttgaagggcc
     4201 tcgtaagtag acaataaatc gctcctttct gttggatttt gatgcattgc ccataggcac
     4261 cacctacctt tcagaataag agccaccgcc ttaacttttc tgcaaagtca ttatatcata
     4321 atcacacaag aaagctaggc taatttaaca tagtctaaca tgattataaa agttccatta
     4381 ataagactca gctttaatca aacttgataa acaagctagc taaatacagt gtctcgtttg
     4441 actatttttc cctattggga tataatgaga atagaaaaag ggcagttgct ctaaacaaaa
     4501 ctaccctatg cagaaccgtt taagacggtg gcagactgtt agttaaaaat aaccgtcaac
     4561 tctaccaaag t
//
LOCUS       DARYSY010000091         4347 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYSY010000091 DARYSY010000000
VERSION     DARYSY010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..230
                     /locus_tag="TVR04_001864"
     CDS             <1..230
                     /locus_tag="TVR04_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270530.1"
                     /translation="PLFQTVFKTFLKDRDKIENALDLPYSNAKLEATNNLIKVIKRNA
                     FGFRNFENFKRRILIAINMKKEKTKLVLSRC"
     gene            complement(729..4214)
                     /locus_tag="TVR04_001865"
     CDS             complement(729..4214)
                     /locus_tag="TVR04_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HEL1270531.1"
                     /translation="MRQKRRLHKMLSLFLVSLLVFGTIAPAVKVFAEPIDTLTAEPAE
                     QAKLETNDNTDEVNTQKNETTVSSSEASTEPHVEISHEDKGNAVEANISDEEAFDGMQ
                     RTANGVTVTINAAKGVFPKGTTVKVTDVAKEDVKAIISNKAKHVKDVAAVDITFYHNG
                     QEIEPKGKVDVKLATQKEVAGEEHKVVHIKDNKEVEEISTSSSTNASFKADSFSIYVI
                     VGTDKPSEQPETGKPIEKPTRRYEFYSQGKVVNTQILKNGEKLLEPSIPSLMDNVFVN
                     WSNKDGSEFNGFGTINDISKKETVALYANYTKKLAIRFHNTVEKNIIVKVGEEGKKVK
                     TDDVFFEVSVGNYINGWSKTPDGTEPVGKEITVGDQDIDLYPLITGGHWLFFNGNENG
                     GNLITKPLEPQFVKEGAKPSKFIPERKGYDFAGWYEDKDCTKALDFNKTLSENKEIFA
                     KWTPKASSYTIRIWQQRCVNGQFVPDHYVLNHVKTVDGISDSSIIKADAEKLATNYVE
                     ELAKKGDRRNWYDYYHYDFNAAKTTIEHDKVRGDGSSIVNVYYDLHPYTFKYYLNSEN
                     DKLDINNYDLQLMVNGEPYSKDDFYIVNNVHLGEVIDDRRPDIIVKRKDEKVEERVRI
                     GWEADHGSNHHYYLFKSDWENKAHGVPPQLLVRETEPGFDMLNFYPLFSTGKMIKIVR
                     FDYFETLEKGIYEERREEEESSITAAFSFGNQTGFTRVPSDQSYSAKIKVKRPDGRIE
                     EVTIPDKKEQVDRQTFHNIYNRNSYELTFFNKDVVEKSYKGDQAILYGTNIHDKLYTP
                     KKPLDLSELYTFKGWANKKGDVYDLTKYKKMPAGNLVLYAKWGIKQVTVTFDSNGGTP
                     VDPQTINAGEAVPMPKAPTRDNFKFAGWVLPNGSPFNVNTRLTEDTRLIARWLDKSAI
                     TVEYDPGAGAKAPVDSNRYMDISNARVLEAPKTLPKDKFFRGWELDGVVYYPGQFMLL
                     NSQLAKKQPNGTYKVTLRAVYSDAAEKTKLIYHSNFGDHKIIEEDYINNSDVKILGIK
                     DLHFEREGYDFIGWNTKADGTGLSYKVGDDIRVDNDLPLPNELFAQWKKKASSSEGNH
                     KPNSTKPNRPIVPPTTNETKRPHVSTATKPMKHQNTILPKTGDETNLFFYAGLMFLSA
                     SLCLLLDMRYRKAAK"
BASE COUNT         1217 a          937 c          714 g         1479 t
ORIGIN      
        1 atcctctctt tcagaccgtt ttcaagacct ttttaaaaga cagagacaag attgagaacg
       61 cactggattt gccttattct aacgctaaac tggaggctac caataatctc atcaaagtca
      121 tcaagcgcaa tgcttttgga tttcggaact ttgaaaactt taaaagacgg attttgatcg
      181 ctatcaatat gaaaaaagag aagaccaaat tggtcctctc cagatgttag cttgtcaatt
      241 acccactaca gttgacatgg agccataaaa aaaaacactc ctgctggcaa tctagtaaac
      301 tagaatcagg agagtgtttc attatagccc aacaagcaaa agggatactt ggtagaacca
      361 aagctgattt gcattgagaa gattaaaacc attcaatctg tcacaataat tatggaaaca
      421 ttaggaattt aaaaacaagt atcagcttct atcaacctat ggggaaatag tctccctatg
      481 cctatcgggc catcataggc cctcttaaag aagaggtgag agcctcatcg accagcaaaa
      541 acagctatca tcgccttaaa ggaaaacgac gaatgttatc acaggtgtcc caagaaaatg
      601 ctacaagaga ggctcatcac agcatgagta acctttttta ttgtgtcgtt tttatatcat
      661 tttgatcctt attatctaaa ggaatttaac cttgcgtcag ctgttaaaat ttatctcaca
      721 gcatcattct actttgcagc ttttctatac ctcatatcca ataaaagaca taagcttgct
      781 gataagaaca ttagcccagc atagaagaac agattggtct catcgccagt ctttggtaag
      841 atggtatttt gatgcttcat cggtttggta gctgttgaaa catgcggacg cttggtttca
      901 tttgtagtcg gtggtactat cggacgattt ggcttagtgc tattaggctt atgattgcct
      961 tcactactgc ttgccttttt cttccactgt gcaaacaatt cattaggaag cggcaggtca
     1021 ttatctaccc taatatcatc acctaccttg tatgataacc ctgtgccatc tgccttggtg
     1081 ttccagccta taaagtcata gccttccctt tcaaaatgca gatccttaat acctaagatt
     1141 ttgacatcac tgttattgat atagtcttct tcaataatct tatgatcgcc aaaatttgaa
     1201 tggtaaataa gctttgtttt ttctgctgca tcgctataga ctgcacgtaa cgtaacctta
     1261 taagtaccgt ttggctgctt cttagcaagc tgtgagttta ataacataaa ttgtcctgga
     1321 taatacacca ctccatcaag ctcccagcct ctaaagaact tatcctttgg taatgttttt
     1381 ggtgcttcca atactctggc gttggaaata tccatgtatc tattgctatc aactggtgct
     1441 tttgctccag ctcctggatc atattcaacg gtaatggcgc tcttatccag ccatcttgca
     1501 attaaccttg tatcctcagt caatcgcgta ttaacgttaa atggtgagcc gtttggcaag
     1561 acccaacctg caaatttaaa gttatctcgt gttggggctt tcggcattgg tacagcctct
     1621 cctgcattta tggtttgagg atcaactggc gtcccaccat tactgtcaaa ggttacagtt
     1681 acctgtttaa tgccccattt ggcataaaga actagatttc ctgccggcat tttcttatac
     1741 ttagtcaaat cataaacgtc acctttttta tttgcccagc ctttaaaggt gtataattca
     1801 cttaaatcaa gtggcttttt gggtgtgtaa agcttatcgt gaatattagt tccataaaga
     1861 atagcctgat cacccttata tgatttttca accacgtcct tattaaagaa tgtcagctcg
     1921 taagagtttc tattataaat attgtggaaa gtttgacgat caacctgttc ttttttgtca
     1981 ggaatagtca cttcttcgat acgaccatca ggtcttttaa cctttatttt ggcagaatat
     2041 gattgatctg atggtactct tgtaaagcca gtttgatttc caaaagaaaa ggcagcggta
     2101 atagaactct cttcttcctc acgacgttct tcataaatcc ctttttccaa tgtttcaaag
     2161 tagtcaaacc ttacaatttt tatcattttt ccagtagaaa acagaggata aaagttcaac
     2221 atgtcaaaac caggttcagt ttcccttact aacaattgtg gcggaacacc atgtgcctta
     2281 ttttcccaat cagacttgaa caaataatag tggtgattgc taccatgatc tgcctcccag
     2341 ccaatgcgga ccctttcttc taccttttca tctttacgtt taacaataat atctggtctc
     2401 ctgtcatcta tcacttcacc cagatgaaca ttgttaacga tataaaaatc atctttagaa
     2461 tatggctcac cattaaccat caattgcaga tcatagttat tgatatctag tttatcattt
     2521 tcactgttca agtagtattt aaacgtataa gggtgtaaat cataataaac attgacaata
     2581 gagcttccat cacctcttac cttgtcatgt tctattgttg ttttagcagc attaaaatca
     2641 taatgatagt agtcatacca gtttcttcta tcaccttttt tcgctaattc ttcaacataa
     2701 ttggttgcta atttttcagc atcagccttt atgatagagc tatctgatat accatctacc
     2761 gttttgacat gattcaagac ataatgatct ggcacaaact gaccattaac acatcgttgt
     2821 tgccaaattc gtatcgtata gcttgatgcc tttggcgtcc attttgcaaa gatttctttg
     2881 ttttcagaaa gggttttatt aaaatcgagt gcttttgtac agtccttatc ctcataccag
     2941 ccggcaaagt catagccctt tctttccgga ataaacttac taggcttagc tccttccttt
     3001 acaaactgtg gctctagggg cttcgttata agattgccac cattttcatt tccattaaag
     3061 aaaagccaat ggccacctgt gatcaatggg tataaatcaa tatcctgatc ccctaccgtt
     3121 atttcctttc cgacaggctc tgtcccatca ggtgttttag accacccgtt gatatagttg
     3181 ccaacggaca cttcaaagaa aacatcgtct gttttgacct ttttgccctc ttcgcccacc
     3241 ttcacgatta tatttttttc aacggtatta tggaatctga tggctagctt ttttgtatag
     3301 ttagcatata aggctaccgt ttcttttttg ctaatatcat tgatggtacc aaagccatta
     3361 aactcactac cgtctttatt actccagtta acaaaaacat tgtccattag gcttggaatt
     3421 gatggctcaa gtaatttttc accgttttta aggatttgag tattaacgac cttaccctga
     3481 ctgtaaaact cataccttct ggttggtttt tctatcggct tacctgtttc tggttgttca
     3541 ctaggcttat ctgttccaac gatgacatag attgaaaagc tgtcagcctt aaagcttgca
     3601 ttagtcgagc ttgatgtgct aatctcttca acttccttgt tatccttgat atgaacaacc
     3661 ttatgctcct cacctgctac ctccttttga gtagcaagct tgacatctac cttacccttt
     3721 ggttcaattt cttgtccatt gtggtaaaaa gtaatatcga ctgcagccac atccttaaca
     3781 tgcttcgcct tatttgaaat aatagcctta acatcttctt ttgctacatc tgtcacctta
     3841 actgttgtgc cttttggaaa aacaccctta gcagcattta tggttaccgt tacaccattg
     3901 gctgtccttt gcatgccatc gaatgcttct tcgtcagaga tattagcttc aacagcattg
     3961 cccttatcct catgcgatat ctctacatga ggttcagttg atgcttcact actacttacc
     4021 gtcgtttcat ttttctgcgt gtttacttca tcagtattat cattggtctc tagcttagct
     4081 tgttctgctg gctcagctgt taatgtgtct attggttcag caaagacctt aacagccggt
     4141 gctattgttc caaatacaag caaagaaact aaaaacaatg acaacatctt atgaagtctt
     4201 cttttttgtc tcatttaaca actccatttc acatatttta atgacaattg taaacaataa
     4261 tagactttac atgacacttt ctgatataat taaaaaagca attttatgat gtaaattgct
     4321 ttggtattaa tgacttttaa gcaatgt
//
LOCUS       DARYSY010000092         4131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYSY010000092 DARYSY010000000
VERSION     DARYSY010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4131
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(568..1308)
                     /locus_tag="TVR04_001866"
     CDS             complement(568..1308)
                     /locus_tag="TVR04_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1270532.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(1312..2610)
                     /locus_tag="TVR04_001867"
     CDS             complement(1312..2610)
                     /locus_tag="TVR04_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1270533.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDISLLMICHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFLKFYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLAQKLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     ANISQLAPELSALDNVQDSVIRSLLHAKLLEAKLQGIDVYIDIPETLARSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(2622..3968)
                     /locus_tag="TVR04_001868"
                     /pseudo
     CDS             complement(2622..3968)
                     /locus_tag="TVR04_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
BASE COUNT         1427 a          861 c          728 g         1115 t
ORIGIN      
        1 aggcagtaaa ataaccaatc catatcatga ctaataatag cttgtaatga tactttaata
       61 aaattaacga ttactttacc gaaaattcat ttagaatatg atgttttcct aggtatttat
      121 cgtgtcattg acaatctcca aaatattagt atcactcact tctgttatcc aaaagcgcta
      181 gcctctatca cctgctggta atgagctaac tgtttactct aacaaacagt tcaacgcttg
      241 cttggtcatg aatcaagtga gagagaaaaa aataaagccc ggcaaaccga gctttatctc
      301 cgctgacttg agcatcagca aatatgatat ccaaacaaag acaactgaaa caatcatttt
      361 aataacaagc agccatatca aaaatactat ttgtttatgg agagagagaa aacaatattt
      421 tgattgaatt ggggatggac cactccatta cctaatgatt tcgtaaatct ttattcatac
      481 tagacattat agcgaaaaat cactaaaaaa gatgacaatt tcctgaaatg ttcatttttc
      541 gtcctaaaat gtcattcaac ttaattttta gcgaaaagac ttccactttt caaaaagctg
      601 tttcattctc aaacgagaga ccatacaaga atcaccattt tcaaaataca ccaattgctt
      661 agccttatca attcgaacaa cattgtcaag attgaccaag taagaacggt ggcataaaaa
      721 cagcttagga gctaccgcat gaatctcaga taagttccca taaaattcta agcgctctgt
      781 ttgcgtccac aggcacacct tgtgaggcgt tgttgcagtt gcaaaataaa gaatgtcctt
      841 ataaggcagc tttaggcggg tctgcggggt ctcaaacaaa aacatctctt ctacttgacg
      901 actcgacatc atctcatagg tgtagcgaat acattcctca atgcgctctt taaattgctg
      961 actatcaacc gctttatcaa taaaatccaa ggcagacacc ttgtacctaa aggaaatagg
     1021 ggcgaactct gaatgcgtcg tgacaaaaac aagcacagca ttgggatcct tctggcgaat
     1081 atctgaggct agctctagcc cacttcttga tttgtcacca atttcaatat ctaaaaaata
     1141 cagctgatga tctcctctct cctgaatgct atcaaacagc ttttgaggat ttgaaaacac
     1201 ctctaattgg ttatgaggaa tcctaccctc ttctaatatg gacgccacaa tggcctcaat
     1261 acgactttgt tgaatcagat tgtcttccaa aataaaaatg tttagcatgg cttatctcat
     1321 ttctaacaat tgtctcaaac ggtagtgatc acttttggtt gaaaaggtga tgtggggata
     1381 acgctctaac acagccgaga actgtagcag gcgcttatga gcatggcttc ctagctccaa
     1441 tcggctagca tcaaattgct tagcaatatc aacccgcttg agccttgtac tattttcaat
     1501 gataaaaaat cgcttgccat cttgattaaa ataggcaatg gataaaaaag gacgagagct
     1561 gcctttagct gacaaaatag cattatcaat aactaccttg aaaagaacaa tgacatctaa
     1621 cagcctgaca gaagacctag caagcgtttc aggaatgtcg atgtaaacat caatgccctg
     1681 cagctttgct tctaatagct tggcatgcaa gagactgcga atcaccgaat cctgaacatt
     1741 atcaagggct gataattcag gggctagctg actgatattg gctgctgatt cttggataac
     1801 tgtttgataa accttggaga tagcagctat atctccacta tcaatactgt cctttagact
     1861 aattagaata ttttctgaat catgcttaat ggccctaatc tcacgacaaa gccgctcaat
     1921 atactgattg tgcttttcaa gataggcaac acgctctttt tgtgccagcg ctaatttttg
     1981 agctagttgg tccttagcaa aacggtccag cttgacaatg acccagatga gcagcatgag
     2041 gtaaagaaaa atcatgacag agcggtaacg aaagtaaaac ttgagaaaat caccttggat
     2101 attgatcatg caatgaacca taacatagta gaacagcaag gctgcattca tccaaaagac
     2161 ccacttcttt agcttgtcct cgctgataaa tttgataagg gtcaaatcaa cgctaaaaat
     2221 atagctaaac aggtaaaagg ccggcaaaac taaggcatga cagatcatca acagacttat
     2281 gtcattattg atttgatgaa tgctgtagcc taaaaccgct ggcaaaagga aagaaccaat
     2341 aatacgaaag agcagctcaa caatcataat cgcaaacaag ccattaaaca gatgctcaga
     2401 agccttttta tgaggtgcaa agccaacact gacagcaaca aacaccagct gatcaactaa
     2461 cagcacatga tccagcagca gattagcaac aacaaagcag gcaccaacca aaagcaatga
     2521 tctaacagct agcttaatgc ctgaaaatgt cgaaaagatg acccagctat tcacaaagat
     2581 cagagcataa aagaatgaca tacctagcat aaaataaaac tctactcttt ctctattttt
     2641 ggcatgatta gggtctgact aaactgataa tcatgactct tggtgcgcaa ggatagctga
     2701 gggtatttct gcaaaatccg cttggcatta gacaagccta tccctcgacc gctccccttt
     2761 gaggaatagc cctcttcaaa aatcttatta atcatgaccc tttcgtcctt ggtcgtattg
     2821 gtgacggtga aaatctgctg atcatcagat aaaaagtagg ctatcgccac tgctggctgg
     2881 gctgtctcta gagcagcttc aatagcattg tcacaaaaaa tagatacaag cagcaataaa
     2941 tcaagctctg agatatagct atcccgaatc cgatctggaa cttctaggct taaggcgatt
     3001 cctgccttct cagccttaat gatttttgat gatagcaagc tttttatcga ggatacactg
     3061 attttactga gctttgaaat attgtaatgc ttatcgtccc aataatccgt cgcctcatct
     3121 accgtttagg catagacagt ctgtacatct gacacagagc cagagtcaat agcctgcccc
     3181 agcctttcta gcctcttgag gtaatcgagc tgaaatacct taacaccctt ataaagcttt
     3241 tctagatgct ttccataggt ttccagatta gcaatataag cctgctgttc cttttttaat
     3301 tcctgtttta agaattcctt tgattgatga ttaaaataag acagtaaata aatcaacaat
     3361 agggtaaaga tgagaaacag caccttataa gacgttgaca tcattatcgg ggatttaagg
     3421 tcaagaaagg gatcagtaaa tcctaaaatc ataaagagat caatatagta ggccaaacta
     3481 aagagcaaaa ataggctata aaagctgctg gccttgtcaa acctatcggc cttaacaatc
     3541 tgcttgtaat cctttcccac aaaataatta atcaaggcaa agcttgggaa aatcatcaca
     3601 taagcaataa agtctaggac aaggtgtcta acatagccgc cattaactga aaaaatataa
     3661 ggaagcacaa tcgctaaaat aaagcgcgat aataaatcaa caaacactcc aggaacaaag
     3721 gctaagaata aggcctttaa gctaaagcag ggccgctttt ctaaggccaa tacagctagt
     3781 agcaaaaaag gatcaatcat caagggcggc aataaagcaa actgattcaa aaagagagct
     3841 gctgtcagga caaaaatctg cttccaaagt gccagcttaa tgtctgataa aaaggaaaaa
     3901 atactaattt ctgtcacata ataaatcatc agtgatagta ataaaaagag ataataaata
     3961 tcagtcattc tgcctcctta ccaactttat tattttaaca cactttgtgt caatccctat
     4021 tatatgaatt ttttatataa ttcagcaagc gcaaaaacag tccatagctg gtttgtgaca
     4081 gcgtttgcaa atcagatgtc aatcattaaa gcaaattaaa atatctgacc a
//
LOCUS       DARYSY010000093         3973 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYSY010000093 DARYSY010000000
VERSION     DARYSY010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3973
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..303
                     /locus_tag="TVR04_001869"
     CDS             <1..303
                     /locus_tag="TVR04_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1270534.1"
                     /translation="QNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRSDASS
                     AIDLSHNVSAQVVGIITSMSQHIQSVSASFQAMDLQLGKELGRLESKRRFSLNDPK"
     gene            308..640
                     /locus_tag="TVR04_001870"
     CDS             308..640
                     /locus_tag="TVR04_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1270535.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYAELSDLAAQLLAETAA
                     TLRSSLDSHFFEGALAENHYLERKTQASLEQSHEELLGEQRRLYQEEEALTRQLRLVK
                     GKERANEH"
     gene            642..2240
                     /locus_tag="TVR04_001871"
     CDS             642..2240
                     /locus_tag="TVR04_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270536.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYRSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQEVPNYSYIANLKSGESNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNTGIRQTKTSWNGTSRTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLKQAAEKLSRETGIKYEDAYRFVMDGVLSDENRNKIKSVRKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKDKVFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKGLSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGNVGKAASKVLKFAGKGLKVAGWVGAAINVKDSAETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRLAGAAVGQIIIPIPGVGAAIGSVVGSIAGGWLGSI
                     VGDIVNTQLDKTVKPKQSGRSLVW"
     gene            2234..2920
                     /locus_tag="TVR04_001872"
     CDS             2234..2920
                     /locus_tag="TVR04_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270537.1"
                     /translation="MVMLMRTLLFPIDNGMDSNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIVVRRLGVFNSDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEEEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     FFLTFLAIPIAYYAYFHPRSFGDYLAALSVTSLLISLIPQFLWNLIIKHIIYIKLIRK
                     TKERILESER"
     gene            2942..3625
                     /locus_tag="TVR04_001873"
     CDS             2942..3625
                     /locus_tag="TVR04_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270538.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGNGLAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPNKEQQHLYFKTMYDITIRKNDIMPQNSIPFLGTYIAF
                     LIAFSVIPIFYFQYLQQNSFWSYLETLVGSSILISLIPNFLWNVLLKQLIYIKLIRKT
                     KEKILKNET"
     gene            3653..>3973
                     /locus_tag="TVR04_001874"
     CDS             3653..>3973
                     /locus_tag="TVR04_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270539.1"
                     /translation="MLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDNKI
                     RTQQKVAFVLNLIAGSLSPLAIFLFVVIVRRLGVFSGDTNSMIFKWAPLIVGFILFIS
                     FELLM"
BASE COUNT         1236 a          685 c          910 g         1142 t
ORIGIN      
        1 caaaataata gcagcacagc tagtgagcga gcgacagctt tggcaagagg agtccaggcc
       61 ctctctagtg ctggtgcggt gagcaaagat atgaagacaa ccgttactgg aaatcgtagt
      121 gatgccagtt ctgccattga tttatcgcac aacgtttcag cacaggtagt tgggatcatt
      181 acttctatgt cgcagcatat tcagagcgtt tctgcctctt ttcaagcgat ggatcttcag
      241 cttggaaaag agttagggcg tttagaaagc aagcggaggt ttagtctcaa tgacccaaaa
      301 tgagctaatg taccagaagg aaagattaga taaacgcttg gaaactatag cccaagagct
      361 caagcgtaat gaacagcgct ttgaagacta tgcggagcta tctgatctag cggcacagct
      421 attagcagag actgctgcca ctcttcgctc gtcgctagat agtcatttct ttgaaggagc
      481 tttggcggaa aaccattatt tggaacgaaa aacacaagcg tccttggaac aaagtcatga
      541 ggagctctta ggagagcagc gtcgtttgta tcaagaagag gaagccctta cccgacaatt
      601 aaggttagtc aaaggaaagg agagagctaa tgagcattga catgtatctg gggtcatcgg
      661 accagcaggc tagtagcgtt ggtaaggtct tgcagcagcg gataaccgct tataggtctt
      721 tgcaaagagc cttggagcag ttggtgtcct ctagtcctga tttatcaggg catacctatg
      781 cttctgctaa aaggtacagc gagcaggtat tgatcccttt gatgaggggc tgtatcctgc
      841 tagacgaagc catcaaggaa gcctgtgcag catttcccaa tgactaccgt cgtcaggttg
      901 atagtgtgga tttgaaggag agtgagctgg tggatcagat cagccgctca gaccgcatca
      961 taggtcgtta tgttgagttg attgacctgg agtatcggca ggaggtgccg aattactctt
     1021 atatcgctaa tctcaaaagt ggggagagta accagcgtca agtcaagaga aaattagaag
     1081 agaagctcct taagctgcga gagtttgaca gcaattctcg tcaccttttt tcgtctatcg
     1141 cagccttagc cgaggcagtc aatacaggta tcagacaaac caagacctct tggaatggga
     1201 caagtcggac gttcaccctt cctagggctc ttgatctaga gtggaccaag gtagtagaaa
     1261 agaggtggac gcaaagggag gaaaaagcct cgaagcttaa gctaaagcag gcagcagaaa
     1321 aactctcaag agaaactggg attaagtacg aagatgccta tcgttttgtg atggacggtg
     1381 ttctgtcaga tgaaaatagg aacaaaatca agagtgtaag gaagctagtc aagtatacaa
     1441 agggtgggct gtatatcgtt tcctcaggaa gatattattg gaaacattca ggtaaacatt
     1501 attggaaaaa tacaccaaac aaaacatgga atatttggaa agcgtctaaa aacgatccca
     1561 attttgacaa gggagggatc aaagataaag tcttctctaa aaaaggagcc cgttacacag
     1621 acttacctgg tatcaagcaa ttgaagaaga gtgaaacagt acaatccctc atttcaaaaa
     1681 tttcaaaaga taatcaaggg aagctcacca aagttggtaa agggttaaag aaagttgata
     1741 aagggctaag caacatatcg tcaaaactca agtcatatga gcatggacgc ctaaatagag
     1801 acttgaaaat gatgaaggag aataacctgg gtaaaagtct cggtaagttt gggaacgttg
     1861 gaaaagctgc aagcaaggtg ctcaagtttg caggaaaagg tctcaaagtt gcaggttggg
     1921 taggcgctgc tataaatgtt aaggactcgg ctgaaactta caagaaaaaa ggctatagca
     1981 atgaacaaac tgctgcttta acagcccgta aggtagctgt cgatactgca acaactgttg
     2041 tcggaagcaa tatcggtcgt ttggctgggg cagctgttgg tcaaataatt attccgattc
     2101 cgggagtagg cgctgctatt ggttcagtcg tgggtagtat tgctggaggg tggcttggca
     2161 gcatagttgg tgatatagtg aatactcaat tagataaaac tgtaaaacct aaacaatcag
     2221 gaaggagttt agtatggtaa tgttaatgag aaccttgtta tttcccatag ataatggtat
     2281 ggatagtaac ttaattggag acggcttatc agctgagtat gatttgtgga ctggaaaggt
     2341 cacgtggcgt cagcccagtg atgataagat tagaacccaa caaaaggtag catttgtact
     2401 taatctcata gctggtagct tatctccatt ggctatattt ttatttgtta ttgttgttag
     2461 acgtctgggc gttttcaaca gtgacactaa ttcaatgatt ttcaagtggg caccgctaat
     2521 agttggattt atccttttta tatcgtttga attattgatg ctggcgctta gaagtagata
     2581 tacgatatta gaggaagagc ccgatttaga tcgtcaacta tactattatc gtacaatgta
     2641 tgataatact atacatgaca attcaggtgt ttttaataat ttatcagtac cttatgtagg
     2701 tctatacatc actttctttc taactttttt agcaattcct attgcctatt atgcttactt
     2761 ccatccgcgt tcgtttggag attatcttgc tgcattatct gtaacaagtt tgttaatctc
     2821 gctaattcca caatttctat ggaatcttat tattaaacac attatttaca tcaaacttat
     2881 tcgcaaaacg aaagaaagaa ttttagagag tgaaagataa acaatcagga aggagtttag
     2941 catggtaatg ttaatgagaa cactgctatt tcccgtagat aatggaatgg gaacgggctt
     3001 gactggaaac ggactagcag ctgagtatga cctatggact ggaaaggtca cgtggcgaca
     3061 acttggtgat ggaaaaataa aaaggcaaca aaaggtagca gctataatta atctcattgc
     3121 agctgcaata tctccacttg tcatcatgtc tatcattttt acggcaaaaa gtctgaagct
     3181 ttttgatgta gatactagta caacaattta tcgatatgct cctctgatgg taggcttggt
     3241 ctttttcttc tcgtttgaat tattaatgct ggctattaga cgtctgtatc cgttagccaa
     3301 agaggagcct aacaaagagc aacaacattt atattttaaa acgatgtacg atataactat
     3361 tcgcaagaat gatattatgc ctcaaaatag tatcccattt ttaggaactt atatagcttt
     3421 tttgatagcc ttttcggtta ttccaatttt ttactttcaa tatttacagc aaaattcttt
     3481 ttggtcctat ctggaaactt tagtaggaag tagcattctt atttccttaa tccccaattt
     3541 tttatggaat gtcttattga aacaattgat ttacatcaag cttattcgca aaacgaaaga
     3601 aaaaatctta aagaatgaaa cctaaacaat caggaaggag tttagcgtgg taatgttaat
     3661 gagaacactg ttatttccca tagataatgg tatggataat aacttaattg gagatggctt
     3721 atcagctgag tatgatttgt ggactggaaa agttacgtgg cgtcagccca gtgataataa
     3781 gattagaacc caacaaaagg tagcatttgt acttaatctc atagctggta gtttatctcc
     3841 attagctata tttttatttg ttgttattgt tagacgctta ggcgttttta gtggcgatac
     3901 taattcaatg attttcaagt gggcaccgct aatagttgga tttatccttt ttatatcgtt
     3961 tgaattattg atg
//
LOCUS       DARYSY010000094         3906 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYSY010000094 DARYSY010000000
VERSION     DARYSY010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3906
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..1205)
                     /locus_tag="TVR04_001875"
     CDS             complement(<1..1205)
                     /locus_tag="TVR04_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1270540.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLGDVIDKV
                     YTRDVFGRD"
     gene            complement(1459..2712)
                     /locus_tag="TVR04_001876"
     CDS             complement(1459..2712)
                     /locus_tag="TVR04_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1270541.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRETGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVYAATGHLNVRNREVNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSIYRREVVVPNIDKYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3109..3729)
                     /locus_tag="TVR04_001877"
     CDS             complement(3109..3729)
                     /locus_tag="TVR04_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270542.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3770..3865)
                     /gene="ffs"
                     /locus_tag="TVR04_001878"
     ncRNA           complement(3770..3865)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TVR04_001878"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
BASE COUNT         1196 a          868 c          715 g         1127 t
ORIGIN      
        1 tagtctcttc caaagacatc tctcgtataa accttatcaa tgacatctcc taggtcgtcc
       61 tcaaagcgat ttgacacaat gattgtagac tcgtttttga actgctctaa gtccttgaca
      121 accctgtagc caatatcctc gccaagcatg ggttcgtaaa tgacaatatt aaccccatag
      181 tcgttgatga tatcaataat atctttaatg gcgctttctc ggaaattatc agagttgctt
      241 ttcataatca agcggtaaaa gccaatcgtt aatggtacac cagcctgctt ttgactagag
      301 gctctgtcta atatttgttc agctaaatag gattttcgta tcttgttgga ctcaacaatc
      361 gctgacatca aggactgggg aatgcctcta taatttgcca acagctgttt gctgtccttt
      421 ggcaggcaat agccgccata tccaaaggaa gggttattgt aatggttacc aatgcgctga
      481 tcatgacaga ctccttcaat cacgcgctga gcatctagac ccttgctttc ggaataggtg
      541 tctaattcat taaagtaaga cacccgcata gccaaaaagg tattcgcaaa tagcttgacc
      601 gcctcagcct cctgtgagcc cataaataag accggagtat ccttgctttt ggctccttcc
      661 tttaaaagac cagcaaaggc tttagcagcc tgaataaccc ttggtgagtc gtccttttca
      721 taagaaacaa tgattcgact tgggtaaagg ttatcgtata aggcttttga ttctcttaaa
      781 aattctgggc taaaaataat acgatctgtc tggtattttt ccctaacatg cttgataaag
      841 cctagtggta tggttgattt gataataatg gttgctgacg catttaggtc taggacctgc
      901 tcaatgacct cttcaacatg ccttgtgtca aagtagttgc gttcgctgtc ataatttgtc
      961 ggagtagcaa tgataataag gtctgcattg ctataagcgc ttgcgccatc aagcgtcgct
     1021 gtgagattta gcggtgcatt ttttaaatac tcctcaatat cagcatcctt gattggagat
     1081 atgccttgat tgatcaatct caccttttca tcaataatat caacaacagt gacgtcatta
     1141 tgttgtgcca gtaaaatact caaggatagg ccgacatatc ctgagcctgc tacagaaatt
     1201 ttcacttcat tttttccttt gataccttag tacagttagc tactgccgga gctcaggtgc
     1261 cacacctgaa ggaccatgat gacctagccc tcataccaaa gctgacgctc agcctctggt
     1321 tcgtcttcac agggctacaa gctaaaagct cttaactcaa gtacaagtgg actagcttta
     1381 atttgatgag ctgcttaact caagatgctt tgttcactcc tagcttagct cccttgtcag
     1441 aacctaggtc tagttggttt ataataattt tttacgtgtt ccccagtcag catttctaat
     1501 agtaaaaaga gaatacaatt tcaagggctg taggacaaac aaatgcagca ccccataaaa
     1561 cggagataac aagaaggaca gcgggtgctt aagcatgtaa tgaatgttcc gacaaagagc
     1621 aacaatgaag ataatcacca gaaaggctaa aaccctgagc caatcaaatt ctctgacatt
     1681 gcctacaaag aaatccacca cagaataaac aagcatcata aacatagaca cctcaagtat
     1741 ggtccatagg gctacaaaag gattgttcat gattttctta acagaaataa tggactctct
     1801 aaagaaggac ttgttccagc ggttttgctg cttcaagtaa gtagacatct tgtcaggaac
     1861 atctgtaata catttagcag tagattgata aacggtcttt cctaaatcag ttgcatagtt
     1921 ggtcaagcac ctatcatcac cgatgcttac aggaatgcct aagaaggttt gattgatgta
     1981 tttatctatg ttaggtacta caacctcgcg tctgtaaatg ctaagaggtc ctgagcaaac
     2041 aaggatatta cctgtaacgg attgggcagc tcgctccacg ccaaaagcat tatcatagcg
     2101 aatatccgtt aaacgcgtta gaagattcac ttctctattt cgaacattca aatgacctgt
     2161 agcagcatat actgttgggt cattaaaggt ttttaacagc tcctccaaag catcagggta
     2221 gatataagta tctgagtcaa cggtcaaaaa gacatcagcg tctgatcttt caaaggccca
     2281 ggcctgtgca tgacgctttc cttgattttt ctctgaccga tgaacaatga cattgcttga
     2341 taggtcacca gtttcacgca catagtcttc aatgcgctta atacctgtct catcagcact
     2401 tccatcgtca acaacataaa tttctgctag gggataggtt tgctgctgaa cactttttaa
     2461 ggtctctagc aatgactcag catcttcgtt ataagaggga ataatggctg caaccttata
     2521 ttgcccagcc cttcccttaa atggcttgta aaaaaaggat aaggacattt tgactaatag
     2581 gtaagctatc agcaaaaagc cataaattga caagcttcct ttagcaccaa agagataaac
     2641 attgacgtaa atcaacagta cccaaaaaat actaaaggcc acaacagtta tgaggttttt
     2701 taatgttctc attgtgattg gtttgttcct ttcttgcgct ttgtattttg cctttaaacg
     2761 ctaaccataa tatactatct gtcacagcaa gcaaacaagg tcattaattt accattctat
     2821 taaagataga ttaatcttag tgtcaataca gctttttcta agatttgcct atgctcacca
     2881 agtcatcaat cccctacaaa aaacaaatga tagcctgagt ttacctgtgg ctatcgctag
     2941 catgtgcctg ataacaagca gctaaatggc ccgtccaaaa ctaaagcgct ttggacagcc
     3001 gcttttcgct ctcttttttg acatcaaaaa agcggccctt atcaggccac ttcatattgg
     3061 taataaagca attctataag gagctcctta acggataagg gtaagaggtt actttagaga
     3121 cttgatgatc tcaatgcgag tgataacccc ctcatgcata tgatctactc ttaaggcaac
     3181 atcagaaaaa gcaatagatg ccccaatcgt tgcagtcttt ccttcctctt ccaaatggcg
     3241 cagcattaaa tcacgcatta gctcgttttt gttaataacc ggcagctcga cacgcgctag
     3301 cacattagct attttgacct tttgactgcc ccgaacgata atgcttgaag tatcatcaaa
     3361 gcttgtaaaa aggtattttc gcgtcgcaaa taaaatagca agagctatga cactcaataa
     3421 agaatcctta gcagagccat gagcgacaac aatttgccgg gcaatcgcaa acaaaagcac
     3481 ctcaataatg gttcctgagg tatgcttact cagcatttta atcagctcga caccaatagc
     3541 aatactcatg gcctgattta aaaagctctg taaataggta tcaatgccac tctttatggt
     3601 aaaaatacct gtcaagctca aggccaagcg ccctgtcagc actagtaacg aaatcaccaa
     3661 gatgatggaa ataataatct caacataatg agatagctca tacaatctaa tctgcaaata
     3721 ttttctcata gcaactcctt atcattatta tataaaaaat gtcactcttt gaaaataaaa
     3781 aaagagcaca cgcctgacat cgcttagggc tgctggattc ctcccctgac ccacttcacg
     3841 cacaagtgtt gctccacctc tattgtagca tatgttgtac cctaaaacaa gtcttatttc
     3901 aaaaac
//
LOCUS       DARYSY010000095         3845 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYSY010000095 DARYSY010000000
VERSION     DARYSY010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3845
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            57..572
                     /locus_tag="TVR04_001879"
     CDS             57..572
                     /locus_tag="TVR04_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270543.1"
                     /translation="MYADSNLKFEEISSAAKLILSLYRQVTWAIDSRANFMMFESKEN
                     YGSTSESAYLYLSTFAPEKVEEKFNNRVSNVMDSKLMLLIIYDACVRLKVYPEYGEIY
                     HKIIYNYYIAEKKITDEACMRSVSLERTVYYQRKKEAIALVGVIIWGYTLPTAISQLK
                     DGRSIEEIMNI"
     gene            841..1251
                     /locus_tag="TVR04_001880"
     CDS             841..1251
                     /locus_tag="TVR04_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1270544.1"
                     /translation="MDKEYYLFVEGKKVIVSKEVYLAYHSELNKEKYQMRRDRLNNCF
                     FFCSYDHDGNFEENLEDLEFDVEKIIETKEMIEEVRRAISKLNPVERDLIESLFYKEE
                     TIREVAAKLNISNPAVIKRRNKVLEKLKEMLEDF"
     gene            1728..1949
                     /locus_tag="TVR04_001881"
     CDS             1728..1949
                     /locus_tag="TVR04_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270545.1"
                     /translation="MLLIQGTCQCQKTLILYCEVKPMNTKEKKKYKPKEQISKEDYSK
                     KITYTQSDKESLDLLDIVELYLCRACIRL"
     gene            2050..3720
                     /locus_tag="TVR04_001882"
     CDS             2050..3720
                     /locus_tag="TVR04_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1270546.1"
                     /translation="MEKFACMYLRLSREDGDSTESNSISNQRQIIKSYARDNDFKVVA
                     EYVDDGFSGSNFDRPKFKKMIQDLEEKKFKTIIVKDLSRFGRDYIESGKYLQKIFPEK
                     GIRFISVNDNYDSENADVSDTHLILPIRNFINDSYCRDISMKVKSSKEIKRKNGEFIG
                     AFAPFGYKKDSKNKHKLVVDTEVSHIIERIFNMKIDGYSSKAIADFLNSIGCVTPSKH
                     KENSGDNHTTGFIVKDSKWDAKMVNRIITNKVYIGVLEQGKTRKLNYKSKREVEVNEE
                     DWIVINDSHKPIISKSIYALANKMMLRDVKQSADIPHILSGMLYCKDCGSSMVRRKVK
                     SKNGYNIFYICSHYNNKGDCTRHSIKEDYLLDMTLFALKDYLKKYNELLSQVNKLDVS
                     KVTFNIDFESLNSEKRKYERLRQSLYMDLEDELITSEEFERFRKNYLIKIREIEKQIA
                     TKKNILANLQEKMKKKDSLVSEIVPTDLSSLNRLTIVSFIDRIEIGENNEINFVFNNL
                     ETVNLLKTLIKEESENKSEVKKNLISINKVFGNALENKTPMQLAGGVL"
BASE COUNT         1504 a          463 c          711 g         1167 t
ORIGIN      
        1 attgtattgg ggtgattaga ttgagaataa gtaaaacttt aaagaatata atgcacatgt
       61 atgcagatag caacttgaaa tttgaagaaa ttagttcagc tgcaaaactt attttaagtt
      121 tatatagaca agttacctgg gcaatagata gcagggcaaa ttttatgatg tttgagagta
      181 aagaaaacta tggatcaact tcagaatctg cttacttgta tctttctaca tttgctccag
      241 aaaaagttga agaaaagttt aataatagag tttccaatgt aatggatagt aagcttatgc
      301 ttttaataat ttatgatgcc tgtgttaggc taaaagttta tccagagtat ggagaaatct
      361 atcataagat tatttataac tattacattg ctgaaaaaaa gattactgat gaagcttgta
      421 tgagaagtgt atctttagag agaactgttt attatcaaag aaaaaaagaa gcaattgcat
      481 tggttggtgt aataatttgg ggatatactt taccaactgc tattagccaa cttaaagacg
      541 gtcgcagcat tgaagaaata atgaacatct aagaaattaa tttatgacga acttattgcg
      601 tactatttcc gaatgaaaaa agtaccatat acgaatttta tgtgtactta agtgcatata
      661 taatatccat gatgggttat ttgcacctaa attttatatt ggcatttatt gactgaaaga
      721 atttattttc tttcggtctt tttttatgcc caggagaata tatgcaaaga attagaagcc
      781 ctccttgtgt gaatttcatt tttaaacaaa agaaattcat gtcaacaagg aggaaaatta
      841 atggacaaag aatattattt atttgtagaa ggaaagaaag taattgttag caaagaagta
      901 tatcttgctt atcatagtga attgaataaa gagaaatatc aaatgagaag agacaggtta
      961 aataactgtt tctttttttg ttcctatgat catgatggaa acttcgaaga aaatttagaa
     1021 gatctggaat ttgatgttga aaaaattatc gaaacaaagg aaatgattga agaagtaaga
     1081 agagctattt ctaaactcaa ccctgttgaa agggatttga tagaaagtct tttttataaa
     1141 gaagaaacaa ttagagaagt agccgctaaa ctgaatattt ctaatccagc cgttattaaa
     1201 aggcgtaata aagtcttaga aaaactaaag gaaatgttag aagactttta gatgacagtt
     1261 accaagaggg tctaattttc actgttactt atgcagtggg aattggacct tttcatttaa
     1321 ccaaatttat ttttgaaaat tggttagcaa gaaaggcttc ttttcactgt taagtataag
     1381 agggtaattt taaacaattt tgtttcatca agataagtat tttctgatgg tcaaatttta
     1441 aaaagattaa taactctcga taaattttga accttaacaa ttgaatagac caagacaaga
     1501 cgttaatcat ttttggagcg tgataaccta tccgccaaga tctttctgct gaataattcg
     1561 gcaaaacaag tactgctaag ctaaaagcaa gggaagaaga aagagagcga taagtaagag
     1621 tttgaatata gggagggata ccctattcgc tatgaagaaa atgaggataa tgatacttct
     1681 aaggttgaag ccggctcatc ctgaacagag gcggaggtga gattcctatg ttgctaatcc
     1741 aaggcacttg tcaatgtcaa aaaactttaa ttttatattg tgaggtaaaa cctatgaata
     1801 caaaagaaaa gaagaaatat aaacctaaag agcaaatatc aaaagaagat tattctaaaa
     1861 aaattactta cactcaaagt gataaagagt ccctcgactt actagatatt gttgagcttt
     1921 atttatgtag agcttgtata agactataag ctggggtgct gacttaaaaa cttgggtgcg
     1981 gtaaaatata agtggtagaa gaactcctta atgactattt gcccaaatac aaattaagga
     2041 ggttttgtga tggaaaaatt tgcttgcatg tatcttcgtt tatcgagaga ggatggagat
     2101 agcacagaaa gtaattctat ttcaaatcaa agacagatta tcaaatcata tgcaagggac
     2161 aatgatttta aagttgttgc tgaatatgta gacgatggct tctcaggatc taattttgac
     2221 agaccaaaat ttaagaagat gattcaagat cttgaagaga agaagttcaa aacaattatt
     2281 gtgaaggact tatcccgttt tgggagagat tatatcgaat caggtaaata tctacaaaag
     2341 atatttccag aaaaaggtat aaggtttata tccgtaaacg ataactatga cagtgaaaat
     2401 gcagatgtaa gcgatacaca cttaattctt ccaataagaa actttattaa tgattcttat
     2461 tgtagagata tttctatgaa agttaaatct tcaaaagaga tcaaaagaaa gaatggtgaa
     2521 tttattggtg catttgctcc ttttggttat aagaaggata gcaaaaacaa acataagtta
     2581 gtcgttgata cagaagtttc acatataatt gaaagaatct tcaatatgaa gatagacggt
     2641 tattcgtcta aggctattgc agatttttta aatagcatag gttgtgtaac accatctaag
     2701 cataaagaaa attctggtga taatcatact actggtttta ttgttaaaga ctctaaatgg
     2761 gacgcaaaaa tggtcaatag gattattaca aacaaggtct atataggagt gcttgaacaa
     2821 gggaaaacta gaaaactaaa ttacaagtct aagagagaag tagaagtaaa tgaagaagat
     2881 tggattgtaa taaacgactc tcataagcct attatttcaa aaagcattta tgctttggct
     2941 aataagatga tgctccgaga tgtaaaacaa tcagcagata taccacatat tttatcagga
     3001 atgctttatt gcaaagattg tggatcttca atggttagaa gaaaggttaa gtccaagaat
     3061 ggatataata ttttttatat ttgttctcac tataataaca aaggagattg cacaagacat
     3121 agtataaaag aagactatct acttgatatg actctttttg cacttaaaga ttatttaaaa
     3181 aaatacaatg aattactaag tcaagttaat aagttagatg tatcaaaagt tacatttaat
     3241 attgactttg aaagcttaaa ctcagaaaag agaaagtatg aaagacttag acaatcttta
     3301 tatatggact tagaagacga acttataact tctgaagagt ttgaaaggtt cagaaaaaat
     3361 tatcttatta aaatcaggga aatagagaaa caaattgcta caaagaaaaa tatacttgcc
     3421 aacctgcaag aaaagatgaa aaaaaaggac agtttggttt ccgaaattgt tcccactgat
     3481 ttaagcagtc taaatagact aacaattgta tcttttatag atagaattga aatcggagaa
     3541 aataatgaga ttaattttgt ctttaataat ttggaaacag ttaacttact gaagactctt
     3601 ataaaagaag aaagtgagaa caagtccgaa gtaaaaaaga atttaatttc aataaataag
     3661 gtatttggaa atgctcttga aaataagact ccaatgcaat tagctggagg tgttttataa
     3721 tggcaagaac ttccaaaaga tatattgaaa agaaaggcga aaagacagaa agaaaagtct
     3781 ttaaggccgg aatttataca agactatcta acgaaagaac agaagagtgg agagaaaaat
     3841 catac
//
LOCUS       DARYSY010000096         3797 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYSY010000096 DARYSY010000000
VERSION     DARYSY010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3797
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(1..932)
                     /locus_tag="TVR04_001883"
                     /pseudo
     CDS             complement(1..932)
                     /locus_tag="TVR04_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(1985..2419)
                     /locus_tag="TVR04_001884"
     CDS             complement(1985..2419)
                     /locus_tag="TVR04_001884"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1270547.1"
                     /translation="MIYIDEMIGQEVEMDEFSQMEATEEIAMKIEEKTLDMMEKDLEF
                     MERFPNPTYAVLRLSYLVGSEDMENWKKLQEMYEEKTLLNHLKEIQNQAVDFIKREKV
                     KMMKAQGLTEKMMRENPEEYQGQMNNLMATVKKMAIKEYVEA"
     gene            complement(3190..>3797)
                     /locus_tag="TVR04_001885"
     CDS             complement(3190..>3797)
                     /locus_tag="TVR04_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1270548.1"
                     /translation="KGVLDRNMRDSFFIYLKELESLGYESKYEILNAMDFGIPQKRER
                     IFVVSCLGANNFSFNKLERKETRPLSEFLEKNVSEFYTMTQPYMLKFLNKGIDNSFRG
                     RLKVIKDFSYTISTKQMRVPNSGIIDIGNGQYRYLTERECLRLMGFDDSDIDKLEKVH
                     PRRKNCTSSKLYKQAGNSIVVDVLMAIIKEIHRMEVGNASK"
BASE COUNT         1049 a          813 c          440 g         1495 t
ORIGIN      
        1 ccaaatcttc cagatacctc tttcatatcc cctaatacca tctgaggatt atctacaaag
       61 tatttattgt aggtcaaacc ctttttatca gttgctaggt gtatccaatc gtcatctctt
      121 tctataactg aatctctctt ttttaagaaa ataatatctg aagtaacttc tgtaccagca
      181 agtcctttaa atgttgtatt aggaagcctc atagctccta aaaactcaca tcttgcatta
      241 atatattttc taacagattc atctttttta tccatagttc cagatgatgt tatgaaggca
      301 ataattcctc cattcctaac cttatctatt gactttgcaa aaaaataatc gtgaatcaga
      361 aagttatttc tgttatattc acgatcgtta actttaaaat ctccaaaagg aacatttcct
      421 ataactaaat cgaaaaagtt atttgagaag tttgtttctt caaagccttt aatttgaatg
      481 ttagcttcag gataaagttc tcttgctatt cttccgctta gactatcttt ttctactcca
      541 tatactttag agccttgtat ttcccttggc atattaccaa tgaaattgcc gacccctgca
      601 gacggttcaa ggatattccc agtcttaaat cccatatctg ttagagtctt atatattcca
      661 tccattacct ctctaggtgt ataaaatgat gttagagtag actctttagc attcaaatac
      721 tcatcatttg ttagattttc ttttaaaata tttcttgctt caagccattg tcctcccttt
      781 tcttcatcaa agacatcggc aagaccaccc catcctagat aatcagcaag ataggcttgt
      841 tcatactctc ttggactcct attttcattt tcaagtcttt tgagcatttt aatagctttg
      901 atatttttat ctagcttttc tgatggtgtt aggtattcag agtaaatatg atttttcaaa
      961 tcataatttc tagcaaagct tagcctttcc ttattaggtt catagcctaa attctttaaa
     1021 tcttctttac ccctcaataa gttttcggct gcttccctag gcacattgta tctatccatc
     1081 atttggtcaa tttcgggatt gtggttatca ataaagcttt cttgctctac ttgtctttca
     1141 atttgttttt catgctcagg taatttgtat atctcataat ttccactatc taaaaggtca
     1201 tcaatttttc tactctcttc aaatgtttca cccttatata agggaaattc ttccccatta
     1261 atttctactt tagtttctgt ttcaattaag ttaattccat caaagacatt ctcatcttct
     1321 aaaataaatt cctttccaac ttttactgct agtttttctg atgtttgact tagattttca
     1381 aagatttctt caaggtatga atcgtttcta tatggaatta cttccgaacc cctaatcata
     1441 cctcccatat attccatatt gtctctgata gtgacagttt taagtcctcc acttagttca
     1501 tcaaaatctg taattgtaaa gtccttatct ttatatctaa cttgatcacc tatcttaaat
     1561 ttaggttcta tcttttcctt aacttcttct tgtaatgatt tttcctcact tagtgcaact
     1621 tgttcttcta aatatgaaaa ttcacgctca tttacttctt ctccatcacc aaggtcaatc
     1681 ctataatgtt cgacaacttc gccgtctaca tagtggtcaa aatagaattt gaaatatccg
     1741 atataatcat cagtcatttc tccaaattca ttttctccat gagttagatt atggtcttta
     1801 acatctatat ccttttgtct taggacatta attaaatcct tagttactat ctgcccacta
     1861 taatcgggaa ctaattcgtg gttttcatta aattctacac tccagtagtc ttttctattt
     1921 tgaatgtttt tgccatcaaa aaaagaagct tcatcagctt ccttttcttg gcttatttcg
     1981 ttttctaagc ttccacgtat tccttgattg ccattttctt gactgttgcc atcaagttgt
     2041 tcatctgtcc ttggtattcc tctggattct ctctcatcat cttctctgtc aatccttgtg
     2101 ctttcatcat tttgactttc tctctcttga taaagtccac tgcctgattc tggatttcct
     2161 tcagatggtt caaaagtgtt ttctcctcgt acatttcctg aagtttcttc cagttctcca
     2221 tgtcctcgct ccctactagg taagacagtc ttagaactgc gtatgtcgga ttcggaaatc
     2281 tctccataaa ttccagatcc ttctccatca tatccaatgt tttctcttcg atcttcatcg
     2341 ctatttcttc tgtcgcttcc atctgtgaaa actcgtccat ctctacttct tgacctatca
     2401 tctcgtctat ataaatcatt ttgacctcct ctatcttcgt ttatattttc tatatctcta
     2461 ttatagtcgc caccggccct ttctgtcagc agcctagcac gatccatttc cttagatttt
     2521 tctattgtgc tatctataat atcttcacta acccttgata ttacaagacc tatctgctct
     2581 aaagaaattg tattaatcct agaaaaatta ttttttaaat tttccatatc catagggtag
     2641 actgtattaa acctattagc tactgcatag gatattgagt ccctcataaa cttttcaaag
     2701 ctaagtctat cctctatatc tattctcaaa tcagcaagag ccaagttaat gtattcatct
     2761 ccataaattc ggcttaaaga aaatatattt tcattaagtg aatcactagc ctcaaatgaa
     2821 gaattattta ttatttcttt taaagcctcg ttatggtttt cgtgatcaaa ctgccataag
     2881 ctaacctcat taatattcct atccattgat gtcgtctgac taatatcaaa gatgtatgaa
     2941 actctttgat ttatatcact tccaactaaa attggaatac ccttctctcc tctcataaca
     3001 actcgaccaa aatatttctt ccacatatca aaagtcgcac aagctctagc ttcaggttct
     3061 ttgttatata tacttaattg gctagaaaaa tcatatttct gattattgcc tataactttt
     3121 aagagcttta aatattcttt ttcatcttgt aaaacctcat actttattgc ttcttgtata
     3181 ttcttaaaat catttacttg catttcctac ctccattcta tgaatttctt ttataatagc
     3241 cattaaaaca tcaaccacaa tagaattgcc agcctgctta tatagtttgc ttgaggtgca
     3301 attttttctt cttggatgta ctttctctaa tttgtctata tcactgtcat caaaacccat
     3361 gagtcttaaa cattctcttt ctgttaaata cctatactga ccatttccaa tatctattat
     3421 tccagaatta ggtactctca tctgttttgt agaaatagta taagaaaaat ctttaatcac
     3481 tttgagtcgc cctctaaaac tattatctat gcctttattt aaaaatttca gcatataagg
     3541 ttgagtcatt gtataaaatt cacttacatt cttttctaaa aattcactta gtggtcttgt
     3601 ttctttcctc tccaatttat taaaagaaaa gttatttgct cctagacatg aaacaacaaa
     3661 tatcctttct cttttttgag gtatgccaaa gtccattgca tttaagattt catacttgct
     3721 ttcatatcct aggctctcta actcctttag ataaataaaa aaggagtccc tcatatttct
     3781 atcaaggact cccttta
//
LOCUS       DARYSY010000097         3781 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYSY010000097 DARYSY010000000
VERSION     DARYSY010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3781
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            573..1835
                     /locus_tag="TVR04_001886"
                     /pseudo
     CDS             573..1835
                     /locus_tag="TVR04_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2468..3214
                     /locus_tag="TVR04_001887"
     CDS             2468..3214
                     /locus_tag="TVR04_001887"
                     /inference="COORDINATES: protein
                     motif:HMM:NF020501.1,HMM:NF020502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1911 domain-containing protein"
                     /protein_id="HEL1270549.1"
                     /translation="MKTRDKLNTLENYQKVIMFHQCVIESDLEKIEDLLRDERNGIQK
                     SKIDNQQVIHNTKRWMARDLFKIFKATYSAGYPISEVKKAFLDYLDVKCQVLDGQVAY
                     LNDLDIISIAILLDIDTETIAPFIDNIEQVGYDDFLIDFLIRWYRPEWKQHDDISFKR
                     PYGHAQKIIQAPDKEQALGFLRNYIFSKWYAGSNDAPWYNNHKAKNPVFHVGYWSFES
                     GAMAKILELDDSSLKDQQYYPYDLVHWKNV"
     gene            3514..3781
                     /locus_tag="TVR04_001888"
                     /pseudo
     CDS             3514..3781
                     /locus_tag="TVR04_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1192 a          686 c          869 g         1034 t
ORIGIN      
        1 agatagactc tagttttgga gtgttttttt agatagcact cagctaagaa gataaggcaa
       61 aaggttatga cagaaaaaaa caagtccgat tcagtgatta gcaagaccat attaaaggac
      121 tagctccatt cttacctatc tgatgagact gactggttat ggttattagc ttaggaaagc
      181 caagagacgc ttctgtcaag agcacagctc acgataaatc aagtactttt taagagagtg
      241 agctggcttc acattttgca agataatgct atacctttct ctgtcgcaag ctgttcggcg
      301 ttcctgtccc tgtgcatttt ccccttgtag aatagcagta gctcccgata taggctttat
      361 tagcgccagg ctagtgctat tttcagcgct caacctttat gactgcttct cccaaaaagg
      421 cagataagtc agattttcaa tgacattcta atgcttttta gcccatacta ttatcataat
      481 attaattttt ttgttataat agactggtac attaagaaaa gatattgttg ttattaacaa
      541 gtgatttgat gtcatgaagg ctaggaggag aaatgaacta cagcattaaa tttgatgatg
      601 tcacctatct tcaaaacagt acacaaaaga cgatagaatc atggggagac tccatgtcta
      661 gcttacagac cgctatgtca gccttgattg gagacagtca ccttcagggc cagaccgcta
      721 gctcgatcaa gagctacctg agtgaggtgc atgggacact cttacaaacc ctgcaaagcc
      781 tgatgaatga ttactcagct agcctcttgc tgtataagga cggctattac cagatagaca
      841 gtaacagcca tgcccagcta ccaggtcagg tctttaagac tctgcagtca gagcttcggc
      901 tctcgcaggc tcacctcaag gatcagcttg agctactaca gaatgccaga gctaaggtat
      961 ctgacctagt acactactct ggtgtcagtc atgccaagac agtggtggat tatagcgagc
     1021 tgatcactga tatcaatcgc ttggacgagg ccatcattca atacgaaagc aatcatgcca
     1081 gtcaggactt atccgccttc aaggagcttt tggcttcgac caaggccttg atagcagaat
     1141 acagcagcaa gcccaagcgg gctgggagct atcaggttgg ggatatagga cagctcaaca
     1201 ccataaaacg ctttgcgaca gcctatcagg gagtggctcg tcaccttgag accaatgcca
     1261 agcgtctcca agcagcgcag gagcgggatc atgctcgttt tgaggcagta gctgcggagg
     1321 atagggccaa gcagggctgg atagatctag cgctcagcct tgtgacaata gcggttgggg
     1381 ttgcggctat cgtcatgaca gcaggagcag caactccctt ggttgttgga gcttgtgtgg
     1441 ttggcagtgg aacagttgct tatggcgcgt cgaatctgta tgaggctggc cacaacattt
     1501 atctaggtag cgttggtgat gggcttacag tggctaccaa tccccttcgg gataccttgt
     1561 ttatggggaa tgacaggctg taccaccaga ttggtggctt gttcacaaca gccagtgcag
     1621 tcatgatccc gatcggacag accaagagtg ttgccaaggg cttaacagag ttcacgatag
     1681 gggaggtcgg cggttttatc ggtggtcagg ccagctatca tggcactagg ctcttaggcg
     1741 gcagcgagca agacgcccaa agagctacat tagttgggaa tatcctagga ggctatgccg
     1801 cctcaagcgc cgccagaaga ttcagcttga atgagccaat agcagctagg gtgacgaaac
     1861 cgacctataa ccgccagcag cttttgaaga accttgaaag cagtagactg gcaaggcaaa
     1921 gctcgaggtt taagaattat gtagcaagag aaaagttagt ggggcttaaa acagctattg
     1981 ctagaaaagt aaaaggtttt aatccggaga tagctagtac caaacaaaag ggtaattttg
     2041 gtgagataat ggctgatgca aatttatcta aaccagtaca aggagatagg gttacatata
     2101 atcttcgtcg tgttggacgt gatgttccta gaagtcttga taccagacta gagaagggaa
     2161 ttgatggtat ctatataaac gaagcagatg gacctagcgt tgttattaac gaggcaaaat
     2221 atggttcttc tacgcttaat cccaaaacat cagatggtaa acagatgaat cgtgattgga
     2281 ttgaaaatag aatcatagag acaaattttg aaaatctaga agattattta aaggtacgta
     2341 atgctatgcg tcaaggtgac tatgattctg tgttaagtaa agttgatgca aagggtaatg
     2401 ttcatcacta tcgattagat gaagatgcta atatcataag tgattggccg taaaggaaag
     2461 gaaggctatg aaaacaagag ataaattaaa tacattggaa aattaccaaa aagtaataat
     2521 gtttcaccag tgcgttattg aaagtgactt agaaaaaatt gaagacttgt taagagatga
     2581 gagaaacgga attcaaaaaa gtaagattga taatcagcaa gttattcata atacgaaaag
     2641 atggatggct agagatttat ttaaaatttt taaagctacc tattcagctg gctatccaat
     2701 ttctgaagtg aaaaaggcat ttttagatta tttagatgtt aaatgtcaag tattagacgg
     2761 tcaagttgct tatttaaatg atctagacat tatttctata gcgatcttat tagatattga
     2821 tacagagacg attgcacctt ttatagataa tattgaacaa gtgggctatg atgatttttt
     2881 aatagatttt cttattcgtt ggtatcgtcc agaatggaaa cagcacgatg acattagttt
     2941 taaacgtcct tatggtcacg ctcaaaaaat tattcaagca ccggataaag aacaggcact
     3001 aggcttcttg cggaactata tatttagcaa atggtatgca ggttctaatg acgctccttg
     3061 gtataataat cacaaagcaa aaaatccagt ttttcatgta ggttactgga gttttgagag
     3121 cggtgcaatg gctaagattt tagagttaga tgatagcagc ttaaaagatc aacaatatta
     3181 tccgtatgat ttagtacatt ggaaaaatgt atgacattga caagttgaag aaactcatac
     3241 aaagtgcaga aaaagaacct tgagaacagc aggctagcaa gggagagctc aaggtttgat
     3301 gattaccttc gaagagagta ccagttaaaa ggaaggtatt ttgcagaaag aatcctcatg
     3361 ctagatggaa aatatgcttg tctgtccagt gaccttgata aagctaccgg aaccccaatt
     3421 cctgttcgat atagaaatta ccttaaggct gctggttcta ttagttggcc aaactataat
     3481 ggctttagtc ttgatttaaa gggaaggcct atcatgactc cagctttcct aaaaacaggt
     3541 gatttacttg ataggtatgg ggaatctgga ggaccgttca cgagtccaat cattaaccat
     3601 aaggttattt cctttaacaa gcgaggcata aggttatttc ctttaacaag cgaggcttac
     3661 cctatccaga gggctatcaa aattatcatc agtacaggat tcttcaagat attacaatag
     3721 aaaatgttaa gtttgactat gataatctag cttataaaga taaatttatt ttagataaat
     3781 t
//
LOCUS       DARYSY010000098         3764 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYSY010000098 DARYSY010000000
VERSION     DARYSY010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3764
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(42..623)
                     /locus_tag="TVR04_001889"
     CDS             complement(42..623)
                     /locus_tag="TVR04_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1270550.1"
                     /translation="MRRIRLATLADAKALLDIYHPYVEETAVSFEYTVPSLTEFEQRL
                     SDIMAFYPCLVAEEEGGILGYAYASRFHVRAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASPAHATPYLTNSSQAFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            complement(877..1290)
                     /locus_tag="TVR04_001890"
     CDS             complement(877..1290)
                     /locus_tag="TVR04_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1270551.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAIGLMAVLLSKDIHRLSFGSLI
                     SFAIFAVSTVASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            complement(1952..2155)
                     /locus_tag="TVR04_001891"
     CDS             complement(1952..2155)
                     /locus_tag="TVR04_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1270552.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVIGAIGCASRGVKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(2172..2426)
                     /locus_tag="TVR04_001892"
     CDS             complement(2172..2426)
                     /locus_tag="TVR04_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1270553.1"
                     /translation="MNTILMKQFEIIDADKLAHVEGGKNNWQTNVWEGGTAAVGGWTL
                     GTTICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(2579..2875)
                     /locus_tag="TVR04_001893"
     CDS             complement(2579..2875)
                     /locus_tag="TVR04_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1270554.1"
                     /translation="MSALHWFSGGKARRTEALLLLKELMILLSEQENKQSLYQIIYYF
                     SNELASGGTSVPLVLSELNVALSAIMVKESLQLTKEETQLLKQLRQLSHVHYGY"
     gene            complement(2875..3093)
                     /locus_tag="TVR04_001894"
     CDS             complement(2875..3093)
                     /locus_tag="TVR04_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HEL1270555.1"
                     /translation="MNTTLMKQFEIIDADKLAHVEGGKTTYYGNGLYCNTQKCWVNWS
                     EAVNIILNNSVMNGLTGGNAGWHSGGII"
     gene            3404..>3764
                     /locus_tag="TVR04_001895"
     CDS             3404..>3764
                     /locus_tag="TVR04_001895"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270556.1"
                     /translation="MKLSYNDKIEIYQMRQLGWTWSRLSQKFGVHDSLLKYMIRLIDK
                     HGLEIVHKGKNRYYPPELKKQMINEVLMNGRSKLEVALDYGLPNWGTLVNWIAQYKKN
                     GYTIVEKTRGRAAKMGHQ"
BASE COUNT         1232 a          845 c          635 g         1052 t
ORIGIN      
        1 ggacctaatc cttttgtatt aatctaagct tttataaggt gtcattcaga ctggtgcttc
       61 tggcaaagaa aatctctaaa tgacatcact gggcgagggc gtacgtcatg ctctcccagc
      121 agtttctcca tccaaatcat atcaaaccac tggttaaact tatagcctga ctgatgaaat
      181 ctgccaacca accgataacc gagtttttca tggaaggctt gactgctatt ggtcagataa
      241 ggtgtagcat gcgctggact agcgatacag gcattacaat ttaagattcc catacctttc
      301 agataaccct ccaaacggtg atacaaggct gatcccaagc ctctccctct agcctcctgg
      361 gccagataaa tggtcacctc agcagaccaa gcataggctg cgcgtacatg aaagcgacta
      421 gcataggcat agcctaaaat gcctccctcc tcttctgcca ctagacaggg ataaaaggcc
      481 ataatgtcag acaggcgttg ctcaaactcg gtcaagctag gtacagtgta ctcaaagcta
      541 acagcagttt cctcaacata aggatggtaa atatcaagta aagccttagc atctgctaag
      601 gttgctaaac gaatcctacg cattaatagc cctcctagtt ttcccagtat actccaaaac
      661 aagggccttg tcaaaagcac tgatactaaa aagaaagcct aacccctaaa cgaaataggt
      721 tgtcatatcg cttgcagata gacagctcta ccccctcaaa agctatttta agcgtttgag
      781 cacacaaaca ctaggtatcg ctttaaggct gatacctagt gttatagctt atgattaact
      841 ggttaaggag gtgattccaa gtaccacctc aagctattaa cgacgataag cttttgcgta
      901 tctgatcccc caaatcatca atcccatagt gacaaatgat ataaaagagc atatcacagc
      961 aataacctgc ttataaaact cagacgagct tagaccacaa tagattgaca caatgcctat
     1021 aatcataaac accactataa acaggatctg agttaataac agattgggac gtgtttgttc
     1081 cttcaactgc tcaatcgcaa tttctcgtga aaaatagtaa ttagaagcaa cagtgcttac
     1141 cgcaaagata gcaaaactaa tcagtgatcc aaaagaaagc ctatgaatgt cttttgaaag
     1201 aagaacagcc atcaagccaa tagctggtag ctgaccagtt aaaagcctaa aaatcatcaa
     1261 ataatgtagt cgcttcattt tattaagcat tacagcacct tgccctttct tagcaagtca
     1321 gtgcgccacc tattcctcca atagctgcgt cacaaactct attaattttt tcagcctcaa
     1381 cataagcaag tctaccagta cctaagcatt aaatatttca tcaatgctgt cgttcacatg
     1441 aatacttcct acgtttagca actggcacct gtatagcaga taaacaatcg ctttcagtat
     1501 ttaagtctta aaatgtcgtc gaaacgtctt aaatggtaat acgaaaactg ttgacaccaa
     1561 ttaagcgcat ttctaatacc cgtaacgaat atgcgaaagc tgtcttaatg cttcaaaagc
     1621 tgagattcct ctgaggtctc tctttggcca tcatgctccc ctgataacat ttgaaggcac
     1681 tcctgctaac atatgatagg ctacaggagt atcattcttt aaaggttaac aattgctaaa
     1741 atttcgatat taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt
     1801 catgagctaa aaataacaaa aaaaagcaat ttatcgttga tatatcaaca acgtcattat
     1861 ttttatccaa acctctcaca gatctataga taaagtaaat ttgaaaggta aaaataacta
     1921 tagtaaatat atatttcaga tgcatatcat attatgatga agccttatag gctaaataac
     1981 cacaaacagc cgcacttcca actcctccga taacagctcc ccaaggtcca atcctgcttc
     2041 ctaactttac acccctagaa gcacaaccta tagcaccaat aactgctgca ccggcagggt
     2101 ttcctccaca aatgtcgtta agttcttctt ctttgatctg ataataatga gtcataaaaa
     2161 acctctcttg attaaaaacc acctgttgca cctgttactc ctgcccacaa tgatacgcca
     2221 aatttggctc caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca
     2281 caaatagttg tccctaaggt ccagccacca acagcagcgg tacctccttc ccaaacatta
     2341 gtttgccaat tattctttcc accctcaacg tgagcaagct tgtcagcgtc tataatctca
     2401 aattgcttca ttaatatcgt attcatcgtg aatacctcct gtctttattt tttgtctgtt
     2461 gcaagcaaca aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat
     2521 gtcgtcgaag cgtcttgaat ggtaatacga aaaccgttga caccagttaa gcgcatttct
     2581 aatacccata atgaacatga gaaagctgtc ttaattgctt caaaagctgg gtttcctcct
     2641 ttgtgagctg aaggctctct tttaccatta tagctgacag tgcaacgttc aactcactaa
     2701 gtaccaaagg aactgaggtg cctccagaag ccaactcatt agaaaagtaa taaataatct
     2761 gataaagaga ttgcttgttt tcctgttcag ataagagtat catcaattcc ttcagcaata
     2821 aaagtgcttc tgtccttcga gctttcccac ctgaaaacca gtgtaaagct gacatcagat
     2881 gattccccct gaatgccaac ctgcattccc accggtaagg ccattcatca cagaattgtt
     2941 taatatgata ttaactgctt ctgaccaatt tacccaacac ttttgcgtat tacaatataa
     3001 gccattccca tagtaagtag tctttccacc ctcaacgtga gcaagcttgt cagcgtctat
     3061 aatctcaaat tgcttcatta atgtcgtatt catcgtgaat acctcctatc tttatttttt
     3121 gtctgttgca actgacaaac ccagtatagc agataaacaa tcgctttcag tatttaagtc
     3181 ttaaaatgtc gtcgaagcgt cttgaatggt aatacgaaaa ccgttgacac cagttaagcg
     3241 catttctaat acccataacg aatatgagaa agctgtctta attacttcaa aagctgggct
     3301 tcctcctttg tgagatgaag gctctatact gtaatgtcaa atagccaaac tgaactgcac
     3361 cccaaaagtt agagaataaa tctaactttt gaggtgtttt tctatgaaat taagttataa
     3421 cgataaaatt gaaatctatc aaatgagaca attagggtgg acttggtcac gtctcagtca
     3481 aaaatttggt gtccatgact ctcttcttaa atacatgatc cgtcttattg ataagcacgg
     3541 actagaaatt gttcacaaag ggaaaaatag gtactatcct cccgaactaa agaagcaaat
     3601 gattaatgag gtcttaatga atgggaggtc aaaattagaa gttgctctag attatggttt
     3661 acctaattgg gggacacttg tcaattggat agcgcaatac aagaaaaatg ggtatactat
     3721 tgttgagaaa acaagaggga gagctgctaa aatgggacat caac
//
LOCUS       DARYSY010000099         3649 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYSY010000099 DARYSY010000000
VERSION     DARYSY010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3649
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            164..1216
                     /locus_tag="TVR04_001896"
     CDS             164..1216
                     /locus_tag="TVR04_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1270557.1"
                     /translation="MTLDKHRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWIIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTFLFALCG
                     FPISLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQHLLKWVDKKIPFAD"
     gene            complement(1389..1760)
                     /locus_tag="TVR04_001897"
     CDS             complement(1389..1760)
                     /locus_tag="TVR04_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1270558.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHRQKKA"
     gene            complement(1895..2806)
                     /locus_tag="TVR04_001898"
     CDS             complement(1895..2806)
                     /locus_tag="TVR04_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1270559.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(2822..3631)
                     /locus_tag="TVR04_001899"
     CDS             complement(2822..3631)
                     /locus_tag="TVR04_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1270560.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
BASE COUNT         1058 a          730 c          784 g         1077 t
ORIGIN      
        1 tttcatgcgt ctgtcgcgga gcatcagtag cacaaaagac tgatgacaag taggcttgag
       61 atcagagaga caatagagca agataaaaaa tctaataatc agacaaaatc aaatcgttaa
      121 atattaaaaa ttgtggtaaa ctaatattat gtgtaaaaat gtaatgacat tagataagca
      181 ccgccattac ggtttagatt tattgcgaat catttccatg tttatgattg tgatcacaca
      241 tgttttggga aagggtggct tgcggtcaac tgtcgaaggt gaggcagatt cttattttat
      301 tgttacctgg attattcagg ttcttgttta tggagctgtc aattgctatg cgttgattag
      361 tggctatgtg ggcattaagt cgccctataa atattccaaa atcgttaata tttgggtaca
      421 ggttttcttt tatagctttc tgatgacctt tttgtttgcc ttatgtggct ttccaattag
      481 cttagagaat tggcgtcagg ccctctttcc catagtgagt ggcaattatt ggtatatcac
      541 cgcctacttt gggttactga tttttatgcc tatgatcaat ggtggcctca ataccttatc
      601 caataagcag ctaggccgct tggtactgct ggtttttgct attttttcgt tgatcccagc
      661 tttgatgaac cagcaggtcg atgaattttc cttaagcaag ggctttgaaa tgacttggtt
      721 gattattctc tacattatcg gagcctatct aaggaggata gagctaagca ggtttagtca
      781 taagcttctt attgcggttt atatgggatc tttggtagtt acctatatca tgaaatttat
      841 ggtgggaaat atttggtact ggtatgtatc acctagcctg accttgggag ctattgcctt
      901 atttattctt tttgctaagc tgaagctgac atcagaaaca ctgctgctac gctttattgt
      961 gattgtgtct ccaacgactc taggcattta tctggtgcac ttacacccct tgctggtcaa
     1021 atttattatt cgcgattttg cagagccctt tgtcaatgct cctatccttt tatatccact
     1081 actgatattt ggcgttggca ttgtgattta tttcttgtcc tttctggttg aacaggcaag
     1141 gctgatgctt tttaaaaaac taggctttca acatttgttg aaatgggtgg acaagaaaat
     1201 cccctttgca gattgatgaa gaataaggtt agatttagat tgaagaaagg atttgcttaa
     1261 gcttgttttt caagcttttt ttgttaccaa cgaaaaaaac tcttagacat gttgctatag
     1321 tgctatgtct aagagtgtta gcatgctggg ctatgaccat agtattgagt ggcctatcaa
     1381 tgagattttc aagccttttt ttgacgatga aatagctttg ctattatggt ttggaccaag
     1441 gtcggcagct tgataacctt gtcattgcca attgtttctc tagcaacctt caagattttt
     1501 cctgaatcct ttgaagcaaa gagaaatttg ccttgatcgg taaagatttc aaagtgacga
     1561 ctgacttttt ttccagaaac attggcaccg atttggttaa tggccgtcca gggaatttga
     1621 atgaagtcct caacgttttt atcattgtaa aattccaaag ccttatctcc aagtaagatt
     1681 ttcccaacct ttcctccgat tccaagatag gagacagctg ttgtctgaag gatcaccctt
     1741 tgatttaaag attgtgccat aataagtcct ttattgtttt ttgtttatta taacataaaa
     1801 atatagcttg tagcaggctg aatactggcc tttgctaagg ctctagacag ccaaaaatta
     1861 aggaactggg aagcccccaa ttccttaatt tttattacat gatgtgaaga aggtgtgcga
     1921 tgataccaaa tgcaaacaag gcaatgatga ttgcgattgg tgatactttt ttcttcaata
     1981 accacatgca aaggaaggta agtagtaatc cagcaagtcc tgggatcaat gagtctaatt
     2041 gcccttgaag ggtttgtgat tgaactttat caaggctcat gccacccata gcttgtccaa
     2101 gaatactttt tagctcagca cctttaacgg ctccctcagg gaagacaaca taggcacctt
     2161 cagaaagctg cttgcctgga aggttgatgg taaagttgat agatacccag cgttgtacaa
     2221 ggacagcaag gataaacata ccaaggatag aagctccctt agtgatgtct tgtaggatac
     2281 cacctgacat gtctttggtg atttcagatc cagccttgta gccaaattct tgagtgtacc
     2341 acaagaaggc catacggata atgttccagc caaagaagaa aaggagtgga ccgacaaggt
     2401 taccagtttg tgcaagagaa gcaccaagag caccaaggat aggacgcact gtaaaccaga
     2461 agacaggatc accgatacct gcaagaggtc ccatcatacc gatcttaacc ccttggatag
     2521 cagcgttgtc aatagcagta ccgttggcac gttcttcttc aagggcaagc gttaccccga
     2581 tgataggagc agccacatat gggtgagtgt taaagaattc catatgacgc tcaagtgcag
     2641 cagcacgatc ttctttagtt gtgtaaagct ttttaagtgc tgggataagt gcataagccc
     2701 aacccatgtt ttgcatacgc tcatagttcc aagacccttg aaggaattgt gaacgccacc
     2761 aaacacgttt gcggtcagct tttgttaatt taatttgttc agtcattaat cttacccctt
     2821 tctagtagtc ttctaggata tcgccgattg ggtcagcaga gcctgctcga cctccaccgt
     2881 taccaccttg ttttgaaagg ttaaggtaga taaaggcaat agccacaccg ataacaccca
     2941 tagcgataag tgttaattgg gtcacagctg caagggcaaa accaagtgcg aagaatggcc
     3001 atacctcacg tgtagccatc atgttgataa caagagcgta acctacggca acaaccatag
     3061 caccaccgat ttgcatacct tcattcaacc aagctggcat agccttcaag acactttgaa
     3121 cggcctcagt tggcacagca acaagaagtg cagctggtac agcaatacgc aagccttgaa
     3181 gaagaagtgc agcaaagtgg aagcgctcga tagcagagaa gttaccctct aaagcagcct
     3241 tgtccccagc gtgaacaagt acagttgaaa tggtacgaac aatcatagta aggaaaagac
     3301 ctgcaaccgc aagaggaata gctgttgagt atgcaaaggt aatccctttt tgagtaaagt
     3361 cgccaccctt aaccatgata atagccgctg caacagatgc aagagcagcg tcaggagcta
     3421 cagcagcacc aatgtttgcc caaccaagtg caagcatttg aagagtacca ccaagcataa
     3481 cacctgcttc aaggtgacca gtcacaagtc cgattaaggt acatgcaaca agtggttggt
     3541 gcatttgaaa ttggtccaag ataccttcaa gaccggcaaa gaaggcaacg ataacgacca
     3601 agattgcaga aattaatgaa atatctgaca ttttgttatc ctttcgtat
//
LOCUS       DARYSY010000100         3471 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYSY010000100 DARYSY010000000
VERSION     DARYSY010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3471
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(14..1477)
                     /locus_tag="TVR04_001900"
     CDS             complement(14..1477)
                     /locus_tag="TVR04_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1270561.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPT
                     ALNGTFDPQKGTYIDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGKPKNGEFKTPFVPLLPILAIIICVS
                     FMSQYMVFTWIAFAISTILGIVVYACYGYTHSQERRK"
     gene            complement(1567..>3471)
                     /gene="ftsH"
                     /locus_tag="TVR04_001901"
     CDS             complement(1567..>3471)
                     /gene="ftsH"
                     /locus_tag="TVR04_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1270562.1"
                     /translation="VAGFQYYLRGTSTQSQQISYSKLIKHLKAGDIKSLSYQPSGSIV
                     EVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTALILPSDSVLKEMTSVADKNGTDIT
                     VKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGGGGARGAMSFGKNKARSQAKGDVK
                     VRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARIPAGVLLEGPPGTGKTLLAKAVA
                     GEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGM
                     GGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRSDVLDPALLRPGRFDRKVLVGRP
                     DVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVGADLENVLNEAALVAARRNKTKI
                     DASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEAGHTIVGLVLSNARVVHKVTIVP
                     RGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRVAEEIIFNAQTTGASNDFEQATQ
                     MARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKSYSAQTAQMIDDEVRELLNEARN
                     KAADIINDHRETHKLIAEALLKYETLDAAQIKSIYETGKMPNDPENDEAEVHALSYDE
                     IKDKMTEAKE"
BASE COUNT         1077 a          790 c          601 g         1003 t
ORIGIN      
        1 tagttttgga cttttatttt cttctttctt gcgaatgggt atagccatag catgcataga
       61 ccacaatacc aagtatagtg ctaatagcaa aggcaatcca cgtaaatacc atatactggc
      121 tcataaagct tacgcatata atgattgcta aaattggcaa taacggaaca aagggtgttt
      181 taaactctcc gtttttaggc tttccagcgt tttttcttag cttaatgata gcaaaggaca
      241 tgatgacaag ataagcgaga gtacagatat tgacaaactc agcaagactg gctaggggga
      301 atattcctgc acaaatcata gataatgcac caacaactag ggttgcattt ctaggaattc
      361 ttgttttttc tgtgatttga caaagggctc ttggtaaaag tccatctcta ctgatactgt
      421 aaaccgttct tgctaaggca taggtcattg aaatacaaac tgtaattaga gttaaaatgg
      481 caacaattga gacataatct gctgcccaat ataacccaat actccttaaa gcaaaggcaa
      541 ctgcatcagg tacatctaat tttgtatagt gaacaatccc agttaaaacc attgtaacaa
      601 taacatataa gatcgttaca atcgttaagg ataatacaat acctcttgga attgtttttt
      661 gtggttcttt gacctcatct actgtcatgg aaatagactc aaagcccaag aaagcaaaaa
      721 acatgactga ggctccagcg aaaatacctg acttaccacc ataaatttgg ccaaagccat
      781 aaggcgcaaa atgtgaccag ttggctacat caataaaaaa taaacctaca atgacaaata
      841 aagccagagc tgaaaatttt aatagaacta aaaagctatt gaatcgcaat gctgcctttg
      901 agttcatcaa tacaattgcg gtaaccagga gcattaccaa tactggaagt aagtctatat
      961 aggttccttt ttgaggatca aaggtaccat ttaaagcagt gggcaattgt aagccataat
     1021 tagccagcaa gccttttaaa tagcttcccc agccaacagc tacacttgaa attgctgtta
     1081 aaaattccat gataatatac cagccaacaa tccaagctgg aaattcacct aatgtcgcat
     1141 aaacatagct ataagcccca ccatttgctg gaattcgtga agcaaattca gcataaaaga
     1201 gggctagaat actaatcgca atagcagaaa ggataataga aatggtcaat gccggccctg
     1261 catagttagc tgctcctatg cctgtaatag tgaaaatacc tgttcctacc attgatccta
     1321 agcccaaaaa aatcaaatcc agcattttta agtgcctatt catttcagtc ttattaatag
     1381 cttgcctttt tttacgaaag attgtcatct tgtcactttc tagtcttaaa atagttctac
     1441 ttagtttatc atagttcctg acaattgtaa atttcactaa aatggcccca atatggctta
     1501 aaacctacta aaaaatgagc taggaacgaa gcctaactca tcttaggtaa taacaacaac
     1561 taaacattat tctttagctt ctgtcatttt atctttgatt tcatcatagg acaaggcatg
     1621 cacttctgct tcatcgtttt ctggatcatt tggcatttta ccagtctcgt aaatggactt
     1681 aatttgagca gcatccaacg tttcatactt aagaagtgct tcagcaatca gcttatgagt
     1741 ttcacgatga tcattaataa tgtcagcagc cttgttacga gcttcgttta ataactcacg
     1801 aacctcatca tcaatcattt gagctgtttg ggcagaatat gatttttcag gtgacaattg
     1861 ccctggcatc atagcatgat tgccttcata ttggactggt ccaagttttt cactcatacc
     1921 atactctgtg accatagccc tagccatttg agtggcctgt tcaaagtcat ttgaagcacc
     1981 tgttgtctga gcattgaaaa taatttcttc tgcaacacga ccacccataa gccctgcaag
     2041 ctgctccttc agatcatctt tagataaaag catttgatct tcctttggaa gcgcaatcat
     2101 atagccgcct gctcggcctc gaggcacaat tgttaccttg tgcacaacac gagcattgga
     2161 taagactaaa ccaacaatag tatgacctgc ctcatggtag gcaaccattt cgcgctctct
     2221 ctgtgaaatg ctacgatcct tcttagaagg tcctgcaata acacgatcct ctgcctcatc
     2281 aatatcacta gcatcaattt tagttttatt tcgacgcgct gcaacaaggg ctgcttcgtt
     2341 tagaacattt tcaaggtctg caccgacaaa acctggagtt tgttgagcaa caaccttcag
     2401 attgacatcc tcagcaagtg gcttattttt agcgtggacg cgcaatatag cctcacgtcc
     2461 tttaacgtct ggacgaccga caagcacctt acggtcaaaa cggccgggcc ttaacagggc
     2521 tggatctaga acgtcactac ggttggttgc agcaataacg ataatgcttt cattaccttc
     2581 aaagccgtcc atctcaataa gaagctgatt aagggtttgt tcacgctcat cgttaccacc
     2641 gcccatgccg gcaccacgac gacgaccgac agcatcaatc tcatcaatga aaataatcgc
     2701 tcgctcagcc ttcttagcat cttcaaacaa ggagcgaaca cgactagcac caacaccgac
     2761 aaacatttca acaaagtctg agcctgaaat gctaaagaat ggtactcccg cctctccagc
     2821 aacagccttt gcaagcaatg ttttacctgt tcctggaggt ccctccaaaa ggacaccagc
     2881 aggaatacgc gcaccaagtg ccttgtattt cttaggattc tttagaaaat caacaacctc
     2941 taccagctct tgcttttctt cctcagcacc agcaacatct gtaaatctaa cctttacatc
     3001 gcctttagct tgtgatcgag ccttattttt accaaagctc atggcaccac gagcaccgcc
     3061 accaccttga ttcatgatca tcatcatgaa ggcggcaaaa atcacaattg gcagaaagct
     3121 cataagaaag gtaatccaag ccccacttga gctttcttgt tttacagtaa tgtctgttcc
     3181 atttttatct gcgacagaag tcatttcctt taatacagaa tcagatggta aaattaaggc
     3241 cgtaaattct gttacctcag tggctgcact attacctaaa aatgacaagc ctgtgtcaat
     3301 agacaccttt tgaggttttt catattttcc tttaacctca acaatgctgc cactaggctg
     3361 atagctaagt gatttaatat cacctgcctt caaatgctta attaattttg aatagctaat
     3421 ttgctggctt tgtgtactag ttcctcttaa gtaatattga aatcctgcta c
//
LOCUS       DARYSY010000101         3353 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYSY010000101 DARYSY010000000
VERSION     DARYSY010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3353
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..203)
                     /locus_tag="TVR04_001902"
     CDS             complement(<1..203)
                     /locus_tag="TVR04_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1270563.1"
                     /translation="MPNYAIILAAGKGTRMNSGLPKVLHKVSGLSMLEHVLKSVSALA
                     PQKQLTVIGHQAEQVRAVLGEQSL"
     gene            complement(549..1523)
                     /locus_tag="TVR04_001903"
     CDS             complement(549..1523)
                     /locus_tag="TVR04_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1270564.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTVK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPKTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNLNHP
                     SHRMYDEFVVFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESNS"
     gene            complement(1524..1982)
                     /locus_tag="TVR04_001904"
     CDS             complement(1524..1982)
                     /locus_tag="TVR04_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1270565.1"
                     /translation="MTAEELWSQYQQINPGVGDLAEAWAFGAEPDLLAQLVLEGTKTA
                     TASAYDLYELDHEQLPKEGSYDVILDSRGQAICIIQITKVSLVPFKDVPAEHAYKEGE
                     GDKSLEEWRQLHDAFFRPYFEEAGIPFTEDSLIVLEEFQRVYPEAAKKEK"
     gene            complement(2181..2879)
                     /locus_tag="TVR04_001905"
     CDS             complement(2181..2879)
                     /locus_tag="TVR04_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1270566.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEMVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2872..3108)
                     /locus_tag="TVR04_001906"
     CDS             complement(2872..3108)
                     /locus_tag="TVR04_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1270567.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGEGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          962 a          855 c          645 g          891 t
ORIGIN      
        1 agcgattgct ctcctaggac agcacgcacc tgctctgcct gatgaccgat cactgtgagc
       61 tgcttttgag gggctagggc tgagacactc ttgaggacat gctccagcat gcttaggcct
      121 gataccttgt gcagcacctt gggaagccct gaattcatac gggttccctt tccagctgct
      181 aggataatgg cgtagtttgg cataatgact tcctccgttt gtacatagat catctcatta
      241 tagcacaaat ggccttaatt tgcagaaaaa acaagaatgc tacaatagtc cttagcttca
      301 gacaaactcc cttacctacc ttgattaact ttttaaagca gctagctaga gctgcctgtc
      361 atcgtcaagt atcagtgata agtaaacaaa gcaggcttgc aaacaccctc ctcactatgg
      421 aaaaagcagc taatgctcag ccattgaagg ggctccgagt catcaggagc aagacctgta
      481 tctgatagaa caagaaaggt catcatttct taagacaaac agcactagtc tatagctact
      541 agttgctctt agctattgct ctctagtgaa gctgctgcct gctctaaaac agccatgact
      601 gccttgctgt gctccaaggc ctgctctgcc ctttccatgt ccttattaga gataatatct
      661 gaaaagacaa caaattcatc gtacatgcga tgagacgggt ggttaaggtt gacggtcctt
      721 gcttgctcac ctcgaatggc tagtaaaagc tctggcacag cattaggagc acctaaaaca
      781 gaaagaaagc ctttattccc ctgaatcgta gagacaatct ctgcactgca atccttagcc
      841 ccaatgcaaa cagccttaaa tcgctcataa tccatcagca aaacaccaga ggtgtcaacc
      901 tgccgctcca tattagccag gtattgaacc gttttgggct tgccaaataa gccaacgagc
      961 agatggatat tataaatatt caaatcacgc aaggcccctc cacccttttt aggatcaaag
     1021 gctggtgcaa tctccccacg cttaaaggca tcataacgag aggaatattg agaataattg
     1081 cactccacaa gcttaatctc tcctaactca gtcaagtgat ccttaataaa ttgggtgttt
     1141 ggcaaatatt ggttggtaat agcttctaat aatatcagct gcttagctct tgcaatgctg
     1201 cttaaagcat caagctcctt gactgtcatg gtaaatggct tttcacaaat gacatgctta
     1261 ccagcctcaa gggcttgctt agccacttca aaatgcaaat gatttggggt agcaacataa
     1321 accgtatcca cctcttcatt ttttaggacc tctgctagct gacagctggc ctgttgaatg
     1381 ccaaaggcgt cagcaagcgc ctctgcggtt tcaagactac gaggcgttga aacaattgcc
     1441 atcaagtcta tacttttgat ctcttttaaa acaggcaaaa cctctttgac aatcatgcct
     1501 gtaccaacaa gggctaattt catttatttc tcctttttag cagcttcagg gtaaaccctc
     1561 tgaaactcct ctaacacaat aaggctatcc tctgtaaagg ggatgcctgc ctcttcaaaa
     1621 taaggtctga aaaaggcgtc atgaagctgc cgccactctt ccaagctttt atcaccctct
     1681 ccttccttat aggcgtgctc tgctggcacg tccttgaagg gaacaagact aaccttagta
     1741 atctgaataa tacagatcgc ctgaccccta ctatccaaaa tcacatcata gctgccctct
     1801 ttaggaagct gctcatggtc aagctcgtat aagtcatagg cagaggctgt agctgtttta
     1861 gtgccttcta gcactaattg cgctaataaa tcaggctcag ctccaaaggc ccaggcctca
     1921 gctagatcac caacaccagg attgatttgc tggtattgag accataattc ttctgcagtc
     1981 atgttatcac ctctattgat cgaatcctct agacaggtag gctcctgctg tattaagcaa
     2041 acctcctagg cactaggttt catggaaaaa cttcatcagc tccctcttag cctgtggcga
     2101 gattgcttga tacagctata aactgtcacc ctctgtacag acaagccaga tcttgctagg
     2161 ccttatgtcg atgtgctgtt tcactttaag ctccagccgc cgtcaatttt aacaatttct
     2221 ccctgcatgg cgctagcttt tccagatgcc aaaaacatgg tcagctcggc tatttcttca
     2281 gccctaagcc aacgaccgat aggggtctca tcagctaccc actgggctaa accacctggc
     2341 tcaaagtctg tagctgtcat tgctgtttgc actgcgccag gagcaatgcc aaaaacctga
     2401 atgcctgcct tggcataatc aagcgctagc tgtctggtaa aaccagccag agcatgcttg
     2461 cttgaggtat aggcagctcc gccgccacct gccatgaagc tagcaataga acacatattg
     2521 atgataatac ctgattgagc tgtcagcatc tgtgccaaat agtgacgcgt gatgcggaca
     2581 gctgcaaaaa aattgacctg aaagagagcc tcaaaatcag cctgtgtggt gtcaagcaag
     2641 ggcttatagg catcaagaac gcccgcagta tggcacaaca catcaaccct aggcaccatc
     2701 tcaaaaagct cagctaaatc acctgtaata tctaactgta aaaactgaaa atctcctgat
     2761 aaatcaggct tttttgcctt atcaacccca taaacagtaa agccatttct caaaaacagg
     2821 cgcgcctgtg ccagtcctat gcccgatgac acaccagtga tcagcactcg cttagtcata
     2881 aacctctacc cagtcagtag caagaacatc gcagggagtc ggtgcccaca tggaaaagcc
     2941 ctcgccctct cctgacacgt taatcaaaaa gtaaggcgtc acctcaagtg ccacaccatt
     3001 ttgttcaatg ctgtcaaaca gctgaacata gttttcagcg cctccccagc ccttacgaac
     3061 gtattttttc ttggccttca agcctggcaa aatctcttca aatgtcatga ttgtctcctt
     3121 ttctaagcct acatcacagc atgagctctt ttaacaatca ttataccaat ttactcagct
     3181 tttgtaagct taaagatcac gaaagtcgca aacgtacaag tttgctttgt tttccagata
     3241 agaatgtaat aggttacatt caagaattaa aaaacgggat tatactacaa aaccatttta
     3301 aaaacaaaag ttatatactc caaaataatc atttaagcat tgttttcatg atg
//
LOCUS       DARYSY010000102         3351 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYSY010000102 DARYSY010000000
VERSION     DARYSY010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3351
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(303..1784)
                     /gene="guaB"
                     /locus_tag="TVR04_001907"
     CDS             complement(303..1784)
                     /gene="guaB"
                     /locus_tag="TVR04_001907"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1270568.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAYFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIQELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            complement(1985..3007)
                     /gene="trpS"
                     /locus_tag="TVR04_001908"
     CDS             complement(1985..3007)
                     /gene="trpS"
                     /locus_tag="TVR04_001908"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1270569.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYNMFVFLA
                     DQQALTDHAKESKMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANLVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKAA
                     MGIRYF"
     misc_binding    complement(3063..3301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          981 a          781 c          596 g          993 t
ORIGIN      
        1 taatttaact atttaataat attattttaa catgatttct atatttcaca atatttcatg
       61 tctatttaag ttaatccttt tagggttatg ccatttttgg aaggtattac gcttaagagc
      121 attcagtatg atttgatcat tagcctagca ttgaaatatc acaaagctaa aaagcaaata
      181 gctagggcta gcaagctgtc atttctaatc atggtttaat cgtgcaacaa aaaaagccga
      241 gaaaatatct cagcttttaa aatagatata tcaaatacta catcaagtaa acacctgcag
      301 gattaatgca tggaataatt tggtgcttca tttgtgattt ggacatcatg tgggtgactt
      361 tcaatcagac cagctcctga catctctaca aattgagcat tatcatgcaa ttcttgaata
      421 gtaccagctc cgacatatcc catacctgag cgaatcccac caagcatttg aaagacaata
      481 tcagaggcag ctcccttata agcaacacgt ccttcaatac cttctggcac tagcttgttg
      541 gcttcattaa cagagccttg gaagtaacgg tcgcttgatc cttttttcat agctgcaatt
      601 gatcccatgc cacgataggt tttaaacttg cgtccttgat agatttcagt ctcacctgga
      661 gcttcatctg tcccagcaaa catagagcct agcatgacag cattgccacc agctgcaagg
      721 gcttttacaa tgtctcctga atacttaata ccaccatcag caataatggt tttgccatat
      781 tcacgagcaa cagcagctgc gtcataaata gctgtaacct gaggtactcc gacaccagca
      841 atgacacgag ttgtacagat tgaacctggt ccgataccaa ccttaaccac atcaacccct
      901 gcgtcataaa gggcacgcgc gccttcagca gtagcgatat ttcctgcaat caaggttttg
      961 tcagggaagt aggcgcgaat ctctgcaatt ttcctaagaa cacctgcgga atgtccatga
     1021 gctgtatcaa taacaatagc gtctgcacca gcttcaaata aagcctctgc acgctcaaag
     1081 gtatctgatg taacaccaac cgcagccgct accagcaacc gcccaaactc gtcctttgca
     1141 gcatgtggaa actcaataac cttttcaata tccttgattg taatcaaacc tgaaagacgg
     1201 ccattatcat ctaccaatgg tagcttttca atccgatgct catgaaggat acgctctgct
     1261 gtctcaaggt cagtcccaac ctcagctgtc accagctgct cacttgtcat atgttctgag
     1321 atcggggcgt tgtaatcaga aataaaacgc atgtcacgat tagtaataat cccgactaat
     1381 ttgcggttag ctaaggtctc tacaatcgga acaccactaa tacggtagcg ctgcatcaat
     1441 tcctcagcct cagctacctt gtgctcaggc gttaggaaaa atggatcaat gatcacacca
     1501 ttttcagaac gcttgacctt gcgcacctcc tcagcctgct cagcaattga catgttctta
     1561 tgaataacac caagaccgcc tgcacgcgca atcgcaatag ccattttact gtctgttaca
     1621 gtgtccatag ctgcggtaat aataggaata tttaatgtca aatttttagc aagcttggtt
     1681 tttaaattga cttcatttgg aagaacatga ctttctgccg gaataagcaa aacatcatca
     1741 aacgtgtagc cttttttcaa aaatttagtg tcccaatttg acatcaacac aatcctcttt
     1801 tcttcttttt tagggaatac taccccagcc tatttttatt gttactatca tatcacgcta
     1861 aattcatttg tcaataacat aattctatat atttctgtaa attaaaaaga caggtcttga
     1921 cccatgagtg ataggtgcat ttgaaaagat aagaggccaa gaatcattct cagcctctac
     1981 gctattaaaa ataacgaatc cccatagcag cctttacttc agacaatgtt tgggcagcca
     2041 ctgcctgtgc tttttgactt cctgcttcta gcatacgaaa gacctcgccc ttatccttgg
     2101 cgtattccaa tcggcgttgg cgaattggcg caagctctct ttccaaaata tccagcagat
     2161 aacgcttggt tttaacatct ccaaggccac ctctttggta atgctctttc atcgcttcaa
     2221 tatcagcttt gtcctctttt tggccaaaaa tatctaggta atgaaagacc atattacctt
     2281 ccagctgtcc cggatcctca atccggatat gatttggatc ggtatacata ctcatgactt
     2341 tttgacggac agtgtcagca tcgtcagaaa gatagatgcc attacccagt gatttggaca
     2401 ttttagcatt gccatcaagc cctggtagac gtcctgcctt ttcattttcc gggtaaagac
     2461 cttctggctc aatcaagcag gctgtcttat aggtatgatt aaagcttctt acaatttcac
     2521 gtgtctgctc aatcattggc ctttgatcat taccaacagg aactaaatta gctttgaagg
     2581 ctgtgatatc agcagcttga gaaattgggt aaaccaaaaa gcctgctgga atgctctcac
     2641 caaagccctt ttgtgcaatt tcagttttaa cagttggatt acgctccagg cgagcaagag
     2701 acaccaaatt catatagtac attgttaact ctgcaagctc aggaacctga ctttggataa
     2761 aaatagttga cttacttgga tccaagccga cagaaaggta atccaatgcg acattgaaaa
     2821 tagactcacg aatcatctta gattctttgg catgatccgt caaggcctgc tgatctgcca
     2881 aaaagacaaa catattgtac ttgttttcat tttgcaggct tacacgattt ttgagactgc
     2941 cgacgtaatg tcccaagtgc agctttcctg ttggtctatc tcctgttaaa ataactggtt
     3001 ttgtcatgat ttctccttaa tactgatttt atgacatcaa aaaacctcac gcaaaaggct
     3061 tgcgtgaggg cgtcattaca ataaatacgc ggtaccacct caattagtat ctctaatcaa
     3121 tcaatactat ctcatcttct caactcaaga aattgcacga taaggggtgc cagacctgaa
     3181 agttatggtt tcctctcaaa agatccacta gtccatttca tcttgcttgc tgctagctct
     3241 caccgaccac tagctctcta aaaacaaggg aaagattact catctagttt agggccattc
     3301 tatgatattt taagcaattt gtcaagctgc tgagattttt aagcaatagg g
//
LOCUS       DARYSY010000103         3340 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYSY010000103 DARYSY010000000
VERSION     DARYSY010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3340
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(330..1013)
                     /locus_tag="TVR04_001909"
     CDS             complement(330..1013)
                     /locus_tag="TVR04_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEL1270570.1"
                     /translation="MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGG
                     MNGLVVRAMPDQLWRLVTPIVVHIGFEHFFINTLTLYFVGRMAETIWGSRQFLLLYVC
                     SGIMGNAFIMWLTPDTVAAGASTSLFGLFAAITVLGMGGNSHSLRELGRSYQALIVMN
                     LLLNLFMPNVSIAGHLGGVVGGGLCGVALSNQLPNQAFSSRQRRLAALAYVVIVVGIV
                     SRSFLSLAS"
     gene            complement(1010..1537)
                     /locus_tag="TVR04_001910"
     CDS             complement(1010..1537)
                     /locus_tag="TVR04_001910"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1270571.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LATYLPLPHEYQSYLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RSTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
     gene            2189..3055
                     /locus_tag="TVR04_001911"
     CDS             2189..3055
                     /locus_tag="TVR04_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270572.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAAQLK
                     DLPNPTDRIEYSVWDTNDYKAREYLGDLYDFLKSYLGGLEKQAKTPGPQGPAGPKGEK
                     GEKGDTGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQKGEKGDQGQKG
                     EKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGQKGEKGQRGEQGQKGEKGDQGIQGQ
                     GEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPATGETNHPFFTLAALGVIA
                     SAGMLTLKGKKN"
BASE COUNT         1107 a          781 c          717 g          735 t
ORIGIN      
        1 gctgggtaaa gcattagaaa gcactcaaca gcaaacaaaa taggaactaa gacaaccgtc
       61 ctagaagcat taaaaagcaa cggcagcaaa accgttgctt tttgtctaaa tcaaagatac
      121 acttgcccta gcgcttataa gcttgaagga caaagatctt attgtttttt cctttggttg
      181 gctcaaaaca agtagaagga aaccttagtt ctataggcct agaagcttct gctccagatg
      241 acagagctta gagctcacag cagcactgct acagcgacta tgtcctaacg cactggtaac
      301 tagcaaccag ctatcaccga gagctcctgc tagctagcca aggacagaaa gctacggctt
      361 actatgccta ccacaatcac gacataagcc aaggctgcca gccttctttg ccggctcgaa
      421 aaggcttgat ttggcagctg attggacaag gcaacaccgc atagcccgcc accgacaaca
      481 cctccaaggt gaccagcaat actcacatta ggcataaaca gattgagcaa caggttcatc
      541 acaatcaagg cttgatagga tctgcctagc tctctcaagg aatggctgtt tcctcccatt
      601 cctaagacag taatcgccgc aaaaagacca aaaagagagg tggaagcacc tgctgctacg
      661 gtatctggtg tcagccacat gataaaagca ttccccataa tccctgaaca cacatacagc
      721 agcaaaaact gtcttgaccc ccaaatggtc tcagccatcc gcccgacaaa ataaagggtt
      781 aaggtattaa tgaaaaaatg ctcaaagcca atatgaacca ctataggtgt caccaagcgc
      841 caaagctgat caggcattgc tctgacaaca agaccattca tgccaccaaa tataacaaca
      901 gcataagggt gcgtagcaaa ctggccatag accagctgca ttatcaaaaa aactaaacca
      961 gtcaagccca agaaaaagag tgttatcggg tattttttga tcatcagtct cattggcaat
     1021 acacctcctt cacagcaata tcatgtgcct ctaccacaaa atcctcccac tgacaggcat
     1081 aaatcgtgct aaaggtagcc ccctgataat ccctcaaata acgatcatag tagccaccac
     1141 catagcctat acgatagcct gcagggtgaa aaacaagccc tggcacatga atggcatcaa
     1201 tctccgactt agcaacagct atggtactcc taggctccat aagaccaaaa gccgtctgta
     1261 tcaagtcaca aggatcataa gccacaaaca ccatctctcc acgagaacga gtcttgggca
     1321 caaggatagt cttgccgtcc tgcaaggctc gctcaatcag tagatagctt tgatactcgt
     1381 gtggcaaggg cagataggtc gcaagagtct gcgcctcttg atagctgcta ctagcaacta
     1441 ctgctgccaa tagagctaag tccttttcca gcttatcctc tggggtcatc atggctaggc
     1501 gctgaagcac tagttggcga taatcttttt taatcatgcc catatcataa cacaaagcgc
     1561 tgctactatt caagaatcgg ccacaatcaa ggttctttcc ttagttgtcc taccagacag
     1621 ggcagcagct caatcagtga atgtccttct tacttcttga ggtgagcttg tggtctcatg
     1681 agatcaaaaa attatttttc taggttaaga aaagtttaag ctttatgcta tacaatataa
     1741 ctatcctaaa tagagcggtt cttcaccaga ccgccgggag aatggaatcc ctcgttttcc
     1801 cttttcataa tctcccgggc ctctagtgct tttgcgctag aggtcttttt agctgctgct
     1861 tgtgaggtaa cgctggcaga caggcagtct attatcttct aatgacatta gatatgtgac
     1921 tatcattaaa gcaagcagac acagcatcag atactcttaa aaaaccgctg ctagcagctg
     1981 gtatcttgtt tatgggaatc gtacaatgtc aataatatca atcaaaaatc agacgattag
     2041 gattttgatt aaaaaaaaaa aaaaacgaaa ccaaagattg aaattgatag atagctattc
     2101 ccactctaat agtggacatg ttagaatttc ctttgggaaa ggaagttaca ggaaactaag
     2161 actgtttcta ccacaaaagg agagaaagat gagatacaca ttaaacaaaa acaagcgtgc
     2221 tcgtaactac gggctatgct cagcagctat cgctctagca gcagtagcca gcctaggaac
     2281 agctggcagc gctaaagctg aggaagcagc acaattaaaa gatttaccta atcccacaga
     2341 tcgtatcgag tatagtgtct gggatacaaa tgattacaaa gccagagagt atctcggcga
     2401 cctatatgat ttcctaaaat cttatttagg aggcttagaa aaacaggcga aaacacctgg
     2461 tcctcaaggg cctgctggac ctaaagggga aaagggtgag aaaggcgata ccggtccgat
     2521 ggggcctcaa ggcctaaagg gtgaggacgg aaaagacggc gcacctggag aaaaaggaga
     2581 aaaaggtgat ccgggtatcc aaggccctaa gggggaaaag ggtgaccaag gccaaaaagg
     2641 tgaaaagggc gaccaaggcc aaaaaggcga gaagggtgac caaggccaaa aaggcgagaa
     2701 gggtgaccaa ggccaaaaag gtgaaaaggg cgaccaaggc caaaaaggcg agaagggtga
     2761 ccaaggccaa aaaggcgaga aaggccaacg cggtgagcaa ggtcaaaaag gtgaaaaggg
     2821 tgaccaaggt atccaaggcc aaggcgagca tggacataag ggtcaccatg gaaaagatgc
     2881 taagccatca gcacctaaag cagattctaa atcaacagca aaagctatgg cgccagcagc
     2941 tcaaaagggc acactaccag ctacagggga gacaaatcac ccattcttca cccttgcagc
     3001 ccttggtgtt atcgctagcg ccggcatgct aacattaaaa ggcaagaaaa actaaaccag
     3061 ccattgcacc tttcccctta ggcgatgagc tagtaacagc ttttctcatc tcttcaggca
     3121 gcattgccct aagaagatga cctaagttca aaaagaggct atcaccagcc tctcaaattg
     3181 aaaaaagtcc ttagaaaata atttccaagg gcttttcttt gtataaagtc gtacaataaa
     3241 agaaaaggat tgtacagtgt tatctatatt tcataaagac aaactagact ataatcgtaa
     3301 ctgatacgtt ttttctatgc gctaatttct tcaacctctt
//
LOCUS       DARYSY010000104         3182 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYSY010000104 DARYSY010000000
VERSION     DARYSY010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3182
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>3182
                     /locus_tag="TVR04_001912"
     CDS             <1..>3182
                     /locus_tag="TVR04_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1270573.1"
                     /translation="KEKIKDYLDVMNALKDVIEKQRDDFSDEEIKESQAKLNEVYDNF
                     SKKHGFINSFSNTRALKEDSNFPLVSSIEILDDEDNFKAKSDIFSKRTITKAKVVDHV
                     DTSLEALVLSVSQKGYVDFEYMESITNKDRDTLIGELEGEIFLDIKDTDLINNRMPFE
                     NFNNDDPFHFSYVSADEYLSGNIREKIGYLNSYIGEIENVIDLAPSEKKDALLNELGK
                     LKYQREKLQEVMPEELTASDINVRLGATWIPQKDIEDFTFNLLKTPGYDRWNINVRFS
                     PHTSEWNIEGKSVDSTNDLANMTYGTSRVNAYKLIENALNLKDTKVFDQVINDDGSKT
                     SVLNKKETMLASQKQELIKEEFKNWIFEDPDRRYRLEKIYNEKFNSIRNREFDGSNLT
                     FDGMNTEIRLREHQKNAIARTLYGGNTLLAHVVGAGKTFEMVASAMESKKLGLASKSL
                     FVVPNHLTTQIGREFMQLYPSANIMVADKKDFQPKNRKRFIGRIATGEYDAVIIGHSQ
                     FEKIPMSKEYQVRHIQDQIDDIVSFIDENKRNRGENFTVKQLEKTKKKLLVRLEKLND
                     DFKKDDVITFEELGVDKLFIDEAHNYKNLFLHTKMRNVAGIGQSEAFKSSDMYMKCRY
                     MDEMTGGKGVVFATGTPISNSMTELYTMQRYLQYDDLKARGLEHFDAWASTFGETENT
                     FELSPEGTGYRQKTRFSKFYNLPELMSMFKEVADIKTSDMLNLPVPEANFEVIKTKPT
                     EEQKEILEAISERADAVRNNQVEPTEDNMLKITNDGKKLALDQRLINPLLPDDPNSKV
                     NVCVKNIFSIWDKTKENSSTQLVFSDMSTPKGDGEFNIYDDIRNKLVNMGIPKEEIAF
                     IHEADTDKQKDELFSKVRRGEVRVLLGSTQKMGAGTNVQNKLIALHDLDVPWRPSDLE
                     QRSGRIVRQGNENDKVNIFRYVTENTFDSYLWQTIENKQKFISQIMTSKTPVRVAEDV
                     DEASLSYSEIKALATGNPLIKEKMDLDNEVTKLKMLEANYKSNKYKLEDKVNKIYPQS
                     ILKTEMEIQAVNEDIASVEKLGEGDIKFTS"
BASE COUNT         1281 a          438 c          607 g          856 t
ORIGIN      
        1 caaagaaaag ataaaagatt accttgatgt aatgaatgcc ttaaaagatg taatagaaaa
       61 acaaagggac gatttttcag acgaggaaat aaaagaatca caagcaaagt taaatgaagt
      121 ctatgataac ttttcaaaga aacatggctt tattaactcc ttttcaaaca ctagagcctt
      181 aaaggaagac tcaaactttc ctttggtatc atcaatagaa atacttgatg atgaggataa
      241 tttcaaagct aagagtgata tattctcaaa aagaacaata acaaaggcaa aggtagtaga
      301 tcatgtagat acttcacttg aagccttagt cttatcagtt tcgcaaaagg gatatgtaga
      361 ttttgaatat atggaatcta tcacaaataa agatagggac accttaattg gtgaacttga
      421 gggcgagata tttttagata ttaaggatac agacctaata aataacagaa tgccctttga
      481 aaactttaac aatgacgatc cctttcattt ttcatatgta tcggctgatg agtatttaag
      541 tggcaatatc agagaaaaaa ttggctacct caattcatat ataggagaaa ttgaaaatgt
      601 aatagattta gcaccttctg aaaagaaaga cgcattatta aacgagttag gtaaactcaa
      661 atatcaaaga gagaaactac aagaagttat gcctgaagaa ctcactgctt ctgatataaa
      721 tgtaaggtta ggagcaacat ggatacctca gaaagatatt gaagacttta cctttaacct
      781 cttaaaaaca cctggttacg ataggtggaa tataaatgtt aggttctcac cacatacaag
      841 tgaatggaac attgagggta aaagtgttga ctcaactaat gaccttgcta acatgactta
      901 tggtacaagt agagtgaatg cctataagct aattgaaaat gctcttaatc taaaagatac
      961 gaaggtattt gaccaagtaa taaatgatga tgggtctaag acttctgtat tgaataaaaa
     1021 agaaactatg cttgcaagtc aaaagcaaga attgattaaa gaagaattta agaattggat
     1081 atttgaagat cctgatagaa gatataggct agaaaagatt tataatgaaa aattcaattc
     1141 aattagaaat agagaatttg atggttctaa cttaactttt gatggaatga atactgaaat
     1201 cagacttcga gaacatcaaa aaaatgccat agcaaggact ctttatggag gaaatacact
     1261 gcttgcccat gtagtaggag caggaaaaac ttttgaaatg gtggcttctg ctatggaatc
     1321 taaaaagttg ggacttgcaa gtaaatcatt atttgtagtt cctaaccatc taaccactca
     1381 aattggtaga gagtttatgc agttatatcc gtcagcaaac attatggtgg ccgataaaaa
     1441 agactttcaa ccaaaaaaca gaaaaagatt tattggtagg attgcaacgg gagaatatga
     1501 cgcagttatc ataggacact ctcaatttga aaaaatacca atgtctaagg aataccaggt
     1561 tagacatata caagaccaaa tagatgatat agtttccttt attgatgaga ataaaagaaa
     1621 tagaggggaa aatttcacgg ttaaacaact agaaaagaca aagaagaagc ttttggtaag
     1681 actggaaaag ttaaacgatg actttaaaaa ggatgacgta ataacctttg aagaactagg
     1741 agtagataag ttatttatag acgaagctca taattacaaa aacttattct tgcataccaa
     1801 gatgagaaat gtggctggta tcggtcagag tgaagccttt aagtcttcgg atatgtatat
     1861 gaaatgtagg tatatggatg aaatgacagg tggaaaggga gttgtatttg ctactggtac
     1921 accaatatca aattcaatga cagagcttta tactatgcaa agataccttc agtatgacga
     1981 tttaaaggca agaggattag aacattttga cgcttgggct tctacttttg gagaaacaga
     2041 aaacaccttt gaattatctc cagaaggcac tggatatagg caaaagacaa gattttcaaa
     2101 gttttataac ttgccagaac tgatgtctat gtttaaagaa gtagcagata taaagacctc
     2161 agatatgtta aatttgccag taccagaagc aaattttgaa gttattaaaa caaaacctac
     2221 cgaggaacaa aaagaaatat tagaagctat ttcagaaaga gctgacgcag ttagaaataa
     2281 ccaagtagag ccaacagaag acaatatgtt aaagattaca aatgatggca aaaaacttgc
     2341 ccttgaccaa agattaataa atccactact tccagatgat cctaattcaa aggtaaatgt
     2401 atgtgtaaaa aatatatttt cgatctggga taaaacaaaa gaaaattcat cgacacaatt
     2461 agtgttttca gatatgtcca caccaaaagg agatggagag tttaatatct atgatgatat
     2521 tagaaataag ctagtgaata tgggaatacc taaagaagaa atagccttta ttcacgaggc
     2581 agatacagac aaacaaaaag atgaattgtt ctctaaggta agaagaggag aagtaagagt
     2641 attattaggc tctactcaaa aaatgggagc aggtacaaat gtacaaaaca aactaatagc
     2701 cttacacgat ttagacgtcc catggagacc gtcagaccta gagcaaagaa gtggtagaat
     2761 tgttcgtcaa ggtaatgaaa atgataaggt aaatatcttt agatatgtaa cagaaaacac
     2821 ctttgattct tatttgtggc agacgataga gaataagcaa aaattcattt ctcaaattat
     2881 gacctcaaaa actccagtaa gggttgcaga agatgttgat gaagcaagtc tatcttattc
     2941 agaaattaag gctttagcta ctggtaatcc tttaataaaa gaaaaaatgg atttagataa
     3001 cgaagttaca aagctgaaaa tgctggaagc aaactataag tctaataaat ataagcttga
     3061 agataaggta aataaaattt atccccaaag tattttaaaa actgaaatgg aaatacaagc
     3121 agttaacgaa gatattgcaa gtgttgagaa attaggagaa ggagacataa aattcacttc
     3181 aa
//
LOCUS       DARYSY010000105         3154 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYSY010000105 DARYSY010000000
VERSION     DARYSY010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3154
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            229..1491
                     /locus_tag="TVR04_001913"
     CDS             229..1491
                     /locus_tag="TVR04_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270574.1"
                     /translation="MARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLV
                     TIAVGVAAIVMTAGAATPLVVGAFVAGSGTVAYGVSNLYEAGHNIYLGSVGDGVTVAT
                     NPLRDTLFMGNDRLYHQVGGLFTTASAALIPIGQTKSIAKGLTEFTIGEVGGFIGGQA
                     SYHGTKLLGGSEQDAQRTTLVGNILGGLAASSAARRFSLNELPTSKSFIDGMSPEDSQ
                     RYIQWNKYAKAGLSPSDRVRILEISEKAPKIKLKNGKNRQKLFKKIEATDKEVTRRPD
                     PSSYLAPEYIEAHRRQFDNGAAKFQKFKPNVTYQKGIVGDELGNSFWLSKDHADIIQD
                     IAKGDNRLYETLLGFDEGYLGDGPLYRLDVSPEVISEKGISIPSGNEKGANSWWRPGG
                     RTYPGDMPEGVMKDISTSKGEHTWNVVN"
     gene            1473..1862
                     /locus_tag="TVR04_001914"
     CDS             1473..1862
                     /locus_tag="TVR04_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270575.1"
                     /translation="MERSQLEWEDVSQYEEVKGYGQQVWKHQGIYYLVTNEGGIAEQR
                     VVYELPRELFQLLEQGKRNLGEIAFKLRYDCWPPNISQEEADRLFLRDNPELLENDVD
                     NQKLFTRKELEELLPEGSPILASSDGD"
     gene            1872..2294
                     /locus_tag="TVR04_001915"
     CDS             1872..2294
                     /locus_tag="TVR04_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270576.1"
                     /translation="MGITQMTWEEYETFNKVETPDNLYIREHNGTYYTVFELGIASVR
                     RIFELSAADFEEYLKGLRTADEILFKAQNDCWPPTEEEKRASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYISPLK"
     gene            2534..2959
                     /locus_tag="TVR04_001916"
     CDS             2534..2959
                     /locus_tag="TVR04_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270577.1"
                     /translation="MTENYLPTKESIGYKNIKDILCKVFLINLDSISIREGEDENFAF
                     DFTYGNIEINVVVSATGKSGQFNVGEGGMISIFLPNPNYPISSFLPKQSLESITDDEH
                     FKFKIRHLFGRRQADVEYAMRVLKDYLDSDEAKVLSKNE"
BASE COUNT         1002 a          551 c          793 g          808 t
ORIGIN      
        1 gtggattata gcgagctgat cactgatatc catcgcttgg acgaggccat cattcaatac
       61 gaaagcaatc atgccagtca ggacttatcc gccttcaagg agcttttggc ttcgaccaag
      121 gccttgatag cagaatacag cagtaagccc aagcgggctg ggagctatca ggttggggat
      181 ataggacagc tcaacaccat aaaacgcttt gcgacagcct atcagggagt ggctcgtcac
      241 cttgagacca atgccaagcg tctccaagca gcgcaggagc gggatcatgc tcgttttgag
      301 gcagtagctg cggaggatag ggccaagcag ggctggatag atctagcgct cagccttgtg
      361 acaatagcgg ttggggttgc ggctatcgtc atgacagcag gagcagcaac tcccttggtg
      421 gttggggcct ttgttgctgg cagtggtaca gttgcttatg gggtgtcgaa tctgtatgag
      481 gctgggcaca acatttatct aggtagcgtt ggcgatggag tcacagtggc taccaatccc
      541 cttcgggata ccttgttcat ggggaatgac aggctatacc accaagttgg cgggctgttc
      601 acaacagcca gtgcagccct aatcccgatc ggacagacca agagcattgc caagggctta
      661 acggagttca caataggtga ggttggcggc tttatcggtg gccaggccag ctatcatggc
      721 accaagcttt taggcggcag cgagcaagat gcccaaagaa ctacattggt agggaatatc
      781 ctaggaggac ttgcggcctc aagcgccgct agaaggttca gcttgaatga gctaccaact
      841 tccaaatcgt ttatagatgg catgagtcct gaggatagtc agcgctacat tcaatggaac
      901 aaatacgcaa aggcagggct tagcccgtcg gaccgagtaa gaattctaga aatatctgag
      961 aaggcgccga aaattaaact aaaaaatggg aagaatcggc aaaagctttt taaaaaaatt
     1021 gaagcaactg ataaagaagt tactcgccga ccagatccat caagttattt agctccagaa
     1081 tatatagaag cacataggcg gcaatttgat aatggagcgg ccaagttcca aaaatttaag
     1141 cctaatgtta cttatcaaaa aggaatagtc ggagatgaat taggcaatag tttttggttg
     1201 agtaaagatc atgcggatat tattcaagat attgccaagg gtgataatcg tctctacgag
     1261 acgctacttg gtttcgatga agggtatttg ggagatggcc ctctttaccg attagatgtt
     1321 tcaccagagg ttatttcaga gaaagggatt tctattccaa gtggtaatga aaagggtgct
     1381 aatagctggt ggcgacctgg aggtcgtact tatccgggtg atatgccaga gggagttatg
     1441 aaagatatca gtacaagtaa aggagaacat acatggaacg tagtcaatta gagtgggaag
     1501 atgttagtca atatgaggaa gtcaagggtt atggccaaca ggtgtggaag catcagggga
     1561 tttactatct agtgactaat gaaggcggta tagctgagca gcgagtagta tatgagttgc
     1621 ctagagagct gttccaatta ttggaacaag gaaaacggaa cctaggggag attgctttta
     1681 aattgcgata tgattgttgg ccgccgaata taagtcagga agaagcagat agactctttt
     1741 taagagacaa tcctgagcta ttagaaaacg atgttgacaa tcaaaagctc tttacgcgaa
     1801 aagaactaga ggagttattg ccagaaggta gccctatttt agcgagcagt gatggtgatt
     1861 aaggtaataa catgggaata acgcaaatga cgtgggaaga atacgaaaca tttaacaaag
     1921 tagagacgcc tgataatctt tatatccgag agcataacgg aacatattat actgtttttg
     1981 aacttggtat tgcttctgtt cgccgaattt ttgagcttag tgcagctgat tttgaggaat
     2041 atttaaaagg tcttcgcaca gcagacgaga ttctctttaa ggctcaaaac gactgctggc
     2101 caccaacgga agaagagaaa agagctagtg ataaagcatt tttacaaaga tccccaatag
     2161 ccttaattgc agatccaaca agttgggaac tttttaccca agaagagcta agaaaactga
     2221 ttccaattgc ggagcaaaaa tggatagatt ggaagggaaa gctgccagat gattatatta
     2281 gtcctttgaa ataatgttta agatagcgga gctgtggtta gctctgctag tttaaagcat
     2341 gttcttaaaa gttaatagaa ttagcgacct ataataagga cgggaaagat tttgtattta
     2401 cttctaatcc gtataaggct aaacggatag ccgttgagac gggtatagga aagtcatatg
     2461 ttaacgaatt attactttta cgagaaacag gctataagat agaaaaatat ggacacttct
     2521 ggagggcata tagatgacag aaaactatct tcctactaaa gaaagtatag gttataaaaa
     2581 tattaaagat atattatgta aggtattctt aataaatcta gactctattt ctattcgaga
     2641 aggtgaagac gaaaattttg cttttgattt tacatatggc aatattgaaa taaatgttgt
     2701 ggtcagtgcc accggaaagt ctggacaatt taatgttgga gaaggaggca tgataagtat
     2761 tttcttacct aatcctaatt atcctatatc ttccttctta ccaaagcagt cactagagag
     2821 tattactgat gacgaacact tcaaatttaa aataagacat ctttttggaa ggagacaagc
     2881 agatgttgaa tatgccatgc gtgttttgaa agactatctg gattcagacg aagcaaaggt
     2941 tttatcgaaa aatgagtgag cagtatttac tgataaaagt accaataggc ttaagctaac
     3001 agataagcag ttgggacaag ctttaggatt taggttacaa taggaggagg gtatgggata
     3061 taagattcac tttgaagcca tcagtgccgc ccaacaaagc actcaaacca cgatcagtgc
     3121 ttggggagat gggatgacga gtatccagac cgct
//
LOCUS       DARYSY010000106         3095 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYSY010000106 DARYSY010000000
VERSION     DARYSY010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3095
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..1037)
                     /locus_tag="TVR04_001917"
     CDS             complement(<1..1037)
                     /locus_tag="TVR04_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1270578.1"
                     /translation="MATKADTVLQSYLLQSLNMALGALMQGETSYTNSFNIVIQEDGF
                     IFIPRLPCAYILDDELYNKIFLIASASLYPRYTLLRQNATYFVPLKTDDIHVQRGLFF
                     PWIKGVSERLIISDLDDFAKSLKNNALPIMKNLIIDYNKVTHIAIAGNSGSGKSYVLT
                     YFLSLLKNFSELIIVDPKVDLPARFARKNGIAVIYPQENRSKSDFVSEINESLSTCVN
                     LIQQRQEILLNNPNHQFDHLTIVIDEVLALSEGVNKTIKESFFSLISTIALLGRSSKV
                     HLLLVSQRFDHNTIPVSVREQLNVLIQVGNINKKSTQFLFPDLNPEGIVIPIGHGTGL
                     IQVIDNEHPYQV"
     gene            complement(1037..1351)
                     /locus_tag="TVR04_001918"
     CDS             complement(1037..1351)
                     /locus_tag="TVR04_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270579.1"
                     /translation="MKTNNRKGGYSGNTANEYIDPKQAIVCLSTELEPQTKFEEGQPT
                     GEIIAHKAWFSQKGLPPFQVKFESKVTLPAYMAMIEFENLQACEVGFNVYFKADGLKE
                     VK"
     gene            complement(1488..1973)
                     /locus_tag="TVR04_001919"
     CDS             complement(1488..1973)
                     /locus_tag="TVR04_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270580.1"
                     /translation="MLKAKVKTLYCELLGEAIKQQLLEQEIPQNEVSYYFDDDIRLIS
                     APAISQILKGKRNITLDTVDALQETLGLTNVKSVFFPNVYFCELLISQLTELILTDGS
                     SSTKQLFQAKENDIQQNLSTLTTALYDYFPDFPEEETSYQIAESLAEWLIEFVALVAQ
                     L"
     gene            2289..>3095
                     /locus_tag="TVR04_001920"
     CDS             2289..>3095
                     /locus_tag="TVR04_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270581.1"
                     /translation="MESKNFDYQKLKAVLDEQGVTIEQLAKAIKKEKRTVASWLKGTN
                     TPHKSSLDRILKSLHISERRISKDGVVFFDITEENQQRAEELLYNVLLPFFAYYEANQ
                     LGHEVIKEQKAFNNSGGYDGKSVQFMKPDFIKPSLINEMTNIIESMERFTKRSEFPLK
                     RMKNYDYGFLEDFARDITYIPCDLRERVSYFQNRVEIVPDDVLKSEYARRLLNELDEY
                     ARKDSLMSWQRDGYPSLKITADYNILEFTKKFPALLDAELFQICADILNED"
BASE COUNT         1002 a          479 c          641 g          973 t
ORIGIN      
        1 acttggtagg ggtgttcatt atcaattacc tgaatcaaac cagtgccgtg tccaattgga
       61 atgacgatac cttcgggatt gaggtcgggg aagagaaatt gcgtactttt tttattgata
      121 ttaccgactt ggataagaac atttaactgc tcacgaacag aaacgggtat cgtattatgg
      181 tcaaaccgct gactcacgag caataagtgg actttggaag aacggccgag aagagctatg
      241 gtagaaatga gggagaaaaa tgattctttg atggtcttgt ttacgccttc agagagtgct
      301 agtacttcat cgataacgat ggtcaagtgg tcgaattgat ggttaggatt attaaggaga
      361 atctcctgtc gctgttgaat aagatttaca caagtgctaa gactttcatt gatttcagaa
      421 acaaagtctg attttgagcg attttcttgt ggataaataa cagcaatccc atttttacga
      481 gcaaatcttg caggcaaatc aacctttggg tcaactataa tgagctctga aaagtttttc
      541 aataaactca aaaaataggt aagtacataa gattttccag aacctgagtt tccagcaata
      601 gcgatatgag taactttgtt ataatcgatg attagatttt tcatgattgg aagggcgttg
      661 tttttaagcg attttgcgaa atcatctaaa tctgagatga taagacgctc agagacacct
      721 tttatccatg gaaagaagag tccgcgttga acatggatgt catctgtttt tagagggaca
      781 aagtaagtgg cattctgtct cagaagtgtg tagcgagggt atagagatgc gctagctatc
      841 aagaagattt tgttatagag ttcatcatct aggatatagg cacaaggaag cctagggatg
      901 aagatgaagc catcctcttg aataacgata ttgaagctat tagtatagct cgtctccccc
      961 tgcatcagag ccccaagagc catatttagg ctctggagca agtaagattg caggacggtg
     1021 tctgctttcg ttgccattat ttgacctcct ttagaccgtc agctttgaag taaacattga
     1081 agccgacttc acaggcttga agattttcaa attcaatcat tgccatgtaa gctggaagag
     1141 ttaccttgga ttcaaattta acttggaaag gtggtaatcc cttttgtgag aaccaagctt
     1201 tgtgtgctat aatctctcct gttggttgac cttcttcaaa cttggtttga ggttcaagtt
     1261 ctgtactcaa gcagacaata gcctgttttg ggtcaatgta ttcatttgca gtattgcctg
     1321 aatagccacc cttacgatta tttgttttca tagaattata cctgctttct aattttcttg
     1381 ttactaatct cattttaggt cttgagtatg accgtgttag ctaactacac ttatattcta
     1441 aattatttta tttagtcaca ctttcaagtt ttttgaaagt atagaagtca aagttgtgct
     1501 acaagggcga caaattcaat taaccattca gctaagcttt cagcgatttg ataggatgtt
     1561 tcttcttcgg gaaaatcagg gaaataatca tatagggcag ttgtcaaagt tgagagattc
     1621 tgttgaatgt cattctcttt tgcttgaaag agttgctttg tagagctaga accatcagta
     1681 agaattagct ctgtcaattg gctaatgagt aactcacaga agtaaacatt agggaagaag
     1741 acgcttttta cattggttag tcctagtgtt tcttgcaggg catccacagt atctaaggtg
     1801 atgttacgtt tcccctttag gatttggcta attgcagggg cagaaatcaa tcggatgtca
     1861 tcatcaaaat agtaagacac ttcgttttga gggatttctt gttcaagcaa ttgttgctta
     1921 atagcttcac cgagcagttc acaatataga gttttaactt tagcttttag cattagatgt
     1981 cctttccagt cctcagacgg aaagaaactt ttatgatata ctgctaccga tagttgtgta
     2041 aaaaagcaca ccaaaaaacg gataaacaga tatatgcaag actggactgt tattgtccga
     2101 gtcttcatat ttgtttcaat ccgtccattt gatgcgcatc aactagacta atatatttta
     2161 tttataattc tattttagtg tatttataaa aagatttgga aaagcagaaa agctttcgta
     2221 tcaagggata ggaaatttca atgaaattta aaaaatgaaa tttcatatat atgatgtata
     2281 atagaaatat ggaaagtaaa aattttgatt atcaaaaatt aaaagctgtg cttgatgaac
     2341 agggagttac gatagaacaa ttagcaaagg cgataaaaaa agaaaaaagg acagttgcta
     2401 gctggctaaa aggaacaaat actcctcata aaagttctct agaccgtatt ctgaagtcat
     2461 tgcatatatc agaaaggcgg atttcaaaag atggagtagt cttttttgat attacagaag
     2521 aaaatcagca gagagcggaa gaactccttt ataatgtctt attaccattc tttgcgtatt
     2581 atgaagctaa tcaattaggg catgaagtaa taaaagagca aaaagctttc aataatagtg
     2641 gtggatacga tgggaagagc gttcaattta tgaagcccga ttttataaag ccaagtttaa
     2701 taaatgagat gacaaacatt atagaatcaa tggaacggtt taccaagagg agtgagtttc
     2761 cattgaagcg tatgaaaaac tatgactatg gtttccttga ggattttgct agagatatta
     2821 catatattcc ttgtgatttg agagaaagag tcagttattt tcaaaataga gtagagatag
     2881 ttcctgatga tgttctaaag agtgaatatg ctcgaagact acttaatgaa cttgatgaat
     2941 atgctcgaaa agatagtcta atgagttggc agagagatgg atatcctagt ttgaaaataa
     3001 cagcagatta caatatttta gaatttacta aaaaatttcc agcactacta gatgcagagc
     3061 tttttcaaat atgtgcagac attcttaatg aagat
//
LOCUS       DARYSY010000107         3021 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYSY010000107 DARYSY010000000
VERSION     DARYSY010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3021
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..407)
                     /locus_tag="TVR04_001921"
     CDS             complement(<1..407)
                     /locus_tag="TVR04_001921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270582.1"
                     /translation="MPAKTFNDRLTPEDKEEIKRWDNFLRNDNKAFANANRRDRYHNL
                     GSLDENISIDGRDTDLYELIADTAPSGEEVYFQNEMMAIITNFIEDLEPEDKTIMIGK
                     LTDKPMPSTKLANLLEISDKTVTTHFKKYQKML"
     gene            716..1654
                     /locus_tag="TVR04_001922"
     CDS             716..1654
                     /locus_tag="TVR04_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270583.1"
                     /translation="MNEELQNFFCVKASERIEKIITSRGKSFFEIYSENSNIISWIVS
                     GKRTKRNPYLLTDRAVQRINESVHGQELSDKENRYQCRVISWGDDEEIGDYIPEMMKL
                     IVKNLTDEQQLIFDETLMDDIYFAETIAYTEILNEFNSHFLDVDMEQLYTVDVPISRH
                     LAEMELLEAIEEDFKNEFIKFLDSSKYVRTKVNGKDEYVNKGITFKNQFGCDDIVNLF
                     LRVVNAYKLPIEESIGHRVYSIVKKDVSKLDSLIEEELVYDTVYAPYRQDKIREAEFE
                     FQHGIIKAGQDYIKSLYDTHKSRNETWNKLRKEGEI"
     gene            1706..2989
                     /locus_tag="TVR04_001923"
     CDS             1706..2989
                     /locus_tag="TVR04_001923"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270584.1"
                     /translation="MATKQSKEVKIQREVEKWLTSYGMEFVTQNESVNPEIDKALSKA
                     PSKTGGEGANLVDVKLLLKDSKLDYYPIMIELKWGSNKLEKLDKEDYVANTKTSGKEK
                     GEPNYTNINGYAVNGAVHYANAILQYSSYTDVIAIGITGDEDEAGNLETRFGVYYVSK
                     SNYGIGQKVGEYSDLSFLKPENFDEFTEKVKELQLSEAELRLIHQKREDRIEDALTKI
                     NESLFNKQKNISALARIHLVAASIMANLGVAGKVKPLEPADLKSSDEEGDTDGDILIR
                     KIKAFLKEKNLPRAKQEQILRHLEPTILESSFSYPRNGVSLLKEIFTEVIDDLGYFYK
                     IGVDTDFTGKLFNVMFRWLSFAGDDQNDVVLTPRYVALLMAKLARVNKDSYVWDFATG
                     FRVIIVIEANSYVNIRSSRLLPKFKTQKINSWCAA"
BASE COUNT         1063 a          423 c          615 g          920 t
ORIGIN      
        1 tgcaacatct tttgatattt tttgaaatga gttgttactg tcttgtcgct gatttctagg
       61 agatttgcta gtttggttga tggcatgggt ttatcagtta gtttaccaat cataatagtt
      121 ttatcttctg gttctaaatc ttcaataaag ttggttataa tagccatcat ttcattttgg
      181 aaataaactt cttctccgct gggagcagta tcagctatta actcatatag gtcagtatct
      241 cgtccatcaa tggaaatatt ttcatcaaga cttccgagat tgtgatagcg gtcacggcga
      301 ttggcattag caaatgcttt attgtcatta cgtaggaagt tatcccaacg ctttatctct
      361 tctttgtcct ctggagtaag acggtcgtta aatgtttttg ctggcatatt agcctctttc
      421 taagtcctga gtttgaacag aaagaaacta atatgagcta tactgaatta ccgatagatg
      481 caaaaaggca catcaaataa acggataaac agatatatgc agaactagac ccttatcgtc
      541 tgagttttca tatttgtttc aatccgtcca tttgatgcgc atcaattagg actagttaat
      601 aaattttatt tacaagtttc cttgtatgtt tacagtataa tttatttgat tatgtaaaag
      661 tagtgtattc tgatataata aaattacgca aatacataaa aagaggtcta aaaagatgaa
      721 tgaagaatta cagaattttt tctgtgtgaa ggcttcggaa agaatagaaa aaatcatcac
      781 aagtagaggg aagagctttt ttgaaattta ctctgaaaat tcaaatatca tttcatggat
      841 tgtatcaggt aaaagaacta agagaaatcc atacttactt acagatagag cagttcaaag
      901 aattaacgaa agtgtgcatg gtcaagaact atcagataaa gaaaatagat accaatgcag
      961 agtgatttca tggggagatg atgaagagat aggagattac attcctgaaa tgatgaaatt
     1021 gattgttaag aatttgacag atgaacagca gttaattttt gacgaaactt taatggatga
     1081 tatttatttt gctgagacaa tagcttatac agaaattcta aatgagttca attcccactt
     1141 tttagatgta gatatggagc aactatatac agtagatgtc cctatatctc gacatttagc
     1201 tgagatggaa ttgctagaag cgattgagga agattttaaa aatgaattta taaaatttct
     1261 tgattcatca aaatacgtaa ggacaaaagt aaatggaaaa gacgagtatg taaataaggg
     1321 tattacattt aaaaatcaat ttggttgtga cgatattgtt aatttatttt tgagggttgt
     1381 gaatgcctac aagttaccaa ttgaagaatc aattgggcat agagtatatt ctattgtgaa
     1441 aaaagatgtt tctaaactgg attccttaat agaagaagaa ttagtatatg atactgtcta
     1501 tgctccgtat agacaagaca agattcgtga ggcagagttt gaatttcagc acggtatcat
     1561 taaagctgga caagattaca taaagtcttt atacgacact cataaaagta gaaatgaaac
     1621 ttggaataaa ctaaggaaag agggtgaaat atgatataat tatgtagtgt acaaaatatt
     1681 ttaaaaacta aaatgagaag aaccaatggc aacgaaacag agtaaagaag taaaaatcca
     1741 acgtgaagta gagaagtggt tgacttccta cggtatggaa tttgtgacac aaaatgaaag
     1801 tgttaatcca gagattgaca aagccttgtc aaaagctccc tctaaaacag gtggtgaggg
     1861 agcaaactta gttgatgtca aactgttatt gaaagatagc aagttagact actaccctat
     1921 catgattgaa ttgaagtggg gtagcaacaa acttgaaaag ctggataaag aagactatgt
     1981 tgccaatacg aaaacaagcg gtaaggaaaa gggtgagccc aactatacca atatcaatgg
     2041 ctatgcggta aatggtgcgg ttcactacgc taacgctatt ctgcaatatt ctagttacac
     2101 agatgtaatt gcgattggga ttacaggtga tgaagatgag gcaggcaatc ttgaaacacg
     2161 ttttggtgtt tattatgtct ccaagtctaa ctatggtatt ggtcaaaaag ttggtgagta
     2221 ttcggattta tcctttttaa aacctgaaaa ctttgatgaa tttacagaaa aggtaaaaga
     2281 gctacaacta tcagaagctg aactacgttt gattcatcaa aaacgtgaag atagaattga
     2341 agacgctcta acaaagataa acgaaagtct tttcaacaag cagaaaaata ttagtgcctt
     2401 ggcacgtatt catctagtgg ctgctagtat tatggcaaac ttaggggttg cgggtaaggt
     2461 gaagccttta gaaccagcag atttaaaatc ttctgatgaa gaaggtgata cagatggaga
     2521 tattttaatc cgtaaaatta aggcattttt gaaagaaaag aatctaccac gagctaaaca
     2581 ggaacaaatc ttgcgtcatt tagagcctac gattcttgaa tcgagctttt catacccaag
     2641 aaatggggta tctctcctca aagaaatctt tacagaagtg attgatgact taggctattt
     2701 ctacaaaatc ggagtagata cggattttac agggaagctc tttaatgtca tgttcagatg
     2761 gttgagtttt gcaggagatg accaaaatga tgtggtatta actcctcggt acgtggcact
     2821 gctgatggcg aaactagcac gagtaaataa agattcctat gtctgggact ttgcgactgg
     2881 gtttcgtgtc ataatagtga tagaggcaaa tagttatgta aatataagga gttcaagact
     2941 tctaccaaag tttaaaactc aaaaaataaa tagttggtgt gctgcttaga gtatccattt
     3001 taacaatgga tattgtaaat a
//
LOCUS       DARYSY010000108         2846 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYSY010000108 DARYSY010000000
VERSION     DARYSY010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..2422)
                     /locus_tag="TVR04_001924"
     CDS             complement(<1..2422)
                     /locus_tag="TVR04_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase/lanthionine synthetase C family
                     protein"
                     /protein_id="HEL1270585.1"
                     /translation="MISLIRRNTMQYEFNLDNPLFFVNSEDSVDTSKKYSVVLPYDWH
                     EVANNTEWVTQYPMNHIIDRQGWKVHISATFEDSHEILDIVAQVCHEFLVTFKHLSTE
                     KRFILRNSKIANRGYSGKFITCYPGLEILEDFLNSLEQRLKDFSGPYILSDKRWERAP
                     IYLRYGVFRDAIPNQEEPLKIDELLISGKSVKDSREPRFVVPEGIALPVFLKKWLEDS
                     EQTESQDFPFVIKSAIRFSNSGGIYRAHLKEANKEVILREVRPYTGLDFDGKYSSDRL
                     TAEESALIKLKDMYSVPNVLWSGTVWEHRYLAVDKMKGIPLNRWVTKNYPIYDFAAGD
                     KKYLSRIYSILTELISLVEEAHSRNVFHQDIHLANILIDENDNVSLIDWEQARFDDTN
                     KVEQQAAALGFGSWINDFPSQIDWYGVKQVAHYLFFPLLEQSAFVCGYELQLLKHAKE
                     LFTRLDFPQNDIDAVERTIEYLDQKVTPVRNLTTKKIVKPFNDSIEFCNQLDVLEYYN
                     KLVRGLYVAYNEWNRTSKGDRKFPVHYYGLDINQGIAYSDLGILWGYRELVTLLQEED
                     ALQGEFFHLKQAIIQKTISSFDNDKFSPGLFDGIVGSIWIIYKLGEIDLAKKLFVEHF
                     NSLLNQCESKNLYSGGAGILLVGIYMLSKGLDDELIENKIIEKLELFSREYQKNPNSF
                     CPVGKSETQSNDPYQNTGGLLYGHLGLGWLFGEAFRYTHNELYKECLNLAILTELEAY
                     DLDRMGSLQYHQGNRLLPYLSTGSAGMLLVIVRNSQFLDGELLNIQDKLEKAVDSNFC
                     VFPGLFNGL"
     gene            complement(2444..>2846)
                     /locus_tag="TVR04_001925"
     CDS             complement(2444..>2846)
                     /locus_tag="TVR04_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1270586.1"
                     /translation="YQNVHYFDMTLRDNITMGVSNISDEQLSLVLEKFGLLHELGTNC
                     LDRNYKDQLSGGQKQRVAIIRAIIHKGKILLIDEATSSVDRETSSKIRTFFSEFEGTV
                     VEVAHNYTEEIDDYYTHVIEIKDGVVRLSVV"
BASE COUNT          924 a          568 c          355 g          999 t
ORIGIN      
        1 ataatccatt aaataatcca ggaaatacac aaaaatttga atctacggct ttttctaact
       61 tatcttgtat attgagaagt tcaccatcta gaaattggct atttcttaca attactaata
      121 gcattcctgc acttcctgta gataaatatg gaagtaatct atttccctga tggtattgta
      181 aggagcccat tctatctaaa tcataggctt ccaattcagt tagaatagca aggtttaaac
      241 attctttata cagttcattg tgagtatatc taaaagcttc accaaataac caccctaagc
      301 ctaaatggcc gtatagcagt cctcccgtat tttgataagg atcattactc tgagtttcac
      361 tttttccgac tgggcaaaaa gaattcggat ttttttgata ttctcttgaa aacagctcta
      421 gcttttcaat tattttattt tcaattaatt catcatcgag ccctttagaa agcatatata
      481 tacctaccaa tagaatacct gcaccaccac tataaagatt tttgctctcg cattggttaa
      541 gcaatgaatt aaaatgttca acaaataatt ttttagctaa atcaatttca cccaatttgt
      601 aaataatcca aattgaaccc acaattccat caaataaacc tggtgaaaac ttatcgttat
      661 caaaacttga tattgttttt tgtataatgg cttgttttaa atggaaaaat tcaccttgca
      721 aagcatcttc ttcttgaagt agtgtaacta attctctata gccccataat atccctaaat
      781 cagaatacgc aattccttgg tttatatcca agccatagta atgtacagga aattttctat
      841 ctccttttga agtacgattc cattcattgt aggcaacgta aagtcctcga actaatttat
      901 tataatactc caatacatct aattgattac aaaattcaat agaatcatta aaaggtttaa
      961 caattttttt agttgttaaa tttcttaccg gagtaacctt ttgatccaaa tattcaatcg
     1021 ttctttctac agcatcaata tcgttttgcg gaaaatctaa acgggtaaat aattcttttg
     1081 catgcttcaa aagttgcagt tcatatccac aaacaaatgc agattgttct agtaatggga
     1141 aaaaaagata atgagcaact tgttttactc cataccaatc tatctgactc ggaaaatcat
     1201 taatccaaga tccaaatcct aaagctgctg cttgttgttc aactttgttc gtatcatcaa
     1261 accgtgcttg ttcccaatct attagtgaca cattatcgtt ctcatcaatt aaaatattag
     1321 caagatgaat atcttgatga aacacatttc tggaatgtgc ctcctccacc aaagaaatta
     1381 attcggtgag tatgctataa atcctagata agtatttttt atcacctgct gcaaaatcat
     1441 atattggata gttttttgtt acccatctat taagtggtat ccctttcatc ttatcaacag
     1501 ccaaatatct gtgttcccaa actgtcccac tccaaagaac attaggaaca ctgtacatat
     1561 cttttagctt gattagtgct gactcctcag cagtcaatct atcagaagaa tacttaccat
     1621 caaaatctaa tccagtatac ggtctaactt ctcttaaaat cacctcttta tttgcttctt
     1681 ttaaatgtgc tctatatata cctccactat ttgagaacct aatggcagat tttatcacaa
     1741 acgggaaatc ttgagattct gtctgttcag aatcttccaa ccattttttc aaaaaaacgg
     1801 gaagtgctat accttctgga actacaaatc gaggttctct cgaatcttta acagattttc
     1861 ctgaaattaa caattcgtct atttttaatg gctcttcttg attgggtatt gcatccctaa
     1921 aaaccccata tctcaaataa atcggagccc tttcccatct tttatcactt aaaatatacg
     1981 gcccagaaaa atcttttagt ctttgttcca aagaattcaa aaaatcctct aatatttcta
     2041 atccgggata acatgttatg aacttacccg aatatcccct atttgcaatt ttactattcc
     2101 ttaagataaa tcttttttct gtacttaaat gtttaaaggt tactaaaaat tcatggcaaa
     2161 cttgagcaac aatatcaagt atttcatgag aatcttcaaa agtagcactt atatgtactt
     2221 tccatccctg cctatctatg atatgattca tcggatattg agtgacccac tcagtattat
     2281 tagccacttc atgccaatca taaggtagta ctaccgaata ctttttagat gtgtcaaccg
     2341 aatcttcaga atttacaaaa aataaaggat tatctaaatt aaactcatac tgcatagtat
     2401 ttctccttat taaacttatc atcctataag ttaattgttt ttattaaaca actgataacc
     2461 tcacaacacc gtctttgatt tctatcacat gtgtataata gtcatctatt tcttctgtat
     2521 agttgtgtgc aacctctaca actgttcctt caaattctga aaaaaaagtc ctgatttttg
     2581 atgacgtttc tcgatctact gaagaagttg cttcatctat caataatatt tttcctttgt
     2641 gtattatggc tcttataata gcaactcttt gtttttgtcc acccgacaat tgatctttat
     2701 aatttctatc caaacaattt gttcccaatt catgcaacag tccaaacttc tcaagaacta
     2761 gactaagttg ctcatcagaa atattagaca ctcccatcgt gatattatct cgcagtgtca
     2821 tatcaaaata atgaacattt tgataa
//
LOCUS       DARYSY010000109         2779 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYSY010000109 DARYSY010000000
VERSION     DARYSY010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2779
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..890
                     /locus_tag="TVR04_001926"
     CDS             <1..890
                     /locus_tag="TVR04_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004838467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1270587.1"
                     /translation="ISFLAFSQIKLAGSATTSLRVVSGSIEQTKKLEKFPQMDIDGKD
                     IKPTTFDISFDNVEFSYSGKKILDDISVKIPQNQMTAIVGPSGAGKTTFCNLIARFWD
                     VEKGEISIGKHNIKEYSLESLMRQISMVFQNVYLFQDTIENNIKFAKPDATHEEVIEA
                     AKKACCHEFIMKLPEQYETVIGEGGASLSGGERQRISIARAMIKNAPIIIFDEATANV
                     DPENEDKLQVAMEELTRNKTVIMIAHRLKTIKNANQILVLANGKINQKGTHEELIQAE
                     GIYKNFVEARQKAVNWKLS"
     gene            971..1552
                     /locus_tag="TVR04_001927"
     CDS             971..1552
                     /locus_tag="TVR04_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000715596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1270588.1"
                     /translation="MKKGLSAKDLINVGIYTAIYLVLFFVIGMMNAIPILYPAIYLLI
                     PIVTGIPFMLFLTKVEKFGMVTIMSIIIGVFWYFMGYTWLALVGYIPFGIISDLVMKS
                     GGFKSFKKNVIGFWLFSCGMIGCQMPMWVMADTYMEGVKQQMGEQYALALAKYMPSWM
                     GIAAFGIIFIGSVIGANLGRKMLKKHFERAGII"
     gene            1552..2286
                     /locus_tag="TVR04_001928"
     CDS             1552..2286
                     /locus_tag="TVR04_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1270589.1"
                     /translation="MEEYEVYKPNKPKGFFLDPRTKILFMIFITTIMSVGYKDILVSL
                     ISAIVAIALLLSNKQFKISFIYGGLFTLAIMAHFTKDMYTLPTLINTISVLLNALILR
                     LFPIFMLGYYVVMSTKTSEFIAAMVKWKIPNAFIIPTAVAFRFIPTLKEEHNSIKTAM
                     KMRGISFKNKKAWKNPSLYLEYVTIPLIVSIAKIGDELSAAAISRGLGALKKRTTVVK
                     VKFTIYDLLILLFSIAFTGLFLYRRG"
     gene            2289..>2779
                     /locus_tag="TVR04_001929"
     CDS             2289..>2779
                     /locus_tag="TVR04_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270590.1"
                     /translation="MIEFKDVSFTYDSGNKNAGIFNINLNINAGEVVVFCGESGCGKT
                     TISRLINGLIPGYYSGNLTGSVIVKGHEISKNSINELSQYVGSVFQNPRTQFFNVDST
                     SEIAFACENFGISREEICKRIGKVTKELNIKNLLDKNLFSMSGGEKQKIACASAAAME
                     PEI"
BASE COUNT          983 a          355 c          546 g          895 t
ORIGIN      
        1 taatttcttt tcttgctttt tctcaaataa aattggcagg aagtgcaaca acctctctca
       61 gagttgttag tggatctatt gagcaaacaa agaagttaga gaaatttcca cagatggata
      121 ttgatggaaa agacataaag cctactactt tcgatatttc ttttgataat gtagagtttt
      181 cttattcagg caaaaaaatc cttgatgata tttctgtcaa gataccacaa aaccaaatga
      241 cagctatagt tggaccttca ggagctggaa aaactacatt ttgcaatttg atagcgagat
      301 tttgggatgt agaaaaagga gaaatcagca taggtaaaca taatattaaa gaatattcat
      361 tggagtcatt aatgagacaa attagtatgg tttttcaaaa tgtttattta tttcaagaca
      421 ctattgagaa caatataaag tttgccaagc cggatgctac acatgaggaa gttatagaag
      481 ctgcaaagaa agcgtgttgt catgaattta ttatgaagct tcctgaacaa tatgaaacag
      541 ttataggaga gggaggtgca agtttatctg gtggagaaag acaaagaata tcaattgcaa
      601 gagcaatgat aaagaatgca cctattatta ttttcgatga agctactgca aatgtagacc
      661 ctgaaaatga ggataaattg caggttgcta tggaggaact cacaagaaat aaaacagtaa
      721 taatgatagc acacagacta aagacaataa aaaatgcaaa ccaaatactt gttttagcaa
      781 atggaaaaat aaatcaaaaa ggcacacatg aagagctaat tcaagcagaa ggtatctata
      841 aaaattttgt tgaggcacga caaaaggcag ttaattggaa actgtcataa gtgaaaatga
      901 tttatatgag aattattcaa atatagctca tgtagattta tattatttta atttaaggag
      961 gattaaaaaa atgaaaaaag gattgtcagc taaagatcta atcaatgtag gaatttatac
     1021 agctatttat ttagttctgt tttttgtaat agggatgatg aatgcaatac ctatcttata
     1081 cccagctatc tatcttctaa ttcctatagt cacaggaatt ccctttatgt tgtttttaac
     1141 taaagtagaa aaatttggca tggttacgat tatgtcaatt attatcggtg tgttttggta
     1201 ttttatgggc tatacatggt tagcgttagt tggatatatt ccatttggaa ttatcagtga
     1261 tctggttatg aaatcaggtg gttttaagag ttttaaaaag aatgttattg gattttggct
     1321 attttcttgc ggaatgatag gttgtcaaat gccaatgtgg gtaatggcag atacctatat
     1381 ggaaggtgtt aagcaacaaa tgggagaaca atatgcactt gcactcgcaa aatatatgcc
     1441 ttcttggatg gggattgctg catttggaat tatttttatc ggctcagtta ttggtgcaaa
     1501 tttagggagg aaaatgctta agaaacactt tgagagagcg ggtatcattt aatggaagag
     1561 tatgaggtat acaaaccgaa taaaccaaag ggctttttct tagatcctcg tactaaaatt
     1621 ttatttatga tatttataac aaccataatg tctgtcggat ataaggatat tttagttagc
     1681 cttatatccg ccattgtggc aatagcatta ttattatcta ataaacaatt taagatatct
     1741 ttcatttatg gagggctatt tactttggct attatggcac actttacgaa agatatgtac
     1801 acattgccta cactcataaa tacaatttca gtattgttga atgccttgat tttaagacta
     1861 tttccaattt ttatgttggg ctattatgtt gtaatgtcca caaaaacgag cgagtttata
     1921 gcagccatgg taaagtggaa aattcccaat gcgtttatta ttccaacagc agttgcattc
     1981 aggtttattc caactttgaa agaagaacac aactctatta agacggctat gaaaatgaga
     2041 ggaattagtt ttaaaaataa aaaggcgtgg aaaaatccaa gtttatactt ggaatatgta
     2101 acaatacctt taatcgtttc tattgcaaaa ataggtgatg aattgtcggc ggcagcaata
     2161 agtagaggat tgggagcttt gaaaaagaga actactgtag taaaagtaaa gtttactata
     2221 tatgatttgc tcattttact cttttcaatt gcctttacag gactattttt atataggagg
     2281 ggatagcatt gattgaattt aaagacgtgt catttactta tgatagcggg aataagaatg
     2341 ctggaatttt taatattaat ttaaatatca atgctggaga agtagttgta ttttgtggtg
     2401 agtccggttg cgggaaaact acaataagta gattgataaa tgggttaatc cccgggtatt
     2461 attccggaaa tttgactggg agcgttattg taaagggaca tgaaatttct aaaaactcta
     2521 ttaatgaatt gagtcaatat gtaggatcag tatttcaaaa tccaagaact caatttttca
     2581 atgtagattc aacaagtgaa attgcattcg cctgtgaaaa ttttggaatt tcaagagaag
     2641 aaatttgtaa aagaattggc aaggtaacaa aagaattaaa tataaaaaat ttgcttgata
     2701 agaacttgtt ttctatgtca ggaggagaaa aacaaaaaat tgcttgtgct tctgctgctg
     2761 ccatggagcc tgaaatcta
//
LOCUS       DARYSY010000110         2653 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYSY010000110 DARYSY010000000
VERSION     DARYSY010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2653
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..834)
                     /locus_tag="TVR04_001930"
     CDS             complement(<1..834)
                     /locus_tag="TVR04_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1270591.1"
                     /translation="MIQTNSNHFSFKAAIYCRLSKDDEQKGESASIQNQKELLENYVK
                     SRGWSIYDVYIDDGYTGLNTNRPSFQRLIRDIENKKVDIVITKDLSRLGRNYLQTGYY
                     TENFFPKNNVRYIALNDGVDTFQENNEIVPFKNVLNEFYSRDVSKKMKSAYMTRARQG
                     KFIGCLAPIGYRKDNDDPHKLVIDDETSWIVEKIFDLAFSGYGVQAIRRRLFEEKIPT
                     PTWWNRKKGLRNKKTKLEMTVDGGEYWWDCTTLKEIIENPVYIGHIASQKVNYKFKVG
                     WL"
     gene            complement(838..1062)
                     /locus_tag="TVR04_001931"
     CDS             complement(838..1062)
                     /locus_tag="TVR04_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002839462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270592.1"
                     /translation="MTKRQTKYIVKRNYDNRRTDTDAFLRLIKKSSKLNKTNEIEYNK
                     YNIDSNKKECYNKNSFRESCVISENSNKEE"
     gene            complement(1217..1918)
                     /locus_tag="TVR04_001932"
     CDS             complement(1217..1918)
                     /locus_tag="TVR04_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HEL1270593.1"
                     /translation="MADKRMFSLKIVDSDLFLDMPLSSQCLYFHLSMRADDDGFVNNP
                     KKIIKIIGANEDDLKILIAKGFVIVFDQGIIVITHWKINNYIRKDRYKPTMYIEQKQQ
                     LYQTENGAYISEEKVGCHLVNQRLSSGQPSIDKGRLDKVSIDKGREEQSTPIFYGEFK
                     NVSLSEEEYKNLKEKLNSHTEIMINKLSRYMKSSGKTYQNHYATILKWYEEDKDKLRH
                     QGGNKKMNYDVGESL"
     gene            complement(2002..>2653)
                     /locus_tag="TVR04_001933"
     CDS             complement(2002..>2653)
                     /locus_tag="TVR04_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009220337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HEL1270594.1"
                     /translation="NKAFFFISKTLENSWSRAVLLNFLDTDLFERQGKAITNFTNNLP
                     ATQSDLANEMTRDPYNFDFIAIRQNYDEKELKDALMDNIQKFLLELGTGFSFVGREYR
                     LVVGNSEEFIDMLFYNIKLHCYVVVEVKISAFKPADIGQLGTYVTSVNHILKGDGDNQ
                     TIGLLICKTKDNVLAKYASESSREPIGISEYHLQNLIPESLKGALPTIEEIENELK"
BASE COUNT          741 a          491 c          317 g         1104 t
ORIGIN      
        1 taaccaacct actttgaatt tataattaac tttttgacta gcaatatgac caatataaac
       61 tggattttca ataatttctt ttagggttgt gcagtcccac caatactctc caccatctac
      121 ggtcatttct aacttagttt ttttatttct aagtcctttt tttctattcc accaggtagg
      181 cgtaggtatt ttttcttcaa aaagtcttct tctaattgct tgtactccat aaccactaaa
      241 agcaagatca aaaatttttt caacaatcca tgaagtttca tcatcgatta ctaatttatg
      301 tggatcatca ttgtctttcc tatatcctat tggagcaaga caaccaataa attttccttg
      361 ccttgccctt gtcatatagg cagatttcat ctttttagaa acatctcttg aataaaactc
      421 gtttaaaaca tttttaaaag gaactatttc gttgttttct tgaaaggtat ctactccatc
      481 atttaaagct atatatctga cattgttctt tgggaagaaa ttttctgtat agtatccagt
      541 ctgcaaatag tttcttccaa gccttgataa gtccttagtg atgactatat ccactttttt
      601 attttcaata tctctaatta gtctttgaaa tgatggtcta tttgtattta atccagtata
      661 tccatcatct atatatacat cgtaaatact ccaacccctt gattttacat agttttctaa
      721 aagttccttt tggttttgta tgctggcact ctctcctttc tgctcatcat ctttagatag
      781 tctgcaataa attgcagctt tgaatgaaaa gtgatttgaa tttgtttgta tcatttccta
      841 ttcctcctta tttgagtttt cggaaataac acaactttct ctaaaactat ttttattata
      901 gcactctttt ttattactat caatattata tttgttatac tcaatttcat tagtcttatt
      961 taatttgctt gattttttta ttaatcttag aaaagcgtct gtgtctgttc ttctattatc
     1021 ataatttctt tttacaatat attttgtttg tctttttgtc atagcttatc ctttcatgca
     1081 ataaaaaaaa ggcgattaga ttttcaattt tctaatcacc ttttaagtgt catatttaca
     1141 tttttattat ctctggcata cttttatacc tttttatact taaagtcttt aataatgcct
     1201 ttccacctct ttttatctat aaagattctc ctacgtcata gttcattttt ttatttccac
     1261 cttgatgtct tagtttgtct ttatcttctt cataccattt taagattgtc gcatagtggt
     1321 tttgataggt cttgccacta cttttcatgt atcttgatag tttatttatc attatttctg
     1381 tgtgtgagtt tagtttttct ttaagatttt tatattcttc ttcgcttaga cttacatttt
     1441 tgaattctcc ataaaaaatg ggggtggact gttcttctct ccccttatct atactaacct
     1501 tatctaatct acccttatct atactgggtt gaccacttga caacctttgg ttaaccagat
     1561 gacaaccaac tttttcttct gaaatatatg ctccattttc cgtttgataa agctgttgtt
     1621 tctgctctat atacattgtt ggcttatatc tgtcttttct aatatagtta tttatcttcc
     1681 aatgagtaat gacaataatt ccctgatcaa agactattac aaagcctttg gcaataagta
     1741 tttttaggtc atcttcatta gctccgataa ttttgatgat tttcttagga ttatttacaa
     1801 aaccatcatc atctgccctc attgataaat gaaaatatag gcattgacta cttagtggca
     1861 tatccaaaaa taagtcgcta tccactatct ttagtgaaaa cattctttta tctgccatgc
     1921 tctcctacct ttcttcaaat aaaaaaaaga cgatagtttt tacttctacc gccttacgta
     1981 catttattat gtttttaaaa tttattttag ttcgttttca atttcttcta tggttggtaa
     2041 tgctcccttt aaactttcag gaattaagtt ttgtagatga tattctgaaa ttccaatagg
     2101 ctctcttgag ctttcagaag catattttgc caatacatta tcctttgtct tacagattaa
     2161 aagacctatt gtttgattat ccccatctcc ctttaatata tggtttacag atgttacata
     2221 ggttccaagt tgtcctatat ccgcaggttt aaatgcggaa attttaacct ccacaactac
     2281 atagcaatgt agcttaatgt tgtagaataa catatcaata aattcttctg aatttccaac
     2341 tacaagtcta tattctctgc ctacgaacga aaaacctgtc cctagctcca ataagaattt
     2401 ttgaatatta tccatcaaag cgtcttttaa ttctttttca tcataatttt gccttatagc
     2461 tataaagtca aaattatacg gatctcttgt catttcatta gctaaatcac tttgggttgc
     2521 aggcagatta tttgtgaaat ttgttattgc ttttccttgt ctctcaaaca gatctgtatc
     2581 caagaaattt aaaagcacag ctctactcca gctattttct aatgttttag atataaagaa
     2641 aaatgcttta ttc
//
LOCUS       DARYSY010000111         2615 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYSY010000111 DARYSY010000000
VERSION     DARYSY010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2615
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            171..1916
                     /locus_tag="TVR04_001934"
     CDS             171..1916
                     /locus_tag="TVR04_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270595.1"
                     /translation="MKQKSPAAILWELAKKEHSKLKTSVFIASIGVIAGIVPYIAASR
                     ILVELLKGNEDFKIYSLWLGIGLLSYILKSFLYSMALSVSHKATFSVLKDVRLRMLEK
                     LPKMPLGEIISVPSGNFKQIIVDQVESMEKPLAHLLPEMTSNLLGSLSIFIYLLFLDW
                     RMALLSLISIPVGMLFMGLVMKNYAVQYEGSVKVNREMNSAIIEYVNGIEVIKTFNQD
                     KRSYAKYKDKVIANARYFYEWMKSCQLPVSLSKNISPTTMITVLPFGWYFYISGSLSA
                     EVFISVIILSLGIAGPLLETINFVDGLAKIGTIANSINLILEGKEQKHSDREVTIQQY
                     NIDLQNVKFGYEEEKEILHGISLNIKEGTTVAFVGPSGSGKSTLAKLIAGYWDITEGN
                     INIGGYNLNEIPLKQLYSLTAFVSQDNFLFNESIRENIRMGNPSASDKEVEDIAKKSG
                     CHDFIMKMEHGYDTVVGSSGSHVSGGERQRISIARAMLKNAPIVILDEATSYIDPENE
                     VIIKQALSKLIKDKTVIIIAHRLSTITDAEQIFLIENGKLVSYGKHDELLKGCELYRN
                     MWNAHIGTKDGGMKC"
     gene            1910..>2615
                     /locus_tag="TVR04_001935"
     CDS             1910..>2615
                     /locus_tag="TVR04_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004838467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270596.1"
                     /translation="MLSALKKILDFSGDEKKNVYHSIWVSFLFAIFHMLQISAIYFIV
                     KAIVQKDMSMMPAWIALILLVISIIGRSVTNYFSQLQQCHASYFMVANKRVAIGEMLK
                     KIPMGFFNENNIGEVVGISTTVLEDVENTAAMVMVNTLSGFINTIIFTIMILAFEWRI
                     GFIVAIGCLLYLFVLSKMESKSRSVLPKRQKASAKLVDAILEQIGGMSVIKSFNLTGK
                     GDEKVRGAIENSRKINL"
BASE COUNT          926 a          316 c          521 g          852 t
ORIGIN      
        1 tgaaattatt atgcattctg acaatattga agaggttaaa caaaactcag aaattgttgc
       61 gagatttttt cgtgaagggt ggaaaaaatt gcaaggattt taagggttag tttttgcata
      121 aatgataact aagttagcta ataatgttat tttatttgga ggtgttgatt atgaaacaaa
      181 aaagtcctgc tgctatattg tgggagcttg caaaaaagga acattcaaag ttaaaaacat
      241 ctgtatttat agcgagtatc ggtgttattg cagggattgt tccatatatt gcagcaagtc
      301 gtattttagt tgaattgtta aagggaaatg aggattttaa aatttattct ttatggttag
      361 gaataggatt gttatcctac atcttaaaat catttttata ctctatggct ttatctgtat
      421 cccataaagc aacttttagt gtactgaaag atgttcgttt aagaatgctt gaaaaacttc
      481 cgaagatgcc attaggagaa ataatctctg ttccaagcgg aaactttaag cagattatag
      541 tggatcaggt tgaaagtatg gagaaaccgc tcgctcacct gttgcctgaa atgacatcga
      601 atctcttagg ttctttgagt atatttattt acttattatt tcttgattgg agaatggctc
      661 ttttatcatt aatatccatt cctgtgggga tgctttttat gggactcgta atgaaaaatt
      721 atgctgttca atatgaagga tctgtaaagg taaatcgaga aatgaattct gcaattattg
      781 agtatgttaa tggaatagaa gtgataaaaa catttaatca agacaagaga tcgtacgcaa
      841 agtacaaaga taaagtcatt gcaaatgcaa gatactttta tgaatggatg aagagctgtc
      901 agttacctgt atctttatct aaaaacatat ctcctactac aatgatcaca gtgcttccat
      961 ttggttggta tttctacatt agcggcagtt taagtgcaga agtatttata tctgtaatta
     1021 ttctatcttt aggtattgca ggacctttac ttgaaacgat caattttgtt gatggtcttg
     1081 ctaagatagg gactattgca aattctatta acttaatttt agaaggaaaa gaacaaaagc
     1141 attctgatag agaagtgact atccagcaat ataatattga tttacaaaat gtaaagtttg
     1201 gatatgaaga agaaaaagaa attcttcatg gaatatccct aaacataaaa gaagggacaa
     1261 cagtggcttt tgttgggcca agtggaagtg gcaagtcaac tttagcaaaa ttaatagctg
     1321 gatattggga tattacggaa ggaaatataa atattggtgg atacaatctt aatgaaattc
     1381 cattaaagca attatatagt ttaactgcct ttgtttcgca ggataatttt ttgttcaacg
     1441 aaagtattag ggaaaatatc cgaatgggta atccaagtgc cagtgataaa gaagtagaag
     1501 acattgctaa gaaatcgggt tgtcatgatt ttattatgaa aatggaacat ggttacgata
     1561 cggttgtcgg aagtagtggt agccatgttt ctggtggaga aaggcaaaga atatctatag
     1621 caagagcaat gctcaaaaat gcacctattg taatacttga tgaagctact tcatatatag
     1681 atcctgaaaa tgaagtgatt ataaagcaag ctttatcaaa gcttataaaa gataaaacgg
     1741 tgattattat tgctcataga ttatcaacta taacagatgc agaacaaata ttcttaattg
     1801 agaatggaaa acttgtttca tacggtaagc atgatgaatt attaaaaggt tgtgaattat
     1861 accgaaatat gtggaacgct catataggaa caaaggatgg tgggatgaaa tgttaagtgc
     1921 tttaaaaaag attttagatt tctcaggtga tgaaaagaaa aatgtatatc actctatatg
     1981 ggtaagtttt ttgtttgcga tttttcatat gcttcaaatc agtgctattt attttatagt
     2041 gaaagcaatt gtccaaaaag acatgagcat gatgcccgcg tggatcgcat taatacttct
     2101 tgttattagc ataattggaa gaagtgttac aaattatttt tcacaattac agcaatgcca
     2161 tgcaagttat ttcatggtgg caaataaaag agtagcaata ggtgaaatgt taaaaaaaat
     2221 acctatggga tttttcaatg aaaacaatat tggtgaagtg gttggaattt ctacaactgt
     2281 tttagaagat gtagaaaata ccgcagcaat ggttatggta aatacattat caggttttat
     2341 aaacacgata atatttacaa taatgatttt agcatttgag tggagaatag gttttattgt
     2401 tgcaattgga tgcctattgt acttatttgt tctctcaaaa atggaaagca aatcaaggag
     2461 tgttcttcct aaaagacaaa aagcatctgc taaattagtt gatgccattt tagaacaaat
     2521 tggaggaatg tctgttataa aatccttcaa tttaacaggg aaaggagatg aaaaagtcag
     2581 aggtgctatt gaaaatagta gaaaaataaa tcttg
//
LOCUS       DARYSY010000112         2543 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYSY010000112 DARYSY010000000
VERSION     DARYSY010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2543
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..2356
                     /locus_tag="TVR04_001936"
     rRNA            <1..2356
                     /locus_tag="TVR04_001936"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2441..>2543
                     /gene="rrf"
                     /locus_tag="TVR04_001937"
     rRNA            2441..>2543
                     /gene="rrf"
                     /locus_tag="TVR04_001937"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          704 a          525 c          761 g          553 t
ORIGIN      
        1 aaaccgtgtg cctacaagaa gttcgagccc gttaatgggt gagagcgtgc cttttgtaga
       61 atgaaccggc gagttacgtt tacgtgcgag gttaagttga agagacggag ccgaagggaa
      121 accgagtctt aatagggcgc aagtacgtgg acgtagaccc gaaaccatgt gacctaccca
      181 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
      241 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
      301 ctccgaaata gctttagggc tagcgtcgat atgaagtctc ttggaggtag agcactgttt
      361 gggtgagggg tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgagatat
      421 gatcggcagt cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca
      481 ccagctaagg tccccaaata actgttaagt ggaaaaggat gtggggttgc acagacaact
      541 aggatgttag cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag
      601 tgaccctgcg ccgaaaatgt accggggcta aaacagttta ccgaagctgt ggattaccgt
      661 taaggtaatg gtaggagagc gttctatgtg tgatgaaggt atactgtgaa gagtgctgga
      721 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
      781 gtaagactaa ggattccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
      841 agaccgaagg gtgtatccga tggacaacag gttgatattc ctgtactaga gtatatagtg
      901 atggagggac gcagtaggct aactaaaccg gacgactgga agagtccggc taagcagtga
      961 ggtgtgatgt gagtcaaatg cttacatcta taacattgag ctgtgaaggg gagcgaagtt
     1021 aagtagcgaa gttagagacg tcacactgcc aagaaaagct tctagcgata cgtatactct
     1081 acccgtaccg caaaccgaca caggtagtcg aggcgagtag cctcaggtga tcgagagaac
     1141 tctcgttaag gaactcggca aaatggcccc gtaacttcgg gagaaggggc gctgactgca
     1201 agtcagccgc agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa
     1261 tcgtaagatg atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct
     1321 tagcgcaagc gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc
     1381 ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt
     1441 gggcactgtc tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc
     1501 cgcgacagga cggaaagacc ccatggagct ttactgcagt ttgatattga gtatctgtac
     1561 cacatgtaca ggataggtag gagccataga agtcgggacg ccagtttcga tggaggcgat
     1621 gttgggatac tacccttgtg ttatggctac tctaacccgg ataggtgatc cctatcggag
     1681 acagtgtctg acgggcagtt tgactggggc ggtcgcctcc taaaaagtaa cggaggcgcc
     1741 caaaggttcc ctcagattgg ttggaaatca atcgcagagt gtaaaggtat aagggagctt
     1801 gactgcgaga gcaacacctc gagcagggac gaaagtcggg cttagtgatc cggtggtacc
     1861 gtatggaagg gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc
     1921 cccaagagtt cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg
     1981 ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt
     2041 tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga
     2101 tctgctccta gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtctcgcc
     2161 agaggcatag ctgggtagct atgtagggaa gggataagcg ctgaaagcat ctaagtgcga
     2221 agccctcctc aagatgagat ttcccataac gttaagttag taagagccct gagagatgat
     2281 caggtagata ggttaggagt ggacgtgtgg tgacacatgg agcggactaa tactaatagc
     2341 tcgaggactt atccaaaaga tgaaaccagt cgctattgac agcttaagga attcttgtta
     2401 gactatagtt attcaatttt gagtggagaa gactcgtaag ttaagtgacg atagcctagg
     2461 agatacacct gtacccatgc cgaacacagt agttaagccc tagaacgcct gaagtagttg
     2521 ggggttgccc cctgtgagat acg
//
LOCUS       DARYSY010000113         2421 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYSY010000113 DARYSY010000000
VERSION     DARYSY010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2421
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            7..864
                     /locus_tag="TVR04_001938"
     CDS             7..864
                     /locus_tag="TVR04_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1270597.1"
                     /translation="MNKSIKRGVAIALLLFTFTVPKATFAMTNEGQIENQSESIYEPQ
                     KEEFEKMLKDDVFTPSKEEIPYQDVPRIPGNTSEANKPSNNPPKKTPLVKGGNTKAVN
                     NLATQENKARGSVIENVDRNGKDITPSGDTEKDKENPIDVRQFLTFQTKSGKTMHLIV
                     DHSSNQDNVRLLTEVGEQDLLNMIESEDKNTIKVEEPKKEEVKKEEPKTVPVKEEKKS
                     GIGSFLIVALVIGGVIGAGYYFKVVKAKEDKMLEDFEEDDEDYISESEDDDDDETHEE
                     SLDEDDELL"
     gene            938..1549
                     /locus_tag="TVR04_001939"
     CDS             938..1549
                     /locus_tag="TVR04_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270598.1"
                     /translation="MSSYTEKISDKINDFDSHKVFFANDFLDVTSYETARKTLNRMVN
                     ERKIKRVIDGFYYNPRYSELIGEYEAVSIHELALAIARKYNWNIAPYSSTALNLLGLS
                     TQVPTHYKYISSGRYKEYKIGDTILEFKKINPGEIANMSLKTATVIQAIKSLGKENIT
                     NEVIQKIRENLAEKERTDLMNESKSVPSWIYEVIREICEGKNE"
     gene            1542..>2421
                     /locus_tag="TVR04_001940"
     CDS             1542..>2421
                     /locus_tag="TVR04_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002834743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1270599.1"
                     /translation="MNKFYIEDKEDLRVLIVNTARKKNISEAVIEKDYWVTFILDYLF
                     NENKWKDYLTFKGGTSLSKCFGLIERFSEDIDLILDWRVLGYEEKEPWIERSNTKQDK
                     FNKAVNEKTEIFLRDEFLKVLEEDLKDMDFEFWVDSHDPQTILCKYPKIFESNYLTQN
                     IRLEIGSLAARTPAIDVEILPIIGEAYPNVFKEKTNIRTVSAERTFWEKATILHHEAN
                     RPESSSMPHRYARHFYDLYKIANSDFKNKALEDKDLLKKVTEFKMKFYPRKWARYEDA
                     LIGKLKLVPREYRFSEI"
BASE COUNT         1029 a          293 c          451 g          648 t
ORIGIN      
        1 agaaaaatga ataagagtat taaacgagga gtagccatag cgttactcct ttttacattt
       61 acagtaccaa aagctacatt tgcgatgaca aatgaaggac aaatagaaaa tcaaagtgaa
      121 tcaatatatg aaccgcaaaa agaagaattt gaaaaaatgt tgaaagatga tgtttttaca
      181 ccatcaaaag aagaaattcc ttatcaagat gttccaagaa taccaggaaa tacaagtgaa
      241 gcaaataagc cttcaaataa tcctcctaag aaaacacccc ttgtaaaagg tggtaataca
      301 aaggcagtaa ataatcttgc gacacaagaa aataaggcaa gaggttcagt aattgaaaat
      361 gtagatagga atggaaaaga tattacacca agtggagata cagaaaaaga taaagaaaat
      421 ccaattgatg taagacaatt tttgacattt caaaccaaaa gtggaaaaac tatgcaccta
      481 atagtagatc actcatcaaa tcaagataat gtaaggctat tgacagaagt aggagagcaa
      541 gacctactta atatgattga atcagaagat aaaaatacta taaaggttga agagcctaag
      601 aaagaagaag taaaaaaaga agaacctaag actgttccag taaaagaaga aaagaaaagc
      661 gggataggtt catttctaat tgttgcactt gtaattggag gagttatagg agcaggatac
      721 tattttaagg tagttaaagc aaaagaagat aaaatgttgg aagactttga agaagatgat
      781 gaggattata ttagtgagtc agaagatgat gacgatgatg aaactcacga agaatcttta
      841 gatgaagatg atgaactatt ataagaatat taaatttaag tacaattgaa cttttgtccc
      901 agatatgata tgatatttgg gacaaagggg gattgtaatg agttcatata cagaaaaaat
      961 atcagataaa ataaatgatt ttgactcaca taaagtattt tttgctaatg actttttaga
     1021 tgttacatct tatgaaactg ctagaaagac attgaataga atggttaatg aaagaaaaat
     1081 taagcgtgtc attgatggct tttattacaa tccaagatac agtgaattaa ttggagagta
     1141 cgaagcagta tcaattcacg agttagcact tgccatagca agaaaataca attggaatat
     1201 tgcaccatat agtagcacag ccttaaactt attaggactt tcaacacaag ttccaactca
     1261 ctataagtat atatctagtg gaagatacaa agaatataaa attggagata caattttaga
     1321 gtttaaaaaa ataaatcctg gagaaattgc caatatgtcc ctaaagactg caacagttat
     1381 tcaagcaatt aagtctttag ggaaagaaaa tataaccaac gaagttatac aaaagataag
     1441 agaaaactta gctgaaaaag aaagaacaga cttaatgaat gaatcaaaat cagtgccatc
     1501 atggatatat gaagtaataa gggaaatttg tgagggcaaa aatgaataag ttttatatag
     1561 aggacaaaga agacttaaga gttttaatag tcaatactgc aagaaagaaa aatatatctg
     1621 aagcagtcat tgaaaaagac tattgggtta cttttatctt agactatcta tttaatgaaa
     1681 ataaatggaa agattattta acctttaaag gtggcacatc actttcaaag tgttttggac
     1741 tgattgaaag attttctgaa gatatagatt taatcttaga ttggcgagta ttaggatatg
     1801 aagaaaaaga accatggata gaaaggtcaa ataccaagca agataaattc aacaaagcag
     1861 ttaatgaaaa gacagaaata tttttaagag atgaattttt aaaagtttta gaagaagatt
     1921 taaaggatat ggactttgaa ttttgggttg atagtcatga tccacaaaca attctgtgta
     1981 aatatcctaa aatttttgaa tctaattatt taacacaaaa tataaggctt gaaataggaa
     2041 gtcttgcagc aaggacacct gcaatcgatg ttgaaatatt accaataatt ggagaagcct
     2101 atccaaacgt atttaaagaa aaaaccaata taaggacagt atcggcagag agaacatttt
     2161 gggaaaaggc aacaatactt catcacgaag caaatagacc agaatcttct tctatgccac
     2221 ataggtatgc gagacacttt tatgacctat ataaaatagc aaattcagat tttaaaaaca
     2281 aagccttaga ggataaagat ttattaaaaa aagtgactga atttaaaatg aaattttatc
     2341 ctaggaagtg ggctaggtat gaagatgcat taattggcaa attgaagtta gttccaagag
     2401 agtaccgatt ttctgaaata g
//
LOCUS       DARYSY010000114         2351 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYSY010000114 DARYSY010000000
VERSION     DARYSY010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2351
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            526..1263
                     /locus_tag="TVR04_001941"
     CDS             526..1263
                     /locus_tag="TVR04_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1270600.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLL
                     ANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
                     IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            1633..1863
                     /locus_tag="TVR04_001942"
     CDS             1633..1863
                     /locus_tag="TVR04_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1270601.1"
                     /translation="MNTKTVEQFSTMTADMLASVEGGNCNWHGFTQAAVFSGAGNGFR
                     LGVKTRTWQGAAAGAAGGLVIGAVGYGAVCWW"
BASE COUNT          731 a          352 c          505 g          763 t
ORIGIN      
        1 caataattct agaaacttat tgcttggaga aggtatagct gcaagcagct aatcatcaga
       61 tagcctcagt gacctgacta gccattgtta gttttcctta tttaccattt aagacataat
      121 cagtaccatt taagatttta actccctgct ccctagcttt gtgttagaat gtctgtgcaa
      181 ggagatcagt gtgtggattg atagctgatg acttgtcaaa caaaagtgat agtcgttaag
      241 agctctctct caaagaggta tgacttgcgg ctcgtgctag tatattatct gtggtaaaaa
      301 aattatttga ggcgcgtgat tcgttaaggc ctattgaaaa cgctgcaatg acaagttggt
      361 tagaagtcat tgacaacctt tagttaataa gcttaacagt catggtttta atggtgatgc
      421 taaaaagata ctgttcatga aggagagcat tctagctatc acttgttcaa aaagctgctt
      481 tagtctccta aaaaacgata agctaaagca acaaggaggt tcaaaatgaa tatttttatt
      541 ctcgaagatg atctaggcca acagtttagg cttgagatga agattcaaga gatattggat
      601 aagcatcact ggacgtgtga tcgttttgaa gtttatggaa agccccatca gcttctggca
      661 aatgttacag agagaggcag gcatcagctt ttctttctcg atagtcaaat tcgaaatgat
      721 gagaaaaagg gcttagctgt tgctcgtgag attagaaagc gtgaccctta cgctctcatt
      781 gtttttgtca cgacacattc tgagcttatg ccagtttctt ttcgttatca ggtgtctgct
      841 ctagatttta tcgataagga attgtcaatg aaacatttct cagataggat tgaaagagcc
      901 attatatatg cttatgaaga gcaagaaaat gtaacctcag agggcttatt tatttttgta
      961 acggctaagg ctcaggtgca ggttcctttt tcaagcctat tgttcattga gacctctagt
     1021 actcctcaca agttgatttt gtattctcaa aacgagcgaa tagaatttta tggctttctt
     1081 tcagaggttc ttaagcaaga tcccagacta gtccaatgtc atcgttctta tgttatcaat
     1141 ccttacaatg tttcgtttct tgatcgtgat aagcgtttac tctatttcaa gaatgggcag
     1201 tcttgcatgg tttcaagact aaaaatgaaa gcacttgagg cgtctattaa ggctttgcat
     1261 tgacagtaaa aaatgctatg tgggagctat catttgcttt ttaacaacct cgttgatacc
     1321 ctttacctta agggctattc attataaaga tgtttagtca aaactaagaa aaaggggtaa
     1381 cagttggttt ctaatgatgc tcagagatat gatgttcatg caaaaagcaa ttatatcata
     1441 agaaaagaga aaaaaagata tagctcgtga aaggtatcta tatgatctta actggtaatt
     1501 tcagaagaaa aattgaccat tcacgacaaa taagaaccat tcaagacttt tgagtgtcgt
     1561 tgctttaaaa agtgctacac taagtttatc gagactgcag ctagataaga tcattataag
     1621 gaggtattcg atatgaatac aaaaacagtt gaacaattta gtacaatgac tgctgatatg
     1681 cttgcaagcg ttgaaggtgg gaactgtaat tggcatggct ttacacaagc agcggtgttt
     1741 tcaggagctg gaaatgggtt tagactaggt gtcaaaacaa gaacatggca aggggcagca
     1801 gcaggggctg ctggaggact agtgattgga gcagtgggtt acggcgctgt ttgctggtgg
     1861 tgagttcaat ggatttgaag tcatttatcc tagggttagt ggttggtttt ttgttaccct
     1921 attgtgatca aaaattgtta aacattttaa agaccttatt caaaaaataa tgctagtctg
     1981 aatgctgtca gatgattatt tagaatataa acagtagcta aatagcatag tactgtggat
     2041 aaacctagag tatataaggt ttgatggtta atcatctaga aagcaatgaa gtggtgttta
     2101 taataatgtc ataattaggt atcttggtgc ttttactctt tggtcttact agaaaggaga
     2161 aaaggctctg atcagaatgg taataatttt attgcttctg gttgtcagta gaaggatttt
     2221 gaatgttatt gttgattaat ttatattagc tggggctctg attggtagag ttattatgaa
     2281 tattattaca tggtctattg ttggtacaaa attagtaata gctattacat tttttcaaca
     2341 atatatgaaa a
//
LOCUS       DARYSY010000115         2350 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYSY010000115 DARYSY010000000
VERSION     DARYSY010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2350
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            13..2166
                     /locus_tag="TVR04_001943"
     CDS             13..2166
                     /locus_tag="TVR04_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1270602.1"
                     /translation="MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKT
                     TQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGLSYPFIAHVLKKGKFLHYYVVTG
                     QDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
                     LAKQKGLITNIVVATLLVTIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYAL
                     QQVISYAQEYLLLILGQRLSIDVILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSII
                     DALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAVIIFAFMKPFERMNQ
                     ETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQR
                     ALKKVAQLILNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVESEFSEKKNVQDLSLTSGDIKFNDVSYRYGYGKDVLSEINLHIK
                     RGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHINYLPQQ
                     PYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDSPILILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS"
     gene            2181..>2350
                     /locus_tag="TVR04_001944"
     CDS             2181..>2350
                     /locus_tag="TVR04_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComB"
                     /protein_id="HEL1270603.1"
                     /translation="MNNNILESAEFYNRRYHNFSSRVILPTLLLFLFGVFFLAFAKKE
                     ISIISTATVEPN"
BASE COUNT          731 a          395 c          449 g          775 t
ORIGIN      
        1 ttaggagatt ctatgaaatt tagaagaaaa cactaccgtg ctcaggttga tactcgcgat
       61 tgtggcgtag cttctctggc catgatttac ggttattatg gatcgtatta ttcgctagca
      121 acgttacgtg aagctgcaaa gacaacgcag gaagggacta cagcttttgg tttagtcaaa
      181 gtttctgagg cgcttgggtt tgaaacgaga gctattaggg ctgacatgag tttatttgat
      241 gtggaaggat tatcttatcc ttttattgcc catgttctaa aaaaaggtaa gttccttcat
      301 tattatgtgg taacaggaca agataaaaaa tatattcata ttgcagatcc agatccaact
      361 gtaaagttga cttgtctttc tcgtcagcga tttgcttcag agtggacagg tgtgacaatt
      421 tttatcgctc ctactcctga atacaaacct cacaaggaaa agaaaaatag tctgctagat
      481 tttgtgcctc tcctagcaaa gcaaaaagga ttgattacta atatcgttgt ggcaacgctt
      541 ttggtaacga ttatcaatat tattggttcg tattatcttc aatcaatcat tgatacctat
      601 gttcctagtg tgatgaagaa tacactaggt attatttccg taggtttggt tattgtctat
      661 gcccttcaac aagtgatctc atatgcgcaa gagtatttat tgctgatatt agggcaacgt
      721 ttatctattg atgtaattct ttcttatatc aaacatattt tcaaccttcc tatgtctttt
      781 ttcgcgacga gaaggaccgg ggaaattgtt tctcgtttta atgatgctaa ttcaatcatt
      841 gatgctttag caagtacaat tttatctatt ttccttgatg tttctgtcat tgtaattata
      901 tctcttgttc ttttttcgca gaatgtaaat ctatttgtta tcagtttgct tgctctgcct
      961 atctatgcag tgattatctt tgccttcatg aagccatttg aacggatgaa tcaagagaca
     1021 atggaagcaa attcaatcat gtcatcttct attattgaag atataaacgg tattgagact
     1081 attaaatcat taactagcga aaagataaga taccaaaaaa tagataaaga atttgtagct
     1141 tatcttaaga aatctttcaa ctatagtagg gcagaaagcc aacaacgagc attgaaaaaa
     1201 gtagctcagc ttatcctaaa cgtgagcata ctctggatag gagccaatct ggttatggac
     1261 ggaaaaatga gtttaggtca actgattacc tataactctc tcctaatcta ctttacaaat
     1321 cctctggaga atattatcaa tcttcaaacg aaacttcaaa ccgctcaagt cgctaataat
     1381 cgattgaatg aggtatatct agttgaatcc gagttctctg aaaagaagaa tgttcaagac
     1441 ttatctttga cctctggtga cataaaattc aatgatgtta gctatcgata tggatatgga
     1501 aaagatgttt tatcagaaat aaatttgcat attaaacgag gaagcaaggt tgcttttgtt
     1561 gggatttcag gttctggaaa aacgacttta gctaagatga ttgtcagttt ctttgaacca
     1621 agcaaaggcg aaatatcatt aaataatgtg aatctaaatc aaattgacaa acatgctctt
     1681 cgccagcaca ttaactatct tcctcaacaa ccttacgtat ttaatgggac aatccttgag
     1741 aatttacttc ttggagcacg tgaagggacg actcaagaag acattatgaa ggcagtagaa
     1801 ttggctgaaa tcaagtctga tattgaacgt atgcctttga attatcaaac agagttaacc
     1861 tcagatggtg cagggatttc tggaggtcaa cgtcaacgta ttgccttagc aagggcatta
     1921 ttgacagatt ctcctatttt gatattagac gaagctacaa gtaacttgga tattttgact
     1981 gagaagcgaa ttgttgataa cctgatggct ttagataaaa ccttgatatt tattgctcac
     2041 cgtttaacta ttgcagagcg tacagagcat gtcgtcgttt tggataaagg aaagatcata
     2101 gagcaaggaa cacacagaga ccttgtttct cagaatggct tttatgctca cttggtcaat
     2161 agttaggagg gtttgataaa atgaataaca atatattaga aagtgcggaa ttttataacc
     2221 gtcgttacca caacttttct agtcgtgtca ttctacctac tttgctgctt ttcttgtttg
     2281 gtgttttctt cctagcattt gcaaagaaag aaatttctat tatttcaact gcaacagttg
     2341 aaccaaatat
//
LOCUS       DARYSY010000116         2164 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYSY010000116 DARYSY010000000
VERSION     DARYSY010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2164
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..303
                     /locus_tag="TVR04_001945"
     CDS             <1..303
                     /locus_tag="TVR04_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper amine oxidase"
                     /protein_id="HEL1270604.1"
                     /translation="GFNVEYDNSTREAIFSNKENNILAKKTLRLNIDTGVMKDSDGKV
                     YNSDVKPVIINGRIHASISNIAKAFGASHGDIKDGKNQTIEWDNARKAVYVFKNVK"
     gene            318..1196
                     /locus_tag="TVR04_001946"
     CDS             318..1196
                     /locus_tag="TVR04_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1270605.1"
                     /translation="MNKSIKRGVAIALLLFTFTVPATTFAMTNEGQIESQNESIYEPQ
                     KEEFEKMLKDDVFTPSKQEIPYQDVPRIPGNTSEATKPSTNPPKKTPLVKGGNTKAVN
                     NLATQENKARGSVIENVDRNGKDITPSGDTEKDKENPVDVRQFLTFQTKSGKTMHLIV
                     DHSSNQDNVRLLTEVGEQDLLNMIESEDKNTIKVEEPKKEEVKKEEPVEEKPKKEEKE
                     EKKSGIGLYLFMGLIIVGVMGAGYYFKIYKKNEEASFEDEQDYNELEDDYESEGEDYN
                     LEDKEDTEVIPDEDEF"
     gene            1259..>2164
                     /locus_tag="TVR04_001947"
     CDS             1259..>2164
                     /locus_tag="TVR04_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1270606.1"
                     /translation="MKLVIAEKPSVAASIAKVIGAKNRNNGYYEGNGYIVSWCVGHLV
                     QMANPDVYDERYKKWRIEDLPIIPKEYKYEVTKTTKKQFNILKRLMNSNEVDTIINAC
                     DAGREGEAIFRLVYMMANCKKKMKRLWISSMEDSSIKEGFSNLKDGSNYDNLFDSAKA
                     RAIADWLVGMNMSRLYSCLYNENYSVGRVQTPTLSMIVNRDDEINSFKKEKYYTVEIS
                     MNGFTLSTDRIDDKIVAEQLKNLIGEKIEITDVIKKEKITKPNLPFDLTTLQRECNKY
                     FGYSAKQTLDYAQSLYEKKYITYPRT"
BASE COUNT          911 a          266 c          429 g          558 t
ORIGIN      
        1 ggttttaatg ttgagtatga caactctact cgtgaagcta ttttctcaaa taaagagaat
       61 aatatcctgg ctaaaaagac attaagacta aatattgata ctggtgtcat gaaagattca
      121 gatggaaaag tctacaattc agatgttaag cctgtgataa taaatggaag aattcatgct
      181 tcaatttcaa atattgctaa agcttttgga gcaagtcatg gagatattaa agatggtaaa
      241 aaccaaacaa tagaatggga caatgctaga aaagcagtct atgtatttaa aaatgtaaaa
      301 taagaaagga tagaaaaatg aataagagta ttaaacgagg agtagccata gcgttactcc
      361 tttttacatt tacagtacca gcaactacat ttgcaatgac aaatgaagga cagatagaaa
      421 gtcaaaacga atcaatctat gaaccacaaa aagaagaatt tgaaaaaatg ttgaaagatg
      481 atgtttttac accatcaaaa caagaaattc cttatcaaga tgttccaaga ataccaggaa
      541 atacaagtga agcaaccaag ccttcaacta atccgcctaa gaaaacacca cttgtaaaag
      601 gtggtaatac aaaggcagta aataatcttg cgacacaaga aaataaggca agaggttcag
      661 taattgaaaa tgtcgatagg aatggaaaag atattacacc tagtggagat acagaaaaag
      721 ataaagaaaa tccagtagat gtaagacaat ttttaacatt tcaaaccaaa agtggaaaaa
      781 ctatgcacct aatagtggac cactcatcaa atcaagataa tgtaagatta ttaacagagg
      841 taggagagca agacctactt aacatgattg aatcagaaga taaaaatact ataaaggttg
      901 aagagcctaa gaaagaagaa gtaaaaaaag aagaaccggt ggaggaaaaa ccgaagaaag
      961 aggagaagga agaaaagaaa tcagggatag gactctattt atttatgggt ttaattattg
     1021 ttggtgtaat gggtgcagga tattacttca aaatctataa gaaaaatgaa gaggcaagtt
     1081 ttgaagatga gcaagattat aatgaattag aagatgatta tgaatctgaa ggggaggatt
     1141 ataatcttga agataaggaa gatacagaag ttattccaga tgaagatgaa ttttaatctt
     1201 ttcaatgatt taagcagtag attaaggaca acattattaa aaaactaaag gaggaaaaat
     1261 gaaattagta atcgcagaaa aaccaagtgt tgcagcatca atagcaaaag ttataggagc
     1321 aaaaaataga aataatggat attatgaggg gaatggatat attgtttcat ggtgtgttgg
     1381 acatttagta caaatggcaa atcctgatgt gtatgatgaa agatataaga agtggagaat
     1441 tgaagattta cctattatcc caaaagaata caagtatgag gtaacgaaga caactaaaaa
     1501 acagtttaat attcttaaaa ggctaatgaa tagtaatgaa gttgacacca ttattaatgc
     1561 ttgtgatgct ggtagagaag gggaagctat ctttagactt gtatatatga tggcaaattg
     1621 taagaagaaa atgaaacgtc tttggatttc ctcaatggaa gactcttcca taaaagaagg
     1681 atttagcaac ttaaaagatg gaagtaacta tgataatctt tttgattcag ctaaggctcg
     1741 tgccatagct gattggcttg ttggaatgaa catgagtaga ctttactcct gtctatataa
     1801 tgaaaattat agtgtaggca gagtacaaac accaacttta tcaatgattg tgaatagaga
     1861 tgatgagata aatagtttta aaaaagaaaa atattataca gtggagattt ccatgaatgg
     1921 atttacactg tcgacagata gaattgatga caagatagtg gcagagcagc ttaaaaattt
     1981 aatcggagaa aaaattgaaa taaccgatgt aattaaaaaa gaaaagatta caaagcctaa
     2041 tctgcccttt gacctaacaa cacttcaaag agaatgtaat aagtattttg gatacagtgc
     2101 aaaacaaacc ctagattatg cccaaagcct gtatgaaaag aagtatatta cctatccacg
     2161 aaca
//
LOCUS       DARYSY010000117         2105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYSY010000117 DARYSY010000000
VERSION     DARYSY010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            34..309
                     /locus_tag="TVR04_001948"
     CDS             34..309
                     /locus_tag="TVR04_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1270607.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGIFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            306..1628
                     /locus_tag="TVR04_001949"
     CDS             306..1628
                     /locus_tag="TVR04_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1270608.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKNKEISAANSAVLAN
                     KLLQMANGAIYDDDKVTVAIHDDKLDALENIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1629..1796
                     /locus_tag="TVR04_001950"
     CDS             1629..1796
                     /locus_tag="TVR04_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270609.1"
                     /translation="MKKEYVVRIYTDREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREWQK"
     gene            1793..2059
                     /locus_tag="TVR04_001951"
     CDS             1793..2059
                     /locus_tag="TVR04_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270610.1"
                     /translation="MTEELIKPLLEEIERKDDRLYKQANVIAVLMTAVIMLLMISIAL
                     QNHYEPQITGLRAQLSRTQKQLKRASEYRARQTKRIAELTGNGG"
BASE COUNT          732 a          348 c          494 g          531 t
ORIGIN      
        1 taaccctgac ctatattgac caaaggagga aagatgagaa ccgaaaaaga tattgaaaat
       61 tatttgaaaa agaaaacaaa agggctgtgt ttaaaattta ctagtccagg gacgatagga
      121 gtgcctgaca gaattgttgt catgaatacg ggaatctttt ttgtagaggt caaagcgcct
      181 ggtaaaaaac caagacccag ccaagttgca atgcacaaaa aaataaaaga ggctgggcag
      241 cacgtttggg ttgttgactc ctacgaatca gtggacatag ccttaaaaga aatggagaac
      301 tgggtgtgag actgcacgag taccaagaat acgctaagac atggatagta gagcaccctt
      361 attgtggcct tttacttgac atgggccttg gtaaaacgtt gacaacacta tcggcgatag
      421 atgagattca aaatattttt tccgaggatc ataagatttt aatcgtagcc cctaaaaaag
      481 tggcggaaga aacgtggcca acggagattg agaaatggca ttttgatttc acctactcta
      541 aagttttggg gagtgaggga aaacgaattg aagccttaga aacagaagcc gatatttatt
      601 tgattaatcg tgagaatgtt acttggcttg ttgaatacta caagactaaa tggccgttta
      661 cctttgttgt tattgatgag ctttcaagct ttaagtctag taagtcaaaa cggtttaggg
      721 ctttgcgaaa agttagaccg aaagttcaac gccttgtagg actaacagga accccagcgc
      781 ctaacagttt gattgatttg tggccgcaga tttatctgat ggacagaggc gacagacttg
      841 agacgagcca gactcgattt aaagacaagt attttgttcc tgataagcgt aatggtccaa
      901 tcatttacag ttgggcactt agggatggtg cagaagcaga aatctataac aagattgagg
      961 acatctgtgt cagcatgaaa gctaaagact atctcaagtt accgccgcga accgacaacg
     1021 ttgtatcagt taagttatct aatatgaaag cctacaaaca gcttgaagct gatttggtgt
     1081 tggagtttaa aaataaagaa atatctgcgg ctaattctgc ggttttggcc aataaattac
     1141 ttcaaatggc caatggtgct atctatgatg atgataaagt aacagttgct atacacgacg
     1201 acaaacttga cgcgcttgag aacatagtag aagaaagcca aggccagcca atcttagttt
     1261 tttaccagta tcaacatgat cttgagagac ttaagaaacg atttcctcag gctgaagagc
     1321 tgacgtcggt tgacaagtgg aattccggaa aaataccaat tcttctgtgc caccctcaat
     1381 cagctgggca cgggcttaat ctgcaaaaag gcgggcatat tattgtttgg tttgggctaa
     1441 cgtggagtct tgaatattat cagcaagcta atgccagatt agatagacag gggcagacag
     1501 aaccggttat tgtgcaccac attgttgcag aaaatacagt tgatgaaaaa gtacttagga
     1561 ttttacaagg caaagaaaaa aatcagaacg ccttacttga agcagttaag gcgcagttag
     1621 gagtctagat gaaaaaagaa tatgtcgtta gaatctacac ggatagagaa aagaattttg
     1681 aggcaaaacc tcagtttgaa gagaaaacct ttacgcgaaa agcagacatg ttgaagtttt
     1741 ggaattcttg cgaagcaaca gttaaagaaa aatatactag ggagtggcaa aaatgacaga
     1801 agaactaata aaaccgttgc tagaagagat agagcgaaaa gatgacaggc tgtataaaca
     1861 ggctaatgta attgccgtct taatgacagc agttattatg ttactgatga taagtatagc
     1921 cttacaaaac cactacgaac cgcaaataac aggactacgt gctcagctaa gcaggacaca
     1981 aaagcagctt aaacgtgcta gtgagtatag agctagacag acaaaacgga tagcagaatt
     2041 gacagggaat gggggataag gatggattat ttaatgattg gaattatagt attatcagta
     2101 gtaat
//
LOCUS       DARYSY010000118         2059 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYSY010000118 DARYSY010000000
VERSION     DARYSY010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2059
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1140
                     /locus_tag="TVR04_001952"
     rRNA            <1..1140
                     /locus_tag="TVR04_001952"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1194..1266
                     /locus_tag="TVR04_001953"
     tRNA            1194..1266
                     /locus_tag="TVR04_001953"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1227..1229,aa:Ala,seq:tgc)
     gene            1559..>2059
                     /locus_tag="TVR04_001954"
     rRNA            1559..>2059
                     /locus_tag="TVR04_001954"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          588 a          415 c          585 g          471 t
ORIGIN      
        1 gtgagtgaag aaggttttcg gatcgtaaag ctctgttgtt agagaagaac agtgatggga
       61 gtggaaagtc catcatgtga cggtaactaa ccagaaaggg acggctaact acgtgccagc
      121 agccgcggta atacgtaggt cccgagcgtt gtccggattt attgggcgta aagcgagcgc
      181 aggcggtttg ataagtctga agttaaaggc agtggcttaa ccattgtatg ctttggaaac
      241 tgttaaactt gagtgcagaa ggggagagtg gaattccatg tgtagcggtg aaatgcgtag
      301 atatatggag gaacaccggt ggcgaaagcg gctctctggt ctgtaactga cgctgaggct
      361 cgaaagcgtg gggagcaaac aggattagat accctggtag tccacgccgt aaacgctgag
      421 tgctaggtgt taggcccttt ccggggctta gtgccgtagc taacgcatta agcactccgc
      481 ctggggagta cgaccgcaag gttgaaactc aaaggaattg acgggggccc gcacaagcgg
      541 tggagcatgt ggtttaattc gaagcaacgc gaagaacctt accaggtctt gacatcccga
      601 tgctattctt agagataaga agttacttcg gtacattgga gacaggtggt gcatggttgt
      661 cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt
      721 agttgccatc attaagttgg gcactctagc gagactgccg gtaataaacc ggaggaaggt
      781 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgtg ctacaatggt
      841 tggtacaacg agtcgcaagc cggtgacggc aagctaatct ctgaaagcca atctcagttc
      901 ggattgtagg ctgcaactcg cctacatgaa gtcggaatcg ctagtaatcg cggatcagca
      961 cgccgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca cgagagtttg
     1021 taacacccga agtcggtgag gtaaccgtta aggagccagc cgcctaaggt gggatagatg
     1081 attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt
     1141 ctaaggaaaa aggaagcacg tttagcgtct tatttagttt tgagaggtct tgtggggcct
     1201 tagctcagct gggagagcgc ctgctttgca cgcaggaggt cagcggttcg atcccgctag
     1261 gctccattaa aacaggatac taacagacgg ttcggtttac cgaaaacttc tgtagaaaaa
     1321 taggaaatcg acgctgtgtg tttagcacac aaggagattt atcttttttc ctaagaagtt
     1381 agtctggtgt tcaactttgt agatcttgtt ttaattgata ttagcataca actttaatat
     1441 caaaaccttg tccattgaaa attgaataac tatatcatat tccgcaatca caaaagattg
     1501 taagaaagta acaagaaata aaccgaaacg ctgtgataac gagtttaaga aaaaataagg
     1561 ttaagttaat aagggcgcac ggtggatgcc ttggcactag aagccgaaga aggacgtgac
     1621 aaacgacgaa atgctttggg gagctgtaag taagcaaaga tccagagatg tccgaatggg
     1681 ggaacccact agctaatggc tagtatccat aactgttaag gttatgagaa ggaagacgca
     1741 gtgaactgaa acatctaagt agctgcagga agagaaagca aacgcgattg cctgagtagc
     1801 ggcgagcgaa aaggcaggag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     1861 gctgtgggac gacaagatta tagaagaagg ccttgggaag ggtcgccaaa gagagtaata
     1921 gcctcgtatt cgaaatagtc tttaacccta gcagtatcct gagtacggcg agacacgagg
     1981 aatctcgtcg gaatctggga ggaccatctc ccaaccctaa atactcacta gtgaccgata
     2041 gtgaaccagt accgtgagg
//
LOCUS       DARYSY010000119         2052 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYSY010000119 DARYSY010000000
VERSION     DARYSY010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2052
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            1..1822
                     /locus_tag="TVR04_001955"
                     /pseudo
     CDS             1..1822
                     /locus_tag="TVR04_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035800.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
BASE COUNT          756 a          226 c          413 g          657 t
ORIGIN      
        1 taatagtgtt aaaagaatgg ttgcagattt tactaatctt ctattagttg agtgtgaaag
       61 aaagaatgaa aaatttttag atagagtgaa aactatatct ggcacatttt tagaaaatgc
      121 ctctcacagc tcatactctg gagtgcaggt acaaagagat gtttataaag aagttggaaa
      181 aactatcaat attgcacctg tggtgtttgc ttgtaatata gattatcctt tagagactca
      241 ggaaacaaga aaaatattcg ggaaaataaa ctatatggta tcacaaactc cacaagtttg
      301 gctcgatttt caaacttatt tagtagatga tgagattgta ttatgctggg atgtggttga
      361 tgaattatat ccagatggaa tgattgatga tatgttcgac tctttataca ctttattaca
      421 atcattaagt gataatgaaa attggtatag attgcctgaa attcttccgt tgaatcagat
      481 tgaagataga gaaaaagaat taaaaaatat tttgcctttg agttacccta aacaaactct
      541 ctatacagaa tttcttgata ggattaaagt aaacccggaa aaagttgcta ttgtggatgc
      601 acaatccggt attgaattaa cttatggaga tttatacaaa aaggcgttaa ttattgcaac
      661 aaatttaatt tcttttggag taaaaaagaa tgactacgtg ggaataacat tgccaagggg
      721 atatagtcaa atagttggta ttttaggaat tttatttgcc ggcgcagcat atgttcctat
      781 cggtattaat caacccaacg aaagaagaag gaaaatatat gaacagatag gaataaaaca
      841 tgtcttatcc aataaaaata caataaggga ttttaattta gatgatacag atatcacatt
      901 tgttgatatg gatcaatcaa ctattcaaag tataattgaa aaacctgtca atattagtcc
      961 gtttgataca gcctatgtaa ttatgacatc aggaacgacg ggaattccta aaggtgtgga
     1021 aattgcacac aatagtgctg ttaatacaat caatgactta aatgaaagat atgaagtaaa
     1081 tgccaatgat agcgtaataa tggtatcagc aattgatttt gatttatcag tttatgatat
     1141 ttttggaata ttatcggctg gaggaactat cattacttta gatgataata atttcaaaga
     1201 tccggaactt tggttaaaac ttattgaaaa atatgaagta acaatgtgga attcggtgcc
     1261 aattcttttt gatatgctag taactatggc agagggtaaa gatgtttcta ttccattgag
     1321 attagttttt ctttctggag actggattgc aacaacatta cctaaaagat tttataacag
     1381 aagcaaaaat tctcttgtag ttggaatggg aggaggaaca gaggcttcca tttggtcaaa
     1441 ttatatcaat gttccaaagg aaatacctaa aaattggatt tctattccat atggaaaagc
     1501 gttaaagaac caagtctata gagtagttga tggtttagga agaatatgtc ctaactatgt
     1561 taaaggagaa ttgttaattg gtggggttgg tgttgcaaag ggatataggg gagataagga
     1621 attaacagaa aagaaattta tagaatcgga tggagttaaa tggtatagaa ctggagatgc
     1681 tggaagaaca tggaatgatg gaactattga atttttagga aggcttgata atcaggtaaa
     1741 agttaaaggg catcgaatag aacttggaga aattgaagat gctttaattg gaaatcctaa
     1801 aattaataaa gctgttgttg atgttattaa gattggcact aataatcaat tggtcgcatt
     1861 tattgaaagt aatgagagta aggattatac attaactaga ttaagtagta atgaaaaaat
     1921 aaataaactg aaatctgaat acattgatta tgatgagtat ctaaatagtg aaaataatat
     1981 ggttttaggt ttgatatttt ctattttcat ggatttgggt attagtcaag gaaaaaggta
     2041 ttcttttgat ga
//
LOCUS       DARYSY010000120         2003 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYSY010000120 DARYSY010000000
VERSION     DARYSY010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1292
                     /locus_tag="TVR04_001956"
     CDS             <1..1292
                     /locus_tag="TVR04_001956"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012711.1,HMM:NF024591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1270611.1"
                     /translation="ILMGHRYSEVKGILNKTNAKAYIGINRYLGFSYEDMVSNIIEDT
                     KEDLQVYLIGETEKYEKLCTLRQNRKNKFVEELEYKETAIFLLSGGTTGFPKLIPNRH
                     CEFIYLAKELANATDMNEDTVYLAALPMSHKFALCCPGMIGTLSKGGKVVTCRVSSPD
                     EIIPLIEEQEVSIMALVPTLANMCIEYLKNDDADISSLKYIQIGGSVLDSNLAKKIQE
                     EFNCKLLQLYGMSESLITCSRVLDDDYDRLHTQGKKLSEFDEARIVDEDGKEVPDGDF
                     GELIVRGPYTILEYYDSSKLNDTQFTEECFLRTGDRAAKLYGDNYKIVGRVLEMINRA
                     GEKIVPSELENILLTNKNIREVQIVGIPDETLGEKIGVFILKGSTVLTHRDIRNYLVE
                     RGLASFKLPDEVQYVDQWPLTSVGKVDKSKLKQQMIK"
     gene            1309..>2003
                     /locus_tag="TVR04_001957"
     CDS             1309..>2003
                     /locus_tag="TVR04_001957"
                     /inference="COORDINATES: protein motif:HMM:NF012759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1270612.1"
                     /translation="METYQTRQQAVRLLDEVLQANLDGFKPSGKDNLIEKGLGSIQIM
                     QIVSELKKLGIKLSFAKLMENPTLEDWIRLIEKANIKNIDKKTESREKNISEEFPLTD
                     VQYAYFVGREEDQVLGGVGCHAYLEIDGQEIVTDKLTAAWNCLQMENPMLRAKFNRNG
                     TQQIMEEPYSKEVKIFNYTSLSEEDADIKLLEMRKEMSHRKFDIEVGEVASLSIALLK
                     DKKHRIFLDIDILV"
BASE COUNT          752 a          225 c          426 g          600 t
ORIGIN      
        1 ttatcttgat gggtcataga tattcagaag ttaagggaat tttaaataaa acaaatgcaa
       61 aagcatatat tggaattaac aggtacttag gattttcata tgaagatatg gtgtctaata
      121 ttatagaaga tacgaaagaa gatttacaag tttatttgat tggcgaaaca gagaaatatg
      181 agaagttatg taccttaaga caaaatagaa aaaataaatt tgttgaagaa ttagagtata
      241 aggaaacagc tatattttta ttgtcaggag gtacaaccgg ctttccgaaa ctaataccta
      301 ataggcattg tgaatttata tatttagcaa aagaactggc aaatgcaaca gatatgaatg
      361 aagatacagt gtatttagca gctttaccta tgagccataa atttgcactt tgttgtccgg
      421 gaatgattgg gacattgtca aaaggtggta aggtagttac ttgtagagta tccagtcctg
      481 atgaaataat acctttgatt gaggaacagg aagttagcat tatggcattg gtacctactt
      541 tagctaatat gtgtatagaa tatcttaaaa atgatgatgc tgatatcagc agtttgaagt
      601 atatacagat aggtggatct gttcttgatt ctaacttagc aaaaaagatt caggaagaat
      661 ttaattgtaa attattgcaa ttgtatggca tgagtgagtc gttgattact tgctctaggg
      721 ttttggacga tgattatgac agattacata ctcaagggaa gaagttaagt gagtttgacg
      781 aagctcgtat tgttgatgaa gacgggaaag aggttcctga tggagatttt ggagagctaa
      841 tagttagggg accatatact attttggaat attatgattc atcaaaacta aatgatactc
      901 agtttacaga agaatgtttt ttaagaacag gagatagagc cgctaagtta tatggagaca
      961 attataaaat tgttggtcgt gtgttggaga tgataaatcg tgctggagaa aaaatagttc
     1021 cttctgagtt ggaaaatatt ttgcttacaa ataagaatat tagagaagtg caaattgttg
     1081 gcatacccga tgagactctc ggagaaaaaa taggtgtatt tattttgaag gggagtaccg
     1141 ttcttacaca tagagatata aggaattatt tggtagaaag aggacttgct tcttttaagt
     1201 taccggatga agtacagtat gttgatcaat ggccattaac aagcgttgga aaggtagata
     1261 aaagtaaatt aaaacaacaa atgattaaat agataaggag gctacaatat ggaaacatat
     1321 caaactagac aacaggcagt acgacttctt gatgaagtgt tacaagcaaa cttagatgga
     1381 tttaaacctt caggaaaaga caatttgatt gaaaagggtt taggctctat ccaaatcatg
     1441 caaatagttt cagagcttaa aaaattaggg ataaaattat cgtttgcaaa actaatggaa
     1501 aatcctacac ttgaagattg gattagactt attgaaaaag caaatattaa aaatattgat
     1561 aaaaagactg aatcaagaga aaagaatatt tcggaagagt tccctttaac ggatgtacag
     1621 tatgcttatt ttgtagggag agaagaagat caggttctag gtggtgttgg gtgtcacgca
     1681 tacttagaaa ttgatggaca agagattgta acagataaat taactgctgc ttggaactgt
     1741 ttacaaatgg aaaatccaat gcttagagca aaatttaacc gtaatggtac tcagcaaatt
     1801 atggaagaac catactcaaa agaagttaaa atttttaatt atacttcact atctgaagaa
     1861 gatgcagaca taaaattatt ggaaatgaga aaagaaatgt ctcatagaaa atttgatata
     1921 gaagttggag aagtagctag ccttagcatt gcgttactaa aggataaaaa acatagaata
     1981 tttttagata ttgatattct agt
//
LOCUS       DARYSY010000121         1885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYSY010000121 DARYSY010000000
VERSION     DARYSY010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1885
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..841
                     /locus_tag="TVR04_001958"
     CDS             <1..841
                     /locus_tag="TVR04_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1270613.1"
                     /translation="DYKAEGQIGREESPEEYLNKLIEVFREVKRVLKKEGTLWVVIGD
                     SYAGTRSKREYKDPKNIEGRSGQKEYITEKLSGYKAKDLMGIPWQLALKLREEGWYLR
                     SDIIWHKENAMPESCRDRPSRSYEHIFLLSKARKYFYDFDAMKEPIKEISKNRYMRAR
                     GKNNKYLQEGTGAKRQSINEAREYGEYIGDNVPKFRNNRDIWTINTSAFKGKHYAVFP
                     PKLVELCIKAGCPKKGLILDPFMGSGTVGMVAIRMDREYIGIDINKDYCQIAKERIEK
                     NMK"
     gene            851..>1885
                     /locus_tag="TVR04_001959"
     CDS             851..>1885
                     /locus_tag="TVR04_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004838434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270614.1"
                     /translation="MKKKGKVNPRDVPKTKLISEKKEESNEKFSNIEIPSDFSKKEIN
                     KVKSRNNIDNNVENSKYYSDHLQENSQDLFKEKEKPNRERRQRKIHEEKFAEASYHNE
                     YQPEYSQRQHRKMEENEESRYGEYHGQEREYRLSNFKEDFNDGVISTNSNIKSSISPQ
                     KNCNGNSNLKWKKNVESESFNDVPEEKIRRFRKEDKNFNREISSTYDPLSQDSDNDGV
                     IDRYDINFSDSNVSYRDTRDDYKYLPSSDVQRKNWDGYFILGEKGKESFQKNTFKKLY
                     QSQSQFKDKGEKAELKSLNGKFRRKDLSYKANEEDKKIIQDLNTNKKQNSKYFKGKVR
                     NLEEKNMLMGR"
BASE COUNT          846 a          208 c          385 g          446 t
ORIGIN      
        1 agattataaa gcagaaggac aaattggaag agaagaaagt ccggaggaat atttaaataa
       61 attaattgaa gtctttagag aagtaaaaag agtattaaaa aaagaaggaa cactttgggt
      121 agttattgga gattcttatg cagggacaag aagcaaaaga gaatataaag atcctaaaaa
      181 catagaagga agaagtggtc aaaaagagta tattacagaa aaactcagtg gctacaaggc
      241 aaaagactta atggggatac cttggcaact agctttaaaa ttaagagagg aaggttggta
      301 tttacgaagc gatattattt ggcataagga aaatgccatg cctgagtctt gtagagatag
      361 accatcaagg tcctatgaac atatctttct actatcaaaa gcaagaaagt atttctatga
      421 ctttgacgct atgaaagaac caataaaaga aataagcaag aacagatata tgagggcaag
      481 aggaaagaat aataagtatt tacaagaagg tacaggagct aaaagacaga gcataaatga
      541 agcaagagag tatggagaat atataggaga taatgtccct aagtttagaa acaatagaga
      601 tatttggact attaacacca gtgcatttaa aggaaaacac tatgcggtat ttccaccaaa
      661 actggtagaa ctttgtataa aagcaggatg tcctaaaaaa ggcttaattc ttgatccctt
      721 tatgggttca ggaactgttg gaatggtagc tattaggatg gacagagaat atattggaat
      781 tgacataaac aaagactact gtcaaatagc taaagaaagg atagagaaaa atatgaaata
      841 ggaggtatgt atgaaaaaga aagggaaagt aaacccaaga gatgtaccaa agaccaagct
      901 tatatcagaa aagaaagaag aaagcaatga aaaattcagt aatatagaga taccatcaga
      961 tttttcaaaa aaagaaataa ataaagtaaa aagcaggaac aacatagaca ataatgttga
     1021 aaactctaaa tattactcag atcatttgca agaaaatagt caggatttat tcaaagaaaa
     1081 agaaaagcca aatagagaaa gaagacaaag aaaaatccat gaggaaaaat ttgcagaagc
     1141 ctcctatcat aatgaatatc agccggaata ttcgcaacgg cagcatagaa aaatggaaga
     1201 aaatgaggaa agtagatatg gtgaatatca cgggcaagaa agagaatata ggctaagtaa
     1261 ttttaaagaa gattttaatg atggagtaat ttcaactaac tctaatataa aaagtagcat
     1321 ttctcctcaa aaaaattgca atgggaatag taatttaaaa tggaagaaaa acgttgagag
     1381 tgaaagtttt aatgatgtgc cagaggaaaa aataaggaga tttagaaaag aagataagaa
     1441 ttttaataga gagataagtt caacatatga tccattatca caggactcag ataatgatgg
     1501 tgtcatagat cgctatgaca ttaactttag tgatagcaat gtatcctata gggatacaag
     1561 ggatgactat aagtatttac catcttctga tgtgcaaaga aaaaattggg atggttattt
     1621 tattcttggt gagaaaggga aagaaagctt tcaaaaaaac acctttaaaa aactttatca
     1681 atctcaaagt cagtttaagg ataaagggga aaaagcagaa ttaaaatctt taaatgggaa
     1741 gtttagaaga aaagatctat catataaggc aaatgaagaa gataaaaaaa taattcaaga
     1801 cctgaatact aataaaaaac aaaatagcaa atatttcaaa ggcaaagtta gaaatttaga
     1861 agaaaaaaat atgctaatgg gtagg
//
LOCUS       DARYSY010000122         1869 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYSY010000122 DARYSY010000000
VERSION     DARYSY010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1869
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            75..1796
                     /locus_tag="TVR04_001960"
     CDS             75..1796
                     /locus_tag="TVR04_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1270615.1"
                     /translation="MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGNGYIVSWCVGHLI
                     QMASPERHDEKWKKWTIDTLPIIPEDYIYEVSKSTKKQYGVLKKLLNDKNIDTVINAC
                     DAGREGELIFRLVYNQAKCKKKIQRLWISSMENKAIEDGFRNLKDGENFEDLYRSASA
                     RAIADWLVGMNLSRLYSCIYKETYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLS
                     YGGLKLVSDRIDRIEVAEQLLNLLEDEIVITEVEDKEVSTKPDKPYDLTTLQREANKY
                     FGYSANDTLNLAQALYEKKLITYPRTDSRYLTDDMVTTMKELLEGLEDDFKINESNFK
                     SIFNSSNVTDHYAIIPTISGIGKAKDLSDRESKIYNLIKNKLLASCSDNLKESSRKIR
                     YEYDKFNFNASGKTIIDEGYTKYLKTYGKEKQENELPDVKTGDKIKLTSKKISEKFTK
                     APSHYNEDTLLKAMENAGVESLDKDIEVERKGLGTPATRAGIIENLIHKDLIRRDKKN
                     LLVSEKGNRLVSIVEDKFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIRELVDR
                     YKNNLNE"
BASE COUNT          766 a          225 c          364 g          514 t
ORIGIN      
        1 aaatacaata ttcgggagaa atactttgag cgagagagaa atctttcgct ctttttttat
       61 ttatggaggt attaatgaag ttagtaatag cagaaaagcc aagcgtagca gttacaattg
      121 caaaagtaat tggagcaaga acaagaaaaa acggatatta tgaggggaat ggatacattg
      181 tttcttggtg tgtaggtcat ttaattcaaa tggcaagtcc agaaagacac gatgaaaaat
      241 ggaagaaatg gacgatagac actcttccta taattccaga ggactatatt tatgaagtat
      301 ctaaaagcac taaaaagcaa tatggagttt taaagaagct tttaaacgat aagaacatcg
      361 acacagttat aaatgcttgt gatgctggaa gagagggaga acttatcttt aggcttgtat
      421 ataatcaagc taaatgtaag aagaaaattc aaagactttg gatatcttca atggaaaaca
      481 aggctattga agatggcttt agaaatctta aagacggaga aaactttgaa gacttatata
      541 gatcagcaag tgcaagagca attgcggatt ggctggtagg aatgaattta agtaggcttt
      601 attcttgcat ttacaaggaa acatattctg ttggtagagt acaaacacca actttatatt
      661 taatagctaa aagggatagt gaaataaacc tatttaaaaa gcaaaaatat tatacagttg
      721 acctatctta tggaggattg aaacttgtat cagataggat tgatagaatt gaagttgcag
      781 aacaactatt aaatctacta gaagatgaaa tagttattac agaggtagaa gataaagagg
      841 taagcacaaa accagataag ccttatgatc tcactacctt acaaagagaa gcaaataaat
      901 attttggata ttcagcaaat gacactttaa atctagcaca agctttgtat gaaaaaaagc
      961 taatcacata tccaagaaca gatagcaggt atttaaccga tgatatggtt actactatga
     1021 aagaattatt agaaggactt gaagatgact ttaaaatcaa tgaatcaaat tttaagtcta
     1081 tttttaattc atctaatgtt acagaccact atgcgattat tcctactata tcaggtattg
     1141 gaaaagccaa agatttatct gatagagaaa gtaaaatcta taatctaata aagaataaat
     1201 tacttgcttc atgttcggat aacttaaagg aatctagtag aaaaatcaga tatgaatatg
     1261 acaagtttaa ctttaatgca agtggcaaga ctataatcga tgaaggttat acaaagtatc
     1321 taaagaccta tggaaaggaa aaacaagaaa atgaattacc agatgtaaag actggagata
     1381 aaattaagct aacttctaaa aaaatatcgg agaaatttac aaaagctcca agtcattata
     1441 atgaagatac acttttaaag gctatggaaa atgcaggagt agaatccttg gataaagata
     1501 tagaagtaga aagaaaaggc ttaggaacac cagctacaag agcaggaatt atcgaaaatc
     1561 ttatccataa ggatctcata agaagagata agaaaaattt acttgtatca gaaaaaggaa
     1621 atagacttgt atcgattgta gaggataagt ttaagtcggc agaaacaaca tctgaatggg
     1681 aaatgaaact tgcaaagatt agctctggcg aagttgataa agaagacttt ttaagagaaa
     1741 ttgaagatag tataagggag cttgtagata ggtacaagaa taatctaaat gaataaggtt
     1801 aaaatattag agcttttcgg cggcataggt gctattagaa aggcttttat taatttaaag
     1861 ataccttat
//
LOCUS       DARYSY010000123         1836 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYSY010000123 DARYSY010000000
VERSION     DARYSY010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1836
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..180)
                     /locus_tag="TVR04_001961"
     CDS             complement(<1..180)
                     /locus_tag="TVR04_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1270616.1"
                     /translation="MAYVNVPKDLTKVKTKVALNLTKRQLIGFTIAGLIGFPVYLMVK
                     KVLPNDLSMLIMIGVS"
     gene            complement(180..437)
                     /locus_tag="TVR04_001962"
     CDS             complement(180..437)
                     /locus_tag="TVR04_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270617.1"
                     /translation="MKIRRKKDNKINLKTLGTIGLPILLIGGYITREIQNRMIIRKIS
                     EVLDNREETNEKVLEIAVNMGKSLEDLDREDIYGLYLEGLE"
     gene            complement(455..1318)
                     /locus_tag="TVR04_001963"
     CDS             complement(455..1318)
                     /locus_tag="TVR04_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270618.1"
                     /translation="MFNIVDKIKEFFSEILIDMIKENLSGMLLDINDKVSTIANEVGK
                     TPSGWNLEVFHFIKSISENVILPIAGLIITAVLCIELIQMVMNKNNMHDTDTFDFFKY
                     MIKMWIAVWLVSHAFDFSMAVFDVAQNLIGKAAGVANASAKVSPGDIANMVDSLKGES
                     IGKLMTIVLETSIVKMIIQGISILITVILYGRMIEIYIYTSVCAIPFATMGNKEWGSI
                     GTNYIRGLFALGLQGLFLLICVGIYAVLVKTLNISDIHKSIFELLGYTLILGITMMKS
                     GSIAKSILNAH"
     gene            complement(1320..1535)
                     /locus_tag="TVR04_001964"
     CDS             complement(1320..1535)
                     /locus_tag="TVR04_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1270619.1"
                     /translation="MEFFTQAVNVLKILVTAIGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(1536..1814)
                     /locus_tag="TVR04_001965"
     CDS             complement(1536..1814)
                     /locus_tag="TVR04_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1270620.1"
                     /translation="MKTTAIDTKEGEKEVANFTIVRKNKEEGKVKKEYIYCNLYGEKA
                     KSVKEFKSGEYIHIFGYFKETKKEDKTFKNFIVKHINKIEKEEKEEEI"
BASE COUNT          520 a          365 c          213 g          738 t
ORIGIN      
        1 agacacacct atcataatta acatagatag gtcattaggc agcacttttt ttaccattaa
       61 atatactgga aagcctatta gacctgcaat tgtaaagcca attaattgtc tttttgttag
      121 atttagagct acctttgttt ttacttttgt taagtccttt gggacattta cataagccat
      181 tattctaaac cctctaagta taagccatat atgtcttctc tgtccagatc ttctaatgat
      241 tttcccatat tcactgctat ttctaagact ttttcattcg tttcttctct attatctaaa
      301 acttccgata tttttcttat aatcattcta ttttgtattt ctcttgtaat atatcctcct
      361 attaaaagta ttgggagtcc tattgttcca agtgttttta aattaatttt attgtctttt
      421 tttcttctaa ttttcatcat cttctccttt tttattaatg agcatttaaa attgattttg
      481 caatacttcc tgatttcatc atagttatac caagtattaa ggtgtatcct agtaattcaa
      541 aaatactttt gtgtatgtct gatatattta aagtcttaac aagtacggca taaattccta
      601 cgcatataag taagaataaa ccttgcaagc caagtgcgaa gagccctctt atatagtttg
      661 ttccaatact tccccattct ttattaccca ttgtggcaaa aggtatggcg caaactgaag
      721 tataaatata tatttctatc atcctgccgt atagaataac tgtaatgagt attgatatcc
      781 cttgaattat catctttaca attgatgtct ctaatactat agtcattaat tttcctattg
      841 actctccttt taggctatct accatattag ctatatcacc cggagaaact tttgcactag
      901 catttgccac acctgctgcc tttcctatta aattctgtgc cacatcaaat actgccatag
      961 aaaagtcaaa agcatgagat acaagccata ccgctatcca catttttatc atatatttaa
     1021 aaaaatcaaa ggtatctgtg tcatgcatat tatttttgtt cattaccatt tgaattaatt
     1081 caatacatag tacagccgtt atgataagac ctgctatggg aagtataaca ttttctgaaa
     1141 tagactttat gaagtggaaa acctccaagt tccatccact tggagtcttt cctacctcat
     1201 ttgctatcgt tgatactttg tcatttatat caaggagcat tccgcttaaa ttttccttga
     1261 tcatatcaat aagtatctcc gaaaaaaact ctttgatctt atctactata ttaaacattt
     1321 tattttaaca cgtttgctaa tagcggtatt agttttaaac ctatgagtac aattccccct
     1381 ccagccataa gctgcttaat accttgagat ttagcaccag ggttgtcatt cccataacct
     1441 tccatcaggt tgataacacc ccatgctcca agccctgcac caattgctgt aactaatatt
     1501 tttaatacat ttactgcttg tgtaaaaaat tccatttata tttcctcctc tttttcttct
     1561 ttttcaattt tatttatatg ctttacgata aaatttttaa atgtcttgtc ttcttttttt
     1621 gtttccttaa aatatccaaa aatatggatg tattctccac ttttaaattc cttcacactt
     1681 tttgcctttt ccccgtagag attacagtag atatattctt ttttaacctt tccttcttct
     1741 ttgttctttc taactattgt gaagttagct acctcttttt ctccttcctt tgtatctatt
     1801 gcagttgttt ttatttctcc tactagattt ccatta
//
LOCUS       DARYSY010000124         1772 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYSY010000124 DARYSY010000000
VERSION     DARYSY010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>1772
                     /locus_tag="TVR04_001966"
     CDS             <1..>1772
                     /locus_tag="TVR04_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1270621.1"
                     /translation="ELGKEENLEDSKLLKKELEELHFQKAKLVEVMPKALDASEITVR
                     MGATWIPEQDYKKFMFDLLKTPVSSRWNIDIKYSDFTGEYRVEGKSSDRDNDLASFTY
                     GTNRVNAYKLIEDTLNLRDTKVFDQVEDSDGKKKSVLNQKETMLARSKQEMIKEEFKS
                     WIFDDVERRNRLVEDYNERFNSIRQREYDGSNLTFEGMNPEIELRAHQKDAIARGLFG
                     GNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFGREFNELYPGANV
                     LCATEKDFTPDRRKRFCSRIATGSFDAVIIGHSQFEKIPISKERQEYELQGQIDEIID
                     YIDEYKRERDQRFTVKQLEKTKKKLETKLEKLNADYKKDDVVTFEELGVDKLFVDEAH
                     AYKNLYLFSKMRNVAGITSTDSQKSSDMLMKCRYMDEITNNKGLVFATGTPVSNSMAE
                     LYTMQRYLQYDELKKMKLQHFDSWASTFGETITAIELNPEGNGYRSKTRFAKFYNLPE
                     LMNTVKGFMDIKTADVLNLPTPIAHYETIKTKPTEEQKEILETFSERADKVRDKQVDS
                     SVDNMLLITNDGKKMALDQRLINP"
BASE COUNT          724 a          215 c          353 g          480 t
ORIGIN      
        1 aagagttagg aaaggaagaa aatctagagg atagtaaact cttaaaaaaa gaattagaag
       61 agttacattt tcaaaaagca aagctagtgg aagtaatgcc taaagcacta gatgcaagtg
      121 agattacagt tagaatgggt gcaacatgga taccggaaca agattacaaa aaatttatgt
      181 ttgatttgtt gaaaacacca gtttcatcaa ggtggaatat agatattaag tattctgact
      241 ttacaggaga atatagagtt gaaggaaaaa gctctgatag ggacaatgac cttgcttctt
      301 ttacctatgg tacaaatagg gtaaatgcct acaaattgat agaagatact ttaaatttaa
      361 gagatactaa ggtatttgac caagtagaag acagtgatgg aaagaaaaaa tctgtgctta
      421 atcaaaaaga aacaatgctt gcaagaagta agcaagagat gataaaagaa gaatttaaaa
      481 gctggatatt tgatgatgtg gaaagaagaa atagattagt agaagattat aacgaaagat
      541 tcaattccat aagacaaagg gaatatgatg gatctaatct tacttttgaa ggaatgaatc
      601 ctgaaataga attaagagca catcaaaaag atgccatagc aagaggtttg tttggtggaa
      661 atactttact tgcccatgaa gtaggagcag gaaaaacatt tgaaatgata ggtatagcca
      721 tggagtcaaa aagacttggg atgagtaata agtcaatgtt tgttgttcct aaccacattg
      781 tagagcaatt tggaagagaa tttaatgaac tttatccagg agctaatgta ttatgtgcta
      841 cagaaaaaga cttcacacca gatagacgaa aaagattttg tagtcgtatt gctacaggaa
      901 gttttgatgc tgttattata gggcacagtc aatttgaaaa aattcctata tcaaaagaaa
      961 gacaagaata tgaattgcaa ggtcaaattg atgaaatcat tgactatata gatgaatata
     1021 aaagagaaag ggatcaaaga tttactgtaa agcaattaga aaaaacaaag aaaaaattag
     1081 agacaaagtt agaaaaatta aatgctgatt ataagaaaga tgacgttgta acctttgagg
     1141 aactgggagt agataagtta tttgtagatg aagcccatgc ctacaaaaac ctctatctat
     1201 tttctaaaat gaggaatgta gcaggaatta cttctacaga ttcacaaaaa tcatcagata
     1261 tgcttatgaa atgccgctat atggatgaaa taactaataa taaaggatta gtatttgcca
     1321 caggtacacc agtaagcaac agtatggctg aactttatac catgcagaga tatttacagt
     1381 atgatgaatt aaaaaagatg aaattgcaac attttgattc ttgggcatct acttttggag
     1441 aaacaataac ggcaatagaa ttaaatcctg agggtaatgg ttataggagc aaaaccagat
     1501 ttgcaaaatt ttataatctt cctgaactta tgaatactgt aaaaggattt atggatatta
     1561 aaacagctga tgttttaaat cttcctacac caattgccca ttatgaaact ataaaaacaa
     1621 agcctaccga agaacaaaaa gaaattcttg aaactttttc cgagagagca gataaggttc
     1681 gtgataagca ggtagattca agtgttgata atatgctatt aataacaaat gatgggaaga
     1741 agatggcatt agatcaaaga ttaatcaatc ct
//
LOCUS       DARYSY010000125         1746 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYSY010000125 DARYSY010000000
VERSION     DARYSY010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1746
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            130..591
                     /locus_tag="TVR04_001967"
     CDS             130..591
                     /locus_tag="TVR04_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEL1270622.1"
                     /translation="MSNIEVFKIPIPSDNEGFIVLKCPICSEKFMIQVQDANDDSLID
                     VWCPKCGLKSDNYLDDDVNDLAENIIQNYVADLLNDFSKDMEKTFRNNKNIQFKGSKK
                     IAKESEMPIGRKVGDFEEQKYLCCDKVVKLRTTTKFEGGYCPFCGELVDGD"
     gene            581..1384
                     /locus_tag="TVR04_001968"
     CDS             581..1384
                     /locus_tag="TVR04_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1270623.1"
                     /translation="MEINKKELRKISRRFRTLASNVMNAYFEEQTDALIEFLDYIKRT
                     SLIFDYVESLAYDIEGLESELDRIASSYGSKALELGTDSRRRTYLLYRAFDYIALKKL
                     STTNFGWYYAHSKKYQDMAKAFGDRLIYPFVLEIEEYIKDIATDMGFDNDSSYNITIN
                     SSGVQVNIAEHGGTVNAEQGNIINKEELSRAIKNVENAIETVENSESKSVLKQNLEIV
                     KNEVQEVQPKKAILTSAFNTMKFIATTVALTPDLAEGIKLLASVIGISI"
     gene            1499..>1746
                     /locus_tag="TVR04_001969"
     CDS             1499..>1746
                     /locus_tag="TVR04_001969"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270624.1"
                     /translation="MQPIECEFYYAGIKVYTEAQELIFKDIVGSSDVLNIDEAKAKNR
                     PKIIAIADVISFLIGYTLTIYDIESQSYSVESSKETME"
BASE COUNT          659 a          193 c          345 g          549 t
ORIGIN      
        1 tttcaagttt atcaaatgag aagcaacaaa agttaatttc ttcgtttaat gagattacta
       61 aaaatatgaa ctaagttgaa agcttgtcaa taaaccgtag ctttagaaaa ataaagaaaa
      121 gaggctttag tgtcaaatat tgaagttttt aaaataccta ttcctagtga taatgaagga
      181 tttattgttt taaaatgtcc aatttgtagt gaaaaattta tgattcaagt ccaagatgca
      241 aatgatgata gcttgataga tgtttggtgt cctaagtgtg gactcaagag tgataattat
      301 ttagatgatg atgtaaatga cttggcagaa aatataattc aaaactatgt tgctgattta
      361 ttaaatgatt tttcaaagga tatggagaaa acatttagaa ataataaaaa tatacaattt
      421 aaaggaagta aaaagatagc taaggaatca gaaatgccaa ttggaagaaa agttggagac
      481 ttcgaagagc aaaaatactt gtgttgtgat aaagtagtaa aattacgaac tacaacaaaa
      541 ttcgaaggtg gttattgtcc gttttgtggg gagttagtag atggagatta ataaaaaaga
      601 acttagaaaa attagcagaa gatttagaac attggcttca aatgtgatga atgcttattt
      661 tgaagaacag acagatgcat taatagaatt tctagattat attaagagga catctttgat
      721 atttgattat gtcgaaagtt tagcttatga catagagggg ttagaatcag aacttgatag
      781 gattgcttcc tcatatggaa gtaaagcttt agaactgggg actgatagcc gtagaagaac
      841 ttatctttta tatagagctt ttgactatat tgcccttaaa aagttgtcta caactaattt
      901 tggatggtac tatgcacata gtaaaaaata tcaagatatg gcaaaagcat ttggagatag
      961 gttgatttat ccatttgttt tagaaattga ggagtatatt aaggatattg cgacagatat
     1021 gggatttgat aatgacagtt catataatat aacgattaat agttcaggag tacaagtaaa
     1081 tattgccgaa catggtggta cagtcaatgc tgagcaagga aatatcatta ataaagagga
     1141 actttctaga gctataaaga atgtggaaaa tgctattgaa acagtagaaa atagtgagtc
     1201 taaatcagta ctcaagcaga acttagagat tgttaaaaat gaggttcaag aagtacaacc
     1261 taaaaaggca attttgactt cagcttttaa tacaatgaaa ttcatcgcaa ctacggttgc
     1321 cttaaccccc gacttagcag aaggaattaa attgcttgcc tcagtaattg gaatcagtat
     1381 ttaaaggttt tatcgttcat gattagggat aatgattgtg aggttactat attgttgagg
     1441 gatattcatg atatattaca gtgagataca cttcaggttt aatcaactag agacctattt
     1501 gcaaccaatt gaatgtgaat tctattatgc aggaattaag gtttacacag aggcacaaga
     1561 acttatattt aaggatattg taggtagttc tgatgtcctt aatatcgatg aagcaaaggc
     1621 aaagaatcga cctaaaataa tagctattgc cgatgttatt tcatttttaa tagggtatac
     1681 tttaacgata tatgatatag agtctcaaag ttatagtgtt gaatcttcaa aagaaacaat
     1741 ggaaat
//
LOCUS       DARYSY010000126         1721 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYSY010000126 DARYSY010000000
VERSION     DARYSY010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1143
                     /locus_tag="TVR04_001970"
     CDS             <1..1143
                     /locus_tag="TVR04_001970"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270625.1"
                     /translation="DLLRDLKNGNFEKILDWWKAQSVLYEMNNTKYRAWHNGSYGELP
                     SLYSTPTLISFHDIGGVEIMLESLLLAKGTSNSRVIFEEARNGLIKLRDEVYAGGSGD
                     YHSIIAGEESVDFILSKSDKQVRNLELKVKNSEIPIGDVFNGKLGIYLVLASYSRTCL
                     DTMVQGEIELANSSSDYSKFGLAHGKLGELWTKFRIYAKLDLNKECMRIYSETLKCYK
                     NGKILPGWCNGYSGLLMVLVEMSKVLNIKIDYFELALKCVDLPENASIDLSVCHGTSG
                     VIQSLLFCYIVTKDKRYIELADSYWNLVYKKAQSDGFYIGESNREYLLGYMMGWSGVI
                     DTILLLNLLKDGRQHWIPLNLSTIDYQEQLKKETFNVIGCSVKSKA"
     gene            1109..>1721
                     /locus_tag="TVR04_001971"
     CDS             1109..>1721
                     /locus_tag="TVR04_001971"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270626.1"
                     /translation="MLSVVALNPKHDIINKAFNVVYINFGNIQIPFGLIEFEQPVFDL
                     NDPKNDDYLLIKVNSFSCNYRDKAILVNNFEQLLRLGKPFLPFGSEFSATIVLKGKNV
                     DEFGIGDKVIPNCTYEGVTNDNVVPGVTTNFASLGWLRIRREKLIKQPHELSDLEAAC
                     FSLGAQTAYSMIRKSGILEKQNKKAVVFSSRSVTSLFIIQLLNY"
BASE COUNT          595 a          208 c          354 g          564 t
ORIGIN      
        1 gatttactta gggatttaaa aaatggaaac tttgaaaaaa tattagactg gtggaaagct
       61 caatccgttc tctatgaaat gaataacaca aaatatcgag cgtggcacaa cggttcttat
      121 ggtgaattac cttccctata tagtactccc actttgatat ctttccatga tataggtggt
      181 gttgaaatta tgttagaaag cctgttatta gctaaaggca cctcgaatag tagagttatt
      241 tttgaagagg ctcgaaacgg tttaataaag ttaagagatg aggtatatgc tggtggtagt
      301 ggtgattacc attcaattat tgctggagaa gaatccgtag attttatact ttctaaaagt
      361 gataagcaag taaggaattt ggaattaaaa gtaaaaaata gtgagattcc aatcggagat
      421 gtattcaatg gtaaattagg aatatattta gttttagcaa gttattcaag aacatgcttg
      481 gatacaatgg tacaaggaga gattgaatta gcaaattcat ctagcgacta ctcgaaattc
      541 ggtttggccc atggtaaatt aggtgagtta tggacaaaat ttagaattta tgcaaagtta
      601 gatcttaaca aagagtgtat gaggatatat agcgaaactc ttaaatgtta taagaacgga
      661 aaaatattac caggttggtg taatggttat tcaggtctct taatggtttt ggtagaaatg
      721 tcaaaagtac taaatataaa aattgattat ttcgaacttg cattaaaatg tgttgactta
      781 cctgaaaatg cgtcaattga tttatcagtt tgccatggaa caagcggagt catacaaagt
      841 ttattgtttt gttatattgt aacaaaggat aaaagatata ttgaactagc tgatagttat
      901 tggaatctag tttataaaaa agcgcagagt gacggttttt atattggaga aagtaacaga
      961 gagtacctat taggttatat gatggggtgg agtggtgtga ttgacacgat attattacta
     1021 aacttattaa aagatggaag acagcattgg attcctttaa atctaagtac tattgactat
     1081 caggaacaat tgaaaaagga gacattcaat gttatcggtt gtagcgttaa atccaaagca
     1141 tgatataatt aacaaggctt ttaatgtcgt atacattaat ttcgggaata tccagattcc
     1201 atttggctta atagagtttg aacagccagt atttgattta aatgatccca aaaatgacga
     1261 ttatttattg ataaaagtta actcattttc gtgtaattat cgagacaaag ctatattggt
     1321 aaataacttt gaacaattgc ttcgtttagg aaagccattc cttcctttcg gatctgagtt
     1381 tagcgctact attgtattaa aagggaaaaa tgtagatgag tttggcattg gtgataaagt
     1441 aattcctaac tgtacttatg aaggggttac taatgataat gttgttccag gtgtgacaac
     1501 taattttgca tcattaggct ggttgagaat taggagggag aagcttatta aacagcctca
     1561 tgagttgtcc gatttagaag cagcttgctt tagtttaggt gcacagactg cctacagtat
     1621 gattaggaag tctggaatat tggaaaaaca gaataaaaaa gcagtagtat ttagttcaag
     1681 atcagttact tctctattta taattcaact tttaaattat t
//
LOCUS       DARYSY010000127         1699 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYSY010000127 DARYSY010000000
VERSION     DARYSY010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1699
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(58..1335)
                     /gene="serS"
                     /locus_tag="TVR04_001972"
     CDS             complement(58..1335)
                     /gene="serS"
                     /locus_tag="TVR04_001972"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1270627.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITSIIT
                     VLPNTPHDSVPIGADEEDNVEIRRWGRPRQFDFDIKAHWDLGEALNILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTSFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAENILQKLELPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLELIKPR"
BASE COUNT          466 a          383 c          384 g          466 t
ORIGIN      
        1 agaaagatag agcccattaa ttgtcgtgct gacgccttat tcggtcagtc tttggcttta
       61 gcgtggcttg ataagctcta atcctcccat ataaggacga agcacttctg gaatcgtcac
      121 tgagccgtcc tcattttggt aattttctag gatagcagct acggtacgcc cgacagcaag
      181 cccagagcca tttagggtgt gtagcagctt aaccttgccg tctgcctcat cgcggtagcg
      241 aatttgcgcg cgtcgtgctt gaaaatcttc ggtatttgag cagcttgaga tttcgcgata
      301 ggtgttttga gcagggatcc aaacctctaa atcataggtt ttagcggccg aaaagcccat
      361 atccccagta caaagagcca agacacgata agggagctct agcttttgga gaatattctc
      421 ggcattggcg gtcatttttt ccagctcttc ataagatgtt tcgggcttag caaacttaac
      481 catttcgacc ttatggaatt gatgtaagcg aatcaagcca cgagtgtcgc ggccagcaga
      541 gccagcctca gagcgaaatg atgggctcat tgcagtaaag tagattggca gctccttacc
      601 atctatgatg tcaccgcggt agtaattggt tagtggcacc tcagcagttg ggataagaac
      661 aaagcttgtc ccatctagct caaaggtatc ctccttgaat tttggatatt gaccagtgcc
      721 aaacatagag tcatgattaa ccatataagg aggaatgatt tcctgatagc cctcttttag
      781 gtgctcatca agcatgaagt tataaagggc acgctccagc cttgcgccaa gatttttata
      841 gaataagaag cgcgcaccag taacctttgc gccacgctcc caatcaagga tatttaaggc
      901 ttctccaaga tcccaatgcg ccttgatgtc aaagtcaaac tgacgtggcc ttccccagcg
      961 acgaatctct acattgtcct cttcatcagc tccaatagga actgagtcat ggggagtatt
     1021 tggcaaaaca gtgatgatac tagtgatttc ttggtcaatg tcagctagct tagcatcaat
     1081 tgccttgatg ttagcagcta gctgttgcat gtcagcaatc tgttggctgg cgtcttcctt
     1141 ttggcgtttg gcctgagcga tagcagcaga ggcgatatta cgctgggctt ttagctcttc
     1201 tgtttgaaca agcagggtgc gccgctgttc atctaaggct tttagagagg ttaggatagc
     1261 ttctgacaca ccacgtgttt tgagcttagc agcaacagta tcaaaatcag tacggatacg
     1321 cttaagatct agcataaata aatctccttt gagctggtga taagatagtc agttataaaa
     1381 tagcatgagc aaagctagct gatcgctttt ttatttctga cgagataaaa aagcacagcc
     1441 tatgaataca ctggagcgcc taagcgcggt tccatccagc ttcacaatct gtgcacttaa
     1501 ttcctattca attggtagac ggtagaattt cgtatgaccc ctctatctgt tttcagcaac
     1561 cacagacttt ctgaaagaca gagccagact acttatccgc tagacctatt ataacaaaaa
     1621 aagagaaaaa gtaaactccc aaatgagtgt cagctacatc aaacgcgcga actagttatt
     1681 ttggaattag agtagacac
//
LOCUS       DARYSY010000128         1686 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYSY010000128 DARYSY010000000
VERSION     DARYSY010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1549
                     /locus_tag="TVR04_001973"
     CDS             <1..1549
                     /locus_tag="TVR04_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002839222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEL1270628.1"
                     /translation="GELEKSKSKLKDNILKNKTKGSLSSGVLLSGAKSSELVRDYLSS
                     GSDNTGVESGEKAANVSSKLQHGIRKYKIDKKKKSLKKLSKLDKKIRNRKSKLEFKSG
                     LEDLKKSDAYIKKNRFKKFYQRKQMKSMIAKKHETRLVDRVKKAILSLGKASKELIVR
                     KSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTVLSEVNQEFSS
                     MEYDLQSQIESVKTSHPGYDEYIINKEGEIGHNTHELLSYITSRCGEVKSASEVKGIL
                     KELFDKMYKLDFKEEIEIRTRTVARTRYDSRGNPYTSYEKEEYEYKKLIITLKKKEMD
                     EVVREIFEDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIVDNPNFGNPGLAFDSAT
                     AKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCN
                     PVSPSEAQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHF
                     YGFGRPR"
BASE COUNT          689 a          208 c          344 g          445 t
ORIGIN      
        1 tggagagctt gaaaagtcta aaagcaagct aaaggataat atcttaaaga ataaaactaa
       61 aggaagtcta tcttctgggg ttttattatc tggagctaag tcttcagagt tagtgagaga
      121 ttatctaagt tcaggatctg acaatactgg tgtagaatct ggagaaaagg ccgctaatgt
      181 aagctctaaa ctccagcatg gaataaggaa gtataagata gacaaaaaga aaaagtcctt
      241 aaaaaagcta tctaaacttg ataagaaaat aagaaataga aaaagcaagt tggagtttaa
      301 aagcggcttg gaagatttaa aaaagtcaga tgcctatata aagaaaaata gatttaagaa
      361 gttttaccaa agaaagcaaa tgaagagcat gatagctaaa aagcacgaaa caagacttgt
      421 agatagagtt aaaaaagcta ttttaagttt aggtaaggct tctaaagagc taatagtaag
      481 aaaaagcaag atggttctat ttctagtaat agggctaggt cttatgctat caatcatgat
      541 tggtggcgga agtgttggta tgagtggact aagcaattca gtaaactcag taatgacaac
      601 aacataccta tcacaagaca cagttctaag tgaagttaat caagaatttt catcaatgga
      661 gtatgaccta caatcacaaa tcgaaagtgt gaaaacaagt catcctggat atgacgaata
      721 tatcataaac aaagaaggag aaattggtca taatacccat gaacttttat cctatataac
      781 ttcaagatgt ggagaagtaa aatcagcatc tgaagtaaaa ggaattttaa aagaactttt
      841 cgataagatg tataagcttg attttaagga agaaattgaa attagaacaa gaacagtagc
      901 aagaactaga tatgatagtc gtggcaatcc ttatactagc tatgagaaag aagagtacga
      961 atataaaaag ttaattataa ctttaaagaa aaaagaaatg gatgaagttg ttagggaaat
     1021 atttgaagat tatccagaca atgtagttca ttatgaagct cttcttgaag ctaaggggaa
     1081 tatgggagat gtttttggat caggtaatgg ggacttagga gaaatagtag acaatccaaa
     1141 ctttggaaat cctggtcttg cttttgattc agccactgcc aaagccttat ttaatgaagc
     1201 agaaaaacat ataggcaaaa gatatgtgtt tggagcaagt ggaccatcta actttgactg
     1261 ttcaggtttt gtatgttggt catttacaaa gtctggtgta aagagaatgc caagaacaac
     1321 tgcatggaga atatacaaag actattgtaa tccagtaagt ccaagtgaag ctcaacctgg
     1381 agatattata tttttccatt caacatataa cagtggaact ccaatatctc atgtaggcat
     1441 atatgcaggt aacggaatga tgattcacgc aggagatcca attcaataca catcaataaa
     1501 ttcaaaatat tggaaatcac acttttatgg ttttggaaga ccaagataga agggagatat
     1561 tatgtgaata ggaagcttat aagtattaga aacaaaaaga aaaaaataga agagaaatta
     1621 aaagatttaa atgcaaaata caaggaaatt tgcgatgaag aaatacaagt tgaaaatgaa
     1681 gaaata
//
LOCUS       DARYSY010000129         1675 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYSY010000129 DARYSY010000000
VERSION     DARYSY010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..944
                     /locus_tag="TVR04_001974"
     CDS             <1..944
                     /locus_tag="TVR04_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA helicase"
                     /protein_id="HEL1270629.1"
                     /translation="DSKVIGKYRNLDLQVSYNFMTNTHTFKLLGKAEYFGEFSNSTDG
                     NITRLDNAIEKMPARLDRLNQNLEKYKESLENAKVELTKPFEKADELRDKTLRLAEIN
                     KLLDMGEVEELENQSPLLEDLKRAIVDYSNYEFSESNSYEDFDKLYPDLSHIGLAYTE
                     TPDGKHTIQYEVNLEEKTWTQYVDNVAIRTESFVEEDISNSQAIKDMTEAIKMSSFDD
                     LVSVDEENLKQALGLEIDDDGNFYDPLAKDLDNDGIPDRYDNDFKDSDYFESIYDVED
                     NLHAREEKPSILGQISKFKSEEEKDKNQEKNEKGQER"
     gene            988..1644
                     /locus_tag="TVR04_001975"
     CDS             988..1644
                     /locus_tag="TVR04_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1270630.1"
                     /translation="MEYKDIRENLEEMMNDNYKDFIKALVSIEKGVNDEKALEEVYVL
                     YMNNDTTGLLSDDFDYMIDDMKEQGKIVENVSDIEEKDELINLVGNIVGKVENLEREN
                     TNGEKFKVSNFSIVSKDNDGNKVYTNCSAYGDKTKDLENLKKGDFVKIFGQVKTSIDK
                     NGKEHKNVRILSSKLLKAKEQVRSQDKDKKSILGQIKSFKTDDKAKSNKKVHSKGTER
                     "
BASE COUNT          723 a          187 c          323 g          442 t
ORIGIN      
        1 atgatagcaa ggtcattggt aaatatagaa atttagactt acaagtttca tataatttta
       61 tgactaatac tcacaccttt aaactcctag gaaaagcaga atattttgga gagttttcaa
      121 actctactga tggtaatata acaaggcttg ataatgccat tgaaaaaatg cctgcaagac
      181 ttgataggtt aaatcaaaac cttgaaaagt ataaagaatc tttagaaaat gccaaagtag
      241 aattgacaaa accatttgaa aaagcagatg agttaaggga taagacatta agacttgctg
      301 aaatcaataa acttttagat atgggagaag tagaagaatt agaaaaccaa tcaccattat
      361 tagaagattt aaagagggcg atagttgatt attctaacta tgagttttca gaatctaata
      421 gctatgaaga ctttgacaaa ctatatcctg atttaagcca tataggactt gcctatacag
      481 aaacacctga tggtaagcac acgattcaat atgaggtaaa tttggaagaa aaaacatgga
      541 ctcagtatgt agataatgta gccattagaa cagaatcttt tgtagaagaa gatatatcaa
      601 attcacaagc tattaaagac atgactgaag ccataaagat gtctagtttt gatgatctgg
      661 tatcagtaga tgaagaaaat ttaaaacaag cactaggact agaaatagat gatgatggaa
      721 acttctatga tccactagca aaagatcttg ataatgatgg aataccagat aggtatgaca
      781 atgattttaa agatagtgat tactttgaat caatatatga tgtagaggat aatcttcatg
      841 caagagaaga gaagccatca atattggggc aaatatcaaa attcaaatct gaagaagaaa
      901 aagataaaaa tcaagaaaaa aacgaaaaag gacaagaaag atagaggaga gcgaaaggct
      961 ctccttatta agtacaagga ggaaattatg gaatacaaag atattagaga aaacttagaa
     1021 gaaatgatga atgataatta caaggacttt ataaaagcac ttgtgagcat agaaaagggt
     1081 gttaatgatg aaaaggcact tgaagaagtc tatgttttat atatgaacaa tgacacaaca
     1141 ggtctactaa gtgatgactt tgactatatg attgatgata tgaaagaaca aggtaagatt
     1201 gttgaaaatg tcagtgatat tgaagaaaaa gatgaactta taaatcttgt cggtaatata
     1261 gttggaaaag tagaaaatct tgaaagagaa aatactaatg gagaaaagtt caaggtaagc
     1321 aacttttcaa ttgtttcaaa agataacgat ggaaataaag tttataccaa ttgttcagct
     1381 tatggagata agacaaaaga tttagagaat ctaaaaaaag gagattttgt taaaatattt
     1441 ggtcaagtaa aaacaagtat cgataaaaac gggaaggaac ataaaaatgt tcgtattttg
     1501 tcttctaagc tcttaaaagc aaaagaacaa gtaaggagtc aggataaaga taaaaagtcc
     1561 atattagggc aaataaaaag cttcaagaca gatgacaaag ctaagtcaaa taagaaagtt
     1621 catagcaaag gtacagagag ataatattta aagggttgag aaaaatacta tttat
//
LOCUS       DARYSY010000130         1637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYSY010000130 DARYSY010000000
VERSION     DARYSY010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            263..940
                     /locus_tag="TVR04_001976"
     CDS             263..940
                     /locus_tag="TVR04_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270631.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQASKK
                     NIEKQKALTSNLFIVASCLSPVTVAGLLMLSRSFPIFDKALTAQIDTYAPIILGVVLF
                     FAFETLMLAIRGRDPLAEREPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            947..1261
                     /locus_tag="TVR04_001977"
     CDS             947..1261
                     /locus_tag="TVR04_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1270632.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
BASE COUNT          473 a          274 c          331 g          559 t
ORIGIN      
        1 tttatcagta ccttatgtag gtctatacat tactttcttt ctaatttttt taatcattcc
       61 actttgttat catttttact tgcacccatc ttcatttggg gattatctcg ctgcattatc
      121 tgtaacaagt ttgttgattt ccttatttcc caatttttta tggaatggtg tcttgaagca
      181 cgttatatat gtcaaactta ttcgccaaac aaaagaaaga attttagaga atgaaagcta
      241 aacaatcagg aaggagctta gcatggtaat gttaatgaga acactgttat tcccagttga
      301 taatggtatg ggaacgggct tgaccggtga tggttatgcg gctgagtatg atctatggac
      361 tggaaaggtc acgtggcgac aagccagcaa aaaaaacatt gagaagcaaa aagcactgac
      421 ttccaatctt tttattgtag cctcatgctt atcaccagtt actgttgcag gactattgat
      481 gttgagtaga agcttcccta tttttgataa agctctaaca gcacaaattg atacctatgc
      541 tccaattatt cttggtgttg tgttattttt tgcttttgag acgttaatgc ttgctatcag
      601 aggtcgtgat ccattagcgg agagggaacc agatttaaag cggcagcatg actattttga
      661 aaagatgttt gattttgcta ttcgtagaaa tttgtcgtca gataatctaa aaactcctta
      721 tatagctact tattttgcct ttggtatttc tttactctgt attccattta gctattatgt
      781 ttatctgaat ccggagcaat tccctaattt ggattatggt catttatcaa tcctgcttgt
      841 aacaagtatt cttatttccc tagttcccaa ctttttatgg aatgttctat taaagcacat
      901 tatctatatc aagcttattc gcaaaacgaa aggacaataa aacattatga acaaaccaga
      961 acacatttta ccgattggta ctatagtgct gacggagaca ggagaaattc ctttgatgat
     1021 tgtgagtcgt gcctctcttt ttgatgataa tggagaaatc ggctattttg attatgctgc
     1081 agttccttat ccagaaggca taggaaatga taatgagtac cttttcttca accatgagga
     1141 tattgctgat gtcatctatt ttgggtatgt caattccaat gaacagcttt ttgcagaagc
     1201 ctacgatgat ttggtgaaaa catcaggtta tcgtaaatta agcttagatc accatcaata
     1261 gaaaaagaat gcgaagagca tctgaaaaaa ggggagagtt gatgagtatt gacatgtatc
     1321 tggggtcgtc ggaccagcag gctaacgatg tatgaccaat attttgagag gatcggcctg
     1381 ctcctctttt ttgtatgttc aaagtcataa aaggcttact ttttgaggta taaagcttcg
     1441 acaattaaga gtatttgctc tagtggtctt aatgatcttg cttatagctt ctggtcagat
     1501 tgttttagcc tgcttgtgct gtctgatcca gatttgacta aggctttgat gacagtcgtg
     1561 aaggcgggtt taagagcggc atgtctaacg ttaattcaca acggagaagg aaaattgacc
     1621 aaacagtgtg agatatt
//
LOCUS       DARYSY010000131         1628 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYSY010000131 DARYSY010000000
VERSION     DARYSY010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1607
                     /locus_tag="TVR04_001978"
     CDS             <1..1607
                     /locus_tag="TVR04_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEL1270633.1"
                     /translation="GTLSYIPSLNPRDLLVGVSVAALVKLIVYIKGKNKKKYRQGKEY
                     GSARWGESKDIAPYIDPKFENNVLITNTERLTMNSRPKNPKYARNKNVLVIGGSGSGK
                     TRFYVKPNLMQMHSSYVVTDPKGTLVLECGKMLYENGYDIKILNTINFKKSMKYNPFA
                     YLRSEKDILKLVQTIIANTKGDGEKAGEDFWVKAEKLYYTALIGYIYYEAPEEEKNFK
                     TLLDMIDASEVREDDETYMNPIDRLFEALEKKDPSHFAVKQYKKYKLAAGKTAKSILI
                     SCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISDTDDTFNFVVSIMYSQLF
                     NLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQAQSQ
                     LKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKETIDLYNTSETRSNQKSFG
                     LNYQKTGKELMSQDEITVMDGGKCIYQLRGVRPFLSDKFDITQHKNYKLLEDYDKKNL
                     FDVEEYLTNRDKVKLKSSYKINRLNI"
BASE COUNT          640 a          218 c          310 g          460 t
ORIGIN      
        1 taggaacttt atcttatata ccaagcctta atccaaggga cttgttagta ggtgtttcag
       61 ttgctgctct tgttaagcta attgtttata ttaaaggtaa aaataaaaag aaatataggc
      121 aaggtaagga atatggttct gcaagatggg gagaaagcaa ggatattgct ccatatattg
      181 accctaagtt tgaaaacaat gtactaataa ctaataccga aagactaaca atgaactcaa
      241 gacctaaaaa tcctaaatat gctagaaata aaaatgtatt agtaataggt ggttctggat
      301 caggtaaaac gagattttat gtaaagccaa atctaatgca gatgcactct tcctacgtag
      361 taacagaccc taaaggcacg cttgtgttag agtgtggaaa aatgctttat gaaaatggat
      421 atgacataaa gattttaaat acaataaact ttaaaaaatc tatgaaatat aatccatttg
      481 cctatttgag aagtgaaaaa gatattttaa agcttgtcca aacaattatt gctaacacaa
      541 agggagatgg agaaaaggca ggagaagatt tctgggtaaa ggctgaaaag ctatattaca
      601 ctgcccttat cggttatata tattatgaag cacctgaaga agaaaagaac tttaagacac
      661 ttttggatat gattgatgca agtgaggtta gagaagatga cgaaacctat atgaacccaa
      721 ttgatagact ctttgaagct cttgaaaaga aagacccaag tcattttgca gttaagcaat
      781 ataagaaata taagctggca gcaggaaaaa ctgccaagtc aattctaata tcttgtggag
      841 caagacttgc accttttgat ataagagagc ttagagagtt aatgagcgaa gatgaactag
      901 agcttgataa aattggagat aggaaaactg ctctattcgt aataatatca gatactgacg
      961 atacttttaa ctttgtagta tcaataatgt attcccaatt atttaatcta ctatgtgata
     1021 aggcagatga tgtgtatggt ggaagacttc cagttcatgt taggtgtcta cttgatgagt
     1081 ttgcaaatat cggtttgatt cctaaatttg aaaaattgat tgcaacgatt cgttcaagag
     1141 aaatatcagc aagcataata ctgcaagcac aatctcaatt aaaagcaatt tataaagacc
     1201 atgcagatac aatagttggt aactgtgact ctacactctt tctaggagga aaagaaaaaa
     1261 caacagtaaa agaattatca gaaaccttag gaaaagaaac catagaccta tataacacat
     1321 cagaaacaag atccaatcaa aaatcttttg gtttaaatta ccaaaaaact ggtaaggaac
     1381 ttatgagtca agatgaaata actgtaatgg atggcggtaa gtgtatatac caactaagag
     1441 gagtaagacc tttcttgtct gataagtttg atattacaca gcataagaat tacaagttgt
     1501 tggaagatta tgataagaaa aacttgtttg atgttgaaga gtatctaaca aatagagata
     1561 aggtaaagtt aaaatcaagt tataaaataa ataggttaaa catctgattt tatggagaaa
     1621 gcaaaatg
//
LOCUS       DARYSY010000132         1625 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYSY010000132 DARYSY010000000
VERSION     DARYSY010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1625
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(37..327)
                     /locus_tag="TVR04_001979"
     CDS             complement(37..327)
                     /locus_tag="TVR04_001979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270634.1"
                     /translation="MTTDKECNSIAKEVYRVDSSKVDNPIKDRDTLASGKYKVLKAED
                     NPDNGMQARVPKRNGNVLALNYKLRRFYDSKKESHHFIRNRSNFSNGRYIYV"
     gene            complement(337..732)
                     /locus_tag="TVR04_001980"
     CDS             complement(337..732)
                     /locus_tag="TVR04_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270635.1"
                     /translation="MMNKRRKLIGIVALIAILGGVITMNWLNDERLKKEKYRQEQDRV
                     INYLVEHYELANGDDIKTIEVTEFQQIKIVDFWSITTKVNGKYKISFTEDQLGEEITT
                     SNYSPKEFKVQEDTDNKQNLSDIELIYYD"
     gene            complement(748..1008)
                     /locus_tag="TVR04_001981"
     CDS             complement(748..1008)
                     /locus_tag="TVR04_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270636.1"
                     /translation="MNITDKQYKNLSDEVYNLDPGNKKYNPSLKEEVIFRTGNTNFKI
                     LKAEDTSNSGMQARTVGAIKGGEVDKSHIIIVYAGINHLTAT"
     gene            complement(1005..1385)
                     /locus_tag="TVR04_001982"
     CDS             complement(1005..1385)
                     /locus_tag="TVR04_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270637.1"
                     /translation="MLIKHKGIIVVLLIGLLIGGKITMDKWRDKELLLVEKRLVQALK
                     NTFADIQTIKIDKCDQNDVTGSYGMNITMTNIEGQTVSFFLTFWKNNNEIGTYTITNE
                     QLQKEGKTKTSVKVIYSNGLEDEQ"
BASE COUNT          455 a          338 c          192 g          640 t
ORIGIN      
        1 tgtcgttcta gtatttgctc ttgattctga ttatagctaa acataaatat acctcccatt
       61 actaaaattg ctacgattcc taataaaatg atgactttct tttttactat cataaaacct
      121 ccttaattta taatttaagg ctagcacatt cccattcctc tttggcaccc tagcctgcat
      181 accattgtcg ggattgtctt cggcttttag gactttgtat ttgccacttg ctaaggtatc
      241 tctatcttta atggggttat ctaccttgct agaatcaaca cgataaactt ctttagcaat
      301 actattacat tctttatcag ttgtcatagt tactccttaa tcatagtaaa ttagctcaat
      361 gtcggataga ttctgcttgt tatccgtatc ttcctgtact ttgaattctt taggtgagta
      421 attagaagtc gtaatttctt ctcccaattg atcctctgta aacgaaattt tatactttcc
      481 attcactttt gtagtaatac tccaaaagtc cactatctta atttgctgaa actctgtcac
      541 ttctatcgtt tttatatcat caccgtttgc caattcataa tgttcaacca gatagttaat
      601 taccctatcc tgttcttgtc tgtacttttc cttttttagc ctttcgtcat taagccagtt
      661 catcgttatt actcctccta aaatagctat taaagccact atgccaatta gttttcgtcg
      721 tttgttcatc atcaactcct ttaattgtta ggttgctgtt aaatgattaa ttccagcata
      781 gacaattatg atatgactct tatccacctc gccaccctta attgctccaa ccgtcctagc
      841 ctgcatacca ctgttagagg tatcttcggc tttgaggatt ttgaagttcg tattaccagt
      901 tctaaatata acttcctctt ttaaactagg attatacttt ttattaccgg ggtccaaatt
      961 atagacttca tcacttaaat ttttatattg cttatcagta atattcattg ctcatcctcc
     1021 aagccattag aataaataac ctttacacta gttttagttt taccttcttt ttggagctgt
     1081 tcatttgtta tagtgtacgt tccaatttca ttgttatttt tccaaaaagt taaaaaaaac
     1141 gaaacagttt ggccttcaat atttgtcatg gtgatattca ttccataaga acctgtaaca
     1201 tcattttgat cacatttatc aattttaata gtctgaatat cagcaaaagt atttttcaag
     1261 gcttgcacta accgcttttc aaccaacagc agttctttat ccctccattt atccattgta
     1321 atctttcctc ctatcagtaa tcctattagc aaaactacaa taatgccttt gtgttttatt
     1381 aacattattt atcctcatct aatgacataa tcaagtaaac ttaatccact aaattcctat
     1441 atttttcatg taaaagtgat acactcttat tccttcaaat atgctagagc tattttttgt
     1501 tataacaatt tggggaattg gtatatttgt tgctttttca tcatcaactc ctttaattgc
     1561 taaattgctg ttaaatgatt aattccatca taaacaatca cgatataatt cttacccacc
     1621 tcacc
//
LOCUS       DARYSY010000133         1589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYSY010000133 DARYSY010000000
VERSION     DARYSY010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1589
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(178..1428)
                     /locus_tag="TVR04_001983"
     CDS             complement(178..1428)
                     /locus_tag="TVR04_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1270638.1"
                     /translation="MAKKEMKYYLRKSAFGLASVSAALLVGTASVSAQPFTRGEKQKV
                     ITELKKELEEFKKQYPMANTDIEASLQGMYSLDEMKAKVEEIKMKAVEEAAKAEAEAE
                     AARQKAEEERLQNAWEEAANEALRKEKSTVIYIFGSKQGMTLPQELLDAAKMPESVVV
                     KKGEKVPLPTFGNVRTATGEWRFTGWSRYTNDGETKLTEGYTAPGDGDITLIGDWEFV
                     PFNANVLVSYVDTEGNVLGETVAVSQGLPGEAYDTTSLRLDKIEKDGKVYKFKKLQEG
                     SPSETGTTLEGDLRVVYVYEEVKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPQPKPAPKPEAKKEEKKPAPKQEAKKLPSTGEATHPF
                     FTAAALAVMASAGVVAVSTKRKED"
BASE COUNT          379 a          368 c          291 g          551 t
ORIGIN      
        1 tacccactac agttgacatg gagccaaaag tactcaccct ctatgaggac cagcaggtaa
       61 acctgataaa aaaactaaaa agccaccatt tctgatgact tcttagtcgg cctcttcaac
      121 aacttgtagc ttacacaagc tatagcgcta aggacagcct ttcatcggag cacaacatta
      181 gtcttccttg cgttttgttg ataccgcaac cacacctgca cttgccatga ctgcaagagc
      241 tgctgctgtg aagaatggat gtgttgcttc acctgttgat ggaagcttct tagcttcttg
      301 cttaggtgct ggtttcttct cttccttctt agcttcaggt tttggagccg gtttaggttg
      361 aggttttggc tctggcttag gctcaggttt tggttctggc ttaggctcag gttttggctc
      421 tggcttaggc tcaggttttg gttctggctt aggctcaggt tttggttctg gcttaggctc
      481 aggttttggt tctggcttag gctcaggttt tggctctggc ttaggctcag gtttaacctc
      541 ttcatacaca taaaccacac gaagatcgcc ttctagggtt gtaccagttt cgctaggtga
      601 gccctcttga agcttcttga acttgtagac cttaccatct ttttcaatct tatcaagacg
      661 aagtgaggta gtatcgtacg cttcacccgg taagccttgt gataccgcaa cagtctcacc
      721 taaaacatta ccttctgtat ccacataaga tacaagaacg ttagcattaa acggaacaaa
      781 ttcccaatca ccaattaaag taatatctcc atcacctggt gctgtatagc cctctgtaag
      841 tttagtttca ccatcatttg tgtaacgtga ccaaccagta aatctccact caccagttgc
      901 agttctgaca ttaccaaaag ttggcaatgg aaccttttca cccttcttaa ccactacaga
      961 ttctggcatt ttagcagcat caagaagctc ctgtggtaag gtcatacctt gcttgctacc
     1021 gaaaatgtag ataactgtac tcttttcttt acgaagagct tcgttagctg cttcttccca
     1081 agcattttgc aatctctctt cttctgcttt ctgtcttgct gcttccgctt ctgcttctgc
     1141 ttttgctgcc tcttcgacag ctttcatttt aatctcttca accttagcct tcatttcatc
     1201 tagactatac attccttgaa ggctggcctc aatatccgta ttagccattg gatattgttt
     1261 tttaaactct tcaagttcct tttttagctc agttataact ttctgctttt cgcctcttgt
     1321 aaatggttgt gccgatacag aagctgtacc aactaacaag gctgcagata ctgaagctag
     1381 tccgaaagcc gacttacgaa gatagtactt catttctttt tttgccattt ttattcccct
     1441 ttaaatataa tggacataat gtctcctaat tatcaatgac agataattat acttttatta
     1501 taaaaggtat tttctgttta gtcaagatta aactgtttct tgtacatttc tgttatttta
     1561 cagttatatg tcacatctga tttgattta
//
LOCUS       DARYSY010000134         1539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYSY010000134 DARYSY010000000
VERSION     DARYSY010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            175..1197
                     /locus_tag="TVR04_001984"
     CDS             175..1197
                     /locus_tag="TVR04_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270639.1"
                     /translation="MFKKKTFITTIGLLTSLTLMSACSNTTKPSPTTSHSPEKTSSEK
                     TKEISIGNYINQSKKAPQLWYEIDGEEVIKGVYVFEDNQVIYYDTSYEKTTNTETTIS
                     SAQFKADYVGKNVYSTGQHAQGFFDSFYGTDTAEKISEEMLTDIIKKYDTEDGNADGI
                     IDITIPDTLTLQSISTLSDDEIIEQAKAFEKASTHKQIIFEKVSLALRQLVDGKDTTP
                     TIDKLTETENQYIQKIASDYQLKILPDEDLLETLEETLKIPIQKIIYDDVINYSYIIK
                     EDSFTAYLTDSQFASNSINNVKYIGFPTFVTKQKEGDNVTLIYDTYDLRPDNVQVTSD
                     SADNEE"
     gene            1213..>1539
                     /locus_tag="TVR04_001985"
     CDS             1213..>1539
                     /locus_tag="TVR04_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEL1270640.1"
                     /translation="MKKIKALLLTLTAVLLLTACSASNQSLDGTYTYEEDGSRMTIII
                     DGQDGSLSIEAGNGNGSLFGEDSISTDFSLDKESNTFNVEGEELDYSLSGNTLTVSGD
                     GFGTVKL"
BASE COUNT          576 a          253 c          251 g          459 t
ORIGIN      
        1 agtgaaatat attcttgtaa ttggtcgtgt ttcatgtttc acctctttcg tttattctac
       61 tatccatttt ctccaactat aagtacaaca aacaatctaa aatcacacga aagtgttgcg
      121 tattgtctgt tttgttgata caatagataa ataaccatac aaaaggagaa ttttatgttc
      181 aaaaagaaaa cttttatcac tacaattgga cttttaacct ctttaacttt gatgagtgcc
      241 tgttcaaata ccaccaaacc ttccccaact acttctcact ctccagagaa aacttcttct
      301 gaaaaaacaa aagaaatcag tatcggaaac tatataaatc aatctaaaaa agctccccag
      361 ctctggtatg aaatagatgg tgaggaagtt atcaagggag tatatgtttt tgaagataat
      421 caagtaattt attatgatac ttcttatgaa aaaactacaa acaccgaaac aacaatttct
      481 tctgcacaat ttaaagcgga ctatgttgga aaaaacgttt attcgactgg tcaacatgcc
      541 caaggcttct ttgatagttt ctacggaaca gacacagcgg aaaaaatttc tgaagaaatg
      601 ctaacggata ttatcaaaaa atatgatact gaagacggta atgcagatgg aatcatcgat
      661 attacaattc cagatactct tactcttcaa agcatttcaa cattatcaga tgatgaaatt
      721 attgaacagg ctaaggcatt tgaaaaggct agtacccata aacaaattat ttttgaaaaa
      781 gtatcacttg cacttagaca attggttgat ggaaaagata cgactccaac aatagacaaa
      841 ttgacagaaa ctgaaaatca atatattcaa aaaatagcgt cagactatca attaaaaatt
      901 ctaccagatg aagacttgtt agaaacttta gaagaaactc taaaaatccc tattcaaaaa
      961 atcatctatg atgatgttat taattatagt tatattatca aagaagattc tttcactgca
     1021 tatctgactg actctcaatt cgcttcaaac tcaataaata atgtgaagta tattggtttc
     1081 ccaacatttg tcacaaagca aaaagaaggc gacaatgtca ctttaattta tgatacttac
     1141 gatttgagac ctgacaatgt tcaagtaact tcagatagcg ctgacaatga agaataaggg
     1201 aaggagaaaa tgatgaagaa aattaaagca cttttactaa cactcacagc tgtactgtta
     1261 cttactgcat gttctgctag taaccaaagt ttggatggaa catatactta cgaagaagat
     1321 ggaagtcgca tgacaatcat aattgatggg caagatggct cacttagcat tgaagctggt
     1381 aacggtaacg gttcgctatt tggagaagac agtattagta ctgactttag tttagataaa
     1441 gaaagcaata catttaacgt agaaggagaa gaattagact attctctttc aggaaatact
     1501 ttaactgtta gtggagatgg ttttggaact gttaaattg
//
LOCUS       DARYSY010000135         1509 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYSY010000135 DARYSY010000000
VERSION     DARYSY010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..366
                     /locus_tag="TVR04_001986"
     CDS             <1..366
                     /locus_tag="TVR04_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270641.1"
                     /translation="EQGPQGERGEQGPQGERGEQGPRGENPTPNPDPMPQPKPQPMPD
                     PAPKPMDPQPESKPEPKPTPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFG
                     TGLLSLLGLGFLAKRKRKQ"
     gene            660..>1509
                     /locus_tag="TVR04_001987"
     CDS             660..>1509
                     /locus_tag="TVR04_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1270642.1"
                     /translation="MRKTAKKMLAASTICIIMSGSFIGGAARVLADQQQYYGWNDGTR
                     YASPLFLYVTPTNESQRKPENSNVVYCFNRDKEWPENWESVYPTPESIPYPYKLPLYN
                     KLTGTTETFKQNASNPRQIGDIGKALVAVLANGYPNKQLSHDNTKSRILTQLAIWYFS
                     DSFDKQYFKDNYHLTEEENKSLMDLIETGEKAAKGHEQPTYHLDIYVTTQQSYDRHKP
                     FQNLLGSTLVPLPKPGPKPEPMPDPEPKPEPKPEPMPKPEPKPEPKPEPKPEPKPEPM
                     PDPEPKP"
BASE COUNT          565 a          349 c          262 g          333 t
ORIGIN      
        1 gagcaaggac ctcaaggcga acgcggtgag caagggcctc aaggcgaacg cggtgagcag
       61 ggacctcgtg gggaaaatcc tactcctaac ccagacccaa tgccacaacc aaaacctcag
      121 ccaatgcctg atccggcacc taaaccaatg gatcctcaac cagaatccaa gcctgaacct
      181 aaaccgacac ctcaaccaga gacaaaacct caacaaccaa acaagccatc aaccattact
      241 agccaatcta gcggcaaatc actgccaaaa acaaatgaca caggcagcct gatcacagca
      301 tttggtacag gcttactctc tcttcttgga ctaggcttcc tagcaaaacg caaaagaaag
      361 caataaacaa ctaacacaca atcattagta atccattcat tatccattta caagttatca
      421 taaaaaaaag ccttatcaca ccagtcaagg aatgataagg ctttttgctt accttaatac
      481 agtatttgtc aatctgtaac aatatcagat aatttcaatt tgtattaaaa aaaaaaaaac
      541 gaaactacgg aagctaattg tcagaaaact attcacaacc tacttccatc atgttaagct
      601 attctgcgga aaagaaagat ttaggaagga ttattctaaa ctcaaaggag agagaaacaa
      661 tgagaaaaac agctaagaag atgctggcag cctcgacaat ctgtatcatc atgtcgggca
      721 gctttatcgg aggcgcggca agagtactgg cagatcaaca acagtattac gggtggaatg
      781 atggaactag gtatgcatcg ccactttttc tgtatgtaac accaacaaat gaaagtcaga
      841 gaaaaccaga aaacagtaat gtggtctatt gctttaacag agataaagaa tggccagaga
      901 actgggaaag tgtatatcct actcctgaat ctataccata cccatacaaa ctacctttat
      961 ataataaatt aactggaaca actgaaactt ttaaacaaaa cgctagtaac cccagacaaa
     1021 ttggagatat tggtaaggct ctagtagcag ttcttgctaa cggttatccc aataagcaat
     1081 tgagtcatga taatactaaa agtagaatat taacccagct agctatctgg tatttcagcg
     1141 atagtttcga caagcaatac tttaaagaca attatcacct aactgaagaa gaaaataaat
     1201 ctcttatgga tttaattgaa actggagaga aagcagctaa aggacatgaa cagccaacat
     1261 atcatttaga tatttatgta acaacacaac aaagttacga caggcataag ccatttcaaa
     1321 atcttcttgg ttcaacttta gtacctcttc cgaaacctgg ccctaagcct gaaccaatgc
     1381 ctgatccgga acctaaacca gagcctaagc ctgaaccaat gcctaaacca gagcctaaac
     1441 cagagcctaa accagagcct aaacctgaac ctaagcctga accaatgcct gatccggaac
     1501 ctaaaccag
//
LOCUS       DARYSY010000136         1499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYSY010000136 DARYSY010000000
VERSION     DARYSY010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1499
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            70..1464
                     /locus_tag="TVR04_001988"
     CDS             70..1464
                     /locus_tag="TVR04_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1270643.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENITYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGKLIQMDASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEAHGVPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITISQANRYLKRWIKRFNKQFGGLASESVFEKAPKP
                     AQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKEIYFTRKTKALVIEAFDGDIYLN
                     IADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKSY
                     EEFKRERNTSQPQL"
BASE COUNT          530 a          299 c          296 g          374 t
ORIGIN      
        1 tcttagctag gtcgaatgtg aaaatgtccc gtctgttaaa ctagaaagat gaggaaaata
       61 gaactaacta tgatagagtc aaagaaatac ctagtcatca aagctgtttg tgagggtaaa
      121 aaacagaaaa acagggcttg tgtagaatta gggttaagca agaggcaggt gaaccgattg
      181 atactagcct atcgagagaa aggaaagtca gctttcgttc atggtaatag atcaaaaaga
      241 ccaactcatg ccatgtcttt agaaacaaag agaaggatta tcgagaaata tcaaagttac
      301 ggtgatttaa gaccaaatgt tgttcatttc tgcgaactac tagcggaaga agaaaacatc
      361 acctattcag atacaactgt tagaaaacta ctctaccaag cagggtttct atctccaaag
      421 actcaacgag caacgaaaag acgattgaaa caagaagcca aacaaaagaa aagggaggca
      481 gaaaaaagag gatccaaact cccaactgct tccaacttct ttgaagaacc tgacaaagct
      541 catcccagcc gagcaagaaa gaaattcaaa gggaaactca ttcaaatgga tgccagtcaa
      601 ttcccttggt ttggacaaca ggaaacacat cttcatgtcg ctattgacga tgcctccggt
      661 gatattgtcg gggcttactt tgatactcag gagacgctaa acgggtatta tcatgtctta
      721 gaacagattc tagaggcaca tggtgtccct ttccagttcc ttactgataa aaggactgta
      781 ttcacttatg cttccagtca gtctaaaaag atcgaggaag atacctttac acagtttgga
      841 tatgcttgcc atcagcttgg tattgccatt gaaacgtctt ctatccctca agctaaaggg
      901 cgtgtagaac gtcttaatca gacccttcaa tcgcgtctac caattgattt acagaggaat
      961 caaattacca tctctcaagc gaatcgttat cttaagagat ggattaaacg atttaacaag
     1021 cagtttggtg gactggctag tgagtctgtt tttgagaaag cacctaaacc agcccagcga
     1081 aacctactgt tagcgagaat ctctgaaaga gtaattgata gtgggcatca tattcgatat
     1141 caaaacaact tctacttgcc cgtcgaaggg gataaagaaa tctattttac gcgtaagaca
     1201 aaggcacttg tgattgaggc attcgatgga gacatctacc ttaatatcgc agacaatatt
     1261 tatgccacta gaaagttacc aaaacacgag aagcactcca aagaattcga aatggtgcct
     1321 aaaactaaaa aagaaagacg caagtatatt ccaccacaat cccatccgtg gaaacttgca
     1381 tctttcaaac aataccttca taaaatcgga aaatcttatg aagaattcaa gcgtgagagg
     1441 aatacctctc aaccacaatt ataacagatg tttctcttat ctaaccgatt ttttcaaga
//
LOCUS       DARYSY010000137         1490 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYSY010000137 DARYSY010000000
VERSION     DARYSY010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1490
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            37..1161
                     /locus_tag="TVR04_001989"
     CDS             37..1161
                     /locus_tag="TVR04_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679400.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1270644.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKAELTAAEAAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQETQEKLNRENTPSPERIVSDDEDDTVARKLMSEKEALKAELQKTKES
                     LEVAKKAYAGIEERKQVAAVKLDAANKAFAGVEEKHAQAMAKFAEAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSANTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDANKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1323..>1490)
                     /locus_tag="TVR04_001990"
     CDS             complement(1323..>1490)
                     /locus_tag="TVR04_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="HEL1270645.1"
                     /translation="LMNCAESQDYPEVTQKYVFELYIASIEVIIIKWISCGCKDSPQQ
                     IIEILKLLRSK"
BASE COUNT          524 a          316 c          337 g          313 t
ORIGIN      
        1 gacatcatgt ctagataaaa acaaaagggg aataaaatgg caaaaaaaga aatgaagttt
       61 taccttcgta aatcagcctt tgggctagct tcagtatcgg cagccttgtt ggttggtgcg
      121 gcagctgtat cagcagattc tgttgagtca gctgggcctg tagcagttgc tgttacagat
      181 agtttagata gtgaagccgc agctacaaag gcagaagctg atctagttgc tgcaaaagca
      241 gagctaacag cagcagaagc agcaatcaca gctgcaaaag ctgaatttga caccgctcaa
      301 gcagacctag ctaccgctga agctactatc gcagagcttg agcaaaaaat tcctgagtta
      361 gagaaaaaga ttcaagaaac tcaggaaaag ttaaatcgtg aaaatacgcc gtcacctgaa
      421 cgtatagtaa gtgatgacga agatgataca gtagctagaa agcttatgtc agaaaaggaa
      481 gctcttaagg ctgagcttca aaagactaaa gaaagtctag aagtagctaa aaaagcttat
      541 gctggtatcg aagaaagaaa acaagtagca gccgttaagc tagatgcagc taacaaggcc
      601 tttgctggag ttgaagaaaa gcatgctcaa gcaatggcta aatttgcaga agcatttgca
      661 gcatacaagg aagctgtcaa ggctgaattg aaggcagcag gtgctagcga cttctacacc
      721 aagaagattg actctgccaa cacagttgac ggtgttaaga cactcagaga aatgatctta
      781 gactcaattg ctaagccaga ggttgaacca gaggctaagc ctgaacctaa gccagaacca
      841 aaacctgagc caaaaccaga acctaaacca gaacctaagc cagagccaaa accagaacct
      901 aagccagagc caaaaccaga acctaagcct gagcctaagc cagaaccaaa accagaacct
      961 aagccaaaac ctcaacctaa accagctcca gctccaaaac ctgaagctaa gaaggaagag
     1021 aagaaagcag cgcctaagca agacgccaac aaattgccat caacaggtga agctacaaat
     1081 ccattcttca ccgcggcagc tcttgcagtt atggcaggtg caggcgtggc tgcagtgtca
     1141 acaagacgca aagaaaacta agccttatac cccagtggta aagcttgagc gagaacaatt
     1201 tgttctcgct tttttagtgt cttaaaagca cctatgcttg ctataggtgc ttgaaaagat
     1261 ctgtctaacg attgctatca gctgtagaga ataaaaagga gagactaagc cttgctcaca
     1321 agctacttag accgaaggag ctttaggatt tctatgattt gctgagggga gtccttacag
     1381 ccgcagctga tccacttaat gatgataacc tcaatagagg caatgtatag ctcaaaaaca
     1441 tatttttggg taacttcagg ataatcttgt gattctgcac aattcatgag
//
LOCUS       DARYSY010000138         1415 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYSY010000138 DARYSY010000000
VERSION     DARYSY010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            358..>1415
                     /locus_tag="TVR04_001991"
     CDS             358..>1415
                     /locus_tag="TVR04_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEL1270646.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     KKQGVISKEIFLPDHAPKEYKDRKTLWNSVELFEKNSNAQLARNFIISLPKELSIEEN
                     KKMIEEYIQTNFVKEGMIVDLAIHDESREGNQNIHAHIMTIVRPINEDGTWGQKSKKE
                     YILDEQGEKILNKNGKPKTRKVELTTWNDKGNVEKWRENFSKLCNEYLAKNKIEKRVD
                     HRSFKRQGIKQIPTIHLGASASAMERKGIRTEKGDINREIKKQNELLKNIGNEIKKIT
                     SWLIGFKDKLKESYKEYKDQSKKQIENESGLFNLYEYLSFYQEMQENSRAELSFYGKR
                     NKAIYDLKRYASGINYLR"
BASE COUNT          657 a          202 c          245 g          311 t
ORIGIN      
        1 cattcaattc aagacaaata aatgagaagt aaataaacaa atctccctta gattttctaa
       61 gggcgcaatt atacacccta aagggtgctt gcgtgccttt ggagccaaac ccttgcaggg
      121 agcaacaacc attcgctttt taaaagtcaa gggtaaataa actcgctaag gctcgccctt
      181 gacttttaaa atttgaaatg aacaaaacaa ttaagccgac atactgaaac aacaaaaatt
      241 aattcagtag tcggcttttt ctattctatc atttcaaaac gctaattcac aaagtggcta
      301 taaaaaatct attaagcctc cacctaaaac aacaaagaaa gaaaggaagt gataaaaatg
      361 gcagacagtt ttcatttttc agtaaacata atatcaagag gaaaaggcaa aagtgcagta
      421 gcaagtgcag catatataag tggagaaaaa ataaaaaatg aatgggacgg agtaacccat
      481 gactacacca aaaaacaagg agtaattagc aaagaaatat ttttgccaga tcacgcacca
      541 aaagaatata aagaccgaaa aaccttgtgg aactcggtag aactatttga gaaaaactct
      601 aatgcccaac ttgcaagaaa ctttatcata tctttaccaa aagaattaag catagaagaa
      661 aataaaaaga tgatagaaga atatatacaa accaactttg taaaagaggg aatgatagta
      721 gacctagcaa ttcatgatga aagtagagag ggcaatcaaa atattcatgc tcatataatg
      781 accatagtaa gaccaataaa tgaagatgga acatgggggc aaaaaagtaa aaaagaatat
      841 atcctagatg aacaaggaga aaagatttta aacaaaaatg gaaaacctaa gacaagaaaa
      901 gtagaactaa caacatggaa cgataaaggc aatgtagaaa aatggagaga aaatttttca
      961 aaactttgta atgaatatct agcaaaaaac aagatagaaa aaagagtaga ccataggagt
     1021 tttaaaagac agggcataaa acaaatacca acaatacatc taggagcaag tgctagtgca
     1081 atggaaagaa aaggaataag aacagaaaaa ggagatataa atcgtgaaat aaaaaaacag
     1141 aatgaactat taaaaaacat aggcaatgaa ataaagaaaa taacatcatg gttaataggc
     1201 tttaaagata agctaaaaga atcatacaag gaatataaag accaaagtaa aaagcaaatc
     1261 gaaaatgaat caggactctt taacctctat gaatatttaa gtttctatca agaaatgcaa
     1321 gaaaatagta gagctgaatt atcattttat ggtaaaagaa acaaagcaat ctatgatctc
     1381 aaaagatatg caagtggaat aaattatcta agaga
//
LOCUS       DARYSY010000139         1401 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYSY010000139 DARYSY010000000
VERSION     DARYSY010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1401
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(14..85)
                     /locus_tag="TVR04_001992"
     CDS             complement(14..85)
                     /locus_tag="TVR04_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEL1270647.1"
                     /translation="MKKISKLVPILVLVMDIIIIVGG"
     gene            167..1018
                     /locus_tag="TVR04_001993"
     CDS             167..1018
                     /locus_tag="TVR04_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1270648.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLEEFLILHNEDYTNGESFANLVQYIRKQYSSQSINNIACLLYDT
                     SNYTLNSLEKTMVKSILHTMDSNVIPSDEELLQLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCLILSIDKEKFSNCSYLIDEIK
                     ALLDNELNFYEQTVFLYATGYFEFKRQSGTGIEKMKQAIQVLDILGEDKLKLHYTDHF
                     DKLVNKE"
BASE COUNT          492 a          245 c          197 g          467 t
ORIGIN      
        1 acacctaagc gatttaccca ccaacgatga taatgatgtc cattaccaat accaaaattg
       61 ggacaagttt tgaaattttc ttcatactca gacttccttt cagtttttat ttattgtaca
      121 ataaataaaa actgagttaa tttttgttgg gaaaatggga aaaattatga aatcaaaact
      181 tggcatcaca cttagaaaag ttcgtaaagg aaaacaaatt agtctatgct ctgtagcaga
      241 tgaacatctt tcaaaatcac aaatatctcg ttttgaacgt ggagagtcag agatatcttg
      301 tattcgacta atcaatattt tggacaaatt acatattact ttggaggagt tccttatttt
      361 acataatgaa gactatacca atggcgaatc atttgctaac ctggtacagt acattcgtaa
      421 gcaatattca tcacaaagta tcaataatat agcatgtcta ctttacgaca cttctaatta
      481 cactttaaat tctttggaga aaacgatggt aaaatccatt ttacacacaa tggattcgaa
      541 cgtcattcca tcagatgaag agttacttca actgaccgac tatcttttca aagtcgaaaa
      601 atggggctac tatgaaatca ttttattagg taactgtgta cgtacaatta actacaactc
      661 ctacttctta ttaaccaaag aaatgttaaa caattacatt tactcatctc tgaataaaac
      721 caataagcgt attgtcactc agctcgctat caattgctta attcttagca tcgataagga
      781 aaaattttct aattgctcct atttaattga tgagataaag gcgttgttag ataatgaatt
      841 aaacttttat gaacagacag tttttctata tgcaactggt tactttgaat ttaagcgcca
      901 atcaggcact ggaattgaaa agatgaaaca agccatacaa gtacttgata ttttaggaga
      961 agacaagtta aaattacact atactgacca tttcgataaa ctagtcaaca aagaataagt
     1021 gaaatgttat tctaaaattt aacgacatat cgatcaaggg tgtctcaata aaaaatccct
     1081 gctctagcaa cttttccctt gtacccatag acagttaaaa agccttggaa tatgctgttt
     1141 ccaaggcttt ctttgcactc tattgtatca atttccttat tccgatttct gtcgcaatta
     1201 gttttatcat acaatatcac cttttttcat ctttaggggg tgcaaattta gcatctgctt
     1261 tcttaagtta cattataaca cattaaaaat ataaaaattg caccaagatt ggtacgattt
     1321 aaacttcatt tttgtcctaa attttctatg ttaacatagt aagtctgtaa cttaatacat
     1381 cgctatttct ccagataaaa a
//
LOCUS       DARYSY010000140         1383 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYSY010000140 DARYSY010000000
VERSION     DARYSY010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(14..1189)
                     /locus_tag="TVR04_001994"
     CDS             complement(14..1189)
                     /locus_tag="TVR04_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002839467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEL1270649.1"
                     /translation="MFYIGVDIAKKNHEASIIDSDGKLVSESFSFSNSIRGLEKFQKF
                     ISSFSIDSNNCIIGMEATGHYWLSLYSFLIDLGFSCIVINPIQSDAFRKMYIRQTKND
                     SVDSFVIAQILRFGEFSVSHFSDEDTFALRNLSRFRFALVDEASDWKRKLVCILDQVF
                     PEYSSLFSNIYGVASKELLSKYPLPEDMISIPADELAKMLSKCSKGRFGIDKAKEIQE
                     KASNSFGVKFALKSFSFQIKQIIAQISFLEDQIADIEDEISSMINSLCPVITSITGIG
                     DVLGAAIFSEIGDISRFERANQLVAYAGLDVAVKQSGNFNATDTKISKRGSPYLRRAI
                     WLAASVAAFKDPALSVYYQKLRQRGKAHGTAIGAVARKLTNIIFAVLRDNKAYIPNI"
BASE COUNT          575 a          272 c          200 g          336 t
ORIGIN      
        1 aactaaataa caattaaata ttaggtatgt aagctttgtt atccctcaaa acagcaaaaa
       61 taatgttagt aagttttcta gcaactgcac caatagctgt accatgagct ttaccccttt
      121 gtctaagttt ttgataatac acagacagag caggatcttt aaaggcagca acactagcag
      181 caagccaaat agcacgtcta agataaggag aaccacgttt agaaatctta gtatcagtag
      241 cattaaaatt gccagattgc ttaacagcaa catctaaacc agcataagca accaactgat
      301 tagctctctc aaaacgagaa atatcaccaa tttctgagaa aatagcagca cctaagacat
      361 caccaatacc ggtgatagaa gtaataacag ggcataaaga attaatcata gaagaaattt
      421 catcttcaat atcagctatc tgatcttcaa gaaaagaaat ttgagcaata atctgtttaa
      481 tttgaaaaga aaaagacttt aaagcaaact taacaccaaa agaattagaa gccttctctt
      541 gaatttcttt agccttatca ataccaaagc gacccttact acacttagac aacatcttag
      601 caagctcatc agcaggaata gaaatcatat cctcaggcaa aggatactta ctcaaaagct
      661 ccttagaagc cacaccataa atattagaaa aaagcgaaga atactcaggg aaaacctgat
      721 ctaaaataca aacaagcttt ctcttccaat cagaagcttc atcaacaaga gcaaacctga
      781 acctagaaag atttcttaaa gcaaaagtat cctcatcaga aaaatgagaa acagaaaact
      841 caccgaacct aagaatttga gcaataacaa aagaatcaac agaatcattc ttagtctgtc
      901 taatatacat ctttctaaaa gcatcagatt gaatagggtt aataacaata caagaaaaac
      961 ctaaatcaat taagaaagaa taaagcgaaa gccaataatg gccagtagct tccataccaa
     1021 taatacagtt gttagaatca atcgaaaaag aggaaataaa tttctgaaac ttctctaaac
     1081 ccctaataga attagaaaaa gaaaaggact cagaaacaag tttcccatca gaatcaatta
     1141 ttgaggcttc gtggtttttc tttgcaatat caacaccaat gtaaaacata aaatcaccta
     1201 gctttaatat aaatttagat agagaaagga ccctcaagaa ctttacgaca atcaaacctc
     1261 gttagacata cagcaacgaa atgcgctatc cagctcatac tgataaagac gtaaagaaga
     1321 ggcgtaaccc taatttagga agactagctt caaggaggtt aactacgacc tctatctata
     1381 caa
//
LOCUS       DARYSY010000141         1382 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYSY010000141 DARYSY010000000
VERSION     DARYSY010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            2..1382
                     /locus_tag="TVR04_001995"
                     /pseudo
     CDS             2..1382
                     /locus_tag="TVR04_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611955.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          498 a          238 c          291 g          355 t
ORIGIN      
        1 tatgtccaag agaagcccaa aatcagtaga agaaaagtta gagcttgtac agctgtatca
       61 agaacaagga gtatctattt caaccttagt tagttcttat ggagtggcta gtacaactat
      121 caagaagtgg attagaaaat acgaaaactc aggcatagat ggtcttaaag aaagtcgaac
      181 ttggaaacaa tacagtaaag aattgaagga acaagctgta caagactatt taaacaactt
      241 aggaagttta gagacgatta ttgagaaata tcatatttct agtcaaagtg ttctcaaacg
      301 ttggataaac cagtatacta gtgataaagc attacaaacc actagtaaag gactaagtcg
      361 tatgaagcaa ggacgaaaaa ccacttttga agaacgtgtt gagattgtca acttcaccat
      421 tgctcatgat aaggactatc aagcagctat tgaaaaatac ggtatttctt accaacaagt
      481 ttattcatgg gtaagaaagt ttgagaagga cggtagccaa ggacttctag accgcagagg
      541 gaaagggtta gaaagtaagc ttaaccttac tccggaagaa gagttacagc ttaaaatcaa
      601 acagttagag gaacgcaatc gttaccttga aatggaggta ggattgctaa aaaagttaga
      661 agaaatcaga cgcagaaacc gacggtaaga atcggacgtt acttagaaga atttcaagct
      721 attaaagatt attccgataa gcatagtgaa gcttctatta gccagttatg ccaattgatt
      781 ggtgtatctc gatcaggtta ttataagtgg cttaatcaca aagagacgac atctgaggag
      841 acaaatcgaa cactattaaa aaccataaag gaacttcata ccaaacgcaa gggaatttta
      901 gggtatcgtc gaatgacgcg agctgtcaat cggaaacttg gaacaactta taacaagaag
      961 cgaattcgtc gcctaatgcg cattcttggt atctcctcaa ttatccgtcg ttctcgtggt
     1021 tattgcacga aaaccagttt tgtgaatatc gaagagaaca ttctcaatag agaatttgca
     1081 gctcatgccc ctaatcaaaa atggtgtaca gatgtgactt tcttacagta tggacgaggt
     1141 tgtaaggctt atttaagtgc tattaaagac ctttatgacg gctctatcgt agcttaccat
     1201 atcagtaagc acaatgataa tccacttgtt atggaaactc taagaaaggc aatagagatt
     1261 aactcaggag ccacaccatt gcttcatagt gatagaggct cccaatacac gtcgcgggaa
     1321 tatcgcatgg taacaacaca gtatcagatg acacgttcaa tgtcacgagt tggtaaatgc
     1381 at
//
LOCUS       DARYSY010000142         1362 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYSY010000142 DARYSY010000000
VERSION     DARYSY010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            53..640
                     /locus_tag="TVR04_001996"
     CDS             53..640
                     /locus_tag="TVR04_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270650.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNDFPEDSISLSFADNKFV
                     IEEIHRDNRIRLMETTSEDNAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            1076..>1362
                     /locus_tag="TVR04_001997"
     CDS             1076..>1362
                     /locus_tag="TVR04_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1270651.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYHKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLS"
BASE COUNT          491 a          189 c          283 g          399 t
ORIGIN      
        1 atgggttttt tagatgacat aactgatttg gtgaagaaag gggaaattag gattgattga
       61 taaaataaaa aacattcttt ttgatgttag actgagtgca aataaaatag aaaatgaaat
      121 aatattttat aatgattttc ctgaagatag tatatcttta tcatttgcgg ataataaatt
      181 tgttattgaa gaaattcatc gagacaatag aatcaggtta atggaaacaa cttcagaaga
      241 taatgctatt ttatattgtg ttgcaatttt ggaccagatc tttaatacta gtaaaaatat
      301 caagattaca agagaaatca aagagtatat acaggaagga aatattatag cagctgagca
      361 gttgctctca gaaaaattgg atcctactct tttttcatta gggtctgtgg aaaaagataa
      421 attaaccctt gtaaaagaaa ataatgccta tagtttaata tttaatgatg tgcaaattct
      481 aactgattta agttcattac gtgcttacat tgttttattt aattacacta aaaaacttga
      541 gagagcaaaa gaattatatg ctagagcact acatgacttg cctgattgta aattagaatt
      601 taatcagttt gtagagtatt atctgatagg aaggaattaa taaaagaact attgaaatac
      661 catatggcat tttgagttca gatgcccagt catggcagga ggcagcgaaa cagacgtcca
      721 gcgagctaca ttggtaggga atatcctagg aggattcgcc gcctcaagcg tcgccagaag
      781 gttcagcttg aatgagccaa tagcagctag ggtgatgaaa ccgacctaca gccgccggca
      841 gcttttgaag aaccttgaga acagcaggct ggcaagagag agcttgaggt ttgatgatta
      901 tcttcgaaga gaataccggt taaagggaag gtattttgca gaaagaacca ctatttcaaa
      961 tggaaagata ggttatcttt catctgacta ttttgaaggc aagcaaattc cggttcgctc
     1021 tagagctttt gttaacgaag caggacatat taaatggcca aatgccgatg gctttatggt
     1081 ggataattta ggtaatccta taacggagca ggtcactctc aaagcaggtc aaatcattga
     1141 tcgatatgga tcaagtagtg gtcgatttac cagtccgata gaaaatgggg tgacattacc
     1201 atttaataaa cgtggattac cctacccaga aggatatcaa gactatcata agtacgaatt
     1261 agtaatggat ttgacgaaga aaaatattgt taatgcgtat tatcaatctg aagagattat
     1321 aagaaaacaa atatctgtag aaatgaaaaa atggaatctt tc
//
LOCUS       DARYSY010000143         1352 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYSY010000143 DARYSY010000000
VERSION     DARYSY010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            133..1215
                     /locus_tag="TVR04_001998"
     CDS             133..1215
                     /locus_tag="TVR04_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HEL1270652.1"
                     /translation="MSKEMDKNKDQNNDKKELQIRSSAAEYLTFIAANGDDQEAIEIR
                     YEDENIWLTQKMMATLYDVSTAAINQHLKKIFDDNELQEEATIKNFLIVQKEGSRNVS
                     RETKHYNLQAIIAVGFKVNNERAVQFRKWANQIVKDFTIKGWAMDDERLKNSGTKLTK
                     DYFEKLLVKIREIRLSERRFYQKITDIYATSLDYDPSAKATKRFFAAIQNKLHYAIHG
                     KTAAELIVDRANHKTKNMGLTTWEGSPDSKIHKYDVVVAKNYLNEEELNQMQRIVSSY
                     LDMAELQAERHIPMTMEDWEKRLNGFLQLWDKEILSDAEKVSAALAKKHAESEFEKYR
                     IIQDRLYKSDFDKFLELEDNTKDLEK"
BASE COUNT          551 a          184 c          227 g          390 t
ORIGIN      
        1 taggtcaaac ttatcatcaa ttaccaataa ccaaaagtat gatgataaat tcctttatac
       61 attatgtaat tgtattcttg attagtattc cagtttttaa aggtagaatg aaatttatac
      121 ttggaggaat ttatgagtaa agaaatggat aaaaataaag accaaaataa tgataaaaaa
      181 gaacttcaaa tcagatcttc cgctgccgaa tacttgactt ttattgcagc taatggtgat
      241 gatcaagaag ctattgaaat tagatatgaa gatgaaaata tttggctaac tcaaaagatg
      301 atggcaacac tttatgatgt cagtactgca gcaataaatc agcacttaaa aaaaatattt
      361 gatgacaatg aattgcaaga agaagcaact attaagaatt tcttaatagt tcaaaaagaa
      421 ggttctagaa atgtttcaag ggaaacaaag cactataatc tgcaagcaat tattgcagta
      481 gggtttaaag taaataacga acgtgccgtc caatttagaa agtgggcaaa ccaaattgta
      541 aaagatttta caattaaagg ttgggcaatg gatgatgaaa gactcaaaaa ttctggcaca
      601 aaacttacca aggattattt cgaaaaatta cttgtaaaaa ttcgtgagat tcgattatct
      661 gaaagaagat tctatcaaaa aatcacagat atttatgcca cttctttaga ctatgatcca
      721 tctgcaaaag caacaaaaag attttttgcc gctattcaaa acaaattaca ctatgccatt
      781 catggaaaaa ctgcagctga attaattgta gatagagcca atcacaaaac taaaaatatg
      841 ggacttacta cttgggaagg atctccagat tcaaaaattc ataaatatga tgtagtcgtt
      901 gcaaaaaatt atctaaacga agaagaatta aatcaaatgc aaagaattgt ttcatcatat
      961 ttggacatgg cagaactaca agcagaaaga catatcccta tgactatgga agattgggaa
     1021 aaaagattaa atggattttt acaactatgg gataaagaaa tcttaagcga tgcagaaaaa
     1081 gtatctgcag cacttgctaa aaagcacgca gagagtgaat ttgaaaaata cagaattata
     1141 caagacagac tctacaaaag tgattttgat aagttcttag agcttgaaga taatactaaa
     1201 gatttagaaa aataacttaa tatacgatta acgcttataa ggggcggaaa tgtaaataat
     1261 tttgtgtatc aacctaaatc ctgattaaaa ggtaagggtt gatacatttt ttattcttaa
     1321 tcttcatttg tgtggctaca acttattcta ca
//
LOCUS       DARYSY010000144         1341 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYSY010000144 DARYSY010000000
VERSION     DARYSY010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..630)
                     /locus_tag="TVR04_001999"
     CDS             complement(<1..630)
                     /locus_tag="TVR04_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1270653.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSR"
     gene            complement(1038..1268)
                     /locus_tag="TVR04_002000"
                     /pseudo
     CDS             complement(1038..1268)
                     /locus_tag="TVR04_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          376 a          272 c          173 g          520 t
ORIGIN      
        1 tctgctatag gatatattta tggagtaaag acttaaaatt gctccagtaa aaacattatt
       61 tggaacattg gaaggtaata cataaaatgc aggtatatag gttgctaaaa cccctgacat
      121 aacaattcct tcccattcct tacttccttt ttcataacct aattctaaag atagggcatt
      181 tagaataggt aaaagcaaaa ctactctacc cattgctgat ggcatcaaaa aaattagtac
      241 cactcctagc aaaatcgtcc caaataacac tttagaatat ttccccatgc acaccggaat
      301 aaaaaatctc gcaagtaatc tatcaagttc agtatgcttt actgccgccc ctataataac
      361 acctgaaata acaagccatg ctgcacctga agttatccct gataagatga cttgcttctc
      421 agctatattc cctatcatac aagctgtcat aaataaaatg cttgtatacc atgcaggaat
      481 tatattgctt gccaaaagga agatagatat aagaatcaaa ataaaaactt tctctatatt
      541 tgaaataaat ggtagtacag atacaaacaa cggtaacatt gtaaatatcc actttatatg
      601 attattccta attccagatt ttaaaatcat cctccatttt tgacctccaa ctctaattta
      661 tttcatagta ttataccata tttattttca ttttataggt ctacctcttg cttctttgtc
      721 tgtgttaatc gcttttcttg tttttataac tgctctatac aagtcttaac tttttctgcc
      781 tgtttaattt tttctcgtat ctctaatatt ttattgtgta agctcttttt ttctttcttc
      841 atattggcga cttccgattt tcatttgcta atgactaaga tcttgctttc gcccaaatgc
      901 tcttttagat atttcttggc actctcaaat aaaataatct ctgctgtatc aacgttagct
      961 gatatgccct ctgcaagagc cttcggagaa cgcacgcacc tgttgaggtg tatatgtaca
     1021 ctcttgtaaa caagggacta ttcctctgtg tccgttgctt cctcttgcac ttctatgttt
     1081 tcttctgttt gttctctttt ctctatgatt tttaggattt tttgattgac tgctcccttt
     1141 tcataaaggc gtctatctct cttttttctc tctttctatt tcgactgaat gatgggcttt
     1201 tttcttttgt tttgtaactg cttgatttct ccatctgtca ttaaaatttt ttcatctatg
     1261 tttttcattt tctattttcc tctctttctg ttttgagcaa caaaaaaaca gtaaaccatt
     1321 tttttgattt actgttttct a
//
LOCUS       DARYSY010000145         1322 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYSY010000145 DARYSY010000000
VERSION     DARYSY010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            270..1121
                     /locus_tag="TVR04_002001"
     CDS             270..1121
                     /locus_tag="TVR04_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270654.1"
                     /translation="MKNKLLKSLLLSSAIFATFGTSLVFAENSETRLSDIPPSTLATE
                     APSAAESTIDPIPTERSIAKVAEEESAEVTLEEYLENVADFEDVDIEEVRQAFTEDHL
                     EHILYFGRGTCYHCRQLSPELKEFNTLIDGKVEYYDVDREDFDPSAQEFLFKTVGIPG
                     TPTILYLKNGQPVAGWAGGGVTAQQLYNYFYFEKRPESPTKEDNKQAESTENITIEMT
                     AFNSSEQLQEQANLKNIGAIQVLITKAKTFPKTGEQGSTKLFQLGMVCLIASALLIAN
                     RIKMTSR"
BASE COUNT          473 a          230 c          227 g          392 t
ORIGIN      
        1 acctgatatc ttcactataa gagtagtaga ggcatttaca atgaacgaga acttcgattt
       61 cctaacagca gcctatgatc aagaagtgtc atagaaaata aatagctagg ctgaagcctt
      121 catattaaat ttttgtagtg gttttatcca ctccaaaatg ataaagtcaa cagtcatttc
      181 aagatattat agataccatt taagacttag gcatttttgt gatgttaaaa cgtgtaaagt
      241 aaagctatca actattaagg agcttcgcca tgaagaataa attattaaaa tcacttttac
      301 taagctcagc tatattcgct acatttggaa caagtctagt ttttgccgaa aattctgaaa
      361 ctagattatc agatatccct ccatcaactc tagctactga agcgccatca gccgccgaat
      421 cgactattga tcctataccc actgaacgaa gcattgccaa agttgctgaa gaagaatctg
      481 cggaagtaac gcttgaagag tatttagaaa atgttgctga tttcgaagac gttgatattg
      541 aggaagttcg tcaagctttt acagaggatc atcttgaaca tatcctctat tttggtcgtg
      601 gaacctgtta tcactgccgt caattgtcac cagaattaaa agagtttaat accttgattg
      661 atggtaaagt agaatactat gatgtcgata gagaagactt tgacccatca gctcaggagt
      721 ttttatttaa aacagttgga atcccaggaa caccaacaat actatatctg aagaatggtc
      781 aacctgttgc tggctgggct ggtggaggag taacggctca acaactttat aattattttt
      841 attttgagaa acgtccagaa tctccaacaa aagaagataa caagcaggca gaatcaactg
      901 aaaatatcac cattgaaatg acagcattta atagctcaga acagttacaa gagcaagcta
      961 atctgaaaaa cataggtgct attcaagtat tgataacaaa ggctaagact tttccaaaaa
     1021 ctggagaaca aggctctaca aagctttttc aattaggcat ggtatgcttg atagcatctg
     1081 ctttacttat cgcgaatcgt atcaaaatga caagcagata gtctaacata tagttacttg
     1141 aaaaagcaag aaatcttttc actttcaggg tcttctcttc catttttgta atgatcaact
     1201 caaaatttct catatcatta gataatgcta ttttaatatc atatttgaat tcaaaaataa
     1261 aaattacata aaaaatactt gacgaataat tataaaacat gtatgctaaa atcgagataa
     1321 ag
//
LOCUS       DARYSY010000146         1250 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYSY010000146 DARYSY010000000
VERSION     DARYSY010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1250
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            203..586
                     /locus_tag="TVR04_002002"
     CDS             203..586
                     /locus_tag="TVR04_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HEL1270655.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIAMFNSFTGKDEPRYKHEQDRMV
                     EYLAQNYEGIEKVEFTEIDHNAMTGTYSFYAIINTKIKVDFTLWGLKGEIYVNELSSR
                     NHGYFLKKLDTPNEKPDISQIEVKY"
     gene            597..842
                     /locus_tag="TVR04_002003"
     CDS             597..842
                     /locus_tag="TVR04_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270656.1"
                     /translation="MISEKDYNKIANDVYKVDSSKVKNPVIEGYPVANEKYRVLEAED
                     NPDNGMQAMAVAPIKGGEVGKNYIVIVYDGINHLTAI"
     gene            858..>1250
                     /locus_tag="TVR04_002004"
     CDS             858..>1250
                     /locus_tag="TVR04_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270657.1"
                     /translation="MMKKQQNKRRKLIGIVALITILGGIITMGWFNGEELKKEKYRQE
                     QDRVVKYIGEHIELGNGQPITKIEFIEFQLETATTGTWSITAIVNEKYLIHFSEDRLG
                     EEIRTSYYSPKEFKQYSEKMRNNMTNVET"
BASE COUNT          491 a          153 c          259 g          347 t
ORIGIN      
        1 aaaaactata ataaactctc tgaaaaagta tatgatgttg atgctaataa agtaactatt
       61 cctgttagaa aaaatacgga tattcttaat cgttatgtca aagtccttga agccgaagac
      121 aatcctggca atggtatgca gtttacggtg tcaaagagta ataggaatgt tctagcttta
      181 aattataaac taaggagctt ctatgacagt aaaaaagaaa gtcatcattt tactaggaat
      241 ggtagcaatt ttagtaatgg gaggtatagc aatgtttaat tcatttacag gtaaggacga
      301 accaaggtat aaacatgagc aggatagaat ggtagagtat ttagcacaaa attatgaagg
      361 tattgagaaa gttgagttta cagagattga tcataatgct atgacaggaa catactcatt
      421 ttatgccata ataaacacta aaattaaagt tgattttacg ctgtggggat taaaaggtga
      481 aatctatgtg aatgaactgt cttccagaaa tcatgggtat tttcttaaaa agttagatac
      541 gcctaatgag aaaccagata tttctcaaat tgaagttaag tactaggagg aagaatatga
      601 tatcggaaaa agattataac aaaattgcta atgatgttta caaggttgat tctagtaaag
      661 taaaaaatcc agttatagaa ggatatccag ttgccaatga aaaataccgc gttcttgaag
      721 ctgaagacaa ccccgacaat ggtatgcagg ctatggctgt agctccgatt aagggtggtg
      781 aggtgggtaa gaattatatc gtgattgttt atgatggaat taatcattta acagcaattt
      841 agcaattaaa ggagttgatg atgaaaaagc aacaaaacaa acgacgaaaa ctaattggca
      901 tagtagcctt aataacaatt ttaggaggaa taataacaat gggttggttt aatggcgaag
      961 agctaaaaaa ggaaaagtac agacaagagc aagatagggt agtgaaatac ataggagagc
     1021 atatagaact aggtaatggt cagcctataa ccaaaattga gtttatagaa tttcagttag
     1081 aaactgcaac caccggaact tggtcaataa cagcaattgt taatgagaaa tatctgattc
     1141 atttttcaga agatagatta ggtgaagaaa tacggacttc ctattattct ccaaaagaat
     1201 ttaagcaata cagtgaaaag atgaggaata atatgactaa tgttgaaaca
//
LOCUS       DARYSY010000147         1229 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYSY010000147 DARYSY010000000
VERSION     DARYSY010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..>1229)
                     /locus_tag="TVR04_002005"
     CDS             complement(<1..>1229)
                     /locus_tag="TVR04_002005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270658.1"
                     /translation="LLDDKHREVLLNGYLNQQIENDRTRQEENPFKEGMSVRYKGKEY
                     TITAINDTTSPKTIELEDSTGLMNGFITGSETILFNDYKNLDLEVYKSSEKQSIDKEE
                     LVEQISFEDIDNNNEEKVKKDKKTDRENIEGVSEVSLENYKIINEEENLPPSQRLKNN
                     IEAINVLKTLEKENRSARKDEQEILAKYIGWGGLSDVFDEEKEGQWLEARNFLKENLT
                     GEEYNRAIESTLTAFYTPKVVIDAIYESLSNLGFEKGNILEPSAGTGRFIGNLPEEMK
                     ESNFYGVELDSISGQIAKELYPNSNIQIKGFEETNFSNNLFDVAIGNIPFGEFKVADR
                     EYERNNFLIHDYFFAKTLDKVRDGGIIAFITSSGTMDKKSEDVRRYISERAEFLGAIR
                     LPNTTFKGVAGTEVTSD"
BASE COUNT          326 a          235 c          149 g          519 t
ORIGIN      
        1 tatctgaagt tacttctgtt ccagctaccc ctttaaatgt agtatttggt agtcttattg
       61 ctcctaagaa ctctgctctt tccgatatat atcttctaac atcttcactt tttttatcca
      121 ttgttcctga agatgttata aaagcaatta tgcctccatc cctaacctta tctaaagttt
      181 tagcaaaaaa ataatcgtga attagaaagt tatttctttc atactcacga tctgctactt
      241 taaattctcc aaaaggaata tttcctatgg ctacatcaaa taggttatta gaaaaattgg
      301 tttcttcaaa tccttttatt tgtatattgg aattagggta aagttctttg gcaatttgtc
      361 cactaatgct atctaattca actccataaa agtttgactc tttcatttct tcaggtagat
      421 ttcctataaa tctacctgtc ccagcacttg gttctaatat atttcctttt tcaaagccaa
      481 gattagaaag actttcatag atagcgtcta taactacttt cggcgtataa aaagctgtta
      541 gggttgattc tattgcccta ttatattctt ccccagttag attttctttt aaaaagttcc
      601 ttgcttcaag ccattgacct tccttttctt catcaaatac atcagaaagt cctccccagc
      661 cgatatactt tgccaaaatt tcctgttcat cttttcttgc acttctattt tctttttcta
      721 aggtctttaa gacatttata gcttcaatgt tgttttttaa tctctgtgaa ggtggtaggt
      781 tttcttcttc attaataatt ttatagtttt ctaaagaaac ttcagaaacc ccttctatat
      841 tttctctatc agtctttttg tcttttttaa ctttttcttc gttattattg tcaatatctt
      901 caaagctgat ttgttctacc agttcctctt tatcaataga ttgtttttca ctagatttat
      961 atacttctaa atcaagattt ttgtagtcat taaaaagaat tgtttcactt ccggtaataa
     1021 agccattcat tagtcctgtg ctatcttcta gttctatagt tttaggactt gtagtatcgt
     1081 taatggcggt tatagtgtat tctttccctt tgtatctaac actcatacct tctttaaatg
     1141 gattttcttc ttgccttgtt ctatcatttt ctatttgctg atttaaatat ccatttaaaa
     1201 gcacttctct atgtttgtca tcaagtaaa
//
LOCUS       DARYSY010000148         1199 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYSY010000148 DARYSY010000000
VERSION     DARYSY010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..700)
                     /locus_tag="TVR04_002006"
     CDS             complement(<1..700)
                     /locus_tag="TVR04_002006"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270659.1"
                     /translation="MGADRRTERRGLSEISEIEEEHGYDPTRNRGKGDNPNIKNEEVE
                     STSFFSAKNQGEQISFSNPISQREIDTFLIHGGNHEDGRLAVIAEFSKGKSLEEQVNF
                     LKEIYKGANGLEIEGRKISAWFGKEGAIFKDGDEARYREGQIVSWKDLANNINNLLDR
                     GEFASNVEVIESATYEREKIAETLLYLKRDLSDETKDRYLASLNDIKGRGFQDEKENL
                     GKKLEDKNFINKLRK"
     gene            complement(586..1044)
                     /locus_tag="TVR04_002007"
     CDS             complement(586..1044)
                     /locus_tag="TVR04_002007"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1270660.1"
                     /translation="MNEKVTLAGKEYLMEEGIYTPIVKENYFERQGGTYKMEELEEGM
                     EVLIPNMAIPKEIDLKKLNRWGRMRLNFLKENKEEDYQIMYLQGILMDHLLSKEKEIE
                     DFITREEVKMMETWGLTEELKEEDYLKYLRLKKNMDMTLQEIGEREIILI"
BASE COUNT          285 a          286 c          121 g          507 t
ORIGIN      
        1 cttttctgag tttatttata aaatttttat cttcaagttt tttcccgaga ttttcttttt
       61 catcttggaa gcctctccct tttatatcat taagactcgc tagatatctg tccttagttt
      121 catcactaag atctctcttt aaatacaata atgtttctgc tattttttct ctttcatatg
      181 tggcactttc tataacctca acattgctag caaattctcc tctatctaat aaattattaa
      241 tattattagc taaatctttc caagaaacta tttgcccttc tctatacctt gcctcatctc
      301 catctttaaa aattgctcct tcctttccaa accatgcaga tatctttctt ccttcaattt
      361 caagaccatt agctccctta tatatttctt tcaaaaagtt tacctgttct tctaaagatt
      421 tacccttaga aaattctgct attactgcta atcttccatc ttcatgattt cctccatgta
      481 ttaaaaatgt atctatttct ctttgactta ttggatttga gaaggatatt tgctctccct
      541 gatttttagc agaaaaaaag gaagtagact ctacttcctc attttttata ttaggattat
      601 ctccctttcc cctatttctt gtagggtcat atccatgttc ttcttcaatc tcagatattt
      661 cagatagtcc tcttctttca gttcttctgt cagcccccaa gtttccatca ttttgacttc
      721 ttccctcgta ataaagtcct ctatctcttt ttcctttgat agaagatgat ccatcaatat
      781 cccttgcaaa tacattatct gataatcctc ttctttgttc tccttgagaa agttcaatct
      841 catccttccc catctgttga gtttctttaa atctatttcc ttgggaattg ccatattggg
      901 tattaggact tccatgcctt cctccaattc ttccatcttg tatgtccctc cctgtctctc
      961 gaagtaattc tccttgacga ttggtgtgta aatcccctcc tccatgaggt attccttgcc
     1021 tgccaatgtt actttctcgt tcatcttcca agcctccttt tttaaaattt atttcaccgt
     1081 ttatatcaga acttaattta ttataacgct ccttaagctc ttttgtctgc tccaaatctt
     1141 ttctttcttg aattttctct aaaatttcta atctttttat ttcacttccc aaatcaagt
//
LOCUS       DARYSY010000149         1193 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYSY010000149 DARYSY010000000
VERSION     DARYSY010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..214)
                     /locus_tag="TVR04_002008"
     CDS             complement(<1..214)
                     /locus_tag="TVR04_002008"
                     /inference="COORDINATES: protein motif:HMM:NF012879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1270661.1"
                     /translation="MKKRINTTVDWTYIPCDMTDIYVGVTVNRGSLHDGHKKGIAHFL
                     EHMLLCISDKDILNKKYNIRGTTYFDK"
     gene            complement(339..575)
                     /locus_tag="TVR04_002009"
     CDS             complement(339..575)
                     /locus_tag="TVR04_002009"
                     /inference="COORDINATES: protein motif:HMM:TIGR04067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Apre_1838 family putative sactipeptide
                     bacteriocin"
                     /protein_id="HEL1270662.1"
                     /translation="MKLINPIGREVSSNASANHAVPMACMCGAWSNFSGTRTTSDTCS
                     HCGCNCYNSSGNKTKYRVNNYTIANDSNRATPVS"
     gene            complement(640..1152)
                     /locus_tag="TVR04_002010"
     CDS             complement(640..1152)
                     /locus_tag="TVR04_002010"
                     /inference="COORDINATES: protein motif:HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1270663.1"
                     /translation="MPLLLWDKGRNSLERRQSFTSGANLSALSRIHKRSITHEPNKIV
                     SLNGCCIPGMRRLYVDVEGNFLPCERVGKSPYIGNVNTGLDFDSIEKYYVNDYVEKSL
                     PDCSQCWAVPLCGLCYSHCYTEEGIDIERKRQACDDHRYSMMQHLIYYHELMKIDPEF
                     INDLNNVEVV"
BASE COUNT          393 a          232 c          141 g          427 t
ORIGIN      
        1 ttttgtcaaa ataagtagtt cctctaatat tatatttttt atttaatata tctttgtccg
       61 aaatgcataa caacatatgt tcaagaaaat gtgcaattcc ttttttgtgt ccatcatgta
      121 gagatcccct atttactgtt acgcccacat agatatctgt catatcacaa gggatatatg
      181 tccaatcaac tgtagtatta attctttttt tcacaataat caatcccttt taaaaaaata
      241 caagggttag taacagatta catagactac tcactatcgc aaatcataat ttattactaa
      301 ccctcatact taaattcttt tatacaacaa tatatattct atgatactgg agttgctcta
      361 ttagagtcat tggctatagt atagttatta actctatatt tagttttgtt tccagaagaa
      421 ttgtaacagt tacaaccaca atgagaacaa gtatcactag ttgttcttgt cccactaaaa
      481 tttgaccaag ccccacacat gcaagccatt gggactgcgt gattagctga agcatttgaa
      541 gatacttctc ttccaatagg attaattaat ttcataataa accatccttt ctgtactgtt
      601 aactaatatt ttaaatagct ttcgtctatg aaatctcaat taaacaactt ctacattatt
      661 aagatcattg ataaattctg gatctatttt cattagttcg tgataataaa ttaaatgttg
      721 catcatacta tacctatgat catcacaagc ctgccttttc ctttcaatat ctattccttc
      781 ctcggtataa caatgagaat aacaaagtcc acaaagaggt actgcccaac attgactaca
      841 atcaggcaaa gacttctcta cataatcatt tacataatat ttttctatac tatcaaaatc
      901 taatcctgtg tttacatttc caatgtatgg cgatttccca actctctcac acggtaaaaa
      961 attaccttca acatctacat acaatcttct cattccagga atacaacatc catttaaact
     1021 aactatttta tttggttcat gtgtaatcga acgtttgtgt attctagata acgcagaaag
     1081 atttgctcca gatgtaaaag attgcctacg ttcaagagaa tttcttcctt tatcccacag
     1141 aagtagtggc atcctatctt ctaatagttg acttttatta gaaactcgat ttt
//
LOCUS       DARYSY010000150         1138 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYSY010000150 DARYSY010000000
VERSION     DARYSY010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            2..433
                     /locus_tag="TVR04_002011"
     CDS             2..433
                     /locus_tag="TVR04_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270664.1"
                     /translation="MKKPTKVFIALMILIGGLLMVFSLNDKITEEQQKKDLETSIAKL
                     LVHDYEGIKTIKFTGWGHSRETGSWGTTVVINGENEIGFSFDGLSSLEEISSIVSDEN
                     IQLTESENAIENPRIRDRISRIQKTSLKGIDIIYSEDDKEN"
     gene            568..990
                     /locus_tag="TVR04_002012"
     CDS             568..990
                     /locus_tag="TVR04_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270665.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNNPDINHKSEEELRNYEYEV
                     SLVKALKNSYKGIEEITITNPHYTIPPGNWHCEVSIKFLDGETIFFGTSYSLEEKTFS
                     TGGIKRKNIAGWEYLEANKGETDWEVSVSYSDGEKGYQ"
BASE COUNT          419 a          136 c          250 g          333 t
ORIGIN      
        1 catgaaaaag ccaacaaaag tttttattgc tttaatgatt ctaataggag ggttgcttat
       61 ggtttttagt ttgaatgata aaatcacaga agaacaacaa aaaaaggatt tggaaactag
      121 tattgctaag ctgctggttc atgactatga agggattaaa accattaagt ttacaggctg
      181 gggacattct cgtgaaacag gttcgtgggg gacgacagta gttataaatg gagaaaatga
      241 aataggcttt tcatttgatg gtttgtctag tcttgaagag attagtagta ttgtttctga
      301 tgaaaacata caacttacag aaagtgaaaa tgcaattgag aatcccagaa taagagatag
      361 aattagcaga atacaaaaaa cgtctttgaa aggtattgat attatctact cagaagatga
      421 taaggagaac tgatatggct atttctgaca gtagttataa aaaattagca gaacagctct
      481 gtaatgtcga acctaggaaa gcaaagtcca ataatgtagt tcggtatggc actgacaggc
      541 aggagactag ttgaaaggag aactttcatg aaaaaatcga caaaagcttt tattgcttta
      601 atgattctaa taggagggct gcttatggta tttagtttga ataacccaga tatcaaccac
      661 aaatctgaag aagagttacg gaattatgag tatgaagtta gtttggtgaa agcgttaaaa
      721 aactcctaca aagggattga ggaaatcacc atcacaaatc cgcactatac tataccgcca
      781 ggaaattggc attgtgaagt tagtattaaa tttttagatg gtgagactat cttttttggt
      841 actagttata gtcttgaaga aaagactttt tcaacaggag gaataaaaag aaaaaatata
      901 gcaggttggg agtatttaga ggccaataaa ggagaaactg attgggaagt gtcagtttct
      961 tattctgatg gtgagaaggg atatcaatga gttattttat ttattcagat aaacaattaa
     1021 atgtttttaa tagaggcaaa catgtttaca gtgtcagcga ggattatgca aatagatatg
     1081 attatgactt aattgtcgat aaaccagata atcaattaag gtcaggtgag atcagtag
//
LOCUS       DARYSY010000151         1080 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYSY010000151 DARYSY010000000
VERSION     DARYSY010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            86..>1080
                     /locus_tag="TVR04_002013"
     CDS             86..>1080
                     /locus_tag="TVR04_002013"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1270666.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADTDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEIVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSVIYKSIYEGADIKESILGMMSNEFR"
BASE COUNT          293 a          265 c          261 g          261 t
ORIGIN      
        1 agactaagcc agcagacctt ttctattaga gttaggcctt gtcttatgat ataataagat
       61 gattagctct taaaggagaa taaaaatgcc aaaacaaaag gtagccattt tgggacctgg
      121 ctcttggggc acagccctgg cacaggtcct aaatgacaac ggacatgagg tccgactatg
      181 gggaaatatc cctgaacaaa tcaacgaaat caacacacgc catactaata gtcattattt
      241 taaggatatc gtcctagatg aagccatcaa ggcaactctt gatctgaagg aagctctagc
      301 agacactgat gctatcctct ttgttgtccc taccaaggta acccgtctgg tcgctaagca
      361 ggtcgctcag gtcttagacc acaaggctat tgtcatgcat gcctcaaagg gactagagcc
      421 tgggacccat gagcgcctct caacgatcct cgaagaggag attcctgccc agctgcgcag
      481 tgagatcgtg gttgtgtctg ggcctagcca tgccgaggag accatcgttc gtgacattac
      541 cctaatcact gcagcctcaa aggacatcac agctgctagg tatgttcaga ccctctttag
      601 caaccactac ttccgtctct acaccaatac tgatgtgatc ggtgttgaaa ccgctggcgc
      661 tctcaaaaac atcattgctg ttggagccgg tgccctgcat ggccttggct atggtgacaa
      721 tgccaaggct gctgtcatca cacgcggtct tgcggaaatc acacgactag gggtcaagct
      781 tggggcagac cctctgacct atagcggcct atctggtgtt ggtgatttga ttgtcacagg
      841 aacatctgtg cattcacgca actggcgagc tggtgctgct cttggtcgcg gcgaaaagct
      901 caaggacatc gaaaacaata tgggcatggt gattgaaggc atttccacaa ccaaggtagc
      961 ctacgaaatt gcccaggagc taggcgtcta tatgccaatc accagtgtga tttacaaatc
     1021 tatctacgaa ggtgctgaca ttaaagaaag cattctgggc atgatgtcaa atgaatttcg
//
LOCUS       DARYSY010000152         1052 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYSY010000152 DARYSY010000000
VERSION     DARYSY010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>1052
                     /locus_tag="TVR04_002014"
     CDS             <1..>1052
                     /locus_tag="TVR04_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEL1270667.1"
                     /translation="RYNPFAYLKSEKDILKLVQTIIANTKGEGEKSTEDFWVKAEKLY
                     YTALIGYIWYEAPKEEQNFTTLLAMIDASEVREEDENFKNAVDYMFEALEKEKPNHFA
                     VKQYKKYKLAAGKTAKSILISCGARLAPFDIEELRDLMKEDELELDTLGEKKTALFVI
                     ISDTDDTFNFVVSIMYSQLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGLIPKFEKL
                     IATIRSREISACIILQAQSQLKSIYKDNADTIVGNCDSTLFLGGKERTTLKELSESLG
                     KETIDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGVRPFLSDK
                     FDITKHKNYKLLEDYD"
BASE COUNT          432 a          143 c          192 g          285 t
ORIGIN      
        1 agatataatc cctttgcata cttgaaaagt gaaaaagata ttttgaaatt agtacaaaca
       61 ataattgcaa atactaaggg agaaggagaa aaatcaactg aggatttttg ggtgaaagct
      121 gaaaaactct attacacagc acttatagga tatatctggt atgaagctcc taaagaagaa
      181 cagaacttta caactttact tgctatgata gatgcaagtg aggtaagaga agaagatgaa
      241 aattttaaaa atgcagtaga ctatatgttt gaagcattag aaaaagaaaa gccaaatcat
      301 ttcgcagtaa aacaatacaa gaaatacaaa cttgcagcag gaaaaactgc caaatcaatc
      361 cttatatcct gtggagcaag gcttgctcca tttgatatcg aagaactaag ggacttaatg
      421 aaagaagatg aactggagct tgatacactt ggagaaaaga aaacagcttt attcgtaata
      481 atatcggata cagatgatac atttaacttt gtagtatcaa taatgtactc acaattattt
      541 aatctattat gtgataaagc agatgatgaa tatggcggaa gacttcctgt tcatgtgaga
      601 tgcctacttg atgaattcgc aaatatcggc ttaattccta aatttgaaaa gctgatagca
      661 actattagaa gtagagaaat atcagcttgt ataatattac aggcacaatc acaactaaaa
      721 agtatctata aagataatgc cgataccata gttggcaatt gtgattctac attattttta
      781 gggggcaaag aaagaacaac attaaaagaa ttatctgaaa gcctaggcaa agaaaccata
      841 gacctatata acacatcaga aacaagatca aatcaaaaga gctttggttt aaattatcaa
      901 aaaaccggta aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt
      961 atataccaac taagaggagt aagacctttc ttatctgata aatttgatat tacaaagcat
     1021 aagaattaca agttattgga agattatgat aa
//
LOCUS       DARYSY010000153         1006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYSY010000153 DARYSY010000000
VERSION     DARYSY010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(1..903)
                     /locus_tag="TVR04_002015"
                     /pseudo
     CDS             complement(1..903)
                     /locus_tag="TVR04_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003026705.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
BASE COUNT          311 a          217 c          131 g          347 t
ORIGIN      
        1 gacaaacatt ttttcactat caattacatc attttccttg ataacttgtc cagtctccca
       61 agacatatga tttgatacag tttttataaa atctctaaaa actggagaat catttactgt
      121 aatatgatgc tcaaagttcc aatcttcacc gtgattttcg ccagatagag caataacatc
      181 ttcaatatac tctttttcgg taaaaatatt caactcatct ttaccgaatt taactagatt
      241 aaccacctct tcataacgtt ctactgcatt attaatattt tgtaagttct tacttgcatt
      301 cgagttctta cgaccagaac gcttgtatcc atcgttacgc agatcaataa atttcactcg
      361 ctgtttggct tcatgtttat ctcctacttt gaatacataa atagaagttt ggacactaga
      421 cttaccaata aaaatatcca ttggcatttt gatagacgct aaaagcgtgt tgtgctctaa
      481 aatcttctga ttgatttctt ttgccttccc tgcacctgct gaatcttgaa taataatgga
      541 agcatagcca cctttcatca tagacaaagc acgcttgaca aagttcatac cattacccgt
      601 ttcggaataa ggaggattta aaagaaaaac atctgctgga aaccgctcat tttctttccc
      661 ataaccatat ttcccatcaa actttttcaa actatcatct tgcaagatat tactggaacc
      721 atctcccatg agaatcatgt ttagaacggc caacatgtaa atttctggaa gaatttcaat
      781 cccaagaatt tgttcagcct tgattttctc ttccttttct ctgagttcat cggggcttgt
      841 aatttccttt ttagcgtcat ctaacatcaa attcatagca gccaccaaca gaccacccga
      901 accctctcat gtcaaactta tgacaaaatt ctgatgctat gtaaataaaa aagagtagtc
      961 ttaactactc tcataatgtt tttagattta gataatctta tttgtt
//
LOCUS       DARYSY010000154          999 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYSY010000154 DARYSY010000000
VERSION     DARYSY010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..275
                     /locus_tag="TVR04_002016"
     CDS             <1..275
                     /locus_tag="TVR04_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1270668.1"
                     /translation="PELKELKKILNKHGVKFSVMKDKETGNHSVFFQSKDIKVMEHAF
                     KKAVKASEKKADRKDSITKTINKFKDMAKDTISKDKVKNKHKEQSL"
     gene            272..>999
                     /locus_tag="TVR04_002017"
     CDS             272..>999
                     /locus_tag="TVR04_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1270669.1"
                     /translation="MISNLKTFENKNFGKLTVIEKDGEFFFIANEVATMLGYVNPRKA
                     IYDHVDEEDKGVTKWNTPGGIQNISIINESGLYSLILSSKLPQAKIFKAWVTREVLPS
                     IRKNGGYIVGQEKKTNEDLLADAILVANRIIAEREEEIEELRPKADYYDKLVDYNLLT
                     NFRNTAKELGIPQNQFISFLMDKGLIYRDKKKKLLPYADKNKGYFEVKEWIDPLGTLV
                     GIQTLITPKGRHYLLILLDSEGFY"
BASE COUNT          428 a          130 c          181 g          260 t
ORIGIN      
        1 atcctgagtt aaaagaatta aagaaaattt taaacaaaca cggagtgaag ttttctgtta
       61 tgaaagataa ggaaactggt aaccactctg tgttttttca atctaaggat ataaaagtaa
      121 tggaacacgc ctttaaaaaa gcagttaagg cttctgaaaa aaaggccgat agaaaagatt
      181 caataacgaa gactataaat aagtttaaag atatggctaa ggacaccatt agtaaagata
      241 aagttaaaaa taaacataag gagcaaagct tatgataagt aatctaaaaa catttgaaaa
      301 taagaatttt gggaaactca ctgttattga aaaagatggt gagtttttct ttatagcaaa
      361 tgaagtagca actatgctag gatatgtcaa tcccagaaaa gctatttatg accatgtaga
      421 cgaagaagat aagggtgtaa cgaaatggaa cacccctgga ggaatacaga atatttcaat
      481 aattaacgaa tcaggattgt attcacttat cctctcatca aaactaccac aagcaaaaat
      541 attcaaagct tgggtaacta gagaagtctt accaagtatt agaaaaaacg gaggatatat
      601 agtagggcaa gaaaagaaaa ctaatgaaga tctacttgca gatgcaattc ttgtagccaa
      661 tagaattatt gctgaaagag aagaagaaat tgaagaatta agaccaaagg cagattatta
      721 tgacaaatta gtagattata acctacttac aaactttaga aatactgcca aagagttagg
      781 aataccacaa aatcaattta taagttttct aatggataag ggattaattt acagagataa
      841 gaaaaagaaa ctcttacctt atgcagataa gaacaaggga tattttgaag taaaagaatg
      901 gattgatcca ctaggtacac ttgtaggaat acaaacatta ataacaccaa agggaagaca
      961 ctacctacta attttattag atagtgaagg tttctacga
//
LOCUS       DARYSY010000155          960 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYSY010000155 DARYSY010000000
VERSION     DARYSY010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>960
                     /locus_tag="TVR04_002018"
     CDS             <1..>960
                     /locus_tag="TVR04_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019034967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEL1270670.1"
                     /translation="KRKITDLDKMKIEENKKAIRSGYDIDILPSDLITYGNDAKKLLV
                     ELQNHNERMFVITILFTNMEKSRKKLSNIIFQLNSIAGRHNCVLKNLNYRQEQGLISS
                     LPLGKNEIEIKRGLTTSSTAVFIPFTTEELCLEGESLYYGLNALSRNIIMTDRKLLKN
                     PNGLILGTPGSGKSFSAKREITNAFLITQDDIIICDPEGEYGNLTKALGGEVIKISPT
                     SKDYINPLDINVDYADEDNPLSLKSDFILSLFELVVGKEGLSAEETSVIDRCLPILYK
                     DYFDNPIPENMPILEDLYNLLLKQEENVGKKLAVEMEIYVKGSL"
BASE COUNT          377 a          125 c          173 g          285 t
ORIGIN      
        1 taaaagaaaa ataacggact tggataaaat gaaaattgaa gaaaataaga aggctataag
       61 atcaggatat gatattgata ttcttccaag cgatttaatt acctatggta atgatgctaa
      121 gaaactattg gtagaacttc aaaatcataa tgagagaatg tttgtaataa ctattttgtt
      181 tacaaatatg gaaaaaagta gaaagaaatt gagtaatata atctttcaac taaattcaat
      241 agcaggtagg cataattgtg tattgaaaaa tcttaactat agacaggaac aaggactaat
      301 ttcctccctg ccacttggaa aaaatgaaat cgaaataaaa agaggactta caactagctc
      361 tacagcagtc tttattcctt ttacaacaga agagttgtgc ttagaaggag agagcttata
      421 ctacggatta aatgctttaa gtcgtaacat cattatgacg gatagaaagc ttttaaagaa
      481 tccaaacggt ttaatacttg gaacgcctgg tagcggtaaa tctttttcag ctaaaagaga
      541 aattaccaat gcttttttaa tcacacaaga tgacatcatt atctgtgatc ctgaaggtga
      601 gtatggaaat ttaactaagg cattaggtgg agaagttata aaaatatcac caacaagtaa
      661 ggattatata aacccgttgg atataaatgt agactatgcc gatgaagaca atcccttatc
      721 tttaaagtct gactttattc tttcactgtt tgaacttgta gtaggaaagg aaggattaag
      781 tgcagaagaa acttcagtaa ttgatagatg tcttccaata ttatataagg attacttcga
      841 caatcccatt cctgaaaata tgccaatttt agaagattta tataatttac ttttaaaaca
      901 agaagaaaat gtagggaaaa aattagcggt agaaatggaa atttatgtca aaggtagtct
//
LOCUS       DARYSY010000156          938 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYSY010000156 DARYSY010000000
VERSION     DARYSY010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..938
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>938
                     /locus_tag="TVR04_002019"
     CDS             <1..>938
                     /locus_tag="TVR04_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1270671.1"
                     /translation="NLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINT
                     LSANVNQQNENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNR
                     AYSIYRSYLTQTSSLVDNTDKTAVINQFVAQIDSQINQLESSVAGYRIQHAGSGVQQS
                     YSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVANEDGVL
                     HLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDD
                     NGETLDLIVKLSSIDNAATKTKNGNYFKVESKLQLK"
BASE COUNT          349 a          151 c          166 g          272 t
ORIGIN      
        1 taatttacaa atccaaaaag aacagttaga gctattaaaa gcaagtattg aagctggaaa
       61 cagtcaattt ccagaaaaag ataattatgg atattatcaa acatttattg actacttaaa
      121 tcagataaac accttatcag ccaatgtaaa tcagcaaaat gaaaatgtct cttcacaaaa
      181 tactgcagct agcaatcagc aagtagaaat tgagaatgcc atcaaaggtc tcacaagtca
      241 aatttcagat tatcaatctg ttcgctcggc gattcaaaat ggaacagtgg tagatcttga
      301 taatcgggct tattctatct ataggagtta tctaactcaa acatcgagtt tggtagataa
      361 tactgataaa accgctgtta ttaatcaatt tgttgctcaa attgatagtc agatcaatca
      421 actagagagt agtgtagctg gttatcggat tcagcatgct ggttcaggag tgcaacaatc
      481 ttactcttca actctagaga gtcaactggc ttccttaaaa gcgcaaagca taaccaaagt
      541 tgagcaagag ttgtctgctt tgtcgaatca aattacagaa ttagagggaa caaataaact
      601 tcagaagaac acatcatcta agacctctat agttgccaat gaagatggtg tgttgcatct
      661 taatcaggaa tttattggtg caaatattgt tcctgaagga acaatatttg ctcaagttta
      721 tccagaaatg aaaaaaggaa ctgttgtaaa aatcacaggt tatttacctt cgacggaaat
      781 atcaagtatt tctattggag atacagcacg attttccacg aaagatgata atggcgaaac
      841 tcttgattta atagttaaat tatctagtat tgacaatgct gcaactaaaa caaaaaatgg
      901 gaattatttt aaagttgaat ctaagttaca gcttaaag
//
LOCUS       DARYSY010000157          872 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYSY010000157 DARYSY010000000
VERSION     DARYSY010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..844)
                     /gene="galU"
                     /locus_tag="TVR04_002020"
     CDS             complement(<1..844)
                     /gene="galU"
                     /locus_tag="TVR04_002020"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1270672.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKAGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTI
                     AVMRVPHEEVSNYGVIAPQGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIF
                     AILEKQAPGAGNEVQLTDAIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKH
                     PQVKD"
BASE COUNT          194 a          232 c          215 g          231 t
ORIGIN      
        1 cgtccttgac ctgagggtgc ttgagagcat agtcaagtga ggtcttcata aagccaaact
       61 tgtccccaac atcataccgc tctcccttaa actccctcgc aaaaacccgc tgtgtcttat
      121 tgagcttgtc aatcgcatcg gtcagctgta cctcattgcc agccccaggc gcctgcttct
      181 ccaatatggc aaaaatctca ggcgtcaaca aatatcgacc aataatcgct aagtcactcg
      241 gtgcctcatc tggacttggc ttctcaacaa aggtctccac actatacaag cccttaacag
      301 ccttcccttg cggtgcaatc acaccataat tggaaacctc ctcatgcggt accctcatca
      361 ctgcaatcgt tgaggcgtgt gtgcaatcat aatcctcaat aagctgcttg gtcaagggct
      421 tggcactagg attggtaata tccatgaggt catcccccag catgaccaca aagggctcat
      481 tgccaacaaa ggccttggct tggaggacag cgtcccctag tcctctaggg tggctctgac
      541 gaatgaagtg caggttgatg gcagtggtct catcaacgag cttgagtagc tcggttttgc
      601 ccttggcttg gagattgtat tcgagctcga agttggagtc aaagtggtcc tcgatagagc
      661 gtttggcctt gccggtgacg acaagaatct cctcgatacc tgcctttagg gcttcctcga
      721 cgatgaattg aatggttggc ttatcgacga ttgggagcat ttccttggcc agtgccttgg
      781 tggcgggcag gaagcgagtg cctaggccgg cggctgggat aatggctttt ctgacctttg
      841 tcatgagttc ctccttgatt tgtggttcct ta
//
LOCUS       DARYSY010000158          860 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYSY010000158 DARYSY010000000
VERSION     DARYSY010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..860
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(60..626)
                     /locus_tag="TVR04_002021"
     CDS             complement(60..626)
                     /locus_tag="TVR04_002021"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270673.1"
                     /translation="MSAFKKNYINFGWLSDRAIYIDTITKEFYLTDIEKNSNGIMLLG
                     PVMSSISYAFLQVIGTYIGIVDDFVFRVIILGLLMVLSMIFGAGTVLFVRSKANFTPY
                     HLSDNHLAKVLKSANLQNWVIQICLIILSISSVCMSFLYLYKGRSTTVLMIGIFIAIS
                     TMLILDYSPLKKRRLIKKMKKSILNGIH"
     gene            complement(623..817)
                     /locus_tag="TVR04_002022"
     CDS             complement(623..817)
                     /locus_tag="TVR04_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270674.1"
                     /translation="MGIAIGVGTAVGGPFGFVLGVGLSMLFDATYDNKDSIVSDTNDF
                     VNDVGDVVSGFFGKLGSAFG"
BASE COUNT          297 a          176 c          103 g          284 t
ORIGIN      
        1 ttctgtatac tactcatcag ttatatctag aggacatatt tttaatgtct tttacctttc
       61 taatgaatcc catttaaaat ggacttcttc attttcttta tcaatcttct tttctttagt
      121 ggtgaatagt ccaatatcag catcgttgat attgctatga agataccaat catcagaaca
      181 gttgtgcttc ttcctttata tagataaaga aaactcatac agactgagct tattgacaag
      241 attattagac aaatttgtat tacccaattt tgtaaatttg ctgattttaa aacttttgct
      301 aaatggttat cagataaatg atatggagta aaatttgctt tagaacgtac aaataaaaca
      361 gtcccagctc caaatatcat agataatacc attaataagc ctaaaatgat cactctaaaa
      421 acgaagtcgt caacaatacc aatatatgta cctattacct gcaaaaatgc atagcttata
      481 cttgacatga ctggtcctag aagcattatt ccgttactgt ttttctcaat atctgtcaaa
      541 taaaattctt tagtaatagt atcaatataa atcgctctat ccgaaagcca accaaaattg
      601 atatagtttt tcttaaacgc actcatccaa aagcactccc tagttttcca aaaaagcctg
      661 aaacaacatc acctacatca ttgacaaaat catttgtatc cgatacaata ctgtctttat
      721 tatcataggt tgcatcaaaa agcattgata agccgacccc taacacaaac ccaaaagggc
      781 caccaacggc tgtaccaaca cctatagcta ttcccatatg tgctgctgtt attttgcaat
      841 actaccatat aaccctttct
//
LOCUS       DARYSY010000159          858 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYSY010000159 DARYSY010000000
VERSION     DARYSY010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>858
                     /locus_tag="TVR04_002023"
     CDS             <1..>858
                     /locus_tag="TVR04_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1270675.1"
                     /translation="AASAACIIMSGGFIGSSARVLAEQYYGWNDGTGMNSPFPVYVTP
                     ITEPNRKNAKIVYCFNKTMEWPQTWDEAAIKRPKDLPLYYDMEGTDSLFKQYASAALI
                     PKATKVLANILAKGYPNNSEFAGYFKLTPDSARKVTQIAIWTVTDNLSDYSQYNLKSE
                     EKRALSYLTENTNGDDYSNGIRLKLYIPQDSQTKKYQNLLGSTLITPERPKIPIPHNC
                     SCHKIYLEEKGKNGVWIITYIDENNNGMFDNGDKEIQRKLIKHGLDGSRGPKGEAGKA
                     GERGERGEKG"
BASE COUNT          317 a          150 c          165 g          226 t
ORIGIN      
        1 gcagcctcgg cggcctgcat cattatgtca ggcggcttta tcggcagctc cgccagagta
       61 ttagcagagc agtattatgg gtggaacgat gggacaggaa tgaattctcc attccctgta
      121 tatgttactc caattactga acctaataga aaaaatgcca aaattgttta ttgttttaac
      181 aagaccatgg aatggccaca aacttgggat gaagcagcca taaaaagacc aaaagactta
      241 cctctatact atgatatgga aggtactgat agcttattca agcaatacgc aagtgcagca
      301 cttatcccta aggctactaa agttttagct aatatattag ctaaaggtta tcctaataac
      361 agtgagtttg ctggttattt taaacttact cctgattctg ctagaaaagt tactcaaatt
      421 gcaatttgga cagttacaga taacttaagc gactattctc aatacaattt aaaatcggaa
      481 gaaaaacgcg cattaagcta cctaaccgaa aatacaaatg gtgacgatta tagcaatggt
      541 atcagattaa aactatatat tccacaagat agtcaaacta aaaaatacca aaaccttctt
      601 ggttctactt taataacacc agagcgacca aaaataccta tccctcataa ttgttcttgt
      661 cataaaattt acttagaaga aaaaggaaaa aatggggttt ggattatcac ttatatcgat
      721 gaaaacaata atggaatgtt cgataatgga gacaaagaaa ttcaaaggaa attaattaaa
      781 catggcttag acggttcacg tggacctaag ggtgaagctg gaaaagcagg tgaaagaggc
      841 gaacgtggag aaaaagga
//
LOCUS       DARYSY010000160          835 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.163, whole genome shotgun sequence.
ACCESSION   DARYSY010000160 DARYSY010000000
VERSION     DARYSY010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..835
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.163"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
BASE COUNT          276 a          158 c           96 g          305 t
ORIGIN      
        1 agaaaaaata ctgataaata tcttgataat gaattatata agtaattgga tctataaaaa
       61 aatgatagga tagtgtggaa acttttccac agcccctttc aaatatgagc tctcattttg
      121 cctttgccaa taaaaatcga gtaggactaa atataaccct ctcacacgat cgtacgtgcc
      181 attcgacata caagtagttc aatgcaaata ataatcaaaa cagctttaaa gtcctctctt
      241 tttgaggatt tctttgttta tatagtacaa tcctgttatg ttagttacaa cttaataata
      301 gtcgccaaac ccctaggaat gttttccatc tacagtggga catttaattt tcttttaaac
      361 ttttataatg aattctcgtg ttccctagcc ttccaactct cttttctttt tcagaatcta
      421 aatcctaaat attttagctt tgttggttta ataactttga atttcgttgc atttactttt
      481 aatcttaact tcttttctat acatttggtt actaaaacca ttactctgtt tgccactaca
      541 ctgtttgcta ctggtagtat actttcatct aaaaatcaaa ccaaccttaa tatcatattc
      601 ctgttcgtca agtcatgtcg ttcctctctt ccacatatct ccatgtgaat ttcaggatcg
      661 ctatgaaatt cgtcgacaac tacgctattt aggaactttc accccagtat tggaacttgc
      721 ccgttataca aaaaattttg atactaataa tttagttaat atcaaaattt taaataccat
      781 tatattttaa aaaaacaatt aatactaaac ttataaaaat agcactaata aaagc
//
LOCUS       DARYSY010000161          828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.164, whole genome shotgun sequence.
ACCESSION   DARYSY010000161 DARYSY010000000
VERSION     DARYSY010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.164"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..750
                     /locus_tag="TVR04_002024"
     CDS             <1..750
                     /locus_tag="TVR04_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002839222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEL1270676.1"
                     /translation="DLHELFSYLTARYGEIKSAEAIQKELKKLFNQMYEKKYTSKSIT
                     KYDSEGNPYTYRILTLTIKKKSIDEIAREEFANYETNMAHYLALLDSQGNMSGYFGSS
                     YGNLGEIIDNPNFGNPGLAFDSETAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCW
                     SFTKSGVKRMPRTTAWLIYKNYCNPISPSEAKPGDIIFFKGTYNSGTPISHVGIYAGN
                     GMMLHAGDPIQYASINSRYWKNHFYSFGRPK"
BASE COUNT          327 a          114 c          158 g          229 t
ORIGIN      
        1 gatctacacg agctttttag ctatttaaca gcaagatatg gagagattaa gtcagctgaa
       61 gcgatacaaa aggaattaaa aaaactattt aatcaaatgt atgagaaaaa atatacttca
      121 aagtctatta caaaatatga cagtgaagga aatccatata cctatagaat tctaacatta
      181 actataaaaa agaaaagtat tgatgaaata gcaagagaag aatttgcaaa ctatgaaaca
      241 aatatggctc attatttagc attacttgat agtcagggaa atatgagtgg atattttgga
      301 tcaagctatg ggaacttggg agagattata gacaatccaa actttggaaa tcccggtctt
      361 gcttttgatt ctgaaactgc caaagcctta tttaatgaag cagaaaaaca tataggcaaa
      421 agatatgtgt ttggagcaag tggaccatct aactttgact gttcaggttt tgtatgttgg
      481 tcatttacaa agtctggtgt aaagagaatg ccaagaacta cagcttggct tatttataaa
      541 aactattgta atccaatatc tccaagcgag gcaaaacctg gggatattat tttctttaaa
      601 ggcacatata attcgggtac gccaatttct cacgtaggga tatatgccgg aaatggaatg
      661 atgctccatg caggagatcc tatccaatat gccagtataa actcaaggta ttggaaaaat
      721 cacttttatt cctttggtag accaaaataa gggggaagga gtaaaaatct atgaataaaa
      781 aattaattag aaacatagaa aaacagaaga atttaagaaa gaaaaaag
//
LOCUS       DARYSY010000162          807 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYSY010000162 DARYSY010000000
VERSION     DARYSY010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            19..807
                     /locus_tag="TVR04_002025"
                     /pseudo
     CDS             19..807
                     /locus_tag="TVR04_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_088186184.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          290 a          129 c          184 g          204 t
ORIGIN      
        1 caatggggtg ctttttatat gaaattaagt tacgatgata aattaagaat atatgaacta
       61 agaaaaaatg ggatgtcttg ttcccgcatt ggtcaacagt atgatattca ggtttctaat
      121 ctcaaataca tggtaaagct tatggacaga tatggagttg agattgttag aaagggtaaa
      181 aataagtatt atcctccaga attaaaacaa gaaataattg ataaagttct tcttgaaggt
      241 cagtctcaac tgtctgtctc tcttgagtat gctctcccaa atgctggtat gcttcccaat
      301 tggatagcgc aatacaagaa aaacgggtat actattcttg agaaacaaag agggagacca
      361 acgaagatgg gccgtaaacc aaagaaaact tgggaagaaa tgacagagct agagcgcctt
      421 caggaagagc tagaatacct tagaacggag aatgcttatc taaaaaagtt gagggagctt
      481 cgtttacagg acgaagccag agagtgagaa aggcagaaac aattagagag atggtccaag
      541 aaggattccg attaaacctc ctacttgaga tcgctaagat ggctcgttca acctattatt
      601 atcaagtcaa gcaattggat aagtcagata aagatgaagc aatcaactct gaaatcaaag
      661 cgatttatga ggagcataag ggaaactatg gttaccgtcg catccattta gaactcaaga
      721 atcgtgggtt tgtcgtcaat cacaagaaag tgcaacgctt gatgaaagag atgagattag
      781 ctgctcgaat tcgtcgtaaa cgcaggt
//
LOCUS       DARYSY010000163          805 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYSY010000163 DARYSY010000000
VERSION     DARYSY010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            34..>805
                     /locus_tag="TVR04_002026"
     CDS             34..>805
                     /locus_tag="TVR04_002026"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1270677.1"
                     /translation="MFAILIYLSGVSIILTGVELLFILLLFTLLINLQPKIQSTSDNE
                     LHQASLAQSIQLDAIVSINNIKLGGYKEAYKEDWASKYKKSLDYTAERMNIQQSWIGT
                     ILGMVSAFVPLVILSMALFQFSLGRLSLGEAIATQTVTSLLYNYANSIFTTFSNFSVL
                     NRYVDLAEDIYEYPIENSGDIKYQIFKDELVLDNVSFSYSGNNIYALRSINLKIKKGE
                     TIALVGESGSGKSTLGKIISSLFMPTIGTIYLDGISYKD"
BASE COUNT          262 a          118 c          143 g          282 t
ORIGIN      
        1 tcattgatcc aattattttt ggacatcatt agcttgtttg caattttaat ttatttatct
       61 ggcgtgtcaa ttattttaac tggagttgag ttgcttttta tattgttgct ttttacatta
      121 ttaattaact tacagcctaa aattcaatca acaagtgata atgaacttca ccaggcttca
      181 ttagctcaaa gtatacaact agatgcaatt gtgtccatta acaatatcaa gctaggagga
      241 tataaggaag cttataagga agattgggca agcaagtata aaaaatcttt ggactacaca
      301 gccgaaagaa tgaatattca acaatcttgg ataggcacca ttttagggat ggtgagtgcc
      361 tttgtcccac ttgttatatt gtcgatggct ttgtttcaat tttctttggg gcgactgagt
      421 ttaggcgagg ccattgcgac acagacggtt acatcactac tttataatta cgccaattca
      481 atttttacta ctttctcaaa tttttctgta ttaaatcgtt atgtagattt agcagaagac
      541 atatatgaat atcctattga aaattctgga gatataaaat atcaaatttt taaagacgag
      601 cttgttttag ataatgtaag ctttagttat agcgggaata atatatatgc tttaaggagt
      661 attaacttga aaataaaaaa aggagaaact atcgccttag ttggagaatc cggttccggg
      721 aaatctactt taggcaaaat aatcagtagt ctatttatgc ctaccatagg aacaatttat
      781 cttgacggta tttcatataa ggatt
//
LOCUS       DARYSY010000164          788 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYSY010000164 DARYSY010000000
VERSION     DARYSY010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>788
                     /locus_tag="TVR04_002027"
     CDS             <1..>788
                     /locus_tag="TVR04_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004837868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1270678.1"
                     /translation="IKTSKHNRARNGYFIGSVPPYGYKIKKFKEGQRLVIDENVRFIV
                     EEMFDLTLQGKSQYEVAKHFNEKGYAPGMIYYKTGRVYRQDDDPEWNKGTISKMLTNP
                     AYTGTLVQGVKQQNLAKGIKQHFVDESQYIICENAHEPIISKEVHERILQERRERKKN
                     HVFSSPMHNFENRDYENRFKGLVINNNTGKELNRRTRIYGKNKDRLYYSFQNERFSGS
                     IKPEKSVFIMERDLDQAISDKISEFIMKTTSKTKFVNRIKARFN"
BASE COUNT          322 a           95 c          151 g          220 t
ORIGIN      
        1 gataaaaacc tcaaaacaca atagggcaag aaacggatat tttattggtt ctgttccacc
       61 ttatgggtac aagattaaaa aatttaaaga aggtcaaaga cttgtaattg atgaaaatgt
      121 tagatttata gttgaagaga tgtttgattt aactcttcaa ggtaaaagcc aatatgaagt
      181 cgcaaagcat tttaatgaaa agggatatgc tcctggaatg atttactata aaactgggag
      241 agtttacaga caagatgatg atcctgaatg gaataaaggg acaatttcta aaatgcttac
      301 aaacccagct tatacgggga ctttagtaca aggagttaag caacaaaatc tagcaaaagg
      361 aattaaacaa cattttgtag atgaaagtca gtatataatt tgtgagaatg cacatgaacc
      421 aatcatttct aaggaagttc acgaaagaat attacaagaa agacgagaga gaaagaaaaa
      481 tcatgttttc agttcgccga tgcacaattt tgaaaatagg gactatgaaa acagatttaa
      541 aggtcttgta atcaataata atactggcaa agaacttaat agaagaactc gtatctatgg
      601 taaaaataaa gatagacttt actattcatt tcagaatgag agatttagtg gaagtataaa
      661 acccgaaaaa tcagtattca ttatggaaag ggatttggat caggctatta gtgataagat
      721 ttctgagttt attatgaaga caactagcaa gacaaaattt gttaatcgaa ttaaagctag
      781 atttaata
//
LOCUS       DARYSY010000165          761 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYSY010000165 DARYSY010000000
VERSION     DARYSY010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            287..490
                     /locus_tag="TVR04_002028"
     CDS             287..490
                     /locus_tag="TVR04_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270679.1"
                     /translation="MRYYKSIRQNKGLSQAIIGEVISRQSLISFEKGESTPRYETMMF
                     LLRQIDMTFGDVEGSYTEIERVL"
     gene            complement(594..>761)
                     /locus_tag="TVR04_002029"
     CDS             complement(594..>761)
                     /locus_tag="TVR04_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1270680.1"
                     /translation="FFGHFKTECYDLKDYKTFEELVYDIDDYIYFYNNERFQEKHNGL
                     APLEVRNKAVA"
BASE COUNT          270 a          132 c          142 g          217 t
ORIGIN      
        1 aaacataagc ttaattcata tcagaatctt tttacaatac aactatacca tatcataaaa
       61 ggtttttggg acagagctta agttttttgc agctcattag cagaattttc aagggcaaaa
      121 aaagatatta aaaagacaaa gcttaaaaaa taacatttat ttcctcatca aatcttcctt
      181 tatggcgttt agatgatgct attgtcataa aaagtgcagg gaataatccg tttttctaca
      241 ctatttgcta gtgatttcaa aggaggcaag gttaggagaa agaagcctgc gctattacaa
      301 gagcatacga caaaataagg gattatcaca ggcaatcatt ggagaagtca tcagcagaca
      361 aagcttgatt agctttgaaa aaggggaaag cactcctcgc tatgaaacta tgatgtttct
      421 attgagacaa attgacatga cttttgggga cgttgaaggt agctacactg agattgagag
      481 agtgttatga ttgcggttac cagccaaggc ttctcgtaaa aaaatacaaa aaaattagct
      541 tcctctgata ggtgaactgc tccctgtcaa gtagacaatg aaataataaa agattaagca
      601 acggccttgt tcctcacttc aagaggggca aggccgttgt gcttctcttg aaatcgttcg
      661 ttattgtaaa aatagatata gtcatcaata tcataaacta actcctcaaa cgtcttgtaa
      721 tccttcaagt cataacactc cgtcttaaag tgaccaaaga a
//
LOCUS       DARYSY010000166          759 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYSY010000166 DARYSY010000000
VERSION     DARYSY010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            234..759
                     /locus_tag="TVR04_002030"
                     /pseudo
     CDS             234..759
                     /locus_tag="TVR04_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          263 a          108 c          142 g          246 t
ORIGIN      
        1 agttgacttg ttagtttaaa ctttttataa taaatcaaat gagaagataa tatgaggctt
       61 agcctaagct gctgagctta tctgataatc attcttctta gcactgagat aaccccctct
      121 atcaatcaat tggagaatct atgatacgtt ttaataatgt ttccaaaacc tttggtcaca
      181 ccaaggtgct gcaggagcaa agttttcaaa tacagaatcg cgaatttttt gtgctggtcg
      241 gtccaagtgg ctctggaaaa acaacacttt gtaatttgat agctagattt tgggatgtag
      301 attctggaga aatattgatt gatgataata acataaaaga ttttaggtat gacaatctgt
      361 tatctaattt cacttttgtt tttcaagacg tctatttatt tgatgacact ataaaaaaca
      421 acattaagtt cggaaatcca gaagctagtg atgaggaagt tattaatgtt gctaagcaag
      481 cacagtgtca tgaatttatt atgaagttgt cagatggtta tgacacagtt ttacaagagg
      541 gtggttcaaa tttatctgga ggagagcgtc agagaatatc tatagcaaga gctatgctaa
      601 aaccaagcag aattgttatt cttgacgaag ctacttcaag tgtagatcca gaaaatgaac
      661 aacaacttat aactgcttta aacaatttgt taaaagataa aactgtaatt gtgattgcac
      721 ataaacttga aactattaaa aatgctgatc aaattgttg
//
LOCUS       DARYSY010000167          738 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYSY010000167 DARYSY010000000
VERSION     DARYSY010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..399
                     /locus_tag="TVR04_002031"
     CDS             <1..399
                     /locus_tag="TVR04_002031"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1270681.1"
                     /translation="TLNIDGNIATDIEIKDLKSKDGRDFKVASFSIAENDKGGDAKFI
                     SCYAYNDKINQVKNLKKGDFVHLFGKEKKSMGKDNKEYTSLKVYSAKLLKAKEHTKAK
                     ASTLGKLKEFKTKGDMKVDEKKKKDNSIER"
BASE COUNT          315 a           84 c          155 g          184 t
ORIGIN      
        1 acattaaata tagatggaaa tatagcaact gatatagaaa ttaaagattt aaaatcaaaa
       61 gatgggaggg actttaaagt agcctccttt tctattgctg aaaatgacaa gggaggagat
      121 gcaaaattca tcagctgcta cgcctataat gataaaatca atcaagtaaa aaatttgaaa
      181 aaaggagatt ttgtacacct atttggcaaa gaaaagaaaa gtatgggaaa ggataataag
      241 gaatacacaa gtctaaaagt atactctgca aagttattaa aagctaaaga gcatactaaa
      301 gcaaaagcat caacactagg gaaattaaag gaatttaaga ctaaagggga tatgaaagtg
      361 gatgaaaaga agaaaaagga taatagcata gaaaggtaaa agattatagg gggcaggttt
      421 tagtctgctt attgtattgt atgatggggc aagttccaat actggggtga aagtccctaa
      481 acagcgtatt tgtcgacgaa ttccatagca atcctgaaat ttcacatgga gatatgtgga
      541 agagaggaac gacctgactt gatgaacatg aatatgatat taaggttggt tagatatgta
      601 gattacagta tactaacagt agcaaacagt gtagtggcaa acagagtaat ggttttagta
      661 accaaatgta tagaaaagaa gttaggatta aaataaatgc aacaaaattc aaatttatta
      721 aaccaacaaa gctaaaat
//
LOCUS       DARYSY010000168          726 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYSY010000168 DARYSY010000000
VERSION     DARYSY010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            108..431
                     /locus_tag="TVR04_002032"
     CDS             108..431
                     /locus_tag="TVR04_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270682.1"
                     /translation="MKTLDRQKQEILREIYRLGYDTLRFSIFSKERPGEWEVVIEYDD
                     TSGVYLVYGTMDRSSYHGKTAYRKFNAAKEGFMTFLEDIVMINKYYVEEGMPVNYDSP
                     LWSNN"
BASE COUNT          257 a           93 c          157 g          219 t
ORIGIN      
        1 aaggaatgat tgatcttgtc tttggttctg gtggaggtat ccaaataaag ctaggaactt
       61 ctgtaagttg gtatgaaaaa ttgggtttaa ttaaggagat aaagtagatg aaaactttag
      121 atcgtcaaaa acaagaaata ctacgagaaa tataccgttt gggatatgat acattaagat
      181 tttctatttt ttccaaagag agaccaggag aatgggaagt agttattgaa tatgatgata
      241 ctagtggagt gtatcttgtt tatggaacca tggatagaag tagctatcat ggaaagacag
      301 cgtatcgtaa atttaatgct gcaaaggagg gcttcatgac atttttagaa gatattgtga
      361 tgataaataa atactatgtg gaagagggca tgcctgtaaa ttacgattct cctttgtggt
      421 caaacaatta atacaaaaaa aggataacac acatggcacg cagtcaatta gagtgggaag
      481 ataaatgaaa taatggtcct aggaaatgtc ccaactggaa actatcttat gaactctttt
      541 atggaaaagt gttgcacttc attggataat gtaccacctg aaaagtattg gtagagttgg
      601 tagaaagtaa aaaagcaccg attcggtgct ccccttttca ggttgattac ggacaaagcc
      661 ttattttaac tttgctatgc tgtattgaat agttccatag gactatttta taataatcct
      721 aaaaaa
//
LOCUS       DARYSY010000169          713 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.172, whole genome shotgun sequence.
ACCESSION   DARYSY010000169 DARYSY010000000
VERSION     DARYSY010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.172"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>713
                     /locus_tag="TVR04_002033"
     CDS             <1..>713
                     /locus_tag="TVR04_002033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270683.1"
                     /translation="HHYKLSTIYNDINDLEIERKLYRSNLKDIAPIQSFITQDEIAES
                     LKRGSGFSDGKKRIYEFFTGKHDLKEQADFLKNEYGVGGSSHALSAARESGEWHDAKG
                     IKYTKGNAKEIQLSWSNVARKINDLIKKNRYIDEESFQENREKKADQEINKTEKESQE
                     YINYQDDLPPTDNDVYIEKTNNSSIYYYQGQSVASIGDNGKLIIYDEFIPNFLKEELY
                     SIGFEKQLDIPLDQLDDGI"
BASE COUNT          308 a           79 c          131 g          195 t
ORIGIN      
        1 ttcatcatta taaattatct acaatctata atgacatcaa tgatctagaa atagaaagaa
       61 aattatatag gtcgaattta aaggatattg cacctattca gagttttata acacaagatg
      121 aaatagctga aagcctaaaa agaggtagtg ggttttctga tggaaagaaa agaatatatg
      181 aattttttac tgggaagcat gatttaaaag aacaagcaga tttcttgaaa aatgaatatg
      241 gagtaggtgg aagttctcat gcactatctg ctgcgagaga aagtggtgag tggcacgatg
      301 cgaagggaat aaaatatact aaaggtaatg caaaagaaat acaactatcc tggtccaatg
      361 ttgcaagaaa aattaatgac cttattaaaa agaatagata tatagatgaa gaaagttttc
      421 aagaaaatag ggagaaaaaa gcagatcagg aaataaataa aacagaaaaa gaaagccagg
      481 agtatataaa ttatcaagat gatttacctc caactgataa tgatgtatat atagaaaaaa
      541 caaataatag ttctatatat tattatcaag gacagtctgt agcaagtata ggtgataatg
      601 gaaaacttat catttatgat gaatttatac caaacttttt aaaagaagaa ctatattcca
      661 taggctttga aaaacaatta gatataccct tagaccagtt agacgatgga att
//
LOCUS       DARYSY010000170          704 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.173, whole genome shotgun sequence.
ACCESSION   DARYSY010000170 DARYSY010000000
VERSION     DARYSY010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.173"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            69..>704
                     /locus_tag="TVR04_002034"
     CDS             69..>704
                     /locus_tag="TVR04_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
                     /protein_id="HEL1270684.1"
                     /translation="MEQSHVITQLLGIKDPHITFSKEIHDMKTHKELKAVLDYDAPPC
                     PNCQSQMGKYDFQRESKVPFLDCAGYKTLIRLKKRRFKCQFCGKITVAETSLVPKNHQ
                     IPTIVKQKVAQLLIEKVSMTAIADRLSISTSTVMRKLNEFTFKSHLTYLPEHMSWDEY
                     AFKKGKMSFIAQDFDTNNIIAILDGRTKAVIRNHFLRYPRQVRNDVKLITMD"
BASE COUNT          225 a          180 c          126 g          173 t
ORIGIN      
        1 tgagtatcaa aaaagtccca tatgacctat aatgaaaagc gactaaacta tcatttagaa
       61 agactcatat ggaacaatca catgttatca cacaactact gggaattaaa gaccctcata
      121 tcacattctc caaagaaata cacgacatga aaactcataa ggaattgaaa gctgtccttg
      181 actacgatgc cccaccttgc cctaactgcc aaagtcagat gggcaagtac gacttccaac
      241 gggaatccaa ggtccctttt ctcgattgcg caggctacaa gactttgatt cgcctcaaaa
      301 agcgccgttt caaatgtcag ttttgcggaa aaattactgt cgctgagact tctctagtcc
      361 ctaaaaacca tcaaatacca accatcgtca aacagaaggt ggcccagctt ctcatcgaga
      421 aagtctccat gaccgctatc gctgatagac tatccatctc cacctcaacc gtcatgcgaa
      481 agctcaacga gttcacgttc aagtctcatt tgacttattt acccgaacat atgtcctggg
      541 atgaatatgc ctttaagaag ggcaagatga gctttattgc tcaggacttt gacaccaaca
      601 acatcatcgc tattttggat ggacggacga aagctgtcat tcgcaaccac ttcctgagat
      661 atcctcggca ggtcagaaac gacgttaaac tcatcaccat ggat
//
LOCUS       DARYSY010000171          700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.174, whole genome shotgun sequence.
ACCESSION   DARYSY010000171 DARYSY010000000
VERSION     DARYSY010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.174"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>700
                     /locus_tag="TVR04_002035"
     CDS             <1..>700
                     /locus_tag="TVR04_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1270685.1"
                     /translation="TKLIEMGVPENEIEFIHKAKNNMEKDAIFDKVRKGEIRVLLGST
                     QKMGAGTNAQDKLIAIHDLDIPWRPADLSQRAGRIVRQGNENKEVHIFRYVTENTFDA
                     YLFQTLENKQKYISQIMTSKTPVRVAEDVDEATLNYAEIKALATGNPLIKEKMDLDVE
                     VSKLKMLESNFKSNLYKLEDKVVKFYPKEIERLKERIENLKEDIKNVEPYREVDKNLK
                     EDNKFTSLIIDGKKY"
BASE COUNT          298 a           94 c          131 g          177 t
ORIGIN      
        1 aacaaaactt atagaaatgg gagtacctga aaatgaaata gaatttattc ataaggcaaa
       61 aaacaatatg gaaaaagacg ctatctttga taaggtaaga aagggagaaa taagagtctt
      121 acttggttca acacagaaaa tgggagcagg tactaatgcc caagacaaac taattgcaat
      181 tcacgatctt gatataccat ggagacctgc tgatctttct caaagagcag gcaggattgt
      241 gaggcaggga aatgagaata aggaagtcca tatatttaga tatgtaacag aaaatacttt
      301 tgatgcctac ctattccaaa ccttagagaa taaacaaaaa tatatttccc aaattatgac
      361 ttcaaagact cctgtaagag ttgcagaaga tgtagacgaa gccacattaa actatgccga
      421 aatcaaagct cttgcaacag gaaatccatt aataaaggag aagatggacc ttgatgttga
      481 agtttctaaa cttaaaatgc tagagtccaa ttttaaatca aatctttaca agctggaaga
      541 taaagtagtt aaattttatc caaaggaaat agaaagatta aaagaaagga tagagaactt
      601 aaaggaagat attaaaaatg ttgagcctta tagagaagta gataaaaatt taaaagaaga
      661 taataaattt acctctctaa ttattgacgg aaagaagtat
//
LOCUS       DARYSY010000172          680 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.175, whole genome shotgun sequence.
ACCESSION   DARYSY010000172 DARYSY010000000
VERSION     DARYSY010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.175"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            190..>680
                     /locus_tag="TVR04_002036"
     CDS             190..>680
                     /locus_tag="TVR04_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009537685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1270686.1"
                     /translation="MKQDMKEQLLTKRPIDLLFQLSVPAVIGMIVIGLYPLMDGIFAG
                     NIIGQTAMTACGVAMPLTFFNSGVSTLIGVGSASVLSRAIGKGDKKTVDKIMGNLIFW
                     VILFSSIITIGGILLAPHFLDMVGASGEIKEYGIRYLRVIFIGSLFVNFTQSANMVMR
                     GEG"
BASE COUNT          239 a           78 c          134 g          229 t
ORIGIN      
        1 aactattttt attatcacac atgatccgga attagtagaa tgttgttgtg attattttat
       61 gtttatggag aatggaaaag tcaaatggca tggtattaaa gatgaaaaga atatggaaaa
      121 aattagagaa ttcttcgatc aaacttaaaa tttggctaaa aaatatggat gaaaaaagga
      181 ggtaatttta tgaaacaaga tatgaaagaa caattattaa caaaaagacc catagattta
      241 ctttttcaat tatctgtccc tgctgtaata ggaatgatag taataggtct ttatccacta
      301 atggatggaa tttttgcagg aaatattata ggacaaacag caatgacagc ttgtggtgta
      361 gctatgccac ttacattttt caatagtggt gtatctacac ttattggtgt aggttcagca
      421 tcggttttat caagagctat aggaaagggc gacaaaaaaa cagttgataa aattatgggg
      481 aatttaatct tttgggttat tctattctca tcaattatta caataggcgg aattttactt
      541 gcaccacatt ttttagatat ggttggagca agtggtgaaa ttaaagaata tggtatcaga
      601 tatttacgcg tgattttcat tggttcttta tttgtaaact ttactcaatc agcaaacatg
      661 gttatgcgtg gagaaggatt
//
LOCUS       DARYSY010000173          671 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.176, whole genome shotgun sequence.
ACCESSION   DARYSY010000173 DARYSY010000000
VERSION     DARYSY010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.176"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            202..513
                     /locus_tag="TVR04_002037"
     CDS             202..513
                     /locus_tag="TVR04_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1270687.1"
                     /translation="MKQEMININANLVAEPTFSNFEKDGETVEVANFTLVKKYGKGKE
                     YINCAAYGEKADKAKSFEKGDLIHVFGYFKKREKEGKIYKNFVVKSYNKIEKKEENEE
                     E"
     gene            517..>671
                     /locus_tag="TVR04_002038"
     CDS             517..>671
                     /locus_tag="TVR04_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270688.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQFMA"
BASE COUNT          275 a           86 c          147 g          163 t
ORIGIN      
        1 actagtattt caagtacttt tcactaatat atacacgaca aaatgctaat tcccttaaat
       61 atgttaaaga caataaagga gataagatga taaggatcag aagtcccact aagaaaaaac
      121 taaatagaaa gagtatcagc gattggaaaa gaaatactcc agtcgctttt ttattgaatt
      181 gaaaaggaga aatttaaaaa gatgaaacaa gaaatgatta acatcaacgc caacttagtg
      241 gcggaaccta ctttctcaaa ctttgaaaaa gacggagaaa cggtagaagt tgcaaacttc
      301 acgcttgtaa agaagtacgg aaaaggcaag gagtacatta actgtgcagc ctatggagaa
      361 aaagcggata aagcaaaatc ttttgaaaaa ggcgatttga ttcatgtatt cggctacttt
      421 aagaagcgtg aaaaagaggg aaagatttac aaaaattttg tagtgaagtc atacaacaag
      481 attgaaaaga aagaagaaaa tgaggaggaa taaattatgg aatttttcgc acaggcagta
      541 aatgtattaa aaattttggt tatggcagta ggagcaggac ttggagcatg gggtgttatt
      601 aacctgatgg aaggatatgg gaatgacaat cccggagcaa aatctcaggg gattaagcaa
      661 tttatggcaa a
//
LOCUS       DARYSY010000174          661 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.177, whole genome shotgun sequence.
ACCESSION   DARYSY010000174 DARYSY010000000
VERSION     DARYSY010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.177"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            39..>661
                     /locus_tag="TVR04_002039"
     CDS             39..>661
                     /locus_tag="TVR04_002039"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1270689.1"
                     /translation="MKKTMKKMLAASAACIIMSGGFIGSSARVLAEEYYGWNDGTGNG
                     KPSHLYVTLKQGNTQTETRNLDSKNIVYCFNRDLAWPENWEQGKALSTVQSDLRFRLP
                     IYDRVDGTDILFKEISKNFRKEVKSPTAALVAVLSNGYPTVQNINNIQLDANSSLKVT
                     QLAIWYFSDGAGQPNTYGYPLSENEQKAYDFLVKIGDKNGAVEVNEG"
BASE COUNT          242 a          101 c          140 g          178 t
ORIGIN      
        1 aggaatgatt aattctaaac ttaaaggaga gagaaacaat gaaaaaaaca atgaagaaga
       61 tgctagcagc ctcggcggcc tgtatcatta tgtcaggcgg ctttatcggc agctccgcca
      121 gagtattagc ggaggaatat tatgggtgga atgatggaac tgggaatgga aaaccttccc
      181 atttgtatgt aacattaaaa caaggtaata ctcaaactga gacaagaaat ctagattcta
      241 aaaatattgt ttattgtttt aatagagact tagcttggcc agaaaattgg gaacagggta
      301 aagcgttatc cacagtccaa tctgatcttc gatttaggtt acctatttac gatagagttg
      361 atggtacaga tattttattt aaagagatat cgaaaaattt tagaaaagaa gtaaaatcac
      421 cgacagcagc actagtagca gtcttgagca atggctatcc aactgtccaa aatattaata
      481 atattcaact tgacgctaat tcaagtctaa aagtaacaca acttgctatt tggtatttca
      541 gtgacggggc aggtcagcct aatacatatg gctatccact aagtgagaac gaacaaaaag
      601 cttatgactt tttggtaaaa atcggagata aaaatggtgc agttgaagtt aacgaaggaa
      661 t
//
LOCUS       DARYSY010000175          640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.178, whole genome shotgun sequence.
ACCESSION   DARYSY010000175 DARYSY010000000
VERSION     DARYSY010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.178"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>640
                     /locus_tag="TVR04_002040"
     CDS             <1..>640
                     /locus_tag="TVR04_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009537685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1270690.1"
                     /translation="GVGSSAMMMQILFMIQQTMLYKMSFKYGGDTNAILMAATLRIYA
                     FSFIPLWGMSQGLQPVVGTNFGAKKYDRVKEAMKVFSIGGLVLASIFWIPALAFSKNI
                     LSLFGVEESIITQGIGNFRLFYSIFILYGVMVMTITFFQSIGNAKKAGIIVMLRQLFL
                     FVPAMIILPMIFGVKAVWFAEPLVDLIMIIAGVVMMFGELNRMDKISLKNSSN"
BASE COUNT          218 a           82 c          124 g          216 t
ORIGIN      
        1 ggcgtagggt catctgctat gatgatgcaa attttattta tgattcaaca aacaatgcta
       61 tataaaatgt catttaaata tggcggagat acaaatgcta tcttgatggc agcaacactt
      121 agaatatatg ccttttcatt cattccactt tggggaatga gtcaaggttt acaacctgta
      181 gttggtacaa attttggagc gaaaaaatac gacagagtaa aagaagctat gaaagtattt
      241 tctatcggag gattagttct tgcatcaata ttttggatac cagcattagc attttcaaag
      301 aatatacttt ccttatttgg agtagaagaa agtattataa ctcagggaat agggaacttt
      361 agactatttt attctatctt tatcctatat ggagtaatgg taatgactat aacattcttc
      421 caatcaatag gaaatgctaa aaaagccggc ataatagtaa tgctaagaca gttattttta
      481 ttcgtgcctg ccatgattat tttaccaatg atatttggag ttaaagcagt atggtttgct
      541 gaaccccttg tagatttaat tatgataata gctggtgtag taatgatgtt tggggaatta
      601 aataggatgg ataaaattag tttgaaaaat tcaagtaatg
//
LOCUS       DARYSY010000176          551 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.179, whole genome shotgun sequence.
ACCESSION   DARYSY010000176 DARYSY010000000
VERSION     DARYSY010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.179"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>551
                     /locus_tag="TVR04_002041"
     CDS             <1..>551
                     /locus_tag="TVR04_002041"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270691.1"
                     /translation="ELIKIRNSLAHGRIAQNMDIMEYPLTPFYNITKTEGHLVTPIGI
                     LTAVSISKFIGIHIWEYEWNEIKRLLEPRPDLVEDFLEGRLDVDINNENEYNLTWYSL
                     FRYYLNCKDRWKKVIETRMKLELSKRQLENLDLPNLYEIAVILIDTEDKQLFKMLSCV
                     ITKIVEGNKFRWSNYRDIFLYLE"
BASE COUNT          203 a           67 c          108 g          173 t
ORIGIN      
        1 acgagctaat taagattaga aatagtctgg ctcacggtag aattgctcaa aatatggata
       61 taatggagta tcctttgaca ccgttttata atattactaa aacagaaggg catttagtta
      121 ctccaattgg tattttaacg gcagtatcaa tttctaaatt tattggtatt cacatttggg
      181 aatatgaatg gaatgaaata aagcggttgt tagaaccgag acccgatttg gtagaagact
      241 tcttagaagg tcgactcgat gttgatatta acaacgagaa tgagtacaat ttgacctggt
      301 actcactgtt tcgatattac ttaaactgta aagatagatg gaagaaagtt attgaaacaa
      361 gaatgaaatt agagttgagt aaaagacagc ttgaaaatct agacttacct aatctttatg
      421 aaatagctgt aattttaatt gatactgaag ataaacaact gttcaaaatg ctgagctgtg
      481 ttatcacaaa aattgttgaa ggaaataaat tcagatggag taactataga gatatatttc
      541 tatatttgga g
//
LOCUS       DARYSY010000177          551 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.180, whole genome shotgun sequence.
ACCESSION   DARYSY010000177 DARYSY010000000
VERSION     DARYSY010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.180"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            61..462
                     /locus_tag="TVR04_002042"
     CDS             61..462
                     /locus_tag="TVR04_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1270692.1"
                     /translation="MAFADRLKEFREKEKLSQADFAKMIGISTRTLVHYEDGERYPRD
                     VEVYKKIAEVMDCDYNYLLEESDEFLNRVYNMGGKRELEKARALTEGLSSLFAGGEIS
                     DEDKDAAFEAITRAYWEAKRENKKYGRKKKD"
     gene            471..>551
                     /locus_tag="TVR04_002043"
     CDS             471..>551
                     /locus_tag="TVR04_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HEL1270693.1"
                     /translation="MSMNRYIYDKVNRLIKKYKTRDPIELI"
BASE COUNT          216 a           61 c          120 g          154 t
ORIGIN      
        1 tcaagcacta ttgttcgtat taaaagttat aaatgcacat tagtacagga ggttaaagtt
       61 atggcttttg cggatagatt aaaggaattt cgtgaaaaag aaaagttaag tcaagcagat
      121 tttgcaaaga tgataggaat aagtacaaga actcttgtac attatgaaga cggagaaaga
      181 tacccaagag atgtcgaggt ttacaaaaaa atagctgaag ttatggactg cgattacaat
      241 tatcttctag aagaaagtga cgagttttta aatcgagttt ataacatggg tggtaaaaga
      301 gaattagaaa aagctagagc attaacagaa ggtctaagct ctttatttgc tggtggagaa
      361 atttctgacg aagataaaga tgctgctttt gaagctatta ctcgtgctta ttgggaggct
      421 aaaagagaaa acaagaaata cggtcgtaag aaaaaagatt aggtgatttt atgagcatga
      481 atcgctatat atatgataag gttaatcgac ttataaaaaa atataagaca cgagatccta
      541 tcgaattaat a
//
LOCUS       DARYSY010000178          543 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.181, whole genome shotgun sequence.
ACCESSION   DARYSY010000178 DARYSY010000000
VERSION     DARYSY010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.181"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>543
                     /locus_tag="TVR04_002044"
     CDS             <1..>543
                     /locus_tag="TVR04_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270694.1"
                     /translation="LDMGKSEDISQDNPLLEEVKEELIDFLNREYDEENRLEDFDTIF
                     PDLTDIGIAYTTTPDEKHEIQVSLDLINYKMNTYVDKNLIDSFQYTYDPLDASDLKEL
                     VQIKTSIGFWDFSELVSVNEEKLREVMGLEIDDDGNFYDPLSKDMDLDGIIDRNDADF
                     RDSKVQEIGDFERKEKTSIMD"
BASE COUNT          226 a           58 c          110 g          149 t
ORIGIN      
        1 ctagatatgg gaaaaagtga agatataagc caagataatc cattactaga agaagtaaag
       61 gaagaattga tagacttcct taacagagaa tatgatgaag aaaacaggtt agaggacttt
      121 gatactatat ttcctgactt aacagatata ggaatagctt atacaactac accagatgaa
      181 aaacatgaaa tacaagtaag tttagattta ataaattaca agatgaacac ctatgtagat
      241 aagaacttaa ttgacagttt tcaatacacc tatgatccct tagatgcaag tgatttaaaa
      301 gagttagtac agataaagac atctattgga ttttgggact ttagtgagct tgtatcagta
      361 aatgaagaaa aattgagaga agtaatggga cttgagatag atgatgatgg caacttctat
      421 gatccactat ctaaagatat ggatttagac ggaataatag atagaaatga tgctgatttt
      481 agagatagta aagtgcagga aataggagat tttgaaagga aagaaaaaac atctattatg
      541 gat
//
LOCUS       DARYSY010000179          511 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.182, whole genome shotgun sequence.
ACCESSION   DARYSY010000179 DARYSY010000000
VERSION     DARYSY010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.182"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..300)
                     /locus_tag="TVR04_002045"
     CDS             complement(<1..300)
                     /locus_tag="TVR04_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1270695.1"
                     /translation="MTKEYYLYVGGQKIKVSEQIYKVYWQEREHEKYLEQVDKKNHLL
                     FFSSLNHDGNFEDNLEDKNVDVEKVVATQMMIEALRNAMSKLNKDEREIIERLYFN"
BASE COUNT          144 a           90 c           65 g          212 t
ORIGIN      
        1 attgaaatat aatctttcta tgatttcccg ttcatcctta tttaactttg acattgcatt
       61 tcttagtgct tcaatcatca tttgtgtagc tacaactttt tcaacatcaa catttttatc
      121 ttctagatta tcttcaaaat tcccatcgtg atttagggac gaaaaaaata gcaagtggtt
      181 tttcttgtcc acctgctcta aatatttttc gtgttctctt tcttgccagt aaactttgta
      241 tatctgctca cttactttga ttttttgccc accgacataa aggtaatatt cttttgtcat
      301 ttatgtttcc tccattcttt ttttgtcttt atgttttcag acaaaaaaag gaggactcct
      361 gctcttgggc atggttagtc ctctagaatg aaagaaactc tttctaatag taattgtatt
      421 taatttttta actgagttat ctaacttgta aacagcgtaa accaaagaaa aaaggtaaat
      481 gtaatttaat tatatttatt tgcatatttc c
//
LOCUS       DARYSY010000180          473 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.183, whole genome shotgun sequence.
ACCESSION   DARYSY010000180 DARYSY010000000
VERSION     DARYSY010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.183"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>473
                     /locus_tag="TVR04_002046"
     CDS             <1..>473
                     /locus_tag="TVR04_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1270696.1"
                     /translation="GIPGPKGDRGETGPRGPQGIPGPKGEDGKPGEKGERGPAGPQGS
                     RGENGKDGAPGRDGQPGAKGEKGDPGKQGPKGDPGRDGKPGDKGERGPQGEKGLDGKP
                     GEKGPKGDTGKDGAPGRDGQPGPKGEKGDPGQQGIPGPKGDPGRDGKDGEKGERG"
BASE COUNT          153 a           94 c          167 g           59 t
ORIGIN      
        1 ggaattccag gacctaaagg ggaccgagga gagactggcc ctagaggacc tcaaggaatt
       61 ccagggccta agggtgaaga tggaaaaccg ggcgaaaaag gcgagcgggg ccctgctgga
      121 cctcaaggct ctagaggaga aaacggtaaa gacggggctc ctgggcgtga cggacaacca
      181 ggggctaaag gtgaaaaggg agatcctgga aaacaaggac ctaaagggga tcccggacgt
      241 gatggaaaac ctggtgacaa aggagaacga ggacctcaag gtgaaaaagg tctagacggt
      301 aagcctggtg aaaagggtcc taaaggcgat acaggaaaag atggtgctcc tggacgcgac
      361 ggacaacctg ggcctaaggg tgaaaaagga gaccctgggc aacaaggcat tcctggtccc
      421 aaaggtgacc ctggacgtga tggtaaagat ggagaaaaag gcgaacgtgg gga
//
LOCUS       DARYSY010000181          460 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.184, whole genome shotgun sequence.
ACCESSION   DARYSY010000181 DARYSY010000000
VERSION     DARYSY010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.184"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            90..>460
                     /locus_tag="TVR04_002047"
     rRNA            90..>460
                     /locus_tag="TVR04_002047"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          143 a           97 c          128 g           92 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag
//
LOCUS       DARYSY010000182          450 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.185, whole genome shotgun sequence.
ACCESSION   DARYSY010000182 DARYSY010000000
VERSION     DARYSY010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.185"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..>450)
                     /locus_tag="TVR04_002048"
     CDS             complement(<1..>450)
                     /locus_tag="TVR04_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEL1270697.1"
                     /translation="LVAFSQIDTLKYIPSLKIKNFIPSLILSVVIKLILIQKKKNAKK
                     FREGREYGSARWGNEKDIEPYIDKKFENNVLLTQTERLTMNNRPKNPKYARNKNVMVI
                     GGSGSGKTRFFVKPNLMQMHSSYVVTDPKGTLVLECGKMLERNGYEI"
BASE COUNT          120 a           83 c           58 g          189 t
ORIGIN      
        1 ttatctcata tccatttctt tccaacattt tcccacattc caagactaat gttccttttg
       61 gatcggttac tacatatgaa gagtgcattt gcatgagatt tggctttaca aaaaaccttg
      121 ttttaccact accagaacct ccaattacca ttacattttt atttctcgca tattttggat
      181 ttttaggtct attgttcatg gtaagtcttt cagtttgagt tagtagcaca ttgttttcaa
      241 acttcttgtc aatgtatggc tcaatgtctt tttcatttcc ccatcttgcc gatccatatt
      301 ctctgccctc tctaaacttt tttgcatttt tctttttctg tataaggatt aacttaataa
      361 ctactgatag aattagactg ggtataaagt tttttatttt taatgatgga atatatttta
      421 aagtatctat ttgactaaaa gctactagaa
//
LOCUS       DARYSY010000183          416 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.186, whole genome shotgun sequence.
ACCESSION   DARYSY010000183 DARYSY010000000
VERSION     DARYSY010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.186"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(138..>416)
                     /locus_tag="TVR04_002049"
     CDS             complement(138..>416)
                     /locus_tag="TVR04_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270698.1"
                     /translation="SVTIRDIFSPRSFTGVNKIVFTWKGYDLYLDSTNANRLSALGWG
                     SAIVSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRDVIHWVASQ"
BASE COUNT          165 a           83 c           48 g          120 t
ORIGIN      
        1 aaaaatgata ggtaaaacta tacccaatat gcagaaaaaa actttccaaa aaatagtatt
       61 atttttaaat aatttatcaa caaacaccaa taatatcaaa ttaattgcta aacacagtat
      121 ttttaaatat aatgctatca ttgtgaagcc acccaatgta tcacatctct tggaaaagtt
      181 cctacaaagg caacaattac tcctcttcct gcagcattag cataagatat tgatgcagac
      241 acaactccta aagcagctgc aagtacctta gatactatag ctgatcccca gcctagtgca
      301 gataacctat tcgcattggt actatctaaa taaagatcat agcctttcca agtaaaaaca
      361 attttattta ccccagtaaa tgatctagga ctaaatatat ctcttatagt aacaga
//
LOCUS       DARYSY010000184          407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.187, whole genome shotgun sequence.
ACCESSION   DARYSY010000184 DARYSY010000000
VERSION     DARYSY010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.187"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            205..>407
                     /locus_tag="TVR04_002050"
     CDS             205..>407
                     /locus_tag="TVR04_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1270699.1"
                     /translation="MKNYAIILAAGKGTRMNSGLPKVLHKVSGLSMLEHVLKSVSALA
                     PQKQLTVIGHQAEQVRAVLGDQSL"
BASE COUNT          138 a           85 c           91 g           93 t
ORIGIN      
        1 gctcagtaag caactaaaca aggacgtcaa gaaataggcg tttattgatc agctattgca
       61 gagctattta aaagcattta gagctttaag gtgggatact agaggattgg tatctcactt
      121 tttaggctga cttgtattaa taccaaaaag ccaaaaccag gcagataagc ataaggaatt
      181 agattaaaaa taaggaatca aaacatgaaa aactacgcca ttatcctagc agctggaaag
      241 ggaacccgta tgaattcagg gcttcccaag gtgctgcaca aggtatcagg cctaagcatg
      301 ctggagcatg tcctcaagag cgtctcagcc ctagctcctc aaaagcaact cacagtgatc
      361 ggtcatcagg cagagcaagt acgtgccgtc ctaggtgatc aatcact
//
LOCUS       DARYSY010000185          398 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.188, whole genome shotgun sequence.
ACCESSION   DARYSY010000185 DARYSY010000000
VERSION     DARYSY010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.188"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..330
                     /locus_tag="TVR04_002051"
     CDS             <1..330
                     /locus_tag="TVR04_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1270700.1"
                     /translation="EQGPRGENPTPTPTPDPMPDPAPKPMDPKPESKPEPKPTPQPET
                     KPQPKPAPQSEAEPQKPTKPSTITSQSSGKALPKTNDTGSLITVLGTGLLSLLGLGFL
                     TRRKRKQ"
BASE COUNT          148 a          119 c           56 g           75 t
ORIGIN      
        1 gaacaaggac ctcgtggaga aaatcctact cctaccccta ccccagatcc aatgcctgac
       61 cctgcaccta agccaatgga tcctaaacca gaatccaagc cagaacctaa acctacacct
      121 caaccagaga caaaacctca acctaaacct gcgcctcagt cagaagctga acctcaaaaa
      181 ccaactaagc catcaaccat tactagccaa tctagcggca aagcactacc aaaaacaaac
      241 gacacaggca gcttgataac agtattggga acaggcctac tctctcttct tggattgggc
      301 ttcctgacaa gacgcaaaag aaaacaataa ttaaaacact acccatagcc ttttaatcat
      361 tggctatcaa acaaatcaca aaaaagctta tcgtttta
//
LOCUS       DARYSY010000186          396 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.189, whole genome shotgun sequence.
ACCESSION   DARYSY010000186 DARYSY010000000
VERSION     DARYSY010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.189"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            94..261
                     /locus_tag="TVR04_002052"
     CDS             94..261
                     /locus_tag="TVR04_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1270701.1"
                     /translation="MENFVNLSEQELKEMTGGAVLETAAVIYVTKWVAGGAIALFGAG
                     AFVGYTEGKKK"
BASE COUNT          141 a           53 c           90 g          112 t
ORIGIN      
        1 ctccaagcat tataaatgcc atttttgaaa taggtaaaga atttggacat gcattagcaa
       61 aatggtttta acataataaa agggagaaaa agtatggaaa attttgtaaa tttatcagaa
      121 caagagttga aggaaatgac tggaggtgcg gtattggaga ctgctgcagt tatttatgtc
      181 acaaaatggg tagcgggtgg tgcgattgcc ctttttggag caggagcttt tgttggatac
      241 actgaaggga agaaaaaata atttctaagt acgaaacaat tgcaactatc gtgtttagag
      301 tctataaacg tactatattt caaaagttag gagcaaaatc taatgctcaa ataagaagag
      361 cttgggacaa gccaccccaa gctcttctta tttgag
//
LOCUS       DARYSY010000187          392 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.190, whole genome shotgun sequence.
ACCESSION   DARYSY010000187 DARYSY010000000
VERSION     DARYSY010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.190"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>392
                     /locus_tag="TVR04_002053"
     CDS             <1..>392
                     /locus_tag="TVR04_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270702.1"
                     /translation="RSKAQRATEIIQELIGQFSLATLLEILDLSRSTYYYQVKQLAQE
                     DKDMDLKELIQGIYDEHHGNYGYRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRK
                     RKYSSYKGEVGKKADNLIKRQFEGSKPY"
BASE COUNT          131 a           76 c           78 g          107 t
ORIGIN      
        1 acgaagcaaa gctcaaagag caacagaaat catccaagaa ttaatcggtc aattttctct
       61 agcaactttg cttgaaatcc ttgatttatc gcggtcaacc tattattatc aagtcaagca
      121 actagctcaa gaagataagg acatggactt aaaggagctc attcaaggca tctatgatga
      181 acatcatggc aattatggct atcgtcgcat tcatctggaa ctaagaaatc gtggttttat
      241 cgtcaatcac aaaaaagtac aacgtttgat gactgtcatg ggcttaaaag ctcgtatccg
      301 tcgtaagcgc aagtattctt cttacaaagg tgaggttggc aaaaaggctg ataatctgat
      361 taaacgtcag tttgaaggtt ctaagcccta cg
//
LOCUS       DARYSY010000188          340 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.191, whole genome shotgun sequence.
ACCESSION   DARYSY010000188 DARYSY010000000
VERSION     DARYSY010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.191"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            8..79
                     /locus_tag="TVR04_002054"
     tRNA            8..79
                     /locus_tag="TVR04_002054"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40..42,aa:Gly,seq:gcc)
     gene            88..172
                     /locus_tag="TVR04_002055"
     tRNA            88..172
                     /locus_tag="TVR04_002055"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:122..124,aa:Leu,seq:taa)
     gene            187..260
                     /locus_tag="TVR04_002056"
     tRNA            187..260
                     /locus_tag="TVR04_002056"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:221..223,aa:Arg,seq:acg)
     gene            267..340
                     /locus_tag="TVR04_002057"
     tRNA            267..340
                     /locus_tag="TVR04_002057"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:301..303,aa:Pro,seq:tgg)
BASE COUNT           75 a           78 c          106 g           81 t
ORIGIN      
        1 tagagttgcg aacgtagttc agtggtagaa caccaccttg ccaaggtggg ggtcgcgggt
       61 tcgaatcccg tcgttcgctt ttggggagcc ggggtggcgg aactggcaga cgcacaggac
      121 ttaaaatcct gcgatggtta gcatcgtacc ggttcgattc cggtcctcgg catagcataa
      181 ggaaaagcac ccttagctca actggataga gtacctgact acgaatcagg cggttagagg
      241 ttcgactcct ctagggtgca tagttacggg aagtagctca gcttggtaga gtacttggtt
      301 tgggaccaag gtgtcgcagg ttcgaatcct gtcttcccga
//
LOCUS       DARYSY010000189          339 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.192, whole genome shotgun sequence.
ACCESSION   DARYSY010000189 DARYSY010000000
VERSION     DARYSY010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.192"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..>339
                     /locus_tag="TVR04_002058"
     CDS             <1..>339
                     /locus_tag="TVR04_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009537685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1270703.1"
                     /translation="PIDLLFQLSIPAVIGMIVIGLYPLMDGIFAGNIIGQTAMTACGV
                     AMPLTFFNSGVSTLIGVGSASVLSRAIGKGDKKTVDKIMGNLIFWVILFSSIITIGGI
                     ILAPHFLDMVG"
BASE COUNT          105 a           48 c           66 g          120 t
ORIGIN      
        1 acccatagat ttactttttc aattatctat ccctgctgta ataggaatga tagtaatagg
       61 tctttatcca ctaatggatg gaatttttgc gggaaatatt ataggacaaa cagcaatgac
      121 agcttgtggt gtagctatgc cacttacatt tttcaatagt ggtgtatcta cacttattgg
      181 cgtaggttca gcatcagttt tatcaagagc tataggaaag ggcgacaaaa aaacagttga
      241 taaaattatg gggaatttaa tcttttgggt tattttattc tcatcaatta ttacaatagg
      301 tggaattata cttgcaccac attttttaga tatggttgg
//
LOCUS       DARYSY010000190          332 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.193, whole genome shotgun sequence.
ACCESSION   DARYSY010000190 DARYSY010000000
VERSION     DARYSY010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.193"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(197..284)
                     /locus_tag="TVR04_002059"
     tRNA            complement(197..284)
                     /locus_tag="TVR04_002059"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(248..250),aa:Ser,seq:gct)
BASE COUNT          125 a           67 c           58 g           82 t
ORIGIN      
        1 aatttttgta acgggatttc ggataatcat tgataaatat ggagaaatag ctactctaaa
       61 aagaagaacc aaggtcaaag ccagtaaagc taatgatgtt aaccaaaaaa agagacgaga
      121 taggttaagc tttttcaata aaatcacctc taaaaataaa aaaacgatta tcagtatgat
      181 aatcaccttt acaatacgga gaataaggga ttcgaaccct tgcgccagtt acccgaccta
      241 acgatttagc aaaccgtcct cttcagcctc ttgagtaatt ctccaaataa tgatgggcac
      301 gagtggactc gaaccaccga cctcacgctt at
//
LOCUS       DARYSY010000191          329 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.194, whole genome shotgun sequence.
ACCESSION   DARYSY010000191 DARYSY010000000
VERSION     DARYSY010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.194"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            140..>329
                     /locus_tag="TVR04_002060"
     CDS             140..>329
                     /locus_tag="TVR04_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270704.1"
                     /translation="MIRLIDRYGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTS
                     LDYALPNSSMLSRWIAQYK"
BASE COUNT          116 a           52 c           66 g           95 t
ORIGIN      
        1 aaaatctaac aattgggggg ctatttttat gacattgagt tatgaagaca aggttcaaat
       61 ctatgagcta cggcacattg gaaagtccat taaatgctta tcagaaaagt ttagtattgc
      121 agaatctgac ctcaaataca tgattcgcct gattgacagg tatgggttag ccattgtcca
      181 aaaaggtaag aatagttatt attctccaga actgaagcaa gagataatag ataaagttct
      241 gattgatggt caatctcaaa aacagacgtc cttagactat gctttaccaa attctagtat
      301 gctttcaagg tggatagcgc aatacaaga
//
LOCUS       DARYSY010000192          329 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.195, whole genome shotgun sequence.
ACCESSION   DARYSY010000192 DARYSY010000000
VERSION     DARYSY010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.195"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..>329)
                     /locus_tag="TVR04_002061"
     CDS             complement(<1..>329)
                     /locus_tag="TVR04_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1270705.1"
                     /translation="AQIVLDRFHIVQHLGRAMNRIRTQIMNSFDRKSHEYKALKRYWK
                     LIQQDSSKLSDKRFYRPTFRMHLTNKEVVERLLSYSDELRKHYDLYQLLLFHFQEKQA
                     DHFFGLI"
BASE COUNT           95 a           66 c           79 g           89 t
ORIGIN      
        1 aatcaggccg aaaaagtggt cagcttgctt ttcctggaag tgaaaaagca gaagctgata
       61 aaggtcataa tgctttctaa gctcgtcaga gtagctcaaa agacgctcga ccacctcctt
      121 gtttgtcaaa tgcatgcgaa aagtcgggcg gtaaaaacgc ttgtcactga gtttgctgct
      181 atcttgttga atcagcttcc agtaacgttt caaagccttg tattcgtggg attttcgatc
      241 aaaagagttc atgatttgag tacggatacg gttcatggca cgtcccaaat gttgcacaat
      301 gtggaaacga tcaaggacaa tctgagcgt
//
LOCUS       DARYSY010000193          328 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.denovo.196, whole genome shotgun sequence.
ACCESSION   DARYSY010000193 DARYSY010000000
VERSION     DARYSY010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.denovo.196"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            complement(<1..271)
                     /locus_tag="TVR04_002062"
     CDS             complement(<1..271)
                     /locus_tag="TVR04_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1270706.1"
                     /translation="MTYLPIGSIVQLENGTAKLMITTRFALYNDNGNIGYFDYAGCLY
                     PSGLTDNQGFFFNHENIKKVWFEGYIDDSEREAQDFFKKEAGHIKY"
BASE COUNT           99 a           66 c           47 g          116 t
ORIGIN      
        1 gatatttaat atggcctgcc tcctttttaa aaaagtcttg agcttctctt tcactatcat
       61 caatatagcc ttcaaaccag acttttttaa tgttttcgtg gttgaaaaag aagccctgat
      121 tgtcagtcag tccactagga tacaagcacc cagcatagtc aaaataaccg atattgccat
      181 tgtcattata tagggcaaat ctggttgtaa tcattaattt tgcagtacca ttttctaatt
      241 gaacaatact gccgataggt aaataagtca tgtcattctc cctaatgttc tctattaaac
      301 agtttctttg aagtttttct cccataaa
//
LOCUS       DARYSY010000194        27494 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.guided.026, whole genome shotgun sequence.
ACCESSION   DARYSY010000194 DARYSY010000000
VERSION     DARYSY010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27494
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.guided.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            56..1405
                     /gene="gdhA"
                     /locus_tag="TVR04_002063"
     CDS             56..1405
                     /gene="gdhA"
                     /locus_tag="TVR04_002063"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1270707.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGKVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDTDVPAGDIGVGSREIGYLFGQYKRLNAFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     GLIEHGVTAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            1537..1947
                     /locus_tag="TVR04_002064"
     CDS             1537..1947
                     /locus_tag="TVR04_002064"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1270708.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIVSMGFVDLVMFNPVLTAKREAFEAEESCLSLTGQRRTTRYQEIKV
                     DYLDTHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(2139..4145)
                     /locus_tag="TVR04_002065"
     CDS             complement(2139..4145)
                     /locus_tag="TVR04_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1270709.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTATQLAAYLDDAEADFKQTSPDGTSIRVQAGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTTNEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANATLPATGTSQHSAAAMTILGLLTLTGASLFKKKEGQ"
     gene            4593..6314
                     /locus_tag="TVR04_002066"
     CDS             4593..6314
                     /locus_tag="TVR04_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270710.1"
                     /translation="MLTLIVQHIRQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSAALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVKEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQHELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            6316..8067
                     /locus_tag="TVR04_002067"
     CDS             6316..8067
                     /locus_tag="TVR04_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1270711.1"
                     /translation="MTLFIKLIKEIKAVTLAFSLAIGFLLVATAGGQMAPLLLQQTID
                     HYLTPIARGKEVPIEGFQRLLLLYLLLIVITAVLRYISYRMLVYSSNRIVANLRNRAF
                     NVMQRLPIAYFDHQPAGKIATRIVNDTETLKNQFYDNLLSQIIVSASQIVFIYVVMIY
                     LDVKSGLLLLLIMPLFYGMQWLYKSLTDQPMKDFYQARSAVNTQVNETMNGVSIIQLY
                     HQEDTILEEFEEQIHQMKTADDRIIFAESVASWTLTELVKYGMIAAILAVIGYQFLQG
                     RSGITVGKLFIYVNYLMRLFDLLSMLVRQLPNIQRSTATGTRLMKLLEAQTEPDKARA
                     IELTDGTVDFTKVYFAYENGKTVLSDITIHADKGETVALVGHTGSGKSSIMNLLYRFY
                     DVQSGLITVDGQNIQEYSRESLRSQMGIVLQDPYLFTGTIASNITMGNPAYSDQDILD
                     ALEKVGVSSMIARLEKGIHEPVYEKGSSYSSGERQLIAFARTLIADPKILILDEATSH
                     IDTETEDIIQQAMEVLKKGRTTFIIAHRLSTIQSANQILVLDKGRIVERGTHQELLDQ
                     QGIYAEMSKLQEEVAVQ"
     gene            8603..9481
                     /gene="mvk"
                     /locus_tag="TVR04_002068"
     CDS             8603..9481
                     /gene="mvk"
                     /locus_tag="TVR04_002068"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1270712.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIISQVPQKRGMGSSAAVSIAAVRA
                     VFSYFQQPLSGELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCLTEAVEQAIKTKDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVEAALEAGALGAKMTGGGLGGCMIALAERVTDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            9463..10407
                     /gene="mvaD"
                     /locus_tag="TVR04_002069"
     CDS             9463..10407
                     /gene="mvaD"
                     /locus_tag="TVR04_002069"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1270713.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEVKMIPSTSSISLTLEGMYT
                     TTSLSFLLPSAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQAFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGRLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQKGYPCYFTMD
                     AGPNVKVLCLEEDLERLSRLFEREYRIIASKTKELPDV"
     gene            10400..11398
                     /locus_tag="TVR04_002070"
     CDS             10400..11398
                     /locus_tag="TVR04_002070"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1270714.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYVDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVLLTLRALAAYYQVHLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRCKVSQWLTEMTLKELMAAHWGYTIETIEPALPCWFLVGWTKVPSISREM
                     IQLVNKNISYPFLEQSQKVTQEVMTALQLGQSERLKAGIEKASQLLQGLASVIYHPKL
                     MQLVQACQGLDAAAKSSGSGGGDCGIALVFDTKDIEPILARWQQAGIVLLYQEEWG"
     gene            11401..12393
                     /locus_tag="TVR04_002071"
     CDS             11401..12393
                     /locus_tag="TVR04_002071"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1270715.1"
                     /translation="MTNRKDDHITYALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVA
                     LELVETYPVEQVIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(12668..13951)
                     /locus_tag="TVR04_002072"
     CDS             complement(12668..13951)
                     /locus_tag="TVR04_002072"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1270716.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDIANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSARCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARNGAYRGLSSWHVDTSKNSLCGELTLPMPIASKGGSIGLNPT
                     VNVARSLLEQPNAKVLAQIITAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAKQLLIAIRLNQS"
     gene            complement(13938..15116)
                     /locus_tag="TVR04_002073"
     CDS             complement(13938..15116)
                     /locus_tag="TVR04_002073"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1270717.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAICFHIPFPKLALKGLHKIMTKSLLADNHKEKLYENFQASIAYSKQIG
                     NIYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQ
                     ALLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN
                     "
     gene            15301..16140
                     /locus_tag="TVR04_002074"
     CDS             15301..16140
                     /locus_tag="TVR04_002074"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1270718.1"
                     /translation="MTKADQIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWRAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACHPKLLLHVPDGTDFFDIRPEDFELQDYHPVKPQLTFD
                     LAI"
     gene            16221..16718
                     /locus_tag="TVR04_002075"
     CDS             16221..16718
                     /locus_tag="TVR04_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1270719.1"
                     /translation="MTKKIIAIWAEDEAGLIGTCGKLPWYLPKELQHFKETTLHQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTKNSHYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGHFDAIIKTVVHHRFEGDTYSPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            16738..16908
                     /locus_tag="TVR04_002076"
     CDS             16738..16908
                     /locus_tag="TVR04_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1270720.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            16944..18173
                     /gene="clpX"
                     /locus_tag="TVR04_002077"
     CDS             16944..18173
                     /gene="clpX"
                     /locus_tag="TVR04_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1270721.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVR
                     ITKEAVEGQSKPVLEIA"
     gene            18183..18782
                     /locus_tag="TVR04_002078"
     CDS             18183..18782
                     /locus_tag="TVR04_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1270722.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHEPSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            19146..22157
                     /locus_tag="TVR04_002079"
     CDS             19146..22157
                     /locus_tag="TVR04_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1270723.1"
                     /translation="MTIKKCPQILALSLALAALASQAQAVHALEQQEISVKQAQESSD
                     WFNEDEDFRAVKSNTSTEIDSTVTDLFGDAESKTKAGKEELKAPSSKQEALPAEPQKE
                     KETSAKPTDHATAQVEEAQPEQDSDNPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLT
                     LPRIGADKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRNILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLADSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERAFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHVVLRTKSGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNKWLAEDFTYTGQMITGFSASGLRKVKRNKHLVLPKDYQGQPLTAIADNA
                     FRNVDFHDKALRKYDLERVTLPSTIQKIGAFAFQSNNLESFEASEDLVDIGQGAFMNN
                     RIEILTLNDKLRVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVVFMGDKLTS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDNLIRIQAEAFKANRLQ
                     GVTVPDTVISISFNAFDNNSDDKVILRTINHNKNLLADGDGFIVDPDLLSADQSSVQA
                     VLEDLQRLDLASLRADTAAHFTTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKSADIALSNHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKISRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKKLLPKTGA
                     FKEAWVTMIGMLVLLAAALLKGDSRYKKRSK"
     gene            complement(22341..24434)
                     /locus_tag="TVR04_002080"
     CDS             complement(22341..24434)
                     /locus_tag="TVR04_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1270724.1"
                     /translation="MATYYGKDPFGNMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAVAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEIAK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGANDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDSADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLAEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            24805..25224
                     /gene="ndk"
                     /locus_tag="TVR04_002081"
     CDS             24805..25224
                     /gene="ndk"
                     /locus_tag="TVR04_002081"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1270725.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDALINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            25725..26531
                     /locus_tag="TVR04_002082"
     CDS             25725..26531
                     /locus_tag="TVR04_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1270726.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVADTPVLNRSEKAVY
                     ANDFGSGNRASDYVPAAKAWSFEAYPDYYRVLGASHLNPAIFPEAGNMSYSPLDELGR
                     TQVARGTINYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     MPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTINYATGAFQSN"
     gene            complement(26828..>27494)
                     /locus_tag="TVR04_002083"
     CDS             complement(26828..>27494)
                     /locus_tag="TVR04_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1270727.1"
                     /translation="PILMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLS
                     PEEAYRVLSANELPAEKVVWLTFDDSMVDFYNVAFPILKKHGIKATNNVITGFTEAGN
                     AANLTLDQMKEMKQAGMSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIA
                     IAYPAGRYTDTTLKIAEDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNT
                     ISQ"
BASE COUNT         7690 a         5343 c         6429 g         8032 t
ORIGIN      
        1 aaatttataa tattgactat acttaaaata gaatgaagaa atgagaggat atataatggt
       61 atcagcaaaa gactatgtag ctagtgtttt tgataaggtc aaaagggata atccgcatga
      121 gactgaattt cttcaggcgg tcaaggaggt atttgattcc ttgattcctg tttttgaaaa
      181 ataccctaat tatattgagg aaaatctatt agagcgcttg gttgagcctg agcgtgtgat
      241 ttcttttagg gttccttggg ttgatgatca gggcaaggtt caagttaatc gtggctaccg
      301 cgtgcaattt tcatcagcta ttggcccata taagggaggg cttcgctttc acccttctgt
      361 caaccagtct atagttaaat ttcttggctt tgagcagatt ttcaaaaatg ctctgactgg
      421 tcagcctatt ggaggaggaa aaggaggatc aaattttgat cctaaaggca aatcagacct
      481 agaaatcatg cgcttcacac aaagctttat gacagagcta caaaggcata tcggccctga
      541 tactgatgtc cctgccggtg atattggtgt gggaagtcgt gaaattggtt atttgtttgg
      601 gcaatataag cgccttaatg cctttaagaa tggtgtgttg acaggaaaag gtctagccta
      661 cggtggctcc ctagctcgca cagaggccac aggctatggc gtggtttatt ttgctcagca
      721 aatgctggcg gctaaggggc aggacttggc tggtaaaaca gctattgtat ctggatcagg
      781 aaatgttgcc atttacgcaa cggaaaaatt gcaggcctta ggtgttaagg tattagcagt
      841 gtcggattcc tctggttacg tttatgatga taagggcatt gatcttgaga ccctaaagca
      901 aatcaaggaa gtgaagcgtg agcgtatcaa gacctatcta gagagtcacc cggctgctgt
      961 gtttacaccg gctggtgagg gatccatctg gactattaag gcagaccttg cctttccatg
     1021 tgcgactcaa aatgagctac aagaggcaga tgctaaaggc ttgattgagc atggggttac
     1081 agctgttgtc gaaggggcta acatgccctc aaccttagag gctattgagc aatttcagca
     1141 ggctggggtt ctttttggcc ctgctaaagc agcaaatgct ggcggtgtag cagtttctgc
     1201 gctggaaatg gcacaaaata gcggacgtac cgcatggacc tttgaagagg tggatcatcg
     1261 attgtatgac atcatgaagg ctatttatca aaaagcagcc gcagccgcca aggaatgtgg
     1321 tcaagaaggc aacctagtgg tgggagctaa tattgcaggc tttctcaaag ttgctcaggc
     1381 catgtcagca cagggaatcg tttaagagct gtggctggta tatgctgcat atatcagtag
     1441 ggttagcaca ttagtcttag cttaatgacg ttaggataca cgatcggtca tctagacaat
     1501 gcatgccgat tagagcaata aatcaaggag aagatgatga tcaaaaaaat cgtgaaggac
     1561 acctttttct tgcagcaaaa ggcacagcca gcaacgaaaa aggacctttg gattggtcaa
     1621 gacctgcagg ataccttagc ttattatcgt gatagctgcc tggggctggc tgctaatatg
     1681 ataggggaaa acaagagggt tattattgtt agcatgggct ttgtggattt ggtgatgttt
     1741 aatcccgtat taactgctaa gcgtgaagcc tttgaagcag aggaatcctg cctatcacta
     1801 acaggccaac gtaggacaac gcgttatcag gagatcaagg ttgattatct tgatacacat
     1861 tggcacaaga aatccctacg attgacaggc ttaccggcac agatctgcca gcatgagctg
     1921 gatcatctgg agggcatatt aatttaaatc atgaccaccc gttactgaag tgcccccatt
     1981 cgttagagtt tctatctaac ttttggaagg gcagtctata gatgggtggt ttatttgtct
     2041 cgctccacag gtgcgaggcg aactaaaagt cgtataatca aaaaaccggc tgtatgctta
     2101 agatacagtc ggttattgct gttatagcta agccggtttt attggccttc ctttttcttg
     2161 aaaaggctag caccagttaa ggttagtagt cctaggattg tcatggcagc agcagaatgc
     2221 tggcttgttc ctgttgctgg taaggtagca ttagcttgct ttttagctgc tagaggcttg
     2281 atgcttgtgg caggattagc attttgagca ggcgtaaata gatcagagac gagctcagta
     2341 gcaagcacct tgccctcacg attcttaaag acgcggttga tgatctcgtg cttgccggta
     2401 tggtcacttt gagtagagcc ttcaagactg gcagtgacat aggttttcac accgttaata
     2461 ccagcactta cagtctttcc agctgcttca aggtccttga tgtattcgat aaagacctca
     2521 gtatcaggat taatggctcc tagtagctta gcgtccttaa agacggagaa gccatcacca
     2581 ccgccatata ggaagtcgtt gatgattagg gtgtattgag ctgctggatc aatttcttca
     2641 ccattatctt tataagcctt tactacctta aacggtgttg aaggatcgtt agcctcatta
     2701 gttgtataag tgtatttgag tccagacatt tgaaggaagt atttttggtc ttcatcgtat
     2761 tgttggttca agacatcata aatttgttgg ccagtcattt gaacgacctg aagaatattg
     2821 ccaaaaggtt gaacagcctg tgcagctccc caggtaatgg tttgatcctc tttgaccacc
     2881 aagtcagcgc gaataccgcc attatttgtc atggcaaaat caacatgagg gaaggttttt
     2941 ctaccaatgg ttaattgggc agttgttatc aaattgccaa caggagattc cttgtcttcg
     3001 ttttctgttt tagaaatcgt tgaagaggta gctgctgtac cgatctttag ctcggtaacg
     3061 gttttgacaa tgtcattggc ttgatcaaca atggcttgaa tgtcggcatt gcctgttttt
     3121 atgccaggag caacggcaat gacctttgct tcaggagtgg ctacaaaatc attgaggtca
     3181 gtgtctagtg ttccacgaac atctgcatag gctttcccct gtgaaacagc ctgaacgaca
     3241 cgtgttgtgc caatggtacc gttggtgtat tggtggttgt gaccagcaaa gacaatatcc
     3301 acactatgct caggataaag ctggttaacc ttttccataa ctgctgccat ctcatcatga
     3361 actaccccgt tatcacttgt tgctgggata tgagctagga caacaatcgc attgacctgc
     3421 tgctcttgga gctctttagc atatttaacg atggtttctg cagagtctag gtaatcatat
     3481 tgttcataat tttgttttag gacaaggttt ggaatttctg ttgttacaac accgataaag
     3541 cccaccttga ctgacttatc attaactggg acttctttga cagcataagg cttccagcca
     3601 aaaggaatcg tgttggtctc cttgtcaacg acatttgcaa tgacaagggt ttgatttgaa
     3661 gcttcatgct cgtattgctt agtaatgtcg ttgatagctg agtcttcagc aggtgcagtg
     3721 cctgtcatga tacggttgaa ttcagctaag ccctcatcga attcgtgatt cccaagggtt
     3781 ccgtattcaa agcccatctg gttgaatacc ttaaccgttg gctcgtcctg taatagtcca
     3841 gaattagcag gactagctcc gaccatatct cctgcttgaa cacgaatgct tgtcccatct
     3901 gggcttgttt gcttaaagtc agcctctgca tcgtccagat aggcagctaa ttgtgtggca
     3961 gtacctgcgt tagatacctt tccttctggc atgtaggcag agccggttgt gtctaaggca
     4021 ccatgaaagt cattgactcc aagaaattgc acgtctacct gatcggcctg cacgccggtt
     4081 actagcatag aaactccggc aaagacacca agaacactac tttttaaaac aaaatgcttt
     4141 ttcataaacg ctcctaaaag tttaaagtat tgtcacaagt taagtgtact attatttaaa
     4201 tgagaattca acaaaaatta ataaaaaagc taacaaaaat tcaacgatag cgtttgctaa
     4261 tcactgaaaa cgtttaaaat gcaaacattg gaagcgtttt ttgcaaaaaa tagaagaact
     4321 atccaaaaaa ggctttacaa gcccagtatt ctatgataag atgttaggca gattaaaaga
     4381 aaggagaaat taataatgaa ccgtttcatt caactattta accattatta cgatagtctc
     4441 ctttctaacc aaaacagtta gtttctttta gtttcactaa atagaaataa taaagcccgc
     4501 ggtaggaagg atatcttatt gcgggctttt tgtgtgcaaa aatcctattt taagacagct
     4561 tgaaataggt tagttcagaa atggaggata tgatgctgac cttaattgtt caacatatta
     4621 ggcaaaagaa atggatttat atccttattg caatgacttt agtgatatat gatgcctcac
     4681 ttgtgatacc aacaagggtt attcaagact tggttgattt gatgtcaagg catcagctaa
     4741 gctcagcggc attggtgagg catgttatca ttcttttggc tacggcagtg gtgtcttatg
     4801 gagttgctta tttgtggcat cttcatttgt ttcaggaggc agttcatttt aagtttgata
     4861 ttcagcagcg tgcctttcga aagcttgttt ttatgagaac gcctttttat gagaaatttc
     4921 gctcaggtga catgatcacg cgtttttcaa cagatgtcga agcacttatg gaccttatcg
     4981 gctatggctt gatgattatc ctatatgctg gtggtatgat tgcttttatt attccgacca
     5041 tgtttttgat ttcttggaaa atgaccttga taggaatagt accgattttg cttatgatgg
     5101 tgatgatcta tggtgttacg aaaaagcaag agcatttggt taaagaggcg cgtgaggcga
     5161 tttcaagcct tagtgatgag gtactagaaa ccgttgaggg cattagagtg atgcgtgctt
     5221 acagtaaaaa agattatttg gcacttcatt ttgctcaaaa gactcagaat ttggcagata
     5281 aatggaatca ggtggccaag tatcgtgcct tgtactttcc tctttacagc gtcatgattg
     5341 ccattagtac agtaatcatt ttaatggtag gcctacagct catagcaagc tcagaggtaa
     5401 cacttggtca agtcattgcg ctgcagcttt atctggtgtc tttggtggag ccctttggca
     5461 tgctgtcaga ctttattttg gtttatcaga caggaaaaac ctcttttggt aagattaatg
     5521 agctcattga aacaagtgat gatatggagc ctgatggcca gcatgagtta gagagctttg
     5581 atcagattgc ttttatagac tatagcttta cctatgccaa tagttctagg cctagcttag
     5641 aaaagatcaa tttaaccctg aaaaagggac aaaccttagg gattgttggt aaaacaggct
     5701 ctggtaaaac aacccttgtc aggcagtttt tgagacaata ccctcttggg caggggcagc
     5761 tgatgattaa tcatcgtagt gtcttggatt ataagcgtca atcacttgag cgtcagattg
     5821 gctatgtgcc acaggagcat atcctgtttt caaaaacggt tgctcaaaac attgcgatgg
     5881 ggaaaaaggc agctacaact gaggaaatct tggaggcgat tgaaactgcg gcctttacgc
     5941 gtgatgttca aggaatggca aagggcttgg atactgagat tggagagcgt ggtctgtcta
     6001 tttcaggagg tcaaaagcag cgtatttcga ttgccagagc ctttttgtcc cagccagatt
     6061 tgctgatttt agatgattcc ctgtcggcag ttgatgctag aacagagact gatattattc
     6121 gacacattca agacgaaaga aagggaaaga caacacttat tgttagccat cgcttgtctg
     6181 cgattcagca tgccgattgg gttattgttc tggatcaggg gcagatagta gaggaaggtc
     6241 agccccaaca acttttagct cagaagggct ggtattatga acagtaccag cgtcagcagg
     6301 ctcaggaggt ttaagatgac cctatttata aaattaataa aagaaattaa agctgtgacc
     6361 ttggcttttt ccctggcaat aggctttttg ctagtggcaa cagctggagg tcagatggct
     6421 cccttattgt tgcaacaaac gattgatcat tacttgactc cgatagctag aggaaaagag
     6481 gtaccgattg aaggctttca gcgcttgctc ctgctgtatt tgctgttaat tgtgataaca
     6541 gcagttttgc gttatatctc ttatcgaatg ctggtttatt cctctaatag gattgttgct
     6601 aatcttcgta atcgagcctt taatgtgatg cagagactgc cgatagctta ttttgatcat
     6661 cagcctgcag gaaagattgc aactaggatt gttaatgata ctgagaccct gaagaatcaa
     6721 ttttatgata accttttgtc tcaaattatt gttagtgctt cacagattgt gtttatttat
     6781 gtggtgatga tttaccttga tgtgaaatca ggcttgctct tgctgcttat tatgcccttg
     6841 ttttatggca tgcaatggct gtataaaagc ttgactgacc agccaatgaa ggatttttat
     6901 caggccagga gtgctgtcaa tacgcaagtc aatgaaacca tgaatggtgt ttctattatt
     6961 cagctttatc atcaagagga tacgatctta gaggaatttg aagagcagat ccaccagatg
     7021 aaaacagctg atgataggat tatttttgca gagtcagttg cttcatggac gctgacggaa
     7081 ttggtaaagt atggcatgat tgccgctatt ttggctgtta ttggttacca gttcttgcag
     7141 gggagatcag gcatcacagt tggtaagctc tttatttacg ttaattattt gatgcgcttg
     7201 tttgatttat taagtatgct ggttaggcag ctgcctaata ttcagcgctc aacagcgaca
     7261 ggaacgcgcc tgatgaagct gcttgaggcg cagacagagc cggataaagc acgagcaatt
     7321 gagctaacag atggcactgt ggattttacc aaggtatatt ttgcttatga aaatggcaag
     7381 acagttttat ctgatattac cattcatgct gataaggggg agacggttgc cctagtaggg
     7441 catactgggt ctggtaagtc atctatcatg aatttgctgt atcgctttta tgatgtacaa
     7501 tcaggcctca ttacagttga tgggcaaaat attcaggagt attctagaga aagtctgcgc
     7561 tcacagatgg gtatcgtctt acaggatcct tatttgttta caggaacgat tgcttctaat
     7621 atcacgatgg gaaatccagc ctattcggat caggatattt tagatgcttt ggaaaaggtc
     7681 ggagtctctt cgatgattgc tcgtctggaa aagggcattc atgagcccgt ctatgaaaaa
     7741 ggctcctctt attcgagtgg cgagagacag ctaattgctt ttgctaggac attgattgcc
     7801 gaccctaaaa ttttgatctt agatgaagcg acctcgcaca ttgatactga gacagaggac
     7861 atcattcaac aggctatgga ggtcttaaag aaaggccgaa caacctttat cattgcccat
     7921 cgcttgtcta ccattcaatc tgctaatcaa attttagtat tggataaggg gaggatcgtc
     7981 gaaagaggaa cacatcagga attgctagat cagcaaggca tttatgctga aatgtccaag
     8041 ctacaagaag aggtggctgt acagtaatgc tttttagtga tagttatcta aacagctcct
     8101 tttccagatt atgttaagag tggtagtctg tgaagtagga acaacgttta ggctttgtgt
     8161 ctaagcctct aaggctttta agaggctgga tcagggctca gcgtcaacaa aatcacatgt
     8221 cactttatca cagcatgctg tgatgaagtg ttttttgtgt cgtcctgctg aggagaaggc
     8281 tctcacagtc agcacttgtc tgactccttc atcgaagtta ggtgattgat acgatatctg
     8341 aggtacagca cttgctcctt gttagcctaa gcttgttttg agatcagcct gtcagcaatc
     8401 tatgctttgt gtctgacctt tagcagcttg tagatgaagt agggctaaag gacactttaa
     8461 ttgatgagga attaccttaa aaatccattt cccagatgag ataagaacgg tctaaaaggg
     8521 gatagataat cgcaattttt aacaatttag tgtaaaatag taaggtgaat gttttgatga
     8581 agtagacgaa aagatttagg atatgaataa gacaattgga tatggcaagg cacacagcaa
     8641 aatcatttta atgggggagc attctgtggt ttatggttac cctgcgctgg ccttgccctt
     8701 aaaagacatt gaagtgacct gccggatttt ccctgcagca aaacctttag cctttgattt
     8761 ttatgatccc ttatcaacgg cagtttatgc agccttggag catttggggt gcttggcaga
     8821 gcccattcat tatgatatta tttctcaggt accacaaaag cggggcatgg gttcctcagc
     8881 agctgtttcg attgcagctg ttcgagctgt tttttcttat tttcagcagc ccttgtcagg
     8941 tgagctcttg gaaatcctgg tgaataaggc ggaaatcatt gcccatacca atcccagtgg
     9001 cctagatgct aagacctgcc ttagtgataa ggccatcaaa tttattagaa atgttggctt
     9061 tgataccatt gatattcagt taaatgctta tttggtcatt gctgatacag ggattcaggg
     9121 gcatacgcgt gaggctgtca ataaggtggc tcaatttgag gaggaaaatc ttcctcattt
     9181 agccaagctt ggctgcttaa cagaggctgt tgagcaagcg attaagacaa aggattgcct
     9241 agctattgga cgattcatga cacaggcaca tgaatcacta aaggctattg gtgtcagtgt
     9301 ggcaaaggcc gatcagctgg tagaagcagc tcttgaggct ggcgctttag gcgctaaaat
     9361 gactggtggc ggcttaggag ggtgtatgat cgcattagct gaaagggtaa cagacgctca
     9421 gcaaatcagt aagaaactaa aagaagaggg agctgtaaat acgtggattc aaatactgta
     9481 acggtaactt cctacgctaa tattgctatt gtcaaatact gggggaaaaa agatgaggtt
     9541 aagatgatcc catcaacctc tagtatttct ttgaccttgg aaggcatgta cacaacaaca
     9601 agtctttctt ttttacttcc ctcagcaaag ggagatcagt tctatatcaa tggtgtcttg
     9661 caggacgcca aggagcatgc taagattact gcgattttgg atcagttccg tcagaaggac
     9721 caggcttttg tcaaggttga ggcaagcaac agcatgccaa ctgcggcagg tttatcctca
     9781 agctctagtg gcttatctgc tctggtaaag gcctgtaatc agctttttca agctaagcta
     9841 agtcaagaag agcttgccca aaaggctaag tttgcctctg gctctgcgtc gcgttctttt
     9901 tttggccctg ttgctgcctg ggataaggat acaggctcta tttataaggt caaaacagat
     9961 ttaaagctgg ccatgattat gctggtcttg aacgatgcta gaaagcccat ttcgagtcga
    10021 gaggggatga agcgctgcag tacaacctca acaagctttg accagtggct ggcccagtca
    10081 gaaagtgatt atcaggccat gctgcgtgcc cttagtgaca atgattttga aacggttggt
    10141 cggctgacag aagcaaatgc tctagccatg cacgcaacga ccaaaacagc cagtccttcc
    10201 ttctcttacc taacagaggc ctcctatcag gccatgctaa gggttaaaga gcttcgccaa
    10261 aagggctatc cttgctattt tacaatggac gctggcccaa atgtcaaggt gctttgttta
    10321 gaagaggact tagagcggct gtcgcgcctt tttgaaaggg agtatcgtat cattgcctca
    10381 aaaacaaagg aattaccaga tgtctaaata ccatgttcaa gcaggaggaa agctgtatct
    10441 gacaggcgaa tatgcgattc taaggccggg gcaaacggcg ttaatttgct atattcccat
    10501 aatgctgaca gctgtcattg aagcagcaga ggctgttagt atcagctcag atatgtttga
    10561 ccatgctgct gatttgtcac cggataagga ttataggctg attcaagcct ctattgaagc
    10621 ctttagttta tatgtagata aggatattaa ggagctgcca gccttttctt tgtctattac
    10681 tggtaagctt gagcgtgacg gtaaaaagtt tgggattggc tctagcggta gtgttgttct
    10741 cttaacgcta agagcgttgg cggcctatta tcaggttcat ttgctgccag agcagctctt
    10801 taagctggct gcttacaccc tgcttaaatc aggagataat ggctccatgg gggatattgc
    10861 ctgtattgcc tatgagagtc tggttgctta tacctccttt gataggtgta aggttagtca
    10921 atggttgaca gagatgaccc taaaagagct aatggcagca cattgggggt atacgattga
    10981 gactattgag cctgctctgc cctgttggtt tcttgttggc tggacaaagg ttccttctat
    11041 ctcaagagag atgattcagc tggttaacaa gaacattagc tatccgtttt tagagcaaag
    11101 ccaaaaagtc acacaggagg tgatgactgc cttgcagctt ggtcaaagcg agaggctcaa
    11161 ggctggtatt gaaaaagcga gtcagttgct gcaagggttg gcttcagtta tttatcaccc
    11221 taagcttatg cagcttgtcc aggcttgtca agggcttgat gctgctgcca aatcatcagg
    11281 ctcagggggt ggggattgtg gtattgcact cgtttttgat accaaggaca ttgagcctat
    11341 ccttgccaga tggcagcagg cagggatcgt attactttat caggaggaat ggggatagac
    11401 atgactaatc gtaaggatga ccatatcaca tatgctttga gctatcattc tccttacaat
    11461 gcatttgacg acatggagct cattcactgt tccttgccga gctatgattt agctgatatt
    11521 gatctctcaa cccattttgc tggctgtgat tttgagtttc ctttttatat caatgcgatg
    11581 acaggtggta gcaagaaagg tcaagcagtc aatgaaaagc tggccaaagt ggctgcggct
    11641 acaggtattt taatggtgac aggctcttac agtgcagcct tgaaaaatcc tgaggacact
    11701 tcctttcaat tgcgaggtgt agcaccagat ttacagttgg ccaccaacat tggtcttgat
    11761 aaggctgttg acctagggat tagagctgtc gaggaaatga agcccttgtt tttacaggta
    11821 catgtgaatg ccatgcagga gctgttaatg ccagagggag agcgcagctt taagcattgg
    11881 aaggatcatt tagcggccta tgccaagcag cttccagtcc ctttgatttt aaaagaggtt
    11941 ggctttggca tggatattaa gaccatcact atagcacgtg atatgggagt aaaaaccttt
    12001 gatatttcag gaagaggagg aacctccttt gcctacatcg aaaatcaaag aggaagtaat
    12061 cgctcttacc tagacgattg gggacagaca acagtgcaat gtctattaaa cgccaaaggt
    12121 ctggttgatg aagtggagat cttagcctca ggtggtgtca gacacccctt agatatggtt
    12181 aaatgcttgg tgctgggggc acgtgctgtg ggcctatcgc gagtggcatt ggagttagtt
    12241 gagacctatc cagttgagca ggtcatcgct acgatcaaca gctggaagaa ggagcttaag
    12301 ctcatcatgt gtgccttgga ttgtcgaacc ttgagcgatt tgcgtcaggt ggattattta
    12361 ttatatggca gactttatca ggcaaaccgc taaaggcttt ttagttctga gctagctttc
    12421 cttagaaaat catcacaagg gttaatcaac tgcctgcttg gtaattcagc tgattatggc
    12481 tagtaaggtt cttagatgtc tgaatgaatg ataggacaga tgacatagta tagcgctaac
    12541 ctttagtgaa aatcagttcc tggtcaggtt actgagactg aggttaagtc tatgcttaca
    12601 ttaacatcta aagaatatga aaacacttgg tagctgccat taaagctgtt accaagtgtt
    12661 ttttagtcta tgattgattt agtcgtatgg ctattaagag ctgctttgcc ttttccagat
    12721 tcattggctt atcctttagt aaagccttga ctagttgagg cacctcctgc tcactagcac
    12781 ctgctaacag agctagtgac ttagcctgca gcttcatgtg accagcctga ataccagttg
    12841 aggtcaaggc ctttagagca gcaaaatttt gcgccaaccc aactgcggtg atgatttggg
    12901 cgagtacctt ggcatttggt tgctctaaaa ggctgcgagc aacattgaca gttgggttga
    12961 gaccaatcga gcccccttta ctggcaatgg gcattggcag tgttaactct ccacataagc
    13021 tatttttaga tgtatcaacg tgccagctac ttagtcctct ataagcgcca ttccttgcgg
    13081 cgtaggcatg tgctccagcc tcaatagctc tccagtcatt tccagtagct atagctactg
    13141 cgtcgattcc attgaagatt cccttattat gcgttgctgc tcggtaaggg tcaatctgcg
    13201 ctagtttact tgccagttct atttttttgg ctaattgctg ggcttcttcc ttatgtcgac
    13261 ttaagtatct gaggtcaacc tgacacctag cactaactaa agcttttgtt gcatagtttg
    13321 agaggatagc cattaagcat tgaccaccgc ttagggcctc caaatcaggt actaaagcct
    13381 ccatcatcgt attaacgatg ttggctccca tagcctcttg ggtatcaacg ctcagataga
    13441 caatgaaaaa atcctcctta cgctcaacag taaggctctt tgcaccacca ccacgcttaa
    13501 caatagaagg gtaggcattg tttgcaatat caatcaatgt atctgcgtta gctagaatag
    13561 ccagcctagc ctgctcgtca tctttaacat cataaagagc tacctgccca agcatttgac
    13621 gactgagtac ctcagtctga aagccacctg atcgcttgat gattttggca gcaaaggaag
    13681 cagcagcaac aacagaaggc tcttcagtca caaaggggac ctgataggta tgcccattga
    13741 tcagaaaatc aggggctaga ctaaaaggca gagccagtcg accgatgaca ttttcagtca
    13801 tttgattggc aatagcaatg ggtaagagct ggtctgtctc taacagcttt tgctgctgcg
    13861 ggccaagcag ctggtcatct gcgagctgtt gaatgcgttc tgcaaggctt tttttataaa
    13921 agccggccca atttggttta gtttttgtca tcatcttgat aaattcgttg gtgttcctta
    13981 atttctttga gggcaaacct gccagttaga tatggtgaaa agctggcatt gccatcttgg
    14041 tctagtctag gctcttcata aaaaagtgct tcataatcag ccactgaaat cacctgacgt
    14101 tggtctaata gggcttgtcg attagtcagt agcatgtcct tgtaaccgtc aacaagctgc
    14161 cctgaaaaca actcactaac agctcctgag ccatagctaa acaatccaat cctatcacca
    14221 gcccttagca cctgactatt ctctaaaagt gataataagc cgaggtagag tgagcctgtg
    14281 taaatgttgc cgatttgctt gctgtaggca atagaagctt gaaagttttc gtagagtttt
    14341 tctttgtggt tatctgctag tagcgatttt gtcatgatct tatgaagccc ctttagagca
    14401 agctttggaa aggggatatg aaaacagata gcagcaaggt ctgatagctc aatgccttct
    14461 ttttcttgat atttgtccca ggttgttttt agggaatcaa ggtactgctt ggtcgaataa
    14521 ataccattga caaatggtgt tgagctgtaa tttggacgcc aaaaatccat cacatcacgt
    14581 gtctgtgcga cattgtcatg atttaactgg agaatacgag gattagtagt aactagcata
    14641 gcaatacttc cagcaccttg tgttggctct ccggcggatc caatgccgta tttggcgatg
    14701 tcactggcaa tgaccaagac cttggaggct gggtgtgcag caacatgtaa tttggcataa
    14761 tctaaagcag cagtagcgct gtagcaggct tcctttatct caaaggagcg tgcaaagggc
    14821 tgaatatcaa gcagctgatg aacgtaaata ctggctgcct ttgattgatc aatgcttgat
    14881 tcggttgcta aaatgaccat gtcaatgctt gctttatcgt ctttggtaag gatttggtca
    14941 gcagctgatg cagcaagcgt tacaatatcc tctgtaacag gtgcaatgct tagagcgtca
    15001 agcattagcc cctgatgaaa ttttgctgga tcagtgctgc gagcaagtgc caggtcttcc
    15061 atttttaaga cgtattgact ggtcgcaaag ccaatcttat caattccgat gttcataaat
    15121 atccttcttt tatccatttt atagtcctat ccattttatc atattttctt agaaaattag
    15181 ctgatttaat acgatagttt tatctttcaa accaaaaaca gcagcatata gctttcttct
    15241 ggtatttttg aaggaaatta gataaaataa tatgaactgt gcttacagaa aggggtttcc
    15301 atgacaaaag cagatcagat ttttaaagct aatatcaaaa aaattatgga ggagggagtc
    15361 tttagcgagc aggctcgccc aaggtataaa aatggtcaaa cagccaattc caagtacatt
    15421 acaggtgctt ttgcagagta tgatttgtct aaaggagaat ttcctattac gaccctaaga
    15481 ccaatcccta ttaagtcagc tattaaagag ctattttgga tttatcagga tcaatcaaac
    15541 agccttgatg ttttagaaaa caaatacaac gttcactatt ggaatgagtg ggaggtcggt
    15601 cagacaagaa ccatcggtca gcgctacggt gcaatcgtta aaaagcatga tatcatctca
    15661 aaaatcctca agcagctaga ggacaaccct tggaatcgcc gaaatgtgat ttctctgtgg
    15721 gattacgaag cctttgaaga atcagaagga ctgctaccat gtgcctttca ggtgatgttt
    15781 gatgttaggc gagtagatgg tgagctgtat ttagatgcca cactgaccca gcgttcaaat
    15841 gatatgctag tggctcatca tatcaatgcc atgcaatatg ttgccctgca gctaatgatt
    15901 gccaagcact ttggctggag agctggtaag ttcttttatt ttgtcaataa tttgcacatc
    15961 tatgacaacc aatttgcgca agccaaggag ctattggagc gtcagccagc agcctgtcat
    16021 cccaagcttt tgctgcatgt gcctgatggg acagactttt ttgatataag accagaggat
    16081 tttgagctac aggattatca cccagtgaag cctcagctta cctttgactt agcgatttag
    16141 gcgaaaaaga cgattttttc tgagcatttt gccaagaaat ttgatagaat aaaagaagtt
    16201 catattgagg aaagctagtg atgacaaaga agattattgc catttgggca gaggacgaag
    16261 caggacttat cggaacgtgt ggcaagcttc cttggtacct accaaaagag ctgcagcatt
    16321 tcaaggaaac gacactgcat caagctatcc tgatgggacg agtaaccttt gagggcatga
    16381 agggccgctt gttgccaaat cgtcaaacgc ttgttatgac caaaaacagc cattaccatg
    16441 tggagggcgc tttgaccata accagtgtgc aggaggcttt ggattggtat catgcgcagg
    16501 ataagaccct atatgtgatt ggtggcagca aggttttaga ggcctttgat ggtcattttg
    16561 atgcgatcat caaaacagta gtacatcacc ggtttgaggg tgatacctac agtcctaggt
    16621 tagagctgag tgattttgta gaggagacct ctgtgttgta cccgagagac gataacaatc
    16681 cttacgattt cactgttaca gtattgagac atcgctaata tagggagatg atagtctatg
    16741 cagcgtagta tttttggggt atttacggcc tttttgtgtg cgatttgtgt gttatgtgct
    16801 ataccagcct ttagaaaaaa tcgctatggc ttaggattgc tttttttatt aaatgccttt
    16861 actaacctgg tgaataccat acatgccttt tatggaacac tgttttaagc ttaagagaat
    16921 gaaaagagaa agatagagga atcatggcag gaaatcgtag taacgatatt aaggttcatt
    16981 gctcgttttg cggcaagagc caagacgaag tgaaaaaaat tattgcaggc aataacgtct
    17041 ttatttgtaa cgaatgtgtt gccttatcac aagaaatcat caaggaagaa ttggcagaag
    17101 aggttctcgc tgatctgact gaggtaccaa agccaaaaga gctccttgat attttaaacc
    17161 aatacgtcat tggtcaggag cgtgctaaga gagccttatc agttgcagtt tataatcatt
    17221 acaagaggat ttcatttact gagagtcgtg acgatgatga tgtggatttg caaaagtcaa
    17281 acattctgat gattggacca acaggctcag gtaagacctt tttagcccag actctggcta
    17341 agagccttaa tgttccattt gctattgctg atgcaacctc tttgactgaa gcaggttatg
    17401 tcggagagga tgtggaaaat atccttctga aattaattca agccgctgat tacaatgttg
    17461 aacgtgcaga gcgtggcatt atttatgttg atgaaattga taaaatcgct aaaaaaggtg
    17521 agaatgtctc tatcactcgt gatgtatcag gagaaggtgt ccaacaagcc ttgctaaaaa
    17581 ttattgaggg aacggttgct agtgttccac cgcaaggtgg tcgtaagcac ccaaaccaag
    17641 agatgataca gattgatacc aaaaatatct tgtttatcgt cggaggcgcc tttgatggta
    17701 tcgaagagat tgtcaagcag cgcttggggg aaaagatcat tggctttggg caaaatagtc
    17761 gaaagattga tgacaatgcc tcctatatgc aggagatcat tgctgaggat attcaaaaat
    17821 ttggtctgat tcccgaattt attggacgct tgcctgttgt agcagcgctt gagcagctta
    17881 atactgagga tttgattcgt attttaacag agcctagaaa tgctcttgtg aagcaatatc
    17941 aagccttatt gtcatatgat ggcgtagagc ttgagtttga aaagggtgct ctggaggcta
    18001 ttgcaggcag ggctattgag cgcaagactg gtgcacgtgg tctgaggtct attatcgaag
    18061 aaaccatgct ggatatcatg tttgaggtgc caagccaaga ggaagtaacc aaggtacgca
    18121 ttactaagga agctgtcgag ggccaatcaa agcccgtttt agagatagcc tagggaggta
    18181 tgatgtctga agagcaaatc cttaacacgc ataatgcttc gatattgctt agtgcggcaa
    18241 ataagtctca ttacccacaa gacgaccttc ctgagattgc tttggcaggt cggtcaaatg
    18301 ttggaaaatc aagctttatc aatactatac taggacgtaa aagccttgct agaacctcaa
    18361 gcaagcctgg taaaactcag cttcttaatt tttttaacgt tgatgataag ctaaggcttg
    18421 ttgacgttcc tggctatggt tatgctaagg tatctaaggc agagcgggct agatggggaa
    18481 agatgatcga agagtacctg accacacgac aaaatctcag agcagttgtt agtctggttg
    18541 attttcgcca tgagccgtca caggacgata ttcagatgta tgagtttttg aagtattatg
    18601 agattccggt gattattgtg gctacaaagg cagacaaggt tcctcgtggt cgctggaata
    18661 agcatgagtc tatggttaaa aagtccttaa actttgatca aacagatgcg tttattattt
    18721 tttcatctgt tgagcgtatc ggtatcgatg agtcttggga taccatttta gagtatttat
    18781 aagcatatgg taaaaaattt aagtatcttt tagacaggca cttgtgtctg gtctgagagg
    18841 tgctttttta ttgacaaaaa aacaatttgt tgatgacgag cttgtgttca aaaatgtcag
    18901 tttgctaaaa aatgatgata acaaacaaga cttttatgat ataatgctta gcaggataat
    18961 atggagacat gagaaaaagg tcagagacag ctaatttgct atccctgatt ataactatga
    19021 tgaccagcat tattataata ctcatggtgc tagccattag tagcagcacc taacctatag
    19081 cgttgctttt taggttacaa gcactagcgc taggagtatt ataatatatt tagaaaggtt
    19141 tttttatgac aataaaaaaa tgccctcaaa tacttgccct atcccttgct cttgcagcgc
    19201 tagctagtca ggcgcaagcc gtccatgctc tagagcagca ggagatatcg gtcaagcagg
    19261 ctcaggaatc gagcgattgg tttaatgagg acgaagattt tagagctgtc aagtctaata
    19321 cctctacaga gatagactca acagtgacag atttatttgg tgacgctgag tctaagacta
    19381 aggctggaaa agaagagcta aaagcaccaa gctctaagca agaagcactg ccggcagagc
    19441 ctcaaaaaga aaaggagaca tctgccaaac cgactgacca tgcgacagca caagtggaag
    19501 aggcacagcc tgagcaggac tcagataatc cttggctagc agatgacttt gttactaagg
    19561 gagatacctt ggttgggctg tctaaggcag gtcttgctaa gttatcaaag acacctgtcc
    19621 tgacactacc aaggataggt gctgacaaga cagtgttgac aaggattgct agctttgcct
    19681 ttactccaaa taaatcagta gctattgctg attatacagg cagagcaggt gaacatggcg
    19741 agatcaatca tctggacgtc gaaggcagga atattcttac tgagggagag gattttggtg
    19801 cctatgcgat taaaaagctt gtgattcctg aaggctatct ttttatcggc caagatgcct
    19861 ttaatgacaa taaacagcta gaagaaatca gtctagctga cagcttactc agtatttcag
    19921 attatgcctt tgctcacatg agcctgtcta agcttaagct gccaaaaagc ctacagtcca
    19981 ttggagatca agcctttttt gataatcgga ttgcaggcac tttggtattg ccaaaagctc
    20041 taaagcagct gggagaacgc gcctttaagt ccaatcgtct cactggactt gtctttgaag
    20101 gagaaggctt gtctgtccta aaagaagcag cctttcaaga taatgctttc attagtcttg
    20161 ttatcccaga tagcattcaa gccttagaag aggacgtctt tacaggaaac cttggcgatg
    20221 aagaatacgg taatcatgtc gttttacgaa ccaaaagtgg tcagaatcct tacagacttc
    20281 acagtgccaa tgttcttgtc aatccaagtg atcaggctag aacaccacag ccaccaattg
    20341 attacaacaa gtggctcgca gaagatttta cctatactgg acagatgata actggctttt
    20401 cagctagtgg gctgcgtaag gtcaaacgaa ataagcatct agttctgcct aaggactatc
    20461 aagggcagcc cttgacagcc attgcagata atgcctttag aaatgtcgat tttcatgata
    20521 aagccttgcg taaatacgac ctagaaagag tgacgctacc atctaccatt caaaagattg
    20581 gtgcctttgc ctttcagtca aataatctag aaagctttga ggccagcgag gacttagttg
    20641 acattggtca aggtgctttt atgaataatc gcattgagat cctgaccttg aatgataagc
    20701 tgagggtcat tggagatgcg gcctttcata tcaatcgaat ttatgctatt gttatccctg
    20761 aatcggtcga agtaattggc atttctgcct ttaggcaaaa tggtgctaaa catgtggtgt
    20821 ttatgggaga taagctaaca agcattggag aaatggcttt tttaagcaat actctagagg
    20881 aggtggattt gagcagctta gcagggctta agaccatcgc tgttcaagcc tttgcagaca
    20941 atcacttgag agagcttaag ctgccagata atctgattcg tattcaagca gaagccttta
    21001 aagctaatag gcttcaagga gtgactgttc cagacactgt tattagcatt agctttaatg
    21061 cctttgataa taatagtgat gacaaggtga tcctaaggac catcaaccac aataaaaacc
    21121 tgctagctga cggggatggc tttattgtgg atccagacct attaagtgcg gatcaatcat
    21181 ctgttcaagc agttttagag gacctgcagc gcttagatct agctagtcta cgtgctgata
    21241 cagcagctca ttttacaaca ctcatcacaa gaggtaagca gctactaaaa gaatccgctg
    21301 tacggttagg ttatcagctt aggttccttg cagagtcacg atttttctta gggcgcgtga
    21361 gactggatca gctgattaaa tctgctgata tagccctgtc taaccatcaa gacacaccta
    21421 atgctaagct gttgatggct aagctagaca aggccaagct gcattacaat aatagcgcaa
    21481 tgactgctcc taaaataagt cgcttggaaa aagagctcag cctgttaatt gatcttgtcc
    21541 aaggggtagg cgctatctct aaagcaacaa tgactcaagg tgtctataag cttcagacaa
    21601 ccctacctat tccagagtat tatattgggg ttaatcttta tactgatgat caggggaata
    21661 ttttatttgt gcttgacatg agtgatacga ttgggcaggg acaacttgat gactatggca
    21721 atcctatttt aaatgttgat gaggataatg aaggctacca tgctttggcc attgagtcct
    21781 tagcagatta cgaaggcctt acgattaagg atatattgac caaggagcta aatcaattgc
    21841 ctattcgcga tgtcaagcaa gcaagagagc atcgtgttgg tctttttatg gcaatcagag
    21901 atgctgcaag ggaagctcag cttctactag aaaagcagag caaagcctta tcagaatcag
    21961 ccggcaaatc taatggctca aaagtagctg actcaggact tgagccttct gtgacactat
    22021 caaccaataa gactaagaag ctgttaccaa aaacaggagc cttcaaagaa gcttgggtga
    22081 caatgatcgg aatgcttgtt cttttggcgg ctgccctact taaaggcgat agtcgctaca
    22141 aaaaaagaag taaataggct tgcttagcaa gtacactcca gcaccagtga gacttgatgc
    22201 gcttaaaaag cctatctaat ctagcgatag tattttgcca gtgtgggctg gggcttgagc
    22261 ttcaaaaacc aaaaagcctg aaatgacttt tactagcatt tcaggctttt tttagcttgt
    22321 gattcttttt tgtgtgaagc ttacttctca cttatcgtaa tagtatcttg atcaaggctt
    22381 gctaataggt gtttagcagt cgggtgatcc aggtagtaat ccgtaatgcg gtcacgaatt
    22441 tcttgttcga tgacacgtct aagtggacga actcccattg catgatcata gcccagatca
    22501 atcaaacgct ctttaacatc gtcagtcacc tcaaggctaa tccctttttt agcaagggtt
    22561 tggttcacct ctgctagcat taaagcaacg atttcttgta gatccttttt cgctaaatgg
    22621 ttgaattcga tgacaccgtt gaagcgattc aagaattctg gtctaaagta aggtgcaata
    22681 cgctccatga tagcaggctc ttgatcagca ctatctcctg cttgatggcc aaaaccagca
    22741 ttagaggttg cgatgataac cgtatttttg aaattgatcg tgttgccttg tccatctgtc
    22801 aatcgcccat catcaagcac ttgaagaagc agtgtaatga cctgtgggtc tgctttttcg
    22861 atttcatcaa gcaagatgat agagtaagga ctgcgacgga cacgttctgt aagggtattt
    22921 tgattatcat catagccaac atagccagct gttgttccga ttaatttgga aacagctgtg
    22981 cggtcactat attcagacat atctaagcga atgatagcgt cctttgagcc gaacatatca
    23041 agggctaact gcttagccag ctcggtctta ccaacaccag ttgggccaac aaagaggaag
    23101 gagccaattg ggcgattacc gtcatcaaag cctgcgcggt tgcgtcgaat cgcacgagca
    23161 acagcctcaa ctgcaccatc ttgtccgata acatggcctt taagacgatt actgatttct
    23221 ttgagccttt ctaaatcatt agcccccata tttgagactg ggacaccagt tagtcgttca
    23281 acagattctg caatatcatt gacggtggca gtgacctttt gcccttcact gtgatgattg
    23341 atttgctttt gaagctcctc aatgcgtgtc ttagcagtta aggccttttc aaagtcttct
    23401 tctgcaacag ccttttcctg tagctccttt tgcttagcga tttctgcttc aagtgacttt
    23461 agatcagtga cagggtgctg agctgctagg tgggcagccg tcatatcaac aaggtcaatg
    23521 gctttatcag gcaggcttcg ttgtggaata tattggatag cataatcaat agctgccttc
    23581 aagacagagt ctggtaggat cacattgtgg tgctgctcgt agaggttgcg aatgcccatt
    23641 aaaatgtgga aggtatcctc tgctgaagga gcattaacct taacctcgtt gaaacgacga
    23701 gcaagggcag cattttttaa aatagtattg cgatactcat cttgagttgt ggcaccaatc
    23761 aaggtcaact caccgcgtga gagagctggc tttagaatat cagccaagcc cttagagcct
    23821 gagtctgaac cagctgaccc tgcaccaagg atttgatgaa tttcgtcaaa gaagagaatg
    23881 atattgccag cctccttaac ctctttaacc atgttttgaa tgttttcttc aaaagagcca
    23941 cgatactgtg tgccagcctc aaggccagaa atatcaattg agataatctc tttatttttg
    24001 atggcagctg gcacatcacc gttgacaata gcctgggcta ggccttcgac aacagcagtt
    24061 ttaccaacac cagcgtcacc gacaagaaca gggttattct tggttcgtct tgctagaatt
    24121 tctgcggtcg cttgaatctc atcgtttcgt ccgatcacag gatctaacct gccttgccga
    24181 gcttcttcgg tcaggtttgt tccgagcttg gttagaatgc cgtctttttt aaggctgcta
    24241 gcctgttttt cttgtccctc agctacagct agcttaccgg ttttccggta ttcttgaaat
    24301 tcctctggtg tcatctcacg tccattgaca agatagcgac gattttcgct gcggtagccg
    24361 ccgatgtttc ccattaattg attaaaaata tcgtccatat ttccaaaggg gtcttttcca
    24421 taataggttg ccatatacac ttacctcact tgtattatat ttaccagtca ttatgagcta
    24481 ctggtatagg tagaaggtga tcggtgttgg ctcatacaga gatcatagag aggtcttatg
    24541 agagtctatt gctcaggctt attactcacc ttctaataat attatatcca aaaggtcagt
    24601 aaaggtcaaa taaaaagtat gaataattaa cctttataat caggtgctta tagcccttga
    24661 aacatcagat gactatgcca taagctgctg gtgctttttt gctagcaagg ctatctgtaa
    24721 agaagagact tttgtcaaaa atggttttac tttttgttct aaaggctttc atgatataat
    24781 aaaagaaaag cacagaggtc aattatggaa caaacatttt ttatggtgaa gcctgatggt
    24841 gtgaaacgtg gcttggttgg agagattcta cgccggattg agcgtcgtgg ctttaccttt
    24901 gataggcttg aattgcgaca ggcaactcca gaattgctag ccaagcatta tgacgcctta
    24961 atcaataagc ccttttatcc agagctagag gcctatatga caagcggacc tgttttaatc
    25021 ggcattatct ccggtaatcg tgtggtctct tcctggcgaa ccatgatggg ggtgactaat
    25081 cctaaggacg ctttaccggg gactattcgt ggtgattttg ctcaagcccc tggtgatgat
    25141 ggcggcattt ttaacgtggt gcatggttcg gattcgagag attcagctaa gcgagaaatt
    25201 gcgatctggt ttggacatag ctgacattgg gcttgggtct attcttttaa gaactgataa
    25261 agcaattgca taaggggttg gtaaagccca tcatcaatag tagctcagca ttagaagggt
    25321 aacagccttg atgttgggct atttttttgc ttgcctaggg tttatatgct tgtcctgatg
    25381 agcaggtaga caaagcagca taagtttaac aatcctttgc ggcagtgatc aattgtagct
    25441 ctaaccatag catcagctat ttgaaagcct tgaaaaagaa agctaaggct aacaagctag
    25501 tctaggtcat ttactacaag cgactttttc aattagctgc tcaaggcaag tattgaaaaa
    25561 agtccatttt tcatgtcatt tgtaataata tggtatattt ttaacgaaaa gtcgttttag
    25621 ttgagaaaat atacaaaaaa ggctatgata tagttaataa agttgttata ccccctgtgt
    25681 cttgtacact atgacttgta gagagtttat caaaggagga taagatgaac aaacaaagca
    25741 tgacccattt ttctaagaag ctgatgaagc tagccctttt aggcttggca ttgccattaa
    25801 gcttggtgtc ggtggcagat actccggttc ttaaccgatc cgaaaaagct gtttatgcca
    25861 atgattttgg atctggaaat cgagccagtg attatgtacc ggcggctaag gcttggagct
    25921 ttgaggctta tccagattac taccgcgttt taggggctag tcatcttaat cctgcaatct
    25981 ttccagaagc tggcaacatg tcctatagtc ccttagatga attgggacgt acacaggtcg
    26041 ccagaggaac aataaattat cacaatattg tgatgaacta caatgttaga cagcgctttg
    26101 ctaaaaatca gaacccttca ggctggattg gtaaccctag aaatgttcgc tacactattg
    26161 agtggctaga tggcctatcc tatcagggag atttttggaa tcggagtcat ttgattgcag
    26221 atagccttgg tggagcagcc ttacgtgtca atgcgattac tggtacaaga acacaaaatg
    26281 ttggcggcag aaatcaaaga ggcggtatgc gctatattga gcagaaggtg cagcagtgga
    26341 ttgagcagca tacaagcgca gttgtttatt acgaagcgat gccaatttat caggcaaatg
    26401 agctagttcc aagagctgtt gttgtttcag cattgtcatc agacggaggt cttgacgaaa
    26461 aggtcatggt ctataatacc gccaacggct ataccatcaa ttatgctact ggagcatttc
    26521 aaagtaatta ggcttttgta ctaagctgta gctgatcaag gtctgactaa gacaagtgca
    26581 tcagcaattg atatataaaa agacatgaca gcagctgttt taaatgcctt gtcatgtctt
    26641 tttagtcttg tcagcttttc atgttgtctt aaaatgacca ctcaactaac tacaagcatt
    26701 gacccaaaga agagttaagg atagctaggt gctaaagcta gctaggtgcc ttttagtcag
    26761 aggtatggga ctgctagcta atataatgcc cgcagttgag ccaatttctc atctaggcta
    26821 atacaggcta ttgacttata gtgttcatta gaatgtcagc tgttgtagtt ggtagtattc
    26881 gaatacgatt aagcgatagc aggccattag cagcacttgc tagtccttca tttgttgtga
    26941 cccctaactt gtaatgcagg tcctcagcaa tctttaatgt ggtatcagta tagcgacctg
    27001 ctggataggc aattgcaatc gtatcttggt gcagctctct atctaggtat tctttagaat
    27061 ccttcatttc agcggtttga ctagcagcgc ttgcctgaga tagatcaggg tggttaaccg
    27121 tatgatcttg gaaagacatg cctgcctgct tcatttcctt catctggtct aatgtaagat
    27181 tggctgcatt acctgcctct gtaaagccag tgatgacgtt attggtggcc ttgatgccat
    27241 gctttttcag gattggaaaa gcaacgttgt aaaaatcaac catgctatca tcaaaggtta
    27301 gccagacaac cttttcagca ggaagttcgt tagctgataa gactcggtag gcttcttcgg
    27361 gagataaaaa gtagtagccg gcctccttca ttgcctttag ctggctttca aaaagatctg
    27421 gagcaacgat gagattagca cttgctgcct cttctggtgc cataacgtga atagcatgat
    27481 acattaaaat agga
//
LOCUS       DARYSY010000195        11667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.guided.056, whole genome shotgun sequence.
ACCESSION   DARYSY010000195 DARYSY010000000
VERSION     DARYSY010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11667
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.guided.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            <1..1298
                     /locus_tag="TVR04_002084"
     CDS             <1..1298
                     /locus_tag="TVR04_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1270728.1"
                     /translation="NGGHILLGVNDKREIVGVSKDKVDKVIKEFTTAINNSQKMYPPL
                     YLLPEVFDIDEKKVIYIRVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQ
                     GSYFVNKVYPNLDIDFLDASVIDKAKKMAVSRNKNHVWENMSNEELLRSANLILTDPE
                     TKREGITLAAILLFGKDNSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRL
                     IEFGQKHLNDLFVLDGIVNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDQRITVE
                     NSNLAHGMGALDLQKFEPFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGENPL
                     FEEGDIFRTIIPLKKIATQKVGGGNVPRNVPQDVSRMSLEEIENIIKDMIKGDNRVSR
                     KDIAMVLGVSEKTITRYIKDIPNIKYVGKGKNGHWELNE"
     gene            1384..8715
                     /locus_tag="TVR04_002085"
     CDS             1384..8715
                     /locus_tag="TVR04_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003034181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1270729.1"
                     /translation="MRINDFHNILELVKQDVLRSEAEYLKFLKVVGNNQRYDFRSQLS
                     IYDRNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDIGQTVSRNR
                     DVNEVNLWRFDKEAHRDVLKEMIVSEGYEESESILENIFSLSRLYGDEKIDSLMNELR
                     IADEDRISFTKFVRDSVSYAVASRFKVDYPVDNELLKENFAKLDRISLMSLGETVSDI
                     SGKIIDETIQKSKEMELQKEVLRGKEAGYNRIKEELEEVEENVLRRDDQKRNESGRVL
                     RNGEYGRDNRENQGEYAKQLGGTDGLHKGVSESDLRSDEAGLPFTERGAEPLRDVGRS
                     IQGEEANRTPDRYSETGNRIYENGEGEIDGSLEDRGREQSTVWGDDFGSEGNDNQGSS
                     GNLKDNTNVELKEAEKASFSLPENFYGQMRLTIPLNQKDIDTILINGGNHDGGRLPLI
                     AEFSKGKSNGELGEYLKDTFKGGNGFYIDEREVSSWYSDKGIHLSYGTSAREDDTQIL
                     SWSNAASRINELLETGEFATNVELFEALDYERDRISESLWYLYHDLSEEGKAQGYFDF
                     IERGGGFPEETKRLSEALKNPEYLKETIKEYSRFLEGYKENRNVLRFHYHKVDSLYQR
                     LQELKLSRKEYSTNLTELPKVKSFITEDEVKATISRGSGIDKGKERITKFFKENHTLQ
                     EKAHFLKDEYGIGGRSHAVSGAMGSDEWHDAKGLKLQKKDCSNVFLTWSSVAKHIDEL
                     LSKNLYEEKKIESKAEIEKAKAPQYYSKDDPENLMTDEMLERVPELYSQEDVALADKE
                     VHAAYIIPFRLNWTWYMTEYDRESGDAFGLVLGFEPEWGYFNLEELKELNAQRLILED
                     FPKTFRELKDTELKKQMDEQELQAIFNGELSFEDKEELEISEEVEERVAVTPVQGTLF
                     DYLKEREEVELNEEKESRADESEIKEGDTVYFNHEEYTVREISKNKITGRNDLWLDPV
                     RSGNHQIPIVAFTDNEDLLRQISPERPVFIVGDEIKYKDKDYTITRFDDMGNNLKTVT
                     VKDNTEYLGGMITGSDVIPYRLENDLERVFENLTYKKPETITKESEIKKIEAHNFKIT
                     EETLPEKLSPSERLNNNLEAISMLNRVENGQRELDSTAQEVLARYVGWGGLADVFDEE
                     KGGQWKEARSFLKENLSQAEYEAARESTLTSFYTPKTVIDGVYKTLSDMGFKQGNILE
                     PSMGIGNFIGNLPDEMRRSKFYGVELDSISGRIGKLLYPESDIQIKGLEETSFSNNFF
                     DAVIGNVPFGEYKVNDREYNRNNFLIHDYFFAKSIDKVRNGGVIAFITSSGTMDKKDE
                     SVRRYLAARAEFLGAIRLPNDTFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHLAEDE
                     NGLVYNKYFVDHPEMVLGSMEEVSGRFGKTLTCEPIAYLGTELNMASLKERIEIAGER
                     ISKDAKYEEIELLDDEITSIPATDDVKNFSYTIIDDEVYFRENSIFVKKEVTDKNKEK
                     IKDYLELNEALKDVIYKQKEDFSDDEVKKSQEKLNEIYDSFSKKHGYVNNLSNTRALK
                     EDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKVIDHVDTSLEALVLSVSEKGYV
                     DFEYMGSLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSY
                     KYGYVTKDEYLSGNIRDKIAIVDSYLAKLRQTERELPHLGYAEDGKEKELISYEMNRL
                     EYQKAELTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGWARWDIKVKFSN
                     LTSEWNVEGKSKDRGNDLAEMTYGTSRVNAYKLIEDALNLKETKVFDQIVNPDGSKTS
                     VLNKKETMLAGQKQELLKEEFKNWIFSDQERRNRLVKLYNERFNSIRNREYDGSKLSF
                     EGMNTKIELRPHQKNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLF
                     VVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGRIATGEYDAVVIGHTQF
                     EKIPMSKEYQEKHIQDQIDEIINYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDD
                     FKKDDVITFEELGVDKLIVDEAHNYKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYM
                     DEMTNGKGIVFATGTPVSNSMTELYTMQRYLQYDDLKKNGLEHFDSWASTFGETQSAF
                     ELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEAHYEVIKTLPSE
                     EQKEILKSLSERADDVRNRVVEPDEDNMLKITNDGKKLALDQRLINPLLPDNPDSKVN
                     VCVKNVFAIWDKTKEDRSTQLLFSDMSTPKGDGEFNIYDDIRDKLVAMGIPKEEIAFI
                     HEANSDKQKDELFAKVRKGDVRILLGSTQKMGAGTNVQNKLIALHDLDVPWRPADVGR
                     ILRTFKIKKNVEVTDNGKDNF"
     gene            8696..9070
                     /locus_tag="TVR04_002086"
     CDS             8696..9070
                     /locus_tag="TVR04_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1270730.1"
                     /translation="MAKTIFEEMGGKYERQGDYLIPCLTVPAEEEQPIGIWGQRHLDY
                     LKHHCKVTYTNLLTSGRLNAYLADIDRQAQERFERLIEGMKQAQGITEQLKAENALEW
                     TGCLNNIRACAREIVEKEIIFA"
     gene            9437..11356
                     /gene="tet(O)"
                     /locus_tag="TVR04_002087"
     CDS             9437..11356
                     /gene="tet(O)"
                     /locus_tag="TVR04_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HEL1270731.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRKFIENPLPMLQTTIAVKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     NVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQVKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPAIGKFICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            11408..11581
                     /locus_tag="TVR04_002088"
     CDS             11408..11581
                     /locus_tag="TVR04_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002779755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEL1270732.1"
                     /translation="MMKCEWILCPVCGSKTRNKIRKDTVLENYPLYCPKCRQESLIKV
                     DNLKITVIKEPDA"
BASE COUNT         4158 a         1764 c         2678 g         3067 t
ORIGIN      
        1 gaaatggagg acatatttta cttggtgtaa atgataaaag agagattgtt ggtgttagta
       61 aagacaaagt tgataaagtg attaaggaat ttactacggc aatcaacaat tcgcaaaaga
      121 tgtatccacc actttatttg ctacctgaag tctttgatat agatgagaaa aaagtaattt
      181 acatcagagt gccggaaggc tatcaggtgt gcagacataa cggcagaatt tgggacaggt
      241 cttatgaagg agacatcaat atcacagatc attctgaact tgtatataag ttatatgcaa
      301 gaaaacaagg aagctatttt gtaaataaag tatatccgaa tcttgatatt gattttcttg
      361 atgcttctgt cattgataag gctaagaaaa tggctgtttc ccgaaataaa aatcatgttt
      421 gggagaatat gagtaatgag gagcttctta gaagtgcaaa tctcattctg acagatccgg
      481 aaacaaagcg tgaaggaatt acattagctg ctattttgtt atttggaaaa gacaactcta
      541 tcatgtccgt tcttccacag cataaaactg atgcgatatt tagagttgaa aacaaggata
      601 gatatgacga tagagatgtt gtcataacaa atctgattga tagctatgac agacttatag
      661 aatttggaca gaagcatttg aatgatttat ttgtcttgga cggaattgta aatgtcaacg
      721 caagagatag gatactcaga gaaatagttt ccaatacatt ggctcataga gattattcaa
      781 gtggttttcc tgcaaagatg attattgacg atcagaggat tacggttgaa aacagcaact
      841 tggctcatgg aatgggagct ttagatttac agaagtttga gccatttccc aagaatcctg
      901 ctatatcaaa ggtgtttaga gaaataggtc ttgcggatga acttggttca ggaatgcgaa
      961 atacctacaa gtacacacag ctttattcag gagaaaaccc gctatttgag gagggggata
     1021 tattcaggac gattattcct ctaaagaaga tagcgacaca aaaagttggt ggagggaatg
     1081 tccctcgaaa tgtccctcaa gatgtctctc gaatgtccct cgaagaaatt gaaaacataa
     1141 tcaaagatat gattaaaggg gacaatagag tgagccgtaa agatatagct atggtattag
     1201 gagttagtga aaaaaccatt acaagatata taaaagacat tcctaatatt aagtatgttg
     1261 gtaaagggaa aaatggtcat tgggaactga atgaatagaa ttaagttgca atacacagaa
     1321 tttaaaggtg attagagtaa aatctaacca ccttttttgt ttggaaaaaa gaaggaggta
     1381 aaaatgcgaa taaatgattt tcataacatt ttggagcttg taaaacaaga tgttttgcga
     1441 agtgaagcag aatatctaaa gttcctcaag gttgtcggaa acaatcagag atatgacttt
     1501 agaagtcagt taagtatcta tgatagaaat cctgaagcga cagcctgtgc caagttcgac
     1561 tattggaggg aacgatttaa ccgtaccgtt atgagaggtc aaaagggtat cccaattttg
     1621 gaggactacg gcacatacaa aaaagtggac tatatctttg atataggtca gacggtttca
     1681 agaaacaggg atgtcaatga agtaaatctt tggagatttg ataaagaagc tcatagggat
     1741 gtcttaaagg aaatgatagt aagtgaaggt tatgaggaaa gtgaaagcat cttagaaaat
     1801 atcttttctt taagcagact ttatggtgat gaaaagatag acagccttat gaatgagctt
     1861 agaatagcag atgaagatag aatatctttt actaaatttg tgagggactc agtgagttat
     1921 gcagtagctt caaggtttaa ggtagactat cctgtggata atgagcttct aaaggaaaac
     1981 tttgcaaagc ttgatagaat ttcccttatg agcttaggcg aaaccgtatc ggatattagc
     2041 ggaaagatta ttgatgaaac cattcagaaa agcaaagaaa tggagcttca aaaagaagtt
     2101 ttaagaggaa aagaagcagg atataatagg attaaggaag aattagagga ggtagaagaa
     2161 aatgtacttc gacgagatga tcagaaaaga aatgaaagcg ggcgagttct ccgaaatgga
     2221 gagtacggac gagataatag agaaaatcag ggagaatacg ctaaacagct tggaggaaca
     2281 gacggacttc ataagggagt atccgaatcc gacctacgca gtgatgaggc tggattacct
     2341 ttcacagagc gaggagcaga gccgcttcga gatgttggta gatctataca aggagaagaa
     2401 gctaatagga cacctgatag atattcagaa acaggcaata gaatttatga gaacggagaa
     2461 ggcgaaattg atggcagctt ggaagataga ggacgagaac aatccacagt atggggcgat
     2521 gatttcggct ctgaaggaaa tgacaatcaa ggaagtagtg gaaatttaaa agataatact
     2581 aatgtagagc taaaagaagc tgaaaaggct tctttttctt tgcccgaaaa tttttatgga
     2641 cagatgaggc ttactattcc tcttaatcag aaagacatag acactatcct tattaacgga
     2701 ggaaaccatg atggtggtag gcttcctctt atagcagagt tttctaaagg aaaaagtaat
     2761 ggagaattgg gagaatacct caaagataca tttaaaggag gaaatggatt ttacattgat
     2821 gaaagagagg tatcttcctg gtattcggat aaaggcattc acttatctta cggaacatct
     2881 gcaagagaag atgatacgca aattttaagc tggagtaatg cagcaagcag gataaatgag
     2941 cttttggaaa ccggagagtt tgccacaaat gtggagcttt ttgaagcctt agattacgaa
     3001 agggatagaa tttcagagtc attatggtat ctataccatg atttaagcga agaaggaaaa
     3061 gcacaaggtt attttgactt tatagaaaga ggtggtggtt ttccggaaga aacgaaaagg
     3121 ttatctgaag cattaaaaaa tcccgaatac ctaaaggaaa cgatcaaaga atacagcagg
     3181 tttttagagg gatacaaaga aaacagaaat gtattaaggt ttcactatca caaggtagac
     3241 agcctttatc agaggttaca ggaactcaag ctgtcacgaa aggaatacag taccaatctg
     3301 acagaacttc ccaaagtgaa gtcctttatt acagaagatg aagtcaaagc tactatttca
     3361 agaggaagcg gaatagataa gggaaaagag cgaattacaa aatttttcaa ggaaaatcat
     3421 acgcttcaag aaaaagctca cttcttaaaa gatgagtatg gcatcggtgg tagaagtcat
     3481 gcagtatcag gtgcaatggg aagtgatgaa tggcacgatg caaagggact taaattgcaa
     3541 aagaaagatt gcagtaatgt gtttcttact tggtcaagtg tggcaaagca tattgatgag
     3601 ctgctttcta aaaatctgta tgaagaaaag aaaatagaaa gtaaggcaga gatagaaaaa
     3661 gcaaaagcac cacaatatta ttctaaagat gatcctgaaa atctaatgac cgatgaaatg
     3721 cttgaaagag tccctgagct ttattcacag gaggatgtag cattagcgga taaagaggtt
     3781 catgcagcat atatcatacc ttttcgttta aactggactt ggtatatgac ggaatatgac
     3841 agggaaagcg gtgatgcctt tggacttgtg ttaggatttg agcctgaatg gggatatttc
     3901 aatcttgaag aattaaagga gttaaatgcc cagaggctaa ttttagaaga ttttccaaag
     3961 acctttagag aacttaaaga tacggaactt aaaaagcaga tggatgagca ggagcttcaa
     4021 gcgatattta acggagagct tagctttgaa gataaagaag aacttgaaat atctgaagaa
     4081 gtagaagaaa gagtagctgt aacacctgtt cagggaacgc tatttgatta cctcaaagaa
     4141 agagaagaag tagagcttaa cgaagaaaag gaaagccgtg cagatgaatc tgaaattaaa
     4201 gagggagata ccgtctattt taatcatgaa gaatacaccg taagggagat ttctaaaaac
     4261 aaaatcacag gaagaaatga tttatggctt gatccggtaa gaagtggaaa tcatcaaatc
     4321 cctattgtag cctttacaga taatgaagat ttattaagac aaataagccc tgaaagacct
     4381 gtgtttatcg ttggagatga aattaaatac aaggataaag actataccat cacacgcttt
     4441 gacgatatgg gaaataatct aaagacggta acggttaagg acaataccga atatcttggc
     4501 ggtatgataa caggctccga tgtaattcct tatcgtctgg aaaacgatct tgagagagta
     4561 tttgaaaatc tgacatataa aaagcctgaa actattacta aagaaagtga aataaagaaa
     4621 attgaggctc ataacttcaa gattacggaa gaaacattac ctgaaaagtt atctccaagt
     4681 gaaaggctaa ataataacct tgaagcaatt tccatgctta atagagtgga gaatggacaa
     4741 agagaacttg acagtacagc acaggaagtt ttagcaaggt atgtaggctg gggaggactt
     4801 gctgatgtat tcgatgaaga aaaaggcgga cagtggaaag aagcgaggag ttttctaaag
     4861 gaaaacttat ctcaggcaga atatgaagct gcaagagaat ctaccctaac gagcttttac
     4921 acaccgaaaa ctgttattga cggcgtatat aagacacttt cagatatggg attcaagcag
     4981 ggaaatatcc ttgagccatc aatgggcatc ggaaacttta tcggtaatct tcctgatgaa
     5041 atgcgtaggt caaagtttta tggtgtagag cttgacagta taagcggtcg aatcggaaag
     5101 ctgttatatc ctgaaagtga tatacagatt aaaggacttg aagaaacttc cttttccaat
     5161 aacttttttg atgcagttat cggtaatgtt ccctttggag aatacaaagt aaatgacagg
     5221 gaatacaatc gtaataactt ccttattcat gactatttct ttgccaagtc cattgataag
     5281 gttagaaacg gcggggttat cgcctttatt acatcaagtg gaacaatgga taaaaaggat
     5341 gaaagtgtaa gaaggtatct tgcagcaaga gcagagtttt taggagctat cagacttcct
     5401 aatgacacct ttaagggtgt tgccggcaca gaggtaacaa gcgatattat cttcttaaag
     5461 aaaagagata gcgtattaga gcgtgatgaa gattggatac accttgcgga agatgaaaac
     5521 ggtcttgtat ataacaaata ctttgtagat catcctgaga tggtgcttgg aagtatggag
     5581 gaagtatcgg gaagatttgg aaaaactcta acttgtgaac cgatagctta tttaggcaca
     5641 gagctaaata tggcttcatt aaaggagcgt atcgagattg caggagaaag aatttcaaaa
     5701 gatgccaagt atgaagaaat agagctttta gatgatgaaa tcacttcaat ccctgcaacg
     5761 gatgatgtta agaacttttc ctataccatt attgatgatg aggtctattt cagggaaaat
     5821 tccatatttg taaagaaaga agtaacggat aaaaacaagg aaaagattaa agattatctt
     5881 gaactgaacg aagccttaaa ggatgttatt tacaaacaaa aagaggattt ttcagatgat
     5941 gaggtaaaga aatctcagga aaaattaaat gaaatctatg acagcttctc taaaaagcat
     6001 ggatatgtca ataacctttc taataccaga gccttaaaag aagatagcaa ctttcctttg
     6061 gtatcatcta ttgaaattct tgatgaagaa gaaaacttca aagcaaaggg cgatattttc
     6121 agtaaaagaa caatcacaaa ggctaaagtc atagatcatg ttgatacttc tttagaagcc
     6181 cttgttttat cggtatctga aaagggctat gtggattttg aatatatggg aagtcttaca
     6241 ggaaaagaca gaccgacttt gattgaggaa cttaggggag agatttatct aaatatcaga
     6301 gaggaacaaa acttttacag accactgtct tttaacttgg aagatggaga tttacctttt
     6361 gcctgtgcca atggtagcaa ttcctataaa tacggttatg taacaaagga tgaataccta
     6421 agcggaaaca tcagggacaa gattgccata gtagacagct accttgcaaa gctaagacag
     6481 acagaaaggg aacttcctca tcttggctat gcagaagatg gtaaagaaaa agagctgatc
     6541 agctatgaaa tgaatcgttt ggaatatcaa aaagcagagc ttaccaaagt tttaccaaag
     6601 gagcttgaag caagtgaaat caatgtaagg cttggtgcga catggatacc gattaaggat
     6661 attgaaaagt ttatttttga aacacttaaa acaccgggtt gggcaagatg ggatataaag
     6721 gttaaatttt caaatttgac aagcgaatgg aatgtagagg gaaaaagcaa agacagagga
     6781 aatgatcttg ctgaaatgac ttatggtaca agtagagtaa atgcctataa gctgattgaa
     6841 gatgcactga acttaaaaga aacaaaggta ttcgaccaga ttgtaaatcc ggacggctcc
     6901 aaaacttctg tactaaataa aaaagaaacc atgcttgcag ggcaaaagca ggagcttcta
     6961 aaagaagaat ttaaaaactg gatatttagc gatcaggaaa gaagaaacag acttgtaaaa
     7021 ctgtataatg agcgttttaa ctctatccga aatcgtgagt atgacggaag taagctatct
     7081 tttgagggaa tgaatacgaa aatagagctt agacctcatc agaaaaatgc tattgcaaga
     7141 agtttgtatg gtggaaatac gctgcttgct catgtggtag gtagtggaaa gacttttgaa
     7201 atggtggctt ccgcaatgga atctaaaagg cttgggatgt gttctaagtc tttatttgtt
     7261 gtaccgaacc atctaacagg acaaatcggc agagagttta tgcagctcta tccgtcagcg
     7321 aatatcatgg tggcagataa gaaagacttt gagccgaaaa accgtaagcg tttcatcggt
     7381 agaattgcga cgggagaata cgatgccgtt gttatcgggc atacgcaatt tgaaaaaatt
     7441 ccgatgagta aggaatatca ggaaaagcat attcaggacc agattgatga aatcataaac
     7501 tatgttgagg aatataagca tgatagaaat cagaacttta cggtaaaaca gcttgaaaag
     7561 acaaagaaaa aacttgaaac aaggcttgaa aaattaaatg atgattttaa gaaagatgat
     7621 gtcattacct ttgaagagct tggcgtggat aaactgatag ttgacgaagc tcataactac
     7681 aaaaaccttt atctttatac aaaaatgaga aatgtagcag gtatcgggca gtctgaagcc
     7741 tttaagtctt ccgatatgtt tatgaagtgc cgctatatgg acgagatgac aaacggaaaa
     7801 ggtatcgtat tcgctacagg aacacctgtc agtaactcga tgacggagct ttataccatg
     7861 cagagatatt tgcagtatga tgatttaaag aaaaatggct tagaacattt cgactcctgg
     7921 gcttctactt ttggagaaac gcagtcagct tttgagcttt ctcctgaggg aaccggatat
     7981 agagtgaaga caagattttc taagttctat aatcttccgg agcttatgag tatgtttaag
     8041 gaagtggcag atattcaaac agcggatatg ctgaatcttc caacacctga agcacattat
     8101 gaggttatca aaaccttgcc aagtgaggaa caaaaggaaa tcctaaagag cctgtctgaa
     8161 agagctgatg atgtcagaaa cagagtggta gagcctgatg aagataatat gctgaagatt
     8221 accaatgacg gcaagaaact tgctcttgac caaagactga tcaatcctct gctacccgat
     8281 aatcctgaca gcaaggtcaa tgtatgcgta aaaaatgtgt ttgccatttg ggataagaca
     8341 aaagaagata ggtcaacaca gcttctattt tccgatatgt caactccaaa aggcgatgga
     8401 gagtttaata tctatgatga tattagagat aaacttgtgg caatggggat accaaaagaa
     8461 gaaatagcct ttatccatga agctaattcg gataaacaaa aagacgaact ctttgcaaag
     8521 gtaagaaagg gagatgtgag gatattactc ggttcaactc agaagatggg agccggcaca
     8581 aatgtgcaaa ataaactgat tgcacttcat gaccttgatg ttccttggcg tcctgccgat
     8641 gtaggacgga ttttgcggac attcaaaata aaaaagaatg tggaggtaac agacaatggc
     8701 aaagacaatt tttgaggaaa tgggcggcaa atacgaaagg caaggcgatt atttaatacc
     8761 gtgcttaact gtacccgccg aagaagaaca gccgataggc atctggggac agcggcattt
     8821 ggattatctg aagcatcact gcaaagttac atacaccaat cttcttacaa gcggcagact
     8881 taacgcttac cttgccgaca ttgacagaca ggcacaggaa cgctttgaaa ggctcataga
     8941 gggtatgaaa caggcacagg gcataacgga acagctaaag gcagaaaacg ccttagaatg
     9001 gacaggatgc ctcaataaca taagggcttg tgcgagggag attgtggaaa aggaaattat
     9061 ttttgcataa acagatgatt agtggcaggg ggaaatcctg ccgctttttc tgctttagtt
     9121 tgtcagcttg acaaataaag ggttaaggaa tataattaga ttcagtatta tacaaggagt
     9181 taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagtg ggaacaaaaa
     9241 gtagcagtcc cgtttcactt ttaatatggg gcttagtttt ttgtacccag tttaagaata
     9301 cttttatcat gtaattttat atgcccgaaa acatataagt gttttggggc tattggagtt
     9361 atttacccag tgataggagt atttatcact gggtattttt atgccctttt ttgggtgttg
     9421 ataggaggaa aatcacatga aaataattaa cttaggcatt ctggctcacg ttgacgcagg
     9481 aaagacaaca ttaacggaga gtttattgta taccagtggt gcaattgcag aaccagggag
     9541 cgtagataaa ggcacaacaa ggacagatac aatgaatttg gagcgtcaaa ggggaatcac
     9601 tatccagaca gcagtgacat cttttcagtg ggaggatgta aaagtcaaca ttatagatac
     9661 gccaggccat atggattttt tggcggaagt ataccgttct ttatccgtat tagacggagc
     9721 agtattatta gtttctgcaa aggatggcat acaggcacag acccgtatac tgtttcatgc
     9781 actacagaca atgaagattc cgacaatttt tttcatcaat aaaattgacc aagaggggat
     9841 tgatttgcca atggtatatc aagaaatgaa agcaaagctt tcttcggaaa ttatagtgaa
     9901 gcaaaaggtt gggcagcatc cccatataaa tgtaacggac aatgacgata tggaacagtg
     9961 ggatgcggta attatgggaa acgatgaact attagagaaa tatatgtcag ggaaaccgtt
    10021 taaaatgtca gaactggaac aggaagaaaa caggagattc caaaacggaa cgttatttcc
    10081 cgtttatcac ggaagtgcta aaaacaatct ggggattcgg cagcttatag aagtgattgc
    10141 cagtaagttt tattcatcaa cgcctgaagg tcaatctgaa ctatgcgggc aggtttttaa
    10201 gattgaatat tcagagaaaa ggcggcgttt tgtttatgtg cgtatatata gcggaacatt
    10261 gcatttgagg gatgttatta aaatatctga aaaagagaaa ataaaaatca cagagatgtg
    10321 tgttccgaca aacggtgaat tatattcatc cgatacagcc tgctctggtg atattgtaat
    10381 tttaccaaat gatgttttgc agctaaacag tattttgggg aacgaaatgc tgttgccgca
    10441 gagaaaattt attgaaaatc ctctccctat gctccaaaca acgattgcag taaagaaatc
    10501 tgaacagcgg gaaatattgc ttggggcact tacagaaatt tcagatggcg accctctttt
    10561 aaaatattat gtggatacta caacgcatga gattatactt tcttttttgg ggaatgtgca
    10621 gatggaagtc atttgtgcca tccttgagga aaaataccat gtggaggcag aaataaaaga
    10681 gcctactgtt atatatatgg aaagaccgct tagaaaagca gaatatacca tccacataga
    10741 agtcccgcca aatcctttct gggcttctgt cgggttgtcc atagagccgc tccctattgg
    10801 aagcggagtg cagtatgaaa gcagagtttc acttggatat ttaaaccaat cgttccaaaa
    10861 tgcggttatg gagggggttc tttatggctg cgagcagggg ctgtatggat ggaaagtgac
    10921 agactgtaaa atctgttttg aatatggatt gtattatagt cctgtaagta cccccgcaga
    10981 ctttcggctg ctttccccta tcgtattgga gcaggcttta aaaaaagcag ggacagaact
    11041 attagagcca tatctccact ttgaaattta tgcaccgcag gaatatctct cacgggcgta
    11101 tcatgatgcc ccaaggtatt gtgcagatat tgtaagtact caggtaaaga atgacgaggt
    11161 cattctgaaa ggagaaatcc ctgccagatg tattcaagaa tacaggaacg atttaactta
    11221 tttcacaaat gggcagggag tctgcttgac agagttaaaa ggataccagc cagctattgg
    11281 taaatttatt tgccaacccc gccgcccgaa tagccgtata gataaggttc ggcatatgtt
    11341 ccacaagtta gcttaacagc ttgcaaaagt catataaaat gagatttgaa aggattagag
    11401 actaattatg atgaaatgcg aatggatatt gtgtcctgtt tgtgggagca aaacccgtaa
    11461 taaaattagg aaggacactg ttttggagaa ttatcccctt tattgtccaa aatgcagaca
    11521 agaaagcttg attaaagttg acaacttgaa gataactgtc atcaaagagc cagacgctta
    11581 agacgcagag ccgatgaaat tgtggaacaa ttcacgaatc atcggctctt tttgtttcgt
    11641 atttgaaaga acaaactcac caaataa
//
LOCUS       DARYSY010000196         5505 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. zooepidemicus isolate Culture
            SAMN27589286-rid16720693.guided.082, whole genome shotgun sequence.
ACCESSION   DARYSY010000196 DARYSY010000000
VERSION     DARYSY010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN27589286
            Sequence Read Archive: SRR18760068
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574947.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574947.1
            Genome Coverage       :: 102x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,093
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 2,007
            CDSs (with protein)               :: 2,007
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 26 of 53
            Pseudo Genes (incomplete)         :: 24 of 53
            Pseudo Genes (internal stop)      :: 16 of 53
            Pseudo Genes (multiple problems)  :: 12 of 53
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5505
                     /organism="Streptococcus equi subsp. zooepidemicus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN27589286-rid16720693.guided.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="zooepidemicus"
                     /db_xref="taxon:40041"
                     /country="USA: AL"
                     /collection_date="2019-06-11"
                     /collected_by="Auburn University Bacteriology and Mycology
                     Diagnostic Laboratory, Auburn, AL"
     gene            79..858
                     /locus_tag="TVR04_002089"
     CDS             79..858
                     /locus_tag="TVR04_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1270733.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKDGRVFIYFTVEEIMRRRNISKPTAIKTLDELDMKKGIGLIERVR
                     LGLGKPNVIYVKDFMSILAVKENDFQKSKNLTSEVKDFNLRSKENELQEVQNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLTAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            855..1706
                     /locus_tag="TVR04_002090"
     CDS             855..1706
                     /locus_tag="TVR04_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1270734.1"
                     /translation="MMKELEKVMIEDVEYSYDPEKEYIKDGHAFCKVCHERKDGKVME
                     FFDNKMIFKISCKCDRDREEREKERQKQMEIERLKSSCFNSIIQWSYTFENYQGEENQ
                     SLIIAKNFVKDYEEMKKENIGLLFYGSVGSGKTYLACSIANSLIEQYQIGVKIRNFAQ
                     IINELQKGGFDFDKNAYIESLVNTSVLILDDLGIERDTSYAKEQVYNIVNNRYLKQKP
                     TIFTTNLSYDTIQNCKDSVEYQRIYSRIIEMCIPVMVVGEDFRKVIQKDKLNRNKDRL
                     LNGGERS"
     gene            1703..2188
                     /locus_tag="TVR04_002091"
     CDS             1703..2188
                     /locus_tag="TVR04_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1270735.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNTNGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKERGKYSVF
                     FQAKDMKVMDKAFKHALSESEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            2185..3966
                     /locus_tag="TVR04_002092"
     CDS             2185..3966
                     /locus_tag="TVR04_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEL1270736.1"
                     /translation="MIDKILKDIKGLFKVQDKVKFLKQNIPYLAFFYIGNIFSHHVRA
                     YIGGDIIDKIFQGILEINTMSFLPSLHPTDIIMGVVVAVLIKIIVYTKGKNVKKFRQG
                     KEYGSARWGNKKDIEPYMDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKSGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDDETYMNPIDRLFEALEKREPTHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIRELRDLMSEDELELDTLGDRKTALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDNADTIVGNCDSTLFLGGKEKTTLKELSETLGKETIDLYNTSETRSNQK
                     SFGLNYQKTGKELMSQDEITVMDGGKCIFQLRGVRPFLSDKFDITKHKNYKFLEDYDK
                     KNVFDIEEYIKRKGKVKLNRNTVITRL"
     gene            4048..>5505
                     /locus_tag="TVR04_002093"
     CDS             4048..>5505
                     /locus_tag="TVR04_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HEL1270737.1"
                     /translation="MSTIKIENLTFSYYGYVKPIFENVSFSFDTNWKTGLIGRNGIGK
                     STLFKLLLNQEVYKGKISKSVDFIKFPPNISDTSKLGIELYEELISDEEEWKLFRELN
                     LLNVDENLVYREFETLSKGEQTKILLAILFTKQDGFLLIDEPTNHLDMDGRKIVSEYL
                     KSKKGFLLISHDRDFLDGCINHVISINRNSIDVQSGNFTSWYENKVMKDRFEISQNEK
                     LRKDIKRLKEAARQSKIWSDKIENTKNGVKVSGVKPDKGHIGHQSAKMMKKSKNLENR
                     QNKAIEEKQSLLKDIETKESLLLHPLHHHKSPLISVSNLSSCYGERQILSNVSFEIKQ
                     ADIVAIYGQNGSGKSTLIKILLGLHHEYIGEIKSASNLKISYIPQDTSNLTGSLNEYI
                     HKQGVDETLCKTILRKLDFARELFEMDMKNYSDGQKKKVLIAASLSKPAHLFVWDEPL
                     NYIDVISRIQIEEIIKEAKPTLIFVEHDKRFVEDIA"
BASE COUNT         2163 a          736 c         1105 g         1501 t
ORIGIN      
        1 aaaatggtta ccaaagacga tagagaaaaa aactatcgtc tttttctttg taaaatttta
       61 aggaaaggag gtgaagcgat ggactttgac tatttctata acagagaagc ggaaagattt
      121 aactttctaa aagtaccgga gatattggta gacggagaag aatttaaggg attatccgct
      181 gaagcgatta tcctttattc aatgcttctt aaacggacag gaatgtcttt taagaataac
      241 tggatagaca aagatggcag ggtatttatc tattttactg ttgaagaaat tatgagaaga
      301 agaaatatct caaagccgac agctataaaa acattagatg aactcgatat gaagaaagga
      361 atcggactga ttgaaagagt aaggcttggg cttggtaagc cgaatgtcat atatgttaaa
      421 gactttatga gcatattagc ggtaaaagaa aatgactttc agaagtcaaa aaacttaact
      481 tcagaagtaa aagattttaa cctcagaagt aaagaaaatg aacttcagga agttcaaaat
      541 cttgactcta actatataga gaataataag agtaagtata gtaagagaga atatagtttt
      601 ggtgaaaacg ggcttggaac atttcaaaat gtatttttaa cggcagaaga tatatccgat
      661 ttacaaatca taatgaactc acagcttgat aattacattg agagattatc tgcatatatc
      721 aaaagcaccg gaaagaccta taaagaccat aaagcgacaa tcctttcttg gttttataaa
      781 gatcagggga gaggaaaaga agtgaaaaca tcaaatatcc cgacatggga agaatatgat
      841 aaaggagaac acctatgatg aaagaattag aaaaagtaat gatagaagat gtagagtatt
      901 cttacgatcc tgaaaaagaa tatatcaagg atggacacgc attttgtaaa gtttgccatg
      961 aaagaaaaga cggaaaagtg atggagttct ttgataacaa gatgatattt aagatttctt
     1021 gcaaatgcga tagagataga gaggaaagag aaaaagaaag acaaaagcag atggagattg
     1081 aacgattaaa gagtagctgc tttaactcga ttattcagtg gtcatacaca tttgaaaatt
     1141 atcagggaga agaaaatcaa agccttatca ttgcaaagaa ctttgtaaaa gactatgagg
     1201 aaatgaaaaa agaaaatatc ggacttcttt tttatggctc agtaggtagc ggaaagacct
     1261 atcttgcctg ctccattgca aatagcctta ttgaacagta tcaaataggc gttaaaataa
     1321 gaaattttgc acagattatc aatgaactgc aaaagggagg atttgatttt gacaagaacg
     1381 catatattga atcccttgta aatacttccg ttcttatctt ggatgactta ggaatagaaa
     1441 gagatacaag ctatgctaaa gagcaagtat ataacatcgt gaataacagg tacttaaaac
     1501 agaaaccgac tatcttcact actaaccttt cctacgacac aatccaaaat tgtaaggata
     1561 gcgtagagta tcaaagaatc tactcaagaa tcatagagat gtgtattcct gttatggttg
     1621 taggagaaga ttttagaaag gttattcaaa aggacaaact gaatcggaat aaggacagac
     1681 tgctgaatgg aggtgagaga agttgatcaa tgaagaaata gcaagaaaaa cactgaatat
     1741 ggaagttaga gctgctaaag taacaggaaa gctaattctg aacttgttaa agaaattgat
     1801 gaaagaagca gaaaaacttg gaggacttga aaagctggtt aatactaacg gaaatgaagt
     1861 aaagctaaaa gatatggtta aaaaggggca gcttgaagaa attccagttg aagaagcaga
     1921 acttaaggaa ctcaaaaagg aacttaatcg gtatggggta aagttttcag tcatgaaaga
     1981 taaggaaaga gggaaatact cagtattctt tcaagctaaa gatatgaagg ttatggacaa
     2041 agcatttaag catgcccttt cagaatcaga aaagaaaacg gaaaggaagg agtccattca
     2101 taagaatatt gagaagttta aggagatggc taaaaactct gtttccaaag ataaaatcaa
     2161 gaataaacaa aaggagcaga gcctatgata gataaaatat taaaggacat caaaggctta
     2221 tttaaggtgc aagataaggt aaagtttcta aagcaaaaca ttccctatct tgcatttttc
     2281 tatataggta atatcttttc acatcatgta agagcctata taggtggcga tattattgac
     2341 aaaatttttc aagggatatt agagattaat acgatgagct ttcttccaag ccttcatcct
     2401 acggatatta taatgggcgt ggtagtagct gttttaatca aaattatcgt atataccaaa
     2461 gggaaaaatg ttaaaaagtt tagacagggg aaagagtatg gctcagcaag atggggaaat
     2521 aagaaagata ttgagccata catggatgaa aagtttcaaa acaatatctt gcttacgcaa
     2581 acagaacgcc taactatgaa tggtagacca gctaatccta aatatgctcg taacaaaaat
     2641 gtgcttgtaa tcggtggatc aggaagtggg aaaacgagat tttatgtaaa accgaatctt
     2701 atgcagatgc actcgtcata ttgtgtaacc gatcctaaag gaactatagt ccttgagtgc
     2761 ggtaagatgc ttgaagataa cggatatgag ataaaaatcc taaataccat taacttcaaa
     2821 aagtctatga aatacaatcc ctttgcttat cttagaagtg aaaaagacat actaaaatta
     2881 gtacagacaa tcatcgcaaa caccaaggga gagggagaaa aatcaggtga ggatttttgg
     2941 gtaaaagccg aaaaactcta ctacacagca cttatcggct acatcttcta tgaagctcca
     3001 agagaagaaa agaactttgc gactctactc gatatgatag atgcttctga agtcagagaa
     3061 gatgatgaaa cctatatgaa tcccatagat agactctttg aagcacttga aaaaagagag
     3121 ccgacacact ttgcagtgaa gcaatataaa aagtacaaat tggctgccgg aaaaacggca
     3181 aaatctattc ttatctcttg tggtgcaagg cttgctccat ttgatattag ggaacttagg
     3241 gacttgatga gtgaagatga acttgagctt gatacactcg gagatagaaa aacggcactc
     3301 tttgttatta tctctgatac tgatgatacc tttaactttg tagtatccat tatgtactca
     3361 caacttttta atctcttatg tgataaggcg gatgatgtat atggcggacg attacctgtc
     3421 catgtgagat gcttgcttga tgaatttgca aacatcggct taattccaaa gtttgagaaa
     3481 cttatagcaa caatccgttc cagagaaata tcagcaagta tcatacttca agcacaatct
     3541 cagttaaagg caatctataa ggataatgcc gatacaatcg taggtaactg tgatagtacc
     3601 ttgttccttg gtggcaagga gaaaactaca ctaaaagaat tgtctgaaac actgggaaaa
     3661 gaaacgatag atttatataa cacatcggaa acaaggtcaa atcaaaagtc tttcggactt
     3721 aattatcaaa agacaggtaa ggaactgatg agccaagatg agattactgt aatggacggt
     3781 ggtaaatgta tttttcagct tagaggtgta agaccttttc tttcagataa attcgacatc
     3841 acaaagcata agaactataa gttcttagaa gattatgaca agaagaatgt gtttgatatt
     3901 gaagaatata taaagagaaa aggcaaggtt aagcttaata gaaatacggt aattacaaga
     3961 ttgtaagatt tactgttata actatatggt cgagggtata tttgatataa tagagctaga
     4021 taaatttgaa tttgaggggg tgtttttgtg tcaacaatta aaattgaaaa cctcactttc
     4081 tcatattatg gctatgtaaa acctatattt gaaaatgtat cattttcatt tgatacgaac
     4141 tggaaaacag ggctaatagg aagaaacgga attggaaaat caacactatt caagctactt
     4201 ctaaaccaag aagtttataa ggggaaaatc agcaaaagtg ttgactttat taaattccca
     4261 cccaatataa gcgatacttc aaaattagga attgagttat atgaagaact aatatcagat
     4321 gaggaagaat ggaaactatt tagagaactt aacttgctaa atgtagatga gaatcttgtt
     4381 tacagagagt ttgaaacact ttctaaagga gaacaaacaa aaatcctttt agctattttg
     4441 tttacaaaac aagatggttt tttacttatt gatgaaccaa caaaccattt agatatggac
     4501 ggaagaaaaa ttgtaagtga atatcttaaa agtaaaaaag gttttttgct catatctcat
     4561 gatagagatt ttttagatgg ctgtatcaat catgtaattt ctattaacag gaattctatt
     4621 gatgttcaat caggaaattt tacatcatgg tatgaaaaca aagtgatgaa agaccgattt
     4681 gaaatcagtc aaaatgagaa attaagaaag gatattaaac gattaaaaga agctgcaaga
     4741 caaagtaaaa tttggtcaga taaaattgaa aatactaaaa atggcgtgaa agtatctggt
     4801 gtaaaaccgg ataaaggaca tattgggcat caatctgcca agatgatgaa gaaatccaag
     4861 aatttggaga atagacaaaa caaggcaata gaagaaaaac agagtttgct aaaagatatt
     4921 gaaacaaagg aaagtctatt attgcatcca ttacatcatc ataaaagtcc tctaatatcg
     4981 gttagcaatt tatcatcatg ctatggagaa agacagatat taagcaatgt aagtttcgag
     5041 ataaaacaag ccgatatagt ggctatatat ggtcaaaatg gtagtggaaa atcaactttg
     5101 attaaaattt tgttagggtt acatcatgag tatattggtg aaataaaatc ggcaagtaat
     5161 ttaaaaatat cgtatattcc tcaagataca tctaatttaa caggtagcct aaatgagtat
     5221 attcataagc aaggtgttga tgaaacattg tgtaaaacaa ttcttaggaa attagatttt
     5281 gcaagagaat tatttgaaat ggatatgaag aactatagcg atggacaaaa aaagaaagtt
     5341 ttaatcgctg caagtttgtc aaaaccagct catttatttg tttgggacga accgctaaat
     5401 tatatagatg taatatcgag aatacagatt gaggaaatta taaaagaagc aaaacctaca
     5461 ctcatatttg tggagcatga taagagattt gtagaagata tagct
//
